| P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
|---|
| 1.385e-276 | -635.19 | FOSTER_TOLERANT_MACROPHAGE_DN | MSigDB lists | FOSTER_TOLERANT_MACROPHAGE_DN | 375 | 305 | 15632 | 1249 |
Slc2a6,Ifi208,Nfkbid,Dgka,Junb,Snx10,Cd86,Pik3r6,Gca,Tnfsf10,Prkx,Il15ra,Ptprj,Traf3ip2,Dusp5,Fndc3a,Pim1,Mob3b,Ptgs2,Il12b,Nr3c1,Dennd1b,Setdb2,Rffl,Ifi213,Parp8,Dync1h1,Plekhf2,Otud1,Ifi205,Nod1,Daxx,Mxd1,Hhex,Pml,Spata13,Sphk1,Bcl9,Zc3h7a,Flnb,Slc39a14,Abtb2,Il10,Gna15,Plekha2,Gbp7,Tnfsf4,Etnk1,Il13ra1,Socs3,Aida,Slc25a22,Tmem171,Ikzf1,Slc44a1,Il6,Hivep2,Tet2,Tiparp,Rnd3,Ppfibp1,Samhd1,Nfkbiz,Ccl22,Phip,Etv3,Tmtc2,Il4ra,Trim26,Spint2,Cxcl2,Fzd1,Pde4b,Myadm,Lcp2,Plekha4,Vps54,Vcam1,Mitd1,Inpp1,Epsti1,Atp10a,Xkr8,Tlr3,Tmem229b,Usp42,Rcan1,D1Ertd622e,Tnc,Itgb8,Arhgap26,Mafk,Errfi1,Tlk2,Arid5a,Rhbdf2,Sgk3,Lipg,Ncoa7,Prpf38a,Tnfaip3,Ch25h,Upp1,Gbp3,Rnd1,Csf1,Trim21,Mmd,Etv6,Jdp2,Ppp1r15b,Nfkb1,Hdc,Cenpj,Adap2,Mndal,Plod2,Whamm,Jak2,Fscn1,Rap2c,Dusp16,Cdkn1a,Nfil3,Pmepa1,Dram1,Sema4c,Tor1aip2,Katna1,Vcan,Rin2,Gramd1a,Il15,Slc16a1,Ifi207,Prpf4,Slfn5,Tle3,Col18a1,Dcp2,Slc30a1,Ifi214,Arl4a,Rilpl1,Wdr59,Noc4l,Slc4a7,Nampt,Jarid2,Samsn1,Daam1,Ppm1k,Nfxl1,Plaur,Fmnl2,Sec24b,Dnaja2,Gpr84,Minpp1,Tbc1d1,Zfp800,Cebpd,Src,Gypc,N4bp1,Hspa1a,Gpsm2,Cd40,Bfar,Cd83,Mapkbp1,Notch1,Myo10,Malt1,Irf2,Slc30a4,Rhoh,Ddx58,Il1a,Socs1,Traf1,Slco3a1,Sertad3,Akt3,Pdss1,Cd69,Dcp1a,Ifi203,Mier3,Tmem219,Socs7,Armc8,Kpna3,Endod1,Casp7,Mtmr14,Filip1l,Ppa1,Rcn1,Edn1,Rai14,Kremen1,Tra2a,Chst11,4932438A13Rik,Nlrc5,Ezr,Agrn,Fos,Zyx,Pfkfb3,Pnpt1,Angpt1,Vcpip1,Ccnd2,Plagl1,Icosl,Ext1,Mmp13,Igsf9,Gja1,Hopx,Fzd5,Golga3,Serpine1,Gcnt2,Snn,Il1b,Gng4,Pcgf5,Ripk2,Frmd4a,Il18,Map3k8,Stat3,Batf2,Cp,Tnfsf8,Ubtd2,Glipr2,Aebp2,Ogfrl1,Stat5a,Phldb1,Homer1,Arhgef3,Mtus1,Tpst1,Tcf4,Ifi209,Gnb4,Gda,Apaf1,Aim2,Csrnp1,Zfp281,Tab2,F11r,Ifih1,Ifi211,Cnn3,Zfp36,Usp12,Stx6,Vezt,Rel,Cav1,Nos2,Col27a1,Lhx2,Wdr43,Dgkh,Rac3,Uaca,Cacnb3,Odc1,Lpar1,Ifi204,Map2k4,Asb13,Pla2g4a,Parp14,Ctsc,Dusp2,Lrch1,Gadd45g,Spsb1,Itgav,Cited2,Trip10,Sdc4,Aff1,Klf7,Foxp4,Spred1,Dusp14,Rbl1,Olr1,Atp11b,Evl,Fas,Nek6,Ubash3b,Znrf3,Mpp7 |
| 6.307e-102 | -233.02 | immune system process | biological process | GO:0002376 | 1895 | 395 | 20694 | 1406 |
Nlrc5,Kdr,Gbp9,Kitl,Cx3cl1,Irgm1,Myd88,Arid5a,Gch1,Fcgr2b,Cxcl14,Vcam1,Notch2,Tagap,Rab10,Egr1,Rgcc,Bcl6,Cgas,Il1rn,Il6,Psme2,Hif1a,Ciita,Jag1,Cd34,Slfn8,Cacnb3,Trem1,Sema4a,Samhd1,Ctsc,Itgav,Gja1,Casp3,Rtp4,Ikbkg,Relb,Tnfsf14,Nr4a3,Slc7a2,Psme1,Fubp1,Mapkapk2,Iigp1,Trim12a,Cxcl1,Ap3b1,Ccl7,Fcgr1,Gbp2,Tlr9,Pf4,Parp14,Ddit4,Tgtp1,Klf2,Ifih1,Csf3r,Ccrl2,Dennd1b,Fcgr4,Rnf19b,Ppp4r2,Ccl9,Oas1b,Ebi3,Klrk1,Pdgfb,Cxcl10,Ikbke,Batf2,Smpdl3b,H2-Ab1,Stat3,Hck,Src,Lcn2,Lst1,Ampd3,Hcls1,Tapbp,Gbp3,Crkl,Stat1,Nlrc4,Il12rb1,Tarm1,Cxcl3,Adar,Ripk3,H2-Q4,Optn,Dnase1l3,Pou2f2,Swap70,Mndal,Syk,Ccl4,Sod2,Oasl1,Ccl3,Ifi204,Milr1,Prdm1,Rab20,Zyx,Pml,Ccr1,Ciapin1,Fgr,Ankrd17,Igf1r,Ifnb1,Nod1,Trim14,Ccl5,Cxcl2,Serpinb9,Rnf31,Pde4b,Oas2,Treml2,Gsdmd,Malt1,Junb,Fpr1,C3,Cd74,Tlr1,Atm,Ifit1bl1,Cd80,Ifit1,Gbp2b,Il18bp,Olr1,Bcl2a1d,Cd38,H2-M2,Isg20,Rab32,Lmo4,Ifit1bl2,Sell,Lyn,Tnip1,Il4ra,C1rl,Ifi209,Ahr,Clcf1,Fam20c,H2-T24,Trim13,Hp,Irf8,Axl,Dhx58,Tap1,Hhex,Mcoln2,Ptger4,Shfl,Aim2,Cdc42ep4,S100a8,Tnfsf4,Tent2,Sp110,Trim21,Stap1,Nod2,Nfkbid,H2-Q7,Tap2,Irak3,Gadd45g,Cxcl9,Ifi208,Parp9,Irgm2,Ifna4,Gbp4,Nos2,Csf3,Cdc42ep2,Icosl,Xcr1,Tapbpl,Ptprj,Nmi,Stx11,Tnfsf8,Flnb,Themis2,Mx2,Clec4e,Tlr2,Clec4d,Hmox1,Irak2,Tiparp,Cd300lf,Itgal,Slamf7,Ifi44,Rhoh,Notch1,H2-Aa,Ifna6,Nck1,Gpr35,Tnfsf10,Trim56,Nampt,Casp8,Stxbp3,Tnip3,Ifitm1,Bnip3,Ifi214,Ednrb,Cd14,Psmb10,Cd55,Il12b,Traf3ip2,Mefv,Nfkb2,G3bp2,Cnn2,Tnfsf9,Ifi205,Nfkbiz,Tlr3,Ifnar1,H2-T10,Tnfrsf14,Oas1g,Nfkb1,Prkce,Trim34a,Ifna1,Tet2,Pmaip1,Il1b,Isg15,Azi2,Herc6,Apobec3,Slfn9,Ifna2,Arid4a,Map3k8,Stat5a,Pdpn,Eif2ak2,Slamf8,Nfkbia,Evl,Psmb9,Oas3,Ccl2,Batf,Ppp1r14b,Psmb8,H2-Q6,Ifit3,Csf1,Hcar2,Il15,Ccl8,Pdgfrb,Cebpd,Ptpn2,Fzd5,Ch25h,Prkx,Etv6,Lif,Raet1e,Oas1a,Flt1,Arg2,Heatr9,Tnfsf15,Cd300e,Treml4,Bcl2l11,Bcl2a1a,Fpr2,Stat2,Snx10,Trim12c,Ifit3b,Map2k1,Dock10,Zbp1,Tcea1,Jak2,Tlr6,Lcp2,Inhba,Tnfaip3,Irf7,Ddx58,Clec4n,Ifi211,P2ry14,Tnfrsf1b,Itga9,Zc3hav1,Nlrp3,Rnf135,Cited2,Stxbp1,Jun,Rsad2,Tnf,Il1a,Pilrb1,Il27,Prdx1,Angpt1,Ikzf1,Rasgrp1,Ccl12,Gbp8,Cd40,Jmjd6,Icam1,Cd180,Nt5c3,Nfil3,Slpi,H2-Eb1,Ifit2,Oasl2,Pik3cd,Spn,Plscr1,Cd86,Dbnl,Sqstm1,Samd9l,Acod1,Cav1,Osm,Trim30a,Cxcl11,Pbx1,Ccl22,Plcl2,Sirt1,Lgals9,Cd274,Cmklr1,Gbp7,Serpina3g,Irf1,Cx3cr1,H60b,Il10,Irf2,Fas,Itga4,Dtx3l,Irf4,C1ra,Ddx60,Ccr3,Ifna5,Tifa,Ripk2,Tmod3,Casp4,Trim26,Clec5a,Ifi203,Casp1,Jarid2,Rrs1,Il18rap,Mx1,Marco,Sbds,H2-T22,Gpr18,Zc3h12a,Il18,Fgl2,Sele,Gfi1,Serpinb9b |
| 8.408e-101 | -230.43 | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP | 193 | 133 | 15632 | 1249 |
Zbp1,Rbm43,Fcgr1,Adar,Tap1,Slc28a2,Samhd1,Tlr6,Sass6,Irgm2,Ikzf1,Samd9l,Il18bp,Cd200r4,Ccl12,Ifit1bl1,Znfx1,Tnfaip2,Dck,Stat1,Etnk1,Ifi35,Aida,Irf1,Oas1a,Rnf31,P4ha1,Psmb8,Gbp7,Casp4,Ifit3,Irf8,Il10,Hck,Gbp2,Daxx,Ifit1,Mthfr,Pml,Psme1,Sell,Trim12c,Isg15,Dtx3l,Ddx58,Cd180,Stat2,Pnp2,Setdb2,Gbp4,Mlkl,Tapbp,Casp1,Apobec3,Cd40,Timp1,Psmb9,Tnfsf10,Prkx,Slfn9,Tfec,Trafd1,Cmpk2,Lacc1,Oas1g,Rnf19b,Herc6,Tapbpl,Cxcl10,Serpinb9,Slamf8,Nmi,Ube2l6,Oas2,Uba7,Wars,Gch1,Nampt,Ifit1bl2,Snx10,Samsn1,Slamf7,Il15,Slfn5,Hk3,Stxbp1,Rtp4,Slfn8,Parp14,Tor1aip2,Parp9,Aoah,Eif2ak2,Gsdmd,Oasl1,Dennd2a,Ifit3b,Lyn,Parp11,Psme2,Trim21,Isg20,Xaf1,Tor3a,Casp8,Lipg,Gnb4,Gbp3,Psmb10,Ifih1,Usp18,Batf2,Ifi44,Gbp9,Dhx58,Rsad2,Ifit2,Oas3,P2ry13,Arid5a,Inpp1,Sp110,Epsti1,Parp3,Tlr3,Il2rg,Tmem229b,Parp12,Bst1,Ccl5,Irf7,Lcp2,Cd274 |
| 8.438e-95 | -216.61 | GSE7348_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE7348_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN | 152 | 115 | 15632 | 1249 |
Rnf14,Nfkb1,Rel,Lmo4,Nos2,Trim21,Csf1,Nfkbib,Rtn2,Mtdh,Jak2,Ccl4,Gbp2b,Dusp16,Klf3,Sod2,Gpr18,Stap1,Ift57,Ifnb1,Fas,Nck1,Zbtb5,Il15,Il27,Ahr,Zc3hav1,Plek,Lcp2,Reps1,Sap30,Mmp13,Ripk2,Osgin2,Map3k8,Arid5b,Gpr85,Pcdh7,Vcam1,Sp110,Ptges,Ddhd1,Arhgef3,Oaf,Itgb8,Rab11fip1,Nupr1,Ifih1,Psmb10,Tnfaip3,Plagl2,Prpf38a,Birc3,Abtb2,Zc3h12c,Casp4,Heatr6,Flnb,Ampd3,Plscr1,Hivep3,Ccrl2,Rasgrp1,Cd69,Mtmr14,Tnfsf4,Socs3,Dyrk2,Irf1,Acsl1,Cflar,Tnip1,Tnfaip2,Tagap,Socs7,Adhfe1,Hivep2,Psmd10,Edn1,Peli1,Igsf6,Nod2,Atf3,Mapkapk2,Pttg1,Cdc42ep2,Rgl1,Pik3r6,Btg2,Ube2l6,Slc2a6,Stx11,Ptprj,Arl5c,Ptgs2,Pim1,Clec5a,Rsbn1,Zhx2,N4bp1,Ttc39c,Birc2,Cd40,Tank,Cish,Malt1,Marcksl1,Il1a,Icam1,Isg15,Traf1,Socs1,Cd83,Tal2,Relb |
| 4.335e-94 | -214.98 | HALLMARK_INTERFERON_GAMMA_RESPONSE | MSigDB lists | HALLMARK_INTERFERON_GAMMA_RESPONSE | 205 | 132 | 15632 | 1249 |
Psmb9,Cd40,Casp1,C1ra,Tapbp,Casp3,Gbp4,Pnp2,Stat2,Hif1a,Icam1,Ddx58,Isg15,Socs1,Irf2,H2-Q7,Psme1,Pml,Nod1,Cd86,Ifit1bl2,Nampt,Gch1,Wars,Oas2,Ube2l6,Nmi,Ptgs2,Pim1,Fpr1,Cxcl10,Herc6,Il15ra,Trafd1,Cmpk2,Cmklr1,Tnfsf10,Znfx1,Nlrc5,H2-Q4,Ifit1bl1,Nfkbia,Ccl12,Il18bp,Samd9l,Irf4,Peli1,Il6,Il4ra,Samhd1,Tap1,Ciita,Fcgr1,Adar,Pnpt1,Zbp1,Ifit3,Irf8,Casp4,Ogfr,Psmb8,Rnf31,Stat4,Cd69,St3gal5,Plscr1,Irf1,Casp7,Ifi35,Socs3,Stat1,Tnfaip2,H2-Q6,Oas3,Ifit2,Fgl2,Rsad2,Dhx58,Stat3,Ifi44,Gbp9,Batf2,Usp18,Upp1,Cd74,Ifih1,Psmb10,Gbp3,Cd38,Tnfaip3,Mvp,Myd88,Lcp2,Cd274,Irf7,Pde4b,Ccl5,Parp12,Trim26,H2-Aa,Arid5b,Ripk2,Epsti1,Sp110,Vcam1,Gpr18,Ptpn2,Eif2ak2,Sod2,Parp14,Pla2g4a,Arl4a,P2ry14,Rtp4,Fas,Ddx60,Il15,Slamf7,Lap3,Casp8,Nfkb1,Xaf1,Tdrd7,Isg20,Trim21,Trim14,Psme2,Mthfd2,Ifit3b,Oasl1,Cdkn1a,Jak2 |
| 2.282e-90 | -206.41 | GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN | 191 | 125 | 15632 | 1249 |
Gadd45b,Bcl2a1b,Ptpn2,Parp14,Stap1,Mllt6,Ift57,Dusp4,Fas,Sdc1,Fpr2,Ubash3b,Nr1h3,Pilra,Klf7,Tor3a,Jdp2,Ednrb,Gem,Pstpip2,Srxn1,Csf1,Ppp4r2,Alas1,Stx6,C3,Rab20,Jak2,Ifit2,Zswim4,Nfkbie,Gpr68,Rsad2,Plk3,Nupr1,Usp18,Fabp3,Ube2f,Hvcn1,Irak3,Plek,Igsf9,Gdf15,Nrp2,Ext1,Vasn,Vasp,St3gal1,Ripk2,Rcan1,Nr4a3,Il2rg,Cxcl1,Ralgds,Nfkb2,Il1b,Ifit1bl1,Nlrc5,Flrt3,Agrn,Znfx1,Psmd10,Edn1,Il4i1,Ccl2,Il6,Ncoa5,Atf3,Nfkbiz,Lrp8,Egr1,Nlrp3,Plau,Clec4n,Birc3,Zc3h12c,Casp4,Procr,Ccrl2,Jag1,Smpdl3b,Met,Kpna3,Mtmr14,Ebi3,Dyrk2,Tlr2,Acsl1,Gpd2,Cflar,Fam20c,Dusp1,Swap70,Slc2a1,Gpr84,Slc15a3,Egr2,Bcl2a1d,Malt1,Marcksl1,Traf1,Isg15,Ifit1,Relb,Junb,Ifit1bl2,Slc7a8,Gch1,Lad1,Cd86,Slc7a2,Pdgfb,Slc2a6,Phlda1,Nfkbid,Tmem26,Stx11,Dusp5,Clec5a,Ttc39b,Serpinb9,Bcl2a1a,Cmpk2,Zhx2,Hcar2 |
| 6.067e-90 | -205.43 | GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_DN | MSigDB lists | GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_DN | 192 | 125 | 15632 | 1249 |
Rnf114,Srm,Ass1,Aoah,Spic,Tor1aip2,Parp14,Ctsc,Ddx60,Nr1h3,Fpr2,Il15,Spred1,Hk1,S100a8,Tor3a,Hdc,Mov10,Alas1,Tifa,Oasl1,Itga5,Dram1,Ifit3b,Rab20,Cacnb3,Cdkn1a,Ddhd1,Ifit2,Tnf,Klf6,Ifi44,Dhx58,Rsad2,Nfkbie,Psmb10,Usp18,F11r,Upp1,Ube2f,Lipg,1600014C10Rik,Batf,Gnb4,Tnfaip3,Mvp,Ccl5,Irf7,Rrs1,Cd274,Slfn4,Tap2,Sap30,Bst1,Hp,Mitd1,Stip1,Rcl1,Znfx1,Tspan3,Fos,Myc,Irgm2,Triobp,Nfkbiz,Zbp1,Pnpt1,Tap1,Psmb8,Clec4n,Ogfr,Gbp7,Lcn2,Casp4,Ifit3,Flnb,Procr,Akt3,Hat1,Eef1e1,Ccrl2,Oas1a,Socs3,Stat1,Kpna3,Ifi35,Mefv,Aida,Rgs1,Cflar,Trem1,Cd40,Timp1,Psmb9,Pnp2,Tapbp,Marcksl1,Sell,Fgr,Socs1,Stat2,Hck,Relb,Ifit1,Snx10,Samsn1,Lgals9,Cd86,Noc4l,Nmi,Ube2l6,Oas2,Uba7,Wars,Oas1g,Tapbpl,Clec4d,Fpr1,Slamf8,Clic4,Slfn3,Cmpk2,Hcar2,Trafd1,Gng12 |
| 7.678e-90 | -205.19 | GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | 189 | 124 | 15632 | 1249 |
Nfkb1,Tnfrsf1b,Gem,Lmo4,Rel,Zfp36,Zeb1,Pstpip2,Cnn3,Itga5,Ptgir,Egr3,Rab20,Ccl4,Jak2,Ppfibp2,Sod2,Gadd45b,Nr4a1,Ets2,Spic,Mmp14,Dusp2,Ift57,Mllt6,Fas,Fpr2,Clec4e,Sdc4,Olr1,Spred1,Foxp4,Pde4b,Slfn4,Lcp2,Ppp1r15a,Icosl,Gpr132,Cxcl2,Vasp,Nr4a3,Rcan1,Ralgds,Nfkb2,Irak2,Ikbke,Il1b,Snn,Tnf,Stat5a,Nfkbie,Aebp2,Hdac1,Csrnp1,Nupr1,Prdm1,Ube2f,Tnfaip3,Mier3,Birc3,Casp4,Zc3h12c,Cd69,Hivep3,Ccrl2,Filip1l,Dyrk2,Socs3,Mtmr14,Tlr2,Mefv,Irf1,Tnfaip2,Tnip1,Cflar,Tagap,Nfkbia,Il4i1,Mapkapk2,Egr1,Nfkbiz,Nlrp3,Ccl22,Cdc42ep2,Ciita,Slc31a2,Junb,Jarid2,Samsn1,Cd86,Slc2a6,Maff,Stx11,Nfkbid,Dusp5,Zc3h12a,Dnaja2,Ptger4,Kdm6b,Rnf19b,Ptprj,Cxcl10,Serpinb9,Pim1,Ptgs2,Slfn3,Ppp6r1,N4bp1,Dusp1,Ehd1,Cd40,Swap70,Fchsd2,Gpr84,Marcksl1,Slc30a4,Traf1,Isg15,Icam1,Spata13,Il1a,Cd83,Hck,Relb |
| 1.290e-85 | -195.47 | GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN | 186 | 120 | 15632 | 1249 |
Hspa1a,Dusp1,Ehd1,Spryd7,Zfp800,Bcl2a1d,Gpr84,Dusp8,Slc15a3,Egr2,Icam1,Traf1,Isg15,Malt1,Ier2,Gbp2,Cd83,Bmp2,Nampt,Nfkbid,Hk2,Stx11,Maff,Pdgfb,Btg2,Phlda1,Rnf19b,Kdm6b,Ptger4,Dusp5,Zc3h12a,Dnaja2,Dio2,Plaur,5430427O19Rik,Bcl2a1a,Slfn3,Il1rn,Fos,Tiparp,Flrt3,Sbds,Bcl2l11,Tmem171,Myc,Ccl2,Etv3,Trim13,Atf3,Slc25a25,Cdc42ep2,Zc3h12c,Il10,Tnfsf14,Ptch1,Rabgef1,Birc3,Abtb2,Ccrl2,Cd69,Plscr1,Irf1,Tlr2,Mtmr14,Ebi3,Filip1l,Cflar,Rgs1,Tnfaip2,Arid5a,Bcl6,Klf6,Nfkbie,Sele,Aebp2,Irgq,Fam133b,Usp18,Ch25h,Csrnp1,Nupr1,Slfn4,Osm,Med21,Serpine1,Plek,Ccl5,Gdf15,Gja1,Mmp13,Rapgef2,Fam72a,Arl5b,Osgin2,Map3k8,Ripk2,Il1b,Cited2,Gadd45b,Sod2,Bcl2a1b,Sqstm1,Itgav,Ifnb1,Dusp4,Spred1,Klf7,Dusp14,Extl2,Pim3,Slamf7,Clec4e,Rel,Cav1,Kctd12,Rab20,Frmd6,Nfil3,Gfpt1,Ccl4 |
| 1.590e-85 | -195.26 | GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | 164 | 113 | 15632 | 1249 |
Nupr1,Mcoln2,Rnd1,Cd14,Gys1,Irak3,Tnfaip3,Tnf,Slc25a37,Arid5a,Csf3r,Rbpms,Glipr2,Rsad2,Ripk2,Adora2b,Map3k8,Cxcl1,Vcam1,Ikbke,Nfkb2,Gcnt2,Ptges,Il1b,Pde4b,Plek,Ccl5,Cd274,Wdfy1,Rapgef2,Mmp13,Cxcl2,Fas,Cyth3,Clec4e,Slamf7,Gadd45b,Sod2,Dusp2,Optn,Rin2,Dtx2,Tnip3,Ccl4,Dusp16,Tnfrsf1b,Nfkb1,Nos2,Hdc,Zfp36,Alas1,Nfkbib,Stx6,Malt1,Mxd1,Hif1a,Il1a,Slco3a1,Dusp1,Ttc39c,Cd40,Slc2a1,Slc15a3,Carhsp1,Stk40,Smox,Fndc3a,Ptgs2,Pim1,Fpr1,Il12b,Clec4d,Il1rn,Clic4,Fmnl2,Il15ra,Slc13a3,Samsn1,Ascc3,Sipa1l1,Inpp5b,Hk2,Stx11,Nfkbiz,Dmxl2,Pfkfb3,Nfkbia,Hivep2,Pik3r5,Slc7a11,Ccl12,Tet2,Edn1,Il6,Pdpn,Gpr35,Ebi3,Ell2,Socs3,Cd200,Cflar,Tnip1,Tnfaip2,Trem1,Il10,Casp4,Lcn2,Procr,Ampd3,Smpdl3b,Slc39a14,Ccrl2,Cd69 |
| 3.940e-84 | -192.05 | HALLMARK_TNFA_SIGNALING_VIA_NFKB | MSigDB lists | HALLMARK_TNFA_SIGNALING_VIA_NFKB | 193 | 121 | 15632 | 1249 |
Kdm6b,Ptger4,Rnf19b,Dusp5,Zc3h12a,Ptgs2,Il12b,Cxcl10,Bcl2a1a,Serpinb2,Plaur,Il15ra,Nampt,Junb,Gch1,Plk2,Klf2,Btg2,Phlda1,Slc2a6,Maff,Ier2,Mxd1,Lif,Il1a,Icam1,Ddx58,Sphk1,Traf1,Cd83,Bmp2,Relb,Ehd1,Dusp1,Birc2,Tank,Egr2,Ccnd1,Bcl2a1d,Cebpd,Socs3,Irf1,Ier3,Tlr2,Cflar,Clcf1,Tnip1,Tnfaip2,Birc3,Jag1,Ccrl2,Cd69,Atf3,Egr1,Plau,Pfkfb3,Tap1,Nfkbia,Ccl12,Fos,Jun,Tiparp,Edn1,Il6,Myc,Ripk2,Rcan1,Map3k8,Il18,Nr4a3,Cxcl1,Nfkb2,Il1b,Snn,Pde4b,Plek,Ccl5,Ppp1r15a,Fosb,Serpine1,Icosl,Inhba,Cxcl2,Ifih1,Tnfaip3,Klf6,Tnf,Stat5a,Ifit2,Bcl6,Sat1,Tnc,Nfkbie,Dram1,Egr3,Dnajb4,Trib1,Ccl4,Ldlr,Nfil3,Pmepa1,Cdkn1a,Nfkb1,Rel,Gem,Csf1,Zfp36,Irs2,Sdc4,Cd80,Olr1,Spsb1,Nr4a1,Gadd45b,Bcl2a1b,Sod2,Sqstm1,Trip10,Ets2,Dusp2,Dusp4 |
| 2.888e-82 | -187.75 | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN | 191 | 119 | 15632 | 1249 |
Atf3,Egr1,Nlrp3,Mark2,Slc7a11,Znfx1,Tiparp,Tmem171,Irf4,Edn1,Ccl2,Slc44a1,Igsf6,Ebi3,Ell2,Filip1l,Dyrk2,Irf1,Tnip1,Fam20c,Socs7,Il10,Cd69,Ier2,Slc30a4,Hif1a,Isg15,Bmp2,Ifit1,Dusp1,Ctu1,Spryd7,Ttc39c,Otud1,Tank,Tbc1d1,Rffl,Slc15a3,Pde1b,Egr2,Zfp800,Bcl2a1d,Kdm6b,Dnaja2,Clec4d,Il1rn,Bcl2a1a,Clic4,Plaur,Dcbld2,Tfec,Snx10,Nampt,Slc31a2,Slc7a2,Btg2,Pdgfb,Nck1,Sdc4,Slamf7,Spred1,Klf7,Dusp14,Bcl2a1b,Cited2,Parp14,Dusp2,Katna1,Optn,Egr3,C3,Arf4,Frmd6,Nfil3,Dcun1d3,Csf1,Zfp36,Kctd12,Nupr1,Csrnp1,Mcoln2,Cd74,Zfp281,Ifih1,Fabp3,Gbp3,Arg2,Rgs3,Apaf1,Plagl2,Stat5a,Slc25a37,Arid5a,Bcl6,Serp1,Rhbdf2,Oaf,Sele,Tlk2,Rsad2,Ccng2,St3gal1,Pcdh7,Vcam1,Cxcl1,Ikbke,Irak2,Ppp2r2a,Sp110,Gja1,Fzd5,Cd274,Serpine1,Rrs1,Med21,Gpr132,Sap30,Vasp,AA467197 |
| 1.203e-81 | -186.32 | GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_DN | 160 | 109 | 15632 | 1249 |
Trim13,Pgs1,St3gal3,Chmp4b,Phf11c,Adar,Zbp1,Znfx1,Sbds,Nod2,Ikzf1,Igsf6,Phf11d,Sema4a,Ebi3,Nox1,Kpna3,Socs3,Denr,Stard7,Pfkl,Tagap,Cflar,Tmem123,Tnfaip2,Zc3h12c,Layn,Ankib1,Clic5,Rnf31,Procr,Agtrap,Jmjd6,Psme1,Tank,Src,Ehd1,Psma6,Setdb2,Larp1,Zc3h12a,Gng12,Cmpk2,Zhx2,Glrx,Acsl5,Tnfsf10,Slc4a7,Stx11,Tlr1,Nck1,Tmem176b,Spred1,Foxp4,Sdc4,Il15,Pilra,Phf11a,Trip10,Gramd1a,Ppp1r14b,Ap3b1,Ift57,Stap1,Cacnb3,Itga5,Mob3c,Lrrc8c,Hdc,Rnf14,Dcun1d3,Stx6,Etv6,Tmem176a,Isg20,Psme2,Rtn2,Nfkbib,Usp18,Csrnp1,Mvp,Plagl2,Batf,Cd14,Ifit2,Phf11b,Slc16a3,Fgl2,Rbpms,Rsad2,Rab21,Cp,St3gal1,Xkr8,Atp10a,Psmb6,Ripk2,Pcgf5,Rcl1,Epsti1,Ralgds,Cd274,Lcp2,Map2k1,Hsd17b12,Rapgef2,Parp12,Tbc1d13,Reps1 |
| 5.508e-81 | -184.80 | defense response | biological process | GO:0006952 | 1120 | 269 | 20694 | 1406 |
Thbs1,Slfn8,Trem1,Rel,Samhd1,Bmp2,Il6,9930111J21Rik1,G3bp2,Hif1a,Ciita,Saa3,Trim34a,Slc7a2,Ifna1,Acp5,Mapkapk2,Il1b,Isg15,Nfkbiz,Tlr3,Itgav,Gja1,Rtp4,Ifnar1,Tnfrsf14,Relb,Oas1g,Ifna6,Irgm1,Myd88,Trim56,Nampt,Arid5a,Gch1,Fcgr2b,Nlrc5,H2-Aa,Gm5431,Gbp9,Cx3cl1,Ifitm1,Bcl6,Bnip3,Mmp25,Cd14,Ccdc88b,Cd55,Il12b,Kdm6b,Cgas,Il1rn,Mefv,Stxbp3,Notch2,Tagap,Smpdl3b,Treml4,H2-Ab1,Stat3,Hck,Lcn2,Fpr2,Stat2,Gbp3,Tapbp,Ifit3b,Raet1e,Klrk1,Cxcl10,Oas1a,Arg2,Ptafr,Ikbke,Batf2,Optn,Plac8,Clec4n,Ifi47,Tnfrsf1b,Zc3hav1,Nlrp3,Sphk1,Zbp1,Timp1,Stat1,Jak2,Tlr6,Nlrc4,Tnfaip3,Irf7,Il12rb1,Tarm1,Cxcl3,Ddx58,Adar,Fcgr1,Slamf8,Gbp2,Pf4,Tlr9,Evl,Oas3,Batf,Ccl2,Ppp1r14b,Parp14,Ddit4,Ifit3,Gm4951,Mecp2,Herc6,Apobec3,Slfn9,Ifna2,Iigp1,Trim12a,Stat5a,Cxcl1,Eif2ak2,Ccl7,Ccl8,Gm12185,Rnf19b,Clec2d,Oas1b,Ccl9,Tgtp1,Ifih1,Ccrl2,Csf1,Nupr1,Pik3cd,Spn,Plscr1,Isg20,Cd86,Ifit1bl1,Slpi,Gbp2b,H2-Eb1,Ifit1,Olr1,Ifit2,Oasl2,Ptgs2,Ccl22,Hp,Trim13,Axl,Irf8,Dhx58,Tap1,Acod1,Ifit1bl2,Lyn,Tnip1,Il4ra,Cxcl11,C1rl,Trim30a,Sdc1,Spire1,Prdm1,Il27,Prdx1,Rab20,Zyx,Pml,Ccr1,Rasgrp1,Ccl12,Stat4,Rnf135,Syk,Stxbp1,Ccl4,Jun,Rsad2,Tnf,Oasl1,Ccl3,Il1a,Oas2,Malt1,Gsdmd,Fpr1,C3,Cd74,Cd180,Nt5c3,Tlr1,Fgr,Gbp8,Ankrd17,Cd40,Nox1,F830016B08Rik,Nod1,Ifnb1,Trim14,Ccl5,Serpinb9,Cxcl2,Icam1,Casp4,Trim26,Clec5a,Cdc42ep2,Casp1,Nmi,Il18rap,Tnfsf8,Stx11,Cxcl9,Tifa,Ripk2,Parp9,Irgm2,Ifna4,Gbp4,Nos2,Irak2,Zc3h12a,Slamf7,Il18,Sele,Gm4841,Notch1,Flnb,Mx1,Marco,Themis2,Mx2,Clec4e,Clec4d,Tlr2,Hmox1,Irf1,Cdc42ep4,Cx3cr1,S100a8,Il10,H60b,Irf2,Acvr1,Tnfsf4,Mcoln2,Ptger4,Cmklr1,Gbp7,Shfl,Aim2,Adora2a,Dtx3l,Irf4,C1ra,Ddx60,Tgtp2,Ccr3,Ptgir,Sp110,Trim21,Serpine1,Nod2,Pla2g7,Nfkbid,Igtp,H2-Q7 |
| 3.424e-80 | -182.98 | GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_DN | MSigDB lists | GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_DN | 193 | 118 | 15632 | 1249 |
Il1a,Icam1,Spata13,Fgr,Traf1,Ier2,Marcksl1,Relb,Hck,Cd83,Cd40,Rbbp8,Ehd1,Dusp1,N4bp1,Ifnar1,Bcl2a1d,Gpr84,Cish,Pim1,Serpinb9,Cxcl10,Il12b,Kdm6b,Ptger4,Dusp5,Dcbld2,Il1rn,Bcl2a1a,Plk2,Cd86,Samsn1,Junb,4930523C07Rik,Gch1,Maff,Btg2,Pdgfb,Slc2a6,Ccl22,Nlrp3,Nfkbiz,Cx3cr1,Pik3r5,Flrt3,Il6,Il4i1,Igsf6,Irf1,Acsl1,Ier3,Tlr2,Kpna3,Socs3,Dyrk2,Tagap,Cflar,Kdr,Tnip1,Tnfaip2,Zc3h12c,Casp4,Rnf19a,Hivep3,Ccrl2,Cd69,Gbp3,Arg2,Prdm1,Csrnp1,Mcoln2,Hvcn1,Cd14,Ube2f,Stat5a,Phldb1,Ddhd1,Aebp2,Errfi1,Nfkbie,Adora2b,Il2rg,Map3k8,Nr4a3,St3gal1,Cxcl1,Nfkb2,Ralgds,Osm,Gdf15,Rapgef2,Vasp,Gpr132,Cx3cl1,Nck1,Fas,Bcor,Foxp4,Slamf7,Spic,Ets2,Gadd45b,Nr4a1,Sod2,Bcl2a1b,Ifrd1,Dusp2,Rab20,Egr3,Ptgir,Itga5,Cdkn1a,Gfpt1,Cep350,Hdc,Pstpip2,Tifa,Zfp36 |
| 3.882e-80 | -182.85 | GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_DN | MSigDB lists | GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_DN | 154 | 106 | 15632 | 1249 |
Daxx,Mdfic,Slc30a4,Malt1,Hif1a,Slco3a1,Isg15,Socs1,Traf1,Setdb2,Dbnl,Lztfl1,Acvr1,Gypc,Timp1,Rgs14,Il1rn,Cmpk2,Rnf19b,Zc3h12a,Nmi,Tnfsf15,Stoml1,Snx10,Gch1,Samsn1,Sipa1l1,Pfkfb3,Samhd1,Tap1,Atf3,Nfkbiz,Dtwd1,Edn1,Il6,Nod2,Il18bp,Triobp,Hivep2,Pik3r5,Sbds,Znfx1,Cflar,Kdr,Ifi35,Irf1,Slc25a22,Procr,Flnb,Hivep3,Cd69,Rabgef1,Mier3,P4ha1,Ifit3,Zc3h12c,Sav1,Lipg,Tnfaip3,Plagl2,Aim2,F11r,Usp18,Gbp3,Batf2,Tnfsf8,Mafk,Nfkbie,Tpst1,Nfkb2,Gcnt2,Sp110,Fam53c,Atp10a,Pcgf5,Adora2b,Sh3bp4,Parp12,Spint2,Tbc1d13,Brd2,Fzd5,Serpine1,Il27,Enpp4,Spred1,Olr1,Dnase1l3,Fas,Stxbp1,Aldh1b1,Ggct,Ap3b1,Spsb1,Sod2,Mrpl52,Jak2,Sema4c,Itga5,Dtx2,Parp11,Lyn,Ifit3b,Nfkbib,Xaf1,Ppp1r15b |
| 2.857e-79 | -180.85 | GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_UP | MSigDB lists | GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_UP | 192 | 117 | 15632 | 1249 |
Casp2,Ccrl2,Oas1a,Ogfr,Casp4,Gbp7,Ifit3,Psmb8,Fam111a,Irf1,Aida,Ppa1,Socs3,Stat1,Etnk1,Ifi35,Irf4,Irgm2,Znfx1,Tap1,Samhd1,Chmp4b,Rbm43,Zbp1,Pnpt1,Adar,Pttg1,Ccnd2,Oas2,Cnp,Gch1,Nampt,Trafd1,Cmpk2,Tnfsf10,Clic4,Slfn9,Slfn3,Cxcl10,Ttc39b,Oas1g,Rnf19b,Tapbp,Cish,Gbp4,Gpsm2,Psmb9,Plekhf2,N4bp1,Apobec3,Gbp2,Daxx,Notch1,Ifit1,Socs1,Isg15,Icam1,Stat2,Pml,Tdrd7,Syne2,Isg20,Trim21,Mov10,Hk1,Rnf14,Tor3a,Frmd6,Ifit3b,Asb13,Pim2,Oasl1,Parp9,Gadd45g,Slfn8,Parp14,Tor1aip2,Tmem184b,Ets2,Rnf114,Eif2ak2,Morc3,Rbl1,Rtp4,Gmppb,Ddx60,Parp12,Trim26,Map2k1,Irf7,Vps54,Slfn4,Cd274,Tor1aip1,Keap1,Epsti1,Map3k8,Cox18,Ripk2,B3gnt5,Dhx58,Rsad2,Fgl2,Ogfrl1,Ifi44,Gbp9,Stat3,Tpst1,Ifit2,1600014C10Rik,Myd88,Gbp3,Psmb10,Ifih1,Zfp281,Usp18,Nupr1 |
| 3.531e-78 | -178.34 | GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_DN | MSigDB lists | GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_DN | 188 | 115 | 15632 | 1249 |
Psme1,Lif,Icam1,Traf1,Socs1,Slco3a1,Gbp2,Timp1,Cd40,Gpr84,Pnp2,Slc15a3,Tapbp,Bcl2a1d,Zc3h12a,Oas1g,Cxcl10,Lox,Bcl2a1a,Il1rn,Tnfsf10,Clic4,Il15ra,Trafd1,Plk2,Wars,Csf3,Adora2a,Maff,Pgs1,Atf3,Nfkbiz,Rras2,Zbp1,Chmp4b,Tap1,Nfkbia,Ccl12,Agrn,Fos,Edn1,Ccl2,Chst11,Ebi3,Ppa1,Socs3,Rcn1,Irf1,Ier3,Cflar,Tnfaip2,Psat1,Marco,Il10,Ubr4,Ogfr,Flnb,Oas1a,Ccrl2,Ch25h,Upp1,F11r,Gnb4,Lipg,Cd14,Tnfaip3,Mvp,Tnf,Txnrd1,Tpst1,Oaf,Batf2,Glipr2,Aebp2,Dhx58,Ripk2,Cox18,Cxcl1,Plat,Ptges,Ccl5,Tor1aip1,Irf7,Serpine1,Wdfy1,Mmp13,Car13,Il12rb1,Cxcl2,Parp12,Rtp4,Cx3cl1,Il15,Sgcb,Tspo,Aoah,Spsb1,Gadd45b,Bcl2a1b,Tor1aip2,Mmp14,Ifrd1,Gadd45g,Oasl1,Cacnb3,Ccl4,Cdkn1a,Nfil3,Abcc1,Tor3a,Mov10,Lap3,Pstpip2,Psme2,Rhou |
| 6.823e-77 | -175.38 | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP | 195 | 116 | 15632 | 1249 |
Ifi35,Dck,Aida,Ms4a6d,Azi2,Zcchc2,Cflar,Cd300lf,Rnaset2b,P4ha1,Rnf31,Casp4,Gbp7,Oas1a,Pttg1,Xrn1,Fcgr1,Rbm43,Zbp1,Chmp4b,Samhd1,Tap1,Nlrc5,Agrn,Ccl12,Msr1,Znfx1,Irf4,Ccl2,Gpr35,Samd9l,Larp1,Oas1g,Il12b,Cxcl10,Slfn3,Nfxl1,Tnfsf10,Il15ra,Trafd1,Glrx,Gch1,Cd86,Cnp,Rnaset2a,Ube2l6,Nmi,Uba7,Oas2,Pml,Mthfr,Rab19,Ddx58,Isg15,Dtx3l,Slco3a1,Cd83,Ahsa1,Ifit1,Casp1,Psmb9,Gpsm2,Gbp4,Dennd1b,Pnp2,Dbnl,Ccnd1,Mlkl,Lyn,Rap2c,Adam19,Cdkn1a,Tor3a,Rnf14,Mov10,Isg20,Slamf9,Ddx60,Sdc4,Il15,Zc3hav1,Gsdmd,Tmem184b,Parp14,Ctsc,Fcgr2b,Aftph,S1pr2,Phlpp1,Vcan,Parp9,Scarf1,Naa25,Tlr3,Phyh,Frmd4a,Epsti1,Pgk1,Ccl5,Slfn4,Trim26,Sap30,H2-Aa,Snx2,Mmp13,Pde7b,Parp12,Psmb10,Rnf34,Ncoa7,Prpf38a,Arid5a,Oas3,Gbp9,Fgl2,Rsad2 |
| 1.058e-76 | -174.94 | GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_UP | MSigDB lists | GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_UP | 192 | 115 | 15632 | 1249 |
Aida,Irf1,Fam111a,Etnk1,Ifi35,Stat1,Ppa1,Ifit3,Ogfr,Gbp7,Psmb8,Ccrl2,Oas1a,Casp2,Chmp4b,Tap1,Samhd1,Rbm43,Zbp1,Adar,Pnpt1,Znfx1,Agrn,Irgm2,Peli1,Cxcl10,Traf3ip2,Oas1g,Cmpk2,Trafd1,Slfn3,Tnfsf10,Slfn9,Lgals9,Cnp,Nampt,Sesn3,Oas2,Noc4l,Nmi,Stat2,Sell,Isg15,Sertad3,Psme1,Pml,Daxx,Notch1,Ifit1,Cd164,Gbp2,Crlf3,Psmb9,Gpsm2,Apobec3,N4bp1,Tapbp,Gbp4,Ifit3b,Asb13,Oasl1,Pmepa1,Wdr43,Mov10,Casp8,Tor3a,Rnf14,Hk1,Tdrd7,Zeb1,Isg20,Trim21,Psme2,Rtp4,Ddx60,Rbl1,Atp11b,Tmem184b,Crbn,Eif2ak2,Morc3,Rnf114,Phlpp1,Parp9,Slfn8,Parp14,Tor1aip2,St7,Rcl1,Keap1,Mitd1,Inpp1,Tor1aip1,Cd274,Slfn4,Map2k1,Golga3,Irf7,Vps54,Parp12,Trim26,Usp18,Gbp3,Ifih1,Rnf135,Psmb10,Rab3ip,1600014C10Rik,Oas3,Ifit2,Ddhd1,Rsad2,Dhx58,Ifi44,Gbp9 |
| 1.879e-76 | -174.37 | regulation of immune system process | biological process | GO:0002682 | 1330 | 289 | 20694 | 1406 |
Mapkapk2,Il1b,Isg15,Slc7a2,Ifna1,Tnfrsf14,Tnfsf14,Prkce,Nr4a3,Ifi205,Nfkbiz,Tlr3,Casp3,H2-T10,Samhd1,Ctsc,Thbs1,Cacnb3,Tnfsf9,Prnp,Il2rg,Jag1,Lox,Il6,Dusp1,Acvr1b,Hif1a,Cst7,Ccdc88b,Cd55,Cgas,Traf3ip2,Il12b,Cnot4,Bcl6,Ifi214,Samsn1,Cd14,Notch2,Tnip3,Rgcc,Cxcl14,Vcam1,Cdkn1a,Casp8,Arid5a,Fcgr2b,Sdc4,Nck1,Tmem176a,Irgm1,Myd88,P2ry12,Kitl,Cx3cl1,Nlrc5,Ubash3b,H2-Aa,Kdr,Zc3hav1,Mndal,Nlrp3,Ifi211,Dnase1l3,Tnfrsf1b,Swap70,Tnfaip3,Irf7,Trib1,Inhba,Tarm1,Il12rb1,Cd200,Ddx58,Adar,H2-Q4,Ripk3,Sphk1,Zbp1,Crkl,Tlr6,Lcp2,Stat1,Nlrc4,Fpr2,Hcls1,Trim12c,Treml4,Gpr68,Smpdl3b,Peli1,H2-Ab1,Egr3,Stat3,Lrch1,Ikbke,Klrk1,Lif,Raet1e,Usp12,Flt1,Cxcl10,Ptafr,Arg2,Zeb1,Clec2d,Nr1h3,Myc,Pde5a,Phf11a,Fzd5,Ptpn2,Fcgr4,A530064D06Rik,Dennd1b,Csf1,Il15,Hcar2,Ifih1,Csf3r,Ezr,Parp14,H2-Q6,Trafd1,Slamf8,Fcgr1,Tlr9,Nfkbia,Pf4,Ccl2,Cxcl1,Stat5a,Ap3b1,Socs1,Eif2ak2,Slfn1,Vegfc,Apobec3,Il15ra,Lgals9,Axl,Pik3r6,Dhx58,Cd274,Tap1,Cd83,H2-T24,Plcl2,Mmp9,Sirt1,Sell,Cav1,Lyn,Slc7a11,Tnip1,Il4ra,Ifi209,Ahr,C1rl,Trim30a,Clcf1,Acod1,Adora2b,Cd86,Hsph1,Pik3cd,Cd38,Spn,H2-M2,Plscr1,Bcl2a1d,Fos,Abr,Atm,Cd80,Parp3,Cd74,C3,Tlr1,Rnf31,Pde4b,Malt1,Treml2,Fpr1,Ifnb1,Nod1,Irs2,Rabgef1,Serpinb9,Ccl5,Hk1,Icam1,Ankrd17,Fgr,Cd40,Ccr1,Pml,Ccl12,Rasgrp1,Milr1,Prdm1,Pilrb1,Il27,Ikzf1,Angpt1,Jun,Rsad2,Tnf,Il1a,Ccl3,Ifi204,Rnf135,Syk,Ccl4,Stxbp1,Gfi1,Sele,Notch1,Irak2,Cd300lf,Slamf7,Itgal,Zc3h12a,Fgl2,Il18,Themis2,H2-T22,Clec4e,Gpr18,Pim1,Hmox1,Clec4d,Tlr2,B430306N03Rik,Pvr,Ifi203,Ldlr,Nmi,Ptprj,Tapbpl,Il18rap,Nfkbil1,Mtus1,Icosl,Csf3,Ripk2,Ifi208,Mul1,Parp9,Hlx,Tifa,Irgm2,Gbp4,Wdfy1,Tmem178,Traf2,Htra1,C1ra,Ddx60,Mmp14,Nectin2,Dtx3l,Irak3,Itga4,Irf4,Ctla2a,Zfp36,Serpine1,Tmem176b,Nfkbid,Nod2,Pla2g7,Lrp8,H2-Q7,Tap2,Fas,Edn1,Stap1,Elmod2,Il10,H60b,Tnfsf4,Phlpp1,Irf1,Aim2,Adora2a,Ptger4,Cmklr1,Bst1 |
| 7.087e-75 | -170.74 | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN | 183 | 111 | 15632 | 1249 |
Spry2,Ccl2,Myc,Fos,Jun,Tiparp,Bcl2l11,Slc25a25,Cdc42ep2,Etv3,Trim13,Atf3,Mapkapk2,Ccrl2,Cd69,Plscr1,Zc3h12c,Il10,Ptch1,P2ry2,Rabgef1,Birc3,Socs7,Cflar,Tnfaip2,Irf1,Tlr2,Ier3,Mtmr14,Itpkc,Zfp800,Bcl2a1d,Gpr84,Egr2,Otud1,Hspa1a,Dusp1,Ehd1,Spryd7,Relb,Cd83,Bmp2,Icam1,Hif1a,Marcksl1,Malt1,Mxd1,Ier2,Nfkbid,Stx11,Btg2,Phlda1,Plk2,Plaur,5430427O19Rik,Bcl2a1a,Slfn3,Pim1,Ptgs2,Kdm6b,Rnf19b,Dusp5,Zc3h12a,Dnaja2,Ifrd1,Dusp4,Dusp2,Cited2,Gadd45b,Bcl2a1b,Sod2,Sqstm1,Klf7,Slamf7,Clec4e,Cdk5r1,Kctd12,Nfkbib,Rel,Cep350,Gem,Dusp16,Frmd6,Ccl4,Dnajb4,Odc1,Rab20,Errfi1,Nfkbie,Sele,Irgq,Arid5a,Klf6,Cd14,Fam133b,Csrnp1,Nupr1,Mmp13,Fam72a,Slfn4,Fzd5,Osm,Plek,Ccl5,Gja1,Gdf15,Il1b,Cldnd1,Frmd4a,Map3k8,Ripk2 |
| 2.083e-74 | -169.66 | immune response | biological process | GO:0006955 | 1001 | 244 | 20694 | 1406 |
Il1b,Isg15,Ifna1,Tnfrsf14,Relb,Tnfsf14,Prkce,Nr4a3,Tlr3,H2-T10,Ifnar1,Sema4a,Ctsc,Samhd1,Tnfsf9,Trem1,Ciita,Jag1,Il6,Nfkb2,G3bp2,Cd55,Traf3ip2,Cgas,Il1rn,Il12b,Mefv,Bcl6,Ifitm1,Cd14,Notch2,Rgcc,Stxbp3,Cxcl14,Trim56,Arid5a,Gch1,Fcgr2b,Ifna6,Irgm1,Tnfsf10,Myd88,Cx3cl1,Nlrc5,H2-Aa,Gbp9,Zc3hav1,Nlrp3,Clec4n,Optn,Dnase1l3,Pou2f2,P2ry14,Tnfrsf1b,Swap70,Tnfaip3,Irf7,Tarm1,Cxcl3,Il12rb1,Adar,Ddx58,H2-Q4,Zbp1,Tlr6,Jak2,Stat1,Nlrc4,Lcn2,Stat2,Lst1,Gbp3,Dock10,Treml4,Smpdl3b,H2-Ab1,Hck,Stat3,Tnfsf15,Ikbke,Klrk1,Lif,Raet1e,Cxcl10,Arg2,Rnf19b,Ccl9,Ccl8,Dennd1b,Csf1,Il15,Ifih1,Tgtp1,Ccrl2,Parp14,H2-Q6,Ifit3,Gbp2,Fcgr1,Evl,Pf4,Tlr9,Ppp1r14b,Ccl2,Oas3,Batf,Trim12a,Cxcl1,Eif2ak2,Ccl7,Herc6,Apobec3,Iigp1,Ifna2,Trim13,Irf8,Axl,Dhx58,Cd274,Tap1,H2-T24,Plcl2,Ccl22,Sirt1,Lyn,Osm,Il4ra,Cxcl11,C1rl,Trim30a,Dbnl,Acod1,Isg20,Cd86,Pik3cd,Spn,H2-M2,Plscr1,Il18bp,Ifit2,Oasl2,Nfil3,Cd80,Slpi,H2-Eb1,Ifit1,Gbp2b,Cd74,Cd180,C3,Tlr1,Oas2,Gsdmd,Malt1,Nod1,Ifnb1,Serpinb9,Cxcl2,Trim14,Ccl5,Icam1,Gbp8,Ankrd17,Fgr,Igf1r,Zyx,Ccr1,Pml,Ccl12,Rasgrp1,Milr1,Prdm1,Il27,Prdx1,Rab20,Rsad2,Tnf,Oasl1,Ccl3,Il1a,Rnf135,Syk,Ccl4,Stxbp1,Serpinb9b,Ifi44,Notch1,Slamf7,Itgal,Fgl2,Il18,Mx2,H2-T22,Clec4e,Tlr2,Clec4d,Flnb,Marco,Mx1,Xcr1,Casp1,Nmi,Tnfsf8,Stx11,Il18rap,Casp4,Trim26,Clec5a,Cdc42ep2,Icosl,Csf3,Parp9,Ripk2,Tifa,Ifna4,Irgm2,Nos2,Gbp4,Cxcl9,Ifna5,C1ra,Ccr3,Dtx3l,Gadd45g,Irf4,Nod2,Tap2,H2-Q7,Fas,Sp110,Trim21,Cx3cr1,S100a8,H60b,Il10,Tnfsf4,Cdc42ep4,Irf1,Shfl,Serpina3g,Aim2,Mcoln2,Ptger4,Gbp7 |
| 2.238e-74 | -169.59 | GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_UP | MSigDB lists | GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_UP | 195 | 114 | 15632 | 1249 |
Hcar2,Bcl2a1a,Il1rn,Serpinb2,Clic4,Ptgs2,Kif3c,Rnf19b,Ptprj,Dusp5,Csf3,Hk2,Stx11,Slc2a6,Samsn1,Lad1,Slc7a2,Jarid2,4930523C07Rik,Gch1,Relb,Cd83,Il1a,Trim12c,Malt1,Pml,Stk40,Gsr,Bcl2a1d,Gbp4,Hspa1a,Slc2a1,Spryd7,Agpat4,Esd,Zcchc2,Cflar,Kpna3,Ebi3,Filip1l,Dyrk2,Cd200,Stat1,Stat4,Jag1,Procr,Ampd3,Ifit3,Ogfr,Casp4,Clec4n,Birc3,P4ha1,Adar,Igsf6,Rai14,Pdpn,Znfx1,Rhof,Nfkbia,Nlrc5,Slc7a11,Agrn,Pik3r5,Ptges,Vcam1,Osgin2,Rcan1,Nr4a3,Map3k8,Hp,Irf7,Plek,Gdf15,Irak3,Traf5,Fabp3,Gbp3,Mcoln2,Nfkbie,Ccng2,Batf2,Gbp9,Rhbdf2,Zswim4,Slc16a3,Abcc5,Cdkn1a,Frmd6,Col27a1,Ifit3b,Hmgcs1,C3,Itga5,Trim21,Psme2,Cav1,Tor3a,Foxp4,Zc3hav1,Slfn5,Slamf7,Rtp4,Tpi1,Mllt6,Ifrd1,Ift57,Parp9,Tor1aip2,Mmp14,Stap1,Ptpn2,Syk,Bcl2a1b |
| 2.488e-74 | -169.48 | GSE19198_1H_VS_6H_IL21_TREATED_TCELL_DN | MSigDB lists | GSE19198_1H_VS_6H_IL21_TREATED_TCELL_DN | 188 | 112 | 15632 | 1249 |
Myd88,Lipg,Ube2f,Atp11a,Psmb10,Stat3,Aebp2,Ogfrl1,Rsad2,Ddhd1,Tpst1,Ralgds,Ptges,Keap1,Hp,Ripk2,Il18,Sap30,Stxbp3,Bst1,Tor1aip1,Irf7,Vps54,Col4a2,Spred1,Rbl1,Ddx60,Stxbp1,Fpr2,Parp14,Aoah,Srm,Rnf114,Tmem184b,Znrf1,Ccl4,Dusp16,Cdkn1a,Nfil3,Pmepa1,Itga5,Cacnb3,Mthfd2,Ifit3b,Asb13,Tifa,Atm,Jdp2,Hk1,Mov10,Hdc,Pml,Hif1a,Il1a,Fgr,Sell,Ccdc86,Cst7,Psmb9,Timp1,Cd40,Acsl5,Thbs1,Prkx,Clic4,Il15ra,Gng12,Hcar2,Zc3h12a,Dnaja2,Clec4d,Lox,Ttc39b,Serpinb9,Fpr1,Ube2l6,Maff,Uba7,Txn1,Junb,Samsn1,Rbm43,Fcgr1,Tap1,Rars,Pgs1,Tlr6,Ccnd2,Myc,Bbx,Il6,Map3k6,Tspan3,Fos,Tiparp,Cd300lf,Socs3,Rcn1,Tlr2,Mefv,Procr,Akt3,Plscr1,Flnb,Slc39a14,Psmb8,Psat1,Ifit3,Il10,Irf8,Ogfr,Casp4 |
| 3.826e-74 | -169.05 | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_DN | 158 | 103 | 15632 | 1249 |
Il15ra,Cmpk2,Slamf8,Serpinb9,Rnf19b,Wars,G3bp2,Stoml1,Oas2,Rilpl1,Cnp,Nampt,Notch1,Gbp2,Nod1,Icam1,Ddx58,Isg15,Slco3a1,Psme1,Pml,Atp13a1,Mlkl,Setdb2,Psmb9,Cflar,Phf11d,Azi2,Slc25a22,Stat1,Ppa1,Ifit3,Ogfr,Abtb2,Rnf31,Samhd1,Phf11c,Herc3,Zbp1,Nmral1,Lrp8,Il18bp,Tspan3,Nlrc5,Epsti1,Keap1,Ikbke,Slc29a3,Map3k8,Atp10a,Rapgef2,Il12rb1,Mmp13,Pde7b,Parp12,Trim26,Cd274,Irf7,Csrp1,Traf5,Myd88,Psmb10,Gbp3,Nupr1,Treml2,Cers6,Stat3,Tpst1,Phf11b,Cdkn1a,Clcn7,Fscn1,Ccl4,Gbp2b,Cacnb3,Ifit3b,Tlr9,C3,Tdrd7,Etv6,Trim14,Trim21,Csf1,Psme2,Mov10,Cenpj,Slfn5,Dnase1l3,Zc3hav1,Sgcb,Il15,Phf11a,Tspo,Dcp2,Gmppb,Rtp4,Ddx60,Tor1aip2,Parp14,Mmp14,Plac8,Aoah,Rnf114 |
| 8.216e-74 | -168.29 | response to other organism | biological process | GO:0051707 | 1193 | 268 | 20694 | 1406 |
Tifa,Parp9,Ripk2,Irgm2,Ifna4,Gbp4,Tab2,Nos2,Slfn4,Cxcl9,Cmpk2,Casp1,Nmi,Tnfsf8,Stx11,Casp4,Trim26,Nfkbil1,Clec5a,Cdc42ep2,Mx2,Clec4e,Clec4d,Tlr2,Nfkbib,Flnb,Mx1,Marco,Gfi1,Rgs1,Ifi44,Slfn2,Irak2,Zc3h12a,Slamf7,Il18,Shfl,Aim2,Mcoln2,Ptger4,Gbp7,Cx3cr1,S100a8,H60b,Il10,Irf2,Tnfsf4,Irf1,Cdc42ep4,Serpine1,Nod2,Tap2,H2-Q7,Sp110,Trim21,Stap1,Resf1,C1ra,Ddx60,Ptgir,Irak3,Dtx3l,Irf4,Zfp36,Abr,Ifit2,Oasl2,Ptgs2,Ifit1bl1,Cd80,Slpi,H2-Eb1,Ifit1,Gbp2b,Adgrl2,Isg20,Cd86,Pik3cd,Spn,Plscr1,Cav1,Lyn,Il4ra,Cxcl11,C1rl,Trim30a,Usp18,Acod1,Ifit1bl2,Lgals9,Hp,Trim13,Irf8,Axl,Dhx58,Cd274,Ccl22,Ier3,Jun,Rsad2,Oasl1,Tnf,Ifi204,Ccl3,Rnf135,Syk,Stxbp1,Ccl4,Zyx,Pml,Ago3,Ccl12,Prdx1,Prdm1,Ly6a,Il27,Rab20,Noct,Ifnb1,Nod1,Trim14,Ccl5,Serpinb9,Cxcl2,Mtdh,Fgr,Gbp8,Ankrd17,Cd40,C3,Cd180,Nt5c3,Tlr1,Pde4b,Oas2,Gsdmd,Malt1,Junb,Ikbke,Batf2,Serpina3f,Raet1e,Klrk1,Cxcl10,Oas1a,Tmem229b,Arg2,Ptafr,Lcn2,Fpr2,Stat2,Gbp3,Ifit3b,Smpdl3b,Treml4,Peli1,H2-Ab1,Bcl2l11,Hck,Irf7,Tnfaip3,Trib1,Il12rb1,Tarm1,Cxcl3,Adar,Ddx58,Zbp1,Stat1,Tlr6,Jak2,Nlrc4,Zc3hav1,Mndal,Nlrp3,Plac8,Optn,Ifi211,Clec4n,Tnfrsf1b,Cxcl1,Trim12a,Eif2ak2,Ccl7,Herc6,Apobec3,Slfn9,Ifna2,Iigp1,Parp14,Ifit3,Ddit4,Fcgr1,Slamf8,Gbp2,Pf4,Nfkbia,Tlr9,Psmb9,Evl,Ccl2,Oas3,Batf,Ppp1r14b,Csf1,Tgtp1,Ifih1,Rnf19b,Oas1b,Ccl9,Nr1h3,Ccl8,Fcgr4,Fzd5,Tent5a,Ciita,Cflar,Saa3,Il6,G3bp2,Samhd1,Bmp2,Slfn8,Trem1,Tnfrsf14,Oas1g,Nfkb1,Prkce,Ifi205,Tlr3,Itgav,Rtp4,Ifnar1,Mapkapk2,Il1b,Isg15,Trim34a,Ifna1,Acp5,Cx3cl1,Mt2,Nlrc5,H2-Aa,Plaat3,Gbp9,Trim56,Arid5a,AA467197,Gch1,Fcgr2b,Ifna6,Nck1,Irgm1,Myd88,Notch2,Tagap,Tnip3,Stxbp3,Ccdc88b,Cd55,Il12b,Il1rn,Cgas,Mefv,Ifitm1,Bnip3,Ednrb,Cd14 |
| 1.212e-73 | -167.90 | response to external biotic stimulus | biological process | GO:0043207 | 1195 | 268 | 20694 | 1406 |
Saa3,Cflar,Ciita,G3bp2,Il6,Samhd1,Bmp2,Trem1,Slfn8,Prkce,Oas1g,Nfkb1,Tnfrsf14,Ifnar1,Itgav,Rtp4,Tlr3,Ifi205,Isg15,Il1b,Mapkapk2,Acp5,Ifna1,Trim34a,Cx3cl1,Mt2,Gbp9,Plaat3,H2-Aa,Nlrc5,Fcgr2b,Gch1,Arid5a,AA467197,Trim56,Myd88,Irgm1,Ifna6,Nck1,Tnip3,Tagap,Notch2,Stxbp3,Mefv,Il12b,Cgas,Il1rn,Cd55,Ccdc88b,Cd14,Ednrb,Ifitm1,Bnip3,Ikbke,Serpina3f,Batf2,Arg2,Ptafr,Oas1a,Cxcl10,Tmem229b,Raet1e,Klrk1,Ifit3b,Gbp3,Stat2,Lcn2,Fpr2,Bcl2l11,Hck,Peli1,H2-Ab1,Smpdl3b,Treml4,Ddx58,Adar,Il12rb1,Tarm1,Cxcl3,Trib1,Tnfaip3,Irf7,Nlrc4,Stat1,Jak2,Tlr6,Zbp1,Nlrp3,Mndal,Zc3hav1,Tnfrsf1b,Optn,Plac8,Ifi211,Clec4n,Eif2ak2,Ccl7,Trim12a,Cxcl1,Ifna2,Iigp1,Apobec3,Slfn9,Herc6,Ifit3,Ddit4,Parp14,Batf,Oas3,Ccl2,Ppp1r14b,Nfkbia,Tlr9,Pf4,Evl,Psmb9,Fcgr1,Slamf8,Gbp2,Csf1,Tgtp1,Ifih1,Nr1h3,Ccl9,Oas1b,Rnf19b,Tent5a,Fcgr4,Fzd5,Ccl8,Ptgs2,Oasl2,Abr,Ifit2,Ifit1,Gbp2b,H2-Eb1,Cd80,Slpi,Ifit1bl1,Cd86,Isg20,Adgrl2,Plscr1,Spn,Pik3cd,Cxcl11,Trim30a,C1rl,Il4ra,Cav1,Lyn,Ifit1bl2,Acod1,Usp18,Cd274,Dhx58,Irf8,Axl,Lgals9,Trim13,Hp,Ier3,Ccl22,Ifi204,Ccl3,Tnf,Oasl1,Rsad2,Jun,Stxbp1,Ccl4,Syk,Rnf135,Ago3,Ccl12,Pml,Zyx,Noct,Rab20,Prdx1,Ly6a,Prdm1,Il27,Ccl5,Trim14,Serpinb9,Cxcl2,Nod1,Ifnb1,Cd40,Fgr,Mtdh,Gbp8,Ankrd17,Tlr1,Nt5c3,C3,Cd180,Junb,Gsdmd,Malt1,Oas2,Pde4b,Slfn4,Gbp4,Tab2,Nos2,Irgm2,Ifna4,Tifa,Parp9,Ripk2,Cxcl9,Tnfsf8,Stx11,Nmi,Casp1,Cmpk2,Cdc42ep2,Clec5a,Nfkbil1,Trim26,Casp4,Tlr2,Clec4d,Clec4e,Mx2,Mx1,Marco,Flnb,Nfkbib,Ifi44,Slfn2,Rgs1,Gfi1,Il18,Zc3h12a,Slamf7,Irak2,Aim2,Shfl,Gbp7,Ptger4,Mcoln2,Tnfsf4,Irf2,Il10,H60b,S100a8,Cx3cr1,Irf1,Cdc42ep4,H2-Q7,Tap2,Nod2,Serpine1,Resf1,Trim21,Stap1,Sp110,Ptgir,Ddx60,C1ra,Zfp36,Irf4,Irak3,Dtx3l |
| 2.456e-73 | -167.19 | GSE7348_UNSTIM_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE7348_UNSTIM_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN | 144 | 98 | 15632 | 1249 |
Casp1,Lipe,Psmb9,Itpr1,Dbnl,Mlkl,Mxd1,Marcksl1,Isg15,Calcrl,Smg7,Crlf3,Relb,Rgl1,Snx10,Ccnj,Nampt,Slc2a6,Inpp5b,Stx11,Hap1,Tyk2,Ptprj,Nfxl1,Il15ra,Adhfe1,Bbx,Tmem171,Samd9l,Kremen1,Pgs1,Pttg1,Cdc42ep2,Fbxo4,Slc28a2,Phf11c,Abtb2,Psmb8,Casp4,Plekha2,Ep400,Plscr1,Hivep3,Ccdc25,Dck,Dyrk2,Ifi35,Etnk1,Azi2,Irf1,Phf11d,Tnip1,Tmem67,Cflar,Zcchc2,Phf11b,Tpst1,Ubtd2,Cycs,Tlk2,Psmb10,Tnfaip3,Golga3,Ppp1r15a,Lcp2,Parp12,Sh3bp4,Il12rb1,Mmp13,Ripk2,Pcgf5,Fam53c,Atp10a,Map3k8,Arid5b,Cox18,Ppp2r2a,Sp110,Ptges,Sod2,Eif2ak2,Lrch1,Ggct,Usp25,Fas,Ddx60,Arl4a,Phf11a,Il15,Zc3hav1,Rnf14,Nfkb1,Zeb1,Usp12,Mtdh,Max,Mppe1,Dusp16 |
| 3.688e-73 | -166.78 | GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_UP | 167 | 105 | 15632 | 1249 |
Pdpn,Nfkbia,Pik3r5,Cdc42ep2,Flnb,Slc39a14,Met,Hcls1,Pfkl,Prkar2b,Ell2,Denr,Ier3,Mefv,Gpd2,Sema4a,Gsr,Src,N4bp1,Cd40,Slc2a1,Hck,Marcksl1,Malt1,Slco3a1,Jmjd6,Traf1,Antxr1,Csf3,Tmem26,Hk2,Slc13a3,Slc31a2,Samsn1,Myo1b,Pik3r6,Il1rn,Igf2bp2,Dcbld2,Gng12,Traf3ip2,Zc3h12a,Tgfbi,Kcna3,Il12b,Fcgr2b,Mmp14,Mllt6,Vcan,Ift57,Scarf1,Spn,Gadd45b,Aoah,Rapgef5,Sod2,Ppp1r14b,Gpr18,Spic,Mrpl52,Sdc4,Lpcat2,Klf7,Ahr,Me1,Fas,Tpi1,Pgm1,Rtn2,Kctd12,Nfkb1,Ednrb,Pid1,Nos2,Lmo4,Clcn7,Lrrc25,Dusp16,Ppfibp2,Abcc1,Nfil3,Lrrc8c,Sema4c,Dram1,Dgkh,Itga5,C3,Dtx2,Rab20,Micall2,Cp,Rab11fip1,Nfkbie,Tnf,Cd302,Myd88,Etv5,Irak3,Ch25h,Slc39a13,Rapgef2,Vasp,Pde4b,Ccl5,Gpr85 |
| 4.555e-73 | -166.57 | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | 188 | 111 | 15632 | 1249 |
Ifi207,Phf11a,Slamf7,Ifi214,Rtp4,Ddx60,Scarf1,Stap1,Dnaja1,Ets2,Gadd45b,Eif2ak2,Ccl4,Ifit3b,Parp11,Ifi204,Oasl1,Dram1,Xaf1,Tdrd7,Trim21,Isg20,Trim14,Ifi211,Lap3,Mndal,Sema3c,Cd38,Batf,Ifih1,Usp18,Aim2,Ch25h,Dhx58,Rsad2,Ifi44,Ifi209,Bcl6,Oas3,Tnf,Ifit2,Phf11b,Sp110,Gtpbp2,Arid5b,Ripk2,Tlr3,Parp12,Rapgef2,Inhba,Trim26,Irf7,Tap2,Phf11c,Tap1,Adar,Zbp1,Atf3,Il6,Kcnj2,Agrn,Ifit1bl1,Zcchc2,Cflar,Phf11d,Aida,Irf1,Socs3,Stat1,Ifi35,Ifi203,Oas1a,Plscr1,Casp4,Ifit3,Lnpep,Psmb8,Cd164,Isg15,Traf1,Trim12c,Socs1,Stat2,Ddx58,Pml,Hlx,Tank,Ifi205,Psmb9,N4bp1,Sp140,Src,Ifi213,Trafd1,Il15ra,Tnfsf10,Il1rn,Ak4,Mob3b,Kcna3,Oas1g,Dusp5,Traf3ip2,Herc6,Oas2,Ifi208,Slc2a6,Nmi,Ube2l6,Cnp,Ifit1bl2 |
| 5.179e-73 | -166.44 | GSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN | MSigDB lists | GSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN | 199 | 114 | 15632 | 1249 |
Irgm2,Irf4,Peli1,Znfx1,Pnpt1,Rbm43,Zbp1,Samhd1,Tap1,Nfkbiz,Phip,Rnf19a,Oas1a,Ccrl2,Birc3,Ifit3,Gbp7,Ogfr,Sh3bgrl2,Rgs1,Etnk1,Ifi35,Socs3,Stat1,Ppa1,Aida,Irf1,Slc25a22,Fam111a,Gbp4,Cish,Tapbp,Apobec3,Insl6,Psmb9,Ifit1,Daxx,Gbp2,Irf2,Pml,Stat2,St3gal6,Isg15,Socs1,Noc4l,Oas2,Nampt,Gch1,Cnp,Lgals9,Slfn3,Slfn9,Clic4,Tnfsf10,Trafd1,Cmpk2,Rnf19b,Oas1g,Grina,Cxcl10,Parp14,Tor1aip2,Slfn8,Gadd45g,Parp9,Morc3,Rnf114,Tmem184b,Slc16a1,Rbl1,Fas,Usp25,Rtp4,Isg20,Trim21,Syne2,Tdrd7,Tor3a,Mov10,Lmo4,Gem,Casp8,Arf4,Cd82,Oasl1,Pim2,Asb13,Ifit3b,Stat3,Gbp9,Rsad2,Dhx58,Ifit2,Txnrd1,Arid5a,Sgk3,Batf,Myd88,1600014C10Rik,Stau1,Usp18,Zfp281,Ifih1,Gbp3,Trim26,Parp12,Tor1aip1,Slfn4,Cd274,Vps54,Irf7,Mitd1,Tlr3,Map3k8 |
| 1.475e-72 | -165.40 | response to biotic stimulus | biological process | GO:0009607 | 1216 | 269 | 20694 | 1406 |
Rsad2,Jun,Ifi204,Ccl3,Tnf,Oasl1,Syk,Rnf135,Stxbp1,Ccl4,Pml,Zyx,Ago3,Ccl12,Prdx1,Prdm1,Ly6a,Il27,Noct,Rab20,Ifnb1,Nod1,Ccl5,Trim14,Serpinb9,Cxcl2,Cd40,Fgr,Mtdh,Gbp8,Ankrd17,C3,Cd180,Tlr1,Nt5c3,Oas2,Pde4b,Junb,Gsdmd,Malt1,Ifit2,Abr,Oasl2,Ptgs2,Slpi,Cd80,Ifit1bl1,H2-Eb1,Ifit1,Gbp2b,Isg20,Adgrl2,Cd86,Spn,Pik3cd,Plscr1,Il4ra,Cav1,Lyn,Trim30a,Cxcl11,C1rl,Usp18,Ifit1bl2,Acod1,Irf8,Axl,Lgals9,Hp,Trim13,Cd274,Dhx58,Ccl22,Ier3,Shfl,Aim2,Ptger4,Mcoln2,Gbp7,H60b,Il10,Cx3cr1,S100a8,Tnfsf4,Ppp1r15b,Irf2,Irf1,Cdc42ep4,Nod2,Serpine1,Tap2,H2-Q7,Sp110,Resf1,Trim21,Stap1,Ddx60,C1ra,Ptgir,Dtx3l,Irak3,Zfp36,Irf4,Irgm2,Ifna4,Tifa,Ripk2,Parp9,Slfn4,Gbp4,Tab2,Nos2,Cxcl9,Casp1,Cmpk2,Stx11,Tnfsf8,Nmi,Nfkbil1,Trim26,Casp4,Cdc42ep2,Clec5a,Mx2,Tlr2,Clec4d,Clec4e,Flnb,Nfkbib,Mx1,Marco,Rgs1,Gfi1,Ifi44,Slfn2,Irak2,Il18,Zc3h12a,Slamf7,Cx3cl1,Mt2,H2-Aa,Nlrc5,Gbp9,Plaat3,Trim56,Fcgr2b,Gch1,Arid5a,AA467197,Ifna6,Nck1,Myd88,Irgm1,Notch2,Tnip3,Tagap,Stxbp3,Cd55,Ccdc88b,Mefv,Il12b,Cgas,Il1rn,Ifitm1,Bnip3,Cd14,Ednrb,Cflar,Ciita,Saa3,Il6,G3bp2,Samhd1,Bmp2,Slfn8,Trem1,Oas1g,Nfkb1,Tnfrsf14,Prkce,Tlr3,Ifi205,Ifnar1,Itgav,Rtp4,Mapkapk2,Isg15,Il1b,Trim34a,Acp5,Ifna1,Cxcl1,Trim12a,Ccl7,Eif2ak2,Herc6,Ifna2,Iigp1,Apobec3,Slfn9,Parp14,Ddit4,Ifit3,Tlr9,Pf4,Nfkbia,Psmb9,Evl,Fcgr1,Slamf8,Gbp2,Batf,Ccl2,Oas3,Ppp1r14b,Csf1,Tgtp1,Ifih1,Rnf19b,Nr1h3,Ccl9,Oas1b,Ccl8,Tent5a,Fcgr4,Fzd5,Ikbke,Batf2,Serpina3f,Raet1e,Klrk1,Arg2,Ptafr,Cxcl10,Oas1a,Tmem229b,Stat2,Lcn2,Fpr2,Ifit3b,Gbp3,Smpdl3b,Treml4,Hck,Bcl2l11,Peli1,H2-Ab1,Il12rb1,Tarm1,Cxcl3,Tnfaip3,Irf7,Trib1,Ddx58,Adar,Zbp1,Nlrc4,Stat1,Tlr6,Jak2,Zc3hav1,Nlrp3,Mndal,Plac8,Optn,Clec4n,Ifi211,Tnfrsf1b |
| 6.208e-72 | -163.96 | response to stress | biological process | GO:0006950 | 2948 | 454 | 20694 | 1406 |
Zfp36,Enpp4,Trim21,Sp110,Igtp,H2-Q7,Serpine1,Nod2,Pla2g7,Nfkbid,Plau,Cdc42ep4,Hdac1,Acvr1,Hinfp,Tnfsf4,S100a8,Mcoln2,Atp2b4,Ptger4,Aim2,Adora2a,Shfl,Egln3,Slamf7,Irak2,Gm4841,Notch1,Uaca,Flnb,Clec4e,Clec4d,Hmox1,Tlr2,Themis2,Mx2,Asns,Dyrk2,Cdc42ep2,Map4k4,Ptprj,Nmi,Tlk2,Tnfsf8,Stx11,Ass1,Cxcl9,1600014C10Rik,Wdr59,Smc5,Gbp4,Nos2,Parp9,Irgm2,Ifna4,Sesn3,Gsdmd,Malt1,Fpr1,Pde4b,Oas2,Tlr1,C3,Cd74,Nox1,F830016B08Rik,Vrk2,Fgr,Ankrd17,Larp1,Psip1,Ccl5,Trim14,Cxcl2,Serpinb9,Nod1,Cdkn2d,Ifnb1,Rab20,Prdm1,Eya4,Zyx,Pml,Ccr1,Ccl4,Stat4,Syk,Oasl1,Ifi204,Ccl3,Sod2,Ier3,Dhx58,Tap1,Txnrd1,Hp,Trim13,Axl,Irf8,Slc39a4,Ifit1bl2,C1rl,Sdc1,Lyn,Tnip1,Il4ra,Slc7a11,Fam129a,Tank,Hspa1b,Timeless,Cd38,Isg20,Higd1a,Gbp2b,Ifit1,Atm,Ifit1bl1,Fos,Olr1,Bcl2a1d,Myc,Kmo,Clec2d,Ccl9,Oas1b,Rnf19b,Ccrl2,Birc2,Tgtp1,Ifih1,Klf2,Fcgr1,Slc9a1,Gbp2,Pf4,Tlr9,Apaf1,Ddit4,Dio2,Parp14,Iigp1,Mecp2,Vegfc,Ap3b1,Ccl7,Cxcl1,Trim12a,Optn,Mcm6,Stat1,Flrt3,Prdx5,Nlrc4,Adar,Mcm10,Ripk3,Trib1,Il12rb1,Cxcl3,Tarm1,H2-Ab1,Hck,Stat3,Src,Smpdl3b,Tnks1bp1,Gbp3,Tapbp,Lcn2,Tfec,Cxcl10,Ptafr,Dst,Ero1l,Ak4,Klrk1,Pdgfb,Ikbke,Batf2,Ppp1r15a,Bcl6,Mmp25,Il1rn,Cgas,Kdm6b,Rcan1,Ube2e2,Tagap,Egr1,Rgcc,Notch2,Irgm1,Myd88,Serp1,Dcbld2,Arid5a,Gch1,Fcgr2b,Kdr,Gbp9,Nlrc5,Ubash3b,Cx3cl1,Mdfic,Procr,Slc7a2,Mdm2,Hmga2,Pttg1,Mapkapk2,Itgav,Gja1,Rtp4,Casp3,Ikbkg,Hk2,Ccnd1,Nr4a3,Relb,Prnp,Trem1,Thbs1,Mt1,Slfn8,Samhd1,Rel,Hif1a,Il6,9930111J21Rik1,Kdm4a,Ciita,Cflar,Irf4,Gclm,Dtx3l,Tgtp2,Ccr3,Ptgir,C1ra,Ddx60,Serpinb2,Edn1,Dnaja1,Trip13,Fas,Hmga1,Papss2,Irf1,Ppp1r15b,Irf2,Map2k4,Cx3cr1,H60b,Asf1a,Il10,Cmklr1,Lnpk,Hspa1a,Gbp7,Tspo,Zc3h12a,Il18,Trip10,Sele,Mx1,Marco,Clec5a,Casp4,Trim26,Ldlr,Il18rap,Casp1,Traf2,Nek6,Tifa,Ripk2,Mul1,Nqo1,Nt5c3,Gclc,Parp3,Cd180,Gbp8,Cd40,Icam1,Hk1,Uchl1,Prdx1,Il27,Rasgrp1,Ccl12,Parp10,Atf3,Stxbp1,Rnf135,Cited2,Tnf,Plk3,Mapkbp1,Daxx,Il1a,Fam162a,Rcsd1,Jun,Rsad2,Slc2a1,Mmp9,Sirt1,Ccl22,Itpr1,Acod1,Sqstm1,Trim30a,Cxcl11,Spire1,Cav1,Osm,Plscr1,Pik3cd,Hsph1,Spn,Cd86,Marf1,F10,H2-Eb1,Slpi,Ptgs2,Bcl9,Ifit2,Oasl2,Pdgfrb,Ccl8,Gm12185,Ptk2,Hspa2,Ifrd1,Nupr1,Csf1,Gsr,Dnajb2,Ccl2,Batf,Oas3,Ppp1r14b,Slamf8,Slc30a1,Adrb2,Evl,Ifit3,Rnf34,Apobec3,Rbpms,Plekhn1,Slfn9,Ifna2,Tnc,Gm4951,Herc6,Pdpn,Pnpt1,Eif2ak2,Map3k8,Ascc3,Stat5a,Tnfrsf1b,Rnf139,Plac8,Clec4n,Ifi47,Nlrp3,Zc3hav1,Rgs14,Lrp11,Timp1,Tlr6,Jak2,Errfi1,Sphk1,Zbp1,Susd6,Ddx58,Vasn,Pgk1,Tnfaip3,Irf7,Bcl2l11,Bcl2a1a,Treml4,Pdk3,Map2k1,Ifit3b,Fpr2,Stat2,Oas1a,Flt1,Arg2,Raet1e,Dnaja2,Ednrb,Cd14,Ifitm1,Bnip3,Il12b,Mefv,Ccdc88b,Cd55,Stxbp3,Tmem67,Acvrl1,Ifna6,Nck1,Etv5,Sdc4,Abcc1,Uba7,Cdkn1a,Trim56,Rbbp8,Nampt,Gm5431,Srxn1,Bcl2a1b,H2-Aa,Mt2,P2ry12,Ifna1,Acp5,Trim34a,Btg2,Mlkl,Lrrc8c,Il1b,Isg15,Trib3,Pmaip1,Ifnar1,Plat,Nfkbiz,Tlr3,Prkce,Tnfrsf14,Oas1g,Nfkb1,Plek,Cpeb4,Bmp2,Casp2,Zbtb5,G3bp2,Cnn2,Saa3,Lox,Mcm9 |
| 3.284e-71 | -162.29 | GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN | MSigDB lists | GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN | 152 | 99 | 15632 | 1249 |
Ppfibp1,Nlrp3,Dtwd1,Trim13,Mapkapk2,Abr,Nfkbiz,Samd9l,Igsf6,Edn1,Psmd10,Pik3r5,Sbds,Tmem200b,Flrt3,Adhfe1,Nfkbia,Agpat4,Tnfaip2,Fam20c,Gpd2,Mefv,Irf1,Hivep3,Ccrl2,Plscr1,Casp4,Heatr6,Abtb2,Relb,Hck,Gbp2,Nod1,Crlf3,Traf1,Icam1,Nfkbil1,Malt1,Rffl,Tank,Dse,Ehd1,Plaur,Ptafr,Il12b,Ptgs2,Kcna3,Dnaja2,Ptger4,Rnf19b,Tnfsf15,Btg2,Pik3r6,Samsn1,Gch1,Rgl1,Slc4a7,Olr1,Ahr,Klf7,Nck1,Ift57,Fcgr2b,Sqstm1,Frmd6,Dusp16,Ccl4,Gbp2b,Notch2,Fam102b,Rhou,Lmo4,Rel,Rnf14,Nfkb1,Mvp,Cd38,Cd14,Ube2f,Ccdc88b,Myd88,Rnd1,Nupr1,Mcoln2,Rsad2,Cers6,Dock10,Nfkbie,Rhbdf2,Irak2,Ralgds,St3gal1,Rapgef2,Rrs1,Med21,Cd274,Ccl5,Pde4b,Plek |
| 1.642e-70 | -160.68 | GSE17721_0.5H_VS_4H_CPG_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_CPG_BMDC_DN | 181 | 107 | 15632 | 1249 |
Jak2,Ppfibp2,Dusp16,Itga5,Cpeb4,Mtdh,Asb13,Csf1,Isg20,Syne2,Stx6,Ppp1r15b,Nfkb1,Tor3a,Lmo4,Nos2,Lap3,Rel,Il15,F10,Pilra,Sgcb,Rbl1,Dusp14,Me1,Aff1,Enpp4,Stxbp1,Rtp4,Kat2b,Aftph,Nat2,Tor1aip2,Itgav,Crbn,Ets2,B4galt4,Mitd1,Ikbke,Ptges,Ppp2r2a,Pkp4,Rtn1,Atp10a,Fam53c,Gpr85,Il18,Nrp2,Reps1,Rab10,Trim26,Tbc1d13,Ccl5,Golga3,Pdgfrb,Plagl2,Rab3ip,Nupr1,Aim2,F11r,Upp1,Tnfsf8,Cp,Ythdf1,Mafk,Slc25a37,Arhgef3,Asf1a,Cacna1d,Gfi1,Kif5c,Ell2,Mtmr14,Ifi35,Gpd2,Bcl9,Slc39a14,Rnf19a,Jag1,Birc3,Eno2,Gbp7,Tap1,Slc28a2,Mapkapk2,Nlrp3,Stard5,Edn1,Irgm2,Tra2a,Gca,Tnfsf10,Igf2bp2,Fndc3a,Rnf19b,Fpr1,Caml,Uba7,Ccnj,Mthfr,Magohb,Icam1,Calcrl,Slc15a3,Rffl,Tbc1d1,Tank |
| 1.454e-69 | -158.50 | GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN | MSigDB lists | GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN | 156 | 99 | 15632 | 1249 |
Map2k4,Asb13,H3f3b,Whamm,Fam102b,Arf4,Rap2c,Rnf14,Usp12,Tdrd7,Xaf1,Alas1,Dcp2,Kat2b,Aldh1b1,Fas,Usp25,Zc3hav1,Slamf7,Morc3,Scarf1,Aftph,Mmp14,Cox18,Xkr8,Atp10a,Tlr3,Fam53c,Pcgf5,Ptges,Keap1,Sp110,Gtpbp2,Cd274,Osm,Golga3,Brwd3,Upp1,Ifih1,Aim2,Cd38,Myd88,Traf5,Sav1,Tpst1,Tlk2,Cers6,Cycs,Stat3,Aida,Azi2,Acsl1,Gpd2,Tmod3,Ppa1,Tmem219,Tmem67,Gna15,Plekha2,Casp4,Mier3,P4ha1,Smpdl3b,Zc3h7a,Pttg1,Mapkapk2,Samhd1,Hinfp,Rbm43,Pnpt1,Nlrc5,Samd9l,Triobp,Tmem171,Ikzf1,Peli1,Bbx,Mob3b,Cxcl10,Nsmaf,Fmnl2,Cmklr1,Pik3r6,Nampt,Ccnj,Gch1,Hap1,Isg15,Irf2,Mxd1,Mcm10,Crlf3,Nod1,Smg7,Psmb9,Casp1,Mlkl,Pnp2,Dbnl |
| 2.937e-69 | -157.80 | GSE19888_ADENOSINE_A3R_INH_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP | 181 | 106 | 15632 | 1249 |
Ch25h,Usp18,Gbp3,Psmb10,Ifih1,Sgk3,Mvp,Ifit2,Batf2,Ifi44,Gbp9,Tlk2,B3gnt5,Rsad2,Dhx58,Tlr3,Pcgf5,Usp42,Mitd1,Inpp1,Sp110,Cd274,Parp12,Dcp2,Rtp4,Zc3hav1,Slfn5,Rnf114,Slfn8,Tor1aip2,Parp14,Parp9,Parp11,Mthfd2,Ifit3b,Ddx4,Asb13,Jak2,Atm,Trim21,Psme2,Trim56,Xaf1,Psme1,Mthfr,Pml,Ddx58,Stat2,Trim12c,Traf1,Dtx3l,Isg15,Daxx,Ifit1,Gbp2,Insl6,Psmb9,Cd40,Setdb2,Gbp4,Tapbp,Herc6,Oas1g,Kcna3,Cxcl10,Serpinb9,Fpr1,Tnfsf10,Slfn9,Prkx,Clic4,Cmpk2,Ifit1bl2,Ppm1k,Ube2l6,Nmi,Oas2,Uba7,Tmtc2,Prnp,Hinfp,Zbp1,Rbm43,Adar,Tap1,Samhd1,Ifit1bl1,Nlrc5,Agrn,Irgm2,Il18bp,Samd9l,Ifi35,Etnk1,Stat1,Dck,Irf1,Zcchc2,Tnfaip2,Psmb8,Ifit3,Casp4,Gbp7,Zc3h7a,Timeless,Oas1a |
| 6.506e-69 | -157.01 | GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP | MSigDB lists | GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP | 151 | 97 | 15632 | 1249 |
Slc7a2,Daam1,Samsn1,Gch1,Ifit1bl2,Ccnj,Snx10,Junb,Oas2,Cxcl10,Mob3b,Zc3h12a,Cmpk2,Osbpl3,Il1rn,Cd40,Slc2a1,Ttc39c,Ehd1,Dusp1,Stk40,Mdm2,Gbp4,Rffl,Slco3a1,Socs1,Calcrl,Stat2,Hif1a,Ddx58,Gbp2,Hck,Heatr6,Zc3h12c,Met,Cd69,Rasgrp1,Ccrl2,Acsl1,Mafg,Gpd2,Ier3,Acvr1b,Stat1,Denr,Kpna3,Pfkl,Tmem123,Zcchc2,Cflar,Zyx,Flrt3,Ifit1bl1,Adhfe1,Hivep2,Peli1,Gpr35,Edn1,Nlrp3,Atf3,Tap1,Zbp1,Irf7,Brd2,Myadm,Parp12,Cxcl2,Mmp13,Reps1,Sap30,Cxcl1,Vcam1,Ifit2,Rsad2,Cers6,Errfi1,Gbp9,Gbp3,Prpf38a,Rab3ip,Batf,Nfkb1,Nfkbib,Zfp36,Atxn7l1,Rab20,Dtx2,Dusp16,Gbp2b,Parp14,Bnip3,Tor1aip2,Rtp4,Ddx60,Slfn5,Klf7,Il27 |
| 1.133e-68 | -156.45 | GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_UP | MSigDB lists | GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_UP | 190 | 108 | 15632 | 1249 |
Nfkbiz,Abr,Ccnd2,Il4ra,Pfkfb3,Msr1,Cyfip1,Pdpn,Ccl2,Peli1,Kpna3,Mtmr14,Socs3,Acsl1,Tnfaip2,Birc3,Il10,Lcn2,Gbp7,Procr,Marcksl1,Slc30a4,Ier2,Icam1,Hif1a,Il1a,Calcrl,Socs1,Clcn5,Relb,Ehd1,Ifnar1,N4bp1,Hspa1a,Tank,Rhoq,Mdm2,Cebpd,Stk40,Psma6,Bcl2a1d,Rnf19b,Fndc3a,Pim1,Ptgs2,Clec4d,Bcl2a1a,Il1rn,Serpinb2,Plaur,Junb,Snx10,Gch1,Map4k4,Hk2,Nek6,Il15,Tle3,Gadd45b,Klf3,Bcl2a1b,Mrpl52,Pla2g4a,Mmp14,Dusp2,Ifrd1,Mtdh,Lpar1,Map2k4,Notch2,Znrf1,Jak2,Tax1bp1,Dusp16,Cdkn1a,Ppp1r15b,Nfkb1,Cav1,Nfkbib,Kctd12,Mcoln2,Nupr1,Upp1,Tab2,Cd14,Apaf1,Stat5a,Txnrd1,Arhgef3,Slc39a4,Errfi1,Glipr2,Aebp2,Crkl,Slc31a1,Map3k8,Cxcl1,Plat,Ptges,Il1b,Myadm,Gja1,Lcp2,Serpine1,Ext1,Rab10,Mmp13,Vasp |
| 1.133e-68 | -156.45 | GSE33424_CD161_INT_VS_NEG_CD8_TCELL_UP | MSigDB lists | GSE33424_CD161_INT_VS_NEG_CD8_TCELL_UP | 190 | 108 | 15632 | 1249 |
Oas2,Hap1,Nmi,Rilpl1,Cd86,Ppm1k,Nampt,Ifit1bl2,Cmpk2,Trafd1,Tnfsf10,Slfn9,Slfn3,Cxcl10,Oas1g,Herc6,Larp1,Tapbp,Setdb2,Gbp4,Mdn1,Gypc,N4bp1,Gbp2,Hck,Daxx,Ifit1,Trim12c,St3gal6,Isg15,Dtx3l,Ddx58,Stat2,Pml,Cd69,Oas1a,Ccrl2,Gbp7,Casp4,Ifit3,Cd300lf,Zcchc2,Irf1,Ppa1,Stat1,Ifi35,Samd9l,Bbx,Peli1,Abcb1a,Irgm2,Agrn,Nlrc5,Ifit1bl1,Samhd1,Zbp1,Pnpt1,Pfkfb3,Nmral1,Ccnd2,Parp12,Pde7b,Slc25a12,Il12rb1,Irf7,Slfn4,Cd274,Asns,Epsti1,Mitd1,Inpp1,Cox18,Tlr3,Rsad2,Dhx58,Gbp9,Ifi44,Oas3,Tpst1,Ifit2,Ncoa7,1600014C10Rik,Ifih1,Usp18,Tdrd7,Etv6,Xaf1,Csf1,Trim21,Isg20,Lap3,Tor3a,Pmepa1,Ifit3b,Asb13,Parp11,Oasl1,Parp9,Slfn8,Parp14,Tor1aip2,Eif2ak2,Plac8,Rbl1,Slfn5,Sgcb,Rtp4,Ddx60 |
| 2.417e-68 | -155.69 | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN | MSigDB lists | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN | 191 | 108 | 15632 | 1249 |
Il4ra,Ccnd2,Nfkbiz,Msr1,Cyfip1,Ccl2,Pdpn,Peli1,Myc,Acsl1,Socs3,Kpna3,Mtmr14,Stard7,Tnfaip2,Gbp7,Lcn2,Il10,Birc3,Procr,Socs1,Hif1a,Icam1,Spata13,Il1a,Marcksl1,Slc30a4,Ier2,Relb,Clcn5,Tank,Cd40,Ifnar1,N4bp1,Dusp1,Ehd1,Cebpd,Stk40,Bcl2a1d,Psma6,Mdm2,Rhoq,Clec4d,Pim1,Ptgs2,Fndc3a,Rnf19b,Plaur,Serpinb2,Bcl2a1a,Il1rn,Gch1,Map4k4,Junb,Jarid2,Snx10,Hk2,Inpp5b,Nek6,Tle3,Clec4e,Il15,Ets2,Mrpl52,Bcl2a1b,Klf3,Cpd,Ifrd1,Mmp14,Pla2g4a,Fcgr2b,Map2k4,Rnf145,Lpar1,Mtdh,Cdkn1a,Dusp16,Tax1bp1,Jak2,Znrf1,Nfkb1,Nfkbib,Zeb1,Mcoln2,Nupr1,Apaf1,Cd14,Myd88,Txnrd1,Stat5a,Glipr2,Errfi1,Stat3,Map3k8,Slc31a1,Crkl,Ptges,Il1b,Stip1,Nfkb2,Cxcl1,Serpine1,Lcp2,Myadm,Vasp,Mmp13,Ext1,Rab10 |
| 3.959e-68 | -155.20 | GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_DN | 170 | 102 | 15632 | 1249 |
Dgkh,Dram1,Mtdh,Cpeb4,Itga5,Trib1,Tnip3,Dcun1d3,Tnfrsf1b,Lmo4,Tdrd7,Ddx60,Nck1,F10,Gadd45b,Spn,Gramd1a,Gpr18,Trip10,Dusp2,Xkr8,St3gal1,Ripk2,Usp42,Gpr85,Il18,Gtpbp2,Ralgds,Cldnd1,Stip1,Hsd17b12,Cd274,Map2k1,Serpine1,Cxcl2,Prdm1,Gbp3,Psmb10,Ccdc88b,Cd14,Mvp,Tnfaip3,Plagl2,Prpf38a,Ddhd1,Slc16a3,Traf2,Cp,Batf2,Itgb8,Nfkbie,Aebp2,Casp7,Denr,Tnfaip2,Kdr,Tmem123,Tagap,Mier3,Abtb2,Marco,Itgal,Lcn2,Procr,Bcorl1,Pdss1,Slc39a14,Rnf19a,St3gal3,Rras2,Agrn,Pik3r5,Ikzf1,Stard5,Kremen1,Ncoa5,Rnf19b,Clec4d,Il12b,Acsl5,Osbpl3,Gca,Fmnl2,Zhx2,Nampt,Rgl1,Tshz1,Samsn1,Slc7a2,Tlr1,Tnfsf15,Stx11,Hif1a,Spata13,Socs1,Nod1,Relb,N4bp1,Birc2,Dusp8,Egr2,Lztfl1 |
| 3.897e-67 | -152.91 | HALLMARK_INFLAMMATORY_RESPONSE | MSigDB lists | HALLMARK_INFLAMMATORY_RESPONSE | 191 | 107 | 15632 | 1249 |
Cd14,Itgb8,Sele,Klf6,Csf3r,Irak2,Pcdh7,Il1b,Slc31a1,Ripk2,Tlr3,Il18,Adora2b,Gpr132,Icosl,Inhba,Ccl5,Pde4b,Serpine1,Osm,Irf7,Fzd5,Lcp2,Il15,Ahr,Olr1,Cx3cl1,Rtp4,Mmp14,Scarf1,Eif2ak2,Ldlr,Cd82,Cdkn1a,Ptgir,Itga5,Lyn,Lpar1,Csf1,Il18rap,Nfkb1,Tnfrsf1b,Lif,Mxd1,Sphk1,Sell,Calcrl,Il1a,Icam1,Hif1a,Tapbp,Ifnar1,Axl,Cd40,Timp1,Tnfsf10,Cmklr1,Plaur,Il15ra,Dcbld2,Cd55,Ptger4,Fpr1,Ptafr,Il12b,Cxcl10,Kcna3,Clec5a,Tnfsf15,Scn1b,Nmi,Tlr1,Btg2,Csf3,Gch1,Slc31a2,Nampt,Slc7a2,Slc28a2,Il4ra,Nlrp3,Sgms2,Ccl22,Il6,Pdpn,Myc,Edn1,Kcnj2,Nod2,Pik3r5,Ccl12,Nfkbia,Msr1,Rgs1,Ebi3,Mefv,Tlr2,Irf1,Acvr1b,Met,Cd69,Rasgrp1,Ccrl2,P2ry2,Gna15,Marco,Il10 |
| 5.150e-67 | -152.63 | regulation of response to external stimulus | biological process | GO:0032101 | 922 | 223 | 20694 | 1406 |
Clec2d,Nr1h3,Pde5a,Pdgfrb,Ptpn2,A530064D06Rik,Csf1,Nupr1,Il15,Ifih1,D1Ertd622e,Parp14,Trafd1,Fcgr1,Slamf8,Nfkbia,Tlr9,Adrb2,Ccl2,Stat5a,Cxcl1,Pdpn,Hopx,Socs1,Vegfc,Apobec3,Socs3,Zc3hav1,Mndal,Nlrp3,Optn,Ifi211,Dnase1l3,Swap70,Tnfrsf1b,Trib1,Tnfaip3,Irf7,Il12rb1,Tarm1,Rictor,Adar,Ddx58,Cd200,Sphk1,Zbp1,Stat1,Tlr6,Jak2,Nlrc4,Fpr2,Trim12c,Map2k1,Sema3c,Smpdl3b,Treml4,Peli1,Lpar1,Ikbke,Raet1e,Pdgfb,Klrk1,Cxcl10,Arg2,Cst7,Agrn,Il12b,Traf3ip2,Cgas,Mefv,Bcl6,Fabp7,Ifi214,Ednrb,Cd14,Calcrl,Tnip3,Cxcl14,Siglece,Cdkn1a,Pla2g4a,Fcgr2b,Irgm1,Myd88,Met,P2ry12,Cx3cl1,Nlrc5,Ubash3b,Kdr,Mapkapk2,Il1b,Slc7a2,Ifna1,Acp5,Nfkb1,Tnfsf14,Prkce,Ifi205,Nfkbiz,Tlr3,Gja1,Sema4a,Ctsc,Samhd1,Thbs1,Cd34,Cacnb3,Plek,Il6,Dusp1,Ddx60,Nectin2,Enpp4,Dtx3l,Irak3,Irf4,Ctla2a,Zfp36,Serpine1,Pla2g7,Nod2,Lrp8,Tap2,Stap1,Edn1,Elmod2,Sema4c,S100a8,Cx3cr1,H60b,Il10,Tnfsf4,Plau,Irf1,Aim2,Adora2a,Ptger4,Cmklr1,Bst1,Gfi1,Scarf1,Notch1,Cd300lf,Irak2,Zc3h12a,Fgl2,Clec4e,Gpr18,B430306N03Rik,Tlr2,Uaca,Ifi203,Pvr,Casp1,Ptprj,Nmi,Ldlr,Il18rap,Aoah,Nfkbil1,Mtus1,Tifa,Ripk2,Mul1,Ifi208,Parp9,Irgm2,Gbp4,Nos2,Wdfy1,Htra1,C3,Cd74,Cd180,Tlr1,Cd200r4,Treml2,Nod1,Ccl5,Serpinb9,Rabgef1,Fgr,Ankrd17,Igf1r,Pml,Ccr1,Rasgrp1,Ccl12,Prdm1,Il27,Rsad2,Mapkbp1,Tnf,Zswim4,Ccl3,Ifi204,Rnf135,Syk,Ccl4,Lgals9,Pik3r6,Dhx58,Tap1,Ier3,Sell,Cav1,Lyn,Tnip1,Osm,Kremen1,Trim30a,Ifi209,Clcf1,Usp18,Acod1,Adora2b,Cd86,Spn,Plscr1,Abr,Ptgs2,Atm |
| 1.277e-66 | -151.73 | GO_IMMUNE_SYSTEM_PROCESS | MSigDB lists | GO_IMMUNE_SYSTEM_PROCESS | 1741 | 349 | 15632 | 1249 |
Ppp1r14b,Itgav,Ptpn2,Nlrc4,Ctsc,Ifna5,Fas,Cx3cl1,Slamf7,Cd80,Clec4e,Il27,Ednrb,Tnfrsf1b,Nos2,Rel,Cav1,Ifi211,Trim14,Pou2f2,Rictor,Tlr9,Ifit3b,Cacnb3,Tnip3,Gbp2b,Ifit2,Ankrd17,Csf3r,Psmb10,Rnf135,Batf,Ccl3,Cd38,Ccr1,H2-Eb1,Cd274,Fzd5,Tap2,H2-Aa,Icosl,Psmb6,Hp,Nr4a3,Map3k8,Kitl,Ikbke,Cxcl1,Bcl2l11,Rab32,Nlrc5,Psmd10,Irf4,Irgm2,Cxcl14,Zbp1,Adar,Tap1,Tnfrsf14,Lnpep,Birc3,Casp4,Irf8,Itgal,Ifit3,Ifi203,Sirt1,Ifi35,Fam111a,Rgs1,Gfi1,Trem1,Tank,Cd40,Birc2,Pnp2,Ly75,Gbp4,Casp3,Psma6,Tapbp,Rhoh,Lif,Irf2,Trim12c,Isg15,Tnfrsf8,Myo10,Hck,Gbp2,Jarid2,Ifna6,Pdgfb,Oas2,Csf3,Zc3h12a,Rnf19b,Herc6,Cxcl10,Ptafr,Thbs1,Cmklr1,Elmod2,Ass1,Ifnb1,Ap3b1,Ddx60,Nck1,Ikbkg,Atm,Casp8,Sema3c,Slpi,Csf1,Trim21,Ptk2,Lyn,Ccl4,Nfil3,Gbp9,Rsad2,Treml2,Cd74,Cd14,Tnfaip3,Ccl5,Plek,Lcp2,Trim26,Il12rb1,Inhba,Crkl,Sec24a,Ccl12,Sbds,Cenpe,Cx3cr1,Jun,Tiparp,Tet2,Cyfip1,Ccl2,Il18bp,Tlr6,Mapkapk2,Il4ra,Prdx1,Rnf31,Clec4n,C1rl,Il10,Marco,Plscr1,Tmod3,Tnfsf4,Ebi3,Sema4a,Irf1,Cd300lf,Fam20c,Hcls1,Kdr,Cst7,Ifnar1,Axl,Dync1h1,Swap70,Dbnl,Pde1b,Pml,H2-Q7,Psme1,Hhex,Jmjd6,Nod1,Ripk3,Gch1,Junb,Slc7a8,Slc7a5,Ifi208,Tyk2,Clec4d,Clec5a,Prkx,Plcl2,Hcar2,Gsdmd,Cited2,Bnip3,Mid1,Cd34,Zc3hav1,Olr1,Lmo4,Zeb1,Isg20,Xaf1,Il18rap,Trim56,C3,Mmp9,Oasl1,Itga9,Ifi204,Notch2,Slc16a3,Oas3,Ifi209,Batf2,Tnfsf8,Aim2,Ifih1,Tab2,F11r,Pbx1,Myd88,Irak3,Ifna2,Irf7,Map2k1,Osm,Stxbp3,Ddit4,Bst1,Ripk2,Hmox1,Il18,Il1b,Flt1,Ifit1bl1,Prkce,Igsf6,Edn1,Nod2,Egr1,Nlrp3,Fcgr1,Ciita,Angpt1,Psmb8,Ampd3,Procr,Cysltr2,Rasgrp1,Oas1a,Jag1,Stat1,Mefv,Azi2,Pik3cd,Tnip1,Clcf1,Actb,Cd300e,Apobec3,Src,Malt1,Itga4,Ddx58,Cd180,Il1a,Hif1a,Stat2,Cd83,Relb,Notch1,Cd164,Ifit1,Arid4a,Slc7a2,Klf2,Oas1g,H2-Ab1,Ptger4,Tapbpl,Serpinb9,Pf4,Sec24b,Syk,Sqstm1,Eif2ak2,Spn,Fcgr2b,P2ry14,Ifi214,Ciapin1,Slc16a1,Il15,Ifi207,Nfkb1,S100a8,Gem,Mndal,Psme2,Etv6,Itga5,Jak2,Klf6,Tnf,Bcl6,H2-Q6,Dhx58,Sele,Fcgr4,Pde4b,Rrs1,Rab10,Cxcl2,Tlr3,Il2rg,Irak2,Nfkb2,Vcam1,Slc7a11,Nfkbia,H2-Q4,Il6,Abcb1a,Ikzf1,Ccl22,Trim13,Ifna1,Samhd1,Lcn2,Tnfsf14,Tlr2,Igf1r,Ifi213,Ifi205,Psmb9,Dennd1b,C1ra,Sell,Fgr,Icam1,Ifit1bl2,Snx10,Cd86,Tnfsf15,Tlr1,Traf3ip2,Kdm6b,Cd55,Ptprj,Kif3c,Il12b,Tnfsf10,Il1rn |
| 1.697e-66 | -151.44 | GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_DN | MSigDB lists | GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_DN | 193 | 107 | 15632 | 1249 |
Ifih1,Usp18,Ch25h,Olfml3,Gnb4,Ifit2,Rsad2,Treml2,Batf2,1110038F14Rik,Il2rg,Tlr3,Sp110,Inpp1,Irak2,Vcam1,Irf7,Tor1aip1,Cd274,AA467197,Il12rb1,Mmp13,Tpx2,Gmppb,Rtp4,Fpr2,Stxbp1,Ddx60,Slfn5,Slamf7,Sgcb,Il15,Gpr18,Plac8,Eif2ak2,Parp9,Ifnb1,Parp14,Tor1aip2,Slfn8,Ddx4,Parp11,Uaca,Arf4,Hdc,Nfkb1,Hk1,Tor3a,Etv6,Tdrd7,Slamf9,Trim21,Dtx3l,Trim12c,Stat2,Rhoh,Mxd1,Cd40,N4bp1,Tapbp,Setdb2,Serpinb9,Cxcl10,Slamf8,Oas1g,Larp1,Cmpk2,Lacc1,Prkx,Clic4,Slfn9,Cnp,Gch1,Ifit1bl2,Snx10,Uba7,Oas2,Stoml1,Nmi,Btg2,Slc28a2,Samhd1,Adar,Rbm43,Pik3r5,Ccl12,Nlrc5,Ifit1bl1,Samd9l,Cd200r4,Il18bp,Il6,Il4i1,Ikzf1,Tlr2,Irf1,Aida,Dck,Cd300lf,Tnfaip2,Rgs1,Gbp7,Itgal,Ccrl2,Oas1a,Timeless,Bcl9 |
| 1.811e-66 | -151.38 | ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION | MSigDB lists | ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION | 125 | 87 | 15632 | 1249 |
Oas2,Maff,Gch1,Junb,Ifit1bl2,Tfec,Cmpk2,Hcar2,Plaur,Thbs1,Bcl2a1a,Slfn3,Il1rn,Clec4d,Cxcl10,Cebpd,Bcl2a1d,Slc15a3,Gpr84,Timp1,Relb,Sell,Isg15,Il1a,Stat2,Mxd1,Marcksl1,Ccrl2,Pla2g7,Casp4,Clec4n,Tnfaip2,Tlr2,Mefv,Ms4a6d,Stat1,Socs3,Ebi3,Il4i1,Il6,Irgm2,Ccl12,Nfkbia,Ifit1bl1,Fcgr1,Pfkfb3,Nfkbiz,Atf3,Bst1,Sap30,Irf7,Serpine1,Lcp2,Slfn4,Plek,Ccr1,Il1b,Cxcl1,Map3k8,Rcan1,St3gal1,Fgl2,Oas3,Csf3r,Ifit2,Tnfaip3,Gda,Cd14,Sla,Arg2,Gbp3,Ifih1,Upp1,Usp18,Ch25h,Tifa,Gem,Nfil3,Adam19,Ccl4,Rab20,Gadd45g,Vcan,Bcl2a1b,Sod2,Clec4e,Il15 |
| 2.566e-66 | -151.03 | regulation of response to stimulus | biological process | GO:0048583 | 3734 | 515 | 20694 | 1406 |
Fam162a,Jun,Tcf4,Rsad2,Mapkbp1,Tnf,Daxx,Il1a,Rnf135,Cited2,Stxbp1,Bambi,Atf3,Rasgrp1,Ccl12,Acpp,Asah2,Il27,Prdx1,Angpt1,Uchl1,Icam1,Hk1,Mtdh,Nlgn2,Psd,Cd40,Rbl1,Parp3,Cd180,Gclc,Rpgrip1l,Cd200r4,Aida,Ksr1,Traf1,Ptgs2,Cyfip1,F10,Adora2b,Cd86,Rapgef2,Hsph1,Spn,Dusp5,Plscr1,Klf7,Cav1,Osm,Trim30a,Myadm,Spire1,Sqstm1,Itpr1,Acod1,Lgals9,Kctd12,Cd274,Plcl2,Ccl22,Sirt1,Mmp9,Plpp3,Cmklr1,Bst1,Cx3cr1,Il10,H60b,Ppp1r15b,Intu,Map2k4,Phlpp1,Irf1,Fas,Socs7,Dnaja1,Edn1,Elmod2,Cish,Sema4c,C1ra,Sgk3,Mmp14,Ddx60,Ptgir,Dtx3l,Gclm,Irf4,Lrp4,Tifa,Ripk2,Mul1,Hlx,Stk40,Rhbdf2,Rnf14,Wdfy1,Usp25,Traf2,Ifna5,Hap1,Ifi203,Pvr,Casp1,Jarid2,Ldlr,Rrs1,Il18rap,Casp4,Nfkbil1,H2-T22,Gpr18,Marco,Trip10,Gfi1,Scarf1,Tomm70a,Zc3h12a,Il18,Fgl2,P2ry12,Rffl,Arhgap26,Dusp6,Bcl2a1b,Sik3,Cdkn1a,Spata13,Casp8,Nampt,Pla2g4a,Ifna6,Nck1,Acvrl1,Gpr35,Tnfsf10,Tnip3,Mosmo,Tmem67,Cd55,Il12b,Agrn,Traf3ip2,Mefv,Bnip3,Ifi214,Ednrb,Samsn1,Cd14,Mid1,Lox,Acvr1b,Dusp1,Casp2,Bmp2,Plek,Tnfrsf14,Nfkb1,Cdk5r1,Prkce,Ifi205,Tlr3,Nfkbiz,H2-T10,Trib3,Pmaip1,Il1b,Sla,Pim3,Mlkl,Ifna1,Acp5,Map3k8,Stat5a,Pdpn,Socs1,Pnpt1,Eif2ak2,Eef1e1,Rnf34,Apobec3,Rbpms,Ifna2,Socs3,Birc3,H2-Q6,D1Ertd622e,Trafd1,Slamf8,Adrb2,Nfkbia,Ccl2,Mob3b,A530064D06Rik,Nupr1,Csf1,Il15,S1pr2,Sipa1l1,Ptk2,Prag1,Nr1h3,Tle3,Ccl8,Pdgfrb,Fzd5,Ptpn2,Tnfsf15,Gpc1,Raet1e,Lif,Usp12,Flt1,Arg2,Fpr2,Trim12c,Map2k1,Treml4,Nr3c1,Peli1,Bcl2l11,Bcl2a1a,Inhba,Irf7,Tnfaip3,Rictor,Ddx58,Traf5,Hmgn3,Dek,Vasn,Rap1gap2,Sphk1,Zbp1,Timp1,Lcp2,Tlr6,Jak2,Errfi1,Zc3hav1,Akt3,Rgs14,Nlrp3,Scimp,Ifi211,Clec4n,Tnfrsf1b,Sod2,Fzd1,Zswim4,Ifi204,Ccl3,Sh3bp4,Syk,Pde3b,Ccl4,Pml,Ccr1,Ago3,Eya4,Pim2,Pik3r5,Bfar,Prdm1,Ifnb1,Cdkn2d,Nod1,Ccl5,Rabgef1,Serpinb9,Vrk2,Fgr,Ankrd17,Map3k6,Igf1r,Phip,Nox1,Fignl2,C3,Cd74,Tlr1,Rnf31,Pde4b,Treml2,Malt1,Fpr1,Abr,Bcl2a1d,Atm,Higd1a,Arhgef3,Dusp2,Rgs3,Timeless,Cd38,Fam72a,H2-M2,Tank,Chst11,Lyn,Sell,Slc7a11,Ncoa7,Tnip1,Il4ra,Kremen1,C1rl,Ifi209,Clcf1,Usp18,Ptch1,Htr2b,Grina,Trim13,Axl,Acsl5,Pik3r6,Dhx58,Tap1,Hhex,H2-T24,Fam20c,Ier3,Aim2,Adora2a,Abcb1a,Atp2b4,Ptger4,S100a8,Plaur,Acvr1,Tnfsf4,Hdac1,Plau,Serpine1,Pla2g7,Nod2,Nfkbid,Radx,Lrp8,Tap2,H2-Q7,Tsku,Stap1,Homer1,Nectin2,Enpp4,Irak3,Gadd45g,Ctla2a,Zfp36,Cyth3,Ifi208,Parp9,Irgm2,Sesn3,Ifna4,Wdr59,Gbp4,Tab2,Nos2,Spred1,Htra1,Ptprj,Nmi,Aoah,Map4k4,Mtus1,Csf3,Gcnt2,Dyrk2,Icosl,Themis2,Clec4e,B430306N03Rik,Hmox1,Clec4d,Tlr2,Uaca,Pid1,Rgs1,Rhoh,Notch1,Cd300lf,Irak2,Itgal,Kitl,Cacna1d,Cx3cl1,Mdfic,Nlrc5,Ubash3b,Kdr,Siglece,Arid5a,Gch1,Fcgr2b,Irgm1,Myd88,Met,Calcrl,Notch2,Pmepa1,Egr1,Rgcc,Kmt5a,Fut8,Cxcl14,Cst7,Rcan1,Il1rn,Cgas,Txn1,Spred3,Gadd45b,Bcl6,Gdf15,Fabp7,Dusp4,Ppp1r15a,Cflar,Dusp8,Jag1,Il6,Hif1a,Sema4a,Samhd1,Ctsc,Thbs1,Plk2,Cd34,Grk3,Cacnb3,Prnp,Fbxo4,Psd4,Crlf3,Tnfsf14,Nr4a3,Psmd10,Itgav,Gja1,Ikbkg,Mapkapk2,Ppp2r3a,Hmga2,Mdm2,Slc7a2,Pdgfc,Glipr2,Cxcl1,Hopx,Card6,Ccl7,Ppp2r1b,Vegfc,Phactr4,Tulp3,Znrf3,Cenpj,Parp14,Ezr,Ddit4,Scyl2,Glrx,Fcgr1,Slc9a1,Pf4,Tlr9,Apaf1,Spry2,Dennd1b,Ifih1,Dusp16,Birc2,Ppp4r2,Clec2d,Zeb1,Ccl9,Phf11a,Myc,Pde5a,Htr2a,Fcgr4,Plagl2,Lpar1,Ikbke,Klrk1,Pdgfb,Cxcl10,Ptafr,Hcls1,Smpdl3b,Sema3c,Gpr68,H2-Ab1,Stat3,Src,Ncoa5,Trib1,Il12rb1,Tarm1,Adar,Cd200,Ripk3,H2-Q4,Cysltr2,Crkl,Stat1,Nlrc4,Mndal,Optn,Dnase1l3,Swap70,Hk3 |
| 2.914e-66 | -150.90 | NUYTTEN_EZH2_TARGETS_UP | MSigDB lists | NUYTTEN_EZH2_TARGETS_UP | 930 | 241 | 15632 | 1249 |
Slc16a3,Ifi209,Tcf4,Oas3,Batf2,Sat1,Ogfrl1,Mecp2,Glipr2,Aim2,Ifih1,Tab2,Kmo,Slc39a13,Myd88,Mvp,Gja1,Ccr1,Serpine1,Map2k1,Fzd5,Ddit4,Parp12,AA467197,Car13,Mmp13,Hmox1,Ripk2,Cdc42ep4,Fcho2,Gcnt2,Kitl,Plat,Pcdh7,Cxcl1,Il1b,Rnf114,Morc3,Spsb1,Klf3,Parp14,Bnip3,Ctsc,Pla2g4a,Parp9,Optn,Tpi1,Nek6,Fas,Rtp4,Zc3hav1,Spred1,Vezt,Trim14,Isg20,Srxn1,Ifi211,Xaf1,Stx6,Tdrd7,Oasl1,Hmgcs1,Ifi204,Dnajb4,Gbp2b,Ust,Fam162a,Sp140,Ehd1,Birc2,Slc2a1,Tank,Dse,Slc15a3,Egr2,Fut8,Tapbp,Mlkl,Stk40,Lztfl1,Irf2,St3gal6,Socs1,Trim12c,Traf1,Stat2,Ddx58,Cd83,Gbp2,Rgl1,Ccnj,Jarid2,Nampt,Plk2,Ppm1k,Ube2l6,Ldha,Oas1g,Herc6,Cxcl10,Clic4,Serpinb2,Thbs1,Vegfc,Agrn,Flrt3,Tspan3,Znfx1,Il4i1,Prkce,Edn1,Egr1,Atf3,Nlrp3,Arrdc4,Xrn1,Plagl1,Adar,Pnpt1,Phf11c,Tnks1bp1,Tap1,Lnpep,P4ha1,Birc3,Psmb8,Cd69,Ifi203,Hivep3,Oas1a,Stat1,Casp7,Endod1,Azi2,Adrb2,Phf11d,Cflar,Armc8,Klf6,Phf11b,P4ha2,Serp1,Ifi44,Tnc,Nfkbie,Errfi1,Gbp3,Usp18,Tnfaip3,Ncoa7,Gdf15,Myadm,Plekha4,Arl5b,Wdfy1,Inhba,Vasn,Tlr3,Xkr8,Arid5b,Usp42,Rcan1,Epsti1,Sod2,Sqstm1,Dhrs9,Eif2ak2,Dnaja1,Ets2,Tor1aip2,Ifnb1,Cept1,Nck1,Ddx60,Ifi214,Phf11a,Slfn5,Ifi207,Dcun1d3,Ahrr,Plod2,Mndal,Lap3,Gem,Psme2,Trim21,Csf1,Rhou,Max,Dram1,Clcn7,Jak2,Frmd6,Cdkn1a,Mob3c,Casp1,Parp8,Ifi213,Eno1,Ifi205,Psmb9,Rhoq,Dennd1b,C1ra,Pml,Mxd1,Dtx3l,Sphk1,Icam1,Rhoc,Junb,4930523C07Rik,Slc31a2,Ifi208,Nmi,Hk2,Wars,Tgfbi,Ptgs2,Tnfsf10,Glrx,Slc37a3,Dcbld2,Il15ra,Nfkbia,Jun,Il6,Samd9l,Prnp,Tmtc2,Rras2,Prdx1,Rnd3,Samhd1,Abtb2,Zc3h12c,Plscr1,Ube2e2,Tlr2,Irf1,Zcchc2 |
| 4.126e-66 | -150.55 | GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN | MSigDB lists | GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN | 148 | 94 | 15632 | 1249 |
St7,Map3k8,Cox18,Parp3,Pcgf5,Xkr8,Tlr3,Fam53c,Irak2,Golga3,Igsf9,Vasp,Sap30,Rab10,Psmb10,Csrnp1,Aim2,Ccdc88b,Ube2f,Cd14,Rnf34,Tpst1,Klf6,Tlk2,Oaf,Rab20,Rnf145,Tnip3,Max,Dusp16,H3f3b,Rap2c,Notch2,Lmo4,Rnf14,Nfkb1,Tdrd7,Zfp36,Nfkbib,Spen,Aldh1b1,Kat2b,Usp25,Zc3hav1,Foxp4,Klf7,Slamf7,Il15,Ptpn2,Gsdmd,Dusp4,Scarf1,Optn,Ptafr,Kcna3,Ptgs2,Kdm6b,Plaur,Rsbn1,Ccnj,Sell,Calcrl,Mthfr,Marcksl1,Irf2,Myo10,Casp1,Mlkl,Slc15a3,Nr3c1,Aida,Tmod3,Ppa1,Tmem219,Tmem67,Plekha2,Ogfr,Mier3,Hivep3,Plscr1,Dtwd1,Pttg1,Mapkapk2,Abr,Ppfibp1,Chmp4b,Cdc42ep2,Pnpt1,Hinfp,Pik3r5,Rab32,Kremen1,Bbx,Edn1 |
| 6.145e-66 | -150.15 | GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN | 191 | 106 | 15632 | 1249 |
Hspa1a,Dusp1,Ehd1,Setdb2,Egr2,Gpr84,Traf1,Malt1,Marcksl1,Ier2,Relb,Plk2,Junb,Maff,Nfkbid,Slc2a6,Phlda1,Btg2,Cxcl10,Pim1,Ptgs2,Zc3h12a,Dusp5,Dnaja2,Kdm6b,Rnf19b,Ptger4,5430427O19Rik,Slfn3,Jun,Tiparp,Fos,Ccl12,Nfkbia,Myc,Ccl2,Peli1,Etv3,Trim13,Egr1,Atf3,Nfkbiz,Cdc42ep2,Rnd3,Slc25a25,Zc3h12c,Il10,Birc3,Cd69,Ccrl2,Plscr1,Bcl9,Procr,Tlr2,Ier3,Irf1,Filip1l,Socs3,Rgs1,Cflar,Bcl6,Arid5a,Klf6,Tnf,Nfkbie,Errfi1,Tlk2,Usp18,Csrnp1,Tnfaip3,Cd14,Osm,Med21,Slfn4,Ppp1r15a,Gdf15,Pde4b,Cxcl2,Fam72a,Mmp13,Arl5b,Phlpp2,Ext1,Map3k8,4930453N24Rik,Rcan1,Osgin2,St3gal1,Cxcl1,Cited2,Sqstm1,Gadd45b,Dusp4,Ifrd1,Dusp2,Slamf7,Clec4e,Sdc4,Cenpj,Rel,Nfkbib,Zfp36,Rab20,Dnajb4,Odc1,Ccl4 |
| 8.659e-66 | -149.81 | GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_DN | MSigDB lists | GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_DN | 184 | 104 | 15632 | 1249 |
Olr1,Klf7,Pilra,Fas,Ift57,Mllt6,Mmp14,Ets2,Bcl2a1b,Ass1,Sod2,Syk,Aoah,Dusp16,Ccl4,Jak2,Fam102b,C3,Lmo4,Hdc,Irak3,Tnfaip3,Cd38,Ccdc88b,Hdac1,Nfkbie,Rab11fip1,Rhbdf2,Arhgef3,Tnf,Acp2,Il1b,Ptges,Nfkb2,Ralgds,Il2rg,Vasp,Cxcl2,Sh3bp4,Irf7,Cd274,Pde4b,Plek,Cdc42ep2,Zbp1,Rnd3,Nlrp3,Trim13,Ccl22,Nfkbiz,Psmd10,Slc7a11,Nfkbia,Rab32,Rnaset2b,Tnip1,Tnfaip2,Cflar,Mefv,Acsl1,Sema4a,Socs3,Filip1l,Cd69,Smpdl3b,Lcn2,Zc3h12c,Birc3,Abtb2,Relb,Hck,Nod1,Traf1,Bcl2a1d,Gsr,Cebpd,Lztfl1,Rhoq,Pnp2,Tank,Slc2a1,N4bp1,Ehd1,Src,Hcar2,Tfec,Gng12,Osbpl3,Acsl5,Bcl2a1a,Kif3c,Cxcl10,Ak4,Slamf8,Clec5a,Zc3h12a,Adora2a,Csf3,Pik3r6,Rnaset2a,Samsn1,Gch1,Snx10,Slc31a2 |
| 7.274e-65 | -147.68 | GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | 165 | 98 | 15632 | 1249 |
Kmo,Usp18,Upp1,Serp1,Txnrd1,Fgl2,Rbpms,Il2rg,St7,Pgk1,Ralgds,Lcp2,Pde4b,Inhba,Pde7b,Rab10,Cx3cl1,Fas,Klf7,Me1,F10,Sdc4,Cd80,Slamf7,Mrpl52,Ptpn2,Sqstm1,Rapgef5,Vcan,Ift57,Cpd,Mmp14,Odc1,Mthfd2,Rab20,Dtx2,C3,Dusp16,Jak2,Fscn1,Fam102b,Cav1,Pid1,Tnfrsf1b,Rap1gap2,Srxn1,Rtn2,Hif1a,Icam1,Ddx58,Slco3a1,Traf1,Itga4,Marcksl1,Relb,Cd83,Cd40,Src,N4bp1,Cst7,Stk40,Mlkl,Ly75,Kcna3,Il12b,Ptprj,Traf3ip2,Zc3h12a,Igf2bp2,Cmpk2,Lad1,Samsn1,Pik3r6,Slc7a2,Slc13a3,Tmem26,Antxr1,Tlr1,Nlrp3,Mapkapk2,Pfkfb3,Cdc42ep2,Nfkbia,Pik3r5,Flrt3,Nqo1,Mefv,Tlr2,Ebi3,Denr,Stat1,Prkar2b,Cflar,Lcn2,Rims3,Stat4,Cd69,Procr |
| 1.390e-64 | -147.04 | GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN | 184 | 103 | 15632 | 1249 |
Aim2,Parp10,Usp18,Kmo,Ifih1,Gbp3,Myd88,Ncoa7,Cd38,Ifit2,Phf11b,Ifi209,Oas3,Ifi44,Batf2,Dhx58,Rsad2,Atp10a,Epsti1,Sp110,Acp2,Ccr1,Lcp2,Irf7,Parp12,Ddx60,Tpx2,Ifi214,Rtp4,Il15,Phf11a,Ifi207,Plac8,Eif2ak2,Parp14,Rin2,Parp9,Oasl1,Ifi204,Mthfd2,Ifit3b,Jak2,Ldlr,Gbp2b,Vrk2,Mndal,Adap2,Lap3,Trim14,Ifi211,Psme2,Xaf1,Tdrd7,Stat2,Ddx58,Dtx3l,Isg15,Trim12c,Myo10,Axl,Ifi213,Psmb9,Ifi205,Rbbp8,Atp13a1,Herc6,Oas1g,Cxcl10,Il1rn,Tnfsf10,Fmnl2,Il15ra,Cmpk2,Ifit1bl2,Rgl1,Slc31a2,Gch1,Cnp,Ube2l6,Ifi208,Nmi,Oas2,Nlrp3,Pnpt1,Adar,Zbp1,Tap1,Phf11c,Cx3cr1,Ifit1bl1,Msr1,Il4i1,Samd9l,Ifi35,Stat1,Phf11d,Zcchc2,Psmb8,Ifit3,Plscr1,Timeless,Oas1a,Ifi203 |
| 1.939e-64 | -146.70 | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN | 192 | 105 | 15632 | 1249 |
Ripk2,Tlr3,Sp110,Irf7,Plekha4,Tap2,Trim26,Parp12,Psmb10,Ifih1,Usp18,Myd88,Phf11b,Ifit2,Oas3,Rhbdf2,Ifi209,H2-Q6,Arid5a,Ifi44,Dhx58,Rsad2,Oasl1,Max,Ifit3b,Ifi204,Jak2,Vrk2,Lap3,Mndal,Psme2,Ifi211,Csf1,Trim21,Trim14,Isg20,Tdrd7,Xaf1,Usp25,Ddx60,Rtp4,Ifi214,Phf11a,Il15,Zc3hav1,Ifi207,Rnf114,Eif2ak2,Gsdmd,Dnaja1,Optn,Oas1g,Rnf19b,Herc6,Cxcl10,Tnfsf10,Trafd1,Il15ra,Vegfc,Gch1,Ifit1bl2,Cnp,Nmi,Ifi208,Ube2l6,Oas2,Uba7,Wars,Pml,H2-Q7,Malt1,Irf2,Psme1,Socs1,Isg15,Ddx58,Stat2,Gbp2,Casp1,N4bp1,Ifi213,Ifi205,Psmb9,Rab9,Slc15a3,Stat1,Ppa1,Casp7,Ifi35,Irf1,Phf11d,Zcchc2,Rnf31,Psmb8,Ogfr,Ifit3,Plscr1,Ifi203,Oas1a,Adar,Tap1,Phf11c,Samhd1,Ifit1bl1,H2-Q4 |
| 7.034e-64 | -145.41 | GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP | MSigDB lists | GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP | 190 | 104 | 15632 | 1249 |
Slc25a12,Car13,Il12rb1,Parp12,Pde7b,Slfn4,Irf7,Epsti1,Keap1,Mitd1,Inpp1,Cox18,Tlr3,Rsad2,Dhx58,Ifi44,Gbp9,Oas3,Tpst1,Ifit2,Cutc,1600014C10Rik,Usp18,Ifih1,Prrg4,Tdrd7,Xaf1,Csf1,Trim21,Isg20,Lap3,Tor3a,Parp11,Ifit3b,Max,Oasl1,Parp9,Slfn8,Parp14,Tor1aip2,Katna1,Eif2ak2,Plac8,Rnf114,Dnase1l3,Slfn5,Il15,Sgcb,Rtp4,Nr1h3,Ddx60,Hap1,Oas2,Rilpl1,Nmi,Cd86,Nampt,Ifit1bl2,Trafd1,Cmpk2,Slfn3,Tnfsf10,Slfn9,Cxcl10,Herc6,Larp1,Oas1g,Setdb2,Slc15a3,Gbp4,Gypc,Notch1,Daxx,Ifit1,Gbp2,Hck,Stat2,Trim12c,St3gal6,Isg15,Dtx3l,Pml,Ccrl2,Oas1a,Cd69,Ifit3,Ubr4,Gbp7,Zcchc2,Fam111a,Ifi35,Ppa1,Stat1,Samd9l,Irgm2,Ifit1bl1,Nlrc5,Agrn,Chmp4b,Tnks1bp1,Samhd1,Pfkfb3,Zbp1,Nmral1 |
| 9.530e-64 | -145.11 | response to external stimulus | biological process | GO:0009605 | 2171 | 361 | 20694 | 1406 |
Ifna1,Acp5,Trim34a,Il1b,Isg15,Ifnar1,Ifi205,Tlr3,Cdk5r1,Prkce,Tnfrsf14,Nfkb1,Oas1g,Nmral1,Nrp2,Lhx2,Cpeb4,Bmp2,G3bp2,Saa3,Cnn2,Lox,Ednrb,Cd14,Ifitm1,Bnip3,Il12b,Agrn,Mefv,Ccdc88b,Cd55,Stxbp3,Tnip3,Gpr35,Ifna6,Nck1,AA467197,Abcc1,Cdkn1a,Trim56,H2-Aa,Mt2,P2ry12,Tnfrsf1b,Itga9,Plac8,Ifi211,Clec4n,Nlrp3,Zc3hav1,Lrp11,Jak2,Tlr6,Zbp1,Ddx58,Tnfaip3,Irf7,Peli1,Bcl2l11,Treml4,Ifit3b,Fpr2,Stat2,Oas1a,Tmem229b,Flt1,Arg2,Slc25a25,Raet1e,Pdgfrb,Fzd5,Ccl8,Ch25h,Nr1h3,Csf1,Ccl2,Oas3,Batf,Ppp1r14b,Slamf8,Nfkbia,Adrb2,Psmb9,Evl,Ifit3,Apobec3,Kif5c,Slfn9,Ifna2,Herc6,Eif2ak2,Slc2a1,Sirt1,Mmp9,Ccl22,Cd274,Lgals9,Acod1,Trim30a,Cxcl11,Klf7,Cav1,Plscr1,Ldha,Pik3cd,Spn,Cd86,Adora2b,H2-Eb1,Cyfip1,Slpi,Ptgs2,Ifit2,Oasl2,Nt5c3,Cd180,Mtdh,Gbp8,Nlgn2,Cd40,Slc16a1,Angpt1,Il27,Prdx1,Ly6a,Ccl12,Atf3,Stxbp1,Rnf135,Tnf,Jun,Rsad2,Zc3h12a,Il18,Slfn2,Gfi1,Mx1,Marco,Nfkbib,Usp53,Sbds,Clec5a,Casp4,Nfkbil1,Trim26,Ldlr,Casp1,Slfn4,Tifa,Ripk2,Irf4,Dtx3l,Itga4,Ccr3,Ptgir,C1ra,Ddx60,Resf1,Sema4c,Fas,Irf1,Phlpp1,Irf2,Cx3cr1,Il10,H60b,Cmklr1,Gbp7,Palld,Mapkapk2,Itgav,Gja1,Rtp4,Nr4a3,Trem1,Thbs1,Slfn8,Cacnb3,Samhd1,Sema4a,Il6,Ciita,Vasp,Cflar,Gdf15,Fabp7,Il1rn,Cgas,Ext1,Cxcl14,Vcam1,Tagap,Notch2,Irgm1,Myd88,Met,Arid5a,Gch1,Fcgr2b,Plaat3,Egr2,Gbp9,Nlrc5,Cx3cl1,Optn,Mndal,Stat1,Flrt3,Nlrc4,Crkl,Adar,Trib1,Il12rb1,Cxcl3,Tarm1,H2-Ab1,Egr3,Hck,Sema3c,Smpdl3b,Gbp3,Lcn2,Cxcl10,Ptafr,Pdgfb,Klrk1,Ikbke,Serpina3f,Batf2,Piezo1,Lpar1,Fcgr4,Tent5a,Myc,Htr2a,Oas1b,Ccl9,Rnf19b,Csf3r,Ntng2,Ccrl2,Tgtp1,Ifih1,Dock4,Fcgr1,Slc9a1,Gbp2,Pf4,Tlr9,Ddit4,Parp14,Iigp1,Mecp2,Vegfc,Ccl7,Trim12a,Cxcl1,Ier3,Dhx58,Hp,Trim13,Irf8,Axl,Slc39a4,Ptch1,Ifit1bl2,Usp18,Rab32,C1rl,Sell,Lyn,Il4ra,Adgrl2,Isg20,Higd1a,Ifit1,Gbp2b,Ifit1bl1,Cd80,Abr,Fos,Gsdmd,Malt1,Junb,Fpr1,Pde4b,Oas2,Tlr1,C3,Fgr,Ankrd17,Igf1r,Larp1,Trim14,Ccl5,Cxcl2,Serpinb9,Ifnb1,Cdkn2d,Nod1,Rab20,Noct,Prdm1,Ago3,Zyx,Pml,Ccr1,Ccl4,Syk,Oasl1,Ifi204,Ccl3,Sod2,Slamf7,Irak2,Ifi44,Rgs1,Flnb,Pim1,Clec4e,Tlr2,Clec4d,Mx2,Asns,Cdc42ep2,Ptprj,Nmi,Stx11,Tnfsf8,Cmpk2,Xcr1,Scn1b,Cxcl9,Gbp4,Wdr59,Nos2,Tab2,Parp9,Irgm2,Sesn3,Ifna4,Zfp36,Irak3,Clic5,Trim21,Stap1,Sp110,H2-Q7,Tap2,Serpine1,Nod2,Flrt2,Cdc42ep4,Nr4a1,Tnfsf4,S100a8,Mcoln2,Ptger4,Aim2,Adora2a,Shfl |
| 1.049e-63 | -145.02 | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN | 183 | 102 | 15632 | 1249 |
Nat2,Lrch1,Rnf114,Bcl2a1b,Spred1,Slfn5,Tle3,Nck1,Dcp2,Aldh1b1,P2ry14,Kctd12,Stx6,Tor3a,Mov10,Adap2,Whamm,Znrf1,Chd9,Cdkn1a,Cpeb4,Mtdh,Cacnb3,D1Ertd622e,Stat3,1110038F14Rik,Arhgap26,Dock10,Plod3,Traf2,Oas3,Tcf4,Rnf34,Traf5,Ncoa7,Rab3ip,Apaf1,Mvp,Plagl2,Rnf135,Trim26,Mmp13,Slc25a12,Cxcl2,Fzd1,Brwd3,Cd274,Lrp11,Xkr8,Fam53c,Usp42,Gpr85,Map3k8,Triobp,Flt1,Hivep2,Flrt3,Rras2,Adar,Vcpip1,Pgs1,Abr,Atf3,Dtwd1,Akt3,Flnb,Ube2e2,Mier3,Il10,Plekha2,Gbp7,Tnfaip2,Tmod3,Filip1l,Dyrk2,Slc25a22,Acsl1,Lztfl1,Zfp800,Bcl2a1d,Src,Spryd7,Rbbp8,Tank,Birc2,Cd83,Mapkbp1,Psme1,Caml,Wars,Arid4a,Junb,Rgl1,Daam1,Asah2,Plcl2,Bcl2a1a,Rsbn1,Il1rn,Clic4,Tfec,Tapbpl |
| 1.244e-63 | -144.84 | GSE42724_NAIVE_VS_B1_BCELL_UP | MSigDB lists | GSE42724_NAIVE_VS_B1_BCELL_UP | 187 | 103 | 15632 | 1249 |
Inpp5b,Phlda1,Nfkbid,Wars,Dgka,Hk2,Arid4a,Junb,Slc4a7,Rgl1,Slc7a8,Ifit1bl2,Ppm1k,Zhx2,Larp1,Grina,Nr3c1,Setdb2,Rab9,Pnp2,Mdm2,Parp8,Plekhf2,Ifnar1,Casp1,Hspa1a,Crlf3,Smg7,Pml,Stat2,Slc39a14,Ankib1,Ptch1,Sh3bgrl2,Kpna3,Etnk1,Ppa1,Irf1,Il18bp,Triobp,Ifit1bl1,Fcgr1,Mapkapk2,Phip,Trim13,Nrp2,Bst1,Sh3bp4,Rapgef2,Vasp,Igsf9,Pde4b,Gja1,Tap2,Golga3,Irak2,Ppp2r2a,Naa25,Frmd4a,Stat3,D1Ertd622e,Rab11fip1,Nfkbie,Arhgap26,Ythdf1,Armcx6,Tnf,Tcf4,Rnf34,Cutc,Apaf1,Tnfaip3,Plk3,Csrnp1,Pigv,Psmb10,Zeb1,Trim14,Ppp4r2,Pou2f2,Rhou,Ppp1r15b,Rnf14,Hk1,Rel,Hdc,Plod2,Cenpj,Whamm,Clcn7,Lhx2,Vrk2,Dram1,Parp11,Asb13,Vcan,Cept1,Parp9,Cited2,Fbrsl1,Bcor,Ubash3b,Znrf3 |
| 1.618e-63 | -144.58 | defense response to other organism | biological process | GO:0098542 | 760 | 196 | 20694 | 1406 |
Rsad2,Tnf,Oasl1,Ccl3,Rnf135,Syk,Ccl4,Stxbp1,Zyx,Pml,Ccl12,Prdx1,Prdm1,Il27,Rab20,Ifnb1,Nod1,Serpinb9,Ccl5,Trim14,Gbp8,Ankrd17,Fgr,Cd40,Cd180,C3,Nt5c3,Tlr1,Oas2,Malt1,Gsdmd,Oasl2,Ifit2,Ifit1bl1,Slpi,H2-Eb1,Ifit1,Gbp2b,Isg20,Cd86,Pik3cd,Spn,Plscr1,Lyn,Il4ra,Trim30a,C1rl,Acod1,Ifit1bl2,Hp,Trim13,Irf8,Axl,Dhx58,Ccl22,Shfl,Aim2,Mcoln2,Gbp7,Cx3cr1,S100a8,H60b,Il10,Irf2,Tnfsf4,Cdc42ep4,Irf1,Serpine1,Nod2,H2-Q7,Sp110,Trim21,C1ra,Ddx60,Dtx3l,Irf4,Ripk2,Parp9,Tifa,Ifna4,Irgm2,Nos2,Gbp4,Cxcl9,Casp1,Nmi,Tnfsf8,Stx11,Casp4,Trim26,Clec5a,Cdc42ep2,Mx2,Clec4e,Clec4d,Tlr2,Flnb,Marco,Mx1,Slamf7,Il18,Cx3cl1,Nlrc5,H2-Aa,Gbp9,Trim56,Gch1,Arid5a,Ifna6,Irgm1,Myd88,Notch2,Tagap,Stxbp3,Ccdc88b,Cd55,Cgas,Il12b,Mefv,Bnip3,Ifitm1,Cd14,Ciita,Il6,G3bp2,Samhd1,Slfn8,Trem1,Tnfrsf14,Oas1g,Tlr3,Rtp4,Ifnar1,Isg15,Trim34a,Ifna1,Acp5,Trim12a,Ccl7,Eif2ak2,Herc6,Slfn9,Apobec3,Iigp1,Ifna2,Parp14,Ddit4,Ifit3,Slamf8,Gbp2,Fcgr1,Evl,Tlr9,Pf4,Ppp1r14b,Batf,Oas3,Ccl2,Csf1,Ifih1,Tgtp1,Rnf19b,Ccl9,Oas1b,Ccl8,Batf2,Ikbke,Klrk1,Raet1e,Cxcl10,Oas1a,Arg2,Fpr2,Lcn2,Stat2,Gbp3,Ifit3b,Treml4,Smpdl3b,H2-Ab1,Hck,Irf7,Tarm1,Il12rb1,Ddx58,Adar,Zbp1,Jak2,Tlr6,Stat1,Nlrc4,Zc3hav1,Nlrp3,Clec4n,Plac8,Optn |
| 2.056e-63 | -144.34 | GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_DN | 155 | 94 | 15632 | 1249 |
Cnp,Oas2,Stoml1,Nmi,Nsmaf,Cmpk2,Trafd1,Slc37a3,Tnfsf10,Elmod2,Gpsm2,Casp1,Plekhf2,Lrp4,Parp8,Lipe,Axl,Tapbp,Dbnl,Setdb2,Slc15a3,Nr3c1,Mthfr,Pml,Irf2,Gbp2,Daxx,Ifit3,Casp2,Cd69,Timeless,Phf11d,Stat1,Endod1,Ifi35,Ap3m2,Tmem219,Znfx1,Flt1,Samd9l,Edn1,Pttg1,Prnp,Phf11c,Rbm43,Rnd3,Flrt2,Parp12,Rapgef2,Nr4a3,Pcgf5,Rtn1,Atp10a,Tlr3,Fam53c,Sp110,Gtpbp2,Tpst1,Phf11b,Ccng2,Mafk,Tnfsf8,Stat3,Gbp3,Rnf135,Kmo,Usp18,Csrnp1,Lipg,Myd88,Rnf34,Casp8,Hdc,Plod2,Cenpj,Adap2,Mov10,Xaf1,Zeb1,Isg20,Trim21,Ifit3b,Asb13,Gbp2b,Spsb1,Gadd45g,Phlpp1,Dusp2,Tor1aip2,Aldh1b1,Stxbp1,Atp11b,Phf11a,Fbrsl1 |
| 2.180e-63 | -144.28 | GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN | 184 | 102 | 15632 | 1249 |
Cdyl2,Rsad2,Rhbdf2,Ifit2,Zswim4,Hvcn1,Ncoa7,Plagl2,Ube2f,Fabp3,Prdm1,Plk3,Rapgef2,Vasn,Rab10,Ext1,Ppp1r15a,Lcp2,Rcl1,Ikbke,Irak2,Gpr85,Ifrd1,Mmp14,Ptpn2,Gadd45b,Sqstm1,Bcl2a1b,Syk,Foxp4,Sdc4,Cd80,Fpr2,Sdc1,Nr1h3,Cx3cl1,Fas,Isg20,Pstpip2,Srxn1,Psme2,Alas1,Atxn7l1,Lmo4,Tor3a,Tnfrsf1b,Ednrb,Abcc1,Jak2,Znrf1,Ccl4,Rab20,Ifit3b,C3,Mdm2,Bcl2a1d,Slc2a1,Spryd7,Ifit1,Hck,Fgr,Traf1,Tmem26,Phlda1,Slc2a6,Scn1b,Lad1,Slc31a2,Jarid2,Plaur,Il1rn,Bcl2a1a,Gca,Serpinb2,Slamf8,Clec5a,Il12b,Ptprj,Dnaja2,Ncoa5,Peli1,Rhof,Nlrc5,Agrn,Slc7a11,Flrt3,Ccl12,Ciita,Etv3,Lrp8,Smpdl3b,Met,Procr,Ifit3,Casp4,Rabgef1,Cflar,Fam20c,Tnfaip2,Irf1,Gpd2,Ebi3 |
| 4.528e-63 | -143.55 | FOSTER_TOLERANT_MACROPHAGE_UP | MSigDB lists | FOSTER_TOLERANT_MACROPHAGE_UP | 139 | 89 | 15632 | 1249 |
Cdc42ep2,Slc7a11,Adhfe1,Rab32,Psmd10,Msr1,Igsf6,Ppfia3,Il18bp,Ell2,Stat1,Cd200,Acsl1,Rgs1,Lcn2,Zc3h12c,Itgal,Marco,Met,Rasgrp1,Jag1,Agtrap,Sell,Clmp,Cst7,Tank,Serpinb9,Fpr1,Lox,Tgfbi,Thbs1,Il1rn,Glrx,Dcbld2,Rgl1,Slc7a8,Slc13a3,Slc31a2,Slc7a2,Adora2a,Clec4e,Tspo,Fbrsl1,F10,Ass1,Syk,Aoah,Gpr18,Spic,Ift57,Ifrd1,Phlpp1,Mtdh,Rab20,Mthfd2,Orai2,Lrrc8c,Gsta3,Tnfrsf1b,Lmo4,Gem,Atxn7l1,Isg20,Fabp7,Xaf1,Slamf9,Nupr1,Mcoln2,Fabp3,Irak3,Cd38,Txnrd1,Slc16a3,Slc25a37,Oas3,Ifi44,Cp,Cycs,Prdx5,Fgl2,Treml2,Rbpms,Slc31a1,Hp,Ptges,4933430I17Rik,Irf7,Rab10,Bst1 |
| 5.193e-63 | -143.42 | GSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_UP | 189 | 103 | 15632 | 1249 |
Oas1g,Herc6,Cxcl10,Serpinb9,Fpr1,Slamf8,Tnfsf10,Clic4,Slfn9,Cmpk2,Gch1,Snx10,Ifit1bl2,Nmi,Ube2l6,Oas2,Uba7,Wars,Mthfr,Pml,Psme1,Trim12c,Isg15,Dtx3l,Ddx58,Rab19,Stat2,Nod1,Hck,Gbp2,Daxx,Ifit1,Apobec3,Cd40,Psmb9,Setdb2,Pnp2,Gbp4,Dck,Stat1,Etnk1,Ifi35,Aida,Irf1,Psmb8,Dach1,Gbp7,Ifit3,Il10,Cd69,Oas1a,Sass6,Zbp1,Adar,Fcgr1,Tap1,Samhd1,Ifit1bl1,Znfx1,Ccl2,Irgm2,Samd9l,Il18bp,Cd200r4,Tlr3,Inpp1,Sp110,Map2k1,Irf7,Cd274,Parp12,Ch25h,Gbp3,Psmb10,Ifih1,Usp18,Upp1,Gnb4,Ifit2,Oas3,Batf2,Ifi44,Gbp9,Dhx58,Rsad2,Fgl2,Oasl1,Ifit3b,Ddx4,Parp11,Arf4,Trim21,Isg20,Xaf1,Rtp4,Fpr2,Il15,Slfn5,Rnf114,Eif2ak2,Slfn8,Parp14,Parp9 |
| 8.334e-63 | -142.94 | regulation of response to stress | biological process | GO:0080134 | 1318 | 266 | 20694 | 1406 |
Mlkl,Mdm2,Slc7a2,Ifna1,Acp5,Mapkapk2,Pmaip1,Il1b,Hmga2,Ifi205,Nfkbiz,Tlr3,Gja1,Ikbkg,Nfkb1,Psmd10,Prkce,Nr4a3,Plk2,Thbs1,Cd34,Fbxo4,Plek,Bmp2,Ctsc,Samhd1,Il6,Dusp1,Hif1a,Mid1,Bcl6,Ifi214,Ppp1r15a,Ednrb,Cd14,Cst7,Txn1,Traf3ip2,Cgas,Il1rn,Il12b,Mefv,Gadd45b,Spred3,Kmt5a,Fut8,Tmem67,Calcrl,Tnip3,Nck1,Irgm1,Met,Myd88,Cdkn1a,Siglece,Nampt,Gch1,Pla2g4a,Fcgr2b,Nlrc5,Ubash3b,Cx3cl1,Mdfic,Ifi211,Optn,Dnase1l3,Tnfrsf1b,Hk3,Akt3,Zc3hav1,Mndal,Nlrp3,Zbp1,Sphk1,Tlr6,Jak2,Stat1,Errfi1,Nlrc4,Tnfaip3,Irf7,Tarm1,Rictor,Il12rb1,Cd200,Adar,Ddx58,Dek,Treml4,Smpdl3b,Peli1,Fpr2,Trim12c,Map2k1,Pdgfb,Klrk1,Raet1e,Arg2,Ikbke,Myc,Pde5a,Ptpn2,Fzd5,Ppp4r2,Clec2d,Nr1h3,Ifih1,A530064D06Rik,Nupr1,Il15,Slamf8,Fcgr1,Nfkbia,Adrb2,Tlr9,Ccl2,Parp14,Ezr,D1Ertd622e,Trafd1,Glrx,Eef1e1,Apobec3,Socs3,Stat5a,Cxcl1,Socs1,Pdpn,Hopx,Eif2ak2,Pnpt1,Ier3,Sirt1,Grina,Lgals9,Dhx58,Pik3r6,Tap1,Usp18,Acod1,Cav1,Lyn,Kremen1,Osm,Ncoa7,Tnip1,Slc7a11,Ifi209,Trim30a,Spire1,Clcf1,Hsph1,Timeless,Spn,Plscr1,Adora2b,Cd86,Atm,Abr,Ptgs2,Cd200r4,Aida,Treml2,Parp3,Cd74,C3,Tlr1,Ankrd17,Fgr,Rbl1,Igf1r,Fignl2,Nox1,Nod1,Cdkn2d,Rabgef1,Serpinb9,Ccl5,Bfar,Il27,Prdx1,Ccr1,Pml,Eya4,Rasgrp1,Rnf135,Syk,Sod2,Rsad2,Fzd1,Tnf,Mapkbp1,Ifi204,Il1a,Ccl3,Irak2,Cd300lf,Zc3h12a,Fgl2,Gfi1,Scarf1,Uaca,Clec4e,Tlr2,B430306N03Rik,Map4k4,Nfkbil1,Ifi203,Pvr,Casp1,Nmi,Ldlr,Ptprj,Aoah,Il18rap,Usp25,Spred1,Traf2,Htra1,Parp9,Ripk2,Ifi208,Mul1,Tifa,Sesn3,Irgm2,Nos2,Gbp4,Wdfy1,Dtx3l,Irak3,Gadd45g,Ctla2a,Irf4,Zfp36,Ddx60,Enpp4,Nectin2,Dnaja1,Edn1,Stap1,Sema4c,Elmod2,Serpine1,Radx,Nod2,Lrp8,Tap2,Fas,Phlpp1,Irf1,Plau,S100a8,Cx3cr1,Il10,H60b,Ppp1r15b,Map2k4,Tnfsf4,Plpp3,Abcb1a,Ptger4,Atp2b4,Bst1,Aim2,Adora2a |
| 1.850e-62 | -142.15 | regulation of defense response | biological process | GO:0031347 | 624 | 175 | 20694 | 1406 |
Nupr1,Il15,A530064D06Rik,Ifih1,Clec2d,Nr1h3,Ptpn2,Pde5a,Socs1,Cxcl1,Stat5a,Apobec3,Socs3,Trafd1,Parp14,D1Ertd622e,Slamf8,Fcgr1,Tlr9,Nfkbia,Adrb2,Cd200,Ddx58,Adar,Tnfaip3,Irf7,Rictor,Tarm1,Il12rb1,Jak2,Tlr6,Stat1,Nlrc4,Sphk1,Zbp1,Mndal,Nlrp3,Zc3hav1,Tnfrsf1b,Ifi211,Optn,Dnase1l3,Ikbke,Arg2,Klrk1,Raet1e,Trim12c,Fpr2,Peli1,Treml4,Smpdl3b,Tnip3,Calcrl,Cgas,Traf3ip2,Il12b,Mefv,Cst7,Ednrb,Cd14,Bcl6,Ifi214,Cx3cl1,Nlrc5,Pla2g4a,Fcgr2b,Siglece,Irgm1,Myd88,Prkce,Nfkb1,Gja1,Ifi205,Nfkbiz,Tlr3,Il1b,Mapkapk2,Ifna1,Acp5,Slc7a2,Il6,Samhd1,Ctsc,Lrp8,Tap2,Serpine1,Nod2,Stap1,Elmod2,Nectin2,Ddx60,Irf4,Ctla2a,Zfp36,Irak3,Dtx3l,Aim2,Adora2a,Bst1,Ptger4,Tnfsf4,Cx3cr1,S100a8,H60b,Il10,Irf1,Clec4e,Tlr2,B430306N03Rik,Uaca,Gfi1,Zc3h12a,Fgl2,Cd300lf,Irak2,Nos2,Gbp4,Wdfy1,Mul1,Ripk2,Parp9,Ifi208,Tifa,Irgm2,Htra1,Ldlr,Nmi,Aoah,Il18rap,Ifi203,Pvr,Casp1,Nfkbil1,Serpinb9,Rabgef1,Ccl5,Nod1,Ankrd17,Fgr,Tlr1,Cd74,C3,Treml2,Cd200r4,Tnf,Mapkbp1,Ifi204,Ccl3,Rsad2,Rnf135,Rasgrp1,Ccr1,Pml,Il27,Ifi209,Trim30a,Clcf1,Cav1,Lyn,Osm,Tnip1,Acod1,Usp18,Dhx58,Pik3r6,Tap1,Lgals9,Ier3,Ptgs2,Abr,Atm,Cd86,Adora2b,Plscr1,Spn |
| 3.642e-62 | -141.47 | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN | 162 | 95 | 15632 | 1249 |
Etv3,Atf3,Nfkbiz,Il6,Peli1,Edn1,Kcnj2,Znfx1,Ifit1bl1,Nfkbia,Tnip1,Rgs1,Tnfaip2,Cflar,Acsl1,Irf1,Socs3,Rasgrp1,Stat4,Ccrl2,Zc3h12c,Irf8,Ifit3,Birc3,Relb,Isg15,Traf1,Icam1,Il1a,Pml,Marcksl1,Ehd1,Dusp1,Cmpk2,Plaur,Il15ra,Cxcl10,Ptgs2,Kcna3,Dusp5,Zc3h12a,Herc6,Ptger4,Stx11,Btg2,Ifit1bl2,Nampt,Junb,Zc3hav1,Klf7,Slamf7,Pim3,Il15,Rtp4,Ifnb1,Vcan,Dusp2,Trip10,Cdkn1a,Ldlr,Ifit3b,Dnajb4,Oasl1,Dram1,Il18rap,Usp12,Isg20,Gem,Rel,Nfkb1,Dcun1d3,Tnfaip3,Rab3ip,Batf,Ifih1,Csrnp1,Plk3,Rsad2,Ifi44,Itgb8,Batf2,Rab21,Ifit2,Cxcl1,Map3k8,Nr4a3,Ripk2,Cxcl2,AA467197,Rapgef2,Arl5b,Gpr132,Irf7,Ppp1r15a,Cd274 |
| 1.414e-61 | -140.11 | GSE2706_UNSTIM_VS_2H_LPS_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_LPS_DC_DN | 171 | 97 | 15632 | 1249 |
Nfkb1,Dcun1d3,Rel,Gem,Isg20,Nfkbib,Usp12,Il18rap,Ptgir,Oasl1,Tnip3,Ifit3b,Ldlr,Cdkn1a,Gadd45b,Sod2,Parp14,Dusp2,Ifnb1,Pim3,Cd80,Zc3hav1,Cd274,Irf7,Trim26,Gpr132,Arl5b,Inhba,Rapgef2,AA467197,Cxcl2,Ripk2,Map3k8,Nr4a3,Cxcl1,Irak2,Rab21,Ifi44,Itgb8,Csrnp1,Ifih1,Batf,Plagl2,Tnfaip3,Birc3,Il10,Ifit3,Irf8,P2ry2,Jag1,Ccrl2,Rasgrp1,Socs3,Ell2,Irf1,Acsl1,Cflar,Tnip1,Tnfaip2,Rgs1,Ifit1bl1,Fam43a,Nfkbia,Pik3r5,Znfx1,Edn1,Kcnj2,Peli1,Il6,Atf3,Nfkbiz,Etv3,Tap1,Ifit1bl2,Nampt,Sipa1l1,Btg2,Slc2a6,Stx11,Herc6,Kdm6b,Ptger4,Zc3h12a,Dusp5,Slc43a3,Cxcl10,Il12b,Plaur,Ehd1,Otud1,Marcksl1,Pml,Icam1,Il1a,Isg15,Traf1,Relb |
| 5.059e-61 | -138.84 | GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_UP | 169 | 96 | 15632 | 1249 |
Phf11b,Ifit2,Oas3,Ifi209,Batf2,Ifi44,Sat1,Rsad2,Dhx58,Csrnp1,Ifih1,Usp18,Myd88,Gnb4,Irf7,Serpine1,Cd274,Tap2,Trim26,Parp12,Sp110,Eif2ak2,Dnaja1,Parp14,Parp9,Optn,Ddx60,Cx3cl1,Ifi214,Phf11a,Zc3hav1,Ifi207,Lap3,Mndal,Mov10,Psme2,Ifi211,Trim14,Trim21,Tdrd7,Xaf1,Trim56,Oasl1,Ifit3b,Ifi204,Gbp2b,Casp1,Ifi213,Ifi205,Birc2,Psmb9,Pml,Psme1,Irf2,Trim12c,Agtrap,Dtx3l,Isg15,Ddx58,Stat2,Ifit1bl2,Ppm1k,Nmi,Ifi208,Ube2l6,Oas2,Oas1g,Herc6,Cxcl10,Tapbpl,Cmpk2,Ifit1bl1,Nlrc5,Znfx1,Samd9l,Rbm43,Adar,Pnpt1,Pfkfb3,Phf11c,Tap1,Samhd1,Atp2b4,Lnpep,Psmb8,Ankib1,Ogfr,Ifit3,Plscr1,Ifi203,Oas1a,Stat1,Ifi35,Casp7,Fam111a,Phf11d |
| 1.076e-60 | -138.08 | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN | 170 | 96 | 15632 | 1249 |
Clcf1,Cflar,Tnfaip2,Tmem123,Tagap,Ebi3,Socs3,Ier3,Acsl1,Pdss1,Birc3,Il10,Pfkfb3,Nfkbiz,Nlrp3,Kcnj2,Peli1,Il6,Nfkbia,Rhof,Bcl2a1a,Clic4,Il15ra,Rnf19b,Ptprj,Zc3h12a,Kcna3,Ptgs2,Il12b,Ptafr,Slc2a6,Csf3,Stx11,Nampt,Snx10,Gch1,Samsn1,Ppm1k,Cd83,Hck,Rhoh,Icam1,Il1a,Traf1,Psma6,Bcl2a1d,Ehd1,Plekhf2,Tank,Cd40,Birc2,Fscn1,Rap2c,Ldlr,Ccl4,Dram1,Oasl1,Tnip3,Rcsd1,Tifa,Rhou,Dcun1d3,Ppp1r15b,Nfkb1,Sdc4,Pilra,Pim3,Clec4e,Zc3hav1,Dusp2,Rin2,Gramd1a,Plac8,Bcl2a1b,Sod2,Dnaja1,Cxcl1,Irak2,Il1b,Ripk2,Map3k8,Gpr132,Slc25a12,Rapgef2,Cd274,Sav1,Tnfaip3,Plk3,Mcoln2,Tab2,Rnd1,Ifih1,Rab21,Itgb8,Stat5a,Tnf |
| 1.076e-60 | -138.08 | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN | 170 | 96 | 15632 | 1249 |
Hivep2,Nfkbia,Rhof,Igsf6,Peli1,Il6,Kcnj2,Nfkbiz,Nlrp3,Pfkfb3,Birc3,Il10,Pdss1,Socs3,Ebi3,Ier3,Acsl1,Tnfaip2,Tnip1,Cflar,Clcf1,Tagap,Plekhf2,Ehd1,Tank,Birc2,Gpr84,Psma6,Bcl2a1d,Rhoh,Traf1,Il1a,Icam1,Cd83,Hck,Gch1,Samsn1,Scn1b,Slc2a6,Stx11,Csf3,Zc3h12a,Rnf19b,Ptprj,Il12b,Kcna3,Ptgs2,Clic4,Bcl2a1a,Il15ra,Bcl2a1b,Sod2,Gramd1a,Plac8,Dnaja1,Dusp2,Rin2,Clec4e,Pilra,Sdc4,Pim3,Zc3hav1,Dcun1d3,Ppp1r15b,Nfkb1,Tifa,Rhou,Pim2,Oasl1,Dram1,Rcsd1,Tnip3,Ccl4,Rap2c,Ldlr,Stat5a,Tnf,Itgb8,Mcoln2,Plk3,Rnd1,Tab2,Sav1,Tnfaip3,Pde4b,Cd274,Arl5b,Gpr132,Cxcl2,Rapgef2,Ripk2,Map3k8,Il18,Irak2,Cxcl1,Il1b |
| 1.814e-60 | -137.56 | GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN | MSigDB lists | GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN | 182 | 99 | 15632 | 1249 |
Cxcl10,Dnaja2,Smox,Hap1,G3bp2,Nfkbid,Slc2a6,Ascc3,Sesn3,Slc7a8,Mcmbp,Hck,Cd164,Smg7,Bfar,Spata13,Pml,Hhex,Psme1,Ube2e1,Zfp800,Ccdc86,Dbnl,Pnp2,Dennd1b,Minpp1,Otud1,Apobec3,Casp1,Axl,Parp8,Azi2,Ms4a6d,Filip1l,Endod1,Hat1,Pdss1,Plekha2,Ogfr,Slc28a2,Vcpip1,Chmp4b,Adar,Fbxo4,Hinfp,Prnp,Pttg1,Etv3,Nfkbiz,Peli1,Ccl2,Spry2,Fos,Ccl12,Dusp28,Snn,Gcnt2,Mitd1,Slc29a3,Il18,Phyh,Usp42,Xkr8,Parp12,Fam72a,Osm,Gnb4,Myd88,Rnf34,Pigv,Fabp3,Lrch3,Ccng2,Glipr2,D1Ertd622e,Tcf4,Oas3,Arhgef3,Plod3,Cdkn1a,Lyn,Parp11,Tdrd7,Slamf9,Isg20,Spen,Casp8,Plekhg1,Rbl1,Tspo,P2ry14,Slc30a1,Kat2b,Usp25,Phlpp1,Rin2,Tor1aip2,Ass1,Morc3 |
| 2.354e-60 | -137.30 | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP | MSigDB lists | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP | 206 | 105 | 15632 | 1249 |
Nck1,Sdc4,Il15,Olr1,Slfn5,Sod2,Sqstm1,Bcl2a1b,Spsb1,Oasl1,Dram1,Sema4c,Ifit3b,Lyn,Gbp2b,Cdkn1a,Dusp16,Nfkb1,Isg20,Ifih1,Usp18,Tnfaip3,Ncoa7,Rab3ip,Klf6,Rab11fip1,Itgb8,Oaf,B3gnt5,Ccng2,Nfkbie,Ripk2,Cdc42ep4,Rcan1,Nfkb2,Irak2,Cxcl1,Il1b,Ccl5,Ddit4,Gpr132,Cxcl2,AA467197,Mmp13,Inhba,Nfkbiz,Atf3,Gclc,Plau,Tap1,Nfkbia,Ifit1bl1,Rhof,Dock4,Znfx1,Il4i1,Peli1,Stard5,Edn1,Tmem171,Taf4b,Socs3,Tlr2,Irf1,Tnfaip2,Tnip1,Abtb2,Birc3,Zc3h12c,Ifit3,Lif,Pml,Mxd1,Marcksl1,Traf1,Slco3a1,Il1a,Ddx58,Icam1,Bmp2,Cd83,Relb,N4bp1,Ehd1,Tank,Birc2,Dse,Bcl2a1d,Zc3h12a,Rnf19b,Cxcl10,Serpinb9,Ptafr,Tnfsf10,Bcl2a1a,Il1rn,Cmpk2,Plaur,Lacc1,Gch1,Ifit1bl2,Slc7a2,Slc2a6,Btg2,Maff |
| 3.168e-59 | -134.70 | GSE42021_TREG_VS_TCONV_PLN_UP | MSigDB lists | GSE42021_TREG_VS_TCONV_PLN_UP | 194 | 101 | 15632 | 1249 |
H2-Q4,Ifit1bl1,Ccl12,Dock4,Adar,Phf11c,Tap1,Samhd1,Atf3,Plscr1,Oas1a,Dcp1a,Ifi203,Psmb8,Ifit3,Irf8,Ogfr,Ifi35,Casp7,Stat1,Irf1,Phf11d,Fam111a,Cebpd,C1ra,Tapbp,Ifi213,Psmb9,Ifi205,Nod1,Gbp2,H2-Q7,Pml,Ddx58,Stat2,Socs1,Trim12c,Isg15,Ube2l6,Nmi,Ifi208,Wars,Oas2,Maff,Ifit1bl2,Tnfsf10,Plaur,Trafd1,Rnf19b,Herc6,Oas1g,Cxcl10,Optn,Eif2ak2,Rnf114,Il15,Phf11a,Ifi207,Ddx60,Fas,Rtp4,Ifi214,Ifi211,Csf1,Trim14,Trim21,Isg20,Psme2,Tdrd7,Xaf1,Hk1,Lap3,Mndal,Jak2,Ldlr,Vrk2,Max,Dram1,Oasl1,Ifi204,Ifit3b,Stat3,Ifi44,Tlk2,Rsad2,Phf11b,Ifit2,H2-Q6,Oas3,Ifi209,Myd88,Usp18,Ifih1,Psmb10,Parp12,Tap2,Irf7,Cxcl1,Sp110,Tlr3,Cdc42ep4 |
| 5.540e-59 | -134.14 | GO_IMMUNE_RESPONSE | MSigDB lists | GO_IMMUNE_RESPONSE | 916 | 228 | 15632 | 1249 |
Ddx60,Ifi214,P2ry14,Il15,Ifi207,Syk,Ass1,Eif2ak2,Spn,Fcgr2b,Ifnb1,Ptk2,Lyn,Ccl4,Jak2,Nfil3,Ikbkg,Nfkb1,S100a8,Gem,Mndal,Sema3c,Slpi,Csf1,Trim21,Cd74,Cd14,Tnf,Bcl6,H2-Q6,Gbp9,Dhx58,Rsad2,Tlr3,Il2rg,Nfkb2,Vcam1,Ccl5,Fcgr4,Lcp2,Trim26,Cxcl2,Il12rb1,Tlr6,Il4ra,Ccl22,Trim13,Ifna1,Prdx1,Samhd1,Ccl12,H2-Q4,Cx3cr1,Il6,Ccl2,Il18bp,Ebi3,Tnfsf4,Tlr2,Sema4a,Irf1,Igf1r,Clec4n,C1rl,Lcn2,Marco,Il10,Tnfsf14,Pml,H2-Q7,Fgr,Icam1,Nod1,Cst7,Ifnar1,Ifi213,Axl,Ifi205,Swap70,Dennd1b,Dbnl,C1ra,Traf3ip2,Kdm6b,Cd55,Il12b,Clec4d,Clec5a,Tnfsf10,Plcl2,Il1rn,Gch1,Ifit1bl2,Cd86,Tlr1,Tnfsf15,Ifi208,Tyk2,Fas,Cx3cl1,Slamf7,Clec4e,Il27,Zc3hav1,Ppp1r14b,Gsdmd,Nlrc4,Ctsc,Ifna5,Mid1,C3,Oasl1,Tlr9,Ifit3b,Ifi204,Notch2,Tnfrsf1b,Nos2,Rel,Ifi211,Zeb1,Isg20,Trim14,Il18rap,Xaf1,Pou2f2,Trim56,Aim2,Rnf135,Psmb10,Ifih1,Myd88,Batf,Ccl3,Ifna2,Ifit2,Oas3,Ifi209,Ankrd17,Tnfsf8,Ripk2,Nr4a3,Il18,Ikbke,Cxcl1,Il1b,Ccr1,H2-Eb1,Irf7,Osm,Cd274,Tap2,Stxbp3,H2-Aa,Icosl,Bst1,Egr1,Nlrp3,Zbp1,Fcgr1,Adar,Ciita,Tap1,Tnfrsf14,Ifit1bl1,Nlrc5,Prkce,Igsf6,Edn1,Irf4,Irgm2,Cxcl14,Nod2,Stat1,Ifi35,Pik3cd,Mefv,Rgs1,Cd300e,Trem1,Psmb8,Casp4,Itgal,Irf8,Ifit3,Procr,Cysltr2,Ifi203,Rasgrp1,Sirt1,Oas1a,Jag1,Lif,Malt1,Irf2,Trim12c,Isg15,Ddx58,Cd180,Il1a,Stat2,Tnfrsf8,Cd83,Hck,Gbp2,Relb,Notch1,Cd164,Apobec3,Src,Cd40,Pnp2,Gbp4,Ly75,Tapbp,Oas1g,Rnf19b,H2-Ab1,Ptger4,Cxcl10,Serpinb9,Ptafr,Thbs1,Cmklr1,Pf4,Ifna6,Oas2,Csf3 |
| 7.378e-59 | -133.85 | GSE14000_UNSTIM_VS_4H_LPS_DC_DN | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_DN | 172 | 95 | 15632 | 1249 |
Ext1,Tmeff1,Trim26,Ccl5,Plek,Irf7,Cd274,Plat,Il1b,Sp110,Ppp2r2a,Epsti1,Nr4a3,Batf2,Ifi44,Tnc,Ifit2,Oas3,Myd88,Ncoa7,Mcoln2,Nupr1,Ifih1,Kmo,Usp18,Trim21,Isg20,Tdrd7,Xaf1,Ccl4,Oasl1,Ifit3b,Dnajb4,Stap1,Pla2g4a,Parp14,Parp9,Bcl2a1b,Sod2,Eif2ak2,Slamf7,Cd80,Il15,Pim3,Rtp4,Tnfsf15,Ube2l6,Btg2,Oas2,Wars,Gch1,Nampt,Slc31a2,4930523C07Rik,Ifit1bl2,Cnp,Ppm1k,Tnfsf10,Bcl2a1a,Tfec,Trafd1,Cmpk2,Dusp5,Oas1g,Ptger4,Ttc39b,Bcl2a1d,Psmb9,Gbp2,Pml,Irf2,Traf1,Dtx3l,Isg15,Ddx58,Oas1a,Zc3h12c,Ifit3,Tnfaip2,Cflar,Ell2,Casp7,Ifi35,Gpd2,Acsl1,Irf1,Stard5,Nfkbia,Ifit1bl1,Nlrc5,Znfx1,Adar,Pnpt1,Atf3,Nfkbiz |
| 3.387e-58 | -132.33 | regulation of multi-organism process | biological process | GO:0043900 | 621 | 169 | 20694 | 1406 |
Irf1,Oas3,Plau,Hdac1,Slamf8,Tlr9,Nfkbia,Trafd1,H60b,Il10,Parp14,Apobec3,Aim2,Socs1,Eif2ak2,Shfl,Stat5a,Cxcl1,Irf4,Ptpn2,Zfp36,Pde5a,Dtx3l,Irak3,Clec2d,Oas1b,Nr1h3,Nectin2,Ddx60,Trim21,Resf1,Elmod2,Stau1,Ifih1,Lrp8,Il15,Tap2,Nod2,A530064D06Rik,Peli1,Bcl2l11,Smpdl3b,Treml4,Trim26,Nfkbil1,Nmi,Trim12c,Il18rap,Fpr2,Ifi203,Pvr,Oas1a,Arg2,Htra1,Ptafr,Raet1e,Klrk1,Fam111a,Ikbke,Gbp4,Nos2,Wdfy1,Tifa,Ifi208,Mul1,Ripk2,Parp9,Irgm2,Zc3h12a,Fgl2,Il18,Irak2,Optn,Cd300lf,Ifi211,Mndal,Chmp4b,Notch1,Zc3hav1,Gfi1,Stat1,Timp1,Tlr6,Nlrc4,Zbp1,Adar,Ddx58,Clec4e,B430306N03Rik,Tlr2,Inhba,Irf7,Trib1,Tnfaip3,Il12rb1,Irgm1,Myd88,Prdm1,Il27,Rasgrp1,Parp10,Trim56,Pml,Ccr1,Stxbp1,Ccl4,Rnf135,Nlrc5,Cx3cl1,Mapkbp1,Tnf,Oasl1,Mdfic,P2ry2,Ifi204,Jun,Rsad2,Ednrb,Treml2,Cd14,Ifitm1,Ifi214,Il12b,Traf3ip2,Cgas,Tlr1,Cd180,Cd74,Fgr,Ankrd17,Larp1,Ccl5,Trim14,Serpinb9,Tnip3,Nod1,Ifnb1,Plscr1,Spn,Samhd1,Cd86,Isg20,Acvr1b,Slpi,Oasl2,Ifna1,Pik3r6,Dhx58,Il1b,Tap1,Isg15,Lgals9,Trim13,Irf8,Mapkapk2,Acod1,Itgav,Ifi205,Sqstm1,Plat,Tlr3,Trim30a,Ifi209,Prkce,Pcx,Lyn,Cav1,Tnip1,Oas1g |
| 4.240e-58 | -132.11 | GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_DN | MSigDB lists | GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_DN | 194 | 100 | 15632 | 1249 |
Plscr1,Ifi203,Oas1a,P4ha1,Psmb8,Ogfr,Ifit3,Irf8,Ppa1,Stat1,Casp7,Ifi35,Slc25a22,Fam111a,Phf11d,Irf1,H2-Q4,Ifit1bl1,Nfkbia,Dock4,Adar,Samhd1,Phf11c,Tap1,Ifi208,Nmi,Ube2l6,Uba7,Oas2,Wars,Ifit1bl2,Tnfsf10,Trafd1,Plaur,Oas1g,Herc6,Rnf19b,Serpinb9,Tapbpl,Slc15a3,Psma6,Tapbp,C1ra,Casp1,Ifi213,Ifi205,Psmb9,Pml,H2-Q7,Psme1,Isg15,Trim12c,Ddx58,Psme2,Zfp36,Trim21,Isg20,Trim14,Ifi211,Tdrd7,Mndal,Lap3,Casp8,Rbms1,Oasl1,C3,Max,Dram1,Ifit3b,Ifi204,Optn,Rnf114,Gpr18,Phf11a,Ifi207,Fas,Ddx60,Ifi214,Rtp4,Ext1,Parp12,Irf7,Tap2,Cxcl1,Sp110,Parp3,Tlr3,Cdc42ep4,Ifi44,Stat3,Phf11b,Ifit2,Ifi209,Oas3,H2-Q6,Myd88,Cd38,Ifih1,Psmb10,Usp18 |
| 4.868e-58 | -131.97 | positive regulation of immune system process | biological process | GO:0002684 | 877 | 204 | 20694 | 1406 |
Ctsc,Tnfsf9,Cacnb3,Thbs1,Jag1,Il2rg,Acvr1b,Hif1a,Il6,Isg15,Il1b,Mapkapk2,Nr4a3,Prkce,Tnfsf14,Tnfrsf14,H2-T10,Tlr3,Nfkbiz,Ifi205,Fcgr2b,Arid5a,Casp8,Cdkn1a,Myd88,Irgm1,Nck1,Cx3cl1,Kitl,P2ry12,H2-Aa,Nlrc5,Il12b,Cgas,Cd55,Ccdc88b,Cd14,Ifi214,Bcl6,Rgcc,Tnip3,Notch2,Vcam1,Cxcl14,Hcls1,Trim12c,Fpr2,Stat3,H2-Ab1,Egr3,Peli1,Gpr68,Treml4,Ikbke,Ptafr,Cxcl10,Flt1,Usp12,Raet1e,Lif,Klrk1,Nlrp3,Mndal,Zc3hav1,Swap70,Ifi211,H2-Q4,Ddx58,Il12rb1,Inhba,Irf7,Trib1,Nlrc4,Stat1,Lcp2,Tlr6,Crkl,Zbp1,H2-Q6,Ccl2,Pf4,Nfkbia,Tlr9,Fcgr1,Socs1,Ap3b1,Cxcl1,Stat5a,Vegfc,Nr1h3,Fzd5,Hcar2,Il15,Csf1,Dennd1b,Ifih1,Cd86,Adora2b,Plscr1,H2-M2,Spn,Pik3cd,Cd38,Hsph1,Fos,Bcl2a1d,Cd80,Cd274,Cd83,Dhx58,Pik3r6,Axl,Lgals9,Il15ra,Mmp9,Sirt1,H2-T24,Clcf1,C1rl,Ifi209,Il4ra,Tnip1,Cav1,Sell,Lyn,Acod1,Rasgrp1,Ccl12,Ccr1,Ikzf1,Prdm1,Il1a,Ccl3,Ifi204,Tnf,Rsad2,Jun,Stxbp1,Ccl4,Syk,Tlr1,C3,Cd74,Fpr1,Malt1,Pde4b,Rnf31,Icam1,Hk1,Ccl5,Rabgef1,Irs2,Nod1,Cd40,Fgr,Ankrd17,Il18rap,Ptprj,Pvr,Ifi203,Csf3,Icosl,Wdfy1,Irgm2,Tifa,Ifi208,Hlx,Ripk2,Parp9,Traf2,Sele,Il18,Itgal,Zc3h12a,Cd300lf,Irak2,Hmox1,Tlr2,Clec4d,Clec4e,H2-T22,Themis2,Tnfsf4,H60b,Il10,Irf1,Aim2,Bst1,Cmklr1,Ptger4,Nectin2,Ddx60,Mmp14,C1ra,Irak3,Itga4,H2-Q7,Tap2,Nod2,Pla2g7,Nfkbid,Serpine1,Stap1,Edn1 |
| 7.517e-58 | -131.53 | GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP | MSigDB lists | GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP | 183 | 97 | 15632 | 1249 |
Ccnj,Jarid2,Txn1,Nampt,Junb,Arid4a,Daam1,Plk2,Dcbld2,Hcar2,5430427O19Rik,Glrx,Larp1,Smox,Dnaja2,Ptgs2,Chic2,Spata5l1,Ccdc86,Top3a,Rab9,Ccnd1,Mlkl,Birc2,Tank,Nod1,Crlf3,Icam1,Slco3a1,Traf1,Timeless,Hivep3,Ankib1,Birc3,Ubr4,Gbp7,Tnfaip2,Rgs1,Socs7,Socs3,Ppa1,Gpd2,Tmem171,Edn1,Taf4b,Adhfe1,Trmt1l,Zyx,Atf3,Rars,Pde4b,Slc12a9,Csrp1,Map2k1,Irak2,Ppp2r2a,Snn,Keap1,Tlr3,Xkr8,Usp42,Sat1,Ifi44,Hdac1,Tlk2,Mafk,Ythdf1,Armcx6,Ddhd1,Traf2,Arid5a,P2ry13,Ankrd17,Rhbdf2,Cutc,Upp1,Pigv,Tifa,Zfp36,Casp8,Hdc,Polr2g,Mob3c,Dusp16,Wdr43,Rab20,Gsdmd,Spsb1,Hmga1,Ptpn2,Tmem184b,Clec4e,Enpp4,Olr1,Fpr2,P2ry14,Gmppb |
| 8.075e-58 | -131.46 | GSE18281_CORTICAL_VS_MEDULLARY_THYMOCYTE_UP | MSigDB lists | GSE18281_CORTICAL_VS_MEDULLARY_THYMOCYTE_UP | 191 | 99 | 15632 | 1249 |
Gbp3,Ifih1,Psmb10,Cd74,Usp18,F11r,Ch25h,Cd14,Myd88,Arhgef3,Ifit2,Klf6,Tnf,Rsad2,Trib3,St3gal1,Plat,Cxcl1,Gtpbp2,Irf7,Slfn4,Ppp1r15a,Tap2,Dusp6,Ccl5,Cxcl2,Ext1,Gmppb,Klf7,Sqstm1,Gadd45b,Eif2ak2,Ifnb1,Gadd45g,Ctsc,Ifit3b,C3,Jak2,Polr2g,Tnfrsf1b,Slpi,Nfkbib,Csf1,Isg20,Trim21,Isg15,Icam1,Marcksl1,Psme1,Gbp2,Ifit1,Axl,Cebpd,C1ra,Cxcl10,Ptgs2,Rnf19b,Larp1,Glrx,Cmpk2,Trafd1,Plaur,Tnfsf10,Clic4,Il1rn,Slfn3,Plk2,Gch1,Uba7,Wars,Nmi,Phlda1,Ccnd2,Egr1,Atf3,Tap1,Samhd1,Adar,Jun,Znfx1,Fos,Nfkbia,Il18bp,Il4i1,Ccl2,Peli1,Irgm2,Gpd2,Irf1,Ppa1,Stat1,Ifi35,Fam20c,Tnfaip2,Lcn2,Casp4,Ifit3,Psmb8,Ccrl2 |
| 1.527e-57 | -130.82 | GSE22886_CTRL_VS_LPS_24H_DC_DN | MSigDB lists | GSE22886_CTRL_VS_LPS_24H_DC_DN | 188 | 98 | 15632 | 1249 |
Psme2,Isg20,Etv6,Xaf1,Nfkb1,Lap3,Rel,Vrk2,Nfil3,Pim2,Ptgir,Oasl1,Ifit3b,Dusp2,Sqstm1,Sod2,Eif2ak2,Dnaja1,Slamf7,Phf11a,Ddx60,Rtp4,Tbc1d13,Ccl5,Pde4b,Irf7,Ppp1r15a,Nfkb2,Cldnd1,Sp110,Ripk2,Nr4a3,Ifi44,Dhx58,Rsad2,Tlk2,Ifit2,Phf11b,Oas3,Rhbdf2,H2-Q6,Gys1,Tnfaip3,Mvp,Psmb10,Ifih1,Usp18,Rasgrp1,Psmb8,Birc3,Heatr6,Ifit3,Tnip1,Prkar2b,Stat1,Tnfsf4,Ebi3,Ifi35,Casp7,Phf11d,Irf4,Hivep2,Ifit1bl1,H2-Q4,Adar,Phf11c,Tap1,Plagl1,Nmi,Ube2l6,Oas2,Wars,Gch1,Txn1,Ifit1bl2,Samsn1,Cnp,Tnfsf10,Il15ra,Dusp5,Zc3h12a,Ptger4,Herc6,Il12b,Grina,Rab9,Ly75,Casp3,Dusp1,Psmb9,Crlf3,Cd83,Marcksl1,H2-Q7,Traf1,Isg15,Icam1,Ddx58 |
| 3.681e-57 | -129.94 | GSE27859_MACROPHAGE_VS_DC_UP | MSigDB lists | GSE27859_MACROPHAGE_VS_DC_UP | 155 | 89 | 15632 | 1249 |
Ptafr,Spata5l1,Dcbld2,Tcea1,Gca,Daam1,Plk2,Snx10,Calcrl,Slco3a1,Traf1,Marcksl1,Malt1,Hck,Gbp2,Crlf3,Tank,Ifnar1,Slc15a3,Rffl,Pnp2,Irf1,Rcn1,Gpd2,Mefv,Casp7,Kpna3,Denr,Dyrk2,Tagap,Dr1,Cflar,Rnf31,Cd69,Trip13,Nlrp3,Arrdc4,Atf3,St3gal3,Mapkapk2,Cyfip1,Tet2,Hivep2,Rab32,Nod2,Kremen1,Slc44a1,Stard5,Igsf6,Adora2b,Map3k8,Rcl1,Stip1,Ppp2r2a,Irak2,Ikbke,Tap2,Lcp2,Serpine1,Rapgef2,Vasp,Prdm1,Mcoln2,Ccdc88b,Traf2,Csf3r,Rhbdf2,Tnf,Abcc5,Nfkbie,Cers6,B3gnt5,Phgdh,Tnip3,Rab20,Cpeb4,Nfkb1,Ppp1r15b,Etv6,Stxbp1,Spred1,Foxp4,F10,Il27,Sdc4,Nlrc4,Itgav,Vcan,Parp14 |
| 5.550e-57 | -129.53 | GSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_DN | 186 | 97 | 15632 | 1249 |
Tap2,Hopx,Ccl5,Ttc9c,Cdyl,Parp12,Vasp,AA467197,Slc25a12,Il2rg,St7,Prdx5,Cers6,Dock10,Fgl2,Gbp9,Batf2,1110038F14Rik,Psmb10,Gbp3,Cd74,Upp1,Ch25h,1600014C10Rik,Gnb4,Lap3,Il18rap,Psme2,Alas1,Trim21,Cnn3,Asb13,C3,Dram1,Ass1,Sod2,Parp9,Aldh1b1,Fpr2,Usp25,Fas,Evl,Atp11b,Rbl1,Dnase1l3,Hk3,Gpc1,Pilra,Pik3r6,Rnaset2a,Txn1,Tyk2,Inpp5b,Serpinb9,Slamf8,Abcc4,Tfec,Il15ra,Tnfsf10,Gca,Acsl5,Psmb9,Casp1,Insl6,Cst7,Axl,Parp8,Tapbp,Stk40,Zfp800,Gbp4,Dennd1b,Pnp2,Cish,Casp3,Slco3a1,Psme1,Magohb,Cd164,Gbp7,Irf8,Psmb8,Met,Rasgrp1,Smpdl3b,Gpd2,Sema4a,Irf1,Rcn1,Rnaset2b,Tnip1,Il18bp,Irgm2,Edn1,Arrdc4,Samhd1,Tap1 |
| 5.550e-57 | -129.53 | GSE34006_WT_VS_A2AR_KO_TREG_DN | MSigDB lists | GSE34006_WT_VS_A2AR_KO_TREG_DN | 186 | 97 | 15632 | 1249 |
Irgm2,Znfx1,Tap1,Samhd1,Zbp1,Rbm43,Adar,Pnpt1,Ccnd2,Oas1a,Ccrl2,Ifit3,Ogfr,Gbp7,Psmb8,Aida,Irf1,Fam111a,Slc25a22,Etnk1,Ifi35,Casp7,Stat1,Ppa1,Tapbp,Gbp4,Psmb9,Insl6,Apobec3,Daxx,Ifit1,Gbp2,Stat2,Socs1,Isg15,Psme1,Pml,Oas2,Nmi,Noc4l,Lgals9,Gch1,Cmpk2,Trafd1,Slfn3,Tnfsf10,Slfn9,Grina,Cxcl10,Tapbpl,Rnf19b,Oas1g,Vcan,Parp9,Slfn8,Parp14,Tor1aip2,Tmem184b,Morc3,Rnf114,Atp11b,Rtp4,Gmppb,Ddx60,Syne2,Tdrd7,Isg20,Trim21,Psme2,Mov10,Casp8,Lmo4,Tor3a,Pmepa1,Ifit3b,Asb13,Oasl1,Dhx58,Rsad2,Gbp9,Arid5a,Oas3,Mgat1,Ifit2,1600014C10Rik,Usp18,Gbp3,Ifih1,Psmb10,Parp12,Trim26,Slfn4,Cd274,Tor1aip1,Irf7,Keap1,Mitd1 |
| 1.068e-56 | -128.88 | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN | 187 | 97 | 15632 | 1249 |
Pcdh7,Pkp4,Sp110,Tlr3,Ripk2,Rcan1,Parp12,Tap2,Fzd5,Med21,Myd88,Usp18,Ifih1,Psmb10,Ifi44,Rsad2,Phf11b,Ifit2,Arid5a,H2-Q6,Bcl6,Oas3,Jak2,Vrk2,Dram1,Trib1,Ifit3b,Trim21,Trim14,Csf1,Psme2,Xaf1,Tdrd7,Lap3,Sgcb,Il15,Phf11a,Aff1,Zc3hav1,Ddx60,Rtp4,Gclm,Eif2ak2,Rnf114,Dnaja1,Acsl5,Vegfc,Il15ra,Trafd1,Herc6,Rnf19b,Oas1g,Dnaja2,Cxcl10,Ube2l6,Nmi,Wars,Uba7,Oas2,Ifit1bl2,Gch1,Gbp2,Psme1,H2-Q7,Malt1,Irf2,Pml,Stat2,Ddx58,Isg15,Socs1,Slc15a3,Casp1,Psmb9,Tank,Tnfaip2,Casp7,Ifi35,Ppa1,Socs3,Stat1,Irf1,Phf11d,Plscr1,Oas1a,Psmb8,Irf8,Ifit3,Ogfr,Adar,Samhd1,Phf11c,Tap1,Atf3,Rai14,H2-Q4,Ifit1bl1 |
| 2.016e-56 | -128.24 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_DN | 184 | 96 | 15632 | 1249 |
Nfkb2,Ppp2r2a,Ripk2,Atp10a,Nr4a3,4930453N24Rik,Sh3bp4,Ccl5,Brwd3,Atp6v1d,1600014C10Rik,Traf5,Batf,Prrg4,Plk3,Pigv,Gbp9,D1Ertd622e,Aebp2,Fgl2,Treml2,Tpst1,Arid5a,Arhgef3,Arf4,Jak2,Cdkn1a,Max,Tifa,Nfkbib,Ociad1,Casp8,Gem,Rel,Rbl1,Rtp4,Cdk5r1,Aldh1b1,Aftph,Stap1,Tor1aip2,Optn,Gpr18,Trafd1,Zhx2,Hcar2,Fmnl2,Il15ra,Fndc3a,Oas1g,Zc3h12a,Ptgs2,Slc2a6,Wdr59,Igsf8,Sipa1l1,Lad1,Gbp2,Ifit1,Rhoh,Nfkbil1,Mxd1,Isg15,Stat2,Gbp4,Cish,Setdb2,Casp3,Mlkl,Axl,Ehd1,Swap70,Tnip1,Ppa1,Socs3,Tmod3,Dyrk2,Ebi3,Kpna3,Azi2,Eef1e1,Leng9,Oas1a,Casp4,Zbp1,Plagl1,Pttg1,Bbx,Ppfia3,Samd9l,Tra2a,Agrn,Nfkbia,Tiparp,Jun,Znfx1 |
| 3.806e-56 | -127.61 | GSE17721_0.5H_VS_24H_CPG_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_24H_CPG_BMDC_DN | 193 | 98 | 15632 | 1249 |
Slc25a37,Arhgef3,Gbp9,Slc39a4,Cp,Nupr1,Ch25h,Rnf135,Gbp3,Usp18,Zfp281,Sla,Batf,Ccl5,Brd2,Serpine1,Pdgfrb,Asns,Rab10,Tmeff1,Reps1,Fam53c,Ikbke,Pkp4,Aoah,Crbn,Gadd45b,Stap1,Tor1aip2,Parp14,Gclm,Slfn8,Pla2g4a,Ankrd24,Pcx,Slc48a1,Slamf7,Me1,Enpp4,Lmo4,Nos2,Cav1,Slpi,Trim21,Pou2f2,Slamf9,Itga5,Oasl1,Pim2,Dtx2,Mthfd2,Cd82,Jak2,Gsta3,Dusp16,Ppfibp2,Hsph1,Hspa1a,Tank,Acpp,Gbp4,Slc15a3,Rhoq,Lztfl1,Mthfr,Slco3a1,Mdfic,Gbp2,Snx10,Slc13a3,Lad1,Antxr1,Dgka,Rnf19b,Fpr1,Lox,Il12b,Slfn9,Acsl5,Igf2bp2,Vegfc,Agrn,Cx3cr1,Irgm2,Ccnd2,Slc28a2,Tap1,Birc3,Marco,Ampd3,Trip13,Procr,Ell2,Cd200,Ebi3,Hcls1,Tnip1,Rgs1 |
| 7.429e-56 | -126.94 | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_DN | MSigDB lists | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_DN | 186 | 96 | 15632 | 1249 |
Znfx1,Ccl12,Slc7a11,Rnd3,Ccl22,Xrn1,Nfkbiz,Tlr6,Mapkapk2,Ube2e2,Heatr6,Casp4,Gbp7,Birc3,Pfkl,Rcn1,Acsl1,Ebi3,Tnfsf4,Denr,Gsr,Gpr84,Dync1h1,Daxx,Hck,Myo10,Cd83,Fgr,Slco3a1,Magohb,Ier2,Nfkbil1,Itga4,Maff,Phlda1,Asah2,Slc4a7,Jarid2,Junb,Tshz1,Gng12,Tfec,Sec24b,Pim1,Cxcl10,Fpr1,Rnf19b,Traf3ip2,Parp9,Dusp2,Dnaja1,Morc3,Gramd1a,Rnf114,Syk,Sod2,Spred1,Olr1,Mmd,Trim21,Cav1,Jdp2,Rnf14,Ccl4,Ldlr,Lyn,Mtdh,Pim2,Ptgir,Phgdh,Phldb1,Slc16a3,Abcc5,Tnfaip3,Lipg,1600014C10Rik,Fabp3,Ifih1,Ch25h,Aim2,Mmp13,Car13,Vasp,Spint2,Sap30,Gbgt1,Cd274,Hopx,Asns,Gja1,Il1b,Sp110,Ikbke,4930453N24Rik,Adora2b,Gpr85 |
| 1.189e-55 | -126.47 | GSE16755_CTRL_VS_IFNA_TREATED_MAC_DN | MSigDB lists | GSE16755_CTRL_VS_IFNA_TREATED_MAC_DN | 171 | 92 | 15632 | 1249 |
Eif2ak2,Sod2,Rnf114,Fas,Sdc4,Il15,Zc3hav1,Sema3c,Lap3,Trim21,Ppp4r2,Trim56,Rictor,Tdrd7,Tnip3,Lyn,Jak2,Dusp16,Cdkn1a,Oas3,Ifi44,Rnf24,Batf2,Dhx58,Mcoln2,Ifih1,Sav1,Myd88,Cd38,Ncoa7,Plagl2,Cd274,Trim26,Parp12,Atp10a,Osgin2,4930453N24Rik,Cdc42ep4,Vcam1,Sp110,Ppp2r2a,Nlrc5,Hivep2,Nfkbia,Agrn,Il6,Peli1,Gpr35,Samd9l,Rbm43,Abtb2,Psmb8,Pdss1,Jag1,Stat4,Dcp1a,Ifi35,Ebi3,Socs3,Ell2,Acvr1b,Irf1,Src,N4bp1,Psmb9,Cd40,Psma6,Pml,Stat2,Ddx58,Icam1,Isg15,Dtx3l,Traf1,Gbp2,Slc31a2,4930523C07Rik,Ppm1k,Nmi,Slc2a6,Stx11,Herc6,Rnf19b,Zc3h12a,Dusp5,Ptgs2,Serpinb9,Cxcl10,Serpinb2,Tnfsf10,Trafd1,Cmpk2 |
| 2.699e-55 | -125.65 | GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_UP | 184 | 95 | 15632 | 1249 |
Cmpk2,Trafd1,Slfn9,Tnfsf10,Bcl2a1a,Dek,Serpinb9,Ttc39b,Cxcl10,Oas1g,Herc6,Larp1,Oas2,Hap1,G3bp2,Rilpl1,Cd86,Ifit1bl2,Nampt,Gbp2,Ifit1,Daxx,Isg15,Dtx3l,Spata13,Ddx58,Pml,Bcl2a1d,Gbp4,Setdb2,Gypc,Axl,Aida,Irf1,Ppa1,Stat1,Ccdc25,Ccrl2,Oas1a,Gbp7,Abtb2,Vcpip1,Samhd1,Pnpt1,Zbp1,Phip,Samd9l,Peli1,Tet2,Agrn,Ifit1bl1,Nlrc5,Epsti1,Inpp1,Cldnd1,Mitd1,Cox18,Tlr3,Parp12,Irf7,Cd274,Ncoa7,Ifih1,Usp18,Rsad2,Ogfrl1,Gbp9,Ifi44,Oas3,Ifit2,Pmepa1,Idi1,Lyn,Asb13,Parp11,Oasl1,Mtdh,Xaf1,Tdrd7,Zscan29,Isg20,Trim21,Sco1,Tor3a,Slfn5,Sgcb,Rtp4,Usp25,Ddx60,Parp9,Parp14,Slfn8,Bcl2a1b,Plac8,Eif2ak2 |
| 3.809e-55 | -125.30 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_DN | 165 | 90 | 15632 | 1249 |
Otud1,Sp140,Rab9,Isg15,Dtx3l,Traf1,Trim12c,Stat2,Ddx58,Pml,Mxd1,Irf2,Cnp,Gch1,Ifit1bl2,Slc31a2,Nampt,Stx11,Oas2,Wars,Tnfsf15,Ptgs2,Dusp5,Herc6,Cmpk2,Il15ra,Slfn9,Tnfsf10,Snapc1,Znfx1,Nlrc5,Ifit1bl1,Samd9l,Il6,Stard5,Tap1,Phf11c,Adar,Pnpt1,Zbp1,Ifit3,Zc3h12c,Irf8,Abtb2,Dcp1a,Plscr1,Tlr2,Irf1,Phf11d,Oas3,Arid5a,Tnf,Phf11b,Ifit2,Dhx58,Tlk2,Ifi44,Batf2,Stat3,Ifih1,Gbp3,Usp18,Csrnp1,Aim2,Tnfaip3,Ncoa7,Plekha4,Cd274,Pde4b,Arl5b,Trim26,Map3k8,Usp42,Pcgf5,Ripk2,Atp10a,Epsti1,D16Ertd472e,Phactr4,Parp14,Slfn8,Rtp4,Fas,Ddx60,Cd80,Phf11a,Xaf1,Lyn,Ifit3b,Oasl1 |
| 4.083e-55 | -125.24 | HALLMARK_INTERFERON_ALPHA_RESPONSE | MSigDB lists | HALLMARK_INTERFERON_ALPHA_RESPONSE | 89 | 67 | 15632 | 1249 |
Epsti1,Trafd1,Sp110,Cmpk2,Herc6,Oas1g,Ripk2,Cxcl10,Trim26,Ube2l6,Nmi,Wars,Parp12,Uba7,Cnp,Irf7,Ncoa7,Gbp2,Irf2,Psme1,Cd74,Stat2,Usp18,Isg15,Ifih1,Trim12c,Sell,Gbp3,Ifi44,Batf2,Dhx58,Rsad2,Ifit2,Casp1,Psmb9,Ifi35,Oasl1,Irf1,Ifit3b,Trim21,Trim14,Isg20,Procr,Csf1,Psme2,Plscr1,Ccrl2,Oas1a,Tdrd7,Psmb8,Rnf31,Mov10,Ifit3,Lap3,Ogfr,Casp8,Il15,Adar,Pnpt1,Tap1,Ddx60,Il4ra,Rtp4,Parp14,Parp9,Samd9l,Eif2ak2 |
| 4.740e-55 | -125.09 | innate immune response | biological process | GO:0045087 | 534 | 152 | 20694 | 1406 |
Aim2,Eif2ak2,Ccl7,Shfl,Trim12a,Apobec3,Gbp7,Iigp1,Mcoln2,Herc6,Ifit3,Tnfsf4,Cx3cr1,S100a8,H60b,Parp14,Irf1,Ccl2,Oas3,Cdc42ep4,Ppp1r14b,Fcgr1,Gbp2,Tlr9,Evl,Csf1,H2-Q7,Nod2,Trim21,Tgtp1,Sp110,Ifih1,Ccl9,C1ra,Rnf19b,Ccl8,Dtx3l,Gbp4,Ikbke,Nos2,Tifa,Parp9,Ripk2,Irgm2,Arg2,Raet1e,Klrk1,Gbp3,Nmi,Stx11,Lcn2,Casp1,Stat2,H2-Ab1,Clec5a,Hck,Cdc42ep2,Smpdl3b,Treml4,Casp4,Trim26,Ddx58,Adar,Clec4e,Tlr2,Clec4d,Irf7,Il12rb1,Mx2,Tarm1,Stat1,Jak2,Tlr6,Nlrc4,Mx1,Marco,Zbp1,Flnb,Nlrp3,Zc3hav1,Slamf7,Il18,Optn,Clec4n,Cx3cl1,Oasl1,Ccl3,Rsad2,Ccl4,Stxbp1,Gbp9,Rnf135,Nlrc5,Syk,H2-Aa,Gch1,Arid5a,Ccl12,Zyx,Trim56,Pml,Rab20,Irgm1,Myd88,Prdx1,Prdm1,Il27,Trim14,Ccl5,Nod1,Ifnb1,Stxbp3,Fgr,Ankrd17,Gbp8,Il12b,Cgas,Tlr1,Mefv,C3,Cd180,Cd55,Malt1,Gsdmd,Cd14,Ifitm1,Oas2,Ciita,Ifit2,Oasl2,G3bp2,Ifit1,Gbp2b,H2-Eb1,Slpi,Samhd1,Isg20,Pik3cd,C1rl,Trim30a,Lyn,Tnfrsf14,Acod1,Ifnar1,Tlr3,Dhx58,Isg15,Trim13,Irf8,Axl,Ifna1,Ccl22 |
| 5.137e-55 | -125.01 | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_DN | MSigDB lists | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_DN | 185 | 95 | 15632 | 1249 |
Cdkn2d,Il15,Sgcb,Aff1,Tle3,Ahr,Pla2g4a,Fcgr2b,Gclm,Tor1aip2,Vcan,Gadd45g,Lyn,Jak2,Ccl4,Dusp16,Tor3a,Nfkb1,Zfp36,Ch25h,Mcoln2,Zfp281,Usp18,Gbp3,Ifih1,Myd88,Rnf34,Apaf1,Ifit2,Txnrd1,Arhgef3,Ankrd17,Tpst1,Stat3,D1Ertd622e,Fgl2,Pcgf5,Nr4a3,Map3k8,Gcnt2,Cldnd1,Ccr1,Gja1,Lcp2,Rars,Nfkbiz,Il4ra,Pnpt1,Fcgr1,Chmp4b,Tap1,Nfkbia,Ccl12,Znfx1,Tiparp,Jun,Irgm2,Peli1,Ccl2,Ifi35,Etnk1,Il13ra1,Dck,Irf1,Ier3,Dr1,Irf8,Gbp7,Casp4,Plscr1,Pml,Socs1,Isg15,Cd83,Gbp2,Casp1,Timp1,Psmb9,Slc2a1,Nr3c1,Pnp2,Cebpd,Rnf19b,Larp1,Fndc3a,Pim1,Tgfbi,Cxcl10,Trafd1,Nampt,Gch1,Lgals9,Cd86,Inpp5b,Hk2 |
| 9.533e-55 | -124.39 | protein binding | molecular function | GO:0005515 | 8786 | 888 | 20217 | 1400 |
Gpsm2,Nr1h3,Gja1,Cd34,Socs1,Ddx4,Spen,Caml,Nod2,Csf1,Lyn,Ier3,Adgrg6,Ifit1,Bcl2a1a,Ksr1,Cd86,Ifi205,Rims3,Cx3cl1,Sipa1l1,Mvp,Cd274,Msantd3,Slc16a1,Atp2b4,Ccl12,Kif5c,Mx1,Stat2,Rras2,Nmral1,Ccdc88b,Zc3hav1,Slfn1,Lcn2,Ahr,Tpx2,H60b,Il2rg,Tnip3,Mier3,Axl,Ntng2,Riox2,Crkl,Il15,Cebpd,H2-T22,Ppp1r12b,Srgn,Angpt1,Mdm2,Asah2,Trim36,Hsph1,Pde1b,Mafk,Atm,Prdm1,Kdr,Il12rb1,Clcn5,Vegfc,Sqstm1,Myo10,Dach1,Myd88,Srm,Nr4a3,Tmem178,Eif4g2,Eva1b,Nfkb2,Tmod3,Eya4,Flnb,Txnrd1,Tomm70a,Igsf9,Clcf1,Smpdl3b,Cnn3,Klf7,Ctsc,Isg15,Vcam1,Ppp2r5a,Insl6,Cdyl2,Prag1,Phlda1,Tmem176a,Ptafr,Olr1,Htr2a,Mcm10,Clec4d,H2-T10,Hspa1a,Hk3,Btg2,Ifi209,Tarm1,Tapbp,Ccl5,Tnc,Adam19,Tlr3,Ezr,Kdm4a,Gng11,Rsad2,Tab2,Tor1aip1,Mecp2,Procr,Tfec,Zbp1,Sbds,C3,Pilrb1,Pml,Hinfp,Plaur,Rel,Lcp2,Cdyl,Pim3,Tnfrsf1b,Kif3c,Odc1,Kcnj2,Cdkn1a,Psd,Gpc1,Pdgfrb,Slc39a13,Eno1,Eif2ak2,Hk1,Hdac1,Dync1h1,Mapkbp1,Cd38,Dgkh,Keap1,Dtx3l,Vrk2,Oas1a,Ppp6r1,Gbp2,Dtx2,Prdx1,Fos,Rhoh,Cd200,Psme1,Dennd6b,Casp8,Daxx,Pf4,Psd4,Slamf8,Cyth3,Hp,Il27,Bcl2l11,Ranbp2,Tgs1,Il1a,Ifi207,Rhoc,Arhgap26,Ift57,Ktn1,Ddx60,Il6,Slc9a1,Milr1,Junb,Saa3,Ddx58,Tuba4a,Nfil3,Hcls1,Clec4e,Ets2,Phactr4,Fbxo4,Pdgfc,A530064D06Rik,Tlr9,Ccnd2,Rhof,Hmgcs1,Dr1,Atf3,Sema3c,Rasgrp1,Cited2,Mtdh,Plk2,Nr4a1,Sik3,Dnaja2,Sirt1,Tax1bp1,Trip13,Dync1i2,Lrp8,Optn,Azi2,Esd,Pik3r6,Chmp4b,Rgl1,Gfi1,Ccl4,Sod2,Cenpe,Inhba,Slpi,Sinhcaf,Lpar1,Spn,Treml4,H2-Aa,Rac3,Mmp13,Il1b,Nectin4,Ifi203,Dnajb2,Ldha,Samsn1,Antxr1,Cdkn2d,Gadd45b,Fcgr2b,Xcr1,Kdm6b,P2ry2,Etv3,Rnf135,Gk,Abr,Kpna3,Uchl1,Slc25a12,Mllt6,Gbp2b,Il4ra,Ifi211,Nlgn2,Casp4,Rab3ip,Raet1e,Samd9l,Nfkb1,Snx10,Tle3,Ccne1,Tyk2,Icam1,Fpr2,Pkp4,Rbpms,Dcun1d3,Ripk2,Tnfsf14,Cgas,Plpp3,Cd40,Golga3,Pdlim7,Ciita,Mul1,Tlr2,Pilra,Birc2,Ubr4,Parp10,Tnfsf10,Gdf15,Sh3bp4,Il1rn,Piezo1,Psmd10,Rnf19a,Pfkl,Cxcl10,Map3k6,Rgcc,Rbl1,Scarf1,Plk3,Rab11fip1,Dusp16,Nlrc4,Rsbn1,Fpr1,Apobec3,Ccng2,Kat2b,Apba1,Thbs1,Timeless,Brd2,Pdpn,Ccrl2,Jag1,Dnaja1,Cacna1d,Mlkl,Pilrb2,Pcx,Rhbdf2,Slc4a7,Htr2b,Lnpk,Gda,Uaca,Cx3cr1,Dnajb4,Itgb8,Bambi,H2-Q6,Rab32,Klf2,Ccnj,Glrx,Irf8,Hmga2,Pvr,Ptgs2,Zc3h12a,Rpgrip1l,Zhx2,Relb,Grk3,Cacnb3,Ccnd1,Trib1,Plscr1,Bfar,Sema4c,Ahsa1,Nxf1,Irgm2,Gna15,Mark2,Gem,Rhou,Tlr6,Irf1,Tagap,Slamf7,Bcl2a1d,Timp1,Mov10,Jmjd6,Siglece,Syk,Cnn2,Mcm6,Plek,Fgr,Cd300lf,Asns,Sertad3,Ikbkg,Met,Mcm9,Cep350,Tap2,Tent2,Cdk5r1,Edn1,Cdc42ep4,S100a8,Sgcb,Ass1,Il15ra,Jdp2,Scn1b,Fscn1,Ifnb1,Osgin2,Ccl8,Hsd17b7,Rnf14,Kdm5b,Psme2,Stxbp3,Fcgr1,Cish,Irak2,Lhx2,Rnf34,Acvr1,Palld,Hif1a,Gadd45g,Tnfsf4,Syne2,Fzd5,Pcgf5,Sh3bgrl2,Pdgfb,Vasn,Samhd1,Nlrp3,Ifna4,Nfkbie,Klrk1,Casp3,Agrn,Phf6,Fchsd2,Ltbp2,Ppp2r2a,Rab9,Tshz1,Zfp281,Irs2,Daam1,Carhsp1,Hopx,Notch2,Tagln,Katna1,Rgs1,Rtp4,Max,Prkce,Prdx5,Tnfsf15,Tmem67,Casp7,Cp,Flrt3,Ikzf1,Sap30,Mmp14,Themis2,Ahrr,Ptk2,Ext1,Ifna6,Trem1,Gca,Sell,Acvr1b,Lrp4,Hdc,Il18bp,Cop1,Mid1,Pdzd11,Myc,Mx2,Stat3,Cxcl1,Sla,Hmox1,Psip1,Slc2a1,Rcan1,F11r,Dck,Triobp,Hilpda,Itga5,Csf3r,Rcsd1,Marcks,Plat,Nck1,Acpp,Trib3,Dtnb,Ccl3,Znrf3,Dusp2,Lnpep,Glipr2,Gbp4,D16Ertd472e,Dio2,Dusp6,Birc3,Fzd1,Ehd1,Sav1,Kitl,Mthfd1l,Znrf1,Irak3,Peli1,Gtpbp2,Tlr1,Hmga1,Diaph2,Traf1,Casp1,Nampt,Gclm,H2-Ab1,Tbc1d1,Ralgds,Cxcl11,Ankib1,Rgs14,Ifi204,Ifna1,Agtrap,Tsku,Kctd12,Tspo,Rapgef5,Stip1,Myo1b,Fmnl2,Ppp1r15a,Lrch1,Aftph,Egr1,Hk2,Tal2,Usp18,Tgfbi,Malt1,Tnfrsf14,Mndal,Ednrb,Ebi3,Ly6a,Mitd1,Pde3b,Tifa,Etv6,Dst,Sdc1,Nox1,Frmd4a,Serpinb9b,Stat5a,Fubp1,Rhoq,Cxcl2,Cd80,Arhgef3,Itpkc,Dock10,P4ha2,Gng12,Rab21,Frmd6,Traf2,Tmem176b,Usp25,Apaf1,Gclc,Ppfibp2,Ankrd24,Pmaip1,Wars,Aim2,Clic4,Sele,Whamm,Pid1,Stap1,Mapkapk2,Fcho2,Adar,Tor1aip2,Ripk3,Cpd,Tnfaip2,N4bp1,Itga9,Hap1,Prnp,Stra6l,Jak2,Spire1,Traf3ip2,Anp32a,Cyfip1,Rilpl1,Rictor,Cxcl3,Lmo4,Snx2,Pcdh7,Ap3b1,Tap1,Ccl7,Spsb1,Dusp1,Bcl6,Jarid2,Polr2g,Asf1a,Gbp3,Nfkbiz,Ptch1,Stx6,Il18,Rabgef1,Usp53,Mycl,Spred3,Pou2f2,Lif,Nqo1,Clec4n,Plac8,Sat1,Dennd1b,Ddit4,Cycs,Bnip3,Trim56,Cd180,Hspa1b,Htra1,Nr3c1,Pim1,Casp2,Stk40,Ifi213,Ptprj,Zyx,Homer1,Nfkbib,Cacybp,Itgav,Larp1,Nmi,Trafd1,Tnfsf8,Ggct,Stx11,Nos2,Lgals9,Noct,Tor3a,Lrp11,Spata13,Gys1,Marcksl1,Dmxl2,Socs7,Slc31a1,Trip10,Gsr,H2-Q7,Ifnar1,Tpm4,Nrp2,Bmp2,Nectin2,Cav1,Eef1e1,Rnf19b,Igsf8,Me1,Ifit3b,Bcor,Smg7,Il10,H2-M2,Cd200r4,Cxcl9,Mdfic,Nfkbid,Sec24b,Rnf31,Pikfyve,Icosl,Abtb2,Ncoa7,Cd164,Aida,Osm,Egr2,Marco,Rrs1,Tnks1bp1,Hsd17b12,Sesn3,Iigp1,Sdc4,Crlf3,Ifna2,Igf1r,Nfkbia,Stat1,Crim1,Ctla2b,Itpr1,Hspa2,Src,Med13,Il12b,Hat1,Pmepa1,Evl,Fut8,Ccl22,Sema4a,Fas,Swap70,Pbx1,Cxcl14,Svbp,Pik3cd,Plekha2,Tpi1,Mafg,Vps54,Stau1,Vasp,Ppm1l,Sp100,Zeb1,Traf5,Rffl,Clcn7,Dennd2a,Socs3,Stxbp1,Cst7,Ube2l6,Herc6,Ppp2r3a,Ifi208,Serpine1,Tnfaip3,Arf4,Tbc1d13,Acvrl1,Wdfy1,Txn1,Ikbke,Micall2,Ociad1,P4ha1,Ppp4r2,Spred1,Cenpj,Rnd1,Bcl2a1b,Alas1,Ifrd1,Map2k1,Tcea1,Rnd3,Plagl1,Nes,Csrp1,Mtus1,Nsmaf,Arid5a,Mpp7,Nek6,Arg2,Pde4b,S1pr2,Ep400,Dek,Tdrd7,Ptpn2,Phyh,Pla2g4a,Cflar,Bcl9,Adrb2,Pdss1,Taf4b,Med21,Cd74,Actb,Il13ra1,Kmt5a,Acp2,Grina,Hhex,Tcf4,Zmynd15,Tulp3,Sdc2,Irf4,Resf1,Gch1,Dock4,Kif9,Eno2,Ppp2r1b,Cd69,Vcan,Pim2,Tnf,Ciapin1,Tank,Vezt,Ccr1,Lox,Plcl2,Clec2d,Ifih1,Mefv,Map2k4,Itgal,Parp9,Ric1,Xrn1,Tra2a,Hck,Phip,Pstpip2,Irf7,Tnfsf9,Nupr1,H2-Q4,Mmp9,Serpinb9,Ccl9,Nod1,Itga4,Pttg1,Psma6,Rnf139,Mxd1,Rapgef2,Arrdc4,Tnip1,Plau,Cdc42ep2,Ifi214,Rrbp1,Clec5a,Ccl2,Batf,Hvcn1,Rbbp8,Ldlr,Stat4,Akt3,Scyl2,Prkar2b,Ubash3b,Tpst1,Gng4,Rab10,H2-Eb1,Map4k4,Dcp1a,H2-T24,Adgrl2,Sphk1,Ifit3,Jun,Dbnl,Ifna5,Zfp36,Flt1,Lztfl1,Trim12c,Scimp,Notch1,Trim21,Errfi1,Foxp4,Ccr3,Fabp3,Slc31a2,Lipe,Tmsb10,Parp14,Spry2,Csf3,Adora2a,Flrt2,Reps1 |
| 1.648e-54 | -123.84 | GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_DN | MSigDB lists | GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_DN | 195 | 97 | 15632 | 1249 |
Fam111a,Slc25a22,Irf1,Phf11d,Stat1,Ifi35,Casp7,Ifi203,Oas1a,Plscr1,Casp4,Ogfr,Ifit3,Irf8,Psmb8,Samhd1,Tap1,Phf11c,Adar,Rars,Dock4,Ifit1bl1,H2-Q4,Trafd1,Plaur,Tapbpl,Oas1g,Rnf19b,Uba7,Oas2,Wars,Ifi208,Nmi,Ube2l6,Gch1,Ifit1bl2,Nampt,Gbp2,Isg15,Ddx58,Pml,H2-Q7,Psme1,Tapbp,Psma6,C1ra,Ifi205,Psmb9,Casp1,Ifi213,Jak2,Ifit3b,Ifi204,Oasl1,C3,Dram1,Max,Psme2,Zfp36,Isg20,Trim14,Trim21,Ifi211,Lap3,Mndal,Casp8,Tnfrsf1b,Ifi207,Phf11a,Ifi214,Rtp4,Fas,Ddx60,Optn,Ctsc,Sod2,Rnf114,Sp110,Cxcl1,Cdc42ep4,Ripk2,Parp3,Tlr3,Parp12,Tap2,Cd38,Myd88,Ifih1,Psmb10,Cd74,Ifi44,Sat1,Stat3,Ifi209,Oas3,H2-Q6,Phf11b |
| 1.831e-54 | -123.73 | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_DN | MSigDB lists | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_DN | 187 | 95 | 15632 | 1249 |
Tnfrsf1b,Oasl1,Rcsd1,Idi1,Cd82,Clcn7,Dusp16,Rapgef5,Syk,Ptpn2,Optn,Bcor,Fas,Tmem176b,Nr1h3,Papss2,Slamf7,Il15,Dusp14,Spred1,Foxp4,Ccl5,Irf7,Arl5b,Nrp2,Gpr132,Mmp13,Car13,Ripk2,St3gal1,Map3k8,Nr4a3,Adora2b,Osgin2,Ikbke,Pcdh7,Ankrd17,Rhbdf2,Ubtd2,Itgb8,Slc39a4,Cdyl2,Prdm1,Gbp3,Arg2,Fam133b,Atp11a,Ube2f,Rnf34,Batf,Irak3,Hvcn1,Ncoa7,Clec4n,Casp4,Il10,Procr,Rnf19a,Socs3,Cd200,Ebi3,Tnfaip2,Clcf1,Agpat4,Sbds,Cx3cr1,Rhof,Znfx1,Pdpn,Ncoa5,Sgms2,Nampt,Junb,Slc7a2,Lad1,Adora2a,Csf3,Dusp5,Slamf8,Serpinb2,N4bp1,Ifnar1,Hspa1a,Slc2a1,Tank,Swap70,Slc15a3,Setdb2,Stk40,Zfp513,Psme1,Calcrl,Spata13,Gbp2,Daxx |
| 3.328e-54 | -123.14 | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN | 172 | 91 | 15632 | 1249 |
Ifit1bl1,Nlrc5,Nfkbiz,Atf3,Pnpt1,Birc3,Zc3h12c,Ifit3,Oas1a,Dcp1a,Casp7,Stat1,Socs3,Irf1,Gpd2,Acsl1,Cflar,Bcl2a1d,Ddx58,Traf1,Dtx3l,Isg15,Bmp2,Gbp2,Nampt,Slc31a2,Ifit1bl2,Gch1,Ppm1k,Cnp,Ube2l6,Tnfsf15,Wars,Oas2,Stx11,Ptger4,Herc6,Dusp5,Oas1g,Ttc39b,Bcl2a1a,Tnfsf10,Il15ra,Vegfc,Cmpk2,Sod2,Bcl2a1b,Parp9,Usp25,Rtp4,Il15,Slamf7,Cd80,Slfn5,Isg20,Trim56,Xaf1,Dram1,Oasl1,Ifit3b,Mthfd2,Ccl4,Ifit2,Homer1,Batf2,Ifi44,Itgb8,Errfi1,Rsad2,Aim2,Mcoln2,Nupr1,Usp18,Ifih1,Myd88,Ncoa7,Cd38,Ccl5,Cd274,Irf7,Osm,Trim26,Car13,Atp10a,Usp42,Nr4a3,Plat,Irak2,Epsti1,Il1b,Sp110 |
| 3.486e-54 | -123.09 | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | 176 | 92 | 15632 | 1249 |
Marcksl1,Malt1,Calcrl,Icam1,N4bp1,Ehd1,Dusp1,Tank,Rbbp8,Cebpd,Zfp800,Lztfl1,Rnf19b,Kif3c,Ak4,Hcar2,Gch1,Snx10,Samsn1,Maff,Csf3,Mapkapk2,Nfkbiz,Nlrp3,Trim13,Pik3r5,Nfkbia,Rab32,Stard5,Socs3,Kpna3,Gpd2,Tlr2,Tnip1,Tnfaip2,Cflar,Gfi1,Birc3,Abtb2,Zc3h12c,Trip13,Leng9,Cd69,Rasgrp1,Slc39a14,Rnf19a,Ch25h,Ccdc88b,Batf,Irak3,Tnfaip3,Zswim4,Tnf,Rhbdf2,Itgb8,Rab11fip1,Nfkbie,St3gal1,Adora2b,Osgin2,Irak2,Nfkb2,Ralgds,Cdyl,Pde4b,Plek,Lcp2,Reps1,Icosl,Fzd1,Vasp,Sh3bp4,Nck1,Olr1,Foxp4,Klf7,Spred1,Syk,Ets2,Spic,Ift57,Cpeb4,Rab20,Ccl4,Fam102b,Hsd17b7,Lrrc8c,Dusp16,Nfkb1,Rel,Nfkbib,Rictor |
| 4.361e-53 | -120.56 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_DN | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_DN | 149 | 84 | 15632 | 1249 |
Xaf1,Plscr1,Isg20,Ifit3,Abtb2,Fam111a,Ifit3b,Phf11d,Stat1,Oasl1,Samd9l,Phactr4,Ifnb1,Parp9,Mmp14,Il6,Stard5,Kcnj2,Parp14,D16Ertd472e,Znfx1,Hivep2,Fam43a,Gadd45b,Phf11c,Zc3hav1,Tap1,Slfn5,Zbp1,Adar,Pnpt1,Phf11a,Extl2,Rtp4,Nfkbiz,Ddx60,Fas,Oas2,Uba7,Stx11,Wars,Arl5b,Trim26,Irf7,Cnp,Gch1,Slc31a2,Pde4b,Rgl1,Cmpk2,Sp110,Epsti1,Il15ra,Tnfsf10,Cxcl10,Map3k8,Ptgs2,Atp10a,Naa25,Tlr3,Herc6,Dhx58,Rsad2,Tlk2,Batf2,Ifi44,Oas3,Arid5a,Phf11b,Ifit2,Tnf,Cd38,Myd88,Gbp3,Trim12c,Ifih1,Isg15,Dtx3l,Ddx58,Stat2,Usp18,Pml,Aim2,Ier2 |
| 7.821e-53 | -119.98 | regulation of response to biotic stimulus | biological process | GO:0002831 | 363 | 122 | 20694 | 1406 |
Il27,Prdm1,Irgm1,Myd88,Pml,Ccr1,Rasgrp1,Rnf135,Nlrc5,Rsad2,Cx3cl1,Mapkbp1,Tnf,Ifi204,Ifi214,Treml2,Cd14,Cd180,Cd74,Il12b,Cgas,Traf3ip2,Tlr1,Fgr,Ankrd17,Nod1,Ccl5,Serpinb9,Tnip3,Spn,Plscr1,Samhd1,Cd86,Ifna1,Lgals9,Mapkapk2,Dhx58,Il1b,Pik3r6,Cd274,Tap1,Ifi205,Tlr3,Acod1,Cav1,Lyn,Tnip1,Trim30a,Ifi209,Prkce,Slamf8,Tlr9,Nfkbia,Irf1,H60b,Parp14,Trafd1,Apobec3,Cxcl1,Stat5a,Aim2,Socs1,Dtx3l,Irak3,Irf4,Ptpn2,Ddx60,Clec2d,Nectin2,Nr1h3,Ifih1,Elmod2,Nod2,A530064D06Rik,Lrp8,Il15,Tap2,Smpdl3b,Treml4,Nfkbil1,Peli1,Pvr,Ifi203,Fpr2,Trim12c,Nmi,Il18rap,Raet1e,Klrk1,Arg2,Htra1,Tifa,Ifi208,Parp9,Mul1,Ripk2,Irgm2,Gbp4,Ikbke,Wdfy1,Optn,Irak2,Cd300lf,Ifi211,Zc3h12a,Fgl2,Zc3hav1,Gfi1,Mndal,Zbp1,Stat1,Tlr6,Nlrc4,Tnfaip3,Irf7,Trib1,Il12rb1,Ddx58,Adar,Clec4e,B430306N03Rik,Tlr2 |
| 1.567e-52 | -119.29 | GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP | 166 | 88 | 15632 | 1249 |
Cd274,Ppp1r15a,Plek,Pde4b,Cxcl2,Inhba,Rapgef2,Arl5b,Ddit4,Nr4a3,Map3k8,Il18,Ripk2,Il1b,Cxcl1,Stat5a,Tnf,Errfi1,Rab21,Rnd1,Csrnp1,Plk3,Tnfaip3,Sav1,Rel,Ppp1r15b,Dcun1d3,Nfkb1,Usp12,Tifa,Dnajb4,Tnip3,Egr3,Ccl4,Trip10,Ets2,Bcl2a1b,Sod2,Gadd45b,Nr4a1,Gramd1a,Dusp2,Sdc4,Pim3,Gch1,Txn1,Maff,Csf3,Scn1b,Btg2,Ptgs2,Zc3h12a,Dusp5,Ptger4,Plaur,Bcl2a1a,Rbbp8,Otud1,Plekhf2,Dusp1,Bcl2a1d,Gpr84,Icam1,Il1a,Rhoh,Gbp2,Cd83,Il10,Birc3,Ccrl2,Pdss1,Acsl1,Ier3,Socs3,Ell2,Rgs1,Clcf1,Cflar,Jun,Nfkbia,Hivep2,Peli1,Il6,Edn1,Nlrp3,Egr1,Nfkbiz,Pfkfb3 |
| 3.067e-52 | -118.61 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN | 167 | 88 | 15632 | 1249 |
Ddx60,Ifi214,Rtp4,Phf11a,Ifi207,Zc3hav1,Eif2ak2,Parp14,Parp9,Oasl1,Parp11,Ifi204,Ifit3b,Mov10,Mndal,Lap3,Casp8,Isg20,Trim21,Ifi211,Trim56,Xaf1,Aim2,Csrnp1,Usp18,Ifih1,Myd88,Ifit2,Phf11b,Ifi209,Oas3,Ifi44,Batf2,Rsad2,Dhx58,Atp10a,Usp42,Ikbke,Epsti1,Sp110,Cd274,Irf7,Il12rb1,Xrn1,Adar,Pnpt1,Zbp1,Phf11c,Tap1,Ifit1bl1,Nlrc5,Znfx1,Stard5,Samd9l,Stat1,Phf11d,Irf1,Tagap,Ifit3,Plscr1,Oas1a,Ifi203,Pml,Stat2,Ddx58,Isg15,Dtx3l,Trim12c,Socs1,Ifi213,Ifi205,Herc6,Oas1g,Cxcl10,Tnfsf10,Il15ra,Cmpk2,Trafd1,Rgl1,Ifit1bl2,Slc31a2,Gch1,Cnp,Ifi208,Wars,Stoml1,Uba7,Oas2 |
| 5.654e-52 | -118.00 | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP | MSigDB lists | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP | 184 | 92 | 15632 | 1249 |
Ube2f,Sav1,Nupr1,Lrch3,Ifih1,Tab2,Rab21,Prdx5,Ythdf1,Tlk2,Rhbdf2,Arid5a,Pilrb1,Snn,Acp2,Rcl1,Hp,St3gal1,Nr4a3,Usp42,Vasp,Hsd17b12,Rrs1,F10,Pilrb2,Zc3hav1,Enpp4,Stxbp1,P2ry14,Gmppb,Stap1,Slfn8,Rnf114,Bcl2a1b,Tmem184b,Idi1,Fscn1,Pmepa1,Pim2,Dtx2,Rab20,Srxn1,Usp12,Ppp1r15b,Hdc,Mov10,Rhoc,Myo10,Agtrap,Icam1,Slc15a3,Tapbp,Bcl2a1d,Mdm2,Dusp1,Ehd1,Acpp,Slfn9,Bcl2a1a,Il15ra,Kdm6b,Larp1,Spata5l1,Maff,Tshz1,Ccnj,Samsn1,Lad1,Chmp4b,Rars,Nlrp3,Ccl22,Peli1,Tmem171,Triobp,Tspan3,Hcls1,Tnip1,Ap3m2,Trem1,Dyrk2,Ell2,Stat1,Casp7,Azi2,Irf1,Cd69,Rasgrp1,Psmb8,Ogfr,Il10,Itgal |
| 6.104e-52 | -117.93 | GO_DEFENSE_RESPONSE | MSigDB lists | GO_DEFENSE_RESPONSE | 1056 | 236 | 15632 | 1249 |
Cx3cr1,H2-Q4,Ccl12,Ccr3,Ccl2,Il6,Nfkbiz,Tlr6,Mapkapk2,Ccl22,Trim13,Il4ra,Prdx1,Ifna1,Samhd1,Clec4n,Il10,Marco,C1rl,Lcn2,Plscr1,Ccrl2,Leng9,Tnfsf4,Itpkc,Irf1,Tlr2,Ifi213,Axl,Ifnar1,Ifi205,Acvr1,C1ra,H2-Q7,Pml,Icam1,Fgr,Sphk1,Nod1,Bmp2,Ifit1bl2,Gch1,Cd86,Caml,Nmi,Tlr1,Ifi208,Nfkbid,Tyk2,Kdm6b,Cd55,Clec5a,Ptgs2,Il12b,Clec4d,Il1rn,Eif2ak2,Plac8,Spn,Syk,Ass1,Ifnb1,Ddx60,Sdc1,Ifi214,Il15,Ifi207,S100a8,Ikbkg,Nfkb1,Mndal,Csf1,Trim21,Slpi,Ptk2,Lyn,Mmp25,Jak2,Ccl4,Tnf,H2-Q6,Bcl6,Gbp9,Sele,Gpr68,Dhx58,Rsad2,Nupr1,Cd74,Cd14,Tnfaip3,Fcgr4,Ccl5,Trim26,Il12rb1,Inhba,Cxcl2,Tlr3,Vcam1,Irak2,Nfkb2,Ifit1bl1,Nlrc5,Fos,Edn1,Irf4,Irgm2,Nod2,Egr1,Nlrp3,Ciita,Zbp1,Fcgr1,Adar,Tnfrsf14,Tap1,Psmb8,Ifit3,Itgal,Irf8,Casp4,Oas1a,Rasgrp1,Ifi203,Nox1,Ifi35,Stat1,Fam111a,Mefv,Pik3cd,Tnip1,Trem1,Cd300e,Xcr1,Src,Sp140,Apobec3,Cd40,Gbp4,Ly75,Irf2,Malt1,Ddx58,Hif1a,Cd180,Il1a,Stat2,Trim12c,Isg15,Cd83,Tnfrsf8,Notch1,Ifit1,Hck,Gbp2,Relb,Slc7a2,Ifna6,Adora2a,Oas2,H2-Ab1,Zc3h12a,Oas1g,Cxcl10,Ptafr,Elmod2,Thbs1,Pf4,Aoah,Gsdmd,Ppp1r14b,Nlrc4,Bnip3,Optn,Mid1,Ifna5,Fas,Fpr2,Cx3cl1,Il27,Slamf7,Clec4e,Zc3hav1,Olr1,Tnfrsf1b,Rel,Nos2,Ifi211,Isg20,Trim14,Trim56,Xaf1,Il18rap,Tlr9,C3,Oasl1,Tnip3,Ifi204,Ifit3b,Gbp2b,Ifit2,Oas3,Ankrd17,Csf3r,Tpst1,Ifi209,Stat3,Batf2,Tnfsf8,Mecp2,Prdx5,Aim2,F11r,Ifih1,Rnf135,Myd88,Batf,Ccl3,Ifna2,Ccr1,H2-Eb1,Gja1,Irf7,Serpine1,Icosl,Ddit4,H2-Aa,Hp,Ripk2,Hmox1,Adora2b,Il18,Cxcl1,Ikbke,Ptges,Il1b |
| 3.113e-51 | -116.30 | GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | MSigDB lists | GO_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 1257 | 261 | 15632 | 1249 |
Usp18,Cd74,Cd14,Tnfaip3,Tnf,Bcl6,Traf2,H2-Q6,Dhx58,Rsad2,Gpr68,Treml2,Tlr3,Irak2,Vcam1,Ccl5,Fcgr4,Pde4b,Lcp2,Wdfy1,Cxcl2,Inhba,Il12rb1,Nck1,Tmem176b,Ddx60,Irs2,Ifi214,Mul1,Il15,Ifi207,Syk,Spn,Eif2ak2,Stap1,Fcgr2b,Pde5a,Ifnb1,Phlpp1,Ap3b1,Ptk2,Lyn,Trib1,Ccl4,Jak2,Cdkn1a,Ikbkg,Nfkb1,Atm,Mndal,Casp8,Psme2,Csf1,Pml,Nfkbil1,H2-Q7,Psme1,Sell,Fgr,Icam1,Nod1,Ripk3,Ifnar1,Axl,Ifi213,Ifi205,Psmb9,Swap70,Dennd1b,C1ra,Traf3ip2,Cd55,Ptprj,Il12b,Clec4d,Plcl2,Hcar2,Ifit1bl2,Pik3r6,Cd86,Ifi208,Tlr1,Nmi,Tyk2,Nfkbid,Tlr6,Mapkapk2,Il4ra,Prnp,Ifna1,Samhd1,Ccl12,H2-Q4,Nfkbia,Jun,Cyfip1,Il6,Peli1,Myc,Abcb1a,Socs3,Itpkc,Cd200,Ebi3,Tnfsf4,Tlr2,Irf1,Acvr1b,Hcls1,Cd300lf,Rnf31,Clec4n,C1rl,Tnfsf14,Il10,Marco,Plscr1,Leng9,Smpdl3b,Pla2g7,Prdm1,Aim2,Psmb10,Ifih1,Rnf135,Tab2,Ccdc88b,Myd88,Ifna2,Irak3,Cd38,Csf3r,Ankrd17,Ifi209,Psmb6,Hmox1,Ripk2,Map3k8,Il18,Nr4a3,Adora2b,Kitl,Ikbke,Cxcl1,Il1b,H2-Eb1,Ccr1,Serpine1,Irf7,Fzd5,Tap2,Cd274,H2-Aa,Icosl,Bst1,Fas,Cx3cl1,Nr1h3,Ubash3b,Cd80,Clec4e,Slamf7,Cd34,Il27,Ahr,Zc3hav1,Ptpn2,Nlrc4,Mmp14,Parp9,Ifna5,C3,Tlr9,Egr3,Map2k4,Ifi204,Cacnb3,Tnip3,Nos2,Cav1,Ifi211,Zeb1,Tmem176a,Rictor,Lif,Itga4,Hlx,Malt1,Isg15,Socs1,Trim12c,Stat2,Ddx58,Hif1a,Cd180,Cd83,Relb,Myo10,Hck,Notch1,Hsph1,Src,Birc2,Cd40,Hspa1a,Tank,P2ry12,Pnp2,Casp3,Psma6,Zc3h12a,H2-Ab1,Ptger4,Serpinb9,Ptafr,Cxcl10,Tapbpl,Thbs1,Elmod2,Cmklr1,Pf4,Trafd1,Vegfc,Slc7a2,Samsn1,Ifna6,Csf3,Abr,Nlrp3,Fcgr1,Adar,Angpt1,Tap1,Tnfrsf14,Ezr,Ifit1bl1,Nlrc5,Psmd10,Fos,Prkce,Irf4,Cxcl14,Nod2,Stat1,Pik3cd,Tnip1,Actb,Clcf1,Siglece,Cd300e,Gfi1,Trem1,Birc3,Rabgef1,Psmb8,Itgal,Htra1,Ifi203,Rasgrp1,Jag1,Sirt1 |
| 4.011e-51 | -116.04 | GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN | MSigDB lists | GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN | 179 | 90 | 15632 | 1249 |
Psmb8,Ogfr,Ifit3,Plscr1,Oas1a,Stat1,Ifi35,Casp7,Irf1,Phf11d,Zcchc2,H2-Q4,Ifit1bl1,Stard5,Adar,Tap1,Phf11c,Samhd1,Gch1,Ifit1bl2,Cnp,Nmi,Ube2l6,Oas2,Uba7,Wars,Oas1g,Rnf19b,Herc6,Cxcl10,Acsl5,Trafd1,Il15ra,Casp1,N4bp1,Psmb9,Rab9,Slc15a3,Psma6,C1ra,Pml,Psme1,Malt1,Irf2,H2-Q7,Isg15,Ddx58,Stat2,Lap3,Psme2,Csf1,Trim14,Trim21,Isg20,Tdrd7,Xaf1,Oasl1,Ifit3b,Jak2,Spsb1,Eif2ak2,Gsdmd,Dnaja1,Usp25,Ddx60,Rtp4,Cx3cl1,Phf11a,Irf7,Plekha4,Tap2,Trim26,Parp12,Ripk2,Tlr3,Rcan1,Sp110,Phf11b,Ifit2,Rhbdf2,Oas3,H2-Q6,Arid5a,Ifi44,Dhx58,Rsad2,Ifih1,Psmb10,Usp18,Myd88 |
| 4.011e-51 | -116.04 | GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP | MSigDB lists | GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP | 179 | 90 | 15632 | 1249 |
Ifnar1,Cd40,Tapbp,Magohb,Psme1,Traf1,Isg15,Cd180,Ahsa1,Relb,Ifit1,Slc31a2,Cnp,Cd86,Oas2,Rnf19b,Herc6,Tapbpl,Serpinb9,Slfn9,Glrx,Hcar2,Cmpk2,Dio2,Igf2bp2,Lacc1,Samd9l,Egr1,Atf3,Pttg1,Zbp1,Pnpt1,Chmp4b,Psmb8,Ogfr,Zc3h12c,Ifit3,Ell2,Ppa1,Socs3,Ifi35,Mafg,Aida,Zcchc2,Ifit2,Batf2,Cers6,Rsad2,Cdyl2,Gbp3,Ifih1,Myd88,Sav1,Mvp,Hsd17b12,Pde4b,Irf7,Lcp2,Flrt2,Ppp1r15a,Pde7b,Parp12,Mmp13,Pcgf5,Cox18,Sp110,Spic,Stap1,Slfn8,Parp14,Ddx60,Rtp4,Sdc4,Enpp4,Isg20,Trim14,Trim21,Tdrd7,Oasl1,Mmp9,Mtdh,Ifit3b,Rab20,Mthfd2,Cd82,Adam19,Ccl4,Clcn7,Jak2,Ppfibp2 |
| 6.710e-51 | -115.53 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN | 156 | 84 | 15632 | 1249 |
Sp140,Ifit2,Phf11b,Tnf,Src,Oas3,Batf2,Ifi44,Dhx58,Rsad2,Errfi1,Tlk2,Csrnp1,Pml,Aim2,Gbp3,Trim12c,Isg15,Ifih1,Dtx3l,Slco3a1,Ddx58,Usp18,Stat2,Myd88,Ncoa7,Gch1,Slc31a2,Nampt,Ifit1bl2,Irf7,Cd274,Cnp,Ppm1k,Arl5b,Ddit4,Ube2l6,Oas2,Parp12,Hk2,Wars,Dusp5,Herc6,Cxcl10,Usp42,Ptgs2,Tnfsf10,Ikbke,Gtpbp2,Cmpk2,Sp110,Epsti1,Gadd45b,Ifit1bl1,Nlrc5,Znfx1,Stard5,Parp14,Ifnb1,Samd9l,Parp9,Ddx60,Rtp4,Zbp1,Cd80,Adar,Pnpt1,Phf11a,Il15,Tap1,Phf11c,Slfn5,Ifit3,Mov10,Plscr1,Trim21,Isg20,Xaf1,Trim56,Oasl1,Ifit3b,Phf11d,Irf1,Xcr1 |
| 6.916e-51 | -115.50 | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_UP | MSigDB lists | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_UP | 184 | 91 | 15632 | 1249 |
Mov10,Tnfrsf1b,Ikbkg,Tor3a,Zfp36,Psme2,Isg20,Trim21,Ifit3b,Dtx2,Dusp16,Jak2,Eif2ak2,Spsb1,Gadd45g,Vcan,Tor1aip2,Stxbp1,Il15,Irf7,Map2k1,Vps54,Slfn4,Tap2,Sap30,Trib3,Pcgf5,Ankrd17,Ifit2,Rsad2,Mafk,1110038F14Rik,Arg2,Gbp3,Psmb10,Ifih1,Usp18,Myd88,Traf5,Gnb4,Ogfr,Gbp7,Casp4,Ifit3,Psmb8,Irf1,Il13ra1,Stat1,Ifi35,Etnk1,Jun,Znfx1,Agrn,Il18bp,Prkce,Peli1,Il6,Irgm2,Tap1,Samhd1,Angpt1,Pnpt1,Adar,Lgals9,Nampt,Uba7,Nmi,Ube2l6,Cxcl10,Serpinb9,Grina,Traf3ip2,Fndc3a,Rnf19b,Trafd1,Tnfsf10,Clic4,Slfn3,Psmb9,N4bp1,Dusp1,Dync1h1,Tapbp,Pnp2,Socs1,Isg15,Pml,Psme1,Gbp2,Daxx,Ifit1 |
| 1.357e-50 | -114.82 | positive regulation of biological process | biological process | GO:0048518 | 6047 | 667 | 20694 | 1406 |
Gch1,Arid5a,Fcgr2b,Zfp281,Ift57,Irgm1,Met,Serp1,Myd88,Cacna1d,Kitl,Cx3cl1,Plekha2,Mdfic,Nlrc5,Kdr,Egr2,Cst7,Mark2,Txn1,Il1rn,Cgas,Kdm6b,Gadd45b,Spred3,Bcl6,Mmp25,Gdf15,Ppp1r15a,Pdlim7,Calcrl,Notch2,Egr1,Rgcc,Ube2e2,Cxcl14,Vcam1,Ddhd1,Rel,Sema4a,Ctsc,Plk2,Thbs1,Prdm9,Cacnb3,Cd34,Grk3,Prnp,Fbxo4,Vasp,Ciita,Cflar,Jag1,Il6,Kdm4a,Psme2,Ccnd2,Itga5,Hif1a,Mapkapk2,Fubp1,Ppp2r3a,Hmga2,Mdm2,Pdgfc,Psme1,Palld,Pcx,Crlf3,Relb,Tnfsf14,Ccnd1,Psmd10,Nr4a3,Hk2,Casp3,Gja1,Itgav,Ikbkg,Maml2,Dio2,Parp14,Ezr,Ddit4,Glrx,Scyl2,Slc9a1,Fcgr1,Apaf1,Tlr9,Pf4,Spic,Cxcl1,Glipr2,Ap3b1,Ell2,Hopx,Ccl7,Mecp2,Ppp2r1b,Vegfc,Dcun1d3,Cenpj,Rnf19b,Zeb1,Ccl9,Kmo,Myo10,Myc,Pde5a,Htr2a,Dcp1a,Plagl2,Fcgr4,Spry2,Dennd1b,Aff1,Dock4,Klf2,Ifih1,Triobp,Csrnp1,Birc2,Kcnj2,Lcn2,Tfec,Hcls1,Sec24a,Gpr68,Sema3c,Tnks1bp1,Egr3,H2-Ab1,Src,Stat3,Hck,Lpar1,Ikbke,Piezo1,Pdgfb,Klrk1,Mafg,Cxcl10,Ptafr,Ranbp2,Mndal,Optn,Abcc4,Pou2f2,Swap70,Trib1,Cycs,Tarm1,Il12rb1,Cd200,Mpp7,Maff,Adar,Cysltr2,H2-Q4,Ripk3,Crkl,Prdx5,Flrt3,Stat1,Nlrc4,Ccr1,Pml,Eya4,Ago3,Pim2,Pik3r5,Prdm1,Noct,Sod2,Fzd1,Ccl3,Ifi204,Stat4,Sh3bp4,Syk,Ccl4,Fabp3,Cd74,C3,Tlr1,Rnf31,Pde4b,Malt1,Gsdmd,Fpr1,Junb,Ifnb1,Nod1,Jdp2,Rabgef1,Serpinb9,Trim14,Ccl5,Map3k6,Ankrd17,Fgr,Psip1,Igf1r,Larp1,Msr1,Phip,Nox1,Wars,Adgrl2,Fam72a,Timeless,Cd38,Whamm,H2-M2,Hspa1b,Rab9,Tank,Fam129a,Bcl2a1d,Fos,Abr,Ahrr,Ankib1,Atm,Tent4a,Cd80,Higd1a,Acsl1,Trim13,Hp,Txnrd1,Gpsm2,Acsl5,Axl,Irf8,Pik3r6,Dhx58,Hhex,H2-T24,Fam20c,Arf4,Ier3,Lyn,Sell,Ncoa7,Il4ra,Tnip1,Ifi209,Ahr,Sdc1,C1rl,Clcf1,Helz2,Rims3,Ptch1,Lmo4,Htr2b,S100a8,Acvr1,Plaur,Hinfp,Nr4a1,Tnfsf4,Hdac1,Adam19,Cdc42ep4,Plau,Ehd1,Aim2,Adora2a,Abcb1a,Mcoln2,Ptger4,Mov10,Atp2b4,Ets2,Mmp13,Cop1,Itgb8,Hivep3,Enpp4,Nectin2,Irak3,Gadd45g,Zfp36,Carmil1,Serpine1,Nfkbid,Flrt2,Pla2g7,Nod2,Lrp8,Tap2,H2-Q7,D16Ertd472e,Sp110,Stap1,Trim21,Homer1,Nmi,Ptprj,Ass1,Tnfsf8,Map4k4,Asns,Icosl,Cdc42ep2,Dyrk2,Csf3,Gcnt2,Parp9,Ifi208,Cyth3,Sesn3,Ifna4,Irgm2,Nos2,Tab2,Wdr59,Smc5,Scn1b,Cxcl9,Spred1,Htra1,Pid1,Notch1,Tiparp,Cd300lf,Irak2,Itgal,Themis2,Clec4e,Pim1,Tlr2,Clec4d,Hmox1,Uaca,Cdkn1a,Casp8,Nampt,Etv5,Pla2g4a,Sdc4,Abcc1,Nck1,Ifna6,Rnf19a,Gpr35,Acvrl1,Tnfsf10,P2ry12,P2ry2,H2-Aa,Cacybp,Dusp6,Sik3,Ccdc88b,Cd55,Traf3ip2,Agrn,Il12b,Mefv,Bnip3,Ifi214,Ednrb,Tra2a,Cd14,Sinhcaf,Tnip3,Tmem67,Casp2,Bmp2,Lhx2,Tnfsf9,Plek,Il2rg,Mid1,Tnfrsf8,Cnn2,Nfkb2,G3bp2,Dusp1,Acvr1b,Trib3,Pmaip1,Tet2,Polr2g,Il1b,Isg15,Mlkl,Btg2,Hsd17b12,Ifna1,Tnfrsf14,Ppp2r5a,Nfkb1,4930453N24Rik,Cdk5r1,Prkce,Plat,Ifi205,Nfkbiz,Tlr3,H2-T10,Ifnar1,Birc3,Mllt6,H2-Q6,Med21,Evl,Arrdc4,Nfkbia,Adrb2,Ccl2,Batf,Map3k8,Ppm1k,Stat5a,Socs1,Pdpn,Plagl1,Eif2ak2,Pnpt1,Eef1e1,Rbpms,Plekhn1,Tnc,Socs3,Ifna2,Arid4a,Ptk2,Gda,Fosb,Kdm5b,Rac3,Etv6,Prag1,Nr1h3,Ccl8,Fzd5,Ptpn2,Cebpd,Pdgfrb,Col18a1,Gsap,Dnajb2,Nupr1,Csf1,Hcar2,Il15,Hspa2,Antxr1,Spen,Ifrd1,S1pr2,Rhoq,Fpr2,Odc1,Stat2,Trim12c,Eif4g2,Map2k1,Treml4,Cox17,Nr3c1,Peli1,Phlda1,Bcl2l11,Tnfsf15,Wdr43,Gpc1,Psma6,Lif,Raet1e,Usp12,Flt1,Arg2,Rgs14,Akt3,Zc3hav1,Scimp,Nlrp3,Clec4n,Ifi211,Plac8,Tnfrsf1b,Rnf139,Irf7,Tnfaip3,Inhba,Pgk1,Rictor,Ddx58,Hmgn3,Traf5,Zbp1,Sphk1,Tcea1,Lcp2,Jak2,Tlr6,Timp1,Atf3,Rras2,Ccl12,Rasgrp1,Sertad3,Taf4b,Acpp,Il27,Ikzf1,Angpt1,Jun,Tcf4,Pcgf5,Fam162a,Rsad2,Nsmaf,Mapkbp1,Tnf,Plk3,Il1a,Daxx,Tpx2,Rnf135,Cited2,Bambi,Stxbp1,Parp3,Cd180,Pou3f1,Gclc,Fscn1,Lipg,Max,Arid5b,Nqo1,Kat2b,Jmjd6,Irs2,Hk1,Icam1,Nlgn2,Mycl,Mtdh,Cd40,Dr1,Dync1h1,Adora2b,F10,Cd86,Rap2c,Rapgef2,Hsph1,Pik3cd,Spn,Plscr1,Mmd,Bcl9,Syne2,Traf1,Ier2,Ksr1,Ifit2,Ptgs2,Cyfip1,Nfil3,Klf6,Casz1,Hilpda,Il15ra,Lgals9,Cd274,Cd83,Arel1,Ccl22,Mmp9,Sirt1,Cav1,Klf7,Osm,Myadm,Pbx1,Trim30a,Spire1,Dbnl,Sqstm1,Acod1,Itpr1,Cx3cr1,H60b,Rab21,Il10,Intu,Irf2,Ppp1r15b,Map2k4,Phlpp1,Irf1,Tspo,Fchsd2,Plpp3,Hspa1a,Cmklr1,Cenpe,Lnpk,Bst1,Kif3c,C1ra,Ddx60,Phldb1,Mmp14,Rhoc,Sav1,Med13,Ccr3,Itga4,Dtx3l,Irf4,Mtcp1,Hmga1,Pkp4,Nsd3,Fas,Stau1,Dnaja1,Edn1,Sema4c,Resf1,Ifi203,Pvr,Hap1,Ccne1,Jarid2,Casp1,Ldlr,Il18rap,Casp4,Trim26,Clec5a,Hivep2,Mul1,Hlx,Ripk2,Tifa,Lrp4,Rnf14,Wdfy1,Tmod3,Nek6,Traf2,Ifna5,Trip10,Gfi1,Sele,Chmp4b,Scarf1,Tomm70a,Ythdf1,Zc3h12a,Il18,H2-T22,Gpr18,Frmd4a,Marcksl1,Marco |
| 1.368e-50 | -114.82 | GSE36009_WT_VS_NLRP10_KO_DC_UP | MSigDB lists | GSE36009_WT_VS_NLRP10_KO_DC_UP | 181 | 90 | 15632 | 1249 |
Arf4,Plekhn1,Ap3m2,Nfil3,Max,Casp7,Uaca,Parp11,Csf1,Isg20,Trim56,Tdrd7,Etv6,Ogfr,Gbp7,Zbtb5,Slamf7,Zbp1,Adar,Enpp4,Chmp4b,Rbl1,Slfn5,Ddx60,Atf3,Usp25,Nkiras1,Coa5,Prnp,Kat2b,Il4ra,Slc30a1,Pla2g4a,Spry2,Tor1aip2,Il6,Il18bp,Rin2,Morc3,Nlrc5,Gsdmd,Fos,Tiparp,Nfxl1,Slfn3,Inpp1,Prkx,Gcnt2,Keap1,Smox,Fam53c,Larp1,Parp3,Fndc3a,Usp42,Tapbpl,Nsmaf,Il18,Nmi,Parp12,Arid4a,Nampt,4930523C07Rik,Rgl1,Card6,Sesn3,Slfn4,Ascc3,Osm,Crlf3,Crim1,Mcmbp,Ube2e1,Lrch3,Zfp513,Cd180,Trim12c,Gbp3,Pigv,Minpp1,Tnfsf8,Rab9,Treml2,Fgl2,Cers6,Parp8,Plod3,Casp1,Oas3,Tcf4 |
| 1.439e-50 | -114.77 | GSE6259_DEC205_POS_DC_VS_BCELL_DN | MSigDB lists | GSE6259_DEC205_POS_DC_VS_BCELL_DN | 161 | 85 | 15632 | 1249 |
Rnf19b,Serpinb9,Slamf8,Tgfbi,Keap1,Il15ra,Csrp1,Ifit1bl2,Ccnj,Irf7,Ppm1k,Nmi,Oas2,Pde7b,Rapgef2,Lif,Pml,Psme1,Gbp3,Psmb10,Isg15,Icam1,Atp11a,Nod1,Gbp2,Daxx,N4bp1,Ifit2,Phf11b,Tpst1,Psmb9,Setdb2,Ifi44,Ly75,Slc15a3,Ppa1,Tlr9,Etnk1,Slc25a22,Asb13,Azi2,Cacnb3,Phf11d,Aida,Kdr,Tnip1,Zcchc2,Fscn1,Polr2g,Arf4,Psmb8,Mov10,Psme2,Trim21,Ociad1,Tdrd7,Eef1e1,Xaf1,Slamf9,Lrp8,Ddx60,Xrn1,Nr1h3,Nmral1,Tspo,Zbp1,Pnpt1,Phf11a,Il15,Dnase1l3,Phf11c,Chmp4b,Rnf114,Gadd45b,Aoah,Nfkbia,Eif2ak2,Ifit1bl1,Gsdmd,Plac8,Znfx1,Msr1,Bbx,Tmem171,Parp14 |
| 2.505e-50 | -114.21 | GSE22589_HEALTHY_VS_HIV_INFECTED_DC_DN | MSigDB lists | GSE22589_HEALTHY_VS_HIV_INFECTED_DC_DN | 182 | 90 | 15632 | 1249 |
Psme2,Tdrd7,Tor3a,Gem,Plod2,Vezt,Mov10,Clec4e,Slfn5,Atp11b,Stxbp1,Ddx60,Aldh1b1,Rtp4,Dcp2,Parp14,Optn,Rnf114,Slc29a3,Acp2,Epsti1,Fam53c,Naa25,Tlr3,Frmd4a,Cox18,Sap30,Wdfy1,Tbc1d13,Snx2,Irf7,Lcp2,1600014C10Rik,Stau1,Ch25h,Gbp3,Fabp3,Psmb10,Gbp9,Ddhd1,Tnf,Endod1,Casp7,Slc25a22,Irf1,Akt3,Ccrl2,Oas1a,Rnf31,Gbp7,Rbm43,Pnpt1,Rbms2,Tap1,Slc28a2,Angpt1,Mapkapk2,Pttg1,Trim13,Ppp2r5a,Plcl2,Elmod2,Trafd1,Dcbld2,Oas1g,Herc6,Ptafr,Slamf8,Tlr1,Uba7,Card6,Junb,Slc7a2,Plk2,Ppm1k,Gbp2,Pml,Socs1,Cd180,Rab19,Stat2,Dbnl,Setdb2,Gbp4,Tapbp,Ccnd1,Gypc,Gpsm2,Acpp,Psmb9 |
| 2.802e-50 | -114.10 | GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | 162 | 85 | 15632 | 1249 |
Socs3,Dram1,Rcsd1,Ier3,Acsl1,Tnip3,Rap2c,Ccl4,Tnfaip2,Clcf1,Cflar,Dcun1d3,Ppp1r15b,Birc3,Il10,Zc3h12c,Pdss1,Tifa,Zfp36,Ccrl2,Nfkbiz,Nlrp3,Clec4e,Pim3,Sdc4,Pfkfb3,Zc3hav1,Sod2,Bcl2a1b,Nfkbia,Flt1,Rhof,Ets2,Peli1,Il6,Dusp2,Kcnj2,Ifnb1,Ripk2,Zc3h12a,Rnf19b,Il18,Map3k8,Ptgs2,Clic4,Irak2,Serpinb2,Cxcl1,Bcl2a1a,Il1b,Plaur,Gch1,Snx10,Plek,Osm,Ppm1k,Ppp1r15a,Cd274,Slc2a6,Arl5b,Gpr132,Cxcl2,Adora2a,Rapgef2,Csf3,Rhoh,Csrnp1,Plk3,Traf1,Kmo,Il1a,Icam1,Sav1,Cd83,Tnfaip3,Plekhf2,Ehd1,Tnf,Klf6,Stat5a,Rbbp8,Tank,Itgb8,Gpr84,Bcl2a1d |
| 4.103e-50 | -113.72 | GO_RESPONSE_TO_BIOTIC_STIMULUS | MSigDB lists | GO_RESPONSE_TO_BIOTIC_STIMULUS | 762 | 192 | 15632 | 1249 |
Tlr1,Ifi208,Gch1,Junb,Ifit1bl2,Cd86,Cmpk2,Clec4d,Il12b,Ptgs2,Casp1,Ifnar1,Ifi213,Axl,Ifi205,Eno1,Psmb9,Nod1,Pml,H2-Q7,Nfkbil1,Fgr,Icam1,Plscr1,Leng9,Clec4n,P2ry2,Il10,Itpkc,Socs3,Tnfsf4,Tlr2,Irf1,Il6,Peli1,Il18bp,Ccl12,Nfkbia,Cx3cr1,H2-Q4,Jun,Plau,Ifna1,Samhd1,Tlr6,Mapkapk2,Il4ra,Ccl22,Cxcl2,Ccl5,Fcgr4,Pde4b,Irak2,Nfkb2,Vcam1,Tlr3,Ifi44,Gbp9,Dhx58,Rsad2,Sele,Tnf,H2-Q6,Cd14,Tnfaip3,Slpi,Nfkbib,Ppp1r15b,Ikbkg,Nfkb1,S100a8,Casp8,Mndal,Ccl4,Jak2,Lyn,Trib1,Stap1,Ifnb1,Syk,Ass1,Eif2ak2,Plac8,Spn,Ifi207,Ddx60,Nck1,Ifi214,Ifna6,Oas2,Csf3,Cnp,Elmod2,Pf4,Gng12,Zc3h12a,Oas1g,Ptger4,Cxcl10,Ptafr,Serpinb9,Gbp4,Casp3,Apobec3,Src,Cd40,Tnfrsf8,Hck,Notch1,Ifit1,Malt1,Socs1,Trim12c,Isg15,Cd180,Ddx58,Hif1a,Stat2,Ifi203,Oas1a,Ifit3,Irf8,Gfi1,Trem1,Stat1,Fam111a,Prkce,Irf4,Edn1,Nod2,Bcl2l11,Ifit1bl1,Nlrc5,Fos,Adar,Tnfrsf14,Abr,Nlrp3,Ddit4,H2-Eb1,Irf7,Serpine1,Fzd5,Ikbke,Cxcl1,Il1b,Ptges,Ripk2,Hp,Il18,Tnfsf8,Batf2,Ifit2,Oas3,Ankrd17,Ifi209,Batf,Myd88,Irak3,Ifna2,Apaf1,Ifih1,Ifi211,Isg20,Trim56,Ednrb,Tnfrsf1b,Nos2,Cav1,Gbp2b,Pim2,Oasl1,Ptgir,Mtdh,Tlr9,Ifit3b,Odc1,Tnip3,Ifi204,Pla2g4a,Bnip3,Ifna5,Optn,Hmga1,Nlrc4,Tspo,Cd80,Clec4e,Il27,Zc3hav1,Fas,Nr1h3 |
| 5.508e-50 | -113.42 | GSE2706_UNSTIM_VS_2H_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_R848_DC_DN | 167 | 86 | 15632 | 1249 |
Marcksl1,Icam1,Il1a,Traf1,Isg15,Myo10,Ehd1,Stk40,Psma6,Ptger4,Kdm6b,Herc6,Zc3h12a,Dusp5,Grina,Ptgs2,Il12b,Cxcl10,Serpinb9,Il15ra,Plaur,Cmpk2,Gch1,Btg2,Tnfsf15,Slc7a5,Nfkbid,Maff,Stx11,Nfkbiz,Sgms2,Slc25a25,Tap1,Nfkbia,Pik3r5,Edn1,Kcnj2,Il6,Socs3,Acsl1,Cflar,Clcf1,Tnfaip2,Rgs1,Birc3,Irf8,Zc3h12c,Ifit3,Stat4,Ccrl2,Plk3,Mcoln2,Csrnp1,Rab3ip,Plagl2,Tnfaip3,Ifit2,Rsad2,Nr4a3,Map3k8,Cxcl1,Irak2,Il1b,Plek,Ccl5,Ppp1r15a,Gpr132,Arl5b,Rapgef2,Inhba,AA467197,Cxcl2,Sdc4,Pim3,Slamf7,Gadd45b,Dram1,Ifit3b,Ccl4,Dcun1d3,Nfkb1,Rel,Gem,Isg20,Nfkbib,Usp12 |
| 6.399e-50 | -113.27 | negative regulation of biological process | biological process | GO:0048519 | 5252 | 603 | 20694 | 1406 |
Ifi208,Parp9,Sesn3,Nos2,Gbp4,Spred1,Slfn3,Htra1,Xcr1,Nmi,Tlk2,Ptprj,Tapbpl,Nfkbie,Ass1,Aoah,Map4k4,Asns,Dyrk2,Gcnt2,Csf3,Gng4,Pim1,Tlr2,Hmox1,Uaca,Klf8,Pid1,Rgs1,Rhoh,Notch1,Tiparp,Cd300lf,Irak2,Shfl,Aim2,Adora2a,Abcb1a,Mov10,Ptger4,Atp2b4,Ets2,Hinfp,Plaur,Acvr1,Nr4a1,Tnfsf4,Hdac1,Plau,Carmil1,Tmsb10,Serpine1,Tmem176b,Nfkbid,Radx,Nod2,Tap2,Tent2,Stap1,Trim21,Tsku,Xrn1,Morc3,Itgb8,Irak3,Gadd45g,Ctla2a,Zfp36,Bcl2a1d,Abr,Olr1,Ahrr,Atm,Tent4a,Cd80,Nes,Higd1a,Stoml1,Isg20,Rgs3,Dusp2,Fam72a,Cd38,Timeless,Whamm,Hspa1b,Cdyl,Tank,Fam129a,Lyn,Chst11,Kremen1,Il4ra,Slc7a11,Ncoa7,Tnip1,Ahr,Ifi209,Clcf1,Helz2,Ptch1,Htr2b,Lmo4,Trim13,Hp,Grina,Irf8,Axl,Dhx58,Hhex,Tap1,Arf4,Klf3,Ier3,Sod2,Fzd1,Oasl1,Ifi204,Ric1,Sh3bp4,Pde3b,Ccl4,Ccr1,Ciapin1,Pml,Eya4,Ago3,Pim2,Bfar,Milr1,Prdm1,Noct,Col4a2,Cdkn2d,Ifnb1,Jdp2,Rabgef1,Serpinb9,Trim14,Ccl5,Ankrd17,Igf1r,Larp1,Msr1,Phip,Wars,Cd74,C3,Rnf31,Pde4b,Actb,Junb,Lpar1,Lrch1,Serpina3f,Fam111a,Ero1l,Pdgfb,Xaf1,Cxcl10,Hcls1,Gpr68,Sema3c,Smpdl3b,H2-Ab1,Egr3,Src,Stat3,Hck,Trib1,Ncoa5,Tarm1,Cd200,Adar,Hat1,Crkl,Prdx5,Bcor,Stat1,Spint2,Mndal,Optn,Swap70,Hk3,Hopx,Mecp2,Phactr4,Tulp3,Vegfc,Dcun1d3,Znrf3,Cenpj,Ezr,Parp14,Ddit4,Glrx,Scyl2,Slc9a1,Pf4,Tlr9,Spry2,Dock4,Klf2,Birc2,Dusp16,Dync1i2,Oas1b,Zeb1,Ccl9,Clec2d,Myc,Pde5a,Htr2a,Dcp1a,Ciita,Sap30,Cflar,Dusp8,Jag1,Il6,Kdm4a,Ccnd2,Hif1a,Itga5,Rel,Sema4a,Samhd1,Ctsc,Gem,Plk2,Mt1,Thbs1,Cacnb3,Grk3,Cd34,N4bp1,Prnp,Fbxo4,Pcx,Crlf3,Zmynd15,Relb,Tnfsf14,Ccnd1,Psmd10,Nr4a3,Hk2,Casp3,Gja1,Itgav,Ikbkg,Pttg1,Mapkapk2,Hmga2,Ppp2r3a,Mdm2,Gpr132,Procr,Kitl,Magohb,Cx3cl1,Mdfic,Nlrc5,Ubash3b,Kdr,Plaat3,Gfpt1,Siglece,Arid5a,Fcgr2b,H3f3b,Zfp281,Dcbld2,Ift57,Mafk,Met,Myd88,Notch2,Zhx2,Calcrl,Pmepa1,Egr1,Rgcc,Kmt5a,Cxcl14,Dnajb4,Eno1,Cst7,Rcan1,Cgas,Il1rn,Txn1,Rnd1,Gadd45b,Spred3,Bcl6,Dusp4,Gdf15,Fabp7,Ppp1r15a,Mul1,Hlx,Lrp4,Stk40,Znfx1,Rhbdf2,Tmod3,Mvp,Serpinb6b,Usp25,Tmem178,Traf2,Ifi203,Hap1,Ccne1,Jarid2,Smg7,Ldlr,Tut7,Trim26,Nfkbil1,Clec5a,Osgin2,Gpr18,Frmd4a,Nfkbib,Crbn,Foxp4,Prokr1,Trip10,Gfi1,Chmp4b,Slfn2,Serpinb9b,Tomm70a,Zc3h12a,Il18,Fgl2,Rab11fip1,Tspo,Serpina3g,Plpp3,Cenpe,Hspa1a,Cmklr1,Dach1,Cx3cr1,Il10,Intu,Ppp1r15b,Map2k4,Phlpp1,Irf1,Nsd3,Fas,Socs7,Dnaja1,Trip13,Prkar2b,Edn1,Serpinb2,Sema4c,Cish,Resf1,Mmp14,Sgk3,Sav1,Med13,Ptgir,Gclm,Dtx3l,Svbp,Lnpep,Irf4,Oasl2,Ptgs2,Ifi213,Nfil3,Cyfip1,Ddx4,Slpi,Casz1,Adora2b,Marf1,Cd86,Rap2c,Hsph1,Rapgef2,Pik3cd,Tax1bp1,Mier3,Spn,Plscr1,Dusp5,Cav1,Klf7,Osm,Myadm,Pbx1,Trim30a,Dbnl,Sqstm1,F11r,Acod1,Itpr1,Riox2,Il15ra,Lgals9,Cd274,Cd83,Arel1,Plcl2,Etv3,Sirt1,Mmp9,Jun,Tcf4,Rsad2,Mapkbp1,Plk3,Tnf,Il1a,Daxx,Cited2,Bambi,Stxbp1,Atf3,Ccl12,Caml,Parp10,Sertad3,Asah2,Mxd1,Pilrb1,Ikzf1,Angpt1,Uchl1,Kat2b,Irs2,Hk1,Icam1,Mtdh,Pfkl,Rbl1,Dr1,Parp3,Gclc,Max,Rpgrip1l,Insl6,Aida,Arid5b,Nqo1,Gpc1,Lif,Flt1,Oas1a,Arg2,Fpr2,Eif4g2,Map2k1,Nr3c1,Peli1,Bcl2a1a,Tnfaip3,Pgk1,Inhba,Ptges,Vasn,Sphk1,Rap1gap2,Cdyl2,Tlr6,Jak2,Timp1,Errfi1,Akt3,Rgs14,Zc3hav1,Nlrp3,Ifi211,Plac8,Tnfrsf1b,Rnf139,Aebp2,Stat5a,Socs1,Pdpn,Slfn1,Eif2ak2,Pnpt1,Eef1e1,Plekhn1,Rnf34,Apobec3,Socs3,Tnc,Arid4a,Birc3,Mllt6,D1Ertd622e,Trafd1,Sco1,Slamf8,Evl,Adrb2,Slc30a1,Nfkbia,Dcp2,Gtpbp2,Ppp1r14b,Ccl2,Oas3,Zc3h7a,Dnajb2,Csf1,Nupr1,Hcar2,Il15,Spen,Antxr1,Hspa2,Ifrd1,S1pr2,Rhoq,Rab3ip,Ptk2,Kdm5b,Etv6,Prag1,Tle3,Nr1h3,Ptpn2,Fzd5,Cebpd,Pdgfrb,Cnn2,Mid1,Dusp1,Acvr1b,Zbtb5,Casp2,Bmp2,Cpeb4,Lhx2,Nmral1,Plek,Tnfrsf14,Ppp2r5a,Oas1g,Nfkb1,Prkce,Cdk5r1,Keap1,Plat,Ifi205,Trib3,Pmaip1,Polr2g,Il1b,Isg15,Pim3,Ttc39b,Rfx5,Btg2,Acp5,P2ry12,Rffl,P2ry2,Lztfl1,H2-Aa,Cacybp,Dusp6,Bcl2a1b,Cdkn1a,Phf6,Ifi207,Nampt,Casp8,Rbbp8,Trim56,Katna1,Sdc4,Abcc1,Nck1,Tmem176a,Acvrl1,Gpr35,Srgn,Sinhcaf,Tnip3,Clic4,Mosmo,Stxbp3,Tmem67,Agrn,Il12b,Mefv,Bnip3,Ifitm1,Ifi214,Samsn1,Ednrb |
| 1.042e-49 | -112.79 | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | 164 | 85 | 15632 | 1249 |
Ccl4,Tnfaip2,Cflar,Socs3,Pim2,Dram1,Acsl1,Ier3,Adrb2,Tnip3,Dnajb4,Pdss1,Tifa,Usp12,Stat4,Ccrl2,Nfkb1,Ppp1r15b,Dcun1d3,Birc3,Gem,Rel,Il10,Slamf7,Pim3,Sdc4,Egr1,Nfkbiz,Nlrp3,Peli1,Dusp2,Edn1,Sod2,Bcl2a1b,Gramd1a,Gadd45b,Hivep2,Nfkbia,Jun,Ets2,Cxcl1,Bcl2a1a,Il1b,Plaur,Il15ra,Ripk2,Zc3h12a,Dusp5,Kdm6b,Map3k8,Il18,Il12b,Nsmaf,Ptgs2,Slc7a5,Arl5b,Ddit4,Maff,Cxcl2,Inhba,Rapgef2,Nfkbid,Gch1,Plek,Txn1,Osm,Ppp1r15a,Cd274,Sav1,Cd83,Tnfaip3,Rhoh,Csrnp1,Plk3,Rnd1,Icam1,Il1a,Gpr84,Bcl2a1d,Errfi1,Plekhf2,Tnf,Stat5a,Dusp1,Otud1 |
| 2.675e-49 | -111.84 | GSE44649_WT_VS_MIR155_KO_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE44649_WT_VS_MIR155_KO_ACTIVATED_CD8_TCELL_UP | 186 | 90 | 15632 | 1249 |
Ifit3,Ogfr,Casp4,Gbp7,Cflar,Rgs1,Ifi35,Ebi3,Itpkc,Ppa1,Irf1,Gpd2,Irf4,Irgm2,Il4i1,Bbx,Triobp,Nlrc5,Agrn,Bcl2l11,Sbds,Znfx1,Tspan3,Tap1,Tmtc2,Etv3,Stoml1,Samsn1,Lad1,Il1rn,Clic4,Slfn9,Trafd1,Ptger4,Herc6,Serpinb9,Tapbp,Ehd1,Gypc,N4bp1,Swap70,Cd40,Cd83,Relb,Psme1,Mthfr,Stat2,Socs1,Ociad1,Mmd,Jdp2,Rel,Ldlr,Nfil3,Cacnb3,Ifit3b,Slfn8,Parp14,Dusp2,Ifrd1,Phlpp1,Mllt6,Parp9,Spsb1,Gsdmd,Rnf114,Ptpn2,Trip10,Il15,Tspo,Foxp4,Slfn5,Ddx60,Fas,Cdk5r1,Nxf1,Ccl5,Fzd5,Tap2,Snn,St7,Rsad2,Dhx58,Tpst1,Apaf1,Prdm1,Csrnp1,F11r,Rnd1,Psmb10 |
| 2.977e-49 | -111.74 | GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_DN | MSigDB lists | GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_DN | 199 | 93 | 15632 | 1249 |
Lap3,Mndal,Casp8,Xaf1,Tdrd7,Psme2,Trim14,Trim21,Isg20,Ifi211,Ifit3b,Ifi204,Oasl1,Ets2,Rnf114,Eif2ak2,Optn,Ifi214,Fas,Ddx60,Tle3,Zc3hav1,Ifi207,Phf11a,Il15,Irf7,Tap2,Parp12,Trim26,Ext1,Cdc42ep4,Tlr3,Sp110,Gtpbp2,Ifi209,Oas3,H2-Q6,Phf11b,Ifit2,Rsad2,Tlk2,Ifi44,Stat3,Psmb10,Ifih1,Usp18,Myd88,Ogfr,Ifit3,Rnf31,Psmb8,Dcp1a,Ifi203,Oas1a,Plscr1,Irf1,Phf11d,Stat1,Casp7,Ifi35,Zcchc2,H2-Q4,Ifit1bl1,Samhd1,Tap1,Phf11c,Adar,Ifit1bl2,Maff,Oas2,Ifi208,Nmi,Ube2l6,Serpinb9,Oas1g,Herc6,Rnf19b,Trafd1,Il15ra,Tnfsf10,Ifi205,Psmb9,Ifi213,Tapbp,Slc15a3,Isg15,Trim12c,Socs1,Stat2,Ddx58,Pml,Psme1,H2-Q7 |
| 4.776e-49 | -111.26 | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | 187 | 90 | 15632 | 1249 |
Rcan1,Ripk2,Stip1,Snn,Vcam1,Vps54,Pde4b,Car13,Spint2,Rnd1,Ch25h,Csrnp1,Plagl2,Cd14,Arid5a,Stat5a,Klf6,Aebp2,Arhgap26,Oaf,Cacnb3,Sema4c,Mtdh,Dusp16,Nfil3,Rap2c,Rel,Hdc,Ppp1r15b,Dcun1d3,Jdp2,Stx6,Rhou,Zfp36,Nfkbib,Cx3cl1,Nck1,Aff1,Spred1,Ptpn2,Trim36,Itgav,Optn,Psd,Lrch1,Mob3b,Pim1,Il12b,Zc3h12a,Plaur,Hcar2,Tfec,Prkx,Clic4,Jarid2,Slc4a7,Stx11,Wdr59,Slc2a6,Spata13,Sphk1,Nfkbil1,Ier2,Slc30a4,Mapkbp1,Cd83,Src,Spryd7,Lztfl1,Fchsd2,Rffl,Kpna3,Filip1l,Stard7,Dr1,P2ry2,Slc39a14,Ccrl2,Hivep3,Etv3,Pgs1,Ppfibp1,Rras2,Pfkfb3,Tet2,Ezr,Flt1,Kremen1,Edn1,Il4i1 |
| 8.482e-49 | -110.69 | GSE17301_CTRL_VS_48H_ACD3_ACD28_STIM_CD8_TCELL_DN | MSigDB lists | GSE17301_CTRL_VS_48H_ACD3_ACD28_STIM_CD8_TCELL_DN | 188 | 90 | 15632 | 1249 |
Sod2,Rapgef5,Aoah,Mrpl52,Gpr18,Mmp14,Cpd,Ift57,Mllt6,Col18a1,Fpr2,Sdc1,Pilra,Pilrb2,Fbrsl1,Nfkb1,Pid1,Cav1,Alas1,Tmem176a,Pou2f2,Slamf9,Pim2,C3,Rab20,Lyn,Tnf,Zmynd15,Cd302,Nfkbie,Hdac1,Nupr1,Cd74,Ube2f,Myd88,Tnfaip3,Irak3,Ccl5,Pde4b,Lcp2,Vasp,Cxcl2,Car13,Il2rg,Map3k8,Ralgds,Ikbke,Pilrb1,Acp2,Pik3r5,Nfkbia,Psmd10,Igsf6,Nfkbiz,Pfkfb3,Casp4,Marco,Zc3h12c,Gna15,Pla2g7,Smpdl3b,Ebi3,Mtmr14,Tlr2,Tnfaip2,Tnip1,Ifnar1,N4bp1,Clmp,Ehd1,Hspa1a,Tank,Swap70,Gpr84,Marcksl1,Slco3a1,Icam1,Myo10,Hck,Relb,Slc31a2,Junb,Stx11,Zc3h12a,Ptger4,Rnf19b,Ptprj,Fpr1,Ak4,Glrx |
| 8.849e-49 | -110.65 | regulation of protein metabolic process | biological process | GO:0051246 | 2759 | 387 | 20694 | 1406 |
Ccl3,Fzd1,Ccl4,Syk,Ric1,Ccnj,Ago3,Ccr1,Pml,Pik3r5,Rabgef1,Serpinb9,Ccl5,Ifnb1,Nod1,Cdkn2d,Jdp2,Wars,Nox1,Phip,Larp1,Igf1r,Map3k6,Fgr,Vrk2,Tlr1,Cd74,C3,Malt1,Actb,Ahrr,Ankib1,Bcl2a1d,Acsl1,Higd1a,Cd80,Atm,Dusp2,Hspa1b,Fam129a,Tank,Cdyl,Fam72a,Clcf1,Ncoa7,Tnip1,Lyn,Htr2b,Hhex,Pik3r6,Ier3,Adora2a,Aim2,Mov10,Ptger4,Atp2b4,Acvr1,Plaur,Nr4a1,S100a8,Hdac1,Lrp8,Nod2,Serpine1,Xrn1,Stap1,Trim21,Cop1,Zfp36,Ctla2a,Gadd45g,Irak3,Tab2,Nos2,Gbp4,Ifna4,Irgm2,Parp9,Spred1,Nmi,Tlk2,Ptprj,Icosl,Gcnt2,Csf3,Map4k4,Tlr2,Pim1,Uaca,Notch1,Pid1,Tiparp,Irak2,Mdfic,Cx3cl1,Kitl,Kdr,Ubash3b,Fcgr2b,Arid5a,Met,Myd88,Serp1,Ift57,Rgcc,Pmepa1,Egr1,Notch2,Spred3,Gadd45b,Txn1,Il1rn,Rcan1,Cst7,Ppp1r15a,Mmp25,Dusp4,Gdf15,Bcl6,Dusp8,Cflar,Ppp6r1,Itga5,Psme2,Ccnd2,Kdm4a,Il6,Ctsc,Rel,Fbxo4,Prnp,Grk3,N4bp1,Plk2,Thbs1,Psmd10,Tnfsf14,Ccnd1,Ikbkg,Casp3,Itgav,Gja1,Ppp2r3a,Mapkapk2,Psme1,Pdgfc,Mdm2,Ccl7,Glipr2,Phactr4,Vegfc,Dcun1d3,Ppp2r1b,Mecp2,Ddit4,Parp14,Ezr,Tlr9,Apaf1,Fcgr1,Spry2,Birc2,Dusp16,Klf2,Ccl9,Ppp4r2,Rnf19b,Htr2a,Myc,Pde5a,Serpina3f,Lpar1,Ptafr,Pdgfb,Hcls1,Sec24a,Src,Stat3,Tnks1bp1,Cysltr2,Ripk3,Adar,Trib1,Cycs,Spint2,Nlrc4,Prdx5,Stat1,Bcor,Crkl,Swap70,Daxx,Il1a,Mapkbp1,Tnf,Plk3,Jun,Fam162a,Tpx2,Parp10,Caml,Ccl12,Rasgrp1,Atf3,Angpt1,Prdx1,Il27,Icam1,Kat2b,Uchl1,Igf2bp2,Cd40,Gclc,Aida,Lipg,Ptgs2,Ksr1,Mmd,Slpi,Cyfip1,Ppp2r2a,Rap2c,Dusp5,Spn,Hsph1,Rapgef2,Myadm,Trim30a,Osm,Cav1,Samd9l,Sqstm1,Lgals9,Sirt1,Mmp9,Ccl22,Plcl2,Arel1,Serpina3g,Tspo,Bst1,Hspa1a,Cenpe,Plpp3,Map2k4,Ppp1r15b,Il10,Cx3cr1,Irf1,Klhl25,Phlpp1,Fas,Nsd3,Mtcp1,Sema4c,Serpinb2,Edn1,Dnaja1,Prkar2b,Mmp14,Irf4,Dtx3l,Svbp,Mvp,Serpinb6b,Rnf14,Stk40,Mul1,Ripk2,Lrp4,Ifna5,Mthfr,Traf2,Nek6,Usp25,Ldlr,Jarid2,Casp1,Hap1,Ccne1,Casp4,Marco,Serpinb9b,Gfi1,Il18,Zc3h12a,Ythdf1,Rffl,Inpp5b,Dusp6,Sdc4,Casp8,Cdkn1a,Tnfsf10,Acvrl1,Rnf19a,Nck1,Ifna6,Tmem67,Mefv,Agrn,Il12b,Samsn1,Ednrb,Lox,Mid1,Tnfrsf8,Dusp1,Acvr1b,Bmp2,Cpeb4,Prkce,Cdk5r1,Nfkb1,Tnfrsf14,Ppp2r5a,Ifnar1,Tlr3,Plat,Isg15,Il1b,Pmaip1,Polr2g,Trib3,Ifna1,Mlkl,Btg2,Slfn1,Eif2ak2,Socs1,Stat5a,Map3k8,Socs3,Ifna2,Rbpms,Plekhn1,Rnf34,Sco1,Mllt6,Psmb8,Birc3,Ppp1r14b,Ccl2,Psmb9,Adrb2,Gtpbp2,Arrdc4,Nfkbia,Il15,Csf1,Nupr1,Dnajb2,Ccng2,Gsap,S1pr2,Antxr1,Hspa2,Nr1h3,Ptk2,Ptpn2,Fzd5,Pdgfrb,Ccl8,Tnfsf15,Vcan,Flt1,Lif,Map2k1,Eif4g2,Stat2,Fpr2,Odc1,Bcl2l11,Peli1,Rictor,Tnfaip3,Inhba,Errfi1,Tlr6,Jak2,Timp1,Sphk1,Nlrp3,Scimp,Rgs14,Rnf139,Tnfrsf1b |
| 1.082e-48 | -110.45 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN | 180 | 88 | 15632 | 1249 |
Ppm1k,Gch1,Uba7,Il12b,Kdm6b,Plaur,Clic4,Tnfsf10,Cd40,Otud1,Axl,Tapbp,Mlkl,Setdb2,Dtx3l,St3gal6,Traf1,Stat2,Ddx58,Pml,Itga4,Gbp2,Plekha2,Ccrl2,Sirt1,Timeless,Slc25a22,Ppa1,Tmod3,Tmem219,Tagap,Tiparp,Znfx1,Agrn,Cd200r4,Tra2a,Il6,Abcb1a,Ccnd2,Lrp8,Atf3,Rars,Nfkbiz,Angpt1,Ppfibp1,Vps54,Fzd5,Cd274,Ccl5,Stxbp3,Trim26,Frmd4a,Gpr85,Inpp1,Mitd1,Arid5a,Arhgef3,Tnf,Hdac1,Treml2,D1Ertd622e,Sat1,Pigv,Rnf139,Csrnp1,Prrg4,Ch25h,Mvp,1600014C10Rik,Usp12,Trim14,Ddx4,Asb13,Parp11,Trib1,Oasl1,Cpeb4,Max,Jak2,Tmem184b,Gsdmd,Optn,Katna1,Rbl1,Enpp4,Spred1,Tspo,Zbtb5 |
| 1.136e-48 | -110.40 | regulation of cellular metabolic process | biological process | GO:0031323 | 5484 | 618 | 20694 | 1406 |
Mdm2,Pdgfc,Psme1,Pttg1,Mapkapk2,Fubp1,Dram1,Tal2,Hmga2,Ppp2r3a,Hk2,Casp3,Gja1,Itgav,Ikbkg,Crlf3,Pcx,Zmynd15,Relb,Tnfsf14,Ccnd1,Psmd10,Nr4a3,Plk2,Thbs1,Prdm9,Cd34,Grk3,N4bp1,Prnp,Fbxo4,Rel,Ctsc,Il6,Kdm4a,Psme2,Ccnd2,Itga5,Hif1a,Ppp6r1,Ciita,Sap30,Cflar,Dusp8,Mamld1,Jag1,Bcl6,Dusp4,Mmp25,Gdf15,Ppp1r15a,Cst7,Rcan1,Cgas,Il1rn,Txn1,Kdm6b,Spred3,Gadd45b,Kmt5a,Dnajb4,Eno1,Zhx2,Notch2,Pmepa1,Egr1,Rgcc,Zfp281,Ift57,Irgm1,Mafk,Met,Serp1,Myd88,Gch1,Arid5a,Fcgr2b,Nlrc5,Ubash3b,Egr2,Kdr,Gfpt1,Cacna1d,Kitl,Cx3cl1,Mdfic,Optn,Pou2f2,Swap70,Ranbp2,Mndal,Hat1,Crkl,Prdx5,Bcor,Stat1,Spint2,Nlrc4,Trib1,Cycs,Cd200,Maff,Adar,Cysltr2,Ripk3,Tnks1bp1,Egr3,Src,Stat3,Hck,Tfec,Hcls1,Sec24a,Klrk1,Pdgfb,Ak4,Mafg,Ptafr,Lpar1,Batf2,Serpina3f,Myc,Pde5a,Htr2a,Dcp1a,Plagl2,Ppp4r2,Rnf19b,Zeb1,Ccl9,Oas1b,Pde1b,Klf2,Csrnp1,Birc2,Dusp16,Spry2,Aff1,Slc9a1,Fcgr1,Tlr9,Pf4,Apaf1,Spic,Maml2,Ezr,Parp14,Ddit4,Scyl2,Ppp2r1b,Mecp2,Phactr4,Vegfc,Dcun1d3,Iigp1,Cenpj,Cxcl1,Glipr2,Hopx,Ell2,Ccl7,Fam20c,Arf4,Klf3,Ier3,Trim13,Hp,Irf8,Acsl5,Pik3r6,Hhex,Helz2,Ptch1,Htr2b,Lmo4,Lyn,Slc7a11,Tnip1,Ncoa7,Ahr,Ifi209,Clcf1,Fam72a,Cd38,Timeless,Hspa1b,Fam129a,Tank,Cdyl,Dusp2,Atm,Tent4a,Cd80,Higd1a,Acsl1,Bcl2a1d,Fos,Ankib1,Ahrr,Rnf31,Oas2,Malt1,Actb,Junb,Fabp3,Cd74,C3,Tlr1,Map3k6,Ankrd17,Vrk2,Fgr,Psip1,Larp1,Igf1r,Fignl2,Tshz1,Wars,Phip,Nox1,Nod1,Cdkn2d,Ifnb1,Jdp2,Serpinb9,Rabgef1,Trim14,Ccl5,Pik3r5,Prdm1,Noct,Ccr1,Brwd3,Pml,Ccnj,Eya4,Ago3,Pim2,Ric1,Stat4,Sh3bp4,Syk,Ccl4,Sod2,Fzd1,Oasl1,Ccl3,Ifi204,Irak2,Pid1,Rhoh,Notch1,Uaca,Klf8,Pim1,Hmox1,Tlr2,Map4k4,Icosl,Dyrk2,Gcnt2,Csf3,Tlk2,Nmi,Ptprj,Nfkbie,Ass1,Tnfsf8,Spred1,Htra1,Parp9,Ifi208,Ifna4,Sesn3,Irgm2,Nos2,Tab2,Gbp4,Irak3,Gadd45g,Ctla2a,Zfp36,Cop1,Hivep3,Tent2,Stap1,Trim21,Xrn1,Serpine1,Nfkbid,Radx,Nod2,Lrp8,Hdac1,Plau,S100a8,Hinfp,Acvr1,Plaur,Nr4a1,Tnfsf4,Mov10,Ptger4,Atp2b4,Ets2,Aim2,Adora2a,Rfx5,Mlkl,Btg2,Ifna1,Acp5,Trib3,Pmaip1,Tet2,Polr2g,Il1b,Isg15,Plat,Ifi205,Tlr3,Ifnar1,Tnfrsf14,Ppp2r5a,Oas1g,Nfkb1,Cdk5r1,Prkce,Keap1,Lhx2,Cpeb4,Nmral1,Plek,Zbtb5,Bmp2,Nfkb2,Perm1,Dusp1,Acvr1b,Mid1,Tnfrsf8,Lox,Bnip3,Ifi214,Carhsp1,Samsn1,Ednrb,Tra2a,Agrn,Il12b,Mefv,Tmem67,Brd2,Nck1,Ifna6,Rnf19a,Acvrl1,Tnfsf10,Phf6,Cdkn1a,Ifi207,Casp8,Zfp513,Nampt,Pikfyve,Rbbp8,Etv5,Pla2g4a,Sdc4,Cacybp,Dusp6,Rffl,Ifi211,Sp140,Plac8,Tnfrsf1b,Rnf139,Rgs14,Zc3hav1,Nlrp3,Scimp,Sphk1,Cdyl2,Tcea1,Tlr6,Jak2,Timp1,Errfi1,Irf7,Tnfaip3,Pgk1,Inhba,Rictor,Ddx58,Dek,Traf5,Hmgn3,Cox17,Nr3c1,Peli1,Bcl2l11,Fpr2,Stat2,Eif4g2,Pdk3,Map2k1,Lif,Flt1,Oas1a,Vcan,Arg2,Tnfsf15,Wdr43,Psma6,Ccl8,Fzd5,Ptpn2,Cebpd,Pdgfrb,Ptk2,Kdm5b,Fosb,Etv6,Tle3,Nr1h3,Hspa2,Spen,Antxr1,Ifrd1,S1pr2,Rhoq,Ccng2,Gsap,Dnajb2,Nupr1,Csf1,Il15,Med21,Slamf8,Dcp2,Nfkbia,Adrb2,Arrdc4,Gtpbp2,Ppp1r14b,Oas3,Batf,Ccl2,Birc3,Mllt6,Sco1,Rbpms,Plekhn1,Rnf34,Socs3,Ifna2,Arid4a,Aebp2,Map3k8,Stat5a,Socs1,Slfn1,Plagl1,Eif2ak2,Pnpt1,Ccl22,Plcl2,Etv3,Mmp9,Sirt1,Lgals9,Sqstm1,Acod1,Riox2,Cav1,Klf7,Osm,Myadm,Pbx1,Trim30a,Spire1,Rapgef2,Hsph1,Tax1bp1,Mier3,Spn,Plscr1,Dusp5,Nfxl1,Adora2b,Marf1,Rap2c,Ppp2r2a,Cyfip1,Nfil3,Klf6,Slpi,Casz1,Mmd,Bcl9,Ier2,Traf1,Oasl2,Ksr1,Ptgs2,Ifi213,Lipg,Max,Aida,Arid5b,Parp3,Pou3f1,Gclc,Mycl,Mtdh,Rbl1,Cd40,Igf2bp2,Dr1,Uchl1,Irs2,Kat2b,Jmjd6,Icam1,Mxd1,Il27,Prdx1,Ikzf1,Angpt1,Atf3,Caml,Ccl12,Rasgrp1,Parp10,Sertad3,Taf4b,Tpx2,Cited2,Bambi,Jun,Pcgf5,Tcf4,Fam162a,Plk3,Tnf,Mapkbp1,Daxx,Il1a,Ythdf1,Zc3h12a,Il18,Gfi1,Sele,Chmp4b,Serpinb9b,Nfkbib,Foxp4,Marco,Casp4,Trim26,Nfkbil1,Hivep2,Ifi203,Hap1,Ccne1,Jarid2,Casp1,Smg7,Ldlr,Il18rap,Usp25,Nek6,Traf2,Mthfr,Ifna5,Hlx,Mul1,Ripk2,Lrp4,Stk40,Znfx1,Rnf14,Serpinb6b,Mvp,Dtx3l,Svbp,Irf4,Mmp14,Sav1,Med13,Dnaja1,Prkar2b,Edn1,Serpinb2,Sema4c,Resf1,Mtcp1,Hmga1,Nsd3,Rubcnl,Fas,Phlpp1,Klhl25,Gk,Irf1,Cx3cr1,Dach1,Il10,Irf2,Ppp1r15b,Map2k4,Plpp3,Hspa1a,Cmklr1,Cenpe,Bst1,Tspo,Serpina3g |
| 2.161e-48 | -109.75 | regulation of nitrogen compound metabolic process | biological process | GO:0051171 | 5153 | 591 | 20694 | 1406 |
S100a8,Acvr1,Plaur,Hinfp,Nr4a1,Tnfsf4,Hdac1,Aim2,Adora2a,Mov10,Ptger4,Atp2b4,Ets2,Cop1,Hivep3,Irak3,Gadd45g,Ctla2a,Zfp36,Serpine1,Nfkbid,Radx,Nod2,Lrp8,Tent2,Stap1,Trim21,Xrn1,Tlk2,Nmi,Ptprj,Ass1,Nfkbie,Tnfsf8,Map4k4,Icosl,Csf3,Gcnt2,Parp9,Ifi208,Ifna4,Irgm2,Nos2,Tab2,Gbp4,Spred1,Htra1,Pid1,Notch1,Tiparp,Irak2,Pim1,Tlr2,Hmox1,Uaca,Klf8,Ccr1,Pml,Brwd3,Eya4,Ccnj,Ago3,Pim2,Pik3r5,Prdm1,Noct,Sod2,Fzd1,Oasl1,Ccl3,Ifi204,Ric1,Stat4,Syk,Ccl4,Fabp3,Cd74,C3,Tlr1,Rnf31,Oas2,Malt1,Actb,Junb,Ifnb1,Nod1,Cdkn2d,Jdp2,Rabgef1,Serpinb9,Ccl5,Trim14,Map3k6,Vrk2,Fgr,Psip1,Larp1,Igf1r,Fignl2,Tshz1,Nox1,Wars,Phip,Dusp2,Fam72a,Cd38,Timeless,Hspa1b,Tank,Cdyl,Fam129a,Bcl2a1d,Fos,Ahrr,Ankib1,Tent4a,Atm,Cd80,Higd1a,Acsl1,Trim13,Irf8,Pik3r6,Hhex,Arf4,Klf3,Ier3,Lyn,Tnip1,Ncoa7,Slc7a11,Ifi209,Ahr,Clcf1,Helz2,Ptch1,Lmo4,Htr2b,Maml2,Ezr,Parp14,Ddit4,Fcgr1,Slc9a1,Tlr9,Pf4,Apaf1,Spic,Glipr2,Ell2,Hopx,Ccl7,Mecp2,Ppp2r1b,Vegfc,Phactr4,Dcun1d3,Cenpj,Ppp4r2,Rnf19b,Ccl9,Zeb1,Oas1b,Pde5a,Myc,Htr2a,Dcp1a,Plagl2,Spry2,Aff1,Pde1b,Klf2,Csrnp1,Birc2,Dusp16,Tfec,Hcls1,Sec24a,Tnks1bp1,Egr3,Src,Hck,Stat3,Lpar1,Serpina3f,Batf2,Klrk1,Ak4,Pdgfb,Mafg,Ptafr,Mndal,Pou2f2,Swap70,Trib1,Cycs,Cd200,Maff,Adar,Cysltr2,Ripk3,Hat1,Crkl,Prdx5,Bcor,Stat1,Spint2,Nlrc4,Gch1,Arid5a,Fcgr2b,Zfp281,Ift57,Mafk,Met,Serp1,Myd88,Cacna1d,Kitl,Cx3cl1,Mdfic,Nlrc5,Ubash3b,Egr2,Kdr,Cst7,Rcan1,Cgas,Txn1,Kdm6b,Il1rn,Spred3,Gadd45b,Bcl6,Dusp4,Mmp25,Gdf15,Ppp1r15a,Zhx2,Notch2,Egr1,Pmepa1,Rgcc,Kmt5a,Dnajb4,Eno1,Rel,Ctsc,Plk2,Thbs1,Prdm9,N4bp1,Grk3,Cd34,Prnp,Fbxo4,Ppp6r1,Ciita,Sap30,Cflar,Dusp8,Mamld1,Jag1,Il6,Kdm4a,Psme2,Ccnd2,Hif1a,Itga5,Pttg1,Mapkapk2,Fubp1,Tal2,Ppp2r3a,Hmga2,Mdm2,Pdgfc,Psme1,Crlf3,Zmynd15,Relb,Tnfsf14,Ccnd1,Psmd10,Nr4a3,Casp3,Itgav,Gja1,Ikbkg,Dach1,Cx3cr1,Il10,Irf2,Ppp1r15b,Map2k4,Phlpp1,Klhl25,Irf1,Tspo,Serpina3g,Plpp3,Cenpe,Hspa1a,Cmklr1,Bst1,Mmp14,Sav1,Med13,Dtx3l,Svbp,Irf4,Mtcp1,Hmga1,Nsd3,Fas,Dnaja1,Prkar2b,Serpinb2,Edn1,Sema4c,Resf1,Ifi203,Hap1,Ccne1,Jarid2,Casp1,Ldlr,Smg7,Il18rap,Casp4,Nfkbil1,Trim26,Hivep2,Hlx,Mul1,Ripk2,Lrp4,Stk40,Znfx1,Rnf14,Mvp,Serpinb6b,Usp25,Nek6,Traf2,Mthfr,Ifna5,Gfi1,Serpinb9b,Ythdf1,Zc3h12a,Il18,Nfkbib,Foxp4,Marco,Atf3,Caml,Ccl12,Rasgrp1,Parp10,Sertad3,Taf4b,Mxd1,Il27,Prdx1,Ikzf1,Angpt1,Tcf4,Jun,Pcgf5,Fam162a,Plk3,Mapkbp1,Tnf,Daxx,Il1a,Tpx2,Cited2,Bambi,Parp3,Pou3f1,Gclc,Lipg,Max,Aida,Arid5b,Uchl1,Kat2b,Jmjd6,Icam1,Mycl,Mtdh,Cd40,Rbl1,Igf2bp2,Dr1,Adora2b,Nfxl1,Rap2c,Ppp2r2a,Rapgef2,Hsph1,Tax1bp1,Spn,Mier3,Plscr1,Dusp5,Mmd,Bcl9,Ier2,Traf1,Ksr1,Oasl2,Ptgs2,Ifi213,Nfil3,Cyfip1,Klf6,Slpi,Casz1,Lgals9,Plcl2,Arel1,Ccl22,Etv3,Mmp9,Sirt1,Cav1,Klf7,Osm,Pbx1,Myadm,Trim30a,Spire1,Sqstm1,Samd9l,Acod1,Riox2,Psmb8,Birc3,Mllt6,Sco1,Med21,Psmb9,Arrdc4,Gtpbp2,Dcp2,Nfkbia,Adrb2,Ppp1r14b,Oas3,Ccl2,Batf,Aebp2,Map3k8,Stat5a,Socs1,Plagl1,Eif2ak2,Slfn1,Pnpt1,Plekhn1,Rbpms,Rnf34,Socs3,Ifna2,Arid4a,Ptk2,Kdm5b,Etv6,Fosb,Tle3,Nr1h3,Ccl8,Ptpn2,Fzd5,Pdgfrb,Cebpd,Ccng2,Gsap,Dnajb2,Nupr1,Csf1,Il15,Hspa2,Spen,Antxr1,Ifrd1,S1pr2,Rhoq,Fpr2,Odc1,Stat2,Eif4g2,Pdk3,Map2k1,Nr3c1,Peli1,Bcl2l11,Tnfsf15,Wdr43,Psma6,Lif,Flt1,Oas1a,Vcan,Rgs14,Zc3hav1,Scimp,Nlrp3,Ifi211,Plac8,Sp140,Tnfrsf1b,Rnf139,Irf7,Tnfaip3,Inhba,Rictor,Ddx58,Dek,Traf5,Hmgn3,Sphk1,Cdyl2,Tcea1,Jak2,Tlr6,Timp1,Errfi1,Cdkn1a,Phf6,Ifi207,Zfp513,Nampt,Casp8,Rbbp8,Etv5,Sdc4,Nck1,Ifna6,Rnf19a,Acvrl1,Tnfsf10,Rffl,Inpp5b,Dusp6,Agrn,Il12b,Mefv,Ifi214,Carhsp1,Samsn1,Ednrb,Tra2a,Tmem67,Brd2,Zbtb5,Bmp2,Cpeb4,Lhx2,Nmral1,Tnfrsf8,Mid1,Lox,Nfkb2,Perm1,Dusp1,Acvr1b,Trib3,Pmaip1,Polr2g,Tet2,Il1b,Isg15,Rfx5,Mlkl,Btg2,Ifna1,Acp5,Tnfrsf14,Ppp2r5a,Oas1g,Nfkb1,Cdk5r1,Prkce,Keap1,Plat,Ifi205,Tlr3,Ifnar1 |
| 2.342e-48 | -109.67 | GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN | 173 | 86 | 15632 | 1249 |
Mndal,Lap3,Ifi211,Xaf1,Tdrd7,Oasl1,Ifi204,Ifit3b,Jak2,Ccl4,Plac8,Eif2ak2,Gadd45b,Parp14,S1pr2,Rin2,Parp9,Ddx60,Fpr2,Ifi214,Gmppb,Rtp4,Phf11a,Ifi207,Slfn5,Olr1,Ccr1,Irf7,Parp12,Atp10a,Kitl,Epsti1,Acp2,Sp110,Tnf,Phf11b,Ifit2,Ifi209,Oas3,Ifi44,Dhx58,Rsad2,Usp18,Ifih1,Cd38,Ncoa7,Abtb2,Ifit3,Plscr1,Oas1a,Ifi203,Stat1,Phf11d,Zcchc2,Ifit1bl1,Ccl12,Znfx1,Il4i1,Samd9l,Adar,Pnpt1,Zbp1,Phf11c,Tap1,Ifit1bl2,Rgl1,Gch1,Ube2l6,Ifi208,Nmi,Wars,Oas2,Herc6,Smox,Oas1g,Cxcl10,Il1rn,Tnfsf10,Cmpk2,Axl,Ifi213,Ifi205,Gpr84,Ddx58,Isg15,Dtx3l |
| 3.105e-48 | -109.39 | GO_RESPONSE_TO_CYTOKINE | MSigDB lists | GO_RESPONSE_TO_CYTOKINE | 660 | 174 | 15632 | 1249 |
Ass1,Eif2ak2,Ifnb1,Nfkb1,Casp8,Psme2,Trim21,Csf1,Ccl4,Jak2,Nfil3,Tnf,Traf2,H2-Q6,Gbp9,Rsad2,Sele,Cd74,Cd14,Ccl5,Flrt2,Trim26,Cxcl2,Il12rb1,Tlr3,Il2rg,Irak2,Nfkb2,Vcam1,Ccl12,Cx3cr1,H2-Q4,Nfkbia,Jun,Ccl2,Il6,Ccr3,Il18bp,Lrp8,Mapkapk2,Il4ra,Etv3,Ccl22,Ifna1,Samhd1,P2ry2,Tnfsf14,Plscr1,Ccrl2,Socs3,Il13ra1,Ebi3,Tnfsf4,Acsl1,Irf1,Hcls1,Ifnar1,Axl,Timp1,Psmb9,Pde1b,Pml,H2-Q7,Psme1,Sphk1,Icam1,Daxx,Gch1,Ifit1bl2,Junb,Cd86,Tnfsf15,Tyk2,Il12b,Ptgs2,Il15ra,Ifna5,Mid1,Fas,Cx3cl1,Tnfrsf1b,Nos2,Pid1,Rel,Isg20,Il18rap,Xaf1,Trim56,Oasl1,Ifit3b,Stat5a,Ifit2,Csf3r,Oas3,Stat3,Aim2,Psmb10,Myd88,Ifna2,Irak3,Ccl3,Cd38,H2-Eb1,Ccr1,Osm,Irf7,Cd274,H2-Aa,Psmb6,Ripk2,Ikbke,Cxcl1,Keap1,Ptges,Il1b,Flrt3,Ifit1bl1,Fos,Psmd10,Edn1,Irf4,Egr1,Fcgr1,Pnpt1,Adar,Ciita,Tnfrsf14,Ccne1,Birc3,Psmb8,Ifit3,Irf8,Sirt1,Oas1a,Stat1,Ifi35,Mefv,Clcf1,Xcr1,Socs7,Src,Cd40,Birc2,Gbp4,Cish,Casp3,Psma6,Mthfr,Itga4,Irf2,Isg15,St3gal6,Socs1,Trim12c,Stat2,Hif1a,Il1a,Tnfrsf8,Relb,Gbp2,Hck,Klf2,Ifna6,Oas2,Csf3,Oas1g,Zc3h12a,Ptger4,H2-Ab1,Ptafr,Cxcl10,Cmklr1,Trafd1,Pf4 |
| 3.977e-48 | -109.14 | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | 94 | 64 | 15632 | 1249 |
Adar,Ifi207,Tap1,Atf3,Mapkapk2,Ifi214,Fcgr2b,Ifrd1,Nfkbia,Eif2ak2,Sqstm1,Sod2,Bcl2a1b,Msr1,Cited2,Ets2,Cflar,Tnip1,Hcls1,Cdkn1a,Kpna3,Stat1,Ifi204,Odc1,Rcn1,Ier3,Ifi211,Slpi,Ifi203,Tnfrsf1b,Nfkb1,Mndal,Casp4,Hck,Rhoc,Myo10,Ier2,Marcksl1,Pml,Icam1,Sat1,Pnp2,Bcl2a1d,Cebpd,Tnf,Ifi213,Txnrd1,Ifi209,Tpst1,Ifi205,Slc2a1,Il1rn,Slfn3,Bcl2a1a,Glrx,Ptgs2,Clec4d,Sap30,Ifi208,Myadm,Gch1,Lcp2,Slfn4,Map2k1 |
| 5.458e-48 | -108.83 | regulation of immune response | biological process | GO:0050776 | 763 | 174 | 20694 | 1406 |
Adora2b,Cd86,Spn,Cd38,Plscr1,H2-M2,Bcl2a1d,Abr,Lgals9,Cd274,Tap1,Dhx58,Pik3r6,H2-T24,Plcl2,Sirt1,Tnip1,Il4ra,Cav1,Lyn,Clcf1,Ifi209,C1rl,Trim30a,Acod1,Ccr1,Rasgrp1,Il27,Angpt1,Rsad2,Ifi204,Tnf,Syk,Rnf135,Stxbp1,Cd74,C3,Parp3,Tlr1,Rnf31,Pde4b,Fpr1,Malt1,Treml2,Ifnb1,Hk1,Rabgef1,Serpinb9,Cd40,Ankrd17,Fgr,Ifi203,Pvr,Il18rap,Nmi,Ptprj,Nfkbil1,Icosl,Irgm2,Mul1,Ifi208,Hlx,Parp9,Ripk2,Tifa,Wdfy1,Traf2,Gfi1,Cd300lf,Irak2,Fgl2,Il18,Zc3h12a,H2-T22,Themis2,Tlr2,Clec4d,Hmox1,B430306N03Rik,Clec4e,H60b,Il10,Tnfsf4,Irf1,Aim2,Cmklr1,Ddx60,C1ra,Nectin2,Irak3,Irf4,Nfkbid,Nod2,Tap2,H2-Q7,Lrp8,Stap1,Samhd1,Cacnb3,Prnp,Il6,Mapkapk2,Il1b,Tnfrsf14,Prkce,Nr4a3,Nfkbiz,Tlr3,Ifi205,H2-T10,Fcgr2b,Arid5a,Myd88,Irgm1,Nlrc5,Cd55,Cgas,Il12b,Ifi214,Bcl6,Cd14,Samsn1,Tnip3,Rgcc,Fpr2,Trim12c,Treml4,Smpdl3b,Peli1,H2-Ab1,Ikbke,Klrk1,Raet1e,Ptafr,Arg2,Usp12,Zc3hav1,Nlrp3,Mndal,Ifi211,Tnfrsf1b,Il12rb1,Irf7,Tnfaip3,H2-Q4,Ripk3,Cd200,Adar,Ddx58,Crkl,Zbp1,Nlrc4,Tlr6,Lcp2,Parp14,Ezr,H2-Q6,Trafd1,Tlr9,Nfkbia,Slamf8,Fcgr1,Stat5a,Socs1,Nr1h3,Clec2d,Phf11a,Ptpn2,Fzd5,Fcgr4,A530064D06Rik,Il15,Dennd1b,Ifih1 |
| 8.456e-48 | -108.39 | binding | molecular function | GO:0005488 | 13028 | 1141 | 20217 | 1400 |
Polr2g,Jarid2,Bcl6,Dusp1,Ap3b1,Ccl7,Tap1,Spsb1,Pcdh7,Spred3,Rabgef1,Mycl,Usp53,Stx6,Inpp5b,Il18,Nfkbiz,Ptch1,Gbp3,Asf1a,Clec4n,Mcmbp,Ascc3,Nqo1,Lif,Col11a2,Pou2f2,Cd180,Hspa1b,Trim56,Bnip3,Cycs,Ddit4,Sat1,Dennd1b,Plac8,Rubcnl,Casp2,Pim1,Nr3c1,Aoah,Htra1,Pdk3,Larp1,Cacybp,Itgav,Nfkbib,Zyx,Homer1,Ifi213,Smc5,Ptprj,Stk40,Stx11,Crbn,Nos2,Slc48a1,Ggct,Cd55,Tnfsf8,Trafd1,Nmi,Irf2,Socs7,Marcksl1,Klf6,Hlx,Dmxl2,Gys1,Spata13,Shfl,Lrp11,Noct,Tor3a,Lgals9,Pde3b,Mitd1,Zfp945,Ly6a,Ebi3,Ppm1k,Serpinb9b,Nox1,Frmd4a,Sdc1,Dst,Etv6,Tifa,Prdm9,Rab21,Gng12,Dock10,P4ha2,Endod1,Arhgef3,Cxcl2,Cd80,Itpkc,Rhoq,Ankrd17,Stat5a,Fubp1,Wars,Pmaip1,Ppfibp2,Ankrd24,Gclc,Usp25,Tmem176b,Apaf1,Frmd6,Traf2,Cutc,Stap1,Hivep2,Ago3,Whamm,Pid1,Sele,Aim2,Clic4,Itga9,Hap1,Tnfaip2,Mob3c,N4bp1,Ripk3,Cpd,Tor1aip2,Adar,Mapkapk2,Fcho2,Rictor,Cyfip1,Rilpl1,Traf3ip2,Anp32a,Jak2,Spire1,Stra6l,Prnp,Ifit1bl2,Snx2,Lmo4,Arid4a,Fabp7,Dhx58,Cxcl3,Ppa1,Oas2,Dusp2,Znrf3,Ccl3,Trib3,Dtnb,Acpp,D16Ertd472e,Gbp4,Radx,Glipr2,Lnpep,Ehd1,Birc3,Fzd1,Dio2,Dusp6,Diaph2,Gtpbp2,Tlr1,Hmga1,Peli1,Ak4,Enpp4,Znrf1,Irak3,Kitl,Mthfd1l,Sav1,Lacc1,Ralgds,Tbc1d1,Gclm,H2-Ab1,Nampt,Traf1,Casp1,Pgk1,Myo1b,Kctd12,Tspo,Stip1,Rapgef5,Agtrap,Tsku,Ifna1,Ifi204,Rgs14,Ankib1,Cxcl11,Aftph,Egr1,Snn,Adprm,Fmnl2,Lrch1,Ppp1r15a,Ednrb,Tnfrsf14,Mndal,Malt1,Tgfbi,Stard7,Usp18,Tal2,Hk2,Prkce,Max,Rtp4,Rgs1,Dgka,Tagln,Katna1,Notch2,Trim26,Tmem67,Tnfsf15,Prdx5,Themis2,Mmp14,Ikzf1,Sap30,Flrt3,Casp7,Cp,Trem1,Gca,Ifna6,Ext1,Ptk2,Ifit2,Dyrk2,Irgm1,Ahrr,Zswim4,Cop1,Il18bp,Adhfe1,Lrp4,Acvr1b,Hdc,Ifit1bl1,Sell,Psip1,Cxcl1,Sla,Hmox1,Stat3,Mx2,Maff,Ly75,Myc,Oas1b,Mid1,Slfn8,Pdzd11,Rcn1,Triobp,Hilpda,Dck,F11r,Inpp1,Rcan1,Slc2a1,Nck1,Plat,Rcsd1,Marcks,Csf3r,Itga5,Helz2,Nod1,Ccl9,Serpinb9,H2-Q4,Mmp9,Nupr1,Idi1,Ccl2,Clec5a,Plekhf2,Ifi214,Cdc42ep2,Rrbp1,Arrdc4,Tnip1,Plau,Etnk1,Rapgef2,Rnf139,Mxd1,Pttg1,Psma6,Itga4,Nfxl1,Ldlr,Rbbp8,Batf,Hvcn1,Ubash3b,Prkar2b,Scyl2,Akt3,Ube2e1,Stat4,Plekha5,Oasl2,Sphk1,Klf8,Adgrl2,Map4k4,Dcp1a,H2-T24,H2-Eb1,Rab10,Tpst1,Gng4,Trim12c,Lztfl1,Flt1,Ifna5,Zfp36,Csrnp1,Dbnl,Jun,Ifit3,Fabp3,Ccr3,Foxp4,Errfi1,Trim21,Papss2,Scimp,Sco1,Notch1,Reps1,Flrt2,Spry2,Csf3,Adora2a,Ddhd1,Parp14,Tmsb10,Lipe,Slc31a2,Pdss1,Pla2g4a,Carmil1,Phyh,Cflar,Adrb2,Bcl9,Oasl1,Ptpn2,9130023H24Rik,Ep400,Dek,Tdrd7,Arg2,Pde4b,S1pr2,Car13,Gnb4,Cnot4,Gramd1a,Il13ra1,Cd74,Actb,Med21,Hivep3,Taf4b,Sdc2,Tulp3,Cmpk2,Tcf4,Hhex,Zmynd15,Grina,Acp2,Kmt5a,Dock4,Gch1,Marf1,Resf1,Irf4,Rbms1,Pim2,Vcan,Eno2,Ppp2r1b,Cd69,Kif9,Clec2d,Ifih1,Plcl2,Vezt,Ccr1,Lox,Ciapin1,Tnf,Tank,Acsl5,Layn,Trim14,Map2k4,Pou3f1,Hmgn3,Casz1,Gfpt1,Arl4a,Tapbpl,Mefv,Zc3h12c,Hck,Mt2,Tra2a,Irf7,Pstpip2,Tnfsf9,Phip,Sde2,Xaf1,Ric1,Xrn1,Parp9,Itgal,Aebp2,Sp100,Phlpp2,Ppm1l,Vasp,Stau1,Mafg,Vps54,Clcn7,Psmb9,Zeb1,Rffl,Traf5,Cst7,Ube2l6,Zup1,Stxbp1,Socs3,Dennd2a,Arf4,Lap3,Tbc1d13,Tut7,Isg20,Ctu1,Tnfaip3,Magohb,Ncoa5,Serpine1,Ifi208,Herc6,Ppp2r3a,Col18a1,Ppp4r2,Micall2,P4ha1,Ociad1,Ikbke,Wdfy1,Txn1,Cemip2,Acvrl1,Bcl2a1b,Rnd1,Cenpj,Stard5,Spred1,Ch25h,Map2k1,Gsap,Ifrd1,Pnp2,Alas1,Mpp7,Nek6,Arid5a,Nsmaf,Dnase1l3,Csrp1,Mtus1,Nes,Plagl1,Rnd3,Tcea1,Map3k8,Bmp2,Tpm4,Nrp2,Mt1,Abcb1a,Ier2,Nlrc5,H2-Q7,Ifnar1,Gsr,Trip10,Slc31a1,Bcor,Smg7,Rnf114,Fnbp1l,Me1,Ifit3b,Igsf8,Cav1,Nectin2,Eef1e1,Rnf19b,Pikfyve,Rnf31,Sec24b,Oas3,Trim12a,Mdfic,Hcar2,Nfkbid,H2-M2,Cd200r4,Il10,Cxcl9,Rrs1,Tnks1bp1,Egr2,Marco,Aida,Osm,Cd164,Ncoa7,Gbe1,Icosl,Abtb2,Crlf3,Sgk3,Sdc4,Iigp1,Sesn3,Hsd17b12,C1ra,Src,Ctla2b,Hspa2,Itpr1,Crim1,Arl5c,Stat1,Nfkbia,Ifna2,Igf1r,Trim34a,Calcrl,Col27a1,Pmepa1,Fut8,Evl,Hat1,Il12b,Med13,Tpi1,Pik3cd,Cxcl14,Svbp,Plekha2,Pbx1,Fas,Swap70,Plod2,Ccl22,Sema4a,Acp5,Slc25a25,Dtx2,Prdx1,Gbp2,Apol9b,Ppp6r1,Mob3b,Vrk2,Oas1a,Daxx,Casp8,Dennd6b,Ift22,Mocs1,Rhoh,Fos,Cd200,Psme1,Il27,Bcl2l11,Cpeb4,Cyth3,Hp,Plekhn1,Slamf8,Pf4,Psd4,Ifi207,Il1a,Tgs1,Ranbp2,Junb,Gmppb,Milr1,Ddx58,Saa3,Slc9a1,Il6,Ktn1,Ddx60,Ift57,Rhoc,Arhgap26,A530064D06Rik,Pdgfc,Fbxo4,Ets2,Phactr4,Clec4e,Nfil3,Hcls1,Tuba4a,Rbms2,Atf3,Dr1,Sema3c,Hmgcs1,Rhof,Ccnd2,Ube2f,Tlr9,Mtdh,Lpcat2,Bbx,Cited2,Rasgrp1,Rsad2,Gng11,Kdm4a,Tlr3,Ezr,Lipg,Srxn1,Procr,Tfec,Mecp2,Tor1aip1,Zfp319,Tab2,Pml,Pilrb1,C3,Zbp1,Sbds,Cdyl,Lcp2,Pim3,Rel,Prrg4,Plaur,Hinfp,Gpc1,Psd,Cdkn1a,Kcnj2,Kif3c,Odc1,Tnfrsf1b,Eif2ak2,Rab20,Eno1,Slc39a13,Pdgfrb,Gbp8,Dync1h1,Osbpl3,Mapkbp1,Hdac1,Hk1,Phf11a,Acsl1,Nkiras1,Keap1,Dtx3l,Dgkh,Mthfr,Cd38,Arid5b,Atp10a,Il12rb1,Kdr,Klra2,Zfp40,Tmem178,Myd88,Nr4a3,Srm,Myo10,Nsd3,Dach1,Sqstm1,Cd302,Vegfc,Ythdf1,Clcn5,Txnrd1,Flnb,Eya4,Tmod3,Nfkb2,Tiparp,Eva1b,Eif4g2,Tlk2,Smpdl3b,Clcf1,Zc3h7a,Igsf9,Sec24a,Cnp,Tomm70a,Prpf4,Abcc5,Insl6,Sp110,Cdyl2,Ppp2r5a,Vcam1,Ctsc,Isg15,Cnn3,Egr3,Klf7,Parp12,Plod3,Slfn5,Phlda1,Prag1,Hk3,Hspa1a,H2-T10,Mcm10,Clec4d,Olr1,Htr2a,Ptafr,Ampd3,Tmem176a,Klf3,Adam19,Tapbp,Ccl5,Tnc,Nt5c3,Mgat1,Tarm1,Ifi209,Btg2,Csf1,Lyn,Arl5b,Caml,Nod2,Socs1,Ddx4,Pla2g7,Spen,Cd34,Igf2bp2,Cers6,Gja1,Atp13a1,Nr1h3,Gpsm2,Sp140,Adgrg6,Phgdh,Ier3,Cx3cl1,Sipa1l1,Rims3,Ifi205,Cd86,Ksr1,Bcl2a1a,Ifit1,Kif5c,Ccl12,Atp2b4,Msantd3,Slc16a1,Cd274,Mvp,Ahr,Slfn1,Lcn2,Zcchc2,F10,Zc3hav1,Ccdc88b,Yju2,Nmral1,Adgb,Rap2c,Gpd2,Stat2,Rras2,Mx1,Adap2,Trim13,Mier3,Tnip3,H60b,Il2rg,G3bp2,Tpx2,Fam20c,Tgtp1,H2-T22,Aff1,Cebpd,Il15,Crkl,Riox2,Plekha4,Gbgt1,Axl,Ntng2,Prdm1,Atm,Pde1b,Mafk,Hsph1,Trim36,Gsdmd,Mdm2,Asah2,Angpt1,Dcp2,Ppp1r12b,Srgn,Jdp2,Il15ra,Sgcb,Ass1,Kmo,Trmt1l,S100a8,Cdc42ep4,Edn1,Psme2,Hsd17b7,Rnf14,Kdm5b,Osgin2,Ccl8,Zfp513,Phlpp1,Ifnb1,Fscn1,Scn1b,Cox17,Lhx2,Msr1,Cish,Irak2,Fcgr1,Setdb2,Stxbp3,Pdgfb,Pcgf5,Sh3bgrl2,Fzd5,Tnfsf4,Syne2,Hif1a,Gadd45g,Acvr1,Palld,Rnf34,Klrk1,Nfkbie,Rbm43,Nlrp3,Ifna4,Samhd1,Vasn,Ltbp2,Fchsd2,Phf6,Agrn,Cd14,Casp3,Rab9,Pde5a,Asap3,Slfn9,Ppp2r2a,Hopx,Daam1,Irs2,Carhsp1,Zfp281,Tshz1,Egln3,Lnpk,Ube2e2,Abcc1,B4galt4,Slc4a7,Htr2b,Ptges,Rhbdf2,Ccnj,Extl2,Klf2,Plagl2,Rab32,H2-Q6,Itgb8,Bambi,Uaca,Cx3cr1,Dnajb4,Gda,Phf11d,Zc3h12a,Ptgs2,Gbp7,Pvr,Hmga2,Irf8,Glrx,Tent4a,Ahsa1,Sema4c,Irgm2,Nxf1,Bfar,Snapc1,Plscr1,Ccnd1,Trib1,Cacnb3,Tet2,Relb,Grk3,Rpgrip1l,Zhx2,Bcl2a1d,Irf1,Tagap,Slamf7,Rhou,Tlr6,Gem,Gna15,Top3a,Mark2,Plek,Mcm6,Cnn2,Syk,Jmjd6,Siglece,Mov10,Rfx5,Timp1,Prkx,Met,Rars,Ikbkg,Asns,Sertad3,Cd300lf,Pgm1,Fgr,Pgs1,Cdk5r1,Tent2,Tap2,Cep350,Mcm9,Tyk2,H3f3b,Ccne1,Tle3,Snx10,Plpp3,Cgas,Tnfsf14,Trim30a,Dcun1d3,Ripk2,Mthfd2,Fpr2,Rbpms,Pkp4,Icam1,Mul1,Ciita,Pdlim7,Golga3,Cd40,Rnf19a,Piezo1,Psmd10,Pnpt1,Rab19,Il1rn,Tnfsf10,Parp10,Oas1g,Sh3bp4,Gdf15,Ubr4,Birc2,Batf2,Pde7b,Pilra,Tlr2,Rgcc,Cxcl10,Map3k6,Adgre4,Cept1,Pfkl,Nlrc4,Dusp16,Rab11fip1,Rnf24,Plk3,Scarf1,Rbl1,Timeless,Thbs1,Apba1,Kat2b,Ccng2,Apobec3,Znfx1,Fpr1,Rsbn1,Pcx,Cacna1d,Pilrb2,Mlkl,Dnaja1,Jag1,Pdpn,Ccrl2,Brd2,Fcgr4,Atp11a,Dync1i2,Trip13,Chd9,Morc3,Sirt1,Tax1bp1,Dnaja2,Sik3,Nr4a1,Plk2,Pik3r6,Chmp4b,Esd,Azi2,Lrp8,Optn,Treml4,H2-Aa,Spn,Cenpe,Denr,Slpi,Inhba,Lpar1,Sinhcaf,Sod2,Spic,Gfi1,Ccl4,Rgl1,Ldha,Dnajb2,Ifi203,Etv5,Nectin4,Il1b,Mmp13,Mppe1,Rac3,Gadd45b,Usp12,Leng9,Cdkn2d,Irgq,Antxr1,Zfp800,Samsn1,Mmp25,Abr,Zbtb5,Gk,Rnf135,Etv3,Kdm6b,P2ry2,Fcgr2b,Xcr1,Casp4,Rab3ip,Raet1e,Il4ra,Ifi211,Nlgn2,Gbp2b,Gbp9,Mllt6,Uchl1,Slc25a12,Kpna3,Rnf145,Nfkb1,Samd9l,Fosb |
| 8.960e-48 | -108.33 | GSE42724_NAIVE_BCELL_VS_PLASMABLAST_UP | MSigDB lists | GSE42724_NAIVE_BCELL_VS_PLASMABLAST_UP | 167 | 84 | 15632 | 1249 |
Nmi,Ube2l6,AA467197,Oas2,Parp12,Uba7,Gch1,Ifit1bl2,Irf7,Ppm1k,Cnp,Tap2,Tnfsf10,Cmpk2,Sp110,Trafd1,Il15ra,Epsti1,Rtn1,Pcgf5,Oas1g,Herc6,Tlr3,Tapbpl,Clec4d,Cxcl10,St7,Batf2,Ifi44,Rsad2,Dhx58,Ddhd1,Sp140,Casp1,Ifit2,Axl,Oas3,Psmb9,Myd88,Mvp,Cd38,Csrnp1,Pml,Psme1,Parp10,Aim2,Gbp3,Trim12c,Ifih1,Isg15,Dtx3l,Ddx58,Stat2,Usp18,Plscr1,Isg20,Trim21,Tdrd7,Xaf1,Oas1a,Lap3,Ifit3,Mov10,Stat1,Oasl1,Ifi35,Ifit3b,Dnajb4,Irf1,Gclm,Parp14,Phactr4,Samd9l,Parp9,Sqstm1,Eif2ak2,Ifit1bl1,Nlrc5,Znfx1,Zbp1,Pnpt1,Tap1,Ddx60,Rtp4 |
| 9.325e-48 | -108.29 | GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP | 159 | 82 | 15632 | 1249 |
Ccrl2,Usp12,Tifa,Pdss1,Il10,Rel,Birc3,Ppp1r15b,Dcun1d3,Cdkn1a,Clcf1,Cflar,Rgs1,Ccl4,Rap2c,Dnajb4,Tnip3,Acsl1,Ier3,Dram1,Ell2,Socs3,Rin2,Kcnj2,Edn1,Dusp2,Il6,Peli1,Ets2,Gadd45b,Hivep2,Nfkbia,Bcl2a1b,Sod2,Pfkfb3,Pim3,Nlrp3,Nfkbiz,Egr1,Inhba,Rapgef2,Csf3,Cxcl2,Maff,Ddit4,Btg2,Arl5b,Cd274,Ppp1r15a,Txn1,Plek,Gch1,Plaur,Il1b,Cxcl1,Bcl2a1a,Ptgs2,Il12b,Map3k8,Il18,Ptger4,Ripk2,Zc3h12a,Dusp5,Bcl2a1d,Rab21,Gpr84,Rbbp8,Dusp1,Stat5a,Tnf,Plekhf2,Gbp2,Tnfaip3,Cd83,Sav1,Il1a,Icam1,Rnd1,Plk3,Csrnp1,Rhoh |
| 1.665e-47 | -107.71 | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_UP | MSigDB lists | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_UP | 189 | 89 | 15632 | 1249 |
Spn,Slfn8,Katna1,Fpr2,Slc30a1,Rtp4,Ddx60,Sgcb,Il15,Tspo,Hdc,Ppp1r15b,Isg20,Ifit3b,Oasl1,Uaca,Lhx2,Oas3,Stat5a,Ifit2,Ddhd1,Rsad2,Rab21,Gbp9,Upp1,Usp18,Ifih1,Gnb4,Irf7,Ccl5,Pde7b,Fam72a,Sap30,Nrp2,Tlr3,Atp10a,Pcgf5,Inpp1,Plat,Mitd1,Ifit1bl1,Nlrc5,Samd9l,Irgm2,Ccl2,Prkce,Ccl22,Samhd1,Slc28a2,Fcgr1,Marco,Ifit3,Abtb2,Hat1,Cd69,Akt3,Timeless,Aida,Sema4a,Actb,Kdr,Cd40,Gpsm2,Gypc,Mlkl,Gbp4,Setdb2,Pnp2,Isg15,Sell,Mthfr,Ifit1,Daxx,Gbp2,Ascc3,Ifit1bl2,Stx11,Ube2l6,Nmi,Ttc39b,Serpinb9,Cxcl10,Tapbpl,Herc6,Il15ra,Cmpk2,Osbpl3,Slfn9,Tnfsf10 |
| 1.953e-47 | -107.55 | GSE17721_0.5H_VS_12H_CPG_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_12H_CPG_BMDC_DN | 185 | 88 | 15632 | 1249 |
Cpeb4,Mthfd2,Dusp16,Nos2,Ppp4r2,Zeb1,Pou2f2,Slamf9,Usp25,Palld,Nck1,Rtp4,Kat2b,Slamf7,Sgcb,Il15,Enpp4,Gramd1a,Crbn,Klf3,Dnaja1,Dusp2,Parp14,Pla2g4a,Slfn8,Ankrd24,Vcan,Fam53c,Arid5b,Mitd1,Gtpbp2,Ppp2r2a,Ccl5,Pdgfrb,Golga3,Tmeff1,Rab10,Parp12,Nupr1,Rnf135,Psmb10,F11r,Zfp281,Stat5a,Slc25a37,Tcf4,Oas3,Cp,Ccng2,Denr,Ebi3,Mefv,Slc25a22,Tnip1,Asf1a,Nlgn2,Gfi1,Birc3,Il10,Ampd3,Eef1e1,Tlr6,Mapkapk2,Pttg1,Tap1,Agrn,Trmt1l,Prkce,Edn1,Rnf19b,Kif3c,Slfn9,Gca,Serpinb2,Acsl5,Cmpk2,Vegfc,Slc7a8,Inpp5b,Lif,Magohb,Socs1,Agtrap,Casp1,Ctu1,Hsph1,Rffl,Rhoq |
| 2.250e-47 | -107.41 | GSE42724_NAIVE_VS_MEMORY_BCELL_DN | MSigDB lists | GSE42724_NAIVE_VS_MEMORY_BCELL_DN | 181 | 87 | 15632 | 1249 |
Pim1,Slfn9,Clic4,Acsl5,5430427O19Rik,Sec24b,Il15ra,Arid4a,Slc4a7,Snx10,Asah2,Ppm1k,Oas2,Itga4,Hlx,Sertad3,Cd83,Bfar,Mapkbp1,N4bp1,Rbbp8,Cd40,Setdb2,Ccdc86,Gpr84,Il13ra1,Tnfsf4,Etnk1,Ankib1,Gbp7,Casp4,Zc3h7a,Cd69,Slc39a14,Nfkbiz,Zyx,Bbx,Ppp2r5a,Ikzf1,Tra2a,4932438A13Rik,Ripk2,Frmd4a,Rcan1,Keap1,Ppp2r2a,Stip1,Pde4b,Golga3,Sap30,Asap3,Ifih1,Cutc,Sgk3,Sav1,Gda,Pdgfc,Batf2,Stat3,1110038F14Rik,D1Ertd622e,Ythdf1,Arhgap26,Dram1,Cpeb4,Sema4c,Map2k4,Ldlr,Rbms1,Wdr43,Dusp16,Lhx2,Ednrb,Cenpj,Plod2,Stx6,Usp12,Dcp2,Sdc4,Spred1,Aff1,Spsb1,Katna1,Lrch1,Slfn8,Parp9,Vcan |
| 2.411e-47 | -107.34 | GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | 194 | 90 | 15632 | 1249 |
Syne2,Zfp36,Psme2,Ifi211,Csf1,Trim21,Trim14,Isg20,Casp8,Lap3,Mndal,Hk1,Ldlr,Jak2,Ifit3b,Ifi204,C3,Oasl1,Dram1,Max,Gclm,Rnf114,Sod2,Zc3hav1,Ifi207,Phf11a,Il15,Rtp4,Ifi214,Ddx60,Fas,Parp12,Irf7,Tap2,Sp110,Cxcl1,Arid5b,Tlr3,Stat3,Oas3,Bcl6,Ifi209,H2-Q6,Phf11b,Myd88,Ifih1,Psmb10,Ifi203,Met,Plscr1,Ogfr,Ifit3,Irf8,Psmb8,Rcn1,Phf11d,Irf1,Stat1,Casp7,Ifi35,Ccl12,H2-Q4,Ifit1bl1,Phf11c,Tap1,Adar,Rars,Maff,Wars,Nmi,Ifi208,Ube2l6,Ifit1bl2,Trafd1,Il15ra,Cxcl10,Rnf19b,Cebpd,Tapbp,C1ra,Ifi205,Psmb9,Ifi213,Gbp2,Socs1,Isg15,Icam1,Ddx58,Pml,H2-Q7 |
| 3.053e-47 | -107.11 | GSE2706_UNSTIM_VS_8H_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_R848_DC_DN | 169 | 84 | 15632 | 1249 |
Batf,Tnfaip3,Relb,Mcoln2,Marcksl1,Traf1,Isg15,Ifih1,Ddx58,Usp18,Ifi44,Itgb8,Sat1,Tnc,Psma6,Ifit2,Tnf,Swap70,Tnfsf10,Thbs1,Plat,Osbpl3,Il1b,Cmpk2,Epsti1,Zc3h12a,Dusp5,Ptger4,Herc6,Cxcl10,Nr4a3,Map3k8,Nmi,Tnfsf15,Oas2,AA467197,Stx11,Inhba,Wars,Rapgef2,Brwd3,Sesn3,Nampt,Txn1,Ifit1bl2,Sipa1l1,Cd274,Slamf7,Il15,Slfn5,Nfkbiz,Etv3,Plagl1,Il6,Parp14,Samd9l,Dusp4,Parp9,Sod2,Gadd45b,Eif2ak2,Ifit1bl1,Nlrc5,Rgs1,Tnfaip2,Pim2,Ptgir,Socs3,Stat1,Dgkh,Casp7,Ebi3,Ifi35,Ifit3b,Isg20,Rasgrp1,Tdrd7,Xaf1,Stat4,Nfkb1,Abtb2,Birc3,Ifit3,Rel |
| 3.390e-47 | -107.00 | response to cytokine | biological process | GO:0034097 | 965 | 198 | 20694 | 1406 |
Stoml1,Tank,Plscr1,Ifi213,Ptgs2,Ifit2,Acsl1,Gbp2b,H2-Eb1,Ifit1,Klf6,Nfil3,Cd274,Axl,Irf8,Il15ra,Sirt1,Etv3,Ccl22,Cxcl11,Ifi209,Il4ra,Osm,Acod1,Asah2,Ccl12,Pml,Ccr1,Zyx,Rab20,Il1a,Ifi204,Ccl3,Tnf,Jun,Ccl4,Stxbp1,Syk,Stat4,Il13ra1,Cd74,Junb,Arid5b,Oas2,Icam1,Ccl5,Cxcl2,Ifnb1,Srm,F830016B08Rik,Gbp8,Il18rap,Stx11,Nmi,Casp1,Xcr1,Jarid2,Ifi203,Csf3,Cdc42ep2,Gbp4,Nos2,Irgm2,Ifna4,Ripk2,Ifi208,Ifna5,Traf2,Cxcl9,Gm4841,Sele,Pid1,Il18,Zc3h12a,Irak2,Cd300lf,Tlr2,Flnb,Cx3cr1,Irf1,Cdc42ep4,Aim2,Serpina3g,Egln3,Shfl,Gbp7,Ccr3,Tgtp2,Zfp36,Gclm,Irak3,Fas,H2-Q7,Igtp,Serpine1,Trim21,Rel,Nrp2,Lox,Saa3,Il2rg,Ciita,Dusp1,9930111J21Rik1,Il6,Isg15,Il1b,Mapkapk2,Acp5,Ifna1,Keap1,Relb,Nfkb1,Ifnar1,Hk2,Ifi205,Gch1,Trim56,Casp8,Ifi207,Myd88,Gpr35,Irgm1,Ifna6,Cx3cl1,Gbp9,Gm5431,Cacybp,H2-Aa,Mefv,Il12b,Il1rn,Cd14,Ifi214,Ifitm1,Egr1,Eno1,Stxbp3,Hcls1,Gbp3,Stat2,Snx10,Stat3,Src,H2-Ab1,Ikbke,Serpina3f,Lrch1,Cxcl10,Xaf1,Pdgfb,Ebi3,Mndal,Tnfrsf1b,Ifi47,Ifi211,Adar,Il12rb1,Cxcl3,Irf7,Timp1,Stat1,Jak2,Crkl,Sphk1,Ifit3,Birc3,Stip1,Ccl2,Nfkbia,Pf4,Evl,Gbp2,Pnpt1,Eif2ak2,Ccl7,Socs1,Stat5a,Cxcl1,Socs3,Ifna2,Iigp1,Vegfc,Eef1e1,Gm4951,Kdm5b,Ccl9,Gm12185,Ccl8,Myc,Il15,Csf1,Spry2,Birc2,Csf3r,Ccrl2,Tgtp1,Pde1b |
| 4.898e-47 | -106.63 | regulation of primary metabolic process | biological process | GO:0080090 | 5300 | 599 | 20694 | 1406 |
Gbp4,Tab2,Nos2,Irgm2,Ifna4,Ifi208,Parp9,Htra1,Spred1,Tnfsf8,Nfkbie,Ptprj,Nmi,Tlk2,Csf3,Gcnt2,Dyrk2,Icosl,Map4k4,Hmox1,Tlr2,Pim1,Klf8,Uaca,Notch1,Pid1,Tiparp,Irak2,Adora2a,Aim2,Ets2,Atp2b4,Mov10,Ptger4,Tnfsf4,Nr4a1,Hinfp,Acvr1,Plaur,S100a8,Hdac1,Lrp8,Nod2,Nfkbid,Radx,Serpine1,Xrn1,Trim21,Stap1,Tent2,Hivep3,Cop1,Zfp36,Ctla2a,Gadd45g,Irak3,Ahrr,Ankib1,Fos,Bcl2a1d,Acsl1,Higd1a,Cd80,Atm,Tent4a,Dusp2,Fam129a,Tank,Cdyl,Hspa1b,Timeless,Cd38,Fam72a,Clcf1,Ahr,Ifi209,Slc7a11,Ncoa7,Tnip1,Lyn,Ptch1,Htr2b,Lmo4,Helz2,Hhex,Pik3r6,Acsl5,Irf8,Trim13,Ier3,Klf3,Arf4,Ifi204,Ccl3,Oasl1,Fzd1,Sod2,Ccl4,Pde3b,Syk,Stat4,Ric1,Pim2,Ago3,Ccnj,Eya4,Pml,Brwd3,Ccr1,Noct,Prdm1,Pik3r5,Trim14,Ccl5,Rabgef1,Serpinb9,Jdp2,Cdkn2d,Nod1,Ifnb1,Phip,Nox1,Wars,Fignl2,Tshz1,Igf1r,Larp1,Psip1,Fgr,Vrk2,Map3k6,Tlr1,C3,Cd74,Fabp3,Junb,Malt1,Actb,Oas2,Rnf31,Batf2,Serpina3f,Lpar1,Ptafr,Mafg,Ak4,Pdgfb,Sec24a,Hcls1,Tfec,Stat3,Hck,Src,Egr3,Tnks1bp1,Ripk3,Cysltr2,Adar,Maff,Cd200,Cycs,Trib1,Nlrc4,Spint2,Stat1,Bcor,Prdx5,Crkl,Hat1,Mndal,Ranbp2,Swap70,Pou2f2,Ccl7,Hopx,Ell2,Glipr2,Cenpj,Dcun1d3,Vegfc,Phactr4,Mecp2,Ppp2r1b,Ddit4,Ezr,Parp14,Maml2,Spic,Pf4,Tlr9,Apaf1,Fcgr1,Slc9a1,Aff1,Spry2,Dusp16,Birc2,Csrnp1,Klf2,Pde1b,Ccl9,Oas1b,Zeb1,Rnf19b,Ppp4r2,Plagl2,Dcp1a,Htr2a,Myc,Pde5a,Jag1,Mamld1,Dusp8,Cflar,Sap30,Ciita,Ppp6r1,Hif1a,Itga5,Ccnd2,Psme2,Kdm4a,Il6,Ctsc,Rel,Fbxo4,Prnp,N4bp1,Grk3,Prdm9,Thbs1,Plk2,Nr4a3,Psmd10,Ccnd1,Tnfsf14,Relb,Zmynd15,Pcx,Crlf3,Ikbkg,Gja1,Itgav,Casp3,Hmga2,Ppp2r3a,Tal2,Fubp1,Mapkapk2,Pttg1,Psme1,Pdgfc,Mdm2,Mdfic,Cx3cl1,Kitl,Cacna1d,Gfpt1,Kdr,Egr2,Ubash3b,Nlrc5,Fcgr2b,Arid5a,Myd88,Serp1,Met,Mafk,Ift57,Zfp281,Rgcc,Egr1,Pmepa1,Zhx2,Notch2,Eno1,Dnajb4,Kmt5a,Spred3,Gadd45b,Il1rn,Cgas,Txn1,Kdm6b,Rcan1,Cst7,Ppp1r15a,Gdf15,Dusp4,Mmp25,Bcl6,Mvp,Serpinb6b,Rnf14,Stk40,Znfx1,Lrp4,Ripk2,Mul1,Hlx,Ifna5,Traf2,Mthfr,Nek6,Usp25,Il18rap,Ldlr,Smg7,Casp1,Jarid2,Ccne1,Ifi203,Hap1,Hivep2,Trim26,Nfkbil1,Casp4,Marco,Foxp4,Nfkbib,Serpinb9b,Gfi1,Il18,Zc3h12a,Ythdf1,Serpina3g,Tspo,Bst1,Hspa1a,Cmklr1,Cenpe,Plpp3,Map2k4,Ppp1r15b,Irf2,Il10,Dach1,Cx3cr1,Irf1,Gk,Klhl25,Phlpp1,Fas,Rubcnl,Nsd3,Hmga1,Mtcp1,Resf1,Sema4c,Serpinb2,Edn1,Prkar2b,Dnaja1,Med13,Sav1,Mmp14,Irf4,Svbp,Dtx3l,Ifi213,Ptgs2,Ksr1,Oasl2,Traf1,Ier2,Bcl9,Mmd,Casz1,Klf6,Slpi,Nfil3,Cyfip1,Ppp2r2a,Rap2c,Nfxl1,Adora2b,Dusp5,Plscr1,Mier3,Spn,Tax1bp1,Hsph1,Rapgef2,Spire1,Trim30a,Pbx1,Myadm,Osm,Klf7,Cav1,Riox2,Samd9l,Acod1,Sqstm1,Lgals9,Mmp9,Sirt1,Etv3,Ccl22,Plcl2,Arel1,Il1a,Daxx,Mapkbp1,Plk3,Tnf,Fam162a,Jun,Pcgf5,Tcf4,Bambi,Cited2,Tpx2,Parp10,Sertad3,Taf4b,Rasgrp1,Caml,Ccl12,Atf3,Angpt1,Ikzf1,Il27,Prdx1,Mxd1,Icam1,Kat2b,Jmjd6,Irs2,Uchl1,Dr1,Igf2bp2,Cd40,Rbl1,Mtdh,Mycl,Gclc,Pou3f1,Parp3,Aida,Arid5b,Max,Lipg,Psma6,Wdr43,Tnfsf15,Vcan,Oas1a,Flt1,Lif,Map2k1,Eif4g2,Pdk3,Stat2,Odc1,Fpr2,Bcl2l11,Peli1,Nr3c1,Traf5,Hmgn3,Dek,Ddx58,Rictor,Inhba,Irf7,Tnfaip3,Errfi1,Timp1,Jak2,Tlr6,Tcea1,Cdyl2,Sphk1,Scimp,Nlrp3,Zc3hav1,Rgs14,Rnf139,Tnfrsf1b,Sp140,Plac8,Ifi211,Pnpt1,Plagl1,Slfn1,Eif2ak2,Socs1,Stat5a,Aebp2,Map3k8,Ifna2,Socs3,Arid4a,Rnf34,Rbpms,Plekhn1,Sco1,Mllt6,Birc3,Psmb8,Oas3,Ccl2,Batf,Ppp1r14b,Arrdc4,Adrb2,Dcp2,Nfkbia,Gtpbp2,Psmb9,Med21,Il15,Hcar2,Csf1,Nupr1,Dnajb2,Gsap,Ccng2,Rhoq,S1pr2,Ifrd1,Antxr1,Hspa2,Spen,Nr1h3,Tle3,Kdm5b,Etv6,Fosb,Ptk2,Pdgfrb,Cebpd,Ptpn2,Fzd5,Ccl8,Lox,Mid1,Tnfrsf8,Acvr1b,Dusp1,Perm1,Nfkb2,Bmp2,Zbtb5,Plek,Nmral1,Lhx2,Cpeb4,Keap1,Cdk5r1,Prkce,Oas1g,Nfkb1,Ppp2r5a,Tnfrsf14,Ifnar1,Tlr3,Ifi205,Plat,Isg15,Il1b,Tet2,Polr2g,Pmaip1,Trib3,Ifna1,Btg2,Ttc39b,Rfx5,Mlkl,Inpp5b,Rffl,Dusp6,Sdc4,Pla2g4a,Etv5,Rbbp8,Nampt,Casp8,Zfp513,Ifi207,Phf6,Cdkn1a,Tnfsf10,Acvrl1,Rnf19a,Ifna6,Nck1,Brd2,Tmem67,Mefv,Agrn,Il12b,Tra2a,Ednrb,Samsn1,Ifi214,Carhsp1 |
| 5.587e-47 | -106.50 | multi-organism process | biological process | GO:0051704 | 2285 | 338 | 20694 | 1406 |
Ankrd17,Nlgn2,Gbp8,Fgr,Mtdh,Cd40,Fndc3a,Cxcl2,Serpinb9,Trim14,Ccl5,Icam1,Nod1,Ifnb1,Malt1,Gsdmd,Junb,Pde4b,Insl6,Oas2,Nt5c3,Tlr1,Cd180,C3,Ccl4,Stxbp1,Rnf135,Cited2,Syk,Oasl1,Tnf,Ifi204,Ccl3,Jun,Trim36,Rsad2,Rab20,Noct,Il27,Prdm1,Ly6a,Prdx1,Ccl12,Ago3,Taf4b,Zyx,Pml,Acod1,Ifit1bl2,Usp18,C1rl,Cxcl11,Parp11,Trim30a,Spire1,Lyn,Cav1,Tnip1,Il4ra,Ier3,Sirt1,Mmp9,Ccl22,Dhx58,Cd274,Hp,Trim13,Lgals9,Irf8,Axl,H2-Eb1,Gbp2b,Ifit1,Ifit1bl1,Ddx4,Atm,Cd80,Slpi,Ptgs2,Ifit2,Abr,Oasl2,Hspa1b,Rab9,Plscr1,Cdyl,Pik3cd,Spn,Cd86,Marf1,Adgrl2,Isg20,Stap1,Trim21,Resf1,Dnaja1,Trip13,Sp110,Rai14,Tap2,H2-Q7,Serpine1,Hmga1,Nod2,Irf4,Zfp36,Dtx3l,Irak3,Nectin2,Ptgir,C1ra,Ddx60,Gbp7,Usp42,Mcoln2,Ptger4,Aim2,Rnf114,Fchsd2,Shfl,Cdc42ep4,Irf1,Hdac1,Acvr1,Irf2,Tnfsf4,S100a8,Cx3cr1,Dach1,H60b,Il10,Marco,Mx1,Nfkbib,Tdrd7,Flnb,Clec4e,Clec4d,Tlr2,Mx2,Slamf7,Zc3h12a,Il18,Irak2,Cd300lf,Slfn2,Chmp4b,Ifi44,Notch1,Rgs1,Gfi1,Cxcl9,Nos2,Tab2,Gbp4,Slfn4,Ripk2,Parp9,Tifa,Ifna4,Irgm2,Clec5a,Cdc42ep2,Casp4,Tut7,Nfkbil1,Trim26,Tlk2,Nmi,Tnfsf8,Stx11,Pvr,Cmpk2,Casp1,Stxbp3,Vcam1,Clic4,Tagap,Tnip3,Notch2,Nectin4,Ednrb,Cd14,Bnip3,Bcl6,Ifitm1,Il1rn,Cgas,Il12b,Mefv,Ccdc88b,Cd55,Plaat3,Gbp9,Nlrc5,H2-Aa,Mt2,Cx3cl1,Inpp5b,Kitl,Spaca6,Irgm1,Myd88,H3f3b,Nck1,Ifna6,Etv5,Gch1,AA467197,Arid5a,Pla2g4a,Fcgr2b,Denr,Trim56,Rtp4,Itgav,Gja1,Ifnar1,Ifi205,Tlr3,Prkce,Pcx,Tnfrsf14,Zmynd15,Nfkb1,Oas1g,Ifna1,Acp5,Trim34a,Il1b,Diaph2,Hmga2,Isg15,Mapkapk2,G3bp2,Il6,Saa3,Ciita,Mcm9,Cflar,Trem1,Prdm9,Slfn8,Bmp2,Samhd1,Hspa2,Ifih1,Tgtp1,Csf1,Gsr,Fzd5,Fcgr4,Tent5a,Myc,Ccl8,Kdm5b,Oas1b,Etv6,Ccl9,Tle3,Nr1h3,Rnf19b,Slfn9,Apobec3,Iigp1,Ifna2,Arid4a,Mecp2,Golga3,Herc6,Ccl7,Eif2ak2,Stat5a,Trim12a,Cxcl1,Ppp1r14b,Oas3,Ccl2,Batf,Slamf8,Gbp2,Fcgr1,Psmb9,Evl,Tlr9,Pf4,Nfkbia,Ddit4,Ifit3,Parp14,Jak2,Tlr6,Stat1,Nlrc4,Zbp1,Crkl,Ddx58,Adar,Ripk3,Trib1,Irf7,Tnfaip3,Cxcl3,Tarm1,Il12rb1,Tnfrsf1b,Clec4n,Ifi211,Plac8,Optn,Mndal,Nlrp3,Zc3hav1,Tmem229b,Cxcl10,Oas1a,Ptafr,Arg2,Klrk1,Raet1e,Lif,Serpina3f,Batf2,Ikbke,H2-Ab1,Peli1,Src,Hck,Stat3,Bcl2l11,Treml4,Smpdl3b,Gbp3,4932438A13Rik,Ifit3b,Fpr2,Lcn2,Stat2 |
| 6.259e-47 | -106.39 | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | 162 | 82 | 15632 | 1249 |
Gpr84,Bcl2a1d,Psma6,Dusp1,Tnf,Stat5a,Plekhf2,Otud1,Cd83,Sav1,Tnfaip3,Plk3,Rhoh,Csrnp1,Il1a,Icam1,Rnd1,Ddit4,Btg2,Slc7a5,Arl5b,Nfkbid,Inhba,Rapgef2,Cxcl2,Maff,Txn1,Plek,Gch1,Cd274,Ppp1r15a,Bcl2a1a,Cxcl1,Il15ra,Plaur,Il1b,Kdm6b,Dusp5,Zc3h12a,Ripk2,Ptgs2,Il12b,Map3k8,Il18,Edn1,Dusp2,Peli1,Il6,Nfkbia,Gadd45b,Bcl2a1b,Sod2,Jun,Ets2,Pim3,Slamf7,Nfkbiz,Egr1,Nlrp3,Tifa,Pdss1,Ccrl2,Usp12,Birc3,Dcun1d3,Ppp1r15b,Nfkb1,Il10,Rel,Gem,Cflar,Tnfaip2,Ccl4,Lrrc8c,Dram1,Pim2,Socs3,Dnajb4,Tnip3,Adrb2,Acsl1,Ier3 |
| 1.009e-46 | -105.91 | regulation of metabolic process | biological process | GO:0019222 | 6017 | 654 | 20694 | 1406 |
S100a8,Tnfsf4,Plaur,Acvr1,Hinfp,Nr4a1,Hdac1,Plau,Adam19,Adora2a,Aim2,Mov10,Ptger4,Atp2b4,Ets2,Cop1,Hivep3,Itgb8,Gadd45g,Irak3,Zfp36,Ctla2a,Radx,Nfkbid,Nod2,Serpine1,Lrp8,Tent2,Xrn1,Stap1,Tsku,Trim21,Ass1,Nfkbie,Tnfsf8,Nmi,Tlk2,Ptprj,Map4k4,Icosl,Dyrk2,Csf3,Gcnt2,Ifna4,Sesn3,Irgm2,Ifi208,Parp9,Tab2,Nos2,Gbp4,Spred1,Htra1,Pid1,Notch1,Rhoh,Tiparp,Irak2,Tlr2,Hmox1,Pim1,Tdrd7,Uaca,Klf8,Ccr1,Brwd3,Pml,Pim2,Ccnj,Eya4,Ago3,Prdm1,Pik3r5,Noct,Fzd1,Sod2,Ccl3,Ifi204,Oasl1,Syk,Pde3b,Ric1,Sh3bp4,Stat4,Ccl4,Cd74,C3,Fabp3,Tlr1,Oas2,Rnf31,Junb,Actb,Malt1,Ifnb1,Cdkn2d,Nod1,Jdp2,Rabgef1,Serpinb9,Ccl5,Trim14,Psip1,Larp1,Igf1r,Ankrd17,Map3k6,Vrk2,Fgr,Msr1,Fignl2,Tshz1,Wars,Phip,Nox1,Dusp2,Fam72a,Timeless,Cd38,Hspa1b,Fam129a,Tank,Cdyl,Bcl2a1d,Fos,Olr1,Ahrr,Ankib1,Cd80,Atm,Tent4a,Acsl1,Higd1a,Acsl5,Irf8,Trim13,Hp,Hhex,Pik3r6,Fam20c,Arf4,Klf3,Ier3,Slc7a11,Il4ra,Tnip1,Ncoa7,Lyn,Clcf1,Ahr,Ifi209,Helz2,Ptch1,Lmo4,Htr2b,Parp14,Ezr,Dio2,Maml2,Scyl2,Ddit4,Apaf1,Tlr9,Pf4,Slc9a1,Fcgr1,Spic,Cxcl1,Glipr2,Ccl7,Hopx,Ell2,Vegfc,Phactr4,Dcun1d3,Ppp2r1b,Mecp2,Iigp1,Cenpj,Ppp4r2,Rnf19b,Zeb1,Ccl9,Oas1b,Htr2a,Myc,Pde5a,Dcp1a,Plagl2,Spry2,Aff1,Klf2,Pde1b,Birc2,Dusp16,Csrnp1,Tfec,Lcn2,Tapbp,Hcls1,Sec24a,Tnks1bp1,Src,Stat3,Hck,Egr3,Lpar1,Batf2,Serpina3f,Pdgfb,Ak4,Klrk1,Ptafr,Mafg,Ranbp2,Mndal,Pou2f2,Optn,Apba1,Swap70,Trib1,Cycs,Cysltr2,Ripk3,Cd200,Maff,Adar,Crkl,Hat1,Spint2,Nlrc4,Prdx5,Stat1,Bcor,Fcgr2b,Gch1,Arid5a,Me1,Ift57,Zfp281,Met,Serp1,Myd88,Mafk,Irgm1,Magohb,Cacna1d,Kitl,Mdfic,Cx3cl1,Ubash3b,Nlrc5,Gfpt1,Kdr,Egr2,Rcan1,Cst7,Gadd45b,Spred3,Cgas,Il1rn,Txn1,Kdm6b,Mmp25,Dusp4,Gdf15,Bcl6,Ppp1r15a,Zhx2,Notch2,Rgcc,Egr1,Pmepa1,Fut8,Kmt5a,Eno1,Dnajb4,Rel,Ctsc,Prdm9,Cd34,Grk3,N4bp1,Plk2,Thbs1,Fbxo4,Prnp,Cflar,Sap30,Ppp6r1,Ciita,Jag1,Dusp8,Mamld1,Kdm4a,Il6,Itga5,Hif1a,Psme2,Ccnd2,Mapkapk2,Fubp1,Dram1,Pttg1,Hmga2,Ppp2r3a,Tal2,Mdm2,Psme1,Pdgfc,Relb,Pcx,Crlf3,Zmynd15,Psmd10,Nr4a3,Tnfsf14,Ccnd1,Hk2,Ikbkg,Casp3,Gja1,Itgav,Il10,Cx3cr1,Dach1,Map2k4,Irf2,Ppp1r15b,Phlpp1,Gk,Irf1,Klhl25,Tspo,Serpina3g,Plpp3,Bst1,Cmklr1,Cenpe,Hspa1a,Mmp14,Med13,Sav1,Dtx3l,Svbp,Irf4,Lnpep,Mtcp1,Hmga1,Fas,Rubcnl,Nsd3,Dnaja1,Prkar2b,Sema4c,Resf1,Serpinb2,Edn1,Jarid2,Casp1,Ifi203,Hap1,Ccne1,Il18rap,Ldlr,Smg7,Tut7,Nfkbil1,Trim26,Casp4,Hivep2,Znfx1,Stk40,Ripk2,Mul1,Hlx,Lrp4,Serpinb6b,Mvp,Rnf14,Nek6,Usp25,Ifna5,Mthfr,Traf2,Sele,Gfi1,Chmp4b,Serpinb9b,Ythdf1,Il18,Zc3h12a,Nfkbib,Foxp4,Marco,Atf3,Parp10,Sertad3,Taf4b,Ccl12,Caml,Rasgrp1,Il27,Prdx1,Mxd1,Ikzf1,Angpt1,Tcf4,Pcgf5,Jun,Fam162a,Daxx,Il1a,Tnf,Plk3,Mapkbp1,Cited2,Tpx2,Bambi,Pou3f1,Parp3,Gclc,Arid5b,Aida,Lipg,Max,Jmjd6,Irs2,Kat2b,Uchl1,Icam1,Rbl1,Cd40,Mycl,Mtdh,Dr1,Dync1h1,Igf2bp2,Adora2b,Nfxl1,Ppp2r2a,Marf1,Rap2c,Mier3,Spn,Rapgef2,Hsph1,Tax1bp1,Pik3cd,Plscr1,Dusp5,Ier2,Traf1,Oasl2,Ksr1,Mmd,Bcl9,Ifi213,Ptgs2,Klf6,Slpi,Nfil3,Cyfip1,Ddx4,Casz1,Lgals9,Ccl22,Arel1,Plcl2,Sirt1,Mmp9,Etv3,Osm,Cav1,Klf7,Spire1,Myadm,Pbx1,Trim30a,Sqstm1,Riox2,Acod1,Samd9l,Mllt6,Psmb8,Birc3,Sco1,Psmb9,Adrb2,Nfkbia,Dcp2,Arrdc4,Gtpbp2,Med21,Slamf8,Ppp1r14b,Oas3,Batf,Ccl2,Stat5a,Aebp2,Ppm1k,Map3k8,Plagl1,Eif2ak2,Slfn1,Pnpt1,Socs1,Socs3,Tnc,Arid4a,Ifna2,Plekhn1,Rbpms,Rnf34,Ptk2,Tle3,Nr1h3,Kdm5b,Fosb,Etv6,Ccl8,Ptpn2,Fzd5,Cebpd,Pdgfrb,Zc3h7a,Dnajb2,Ccng2,Gsap,Il15,Hcar2,Csf1,Nupr1,Ifrd1,S1pr2,Spen,Hspa2,Antxr1,Rhoq,Stat2,Fpr2,Odc1,Map2k1,Pdk3,Eif4g2,Nr3c1,Cox17,Bcl2l11,Peli1,Tnfsf15,Wdr43,Psma6,Lif,Vcan,Arg2,Flt1,Oas1a,Rgs14,Zc3hav1,Nlrp3,Scimp,Ifi211,Sp140,Plac8,Rnf139,Tnfrsf1b,Rictor,Tnfaip3,Irf7,Pgk1,Inhba,Dek,Hmgn3,Traf5,Ddx58,Tcea1,Sphk1,Cdyl2,Errfi1,Tlr6,Jak2,Timp1,Casp8,Pikfyve,Zfp513,Nampt,Rbbp8,Cdkn1a,Phf6,Ifi207,Sdc4,Etv5,Pla2g4a,Rnf19a,Nck1,Ifna6,Tnfsf10,Acvrl1,Rffl,Inpp5b,Cacybp,Dusp6,Mefv,Il12b,Agrn,Ifi214,Carhsp1,Bnip3,Tra2a,Samsn1,Ednrb,Tmem67,Brd2,Zbtb5,Bmp2,Cpeb4,Lhx2,Plek,Nmral1,Il2rg,Lox,Phgdh,Cnn2,Ptgs2os2,Mid1,Tnfrsf8,Nfkb2,Dusp1,Acvr1b,Perm1,Pmaip1,Polr2g,Tet2,Trib3,Isg15,Il1b,Mlkl,Ttc39b,Rfx5,Btg2,Acp5,Ifna1,Oas1g,Nfkb1,Tnfrsf14,Ppp2r5a,Cdk5r1,Prkce,Keap1,Tlr3,Plat,Ifi205,Ifnar1 |
| 1.203e-46 | -105.73 | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_UP | MSigDB lists | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_UP | 159 | 81 | 15632 | 1249 |
Cav1,Heatr6,Ppp1r15b,Nfkb1,Cd69,Irf1,Gpd2,Map2k4,Kpna3,Cpeb4,Mtdh,Dyrk2,Dusp16,Gfi1,Fam102b,Arf4,Tnfaip2,Gbp2b,Nlrc4,Gadd45b,Nfkbia,Gramd1a,Sbds,Nod2,Triobp,Ggct,Tor1aip2,Parp14,Peli1,Trim13,Nlrp3,Nr1h3,Atf3,Nck1,Foxp4,Hinfp,Slc25a25,Lcp2,Daam1,Ppp1r15a,Rrs1,Plek,Snx10,Pde4b,Vasp,Ext1,Wdr59,Reps1,Tnfsf15,Phlda1,Adora2b,Map3k8,Kdm6b,Xkr8,Naa25,Rcl1,Tcea1,Gca,Ikbke,Irak2,Ttc39c,Tank,Parp8,Tnf,Ehd1,Nfkbie,Lztfl1,Tlk2,Gsr,Rab11fip1,Pde1b,Rffl,Spata13,Marcksl1,Malt1,Plagl2,Relb,Crlf3,Nod1,Ccdc88b,Sla |
| 4.397e-46 | -104.44 | positive regulation of cellular process | biological process | GO:0048522 | 5346 | 600 | 20694 | 1406 |
Ikbkg,Itgav,Gja1,Casp3,Hk2,Nr4a3,Psmd10,Ccnd1,Tnfsf14,Relb,Crlf3,Pcx,Palld,Psme1,Pdgfc,Mdm2,Ppp2r3a,Hmga2,Fubp1,Mapkapk2,Hif1a,Itga5,Ccnd2,Psme2,Kdm4a,Il6,Jag1,Cflar,Vasp,Ciita,Fbxo4,Prnp,Cd34,Grk3,Cacnb3,Prdm9,Thbs1,Plk2,Ctsc,Sema4a,Ddhd1,Rel,Vcam1,Cxcl14,Ube2e2,Rgcc,Egr1,Calcrl,Notch2,Pdlim7,Ppp1r15a,Gdf15,Mmp25,Bcl6,Spred3,Gadd45b,Il1rn,Kdm6b,Txn1,Cgas,Mark2,Cst7,Kdr,Egr2,Nlrc5,Mdfic,Cx3cl1,Kitl,Cacna1d,Myd88,Serp1,Met,Irgm1,Ift57,Zfp281,Fcgr2b,Arid5a,Nlrc4,Stat1,Flrt3,Crkl,Ripk3,Cysltr2,Maff,Mpp7,Il12rb1,Cycs,Trib1,Swap70,Pou2f2,Abcc4,Optn,Ranbp2,Ptafr,Cxcl10,Mafg,Pdgfb,Klrk1,Piezo1,Ikbke,Lpar1,Stat3,Hck,Src,Egr3,H2-Ab1,Tnks1bp1,Gpr68,Sema3c,Sec24a,Hcls1,Tfec,Lcn2,Birc2,Triobp,Csrnp1,Ifih1,Klf2,Dock4,Aff1,Spry2,Plagl2,Dcp1a,Htr2a,Myc,Pde5a,Kmo,Ccl9,Zeb1,Rnf19b,Cenpj,Dcun1d3,Vegfc,Mecp2,Ppp2r1b,Ccl7,Hopx,Ell2,Ap3b1,Glipr2,Cxcl1,Spic,Tlr9,Pf4,Apaf1,Slc9a1,Fcgr1,Scyl2,Glrx,Ddit4,Ezr,Parp14,Maml2,Htr2b,Ptch1,Lmo4,Rims3,Helz2,Clcf1,Ahr,Sdc1,Il4ra,Ncoa7,Tnip1,Lyn,Sell,Arf4,Fam20c,Hhex,Pik3r6,Dhx58,Irf8,Axl,Acsl5,Gpsm2,Txnrd1,Hp,Trim13,Acsl1,Higd1a,Cd80,Atm,Ahrr,Ankib1,Fos,Fam129a,Tank,Hspa1b,Rab9,Whamm,Timeless,Cd38,Fam72a,Adgrl2,Wars,Phip,Nox1,Msr1,Larp1,Igf1r,Psip1,Fgr,Map3k6,Ankrd17,Ccl5,Jdp2,Ifnb1,Nod1,Junb,Gsdmd,Malt1,Rnf31,Tlr1,C3,Cd74,Fabp3,Ccl4,Syk,Stat4,Sh3bp4,Ifi204,Ccl3,Fzd1,Sod2,Noct,Prdm1,Pik3r5,Pim2,Ago3,Eya4,Pml,Ccr1,Uaca,Tlr2,Clec4d,Hmox1,Pim1,Clec4e,Itgal,Irak2,Cd300lf,Notch1,Pid1,Htra1,Cxcl9,Spred1,Scn1b,Wdr59,Smc5,Nos2,Tab2,Irgm2,Ifna4,Sesn3,Parp9,Gcnt2,Csf3,Icosl,Cdc42ep2,Dyrk2,Asns,Map4k4,Tnfsf8,Ass1,Ptprj,Nmi,Trim21,Stap1,Sp110,D16Ertd472e,Lrp8,Nod2,Pla2g7,Nfkbid,Flrt2,Carmil1,Serpine1,Zfp36,Gadd45g,Nectin2,Hivep3,Cop1,Mmp13,Ets2,Atp2b4,Ptger4,Mov10,Abcb1a,Adora2a,Aim2,Ehd1,Plau,Cdc42ep4,Hdac1,Tnfsf4,Nr4a1,Plaur,Acvr1,Hinfp,S100a8,Ifnar1,Nfkbiz,Tlr3,Cdk5r1,Prkce,4930453N24Rik,Nfkb1,Ppp2r5a,Tnfrsf14,Ifna1,Btg2,Mlkl,Isg15,Il1b,Polr2g,Tet2,Pmaip1,Trib3,Acvr1b,Dusp1,G3bp2,Nfkb2,Mid1,Tnfrsf8,Il2rg,Plek,Tnfsf9,Lhx2,Bmp2,Casp2,Tmem67,Sinhcaf,Tra2a,Cd14,Ednrb,Bnip3,Mefv,Agrn,Il12b,Traf3ip2,Ccdc88b,Sik3,Dusp6,Cacybp,H2-Aa,P2ry2,P2ry12,Tnfsf10,Gpr35,Acvrl1,Rnf19a,Ifna6,Nck1,Abcc1,Sdc4,Pla2g4a,Etv5,Nampt,Casp8,Cdkn1a,Timp1,Jak2,Tlr6,Tcea1,Sphk1,Zbp1,Traf5,Hmgn3,Ddx58,Rictor,Inhba,Pgk1,Irf7,Tnfaip3,Rnf139,Tnfrsf1b,Plac8,Clec4n,Scimp,Nlrp3,Zc3hav1,Rgs14,Akt3,Arg2,Flt1,Usp12,Lif,Wdr43,Gpc1,Tnfsf15,Bcl2l11,Phlda1,Peli1,Nr3c1,Cox17,Treml4,Map2k1,Eif4g2,Stat2,Odc1,Fpr2,Rhoq,S1pr2,Ifrd1,Antxr1,Hspa2,Spen,Hcar2,Il15,Csf1,Nupr1,Dnajb2,Gsap,Col18a1,Cebpd,Pdgfrb,Ptpn2,Fzd5,Ccl8,Nr1h3,Prag1,Fosb,Rac3,Etv6,Kdm5b,Gda,Ptk2,Ifna2,Socs3,Arid4a,Tnc,Plekhn1,Rbpms,Eef1e1,Pnpt1,Eif2ak2,Plagl1,Pdpn,Socs1,Stat5a,Map3k8,Batf,Ccl2,Arrdc4,Nfkbia,Adrb2,Evl,Med21,Mllt6,Birc3,Acod1,Itpr1,Sqstm1,Dbnl,Spire1,Pbx1,Myadm,Osm,Klf7,Cav1,Sirt1,Mmp9,Ccl22,Cd274,Cd83,Lgals9,Il15ra,Hilpda,Casz1,Klf6,Nfil3,Cyfip1,Ptgs2,Ifit2,Ksr1,Ier2,Syne2,Bcl9,Mmd,Plscr1,Spn,Pik3cd,Hsph1,Rapgef2,Rap2c,Cd86,F10,Adora2b,Dync1h1,Dr1,Cd40,Mtdh,Nlgn2,Mycl,Icam1,Hk1,Kat2b,Jmjd6,Irs2,Nqo1,Arid5b,Max,Fscn1,Gclc,Pou3f1,Cd180,Parp3,Stxbp1,Bambi,Cited2,Tpx2,Daxx,Il1a,Mapkbp1,Plk3,Tnf,Nsmaf,Rsad2,Fam162a,Tcf4,Jun,Pcgf5,Angpt1,Ikzf1,Il27,Acpp,Sertad3,Taf4b,Rasgrp1,Ccl12,Rras2,Atf3,Marco,Marcksl1,Frmd4a,Gpr18,Il18,Zc3h12a,Ythdf1,Scarf1,Sele,Gfi1,Trip10,Ifna5,Traf2,Nek6,Wdfy1,Tmod3,Rnf14,Lrp4,Tifa,Hlx,Mul1,Ripk2,Hivep2,Clec5a,Casp4,Ldlr,Casp1,Jarid2,Ccne1,Hap1,Resf1,Sema4c,Edn1,Dnaja1,Stau1,Fas,Nsd3,Pkp4,Hmga1,Mtcp1,Irf4,Dtx3l,Itga4,Ccr3,Med13,Rhoc,Sav1,Phldb1,Ddx60,Mmp14,Bst1,Kif3c,Cmklr1,Cenpe,Hspa1a,Lnpk,Plpp3,Fchsd2,Tspo,Irf1,Phlpp1,Map2k4,Ppp1r15b,Intu,Irf2,Rab21,Il10,Cx3cr1 |
| 5.182e-46 | -104.27 | GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN | 178 | 85 | 15632 | 1249 |
Wars,Parp12,Oas2,Ube2l6,Ifi208,H2-Aa,Nmi,Irf7,Fcgr4,Ifit1bl2,Ccr1,Gja1,Gch1,Sp110,Trafd1,Tfec,Arid5b,Tlr3,Herc6,Oas1g,Rsad2,Tapbp,Psma6,Dhx58,Sat1,Ifi44,Rab11fip1,Psmb9,Arhgef3,Ifi209,Ifi205,Oas3,Phf11b,Ifi213,Casp1,Myd88,Usp18,Ifih1,Isg15,Socs1,Arg2,Aim2,Psme1,Pla2g7,Mmd,Oas1a,Xaf1,Ifi203,Trim21,Isg20,Ifi211,Psme2,Plscr1,Ifit3,Lap3,Mndal,Vrk2,Rpgrip1l,Zcchc2,Rgs1,Ifi204,Phf11d,Ifit3b,Ifi35,Casp7,Kpna3,Stat1,Oasl1,Cd200,Dusp4,Irf4,Ptpn2,Ifit1bl1,Cenpe,Eif2ak2,Ifi207,Tap1,Phf11c,Phf11a,Pttg1,Ifi214,Rtp4,Fas,Ddx60,Lrp8 |
| 1.764e-45 | -103.05 | regulation of cellular protein metabolic process | biological process | GO:0032268 | 2573 | 362 | 20694 | 1406 |
Hhex,Pik3r6,Htr2b,Tnip1,Ncoa7,Lyn,Clcf1,Fam72a,Tank,Fam129a,Cdyl,Hspa1b,Dusp2,Cd80,Atm,Acsl1,Higd1a,Bcl2a1d,Ankib1,Ahrr,Actb,Malt1,C3,Cd74,Tlr1,Larp1,Igf1r,Vrk2,Fgr,Map3k6,Phip,Nox1,Wars,Jdp2,Cdkn2d,Nod1,Ifnb1,Ccl5,Rabgef1,Serpinb9,Pik3r5,Pml,Ccr1,Ago3,Ccnj,Syk,Ric1,Ccl4,Fzd1,Ccl3,Irak2,Pid1,Notch1,Uaca,Tlr2,Pim1,Map4k4,Gcnt2,Csf3,Ptprj,Tlk2,Nmi,Spred1,Irgm2,Ifna4,Parp9,Gbp4,Tab2,Gadd45g,Irak3,Zfp36,Ctla2a,Cop1,Xrn1,Trim21,Stap1,Nod2,Serpine1,Lrp8,Hdac1,S100a8,Nr4a1,Plaur,Acvr1,Atp2b4,Mov10,Ptger4,Adora2a,Aim2,Mdm2,Psme1,Pdgfc,Ppp2r3a,Ikbkg,Casp3,Psmd10,Ccnd1,Tnfsf14,N4bp1,Grk3,Thbs1,Plk2,Fbxo4,Prnp,Ctsc,Kdm4a,Il6,Itga5,Ccnd2,Psme2,Cflar,Ppp6r1,Dusp8,Gdf15,Mmp25,Dusp4,Bcl6,Ppp1r15a,Rcan1,Cst7,Spred3,Gadd45b,Il1rn,Txn1,Notch2,Rgcc,Egr1,Pmepa1,Ift57,Serp1,Myd88,Met,Fcgr2b,Arid5a,Ubash3b,Kdr,Kitl,Mdfic,Cx3cl1,Swap70,Crkl,Nlrc4,Spint2,Bcor,Stat1,Prdx5,Cycs,Trib1,Ripk3,Cysltr2,Adar,Tnks1bp1,Stat3,Src,Hcls1,Pdgfb,Ptafr,Lpar1,Serpina3f,Htr2a,Pde5a,Myc,Rnf19b,Ppp4r2,Ccl9,Dusp16,Birc2,Spry2,Tlr9,Apaf1,Fcgr1,Parp14,Ezr,Ddit4,Dcun1d3,Phactr4,Vegfc,Ppp2r1b,Mecp2,Glipr2,Ccl7,Ccl22,Plcl2,Sirt1,Mmp9,Lgals9,Sqstm1,Osm,Cav1,Myadm,Spn,Hsph1,Rapgef2,Dusp5,Ppp2r2a,Rap2c,Slpi,Cyfip1,Ksr1,Mmd,Ptgs2,Aida,Gclc,Cd40,Igf2bp2,Kat2b,Uchl1,Icam1,Prdx1,Angpt1,Atf3,Parp10,Rasgrp1,Caml,Ccl12,Tpx2,Fam162a,Jun,Il1a,Daxx,Mapkbp1,Plk3,Tnf,Ythdf1,Il18,Zc3h12a,Gfi1,Serpinb9b,Marco,Casp4,Casp1,Jarid2,Ccne1,Ldlr,Nek6,Usp25,Ifna5,Mthfr,Traf2,Stk40,Lrp4,Mul1,Ripk2,Serpinb6b,Mvp,Rnf14,Svbp,Dtx3l,Mmp14,Prkar2b,Dnaja1,Sema4c,Serpinb2,Edn1,Mtcp1,Fas,Nsd3,Phlpp1,Irf1,Klhl25,Il10,Cx3cr1,Map2k4,Ppp1r15b,Plpp3,Bst1,Hspa1a,Cenpe,Tspo,Serpina3g,Btg2,Mlkl,Ifna1,Polr2g,Pmaip1,Trib3,Isg15,Il1b,Tlr3,Plat,Ifnar1,Ppp2r5a,Tnfrsf14,Prkce,Cdk5r1,Cpeb4,Bmp2,Acvr1b,Dusp1,Lox,Mid1,Ednrb,Samsn1,Mefv,Il12b,Agrn,Tmem67,Rnf19a,Ifna6,Nck1,Tnfsf10,Acvrl1,Casp8,Cdkn1a,Sdc4,Dusp6,Rffl,Rnf139,Tnfrsf1b,Rgs14,Nlrp3,Scimp,Sphk1,Errfi1,Timp1,Jak2,Tlr6,Rictor,Inhba,Tnfaip3,Bcl2l11,Peli1,Stat2,Fpr2,Map2k1,Eif4g2,Lif,Vcan,Flt1,Tnfsf15,Ccl8,Pdgfrb,Fzd5,Ptpn2,Ptk2,Nr1h3,S1pr2,Antxr1,Hspa2,Dnajb2,Ccng2,Il15,Csf1,Nupr1,Gtpbp2,Nfkbia,Adrb2,Arrdc4,Ccl2,Ppp1r14b,Mllt6,Birc3,Sco1,Ifna2,Socs3,Rnf34,Rbpms,Plekhn1,Map3k8,Slfn1,Eif2ak2,Socs1 |
| 3.760e-45 | -102.29 | GO_REGULATION_OF_IMMUNE_RESPONSE | MSigDB lists | GO_REGULATION_OF_IMMUNE_RESPONSE | 747 | 182 | 15632 | 1249 |
Tnip1,Actb,Siglece,Clcf1,Cd300e,Gfi1,Trem1,Stat1,Pik3cd,Ifi203,Rasgrp1,Sirt1,Birc3,Rabgef1,Psmb8,Itgal,Adar,Fcgr1,Angpt1,Tap1,Tnfrsf14,Abr,Nlrp3,Prkce,Irf4,Nod2,Nlrc5,Ezr,Psmd10,Fos,Trafd1,H2-Ab1,Serpinb9,Ptafr,Ifna6,Samsn1,Relb,Myo10,Hck,Itga4,Hlx,Malt1,Trim12c,Socs1,Stat2,Ddx58,Cd180,Psma6,Src,Birc2,Cd40,Tank,Hspa1a,C3,Tlr9,Map2k4,Tnip3,Cacnb3,Ifi204,Ifi211,Cav1,Clec4e,Cd80,Slamf7,Cd34,Il27,Zc3hav1,Nr1h3,Parp9,Ifna5,Ptpn2,Nlrc4,Ikbke,Il1b,Hmox1,Psmb6,Ripk2,Nr4a3,Adora2b,H2-Aa,H2-Eb1,Irf7,Fzd5,Myd88,Irak3,Ifna2,Cd38,Aim2,Ifih1,Rnf135,Psmb10,Tab2,Ifi209,Ankrd17,Cd300lf,Socs3,Cd200,Tnfsf4,Tlr2,Irf1,Plscr1,Smpdl3b,Rnf31,Clec4n,C1rl,Marco,Il10,Ifna1,Samhd1,Tlr6,Mapkapk2,Il4ra,Prnp,Il6,Peli1,H2-Q4,Nfkbia,Jun,Cyfip1,Plcl2,Cd55,Ptprj,Clec4d,Il12b,Ifi208,Tlr1,Nmi,Tyk2,Pik3r6,Cd86,Nod1,Ripk3,Nfkbil1,Psme1,H2-Q7,Fgr,Sell,Icam1,Dennd1b,C1ra,Ifnar1,Ifi213,Ifi205,Psmb9,Jak2,Ptk2,Lyn,Psme2,Ikbkg,Nfkb1,Mndal,Casp8,Il15,Ifi207,Nck1,Ddx60,Ifi214,Mul1,Stap1,Fcgr2b,Ifnb1,Syk,Spn,Irak2,Vcam1,Tlr3,Wdfy1,Il12rb1,Ccl5,Pde4b,Lcp2,Cd14,Tnfaip3,Cd74,Usp18,Dhx58,Rsad2,Treml2,Tnf,Bcl6,Traf2,H2-Q6 |
| 5.616e-45 | -101.89 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_DN | 149 | 77 | 15632 | 1249 |
Pml,Csrnp1,Dtx3l,Ifih1,Isg15,Traf1,Usp18,Stat2,Ddx58,Myo10,Src,Phf11b,Ifit2,Oas3,Homer1,Ifi44,Batf2,Rab11fip1,Rsad2,Dhx58,Tlk2,Errfi1,Dusp5,Herc6,Kdm6b,Nr4a3,Cxcl10,Usp42,4930453N24Rik,Nfkb2,Irak2,Tnfsf10,Snapc1,Gtpbp2,Cmpk2,Epsti1,Gch1,Myadm,Ifit1bl2,Nampt,Slc31a2,Irf7,Ppm1k,Cd274,Arl5b,Ddit4,Oas2,Ddx60,Rtp4,Adar,Cd80,Pnpt1,Phf11a,Zbp1,Tap1,Phf11c,Ifit1bl1,Nlrc5,Gadd45b,Znfx1,Peli1,Parp14,Parp9,Samd9l,Oasl1,Ifi35,Ifit3b,Irf1,Phf11d,Ifit3,Plscr1,Isg20,Trim21,Xaf1,Dcp1a,Trim56,Rictor |
| 5.761e-45 | -101.87 | GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN | 178 | 84 | 15632 | 1249 |
Bcl2a1d,Cers6,Stat5a,Tnf,Psmb9,Arid5a,Batf,Cd83,Cd38,Gbp2,Itga4,Rhoh,Stat2,Icam1,Jmjd6,Traf1,Socs1,Trim26,Nrp2,Ube2l6,Pdgfb,Wars,Oas2,Plek,Slc31a2,Junb,Txn1,Ccl5,Tap2,Lcp2,Irf7,Bcl2a1a,Serpinb2,Il15ra,Sp110,Trafd1,Il1b,Ptger4,Rnf19b,Dnaja2,Dusp5,Ak4,Pim1,Ptafr,Cxcl10,Irf4,Il6,Tra2a,Gadd45g,Rab32,Gadd45b,Hivep2,Bcl2a1b,Ptpn2,Jun,Il15,Ciita,Sdc4,Fcgr1,Cdc42ep2,Tap1,P2ry14,Isg20,St3gal5,Psme2,Zfp36,Ccrl2,Stat4,Cd69,Psmb8,Irf8,Casp4,Gem,Jak2,Rbms1,Tnfaip2,Cdkn1a,Ifi35,Socs3,Pim2,Irf1,Acvr1b,Trib1,Rcn1 |
| 8.252e-45 | -101.51 | GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 779 | 186 | 15632 | 1249 |
Rasgrp1,Ifi203,Sirt1,Jag1,Rabgef1,Psmb8,Birc3,Tnip1,Clcf1,Actb,Pik3cd,Prkce,Cxcl14,Nod2,Nlrc5,Psmd10,Fos,Fcgr1,Tap1,Tnfrsf14,Nlrp3,Csf3,Thbs1,Cmklr1,Pf4,Vegfc,Ptger4,H2-Ab1,Cxcl10,Ptafr,Pnp2,Psma6,Src,Hsph1,Hspa1a,Tank,Cd40,Birc2,Cd83,Myo10,Hck,Relb,Lif,Malt1,Itga4,Hlx,Trim12c,Isg15,Hif1a,Cd180,Ddx58,Ifi211,Rictor,Nos2,Cav1,C3,Egr3,Tlr9,Tnip3,Cacnb3,Ifi204,Mmp14,Nlrc4,Cd80,Clec4e,Zc3hav1,Cx3cl1,Nr1h3,H2-Aa,Icosl,Bst1,Ccr1,H2-Eb1,Irf7,Serpine1,Cd274,Fzd5,Tap2,Ikbke,Kitl,Cxcl1,Il1b,Ripk2,Psmb6,Hmox1,Nr4a3,Map3k8,Il18,Adora2b,Ifi209,Ankrd17,Ccdc88b,Myd88,Irak3,Cd38,Prdm1,Aim2,Psmb10,Ifih1,Tab2,Plscr1,Pla2g7,Rnf31,Clec4n,C1rl,Marco,Tnfsf14,Hcls1,Ebi3,Tnfsf4,Tlr2,Acvr1b,Il6,Peli1,Abcb1a,Ccl12,Nfkbia,H2-Q4,Jun,Cyfip1,Tlr6,Mapkapk2,Il4ra,Tlr1,Ifi208,Pik3r6,Cd86,Hcar2,Ptprj,Cd55,Il12b,Clec4d,Dennd1b,C1ra,Ifi213,Axl,Ifi205,Swap70,Psmb9,Nod1,H2-Q7,Psme1,Fgr,Icam1,Psme2,Csf1,Nfkb1,Ikbkg,Casp8,Mndal,Ccl4,Cdkn1a,Ptk2,Lyn,Trib1,Stap1,Ifnb1,Ap3b1,Syk,Spn,Il15,Ifi207,Ddx60,Nck1,Irs2,Ifi214,Wdfy1,Cxcl2,Il12rb1,Inhba,Ccl5,Pde4b,Lcp2,Irak2,Vcam1,Tlr3,Gpr68,Rsad2,Dhx58,Tnf,Bcl6,H2-Q6,Traf2,Cd14,Tnfaip3,Cd74 |
| 1.477e-44 | -100.92 | positive regulation of response to stimulus | biological process | GO:0048584 | 2114 | 316 | 20694 | 1406 |
Flt1,Usp12,Cxcl10,Ptafr,Arg2,Klrk1,Pdgfb,Raet1e,Lif,Ikbke,Lpar1,Tnfsf15,Peli1,H2-Ab1,Src,Bcl2l11,Stat3,Treml4,Gpr68,Nr3c1,Trim12c,Hcls1,Map2k1,Fpr2,Jak2,Lcp2,Tlr6,Nlrc4,Sphk1,Zbp1,Crkl,Ddx58,Cysltr2,H2-Q4,Ripk3,Traf5,Irf7,Tnfaip3,Inhba,Tarm1,Rictor,Il12rb1,Swap70,Ifi211,Clec4n,Optn,Mndal,Nlrp3,Scimp,Akt3,Zc3hav1,Rbpms,Cenpj,Ppp2r1b,Eef1e1,Vegfc,Hopx,Pdpn,Eif2ak2,Ccl7,Map3k8,Cxcl1,Stat5a,Glipr2,Ccl2,Fcgr1,Slc9a1,Apaf1,Adrb2,Nfkbia,Tlr9,Glrx,Parp14,H2-Q6,Ifih1,Dennd1b,Csf1,Nupr1,Il15,Spry2,Fzd5,Ptpn2,Pdgfrb,Plagl2,Myc,Pde5a,Ccl8,Htr2a,Ccl9,Prag1,Nr1h3,Ptk2,Hif1a,Acvr1b,Il6,Mid1,Jag1,Cflar,Plek,Thbs1,Cacnb3,Bmp2,Ctsc,Casp2,Gja1,H2-T10,Ikbkg,Ifi205,Nfkbiz,Tlr3,Tnfsf14,Prkce,Nr4a3,Tnfrsf14,Crlf3,Nfkb1,Pdgfc,Mlkl,Il1b,Ppp2r3a,Pmaip1,Mapkapk2,Kdr,Sik3,Nlrc5,Cx3cl1,Mdfic,Cacna1d,P2ry12,Kitl,Acvrl1,Gpr35,Irgm1,Tnfsf10,Met,Myd88,Nck1,Arid5a,Pla2g4a,Fcgr2b,Casp8,Cxcl14,Tmem67,Tnip3,Rgcc,Notch2,Ppp1r15a,Cd14,Bnip3,Gdf15,Ifi214,Cgas,Traf3ip2,Il1rn,Il12b,Spred3,Gadd45b,Cd55,Traf2,Spred1,Tab2,Wdr59,Wdfy1,Parp9,Ripk2,Mul1,Hlx,Ifi208,Tifa,Irgm2,Icosl,Gcnt2,Csf3,Casp4,Map4k4,Ldlr,Ptprj,Il18rap,Hap1,Ifi203,Pvr,Casp1,Marco,Gpr18,Clec4e,Tlr2,Themis2,H2-T22,Itgal,Zc3h12a,Il18,Irak2,Cd300lf,Scarf1,Notch1,Gfi1,Cmklr1,Plpp3,Abcb1a,Ptger4,Aim2,Adora2a,Irf1,Hdac1,Phlpp1,Intu,Plaur,Acvr1,Map2k4,Tnfsf4,S100a8,Cx3cr1,H60b,Il10,Stap1,Edn1,Sema4c,Tap2,H2-Q7,Fas,Serpine1,Nfkbid,Nod2,Pla2g7,Irak3,Dtx3l,Gadd45g,Enpp4,Nectin2,C1ra,Ddx60,Cyfip1,Atm,Ptgs2,Bcl2a1d,Ksr1,H2-M2,Plscr1,Rapgef2,Timeless,Cd38,Spn,Cd86,Adora2b,F10,Acod1,Htr2b,Ifi209,C1rl,Spire1,Clcf1,Sell,Cav1,Lyn,Osm,Tnip1,Il4ra,Mmp9,Sirt1,H2-T24,Ccl22,Pik3r6,Dhx58,Hhex,Cd274,Trim13,Lgals9,Axl,Bambi,Ccl4,Stxbp1,Syk,Cited2,Tnf,Mapkbp1,Ccl3,Il1a,Daxx,Ifi204,Jun,Fam162a,Rsad2,Angpt1,Pik3r5,Ccl12,Eya4,Rasgrp1,Ago3,Pim2,Acpp,Atf3,Ccr1,Pml,Nox1,Phip,Ankrd17,Map3k6,Nlgn2,Fgr,Mtdh,Cd40,Igf1r,Ccl5,Hk1,Icam1,Ifnb1,Nod1,Malt1,Fpr1,Rnf31,Pde4b,Tlr1,Parp3,Cd180,Cd74,C3 |
| 2.761e-44 | -100.30 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_DN | 168 | 81 | 15632 | 1249 |
Ddit4,Stoml1,Oas2,Stx11,Parp12,Hk2,Slc31a2,Nampt,Ifit1bl2,Rgl1,Myadm,Gch1,Cd274,Cnp,Irf7,Gtpbp2,Tnfsf10,Kitl,Epsti1,Glrx,Cmpk2,Sp110,Herc6,4930453N24Rik,Usp42,Cxcl10,Nr4a3,Batf2,Rab9,Ifi44,Errfi1,Tlk2,Rsad2,Dhx58,Phf11b,Ifit2,Oas3,Myd88,Ncoa7,Csrnp1,Pml,Ddx58,Usp18,Stat2,Trim12c,Isg15,Ifih1,Dtx3l,Isg20,Trim14,Plscr1,St3gal5,Trim56,Dcp1a,Xaf1,Abtb2,Ifit3,Oasl1,Stat1,Dnajb4,Phf11d,Irf1,Ifit3b,Parp14,Stard5,Samd9l,Phactr4,Parp9,Nlrc5,Morc3,Ifit1bl1,Znfx1,Il15,Zbp1,Adar,Phf11a,Pnpt1,Phf11c,Tap1,Ddx60,Rtp4 |
| 3.028e-44 | -100.21 | GO_INNATE_IMMUNE_RESPONSE | MSigDB lists | GO_INNATE_IMMUNE_RESPONSE | 498 | 143 | 15632 | 1249 |
Irf1,Pik3cd,Mefv,Tlr2,Ifi35,Stat1,Trem1,Cd300e,Ifit3,Irf8,Marco,Lcn2,Casp4,C1rl,Clec4n,Psmb8,Oas1a,Ifi203,Trim13,Ccl22,Nlrp3,Tlr6,Egr1,Samhd1,Prdx1,Ifna1,Ciita,Adar,Fcgr1,Zbp1,Nlrc5,Ifit1bl1,H2-Q4,Ccl12,Nod2,Irgm2,Edn1,Irf4,Ccl2,Clec5a,Ptafr,Il12b,Clec4d,Cd55,H2-Ab1,Oas1g,Cd86,Ifit1bl2,Gch1,Tyk2,Oas2,Ifi208,Tlr1,Ifna6,Stat2,Cd180,Ddx58,Icam1,Isg15,Trim12c,Fgr,H2-Q7,Malt1,Irf2,Pml,Relb,Gbp2,Hck,Nod1,Ifi205,Src,Axl,Ifi213,Apobec3,Ifnar1,C1ra,Gbp4,Ifi204,Lyn,Ifit3b,Tlr9,Ptk2,Oasl1,C3,Jak2,Ccl4,Rel,Nos2,Mndal,S100a8,Nfkb1,Ikbkg,Trim56,Xaf1,Trim14,Isg20,Trim21,Ifi211,Csf1,Slpi,Ifi214,Cx3cl1,Ddx60,Ifi207,Zc3hav1,Il27,Clec4e,Slamf7,Nlrc4,Gsdmd,Eif2ak2,Ass1,Ppp1r14b,Syk,Mid1,Ifnb1,Ifna5,Tlr3,Ripk2,Vcam1,Ikbke,Nfkb2,Irf7,H2-Eb1,Ccl5,Il12rb1,Trim26,H2-Aa,Rnf135,Ifih1,Aim2,Ifna2,Ccl3,Myd88,Cd14,H2-Q6,Ankrd17,Ifi209,Oas3,Ifit2,Dhx58,Rsad2,Gbp9 |
| 3.029e-44 | -100.21 | regulation of macromolecule metabolic process | biological process | GO:0060255 | 5565 | 612 | 20694 | 1406 |
Timeless,Cd38,Fam72a,Fam129a,Tank,Cdyl,Hspa1b,Dusp2,Cd80,Tent4a,Atm,Acsl1,Higd1a,Fos,Olr1,Bcl2a1d,Ankib1,Ahrr,Arf4,Ier3,Klf3,Irf8,Trim13,Hhex,Pik3r6,Helz2,Ptch1,Htr2b,Lmo4,Tnip1,Ncoa7,Lyn,Clcf1,Ifi209,Ahr,Prdm1,Pik3r5,Noct,Pml,Brwd3,Ccr1,Pim2,Ago3,Ccnj,Eya4,Syk,Stat4,Ric1,Ccl4,Fzd1,Sod2,Ifi204,Ccl3,Oasl1,Oas2,Rnf31,Junb,Malt1,Actb,C3,Cd74,Tlr1,Igf1r,Larp1,Psip1,Vrk2,Fgr,Map3k6,Ankrd17,Phip,Nox1,Wars,Msr1,Fignl2,Tshz1,Jdp2,Cdkn2d,Ifnb1,Nod1,Ccl5,Trim14,Serpinb9,Rabgef1,Map4k4,Csf3,Gcnt2,Icosl,Dyrk2,Tnfsf8,Nfkbie,Ptprj,Tlk2,Nmi,Spred1,Htra1,Irgm2,Ifna4,Parp9,Ifi208,Gbp4,Tab2,Nos2,Irak2,Tiparp,Pid1,Notch1,Tdrd7,Uaca,Klf8,Tlr2,Hmox1,Pim1,Hdac1,Adam19,S100a8,Tnfsf4,Nr4a1,Hinfp,Plaur,Acvr1,Atp2b4,Ptger4,Mov10,Ets2,Adora2a,Aim2,Gadd45g,Irak3,Zfp36,Ctla2a,Cop1,Hivep3,Itgb8,Tent2,Xrn1,Tsku,Trim21,Stap1,Nod2,Radx,Nfkbid,Serpine1,Lrp8,Grk3,Cd34,N4bp1,Prdm9,Thbs1,Plk2,Fbxo4,Prnp,Rel,Ctsc,Kdm4a,Il6,Itga5,Hif1a,Ccnd2,Psme2,Cflar,Sap30,Ciita,Ppp6r1,Jag1,Mamld1,Dusp8,Mdm2,Psme1,Pdgfc,Fubp1,Mapkapk2,Pttg1,Ppp2r3a,Hmga2,Tal2,Ikbkg,Gja1,Itgav,Casp3,Relb,Zmynd15,Pcx,Crlf3,Nr4a3,Psmd10,Ccnd1,Tnfsf14,Ift57,Zfp281,Myd88,Serp1,Met,Mafk,Fcgr2b,Arid5a,Ubash3b,Nlrc5,Gfpt1,Egr2,Kdr,Magohb,Kitl,Cacna1d,Mdfic,Cx3cl1,Gdf15,Dusp4,Mmp25,Bcl6,Ppp1r15a,Rcan1,Cst7,Gadd45b,Spred3,Cgas,Il1rn,Kdm6b,Txn1,Fut8,Kmt5a,Eno1,Dnajb4,Notch2,Zhx2,Rgcc,Pmepa1,Egr1,Tnks1bp1,Hck,Stat3,Src,Egr3,Tfec,Lcn2,Sec24a,Tapbp,Hcls1,Pdgfb,Ptafr,Mafg,Lpar1,Serpina3f,Batf2,Pou2f2,Optn,Apba1,Swap70,Mndal,Crkl,Hat1,Nlrc4,Spint2,Bcor,Stat1,Prdx5,Cycs,Trib1,Ripk3,Cysltr2,Maff,Adar,Cd200,Apaf1,Tlr9,Pf4,Fcgr1,Slc9a1,Spic,Parp14,Ezr,Maml2,Scyl2,Ddit4,Dcun1d3,Phactr4,Vegfc,Mecp2,Ppp2r1b,Cenpj,Glipr2,Ccl7,Hopx,Ell2,Htr2a,Pde5a,Myc,Dcp1a,Plagl2,Rnf19b,Ppp4r2,Ccl9,Oas1b,Zeb1,Klf2,Dusp16,Birc2,Csrnp1,Spry2,Aff1,Spn,Mier3,Pik3cd,Tax1bp1,Rapgef2,Hsph1,Dusp5,Plscr1,Nfxl1,Ppp2r2a,Rap2c,Marf1,Slpi,Klf6,Ddx4,Nfil3,Cyfip1,Casz1,Oasl2,Ksr1,Ier2,Traf1,Bcl9,Mmd,Ifi213,Ptgs2,Ccl22,Arel1,Plcl2,Sirt1,Mmp9,Etv3,Lgals9,Sqstm1,Riox2,Acod1,Samd9l,Osm,Klf7,Cav1,Spire1,Trim30a,Myadm,Pbx1,Il27,Prdx1,Mxd1,Angpt1,Ikzf1,Atf3,Taf4b,Parp10,Sertad3,Rasgrp1,Caml,Ccl12,Cited2,Tpx2,Bambi,Fam162a,Pcgf5,Jun,Tcf4,Daxx,Il1a,Mapkbp1,Tnf,Plk3,Arid5b,Aida,Max,Lipg,Pou3f1,Parp3,Gclc,Cd40,Rbl1,Mtdh,Mycl,Dr1,Igf2bp2,Irs2,Kat2b,Jmjd6,Uchl1,Icam1,Nfkbil1,Trim26,Tut7,Casp4,Hivep2,Casp1,Jarid2,Ccne1,Hap1,Ifi203,Il18rap,Ldlr,Smg7,Nek6,Usp25,Ifna5,Mthfr,Traf2,Znfx1,Stk40,Lrp4,Mul1,Ripk2,Hlx,Serpinb6b,Mvp,Rnf14,Ythdf1,Il18,Zc3h12a,Gfi1,Sele,Serpinb9b,Nfkbib,Marco,Foxp4,Phlpp1,Irf1,Klhl25,Il10,Cx3cr1,Dach1,Map2k4,Ppp1r15b,Irf2,Plpp3,Bst1,Cenpe,Cmklr1,Hspa1a,Tspo,Serpina3g,Svbp,Dtx3l,Irf4,Mmp14,Med13,Sav1,Prkar2b,Dnaja1,Resf1,Sema4c,Serpinb2,Edn1,Hmga1,Mtcp1,Fas,Rubcnl,Nsd3,Lhx2,Cpeb4,Nmral1,Zbtb5,Bmp2,Nfkb2,Acvr1b,Dusp1,Perm1,Il2rg,Phgdh,Lox,Mid1,Tnfrsf8,Ptgs2os2,Cnn2,Btg2,Mlkl,Rfx5,Ifna1,Tet2,Polr2g,Pmaip1,Trib3,Isg15,Il1b,Tlr3,Ifi205,Plat,Ifnar1,Oas1g,Nfkb1,Ppp2r5a,Tnfrsf14,Keap1,Prkce,Cdk5r1,Rnf19a,Ifna6,Nck1,Tnfsf10,Acvrl1,Rbbp8,Casp8,Zfp513,Nampt,Ifi207,Phf6,Cdkn1a,Sdc4,Etv5,Cacybp,Dusp6,Inpp5b,Rffl,Carhsp1,Ifi214,Tra2a,Ednrb,Samsn1,Mefv,Agrn,Il12b,Brd2,Tmem67,Nr3c1,Bcl2l11,Peli1,Stat2,Odc1,Fpr2,Map2k1,Eif4g2,Lif,Vcan,Oas1a,Flt1,Tnfsf15,Psma6,Wdr43,Plac8,Sp140,Ifi211,Rnf139,Tnfrsf1b,Zc3hav1,Rgs14,Nlrp3,Scimp,Tcea1,Cdyl2,Sphk1,Errfi1,Timp1,Tlr6,Jak2,Rictor,Inhba,Tnfaip3,Irf7,Hmgn3,Traf5,Dek,Ddx58,Adrb2,Dcp2,Arrdc4,Nfkbia,Gtpbp2,Psmb9,Med21,Batf,Oas3,Ccl2,Ppp1r14b,Mllt6,Psmb8,Birc3,Sco1,Socs3,Arid4a,Ifna2,Tnc,Rnf34,Plekhn1,Rbpms,Stat5a,Map3k8,Aebp2,Pnpt1,Plagl1,Slfn1,Eif2ak2,Socs1,Ccl8,Cebpd,Pdgfrb,Ptpn2,Fzd5,Ptk2,Nr1h3,Tle3,Kdm5b,Fosb,Etv6,S1pr2,Ifrd1,Spen,Antxr1,Hspa2,Rhoq,Zc3h7a,Dnajb2,Gsap,Ccng2,Il15,Nupr1,Csf1 |
| 4.247e-44 | -99.87 | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_DN | MSigDB lists | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_DN | 173 | 82 | 15632 | 1249 |
Mvp,Gbp2,Cd38,Myd88,Psmb10,Isg15,Ifih1,Sell,Socs1,Icam1,Pml,Aim2,Psme1,Rsad2,Fgl2,Ifi44,Cd40,Oas3,Rhbdf2,Arid5a,Psmb9,N4bp1,Cst7,Sp140,Phf11b,Sp110,Trafd1,Glrx,Il15ra,Tnfsf10,Tapbpl,Cxcl10,Pim1,Rnf19b,H2-Ab1,Parp12,Wars,Rapgef2,Nmi,Ube2l6,Irf7,Tap2,Gch1,Pde4b,Snx10,Plek,Phf11c,Tap1,Phf11a,Adar,Slamf7,Il15,Ciita,P2ry14,Rtp4,Fas,Ddx60,Scarf1,Nod2,Stap1,Pla2g4a,Rnf114,Vrk2,Tnfaip2,Jak2,Dr1,Lyn,Ifit3b,Phf11d,Irf1,Rcn1,Stat1,Ifi35,Tdrd7,Psme2,St3gal5,Isg20,Pstpip2,Lap3,C1rl,Ifit3,Psmb8 |
| 5.177e-44 | -99.67 | GSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN | MSigDB lists | GSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN | 182 | 84 | 15632 | 1249 |
Trib1,Map2k4,Rab20,Slc25a22,Ifit3b,Ifi35,Ppa1,Dusp16,Nfil3,Cdkn1a,Ccl4,Ifit3,Il10,Gem,Ogfr,Hdc,Hivep3,Rhou,Tdrd7,Plscr1,Fpr2,Rtp4,Spred1,Slc25a25,Sdc4,Il15,Adar,Zbp1,Znfx1,Ezr,Spsb1,Sod2,Bcl2l11,Slc7a11,Ccl12,Rin2,Edn1,Ccl2,Ptgs2,Adora2b,Map3k8,Larp1,Il1rn,Clic4,Tnfsf10,Plat,Irf7,Ccl5,Csf3,Mmp13,Maff,Hk2,Oas2,Ext1,Noc4l,Usp18,Upp1,Il1a,Hif1a,Ifih1,Socs1,Marcksl1,Pml,Nupr1,Lif,Cd164,Daxx,Gbp2,Hck,Cd14,Lipg,Timp1,Tpst1,Ehd1,Stat5a,Klf6,Ifit2,Txnrd1,Fgl2,Glipr2,Tapbp,Slc15a3,Batf2,Cish |
| 8.285e-44 | -99.20 | response to organic substance | biological process | GO:0010033 | 2767 | 376 | 20694 | 1406 |
Fos,Abr,Acsl1,Ifit1,Gbp2b,Atm,Cd80,Stoml1,Tank,Hspa1b,Cd38,Timeless,Ifi209,Ahr,Lyn,Sell,Il4ra,Slc7a11,Htr2b,Ptch1,Usp18,Trim13,Hp,Axl,Irf8,Ifi204,Ccl3,Ccl4,Sh3bp4,Stat4,Syk,Pde3b,Zyx,Pml,Ccr1,Rab20,Noct,Col4a2,Ccl5,Cxcl2,Nod1,Cdkn2d,Srm,Ifnb1,Phip,F830016B08Rik,Igf1r,Larp1,Tlr1,Cd74,Malt1,Actb,Junb,Pde4b,Oas2,Gbp4,Tab2,Nos2,Ifi208,Irgm2,Sesn3,Ifna4,Cxcl9,Nmi,Stx11,Ass1,Cmpk2,Xcr1,Csf3,Gcnt2,Cdc42ep2,Pim1,Tlr2,Flnb,Gm4841,Notch1,Pid1,Tiparp,Irak2,Cd300lf,Aim2,Adora2a,Shfl,Ehd1,Egln3,Mmp13,Atp2b4,Ptger4,Nr4a1,Acvr1,Tnfsf4,Cdc42ep4,Hdac1,Igtp,H2-Q7,Tap2,Serpine1,Nod2,Flrt2,Trim21,Stap1,Homer1,Zfp36,Irak3,Jag1,Ciita,Cflar,Il6,9930111J21Rik1,Ctsc,Rel,Prnp,Thbs1,Ccnd1,Nr4a3,Relb,Itgav,Casp3,Hk2,Mapkapk2,Pdgfc,Mdm2,Cx3cl1,Kdr,Egr2,Gbp9,Gch1,Arid5a,Fcgr2b,Irgm1,Myd88,Serp1,Me1,Rab10,Egr1,Calcrl,Hmgcs1,Eno1,Vcam1,Fut8,Il1rn,Cgas,Ppp1r15a,Gdf15,Ikbke,Serpina3f,Lrch1,Lpar1,Cxcl10,Xaf1,Ptafr,Ebi3,Ero1l,Pdgfb,Klrk1,Gbp3,Hcls1,Egr3,H2-Ab1,Stat3,Src,Adar,Trib1,Il12rb1,Cxcl3,Stat1,Flrt3,Crkl,Mndal,Optn,Ccl7,Cxcl1,Iigp1,Mecp2,Vegfc,Ddit4,Glrx,Stip1,Ezr,Slc9a1,Gbp2,Apaf1,Tlr9,Pf4,Spry2,Csf3r,Ccrl2,Birc2,Pde1b,Tgtp1,Ifih1,Ccl9,Zeb1,Fcgr4,Dcp1a,Myc,Htr2a,Ptgs2,Ifi213,Ifit2,Ier2,H2-Eb1,Nfil3,Cyfip1,Slpi,Klf6,Cd86,Ppp2r2a,Plscr1,Hsph1,Rapgef2,Cxcl11,Cav1,Osm,Acod1,Itpr1,Cd83,Cd274,Lgals9,Il15ra,Etv3,Sirt1,Mmp9,Ccl22,Tnf,Il1a,Daxx,Jun,Stxbp1,Bambi,Cited2,Ccl12,Asah2,Atf3,Icam1,Slc16a1,Irs2,Kat2b,Mtdh,Gbp8,Pfkl,Il13ra1,Gclc,Cd180,Arid5b,Ripk2,Mul1,Traf2,Ifna5,Ldlr,Il18rap,Idi1,Hap1,Ifi203,Casp1,Jarid2,Casp4,Nfkbil1,Nfkbib,Sele,Gfi1,Zc3h12a,Il18,Serpina3g,Gbp7,Hspa1a,Cx3cr1,Il10,Irf1,Gk,Esd,Fas,Socs7,Dnaja1,Tgtp2,Ptgir,Ccr3,Casp7,Mmp14,Itga4,Gclm,Saa3,Lox,Il2rg,Acvr1b,Dusp1,Bmp2,Nmral1,Nrp2,Cpeb4,Keap1,Prkce,Cdk5r1,Nfkb1,Ifnar1,Ifi205,Tlr3,Acp2,Il1b,Isg15,Trib3,Ifna1,Acp5,P2ry12,Gm5431,Cacybp,H2-Aa,Pla2g4a,Ifi207,Trim56,Casp8,Gpr35,Acvrl1,Agtrap,Ifna6,Tnip3,Stxbp3,Tmem67,Il12b,Mefv,P2ry13,Ednrb,Cd14,Ifitm1,Ifi214,Flt1,Pdk3,Map2k1,Fpr2,Stat2,Snx10,Peli1,Nr3c1,Ddx58,Inhba,Tnfaip3,Irf7,Timp1,Tlr6,Jak2,Sphk1,Nlrp3,Zc3hav1,Gramd1a,Akt3,Tnfrsf1b,Rnf139,Ifi211,Ifi47,Socs1,Pnpt1,Eif2ak2,Stat5a,Ifna2,Socs3,Gm4951,Eef1e1,Ifit3,Birc3,Ccl2,Nfkbia,Adrb2,Evl,Csf1,Il15,Dnajb2,Rhoq,Hspa2,Kdm5b,Nr1h3,Ptk2,Pdgfrb,Fzd5,Ptpn2,Ccl8,Gm12185 |
| 8.967e-44 | -99.12 | regulation of molecular function | biological process | GO:0065009 | 2757 | 375 | 20694 | 1406 |
Psmd10,Ccnd1,Tnfsf14,Ikbkg,Asap3,Gja1,Casp3,Ppp2r3a,Hmga2,Psme1,Pdgfc,Mdm2,Dusp8,Cflar,Ppp6r1,Hif1a,Ccnd2,Psme2,Il6,Gem,Prnp,Cacnb3,Thbs1,Plk2,Rgcc,Tagap,Egr1,Eno1,Dnajb4,Gadd45b,Spred3,Txn1,Il1rn,Rcan1,Mark2,Cst7,Ppp1r15a,Tor1aip2,Gdf15,Mmp25,Dusp4,Bcl6,Mdfic,Cx3cl1,Kitl,Cacna1d,Ubash3b,Nlrc5,Fcgr2b,Gch1,Myd88,Met,Ift57,Ripk3,Adar,Cd200,Cycs,Trib1,Nlrc4,Spint2,Stat1,Prdx5,Crkl,Rin2,Ahsa1,Ranbp2,Serpina3f,Lpar1,Lrch1,Ptafr,Pdgfb,Hcls1,Hck,Stat3,Src,Dock4,Dennd1b,Spry2,Dusp16,Birc2,Ccl9,Oas1b,Ppp4r2,Dcp1a,Htr2a,Myc,Pde5a,Ccl7,Hopx,Dcun1d3,Phactr4,Ppp2r1b,Mecp2,Glrx,Apaf1,Tlr9,Slc9a1,Fcgr1,Ahr,Lyn,Ptch1,Lmo4,Htr2b,Hhex,Pik3r6,Cnn3,Trim13,Hp,Arf4,Abr,Bcl2a1d,Acsl1,Higd1a,Dusp2,Rgs3,Stoml1,Tank,Rab9,Hspa1b,Fam72a,Trim14,Ccl5,Serpinb9,Nod1,Cdkn2d,Crim1,Wars,Igf1r,Fgr,Map3k6,Tlr1,C3,Cd74,Actb,Malt1,Oas2,Pde4b,Rnf31,Ccl3,Oasl1,Fzd1,Sod2,Ccl4,Syk,Sh3bp4,Ric1,Pim2,Ccnj,Pml,Pik3r5,Hmox1,Tlr2,Pim1,Uaca,Notch1,Rhoh,Rgs1,Irak2,Nos2,Tab2,Irgm2,Parp9,Spred1,Scn1b,Ptprj,Csf3,Cdc42ep2,Mitd1,Map4k4,Lrp8,Nod2,Nfkbid,Serpine1,Adap2,Homer1,Trim21,Stap1,Zfp36,Gadd45g,Irak3,Adora2a,Aim2,Atp2b4,Abcb1a,Tnfsf4,Nr4a1,Plaur,S100a8,Plau,Hdac1,Keap1,Prkce,Cdk5r1,Nfkb1,Oas1g,Ppp2r5a,Tlr3,Il1b,Pmaip1,Trib3,Mlkl,Lox,Tnfrsf8,Dusp1,Bmp2,Plek,Lhx2,Mefv,Agrn,Il12b,Cd55,P2ry13,Arhgap26,Rffl,Dusp6,Sdc4,Casp8,Cdkn1a,Tnfsf10,Gpr35,Nck1,Hmgn3,Traf5,Ddx58,Rictor,Tnfaip3,Errfi1,Timp1,Jak2,Tlr6,Rap1gap2,Sphk1,Nlrp3,Zc3hav1,Rgs14,Dnaja2,Psma6,Tnfsf15,Arg2,Vcan,Oas1a,Flt1,Lif,Map2k1,Dock10,Fpr2,Bcl2l11,Peli1,Cox17,Csf1,Nupr1,Dnajb2,Ccng2,Sipa1l1,Ifrd1,Hspa2,Antxr1,Tor1aip1,Nr1h3,Ptk2,Pdgfrb,Fzd5,Ptpn2,Ccl8,Eif2ak2,Socs1,Map3k8,Ppm1k,Rnf34,Birc3,Psmb8,Ccl2,Oas3,Ppp1r14b,Adrb2,Arrdc4,Nfkbia,Psmb9,Slamf8,Pbx1,Cav1,Acod1,F11r,Tbc1d13,Lgals9,Mmp9,Sirt1,Plcl2,Ccl22,Ptgs2,Oasl2,Ksr1,Ifit2,Traf1,Mmd,Ralgds,Slpi,Ppp2r2a,Ppp1r12b,Rap2c,Marf1,Adora2b,Dusp5,Plscr1,Tax1bp1,Rapgef2,Hsph1,Icam1,Hk1,Irs2,Kat2b,Uchl1,Rbl1,Cd40,Mtdh,Nlgn2,Parp3,Nqo1,Tbc1d1,Aida,Arid5b,Daxx,Mapkbp1,Tnf,Fam162a,Jun,Bambi,Tpx2,Parp10,Rasgrp1,Ccl12,Angpt1,Crbn,Nfkbib,Serpinb9b,Gfi1,Sele,Il18,Zc3h12a,Serpinb6b,Mvp,Mul1,Ripk2,Traf2,Nek6,Il18rap,Casp1,Ccne1,Hap1,Trim26,Nfkbil1,Casp4,Fas,Pkp4,Mtcp1,Elmod2,Serpinb2,Edn1,Prkar2b,Dnaja1,Med13,Sav1,Rhoc,Irf4,Dtx3l,Gclm,Itga4,Serpina3g,Cenpe,Cmklr1,Plpp3,Map2k4,Ppp1r15b,Il10,Cx3cr1 |
| 9.944e-44 | -99.02 | negative regulation of cellular process | biological process | GO:0048523 | 4654 | 538 | 20694 | 1406 |
Znrf3,Cenpj,Mecp2,Dcun1d3,Tulp3,Phactr4,Vegfc,Hopx,Slc9a1,Tlr9,Pf4,Ddit4,Scyl2,Glrx,Ezr,Parp14,Dusp16,Birc2,Klf2,Spry2,Myc,Pde5a,Htr2a,Clec2d,Zeb1,Ccl9,Dync1i2,Cxcl10,Xaf1,Ero1l,Pdgfb,Serpina3f,Lrch1,Lpar1,Egr3,H2-Ab1,Hck,Stat3,Src,Smpdl3b,Sema3c,Gpr68,Hcls1,Bcor,Stat1,Prdx5,Spint2,Hat1,Crkl,Adar,Cd200,Ncoa5,Trib1,Tarm1,Swap70,Hk3,Optn,Mndal,Plaat3,Kdr,Gfpt1,Nlrc5,Ubash3b,Cx3cl1,Mdfic,Kitl,Mafk,Myd88,Met,Zfp281,H3f3b,Ift57,Dcbld2,Arid5a,Fcgr2b,Siglece,Dnajb4,Cxcl14,Eno1,Kmt5a,Egr1,Pmepa1,Rgcc,Notch2,Zhx2,Ppp1r15a,Bcl6,Gdf15,Dusp4,Rnd1,Cgas,Il1rn,Txn1,Spred3,Gadd45b,Cst7,Rcan1,Ccnd2,Itga5,Hif1a,Il6,Kdm4a,Dusp8,Jag1,Ciita,Cflar,Sap30,Prnp,Fbxo4,Mt1,Thbs1,Plk2,N4bp1,Grk3,Cd34,Ctsc,Samhd1,Rel,Sema4a,Gja1,Itgav,Casp3,Ikbkg,Hk2,Ccnd1,Tnfsf14,Nr4a3,Psmd10,Zmynd15,Crlf3,Relb,Mdm2,Gpr132,Ppp2r3a,Hmga2,Pttg1,Mapkapk2,Ets2,Abcb1a,Atp2b4,Ptger4,Mov10,Adora2a,Hdac1,Nr4a1,Hinfp,Plaur,Acvr1,Tnfsf4,Tsku,Trim21,Stap1,Xrn1,Tent2,Carmil1,Tmem176b,Serpine1,Tmsb10,Nod2,Nfkbid,Radx,Ctla2a,Zfp36,Irak3,Gadd45g,Morc3,Htra1,Spred1,Slfn3,Gbp4,Ifi208,Parp9,Sesn3,Asns,Gng4,Gcnt2,Csf3,Dyrk2,Map4k4,Ptprj,Tlk2,Nmi,Ass1,Nfkbie,Xcr1,Klf8,Uaca,Pim1,Hmox1,Tlr2,Cd300lf,Rhoh,Notch1,Pid1,Rgs1,Sh3bp4,Ric1,Pde3b,Ifi204,Sod2,Fzd1,Noct,Milr1,Bfar,Prdm1,Ago3,Eya4,Pim2,Pml,Ciapin1,Phip,Wars,Ankrd17,Larp1,Igf1r,Ccl5,Serpinb9,Rabgef1,Jdp2,Ifnb1,Cdkn2d,Actb,Junb,Rnf31,Pde4b,C3,Cd74,Higd1a,Atm,Tent4a,Nes,Cd80,Ahrr,Abr,Bcl2a1d,Whamm,Tank,Cdyl,Fam129a,Hspa1b,Cd38,Timeless,Fam72a,Dusp2,Rgs3,Lmo4,Htr2b,Ptch1,Ahr,Ifi209,Clcf1,Chst11,Lyn,Tnip1,Ncoa7,Il4ra,Slc7a11,Kremen1,Ier3,Klf3,Arf4,Dhx58,Hhex,Grina,Hp,Axl,Irf8,Apobec3,Rnf34,Plekhn1,Arid4a,Socs3,Tnc,Eef1e1,Pdpn,Socs1,Pnpt1,Eif2ak2,Slfn1,Aebp2,Stat5a,Ppp1r14b,Slamf8,Dcp2,Slc30a1,Adrb2,Nfkbia,Evl,Sco1,Birc3,D1Ertd622e,Mllt6,Spen,Antxr1,Hspa2,S1pr2,Ifrd1,Nupr1,Csf1,Il15,Dnajb2,Pdgfrb,Cebpd,Fzd5,Ptpn2,Prag1,Kdm5b,Etv6,Nr1h3,Tle3,Rab3ip,Ptk2,Flt1,Arg2,Lif,Gpc1,Peli1,Bcl2a1a,Nr3c1,Eif4g2,Map2k1,Timp1,Tlr6,Jak2,Errfi1,Rap1gap2,Cdyl2,Sphk1,Vasn,Inhba,Tnfaip3,Ptges,Tnfrsf1b,Rnf139,Plac8,Ifi211,Nlrp3,Akt3,Rgs14,Dusp6,Bcl2a1b,Cacybp,H2-Aa,Rffl,P2ry12,Acvrl1,Gpr35,Nck1,Tmem176a,Katna1,Sdc4,Abcc1,Ifi207,Phf6,Cdkn1a,Rbbp8,Casp8,Nampt,Stxbp3,Tmem67,Mosmo,Clic4,Srgn,Tnip3,Sinhcaf,Ednrb,Samsn1,Bnip3,Ifi214,Il12b,Agrn,Mefv,Acvr1b,Dusp1,Mid1,Cnn2,Nmral1,Plek,Cpeb4,Lhx2,Bmp2,Casp2,Zbtb5,Ifi205,Plat,Prkce,Cdk5r1,Ppp2r5a,Tnfrsf14,Nfkb1,Acp5,Btg2,Rfx5,Il1b,Pim3,Isg15,Trib3,Pmaip1,Hspa1a,Cenpe,Plpp3,Serpina3g,Tspo,Rab11fip1,Irf1,Phlpp1,Ppp1r15b,Intu,Map2k4,Dach1,Cx3cr1,Il10,Serpinb2,Edn1,Cish,Sema4c,Socs7,Prkar2b,Dnaja1,Trip13,Nsd3,Fas,Irf4,Svbp,Gclm,Dtx3l,Sav1,Ptgir,Sgk3,Mmp14,Traf2,Usp25,Tmem178,Rhbdf2,Mvp,Serpinb6b,Tmod3,Lrp4,Mul1,Hlx,Znfx1,Stk40,Clec5a,Nfkbil1,Tut7,Ldlr,Ccne1,Ifi203,Hap1,Jarid2,Crbn,Foxp4,Gpr18,Frmd4a,Osgin2,Zc3h12a,Fgl2,Il18,Tomm70a,Serpinb9b,Chmp4b,Slfn2,Trip10,Prokr1,Gfi1,Stxbp1,Bambi,Cited2,Mapkbp1,Plk3,Tnf,Il1a,Daxx,Jun,Tcf4,Rsad2,Angpt1,Ikzf1,Mxd1,Pilrb1,Caml,Ccl12,Asah2,Parp10,Sertad3,Atf3,Dr1,Mtdh,Rbl1,Pfkl,Icam1,Hk1,Uchl1,Irs2,Kat2b,Nqo1,Max,Rpgrip1l,Arid5b,Aida,Insl6,Gclc,Parp3,Casz1,Ddx4,Nfil3,Slpi,Ptgs2,Ifi213,Dusp5,Tax1bp1,Rapgef2,Hsph1,Mier3,Spn,Rap2c,Marf1,Cd86,Adora2b,Acod1,Itpr1,Riox2,Sqstm1,Dbnl,Trim30a,Pbx1,Myadm,Klf7,Cav1,Osm,Etv3,Sirt1,Mmp9,Arel1,Plcl2,Cd274,Lgals9,Il15ra |
| 1.112e-43 | -98.90 | GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_DN | MSigDB lists | GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_DN | 162 | 79 | 15632 | 1249 |
Edn1,Parp14,Katna1,Il18bp,Ifit1bl1,Gsdmd,Nlrc5,Rnf114,Ciita,Tspo,Pttg1,Rtp4,Procr,Isg20,Slpi,Cd69,Il18rap,Birc3,Ifit3,Rel,Ogfr,Gem,Lcn2,Lap3,Cd300lf,Tagap,Ifi35,Casp7,Filip1l,Stat1,Parp11,Lpar1,Aida,Slc25a22,Ifit3b,Cish,Batf2,Dbnl,Gbp4,Gbp9,Ifi44,Nfkbie,Treml2,Rsad2,Tapbp,Dhx58,Ifit2,Nod1,Psme1,Nupr1,Rab19,Icam1,Upp1,Usp18,Stat2,Socs1,Rnf135,Ube2l6,Nmi,Il12rb1,Dgka,Adora2a,Parp12,Slc31a2,Nampt,Ifit1bl2,Snx10,Ccl5,Hopx,Samsn1,Plat,Tnfsf10,Epsti1,Trafd1,Rnf19b,Parp3,Slc43a3,Cxcl10,Serpinb9 |
| 1.330e-43 | -98.73 | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP | MSigDB lists | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP | 105 | 64 | 15632 | 1249 |
Ifi207,Tap1,Samhd1,Nfkbiz,Fas,Ifi214,Irgm2,Il18bp,Nfkbia,Ifit1bl1,Plac8,Ccl12,Msr1,Ifi35,Stat1,Ifi204,Irf1,Ifit3b,Ifi211,Procr,Psme2,Ifi203,Psmb8,Irf8,Ifit3,Marco,Mndal,Gbp7,Cd14,Gbp2,Hck,Psme1,Atp11a,Icam1,Usp18,Cd74,Socs1,Gbp3,Psmb10,Isg15,1110038F14Rik,Ly75,Fgl2,Tapbp,Ifi213,N4bp1,Psmb9,Ifi205,Ifi209,Vcam1,Il1rn,H2-Ab1,Rnf19b,Cxcl10,Ifi208,H2-Aa,Wars,Uba7,Nampt,Ifit1bl2,Snx10,Lcp2,Tap2,Irf7 |
| 2.015e-43 | -98.31 | GO_RESPONSE_TO_EXTERNAL_STIMULUS | MSigDB lists | GO_RESPONSE_TO_EXTERNAL_STIMULUS | 1648 | 293 | 15632 | 1249 |
Fzd1,Vasp,Cxcl2,Nrp2,Asns,Ppp1r15a,Flrt2,Fosb,Fcgr4,Pde4b,Ccl5,Vcam1,Nfkb2,Irak2,Tlr3,Sele,Dhx58,Rsad2,Tnc,Ifi44,Gbp9,H2-Q6,Tnf,Tnfaip3,Cd14,Lipg,Upp1,Slc9a1,Fabp7,Nfkbib,Slpi,Sema3c,Mndal,Casp8,S100a8,Nfkb1,Ikbkg,Cdkn1a,Jak2,Ccl4,Trib1,Lyn,Sema4c,Ptk2,Max,Phlpp1,Ifnb1,Stap1,Spn,Plac8,Nr4a1,Eif2ak2,Ass1,Syk,Ifi207,Il15,Slc16a1,Ifi214,Nck1,Ddx60,Btg2,Ifi208,Scn1b,Tlr1,Cd86,Ifit1bl2,Junb,Gch1,Cmpk2,Ptgs2,Pim1,Clec4d,Il12b,Ptprj,Psmb9,Eno1,Ifi205,Axl,Ifi213,Ifnar1,Casp1,Nod1,Icam1,Sphk1,Fgr,Nfkbil1,H2-Q7,Pml,Ccrl2,Leng9,Plscr1,Tnfsf14,Il10,P2ry2,Clec4n,Clic5,Irf1,Acsl1,Tlr2,Sema4a,Tnfsf4,Socs3,Itpkc,Kif5c,Il18bp,Nqo1,Ccr3,Il6,Peli1,Ccl2,Jun,Cx3cr1,H2-Q4,Nfkbia,Sbds,Ccl12,Samhd1,Ifna1,Plau,Ccl22,Il4ra,Tlr6,Mapkapk2,Mmp13,Ddit4,Ext1,Fzd5,Serpine1,Map2k1,Pdgfrb,Irf7,H2-Eb1,Ccr1,Gja1,Ptges,Il1b,Cxcl1,Ikbke,Lrp11,Adora2b,Il18,Nr4a3,Hp,Hmox1,Ripk2,Mecp2,Cp,Slc39a4,Tnfsf8,Batf2,Ifi209,Csf3r,Ankrd17,Oas3,Ifit2,Apaf1,Ifna2,Irak3,Ccl3,Batf,Myd88,Ifih1,Trim56,Isg20,Ifi211,Zfp36,Cav1,Nos2,Tnfrsf1b,Ednrb,Lhx2,Gbp2b,Odc1,Ifi204,Lpar1,Tnip3,Itga9,Map2k4,Ifit3b,Tlr9,Cpeb4,Hmgcs1,Mtdh,Egr3,Ptgir,Oasl1,Pim2,Optn,Ifna5,Bnip3,Pla2g4a,Mmp14,Nlrc4,Hmga1,Gsdmd,Cnn2,Itgav,Klf7,Zc3hav1,Il27,Cd80,Clec4e,Gpc1,Tspo,Fpr2,Nr1h3,Cx3cl1,Cdk5r1,Fas,Evl,Cdkn2d,Csf3,Oas2,Wdr59,Pdgfb,Ifna6,Cnp,Plaur,Vegfc,Gng12,Pf4,Cmklr1,Elmod2,Ptafr,Serpinb9,Fpr1,Cxcl10,Ptger4,Oas1g,Ldha,Zc3h12a,Mdm2,Ccnd1,Casp3,Egr2,Gbp4,Cd40,Slc2a1,Src,Apobec3,Ifit1,Notch1,Hck,Tnfrsf8,Stat2,Hif1a,Cd180,Ddx58,Isg15,Socs1,Trim12c,Malt1,Mthfr,Oas1a,Sirt1,Hat1,Met,Ifi203,Casp2,Irf8,Ifit3,Ptch1,Ccne1,Trem1,Xcr1,Gfi1,Pik3cd,Adrb2,Fam111a,Stat1,Nod2,Cxcl14,Edn1,Irf4,Kcnj2,Prkce,Fos,Dock4,Ezr,Nlrc5,Ifit1bl1,Rab32,Flt1,Bcl2l11,Flrt3,Tnfrsf14,Angpt1,Slc25a25,Adar,Htr2a,Nlrp3,Atf3,Abr |
| 2.033e-43 | -98.30 | GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_UP | MSigDB lists | GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_UP | 189 | 85 | 15632 | 1249 |
Gclm,Irf4,Ccl2,Ptpn2,Gadd45b,Hivep2,Bcl2l11,Bcl2a1b,Ifi207,Tap1,Zc3hav1,Ciita,Fcgr1,Ifi214,P2ry14,Ccrl2,Oas1a,Xaf1,Ifi203,Tdrd7,Cd69,Isg20,Trim21,Ifi211,Zfp36,Ifit3,Irf8,Lmo4,Casp4,Mndal,Gem,Cdkn1a,Tnfaip2,Irf1,Ifi204,Trib1,Acsl1,Ifit3b,Ifi35,Socs3,Oasl1,Rsad2,Bcl2a1d,Ifi44,Arid5a,Ifi209,Ifi205,Tnf,Klf6,Ifit2,Ifi213,Gbp2,Hck,Mvp,Batf,Stat2,Icam1,Isg15,Socs1,Jmjd6,Pml,Wars,Oas2,Trim26,Pdgfb,Ube2l6,Ifi208,Tlr1,Cd86,Tap2,Lcp2,Irf7,Junb,Plek,Slc31a2,Gch1,Trafd1,Sp110,Bcl2a1a,Tnfsf10,Pim1,Cxcl10,Rnf19b,Oas1g,Dusp5 |
| 6.629e-43 | -97.12 | regulation of cytokine production | biological process | GO:0001817 | 677 | 155 | 20694 | 1406 |
Il27,Angpt1,Myd88,Met,Pml,Casp8,Fcgr2b,Arid5a,Rasgrp1,Syk,Rnf135,Ccl4,Rsad2,P2ry2,Ccl3,Il1a,Ifi204,Cx3cl1,Tnf,Mapkbp1,Pde4b,Bcl6,Cd14,Gsdmd,Malt1,C3,Cd74,Ccdc88b,Tlr1,Mefv,Il12b,Cgas,Il1rn,Cd40,Fgr,Ankrd17,Ifnb1,Nod1,Rgcc,Hk1,Ccl5,Srgn,Egr1,Rabgef1,Cd34,Spn,Thbs1,Tnfsf9,Prnp,Rel,Adora2b,Il6,Hif1a,Hilpda,Ptgs2,Tnfrsf8,Acp5,Sirt1,Irf8,Axl,Mapkapk2,Lgals9,Cd83,Cd274,Isg15,Dhx58,Il1b,Tlr3,Ifi205,Ifnar1,Acod1,Htr2b,Itgav,F11r,Il4ra,Relb,Nfkb1,Osm,Tnfrsf14,Lyn,Nr4a3,Trim30a,Pf4,Tlr9,Hdac1,Irf1,Ccl2,Il10,D1Ertd622e,Ezr,Cx3cr1,Tnfsf4,Ptger4,Mcoln2,Cmklr1,Stat5a,Tspo,Eif2ak2,Aim2,Socs1,Irak3,Zfp36,Fzd5,Irf4,Ddx60,Itgb8,Ifih1,Klf2,Nod2,Serpine1,Il15,Nfkbil1,Casp4,Stat3,Src,Icosl,Peli1,Clec5a,Casp1,Ptprj,Nmi,Klrk1,Arg2,Ptafr,Traf2,Tnfsf15,Ripk2,Mul1,Gbp4,Nos2,Optn,Ifi211,Clec4n,Il18,Zc3h12a,Tnfrsf1b,Zc3hav1,Nlrp3,Mndal,Sphk1,Errfi1,Stat1,Jak2,Tlr6,Il12rb1,Tarm1,Irf7,Tnfaip3,Ripk3,Tlr2,Hmox1,Ddx58,Clec4e,Gpr18,Cd200 |
| 8.636e-43 | -96.86 | immune effector process | biological process | GO:0002252 | 454 | 124 | 20694 | 1406 |
Oas2,Ifitm1,Bnip3,C3,Cd55,Cd180,Cd74,Il12b,Nt5c3,Cgas,Cd40,Ifnb1,Notch2,Icam1,Rgcc,Tagap,Serpinb9,Prdx1,Milr1,Ifna6,Myd88,Trim56,Pml,Fcgr2b,Rasgrp1,Syk,Rsad2,Oasl1,Plcl2,Trim34a,Ifna1,Isg15,Dhx58,Tlr3,Ifnar1,Ifit1bl2,Rtp4,Il4ra,Relb,Oas1g,Lyn,Nr4a3,Prkce,Trim30a,C1rl,Slfn8,Spn,Trem1,Plscr1,Isg20,Sema4a,Ctsc,Samhd1,Cd86,Il6,Ifit1bl1,Gbp2b,Ifit1,Oasl2,Ifit2,Jag1,Gadd45g,Dtx3l,Irf4,Ddx60,C1ra,Rnf19b,Oas1b,Ifih1,Nod2,Fas,Dennd1b,Tlr9,Fcgr1,Batf,Irf1,Oas3,H60b,Cx3cr1,Ifit3,Ddit4,Irf2,Ptger4,Ifna2,Apobec3,Slfn9,Trim12a,Shfl,Eif2ak2,Dnase1l3,Pou2f2,Il18,Fgl2,Itgal,Swap70,Zc3hav1,Nlrp3,Serpinb9b,Zbp1,Mx1,Stat1,Mx2,Irf7,Tnfaip3,Clec4d,Ddx58,Adar,Clec4e,Treml4,Stat3,Icosl,H2-Ab1,Stat2,Il18rap,Stx11,Ifit3b,Dock10,Raet1e,Cxcl9,Ifna5,Oas1a,Cxcl10,Ifna4,Parp9 |
| 9.637e-43 | -96.75 | cellular response to chemical stimulus | biological process | GO:0070887 | 2632 | 361 | 20694 | 1406 |
Vrk2,Larp1,Igf1r,F830016B08Rik,Nox1,Phip,Nod1,Ifnb1,Srm,Cxcl2,Ccl5,Pde4b,Oas2,Malt1,Actb,Junb,Cd74,Stat4,Sh3bp4,Pde3b,Syk,Ccl4,Sod2,Ccl3,Ifi204,Rab20,Col4a2,Zyx,Ccr1,Pml,Ptch1,Htr2b,Lyn,Il4ra,Slc7a11,Ifi209,Ahr,Hp,Irf8,Axl,Atm,Cd80,Higd1a,Ifit1,Gbp2b,Acsl1,Fos,Ahrr,Timeless,Hspa1b,Tank,Stoml1,Stap1,Serpine1,Flrt2,Nod2,Igtp,H2-Q7,Irak3,Zfp36,Ptger4,Atp2b4,Ehd1,Egln3,Aim2,Hdac1,Cdc42ep4,S100a8,Acvr1,Nr4a1,Tnfsf4,Uaca,Flnb,Gsta3,Pim1,Tlr2,Hmox1,Cd300lf,Irak2,Tiparp,Pid1,Gm4841,Notch1,Cxcl9,Ifi208,Ifna4,Sesn3,Irgm2,Nos2,Gbp4,Cd69,Cdc42ep2,Gcnt2,Csf3,Cmpk2,Xcr1,Nmi,Stx11,Fut8,Cxcl14,Vcam1,Eno1,Calcrl,Egr1,Rab10,Rgcc,Gdf15,Ppp1r15a,Cgas,Il1rn,Kdm6b,Egr2,Kdr,Gbp9,Cx3cl1,Irgm1,Myd88,Serp1,Arid5a,Gch1,Fcgr2b,Hk2,Casp3,Ccnd1,Nr4a3,Mdm2,Pdgfc,Mapkapk2,Il6,9930111J21Rik1,Hif1a,Cflar,Mt1,Thbs1,Prnp,Trem1,Pde1b,Klf2,Ifih1,Tgtp1,Ccrl2,Csf3r,Birc2,Spry2,Dock4,Myc,Dcp1a,Fcgr4,Zeb1,Ccl9,Mecp2,Vegfc,Iigp1,Cxcl1,Ccl7,Gbp2,Slc9a1,Pf4,Tlr9,Apaf1,Stip1,Ezr,Ddit4,Glrx,Crkl,Flrt3,Prdx5,Stat1,Cxcl3,Il12rb1,Ripk3,Optn,Mndal,Ero1l,Ebi3,Ak4,Pdgfb,Klrk1,Cxcl10,Ptafr,Lpar1,Lrch1,Egr3,H2-Ab1,Src,Stat3,Lcn2,Gbp3,Hcls1,Gbp8,Mtdh,Slc16a1,Kat2b,Irs2,Icam1,Arid5b,Nqo1,Cd180,Il13ra1,Selenow,Cited2,Bambi,Stxbp1,Jun,Fam162a,Tnf,Plk3,Daxx,Il1a,Prdx1,Atf3,Ccl12,Asah2,Acod1,Itpr1,Cav1,Osm,Cxcl11,Ccl22,Etv3,Mmp9,Sirt1,Il15ra,Cd274,Cyfip1,Nfil3,Klf6,Ifit2,Ifi213,Rapgef2,Plscr1,Cd86,Socs7,Dnaja1,Hvcn1,Esd,Fas,Gclm,Itga4,Tgtp2,Casp7,Ccr3,Hspa1a,Gbp7,Irf1,Cx3cr1,Il10,Slc31a1,Nfkbib,Sbds,Zc3h12a,Il18,Gfi1,Traf2,Ifna5,Mul1,Ripk2,Casp4,Nfkbil1,Ifi203,Hap1,Jarid2,Casp1,Ldlr,Il18rap,Clic4,Stxbp3,Tnip3,Bnip3,Ifitm1,Ifi214,Ednrb,Cd14,P2ry13,Il12b,Cacybp,Gm5431,Srxn1,P2ry12,Mt2,Ifna6,Acvrl1,Gpr35,Agtrap,Ifi207,Etv5,Pla2g4a,Abtb2,Abcc1,Ifi205,Tlr3,Ifnar1,Nfkb1,Cdk5r1,Prkce,Keap1,Ifna1,Trib3,Il1b,Dusp1,Acvr1b,Il2rg,Saa3,Lox,Phgdh,Cpeb4,Nrp2,Nmral1,Bmp2,Hspa2,Rhoq,Csf1,Il15,Gsr,Ccl8,Gm12185,Ptpn2,Pdgfrb,Ptk2,Fosb,Kdm5b,Ch25h,Nr1h3,Gm4951,Eef1e1,Socs3,Ifna2,Stat5a,Socs1,Eif2ak2,Pnpt1,Slamf8,Evl,Nfkbia,Adrb2,Ccl2,Birc3,Ifit3,Sphk1,Tlr6,Jak2,Irf7,Tnfaip3,Inhba,Pgk1,Ddx58,Vasn,Ifi211,Ifi47,Tnfrsf1b,Itga9,Gramd1a,Akt3,Zc3hav1,Nlrp3,Flt1,Nr3c1,Fpr2,Stat2,Snx10,Pdk3 |
| 1.059e-42 | -96.65 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | 396 | 124 | 15632 | 1249 |
Ifi205,Ifi213,Dusp1,Plekhf2,Apobec3,Cebpd,Nr3c1,Setdb2,Spata13,Ddx58,Trim12c,Mxd1,Gbp2,Klf2,Rnaset2a,Txn1,Nampt,Ifit1bl2,Gch1,Oas2,Ube2l6,Nmi,Ifi208,Tgfbi,Cxcl10,Fpr1,Ptger4,Rnf19b,Herc6,Oas1g,Il15ra,Lacc1,5430427O19Rik,Cmpk2,Plcl2,Cmklr1,Tnfsf10,Tiparp,Ifit1bl1,Samd9l,I830077J02Rik,Xrn1,Dmxl2,Egr1,Pfkfb3,Ifit3,Il10,Marco,Plekha2,Sirt1,Oas1a,Ifi203,Ms4a6d,Sema4a,Socs3,Ppa1,Rnaset2b,Oas3,Rhbdf2,Ifi209,Cd302,Bcl6,Csf3r,Ifit2,Klf6,Abcc5,Fgl2,Dhx58,Rsad2,Sat1,Ifi44,Usp18,Ifih1,Parp10,Aim2,Nupr1,Cd38,Ncoa7,Myd88,Gnb4,Cd14,Lcp2,Fcgr4,Snx2,Stxbp3,Fcho2,Frmd4a,Spire1,Il18,Map3k8,Arid5b,Hmox1,Epsti1,Sp110,Cited2,Gadd45b,Klf3,Spn,Sod2,Rin2,Ctsc,Bnip3,Fpr2,Ifi214,Fas,Aff1,Ifi207,Me1,Slfn5,Mndal,Kctd12,Xaf1,Ifi211,Isg20,Trim14,Ociad1,Zfp36,Ifi204,Ifit3b,Lyn,Max,Oasl1,Rbms1,Notch2 |
| 1.385e-42 | -96.38 | GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_DN | MSigDB lists | GSE13485_PRE_VS_POST_YF17D_VACCINATION_PBMC_DN | 175 | 81 | 15632 | 1249 |
Parp14,Samd9l,Parp9,I830077J02Rik,Eif2ak2,Ifit1bl1,Plac8,Cx3cr1,Msr1,Zbp1,Slamf7,Adar,Pnpt1,Ifi207,Tap1,Samhd1,Ddx60,Rtp4,Ifi214,Ifi211,Timeless,Psme2,Oas1a,Tdrd7,Ifi203,Xaf1,Psmb8,Ifit3,Mndal,Adap2,Lap3,Vrk2,Ifi35,Oasl1,Stat1,Ifi204,Ifit3b,Batf2,Ifi44,Ubtd2,Fgl2,Dhx58,Rsad2,Ifi213,Ifit2,Ifnar1,Oas3,Ifi205,Ifi209,Myd88,Aim2,Parp10,Ddx58,Stat2,Kmo,Usp18,Trim12c,Ifih1,Isg15,Dtx3l,Ube2l6,Ifi208,Oas2,Parp12,Ifit1bl2,Fcgr4,Rgl1,Cnp,Irf7,Atp6v1d,Acsl5,Gtpbp2,Epsti1,Sp110,Acp2,Cmpk2,Herc6,Oas1g,Rcan1,Slc43a3,Cxcl10 |
| 1.573e-42 | -96.26 | GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_UP | MSigDB lists | GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_UP | 154 | 76 | 15632 | 1249 |
Bst1,Mmp13,Adora2a,Phlda1,Osm,Sipa1l1,Pdgfrb,Pik3r6,Slc7a2,Gdf15,Ccl5,Pkp4,Fmnl2,Il1b,Ptges,Cxcl1,Gtpbp2,Cmklr1,Serpinb2,Chic2,Ptgs2,Fpr1,Kdm6b,Traf3ip2,Zc3h12a,Rbpms,Micall2,Dusp8,Rab11fip1,Egr2,Rffl,Slc15a3,Rnf24,Rhbdf2,Notch1,Mdfic,Tnfaip3,Tmc3,Tal2,Il1a,Upp1,Cd74,Traf1,Csrnp1,Nupr1,Slc39a14,Nos2,Lcn2,Rabgef1,Abtb2,Tnfrsf1b,Trem1,Lrrc8c,Gfi1,Notch2,Jak2,Tnip1,Ccl4,Sema4a,Ier3,Acsl1,Kremen1,Dtnb,Pla2g4a,Edn1,Fcgr2b,Stard5,Ets2,Nr4a1,Gramd1a,Slc7a11,Ahr,Olr1,Il27,F10,Egr1 |
| 1.685e-42 | -96.19 | positive regulation of protein metabolic process | biological process | GO:0051247 | 1669 | 267 | 20694 | 1406 |
Gadd45b,Mefv,Agrn,Il12b,Txn1,Il1rn,Ednrb,Ppp1r15a,Gdf15,Mmp25,Bcl6,Rgcc,Egr1,Notch2,Tmem67,Sdc4,Fcgr2b,Arid5a,Casp8,Cdkn1a,Myd88,Serp1,Tnfsf10,Met,Acvrl1,Ift57,Rnf19a,Ifna6,Nck1,Mdfic,Cx3cl1,Kitl,Kdr,Ppp2r3a,Il1b,Polr2g,Mapkapk2,Pmaip1,Trib3,Psme1,Ifna1,Pdgfc,Mlkl,Mdm2,Cdk5r1,Prkce,Psmd10,Ccnd1,Ppp2r5a,Tnfrsf14,Ikbkg,Gja1,Casp3,Tlr3,Ctsc,Bmp2,Rel,Fbxo4,Prnp,Grk3,Thbs1,Plk2,Tnfrsf8,Mid1,Cflar,Acvr1b,Itga5,Ccnd2,Psme2,Il6,Nr1h3,Ccl9,Ptk2,Rnf19b,Pdgfrb,Fzd5,Htr2a,Ccl8,Pde5a,Myc,Il15,Csf1,Nupr1,Dnajb2,Gsap,Spry2,Birc2,S1pr2,Klf2,Hspa2,Antxr1,Parp14,Ezr,Birc3,Ccl2,Arrdc4,Adrb2,Apaf1,Tlr9,Nfkbia,Fcgr1,Eif2ak2,Ccl7,Glipr2,Stat5a,Map3k8,Ifna2,Rbpms,Dcun1d3,Vegfc,Mecp2,Scimp,Nlrp3,Rnf139,Tnfrsf1b,Ripk3,Cysltr2,Rictor,Inhba,Cycs,Trib1,Tnfaip3,Nlrc4,Stat1,Jak2,Tlr6,Crkl,Sphk1,Map2k1,Eif4g2,Hcls1,Fpr2,Stat3,Bcl2l11,Src,Peli1,Tnks1bp1,Tnfsf15,Lpar1,Ptafr,Flt1,Lif,Pdgfb,Tlr1,Gclc,C3,Cd74,Malt1,Icam1,Ccl5,Jdp2,Kat2b,Ifnb1,Nod1,Phip,Nox1,Larp1,Igf1r,Cd40,Map3k6,Rasgrp1,Ccl12,Pml,Ccr1,Angpt1,Il27,Pik3r5,Il1a,Ccl3,Daxx,Tnf,Mapkbp1,Plk3,Fzd1,Fam162a,Jun,Ccl4,Syk,Tpx2,Pik3r6,Lgals9,Sirt1,Mmp9,Ier3,Arel1,Ccl22,Clcf1,Trim30a,Tnip1,Osm,Cav1,Lyn,Htr2b,Sqstm1,Rap2c,Fam129a,Tank,Hspa1b,Spn,Rapgef2,Hsph1,Ahrr,Ankib1,Ptgs2,Ksr1,Mmd,Acsl1,Higd1a,Cd80,Atm,Mmp14,Cop1,Irf4,Gadd45g,Fas,Nsd3,Lrp8,Nod2,Mtcp1,Sema4c,Stap1,Edn1,Map2k4,Ppp1r15b,Acvr1,Plaur,Cx3cr1,S100a8,Irf1,Hdac1,Aim2,Cenpe,Hspa1a,Atp2b4,Ptger4,Plpp3,Notch1,Il18,Zc3h12a,Tiparp,Ythdf1,Irak2,Tlr2,Pim1,Marco,Uaca,Ptprj,Nmi,Ldlr,Casp1,Jarid2,Csf3,Gcnt2,Icosl,Map4k4,Casp4,Rnf14,Tab2,Irgm2,Ifna4,Lrp4,Parp9,Mul1,Ripk2,Ifna5,Traf2,Nek6 |
| 1.927e-42 | -96.05 | GSE17721_CTRL_VS_POLYIC_4H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_4H_BMDC_DN | 180 | 82 | 15632 | 1249 |
Ptgs2,Slamf8,Clec5a,Atp10a,Smc5,Parp3,Epsti1,Hcar2,Il1rn,Gtpbp2,Cldnd1,Mitd1,Serpinb2,Ppp1r15a,Pde4b,Nampt,Gch1,G3bp2,Parp12,Upp1,Tab2,Fabp3,Agtrap,Nupr1,Stau1,Cd38,Gbp2,Crlf3,1600014C10Rik,Psmb9,Ttc39c,Csf3r,Ehd1,N4bp1,Ifnar1,Spryd7,Rsad2,Dhx58,Cebpd,Nr3c1,Carhsp1,Ms4a6d,Mtmr14,Etnk1,Endod1,Ell2,Dtx2,Plekhn1,Cdkn1a,Znrf1,Kdr,Cd82,Cav1,Zc3h12c,Irf8,Casp4,Adap2,Pdk3,Il18rap,Tdrd7,Procr,Flnb,Xrn1,Abr,Atf3,Usp25,Mapkapk2,Palld,Tap1,Col4a2,Rbm43,Znfx1,Ets2,Adhfe1,Ccl12,Vcan,Il18bp,Mid1,Irgm2,Stard5,Ppp2r5a,Dusp2 |
| 3.054e-42 | -95.59 | positive regulation of metabolic process | biological process | GO:0009893 | 3555 | 442 | 20694 | 1406 |
Lgals9,Sirt1,Mmp9,Arel1,Ccl22,Spire1,Trim30a,Pbx1,Osm,Klf7,Cav1,Acod1,Sqstm1,Rap2c,Adora2b,Plscr1,Spn,Pik3cd,Rapgef2,Hsph1,Ptgs2,Ksr1,Ier2,Bcl9,Mmd,Casz1,Klf6,Nfil3,Gclc,Pou3f1,Parp3,Arid5b,Max,Icam1,Irs2,Jmjd6,Kat2b,Dync1h1,Dr1,Cd40,Mtdh,Mycl,Taf4b,Sertad3,Rasgrp1,Ccl12,Atf3,Angpt1,Ikzf1,Il27,Il1a,Daxx,Mapkbp1,Tnf,Plk3,Fam162a,Jun,Pcgf5,Tcf4,Bambi,Cited2,Tpx2,Gfi1,Sele,Il18,Zc3h12a,Ythdf1,Marco,Ldlr,Casp1,Jarid2,Hivep2,Casp4,Rnf14,Lrp4,Mul1,Ripk2,Ifna5,Traf2,Nek6,Med13,Mmp14,Irf4,Dtx3l,Fas,Nsd3,Hmga1,Mtcp1,Resf1,Sema4c,Edn1,Map2k4,Ppp1r15b,Irf2,Il10,Cx3cr1,Irf1,Tspo,Hspa1a,Cmklr1,Cenpe,Plpp3,Il1b,Tet2,Polr2g,Pmaip1,Trib3,Ifna1,Btg2,Mlkl,Prkce,Cdk5r1,Nfkb1,Ppp2r5a,Tnfrsf14,Ifnar1,Tlr3,Bmp2,Plek,Lhx2,Cnn2,Tnfrsf8,Mid1,Il2rg,Acvr1b,Nfkb2,Mefv,Agrn,Il12b,Tra2a,Ednrb,Bnip3,Tmem67,Sdc4,Pla2g4a,Etv5,Casp8,Nampt,Cdkn1a,Tnfsf10,Acvrl1,Rnf19a,Ifna6,Nck1,Cacybp,Nlrp3,Scimp,Zc3hav1,Rnf139,Tnfrsf1b,Plac8,Hmgn3,Ddx58,Rictor,Pgk1,Inhba,Irf7,Tnfaip3,Tlr6,Jak2,Tcea1,Sphk1,Map2k1,Eif4g2,Stat2,Fpr2,Bcl2l11,Peli1,Nr3c1,Cox17,Wdr43,Tnfsf15,Flt1,Lif,Nr1h3,Kdm5b,Fosb,Etv6,Ptk2,Cebpd,Pdgfrb,Ptpn2,Fzd5,Ccl8,Il15,Nupr1,Csf1,Dnajb2,Gsap,Rhoq,S1pr2,Ifrd1,Antxr1,Hspa2,Spen,Mllt6,Birc3,Ccl2,Batf,Nfkbia,Arrdc4,Adrb2,Med21,Pnpt1,Eif2ak2,Plagl1,Stat5a,Ppm1k,Map3k8,Arid4a,Tnc,Ifna2,Plekhn1,Rbpms,Hhex,Pik3r6,Acsl5,Irf8,Trim13,Ier3,Arf4,Clcf1,Ahr,Tnip1,Il4ra,Ncoa7,Lyn,Htr2b,Lmo4,Ptch1,Helz2,Fam129a,Tank,Hspa1b,Cd38,Timeless,Ahrr,Ankib1,Fos,Acsl1,Higd1a,Cd80,Atm,Tent4a,Tlr1,C3,Cd74,Fabp3,Junb,Malt1,Ccl5,Serpinb9,Jdp2,Ifnb1,Nod1,Wars,Phip,Nox1,Igf1r,Larp1,Psip1,Fgr,Map3k6,Pim2,Ago3,Eya4,Pml,Ccr1,Noct,Prdm1,Pik3r5,Ccl3,Fzd1,Sod2,Ccl4,Syk,Sh3bp4,Stat4,Notch1,Pid1,Irak2,Tiparp,Hmox1,Tlr2,Pim1,Uaca,Tnfsf8,Ass1,Ptprj,Nmi,Csf3,Gcnt2,Dyrk2,Icosl,Map4k4,Nos2,Tab2,Irgm2,Ifna4,Sesn3,Parp9,Hivep3,Itgb8,Cop1,Zfp36,Gadd45g,Lrp8,Nod2,Serpine1,Trim21,Stap1,Tnfsf4,Nr4a1,Acvr1,Plaur,Hinfp,S100a8,Plau,Adam19,Hdac1,Aim2,Ets2,Atp2b4,Ptger4,Mov10,Hmga2,Ppp2r3a,Fubp1,Mapkapk2,Psme1,Pdgfc,Mdm2,Nr4a3,Psmd10,Ccnd1,Relb,Crlf3,Pcx,Ikbkg,Gja1,Casp3,Hk2,Ctsc,Rel,Fbxo4,Prnp,Grk3,Prdm9,Thbs1,Plk2,Jag1,Cflar,Ciita,Hif1a,Itga5,Ccnd2,Psme2,Kdm4a,Il6,Gadd45b,Kdm6b,Txn1,Il1rn,Ppp1r15a,Gdf15,Mmp25,Bcl6,Rgcc,Egr1,Notch2,Fcgr2b,Arid5a,Gch1,Serp1,Myd88,Met,Irgm1,Ift57,Zfp281,Mdfic,Cx3cl1,Kitl,Kdr,Egr2,Nlrc5,Ranbp2,Pou2f2,Optn,Ripk3,Cysltr2,Maff,Adar,Cycs,Trib1,Nlrc4,Stat1,Prdx5,Crkl,Hcls1,Tfec,Lcn2,Stat3,Src,Egr3,Tnks1bp1,Lpar1,Ptafr,Mafg,Pdgfb,Klrk1,Zeb1,Ccl9,Rnf19b,Dcp1a,Plagl2,Htr2a,Myc,Pde5a,Aff1,Spry2,Birc2,Csrnp1,Klf2,Scyl2,Parp14,Ezr,Maml2,Dio2,Spic,Apaf1,Pf4,Tlr9,Fcgr1,Slc9a1,Ccl7,Ell2,Glipr2,Cxcl1,Cenpj,Dcun1d3,Vegfc,Mecp2 |
| 3.261e-42 | -95.53 | GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_DN | MSigDB lists | GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_DN | 181 | 82 | 15632 | 1249 |
Cd38,Gbp2,Tnfaip3,Psme1,H2-Q7,Hif1a,Ddx58,Cd74,Stat2,Socs1,Psmb10,Ifih1,Stat3,Slc15a3,C1ra,Psma6,Ifit2,Klf6,Casp1,Plekhf2,H2-Q6,Psmb9,Rhbdf2,Cd40,Cxcl1,Tnfsf10,Il15ra,Plaur,Glrx,Trafd1,Sp110,Rnf19b,Tlr3,Parp3,Dusp5,Ak4,Cxcl10,Tapbpl,Ube2l6,Nmi,Wars,Oas2,Uba7,Hk2,Maff,Nampt,Ccl5,Tap2,Slc7a2,Il15,Tap1,Samhd1,Fas,Rtp4,Il4ra,Optn,H2-Q4,Rnf114,Sod2,Dock4,Rbms1,Jak2,Dram1,Max,Casp7,Ifi35,Mtmr14,C3,Oasl1,Irf1,Slc25a22,Fam111a,Ifit3b,Isg20,Trim21,Zfp36,Psmb8,Hk1,Tnfrsf1b,Irf8,Ifit3,Lap3 |
| 3.261e-42 | -95.53 | GSE17721_0.5H_VS_8H_CPG_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_8H_CPG_BMDC_DN | 181 | 82 | 15632 | 1249 |
Zeb1,Oas1a,Pou2f2,Eno2,Rel,Cav1,Heatr6,Nos2,Lap3,Lmo4,Gfpt1,Asf1a,Tnfaip2,Idi1,Trem1,Dusp16,Asb13,Pdzd11,Abcb1a,Parp14,Prkce,Tra2a,Ifnb1,Ankrd24,Ccl12,Agrn,Psmd10,Dnaja1,Il15,Pilra,Slamf7,Pnpt1,Enpp4,Chmp4b,Me1,Tap1,Stxbp1,Rtp4,Rab10,Wdfy1,Tmeff1,Wars,Tbc1d13,Slc7a8,Brd2,Ccl5,Tor1aip1,Asah2,Pdgfrb,Serpine1,Vps54,Nfxl1,Clic4,Igf2bp2,Vegfc,Acp2,Fam53c,Slc31a1,Oas1g,Cox18,Ak4,Tbc1d1,Batf2,Tnfsf8,Dennd1b,Tlk2,Ccng2,Psma6,Casp1,Ctu1,Usp53,Rgs14,Psmb9,Crlf3,Ifit1,Prpf38a,Gbp2,Ube2e1,Zfp281,Icam1,Usp18,F11r |
| 3.788e-42 | -95.38 | regulation of phosphorus metabolic process | biological process | GO:0051174 | 1735 | 273 | 20694 | 1406 |
Hhex,Pik3r6,Lgals9,Sirt1,Mmp9,Ier3,Plcl2,Ccl22,Fam20c,Clcf1,Ahr,Myadm,Tnip1,Osm,Lyn,Cav1,Lmo4,Htr2b,Sqstm1,Dusp2,Ppp2r2a,Rap2c,Marf1,Adora2b,Fam129a,Dusp5,Spn,Hsph1,Fam72a,Rapgef2,Ptgs2,Ksr1,Mmd,Acsl1,Higd1a,Cd80,Atm,Tlr1,C3,Cd74,Fabp3,Actb,Malt1,Aida,Icam1,Ccl5,Rabgef1,Irs2,Kat2b,Nod1,Cdkn2d,Ifnb1,Uchl1,Phip,Wars,Nox1,Igf1r,Rbl1,Cd40,Fgr,Vrk2,Map3k6,Rasgrp1,Ccl12,Ccnj,Pml,Ccr1,Atf3,Angpt1,Prdx1,Pik3r5,Il1a,Ccl3,Daxx,Mapkbp1,Tnf,Fzd1,Jun,Ccl4,Syk,Tpx2,Notch1,Rhoh,Pid1,Il18,Zc3h12a,Irak2,Tlr2,Pim1,Marco,Ptprj,Ldlr,Ccne1,Gcnt2,Csf3,Map4k4,Mvp,Gbp4,Tab2,Nos2,Irgm2,Ifna4,Stk40,Lrp4,Parp9,Mul1,Ripk2,Ifna5,Traf2,Spred1,Nek6,Gadd45g,Irak3,Fas,Lrp8,Nod2,Mtcp1,Sema4c,Stap1,Edn1,Prkar2b,Dnaja1,Map2k4,Ppp1r15b,Acvr1,Plaur,Cx3cr1,Irf1,Hdac1,Phlpp1,Adora2a,Bst1,Cenpe,Atp2b4,Ptger4,Plpp3,Ppp2r3a,Il1b,Trib3,Pdgfc,Ifna1,Mlkl,Prkce,Psmd10,Cdk5r1,Ccnd1,Ppp2r5a,Tnfrsf14,Pcx,Ikbkg,Ifnar1,Casp3,Tlr3,Bmp2,Plek,Prnp,Grk3,Thbs1,Lox,Dusp8,Mid1,Cflar,Ppp6r1,Acvr1b,Hif1a,Itga5,Dusp1,Ccnd2,Il6,Spred3,Gadd45b,Il12b,Agrn,Il1rn,Txn1,Rcan1,Ednrb,Ppp1r15a,Samsn1,Gdf15,Dusp4,Rgcc,Egr1,Pmepa1,Notch2,Sdc4,Fcgr2b,Cdkn1a,Myd88,Met,Acvrl1,Ifna6,Nck1,Mdfic,Cx3cl1,Kitl,Dusp6,Kdr,Ubash3b,Nlrc5,Scimp,Ranbp2,Rgs14,Swap70,Ripk3,Cysltr2,Adar,Rictor,Inhba,Pgk1,Tnfaip3,Trib1,Errfi1,Tlr6,Jak2,Crkl,Sphk1,Map2k1,Hcls1,Pdk3,Stat2,Fpr2,Stat3,Src,Tnks1bp1,Tnfsf15,Lpar1,Ptafr,Vcan,Flt1,Lif,Ak4,Pdgfb,Ccl9,Ptk2,Ppp4r2,Pdgfrb,Ptpn2,Fzd5,Htr2a,Ccl8,Pde5a,Myc,Il15,Csf1,Nupr1,Spry2,Ccng2,Dusp16,S1pr2,Hspa2,Ddit4,Parp14,Ezr,Birc3,Ccl2,Ppp1r14b,Adrb2,Tlr9,Fcgr1,Slamf8,Ccl7,Eif2ak2,Slfn1,Socs1,Glipr2,Map3k8,Socs3,Ifna2,Rbpms,Phactr4,Vegfc,Ppp2r1b |
| 4.053e-42 | -95.31 | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN | 177 | 81 | 15632 | 1249 |
Irf2,Parp10,Dtx3l,Ifih1,Isg15,Ddx58,Stat2,Ube2f,Myd88,Nod1,Ncoa7,Cd38,Ifit2,Ifi213,Phf11b,Oas3,Ifi205,Ifi209,Arhgef3,Ifi44,Sat1,Mlkl,Dhx58,Dusp5,Oas1g,Ptger4,Cxcl10,Tnfsf10,Htr2b,Sp110,Trafd1,Il15ra,Epsti1,Gch1,4930523C07Rik,Irf7,Ppm1k,Nmi,Ifi208,Ube2l6,Wdfy1,Trim26,Oas2,Parp12,Usp25,Ddx60,Ifi214,Zbp1,Phf11a,Phf11c,Ifi207,Eif2ak2,D16Ertd472e,Tiparp,Znfx1,Stap1,Peli1,Phactr4,Samd9l,Parp9,Optn,Oasl1,Ifi35,Azi2,Ifi204,Phf11d,Zcchc2,Vrk2,Lap3,Mndal,Irf8,Mov10,Plscr1,Ifi211,Isg20,Trim21,Ifi203,Tdrd7,Xaf1,Trim56,Oas1a |
| 4.053e-42 | -95.31 | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_DN | 177 | 81 | 15632 | 1249 |
Znfx1,Gramd1a,Ifit1bl1,Eif2ak2,Gadd45b,Dusp4,Ifnb1,Optn,Vcan,Peli1,Parp14,Kcnj2,Etv3,Ddx60,Il15,Rel,Irf8,Nfkb1,Tdrd7,Usp12,Ccrl2,Stat4,Lyn,Tnip3,Irf1,Socs3,Pim2,Cd200,Tnip1,Tnfaip2,Rgs1,Clcf1,Birc2,Swap70,Homer1,Dusp1,Psma6,Rsad2,Itgb8,Tnfsf8,Sat1,Rab21,Ifih1,Usp18,Icam1,Ddx58,Csrnp1,Aim2,Relb,Myo10,Rab3ip,Mapkbp1,Batf,Irf7,Cd274,Sesn3,Map4k4,Gch1,Ifit1bl2,Txn1,Nampt,Stx11,Oas2,AA467197,Tbc1d13,Cxcl2,Rapgef2,Wars,Ext1,Map3k8,Cxcl10,Ak4,Kcna3,Dusp5,Ripk2,Herc6,Ptger4,Trafd1,Cmpk2,Irak2,Plat |
| 5.493e-42 | -95.01 | GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN | MSigDB lists | GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN | 182 | 82 | 15632 | 1249 |
Aoah,Nfkbia,Sod2,Cyfip1,Ets2,Cited2,Mmp14,Optn,Mllt6,Dusp4,Atf3,Tmem176b,Egr1,Ciapin1,Fpr2,Nlrp3,Pfkfb3,Slc48a1,Klf7,Clec4n,Birc3,Zc3h12c,Casp4,Pstpip2,Rnf19a,Hivep3,Pla2g7,Tmem176a,Dram1,C3,Itga9,Rab20,Tlr2,Clcn7,Adam19,Fam20c,Cd82,Tnip1,Ehd1,Klf6,Ifnar1,Casp1,Ddhd1,N4bp1,Csf3r,Gpr84,Rffl,Slc15a3,Ccnd1,Nfkbie,Stk40,Marcksl1,Lrch3,Mcoln2,Icam1,Hif1a,Traf1,Slco3a1,Sav1,Ube2f,Etv5,Rgs3,Tnfaip3,Myo10,Relb,Plek,Plk2,Mmp13,Snx2,Cxcl2,Ptger4,Larp1,Naa25,Hp,Slamf8,Ttc39b,Il1rn,Ralgds,Fmnl2,Lacc1,Igf2bp2,Acp2 |
| 5.493e-42 | -95.01 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_DN | 182 | 82 | 15632 | 1249 |
Smc5,Dusp5,Zc3h12a,Ptger4,Kdm6b,Map3k8,Cxcl10,Nr4a3,Il12b,Ptgs2,Adora2b,Serpinb2,Rsbn1,Bcl2a1a,Ppp2r2a,Il1b,Lacc1,Ccl5,Pde4b,Plek,Ppp1r15a,Phlda1,Maff,Cxcl2,Nfkbid,Lif,Csrnp1,Prdm1,Marcksl1,Arg2,Traf1,Icam1,Ccdc88b,Tnfaip3,Lrp4,Ehd1,Tnf,Dusp1,Slc15a3,Bcl2a1d,Stk40,Gsr,Mdm2,Errfi1,Socs3,Filip1l,Itpkc,Ier3,Mefv,Rab20,Odc1,Dnajb4,Trib1,Ccl4,Idi1,Tnfaip2,Rgs1,Clcf1,Cdkn1a,Tagap,Tnfrsf1b,Jdp2,Gem,Ampd3,Nfkbib,Zfp36,Ccrl2,Egr1,Nfkbiz,Irs2,Cdk5r1,Etv3,Pim3,Enpp4,Bcl2a1b,Nfkbia,Ets2,Cited2,Jun,Il6,Dusp2,Ifrd1 |
| 6.882e-42 | -94.78 | GSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_DN | MSigDB lists | GSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_DN | 178 | 81 | 15632 | 1249 |
Isg20,Trim14,Trim21,Ifi211,Plscr1,Psme2,Oas1a,Xaf1,Dcp1a,Tdrd7,Ifi203,Psmb8,Rnf31,Ifit3,Mndal,Lap3,Zcchc2,Ifi35,Oasl1,Parp11,Phf11d,Ifi204,Ifit3b,Ifit1bl1,Morc3,Gsdmd,Eif2ak2,Dnaja1,Phf11a,Adar,Zbp1,Ifi207,Phf11c,Ddx60,Usp25,Ifi214,Rtp4,Trim26,Ube2l6,Ifi208,Nmi,Parp12,Uba7,Oas2,Ifit1bl2,Cnp,Irf7,Gtpbp2,Sp110,Ppp2r2a,Trafd1,Herc6,Fndc3a,Oas1g,Kcna3,Sat1,Ifi44,Fchsd2,Rsad2,Dhx58,Ifi213,Ifit2,Phf11b,N4bp1,Lrp4,Ifi209,Ifi205,Oas3,Myd88,Rnf34,Cd164,Magohb,Psme1,Pml,Prrg4,Usp18,Stat2,Ddx58,Ifih1,Isg15,Trim12c |
| 9.990e-42 | -94.41 | regulation of phosphate metabolic process | biological process | GO:0019220 | 1734 | 272 | 20694 | 1406 |
S1pr2,Hspa2,Dusp16,Ccng2,Spry2,Il15,Nupr1,Csf1,Htr2a,Ccl8,Pde5a,Myc,Pdgfrb,Fzd5,Ptpn2,Ptk2,Ppp4r2,Ccl9,Phactr4,Vegfc,Ppp2r1b,Socs3,Ifna2,Rbpms,Glipr2,Map3k8,Slfn1,Ccl7,Eif2ak2,Socs1,Tlr9,Adrb2,Fcgr1,Slamf8,Ccl2,Ppp1r14b,Parp14,Ezr,Birc3,Ddit4,Crkl,Sphk1,Errfi1,Jak2,Tlr6,Rictor,Inhba,Pgk1,Trib1,Tnfaip3,Ripk3,Cysltr2,Adar,Swap70,Rgs14,Scimp,Ranbp2,Lif,Pdgfb,Ak4,Vcan,Ptafr,Flt1,Tnfsf15,Lpar1,Tnks1bp1,Stat3,Src,Stat2,Fpr2,Map2k1,Hcls1,Pdk3,Notch2,Rgcc,Egr1,Pmepa1,Gdf15,Dusp4,Ednrb,Ppp1r15a,Samsn1,Rcan1,Spred3,Gadd45b,Il12b,Agrn,Txn1,Il1rn,Ubash3b,Nlrc5,Dusp6,Kdr,Kitl,Mdfic,Cx3cl1,Ifna6,Nck1,Myd88,Met,Acvrl1,Cdkn1a,Sdc4,Fcgr2b,Tlr3,Ikbkg,Ifnar1,Casp3,Ppp2r5a,Pcx,Tnfrsf14,Cdk5r1,Psmd10,Prkce,Ccnd1,Mlkl,Pdgfc,Ifna1,Trib3,Ppp2r3a,Il1b,Il6,Hif1a,Itga5,Acvr1b,Dusp1,Ccnd2,Cflar,Ppp6r1,Lox,Dusp8,Mid1,Grk3,Thbs1,Plek,Prnp,Bmp2,Prkar2b,Dnaja1,Sema4c,Edn1,Stap1,Nod2,Mtcp1,Fas,Lrp8,Gadd45g,Irak3,Atp2b4,Ptger4,Plpp3,Bst1,Cenpe,Adora2a,Phlpp1,Hdac1,Irf1,Cx3cr1,Map2k4,Ppp1r15b,Acvr1,Plaur,Marco,Tlr2,Pim1,Irak2,Il18,Zc3h12a,Pid1,Notch1,Rhoh,Spred1,Nek6,Ifna5,Traf2,Irgm2,Ifna4,Stk40,Lrp4,Ripk2,Mul1,Parp9,Mvp,Gbp4,Nos2,Tab2,Map4k4,Csf3,Gcnt2,Ccne1,Ptprj,Ldlr,Igf1r,Cd40,Rbl1,Fgr,Vrk2,Map3k6,Phip,Wars,Nox1,Kat2b,Irs2,Nod1,Cdkn2d,Ifnb1,Uchl1,Icam1,Ccl5,Rabgef1,Aida,Actb,Malt1,C3,Cd74,Fabp3,Tlr1,Syk,Tpx2,Ccl4,Fzd1,Jun,Il1a,Ccl3,Daxx,Mapkbp1,Tnf,Prdx1,Pik3r5,Angpt1,Pml,Ccr1,Atf3,Rasgrp1,Ccnj,Ccl12,Sqstm1,Lmo4,Htr2b,Tnip1,Osm,Cav1,Lyn,Clcf1,Myadm,Ahr,Plcl2,Ccl22,Mmp9,Sirt1,Ier3,Lgals9,Hhex,Pik3r6,Cd80,Atm,Acsl1,Higd1a,Ksr1,Mmd,Ptgs2,Spn,Fam72a,Hsph1,Rapgef2,Dusp5,Fam129a,Adora2b,Dusp2,Ppp2r2a,Rap2c,Marf1 |
| 1.346e-41 | -94.11 | cell part | cellular component | GO:0044464 | 15725 | 1261 | 20747 | 1409 |
Plod2,Wars,Rhbdf2,Marf1,Grk3,Rhou,Casp3,Oas2,Vcpip1,Nt5c3,Phlda1,Ppp1r15a,Tle3,Dmxl2,Slc2a6,Dcp2,Fam111a,Cx3cr1,Flrt3,Klhl25,Psmb6,Ppp6r1,Ifi214,Map3k8,Tspan3,Mdn1,Fignl2,Klf8,Clec4d,Cdyl2,Junb,H2-T22,Pde4b,Arf4,Orai2,Trim14,Xrn1,Mark2,Nectin2,Stap1,Noct,Sh3bgrl2,Zfp800,Ifit3,Jmjd6,Nectin4,Mtmr14,Mthfd2,Plekha5,Cmklr1,Slc16a3,P2ry14,Hdc,Cd14,Cldnd1,Rgcc,Ifi204,Bcorl1,Gbp9,Slc29a3,Samsn1,Znrf1,Tnfrsf14,Acod1,Slco3a1,Hmgn3,Spsb1,Atp2b4,Abr,Radx,Rab11fip1,Kmt5a,Gk,Fam20c,Chic2,Dmwd,Maff,Nr3c1,Nfkbiz,Marco,Ier3,Slfn5,Gpsm2,Asah2,Ifit3b,Il13ra1,Asap3,Crbn,P2ry13,Map2k4,Ccnj,Prpf4,Lpar1,Pdk3,Cd302,Ccl2,Hsd17b7,Mx2,9130023H24Rik,Dcbld2,Adgrl2,Kif5c,Hdac1,F10,Kremen1,Slc25a12,Tyk2,Rap2c,Siglece,Traf2,Slc28a2,Snx10,Lacc1,Il12rb1,Rgs3,Ppfibp2,Ppfia3,Ociad1,Cycs,Itgb8,Tmeff1,Plat,Rnd3,Cnn2,Pgs1,Mecp2,Ifi209,Stoml1,Thbs1,Nfil3,Pdpn,Mov10,Tnks1bp1,Arid5a,Zswim4,Il15ra,Gadd45b,Sema4a,Gadd45g,Lipg,Rab32,Sgcb,Mtcp1,Myc,Map4k4,Il18,Phyh,Plod3,Stxbp3,Ifi207,Usb1,Rnf14,Ciapin1,Mppe1,Ddx58,Serpinb2,Slc30a1,H3f3b,Oas3,Itga5,Cnn3,Trim36,Sinhcaf,Ldha,Dnaja2,Slamf7,Pbx1,Rhoc,Ccne1,Socs3,Abcc5,Rcn1,Slc15a3,Mtfr2,Enpp4,Rab9,Cdc42ep2,H2-Aa,Prdm1,Nfxl1,Tnfsf10,Arl5c,S100a8,Spire1,Tmtc2,Ezr,Vezt,Tiparp,Lcp2,Milr1,Scimp,Nck1,Psat1,Reps1,Rab10,Ikbke,Adap2,Mcmbp,Adora2a,Rfx5,Cd274,Itgal,Agpat4,Trim13,Sass6,Ppp2r3a,Nat2,Rims3,Kitl,Pgap2,Plekhf2,Etv6,Msr1,Tgs1,Ppp1r12b,Tut7,Acvr1b,Kat2b,Mfap3l,Rsad2,Cep85l,Cx3cl1,Irgm1,Nod2,Chd9,H2-T10,Nfkbia,Dock4,Plekhn1,Rab21,Rars,Syk,Ripk2,Inhba,Zbtb5,Flt1,Caml,Prkx,Abcc1,Slc16a1,Azi2,Tap1,Gclc,Adrb2,Pstpip2,Slc25a25,Htra1,Tpm4,Sipa1l1,Hcar2,Gem,Phf11d,Gbp7,Hmox1,Stat1,Sgk3,Ap3b1,Stat4,Ext1,Pla2g4a,Lrp4,Ptch1,Nfkbie,Procr,Nek6,Med21,Lnpep,Ptgir,Grina,Rnaset2b,Sdc4,Sec24b,Lyn,Daxx,Gpd2,Isg15,Rasgrp1,Crlf3,Trim34a,Mcoln2,Dusp16,S1pr2,Hvcn1,Ncoa5,Aida,Isg20,Anp32a,Rsbn1,Irgm2,Gpr18,Plekha2,Nrp2,Foxp4,Ptafr,Whamm,Xcr1,Dock10,Gsap,Socs1,Ifi213,Ehd1,St3gal1,Tor3a,Perm1,Psme1,Mitd1,Fzd5,Cacybp,Pim2,Vcam1,Hat1,Oas1g,Arl4a,Btg2,Il4ra,Tapbp,Kcnj2,Bcl6,Gm5431,Esd,Fos,Tspo,Lox,Tasor2,Pml,Kdm5b,Swap70,Pdgfc,Pou2f2,Casp7,Sele,Ccr3,Cop1,Casp2,Dtnb,Rnf31,Etnk1,Cdyl,Spint2,Uba7,Klf2,P4ha2,Noc4l,Jun,Fpr2,Zeb1,Cyth3,Lif,Ccdc86,Adora2b,Parp12,Ikzf1,H2-Ab1,Phf11a,Fcho2,Ifnar1,Phactr4,Bfar,Dusp1,Phf11b,Olfr56,Kdm6b,Stk40,Ifit1,Nox1,Me1,Nmral1,Nr4a1,Rbms1,Shisa3,Rnf19a,Egr1,Nkiras1,Sap30,Egln3,Txnrd1,H2-Eb1,Smpdl3b,Daam1,Ntng2,Zfp40,Tma16,Tbc1d1,Igf1r,Tagln,1600014C10Rik,Mlkl,Hsph1,Slc13a3,Top3a,Ahsa1,Pdgfb,Myo10,Lad1,Ccr1,Rab19,Bbx,Bambi,Ubr4,Lmo4,Zc3h12a,Jarid2,Parp14,Acsl5,Oas1b,Lrch1,Axl,Tha1,Tpx2,Ier2,Pik3r5,A530064D06Rik,Ifit1bl2,Gfi1,Pdgfrb,Atf3,Psip1,Etv3,Cd40,Spata13,Hhex,Dhrs9,Socs7,Cdkn1a,Ak4,Plcl2,Sde2,Gna15,Tal2,Nfkbid,Alas1,Flnb,Ebi3,Scn1b,Hspa1b,Slc39a13,Lratd2,Nes,Pcgf5,Ifitm1,Stra6l,Sbds,Treml4,Psmb10,Irf4,Dnajb4,Nampt,Traf1,Ubash3b,Slc4a7,Xaf1,Cited2,Plpp1,Tra2a,Ddx4,Irf7,Ly6a,Aim2,Rhoh,Tpst1,Sla,F11r,Extl2,Atp6v1d,Ddx60,Osbpl3,Mapkapk2,Zfp36,Cers6,Ifi208,Vcan,Serpinb9,Coa5,Ddit4,Lcn2,Ifi203,Vrk2,Trim56,Pikfyve,Htr2a,Pid1,H2-Q7,Gm4841,9930111J21Rik1,Dennd6b,Batf2,Psd,Tlk2,Ifi35,Pdzd11,Calcrl,Pf4,Mxd1,Cd200,Tap2,Carhsp1,Cd86,Srxn1,Trim21,Parp10,Themis2,Pik3r6,Ell2,Hivep3,Zfp319,Pttg1,Tnfsf9,Uchl1,St3gal6,Dennd2a,Edn1,Tent2,Plaat3,Rnf114,Dek,Dpy19l1,Cenpe,Palld,Cdkn2d,Hcls1,Agrn,Ccnd2,Zup1,Acvr1,Cd82,Serpina3g,Psma6,P2ry2,Ep400,Pik3cd,Fndc3a,H2-M2,Mt2,Fpr1,Kif3c,Xkr8,Trim12a,Ppp2r2a,Tnf,Tnfaip3,Ccrl2,Nr4a3,Lipe,H60b,Klf7,Ctla2a,Mdm2,Gbgt1,Usp12,Atp10a,Rilpl1,Cd55,Ppp2r1b,Nfkbib,Hck,Il12b,Itpkc,Shfl,Olr1,Dgka,Jag1,Spic,Rel,Bst1,Stat2,4930453N24Rik,Eif4g2,Stat5a,Phlpp1,Cd164,Ranbp2,Gbp2b,Samd9l,Psmd10,Slc7a2,Pnp2,Tor1aip1,Ptk2,Polr2g,Nfkb2,Rcan1,Dach1,Adam19,Herc3,Fgr,Mtdh,Cxcl10,Cacna1d,Rnf139,Dusp4,Tuba4a,Atp11a,Golga3,Ythdf1,Hivep2,Ifih1,Clec2d,Ets2,Rnf145,Hsd17b12,Aldh1b1,Notch2,Ptger4,Dram1,Ahrr,Serpinb9b,Trip10,Dcun1d3,Nos2,Gclm,Ero1l,Usp25,Degs2,Filip1l,Gng11,Dhx58,Rcl1,Kif9,F830016B08Rik,Tnfsf14,Dr1,Selenow,Ptpn2,Cdk5r1,Slfn1,Spry2,Gys1,Slc25a37,Csrnp1,Slc7a5,Trib3,Cnp,Chmp4b,Dnase1l3,Wdr43,Armcx6,Mpp7,Ifi47,Pim3,Rtn2,Clic4,Kcna3,Rapgef5,Clec5a,Il15,Mocs1,Sdc2,Sirt1,Syne2,Dnaja1,Bnip3,Nlrp3,Odc1,Tlr3,Eya4,Angpt1,Mmp25,St3gal5,Keap1,G3bp2,Src,Lrch3,Gsr,Dync1h1,Rgs1,Dyrk2,Nod1,Spn,Prkar2b,Gng12,Parp11,Upp1,Tcf4,Myo1b,Dcp1a,Irf8,Mefv,Phf11c,Maml2,Abtb2,Tmem123,Asf1a,Gdf15,Plau,Ikbkg,B4galt4,Atm,Dgkh,Eno1,Plekha4,Prdx1,Mtus1,Myadm,Dtx2,Gng4,Vps54,Fbxo4,Cutc,Aftph,Slc39a14,Fcgr2b,Pilrb1,Mafg,Casz1,Sco1,Pde3b,Mul1,Ifit2,Plaur,Stau1,Gnb4,Tnfsf4,Gypc,Trip13,Il1b,Itgav,Tulp3,Mthfr,Ift22,Phf6,Errfi1,Pcx,Tet2,Smg7,Bcl2a1a,Homer1,Zfp945,Sema4c,Nr1h3,Pcdh7,Ppp2r5a,Irak3,Trim26,D1Ertd622e,Ric1,C3,Slc12a9,Clmp,Crkl,Cd38,Hlx,Rnf34,Ogfr,Zyx,Tmsb10,Dst,Hk3,Ubtd2,Cep350,Dnaaf3,Peli1,Ppp4r2,Egr3,Card6,Ift57,Pde1b,Nlgn2,Taf4b,Myd88,Piezo1,Itpr1,Hmgcs1,Mosmo,Fam53c,Bmp2,Eef1e1,Igf2bp2,Mndal,Cacnb3,Ube2l6,Cmpk2,Cebpd,Gramd1a,Il18rap,Prag1,Gpr68,Csf3r,Txn1,Higd1a,Sp140,Hmga2,Pou3f1,Lap3,Pfkfb3,Gm4951,Pnpt1,Cst7,Tmem178,Cgas,Gja1,Dusp8,Cd74,Zfp513,Cd300e,Kdm4a,Tmem176b,Cp,Idi1,H2-Q4,Plac8,Cflar,Ly6c2,Psme2,Bcl9,Ktn1,Irak2,Tlr1,Car13,Ksr1,Plekhg1,Trmt1l,Actb,Mrpl52,Mdfic,Casp8,Fam241a,Sgms2,Slc31a1,Pgm1,Prnp,Eif2ak2,Pmaip1,Ust,Tmc3,Hmga1,Arhgef3,Sema3c,St3gal3,Plk2,Plpp3,Tlr9,Rbms2,Rras2,Hk1,Stat3,Tarm1,Ms4a4b,Dck,Pvr,Pde5a,Rbbp8,Ago3,Csrp1,Cav1,Atp13a1,Mmd,Lnpk,Ppm1k,Gpr85,Slc44a1,Pla2g7,Cd200r4,Katna1,Wdfy1,Mid1,Klra2,Mier3,Sesn3,Rbpms,Cd80,Tdrd7,Fmnl2,Vasp,Uaca,Igsf9,Prpf38a,Lrp8,Tent4a,Sat1,Spen,Tank,Plagl1,Stx6,Lztfl1,Pgk1,Adar,Prdx5,Flrt2,Mt1,Timeless,Cdc42ep4,Gpc1,Tomm70a,Gpr132,Hk2,Trim30a,Apba1,Rapgef2,Cnot4,Mmp14,Herc6,Znrf3,Adgrg6,Itga4,Spred1,Ggct,Cemip2,Lhx2,Cyfip1,Ralgds,Bcl2l11,Zhx2,Morc3,Ppp1r14b,P2ry12,Clcn5,Rabgef1,Gpr35,Kdr,Ncoa7,Carmil1,Dbnl,Calhm6,Sod2,Dusp2,Ppa1,Serp1,Slfn9,Sdc1,Arhgap26,Ap3m2,Micall2,Ifi44,Smc5,Minpp1,Naa25,Hopx,Treml2,Csf1,Birc2,Antxr1,Oas1a,Sell,Resf1,Stx11,Dse,Sh3bp4,Arl5b,Batf,Pfkl,Agtrap,Cxcl14,Mvp,Gm12185,Bcl2a1b,Frmd4a,Clcn7,Rbl1,Magohb,Yju2,Ptges,Ampd3,Ldlr,Tmod3,Irf1,Oasl2,Dync1i2,Lgals9,Ptprj,Ankrd17,Psmb9,Ccdc88b,Bcor,Ripk3,Raet1e,Arg2,Wdr59,Rab20,Snn,Cpd,Mafk,Vasn,AA467197,Sp100,Ctsc,Etv5,Ctu1,Gpr141,Mx1,Slfn8,Il1a,Stip1,Lrrc25,B430306N03Rik,Tmem219,Ch25h,Kctd12,Snapc1,Brwd3,Ciita,Fam72a,Svbp,Eno2,Trim12c,Nxf1,Dtx3l,Gbp3,Sp110,Tnfrsf1b,Egr2,Prkce,Jak2,Znfx1,Rrbp1,Rrs1,Rnd1,Hspa2,Plagl2,Tab2,Irs2,Fam129a,Mycl,Casp4,Marcksl1,Gch1,Klrk1,Sik3,Slc37a3,Igsf8,Map2k1,Zfp281,Casp1,Rnf19b,Cox17,Gm5150,Rubcnl,P4ha1,Scyl2,Spred3,Rin2,Fnbp1l,Rmdn3,Optn,Tgtp1,Tapbpl,Tpi1,Kpna3,Fabp3,Mcm9,Aff1,Glipr2,Plek,Zc3hav1,Adgre4,Nlrc4,Apaf1,Fam162a,Fosb,Phldb1,B3gnt5,Ccng2,Cish,Snx2,Parp3,Rab3ip,Ube2e1,Adhfe1,Plk3,Cenpj,Samhd1,Hap1,Fcgr4,Irf2,Psmb8,Jdp2,Cept1,Fubp1,Nsd3,Arrdc4,Gbp8,Bcl2a1d,Il6,Il4i1,Klf3,Fas,Met,Tifa,Rai14,Rap1gap2,Phgdh,Arid5b,Tgtp2,Nmi,Larp1,Tfec,Gsdmd,Fcgr1,Phlpp2,Trib1,Fabp7,Acvrl1,Dusp5,Intu,Klf6,Brd2,Ahr,Parp9,Gbp2,Tcea1,Nqo1,Pdlim7,Sqstm1,Ifi211,Ifrd1,Clic5,Mapkbp1,Iigp1,Tmem67,Acp5,Stxbp1,H2-T24,Cpeb4,Slc7a8,Dusp14,Slc39a4,Glrx,H2-Q6,Akt3,Slc49a4,Notch1,Rpgrip1l,Slc7a11,Phip,Abcc4,Serpinb6b,Gca,Setdb2,Prokr1,Plscr1,Tlr6,Lpcat2,Cd300lf,Slc30a4,Hif1a,Cd69,Smox,Tnfaip2,Pigv,Ass1,Dennd1b,Rictor,Hspa1a,Slc31a2,Pkp4,Oasl1,Hilpda,Zcchc2,Gpr84,Pdss1,Rnf24,Gcnt2,Med13,Sertad3,Relb,Ddhd1,Helz2,Icam1,Armc8,Ifi205,Rnaset2a,Cox18,Nfkbil1,Aoah,Ascc3,Ccnd1,4932438A13Rik,Stard7,Tbc1d13,Slc48a1,Ppp1r15b,Mthfd1l,Gsta3,Tnfsf15,Fzd1,Abcb1a,Inpp5b,Triobp,Il2rg,Gtpbp2,Acsl1,Fut8,Acpp,Sav1,Cd180,Asns,Traf5,Ankib1,Tshz1,Rnf135,Cxcl9,Evl,Ly75,Mcm10,Zbp1,Riox2,N4bp1,Rhoq,Rtp4,Il1rn,Arid4a,Lrrc8c,Psd4,Mmp13,Rgs14,Tgfbi,Fscn1,Rhof,Gmppb,Frmd6,Pim1,Kmo,Nlrc5,Zmynd15,Pmepa1,Itga9,Usp18,Rtn1,Mgat1,Cysltr2,Ccl5,Usp31,Nfkb1,Nupr1,Arel1,Igtp,Malt1,Mamld1,Htr2b,Sec24a,Apobec3,Atp11b,Slc25a22,Cd83,Prdm9,Tlr2,Hinfp,Sphk1,Ifit1bl1,Dusp6,Icosl,Rac3,Chst11,Marcks,Serpine1,Max,Rffl,Ednrb,Acp2,Srgn,Tor1aip2,Mcm6,Aebp2,Cd34,Birc3,Slc2a1,Fchsd2,Ptgs2,Slc9a1,Hp,Tnip1,Dnajb2 |
| 1.669e-41 | -93.89 | cell | cellular component | GO:0005623 | 15729 | 1261 | 20747 | 1409 |
Tet2,Smg7,Tulp3,Itgav,Mthfr,Phf6,Ift22,Pcx,Errfi1,Trip13,Gypc,Il1b,Plaur,Stau1,Gnb4,Tnfsf4,Sco1,Pde3b,Ifit2,Mul1,Mafg,Casz1,Slc39a14,Aftph,Pilrb1,Fcgr2b,Cutc,Ric1,C3,Slc12a9,Clmp,Trim26,D1Ertd622e,Irak3,Ppp2r5a,Nr1h3,Pcdh7,Homer1,Zfp945,Sema4c,Bcl2a1a,Egr3,Card6,Ift57,Peli1,Ppp4r2,Dnaaf3,Cep350,Ubtd2,Hk3,Dst,Ogfr,Zyx,Tmsb10,Rnf34,Hlx,Cd38,Crkl,Csf3r,Higd1a,Txn1,Sp140,Il18rap,Prag1,Gpr68,Cebpd,Gramd1a,Mndal,Cacnb3,Ube2l6,Cmpk2,Igf2bp2,Itpr1,Hmgcs1,Mosmo,Fam53c,Eef1e1,Bmp2,Nlgn2,Pde1b,Taf4b,Piezo1,Myd88,Armcx6,Mpp7,Slc7a5,Trib3,Cnp,Chmp4b,Dnase1l3,Wdr43,Gys1,Csrnp1,Slc25a37,Slfn1,Cdk5r1,Spry2,Dr1,Selenow,Ptpn2,Kif9,F830016B08Rik,Tnfsf14,Dhx58,Rcl1,Degs2,Filip1l,Gng11,Odc1,Dnaja1,Bnip3,Nlrp3,Sirt1,Sdc2,Syne2,Mocs1,Il15,Rapgef5,Clec5a,Rtn2,Clic4,Kcna3,Ifi47,Pim3,Myo1b,Dcp1a,Prkar2b,Gng12,Upp1,Parp11,Tcf4,Nod1,Spn,Dync1h1,Rgs1,Dyrk2,G3bp2,Gsr,Src,Lrch3,Mmp25,St3gal5,Keap1,Angpt1,Eya4,Tlr3,Gng4,Fbxo4,Vps54,Dtx2,Prdx1,Mtus1,Myadm,B4galt4,Atm,Dgkh,Plekha4,Eno1,Ikbkg,Asf1a,Gdf15,Plau,Maml2,Tmem123,Abtb2,Irf8,Mefv,Phf11c,Spen,Sat1,Tank,Plagl1,Uaca,Vasp,Igsf9,Prpf38a,Tent4a,Lrp8,Tdrd7,Fmnl2,Rbpms,Cd80,Wdfy1,Mid1,Klra2,Sesn3,Mier3,Katna1,Cd200r4,Pla2g7,Cyfip1,Ralgds,Cemip2,Lhx2,Adgrg6,Itga4,Ggct,Spred1,Cnot4,Mmp14,Znrf3,Herc6,Rapgef2,Apba1,Hk2,Gpr132,Trim30a,Adar,Prdx5,Mt1,Flrt2,Timeless,Cdc42ep4,Gpc1,Tomm70a,Lztfl1,Stx6,Pgk1,Calhm6,Carmil1,Dbnl,Kdr,Ncoa7,Clcn5,Rabgef1,Gpr35,P2ry12,Morc3,Zhx2,Ppp1r14b,Bcl2l11,Sell,Csf1,Birc2,Antxr1,Oas1a,Hopx,Treml2,Micall2,Ifi44,Smc5,Minpp1,Naa25,Arhgap26,Ap3m2,Slfn9,Sdc1,Dusp2,Serp1,Ppa1,Sod2,H2-Q4,Plac8,Idi1,Cp,Dusp8,Cd74,Zfp513,Cd300e,Kdm4a,Tmem176b,Gja1,Cst7,Cgas,Tmem178,Lap3,Pou3f1,Gm4951,Pfkfb3,Pnpt1,Hmga2,Slc31a1,Sgms2,Fam241a,Trmt1l,Actb,Mrpl52,Mdfic,Casp8,Ksr1,Plekhg1,Irak2,Ktn1,Bcl9,Car13,Tlr1,Cflar,Ly6c2,Psme2,Plpp3,Tlr9,Rbms2,Plk2,St3gal3,Sema3c,Arhgef3,Tmc3,Ust,Hmga1,Prnp,Eif2ak2,Pmaip1,Pgm1,Ppm1k,Lnpk,Gpr85,Slc44a1,Mmd,Atp13a1,Csrp1,Cav1,Rbbp8,Pde5a,Ago3,Tarm1,Ms4a4b,Dck,Pvr,Stat3,Hk1,Rras2,Spred3,Rubcnl,Scyl2,P4ha1,Gm5150,Cox17,Rnf19b,Map2k1,Zfp281,Casp1,Klrk1,Igsf8,Sik3,Slc37a3,Fosb,Phldb1,Fam162a,Adgre4,Nlrc4,Apaf1,Aff1,Glipr2,Zc3hav1,Plek,Fabp3,Mcm9,Tpi1,Kpna3,Tapbpl,Rin2,Fnbp1l,Tgtp1,Rmdn3,Optn,Arrdc4,Gbp8,Bcl2a1d,Il6,Psmb8,Jdp2,Cept1,Fubp1,Nsd3,Samhd1,Cenpj,Hap1,Fcgr4,Irf2,Rab3ip,Ube2e1,Adhfe1,Plk3,Parp3,B3gnt5,Ccng2,Snx2,Cish,Intu,Brd2,Klf6,Dusp5,Trib1,Fabp7,Acvrl1,Phlpp2,Larp1,Tfec,Gsdmd,Fcgr1,Phgdh,Arid5b,Nmi,Tgtp2,Tifa,Rai14,Rap1gap2,Il4i1,Met,Klf3,Fas,Rbl1,Magohb,Yju2,Ptges,Frmd4a,Clcn7,Bcl2a1b,Gm12185,Mvp,Pfkl,Agtrap,Cxcl14,Batf,Arl5b,Stx11,Resf1,Dse,Sh3bp4,Cpd,Mafk,Vasn,Snn,Wdr59,Arg2,Rab20,Ccdc88b,Bcor,Ripk3,Raet1e,Ankrd17,Ptprj,Lgals9,Psmb9,Irf1,Tmod3,Dync1i2,Oasl2,Ampd3,Ldlr,Brwd3,Snapc1,Kctd12,Lrrc25,B430306N03Rik,Tmem219,Ch25h,Il1a,Stip1,Slfn8,Etv5,Ctu1,Gpr141,Mx1,AA467197,Ctsc,Sp100,Marcksl1,Casp4,Gch1,Plagl2,Irs2,Tab2,Fam129a,Mycl,Hspa2,Rrs1,Rnd1,Jak2,Rrbp1,Znfx1,Gbp3,Sp110,Tnfrsf1b,Egr2,Prkce,Eno2,Trim12c,Nxf1,Dtx3l,Svbp,Ciita,Fam72a,Ly75,Mcm10,Zbp1,Riox2,Cxcl9,Evl,Tshz1,Rnf135,Sav1,Cd180,Acpp,Asns,Traf5,Ankib1,Acsl1,Fut8,Triobp,Il2rg,Gtpbp2,Abcb1a,Inpp5b,Zmynd15,Pmepa1,Nlrc5,Pim1,Kmo,Gmppb,Frmd6,Tgfbi,Fscn1,Rhof,Lrrc8c,Mmp13,Rgs14,Psd4,N4bp1,Rhoq,Il1rn,Rtp4,Arid4a,Dusp6,Chst11,Rac3,Marcks,Icosl,Serpine1,Ifit1bl1,Sphk1,Tlr2,Hinfp,Slc25a22,Cd83,Prdm9,Sec24a,Apobec3,Atp11b,Mamld1,Malt1,Htr2b,Usp31,Nfkb1,Nupr1,Arel1,Igtp,Usp18,Itga9,Rtn1,Cysltr2,Mgat1,Ccl5,Tnip1,Dnajb2,Hp,Ptgs2,Slc9a1,Birc3,Slc2a1,Fchsd2,Mcm6,Tor1aip2,Aebp2,Cd34,Acp2,Srgn,Max,Ednrb,Rffl,Iigp1,Tmem67,Acp5,Clic5,Mapkbp1,Ifrd1,Ifi211,Sqstm1,Nqo1,Pdlim7,Gbp2,Tcea1,Ahr,Parp9,Plscr1,Tlr6,Setdb2,Prokr1,Phip,Abcc4,Serpinb6b,Gca,Notch1,Slc49a4,Rpgrip1l,Slc7a11,Slc39a4,Glrx,H2-Q6,Akt3,Dusp14,H2-T24,Cpeb4,Stxbp1,Slc7a8,Gcnt2,Med13,Gpr84,Pdss1,Rnf24,Hilpda,Zcchc2,Slc31a2,Hspa1a,Pkp4,Oasl1,Ass1,Dennd1b,Rictor,Smox,Tnfaip2,Pigv,Slc30a4,Cd300lf,Hif1a,Cd69,Lpcat2,Fzd1,Mthfd1l,Gsta3,Tnfsf15,Tbc1d13,Slc48a1,Ppp1r15b,4932438A13Rik,Stard7,Ccnd1,Cox18,Nfkbil1,Aoah,Ascc3,Helz2,Icam1,Armc8,Ifi205,Rnaset2a,Sertad3,Relb,Ddhd1,Mx2,Cd302,Hsd17b7,Ccl2,Prpf4,Lpar1,Pdk3,Crbn,Map2k4,P2ry13,Ccnj,Asah2,Ifit3b,Il13ra1,Asap3,Ier3,Gpsm2,Slfn5,Maff,Nr3c1,Nfkbiz,Marco,Dmwd,Slc28a2,Traf2,Rap2c,Siglece,Slc25a12,Tyk2,Kif5c,F10,Hdac1,Kremen1,Adgrl2,9130023H24Rik,Dcbld2,Ifi209,Stoml1,Rnd3,Pgs1,Cnn2,Mecp2,Plat,Tmeff1,Ociad1,Cycs,Itgb8,Rgs3,Ppfibp2,Ppfia3,Lacc1,Il12rb1,Snx10,Stxbp3,Ifi207,Usb1,Rnf14,Ciapin1,Phyh,Plod3,Map4k4,Myc,Il18,Mtcp1,Gadd45g,Lipg,Sgcb,Rab32,Il15ra,Gadd45b,Sema4a,Mov10,Tnks1bp1,Zswim4,Arid5a,Pdpn,Thbs1,Nfil3,Tle3,Dmxl2,Slc2a6,Dcp2,Ppp1r15a,Nt5c3,Phlda1,Casp3,Oas2,Vcpip1,Wars,Plod2,Rhbdf2,Marf1,Grk3,Rhou,Junb,H2-T22,Cdyl2,Klf8,Clec4d,Fignl2,Mdn1,Ppp6r1,Map3k8,Ifi214,Tspan3,Psmb6,Fam111a,Klhl25,Flrt3,Cx3cr1,Cldnd1,Cd14,Slc16a3,Mthfd2,Plekha5,Cmklr1,P2ry14,Hdc,Mtmr14,Nectin4,Jmjd6,Nectin2,Noct,Stap1,Zfp800,Sh3bgrl2,Ifit3,Mark2,Xrn1,Pde4b,Orai2,Arf4,Trim14,Fam20c,Chic2,Kmt5a,Gk,Atp2b4,Abr,Radx,Rab11fip1,Slco3a1,Hmgn3,Spsb1,Znrf1,Samsn1,Tnfrsf14,Acod1,Ifi204,Gbp9,Slc29a3,Bcorl1,Rgcc,Sipa1l1,Hcar2,Gem,Htra1,Slc25a25,Tpm4,Pstpip2,Gclc,Adrb2,Tap1,Azi2,Abcc1,Prkx,Slc16a1,Syk,Ripk2,Inhba,Flt1,Caml,Zbtb5,Rars,Trim34a,Mcoln2,Rasgrp1,Crlf3,Grina,Rnaset2b,Sec24b,Sdc4,Daxx,Lyn,Gpd2,Isg15,Ptch1,Nfkbie,Procr,Nek6,Med21,Ptgir,Lnpep,Lrp4,Sgk3,Stat4,Ap3b1,Ext1,Pla2g4a,Stat1,Phf11d,Gbp7,Hmox1,Foxp4,Ptafr,Whamm,Nrp2,Plekha2,Irgm2,Gpr18,Isg20,Anp32a,Rsbn1,Hvcn1,Ncoa5,Aida,S1pr2,Dusp16,Tapbp,Kcnj2,Bcl6,Arl4a,Btg2,Il4ra,Cacybp,Pim2,Vcam1,Hat1,Oas1g,Mitd1,Fzd5,Perm1,Psme1,Ehd1,Ifi213,St3gal1,Tor3a,Gsap,Socs1,Xcr1,Dock10,Socs3,Abcc5,Rcn1,Ccne1,Slamf7,Pbx1,Dnaja2,Rhoc,Sinhcaf,Ldha,Cnn3,Trim36,Itga5,Serpinb2,Slc30a1,H3f3b,Oas3,Mppe1,Ddx58,Tmtc2,Spire1,Arl5c,S100a8,Prdm1,Tnfsf10,Nfxl1,H2-Aa,Slc15a3,Mtfr2,Enpp4,Rab9,Cdc42ep2,Adora2a,Rfx5,Cd274,Agpat4,Itgal,Adap2,Ikbke,Mcmbp,Psat1,Reps1,Rab10,Nck1,Scimp,Vezt,Tiparp,Lcp2,Milr1,Ezr,H2-T10,Nfkbia,Dock4,Plekhn1,Rab21,Rsad2,Cep85l,Cx3cl1,Irgm1,Nod2,Chd9,Kat2b,Mfap3l,Ppp1r12b,Acvr1b,Tut7,Msr1,Tgs1,Plekhf2,Etv6,Kitl,Pgap2,Trim13,Sass6,Ppp2r3a,Nat2,Rims3,Tpx2,Ier2,Lrch1,Axl,Tha1,Parp14,Acsl5,Oas1b,Ubr4,Lmo4,Zc3h12a,Jarid2,Bbx,Bambi,Rab19,Myo10,Lad1,Ccr1,Ahsa1,Pdgfb,Nfkbid,Alas1,Gna15,Tal2,Ak4,Plcl2,Sde2,Dhrs9,Socs7,Cdkn1a,Spata13,Hhex,Psip1,Etv3,Cd40,Ifit1bl2,Gfi1,Pdgfrb,Atf3,Pik3r5,A530064D06Rik,Dnajb4,Irf4,Nampt,Traf1,Sbds,Stra6l,Treml4,Psmb10,Ifitm1,Nes,Pcgf5,Slc39a13,Lratd2,Hspa1b,Scn1b,Flnb,Ebi3,Ddx60,Osbpl3,Mapkapk2,Atp6v1d,Extl2,Tpst1,Rhoh,Sla,F11r,Ly6a,Aim2,Ddx4,Irf7,Plpp1,Tra2a,Ubash3b,Slc4a7,Xaf1,Cited2,Casp2,Rnf31,Dtnb,Sele,Ccr3,Cop1,Casp7,Kdm5b,Swap70,Pdgfc,Pou2f2,Lox,Tspo,Tasor2,Pml,Esd,Fos,Gm5431,Adora2b,Ccdc86,Lif,Cyth3,Zeb1,Jun,Fpr2,P4ha2,Noc4l,Etnk1,Cdyl,Uba7,Spint2,Klf2,Nr4a1,Rbms1,Shisa3,Nmral1,Me1,Nox1,Ifit1,Olfr56,Kdm6b,Stk40,Dusp1,Phf11b,Phf11a,H2-Ab1,Fcho2,Bfar,Ifnar1,Phactr4,Parp12,Ikzf1,Slc13a3,Top3a,Hsph1,1600014C10Rik,Mlkl,Smpdl3b,Daam1,Ntng2,Zfp40,Tma16,Igf1r,Tbc1d1,Tagln,Egln3,Txnrd1,H2-Eb1,Sap30,Egr1,Nkiras1,Rnf19a,Atp10a,Usp12,Rilpl1,Mdm2,Gbgt1,Klf7,Ctla2a,Nr4a3,Lipe,H60b,Tnfaip3,Ccrl2,Ppp2r2a,Trim12a,Tnf,Kif3c,Xkr8,Ranbp2,Phlpp1,Cd164,Eif4g2,Stat5a,Bst1,Stat2,4930453N24Rik,Dgka,Jag1,Spic,Rel,Itpkc,Shfl,Olr1,Nfkbib,Hck,Il12b,Cd55,Ppp2r1b,Hivep2,Ythdf1,Ifih1,Clec2d,Tuba4a,Atp11a,Golga3,Cacna1d,Rnf139,Dusp4,Dach1,Rcan1,Adam19,Herc3,Fgr,Cxcl10,Mtdh,Psmd10,Ptk2,Pnp2,Tor1aip1,Slc7a2,Polr2g,Nfkb2,Gbp2b,Samd9l,Gclm,Nos2,Usp25,Ero1l,Serpinb9b,Trip10,Dcun1d3,Dram1,Ahrr,Notch2,Ptger4,Hsd17b12,Aldh1b1,Ets2,Rnf145,Cd200,Mxd1,Tlk2,Ifi35,Calcrl,Pdzd11,Pf4,9930111J21Rik1,Dennd6b,Batf2,Psd,Gm4841,Vrk2,Pikfyve,Trim56,H2-Q7,Pid1,Htr2a,Ddit4,Coa5,Lcn2,Ifi203,Zfp36,Ifi208,Vcan,Cers6,Serpinb9,Pttg1,Uchl1,Tnfsf9,Zfp319,Themis2,Pik3r6,Ell2,Hivep3,Parp10,Srxn1,Trim21,Carhsp1,Tap2,Cd86,Cdkn2d,Hcls1,Cenpe,Palld,Dpy19l1,Plaat3,Rnf114,Dek,Tent2,St3gal6,Edn1,Dennd2a,Fpr1,Fndc3a,H2-M2,Mt2,Ep400,Pik3cd,Psma6,P2ry2,Cd82,Serpina3g,Acvr1,Agrn,Ccnd2,Zup1 |
| 2.133e-41 | -93.65 | GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_DN | 167 | 78 | 15632 | 1249 |
Phf11b,Ifit2,Casp1,Ifnar1,Psmb9,Rbbp8,Oas3,Ifi44,Dhx58,Rsad2,Aim2,Usp18,Kmo,Ddx58,Dtx3l,Ifih1,Isg15,Trim12c,Gbp3,Ncoa7,Cd38,Rgl1,Ifit1bl2,Slc31a2,Ccr1,Card6,Gch1,Dusp6,Atp6v1d,Irf7,Ube2l6,Tlr1,Nmi,Wars,Parp12,Oas2,Herc6,Hmox1,Oas1g,Cxcl10,Il1rn,Tnfsf10,Fmnl2,Epsti1,Cmpk2,Sp110,Ifit1bl1,Plac8,Eif2ak2,Tet2,Parp14,Nat2,Rin2,Parp9,Samd9l,Ddx60,Rtp4,Adar,Pnpt1,Phf11a,Zbp1,Tap1,Phf11c,Ifit3,Lap3,Psme2,Plscr1,Oas1a,Xaf1,Tdrd7,Casp7,Oasl1,Stat1,Phf11d,Azi2,Ifit3b,Gbp2b,Vrk2 |
| 2.462e-41 | -93.51 | regulation of phosphorylation | biological process | GO:0042325 | 1557 | 253 | 20694 | 1406 |
Cenpe,Bst1,Plpp3,Ptger4,Atp2b4,Adora2a,Irf1,Phlpp1,Hdac1,Acvr1,Plaur,Ppp1r15b,Map2k4,Cx3cr1,Edn1,Stap1,Sema4c,Dnaja1,Prkar2b,Lrp8,Fas,Mtcp1,Nod2,Irak3,Gadd45g,Traf2,Ifna5,Nek6,Spred1,Tab2,Gbp4,Mvp,Mul1,Ripk2,Parp9,Lrp4,Stk40,Ifna4,Irgm2,Csf3,Gcnt2,Map4k4,Ptprj,Ccne1,Marco,Pim1,Tlr2,Zc3h12a,Il18,Irak2,Rhoh,Notch1,Pid1,Ccl4,Tpx2,Syk,Mapkbp1,Tnf,Il1a,Ccl3,Daxx,Jun,Fzd1,Angpt1,Pik3r5,Prdx1,Ccnj,Ccl12,Rasgrp1,Atf3,Ccr1,Pml,Nox1,Phip,Wars,Map3k6,Vrk2,Fgr,Rbl1,Cd40,Igf1r,Rabgef1,Ccl5,Icam1,Uchl1,Cdkn2d,Ifnb1,Nod1,Irs2,Kat2b,Malt1,Actb,Aida,Tlr1,Cd74,C3,Higd1a,Acsl1,Atm,Cd80,Ptgs2,Mmd,Ksr1,Fam129a,Dusp5,Fam72a,Rapgef2,Hsph1,Spn,Rap2c,Dusp2,Htr2b,Lmo4,Sqstm1,Myadm,Clcf1,Cav1,Lyn,Osm,Tnip1,Ier3,Sirt1,Mmp9,Ccl22,Plcl2,Pik3r6,Hhex,Lgals9,Rbpms,Ifna2,Socs3,Vegfc,Socs1,Slfn1,Ccl7,Eif2ak2,Map3k8,Glipr2,Ppp1r14b,Ccl2,Slamf8,Fcgr1,Tlr9,Adrb2,Ddit4,Birc3,Ezr,Parp14,Dusp16,Hspa2,S1pr2,Csf1,Nupr1,Il15,Spry2,Ccng2,Ptpn2,Fzd5,Pdgfrb,Myc,Pde5a,Ccl8,Htr2a,Ccl9,Ptk2,Flt1,Ak4,Pdgfb,Lif,Lpar1,Tnfsf15,Src,Stat3,Tnks1bp1,Hcls1,Map2k1,Fpr2,Stat2,Jak2,Tlr6,Errfi1,Sphk1,Crkl,Adar,Cysltr2,Ripk3,Trib1,Tnfaip3,Inhba,Pgk1,Rictor,Ranbp2,Scimp,Rgs14,Kdr,Dusp6,Nlrc5,Ubash3b,Cx3cl1,Mdfic,Kitl,Acvrl1,Met,Myd88,Nck1,Ifna6,Fcgr2b,Sdc4,Cdkn1a,Pmepa1,Egr1,Rgcc,Notch2,Samsn1,Ppp1r15a,Ednrb,Dusp4,Gdf15,Txn1,Il1rn,Il12b,Agrn,Spred3,Gadd45b,Ccnd2,Dusp1,Itga5,Acvr1b,Hif1a,Il6,Dusp8,Mid1,Lox,Cflar,Prnp,Thbs1,Grk3,Bmp2,Casp3,Ikbkg,Ifnar1,Tlr3,Ccnd1,Psmd10,Prkce,Cdk5r1,Tnfrsf14,Ppp2r5a,Pdgfc,Ifna1,Mlkl,Il1b,Trib3 |
| 2.525e-41 | -93.48 | regulation of protein modification process | biological process | GO:0031399 | 1822 | 280 | 20694 | 1406 |
Ccnd2,Dusp1,Acvr1b,Itga5,Il6,Kdm4a,Mid1,Dusp8,Lox,Ppp6r1,Cflar,Prnp,Fbxo4,Thbs1,Grk3,N4bp1,Bmp2,Casp3,Ikbkg,Ifnar1,Tlr3,Ccnd1,Cdk5r1,Psmd10,Prkce,Tnfrsf14,Ppp2r5a,Pdgfc,Ifna1,Mlkl,Il1b,Isg15,Ppp2r3a,Trib3,Kdr,Dusp6,Ubash3b,Cx3cl1,Mdfic,Kitl,Acvrl1,Met,Myd88,Nck1,Ifna6,Arid5a,Fcgr2b,Sdc4,Cdkn1a,Egr1,Pmepa1,Rgcc,Notch2,Ppp1r15a,Samsn1,Ednrb,Bcl6,Dusp4,Gdf15,Txn1,Il1rn,Agrn,Il12b,Gadd45b,Spred3,Rcan1,Flt1,Vcan,Pdgfb,Lif,Lpar1,Tnfsf15,Peli1,Src,Tnks1bp1,Hcls1,Map2k1,Fpr2,Stat2,Tlr6,Jak2,Bcor,Errfi1,Sphk1,Crkl,Adar,Cysltr2,Ripk3,Trib1,Tnfaip3,Inhba,Rictor,Swap70,Scimp,Rgs14,Rbpms,Ifna2,Socs3,Ppp2r1b,Mecp2,Vegfc,Phactr4,Dcun1d3,Socs1,Slfn1,Ccl7,Eif2ak2,Map3k8,Glipr2,Ppp1r14b,Ccl2,Fcgr1,Adrb2,Arrdc4,Tlr9,Ddit4,Birc3,Ezr,Mllt6,Parp14,Birc2,Dusp16,Hspa2,S1pr2,Nupr1,Csf1,Il15,Spry2,Ccng2,Dnajb2,Ptpn2,Fzd5,Pdgfrb,Pde5a,Ccl8,Htr2a,Ccl9,Ppp4r2,Ptk2,Higd1a,Acsl1,Atm,Cd80,Ptgs2,Ahrr,Mmd,Ksr1,Tank,Fam129a,Cdyl,Dusp5,Fam72a,Rapgef2,Hsph1,Spn,Rap2c,Dusp2,Ppp2r2a,Htr2b,Sqstm1,Myadm,Clcf1,Cav1,Lyn,Osm,Tnip1,Ncoa7,Mmp9,Sirt1,Plcl2,Ccl22,Pik3r6,Hhex,Lgals9,Ccl4,Tpx2,Syk,Tnf,Mapkbp1,Ccl3,Daxx,Il1a,Jun,Fzd1,Angpt1,Pik3r5,Prdx1,Ccnj,Caml,Ccl12,Rasgrp1,Parp10,Atf3,Ccr1,Pml,Phip,Wars,Nox1,Map3k6,Vrk2,Fgr,Cd40,Igf1r,Rabgef1,Ccl5,Icam1,Uchl1,Nod1,Cdkn2d,Ifnb1,Jdp2,Kat2b,Actb,Malt1,Aida,Tlr1,Gclc,Cd74,C3,Mthfr,Traf2,Ifna5,Nek6,Spred1,Tab2,Gbp4,Mvp,Mul1,Ripk2,Parp9,Lrp4,Ifna4,Stk40,Irgm2,Csf3,Gcnt2,Map4k4,Nmi,Ptprj,Ccne1,Jarid2,Marco,Pim1,Tlr2,Zc3h12a,Il18,Irak2,Notch1,Pid1,Gfi1,Cenpe,Bst1,Plpp3,Ptger4,Atp2b4,Adora2a,Tspo,Irf1,Phlpp1,Hdac1,Plaur,Acvr1,Ppp1r15b,Map2k4,Cx3cr1,Edn1,Stap1,Trim21,Sema4c,Dnaja1,Prkar2b,Lrp8,Nsd3,Fas,Mtcp1,Nod2,Dtx3l,Irak3,Svbp,Gadd45g |
| 6.515e-41 | -92.53 | regulation of biological process | biological process | GO:0050789 | 11457 | 1014 | 20694 | 1406 |
Tmem178,Usp25,Ripk2,Mul1,Tmod3,Wdfy1,Mvp,Rhbdf2,Trim26,Casp4,Casp1,Ccne1,Ifi203,Hap1,Dgka,Marcksl1,Foxp4,Marco,Crbn,H2-T22,Osgin2,Frmd4a,Gpr18,Ythdf1,Scarf1,Chmp4b,Slfn2,Plpp3,Fchsd2,Serpina3g,Irf1,Il10,Rab21,Dach1,Map2k4,Ppp1r15b,Irf2,Trip13,Edn1,Serpinb2,Frmd6,Hvcn1,Rubcnl,Fas,Pkp4,Svbp,Itga4,Irf4,Lnpep,Ccr3,Ptgir,Rhoc,Ogfr,Cyfip1,Ralgds,Oasl2,Ifit2,Ier2,Bcl9,Ifi213,Gna15,Ptgs2,Mier3,Tax1bp1,Rapgef2,Rap2c,Cd86,Marf1,Riox2,Samd9l,Acod1,Itpr1,F11r,Cav1,Slc31a2,Spire1,Cxcl11,Trim30a,Myadm,Arel1,Ccl22,Sirt1,Etv3,Cd83,Rnf135,Stxbp1,Tcf4,Pcgf5,Tnf,Plk3,Mapkbp1,Il27,Pilrb1,Mxd1,Angpt1,Ikzf1,Asah2,Acpp,Sertad3,Parp10,Taf4b,Rasgrp1,Ccl12,Rras2,Cd40,Rbl1,Mtdh,Nlgn2,Mycl,Dync1h1,Igf2bp2,Jmjd6,Slc16a1,Aida,Insl6,Max,Rpgrip1l,Cd200r4,Fscn1,Lipg,Nqo1,Pou3f1,Parp3,Lif,Raet1e,Arg2,Oas1a,Usp12,Tnfsf15,Psma6,Nr3c1,Bcl2l11,Odc1,Fpr2,Map2k1,Pdk3,Trim12c,Eif4g2,Rab19,Rap1gap2,Sphk1,Errfi1,Timp1,Jak2,Irf7,Tnfaip3,Hmgn3,Vasn,Ddx58,Plac8,Sp140,Ifi211,Rnf139,Itga9,P2ry14,Tnfrsf1b,Zc3hav1,Akt3,Tnc,Apobec3,Aebp2,Ppm1k,Pnpt1,Slfn1,Arrdc4,Slc30a1,Psmb9,Med21,Ccl2,Oas3,Batf,H2-Q6,D1Ertd622e,Psmb8,Sco1,Trafd1,Spen,Hspa2,Antxr1,Dgkh,Rhoq,Sipa1l1,Dnajb2,Igsf9,Gpr84,Mob3b,Ccng2,Gsr,Hcar2,Csf1,Nupr1,Ptpn2,Fzd5,Ptk2,Gda,Fosb,Rac3,Etv6,Kdm5b,Acvr1b,Dusp1,G3bp2,Saa3,Tnfrsf8,Cnn2,Lhx2,Tnfsf9,Casp2,Zbtb5,Bmp2,Tlr3,Slc30a4,Ifi205,Plat,H2-T10,Oas1g,Ppm1l,Ppp2r5a,Tnfrsf14,Keap1,Ttc39b,Rfx5,Gpr141,Polr2g,Trib3,Pim3,H2-Aa,Lztfl1,Sik3,Arhgap26,P2ry2,Mt2,Rnf19a,Tmem176a,Acvrl1,Rbbp8,Casp8,Nampt,Pikfyve,Phf6,Sdc4,Abcc1,Pla2g4a,Etv5,Ogfrl1,Brd2,Stxbp3,Ifi214,Carhsp1,Tra2a,Ednrb,Cd55,Ccdc88b,Agrn,Traf3ip2,Ifna4,Cyth3,Mtus1,Map4k4,Gng4,Dyrk2,Cdc42ep2,Icosl,Xcr1,Ass1,Nfkbie,Tapbpl,Ptprj,Nmi,Tdrd7,Uaca,Plpp1,Hmox1,Rnd3,Cd300lf,Tiparp,Rhoh,Atp2b4,Mov10,Ptger4,Mcoln2,Mmp13,Adora2a,Aim2,Ust,Adgrg6,S100a8,Tnfsf4,Nr4a1,Trim21,Radx,H2-Q7,Ctla2a,Nectin2,Enpp4,Hivep3,Itgb8,Nes,Cd80,Bcl2a1d,Cd38,Sat1,Cdyl,Fam129a,Isg20,Adgrl2,Rab32,Usp18,Slc39a4,Htr2b,Rims3,Il4ra,Tnip1,Ncoa7,Slc7a11,Kremen1,Chst11,Lyn,Sell,Clcf1,Fam20c,Klf3,Txnrd1,Hp,Pik3r6,Pde3b,Stat4,Sh3bp4,Ric1,Ccl4,Sod2,Ccl3,Oasl1,Bfar,Col4a2,Pml,Brwd3,Eya4,Igf1r,Psip1,Vrk2,Fgr,Map3k6,Phip,Cdkn2d,Ifnb1,Ccl5,Trim14,Serpinb9,Oas2,Pde4b,Junb,Malt1,Tlr1,Pdgfb,Dst,Ebi3,Mafg,Xaf1,Lpar1,Piezo1,Ikbke,Batf2,Gpr68,Sema3c,Smpdl3b,Stat3,Egr3,Ggct,Tfec,Kcnj2,4932438A13Rik,Sec24a,Crkl,Rin2,Hat1,Nlrc4,Spint2,Stat1,Bcor,Flrt3,Il12rb1,H2-Q4,Adar,Maff,Hk3,Swap70,Ranbp2,Vegfc,Iigp1,Znrf3,Glipr2,Cxcl1,Ccl7,Ell2,Ap3b1,Rhou,Card6,Pf4,Apaf1,Tlr9,Spic,Ezr,Scyl2,Glrx,Ddit4,Sdc2,Klf2,Pde1b,Birc2,Ntng2,Triobp,Ccrl2,Htr2a,Vps54,Myc,Ppp4r2,Olfr56,Clec2d,Ccl9,Il6,Sap30,Cflar,Vasp,Mamld1,Cd34,Grk3,N4bp1,Plk2,Prnp,Sema4a,Rel,Gem,Samhd1,Ctsc,Hk2,Itgav,Gja1,Relb,Psd4,Pcx,Tnfsf14,Slc7a2,Palld,Procr,Pdgfc,Dram1,Fubp1,Hmga2,Ppp2r3a,Dtx2,Ubash3b,Nlrc5,Gfpt1,Plaat3,Egr2,Magohb,Kitl,Pilra,Me1,H3f3b,Myd88,Met,Rtn2,Mafk,Kmt5a,Eno1,Vcam1,Dnajb4,Cxcl14,Rapgef5,Zhx2,Calcrl,Rgcc,Pmepa1,Egr1,Mmp25,Dusp4,Bcl6,Ppp1r15a,Rcan1,Mark2,Gadd45b,Cnot4,Spred3,Rnd1,Kdm6b,Cgas,Txn1,Il1rn,Nek6,Ifna5,Rilpl1,Mthfr,Traf2,Znfx1,Stk40,Lrp4,Tifa,Hlx,Serpinb6b,Rnf14,Nfkbil1,Tut7,Hivep2,Clec5a,Jarid2,Pvr,Il18rap,Rrs1,Ldlr,Smg7,Nfkbib,Tomm70a,Fgl2,Il18,Zc3h12a,Sele,Gfi1,Prokr1,Trip10,Serpinb9b,Usp42,Kif3c,Bst1,Cmklr1,Cenpe,Lnpk,Hspa1a,Rab11fip1,Tspo,Phlpp1,Fmnl2,Gk,Klhl25,H60b,Cx3cr1,Intu,Prkar2b,Dnaja1,Socs7,Stau1,Gng12,Resf1,Elmod2,Cish,Sema4c,Hmga1,Mtcp1,Nsd3,Gclm,Dtx3l,Sgk3,Phldb1,Mmp14,Ddx60,C1ra,Med13,Sav1,Klf6,Slpi,Ddx4,Nfil3,Hilpda,Casz1,Ksr1,Pde7b,Traf1,Syne2,Mmd,Spn,Pik3cd,Hsph1,Dusp5,Sde2,Plscr1,F10,Nfxl1,Adora2b,Ppp2r2a,Ppp1r12b,Sqstm1,Dbnl,Osm,Klf7,Pbx1,Plcl2,Mmp9,Lgals9,Il15ra,Cd274,Kctd12,Cited2,Tpx2,Bambi,Rsad2,Nsmaf,Fam162a,Jun,Daxx,Il1a,Prdx1,Kif9,Atf3,Caml,Psd,Pfkl,Dr1,Kat2b,Irs2,Uchl1,Icam1,Hk1,Arid5b,Tbc1d1,Abracl,Cd180,Il13ra1,Gclc,Vcan,Flt1,Kcna3,Asb13,Gpc1,Wdr43,Cox17,Treml4,Bcl2a1a,Phlda1,Peli1,Stat2,Dock10,Tcea1,Cdyl2,Zbp1,Lcp2,Tlr6,Rictor,Ptges,Pgk1,Inhba,Traf5,Dek,Tyk2,Clec4n,Rgs14,Nlrp3,Scimp,Eef1e1,Azi2,Ifna2,Arid4a,Socs3,Rnf34,Plekhn1,Rbpms,Stat5a,Map3k8,Gpr85,Eif2ak2,Plagl1,Pdpn,Socs1,Nfkbia,Dcp2,Adrb2,Gtpbp2,Evl,Slamf8,Ppp1r14b,Igsf8,Mllt6,Birc3,S1pr2,Ifrd1,Stx6,Zc3h7a,A530064D06Rik,Gsap,Col18a1,Il15,Ociad1,Gng11,Ccl8,Cebpd,Pdgfrb,Rab3ip,Nr1h3,Tle3,Prag1,Prkx,Nfkb2,Perm1,Il2rg,Phgdh,Lox,Ptgs2os2,Mid1,Nrp2,Cpeb4,Plek,Nmral1,Nfkbiz,Ifnar1,4930453N24Rik,Nfkb1,Cdk5r1,Prkce,Hsd17b12,Btg2,Mlkl,Acp5,Ifna1,Tet2,Pmaip1,Sla,Isg15,Il1b,Cacybp,Bcl2a1b,Dusp6,Inpp5b,P2ry12,Rffl,Ifna6,Nck1,Tnfsf10,Agtrap,Gpr35,Trim56,Spata13,Zfp513,Ifi207,Cdkn1a,Katna1,Daam1,Mosmo,Clic4,Tmem67,Tnip3,Sinhcaf,Srgn,Ifitm1,Bnip3,Cd14,Samsn1,P2ry13,Mefv,Il12b,Spred1,Slfn3,Cxcl9,Scn1b,Htra1,Irgm2,Sesn3,Parp9,Ifi208,Wdr59,Smc5,Gbp4,Tab2,Nos2,Gcnt2,Csf3,Asns,Tnfsf8,Aoah,Tlk2,Adgre4,Klf8,Themis2,B430306N03Rik,Tlr2,Clec4d,Pim1,Clec4e,Irak2,Itgal,Slamf7,Rgs1,Pid1,Notch1,Abcb1a,Ets2,Egln3,Ehd1,Shfl,Hdac1,Rgl1,Plau,Cdc42ep4,Adam19,Plaur,Hinfp,Acvr1,Sp110,D16Ertd472e,Tent2,Xrn1,Homer1,Tsku,Stap1,Nod2,Pla2g7,Flrt2,Nfkbid,Tmem176b,Tmsb10,Serpine1,Carmil1,Adap2,Tap2,Lrp8,Gadd45g,Irak3,Zfp36,Cop1,Morc3,Clic5,Tent4a,Atm,Acsl1,Higd1a,Olr1,Fos,Abr,Ahrr,Ankib1,Timeless,Fam72a,Tank,Hspa1b,Rab9,Whamm,H2-M2,Arhgef3,Stoml1,Dusp2,Rgs3,Helz2,Ptch1,Lmo4,C1rl,Ahr,Ifi209,Sdc1,Arf4,H2-T24,Ier3,Axl,Irf8,Acsl5,Gpsm2,Grina,Trim13,Tap1,Hhex,Dhx58,Syk,Fzd1,Trim36,Ifi204,Zswim4,Prdm1,Milr1,Pik3r5,Noct,Rab20,Ccr1,Ciapin1,Zyx,Pim2,Ago3,Ccnj,Larp1,Ankrd17,Wars,Nox1,Tshz1,Msr1,Fignl2,Jdp2,Nod1,Cxcl2,Rabgef1,Ift22,Rnf31,Sec24b,Fpr1,Treml2,Actb,Gsdmd,C3,Cd74,Fabp3,Klrk1,Ak4,Ero1l,Ptafr,Cxcl10,Lrch1,Fam111a,Serpina3f,Tnks1bp1,Hck,Src,H2-Ab1,Lst1,Lcn2,Tapbp,Hcls1,Prdx5,Cxcl3,Tarm1,Cycs,Ncoa5,Trib1,Ripk3,Cysltr2,Cd200,Mpp7,Pou2f2,Dnase1l3,Abcc4,Optn,Apba1,Gnb4,Mndal,Dcun1d3,Phactr4,Tulp3,Mecp2,Ppp2r1b,Cenpj,Hopx,Fcgr1,Slc9a1,Ppfia3,Parp14,Maml2,Dio2,Ifih1,Dusp16,Csf3r,Csrnp1,Spry2,Dock4,Dennd1b,Aff1,Phf11a,Pde5a,Myo10,Dcp1a,Plagl2,Fcgr4,Dync1i2,Rnf19b,Kmo,Oas1b,Zeb1,Kdm4a,Itga5,Hif1a,Ccnd2,Psme2,Ciita,Ppp6r1,Jag1,Dusp8,Prdm9,Cacnb3,Mt1,Thbs1,Fbxo4,Ddhd1,Ikbkg,Asap3,Rhof,Casp3,Zmynd15,Crlf3,Nr4a3,Psmd10,Ccnd1,Gpr132,Mdm2,Psme1,Mapkapk2,Pttg1,Tal2,Kdr,Cacna1d,Mdfic,Plekha2,Cx3cl1,Ift57,Dcbld2,Zfp281,Serp1,Irgm1,Siglece,Fcgr2b,Gch1,Arid5a,Fut8,Ube2e2,Notch2,Rab10,Tagap,Gdf15,Fabp7,Pdlim7,Cst7 |
| 6.892e-41 | -92.48 | regulation of signal transduction | biological process | GO:0009966 | 2769 | 369 | 20694 | 1406 |
Plek,Bmp2,Casp2,Acvr1b,Dusp1,Lox,Mid1,Ifna1,Mlkl,Sla,Il1b,Pmaip1,Trib3,Tlr3,Prkce,Cdk5r1,Nfkb1,Tnfsf10,Gpr35,Acvrl1,Ifna6,Nck1,Casp8,Spata13,Sik3,Bcl2a1b,Dusp6,Arhgap26,Rffl,P2ry12,Cd14,Bnip3,Il12b,Traf3ip2,Mosmo,Tnip3,Bcl2l11,Bcl2a1a,Peli1,Nr3c1,Treml4,Map2k1,Fpr2,Usp12,Flt1,Lif,Gpc1,Tnfsf15,Clec4n,Scimp,Nlrp3,Zc3hav1,Rgs14,Akt3,Errfi1,Timp1,Jak2,Tlr6,Rap1gap2,Sphk1,Zbp1,Traf5,Vasn,Rictor,Inhba,Tnfaip3,Irf7,Ccl2,Nfkbia,Adrb2,Birc3,Socs3,Ifna2,Rnf34,Rbpms,Eef1e1,Eif2ak2,Socs1,Map3k8,Pdgfrb,Ptpn2,Fzd5,Ccl8,Nr1h3,Tle3,Prag1,Ptk2,Sipa1l1,S1pr2,Il15,Nupr1,Csf1,Mob3b,Dusp5,Plscr1,Hsph1,Rapgef2,F10,Adora2b,Cyfip1,Ptgs2,Ksr1,Traf1,Mmp9,Sirt1,Plcl2,Ccl22,Kctd12,Lgals9,Itpr1,Acod1,Sqstm1,Trim30a,Myadm,Osm,Cav1,Angpt1,Prdx1,Asah2,Acpp,Rasgrp1,Ccl12,Atf3,Bambi,Cited2,Il1a,Daxx,Mapkbp1,Tnf,Rsad2,Fam162a,Jun,Tcf4,Aida,Rpgrip1l,Gclc,Cd180,Psd,Cd40,Mtdh,Nlgn2,Icam1,Uchl1,Nfkbil1,Casp4,Rrs1,Casp1,Hap1,Ifna5,Traf2,Wdfy1,Rhbdf2,Rnf14,Stk40,Lrp4,Tifa,Ripk2,Mul1,Il18,Zc3h12a,Gfi1,Marco,Gpr18,Irf1,Phlpp1,Map2k4,Intu,Il10,Cx3cr1,Bst1,Cmklr1,Plpp3,Irf4,Gclm,Ptgir,Sgk3,Mmp14,Ddx60,Cish,Sema4c,Edn1,Dnaja1,Socs7,Fas,Prnp,Grk3,Cacnb3,Thbs1,Samhd1,Ctsc,Hif1a,Il6,Jag1,Dusp8,Cflar,Pdgfc,Mdm2,Hmga2,Ppp2r3a,Ikbkg,Itgav,Psmd10,Tnfsf14,Psd4,Crlf3,Myd88,Met,Irgm1,Fcgr2b,Kdr,Ubash3b,Nlrc5,Mdfic,Cx3cl1,Kitl,Gdf15,Dusp4,Bcl6,Gadd45b,Spred3,Cgas,Il1rn,Rcan1,Kmt5a,Egr1,Pmepa1,Notch2,Stat3,Src,Smpdl3b,Hcls1,Pdgfb,Ikbke,Lpar1,Optn,Stat1,Crkl,Ripk3,Cysltr2,Adar,Ncoa5,Trib1,Apaf1,Tlr9,Pf4,Slc9a1,Scyl2,Glrx,Ddit4,Ezr,Parp14,Cenpj,Znrf3,Phactr4,Tulp3,Vegfc,Ppp2r1b,Ccl7,Card6,Glipr2,Plagl2,Htr2a,Pde5a,Myc,Ccl9,Zeb1,Dusp16,Birc2,Spry2,Tank,Fam72a,Dusp2,Rgs3,Arhgef3,Higd1a,Atm,Abr,Bcl2a1d,Ier3,Fam20c,Hhex,Dhx58,Pik3r6,Acsl5,Axl,Grina,Trim13,Ptch1,Htr2b,Clcf1,Tnip1,Kremen1,Chst11,Lyn,Prdm1,Pik3r5,Bfar,Pim2,Ago3,Eya4,Pml,Ccr1,Ccl4,Pde3b,Syk,Sh3bp4,Ccl3,Fzd1,Sod2,Malt1,Rnf31,Pde4b,Tlr1,C3,Cd74,Phip,Nox1,Igf1r,Fgr,Vrk2,Map3k6,Ankrd17,Ccl5,Rabgef1,Nod1,Ifnb1,Cdkn2d,Gcnt2,Csf3,Dyrk2,Map4k4,Ptprj,Htra1,Spred1,Wdr59,Tab2,Irgm2,Sesn3,Ifna4,Cyth3,Parp9,Itgal,Irak2,Cd300lf,Notch1,Rhoh,Rgs1,Pid1,Uaca,Tlr2,Hmox1,Plau,Hdac1,Tnfsf4,Plaur,Acvr1,S100a8,Atp2b4,Ptger4,Adora2a,Gadd45g,Irak3,Nectin2,Homer1,Tsku,Stap1,Nod2,Nfkbid,Serpine1 |
| 8.008e-41 | -92.33 | MARKEY_RB1_ACUTE_LOF_DN | MSigDB lists | MARKEY_RB1_ACUTE_LOF_DN | 225 | 90 | 15632 | 1249 |
Tor3a,Mndal,Psme2,Isg20,Ifi211,Ifit3b,Ifi204,Ldlr,Ccl4,Fam162a,Sod2,Bcl2a1b,Plac8,Tor1aip2,Fcgr2b,Ifi214,Sgcb,Ifi207,Ccl5,Ccr1,Irf7,Slfn4,Sap30,Hp,Tmem229b,Gcnt2,Cxcl1,Acp2,Ifit2,Ifi209,Sat1,Prdx5,Nupr1,Mcoln2,Ch25h,Psmb10,Ifih1,Gbp3,Usp18,Rnf34,Psmb8,Casp4,Gbp7,Ifit3,Procr,Ifi203,Pla2g7,Stat1,Socs3,Ifi35,Hcls1,Sh3bgrl2,Pfkl,Agrn,Ifit1bl1,Znfx1,Cxcl14,Il18bp,Adar,Pnpt1,Fcgr1,Tap1,Ifit1bl2,Nampt,Ifi208,Ube2l6,Uba7,Fndc3a,Serpinb9,Fpr1,Cxcl10,Clec4d,Tgfbi,Ak4,Grina,Slfn3,Bcl2a1a,Cmpk2,Glrx,Ifi213,Ifi205,Psmb9,Pnp2,Tapbp,Bcl2a1d,Sphk1,Isg15,Gbp2,Hck,Daxx |
| 9.497e-41 | -92.16 | regulation of innate immune response | biological process | GO:0045088 | 286 | 95 | 20694 | 1406 |
Rasgrp1,Ccr1,Irgm1,Myd88,Tnf,Ifi204,Rsad2,Rnf135,Nlrc5,Il12b,Cgas,Tlr1,Cd74,Treml2,Cd14,Ifi214,Serpinb9,Tnip3,Fgr,Ankrd17,Samhd1,Cd86,Plscr1,Pik3r6,Dhx58,Tap1,Lgals9,Mapkapk2,Trim30a,Ifi209,Prkce,Cav1,Lyn,Tnip1,Acod1,Ifi205,Tlr3,Trafd1,H60b,Parp14,Irf1,Slamf8,Tlr9,Nfkbia,Aim2,Socs1,Stat5a,Clec2d,Nectin2,Nr1h3,Ddx60,Irf4,Ptpn2,Irak3,Lrp8,Tap2,Nod2,A530064D06Rik,Ifih1,Nmi,Trim12c,Il18rap,Ifi203,Fpr2,Pvr,Peli1,Smpdl3b,Treml4,Nfkbil1,Ikbke,Wdfy1,Tifa,Ifi208,Ripk2,Parp9,Mul1,Irgm2,Raet1e,Klrk1,Mndal,Zc3hav1,Gfi1,Irak2,Cd300lf,Ifi211,Adar,Ddx58,Clec4e,B430306N03Rik,Tlr2,Tnfaip3,Irf7,Tlr6,Nlrc4,Zbp1 |
| 1.400e-40 | -91.77 | GSE45365_NK_CELL_VS_CD11B_DC_DN | MSigDB lists | GSE45365_NK_CELL_VS_CD11B_DC_DN | 193 | 83 | 15632 | 1249 |
Clec4d,Pim1,Dusp5,Kdm6b,Rnf19b,Ptges,Il1b,Igf2bp2,Clic4,Gcnt2,Il1rn,Cxcl1,Serpine1,Osm,Cd86,Gch1,Pde4b,Junb,Stx11,Maff,Vasp,AA467197,Csf3,Nfkbid,Phlda1,Slc7a5,Btg2,Rnd1,Icam1,Lif,Csrnp1,Ch25h,Marcksl1,Tnfaip3,Cd14,Csf3r,Timp1,Stat5a,Dusp1,Sele,Slc15a3,Ccdc86,Cish,Ier3,Mefv,Lyn,Rab20,Mmp9,Sema4c,Nfil3,Trem1,Ccl4,Tnip1,Cd300lf,Tnfaip2,Jdp2,Ppp1r15b,Birc3,S100a8,Etv6,Plscr1,Zfp36,Cyth3,Pgm1,Fpr2,Egr1,Pgs1,Nfkbiz,Olr1,Tle3,Clec4e,Pilra,Sdc4,Ptpn2,Tiparp,Ets2,Fos,Bcl2l11,Syk,Nfkbia,Cxcl14,Chst11,Il6 |
| 1.507e-40 | -91.69 | response to stimulus | biological process | GO:0050896 | 8373 | 808 | 20694 | 1406 |
Ikbkg,Rhof,Rtp4,Casp3,Nr4a3,Ccnd1,Gpr132,Mdm2,Mapkapk2,Pttg1,9930111J21Rik1,Kdm4a,Hif1a,Itga5,Ccnd2,Ciita,Jag1,Cacnb3,Thbs1,Mt1,Fbxo4,Trem1,Fut8,Ube2e2,Hmgcs1,Notch2,Rab10,Tagap,Fabp7,Gdf15,Gbp9,Kdr,Cacna1d,Mdfic,Cx3cl1,Dcbld2,Ift57,Serp1,Irgm1,Fcgr2b,Gch1,Arid5a,Prdx5,Tarm1,Cxcl3,Trib1,Cysltr2,Ripk3,Abcc4,Dnase1l3,Pou2f2,Optn,Gnb4,Mndal,Ak4,Klrk1,Ero1l,Ptafr,Cxcl10,Lrch1,Serpina3f,Tnks1bp1,Src,Hck,H2-Ab1,Lst1,Lcn2,Gbp3,Tapbp,Hcls1,Ifih1,Tgtp1,Csrnp1,Csf3r,Spry2,Dock4,Dennd1b,Pde5a,Tent5a,Dcp1a,Fcgr4,Rnf19b,Oas1b,Zeb1,Kmo,Phactr4,Tulp3,Dcun1d3,Mecp2,Cenpj,Trim12a,Slc9a1,Fcgr1,Parp14,Stip1,Dio2,Maml2,Ifit1bl2,Ptch1,Ahr,Sdc1,Ifi209,C1rl,H2-T24,Arf4,Ier3,Gpsm2,Irf8,Axl,Trim13,Hhex,Tap1,Dhx58,Tent4a,Atm,Ifit1,Acsl1,Higd1a,Olr1,Abr,Fos,Il18bp,Ahrr,Timeless,Hspa1b,Rab9,Tank,H2-M2,Arhgef3,Stoml1,Rgs3,Larp1,Ankrd17,F830016B08Rik,Nox1,Srm,Nod1,Cxcl2,Ift22,Rnf31,Fpr1,Actb,Gsdmd,Cd74,C3,Syk,Fzd1,Ifi204,Prdm1,Pik3r5,Milr1,Noct,Rab20,Ccr1,Zyx,Ago3,Flnb,Adgre4,Mx2,Themis2,Tlr2,Clec4d,Clec4e,Pim1,Irak2,Slamf7,Itgal,Rgs1,Pid1,Notch1,Gm4841,Ifi44,Cxcl9,Scn1b,Sesn3,Irgm2,Ifi208,Parp9,Tab2,Nos2,Gbp4,Smc5,Wdr59,Gcnt2,Csf3,Asns,Tnfsf8,Tlk2,Sp110,Homer1,Stap1,Nfkbid,Flrt2,Pla2g7,Nod2,Adap2,Serpine1,Tap2,Igtp,Lrp8,Gadd45g,Irak3,Zfp36,Cop1,Clic5,Abcb1a,Egln3,Ehd1,Shfl,Clcn7,Hdac1,Rgl1,Cdc42ep4,Plau,Acvr1,Plaur,Hinfp,Nfkbiz,Ifnar1,Nfkb1,Prkce,Cdk5r1,Mlkl,Btg2,Trim34a,Acp5,Ifna1,Pmaip1,Isg15,Acp2,Il1b,Nfkb2,Perm1,Il2rg,Lox,Phgdh,Cpeb4,Nrp2,Plek,Nmral1,Daam1,Clic4,Tmem67,Tnip3,Bnip3,Ifitm1,Cd14,P2ry13,Mefv,Il12b,Cacybp,Srxn1,Bcl2a1b,Gm5431,P2ry12,Inpp5b,Nck1,Ifna6,Tnfsf10,Agtrap,Gpr35,Spata13,Trim56,Cdkn1a,Ifi207,AA467197,Susd6,Zbp1,Lcp2,Tlr6,Rictor,Pgk1,Inhba,Traf5,Tyk2,Clec4n,Rgs14,Gramd1a,Nlrp3,Slc25a25,Flt1,Tmem229b,Asb13,Treml4,Bcl2a1a,Peli1,Snx10,Stat2,Dock10,Ifrd1,S1pr2,Il15,Gng11,Ccl8,Pdgfrb,Slc25a22,Tle3,Nr1h3,Prkx,Ch25h,Eef1e1,Azi2,Gm4951,Socs3,Ifna2,Slfn9,Rbpms,Plekhn1,Kif5c,Rnf34,Stat5a,Ascc3,Map3k8,Eif2ak2,Gpr85,Socs1,Pdpn,Evl,Nfkbia,Adrb2,Slamf8,Ppp1r14b,Birc3,Dbnl,Sqstm1,Osm,Klf7,Plcl2,Mmp9,Il15ra,Lgals9,Cd274,Slpi,Klf6,Nfil3,Traf1,Ksr1,Pde7b,Spn,Hsph1,Pik3cd,Ldha,Plscr1,Sde2,Adora2b,F10,Ppp2r2a,Ppp1r12b,Pfkl,Kat2b,Irs2,Uchl1,Hk1,Icam1,Slc25a12,Arid5b,Cd180,Il13ra1,Gclc,Nt5c3,Cited2,Bambi,Rsad2,Rcsd1,Jun,Fam162a,Il1a,Daxx,Prdx1,Atf3,Caml,Nfkbib,Sbds,Fgl2,Il18,Zc3h12a,Sele,Gfi1,Prokr1,Trip10,Serpinb9b,Nek6,Ifna5,Traf2,Tifa,Lrp4,Nfkbil1,Hivep2,Clec5a,Jarid2,Idi1,Il18rap,Ldlr,Dnaja1,Prkar2b,Gng12,Socs7,Sema4c,Cish,Resf1,Hmga1,Gclm,Dtx3l,Mmp14,Ddx60,Sgk3,C1ra,Sav1,Tgtp2,Lnpk,Cmklr1,Hspa1a,Tspo,Phlpp1,Gk,H60b,Asf1a,Cx3cr1,Hk2,Gja1,Itgav,Relb,Tnfsf14,Slc7a2,Palld,Procr,Pdgfc,Hmga2,Dtx2,Il6,Cflar,Vasp,N4bp1,Slfn8,Grk3,Plk2,Prnp,Sema4a,Rel,Gem,Ctsc,Samhd1,Vcam1,Eno1,Cxcl14,Rapgef5,Ext1,Calcrl,Rgcc,Egr1,Mmp25,Bcl6,Ppp1r15a,Rcan1,Mark2,Kdm6b,Cgas,Il1rn,Txn1,Rnd1,Ubash3b,Nlrc5,Egr2,Plaat3,Pilra,Kitl,Me1,Met,Myd88,Crkl,Rin2,Nlrc4,Flrt3,Stat1,Il12rb1,H2-Q4,Mcm10,Adar,Swap70,Mcm6,Pdgfb,Ebi3,Dst,Xaf1,Lpar1,Piezo1,Batf2,Ikbke,Smpdl3b,Sema3c,Gpr68,Stat3,Ggct,Egr3,Tfec,Klf2,Pde1b,Birc2,Ccrl2,Ntng2,Htr2a,Myc,Olfr56,Ccl9,Clec2d,Vegfc,Iigp1,Znrf3,Cxcl1,Ccl7,Rhou,Ap3b1,Tlr9,Apaf1,Pf4,Gbp2,Ezr,Glrx,Scyl2,Ddit4,Rab32,Usp18,Slc39a4,Htr2b,Kremen1,Tnip1,Slc7a11,Il4ra,Lyn,Sell,Clcf1,Hp,Txnrd1,Pik3r6,Cd80,Ifit1bl1,Gbp2b,Bcl2a1d,Cd38,Fam129a,Isg20,Adgrl2,Psip1,Igf1r,Map3k6,Vrk2,Fgr,Phip,Ifnb1,Cdkn2d,Serpinb9,Trim14,Ccl5,Oas2,Pde4b,Junb,Malt1,Tlr1,Pde3b,Sh3bp4,Stat4,Ccl4,Sod2,Ccl3,Oasl1,Col4a2,Pml,Eya4,Uaca,Gsta3,Plpp1,Hmox1,Rnd3,Cd300lf,Tiparp,Rhoh,1600014C10Rik,Ifna4,Map4k4,Cdc42ep2,Icosl,Dyrk2,Gng4,Cd69,Xcr1,Cmpk2,Ass1,Nfkbie,Stx11,Nmi,Ptprj,Trim21,H2-Q7,Enpp4,Itgb8,Ptger4,Atp2b4,Mcoln2,Mmp13,Adora2a,Aim2,Adgrg6,S100a8,Tnfsf4,Nr4a1,Tlr3,Plat,Slc30a4,Ifi205,H2-T10,Oas1g,Tnfrsf14,Ppp2r5a,Ppm1l,Keap1,Lrrc8c,Gpr141,Trib3,Dusp1,Acvr1b,G3bp2,Mcm9,Tnfrsf8,Cnn2,Saa3,Lhx2,Tnfsf9,Zbtb5,Casp2,Bmp2,Ogfrl1,Stxbp3,Ifi214,Ednrb,Cd55,Ccdc88b,Traf3ip2,Agrn,H2-Aa,Sik3,Arhgap26,P2ry2,Mt2,Acvrl1,Stra6l,Pikfyve,Nampt,Casp8,Rbbp8,Abtb2,Sdc4,Uba7,Abcc1,Cp,Etv5,Pla2g4a,Rab19,Sphk1,Errfi1,Jak2,Lrp11,Timp1,Tnfaip3,Irf7,Vasn,Ddx58,Ifi47,Ifi211,Plac8,Itga9,Rnf139,Tnfrsf1b,P2ry14,Akt3,Zc3hav1,Lif,Raet1e,Arg2,Oas1a,Tnfsf15,Dnaja2,Nr3c1,Bcl2l11,Fpr2,Ifit3b,Map2k1,Pdk3,Trim12c,Dgkh,Hspa2,Spen,Rhoq,Sipa1l1,Dnajb2,Gpr84,Hcar2,Gsr,Csf1,Nupr1,Gm12185,Fzd5,Ptpn2,Ptk2,Rac3,Kdm5b,Fosb,Herc6,Tnc,Apobec3,Pnpt1,Psmb9,Slc30a1,Oas3,Batf,Ccl2,H2-Q6,Ifit3,Acod1,Itpr1,Cav1,Spire1,Trim30a,Cxcl11,Ccl22,Sirt1,Slc2a1,Etv3,Cd83,Cyfip1,H2-Eb1,Ralgds,Ier2,Ifit2,Oasl2,Bcl9,Gna15,Ifi213,Ptgs2,Rapgef2,Marf1,Cd86,Rap2c,Cd40,Nlgn2,Gbp8,Mtdh,Jmjd6,Slc16a1,Nqo1,Parp3,Selenow,Rnf135,Stxbp1,Mapkbp1,Tnf,Plk3,Slc13a3,Ly6a,Il27,Angpt1,Parp10,Asah2,Ccl12,Rras2,Rasgrp1,Slc31a1,Marco,Mx1,H2-T22,Gpr18,Usp53,Slfn2,Mul1,Ripk2,Slfn4,Mvp,Trim26,Casp4,Casp1,Hap1,Ifi203,Ccne1,Dgka,Trip13,Edn1,Serpinb2,Papss2,Hvcn1,Fas,Esd,Itga4,Lnpep,Irf4,Ccr3,Casp7,Ptgir,Ogfr,Rhoc,Plpp3,Gbp7,Serpina3g,Irf1,Cnp,Rab21,Il10,Map2k4,Irf2,Ppp1r15b |
| 2.189e-40 | -91.32 | REACTOME_IMMUNE_SYSTEM | MSigDB lists | REACTOME_IMMUNE_SYSTEM | 811 | 183 | 15632 | 1249 |
Lyn,Cdkn1a,Jak2,Casp8,Ikbkg,Trim21,Psme2,Nfkbib,Irs2,Nck1,Eif2ak2,Trim36,Nr4a1,Sqstm1,Syk,Phlpp1,Ifnb1,Dusp4,Fcgr2b,Trib3,Il2rg,Crkl,Tlr3,Vcam1,Irak2,Nfkb2,Lcp2,Dusp6,Vasp,Cd74,Usp18,Gbp3,Tnfaip3,Cd14,Traf2,H2-Q6,Nfkbie,Dhx58,Gbp9,Irf1,Tlr2,Socs3,Gbp7,Ube2e2,Flnb,Mapkapk2,Tlr6,Ifna1,Fbxo4,Jun,H2-Q4,Nfkbia,Il6,Peli1,Ppp2r5a,Kif3c,Cd55,Il1rn,Cd86,Ifit1bl2,Txn1,Uba7,Tyk2,Tlr1,Icam1,Dtx3l,Sell,Ube2e1,Psme1,H2-Q7,Pml,Ripk3,Nod1,Psmb9,Dync1h1,Ifnar1,Casp1,Map2k4,Asb13,Ifit3b,Tlr9,Oasl1,C3,Tax1bp1,Ppp2r1b,Rel,Rictor,Xaf1,Rap1gap2,Isg20,Evl,Cd34,Cd80,Nlrc4,Ptpn2,Spsb1,Itgav,Ifna5,Ctsc,Il18,Map3k8,Psmb6,Ripk2,Il1b,Keap1,Ikbke,Tap2,Cd274,Irf7,Map2k1,H2-Eb1,Icosl,H2-Aa,Tab2,Psmb10,Rnf135,Ifih1,Aim2,Irak3,Ifna2,Myd88,Rnf34,Ube2f,Oas3,Stat5a,Ifit2,Stat3,Mefv,Pik3cd,Ifi35,Kpna3,Stat1,Ubr4,Itgal,Ifit3,Irf8,Casp4,Birc3,Psmb8,Eif4g2,Lnpep,Oas1a,Rasgrp1,Casp2,Akt3,Nlrp3,Egr1,Tnfrsf14,Tap1,Ciita,Adar,Fcgr1,Zbp1,Fos,Psmd10,Nlrc5,Ifit1bl1,Nod2,Irf4,Ptafr,Oas1g,Sec24b,Oas2,Ube2l6,Ifna6,Stat2,Ddx58,Cd180,Il1a,Isg15,Socs1,Irf2,Malt1,Hck,Gbp2,Cd40,Birc2,Tank,Src,Mdm2,Psma6,Gbp4,Cish |
| 4.050e-40 | -90.70 | GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | MSigDB lists | GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | 186 | 81 | 15632 | 1249 |
Cxcl10,Ripk2,Oas1g,Rnf19b,Atp10a,Herc6,Tlr3,Sp110,Trafd1,Il15ra,Gtpbp2,Irf7,Tap2,Gch1,Ifit1bl2,Oas2,Parp12,Hk2,Stoml1,Wars,Nmi,Ddit4,Ube2l6,Trim26,Socs1,Trim12c,Isg15,Psmb10,Ddx58,Kdm4a,Usp18,Stat2,Pml,Myd88,Oas3,Psmb9,Casp1,Parp8,Ifit2,Rsad2,Carhsp1,Slc15a3,Ifi44,Ifit3b,Rab20,Irf1,Kif5c,Stat1,Oasl1,Ifi35,H3f3b,Cflar,Ogfr,Ifit3,Psmb8,Tdrd7,Dcp1a,Xaf1,Oas1a,Rnf19a,Plscr1,Psme2,Isg20,Trim14,Trim21,Rtp4,Atf3,Tap1,Ccl12,Rnf114,Eif2ak2,Spsb1,Gadd45b,Gsdmd,Ifit1bl1,Ezr,Phactr4,Cox17,Optn,Stard5,Il6 |
| 4.656e-40 | -90.57 | cellular response to organic substance | biological process | GO:0071310 | 2116 | 306 | 20694 | 1406 |
Ifna1,Pdgfc,Mdm2,Il1b,Trib3,Mapkapk2,Casp3,Ifnar1,Ifi205,Hk2,Tlr3,Ccnd1,Cdk5r1,Prkce,Keap1,Nr4a3,Nfkb1,Prnp,Nmral1,Cpeb4,Nrp2,Bmp2,Dusp1,Acvr1b,Il6,9930111J21Rik1,Saa3,Lox,Il2rg,Ppp1r15a,Cd14,Ifitm1,Ifi214,Gdf15,Cgas,Il1rn,Il12b,P2ry13,Stxbp3,Vcam1,Eno1,Fut8,Egr1,Rab10,Tnip3,Calcrl,Irgm1,Agtrap,Gpr35,Acvrl1,Myd88,Serp1,Ifna6,Arid5a,Gch1,Fcgr2b,Ifi207,Egr2,Kdr,Gm5431,Gbp9,Cacybp,Cx3cl1,P2ry12,Tnfrsf1b,Ifi211,Optn,Ifi47,Mndal,Nlrp3,Akt3,Gramd1a,Zc3hav1,Flrt3,Jak2,Tlr6,Stat1,Sphk1,Crkl,Ddx58,Tnfaip3,Irf7,Inhba,Cxcl3,Il12rb1,H2-Ab1,Egr3,Src,Stat3,Nr3c1,Gbp3,Hcls1,Pdk3,Fpr2,Snx10,Stat2,Flt1,Cxcl10,Ptafr,Ero1l,Ebi3,Klrk1,Pdgfb,Lpar1,Lrch1,Ptpn2,Pdgfrb,Dcp1a,Fcgr4,Myc,Ccl8,Gm12185,Zeb1,Ccl9,Kdm5b,Nr1h3,Ptk2,Ccrl2,Csf3r,Birc2,Rhoq,Pde1b,Hspa2,Ifih1,Tgtp1,Csf1,Il15,Spry2,Ccl2,Gbp2,Slc9a1,Evl,Adrb2,Nfkbia,Apaf1,Pf4,Tlr9,Ifit3,Ddit4,Glrx,Stip1,Birc3,Ezr,Iigp1,Socs3,Ifna2,Mecp2,Gm4951,Eef1e1,Vegfc,Socs1,Ccl7,Eif2ak2,Pnpt1,Stat5a,Cxcl1,Etv3,Sirt1,Ccl22,Cd274,Il15ra,Axl,Irf8,Itpr1,Ptch1,Htr2b,Acod1,Ahr,Ifi209,Cxcl11,Lyn,Cav1,Osm,Il4ra,Plscr1,Hspa1b,Tank,Rapgef2,Timeless,Cd86,Stoml1,Ifit1,Gbp2b,Acsl1,Nfil3,Cyfip1,Atm,Cd80,Klf6,Ifi213,Fos,Ifit2,Malt1,Actb,Junb,Pde4b,Oas2,Arid5b,Il13ra1,Cd180,Cd74,F830016B08Rik,Phip,Gbp8,Mtdh,Igf1r,Larp1,Cxcl2,Ccl5,Icam1,Slc16a1,Ifnb1,Srm,Nod1,Kat2b,Irs2,Rab20,Col4a2,Ccl12,Asah2,Atf3,Zyx,Ccr1,Pml,Bambi,Ccl4,Stxbp1,Sh3bp4,Stat4,Pde3b,Cited2,Syk,Tnf,Il1a,Ccl3,Daxx,Ifi204,Jun,Zc3h12a,Il18,Cd300lf,Irak2,Tiparp,Gm4841,Notch1,Pid1,Gfi1,Nfkbib,Flnb,Pim1,Tlr2,Cdc42ep2,Gcnt2,Csf3,Casp4,Nfkbil1,Ldlr,Nmi,Il18rap,Stx11,Hap1,Cmpk2,Ifi203,Jarid2,Casp1,Traf2,Ifna5,Cxcl9,Nos2,Gbp4,Ripk2,Ifi208,Mul1,Sesn3,Ifna4,Irgm2,Zfp36,Irak3,Itga4,Gclm,Tgtp2,Ccr3,Casp7,Stap1,Socs7,Dnaja1,Igtp,H2-Q7,Fas,Serpine1,Flrt2,Nod2,Cdc42ep4,Irf1,Acvr1,Nr4a1,Tnfsf4,Cx3cr1,Il10,Hspa1a,Gbp7,Ptger4,Atp2b4,Aim2,Ehd1,Egln3 |
| 5.919e-40 | -90.33 | biological regulation | biological process | GO:0065007 | 12113 | 1052 | 20694 | 1406 |
4930453N24Rik,Nfkb1,Prkce,Cdk5r1,Nfkbiz,Ifnar1,Tet2,Pmaip1,Il1b,Sla,Isg15,Slc39a14,Btg2,Hsd17b12,Mlkl,Ifna1,Acp5,Il2rg,Ptgs2os2,Mid1,Phgdh,Lox,Nfkb2,Perm1,Nrp2,Cpeb4,Nmral1,Plek,Srgn,Sinhcaf,Tnip3,Mosmo,Clic4,Daam1,Tmem67,P2ry13,Il12b,Mefv,Ifitm1,Bnip3,Samsn1,Tha1,Cd14,Inpp5b,Rffl,P2ry12,Cacybp,Dusp6,Bcl2a1b,Ifi207,Cdkn1a,Trim56,Zfp513,Spata13,Katna1,Ifna6,Nck1,Gpr35,Agtrap,Tnfsf10,Pgk1,Inhba,Ptges,Rictor,Tyk2,Traf5,Dek,Cdyl2,Zbp1,Tcea1,Tlr6,Lcp2,Rgs14,Nlrp3,Scimp,Clec4n,Asb13,Kcna3,Gpc1,Wdr43,Flt1,Vcan,Snx10,Stat2,Dock10,Cox17,Treml4,Peli1,Bcl2a1a,Phlda1,Gsap,Col18a1,Zc3h7a,A530064D06Rik,Ociad1,Gng11,Il15,S1pr2,Ifrd1,Stx6,Rab3ip,Prag1,Prkx,Nr1h3,Tle3,Ccl8,Pdgfrb,Cebpd,Map3k8,Stat5a,Pdpn,Socs1,Eif2ak2,Gpr85,Plagl1,Azi2,Eef1e1,Rnf34,Rbpms,Plekhn1,Socs3,Ifna2,Arid4a,Birc3,Mllt6,Slamf8,Gtpbp2,Dcp2,Nfkbia,Adrb2,Evl,Ppp1r14b,Igsf8,Klf7,Osm,Pbx1,Dbnl,Sqstm1,Lgals9,Il15ra,Kctd12,Cd274,Plcl2,Mmp9,Syne2,Mmd,Pde7b,Ksr1,Traf1,Ddx4,Nfil3,Slpi,Klf6,Hilpda,Casz1,F10,Adora2b,Nfxl1,Ppp1r12b,Ppp2r2a,Pik3cd,Hsph1,Spn,Sde2,Dusp5,Plscr1,Uchl1,Irs2,Kat2b,Icam1,Hk1,Atp13a1,Pfkl,Psd,Dr1,Cd180,Gclc,Il13ra1,Abracl,Tbc1d1,Arid5b,Fam162a,Jun,Rsad2,Nsmaf,Daxx,Il1a,Tpx2,Cited2,Bambi,Atf3,Caml,Prdx1,Kif9,Nfkbib,Prokr1,Trip10,Sele,Gfi1,Serpinb9b,Tomm70a,Zc3h12a,Fgl2,Il18,Tifa,Lrp4,Hlx,Stk40,Znfx1,Rnf14,Serpinb6b,Nek6,Mthfr,Traf2,Rilpl1,Ifna5,Pvr,Jarid2,Smg7,Ldlr,Il18rap,Rrs1,Nfkbil1,Tut7,Clec5a,Hivep2,Hmga1,Mtcp1,Nsd3,Socs7,Stau1,Gng12,Prkar2b,Dnaja1,Elmod2,Resf1,Sema4c,Cish,C1ra,Sgk3,Mmp14,Phldb1,Ddx60,Sav1,Med13,Dtx3l,Gclm,Tspo,Rab11fip1,Lnpk,Hspa1a,Cmklr1,Cenpe,Bst1,Usp42,Kif3c,Cx3cr1,H60b,Intu,Phlpp1,Fmnl2,Klhl25,Gk,Zmynd15,Crlf3,Ccnd1,Nr4a3,Psmd10,Casp3,Ikbkg,Rhof,Asap3,Pttg1,Mapkapk2,Tmtc2,Tal2,Mdm2,Gpr132,Psme1,Ciita,Ppp6r1,Atp11b,Dusp8,Jag1,Kdm4a,Ccnd2,Psme2,Hif1a,Itga5,Ddhd1,Thbs1,Mt1,Cacnb3,Prdm9,Fbxo4,Notch2,Rab10,Tagap,Ube2e2,Fut8,Cst7,Plod3,Gdf15,Fabp7,Slc4a7,Pdlim7,Cacna1d,Cx3cl1,Mdfic,Plekha2,Col11a2,Kdr,Siglece,Gch1,Arid5a,Fcgr2b,Zfp281,Ift57,Dcbld2,Irgm1,Serp1,Ncoa5,Cycs,Trib1,Tarm1,Cxcl3,Mpp7,Cd200,Ripk3,Cysltr2,Prdx5,Gnb4,Mndal,Optn,Dnase1l3,Pou2f2,Abcc4,Apba1,Lrch1,Fam111a,Serpina3f,Ero1l,Ak4,Klrk1,Cxcl10,Ptafr,Lcn2,Lst1,Tapbp,Hcls1,Tnks1bp1,H2-Ab1,Hck,Src,Spry2,Dennd1b,Aff1,Dock4,Ifih1,Csf3r,Csrnp1,Dusp16,Rnf19b,Dync1i2,Kmo,Oas1b,Zeb1,Phf11a,Myo10,Pde5a,Plagl2,Dcp1a,Fcgr4,Hopx,Mecp2,Ppp2r1b,Dcun1d3,Phactr4,Tulp3,Cenpj,Maml2,Dio2,Parp14,Fcgr1,Slc9a1,Ppfia3,Atp11a,C1rl,Ahr,Sdc1,Ifi209,Helz2,Ptch1,Lmo4,Grina,Trim13,Acsl5,Irf8,Axl,Gpsm2,Dhx58,Tap1,Hhex,Arf4,H2-T24,Ier3,Abr,Olr1,Fos,Ahrr,Ankib1,Tent4a,Atm,Higd1a,Acsl1,Stoml1,Arhgef3,Dusp2,Rgs3,Timeless,Fam72a,H2-M2,Whamm,Tank,Rab9,Hspa1b,Crim1,Jdp2,Nod1,Rabgef1,Cxcl2,Ankrd17,Larp1,Wars,Nox1,Tshz1,Msr1,Fignl2,Fabp3,C3,Cd74,Rnf31,Sec24b,Ift22,Treml2,Actb,Gsdmd,Fpr1,Trim36,Fzd1,Zswim4,Ifi204,Syk,Zyx,Ccr1,Ciapin1,Ago3,Ccnj,Pim2,Milr1,Pik3r5,Prdm1,Rab20,Noct,Themis2,Pim1,Clec4e,B430306N03Rik,Tlr2,Clec4d,Adgre4,Klf8,Pid1,Rgs1,Notch1,Irak2,Itgal,Slamf7,Ifi208,Parp9,Irgm2,Sesn3,Gbp4,Smc5,Wdr59,Tab2,Nos2,Scn1b,Cxcl9,Slfn3,Spred1,Htra1,Tlk2,Tnfsf8,Aoah,Asns,Csf3,Gcnt2,Tmsb10,Tmem176b,Serpine1,Carmil1,Adap2,Nod2,Pla2g7,Flrt2,Nfkbid,Lrp8,Tap2,Tent2,D16Ertd472e,Sp110,Tsku,Stap1,Xrn1,Homer1,Morc3,Cop1,Clic5,Irak3,Gadd45g,Zfp36,Shfl,Ehd1,Egln3,Abcb1a,Hdc,Ets2,Hinfp,Plaur,Acvr1,Rgl1,Hdac1,Adam19,Plau,Cdc42ep4,Ppp2r5a,Ppm1l,Tnfrsf14,Oas1g,Keap1,Ifi205,Slc30a4,Plat,Tlr3,H2-T10,Trib3,Polr2g,Pim3,Ttc39b,Rfx5,Gpr141,Saa3,Cnn2,Tnfrsf8,G3bp2,Acvr1b,Dusp1,Casp2,Zbtb5,Bmp2,Lhx2,Tnfsf9,Ogfrl1,Stxbp3,Brd2,Ccdc88b,Cd55,Agrn,Traf3ip2,Slc28a2,Carhsp1,Ifi214,Ednrb,Tra2a,Arhgap26,Mt2,P2ry2,Lztfl1,H2-Aa,Sik3,Phf6,Rbbp8,Pikfyve,Nampt,Casp8,Pla2g4a,Etv5,Cp,Sdc4,Abcc1,Rnf19a,Tmem176a,Acvrl1,Tnfaip3,Irf7,Ddx58,Hmgn3,Vasn,Rap1gap2,Sphk1,Rab19,Timp1,Jak2,Errfi1,Zc3hav1,Akt3,Sp140,Plac8,Ifi211,P2ry14,Tnfrsf1b,Rnf139,Itga9,Tnfsf15,Psma6,Dnaja2,Raet1e,Lif,Oas1a,Usp12,Arg2,Odc1,Fpr2,Pdk3,Trim12c,Eif4g2,Map2k1,Nr3c1,Bcl2l11,Igsf9,Gpr84,Ccng2,Mob3b,Dnajb2,Csf1,Nupr1,Gsr,Hcar2,Spen,Tor1aip1,Antxr1,Hspa2,Dgkh,Sipa1l1,Rhoq,Gda,Ptk2,Kdm5b,Rac3,Fosb,Etv6,Ptpn2,Fzd5,Aebp2,Ppm1k,Pnpt1,Slfn1,Apobec3,Tnc,Psmb8,H2-Q6,D1Ertd622e,Trafd1,Sco1,Med21,Slc30a1,Arrdc4,Psmb9,Batf,Oas3,Ccl2,Cav1,Trim30a,Cxcl11,Myadm,Spire1,Slc31a2,Tbc1d13,Acod1,Samd9l,Itpr1,F11r,Riox2,Cd83,Arel1,Ccl22,Etv3,Sirt1,Bcl9,Oasl2,Ifit2,Ier2,Ptgs2,Ifi213,Gna15,Cyfip1,Ralgds,Rap2c,Cd86,Marf1,Tax1bp1,Rapgef2,Mier3,Dmxl2,Slc16a1,Jmjd6,Mtdh,Nlgn2,Mycl,Cd40,Rbl1,Igf2bp2,Dync1h1,Parp3,Pou3f1,Max,Rpgrip1l,Fscn1,Lipg,Cd200r4,Aida,Insl6,Nqo1,Pcgf5,Tcf4,Mapkbp1,Plk3,Tnf,Rnf135,Stxbp1,Rasgrp1,Ccl12,Rras2,Tmem123,Asah2,Acpp,Taf4b,Sertad3,Parp10,Mxd1,Il27,Pilrb1,Angpt1,Ikzf1,Osgin2,H2-T22,Usp53,Gpr18,Frmd4a,Marcksl1,Slc31a1,Crbn,Foxp4,Marco,Scarf1,Chmp4b,Slfn2,Ythdf1,Mul1,Ripk2,Rhbdf2,Wdfy1,Mvp,Tmod3,Usp25,Tmem178,Ccne1,Hap1,Ifi203,Casp1,Dgka,Casp4,Trim26,Frmd6,Hvcn1,Papss2,Pkp4,Fas,Rubcnl,Trip13,Edn1,Serpinb2,Rhoc,Ogfr,Ptgir,Ccr3,Svbp,Itga4,Lnpep,Irf4,Fchsd2,Serpina3g,Plpp3,Dach1,Rab21,Il10,Cnp,Ppp1r15b,Irf2,Map2k4,Irf1,Psd4,Pcx,Relb,Tnfsf14,Hk2,Gja1,Itgav,Dram1,Fubp1,Dtx2,Hmga2,Ppp2r3a,Slc7a2,Pdgfc,Procr,Palld,Vasp,Sap30,Cflar,Mamld1,Il6,Rel,Sema4a,Samhd1,Ctsc,Gem,Plk2,Grk3,Cd34,N4bp1,Prnp,Calcrl,Zhx2,Pmepa1,Egr1,Rgcc,Kmt5a,Dnajb4,Cxcl14,Rapgef5,Eno1,Vcam1,Rcan1,Mark2,Rnd1,Il1rn,Txn1,Kdm6b,Cgas,Spred3,Gadd45b,Cnot4,Bcl6,Dusp4,Mmp25,Ppp1r15a,Tor1aip2,Kitl,Pilra,Magohb,Nlrc5,Ubash3b,Plaat3,Egr2,Gfpt1,H3f3b,Me1,Rtn2,Mafk,Myd88,Met,Il12rb1,Adar,Maff,H2-Q4,Rin2,Hat1,Crkl,Stat1,Bcor,Flrt3,Nlrc4,Spint2,Ranbp2,Ahsa1,Swap70,Hk3,Lpar1,Ikbke,Batf2,Piezo1,Dst,Ebi3,Pdgfb,Mafg,Xaf1,Kcnj2,Tfec,Sec24a,Ampd3,4932438A13Rik,Gpr68,Sema3c,Smpdl3b,Egr3,Ggct,Stat3,Pde1b,Klf2,Ntng2,Triobp,Ccrl2,Birc2,Ppp4r2,Clec2d,Ccl9,Olfr56,Vps54,Myc,Htr2a,Glipr2,Cxcl1,Ell2,Card6,Rhou,Ap3b1,Ccl7,Vegfc,Znrf3,Iigp1,Ezr,Ddit4,Sdc2,Scyl2,Glrx,Tlr9,Pf4,Apaf1,Spic,Chst11,Lyn,Sell,Ncoa7,Tnip1,Slc7a11,Il4ra,Kremen1,Clcf1,Usp18,Rab32,Slc39a4,Htr2b,Pdzd11,Rims3,Txnrd1,Cnn3,Hp,Pik3r6,Fam20c,Klf3,Rmdn3,Bcl2a1d,Nes,Cd80,Adgrl2,Isg20,Cd38,Slc39a13,Sat1,Cdyl,Fam129a,Ifnb1,Cdkn2d,Trim14,Ccl5,Serpinb9,Fgr,Vrk2,Map3k6,Igf1r,Psip1,Cutc,Phip,Tlr1,Pde4b,Oas2,Malt1,Junb,Sod2,Oasl1,Ccl3,Sh3bp4,Stat4,Ric1,Pde3b,Ccl4,Pml,Brwd3,Eya4,Bfar,Col4a2,Plpp1,Rnd3,Hmox1,Uaca,Tdrd7,Rhoh,Cd300lf,Tiparp,Cyth3,Ifna4,1600014C10Rik,Atp10a,Xcr1,Ptprj,Tapbpl,Nmi,Stx11,Nfkbie,Ass1,Map4k4,Mtus1,Gng4,Cdc42ep2,Dyrk2,Mitd1,Icosl,Radx,H2-Q7,Trim21,Itgb8,Dhrs9,Nectin2,Hivep3,Enpp4,Slc12a9,Ctla2a,Aim2,Adora2a,Mcoln2,Atp2b4,Ptger4,Mov10,Mmp13,S100a8,Nr4a1,Tnfsf4,Xkr8,Ust,Adgrg6 |
| 6.569e-40 | -90.22 | positive regulation of cellular metabolic process | biological process | GO:0031325 | 3269 | 411 | 20694 | 1406 |
Tra2a,Ednrb,Bnip3,Mefv,Il12b,Agrn,Tmem67,Tnfsf10,Acvrl1,Rnf19a,Nck1,Ifna6,Sdc4,Etv5,Pla2g4a,Nampt,Casp8,Cdkn1a,Cacybp,Ifna1,Mlkl,Btg2,Il1b,Pmaip1,Tet2,Polr2g,Trib3,Ifnar1,Tlr3,Prkce,Cdk5r1,Nfkb1,Tnfrsf14,Ppp2r5a,Plek,Lhx2,Bmp2,Acvr1b,Nfkb2,Tnfrsf8,Mid1,Ptpn2,Fzd5,Cebpd,Pdgfrb,Ccl8,Nr1h3,Fosb,Etv6,Ptk2,Rhoq,Ifrd1,S1pr2,Spen,Hspa2,Antxr1,Il15,Csf1,Nupr1,Dnajb2,Gsap,Ccl2,Batf,Nfkbia,Arrdc4,Adrb2,Med21,Mllt6,Birc3,Arid4a,Ifna2,Rbpms,Plekhn1,Eif2ak2,Plagl1,Pnpt1,Stat5a,Map3k8,Rnf139,Tnfrsf1b,Plac8,Scimp,Nlrp3,Zc3hav1,Tlr6,Jak2,Tcea1,Sphk1,Hmgn3,Ddx58,Rictor,Tnfaip3,Irf7,Inhba,Pgk1,Bcl2l11,Peli1,Nr3c1,Cox17,Map2k1,Eif4g2,Stat2,Fpr2,Flt1,Lif,Wdr43,Tnfsf15,Arid5b,Max,Gclc,Pou3f1,Parp3,Dr1,Cd40,Mycl,Mtdh,Icam1,Jmjd6,Kat2b,Irs2,Ikzf1,Angpt1,Il27,Sertad3,Taf4b,Ccl12,Rasgrp1,Atf3,Bambi,Cited2,Tpx2,Il1a,Daxx,Mapkbp1,Plk3,Tnf,Jun,Tcf4,Pcgf5,Fam162a,Mmp9,Sirt1,Ccl22,Lgals9,Acod1,Sqstm1,Spire1,Pbx1,Osm,Cav1,Klf7,Plscr1,Spn,Hsph1,Rapgef2,Rap2c,Adora2b,Casz1,Klf6,Nfil3,Ptgs2,Ier2,Ksr1,Mmd,Bcl9,Irf4,Dtx3l,Med13,Mmp14,Sema4c,Edn1,Fas,Nsd3,Mtcp1,Hmga1,Irf1,Map2k4,Irf2,Ppp1r15b,Il10,Cx3cr1,Cenpe,Hspa1a,Plpp3,Tspo,Il18,Zc3h12a,Ythdf1,Gfi1,Sele,Marco,Hivep2,Casp4,Ldlr,Jarid2,Casp1,Ifna5,Traf2,Nek6,Rnf14,Mul1,Ripk2,Lrp4,Ppp1r15a,Mmp25,Gdf15,Bcl6,Gadd45b,Kdm6b,Il1rn,Txn1,Rgcc,Egr1,Notch2,Met,Myd88,Serp1,Irgm1,Ift57,Zfp281,Fcgr2b,Arid5a,Egr2,Kdr,Nlrc5,Mdfic,Cx3cl1,Kitl,Psme1,Pdgfc,Mdm2,Hmga2,Mapkapk2,Fubp1,Ikbkg,Casp3,Hk2,Psmd10,Nr4a3,Ccnd1,Relb,Pcx,Crlf3,Fbxo4,Prnp,Prdm9,Grk3,Plk2,Thbs1,Ctsc,Rel,Hif1a,Itga5,Psme2,Ccnd2,Il6,Jag1,Cflar,Ciita,Plagl2,Dcp1a,Htr2a,Pde5a,Myc,Zeb1,Ccl9,Rnf19b,Birc2,Csrnp1,Klf2,Aff1,Spry2,Spic,Apaf1,Tlr9,Pf4,Slc9a1,Fcgr1,Scyl2,Ezr,Parp14,Maml2,Cenpj,Vegfc,Dcun1d3,Mecp2,Ccl7,Ell2,Cxcl1,Glipr2,Pou2f2,Optn,Ranbp2,Nlrc4,Stat1,Crkl,Cysltr2,Ripk3,Maff,Trib1,Cycs,Src,Stat3,Egr3,Tnks1bp1,Hcls1,Tfec,Ptafr,Mafg,Klrk1,Pdgfb,Lpar1,Junb,Malt1,Tlr1,Cd74,C3,Fabp3,Nox1,Phip,Psip1,Igf1r,Larp1,Map3k6,Fgr,Ccl5,Ifnb1,Nod1,Jdp2,Pik3r5,Pim2,Eya4,Ccr1,Pml,Ccl4,Syk,Stat4,Sh3bp4,Ccl3,Fzd1,Sod2,Arf4,Hhex,Pik3r6,Irf8,Acsl5,Trim13,Htr2b,Ptch1,Lmo4,Helz2,Clcf1,Ahr,Ncoa7,Tnip1,Lyn,Hspa1b,Fam129a,Tank,Timeless,Cd38,Acsl1,Higd1a,Cd80,Atm,Ankib1,Ahrr,Fos,Zfp36,Gadd45g,Hivep3,Cop1,Stap1,Trim21,Lrp8,Nod2,Plau,Hdac1,Tnfsf4,Plaur,Acvr1,Hinfp,Nr4a1,S100a8,Ets2,Ptger4,Mov10,Atp2b4,Aim2,Irak2,Notch1,Pid1,Uaca,Hmox1,Tlr2,Pim1,Dyrk2,Icosl,Gcnt2,Csf3,Map4k4,Ass1,Tnfsf8,Nmi,Ptprj,Tab2,Nos2,Ifna4,Sesn3,Irgm2,Parp9 |
| 6.612e-40 | -90.21 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_DN | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_DN | 187 | 81 | 15632 | 1249 |
Spint2,Vasp,Car13,Vasn,Inhba,Sh3bp4,Phlda1,Rab10,Cd274,Slfn4,Gdf15,Plek,Cdyl,Ptges,Sec24b,Pf4,Ppp2r2a,Clic4,Slfn3,Cxcl10,Il2rg,Chic2,Adora2b,Rtn1,Rnf19b,Crkl,Rsad2,Ccdc86,Gpr84,Swap70,Timp1,Ddhd1,Apobec3,Plekha5,Parp8,Dync1h1,Tnfaip3,Relb,Tsku,Ifit1,Ube2f,Isg15,Fam133b,Tab2,Mcm10,Ksr1,Ogfr,Lcn2,Rnf14,Lrrc8c,Cd82,Tmem123,Ldlr,Znrf1,Actb,Sema4a,Lyn,Ier3,Kpna3,Mtdh,Parp9,Igsf6,Mmp14,Stard5,Slc44a1,Trip10,D16Ertd472e,Dnaja1,Tspan3,Slc7a11,Syk,Ass1,Morc3,Aff1,Hinfp,Nlrp3,Gmppb,Palld,Usp25,Nfkbiz,Fas |
| 1.075e-39 | -89.73 | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN | 188 | 81 | 15632 | 1249 |
Samsn1,Vps54,Irf7,Osm,Gja1,G3bp2,Stx11,Adora2b,Map3k8,Ptger4,Pcgf5,Slfn9,Sec24a,Slc2a1,Armcx6,Txnrd1,Treml2,Cebpd,Stat3,Gbp4,Gbp9,Stat2,Hif1a,Zfp281,Fam133b,Dtx3l,Socs1,Slc30a4,Prdm1,Hlx,Mxd1,Malt1,Magohb,Lif,Csrnp1,Notch1,Mdfic,Myd88,1600014C10Rik,Sco1,Casp4,Gem,Birc3,Tnfrsf1b,Rnf31,Rnf19a,Xaf1,Rasgrp1,Egln3,Csf1,Ksr1,Plscr1,Zfp36,Odc1,Ifi35,Ppa1,Stat1,Frmd6,Nfil3,Jak2,Asf1a,Cd82,Adam19,D16Ertd472e,Tiparp,Bcl2l11,Parp14,Irgm2,Slfn8,Kat2b,Prnp,P2ry14,Rtp4,Fas,Nfkbiz,Pgs1,Cdkn2d,Mapkapk2,Ahr,Rras2,Zbp1 |
| 1.137e-39 | -89.67 | intracellular part | cellular component | GO:0044424 | 13374 | 1127 | 20747 | 1409 |
Oasl2,Dync1i2,Tmod3,Irf1,Psmb9,Lgals9,Ankrd17,Ldlr,Ampd3,Snn,Vasn,Mafk,Cpd,Bcor,Ccdc88b,Ripk3,Rab20,Wdr59,Arg2,Cxcl14,Pfkl,Agtrap,Mvp,Dse,Sh3bp4,Stx11,Resf1,Arl5b,Batf,Ptges,Yju2,Rbl1,Magohb,Gm12185,Bcl2a1b,Clcn7,Frmd4a,Tnfrsf1b,Prkce,Egr2,Gbp3,Sp110,Rrbp1,Znfx1,Jak2,Ciita,Fam72a,Svbp,Nxf1,Dtx3l,Trim12c,Eno2,Fam129a,Mycl,Plagl2,Irs2,Tab2,Gch1,Marcksl1,Casp4,Rnd1,Rrs1,Hspa2,Stip1,Il1a,Slfn8,AA467197,Sp100,Ctsc,Mx1,Etv5,Ctu1,Snapc1,Brwd3,Lrrc25,Ch25h,Kpna3,Tpi1,Mcm9,Fabp3,Rmdn3,Optn,Tgtp1,Fnbp1l,Rin2,Tapbpl,Fam162a,Phldb1,Fosb,Glipr2,Plek,Zc3hav1,Aff1,Apaf1,Nlrc4,Cox17,Rnf19b,Slc37a3,Sik3,Casp1,Map2k1,Zfp281,Scyl2,P4ha1,Rubcnl,Arid5b,Tgtp2,Nmi,Gsdmd,Larp1,Tfec,Klf3,Fas,Met,Il4i1,Rap1gap2,Tifa,Rai14,Dusp5,Klf6,Intu,Brd2,Phlpp2,Trib1,Fabp7,Adhfe1,Plk3,Rab3ip,Ube2e1,Ccng2,Snx2,B3gnt5,Parp3,Gbp8,Arrdc4,Il6,Bcl2a1d,Hap1,Irf2,Cenpj,Samhd1,Cept1,Jdp2,Fubp1,Nsd3,Psmb8,Glrx,H2-Q6,Akt3,Slc39a4,Slc7a8,Stxbp1,Cpeb4,Dusp14,Setdb2,Plscr1,Tlr6,Notch1,Slc49a4,Rpgrip1l,Slc7a11,Abcc4,Serpinb6b,Gca,Phip,Pdlim7,Nqo1,Sqstm1,Ahr,Parp9,Tcea1,Gbp2,Mapkbp1,Clic5,Acp5,Iigp1,Tmem67,Ifi211,Ifrd1,Aoah,Nfkbil1,Ascc3,Cox18,Ccnd1,Ddhd1,Sertad3,Relb,Ifi205,Rnaset2a,Helz2,Armc8,Mthfd1l,Gsta3,Stard7,4932438A13Rik,Slc48a1,Ppp1r15b,Tbc1d13,Pigv,Smox,Tnfaip2,Dennd1b,Ass1,Rictor,Lpcat2,Hif1a,Slc30a4,Rnf24,Pdss1,Med13,Gcnt2,Oasl1,Hspa1a,Slc31a2,Pkp4,Hilpda,Zcchc2,Tgfbi,Rhof,Fscn1,Rtp4,Il1rn,Arid4a,N4bp1,Rhoq,Rgs14,Mmp13,Lrrc8c,Nlrc5,Pmepa1,Zmynd15,Frmd6,Gmppb,Pim1,Kmo,Fut8,Acsl1,Inpp5b,Gtpbp2,Triobp,Evl,Riox2,Zbp1,Mcm10,Traf5,Ankib1,Acpp,Sav1,Asns,Tshz1,Rnf135,Cd34,Mcm6,Tor1aip2,Aebp2,Birc3,Slc2a1,Fchsd2,Max,Rffl,Ednrb,Srgn,Acp2,Hp,Dnajb2,Tnip1,Slc9a1,Ptgs2,Htr2b,Mamld1,Malt1,Sec24a,Atp11b,Apobec3,Ccl5,Usp18,Rtn1,Mgat1,Arel1,Igtp,Nfkb1,Usp31,Nupr1,Sphk1,Ifit1bl1,Icosl,Marcks,Chst11,Rac3,Serpine1,Dusp6,Prdm9,Slc25a22,Tlr2,Hinfp,Clec5a,Rapgef5,Il15,Pim3,Ifi47,Rtn2,Clic4,Nlrp3,Dnaja1,Bnip3,Odc1,Syne2,Sirt1,Kif9,F830016B08Rik,Dr1,Ptpn2,Selenow,Gng11,Degs2,Filip1l,Dhx58,Rcl1,Chmp4b,Dnase1l3,Wdr43,Slc7a5,Cnp,Trib3,Mpp7,Armcx6,Slfn1,Cdk5r1,Spry2,Gys1,Slc25a37,Csrnp1,Gdf15,Asf1a,Ikbkg,Phf11c,Irf8,Mefv,Maml2,Abtb2,Tmem123,Dtx2,Fbxo4,Vps54,Gng4,Plekha4,Eno1,Dgkh,B4galt4,Atm,Myadm,Prdx1,Mtus1,St3gal5,Keap1,G3bp2,Gsr,Lrch3,Src,Tlr3,Eya4,Upp1,Parp11,Tcf4,Gng12,Prkar2b,Myo1b,Dcp1a,Dyrk2,Dync1h1,Rgs1,Spn,Nod1,Zfp945,Sema4c,Homer1,Nr1h3,Bcl2a1a,Clmp,Ric1,Irak3,Ppp2r5a,D1Ertd622e,Trim26,Mafg,Casz1,Pde3b,Ifit2,Mul1,Sco1,Cutc,Slc39a14,Aftph,Fcgr2b,Pcx,Errfi1,Itgav,Mthfr,Tulp3,Ift22,Phf6,Smg7,Tet2,Gnb4,Stau1,Il1b,Trip13,Gypc,Igf2bp2,Taf4b,Piezo1,Myd88,Pde1b,Nlgn2,Fam53c,Eef1e1,Bmp2,Itpr1,Mosmo,Hmgcs1,Prag1,Sp140,Txn1,Higd1a,Ube2l6,Cmpk2,Mndal,Cacnb3,Gramd1a,Cebpd,Dst,Hk3,Rnf34,Crkl,Cd38,Hlx,Zyx,Tmsb10,Ogfr,Ppp4r2,Peli1,Card6,Ift57,Egr3,Cep350,Ubtd2,Dnaaf3,Ksr1,Plekhg1,Mdfic,Mrpl52,Casp8,Trmt1l,Actb,Cflar,Psme2,Car13,Tlr1,Bcl9,Irak2,Ktn1,Slc31a1,Sgms2,Fam241a,Cst7,Cgas,Tmem178,Gja1,Hmga2,Pnpt1,Pfkfb3,Gm4951,Lap3,Pou3f1,Idi1,Plac8,H2-Q4,Kdm4a,Tmem176b,Cd74,Dusp8,Zfp513,Stat3,Dck,Hk1,Mmd,Atp13a1,Gpr85,Slc44a1,Ppm1k,Lnpk,Ago3,Rbbp8,Pde5a,Cav1,Csrp1,Hmga1,Ust,Arhgef3,Pgm1,Eif2ak2,Pmaip1,Prnp,Plk2,Rbms2,Tlr9,Plpp3,St3gal3,Trim30a,Hk2,Rapgef2,Apba1,Pgk1,Stx6,Lztfl1,Cdc42ep4,Gpc1,Timeless,Tomm70a,Prdx5,Adar,Mt1,Flrt2,Lhx2,Ralgds,Cyfip1,Mmp14,Herc6,Cnot4,Spred1,Ggct,Adgrg6,Katna1,Mid1,Mier3,Sesn3,Wdfy1,Pla2g7,Tent4a,Lrp8,Vasp,Uaca,Prpf38a,Plagl1,Sat1,Spen,Tank,Rbpms,Fmnl2,Tdrd7,Slfn9,Ap3m2,Arhgap26,Sod2,Dusp2,Ppa1,Serp1,Oas1a,Birc2,Csf1,Minpp1,Naa25,Micall2,Ifi44,Smc5,Hopx,P2ry12,Bcl2l11,Ppp1r14b,Morc3,Zhx2,Dbnl,Carmil1,Clcn5,Rabgef1,Ncoa7,Kdr,Jun,Fpr2,Cyth3,Zeb1,Cdyl,Uba7,Spint2,Klf2,Etnk1,Noc4l,P4ha2,Ccdc86,Lif,Pdgfc,Pou2f2,Kdm5b,Swap70,Fos,Esd,Gm5431,Pml,Tasor2,Lox,Tspo,Sele,Ccr3,Cop1,Dtnb,Rnf31,Casp2,Casp7,Sap30,Txnrd1,H2-Eb1,Egln3,Rnf19a,Nkiras1,Egr1,Hsph1,Top3a,Tma16,Zfp40,Igf1r,Tagln,Tbc1d1,Daam1,Ntng2,Mlkl,1600014C10Rik,Phf11b,Dusp1,Ikzf1,Parp12,Fcho2,Bfar,Phactr4,Ifnar1,Phf11a,H2-Ab1,Nmral1,Me1,Shisa3,Nr4a1,Rbms1,Stk40,Kdm6b,Nox1,Ifit1,Cd40,Etv3,Psip1,Spata13,Hhex,Pik3r5,Atf3,Ifit1bl2,Pdgfrb,Gfi1,Gna15,Tal2,Nfkbid,Alas1,Dhrs9,Socs7,Cdkn1a,Sde2,Plcl2,Ak4,Rab19,Bbx,Bambi,Pdgfb,Ahsa1,Lad1,Ccr1,Myo10,Tha1,Lrch1,Ier2,Tpx2,Jarid2,Ubr4,Zc3h12a,Lmo4,Parp14,Acsl5,Oas1b,Tra2a,Ddx4,Irf7,Xaf1,Cited2,Slc4a7,Ubash3b,Atp6v1d,Extl2,Ddx60,Osbpl3,Mapkapk2,Aim2,F11r,Rhoh,Tpst1,Sla,Hspa1b,Lratd2,Slc39a13,Flnb,Psmb10,Sbds,Treml4,Traf1,Nampt,Dnajb4,Irf4,Pcgf5,Nes,Ifitm1,Trim21,Srxn1,Parp10,Cd86,Carhsp1,Tap2,Uchl1,Pttg1,Hivep3,Ell2,Themis2,Pik3r6,Zfp319,Htr2a,H2-Q7,Pid1,Vrk2,Trim56,Pikfyve,Zfp36,Serpinb9,Cers6,Ifi208,Ifi203,Ddit4,Coa5,Lcn2,Pdzd11,Calcrl,Pf4,Tlk2,Ifi35,Mxd1,Gm4841,Dennd6b,Psd,Batf2,9930111J21Rik1,Serpina3g,Zup1,Agrn,Ccnd2,Mt2,Fndc3a,Fpr1,P2ry2,Psma6,Pik3cd,Ep400,Rnf114,Dek,Plaat3,Dpy19l1,St3gal6,Edn1,Dennd2a,Tent2,Hcls1,Cdkn2d,Cenpe,Palld,Shfl,Olr1,Itpkc,Spic,Rel,Dgka,Ppp2r1b,Hck,Nfkbib,Il12b,Cd164,Phlpp1,Ranbp2,Stat2,4930453N24Rik,Eif4g2,Stat5a,Ccrl2,Tnfaip3,Kif3c,Tnf,Ppp2r2a,Trim12a,Mdm2,Gbgt1,Rilpl1,Atp10a,Usp12,Nr4a3,Lipe,Klf7,Hsd17b12,Aldh1b1,Rnf145,Ets2,Trip10,Serpinb9b,Dcun1d3,Gclm,Nos2,Usp25,Ero1l,Notch2,Ptger4,Dram1,Ahrr,Polr2g,Nfkb2,Psmd10,Ptk2,Pnp2,Tor1aip1,Fgr,Mtdh,Dach1,Herc3,Rcan1,Adam19,Samd9l,Gbp2b,Tuba4a,Atp11a,Golga3,Ifih1,Hivep2,Ythdf1,Dusp4,Cacna1d,Rnf139,Ppp6r1,Map3k8,Ifi214,Mdn1,Klhl25,Cx3cr1,Flrt3,Fam111a,Psmb6,Cdyl2,Junb,Fignl2,Klf8,Vcpip1,Casp3,Oas2,Rhou,Rhbdf2,Plod2,Wars,Marf1,Grk3,Dcp2,Tle3,Dmxl2,Nt5c3,Phlda1,Ppp1r15a,Acod1,Znrf1,Samsn1,Spsb1,Hmgn3,Rgcc,Bcorl1,Slc29a3,Gbp9,Ifi204,Chic2,Fam20c,Rab11fip1,Radx,Atp2b4,Abr,Gk,Kmt5a,Mark2,Zfp800,Sh3bgrl2,Ifit3,Noct,Stap1,Trim14,Pde4b,Arf4,Xrn1,Hdc,Mthfd2,Plekha5,Slc16a3,Cd14,Jmjd6,Mtmr14,Kif5c,F10,Hdac1,Tyk2,Slc25a12,9130023H24Rik,Rap2c,Traf2,Slfn5,Gpsm2,Ier3,Asap3,Asah2,Ifit3b,Dmwd,Nfkbiz,Marco,Nr3c1,Maff,Cd302,Ccl2,Hsd17b7,Mx2,Map2k4,P2ry13,Ccnj,Crbn,Pdk3,Prpf4,Lpar1,Tnks1bp1,Arid5a,Zswim4,Mov10,Sema4a,Gadd45b,Il15ra,Nfil3,Thbs1,Pdpn,Plod3,Phyh,Usb1,Ciapin1,Rnf14,Stxbp3,Ifi207,Rab32,Sgcb,Lipg,Gadd45g,Myc,Mtcp1,Il18,Map4k4,Ppfia3,Rgs3,Ociad1,Cycs,Snx10,Lacc1,Mecp2,Rnd3,Cnn2,Pgs1,Stoml1,Ifi209,Plat,Nfxl1,Prdm1,S100a8,Arl5c,Mtfr2,Rab9,Cdc42ep2,Slc15a3,H2-Aa,Spire1,Tmtc2,Itga5,Cnn3,Trim36,Ddx58,Mppe1,Slc30a1,H3f3b,Oas3,Serpinb2,Ccne1,Socs3,Rcn1,Abcc5,Ldha,Sinhcaf,Pbx1,Dnaja2,Slamf7,Rhoc,Etv6,Plekhf2,Msr1,Tgs1,Nat2,Rims3,Trim13,Sass6,Ppp2r3a,Kitl,Pgap2,Chd9,Nod2,Rsad2,Irgm1,Cep85l,Cx3cl1,Plekhn1,Rab21,Nfkbia,Dock4,Tut7,Acvr1b,Ppp1r12b,Kat2b,Mfap3l,Ezr,Lcp2,Milr1,Vezt,Tiparp,Mcmbp,Ikbke,Adap2,Cd274,Agpat4,Adora2a,Rfx5,Nck1,Rab10,Psat1,Ext1,Pla2g4a,Sgk3,Stat4,Ap3b1,Phf11d,Gbp7,Hmox1,Stat1,Crlf3,Rasgrp1,Mcoln2,Trim34a,Lnpep,Ptgir,Ptch1,Nfkbie,Procr,Med21,Nek6,Isg15,Grina,Rnaset2b,Lyn,Daxx,Sec24b,Gpd2,Sdc4,Prkx,Abcc1,Slc16a1,Azi2,Rars,Inhba,Flt1,Caml,Zbtb5,Syk,Ripk2,Tpm4,Slc25a25,Htra1,Gem,Sipa1l1,Tap1,Adrb2,Pstpip2,Gclc,Tor3a,Ifi213,Ehd1,St3gal1,Psme1,Perm1,Dock10,Gsap,Socs1,Btg2,Arl4a,Kcnj2,Bcl6,Tapbp,Fzd5,Mitd1,Hat1,Vcam1,Oas1g,Cacybp,Pim2,Aida,Ncoa5,Dusp16,Whamm,Foxp4,Rsbn1,Isg20,Anp32a,Irgm2,Gpr18,Plekha2 |
| 1.137e-39 | -89.67 | intracellular | cellular component | GO:0005622 | 13374 | 1127 | 20747 | 1409 |
Gbp2b,Samd9l,Psmd10,Pnp2,Tor1aip1,Ptk2,Nfkb2,Polr2g,Adam19,Dach1,Herc3,Rcan1,Fgr,Mtdh,Cacna1d,Rnf139,Dusp4,Tuba4a,Atp11a,Golga3,Hivep2,Ythdf1,Ifih1,Ets2,Rnf145,Hsd17b12,Aldh1b1,Notch2,Ptger4,Dram1,Ahrr,Trip10,Serpinb9b,Dcun1d3,Nos2,Gclm,Ero1l,Usp25,Kif3c,Trim12a,Ppp2r2a,Tnf,Tnfaip3,Ccrl2,Nr4a3,Lipe,Klf7,Mdm2,Gbgt1,Usp12,Atp10a,Rilpl1,Ppp2r1b,Hck,Nfkbib,Il12b,Itpkc,Shfl,Olr1,Dgka,Spic,Rel,Stat2,4930453N24Rik,Eif4g2,Stat5a,Phlpp1,Cd164,Ranbp2,St3gal6,Edn1,Dennd2a,Tent2,Plaat3,Rnf114,Dek,Dpy19l1,Cenpe,Palld,Cdkn2d,Hcls1,Agrn,Ccnd2,Zup1,Serpina3g,Psma6,P2ry2,Ep400,Pik3cd,Fndc3a,Mt2,Fpr1,Zfp36,Cers6,Serpinb9,Ifi208,Ddit4,Coa5,Lcn2,Ifi203,Vrk2,Pikfyve,Trim56,Htr2a,H2-Q7,Pid1,Gm4841,9930111J21Rik1,Dennd6b,Batf2,Psd,Tlk2,Ifi35,Pdzd11,Calcrl,Pf4,Mxd1,Tap2,Carhsp1,Cd86,Srxn1,Trim21,Parp10,Themis2,Pik3r6,Ell2,Hivep3,Zfp319,Pttg1,Uchl1,Flnb,Hspa1b,Slc39a13,Lratd2,Nes,Pcgf5,Ifitm1,Sbds,Treml4,Psmb10,Irf4,Nampt,Dnajb4,Traf1,Slc4a7,Ubash3b,Xaf1,Cited2,Tra2a,Ddx4,Irf7,Aim2,Tpst1,Rhoh,Sla,F11r,Extl2,Atp6v1d,Ddx60,Mapkapk2,Osbpl3,Pdgfb,Ahsa1,Myo10,Lad1,Ccr1,Rab19,Bbx,Bambi,Ubr4,Zc3h12a,Lmo4,Jarid2,Parp14,Acsl5,Oas1b,Lrch1,Tha1,Tpx2,Ier2,Pik3r5,Ifit1bl2,Gfi1,Pdgfrb,Atf3,Etv3,Psip1,Cd40,Spata13,Hhex,Socs7,Dhrs9,Cdkn1a,Ak4,Plcl2,Sde2,Gna15,Tal2,Nfkbid,Alas1,Parp12,Ikzf1,Phf11a,H2-Ab1,Fcho2,Phactr4,Bfar,Ifnar1,Dusp1,Phf11b,Kdm6b,Stk40,Nox1,Ifit1,Me1,Nmral1,Nr4a1,Rbms1,Shisa3,Rnf19a,Egr1,Nkiras1,Sap30,Egln3,Txnrd1,H2-Eb1,Ntng2,Daam1,Zfp40,Tma16,Tbc1d1,Igf1r,Tagln,1600014C10Rik,Mlkl,Hsph1,Top3a,Esd,Fos,Gm5431,Tasor2,Lox,Tspo,Pml,Kdm5b,Swap70,Pdgfc,Pou2f2,Casp7,Ccr3,Sele,Cop1,Casp2,Dtnb,Rnf31,Etnk1,Cdyl,Uba7,Spint2,Klf2,P4ha2,Noc4l,Jun,Fpr2,Cyth3,Zeb1,Lif,Ccdc86,Dusp16,Ncoa5,Aida,Isg20,Anp32a,Rsbn1,Plekha2,Irgm2,Gpr18,Foxp4,Whamm,Dock10,Gsap,Socs1,Ehd1,Ifi213,St3gal1,Tor3a,Perm1,Psme1,Mitd1,Fzd5,Cacybp,Pim2,Vcam1,Hat1,Oas1g,Arl4a,Btg2,Tapbp,Kcnj2,Bcl6,Rars,Syk,Ripk2,Inhba,Zbtb5,Flt1,Caml,Abcc1,Prkx,Slc16a1,Azi2,Tap1,Adrb2,Gclc,Pstpip2,Htra1,Slc25a25,Tpm4,Sipa1l1,Gem,Phf11d,Hmox1,Gbp7,Stat1,Sgk3,Ap3b1,Stat4,Ext1,Pla2g4a,Nfkbie,Ptch1,Procr,Med21,Nek6,Ptgir,Lnpep,Grina,Rnaset2b,Lyn,Daxx,Sec24b,Gpd2,Sdc4,Isg15,Rasgrp1,Crlf3,Trim34a,Mcoln2,Ezr,Vezt,Tiparp,Lcp2,Milr1,Nck1,Psat1,Rab10,Ikbke,Adap2,Mcmbp,Adora2a,Rfx5,Cd274,Agpat4,Sass6,Trim13,Ppp2r3a,Nat2,Rims3,Kitl,Pgap2,Plekhf2,Etv6,Msr1,Tgs1,Ppp1r12b,Tut7,Acvr1b,Kat2b,Mfap3l,Rsad2,Cep85l,Irgm1,Cx3cl1,Chd9,Nod2,Nfkbia,Dock4,Plekhn1,Rab21,Mppe1,Ddx58,Serpinb2,H3f3b,Slc30a1,Oas3,Itga5,Cnn3,Trim36,Sinhcaf,Ldha,Dnaja2,Pbx1,Slamf7,Rhoc,Ccne1,Socs3,Abcc5,Rcn1,Slc15a3,Mtfr2,Rab9,Cdc42ep2,H2-Aa,Prdm1,Nfxl1,Arl5c,S100a8,Spire1,Tmtc2,Snx10,Lacc1,Rgs3,Ppfia3,Ociad1,Cycs,Plat,Rnd3,Pgs1,Cnn2,Mecp2,Ifi209,Stoml1,Thbs1,Nfil3,Pdpn,Mov10,Tnks1bp1,Zswim4,Arid5a,Gadd45b,Il15ra,Sema4a,Gadd45g,Rab32,Sgcb,Lipg,Map4k4,Il18,Mtcp1,Myc,Phyh,Plod3,Stxbp3,Ifi207,Usb1,Ciapin1,Rnf14,Dmwd,Nr3c1,Maff,Nfkbiz,Marco,Ier3,Slfn5,Gpsm2,Ifit3b,Asah2,Asap3,Crbn,P2ry13,Map2k4,Ccnj,Lpar1,Prpf4,Pdk3,Cd302,Ccl2,Hsd17b7,Mx2,9130023H24Rik,Kif5c,Hdac1,F10,Slc25a12,Tyk2,Rap2c,Traf2,Pde4b,Arf4,Trim14,Xrn1,Mark2,Noct,Stap1,Zfp800,Sh3bgrl2,Ifit3,Jmjd6,Mtmr14,Slc16a3,Plekha5,Mthfd2,Hdc,Cd14,Rgcc,Ifi204,Slc29a3,Bcorl1,Gbp9,Znrf1,Samsn1,Acod1,Hmgn3,Spsb1,Atp2b4,Abr,Radx,Rab11fip1,Kmt5a,Gk,Fam20c,Chic2,Rhbdf2,Wars,Plod2,Marf1,Grk3,Rhou,Casp3,Oas2,Vcpip1,Nt5c3,Phlda1,Ppp1r15a,Tle3,Dmxl2,Dcp2,Fam111a,Cx3cr1,Klhl25,Flrt3,Psmb6,Ppp6r1,Map3k8,Ifi214,Mdn1,Fignl2,Klf8,Cdyl2,Junb,Usp18,Rtn1,Mgat1,Ccl5,Usp31,Nfkb1,Nupr1,Igtp,Arel1,Malt1,Mamld1,Htr2b,Sec24a,Apobec3,Atp11b,Slc25a22,Prdm9,Hinfp,Tlr2,Sphk1,Ifit1bl1,Dusp6,Rac3,Chst11,Icosl,Marcks,Serpine1,Max,Ednrb,Rffl,Acp2,Srgn,Tor1aip2,Mcm6,Aebp2,Cd34,Slc2a1,Birc3,Fchsd2,Ptgs2,Slc9a1,Hp,Tnip1,Dnajb2,Inpp5b,Triobp,Gtpbp2,Acsl1,Fut8,Acpp,Sav1,Asns,Traf5,Ankib1,Tshz1,Rnf135,Evl,Zbp1,Riox2,Mcm10,N4bp1,Rhoq,Il1rn,Rtp4,Arid4a,Lrrc8c,Mmp13,Rgs14,Tgfbi,Rhof,Fscn1,Gmppb,Frmd6,Pim1,Kmo,Nlrc5,Zmynd15,Pmepa1,Lpcat2,Slc30a4,Hif1a,Tnfaip2,Smox,Pigv,Dennd1b,Ass1,Rictor,Slc31a2,Hspa1a,Pkp4,Oasl1,Hilpda,Zcchc2,Pdss1,Rnf24,Gcnt2,Med13,Sertad3,Relb,Ddhd1,Helz2,Armc8,Ifi205,Rnaset2a,Cox18,Aoah,Nfkbil1,Ascc3,Ccnd1,4932438A13Rik,Stard7,Tbc1d13,Slc48a1,Ppp1r15b,Mthfd1l,Gsta3,Ahr,Parp9,Gbp2,Tcea1,Nqo1,Pdlim7,Sqstm1,Ifi211,Ifrd1,Clic5,Mapkbp1,Iigp1,Tmem67,Acp5,Cpeb4,Stxbp1,Slc7a8,Dusp14,Slc39a4,Glrx,H2-Q6,Akt3,Notch1,Rpgrip1l,Slc49a4,Slc7a11,Phip,Abcc4,Serpinb6b,Gca,Setdb2,Plscr1,Tlr6,B3gnt5,Ccng2,Snx2,Parp3,Rab3ip,Ube2e1,Adhfe1,Plk3,Samhd1,Cenpj,Hap1,Irf2,Psmb8,Jdp2,Cept1,Fubp1,Nsd3,Gbp8,Arrdc4,Bcl2a1d,Il6,Il4i1,Fas,Klf3,Met,Tifa,Rai14,Rap1gap2,Arid5b,Tgtp2,Nmi,Larp1,Tfec,Gsdmd,Phlpp2,Trib1,Fabp7,Dusp5,Klf6,Brd2,Intu,Slc37a3,Sik3,Map2k1,Zfp281,Casp1,Cox17,Rnf19b,Rubcnl,P4ha1,Scyl2,Rin2,Fnbp1l,Optn,Rmdn3,Tgtp1,Tapbpl,Tpi1,Kpna3,Fabp3,Mcm9,Aff1,Glipr2,Zc3hav1,Plek,Nlrc4,Apaf1,Fam162a,Fosb,Phldb1,AA467197,Ctsc,Sp100,Ctu1,Etv5,Mx1,Il1a,Stip1,Slfn8,Lrrc25,Ch25h,Snapc1,Brwd3,Ciita,Fam72a,Dtx3l,Svbp,Trim12c,Eno2,Nxf1,Gbp3,Sp110,Tnfrsf1b,Prkce,Egr2,Jak2,Rrbp1,Znfx1,Rrs1,Rnd1,Hspa2,Plagl2,Irs2,Tab2,Fam129a,Mycl,Marcksl1,Casp4,Gch1,Stx11,Resf1,Dse,Sh3bp4,Arl5b,Batf,Agtrap,Pfkl,Cxcl14,Mvp,Gm12185,Bcl2a1b,Frmd4a,Clcn7,Rbl1,Magohb,Ptges,Yju2,Ampd3,Ldlr,Irf1,Tmod3,Oasl2,Dync1i2,Lgals9,Ankrd17,Psmb9,Ccdc88b,Bcor,Ripk3,Wdr59,Arg2,Rab20,Snn,Cpd,Mafk,Vasn,Bcl2l11,Morc3,Zhx2,Ppp1r14b,P2ry12,Clcn5,Rabgef1,Kdr,Ncoa7,Carmil1,Dbnl,Sod2,Dusp2,Serp1,Ppa1,Slfn9,Arhgap26,Ap3m2,Ifi44,Micall2,Smc5,Minpp1,Naa25,Hopx,Csf1,Birc2,Oas1a,Pla2g7,Katna1,Wdfy1,Mid1,Sesn3,Mier3,Rbpms,Tdrd7,Fmnl2,Vasp,Uaca,Prpf38a,Tent4a,Lrp8,Spen,Sat1,Tank,Plagl1,Stx6,Lztfl1,Pgk1,Adar,Prdx5,Mt1,Flrt2,Timeless,Cdc42ep4,Gpc1,Tomm70a,Hk2,Trim30a,Apba1,Rapgef2,Cnot4,Mmp14,Herc6,Adgrg6,Ggct,Spred1,Lhx2,Cyfip1,Ralgds,Pgm1,Prnp,Eif2ak2,Pmaip1,Ust,Hmga1,Arhgef3,St3gal3,Plk2,Plpp3,Tlr9,Rbms2,Hk1,Stat3,Dck,Pde5a,Rbbp8,Ago3,Csrp1,Cav1,Mmd,Atp13a1,Ppm1k,Lnpk,Gpr85,Slc44a1,Hmga2,Lap3,Pou3f1,Pnpt1,Gm4951,Pfkfb3,Cst7,Cgas,Tmem178,Gja1,Dusp8,Cd74,Zfp513,Kdm4a,Tmem176b,Idi1,H2-Q4,Plac8,Cflar,Psme2,Irak2,Ktn1,Bcl9,Tlr1,Car13,Ksr1,Plekhg1,Trmt1l,Actb,Mrpl52,Mdfic,Casp8,Fam241a,Sgms2,Slc31a1,Cd38,Rnf34,Crkl,Hlx,Ogfr,Zyx,Tmsb10,Dst,Hk3,Cep350,Ubtd2,Dnaaf3,Peli1,Ppp4r2,Egr3,Card6,Ift57,Pde1b,Nlgn2,Taf4b,Myd88,Piezo1,Itpr1,Mosmo,Hmgcs1,Fam53c,Bmp2,Eef1e1,Igf2bp2,Cacnb3,Mndal,Ube2l6,Cmpk2,Cebpd,Gramd1a,Prag1,Higd1a,Txn1,Sp140,Cutc,Aftph,Slc39a14,Fcgr2b,Mafg,Casz1,Sco1,Pde3b,Ifit2,Mul1,Stau1,Gnb4,Gypc,Trip13,Il1b,Itgav,Mthfr,Tulp3,Ift22,Phf6,Errfi1,Pcx,Tet2,Smg7,Bcl2a1a,Homer1,Sema4c,Zfp945,Nr1h3,Irak3,Ppp2r5a,Trim26,D1Ertd622e,Ric1,Clmp,Tlr3,Eya4,St3gal5,Keap1,G3bp2,Lrch3,Gsr,Src,Rgs1,Dync1h1,Dyrk2,Nod1,Spn,Gng12,Prkar2b,Parp11,Upp1,Tcf4,Dcp1a,Myo1b,Irf8,Mefv,Phf11c,Abtb2,Maml2,Tmem123,Asf1a,Gdf15,Ikbkg,B4galt4,Atm,Plekha4,Dgkh,Eno1,Prdx1,Mtus1,Myadm,Dtx2,Gng4,Fbxo4,Vps54,Filip1l,Degs2,Gng11,Dhx58,Rcl1,Kif9,F830016B08Rik,Dr1,Ptpn2,Selenow,Slfn1,Cdk5r1,Spry2,Gys1,Csrnp1,Slc25a37,Slc7a5,Cnp,Trib3,Dnase1l3,Chmp4b,Wdr43,Armcx6,Mpp7,Ifi47,Pim3,Rtn2,Clic4,Rapgef5,Clec5a,Il15,Sirt1,Syne2,Dnaja1,Bnip3,Nlrp3,Odc1 |
| 1.158e-39 | -89.65 | regulation of protein phosphorylation | biological process | GO:0001932 | 1437 | 237 | 20694 | 1406 |
Tnks1bp1,Src,Fpr2,Stat2,Hcls1,Map2k1,Pdgfb,Lif,Flt1,Lpar1,Tnfsf15,Rgs14,Scimp,Sphk1,Crkl,Tlr6,Jak2,Errfi1,Trib1,Tnfaip3,Inhba,Rictor,Adar,Cysltr2,Ripk3,Fcgr1,Tlr9,Adrb2,Ccl2,Parp14,Ezr,Ddit4,Vegfc,Rbpms,Ifna2,Socs3,Map3k8,Glipr2,Socs1,Eif2ak2,Ccl7,Slfn1,Pde5a,Ccl8,Htr2a,Fzd5,Ptpn2,Pdgfrb,Ptk2,Ccl9,Hspa2,S1pr2,Dusp16,Ccng2,Spry2,Csf1,Il15,Thbs1,Grk3,Prnp,Bmp2,Il6,Ccnd2,Dusp1,Acvr1b,Itga5,Cflar,Dusp8,Mid1,Lox,Mlkl,Ifna1,Pdgfc,Trib3,Il1b,Tlr3,Casp3,Ifnar1,Ikbkg,Tnfrsf14,Ppp2r5a,Ccnd1,Prkce,Psmd10,Cdk5r1,Nck1,Ifna6,Acvrl1,Met,Myd88,Cdkn1a,Fcgr2b,Sdc4,Ubash3b,Kdr,Dusp6,Kitl,Cx3cl1,Mdfic,Dusp4,Gdf15,Samsn1,Ppp1r15a,Ednrb,Il1rn,Txn1,Agrn,Il12b,Gadd45b,Spred3,Notch2,Pmepa1,Egr1,Rgcc,Map4k4,Gcnt2,Csf3,Ccne1,Ptprj,Nek6,Spred1,Traf2,Ifna5,Parp9,Mul1,Ripk2,Lrp4,Stk40,Ifna4,Irgm2,Tab2,Gbp4,Mvp,Irak2,Zc3h12a,Il18,Pid1,Notch1,Marco,Pim1,Tlr2,Hdac1,Phlpp1,Irf1,Cx3cr1,Plaur,Acvr1,Ppp1r15b,Map2k4,Plpp3,Ptger4,Atp2b4,Cenpe,Bst1,Adora2a,Irak3,Gadd45g,Dnaja1,Prkar2b,Stap1,Edn1,Sema4c,Mtcp1,Nod2,Lrp8,Fas,Hsph1,Rapgef2,Fam72a,Spn,Fam129a,Dusp5,Rap2c,Dusp2,Atm,Cd80,Higd1a,Acsl1,Mmd,Ksr1,Ptgs2,Plcl2,Ccl22,Sirt1,Mmp9,Lgals9,Pik3r6,Hhex,Sqstm1,Htr2b,Cav1,Lyn,Osm,Tnip1,Myadm,Clcf1,Pik3r5,Prdx1,Angpt1,Atf3,Ccr1,Pml,Ccl12,Ccnj,Rasgrp1,Tpx2,Syk,Ccl4,Jun,Fzd1,Tnf,Mapkbp1,Il1a,Daxx,Ccl3,Aida,Malt1,Actb,Cd74,C3,Tlr1,Map3k6,Fgr,Vrk2,Cd40,Igf1r,Phip,Wars,Nox1,Uchl1,Nod1,Ifnb1,Cdkn2d,Kat2b,Rabgef1,Ccl5,Icam1 |
| 1.183e-39 | -89.63 | cytoplasm | cellular component | GO:0005737 | 10716 | 963 | 20747 | 1409 |
Slc25a22,Tlr2,Sphk1,Ifit1bl1,Serpine1,Chst11,Rac3,Marcks,Icosl,Dusp6,Ccl5,Rtn1,Mgat1,Usp18,Igtp,Arel1,Nupr1,Nfkb1,Htr2b,Malt1,Atp11b,Apobec3,Sec24a,Slc9a1,Ptgs2,Hp,Dnajb2,Tnip1,Rffl,Max,Srgn,Acp2,Cd34,Tor1aip2,Fchsd2,Slc2a1,Birc3,Ankib1,Traf5,Asns,Sav1,Acpp,Rnf135,Evl,Zbp1,Riox2,Inpp5b,Triobp,Fut8,Acsl1,Frmd6,Gmppb,Kmo,Pim1,Nlrc5,Pmepa1,Zmynd15,Arid4a,Rtp4,Il1rn,Rhoq,Mmp13,Rgs14,Lrrc8c,Rhof,Fscn1,Tgfbi,Oasl1,Pkp4,Slc31a2,Hspa1a,Zcchc2,Hilpda,Rnf24,Pdss1,Gcnt2,Lpcat2,Hif1a,Slc30a4,Pigv,Tnfaip2,Smox,Dennd1b,Ass1,Stard7,Ppp1r15b,Slc48a1,Tbc1d13,Gsta3,Mthfd1l,Ddhd1,Relb,Sertad3,Rnaset2a,Ifi205,Armc8,Helz2,Ascc3,Nfkbil1,Aoah,Cox18,Ccnd1,Ifi211,Ifrd1,Mapkbp1,Clic5,Acp5,Tmem67,Iigp1,Parp9,Ahr,Gbp2,Pdlim7,Nqo1,Sqstm1,Slc7a11,Slc49a4,Rpgrip1l,Notch1,Gca,Serpinb6b,Abcc4,Setdb2,Tlr6,Plscr1,Slc7a8,Cpeb4,Stxbp1,Dusp14,H2-Q6,Akt3,Glrx,Slc39a4,Irf2,Hap1,Cenpj,Cept1,Psmb8,Il6,Bcl2a1d,Arrdc4,Gbp8,Snx2,Ccng2,B3gnt5,Parp3,Plk3,Adhfe1,Rab3ip,Phlpp2,Fabp7,Trib1,Dusp5,Klf6,Intu,Brd2,Met,Fas,Il4i1,Rap1gap2,Rai14,Tifa,Nmi,Tgtp2,Gsdmd,Larp1,P4ha1,Scyl2,Rubcnl,Slc37a3,Sik3,Casp1,Map2k1,Rnf19b,Cox17,Zc3hav1,Plek,Glipr2,Apaf1,Nlrc4,Fam162a,Phldb1,Optn,Tgtp1,Rmdn3,Rin2,Fnbp1l,Tapbpl,Kpna3,Tpi1,Fabp3,Ch25h,Lrrc25,Sp100,Ctsc,AA467197,Mx1,Ctu1,Il1a,Stip1,Slfn8,Rnd1,Rrs1,Hspa2,Fam129a,Irs2,Tab2,Gch1,Marcksl1,Casp4,Fam72a,Svbp,Eno2,Dtx3l,Trim12c,Nxf1,Egr2,Prkce,Tnfrsf1b,Gbp3,Rrbp1,Jak2,Bcl2a1b,Gm12185,Clcn7,Frmd4a,Ptges,Dse,Sh3bp4,Resf1,Stx11,Batf,Arl5b,Cxcl14,Agtrap,Pfkl,Mvp,Ripk3,Ccdc88b,Rab20,Wdr59,Arg2,Snn,Vasn,Cpd,Ldlr,Ampd3,Oasl2,Dync1i2,Tmod3,Irf1,Psmb9,Ankrd17,Lgals9,Rabgef1,Clcn5,Kdr,Carmil1,Dbnl,Bcl2l11,Ppp1r14b,Zhx2,P2ry12,Naa25,Minpp1,Ifi44,Micall2,Hopx,Oas1a,Csf1,Birc2,Sod2,Serp1,Ppa1,Dusp2,Slfn9,Ap3m2,Arhgap26,Rbpms,Fmnl2,Tdrd7,Tent4a,Vasp,Uaca,Plagl1,Tank,Sat1,Pla2g7,Katna1,Sesn3,Mid1,Wdfy1,Herc6,Mmp14,Cnot4,Spred1,Ggct,Adgrg6,Ralgds,Cyfip1,Pgk1,Lztfl1,Stx6,Tomm70a,Gpc1,Cdc42ep4,Mt1,Flrt2,Prdx5,Adar,Trim30a,Hk2,Rapgef2,Apba1,St3gal3,Plk2,Rbms2,Tlr9,Plpp3,Pgm1,Eif2ak2,Pmaip1,Prnp,Ust,Arhgef3,Ago3,Pde5a,Cav1,Csrp1,Mmd,Atp13a1,Slc44a1,Gpr85,Lnpk,Ppm1k,Hk1,Stat3,Dck,Kdm4a,Cd74,Dusp8,Idi1,H2-Q4,Pfkfb3,Gm4951,Pnpt1,Lap3,Cgas,Tmem178,Cst7,Gja1,Fam241a,Sgms2,Slc31a1,Psme2,Cflar,Tlr1,Car13,Irak2,Ktn1,Bcl9,Ksr1,Casp8,Mrpl52,Mdfic,Actb,Ubtd2,Cep350,Dnaaf3,Ppp4r2,Ift57,Card6,Crkl,Cd38,Rnf34,Tmsb10,Zyx,Ogfr,Dst,Hk3,Cmpk2,Cacnb3,Mndal,Gramd1a,Prag1,Sp140,Higd1a,Txn1,Piezo1,Myd88,Taf4b,Nlgn2,Pde1b,Eef1e1,Bmp2,Mosmo,Hmgcs1,Itpr1,Igf2bp2,Stau1,Il1b,Gypc,Pcx,Errfi1,Itgav,Mthfr,Tulp3,Smg7,Cutc,Fcgr2b,Aftph,Slc39a14,Casz1,Mul1,Ifit2,Pde3b,Sco1,Ppp2r5a,Irak3,D1Ertd622e,Trim26,Clmp,Ric1,Bcl2a1a,Sema4c,Homer1,Nr1h3,Dyrk2,Dync1h1,Rgs1,Nod1,Upp1,Gng12,Prkar2b,Myo1b,Dcp1a,Eya4,Tlr3,Keap1,St3gal5,Lrch3,Gsr,Src,G3bp2,Eno1,Plekha4,Dgkh,Atm,B4galt4,Myadm,Mtus1,Prdx1,Dtx2,Fbxo4,Vps54,Gng4,Mefv,Irf8,Tmem123,Gdf15,Ikbkg,Spry2,Slfn1,Cdk5r1,Slc25a37,Gys1,Chmp4b,Dnase1l3,Cnp,Slc7a5,Armcx6,Gng11,Degs2,Filip1l,Dhx58,F830016B08Rik,Kif9,Ptpn2,Selenow,Syne2,Sirt1,Nlrp3,Bnip3,Dnaja1,Odc1,Pim3,Ifi47,Rtn2,Clic4,Clec5a,Il15,Dusp4,Cacna1d,Rnf139,Golga3,Atp11a,Tuba4a,Ifih1,Ythdf1,Samd9l,Gbp2b,Nfkb2,Polr2g,Ptk2,Pnp2,Psmd10,Mtdh,Fgr,Rcan1,Adam19,Herc3,Dach1,Notch2,Ahrr,Dram1,Dcun1d3,Serpinb9b,Trip10,Ero1l,Usp25,Nos2,Gclm,Rnf145,Ets2,Aldh1b1,Hsd17b12,Lipe,Gbgt1,Mdm2,Rilpl1,Atp10a,Usp12,Kif3c,Tnf,Trim12a,Ppp2r2a,Ccrl2,Tnfaip3,Stat2,Stat5a,Eif4g2,Cd164,Phlpp1,Ranbp2,Ppp2r1b,Il12b,Hck,Nfkbib,Shfl,Itpkc,Rel,Dgka,Palld,Cenpe,Hcls1,Cdkn2d,Dennd2a,Edn1,St3gal6,Tent2,Dek,Rnf114,Plaat3,P2ry2,Psma6,Pik3cd,Mt2,Fndc3a,Fpr1,Zup1,Ccnd2,Agrn,Serpina3g,Gm4841,Psd,Dennd6b,9930111J21Rik1,Pf4,Calcrl,Pdzd11,Tlk2,Mxd1,Serpinb9,Ifi208,Cers6,Zfp36,Ifi203,Lcn2,Coa5,Ddit4,Pid1,Htr2a,H2-Q7,Pikfyve,Trim56,Vrk2,Hivep3,Pik3r6,Themis2,Uchl1,Pttg1,Carhsp1,Tap2,Trim21,Srxn1,Parp10,Nes,Ifitm1,Psmb10,Treml4,Sbds,Traf1,Dnajb4,Nampt,Flnb,Hspa1b,Lratd2,Slc39a13,Aim2,F11r,Sla,Tpst1,Rhoh,Extl2,Osbpl3,Mapkapk2,Ddx60,Cited2,Xaf1,Slc4a7,Ubash3b,Ddx4,Irf7,Jarid2,Zc3h12a,Ubr4,Oas1b,Acsl5,Parp14,Tha1,Lrch1,Tpx2,Ier2,Ahsa1,Pdgfb,Ccr1,Myo10,Rab19,Bambi,Bbx,Cdkn1a,Socs7,Dhrs9,Plcl2,Ak4,Alas1,Pik3r5,Pdgfrb,Ifit1bl2,Cd40,Spata13,Hhex,Stk40,Ifit1,Nox1,Nmral1,Me1,Shisa3,Rbms1,Nr4a1,Ikzf1,Bfar,Ifnar1,Phactr4,Fcho2,H2-Ab1,Dusp1,Igf1r,Tagln,Ntng2,Daam1,Mlkl,1600014C10Rik,Hsph1,Top3a,Rnf19a,Nkiras1,Egr1,H2-Eb1,Txnrd1,Egln3,Casp7,Cop1,Ccr3,Sele,Dtnb,Rnf31,Casp2,Fos,Gm5431,Esd,Tspo,Pml,Tasor2,Pou2f2,Pdgfc,Swap70,Kdm5b,Lif,Uba7,Spint2,Etnk1,P4ha2,Fpr2,Jun,Cyth3,Zeb1,Anp32a,Isg20,Gpr18,Irgm2,Plekha2,Whamm,Dusp16,Aida,Mitd1,Fzd5,Oas1g,Vcam1,Pim2,Cacybp,Btg2,Arl4a,Bcl6,Kcnj2,Tapbp,Dock10,Socs1,Gsap,Tor3a,St3gal1,Ifi213,Ehd1,Psme1,Perm1,Tap1,Gclc,Pstpip2,Adrb2,Tpm4,Slc25a25,Htra1,Sipa1l1,Rars,Caml,Flt1,Inhba,Ripk2,Syk,Slc16a1,Prkx,Abcc1,Azi2,Lnpep,Ptgir,Nek6,Procr,Ptch1,Nfkbie,Isg15,Gpd2,Sdc4,Daxx,Sec24b,Lyn,Grina,Rnaset2b,Crlf3,Rasgrp1,Mcoln2,Trim34a,Gbp7,Hmox1,Stat1,Pla2g4a,Ext1,Stat4,Ap3b1,Sgk3,Nck1,Rab10,Psat1,Mcmbp,Adap2,Ikbke,Agpat4,Cd274,Ezr,Milr1,Lcp2,Vezt,Acvr1b,Tut7,Ppp1r12b,Mfap3l,Kat2b,Nod2,Chd9,Cx3cl1,Irgm1,Rsad2,Rab21,Plekhn1,Dock4,Nfkbia,Rims3,Nat2,Sass6,Trim13,Pgap2,Kitl,Etv6,Plekhf2,Tgs1,Msr1,Ldha,Rhoc,Slamf7,Dnaja2,Pbx1,Ccne1,Rcn1,Abcc5,Socs3,Ddx58,Mppe1,Oas3,Slc30a1,Serpinb2,Itga5,Cnn3,Trim36,Spire1,Tmtc2,Rab9,Cdc42ep2,Mtfr2,Slc15a3,H2-Aa,Prdm1,S100a8,Arl5c,Plat,Mecp2,Pgs1,Rnd3,Stoml1,Ifi209,Snx10,Lacc1,Ppfia3,Rgs3,Cycs,Ociad1,Rab32,Sgcb,Lipg,Gadd45g,Map4k4,Myc,Mtcp1,Il18,Plod3,Phyh,Rnf14,Ciapin1,Ifi207,Stxbp3,Thbs1,Pdpn,Tnks1bp1,Mov10,Sema4a,Gadd45b,Il15ra,Ccnj,Map2k4,P2ry13,Crbn,Pdk3,Lpar1,Ccl2,Hsd17b7,Cd302,Mx2,Marco,Nfkbiz,Nr3c1,Maff,Gpsm2,Asap3,Asah2,Ifit3b,Rap2c,Traf2,Hdac1,F10,Kif5c,Tyk2,Slc25a12,Jmjd6,Mtmr14,Hdc,Mthfd2,Plekha5,Cd14,Trim14,Arf4,Pde4b,Xrn1,Mark2,Ifit3,Stap1,Noct,Rab11fip1,Abr,Atp2b4,Gk,Kmt5a,Chic2,Fam20c,Rgcc,Slc29a3,Gbp9,Ifi204,Acod1,Znrf1,Samsn1,Spsb1,Phlda1,Nt5c3,Ppp1r15a,Dmxl2,Dcp2,Rhou,Marf1,Grk3,Wars,Rhbdf2,Plod2,Vcpip1,Casp3,Oas2,Klf8,Klhl25,Flrt3,Cx3cr1,Fam111a,Psmb6,Ifi214,Map3k8,Ppp6r1,Mdn1 |
| 1.183e-39 | -89.63 | positive regulation of cellular protein metabolic process | biological process | GO:0032270 | 1562 | 250 | 20694 | 1406 |
Tnfrsf1b,Rnf139,Nlrp3,Scimp,Sphk1,Crkl,Stat1,Jak2,Tlr6,Nlrc4,Cycs,Inhba,Trib1,Tnfaip3,Rictor,Ripk3,Cysltr2,Tnks1bp1,Peli1,Stat3,Bcl2l11,Src,Fpr2,Hcls1,Eif4g2,Map2k1,Lif,Pdgfb,Flt1,Ptafr,Lpar1,Tnfsf15,Ccl8,Myc,Pde5a,Htr2a,Pdgfrb,Fzd5,Rnf19b,Ptk2,Ccl9,Nr1h3,Antxr1,Hspa2,S1pr2,Birc2,Spry2,Dnajb2,Csf1,Nupr1,Il15,Fcgr1,Arrdc4,Tlr9,Apaf1,Nfkbia,Adrb2,Ccl2,Birc3,Ezr,Parp14,Mecp2,Dcun1d3,Vegfc,Rbpms,Ifna2,Map3k8,Glipr2,Ccl7,Eif2ak2,Mdm2,Mlkl,Ifna1,Pdgfc,Psme1,Trib3,Polr2g,Pmaip1,Il1b,Tlr3,Ikbkg,Ppp2r5a,Tnfrsf14,Ccnd1,Psmd10,Cdk5r1,Prkce,Thbs1,Plk2,Grk3,Prnp,Fbxo4,Ctsc,Bmp2,Il6,Ccnd2,Psme2,Acvr1b,Itga5,Cflar,Mid1,Bcl6,Gdf15,Mmp25,Ednrb,Ppp1r15a,Agrn,Il12b,Txn1,Il1rn,Gadd45b,Mefv,Tmem67,Notch2,Egr1,Rgcc,Ifna6,Nck1,Rnf19a,Ift57,Acvrl1,Myd88,Serp1,Tnfsf10,Met,Cdkn1a,Casp8,Arid5a,Sdc4,Fcgr2b,Kdr,Kitl,Cx3cl1,Mdfic,Irak2,Ythdf1,Zc3h12a,Il18,Notch1,Uaca,Marco,Pim1,Tlr2,Map4k4,Casp4,Csf3,Gcnt2,Casp1,Jarid2,Ptprj,Ldlr,Nmi,Nek6,Traf2,Ifna5,Lrp4,Ripk2,Parp9,Mul1,Irgm2,Ifna4,Rnf14,Tab2,Gadd45g,Cop1,Mmp14,Stap1,Edn1,Sema4c,Nod2,Mtcp1,Nsd3,Lrp8,Fas,Hdac1,Cx3cr1,S100a8,Ppp1r15b,Plaur,Acvr1,Map2k4,Plpp3,Atp2b4,Ptger4,Hspa1a,Cenpe,Aim2,Ccl22,Sirt1,Mmp9,Lgals9,Pik3r6,Sqstm1,Htr2b,Cav1,Lyn,Tnip1,Osm,Clcf1,Rapgef2,Hsph1,Spn,Tank,Fam129a,Hspa1b,Rap2c,Atm,Cd80,Higd1a,Acsl1,Mmd,Ksr1,Ptgs2,Ankib1,Ahrr,Malt1,C3,Cd74,Gclc,Tlr1,Map3k6,Igf1r,Larp1,Cd40,Phip,Nox1,Jdp2,Kat2b,Ifnb1,Nod1,Ccl5,Icam1,Pik3r5,Angpt1,Pml,Ccr1,Rasgrp1,Ccl12,Tpx2,Syk,Ccl4,Fam162a,Jun,Fzd1,Mapkbp1,Plk3,Tnf,Il1a,Daxx,Ccl3 |
| 1.340e-39 | -89.51 | GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_DN | 153 | 73 | 15632 | 1249 |
Gbp2,Tnfaip3,Ncoa7,Csrnp1,Aim2,Prdm1,Ifih1,Isg15,Ddx58,Il1a,Stat2,Ifi44,Itgb8,Dhx58,Bcl2a1d,Rsad2,Plekhf2,Ifit2,Tnf,Klf6,Otud1,Irak2,Bcl2a1a,Cxcl1,Il1b,Il15ra,Herc6,Nr4a3,Ptgs2,Tnfsf15,Trim26,Cxcl2,Inhba,Gch1,Dusp6,Ccl5,Map4k4,Nampt,Ifit1bl2,Ppp1r15a,Ppm1k,Slamf7,Zc3hav1,Tap1,Vcpip1,Slc28a2,Egr1,Ddx60,Stard5,Peli1,Ifnb1,Bcl2a1b,Sod2,Fam43a,Ifit1bl1,Cited2,Znfx1,Socs3,Oasl1,Egr3,Fam111a,Ifit3b,Dnajb4,Tnip3,Atxn7l1,Isg20,Cd69,Tdrd7,Ccrl2,Rnf19a,Jag1,Ifit3,Il10 |
| 1.773e-39 | -89.23 | GO_REGULATION_OF_CYTOKINE_PRODUCTION | MSigDB lists | GO_REGULATION_OF_CYTOKINE_PRODUCTION | 523 | 140 | 15632 | 1249 |
Ptger4,Zc3h12a,Ptgs2,Clec5a,Ptafr,Il12b,Cmklr1,Thbs1,Igf2bp2,Pf4,Cd86,Klf2,Ube2l6,Ifi208,Nmi,Tlr1,Uba7,Nfkbil1,Malt1,H2-Q7,Pml,Il1a,Hif1a,Ddx58,Sphk1,Isg15,Socs1,Fgr,Nod1,Cd83,Tnfrsf8,Ripk3,Relb,Src,Axl,Ifi213,Casp1,Ifnar1,Birc2,Cd40,Hspa1a,Ifi205,Tnfsf4,Ebi3,Nox1,Irf1,Mefv,Tlr2,Birc3,Clec4n,Rabgef1,Irf8,Il10,P2ry2,Ifi203,Rasgrp1,Mapkapk2,Tlr6,Prnp,Nlrp3,Il4ra,Zbp1,Tnfrsf14,Angpt1,H2-Q4,Nlrc5,Ezr,Ccl12,Irf4,Peli1,Il6,Nod2,Tlr3,Hmox1,Ripk2,Adora2b,Il18,Nr4a3,Nfkb2,Ikbke,Htr2b,Il1b,H2-Eb1,Pde4b,Fzd5,Cd274,Serpine1,Irf7,Inhba,Il12rb1,Aim2,F11r,Cd74,Ifih1,Rnf135,Myd88,Cd14,Ccdc88b,Irak3,Tnfaip3,Tnf,Traf2,H2-Q6,Ifi209,Bcl6,Ankrd17,Errfi1,Dhx58,Rsad2,Tlr9,C3,Ifi204,Lyn,Jak2,Tax1bp1,Nfkb1,Rel,Mndal,Nos2,Trim21,Ifi211,Zfp36,Trim56,Ddx60,Mul1,Cx3cl1,Ifi214,Il15,Il27,Cd34,Cd80,Clec4e,Tspo,Ifi207,Zc3hav1,Spn,Gsdmd,Eif2ak2,Syk,Ifnb1 |
| 2.058e-39 | -89.08 | GSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_DN | 194 | 82 | 15632 | 1249 |
Csrnp1,Atp11a,F11r,Usp18,Sphk1,Isg15,Ube2f,1600014C10Rik,Ifit1,Gbp2,Stat5a,Cst7,Gypc,Insl6,Traf2,Birc2,Stat3,Cish,Gbp4,Gbp9,Ly75,Glipr2,Bcl2a1d,Ptger4,Pcgf5,Oas1g,Cxcl10,Gpr85,Bcl2a1a,Il1rn,Clic4,Ifit1bl2,Cdyl,Gja1,Ccl5,Lad1,Tap2,Irf7,Car13,Mmp13,Wars,Oas2,Parp12,Palld,Ccnd2,Etv3,Sdc1,Nxf1,Papss2,Sdc4,Rras2,Tspo,Gpc1,Foxp4,Slfn5,Gadd45b,Spsb1,Nfkbia,Ifit1bl1,Flrt3,Bcl2a1b,Sod2,Dusp2,Il4i1,Mllt6,Dram1,Cd200,Socs3,Oasl1,Aida,Fscn1,Kdr,Cdkn1a,Abtb2,Jdp2,Rel,Cep350,Cnn3,Htra1,Psme2,Oas1a,Cd69 |
| 2.308e-39 | -88.96 | GO_CELLULAR_RESPONSE_TO_CYTOKINE_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_CYTOKINE_STIMULUS | 557 | 145 | 15632 | 1249 |
Osm,Irf7,Flrt2,Ccl5,H2-Eb1,Ccr1,Cxcl2,Il12rb1,H2-Aa,Trim26,Il2rg,Psmb6,Tlr3,Il1b,Keap1,Irak2,Vcam1,Cxcl1,Csf3r,Oas3,Traf2,H2-Q6,Stat5a,Tnf,Ifit2,Rsad2,Gbp9,Stat3,Psmb10,Cd74,Aim2,Irak3,Ifna2,Ccl3,Nos2,Pid1,Tnfrsf1b,Nfkb1,Xaf1,Il18rap,Psme2,Trim21,Isg20,Csf1,Ifit3b,Oasl1,Nfil3,Ccl4,Jak2,Ass1,Mid1,Ifnb1,Ifna5,Cx3cl1,Fas,Cd86,Klf2,Ifit1bl2,Tyk2,Oas2,Csf3,Ifna6,Tnfsf15,Ptafr,Cxcl10,Il12b,Oas1g,Zc3h12a,Ptger4,H2-Ab1,Pf4,Il15ra,Cmklr1,Birc2,Cd40,Psmb9,Ifnar1,Axl,Psma6,Pde1b,Gbp4,Cish,Isg15,St3gal6,Socs1,Trim12c,Stat2,Hif1a,Il1a,Icam1,Pml,Itga4,Irf2,H2-Q7,Psme1,Gbp2,Hck,Daxx,Tnfrsf8,P2ry2,Tnfsf14,Irf8,Ifit3,Birc3,Psmb8,Sirt1,Ccrl2,Oas1a,Acsl1,Irf1,Socs3,Stat1,Il13ra1,Tnfsf4,Ifi35,Ebi3,Xcr1,Socs7,Hcls1,Clcf1,Psmd10,Flrt3,Ccl12,H2-Q4,Cx3cr1,Ifit1bl1,Nfkbia,Il18bp,Ccl2,Il6,Ccr3,Irf4,Edn1,Il4ra,Etv3,Ccl22,Egr1,Lrp8,Samhd1,Tnfrsf14,Pnpt1,Adar,Fcgr1,Ifna1,Ciita |
| 2.413e-39 | -88.92 | regulation of cell death | biological process | GO:0010941 | 1686 | 262 | 20694 | 1406 |
Glrx,Ddit4,Birc3,Apaf1,Adrb2,Pf4,Slc9a1,Eif2ak2,Pdpn,Stat5a,Socs3,Plekhn1,Rnf34,Eef1e1,Dcun1d3,Ppp2r1b,Mecp2,Kmo,Ptk2,Ptpn2,Pdgfrb,Plagl2,Pde5a,Myc,Hcar2,Nupr1,Csf1,Col18a1,Spry2,Birc2,Map2k1,Hcls1,Bcl2a1a,Src,Phlda1,Stat3,Bcl2l11,Hck,Egr3,Peli1,Nr3c1,Tnfsf15,Lpar1,Arg2,Cxcl10,Klrk1,Nlrp3,Hk3,Tnfrsf1b,Plac8,Optn,Cysltr2,Ripk3,Traf5,Cd200,Adar,Tnfaip3,Cycs,Inhba,Nlrc4,Tlr6,Jak2,Prdx5,Stat1,Timp1,Sphk1,Fcgr2b,Abcc1,Pla2g4a,Casp8,Cdkn1a,Tnfsf10,Met,Ift57,Nck1,Cx3cl1,Rffl,Kitl,Bcl2a1b,Kdr,Dusp6,Cacybp,Gadd45b,Il1rn,Txn1,Agrn,Il12b,Ednrb,Gdf15,Bcl6,Bnip3,Rgcc,Egr1,Notch2,Bmp2,Ctsc,Casp2,Rel,Prnp,Cd34,Plk2,Cpeb4,Mt1,Thbs1,Lox,Tnfrsf8,Cflar,Dusp1,Itga5,Hif1a,Ccnd2,Kdm4a,Il6,Pim3,Il1b,Pmaip1,Mdm2,Btg2,Prkce,Cdk5r1,Psmd10,Nr4a3,Tnfsf14,Nfkb1,4930453N24Rik,Ikbkg,Casp3,Gja1,Itgav,Map2k4,Tnfsf4,Plaur,Acvr1,Nr4a1,Il10,S100a8,Cx3cr1,Irf1,Phlpp1,Hdac1,Adora2a,Egln3,Tspo,Usp42,Abcb1a,Sav1,Sgk3,Zfp36,Gadd45g,Itga4,Irak3,Gclm,Fas,Lrp8,Nfkbid,Nod2,Serpine1,Serpinb2,Edn1,Dnaja1,Sp110,Casp1,Csf3,Clec5a,Asns,Casp4,Map4k4,Stk40,Mul1,Ripk2,Rilpl1,Traf2,Notch1,Chmp4b,Trip10,Prokr1,Il18,Zc3h12a,Irak2,Hmox1,Pim1,Uaca,Pim2,Asah2,Eya4,Ccl12,Rras2,Ciapin1,Pml,Atf3,Angpt1,Bfar,Ccl3,Daxx,Tnf,Plk3,Nsmaf,Fzd1,Jun,Sod2,Fam162a,Stxbp1,Cited2,Syk,Gclc,Cd74,Malt1,Nqo1,Insl6,Rnf31,Hk1,Icam1,Serpinb9,Ccl5,Cdkn2d,Ifnb1,Nod1,Irs2,Phip,Nox1,Cd40,Igf1r,Mtdh,Hspa1b,Plscr1,Hsph1,Rapgef2,Fam72a,Cd38,Pik3cd,Tax1bp1,Ptgs2,Traf1,Bcl2a1d,Fos,Ifit2,Higd1a,Nes,Atm,Cd274,Acsl5,Axl,Hp,Trim13,Txnrd1,Grina,Sirt1,Mmp9,Ier3,Arf4,Arel1,Clcf1,Ahr,Osm,Ncoa7,Slc7a11,Sell,Lyn,Cav1,Chst11,Htr2b,Itpr1 |
| 4.030e-39 | -88.41 | MODULE_84 | MSigDB lists | MODULE_84 | 507 | 137 | 15632 | 1249 |
Hk3,Ifi207,Dnase1l3,Olr1,Sdc1,Fpr2,Ifi214,Vcan,Fcgr2b,Ctsc,Parp14,Aoah,Spsb1,Plac8,Bcl2a1b,Cdkn1a,Adam19,Ccl4,Ifi204,Lyn,Pim2,Mmp9,Ifi211,Isg20,Slpi,Ppp4r2,Cav1,Lap3,Lmo4,Mndal,S100a8,Tnfrsf1b,Ikbkg,Tnfaip3,Sla,Cd14,Cd74,Nupr1,Fgl2,Ifi44,H2-Q6,Mtus1,Bcl6,Csf3r,Cd302,Ifi209,Tnf,Slc16a3,Il1b,Vcam1,Il2rg,Parp12,Ddit4,H2-Aa,Lcp2,Serpine1,Plek,Ccr1,H2-Eb1,Pde4b,Dusp6,Psd4,Ccl5,Tap1,Pfkfb3,Plau,Ccnd2,Il4ra,Ikzf1,Igsf6,Il6,Zyx,H2-Q4,Cx3cr1,Ifit1bl1,Ccl12,Tagln,Slc7a11,Rgs1,Tnfaip2,Hcls1,Irf1,Tlr2,Sema4a,Ier3,Acsl1,Ifi35,Stat1,Stat4,Pla2g7,Ifi203,Cd69,Plscr1,St3gal5,Marco,Irf8,Itgal,Gna15,Birc3,Crim1,Gbp2,Hck,Icam1,Fgr,Sell,Isg15,H2-Q7,Rhoh,Lif,Ccnd1,Bcl2a1d,Itpr1,Ifi205,Ifi213,Casp1,Cst7,Glrx,Bcl2a1a,Il1rn,Tnfsf10,Slamf8,Tgfbi,Fpr1,H2-Ab1,Dgka,Stx11,Ube2l6,Tlr1,Ifi208,Samsn1,Cd86,Nampt,Junb,Rgl1,Ifit1bl2,Slc7a8,Gch1 |
| 4.944e-39 | -88.20 | response to bacterium | biological process | GO:0009617 | 725 | 155 | 20694 | 1406 |
Peli1,Hck,Nfkbil1,Gbp3,Tnfsf8,Cmpk2,Fpr2,Lcn2,Casp1,Tmem229b,Cxcl10,Ptafr,Klrk1,Cxcl9,Serpina3f,Tab2,Nos2,Slfn4,Ripk2,Irgm2,Tnfrsf1b,Zc3h12a,Il18,Ifi211,Irak2,Optn,Plac8,Slfn2,Ifi44,Mndal,Nlrp3,Gfi1,Rgs1,Tlr6,Jak2,Stat1,Nlrc4,Nfkbib,Clec4e,Tlr2,Clec4d,Trib1,Tnfaip3,Cxcl3,Ccl2,Gbp2,Slamf8,Fcgr1,Psmb9,Pf4,Nfkbia,Tlr9,Ifit3,Tnfsf4,Cx3cr1,Il10,Gbp7,Iigp1,Ptger4,Herc6,Eif2ak2,Cxcl1,Fzd5,Fcgr4,Zfp36,Tent5a,Irak3,Ptgir,Nr1h3,Stap1,Resf1,Sp110,Tgtp1,Tap2,Serpine1,Nod2,Plscr1,Trem1,Spn,Bmp2,Cd86,Adgrl2,Ifit1,Gbp2b,Il6,Cd80,Slpi,Saa3,Ptgs2,Cflar,Abr,Ifna1,Acp5,Dhx58,Il1b,Isg15,Cd274,Hp,Lgals9,Mapkapk2,Axl,Irf8,Acod1,Itgav,Ifnar1,Usp18,Ifi205,Trim30a,Cxcl11,Prkce,Cav1,Lyn,Tnfrsf14,Nfkb1,Irgm1,Noct,Myd88,Ly6a,Ccl12,Arid5a,Gch1,AA467197,Fcgr2b,Plaat3,Gbp9,Nlrc5,Syk,Tnf,Mt2,Ifi204,Jun,Malt1,Gsdmd,Ednrb,Cd14,Junb,Bnip3,Pde4b,Oas2,Il1rn,Il12b,Tlr1,Cd180,C3,Gbp8,Ankrd17,Fgr,Mtdh,Serpinb9,Cxcl2,Ccl5,Tnip3,Notch2,Ifnb1,Nod1 |
| 5.258e-39 | -88.14 | SEKI_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | SEKI_INFLAMMATORY_RESPONSE_LPS_UP | 68 | 49 | 15632 | 1249 |
Nfkb2,Vcam1,Cxcl1,Zc3h12a,Ripk2,Cxcl10,Icosl,Stx11,Maff,Cxcl2,Gch1,Slc4a7,Plk2,Bmp2,Tnfaip3,Gbp2,Lif,Gbp3,Rnd1,Icam1,Egr2,Slc15a3,Rsad2,Gpr68,Sele,Nfkbie,Birc2,Zmynd15,Cd40,Tnip1,Tnfaip2,Egr3,Ier3,Tlr2,Rab20,Plscr1,Csf1,Ccrl2,Jdp2,Birc3,Casp4,Rel,Egr1,Fas,Nfkbiz,Sod2,Ccl12,Gadd45b,Nfkbia |
| 5.980e-39 | -88.01 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN | 160 | 74 | 15632 | 1249 |
Rtp4,Fas,Ddx60,Slfn5,Tap1,Pnpt1,Cd80,Zbp1,Il15,D16Ertd472e,Znfx1,Nlrc5,Fam43a,Samd9l,Il6,Peli1,Parp14,Kcnj2,Lyn,Ifit3b,Irf1,Dnajb4,Dusp16,Col27a1,Zc3h12c,Ifit3,Abtb2,Il18rap,Xaf1,Dcp1a,Plscr1,Ifih1,Dtx3l,Isg15,Gbp3,Trim12c,Stat2,Ddx58,Il1a,Csrnp1,Prrg4,Aim2,Ncoa7,Cd38,Oas3,Traf2,Otud1,Homer1,Sp140,Tnf,Ifit2,Dhx58,Tlk2,Ifi44,Stat3,Map3k8,4930453N24Rik,Dusp5,Pcgf5,Herc6,Cmpk2,Epsti1,Gtpbp2,Irf7,Lad1,Cd274,Pde4b,Nampt,Slc31a2,Wars,Tnfsf15,Arl5b,Trim26,Ext1 |
| 5.980e-39 | -88.01 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_DN | 160 | 74 | 15632 | 1249 |
Cd38,Stat2,Ddx58,Isg15,Traf1,Gbp3,Mxd1,Marcksl1,Csrnp1,Dhx58,Ifi44,Batf2,Arid5a,Otud1,Oas3,Tnf,Lipe,Phf11b,Ifit2,Sp140,Epsti1,Il15ra,Zhx2,Cmpk2,Gtpbp2,Irak2,Ptgs2,Herc6,Kdm6b,Dusp5,Ripk2,Wars,Oas2,Ext1,Arl5b,Tnfsf15,Ppm1k,Irf7,Ifit1bl2,Pde4b,Gch1,Slfn5,Phf11c,Zbtb5,Pfkfb3,Pnpt1,Adar,Phf11a,Slamf7,Rtp4,Fas,Ddx60,Parp14,Peli1,D16Ertd472e,Ifit1bl1,Nlrc5,Hivep2,Sod2,Dusp16,Col27a1,Phf11d,Irf1,Ifit3b,Ebi3,Oasl1,Rictor,Il18rap,Xaf1,Plscr1,Zc3h12c,Irf8,Ifit3,Abtb2 |
| 1.239e-38 | -87.28 | GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN | 157 | 73 | 15632 | 1249 |
Itpr1,P2ry13,Oas3,Dync1h1,Lipe,Parp8,Ogfrl1,Cdyl2,Hdac1,Mlkl,Minpp1,Rab21,Dbnl,Tnfsf8,Rnf135,Sertad3,Itga4,Aim2,Apba1,Rab3ip,Gnb4,Rnf34,Cutc,Asah2,Sipa1l1,Golga3,Ttc9c,Rgl1,Sesn3,Ccl5,G3bp2,Wars,Il12rb1,Hap1,Ube2l6,Ext1,Il18,Nsmaf,Tlr3,Xkr8,Parp3,Slc37a3,Keap1,Gtpbp2,Gca,Phactr4,Tor1aip2,Kat2b,Arl4a,Rars,Stxbp1,Tnfrsf14,Angpt1,Sgcb,Cenpj,Nos2,Casp8,Plekha2,Clic5,Psmb8,Atm,Pdk3,Il18rap,Rasgrp1,Casp2,Akt3,Cysltr2,Zeb1,Aida,Lyn,Asb13,Uaca,Armc8 |
| 1.584e-38 | -87.04 | GSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_DN | MSigDB lists | GSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_DN | 189 | 80 | 15632 | 1249 |
Abtb2,Ifit3,Ogfr,Mndal,Ifi211,Trim21,Isg20,Zfp36,Plscr1,St3gal5,Oas1a,Ifi203,Cd69,Tdrd7,Xaf1,Ifi35,Casp7,Oasl1,Ifi204,Ifit3b,Lyn,Rbms1,H3f3b,Hivep2,Ifit1bl1,Ets2,Dnaja1,4932438A13Rik,Rin2,Fas,Nxf1,Ifi214,P2ry14,Slc30a1,Arl4a,Adar,Ifi207,Zc3hav1,Tap1,4930523C07Rik,Ifit1bl2,Rgl1,Gch1,Irf7,Trim26,Nmi,Ifi208,Wars,Rapgef2,Oas2,Uba7,Rnf19b,Dusp5,Oas1g,Cxcl10,Cmklr1,Gca,Cldnd1,Il15ra,Tfec,Sp110,Trafd1,Ppp2r2a,Ifit2,Ifi213,Klf6,N4bp1,Arid5a,Ifi205,Ifi209,Birc2,Ifi44,Tlk2,Rsad2,Malt1,Ier2,Pml,Socs1,Isg15,Mvp |
| 1.979e-38 | -86.82 | positive regulation of macromolecule metabolic process | biological process | GO:0010604 | 3280 | 408 | 20694 | 1406 |
Aim2,Mov10,Ptger4,Atp2b4,Ets2,S100a8,Acvr1,Plaur,Hinfp,Nr4a1,Tnfsf4,Hdac1,Adam19,Serpine1,Nod2,Lrp8,Stap1,Cop1,Itgb8,Hivep3,Gadd45g,Zfp36,Parp9,Ifna4,Irgm2,Tab2,Nmi,Ptprj,Tnfsf8,Map4k4,Dyrk2,Icosl,Gcnt2,Csf3,Pim1,Tlr2,Uaca,Pid1,Notch1,Irak2,Tiparp,Fzd1,Ccl3,Stat4,Syk,Ccl4,Ccr1,Pml,Eya4,Ago3,Pim2,Pik3r5,Prdm1,Noct,Ifnb1,Nod1,Jdp2,Serpinb9,Ccl5,Map3k6,Psip1,Igf1r,Larp1,Phip,Wars,Nox1,Cd74,C3,Tlr1,Malt1,Junb,Fos,Ankib1,Ahrr,Atm,Tent4a,Cd80,Higd1a,Acsl1,Cd38,Timeless,Hspa1b,Tank,Fam129a,Lyn,Ncoa7,Tnip1,Ahr,Clcf1,Helz2,Ptch1,Lmo4,Htr2b,Irf8,Pik3r6,Hhex,Arf4,Ier3,Glipr2,Ell2,Ccl7,Mecp2,Vegfc,Dcun1d3,Cenpj,Maml2,Ezr,Parp14,Scyl2,Fcgr1,Slc9a1,Apaf1,Pf4,Tlr9,Spic,Spry2,Aff1,Klf2,Csrnp1,Birc2,Rnf19b,Ccl9,Zeb1,Myc,Pde5a,Htr2a,Plagl2,Dcp1a,Lpar1,Pdgfb,Mafg,Ptafr,Lcn2,Tfec,Hcls1,Tnks1bp1,Egr3,Src,Stat3,Trib1,Cycs,Adar,Maff,Cysltr2,Ripk3,Crkl,Stat1,Nlrc4,Optn,Pou2f2,Kitl,Cx3cl1,Mdfic,Nlrc5,Egr2,Kdr,Arid5a,Fcgr2b,Zfp281,Ift57,Met,Serp1,Myd88,Notch2,Egr1,Rgcc,Kdm6b,Txn1,Il1rn,Gadd45b,Bcl6,Mmp25,Gdf15,Ppp1r15a,Ciita,Cflar,Jag1,Il6,Kdm4a,Psme2,Ccnd2,Itga5,Hif1a,Rel,Ctsc,Plk2,Thbs1,Prdm9,Grk3,Prnp,Fbxo4,Crlf3,Relb,Ccnd1,Psmd10,Nr4a3,Casp3,Gja1,Ikbkg,Mapkapk2,Fubp1,Ppp2r3a,Hmga2,Mdm2,Pdgfc,Psme1,Plpp3,Cenpe,Hspa1a,Cx3cr1,Il10,Irf2,Ppp1r15b,Map2k4,Irf1,Mtcp1,Hmga1,Nsd3,Fas,Edn1,Sema4c,Resf1,Mmp14,Med13,Dtx3l,Irf4,Mul1,Ripk2,Lrp4,Rnf14,Nek6,Traf2,Ifna5,Jarid2,Casp1,Ldlr,Casp4,Hivep2,Marco,Gfi1,Sele,Ythdf1,Zc3h12a,Il18,Tcf4,Jun,Pcgf5,Fam162a,Mapkbp1,Plk3,Tnf,Daxx,Il1a,Tpx2,Cited2,Bambi,Atf3,Ccl12,Rasgrp1,Sertad3,Taf4b,Il27,Ikzf1,Angpt1,Kat2b,Irs2,Jmjd6,Icam1,Mycl,Mtdh,Cd40,Dr1,Parp3,Pou3f1,Gclc,Max,Arid5b,Mmd,Bcl9,Ier2,Ksr1,Ptgs2,Nfil3,Klf6,Casz1,Rap2c,Hsph1,Rapgef2,Pik3cd,Spn,Plscr1,Cav1,Klf7,Osm,Pbx1,Trim30a,Spire1,Sqstm1,Lgals9,Ccl22,Arel1,Mmp9,Sirt1,Map3k8,Stat5a,Eif2ak2,Plagl1,Pnpt1,Plekhn1,Rbpms,Arid4a,Ifna2,Tnc,Birc3,Mllt6,Med21,Adrb2,Arrdc4,Nfkbia,Batf,Ccl2,Gsap,Dnajb2,Nupr1,Csf1,Il15,Spen,Antxr1,Hspa2,Ifrd1,S1pr2,Rhoq,Ptk2,Etv6,Fosb,Kdm5b,Nr1h3,Ccl8,Fzd5,Cebpd,Pdgfrb,Tnfsf15,Wdr43,Lif,Flt1,Fpr2,Stat2,Eif4g2,Map2k1,Nr3c1,Peli1,Bcl2l11,Tnfaip3,Irf7,Inhba,Rictor,Ddx58,Hmgn3,Sphk1,Tcea1,Tlr6,Jak2,Zc3hav1,Nlrp3,Scimp,Plac8,Tnfrsf1b,Rnf139,Cacybp,Cdkn1a,Nampt,Casp8,Etv5,Sdc4,Nck1,Ifna6,Rnf19a,Acvrl1,Tnfsf10,Tmem67,Agrn,Il12b,Mefv,Ednrb,Tra2a,Il2rg,Cnn2,Tnfrsf8,Mid1,Nfkb2,Acvr1b,Bmp2,Lhx2,Tnfrsf14,Ppp2r5a,Nfkb1,Prkce,Cdk5r1,Tlr3,Ifnar1,Trib3,Pmaip1,Polr2g,Tet2,Il1b,Mlkl,Btg2,Ifna1 |
| 2.477e-38 | -86.59 | GO_REGULATION_OF_INNATE_IMMUNE_RESPONSE | MSigDB lists | GO_REGULATION_OF_INNATE_IMMUNE_RESPONSE | 348 | 110 | 15632 | 1249 |
Jak2,Tlr9,Lyn,Tnip3,Ifi204,Psme2,Ifi211,Nfkb1,Ikbkg,Casp8,Mndal,Cav1,Clec4e,Zc3hav1,Ifi207,Ddx60,Nr1h3,Mul1,Ifi214,Ifna5,Ifnb1,Parp9,Syk,Ptpn2,Nlrc4,Ikbke,Irak2,Ripk2,Psmb6,Tlr3,Wdfy1,Ccl5,Irf7,Cd14,Myd88,Tnfaip3,Ifna2,Irak3,Aim2,Psmb10,Ifih1,Rnf135,Tab2,Usp18,Dhx58,Rsad2,Ankrd17,Ifi209,H2-Q6,Tnip1,Gfi1,Socs3,Stat1,Tlr2,Irf1,Plscr1,Rasgrp1,Ifi203,Smpdl3b,Psmb8,Clec4n,Birc3,Marco,Adar,Ifna1,Tap1,Samhd1,Mapkapk2,Tlr6,Prkce,Peli1,Irf4,Nod2,Nfkbia,Nlrc5,H2-Q4,Psmd10,Trafd1,Il12b,Clec4d,Serpinb9,Tlr1,Nmi,Ifna6,Ifi208,Tyk2,Pik3r6,Cd86,Nod1,Hck,Relb,Malt1,H2-Q7,Psme1,Nfkbil1,Socs1,Fgr,Trim12c,Ddx58,Cd180,Stat2,Psma6,Ifnar1,Ifi213,Src,Ifi205,Hspa1a,Tank,Birc2,Psmb9 |
| 3.446e-38 | -86.26 | GO_REGULATION_OF_DEFENSE_RESPONSE | MSigDB lists | GO_REGULATION_OF_DEFENSE_RESPONSE | 708 | 165 | 15632 | 1249 |
Tlr9,C3,Ifi204,Tnip3,Lyn,Jak2,Ccl4,S100a8,Ikbkg,Nfkb1,Tnfrsf1b,Ednrb,Cav1,Nos2,Mndal,Casp8,Ifi211,Psme2,Rictor,Ddx60,Nr1h3,Mul1,Cx3cl1,Ifi214,Il15,Il27,Clec4e,Ifi207,Zc3hav1,Spn,Eif2ak2,Syk,Nlrc4,Ptpn2,Pla2g4a,Parp9,Ifna5,Ifnb1,Tlr3,Psmb6,Ripk2,Adora2b,Il18,Irak2,Ikbke,Il1b,Fcgr4,Gja1,Ccl5,Serpine1,Irf7,Osm,Wdfy1,Il12rb1,Aim2,Usp18,Tab2,Rnf135,Psmb10,Ifih1,Myd88,Cd14,Irak3,Ifna2,Tnfaip3,Ccl3,Tnf,H2-Q6,Ifi209,Bcl6,Ankrd17,Sele,Dhx58,Rsad2,Tnfsf4,Socs3,Stat1,Itpkc,Irf1,Mefv,Adrb2,Tlr2,Tnip1,Trem1,Gfi1,Clec4n,Birc3,Rabgef1,Psmb8,Marco,Il10,Casp4,Plscr1,Htra1,Pla2g7,Smpdl3b,Rasgrp1,Leng9,Ifi203,Abr,Tlr6,Mapkapk2,Nlrp3,Ifna1,Adar,Samhd1,Tap1,Nlrc5,Ifit1bl1,Cx3cr1,H2-Q4,Nfkbia,Ccl12,Psmd10,Zyx,Irf4,Peli1,Il6,Ccl2,Prkce,Nod2,Cd55,Ptger4,Traf3ip2,Zc3h12a,Ptgs2,Serpinb9,Clec4d,Il12b,Elmod2,Trafd1,Ifit1bl2,Cd86,Slc7a2,Pik3r6,Ifi208,Ifna6,Nmi,Tlr1,Tyk2,Nfkbil1,H2-Q7,Psme1,Malt1,Pml,Calcrl,Stat2,Cd180,Ddx58,Trim12c,Fgr,Socs1,Nod1,Relb,Hck,Src,Ifi213,Casp1,Ifnar1,Psmb9,Birc2,Ifi205,Hspa1a,Tank,Psma6 |
| 4.696e-38 | -85.95 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_UP | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_UP | 182 | 78 | 15632 | 1249 |
Icam1,Hif1a,Il1a,Atp11a,Upp1,Gbp3,Sphk1,Gbp2,Cd83,Sav1,Timp1,Cd40,Tnf,Errfi1,Oaf,Batf2,Cp,Rffl,Ccdc86,Ifi44,Lox,Serpinb9,Ttc39b,Zc3h12a,Il15ra,Cxcl1,Il1rn,Plk2,Slc7a2,Serpine1,Pde4b,Mmp13,Car13,Csf3,Cxcl2,Maff,Inpp5b,Plagl1,Cyth3,Cx3cl1,Rars,Atf3,Rnd3,Rbms2,Gadd45b,Spsb1,Map3k6,Sod2,Sbds,Itgav,Ifrd1,Gadd45g,Edn1,Ccl2,Il6,Trib1,Odc1,Kpna3,Cd200,Itga5,Dusp16,Cdkn1a,Pmepa1,Nfil3,Znrf1,Dr1,Tnfaip2,Rgs1,Ccl4,Tax1bp1,Tnip1,Il10,Zc3h12c,Ubr4,Jdp2,Slc39a14,Procr,Akt3 |
| 1.011e-37 | -85.18 | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP | 193 | 80 | 15632 | 1249 |
Pml,Trim12c,Isg15,Ifih1,Ddx58,Usp18,Myd88,Cd164,Casp1,N4bp1,Ifi213,Ifit2,Phf11b,Oas3,Ifi205,Ifi209,Psmb9,Rab9,Slc15a3,Ifi44,Nr3c1,Dhx58,Rsad2,Oas1g,Herc6,Tnfsf10,Gtpbp2,Sp110,Ppp2r2a,Gch1,Ifit1bl2,Irf7,Cnp,Plekha4,Nmi,Ifi208,Ddit4,Ube2l6,Trim26,Oas2,Parp12,Uba7,Hk2,Usp25,Ddx60,Rtp4,Ifi214,Plagl1,Kat2b,Adar,Phf11a,Phf11c,Samhd1,Ifi207,Rapgef5,Eif2ak2,Ifit1bl1,B4galt4,Spry2,Rin2,Oasl1,Ifi35,Ifit3b,Ifi204,Phf11d,Zcchc2,Lnpep,Psmb8,Ogfr,Mndal,Ifit3,Cav1,Plscr1,Ifi211,Trim14,Isg20,Tdrd7,Ifi203,Xaf1,Oas1a |
| 1.029e-37 | -85.17 | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN | MSigDB lists | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN | 80 | 52 | 15632 | 1249 |
Pdgfb,Pdlim7,Phlda1,Csf3,Junb,Ccl5,Slfn4,Cxcl1,Bcl2a1a,Pcdh7,Slfn3,Il1rn,Nfkb2,Ikbke,Plaur,Glrx,Il1b,Pim1,Adora2b,Ptgs2,Cdc42ep4,Egr2,Errfi1,Stk40,Bcl2a1d,Tapbp,Dusp1,Tnf,Ehd1,Phldb1,Cd83,Cd14,Tnfaip3,Marcksl1,Icam1,Traf1,Il18rap,Nfkb1,Tnfaip2,Tnip1,Ccl4,Itga5,Socs3,Odc1,Ier3,Dusp2,Nfkbia,Gadd45b,Sqstm1,Bcl2l11,Bcl2a1b,Ets2 |
| 1.650e-37 | -84.69 | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDC_DN | 180 | 77 | 15632 | 1249 |
Hmox1,Smc5,Ptprj,Atp10a,Osgin2,Grina,Slfn9,Mitd1,Glrx,Ccl5,Brwd3,Jarid2,Igsf8,Samsn1,Rilpl1,Hk2,Tbc1d13,Lif,Gbp3,F11r,1600014C10Rik,Cd14,Traf5,Cd83,Rnf34,Crlf3,Ddhd1,Plekhf2,Ifit2,Csf3r,Hspa1a,Ttc39c,Klhl25,Psmb9,Tbc1d1,Oaf,Gsr,Hdac1,Fgl2,Denr,Dtx2,Mafg,Mthfd2,Asf1a,Arf4,Jak2,Clcf1,Wdr43,Frmd6,Esd,Nfkb1,Ppp1r15b,Birc3,Adap2,Cep350,Atxn7l1,Srxn1,Procr,Pou2f2,Hat1,Syne2,Tdrd7,Rnf19a,Mapkapk2,Lrp8,Abr,Sgcb,Rnd3,Nfkbia,Map3k6,Znfx1,Ppp2r5a,Igsf6,Slfn8,Fcgr2b,Mid1,Dtnb |
| 1.946e-37 | -84.53 | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP | MSigDB lists | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP | 185 | 78 | 15632 | 1249 |
Slfn4,Lcp2,Irf7,Snx10,Nampt,Inhba,Cxcl2,Inpp5b,H2-Aa,Trib3,Serpinb9,Fpr1,Cxcl10,Rnf19b,Ldha,Pkp4,Slfn3,Clic4,Rgs14,Homer1,Axl,N4bp1,Abcc5,Nfkbie,Kdm5b,Rsad2,Stat3,Ly75,Cd74,Usp18,Icam1,Zfp281,Hif1a,Ifih1,Isg15,Arg2,Agtrap,Gbp3,Ch25h,Nupr1,Ifit1,Daxx,Notch1,Cd38,Myo10,Zc3h12c,Ifit3,Irf8,Gbp7,Lmo4,Cep350,Psmb8,S100a8,Casp2,Trim21,Acsl1,Ifit3b,Sema4a,Dck,Ppa1,C3,Cflar,Spic,Znfx1,Aoah,Sod2,Ikzf1,Irgm2,Kat2b,Fpr2,Stxbp1,Aff1,Ahr,Tap1,Prdx1,Gpc1,Clec4e,Tspo |
| 1.946e-37 | -84.53 | GSE17721_LPS_VS_CPG_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_4H_BMDC_UP | 185 | 78 | 15632 | 1249 |
Sec24b,Sp110,Gcnt2,Rsbn1,Plcl2,Ptgs2,Pim1,Fndc3a,Larp1,Tlr3,Parp12,Snx2,Stxbp3,Caml,Sap30,Atp6v1d,Asah2,Jarid2,Mdfic,Apaf1,1600014C10Rik,Ube2f,Sav1,Bfar,Myd88,Gbp3,Calcrl,Zfp281,Icam1,Mxd1,Ythdf1,Tlk2,Rffl,Rab9,1110038F14Rik,D1Ertd622e,Nr3c1,Plekha5,Gypc,Pmepa1,Dusp16,Tmem219,Ccl4,Tax1bp1,Clcf1,Acsl1,Irf1,Lpar1,Etnk1,Kpna3,Ccrl2,Plscr1,Slpi,Ptch1,Rel,Psat1,Pdk3,Tnks1bp1,Rbl1,Spred1,Aff1,Gng11,Pnpt1,Sgcb,Il15,Hinfp,Aldh1b1,Ccnd2,Parp9,Tra2a,Katna1,Dusp2,Tor1aip2,Dnaja1,Ptpn2,Psip1,Sbds,Crbn |
| 3.503e-37 | -83.94 | positive regulation of response to external stimulus | biological process | GO:0032103 | 452 | 116 | 20694 | 1406 |
Irgm2,Lpar1,Parp9,Ripk2,Ifi208,Tifa,Wdfy1,Ikbke,Pdgfb,Klrk1,Raet1e,Cxcl10,Fpr2,Ifi203,Pvr,Il18rap,Trim12c,Ldlr,Ptprj,Treml4,Peli1,Tarm1,Irf7,Tlr2,Clec4e,Ddx58,Zbp1,Nlrc4,Tlr6,Jak2,Zc3hav1,Mndal,Scarf1,Ifi211,Irak2,Optn,Cd300lf,Swap70,Stat5a,Cxcl1,Aim2,Ptger4,Vegfc,Cmklr1,H60b,S100a8,Tnfsf4,Nfkbia,Tlr9,Fcgr1,Ccl2,Pla2g7,Nod2,Serpine1,Nupr1,Csf1,Ifih1,Edn1,Stap1,Ddx60,Nectin2,Nr1h3,Irak3,Pde5a,Pdgfrb,Ptgs2,Il6,Adora2b,Cd86,Ctsc,Thbs1,Plscr1,Osm,Tnip1,Cav1,Sell,Prkce,Ifi209,Tnfsf14,Tlr3,Nfkbiz,Ifi205,Acod1,Mapkapk2,Lgals9,Dhx58,Il1b,Rsad2,P2ry12,Ccl3,Ifi204,Tnf,Cx3cl1,Nlrc5,Kdr,Ccl4,Ccr1,Rasgrp1,Pla2g4a,Met,Myd88,Irgm1,Nod1,Tnip3,Ccl5,Igf1r,Ankrd17,Cxcl14,Cd74,Cd180,C3,Tlr1,Cgas,Il12b,Ifi214,Cd14 |
| 3.831e-37 | -83.85 | GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_DN | MSigDB lists | GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_DN | 168 | 74 | 15632 | 1249 |
Sp110,Il15ra,Epsti1,Tnfsf10,Irak2,Vcam1,Cxcl10,Parp3,Rnf19b,Dgka,Parp12,Stx11,Slc2a6,Scn1b,Notch1,Gnb4,Nod1,Socs1,Psmb10,Isg15,Icam1,Upp1,Usp18,Mxd1,Aim2,Prdm1,Mlkl,Tapbp,Batf2,Ifi44,Gbp9,Gbp4,Ly75,Stat3,Oas3,Psmb9,Cst7,Ppp6r1,Casp1,Ifit2,Phf11b,Tlr2,Ifit3b,Asb13,Phf11d,Parp11,Irf1,Ell2,Cd69,Xaf1,Ccrl2,Csf1,Cysltr2,Trim14,Casp4,Lmo4,Itgal,Ifit3,Psmb8,Phf11c,Slc28a2,Atp2b4,Tnfrsf14,Rbm43,Slamf7,Phf11a,Ciita,Kat2b,Stxbp1,Samd9l,Il18bp,Pla2g4a,Nfkbia,Nlrc5 |
| 6.061e-37 | -83.39 | MODULE_45 | MSigDB lists | MODULE_45 | 542 | 139 | 15632 | 1249 |
Atp11a,Psmb10,Plk3,Mvp,Tnfaip3,Sla,Cd14,Csf3r,Bcl6,Ifi209,Cd302,Tnf,Stat5a,Slc16a3,Fgl2,Ifi44,Il2rg,Il1b,Sp110,Nfkb2,Lcp2,Serpine1,Ccr1,Plek,Pde4b,Fcgr4,Dusp6,Psd4,Ccl5,Sdc1,Fpr2,Cdk5r1,Ifi214,Hk3,Ifi207,Cd34,Trp53i11,Aoah,Spn,Syk,Sod2,Bcl2a1b,Vcan,Cpd,Fcgr2b,Ctsc,Ifi204,Ifit3b,Lyn,Rac3,Pim2,Mmp9,Oasl1,Itga5,Nfil3,Adam19,Rel,Lmo4,Mndal,Atm,S100a8,Tnfrsf1b,Ikbkg,Mmd,Ifi211,Isg20,Nfkbib,Ppp4r2,Slpi,Stat2,Fgr,Sell,Lif,Hck,Gbp2,Psmb9,Ifi205,Slc2a1,Ifi213,Casp1,Cst7,Bcl2a1d,Pim1,Tgfbi,Ptafr,H2-Ab1,Cd55,Glrx,Pf4,Bcl2a1a,Plcl2,Il1rn,Tnfsf10,Cd86,Slc31a2,Nampt,Junb,Ifit1bl2,Gch1,Dgka,Hap1,Stx11,Ube2l6,Tlr1,Nmi,Ifi208,Ccnd2,Il4ra,Tap1,Pfkfb3,Htr2a,Gng11,Zyx,Cx3cr1,Ifit1bl1,Slc7a11,Ccr3,Ikzf1,Igsf6,Irf1,Tlr2,Pik3cd,Ier3,Acsl1,Ifi35,Il13ra1,Stat1,Tnfaip2,Hcls1,Itgal,Ifit3,Casp4,Psmb8,Birc3,Stat4,Ifi203,Rasgrp1,Plscr1,St3gal5 |
| 6.306e-37 | -83.35 | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_ELK1_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_ELK1_KO_DP_THYMOCYTES_UP | 169 | 74 | 15632 | 1249 |
Cx3cl1,Ifi214,Rtp4,Ddx60,Ifi207,Angpt1,Samhd1,Phf11c,Zc3hav1,Tap1,Il27,Phf11a,Adar,Pnpt1,Rbm43,Znfx1,Ifit1bl1,Nlrc5,Eif2ak2,Parp9,Parp14,Ifi204,Irf1,Phf11d,Ifit3b,Ifi35,Egr3,Stat1,Oasl1,Ifit3,Mndal,Ogfr,Rnf31,Trim56,Oas1a,Xaf1,Tdrd7,Ifi203,Trim21,Ifi211,Plscr1,Psme2,Stat2,Usp18,Ddx58,Sphk1,Dtx3l,Isg15,Agtrap,Pml,Nod1,Myd88,Ifi209,Oas3,Ifi205,Ifi213,Phf11b,Ifit2,Rsad2,Oaf,Ifi44,Rab11fip1,Usp42,Nr4a3,Herc6,Oas1g,Rtn1,Sp110,Cmpk2,Gtpbp2,Irf7,Ifit1bl2,Parp12,Ifi208 |
| 6.460e-37 | -83.33 | regulation of catalytic activity | biological process | GO:0050790 | 2089 | 296 | 20694 | 1406 |
Cflar,Ppp6r1,Dusp8,Il6,Dusp1,Hif1a,Psme2,Ccnd2,Bmp2,Thbs1,Plek,Prnp,Oas1g,Nfkb1,Ppp2r5a,Psmd10,Cdk5r1,Prkce,Tnfsf14,Ccnd1,Ikbkg,Asap3,Casp3,Pmaip1,Trib3,Ppp2r3a,Il1b,Mdm2,Mlkl,Psme1,Pdgfc,Arhgap26,Rffl,Cacna1d,Kitl,Mdfic,Cx3cl1,Ubash3b,Nlrc5,Dusp6,Casp8,Cdkn1a,Sdc4,Gch1,Ift57,Nck1,Met,Tnfsf10,Rgcc,Egr1,Tagap,Dnajb4,Rcan1,Cd55,P2ry13,Cst7,Mefv,Gadd45b,Spred3,Il1rn,Il12b,Agrn,Dusp4,Mmp25,Gdf15,Bcl6,Ppp1r15a,Tor1aip2,Tnfsf15,Lpar1,Lrch1,Dnaja2,Serpina3f,Pdgfb,Ptafr,Vcan,Arg2,Flt1,Oas1a,Fpr2,Dock10,Map2k1,Cox17,Src,Bcl2l11,Stat3,Rictor,Trib1,Tnfaip3,Cycs,Ripk3,Cd200,Adar,Crkl,Rap1gap2,Rin2,Errfi1,Spint2,Nlrc4,Jak2,Tlr6,Prdx5,Timp1,Stat1,Rgs14,Zc3hav1,Nlrp3,Ahsa1,Ranbp2,Ppm1k,Map3k8,Eif2ak2,Ccl7,Socs1,Phactr4,Dcun1d3,Ppp2r1b,Rnf34,Birc3,Psmb8,Psmb9,Tlr9,Adrb2,Arrdc4,Apaf1,Slamf8,Fcgr1,Ppp1r14b,Oas3,Ccl2,Dnajb2,Ccng2,Spry2,Dock4,Dennd1b,Csf1,Antxr1,Hspa2,Tor1aip1,Birc2,Dusp16,Sipa1l1,Ptk2,Ppp4r2,Nr1h3,Oas1b,Ccl9,Htr2a,Myc,Pde5a,Ccl8,Ptpn2,Fzd5,Dcp1a,Pdgfrb,Bcl2a1d,Oasl2,Ksr1,Abr,Mmd,Ptgs2,Slpi,Ralgds,Acsl1,Higd1a,Adora2b,Rgs3,Dusp2,Ppp2r2a,Marf1,Ppp1r12b,Rap2c,Rapgef2,Fam72a,Hsph1,Plscr1,Hspa1b,Tank,Dusp5,Lyn,Cav1,Ahr,Tbc1d13,F11r,Htr2b,Lmo4,Hp,Cnn3,Lgals9,Hhex,Pik3r6,Arf4,Ccl22,Mmp9,Sirt1,Jun,Sod2,Fam162a,Daxx,Ccl3,Oasl1,Mapkbp1,Tnf,Syk,Tpx2,Ric1,Sh3bp4,Ccl4,Pml,Ccl12,Ccnj,Rasgrp1,Pik3r5,Angpt1,Cdkn2d,Nod1,Irs2,Kat2b,Crim1,Uchl1,Icam1,Serpinb9,Ccl5,Rbl1,Cd40,Igf1r,Map3k6,Fgr,Wars,Cd74,C3,Parp3,Tlr1,Oas2,Tbc1d1,Aida,Malt1,Actb,Nqo1,Irgm2,Mul1,Ripk2,Parp9,Mvp,Serpinb6b,Nos2,Tab2,Nek6,Spred1,Traf2,Casp1,Ccne1,Ptprj,Map4k4,Casp4,Cdc42ep2,Pim1,Uaca,Sele,Rgs1,Gfi1,Notch1,Rhoh,Serpinb9b,Irak2,Il18,Adora2a,Serpina3g,Aim2,Atp2b4,Cenpe,S100a8,Map2k4,Plaur,Ppp1r15b,Nr4a1,Hdac1,Mtcp1,Nod2,Adap2,Serpine1,Fas,Pkp4,Lrp8,Dnaja1,Prkar2b,Elmod2,Edn1,Serpinb2,Stap1,Rhoc,Gadd45g,Irak3,Dtx3l,Gclm,Zfp36 |
| 6.842e-37 | -83.27 | positive regulation of nitrogen compound metabolic process | biological process | GO:0051173 | 3110 | 389 | 20694 | 1406 |
Ell2,Ccl7,Glipr2,Cenpj,Mecp2,Vegfc,Dcun1d3,Maml2,Parp14,Ezr,Spic,Slc9a1,Fcgr1,Apaf1,Tlr9,Pf4,Aff1,Spry2,Csrnp1,Birc2,Klf2,Zeb1,Ccl9,Rnf19b,Plagl2,Dcp1a,Pde5a,Myc,Htr2a,Lpar1,Mafg,Ptafr,Klrk1,Pdgfb,Hcls1,Tfec,Egr3,Src,Stat3,Tnks1bp1,Maff,Cysltr2,Ripk3,Trib1,Cycs,Stat1,Nlrc4,Crkl,Pou2f2,Cx3cl1,Mdfic,Kitl,Kdr,Egr2,Nlrc5,Arid5a,Fcgr2b,Met,Myd88,Serp1,Zfp281,Ift57,Egr1,Rgcc,Notch2,Il1rn,Kdm6b,Txn1,Gadd45b,Ppp1r15a,Bcl6,Mmp25,Gdf15,Jag1,Ciita,Cflar,Psme2,Ccnd2,Hif1a,Itga5,Il6,Ctsc,Rel,Prnp,Fbxo4,Plk2,Thbs1,Prdm9,Grk3,Ccnd1,Psmd10,Nr4a3,Crlf3,Relb,Casp3,Gja1,Ikbkg,Hmga2,Ppp2r3a,Mapkapk2,Fubp1,Pdgfc,Psme1,Mdm2,Aim2,Ets2,Mov10,Ptger4,Atp2b4,Acvr1,Hinfp,Plaur,Nr4a1,Tnfsf4,S100a8,Hdac1,Lrp8,Nod2,Stap1,Hivep3,Cop1,Zfp36,Gadd45g,Nos2,Tab2,Parp9,Ifna4,Irgm2,Nmi,Ptprj,Ass1,Tnfsf8,Icosl,Gcnt2,Csf3,Map4k4,Pim1,Tlr2,Uaca,Notch1,Pid1,Tiparp,Irak2,Ccl3,Sod2,Fzd1,Ccl4,Stat4,Syk,Eya4,Pim2,Ccr1,Pml,Pik3r5,Ccl5,Nod1,Ifnb1,Jdp2,Phip,Nox1,Map3k6,Psip1,Igf1r,Larp1,Tlr1,Cd74,C3,Malt1,Junb,Ankib1,Ahrr,Fos,Higd1a,Acsl1,Atm,Cd80,Hspa1b,Tank,Fam129a,Timeless,Cd38,Ahr,Clcf1,Lyn,Ncoa7,Tnip1,Htr2b,Ptch1,Lmo4,Helz2,Pik3r6,Hhex,Irf8,Ier3,Arf4,Plagl1,Eif2ak2,Pnpt1,Map3k8,Stat5a,Plekhn1,Rbpms,Arid4a,Ifna2,Birc3,Mllt6,Ccl2,Batf,Med21,Nfkbia,Adrb2,Arrdc4,Csf1,Nupr1,Il15,Gsap,Dnajb2,Rhoq,Hspa2,Spen,Antxr1,Ifrd1,S1pr2,Etv6,Fosb,Nr1h3,Ptk2,Fzd5,Cebpd,Pdgfrb,Ccl8,Wdr43,Tnfsf15,Flt1,Lif,Eif4g2,Map2k1,Fpr2,Stat2,Peli1,Bcl2l11,Nr3c1,Ddx58,Hmgn3,Irf7,Tnfaip3,Inhba,Rictor,Jak2,Tlr6,Sphk1,Tcea1,Scimp,Nlrp3,Zc3hav1,Tnfrsf1b,Rnf139,Plac8,Etv5,Sdc4,Cdkn1a,Casp8,Nampt,Acvrl1,Tnfsf10,Nck1,Ifna6,Rnf19a,Tmem67,Il12b,Agrn,Mefv,Ednrb,Tra2a,Tnfrsf8,Mid1,Acvr1b,Nfkb2,Bmp2,Lhx2,Cdk5r1,Prkce,Tnfrsf14,Ppp2r5a,Nfkb1,Ifnar1,Tlr3,Il1b,Trib3,Pmaip1,Polr2g,Tet2,Ifna1,Mlkl,Btg2,Hspa1a,Cenpe,Plpp3,Irf2,Ppp1r15b,Map2k4,Cx3cr1,Il10,Irf1,Nsd3,Fas,Mtcp1,Hmga1,Edn1,Sema4c,Med13,Mmp14,Irf4,Dtx3l,Rnf14,Mul1,Ripk2,Lrp4,Traf2,Ifna5,Nek6,Ldlr,Jarid2,Casp1,Hivep2,Casp4,Marco,Gfi1,Zc3h12a,Il18,Ythdf1,Plk3,Mapkbp1,Tnf,Il1a,Daxx,Tcf4,Pcgf5,Jun,Fam162a,Bambi,Tpx2,Cited2,Ccl12,Rasgrp1,Taf4b,Sertad3,Atf3,Ikzf1,Angpt1,Il27,Icam1,Kat2b,Jmjd6,Dr1,Mycl,Mtdh,Cd40,Gclc,Parp3,Pou3f1,Max,Arid5b,Ptgs2,Mmd,Bcl9,Ier2,Ksr1,Casz1,Nfil3,Klf6,Rap2c,Adora2b,Plscr1,Hsph1,Rapgef2,Spn,Pbx1,Trim30a,Spire1,Cav1,Klf7,Osm,Sqstm1,Lgals9,Mmp9,Sirt1,Ccl22,Arel1 |
| 8.863e-37 | -83.01 | CHEN_METABOLIC_SYNDROM_NETWORK | MSigDB lists | CHEN_METABOLIC_SYNDROM_NETWORK | 1126 | 217 | 15632 | 1249 |
Nrp2,Vasn,Plek,Myadm,Plekha4,Lcp2,Slfn4,Pilrb1,Vcam1,Nfkb2,Epsti1,Acp2,Tmem229b,D1Ertd622e,Tnc,Dock10,Cers6,Tnf,Phf11b,Txnrd1,P2ry13,Traf5,Cd14,Hvcn1,Ch25h,Cd74,Tulp3,Fabp7,Slpi,S100a8,Mndal,Adap2,Lrrc25,Fscn1,Ccl4,Adam19,Frmd6,Dram1,Lyn,Rin2,Psd,Vcan,Plac8,Syk,F10,Phf11a,Slc48a1,Ifi207,Stxbp1,Ifi214,P2ry14,Ifi208,Antxr1,Slc2a6,Hk2,Uba7,Slc7a8,Gch1,Cd86,Slfn3,Osbpl3,Prkx,Lacc1,Glrx,Tfec,Smox,Arl5c,Dusp5,Clec4d,Acvrl1,Ifi213,Parp8,Ifnar1,Casp1,Ifi205,Ripk3,Clcn5,Mcmbp,Rhoc,Sphk1,Plscr1,Trip13,Pla2g7,Ccrl2,Layn,Hcls1,Tnfaip2,Plekhn1,Ebi3,Tlr2,Sdc2,Il18bp,Nqo1,Ccl12,Cyfip1,Msr1,Jun,Pde3b,Samhd1,Ppm1l,Icosl,H2-Aa,Stxbp3,Car13,Mmp13,Fzd5,Cd274,Pdgfrb,Cxcl1,Ikbke,Ralgds,Plat,Htr2b,Snn,Slc31a1,Phyh,Map3k8,Frmd4a,Ubtd2,Batf2,Ifit2,Abcc5,Phldb1,Tpst1,Ifi209,Csf3r,Batf,Cd38,Olfml3,Aim2,Mcoln2,Srxn1,Ifi211,Usp12,Slamf9,Oasl1,Ptgir,Cacnb3,Tnip3,Ifi204,Mthfd2,Ifit3b,Pla2g4a,S1pr2,Gsdmd,Gadd45b,Ppp1r14b,Spic,Nlrc4,Hmga1,Cd34,Pilrb2,Pilra,Slamf7,Lpcat2,Hk3,Spred1,Olr1,Evl,Ubash3b,Aldh1b1,Rgl1,Slc4a7,Plk2,Samsn1,Igsf8,Plaur,Gng12,Pf4,Abcc4,Oas1g,Slamf8,Lox,Tbc1d1,Slc15a3,Egr2,Apobec3,Dse,Ttc39c,Rgs14,Cd83,Crlf3,Bfar,Relb,Rhoh,Cd180,Rab19,Slco3a1,Htra1,Oas1a,Stat4,Casp2,Ifi203,Ltbp2,Irf8,Itgal,Ifit3,Tnip1,Rgs1,Agpat4,Nlgn2,Endod1,Dck,Filip1l,Ms4a6d,Phf11d,Rcn1,Mefv,Fam111a,Igsf6,Cxcl14,Fos,Fcgr1,Phf11c,Atf3,Pgs1,Abr |
| 1.036e-36 | -82.86 | MOSERLE_IFNA_RESPONSE | MSigDB lists | MOSERLE_IFNA_RESPONSE | 35 | 34 | 15632 | 1249 |
Epsti1,Cmpk2,Tnfsf10,Ifi204,Cxcl10,Ifit3b,Oas1g,Stat1,Oasl1,Oas1a,Ifi203,Oas2,Ifi211,Ifi208,Ifit3,Cd274,Mndal,Ifit1bl2,Ifi207,Zc3hav1,Usp18,Ddx58,Ifi214,Ifih1,Rtp4,Ddx60,Rsad2,Samd9l,Ifi44,Ifi209,Ifi205,Ifit1bl1,Ifit2,Ifi213 |
| 1.207e-36 | -82.71 | positive regulation of immune response | biological process | GO:0050778 | 545 | 128 | 20694 | 1406 |
Ptprj,Trim12c,Il18rap,Ifi203,Pvr,Fpr2,H2-Ab1,Peli1,Icosl,Treml4,Ikbke,Wdfy1,Tifa,Parp9,Ifi208,Ripk2,Hlx,Irgm2,Traf2,Usp12,Ptafr,Raet1e,Klrk1,Mndal,Nlrp3,Zc3hav1,Zc3h12a,Il18,Cd300lf,Irak2,Ifi211,Ddx58,Clec4e,Tlr2,H2-Q4,Themis2,Irf7,Il12rb1,H2-T22,Lcp2,Tlr6,Nlrc4,Zbp1,Crkl,Tnfsf4,H60b,H2-Q6,Irf1,Fcgr1,Nfkbia,Tlr9,Aim2,Stat5a,Cmklr1,Nr1h3,Nectin2,C1ra,Ddx60,Fzd5,Irak3,Dennd1b,Il15,H2-Q7,Tap2,Nod2,Nfkbid,Stap1,Ifih1,Cd86,Adora2b,H2-M2,Plscr1,Cd38,Spn,Cacnb3,Bcl2a1d,Il6,Il1b,Dhx58,Cd274,Lgals9,Mapkapk2,Sirt1,H2-T24,C1rl,Ifi209,Nr4a3,Clcf1,Prkce,Cav1,Lyn,Tnfrsf14,Il4ra,Tnip1,Acod1,H2-T10,Ifi205,Tlr3,Nfkbiz,Rasgrp1,Arid5a,Fcgr2b,Irgm1,Myd88,Tnf,Ifi204,Rsad2,Stxbp1,Nlrc5,Syk,Il12b,Cgas,Tlr1,C3,Cd55,Cd74,Malt1,Cd14,Fpr1,Pde4b,Rnf31,Ifi214,Rgcc,Tnip3,Hk1,Fgr,Ankrd17,Cd40 |
| 1.241e-36 | -82.68 | response to virus | biological process | GO:0009615 | 221 | 79 | 20694 | 1406 |
Ifit1,Gbp2b,Cxcl10,Oas1a,Cxcl9,Il6,Ifit1bl1,Ikbke,Oasl2,Irgm2,Ifit2,Ifna4,Parp9,Bcl2l11,Plscr1,Slfn8,Treml4,Ifit3b,Samhd1,Cd86,Stat2,Isg20,Lcn2,Mx1,Ifnar1,Ifit1bl2,Stat1,Rtp4,Tlr3,Zbp1,Ddx58,Adar,Trim30a,Mx2,Oas1g,Irf7,Ifna1,Zc3h12a,Trim34a,Isg15,Nlrp3,Dhx58,Zc3hav1,Lgals9,Ifna2,Apobec3,Slfn9,Eif2ak2,Oasl1,Tnf,Rsad2,Trim12a,Shfl,Oas3,Myd88,Irf1,Tlr9,Ifna6,Tnfsf4,Ifit3,Ago3,Ddit4,Irf2,Pml,Trim56,Ifih1,Cd40,Tagap,Ifnb1,Oas2,Ifitm1,Dtx3l,Irak3,Bnip3,Il12b,Nt5c3,Oas1b,Cgas,Ddx60 |
| 1.313e-36 | -82.62 | GO_REGULATION_OF_RESPONSE_TO_STRESS | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_STRESS | 1370 | 246 | 15632 | 1249 |
Trafd1,Plaur,Serpinb2,Thbs1,Elmod2,Serpinb9,Grina,Zc3h12a,Ptger4,Ifna6,Pdgfb,Slc7a2,Sesn3,Relb,Mdfic,Hck,Bfar,Trim12c,Socs1,Calcrl,Stat2,Cd180,Ddx58,Il1a,Hif1a,Malt1,Psma6,Mdm2,Fut8,Casp3,Birc2,Hspa1a,Tank,Src,Hsph1,Gfi1,Trem1,Tnip1,Ier3,Mefv,Adrb2,Stat1,Nox1,Met,Eef1e1,Ifi203,Rasgrp1,Sirt1,Htra1,Casp4,Birc3,Psmb8,Rabgef1,Tap1,Chmp4b,Atp2b4,Pnpt1,Adar,Nlrp3,Abr,Nod2,Prkce,Edn1,Irf4,Zyx,Psmd10,Bcl2l11,Nlrc5,Ezr,Ifit1bl1,Map3k6,Il1b,Ikbke,Plat,Il18,Nr4a3,Adora2b,Psmb6,Ripk2,Hp,Serpine1,Irf7,Map2k1,Osm,Fzd5,Hopx,Gja1,Irak3,Ifna2,Ccl3,Myd88,Psmb10,Rnf135,Ifih1,Tab2,Aim2,Ifi209,Ankrd17,Ifi204,Tnip3,C3,Tlr9,Rictor,Ifi211,Nos2,Cav1,Tnfrsf1b,Ednrb,Zc3hav1,Enpp4,Spred1,Clec4e,Tspo,Il27,Cd34,Nr1h3,Cx3cl1,Pikfyve,Cdk5r1,Ubash3b,Cdkn2d,Usp25,Nek6,Parp9,Gadd45g,Mid1,Ifna5,Scarf1,Bnip3,Pla2g4a,Hmga1,Ptpn2,Nlrc4,Gadd45b,Dek,Il12b,Clec4d,Ptgs2,Uchl1,Traf3ip2,Larp1,Cd55,Tyk2,Ifi208,Tlr1,Nmi,Pik3r6,Cd86,Map4k4,Gch1,Ifit1bl2,Txn1,Daxx,Bmp2,Nod1,Fgr,Pml,Nfkbil1,H2-Q7,Psme1,Dbnl,Ifi205,Psmb9,Ifnar1,Casp1,Ifi213,Igf1r,Kdr,Tlr2,Irf1,Aida,Socs3,Itpkc,Tnfsf4,Fignl2,Leng9,Smpdl3b,Pla2g7,Plscr1,Marco,Il10,Clec4n,Samhd1,Ifna1,Prdx1,Plau,Trim13,Mapkapk2,Tlr6,Myc,Peli1,Ccl2,Il6,Ccl12,Cx3cr1,H2-Q4,Nfkbia,Irak2,Tlr3,Il12rb1,Wdfy1,Atp6v1d,Ppp1r15a,Ccl5,Fcgr4,Plek,Tnfaip3,Cd14,Cd74,Usp18,Rsad2,Dhx58,Sele,Errfi1,Bcl6,Traf2,H2-Q6,Tnf,Ccl4,Jak2,Lyn,Rab20,Sema4c,Psme2,Ppp4r2,Mndal,Casp8,Nfkb1,Ikbkg,Ppp1r15b,S100a8,Atm,Ifi207,Il15,Mul1,Ifi214,Nck1,Ddx60,Ifnb1,Phlpp1,Dnaja1,Sod2,Sqstm1,Syk,Spn,Eif2ak2 |
| 2.711e-36 | -81.90 | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN | MSigDB lists | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN | 186 | 77 | 15632 | 1249 |
Nod2,Scarf1,Edn1,Stap1,Dnaja1,Rnf114,Tap1,Phf11c,Ciita,Il15,Phf11a,Adar,Slamf7,P2ry14,Ddx60,Usp25,Tdrd7,Isg20,Plscr1,Psme2,Casp4,Lap3,C1rl,Psmb8,Vrk2,Jak2,Rbms1,Phf11d,Irf1,Aida,Rcn1,Lyn,Mthfd2,Rab20,Casp7,Ppa1,Stat1,Rsad2,Cers6,Stat3,Ifi44,Rnf24,Psmb9,Rhbdf2,Phf11b,Sp140,Gbp2,Mvp,Ddx58,Icam1,Ifih1,Isg15,Socs1,Prrg4,G3bp2,Wars,Parp12,Stx11,Trim26,Nmi,Lcp2,Vps54,Ascc3,Irf7,Plek,4930523C07Rik,Junb,Gch1,Il15ra,Trafd1,Sp110,Tnfsf10,Slamf8,Pim1,Cxcl10,Herc6,Rnf19b |
| 2.887e-36 | -81.83 | GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | 413 | 118 | 15632 | 1249 |
Tnfrsf14,Samhd1,Ciita,Ifna1,Fcgr1,Adar,Ccl22,Il4ra,Lrp8,Egr1,Irf4,Ccr3,Il6,Ccl2,Psmd10,H2-Q4,Ifit1bl1,Cx3cr1,Ccl12,Flrt3,Socs7,Xcr1,Clcf1,Irf1,Acsl1,Tnfsf4,Ebi3,Ifi35,Il13ra1,Stat1,Socs3,Sirt1,Oas1a,Ccrl2,Irf8,Ifit3,Tnfsf14,Psmb8,Birc3,Hck,Gbp2,Tnfrsf8,Il1a,Icam1,Stat2,Socs1,Trim12c,Isg15,Irf2,H2-Q7,Psme1,Pml,Psma6,Cish,Psmb9,Birc2,Cd40,Ifnar1,Il15ra,Pf4,Cmklr1,Il12b,Cxcl10,Ptafr,H2-Ab1,Oas1g,Csf3,Oas2,Tyk2,Ifna6,Tnfsf15,Ifit1bl2,Cx3cl1,Fas,Mid1,Ifnb1,Ifna5,Jak2,Ccl4,Ifit3b,Oasl1,Xaf1,Csf1,Trim21,Isg20,Psme2,Tnfrsf1b,Ccl3,Irak3,Ifna2,Cd74,Psmb10,Aim2,Rsad2,Stat3,H2-Q6,Traf2,Oas3,Csf3r,Ifit2,Tnf,Stat5a,Il1b,Cxcl1,Vcam1,Irak2,Il2rg,Psmb6,Il12rb1,Cxcl2,Trim26,H2-Aa,Flrt2,Irf7,Osm,Ccr1,H2-Eb1,Ccl5 |
| 3.010e-36 | -81.79 | GSE3982_CTRL_VS_LPS_4H_MAC_DN | MSigDB lists | GSE3982_CTRL_VS_LPS_4H_MAC_DN | 191 | 78 | 15632 | 1249 |
Mndal,Cav1,Irf8,Sema3c,Rel,Ifi203,Dcp1a,Tdrd7,Jag1,Usp12,Oas1a,Isg20,Ifi211,Mthfd2,Ifi204,Irf1,Stat1,Oasl1,Ifi35,Casp7,Cflar,Tiparp,Pik3r5,Agrn,Ezr,Spsb1,Hivep2,Gadd45b,Cox17,Chst11,Ifi214,Fas,Ifi207,Cd80,Adar,Ccl5,Pde4b,Plek,Maff,Wars,Ifi208,Gpr132,Arid5b,Rcan1,Kcna3,Oas1g,Zc3h12a,Cd55,Pgk1,Clic4,Nfkb2,Il1rn,Dek,Birc2,Cd40,Ifi209,Ifi205,Psmb9,Klf6,Ifi213,Ifit2,Cebpd,Itgb8,Ifi44,Sphk1,Ifih1,Traf1,Stat2,Kmo,Usp18,Hif1a,Nupr1,Ube2e1,Irf2,Tnfaip3,Plagl2,Cd38,Myd88 |
| 3.262e-36 | -81.71 | GSE36009_UNSTIM_VS_LPS_STIM_DC_UP | MSigDB lists | GSE36009_UNSTIM_VS_LPS_STIM_DC_UP | 177 | 75 | 15632 | 1249 |
Atf3,P2ry14,Ciita,Zbtb5,Sgcb,Zbp1,Rbm43,Adar,Tap1,Samhd1,Ahr,Nlrc5,Rnf114,Gpr18,Ptpn2,Zyx,Slfn8,Parp14,Rai14,Taf4b,Gadd45g,Casp7,Stat1,Denr,Ppa1,Dr1,Rap2c,Tagap,Lhx2,Pmepa1,Gbp7,Ksr1,Trim14,Psme1,Rab19,Stat2,Gbp3,Sphk1,Rnf34,Nod1,Traf5,1600014C10Rik,Gda,Daxx,Plod3,Apobec3,Psmb9,1110038F14Rik,Stat3,Pnp2,Rab9,Batf2,Mafk,Naa25,Parp3,Traf3ip2,Slamf8,Tapbpl,Tnfsf10,Gcnt2,Slfn9,Hcar2,Nampt,4930523C07Rik,Ccr1,Arid4a,Ccnj,Card6,Cd274,Klf2,Golga3,Inpp5b,Nmi,Noc4l,Bst1 |
| 3.423e-36 | -81.66 | regulation of cellular process | biological process | GO:0050794 | 10729 | 953 | 20694 | 1406 |
Agrn,Traf3ip2,Ccdc88b,Ednrb,Tra2a,Carhsp1,Ifi214,Stxbp3,Brd2,Ogfrl1,Pla2g4a,Etv5,Abcc1,Sdc4,Phf6,Rbbp8,Casp8,Nampt,Pikfyve,Acvrl1,Rnf19a,Tmem176a,Mt2,P2ry2,Arhgap26,Sik3,H2-Aa,Pim3,Trib3,Polr2g,Gpr141,Rfx5,Keap1,Ppp2r5a,Ppm1l,Tnfrsf14,Oas1g,Ifi205,Slc30a4,Plat,Tlr3,Bmp2,Casp2,Zbtb5,Tnfsf9,Lhx2,Cnn2,Tnfrsf8,Saa3,G3bp2,Acvr1b,Dusp1,Etv6,Kdm5b,Fosb,Rac3,Ptk2,Gda,Ptpn2,Fzd5,Nupr1,Csf1,Gsr,Hcar2,Igsf9,Gpr84,Ccng2,Mob3b,Dnajb2,Sipa1l1,Rhoq,Hspa2,Antxr1,Spen,Dgkh,Sco1,D1Ertd622e,Oas3,Batf,Ccl2,Med21,Slc30a1,Arrdc4,Pnpt1,Slfn1,Aebp2,Apobec3,Tnc,Zc3hav1,Akt3,P2ry14,Tnfrsf1b,Rnf139,Itga9,Plac8,Sp140,Ifi211,Ddx58,Hmgn3,Vasn,Tnfaip3,Irf7,Timp1,Jak2,Errfi1,Rap1gap2,Sphk1,Rab19,Pdk3,Trim12c,Eif4g2,Map2k1,Odc1,Fpr2,Bcl2l11,Nr3c1,Psma6,Tnfsf15,Oas1a,Usp12,Arg2,Lif,Parp3,Pou3f1,Nqo1,Max,Rpgrip1l,Lipg,Fscn1,Aida,Insl6,Slc16a1,Jmjd6,Igf2bp2,Dync1h1,Mtdh,Nlgn2,Mycl,Cd40,Rbl1,Rasgrp1,Rras2,Ccl12,Acpp,Asah2,Taf4b,Parp10,Sertad3,Angpt1,Ikzf1,Mxd1,Il27,Pilrb1,Plk3,Tnf,Mapkbp1,Tcf4,Pcgf5,Stxbp1,Cd83,Etv3,Sirt1,Arel1,Ccl22,Cxcl11,Trim30a,Myadm,Spire1,Cav1,Itpr1,Acod1,F11r,Riox2,Rap2c,Cd86,Marf1,Tax1bp1,Rapgef2,Mier3,Ptgs2,Ifi213,Gna15,Bcl9,Oasl2,Ifit2,Ier2,Ralgds,Cyfip1,Rhoc,Ogfr,Ccr3,Ptgir,Irf4,Lnpep,Svbp,Itga4,Pkp4,Rubcnl,Fas,Frmd6,Serpinb2,Edn1,Trip13,Ppp1r15b,Irf2,Map2k4,Dach1,Rab21,Il10,Irf1,Serpina3g,Fchsd2,Plpp3,Scarf1,Slfn2,Chmp4b,Ythdf1,Gpr18,Frmd4a,Osgin2,Crbn,Marco,Foxp4,Marcksl1,Dgka,Ccne1,Ifi203,Hap1,Casp1,Casp4,Trim26,Rhbdf2,Wdfy1,Tmod3,Mvp,Mul1,Ripk2,Usp25,Tmem178,Rnd1,Txn1,Il1rn,Kdm6b,Cgas,Spred3,Gadd45b,Cnot4,Rcan1,Mark2,Ppp1r15a,Bcl6,Dusp4,Mmp25,Pmepa1,Egr1,Rgcc,Zhx2,Calcrl,Cxcl14,Dnajb4,Rapgef5,Eno1,Vcam1,Kmt5a,Mafk,Myd88,Met,H3f3b,Kitl,Pilra,Plaat3,Egr2,Gfpt1,Nlrc5,Ubash3b,Dtx2,Ppp2r3a,Hmga2,Dram1,Fubp1,Pdgfc,Palld,Slc7a2,Tnfsf14,Psd4,Pcx,Relb,Gja1,Itgav,Hk2,Samhd1,Ctsc,Gem,Rel,Sema4a,Prnp,Plk2,N4bp1,Cd34,Grk3,Mamld1,Vasp,Sap30,Cflar,Il6,Clec2d,Ccl9,Olfr56,Ppp4r2,Myc,Htr2a,Ntng2,Ccrl2,Triobp,Birc2,Pde1b,Klf2,Ddit4,Sdc2,Scyl2,Glrx,Ezr,Spic,Tlr9,Apaf1,Pf4,Ell2,Rhou,Card6,Ap3b1,Ccl7,Glipr2,Cxcl1,Znrf3,Iigp1,Vegfc,Ranbp2,Swap70,Hk3,Maff,Adar,Il12rb1,Stat1,Bcor,Flrt3,Nlrc4,Spint2,Rin2,Hat1,Crkl,Sec24a,4932438A13Rik,Kcnj2,Tfec,Egr3,Ggct,Stat3,Gpr68,Smpdl3b,Sema3c,Ikbke,Batf2,Piezo1,Lpar1,Mafg,Xaf1,Dst,Ebi3,Pdgfb,Tlr1,Malt1,Junb,Pde4b,Oas2,Ccl5,Trim14,Serpinb9,Cdkn2d,Ifnb1,Phip,Fgr,Vrk2,Map3k6,Igf1r,Psip1,Eya4,Brwd3,Pml,Col4a2,Bfar,Oasl1,Ccl3,Sod2,Ccl4,Stat4,Sh3bp4,Ric1,Pde3b,Pik3r6,Txnrd1,Hp,Klf3,Fam20c,Clcf1,Chst11,Lyn,Sell,Ncoa7,Slc7a11,Il4ra,Tnip1,Kremen1,Htr2b,Slc39a4,Rims3,Rab32,Adgrl2,Cdyl,Fam129a,Cd38,Sat1,Bcl2a1d,Nes,Cd80,Itgb8,Nectin2,Hivep3,Ctla2a,Radx,Trim21,Nr4a1,Tnfsf4,S100a8,Adgrg6,Ust,Aim2,Adora2a,Mmp13,Atp2b4,Ptger4,Mov10,Rhoh,Tiparp,Cd300lf,Rnd3,Hmox1,Plpp1,Uaca,Ptprj,Nmi,Ass1,Nfkbie,Xcr1,Gng4,Icosl,Cdc42ep2,Dyrk2,Map4k4,Mtus1,Cyth3,Ifna4,Il12b,Mefv,P2ry13,Samsn1,Cd14,Ifitm1,Bnip3,Srgn,Sinhcaf,Tnip3,Tmem67,Mosmo,Clic4,Daam1,Katna1,Ifi207,Cdkn1a,Spata13,Zfp513,Gpr35,Agtrap,Tnfsf10,Ifna6,Nck1,Inpp5b,Rffl,P2ry12,Dusp6,Bcl2a1b,Cacybp,Il1b,Isg15,Sla,Tet2,Pmaip1,Ifna1,Acp5,Btg2,Mlkl,Cdk5r1,Prkce,4930453N24Rik,Nfkb1,Ifnar1,Nfkbiz,Nmral1,Plek,Nrp2,Cpeb4,Mid1,Lox,Il2rg,Perm1,Nfkb2,Prag1,Prkx,Nr1h3,Tle3,Rab3ip,Pdgfrb,Cebpd,Ccl8,Ociad1,Gng11,Il15,Gsap,Col18a1,S1pr2,Ifrd1,Birc3,Mllt6,Igsf8,Ppp1r14b,Slamf8,Dcp2,Adrb2,Gtpbp2,Nfkbia,Evl,Pdpn,Socs1,Gpr85,Plagl1,Eif2ak2,Map3k8,Stat5a,Rnf34,Plekhn1,Rbpms,Socs3,Arid4a,Ifna2,Azi2,Eef1e1,Nlrp3,Scimp,Rgs14,Clec4n,Tyk2,Traf5,Dek,Inhba,Pgk1,Ptges,Rictor,Tlr6,Lcp2,Cdyl2,Zbp1,Tcea1,Dock10,Stat2,Peli1,Bcl2a1a,Phlda1,Cox17,Treml4,Wdr43,Gpc1,Asb13,Flt1,Vcan,Gclc,Il13ra1,Cd180,Abracl,Arid5b,Icam1,Hk1,Uchl1,Irs2,Kat2b,Dr1,Psd,Pfkl,Caml,Atf3,Kif9,Prdx1,Daxx,Il1a,Fam162a,Jun,Rsad2,Nsmaf,Bambi,Tpx2,Cited2,Kctd12,Cd274,Lgals9,Il15ra,Mmp9,Plcl2,Pbx1,Klf7,Osm,Dbnl,Sqstm1,Ppp1r12b,Ppp2r2a,F10,Nfxl1,Adora2b,Dusp5,Sde2,Plscr1,Pik3cd,Hsph1,Spn,Syne2,Mmd,Ksr1,Pde7b,Traf1,Hilpda,Casz1,Ddx4,Nfil3,Klf6,Slpi,Sav1,Med13,Sgk3,Phldb1,Ddx60,Mmp14,Gclm,Dtx3l,Nsd3,Hmga1,Mtcp1,Resf1,Sema4c,Cish,Socs7,Gng12,Stau1,Prkar2b,Dnaja1,Intu,Cx3cr1,Klhl25,Gk,Phlpp1,Fmnl2,Rab11fip1,Tspo,Cenpe,Cmklr1,Lnpk,Hspa1a,Kif3c,Usp42,Bst1,Serpinb9b,Trip10,Prokr1,Sele,Gfi1,Zc3h12a,Il18,Fgl2,Tomm70a,Nfkbib,Ldlr,Smg7,Il18rap,Rrs1,Jarid2,Clec5a,Hivep2,Nfkbil1,Tut7,Rnf14,Serpinb6b,Lrp4,Tifa,Hlx,Stk40,Znfx1,Mthfr,Traf2,Rilpl1,Ifna5,Nek6,Cst7,Pdlim7,Gdf15,Tagap,Rab10,Notch2,Ube2e2,Fut8,Arid5a,Gch1,Fcgr2b,Siglece,Irgm1,Serp1,Zfp281,Ift57,Dcbld2,Cx3cl1,Mdfic,Cacna1d,Kdr,Tal2,Pttg1,Mapkapk2,Psme1,Mdm2,Gpr132,Ccnd1,Nr4a3,Psmd10,Zmynd15,Crlf3,Casp3,Ikbkg,Rhof,Asap3,Ddhd1,Fbxo4,Thbs1,Mt1,Cacnb3,Prdm9,Dusp8,Jag1,Ciita,Ppp6r1,Ccnd2,Psme2,Itga5,Hif1a,Kdm4a,Kmo,Oas1b,Zeb1,Rnf19b,Dync1i2,Fcgr4,Plagl2,Dcp1a,Pde5a,Myo10,Dennd1b,Aff1,Dock4,Spry2,Csf3r,Csrnp1,Dusp16,Ifih1,Maml2,Parp14,Ppfia3,Fcgr1,Slc9a1,Hopx,Cenpj,Ppp2r1b,Mecp2,Dcun1d3,Phactr4,Tulp3,Mndal,Gnb4,Apba1,Optn,Pou2f2,Abcc4,Cd200,Mpp7,Ripk3,Cysltr2,Ncoa5,Cycs,Trib1,Tarm1,Cxcl3,Prdx5,Hcls1,Lcn2,Lst1,H2-Ab1,Hck,Src,Tnks1bp1,Serpina3f,Lrch1,Cxcl10,Ptafr,Ero1l,Ak4,Klrk1,Fabp3,C3,Cd74,Actb,Gsdmd,Fpr1,Rnf31,Sec24b,Ift22,Cxcl2,Rabgef1,Jdp2,Nod1,Nox1,Wars,Fignl2,Msr1,Tshz1,Ankrd17,Larp1,Ago3,Ccnj,Pim2,Zyx,Ccr1,Ciapin1,Rab20,Noct,Pik3r5,Milr1,Prdm1,Zswim4,Ifi204,Trim36,Fzd1,Syk,Dhx58,Hhex,Grina,Trim13,Axl,Acsl5,Irf8,Gpsm2,Ier3,Arf4,Sdc1,Ifi209,Ahr,Lmo4,Ptch1,Helz2,Dusp2,Rgs3,Stoml1,Arhgef3,Whamm,Tank,Hspa1b,Rab9,Timeless,Fam72a,Ahrr,Ankib1,Fos,Abr,Higd1a,Acsl1,Atm,Tent4a,Morc3,Cop1,Zfp36,Irak3,Gadd45g,Lrp8,Tmsb10,Carmil1,Tmem176b,Serpine1,Adap2,Pla2g7,Nod2,Flrt2,Nfkbid,Tsku,Stap1,Xrn1,Homer1,Tent2,D16Ertd472e,Sp110,Hinfp,Acvr1,Plaur,Plau,Cdc42ep4,Rgl1,Hdac1,Egln3,Ehd1,Ets2,Abcb1a,Notch1,Pid1,Rgs1,Itgal,Slamf7,Irak2,Pim1,Clec4e,Tlr2,Clec4d,Themis2,Adgre4,Klf8,Tlk2,Tnfsf8,Asns,Csf3,Gcnt2,Wdr59,Smc5,Gbp4,Tab2,Nos2,Ifi208,Parp9,Irgm2,Sesn3,Htra1,Scn1b,Spred1,Slfn3,Cxcl9 |
| 3.517e-36 | -81.64 | GSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN | 133 | 65 | 15632 | 1249 |
Stat2,Usp18,Ddx58,Ifih1,Itga4,Fgl2,Rsad2,Nr3c1,Ifi44,Psmb9,Itpr1,Swap70,Birc2,Oas3,Ifit2,Rsbn1,Nfxl1,Tnfsf10,Tmem229b,Cxcl10,Tlr3,Rapgef2,Parp12,Oas2,Ube2l6,Nmi,Tlr1,Samsn1,Irf7,Sipa1l1,Ifit1bl2,Jarid2,Slfn5,Atp11b,Samhd1,Tap1,Rnd3,Adar,Zbp1,P2ry14,Rtp4,Ddx60,Samd9l,Ikzf1,Stap1,Tgs1,Ifit1bl1,Eif2ak2,Lrrc8c,Gbp2b,Parp11,Ifit3b,Etnk1,Nox1,Stat1,Tmod3,Xaf1,Tdrd7,Casp2,Trim21,Trim14,Zeb1,Mov10,Ifit3,Rnf31 |
| 3.535e-36 | -81.63 | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM | MSigDB lists | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM | 252 | 90 | 15632 | 1249 |
Ifnb1,Ifna5,Eif2ak2,Sqstm1,Syk,Ptpn2,Irs2,Isg20,Xaf1,Ikbkg,Jak2,Oasl1,Lyn,Map2k4,Ifit3b,Stat3,Gbp9,Stat5a,Ifit2,H2-Q6,Oas3,Myd88,Ifna2,Irak3,Usp18,Tab2,Gbp3,H2-Aa,H2-Eb1,Map2k1,Irf7,Vcam1,Irak2,Nfkb2,Il1b,Crkl,Ripk2,Il2rg,Map3k8,Il18,Irf4,Peli1,Il6,Nod2,H2-Q4,Ifit1bl1,Ifna1,Ciita,Fcgr1,Adar,Egr1,Flnb,Oas1a,Psmb8,Eif4g2,Ifit3,Irf8,Gbp7,Ifi35,Kpna3,Stat1,Socs3,Irf1,Pik3cd,Gbp4,Cish,Casp1,Ifnar1,Nod1,Gbp2,Hck,Irf2,H2-Q7,Ube2e1,Pml,Stat2,Il1a,Icam1,Ddx58,Isg15,Socs1,Ube2l6,Ifna6,Uba7,Tyk2,Oas2,Ifit1bl2,Il1rn,Oas1g,Ptafr |
| 3.599e-36 | -81.61 | regulation of multicellular organismal process | biological process | GO:0051239 | 3236 | 398 | 20694 | 1406 |
Stat5a,Eif2ak2,Socs1,Pdpn,D1Ertd622e,Evl,Nfkbia,Adrb2,Slamf8,Ccl2,Il15,Hcar2,Nupr1,Csf1,Ifrd1,S1pr2,Spen,Sipa1l1,Ptk2,Tle3,Nr1h3,Kdm5b,Prkx,Rac3,Prag1,Fzd5,Ptpn2,Cebpd,Pdgfrb,Tnfsf15,Gpc1,Lif,Arg2,Flt1,Map2k1,Eif4g2,Nr3c1,Bcl2l11,Peli1,Irf7,Tnfaip3,Inhba,Pgk1,Vasn,Ddx58,Sphk1,Rap1gap2,Errfi1,Tlr6,Jak2,Timp1,Akt3,Rgs14,Zc3hav1,Nlrp3,Ifi211,Clec4n,Plac8,Tnfrsf1b,P2ry12,P2ry2,H2-Aa,Dusp6,Casp8,Etv5,Katna1,Tmem176a,Nck1,Acvrl1,Gpr35,Srgn,Mosmo,Ccdc88b,Mefv,Il12b,Agrn,Cd14,Ednrb,Il2rg,Lox,Tnfrsf8,Acvr1b,Bmp2,Lhx2,Plek,Tnfsf9,Nfkb1,Tnfrsf14,Cdk5r1,Prkce,Keap1,Nfkbiz,Tlr3,Plat,Ifi205,Ifnar1,Isg15,Il1b,Acp5,Tspo,Rab11fip1,Plpp3,Kif3c,Cmklr1,Lnpk,Rab21,Il10,Cx3cr1,Intu,Phlpp1,Irf1,Fas,Sema4c,Edn1,Ddx60,Phldb1,Mmp14,Ccr3,Sav1,Svbp,Irf4,Lnpep,Hlx,Ripk2,Mul1,Lrp4,Tmem178,Traf2,Jarid2,Casp1,Hap1,Ldlr,Nfkbil1,Casp4,Clec5a,Gpr18,Foxp4,Gfi1,Trip10,Scarf1,Tomm70a,Il18,Fgl2,Zc3h12a,Rsad2,Jun,Tcf4,Il1a,Daxx,Mapkbp1,Tnf,Cited2,Rnf135,Bambi,Acpp,Rasgrp1,Il27,Pilrb1,Ikzf1,Angpt1,Kat2b,Hk1,Icam1,Cd40,Nlgn2,Mycl,Mtdh,Dync1h1,Parp3,Aida,Lipg,Mmd,Ptgs2,Klf6,Cyfip1,Hilpda,Casz1,Adora2b,Cd86,Spn,Rapgef2,Dusp5,Osm,Cav1,Klf7,Myadm,Pbx1,Trim30a,Dbnl,F11r,Itpr1,Acod1,Il15ra,Lgals9,Cd83,Cd274,Plcl2,Sirt1,Mmp9,Cxcl1,Glipr2,Ap3b1,Hopx,Vegfc,Tulp3,Mecp2,Znrf3,Ezr,Dio2,Sdc2,Pf4,Tlr9,Slc9a1,Spry2,Dock4,Klf2,Ifih1,Csf3r,Ntng2,Dync1i2,Zeb1,Clec2d,Htr2a,Pde5a,Myc,Fcgr4,Lpar1,Klrk1,Pdgfb,Ptafr,Cxcl10,Mafg,Kcnj2,Lcn2,Hcls1,Gpr68,Sema3c,Src,Stat3,Egr3,Tarm1,Il12rb1,Trib1,Cysltr2,Ripk3,Cd200,Maff,Crkl,Flrt3,Stat1,Bcor,Mndal,Optn,Cacna1d,Kitl,Cx3cl1,Ubash3b,Egr2,Kdr,Plaat3,Fcgr2b,Gch1,Arid5a,Met,Serp1,Myd88,Notch2,Zhx2,Calcrl,Rgcc,Egr1,Mark2,Cst7,Cnot4,Il1rn,Cgas,Kdm6b,Gdf15,Bcl6,Pdlim7,Cflar,Jag1,Kdm4a,Il6,Itga5,Hif1a,Sema4a,Rel,Ctsc,Cacnb3,Cd34,Plk2,Thbs1,Prnp,Relb,Nr4a3,Ccnd1,Hk2,Itgav,Gja1,Mapkapk2,Fubp1,Hmga2,Ppp2r3a,Mdm2,Procr,Pdgfc,Ehd1,Adora2a,Aim2,Ptger4,Mov10,Atp2b4,Abcb1a,Mcoln2,Mmp13,Tnfsf4,Acvr1,Ust,Hdac1,Plau,Flrt2,Nfkbid,Nod2,Tmem176b,Serpine1,Lrp8,D16Ertd472e,Homer1,Stap1,Enpp4,Itgb8,Gadd45g,Irak3,Zfp36,Ctla2a,Nos2,Gbp4,Spred1,Scn1b,Nmi,Ptprj,Map4k4,Icosl,Csf3,Gcnt2,Tlr2,Hmox1,Clec4e,Pim1,Notch1,Fzd1,Sod2,Ifi204,Ccl3,Zswim4,Syk,Pde3b,Ccl4,Ccr1,Pml,Prdm1,Noct,Col4a2,Ifnb1,Nod1,Rabgef1,Ccl5,Igf1r,Ankrd17,Fgr,Wars,Cd74,C3,Tlr1,Oas2,Sec24b,Pde4b,Malt1,Gsdmd,Fos,Abr,Acsl1,Adgrl2,Cd38,Kremen1,Il4ra,Lyn,Clcf1,Ahr,Htr2b,Ptch1,Irf8,Axl,Hhex,Dhx58,Pik3r6,Fam20c |
| 3.776e-36 | -81.56 | cellular response to cytokine stimulus | biological process | GO:0071345 | 865 | 167 | 20694 | 1406 |
H2-Ab1,Cdc42ep2,Csf3,Stat3,Ifi203,Stat2,Snx10,Jarid2,Casp1,Gbp3,Nmi,Hcls1,Il18rap,Stx11,Ebi3,Pdgfb,Cxcl9,Traf2,Cxcl10,Ifna5,Ifi208,Lrch1,Ifna4,Irgm2,Nos2,Gbp4,Ifi211,Cd300lf,Irak2,Ifi47,Tnfrsf1b,Zc3h12a,Il18,Pid1,Gm4841,Mndal,Flnb,Crkl,Jak2,Stat1,Irf7,Cxcl3,Il12rb1,Tlr2,Gbp2,Evl,Nfkbia,Pf4,Cdc42ep4,Ccl2,Irf1,Stip1,Cx3cr1,Birc3,Ifit3,Gm4951,Vegfc,Eef1e1,Gbp7,Iigp1,Ifna2,Socs3,Egln3,Stat5a,Cxcl1,Socs1,Aim2,Ccl7,Pnpt1,Gclm,Irak3,Myc,Ccl8,Gm12185,Zfp36,Ccl9,Kdm5b,Tgtp2,Ccr3,Pde1b,Tgtp1,Ccrl2,Csf3r,Birc2,Spry2,Serpine1,Igtp,Csf1,H2-Q7,Il15,Fas,Nrp2,Plscr1,Tank,Stoml1,Nfil3,Il6,Klf6,9930111J21Rik1,Ifit1,Dusp1,Gbp2b,Acsl1,Ifit2,Il2rg,Saa3,Lox,Ifi213,Ccl22,Etv3,Ifna1,Sirt1,Il15ra,Axl,Irf8,Il1b,Ifi205,Hk2,Acod1,Ifnar1,Nfkb1,Osm,Il4ra,Ifi209,Cxcl11,Keap1,Ifna6,Gpr35,Irgm1,Rab20,Myd88,Zyx,Ifi207,Ccr1,Pml,Ccl12,Asah2,Stat4,Syk,Cacybp,Ccl4,Stxbp1,Gm5431,Gbp9,Tnf,Cx3cl1,Il1a,Ifi204,Ccl3,Ifitm1,Oas2,Ifi214,Arid5b,Cd74,Il1rn,Il12b,Il13ra1,Gbp8,F830016B08Rik,Stxbp3,Eno1,Srm,Ifnb1,Cxcl2,Egr1,Ccl5,Icam1 |
| 7.579e-36 | -80.87 | GO_INFLAMMATORY_RESPONSE | MSigDB lists | GO_INFLAMMATORY_RESPONSE | 423 | 119 | 15632 | 1249 |
Gsdmd,Aoah,Ass1,Syk,Nlrc4,Fas,Sdc1,Fpr2,Ifi214,Cx3cl1,Il27,Il15,Ifi207,Olr1,S100a8,Ikbkg,Tnfrsf1b,Nfkb1,Rel,Mndal,Ifi211,Csf1,Il18rap,Tlr9,C3,Ifi204,Tnip3,Mmp25,Lyn,Ccl4,Tnf,Tpst1,Bcl6,Ifi209,Stat3,Sele,Gpr68,Prdx5,Aim2,Nupr1,F11r,Myd88,Cd14,Ccl3,Tnfaip3,H2-Eb1,Ccr1,Ccl5,Gja1,Cxcl2,Tlr3,Hp,Hmox1,Ripk2,Il18,Vcam1,Cxcl1,Irak2,Nfkb2,Ptges,Il1b,Ccl12,Fos,Irgm2,Ccr3,Ccl2,Il6,Nfkbiz,Mapkapk2,Tlr6,Ccl22,Il4ra,Nlrp3,Tnfrsf14,Itgal,Il10,Casp4,Plscr1,Ccrl2,Ifi203,Rasgrp1,Tnfsf4,Nox1,Mefv,Pik3cd,Tlr2,Tnip1,Xcr1,Axl,Ifi213,Cd40,Ifi205,Ly75,Acvr1,Hif1a,Icam1,Il1a,Cd180,Sphk1,Nod1,Tnfrsf8,Bmp2,Notch1,Relb,Hck,Slc7a2,Ifi208,Nmi,Tlr1,Nfkbid,Adora2a,Kdm6b,Zc3h12a,Ptgs2,Ptafr,Cxcl10,Il1rn,Thbs1,Pf4 |
| 9.117e-36 | -80.68 | inflammatory response | biological process | GO:0006954 | 445 | 113 | 20694 | 1406 |
Sele,Nlrp3,Notch1,Irak2,Il18,Tnfrsf1b,Zc3h12a,Cxcl3,Tnfaip3,Themis2,Hmox1,Tlr2,Sphk1,Nlrc4,Tlr6,Jak2,Timp1,Casp1,Fpr2,Il18rap,Casp4,Smpdl3b,Stat3,Hck,Nos2,Cxcl9,Ptafr,Cxcl10,Ccr3,Ptgir,Ccl9,Ccl8,Nfkbid,Nod2,Pla2g7,Nupr1,Csf1,Ccrl2,Il10,Cx3cr1,S100a8,Tnfsf4,Acvr1,Tlr9,Pf4,Slamf8,Fcgr1,Ccl2,Cxcl1,Adora2a,Ccl7,Aim2,Ptger4,Cmklr1,Mapkapk2,Axl,Hp,Il1b,Ccl22,Slc7a2,Il4ra,Relb,Tnip1,Lyn,Sdc1,Cxcl11,Tlr3,Nfkbiz,Acod1,Gja1,Itgav,Rel,Bmp2,Pik3cd,Thbs1,Plscr1,Trem1,Olr1,Ciita,Saa3,Ptgs2,Il6,Hif1a,Cd180,C3,Mefv,Tlr1,Kdm6b,Il1rn,Mmp25,Bcl6,Fpr1,Cd14,Gsdmd,Notch2,Icam1,Cxcl2,Serpinb9,Ccl5,Cd40,Ccr1,Nampt,Ccl12,Rasgrp1,Il27,Myd88,Jun,Il1a,Ccl3,Tnf,Cx3cl1,Syk,Ccl4 |
| 9.427e-36 | -80.65 | GSE27434_WT_VS_DNMT1_KO_TREG_DN | MSigDB lists | GSE27434_WT_VS_DNMT1_KO_TREG_DN | 184 | 76 | 15632 | 1249 |
Zfp36,Procr,Kctd12,Birc3,Casp4,Il10,Tnfaip2,Tax1bp1,Jak2,Cdkn1a,Socs3,Mtdh,Map2k4,Lpar1,Irf1,Dusp2,Ccl2,Myc,Peli1,Ifrd1,Sqstm1,Gadd45b,Nfkbia,Nr4a1,Ets2,Dnaja1,Fos,Clec4e,Egr1,Nfkbiz,Il4ra,Pgm1,Prnp,Phlda1,Btg2,Cxcl2,Mmp13,Inhba,Csrp1,Gja1,Junb,Serpine1,Lcp2,Cd86,Ppp1r15a,Serpinb2,Cxcl1,Il1rn,Il1b,Plaur,Crkl,Clec4d,Map3k8,Pim1,Ptgs2,Egr2,Rhoq,Stk40,Errfi1,Mdm2,Txnrd1,Dusp1,Tnf,Ehd1,Tank,Cd14,Cd83,Relb,Mcoln2,Nupr1,Marcksl1,Slc30a4,Prdm1,Ier2,Il1a,Icam1 |
| 1.480e-35 | -80.20 | GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP | MSigDB lists | GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP | 185 | 76 | 15632 | 1249 |
Socs3,Stat1,Pim2,Ifi35,Ebi3,Ms4a6d,Kdr,Fscn1,Clcf1,Pmepa1,Ppfibp2,Nfkb1,Lnpep,Heatr6,Isg20,Akt3,Ksr1,Xaf1,Rictor,Ccrl2,Rtp4,Pikfyve,Phip,Rras2,Tap1,Rnf114,Gadd45b,Nfkbia,Tmem184b,Jun,Gpr18,Znfx1,Bbx,Peli1,Il6,Parp14,Irgm2,Tor1aip2,Ctsc,Slfn8,Parp9,Optn,Zc3h12a,Cxcl10,Slc43a3,Slfn9,Cmpk2,Trafd1,Ccl5,Nampt,Slc4a7,Irf7,Ppm1k,Lgals9,Tlr1,Icosl,Parp12,Car13,Pml,Dtx3l,Sell,Gbp3,Zfp281,Ddx58,Batf,Mcmbp,Ifit2,Gpsm2,Psmb9,Swap70,Gbp9,Ubtd2,Gbp4,Fut8,Rsad2,Dhx58 |
| 1.758e-35 | -80.03 | GO_RESPONSE_TO_BACTERIUM | MSigDB lists | GO_RESPONSE_TO_BACTERIUM | 439 | 121 | 15632 | 1249 |
Irf8,Il10,P2ry2,Trem1,Gfi1,Tlr2,Tnfsf4,Socs3,Nod2,Il18bp,Edn1,Il6,Peli1,Prkce,Fos,Jun,H2-Q4,Cx3cr1,Nfkbia,Ccl12,Tnfrsf14,Plau,Nlrp3,Abr,Mapkapk2,Tlr6,Csf3,Tlr1,Cnp,Cd86,Junb,Gch1,Gng12,Cmpk2,Pf4,Ptgs2,Serpinb9,Ptafr,Cxcl10,Il12b,Clec4d,Ptger4,Zc3h12a,Casp3,Gbp4,Cd40,Axl,Src,Ifnar1,Casp1,Notch1,Hck,Nod1,Tnfrsf8,Cd180,Icam1,Hif1a,Isg15,Socs1,Fgr,Nfkbil1,H2-Q7,Malt1,Nfkbib,Slpi,Cav1,Nos2,Casp8,S100a8,Tnfrsf1b,Nfkb1,Ednrb,Jak2,Tnip3,Trib1,Lyn,Tlr9,Mtdh,Ptgir,Optn,Ifnb1,Pla2g4a,Stap1,Nlrc4,Plac8,Spn,Eif2ak2,Ass1,Syk,Il27,Clec4e,Cd80,Tspo,Nr1h3,Fas,Cxcl2,Fzd5,Serpine1,Pde4b,H2-Eb1,Ccl5,Il1b,Ptges,Vcam1,Cxcl1,Nfkb2,Irak2,Il18,Tlr3,Hp,Ripk2,Sele,Gbp9,Tnfsf8,H2-Q6,Ankrd17,Tnf,Irak3,Tnfaip3,Myd88,Cd14 |
| 2.515e-35 | -79.67 | GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN | 191 | 77 | 15632 | 1249 |
Tapbp,Rsad2,Ccng2,1110038F14Rik,Ly75,Dbnl,Pnp2,Psmb9,Itpr1,Klf6,Ifit2,Ifit1,Daxx,Gbp2,Myd88,Usp18,Tab2,Icam1,Atp11a,Isg15,Psmb10,Ifih1,Gbp3,Pml,Wars,G3bp2,Mmp13,Uba7,Nmi,Irf7,Snx10,Nampt,Cmpk2,Trafd1,Gtpbp2,Kitl,Nfkb2,Clic4,Tmem229b,Cxcl10,Rnf19b,Slc31a1,Ifrd1,Gadd45g,Irgm2,Tor1aip2,Pla2g4a,Ccl2,Znfx1,Jun,Eif2ak2,Mark2,Samhd1,Tap1,Fcgr1,Nck1,Isg20,Procr,Ubr4,Irf8,Ifit3,Gbp7,Casp4,Lcn2,Ogfr,Hdc,Birc3,Psmb8,Ltbp2,Znrf1,Irf1,Gpd2,Lyn,Ifit3b,Ppa1,Stat1,Il13ra1 |
| 5.606e-35 | -78.87 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_DN | 188 | 76 | 15632 | 1249 |
Ap3m2,Rab20,Rcsd1,Ifi35,Cd200,Stat4,Procr,Psme2,Il10,Mov10,S100a8,Tnfrsf14,Chmp4b,Dusp14,Ccnd2,P2ry14,Usp25,Il18bp,Parp9,Parp14,Aftph,Prkce,Ccl2,Tiparp,Spsb1,Plac8,Morc3,Agrn,Epsti1,Glrx,Ptges,Trafd1,Mitd1,Bambi,Cox18,Cxcl10,Il12b,Serpinb9,Tbc1d13,Dgka,Cxcl2,Uba7,Sap30,Trim26,Stxbp3,Tlr1,Cd274,Asah2,Cd86,Nampt,Ccl5,Prpf38a,Hck,Rhoc,Myd88,Gnb4,Atp11a,Tab2,Socs1,Slco3a1,Psme1,Magohb,Irf2,Itga4,Pml,Ogfrl1,Tapbp,Dhx58,1110038F14Rik,Dbnl,Pnp2,Gbp4,Gbp9,Csf3r,Klf6,Spryd7 |
| 6.045e-35 | -78.79 | STK33_UP | MSigDB lists | STK33_UP | 260 | 90 | 15632 | 1249 |
Rhoc,Il1a,Icam1,Dusp8,Egr2,Bcl2a1d,Acvr1,Dusp1,Ifi213,Ifi205,Otud1,Nfxl1,Bcl2a1a,Tfec,Dusp5,Fndc3a,Rnf19b,Tnfsf15,Tlr1,Ifi208,Phlda1,Btg2,Maff,Junb,Nampt,Daam1,Gng11,Plau,Rnd3,Tlr6,Egr1,Nkiras1,Peli1,Kcnj2,Samd9l,Slc7a11,Jun,Dock4,Fos,Fam20c,Rgs1,Trem1,Ifi203,Rnf19a,Csrnp1,Kmo,Upp1,Itgb8,Fgl2,Usp53,Tnf,Klf6,Bcl6,Ifi209,Kitl,Cxcl1,Il1b,Rtn1,Hmox1,Arid5b,Fcho2,Arl5b,AA467197,Cxcl2,Gdf15,Gja1,Ppp1r15a,Olr1,Spred1,Ifi207,Ifi214,P2ry14,Rin2,Sqstm1,Bcl2a1b,Nlrc4,Gbp2b,Ccl4,Gfpt1,Lrrc25,Cdkn1a,Egr3,Cpeb4,Trib1,Ifi204,Zfp36,Ifi211,Stx6,Mndal,Pid1 |
| 1.079e-34 | -78.21 | regulation of programmed cell death | biological process | GO:0043067 | 1540 | 237 | 20694 | 1406 |
Traf2,Mul1,Ripk2,Stk40,Clec5a,Asns,Map4k4,Casp4,Casp1,Uaca,Pim1,Hmox1,Zc3h12a,Il18,Irak2,Notch1,Prokr1,Trip10,Usp42,Adora2a,Tspo,Egln3,Phlpp1,Hdac1,Plaur,Acvr1,Nr4a1,Map2k4,Tnfsf4,Cx3cr1,S100a8,Il10,Serpinb2,Edn1,Dnaja1,Sp110,Lrp8,Fas,Serpine1,Nfkbid,Nod2,Zfp36,Gclm,Irak3,Itga4,Gadd45g,Sav1,Sgk3,Higd1a,Atm,Nes,Ptgs2,Traf1,Bcl2a1d,Ifit2,Hspa1b,Plscr1,Hsph1,Rapgef2,Fam72a,Pik3cd,Cd38,Tax1bp1,Htr2b,Itpr1,Clcf1,Cav1,Lyn,Sell,Chst11,Osm,Slc7a11,Ier3,Sirt1,Mmp9,Arel1,Arf4,Cd274,Grina,Acsl5,Axl,Stxbp1,Syk,Cited2,Tnf,Plk3,Daxx,Ccl3,Jun,Sod2,Fam162a,Nsmaf,Angpt1,Bfar,Eya4,Ccl12,Asah2,Pim2,Atf3,Ciapin1,Pml,Phip,Nox1,Mtdh,Cd40,Igf1r,Serpinb9,Ccl5,Hk1,Icam1,Ifnb1,Nod1,Cdkn2d,Irs2,Malt1,Nqo1,Rnf31,Insl6,Gclc,Cd74,Cxcl10,Arg2,Klrk1,Lpar1,Tnfsf15,Egr3,Peli1,Bcl2a1a,Phlda1,Src,Hck,Stat3,Bcl2l11,Nr3c1,Hcls1,Map2k1,Prdx5,Jak2,Timp1,Stat1,Nlrc4,Sphk1,Adar,Traf5,Ripk3,Tnfaip3,Inhba,Cycs,Tnfrsf1b,Hk3,Plac8,Optn,Nlrp3,Plekhn1,Rnf34,Socs3,Ppp2r1b,Mecp2,Eef1e1,Dcun1d3,Pdpn,Eif2ak2,Stat5a,Slc9a1,Pf4,Apaf1,Adrb2,Glrx,Birc3,Birc2,Nupr1,Hcar2,Spry2,Col18a1,Ptpn2,Plagl2,Pdgfrb,Myc,Pde5a,Ptk2,Ccnd2,Dusp1,Hif1a,Itga5,Il6,Tnfrsf8,Lox,Cflar,Prnp,Plk2,Cpeb4,Thbs1,Mt1,Bmp2,Ctsc,Casp2,Casp3,Gja1,Itgav,Ikbkg,Tnfsf14,Psmd10,Prkce,Cdk5r1,Nr4a3,Nfkb1,4930453N24Rik,Mdm2,Btg2,Il1b,Pim3,Pmaip1,Dusp6,Kdr,Bcl2a1b,Cx3cl1,Rffl,Kitl,Met,Tnfsf10,Nck1,Ift57,Pla2g4a,Fcgr2b,Cdkn1a,Casp8,Egr1,Rgcc,Notch2,Ednrb,Bnip3,Bcl6,Gdf15,Il1rn,Il12b,Agrn,Gadd45b |
| 1.254e-34 | -78.06 | regulation of cell communication | biological process | GO:0010646 | 3321 | 401 | 20694 | 1406 |
Irf1,Phlpp1,Map2k4,Intu,Il10,Cx3cr1,Bst1,Cmklr1,Plpp3,Rab11fip1,Irf4,Gclm,Ptgir,Mmp14,Ddx60,Sgk3,Sema4c,Cish,Edn1,Dnaja1,Prkar2b,Stau1,Socs7,Fas,Nfkbil1,Casp4,Rrs1,Casp1,Hap1,Ifna5,Traf2,Wdfy1,Rnf14,Rhbdf2,Stk40,Mul1,Ripk2,Tifa,Lrp4,Il18,Zc3h12a,Gfi1,Marco,Gpr18,Angpt1,Prdx1,Asah2,Acpp,Ccl12,Rasgrp1,Atf3,Bambi,Stxbp1,Cited2,Daxx,Il1a,Mapkbp1,Tnf,Rsad2,Tcf4,Jun,Fam162a,Aida,Rpgrip1l,Gclc,Cd180,Pfkl,Cd40,Psd,Nlgn2,Mtdh,Icam1,Irs2,Slc16a1,Uchl1,Plscr1,Dusp5,Hsph1,Rapgef2,Adora2b,F10,Cyfip1,Ptgs2,Traf1,Ksr1,Mmp9,Sirt1,Ccl22,Plcl2,Kctd12,Lgals9,Itpr1,Acod1,Sqstm1,Myadm,Trim30a,Osm,Cav1,Klf7,Ccl2,Adrb2,Nfkbia,Slc30a1,Birc3,Ifna2,Socs3,Rbpms,Rnf34,Eef1e1,Eif2ak2,Socs1,Map3k8,Fzd5,Ptpn2,Pdgfrb,Ccl8,Tle3,Nr1h3,Kdm5b,Prag1,Ptk2,Sipa1l1,S1pr2,Hcar2,Il15,Nupr1,Csf1,Mob3b,Bcl2a1a,Bcl2l11,Peli1,Nr3c1,Treml4,Map2k1,Fpr2,Flt1,Usp12,Lif,Gpc1,Tnfsf15,Clec4n,Scimp,Nlrp3,Rgs14,Akt3,Zc3hav1,Errfi1,Tlr6,Jak2,Timp1,Zbp1,Sphk1,Rap1gap2,Vasn,Hmgn3,Traf5,Rictor,Irf7,Tnfaip3,Inhba,Tnfsf10,Acvrl1,Gpr35,Rnf19a,Nck1,Ifna6,Spata13,Casp8,Bcl2a1b,Sik3,Dusp6,P2ry2,Arhgap26,P2ry12,Rffl,Cd14,Bnip3,Traf3ip2,Il12b,Mosmo,Tnip3,Srgn,Plek,Bmp2,Casp2,Dusp1,Acvr1b,Lox,Mid1,Ifna1,Mlkl,Sla,Pim3,Il1b,Pmaip1,Trib3,Tlr3,Plat,Cdk5r1,Prkce,Nfkb1,Plau,Hdac1,Tnfsf4,Acvr1,Plaur,S100a8,Ptger4,Atp2b4,Adora2a,Gadd45g,Irak3,Nectin2,Homer1,Stap1,Tsku,Lrp8,Nfkbid,Nod2,Serpine1,Dyrk2,Gcnt2,Csf3,Map4k4,Ptprj,Htra1,Spred1,Tab2,Nos2,Wdr59,Sesn3,Ifna4,Irgm2,Parp9,Cyth3,Itgal,Cd300lf,Irak2,Notch1,Rhoh,Rgs1,Pid1,Uaca,Hmox1,Tlr2,Prdm1,Bfar,Pik3r5,Pim2,Eya4,Ago3,Ccr1,Pml,Ccl4,Syk,Pde3b,Sh3bp4,Ccl3,Fzd1,Sod2,Malt1,Rnf31,Pde4b,Tlr1,Cd74,C3,Phip,Nox1,Igf1r,Map3k6,Ankrd17,Fgr,Vrk2,Rabgef1,Ccl5,Cdkn2d,Ifnb1,Nod1,Tank,Fam72a,Cd38,Rgs3,Dusp2,Arhgef3,Higd1a,Atm,Bcl2a1d,Abr,Ier3,Fam20c,Hhex,Dhx58,Pik3r6,Axl,Acsl5,Trim13,Grina,Rims3,Ptch1,Htr2b,Clcf1,Kremen1,Tnip1,Slc7a11,Lyn,Chst11,Ppfia3,Pf4,Apaf1,Tlr9,Slc9a1,Glrx,Scyl2,Ddit4,Ezr,Parp14,Cenpj,Znrf3,Tulp3,Phactr4,Vegfc,Mecp2,Ppp2r1b,Ccl7,Card6,Glipr2,Plagl2,Htr2a,Myc,Pde5a,Zeb1,Ccl9,Kmo,Birc2,Dusp16,Ntng2,Spry2,Src,Stat3,Gpr68,Smpdl3b,Hcls1,Pdgfb,Ikbke,Lpar1,Apba1,Optn,Stat1,Crkl,Cysltr2,Ripk3,Adar,Trib1,Ncoa5,Met,Myd88,Serp1,Irgm1,Fcgr2b,Kdr,Ubash3b,Nlrc5,Mdfic,Cx3cl1,Cacna1d,Kitl,Dusp4,Gdf15,Bcl6,Spred3,Gadd45b,Cgas,Il1rn,Rcan1,Kmt5a,Egr1,Pmepa1,Notch2,Prnp,Cacnb3,Grk3,Plk2,Thbs1,Ctsc,Samhd1,Hif1a,Il6,Jag1,Dusp8,Cflar,Pdgfc,Mdm2,Ppp2r3a,Hmga2,Ikbkg,Gja1,Itgav,Psmd10,Tnfsf14,Crlf3,Psd4 |
| 1.391e-34 | -77.96 | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP | 171 | 72 | 15632 | 1249 |
Tnfaip3,Sla,Myd88,Rnd1,Tab2,Mcoln2,Parp10,Marcksl1,Mxd1,Psma6,Itgb8,Serp1,N4bp1,Plekhf2,Ehd1,Stat5a,Lacc1,Ikbke,Clic4,Thbs1,Cmklr1,Ptafr,Map3k8,Il12b,Kcna3,Grina,Ptprj,Rnf19b,Stx11,Vasp,Csf3,Slc2a6,Gpr132,Samsn1,Gch1,Pde4b,Zc3hav1,Klf7,Clec4e,Cdc42ep2,Pfkfb3,Nlrp3,Tmtc2,Fpr2,Dcp2,Nfkbiz,Rin2,Tgs1,Il4i1,Kcnj2,Dnaja1,Trip10,Pik3r5,Cnn2,Plac8,Gramd1a,Tnip1,Rap2c,Tmem123,Tnfaip2,Fscn1,Acsl1,Tnip3,Irf1,Oasl1,Ebi3,Rhou,Tifa,Atxn7l1,Pstpip2,Dcun1d3,Birc3 |
| 1.580e-34 | -77.83 | regulation of signaling | biological process | GO:0023051 | 3336 | 402 | 20694 | 1406 |
Kmo,Ccl9,Zeb1,Plagl2,Pde5a,Myc,Htr2a,Spry2,Ntng2,Dusp16,Birc2,Ddit4,Scyl2,Glrx,Ezr,Parp14,Ppfia3,Slc9a1,Pf4,Apaf1,Tlr9,Card6,Ccl7,Glipr2,Znrf3,Cenpj,Mecp2,Ppp2r1b,Phactr4,Tulp3,Vegfc,Apba1,Optn,Adar,Ripk3,Cysltr2,Ncoa5,Trib1,Stat1,Crkl,Hcls1,Stat3,Src,Smpdl3b,Gpr68,Ikbke,Lpar1,Pdgfb,Cgas,Il1rn,Gadd45b,Spred3,Rcan1,Bcl6,Gdf15,Dusp4,Pmepa1,Egr1,Notch2,Kmt5a,Fcgr2b,Irgm1,Serp1,Myd88,Met,Cx3cl1,Mdfic,Kitl,Cacna1d,Kdr,Nlrc5,Ubash3b,Ppp2r3a,Hmga2,Pdgfc,Mdm2,Tnfsf14,Psmd10,Psd4,Crlf3,Gja1,Itgav,Ikbkg,Samhd1,Ctsc,Prnp,Thbs1,Plk2,Grk3,Cacnb3,Dusp8,Jag1,Cflar,Hif1a,Il6,Nectin2,Irak3,Gadd45g,Lrp8,Serpine1,Nod2,Nfkbid,Tsku,Stap1,Homer1,Acvr1,Plaur,Tnfsf4,S100a8,Plau,Hdac1,Adora2a,Atp2b4,Ptger4,Rhoh,Notch1,Pid1,Rgs1,Itgal,Cd300lf,Irak2,Tlr2,Hmox1,Uaca,Ptprj,Csf3,Gcnt2,Dyrk2,Map4k4,Wdr59,Nos2,Tab2,Cyth3,Parp9,Irgm2,Ifna4,Sesn3,Htra1,Spred1,Tlr1,C3,Cd74,Malt1,Rnf31,Pde4b,Ccl5,Rabgef1,Ifnb1,Nod1,Cdkn2d,Phip,Nox1,Fgr,Vrk2,Map3k6,Ankrd17,Igf1r,Ago3,Eya4,Pim2,Pml,Ccr1,Pik3r5,Bfar,Prdm1,Ccl3,Sod2,Fzd1,Ccl4,Sh3bp4,Pde3b,Syk,Pik3r6,Dhx58,Hhex,Grina,Trim13,Axl,Acsl5,Ier3,Fam20c,Clcf1,Chst11,Lyn,Slc7a11,Tnip1,Kremen1,Ptch1,Htr2b,Rims3,Dusp2,Rgs3,Arhgef3,Tank,Cd38,Fam72a,Abr,Bcl2a1d,Higd1a,Atm,Prag1,Kdm5b,Nr1h3,Tle3,Ptk2,Pdgfrb,Fzd5,Ptpn2,Ccl8,Csf1,Nupr1,Hcar2,Il15,Mob3b,Sipa1l1,S1pr2,Birc3,Ccl2,Slc30a1,Adrb2,Nfkbia,Socs1,Eif2ak2,Map3k8,Rnf34,Rbpms,Socs3,Ifna2,Eef1e1,Nlrp3,Scimp,Zc3hav1,Rgs14,Akt3,Clec4n,Hmgn3,Traf5,Vasn,Inhba,Tnfaip3,Irf7,Rictor,Timp1,Jak2,Tlr6,Errfi1,Rap1gap2,Zbp1,Sphk1,Map2k1,Fpr2,Peli1,Bcl2l11,Bcl2a1a,Treml4,Nr3c1,Gpc1,Tnfsf15,Usp12,Flt1,Lif,Il12b,Traf3ip2,Cd14,Bnip3,Srgn,Tnip3,Mosmo,Spata13,Casp8,Acvrl1,Gpr35,Tnfsf10,Ifna6,Nck1,Rnf19a,P2ry2,Rffl,P2ry12,Arhgap26,Dusp6,Sik3,Bcl2a1b,Il1b,Pim3,Sla,Trib3,Pmaip1,Ifna1,Mlkl,Prkce,Cdk5r1,Nfkb1,Plat,Tlr3,Bmp2,Casp2,Plek,Mid1,Lox,Acvr1b,Dusp1,Ptgir,Sgk3,Ddx60,Mmp14,Irf4,Gclm,Fas,Edn1,Sema4c,Cish,Socs7,Stau1,Prkar2b,Dnaja1,Intu,Map2k4,Cx3cr1,Il10,Irf1,Phlpp1,Rab11fip1,Cmklr1,Bst1,Plpp3,Gfi1,Zc3h12a,Il18,Gpr18,Marco,Rrs1,Hap1,Casp1,Casp4,Nfkbil1,Rhbdf2,Rnf14,Mvp,Wdfy1,Tifa,Lrp4,Mul1,Ripk2,Stk40,Traf2,Ifna5,Gclc,Cd180,Rpgrip1l,Aida,Icam1,Uchl1,Slc16a1,Irs2,Mtdh,Nlgn2,Cd40,Pfkl,Psd,Rasgrp1,Ccl12,Acpp,Asah2,Atf3,Angpt1,Prdx1,Tnf,Mapkbp1,Il1a,Daxx,Fam162a,Tcf4,Jun,Rsad2,Stxbp1,Bambi,Cited2,Kctd12,Lgals9,Mmp9,Sirt1,Ccl22,Plcl2,Trim30a,Myadm,Klf7,Cav1,Osm,Acod1,Itpr1,Sqstm1,F10,Adora2b,Dusp5,Plscr1,Hsph1,Rapgef2,Ptgs2,Ksr1,Traf1,Cyfip1 |
| 2.266e-34 | -77.47 | GO_CELLULAR_RESPONSE_TO_ORGANIC_SUBSTANCE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ORGANIC_SUBSTANCE | 1722 | 281 | 15632 | 1249 |
Ifnb1,Stap1,Dnaja1,Syk,Ass1,Eif2ak2,Nr4a1,Slc16a1,Il15,Mul1,Irs2,Nfkbib,Med13,Psme2,Csf1,Slc9a1,Trim21,Casp8,Plod2,Nfkb1,Pmepa1,Nfil3,Ccl4,Polr2g,Jak2,Lyn,Ptk2,Max,Rsad2,Errfi1,Gbp9,Tnc,Serp1,P2ry13,H2-Q6,Traf2,Klf6,Tnf,Tnfaip3,Cd14,Cd74,Cxcl2,Fzd1,Inhba,Il12rb1,Sh3bp4,Rapgef2,Nrp2,Trim26,Rab10,Atp6v1d,Fosb,Flrt2,Asns,Ppp1r15a,Ccl5,Gdf15,Pde4b,Irak2,Vcam1,Il2rg,Trib3,Tlr3,Il18bp,Ccl2,Il6,Ccr3,Jun,Tiparp,Msr1,Ccl12,Nfkbia,H2-Q4,Cx3cr1,Samhd1,Pde3b,Plau,Ifna1,Il4ra,Ccl22,Etv3,Phip,Lrp8,Mapkapk2,Ccrl2,P2ry2,Il10,Tnfsf14,Pdk3,Prkar2b,Igf1r,Hcls1,Kdr,Tlr2,Acsl1,Irf1,Il13ra1,Socs3,Ebi3,Tnfsf4,Acvrl1,Acvr1,Rhoq,Pde1b,Nr3c1,Psmb9,Casp1,Ifnar1,Lrp4,Dusp1,Axl,Daxx,Bmp2,Nod1,Sphk1,Icam1,Pml,H2-Q7,Psme1,Nfkbil1,Hap1,Tyk2,Tnfsf15,Cd86,Junb,Ifit1bl2,Cmpk2,Il15ra,Il12b,Pim1,Ptgs2,Mid1,Ifna5,Ptpn2,Klf3,Zc3hav1,Ahr,Spred1,Tspo,Cd80,Col4a2,Nr1h3,Cx3cl1,Kat2b,Fas,Il18rap,Xaf1,Zeb1,Isg20,Nos2,Pid1,Cav1,Ednrb,Tnfrsf1b,Rnf14,Gfpt1,Ifit3b,Lpar1,Tnip3,Oasl1,Egr3,Mtdh,Cpeb4,Hmgcs1,Stat3,Oas3,Csf3r,Plod3,Ifit2,Stat5a,Ccl3,Ifna2,Irak3,Pdgfc,Apaf1,Gnb4,Psmb10,F11r,Aim2,H2-Aa,Ddit4,Pdgfrb,Irf7,Osm,Serpine1,Ccr1,H2-Eb1,Il1b,Keap1,Htr2b,Gcnt2,Cxcl1,Nr4a3,Il18,Ripk2,Gng4,Psmb6,Nod2,Prkce,Irf4,Edn1,Zyx,Fos,Psmd10,Flrt3,Flt1,Ezr,Ifit1bl1,Atp2b4,Tnfrsf14,Gng11,Pnpt1,Adar,Fcgr1,Ciita,Nlrp3,Egr1,Atf3,Oas1a,Sirt1,Ptch1,Casp4,Irf8,Ifit3,Ltbp2,Ccne1,Psmb8,Birc3,Socs7,Gfi1,Xcr1,Clcf1,Stat1,Ifi35,Psma6,Kdm5b,Ccnd1,Mdm2,Cish,Gbp4,Egr2,Casp3,Fut8,Cd40,Birc2,P2ry12,Ehd1,Src,Gbp2,Hck,Notch1,Tnfrsf8,Trim12c,Socs1,Agtrap,Isg15,St3gal6,Il1a,Cd180,Hif1a,Calcrl,Stat2,Irf2,Itga4,Oas2,Csf3,Ifna6,Pdgfb,Klf2,Nampt,Pf4,Gng12,Bambi,Cmklr1,Cxcl10,Ptafr,Serpinb9,Zc3h12a,Oas1g,Ptger4,H2-Ab1 |
| 2.320e-34 | -77.45 | positive regulation of cytokine production | biological process | GO:0001819 | 438 | 110 | 20694 | 1406 |
Clec4e,Cd200,Ddx58,Tlr2,Irf7,Tarm1,Il12rb1,Tlr6,Jak2,Stat1,Sphk1,Mndal,Nlrp3,Zc3hav1,Il18,Ifi211,Clec4n,Optn,Ripk2,Tnfsf15,Traf2,Ptafr,Klrk1,Ptprj,Casp1,Clec5a,Peli1,Src,Icosl,Stat3,Casp4,Il15,Serpine1,Nod2,Ifih1,Ddx60,Fzd5,Irf4,Aim2,Eif2ak2,Stat5a,Mcoln2,Ptger4,Tnfsf4,Il10,Ccl2,Irf1,Hdac1,Pf4,Tlr9,Nr4a3,Tnfrsf14,Osm,Il4ra,Htr2b,Ifnar1,Ifi205,Tlr3,Dhx58,Il1b,Cd274,Cd83,Lgals9,Mapkapk2,Irf8,Tnfrsf8,Ptgs2,Hif1a,Hilpda,Il6,Adora2b,Rel,Tnfsf9,Thbs1,Spn,Cd34,Egr1,Ccl5,Hk1,Rgcc,Nod1,Ankrd17,Fgr,Cd40,Il1rn,Cgas,Il12b,Tlr1,Ccdc88b,Cd74,C3,Gsdmd,Malt1,Cd14,Pde4b,Tnf,Cx3cl1,Ifi204,Il1a,Ccl3,P2ry2,Rsad2,Ccl4,Rnf135,Syk,Rasgrp1,Arid5a,Casp8,Myd88,Il27 |
| 3.447e-34 | -77.05 | GO_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | MSigDB lists | GO_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | 293 | 95 | 15632 | 1249 |
Irak3,Tnfaip3,Cd14,Tnf,Sele,Il18,Ripk2,Ptges,Il1b,Nfkb2,Irak2,Cxcl1,Vcam1,Serpine1,Fzd5,Ccl5,Pde4b,Cxcl2,Nr1h3,Fas,Cd80,Tspo,Ass1,Eif2ak2,Stap1,Pla2g4a,Lyn,Tnip3,Trib1,Ptgir,Mtdh,Tlr9,Jak2,Nos2,Casp8,Nfkb1,Tnfrsf1b,Ednrb,S100a8,Nfkbib,Slpi,Socs1,Icam1,Hif1a,Cd180,Nfkbil1,Malt1,Hck,Notch1,Tnfrsf8,Cd40,Ifnar1,Casp1,Axl,Src,Casp3,Ptafr,Il12b,Cxcl10,Ptgs2,Zc3h12a,Ptger4,Pf4,Cmpk2,Gng12,Cd86,Cnp,Gch1,Junb,Csf3,Tlr1,Nlrp3,Mapkapk2,Tlr6,Abr,Tnfrsf14,Plau,Jun,Fos,Ccl12,Cx3cr1,Nfkbia,Nod2,Il18bp,Il6,Peli1,Prkce,Edn1,Tlr2,Socs3,Tnfsf4,Gfi1,P2ry2,Il10,Irf8 |
| 3.926e-34 | -76.92 | defense response to virus | biological process | GO:0051607 | 176 | 68 | 20694 | 1406 |
Irf2,Ddit4,Ifit3,Trim56,Pml,Oas3,Irf1,Ifna6,Tlr9,Oasl1,Eif2ak2,Shfl,Rsad2,Trim12a,Slfn9,Apobec3,Ifna2,Cgas,Oas1b,Il12b,Nt5c3,Ddx60,Dtx3l,Bnip3,Ifitm1,Oas2,Tagap,Ifnb1,Ifih1,Cd40,Cd86,Samhd1,Ifit3b,Isg20,Stat2,Plscr1,Treml4,Slfn8,Parp9,Ifna4,Oasl2,Ifit2,Oas1a,Cxcl10,Gbp2b,Ifit1,Ifit1bl1,Il6,Cxcl9,Dhx58,Nlrp3,Isg15,Zc3hav1,Ifna1,Trim34a,Adar,Ddx58,Trim30a,Irf7,Mx2,Oas1g,Rtp4,Stat1,Ifit1bl2,Ifnar1,Mx1,Zbp1,Tlr3 |
| 6.661e-34 | -76.39 | GSE42021_CD24HI_VS_CD24LOW_TREG_THYMUS_DN | MSigDB lists | GSE42021_CD24HI_VS_CD24LOW_TREG_THYMUS_DN | 184 | 74 | 15632 | 1249 |
H2-Q7,Pml,Ddx58,Usp18,Trim12c,Sell,Socs1,Isg15,Ifih1,Myd88,Cd164,Tnfaip3,Ifit2,Phf11b,Ifi213,Stat5a,H2-Q6,Ifi205,Oas3,Ifi209,Ifi44,Mecp2,Tlk2,Rsad2,Rnf19b,Atp10a,Herc6,Tlr3,Oas1g,Cxcl10,Tnfsf10,Sp110,Trafd1,Ifit1bl2,Gch1,Cnp,Irf7,Ext1,Ifi208,Stoml1,Oas2,Parp12,Atf3,Ddx60,Ccl22,Ifi214,Phf11a,Ifi207,Phf11c,Eif2ak2,Ifit1bl1,H2-Q4,Flrt3,Rnf114,Ets2,Tgs1,Phactr4,Ifi35,Casp7,Oasl1,Phf11d,Ifi204,Ifit3b,Ifit3,Mndal,Lap3,Ifi211,Isg20,Trim14,Plscr1,Oas1a,Tdrd7,Ifi203,Xaf1 |
| 9.468e-34 | -76.04 | BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE | MSigDB lists | BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE | 67 | 45 | 15632 | 1249 |
Oas3,Cd40,Rsad2,Dhx58,Ifi44,Gbp3,Ifih1,Stat2,Pml,Itga4,Ncoa7,Nod1,Irf7,Cd274,Gch1,Ifit1bl2,Oas2,Parp12,Trafd1,Epsti1,Tnfsf10,Ptpn2,Ccl12,Eif2ak2,Ifit1bl1,Samd9l,Rin2,P2ry14,Ddx60,Zbp1,Slamf7,Cd80,Pnpt1,Gbp7,Ifit3,Mov10,Tmem176a,Tdrd7,Xaf1,St3gal5,Ifit3b,Ms4a6d,Tnip3,Oasl1,Ifi35 |
| 1.120e-33 | -75.87 | GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 1531 | 258 | 15632 | 1249 |
Abr,Atf3,Nlrp3,Htr2a,Tnfrsf14,Atp2b4,Angpt1,Ezr,Flt1,Map3k6,Bcl2l11,Flrt3,Psmd10,Edn1,Prkce,Taf4b,Nod2,Nox1,Stat1,Dyrk2,Pik3cd,Ier3,Adrb2,Clcf1,Cflar,Tnip1,Tagap,Socs7,Birc3,Rabgef1,Cysltr2,Ksr1,Sirt1,Eef1e1,Rasgrp1,Malt1,Lif,Rhoh,Il1a,Hif1a,Socs1,Trim12c,Crlf3,Notch1,Mdfic,Hsph1,Src,Itpr1,Rgs14,Birc2,Cd40,Rbbp8,Hspa1a,Dusp8,Cish,Mdm2,Stk40,Ptger4,Zc3h12a,Grina,Fpr1,Cxcl10,Cmklr1,Thbs1,Plaur,Pf4,Plk2,Sipa1l1,Wdr59,Inpp5b,Pdgfb,Ifna6,Csf3,Fas,Cdkn2d,Nek6,Cx3cl1,Cdk5r1,Cd80,Spred1,Dusp14,Zc3hav1,Gadd45b,Trip10,Ptpn2,Dusp2,S1pr2,Optn,Gadd45g,Ifna5,Mid1,Tlr9,Mtdh,Ptgir,Mmp9,C3,Uaca,Rac3,Pim2,Tnip3,Lpar1,Notch2,Tnfrsf1b,Cav1,Rel,Plekhg1,Rictor,Rap1gap2,Plk3,Tab2,Myd88,Rnf34,Pdgfc,Irak3,Ifna2,Ccl3,Plagl2,Arhgef3,Ankrd17,Stat3,Glipr2,Hmox1,Ripk2,Adora2b,Map3k8,Il18,Kitl,Ikbke,Gcnt2,Htr2b,Il1b,Ccr1,Gja1,Psd4,Fzd5,Osm,Map2k1,Pdgfrb,Ddit4,Tlr6,Mapkapk2,Trim13,Prnp,Ccl22,Ifna1,Prdx1,Pde3b,Nfkbia,Pik3r5,Ccl12,Rhof,Jun,Spry2,Peli1,Il6,Myc,Ccl2,Socs3,Aida,Tlr2,Hcls1,Kdr,Igf1r,Clec4n,Rnf31,Tnfsf14,Il10,Pml,Spata13,Icam1,Sphk1,Fgr,Nod1,Bmp2,Ripk3,Daxx,Rhoc,Axl,Dusp1,Casp1,Rhoq,Top3a,Rffl,Dbnl,Ptprj,Uchl1,Traf3ip2,Dusp5,Ptgs2,Il12b,Tnfsf10,Txn1,Map4k4,Cd86,Pik3r6,Tnfsf15,G3bp2,Nfkbid,Hap1,Nck1,Ddx60,Cyth3,Irs2,Tpx2,Mul1,F10,Il15,Eif2ak2,Sod2,Sqstm1,Syk,Dnaja1,Phlpp1,Psd,Dusp4,Ifnb1,Pde5a,Sema4c,Ptk2,Trib1,Lyn,Jak2,Ccl4,Dusp16,Vrk2,S100a8,Atm,Ikbkg,Casp8,Slc9a1,Csf1,Nfkbib,Rhou,Cd74,Traf5,Rgs3,Tnfaip3,Tnf,Traf2,Bcl6,Hdac1,Arhgap26,Errfi1,Dhx58,Tlr3,Crkl,Trib3,Rcan1,Irak2,Plek,Gdf15,Ccl5,Dusp6,Myadm,Flrt2,Sh3bp4,Rapgef2,Inhba |
| 1.219e-33 | -75.79 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_UP | 171 | 71 | 15632 | 1249 |
Tnf,Ehd1,Bcl2a1d,Rbpms,Itgb8,Slc15a3,Rab21,Pigv,Traf1,Il1a,Plk3,Irak3,Tnfaip3,Crim1,Batf,Map2k1,Myo1b,Nampt,Txn1,Maff,Cxcl2,Inhba,Slc2a6,Il12b,Ak4,Ptgs2,Slc43a3,Zc3h12a,St3gal1,Il1b,Snn,Plaur,Il15ra,Plat,Bcl2a1a,Cxcl1,Acsl5,Rhof,Trip10,Ets2,Mrpl52,Bcl2a1b,Sod2,Plac8,Flt1,Rin2,Il6,Dusp2,Mmp14,Gmppb,Fpr2,Etv3,Slamf7,Pfkfb3,Il10,Tnfrsf1b,Abtb2,Stat4,Ampd3,Pdss1,Nfkbib,Ier3,Acsl1,Tnip3,Socs3,Ebi3,Agpat4,Rap2c,Ccl4,Tnip1,Cflar |
| 1.483e-33 | -75.59 | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP | 181 | 73 | 15632 | 1249 |
Cflar,Rap2c,Tnip1,Tnip3,Ier3,Lyn,Ebi3,Pim2,Ptgir,Oasl1,Ccrl2,Stat4,Rasgrp1,Dcp1a,Met,Isg20,Med13,Il10,Gna15,Ubr4,Sik3,Abtb2,Pfkfb3,Cdc42ep2,Nxf1,Nlrp3,Dusp4,Stard5,Il6,Ets2,Trim36,Gadd45b,Hivep2,Nfkbia,Plac8,Sod2,Il15ra,Zhx2,Acsl5,Ptgs2,Il12b,Serpinb9,St3gal1,Ripk2,Zc3h12a,Inhba,Slc2a6,Lcp2,Ppp1r15a,Irf7,Nampt,Jarid2,Pde4b,Gch1,Brd2,Ccl5,Tnfaip3,Irak3,Relb,Icam1,Il1a,Upp1,Traf1,Plk3,Lrch3,Hlx,Rhoh,Rsad2,Nr3c1,Slc25a37,Src,Klf6,Ehd1 |
| 1.760e-33 | -75.42 | positive regulation of phosphate metabolic process | biological process | GO:0045937 | 1124 | 191 | 20694 | 1406 |
Crkl,Sphk1,Jak2,Tlr6,Rictor,Pgk1,Inhba,Ripk3,Cysltr2,Scimp,Ranbp2,Lif,Pdgfb,Ptafr,Flt1,Tnfsf15,Lpar1,Tnks1bp1,Stat3,Src,Fpr2,Map2k1,Hcls1,S1pr2,Hspa2,Spry2,Il15,Csf1,Nupr1,Htr2a,Ccl8,Pde5a,Myc,Pdgfrb,Fzd5,Ptk2,Ccl9,Vegfc,Ifna2,Rbpms,Glipr2,Map3k8,Ccl7,Eif2ak2,Adrb2,Tlr9,Fcgr1,Ccl2,Parp14,Tlr3,Ikbkg,Ppp2r5a,Pcx,Tnfrsf14,Psmd10,Prkce,Cdk5r1,Ccnd1,Mlkl,Pdgfc,Ifna1,Il1b,Il6,Acvr1b,Itga5,Ccnd2,Cflar,Mid1,Grk3,Thbs1,Plek,Prnp,Bmp2,Notch2,Rgcc,Egr1,Gdf15,Ednrb,Ppp1r15a,Gadd45b,Il12b,Agrn,Txn1,Il1rn,Kdr,Kitl,Mdfic,Cx3cl1,Ifna6,Myd88,Met,Acvrl1,Cdkn1a,Sdc4,Fcgr2b,Marco,Tlr2,Pim1,Irak2,Il18,Zc3h12a,Pid1,Notch1,Nek6,Ifna5,Traf2,Irgm2,Ifna4,Lrp4,Parp9,Mul1,Ripk2,Tab2,Nos2,Map4k4,Gcnt2,Csf3,Ptprj,Sema4c,Stap1,Edn1,Nod2,Mtcp1,Fas,Lrp8,Gadd45g,Atp2b4,Ptger4,Plpp3,Cenpe,Hdac1,Cx3cr1,Map2k4,Ppp1r15b,Acvr1,Plaur,Sqstm1,Lmo4,Htr2b,Osm,Cav1,Lyn,Clcf1,Ccl22,Sirt1,Mmp9,Lgals9,Pik3r6,Cd80,Atm,Acsl1,Higd1a,Ksr1,Mmd,Ptgs2,Spn,Hsph1,Rapgef2,Fam129a,Adora2b,Rap2c,Igf1r,Cd40,Fgr,Map3k6,Nox1,Phip,Nod1,Ifnb1,Icam1,Ccl5,Malt1,C3,Cd74,Fabp3,Tlr1,Syk,Tpx2,Ccl4,Fzd1,Jun,Ccl3,Il1a,Daxx,Tnf,Mapkbp1,Pik3r5,Angpt1,Ccr1,Rasgrp1,Ccl12 |
| 1.760e-33 | -75.42 | positive regulation of phosphorus metabolic process | biological process | GO:0010562 | 1124 | 191 | 20694 | 1406 |
Lpar1,Tnfsf15,Lif,Pdgfb,Flt1,Ptafr,Fpr2,Hcls1,Map2k1,Tnks1bp1,Stat3,Src,Inhba,Pgk1,Rictor,Ripk3,Cysltr2,Sphk1,Crkl,Jak2,Tlr6,Ranbp2,Scimp,Map3k8,Glipr2,Ccl7,Eif2ak2,Vegfc,Rbpms,Ifna2,Parp14,Fcgr1,Tlr9,Adrb2,Ccl2,Spry2,Nupr1,Csf1,Il15,Hspa2,S1pr2,Ptk2,Ccl9,Ccl8,Myc,Pde5a,Htr2a,Pdgfrb,Fzd5,Cflar,Mid1,Il6,Ccnd2,Itga5,Acvr1b,Bmp2,Thbs1,Grk3,Prnp,Plek,Ppp2r5a,Pcx,Tnfrsf14,Ccnd1,Cdk5r1,Psmd10,Prkce,Tlr3,Ikbkg,Il1b,Mlkl,Pdgfc,Ifna1,Kitl,Cx3cl1,Mdfic,Kdr,Cdkn1a,Sdc4,Fcgr2b,Ifna6,Acvrl1,Myd88,Met,Notch2,Egr1,Rgcc,Il12b,Agrn,Il1rn,Txn1,Gadd45b,Gdf15,Ednrb,Ppp1r15a,Lrp4,Parp9,Mul1,Ripk2,Irgm2,Ifna4,Nos2,Tab2,Nek6,Traf2,Ifna5,Ptprj,Map4k4,Csf3,Gcnt2,Pim1,Tlr2,Marco,Pid1,Notch1,Irak2,Zc3h12a,Il18,Plpp3,Atp2b4,Ptger4,Cenpe,Cx3cr1,Ppp1r15b,Plaur,Acvr1,Map2k4,Hdac1,Nod2,Mtcp1,Lrp8,Fas,Edn1,Stap1,Sema4c,Gadd45g,Mmd,Ksr1,Ptgs2,Atm,Cd80,Higd1a,Acsl1,Adora2b,Rap2c,Hsph1,Rapgef2,Spn,Fam129a,Lyn,Cav1,Osm,Clcf1,Sqstm1,Lmo4,Htr2b,Lgals9,Pik3r6,Ccl22,Mmp9,Sirt1,Jun,Fzd1,Tnf,Mapkbp1,Il1a,Ccl3,Daxx,Tpx2,Syk,Ccl4,Ccr1,Rasgrp1,Ccl12,Pik3r5,Angpt1,Nod1,Ifnb1,Ccl5,Icam1,Fgr,Map3k6,Igf1r,Cd40,Phip,Nox1,Fabp3,C3,Cd74,Tlr1,Malt1 |
| 1.875e-33 | -75.36 | regulation of apoptotic process | biological process | GO:0042981 | 1518 | 232 | 20694 | 1406 |
Mtdh,Cd40,Igf1r,Nox1,Phip,Ifnb1,Cdkn2d,Nod1,Irs2,Serpinb9,Ccl5,Hk1,Icam1,Insl6,Malt1,Nqo1,Cd74,Gclc,Syk,Cited2,Stxbp1,Jun,Sod2,Fam162a,Nsmaf,Tnf,Plk3,Ccl3,Daxx,Bfar,Angpt1,Atf3,Ciapin1,Pml,Eya4,Ccl12,Pim2,Asah2,Htr2b,Itpr1,Sell,Lyn,Cav1,Chst11,Osm,Slc7a11,Clcf1,Arel1,Arf4,Ier3,Mmp9,Sirt1,Grina,Axl,Acsl5,Cd274,Atm,Nes,Higd1a,Traf1,Bcl2a1d,Ifit2,Ptgs2,Hsph1,Rapgef2,Fam72a,Pik3cd,Cd38,Tax1bp1,Hspa1b,Plscr1,Dnaja1,Sp110,Edn1,Serpinb2,Serpine1,Nfkbid,Nod2,Lrp8,Fas,Gclm,Irak3,Itga4,Gadd45g,Zfp36,Sgk3,Sav1,Usp42,Tspo,Egln3,Adora2a,Phlpp1,Hdac1,Cx3cr1,S100a8,Il10,Acvr1,Plaur,Nr4a1,Tnfsf4,Map2k4,Uaca,Pim1,Hmox1,Irak2,Zc3h12a,Il18,Prokr1,Trip10,Notch1,Traf2,Mul1,Ripk2,Stk40,Casp4,Map4k4,Clec5a,Asns,Casp1,Notch2,Egr1,Rgcc,Bnip3,Bcl6,Gdf15,Ednrb,Il1rn,Agrn,Il12b,Gadd45b,Kdr,Dusp6,Bcl2a1b,Rffl,Kitl,Cx3cl1,Nck1,Ift57,Tnfsf10,Cdkn1a,Casp8,Pla2g4a,Fcgr2b,Casp3,Gja1,Itgav,Ikbkg,Nfkb1,4930453N24Rik,Tnfsf14,Cdk5r1,Prkce,Psmd10,Nr4a3,Mdm2,Btg2,Pmaip1,Il1b,Pim3,Il6,Ccnd2,Dusp1,Hif1a,Itga5,Cflar,Tnfrsf8,Lox,Cpeb4,Plk2,Thbs1,Mt1,Prnp,Casp2,Bmp2,Ctsc,Birc2,Col18a1,Spry2,Nupr1,Hcar2,Myc,Pde5a,Ptpn2,Plagl2,Pdgfrb,Ptk2,Ppp2r1b,Mecp2,Eef1e1,Dcun1d3,Plekhn1,Rnf34,Socs3,Stat5a,Pdpn,Eif2ak2,Slc9a1,Apaf1,Adrb2,Pf4,Birc3,Sphk1,Jak2,Prdx5,Stat1,Timp1,Nlrc4,Tnfaip3,Cycs,Inhba,Adar,Traf5,Ripk3,Optn,Plac8,Tnfrsf1b,Nlrp3,Klrk1,Cxcl10,Arg2,Lpar1,Tnfsf15,Nr3c1,Egr3,Src,Phlda1,Bcl2a1a,Stat3,Hck,Bcl2l11,Hcls1,Map2k1 |
| 2.492e-33 | -75.07 | GSE36527_CD62L_HIGH_VS_CD62L_LOW_TREG_CD69_NEG_KLRG1_NEG_UP | MSigDB lists | GSE36527_CD62L_HIGH_VS_CD62L_LOW_TREG_CD69_NEG_KLRG1_NEG_UP | 192 | 75 | 15632 | 1249 |
Fgl2,Tapbp,Dhx58,D1Ertd622e,Rffl,Slc15a3,Birc2,Ifit2,N4bp1,Daxx,Cd164,Apaf1,Ifit1,Crlf3,Hif1a,Fam133b,Stat2,Usp18,Isg15,Ch25h,Mxd1,Itga4,Rhoh,Pml,Lif,Oas2,Parp12,Trim26,Rab10,Hopx,Cd274,Irf7,Igsf9,Sp110,Ppp2r2a,Trafd1,Clic4,Slfn9,Kcna3,Cxcl10,Map3k8,Ttc39b,Serpinb9,Larp1,Parp9,Slfn8,Tor1aip2,Parp14,Irgm2,Znfx1,Rnf114,Psip1,Chmp4b,Tap1,Rbm43,Rtp4,Fas,Casp2,Il18rap,Trim21,Cysltr2,Htra1,Ifit3,Mov10,Tor3a,Tnfrsf1b,Wdr43,Aida,Irf1,Ifit3b,Asb13,Pim2,Oasl1,Stat1,Socs3 |
| 2.600e-33 | -75.03 | negative regulation of response to stimulus | biological process | GO:0048585 | 1561 | 236 | 20694 | 1406 |
Usp25,Spred1,Htra1,Lrp4,Hlx,Mul1,Sesn3,Map4k4,Nfkbil1,Dyrk2,Ptprj,Ldlr,Nmi,Aoah,Uaca,Gpr18,Hmox1,Cd300lf,Zc3h12a,Fgl2,Pid1,Rgs1,Rhoh,Notch1,Atp2b4,Ptger4,Adora2a,Phlpp1,Hdac1,Irf1,Plau,Cx3cr1,Il10,Ppp1r15b,Plaur,Acvr1,Tnfsf4,Socs7,Dnaja1,Tsku,Stap1,Sema4c,Cish,Serpine1,Nod2,Radx,Nfkbid,Tap2,Gclm,Irak3,Irf4,Ctla2a,Zfp36,Sgk3,Mmp14,Ptgir,Atm,Higd1a,Abr,Bcl2a1d,Ptgs2,Fam72a,Hsph1,Spn,Dusp5,Tank,Dusp2,Rgs3,Acod1,Itpr1,Ptch1,Htr2b,Klf7,Chst11,Cav1,Lyn,Ncoa7,Tnip1,Il4ra,Slc7a11,Kremen1,Trim30a,Myadm,Plcl2,Ier3,Sirt1,Mmp9,Grina,Lgals9,Dhx58,Tap1,Hhex,Sh3bp4,Pde3b,Bambi,Sod2,Fzd1,Mapkbp1,Tnf,Bfar,Prdm1,Angpt1,Atf3,Ccr1,Eya4,Ccl12,Asah2,Igf1r,Rbl1,Phip,Uchl1,Ifnb1,Cdkn2d,Ccl5,Rabgef1,Serpinb9,Icam1,Rpgrip1l,Pde4b,Aida,Parp3,Cd74,Gclc,Lif,Pdgfb,Arg2,Lpar1,Gpc1,Sema3c,Smpdl3b,Nr3c1,Bcl2a1a,Src,Fpr2,Map2k1,Stat1,Tlr6,Errfi1,Ncoa5,Tnfaip3,Trib1,Adar,Cd200,Vasn,Optn,Tnfrsf1b,Hk3,Rgs14,Akt3,Nlrp3,Phactr4,Tulp3,Rnf34,Znrf3,Socs3,Socs1,Slamf8,Adrb2,Nfkbia,Tlr9,Pf4,D1Ertd622e,Parp14,Ezr,Trafd1,Ddit4,Scyl2,Glrx,S1pr2,Dusp16,Spry2,Ptpn2,Clec2d,Nr1h3,Tle3,Il6,Hif1a,Dusp1,Cflar,Dusp8,Jag1,Thbs1,Plk2,Cd34,Grk3,Cacnb3,Prnp,Plek,Sema4a,Samhd1,Bmp2,Itgav,Gja1,Ikbkg,Tnfrsf14,Nfkb1,Nr4a3,Psmd10,Mdm2,Acp5,Il1b,Hmga2,Ppp2r3a,Pim3,Nlrc5,Ubash3b,Dusp6,Bcl2a1b,Rffl,Cx3cl1,Nck1,Met,Siglece,Cdkn1a,Casp8,Nampt,Fcgr2b,Mosmo,Calcrl,Egr1,Pmepa1,Tnip3,Bcl6,Gdf15,Fabp7,Dusp4,Samsn1,Ppp1r15a,Cst7,Rcan1,Il12b,Cgas,Il1rn,Txn1,Spred3,Mefv |
| 2.678e-33 | -75.00 | GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | 168 | 70 | 15632 | 1249 |
Oasl1,C3,Ifi35,Acsl1,Ldlr,Ccl4,Adam19,Jak2,Zcchc2,Cflar,Abtb2,Tor3a,Psmb8,Gem,Il10,Xaf1,Il18rap,Oas1a,Bcor,Usp25,P2ry14,Nlrp3,Plau,Zc3hav1,Aff1,Agrn,Sod2,Spsb1,Trim36,Myc,Stap1,Igsf6,Fcgr2b,Kcnj2,Scarf1,Oas1g,Rnf19b,Chic2,Ptgs2,Kcna3,Pim1,Clic4,Gtpbp2,Trafd1,Plaur,Il15ra,Pde4b,Txn1,Tap2,Slc7a5,Nmi,Ube2l6,Uba7,Oas2,Inhba,Ier2,Trim12c,Traf1,Kmo,Il1a,Icam1,Myd88,Cd164,N4bp1,Apobec3,Src,Parp8,Bcl6,Arid5a,Rbpms |
| 2.706e-33 | -74.99 | GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 1364 | 238 | 15632 | 1249 |
Gadd45b,Rnf114,Nlrc4,Ctsc,Mmp14,S1pr2,Gadd45g,Mid1,Ift57,Ifna5,Fas,Kat2b,Nr1h3,Cx3cl1,Cdk5r1,Pilrb2,Sdc4,Il27,Cd80,Rnf14,Tnfrsf1b,Ednrb,Cav1,Ifi211,Rictor,Egln3,Tlr9,Mmp9,C3,Lpar1,Ifi204,Fam162a,Dnajb2,Ifi209,Stat3,Rbpms,Glipr2,Ythdf1,Aim2,Plk3,Tab2,Psmb10,Apaf1,Pdgfc,Ifna2,Ccl3,Ccr1,Gja1,Fzd5,Map2k1,Pdgfrb,Osm,Ppp2r3a,Psmb6,Hmox1,Ripk2,Adora2b,Map3k8,Il18,Gcnt2,Kitl,Il1b,Htr2b,Keap1,Ezr,Map3k6,Flt1,Bcl2l11,Psmd10,Edn1,Irf4,Prkce,Nod2,Ccnd2,Nlrp3,Arrdc4,Htr2a,Tnfrsf14,Atp2b4,Angpt1,Birc3,Psmb8,Cysltr2,Ksr1,Sirt1,Rnf19a,Ifi203,Casp2,Rasgrp1,Casp7,Nox1,Mefv,Adrb2,Clcf1,Hsph1,Src,Cd40,Birc2,Casp3,Mdm2,Ccnd1,Psma6,Malt1,Lif,Il1a,Trim12c,Tnfrsf8,Mdfic,Jarid2,Plk2,Klf2,Pdgfb,Ifna6,Csf3,Ptger4,Rnf19b,Zc3h12a,Fpr1,Ptafr,Thbs1,Plaur,Vegfc,Spn,Eif2ak2,Sqstm1,Syk,Stap1,Ifnb1,Pde5a,Nck1,Mul1,Tpx2,Ifi214,Il15,Ifi207,S100a8,Atm,Ikbkg,Dcun1d3,Jdp2,Mndal,Casp8,Csf1,Psme2,Mmd,Sema4c,Ptk2,Itga5,Trib1,Lyn,Jak2,Polr2g,Rap2c,Ccl4,Cdkn1a,Tnf,Traf2,Bcl6,Serp1,Cycs,Hspa2,Nupr1,Rnf139,Cd74,Tnfaip3,Plek,Gdf15,Ccl5,Dusp6,Ppp1r15a,Lcp2,Inhba,Rapgef2,Fzd1,Tlr3,Crkl,Trib3,Pilrb1,Irak2,Cenpe,Nfkbia,Pik3r5,Ccl12,Jun,Tiparp,Spry2,Ccl2,Il6,Peli1,Ppp2r5a,Myc,Tlr6,Mapkapk2,Lrp8,Ccl22,Ifna1,Fbxo4,Gclc,Mark2,Ankib1,Ebi3,Socs3,Acvr1b,Irf1,Acsl1,Kdr,Hcls1,Prkar2b,Ifi213,Lrp4,Casp1,Psmb9,Ifi205,Dbnl,Acvr1,Acvrl1,Ube2e1,Psme1,Pml,Icam1,Sphk1,Nod1,Bmp2,Ripk3,Daxx,Txn1,Cd86,Pik3r6,Ifi208,Tnfsf15,Tlr1,Nmi,Larp1,Smc5,Dusp5,Pim1,Il12b,Tnfsf10 |
| 2.777e-33 | -74.96 | cytoplasmic part | cellular component | GO:0044444 | 8185 | 771 | 20747 | 1409 |
Ptgs2,Slc9a1,Tnip1,Dnajb2,Hp,Acp2,Srgn,Rffl,Fchsd2,Slc2a1,Birc3,Tor1aip2,Cd34,Tlr2,Slc25a22,Dusp6,Serpine1,Rac3,Chst11,Marcks,Icosl,Ifit1bl1,Sphk1,Nupr1,Nfkb1,Arel1,Igtp,Mgat1,Rtn1,Usp18,Atp11b,Sec24a,Malt1,Kmo,Pim1,Gmppb,Pmepa1,Nlrc5,Lrrc8c,Mmp13,Rhoq,Arid4a,Fscn1,Rhof,Tgfbi,Asns,Sav1,Acpp,Traf5,Riox2,Zbp1,Evl,Triobp,Inpp5b,Fut8,Acsl1,Tbc1d13,Ppp1r15b,Slc48a1,Stard7,Mthfd1l,Gsta3,Rnaset2a,Ifi205,Relb,Cox18,Ascc3,Nfkbil1,Aoah,Hilpda,Pkp4,Hspa1a,Slc31a2,Oasl1,Gcnt2,Pdss1,Rnf24,Slc30a4,Hif1a,Lpcat2,Ass1,Dennd1b,Tnfaip2,Pigv,Gca,Abcc4,Slc7a11,Rpgrip1l,Notch1,Slc49a4,Tlr6,Plscr1,Setdb2,Cpeb4,Stxbp1,Slc39a4,H2-Q6,Glrx,Ifi211,Tmem67,Iigp1,Acp5,Clic5,Gbp2,Parp9,Ahr,Sqstm1,Nqo1,Pdlim7,Fabp7,Klf6,Rai14,Rap1gap2,Il4i1,Fas,Larp1,Gsdmd,Tgtp2,Nmi,Cept1,Cenpj,Irf2,Hap1,Bcl2a1d,Arrdc4,Gbp8,B3gnt5,Snx2,Rab3ip,Plk3,Adhfe1,Nlrc4,Apaf1,Zc3hav1,Glipr2,Phldb1,Fam162a,Tapbpl,Fnbp1l,Tgtp1,Rmdn3,Optn,Fabp3,Tpi1,Rubcnl,P4ha1,Scyl2,Map2k1,Casp1,Slc37a3,Rnf19b,Cox17,Hspa2,Rrs1,Rnd1,Marcksl1,Casp4,Gch1,Tab2,Irs2,Fam129a,Dtx3l,Eno2,Trim12c,Fam72a,Jak2,Rrbp1,Gbp3,Prkce,Tnfrsf1b,Ch25h,Ctu1,Mx1,Ctsc,AA467197,Il1a,Wdr59,Arg2,Rab20,Ripk3,Ccdc88b,Cpd,Vasn,Snn,Ampd3,Ldlr,Lgals9,Psmb9,Tmod3,Oasl2,Clcn7,Gm12185,Bcl2a1b,Ptges,Arl5b,Stx11,Resf1,Dse,Sh3bp4,Mvp,Agtrap,Pfkl,Cxcl14,Micall2,Naa25,Minpp1,Csf1,Oas1a,Serp1,Sod2,Ap3m2,Kdr,Rabgef1,Clcn5,Dbnl,Carmil1,Zhx2,Bcl2l11,P2ry12,Spred1,Ggct,Herc6,Mmp14,Cyfip1,Ralgds,Mt1,Flrt2,Prdx5,Tomm70a,Gpc1,Cdc42ep4,Stx6,Lztfl1,Pgk1,Apba1,Rapgef2,Hk2,Tdrd7,Fmnl2,Rbpms,Tank,Sat1,Plagl1,Uaca,Vasp,Tent4a,Wdfy1,Mid1,Csrp1,Cav1,Pde5a,Ago3,Lnpk,Ppm1k,Slc44a1,Gpr85,Atp13a1,Mmd,Hk1,Dck,Stat3,St3gal3,Plpp3,Tlr9,Rbms2,Plk2,Prnp,Pmaip1,Eif2ak2,Ust,Fam241a,Sgms2,Slc31a1,Ktn1,Bcl9,Tlr1,Car13,Cflar,Actb,Casp8,Mrpl52,Ksr1,Dusp8,Cd74,Kdm4a,H2-Q4,Idi1,Lap3,Pfkfb3,Gm4951,Pnpt1,Gja1,Cgas,Tmem178,Cst7,Gramd1a,Mndal,Cmpk2,Txn1,Higd1a,Sp140,Hmgcs1,Mosmo,Itpr1,Eef1e1,Piezo1,Myd88,Igf2bp2,Cep350,Ift57,Zyx,Crkl,Cd38,Hk3,Dst,Ppp2r5a,Ric1,Clmp,Bcl2a1a,Homer1,Sema4c,Gypc,Il1b,Stau1,Smg7,Mthfr,Tulp3,Itgav,Errfi1,Pcx,Fcgr2b,Aftph,Cutc,Sco1,Ifit2,Mul1,Pde3b,Casz1,Mtus1,Prdx1,Myadm,Atm,B4galt4,Eno1,Dgkh,Gng4,Vps54,Tmem123,Mefv,Ikbkg,Gdf15,Rgs1,Dync1h1,Dyrk2,Myo1b,Dcp1a,Gng12,Prkar2b,Tlr3,Lrch3,Gsr,Src,G3bp2,Keap1,St3gal5,Sirt1,Syne2,Odc1,Bnip3,Dnaja1,Nlrp3,Rtn2,Clic4,Ifi47,Pim3,Il15,Clec5a,Slc25a37,Spry2,Cdk5r1,Armcx6,Cnp,Slc7a5,Dnase1l3,Chmp4b,Degs2,Gng11,Ptpn2,Selenow,F830016B08Rik,Ahrr,Dram1,Ero1l,Usp25,Nos2,Gclm,Dcun1d3,Trip10,Ets2,Rnf145,Aldh1b1,Hsd17b12,Rnf139,Cacna1d,Golga3,Atp11a,Gbp2b,Samd9l,Herc3,Adam19,Mtdh,Fgr,Pnp2,Ptk2,Psmd10,Nfkb2,Polr2g,Stat5a,Eif4g2,Stat2,Ranbp2,Cd164,Hck,Nfkbib,Dgka,Rel,Shfl,Lipe,Atp10a,Usp12,Rilpl1,Gbgt1,Mdm2,Ppp2r2a,Tnf,Kif3c,Tnfaip3,Psma6,P2ry2,Fndc3a,Ccnd2,Agrn,Palld,Cenpe,Cdkn2d,Hcls1,Tent2,Dennd2a,Edn1,St3gal6,Plaat3,Dek,Rnf114,Pttg1,Uchl1,Tap2,Carhsp1,Parp10,Srxn1,Trim21,9930111J21Rik1,Psd,Dennd6b,Gm4841,Mxd1,Tlk2,Pf4,Calcrl,Pdzd11,Lcn2,Ddit4,Coa5,Ifi203,Cers6,Ifi208,Serpinb9,Zfp36,Pikfyve,Vrk2,H2-Q7,Htr2a,Sla,Tpst1,Rhoh,F11r,Aim2,Osbpl3,Ddx60,Extl2,Slc4a7,Xaf1,Ddx4,Irf7,Ifitm1,Dnajb4,Treml4,Sbds,Flnb,Slc39a13,Hspa1b,Ak4,Cdkn1a,Socs7,Dhrs9,Alas1,Pdgfrb,Ifit1bl2,Pik3r5,Spata13,Oas1b,Acsl5,Parp14,Zc3h12a,Ubr4,Jarid2,Tha1,Myo10,Ahsa1,Bbx,Rab19,1600014C10Rik,Ntng2,Daam1,Top3a,Hsph1,Egln3,H2-Eb1,Txnrd1,Ifit1,Nox1,Stk40,Rbms1,Nr4a1,Shisa3,Me1,H2-Ab1,Bfar,Ifnar1,Fcho2,Lif,P4ha2,Etnk1,Zeb1,Cyth3,Jun,Casp7,Casp2,Rnf31,Cop1,Ccr3,Sele,Pml,Tasor2,Tspo,Fos,Esd,Gm5431,Kdm5b,Pdgfc,Cacybp,Oas1g,Vcam1,Mitd1,Fzd5,Tapbp,Bcl6,Kcnj2,Arl4a,Socs1,Gsap,Dock10,St3gal1,Ifi213,Ehd1,Tor3a,Irgm2,Gpr18,Anp32a,Whamm,Dusp16,Daxx,Sec24b,Sdc4,Gpd2,Lyn,Grina,Rnaset2b,Nek6,Procr,Nfkbie,Ptch1,Ptgir,Lnpep,Mcoln2,Rasgrp1,Crlf3,Stat1,Gbp7,Hmox1,Stat4,Ap3b1,Sgk3,Pla2g4a,Ext1,Gclc,Adrb2,Pstpip2,Tap1,Slc25a25,Tpm4,Syk,Ripk2,Flt1,Caml,Inhba,Rars,Slc16a1,Abcc1,Prkx,Kat2b,Ppp1r12b,Tut7,Acvr1b,Dock4,Nfkbia,Rab21,Plekhn1,Cx3cl1,Irgm1,Rsad2,Nod2,Pgap2,Sass6,Trim13,Rims3,Nat2,Tgs1,Msr1,Plekhf2,Etv6,Psat1,Rab10,Nck1,Agpat4,Cd274,Ikbke,Adap2,Mcmbp,Vezt,Milr1,Lcp2,Ezr,Tmtc2,Spire1,H2-Aa,Slc15a3,Rab9,Cdc42ep2,Mtfr2,Arl5c,S100a8,Rhoc,Dnaja2,Slamf7,Ldha,Rcn1,Abcc5,Oas3,Slc30a1,Mppe1,Ddx58,Trim36,Cnn3,Itga5,Mtcp1,Myc,Rab32,Lipg,Ifi207,Stxbp3,Rnf14,Ciapin1,Phyh,Plod3,Pdpn,Thbs1,Il15ra,Sema4a,Mov10,Plat,Ifi209,Stoml1,Pgs1,Rnd3,Mecp2,Lacc1,Snx10,Cycs,Ociad1,Rgs3,Ppfia3,Traf2,Rap2c,Slc25a12,Hdac1,F10,Lpar1,Pdk3,Map2k4,P2ry13,Mx2,Hsd17b7,Ccl2,Cd302,Maff,Nr3c1,Nfkbiz,Ifit3b,Asah2,Asap3,Gpsm2,Kmt5a,Gk,Abr,Atp2b4,Rab11fip1,Fam20c,Chic2,Ifi204,Gbp9,Slc29a3,Spsb1,Samsn1,Znrf1,Acod1,Mtmr14,Jmjd6,Cd14,Plekha5,Mthfd2,Hdc,Xrn1,Arf4,Pde4b,Trim14,Noct,Stap1,Ifit3,Mark2,Klf8,Psmb6,Flrt3,Cx3cr1,Mdn1,Ifi214,Map3k8,Ppp6r1,Ppp1r15a,Phlda1,Nt5c3,Dcp2,Dmxl2,Marf1,Grk3,Plod2,Rhbdf2,Wars,Rhou,Casp3,Oas2,Vcpip1 |
| 3.526e-33 | -74.73 | GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN | MSigDB lists | GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN | 183 | 73 | 15632 | 1249 |
Adora2b,Trib3,St7,Map3k8,Traf3ip2,Bcl2a1a,Ppp1r15a,Rrs1,Ccr1,Nampt,Junb,Dusp6,Gch1,Hk2,Btg2,Phlda1,Jmjd6,Ifih1,Plk3,Prdm1,Ier2,Mdfic,Myo10,Relb,Sla,Slc2a1,Birc2,Dusp1,Klf6,Tnf,Errfi1,Mafk,Tlk2,Bcl2a1d,Rsad2,Cish,Egr2,Irf1,Ier3,Socs3,Nfil3,Cflar,Ccl4,Ldlr,Zc3h12c,Marco,Il10,Gem,Eno2,Ppp1r15b,P4ha1,Kctd12,Csf1,Zfp36,Kat2b,Irs2,Nfkbiz,Atf3,Egr1,Me1,Slc25a25,Fos,Ets2,Tiparp,Cited2,Nr4a1,Nfkbia,Bcl2a1b,Tor1aip2,Myc,Il6,Peli1,Ccl2 |
| 3.771e-33 | -74.66 | GSE39864_WT_VS_GATA3_KO_TREG_UP | MSigDB lists | GSE39864_WT_VS_GATA3_KO_TREG_UP | 193 | 75 | 15632 | 1249 |
Traf3ip2,Cox18,Ptgs2,Grina,Pim1,Map3k8,Il12b,Cxcl10,Slfn3,Inpp1,Gcnt2,Htr2b,Nampt,Plk2,Slfn4,Inpp5b,Noc4l,Wars,Hap1,Mxd1,Ch25h,Pml,Mcoln2,Usp18,Zfp281,Gbp3,Socs1,Myd88,Apaf1,Gbp2,Stat5a,Ifit2,Psmb9,Timp1,Mgat1,Tpst1,Tank,Stat3,Phgdh,Egr2,Pnp2,Ccnd1,Rsad2,Ifi35,Casp7,Ppa1,Stat1,Dck,Il13ra1,Irf1,Acsl1,Lyn,Clcn7,Kdr,Gbp7,Casp4,Cnn3,Trim21,Csf1,Procr,Plscr1,Cdkn2d,Tlr6,Ccl22,Il4ra,Pim3,Pnpt1,Samhd1,Tap1,Ccl12,Irgm2,Pla2g4a,Ccl2,Il18bp,Vcan |
| 4.052e-33 | -74.59 | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | 404 | 112 | 15632 | 1249 |
Mdfic,Hif1a,Icam1,Il1a,Cebpd,C1ra,Nr3c1,Tbc1d1,Psmb9,Dse,Gpsm2,Ifi205,Ifi213,Axl,Casp1,Clmp,Gng12,Dcbld2,Igf2bp2,Fmnl2,Osbpl3,Serpinb2,Clic4,Ptgs2,Tgfbi,Lox,Dgka,Nmi,Antxr1,Ifi208,Phlda1,Myo1b,Nampt,Rgl1,Card6,Map4k4,Tuba4a,Rnd3,Plau,Rras2,Prnp,Spry2,Cflar,Tlr2,Adrb2,Pik3cd,Ell2,Stat4,Jag1,Ifi203,Met,Akt3,Htra1,Plscr1,Zc3h12c,Ifit3,Gna15,Casp4,Psmb8,Psat1,Birc3,Pdgfc,Tnfaip3,Lipg,Cd14,Upp1,Ogfrl1,B3gnt5,Stat3,Itgb8,Ifi44,Ifi209,Slc25a37,Cxcl1,Plat,Inpp1,Adora2b,Il18,Inhba,Cxcl2,Ext1,Tap2,Ifi207,Il15,Col4a2,Slc16a1,Pgm1,Ubash3b,Ifi214,Irs2,Nck1,Fas,Pla2g4a,Ctsc,Mmp14,Ptpn2,Trip10,Ets2,Frmd6,Rbms1,Fscn1,Gbp2b,Dnajb4,Ifi204,Rnf145,Ifit3b,Lyn,C3,Ifi211,Slpi,Cav1,Mndal |
| 4.052e-33 | -74.59 | MODULE_5 | MSigDB lists | MODULE_5 | 404 | 112 | 15632 | 1249 |
Il4ra,Gng11,Tnfrsf14,Angpt1,Tap1,Ccl12,Tspan3,Zyx,Il6,Stat1,Socs3,Il13ra1,Irf1,Acsl1,Ier3,Tlr2,Hcls1,Tnfaip2,Ltbp2,Marco,Casp4,Lcn2,Plscr1,Ifi203,Calcrl,Icam1,Sell,Fgr,Crim1,Hck,Ifi213,Cst7,Psmb9,Itpr1,Birc2,Ifi205,Pnp2,Ccnd1,Cd55,H2-Ab1,Tgfbi,Pim1,Il1rn,Thbs1,Tnfsf10,Plaur,Glrx,Nampt,Junb,Myo1b,Ube2l6,Ifi208,Maff,Sdc1,Ifi214,Cx3cl1,Cd34,Ifi207,Nr4a1,Ets2,Cited2,Ctsc,Vcan,Mmp9,Ifi204,Lyn,Rbms1,Ldlr,Adam19,Nfil3,Cdkn1a,S100a8,Tnfrsf1b,Cav1,Mndal,Cnn3,Ifi211,Slpi,Alas1,Nupr1,Upp1,Atp11a,Cd14,Sla,Tnfaip3,Mvp,P4ha2,Slc16a3,Mtus1,Cd302,Ifi209,Csf3r,Tnc,Stat3,Rbpms,Hp,Hmox1,Il2rg,Cxcl1,Acp2,Il1b,Fcgr4,Ccr1,Ccl5,Gja1,Csrp1,Dusp6,Ppp1r15a,Hopx,Lcp2,Pdgfrb,H2-Aa |
| 5.603e-33 | -74.26 | GSE17721_LPS_VS_PAM3CSK4_2H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_2H_BMDC_UP | 189 | 74 | 15632 | 1249 |
Gypc,Cst7,Tnf,Klf6,Slc25a37,Dusp1,Ttc39c,Arhgef3,P2ry12,Rab9,Pnp2,Batf2,Rab21,Sele,Nupr1,Lif,Ifih1,Isg15,Il1a,Ube2f,Crlf3,Pdgfc,Daxx,Gja1,Plek,Lcp2,Cd274,Sap30,Hk2,Csf3,Larp1,Arid5b,Gpr85,4930453N24Rik,Kcna3,Cldnd1,Serpinb2,Rsbn1,Ccl12,Fam43a,Jun,Ets2,Fos,Il6,Peli1,Ccl2,Aftph,Edn1,Ddx60,Nlrp3,Arl4a,Nxf1,Cd80,Sdc4,Rnd3,Plau,Eno2,Ptch1,Ifit3,Zfp36,Kctd12,Egln3,Ccrl2,Sirt1,Dck,Slc25a22,Ifit3b,Ldlr,Ccl4,Rgs1,Asf1a,Sh3bgrl2,Ap3m2,Nfil3 |
| 8.111e-33 | -73.89 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 1738 | 279 | 15632 | 1249 |
Cd74,Tnfaip3,Traf5,Sla,Cd14,Traf2,H2-Q6,Tnf,Rsad2,Dhx58,Gpr68,Crkl,Tlr3,Irak2,Ppp1r15a,Lcp2,Pde4b,Plek,Gdf15,Ccl5,Dusp6,Inhba,Rapgef2,Il12rb1,Cxcl2,Wdfy1,Mul1,Ifi214,Nck1,Ddx60,Ifi207,F10,Il15,Eif2ak2,Sqstm1,Syk,Pde5a,Ifnb1,Stap1,Lyn,Sema4c,Ptk2,Itga5,Jak2,Ccl4,Mndal,Casp8,Atm,S100a8,Nfkb1,Ikbkg,Slc9a1,Csf1,Psme2,Icam1,Intu,Sphk1,Fgr,Hhex,H2-Q7,Psme1,Pml,Ripk3,Daxx,Rhoc,Nod1,Bmp2,Psmb9,Swap70,Ifi205,Axl,Ifi213,Casp1,Acvr1,Acvrl1,C1ra,Dbnl,Dennd1b,Ptgs2,Il12b,Clec4d,Larp1,Ptprj,Cd55,Traf3ip2,Dusp5,Tnfsf10,Cd86,Pik3r6,Txn1,Hap1,Ifi208,Tlr1,Tnfsf15,Trim13,Ccl22,Phip,Il4ra,Mapkapk2,Tlr6,Cyfip1,Jun,H2-Q4,Nfkbia,Pik3r5,Ccl12,Spry2,Myc,Peli1,Il6,Ccl2,Acvr1b,Tlr2,Tnfsf4,Socs3,Hcls1,Kdr,Tnfsf14,Il10,Marco,C1rl,Clec4n,Rnf31,Pla2g7,Plscr1,Tab2,Ifih1,Psmb10,Aim2,Pdgfc,Apaf1,Cd38,Irak3,Plagl2,Ccl3,Myd88,Homer1,Ifi209,Ankrd17,Rbpms,Glipr2,Stat3,Adora2b,Map3k8,Il18,Nr4a3,Psmb6,Hmox1,Ripk2,Htr2b,Il1b,Cxcl1,Ikbke,Gcnt2,Kitl,Fzd5,Hopx,Serpine1,Irf7,Pdgfrb,Map2k1,Osm,H2-Eb1,Ccr1,Gja1,Ppp2r3a,H2-Aa,Mpp7,Cx3cl1,Nr1h3,Fas,Nek6,Enpp4,Spred1,Zc3hav1,Cd80,Clec4e,Nlrc4,Cited2,Ptpn2,Hmga1,Gadd45b,S1pr2,Gadd45g,Mid1,Scarf1,Ctsc,Bnip3,Pla2g4a,Ifi204,Cacnb3,Tnip3,Lpar1,Mtdh,Tlr9,Ptgir,Mmp9,C3,Pim2,Fam162a,Notch2,Ppp2r1b,Cav1,Rel,Tnfrsf1b,Rictor,Ifi211,Il1a,Hif1a,Ddx58,Cd180,Trim12c,Hlx,Malt1,Lif,Notch1,Relb,Myo10,Mdfic,Hck,Crlf3,Acpp,Birc2,Cd40,Hspa1a,Tank,Src,Psma6,Ptafr,Fpr1,Cxcl10,H2-Ab1,Ptger4,Zc3h12a,Plaur,Vegfc,Pf4,Cmklr1,Thbs1,Bambi,Plk2,Csf3,Wdr59,Pdgfb,Nlrp3,Atf3,Tnfrsf14,Angpt1,Fcgr1,Htr2a,Psmd10,Nlrc5,Map3k6,Flt1,Bcl2l11,Nod2,Cxcl14,Edn1,Prkce,Pik3cd,Adrb2,Nox1,Nlgn2,Gfi1,Actb,Cflar,Clcf1,Tnip1,Birc3,Psmb8,Jag1,Sirt1,Eef1e1,Met,Rasgrp1,Casp2,Ifi203,Cysltr2,Ksr1 |
| 8.262e-33 | -73.87 | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | 185 | 73 | 15632 | 1249 |
Map3k8,Shisa3,Traf3ip2,Dnaja2,Stip1,Il15ra,Glrx,Ptges,Cmpk2,Ikbke,Hsd17b12,Junb,Ccl5,Nfkbid,Slc2a6,Ddx58,Icam1,Upp1,Stat2,Ifih1,Ch25h,Ifit1,Relb,Gys1,Homer1,Rhbdf2,Birc2,Zmynd15,Ifit2,Nfkbie,Lztfl1,Stk40,Micall2,Gpr84,Tbc1d1,Slc15a3,Rffl,Cacnb3,Rab20,Ifit3b,Azi2,Ebi3,Denr,Dusp16,Abcc1,Ccl4,Tax1bp1,Ifit3,Casp8,Lcn2,Gbp7,Tor3a,Nfkb1,Zscan29,Hivep3,Rnf19a,Dcp1a,Xaf1,Trim21,Nfkbib,Rtp4,Enpp4,Pilra,Fbrsl1,Nfkbia,Gsdmd,Sqstm1,Pik3r5,Parp9,Ppfia3,Abcb1a,Stard5,Ccl2 |
| 8.489e-33 | -73.85 | GSE7509_DC_VS_MONOCYTE_DN | MSigDB lists | GSE7509_DC_VS_MONOCYTE_DN | 190 | 74 | 15632 | 1249 |
Olr1,Tap1,Klf7,Fcgr1,Clec4e,Tspo,Prdx1,F10,Nr1h3,Fpr2,Nck1,Irgm2,Gclm,Ets2,Znfx1,Sod2,Agrn,Slc7a11,Ezr,Klf3,Nfkbia,Gsta3,Rnaset2b,Acsl1,Ifit3b,Ptgir,Stat1,C3,Mtdh,Ifi35,Ccrl2,Psme2,Slpi,Procr,Srxn1,Casp4,Marco,Ifit3,Tnfrsf1b,S100a8,Tsku,Gbp2,Hck,Prpf38a,Clcn5,Cd14,Ifih1,Fgr,Traf1,Usp18,Nupr1,Ier2,Pnp2,Eno1,Tpst1,Cd302,Psmb9,Rgs14,Tnf,Acp2,Cmpk2,Glrx,Ptges,Clic4,Fpr1,Cxcl10,Hp,Cxcl2,Inhba,H2-Aa,Rnaset2a,Klf2,Snx10,Txn1 |
| 9.018e-33 | -73.79 | BROWNE_INTERFERON_RESPONSIVE_GENES | MSigDB lists | BROWNE_INTERFERON_RESPONSIVE_GENES | 57 | 41 | 15632 | 1249 |
Il15ra,Sp110,Tnfsf10,Ifit3b,Cxcl10,Ifi35,Tlr3,Stat1,Oas1g,Oasl1,Kif5c,Wars,Oas1a,Stx11,Xaf1,Tdrd7,Oas2,Trim21,Trim14,Isg20,Ube2l6,Plscr1,Nmi,Ifit3,Irf7,Rgl1,Psmb8,Gch1,Samhd1,Gbp2,Tap1,Il15,Myd88,Isg15,Pml,Rsad2,Ifi44,Psmb9,Eif2ak2,Ifit2,Casp1 |
| 1.171e-32 | -73.52 | regulation of cell activation | biological process | GO:0050865 | 562 | 124 | 20694 | 1406 |
Pdgfrb,Ctla2a,Ptpn2,Pde5a,Zeb1,Nr1h3,Nectin2,Mmp14,Stap1,Fas,Il15,Nod2,Nfkbid,Ccl2,Irf1,Slamf8,Tlr9,Adrb2,Tnfsf4,Il10,Bst1,Pdpn,Socs1,Ap3b1,Slfn1,Adora2a,Stat5a,Itgal,Zc3h12a,Tnfrsf1b,Slamf7,Fgl2,Il18,Cd300lf,Nlrp3,Tlr6,Jak2,Sphk1,Cd200,Ripk3,Hmox1,Clec4d,Tnfaip3,Il12rb1,Tarm1,Peli1,H2-Ab1,Egr3,Icosl,Ptprj,Ldlr,Arg2,Ptafr,Pdgfb,Klrk1,Ripk2,Hlx,Malt1,Samsn1,Bcl6,Il12b,Cgas,Gclc,Ccdc88b,Cst7,Parp3,Cd74,Vcam1,Fgr,Cd40,Ccl5,Rabgef1,Irs2,Ifnb1,Myd88,Ikzf1,Milr1,Nck1,Il27,Prdm1,Rasgrp1,Sdc4,Fcgr2b,Cdkn1a,Stxbp1,H2-Aa,Syk,Ubash3b,Cx3cl1,Slc7a2,Pik3r6,Il1b,Cd274,Cd83,Lgals9,Il15ra,Axl,Lmo4,Casp3,Nfkbiz,Ahr,Tnfsf14,Nr4a3,Clcf1,Cav1,Lyn,Tnfrsf14,Il4ra,Prnp,Tnfsf9,Plek,Plscr1,Cd38,Thbs1,Hsph1,Spn,Ctsc,Cd86,Adora2b,Atm,Il6,Cd80,Il2rg,Abr |
| 1.257e-32 | -73.45 | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | 201 | 76 | 15632 | 1249 |
Atf3,Nfkbiz,Sgms2,Pfkfb3,Rnd3,Dusp14,Ppfibp1,Olr1,Tle3,Aff1,Hivep2,Klf3,Nr4a1,Plac8,Ezr,Ets2,Tiparp,Fos,Il6,Peli1,Edn1,Ell2,Socs3,Ier3,Trib1,Rbms1,Tmem67,Frmd6,Igf1r,Dcun1d3,Nfkb1,Birc3,Gem,Sema3c,Zc3h12c,Jag1,Csrnp1,Il1a,Tnfaip3,Ncoa7,Txnrd1,Apobec3,Dusp1,Slc2a1,Otud1,Cebpd,B3gnt5,Mafk,Zc3h12a,Dusp5,Fndc3a,Kdm6b,Cd55,Nr4a3,Map3k8,Ptgs2,Rcan1,Cldnd1,Nfkb2,Cxcl1,Il1rn,Il1b,Plaur,Myadm,4930523C07Rik,Junb,Fosb,Serpine1,Plk2,Ppp1r15a,Arl5b,Phlda1,Maff,Stx11,Rapgef2,Sh3bp4 |
| 1.258e-32 | -73.45 | GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN | MSigDB lists | GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN | 186 | 73 | 15632 | 1249 |
Psmb9,Tpst1,P2ry13,Dpy19l1,Clmp,C1ra,Prdx5,Nr3c1,Gbp4,Egr2,Slc15a3,Gbp9,Cd74,Arg2,Fgr,Mcoln2,Ripk3,Etv5,Cd164,Myo10,Cd86,Cd274,Osm,Junb,Gja1,Ccl5,Gch1,Inhba,Bst1,Phlda1,Fpr1,Hp,Kdm6b,Smox,Gcnt2,Serpinb2,Gca,Msr1,Nlrc5,Fam43a,Flrt3,Vcan,Dtnb,Tmem171,Parp14,Spry2,Pla2g4a,Rai14,Sgms2,Fpr2,P2ry14,Dmxl2,Egr1,F10,Slc16a1,Gclc,Tspo,Mov10,Marco,Plekhg1,Mfap3l,Ikbkg,P4ha1,Ahrr,Pla2g7,Jag1,Ccrl2,Slpi,Lpar1,Azi2,Etnk1,Mmp9,Nfil3 |
| 1.350e-32 | -73.38 | positive regulation of defense response | biological process | GO:0031349 | 324 | 91 | 20694 | 1406 |
Irak2,Optn,Cd300lf,Ifi211,Mndal,Zc3hav1,Tlr6,Jak2,Nlrc4,Zbp1,Ddx58,Clec4e,Tlr2,Irf7,Tarm1,Peli1,Treml4,Trim12c,Ldlr,Il18rap,Ifi203,Fpr2,Pvr,Raet1e,Klrk1,Ikbke,Wdfy1,Tifa,Parp9,Ifi208,Ripk2,Irgm2,Pde5a,Irak3,Nr1h3,Nectin2,Ddx60,Stap1,Ifih1,Nupr1,Serpine1,Nod2,Fcgr1,Tlr9,Nfkbia,Tnfsf4,S100a8,H60b,Ptger4,Aim2,Stat5a,Cxcl1,Il1b,Dhx58,Lgals9,Mapkapk2,Gja1,Ifi205,Tlr3,Nfkbiz,Ifi209,Prkce,Cav1,Tnip1,Osm,Plscr1,Ctsc,Cd86,Adora2b,Il6,Ptgs2,Cd14,Ifi214,Il12b,Cgas,Tlr1,C3,Cd74,Ankrd17,Ccl5,Tnip3,Nod1,Irgm1,Myd88,Rasgrp1,Pla2g4a,Nlrc5,Tnf,Ifi204,Ccl3,Rsad2 |
| 1.457e-32 | -73.31 | positive regulation of multicellular organismal process | biological process | GO:0051240 | 1917 | 269 | 20694 | 1406 |
Spn,Cd38,Rapgef2,Adgrl2,Adora2b,Acsl1,Hilpda,Klf6,Cyfip1,Ptgs2,Fos,Mmd,Sirt1,Mmp9,Fam20c,Cd83,Cd274,Dhx58,Pik3r6,Axl,Irf8,Lgals9,Il15ra,Itpr1,Htr2b,Dbnl,Clcf1,Il4ra,Osm,Cav1,Lyn,Angpt1,Ikzf1,Il27,Prdm1,Rasgrp1,Pml,Ccr1,Ccl4,Bambi,Cited2,Syk,Rnf135,Ifi204,Il1a,Ccl3,Tnf,Fzd1,Rsad2,Sod2,Tcf4,Jun,Gsdmd,Malt1,Pde4b,Lipg,Tlr1,C3,Cd74,Dync1h1,Igf1r,Cd40,Fgr,Mtdh,Nlgn2,Ankrd17,Icam1,Hk1,Ccl5,Kat2b,Nod1,Csf3,Gcnt2,Icosl,Clec5a,Casp4,Map4k4,Ptprj,Casp1,Hap1,Traf2,Scn1b,Mul1,Ripk2,Hlx,Il18,Zc3h12a,Notch1,Scarf1,Trip10,Hmox1,Tlr2,Pim1,Clec4e,Irf1,Plau,Hdac1,Tnfsf4,Acvr1,Rab21,Il10,Cx3cr1,Kif3c,Mmp13,Cmklr1,Ptger4,Mcoln2,Abcb1a,Plpp3,Adora2a,Aim2,Ehd1,Tspo,Irf4,Gadd45g,Irak3,Ccr3,Enpp4,Itgb8,Phldb1,Mmp14,Ddx60,Edn1,D16Ertd472e,Lrp8,Nod2,Nfkbid,Flrt2,Serpine1,Plek,Tnfsf9,Cd34,Cacnb3,Thbs1,Plk2,Bmp2,Sema4a,Rel,Itga5,Hif1a,Acvr1b,Kdm4a,Il6,Jag1,Tnfrsf8,Il2rg,Cflar,Pdgfc,Hmga2,Isg15,Il1b,Fubp1,Mapkapk2,Ifnar1,Gja1,Tlr3,Nfkbiz,Hk2,Ifi205,Plat,Nr4a3,Prkce,Ccnd1,Tnfrsf14,Myd88,Serp1,Met,Acvrl1,Nck1,Gch1,Arid5a,Etv5,Casp8,Kdr,H2-Aa,P2ry2,Cx3cl1,Kitl,P2ry12,Pdlim7,Cd14,Ednrb,Bcl6,Il12b,Agrn,Kdm6b,Cgas,Il1rn,Mark2,Cst7,Ccdc88b,Rgcc,Egr1,Notch2,Stat3,Src,Peli1,Egr3,Nr3c1,Gpr68,Sema3c,Map2k1,Hcls1,Eif4g2,Lcn2,Ptafr,Flt1,Lif,Pdgfb,Klrk1,Gpc1,Tnfsf15,Lpar1,Tnfrsf1b,Plac8,Optn,Clec4n,Ifi211,Nlrp3,Mndal,Zc3hav1,Akt3,Rgs14,Stat1,Flrt3,Jak2,Tlr6,Crkl,Sphk1,Cysltr2,Ddx58,Cd200,Il12rb1,Tarm1,Inhba,Trib1,Irf7,Tnfaip3,Ccl2,Adrb2,Pf4,Tlr9,Slc9a1,Ezr,Dio2,Vegfc,Mecp2,Eif2ak2,Pdpn,Ap3b1,Socs1,Glipr2,Stat5a,Cxcl1,Cebpd,Fcgr4,Pdgfrb,Fzd5,Htr2a,Pde5a,Myc,Zeb1,Kdm5b,Ptk2,Ifih1,Spen,Hcar2,Il15,Csf1 |
| 1.464e-32 | -73.30 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | 153 | 66 | 15632 | 1249 |
Ifi211,Oas1a,Xaf1,Ifi203,Cd69,Cav1,Ifit3,Mndal,Gbp2b,Ifi35,Oasl1,Stat1,Ifi204,Ifit3b,Parp14,Pla2g4a,Parp9,Samd9l,Phactr4,Ifit1bl1,Eif2ak2,Ifi207,Angpt1,Ahr,Ddx60,Dmxl2,Ifi214,Arrdc4,Ifi208,Parp12,Oas2,Ifit1bl2,Hopx,Irf7,Bambi,Epsti1,Cmpk2,Sp110,Herc6,Oas1g,Rtn1,Ptgs2,Arid5b,Lox,Cxcl10,Ifi44,Itgb8,Rbpms,Rsad2,Ifit2,Ifi213,Arhgef3,Ifi209,Oas3,Ifi205,Ncoa7,Mvp,Hlx,Parp10,Ch25h,Usp18,Stat2,Ddx58,Ifih1,Isg15,Dtx3l |
| 1.914e-32 | -73.03 | GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_DN | MSigDB lists | GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_DN | 197 | 75 | 15632 | 1249 |
Slfn3,Gcnt2,Il15ra,Hmox1,Tgfbi,Pim1,Map3k8,Cxcl10,Inpp5b,Ccr1,Jarid2,Nampt,Map4k4,Gja1,Cd86,Slfn4,Lcp2,Lgals9,Myd88,Apaf1,Gbp2,Ch25h,Mxd1,Pml,Mcoln2,Zfp281,Isg15,Psmb10,Socs1,Gbp3,Stat3,Pnp2,Fgl2,Tlk2,Cebpd,Stat5a,Ifit2,Casp1,Timp1,Psmb9,Tpst1,Mgat1,Ccl4,Kdr,Dusp16,Stat1,Il13ra1,Irf1,Ier3,Cnn3,Plscr1,Zfp36,Ednrb,Gbp7,Casp4,Fcgr1,Pnpt1,Tspo,Tle3,Tap1,Nfkbiz,Tlr6,Ccl22,Il4ra,Irgm2,Ikzf1,Ctsc,Pla2g4a,Fcgr2b,Ccl2,Vcan,Il18bp,Gadd45g,Ccl12,Jun |
| 1.930e-32 | -73.03 | GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN | 192 | 74 | 15632 | 1249 |
Uba7,Wars,Noc4l,Gpr132,Vps54,Hopx,Slfn4,Nampt,Slfn3,Gtpbp2,Il18,Cxcl10,Pcgf5,Traf3ip2,Fgl2,Glipr2,Stat3,Tpst1,Cd40,Psmb9,Swap70,Tnf,Ifit2,Gbp2,Tnfaip3,Ifit1,Daxx,Sla,Gnb4,St3gal6,Psmb10,Socs1,Gbp3,Upp1,Usp18,Pml,Prdm1,Mxd1,Il18rap,Flnb,Trim21,Cnn3,Csf1,Ksr1,Gbp7,Casp4,Ifit3,Rnf14,Ltbp2,Ahrr,Tor3a,Psmb8,Abcc1,Esd,Kdr,Tnfaip2,Dr1,Ier3,Gpd2,Ifit3b,Irf1,Stat1,Ifi35,Gadd45g,Myc,Ctsc,Jun,Znfx1,Cx3cr1,Rbl1,Tap1,Adar,Nxf1,Abr |
| 2.369e-32 | -72.82 | GROSS_HYPOXIA_VIA_ELK3_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_DN | 154 | 66 | 15632 | 1249 |
Nfil3,Il13ra1,C3,Mthfd2,Ifi204,Slpi,Zfp36,Ifi211,Ifi203,Jag1,Slc39a14,S100a8,Rabgef1,Mndal,Pim3,Pfkfb3,Ifi207,Aff1,Egr1,Rars,Atf3,Ifi214,Gbe1,Myc,Il6,Dusp2,Edn1,Spry2,Dusp4,Ifrd1,Dhrs9,Slc7a11,Ccl12,Nfkbia,Fos,Cxcl1,Smox,Ptger4,Cxcl10,Ptgs2,Rcan1,Chic2,Ifi208,Oas2,Csf3,Tshz1,Gja1,Plek,Higd1a,Asns,Plk2,Ppp1r15a,Samsn1,Csrnp1,Rnd1,Upp1,Sat1,Tnc,Prdx5,Errfi1,Klf6,Ifi213,Eno1,Ifi209,Slc2a1,Ifi205 |
| 2.383e-32 | -72.81 | positive regulation of protein modification process | biological process | GO:0031401 | 1221 | 199 | 20694 | 1406 |
Notch2,Rgcc,Egr1,Gdf15,Bcl6,Ednrb,Ppp1r15a,Gadd45b,Agrn,Il12b,Txn1,Il1rn,Kdr,Kitl,Mdfic,Cx3cl1,Ifna6,Myd88,Met,Acvrl1,Cdkn1a,Sdc4,Fcgr2b,Arid5a,Tlr3,Ikbkg,Ppp2r5a,Tnfrsf14,Prkce,Cdk5r1,Psmd10,Ccnd1,Mlkl,Ifna1,Pdgfc,Trib3,Il1b,Il6,Itga5,Acvr1b,Ccnd2,Cflar,Mid1,Grk3,Thbs1,Fbxo4,Prnp,Bmp2,S1pr2,Hspa2,Birc2,Dnajb2,Spry2,Il15,Nupr1,Csf1,Htr2a,Ccl8,Pde5a,Pdgfrb,Fzd5,Ptk2,Ccl9,Dcun1d3,Vegfc,Mecp2,Ifna2,Rbpms,Glipr2,Map3k8,Eif2ak2,Ccl7,Tlr9,Arrdc4,Adrb2,Fcgr1,Ccl2,Parp14,Birc3,Crkl,Sphk1,Tlr6,Jak2,Rictor,Inhba,Trib1,Ripk3,Cysltr2,Scimp,Lif,Pdgfb,Flt1,Tnfsf15,Lpar1,Tnks1bp1,Src,Peli1,Fpr2,Map2k1,Hcls1,Igf1r,Cd40,Map3k6,Nox1,Phip,Jdp2,Kat2b,Nod1,Ifnb1,Icam1,Ccl5,Malt1,C3,Cd74,Tlr1,Syk,Tpx2,Ccl4,Fzd1,Jun,Daxx,Ccl3,Il1a,Mapkbp1,Tnf,Pik3r5,Angpt1,Pml,Ccr1,Rasgrp1,Ccl12,Sqstm1,Htr2b,Tnip1,Osm,Lyn,Cav1,Clcf1,Ccl22,Mmp9,Sirt1,Lgals9,Pik3r6,Cd80,Atm,Acsl1,Higd1a,Ksr1,Mmd,Ahrr,Ptgs2,Spn,Hsph1,Rapgef2,Fam129a,Tank,Rap2c,Sema4c,Stap1,Edn1,Nod2,Mtcp1,Fas,Nsd3,Lrp8,Gadd45g,Atp2b4,Ptger4,Plpp3,Cenpe,Hdac1,Cx3cr1,Map2k4,Ppp1r15b,Plaur,Acvr1,Marco,Tlr2,Pim1,Irak2,Il18,Zc3h12a,Notch1,Nek6,Ifna5,Traf2,Irgm2,Ifna4,Lrp4,Parp9,Mul1,Ripk2,Tab2,Map4k4,Csf3,Gcnt2,Jarid2,Ptprj,Nmi |
| 2.699e-32 | -72.69 | GSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP | MSigDB lists | GSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP | 178 | 71 | 15632 | 1249 |
Parp14,Irgm2,Gpr18,Znfx1,Plac8,Gsdmd,Ifit1bl1,Enpp4,Sgcb,Zbp1,Cdc42ep2,Rbm43,Coa5,Gmppb,Ccrl2,Oas1a,Isg20,Csf1,Clec4n,Tor3a,Psmb8,Hk1,Tmem219,Parp11,Irf1,Lyn,Casp7,Ptk2,Stat1,Denr,Tapbp,Rsad2,Pde1b,Batf2,Psmb9,Itpr1,Cd40,Oas3,Parp8,Gbp2,Nod1,Traf5,1600014C10Rik,F11r,Rab19,Spata13,Ddx58,Dtx3l,Socs1,Gbp3,Trim12c,Zfp513,Il12rb1,Parp12,Adora2a,Oas2,Daam1,Cd86,Lgals9,Slfn4,Irf7,Ifit1bl2,Gch1,Epsti1,Trafd1,Tfec,Slfn3,Serpinb9,Frmd4a,Tapbpl,Oas1g |
| 2.699e-32 | -72.69 | GSE42724_MEMORY_VS_B1_BCELL_DN | MSigDB lists | GSE42724_MEMORY_VS_B1_BCELL_DN | 178 | 71 | 15632 | 1249 |
Dse,Traf2,Cd40,Eno1,Ehd1,C1ra,Sat1,F11r,Traf1,Gbp3,Parp10,Csrnp1,Mcoln2,Relb,Tnfaip3,Lad1,Hopx,Cd274,Pde4b,Txn1,Ccl5,Gch1,Inhba,Nfkbid,AA467197,Gpr132,Slc2a6,Scn1b,Ak4,Arid5b,Dusp5,Epsti1,Il15ra,Plat,Znfx1,Rhof,Ptpn2,Trip10,Gramd1a,Nfkbia,Gadd45b,Bcl2l11,Sod2,Slc7a11,Optn,Parp9,Dusp4,Slc44a1,Nfkbiz,Tap1,Pim3,Sdc4,Abtb2,Psmb8,Nfkb1,Rnf31,Stat4,Rasgrp1,Isg20,Irf1,Ebi3,Socs3,Pim2,Cd200,Hsd17b7,Cdkn1a,Fscn1,Cflar,Idi1,Ldlr,Tnfaip2 |
| 2.807e-32 | -72.65 | GSE41867_NAIVE_VS_DAY30_LCMV_CLONE13_EXHAUSTED_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY30_LCMV_CLONE13_EXHAUSTED_CD8_TCELL_UP | 159 | 67 | 15632 | 1249 |
Abtb2,Il18rap,Tdrd7,Rnf19a,Oas1a,Ampd3,Lyn,Tnip3,Oasl1,Stat1,Ifi35,Dgkh,Ppfibp2,Ccl4,Ust,Cflar,Znfx1,Pik3r5,Samd9l,Vcan,Il6,Peli1,Stard5,Parp14,Kcnj2,Xrn1,Nxf1,Zc3hav1,Adar,Slamf7,Pim3,Sdc4,Serpine1,Sipa1l1,Ppp1r15a,Map4k4,Ccl5,Gch1,Nampt,Plek,Stx11,Adora2a,Ube2l6,Map3k8,Ptgs2,4930453N24Rik,Oas1g,Dusp5,Ripk2,Herc6,Snn,Epsti1,Cd40,Birc2,Oas3,Stat5a,Ehd1,Errfi1,Ifih1,Usp18,Ddx58,Pml,Csrnp1,Aim2,Plk3,Mxd1,Cd83 |
| 2.822e-32 | -72.65 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_UP | 183 | 72 | 15632 | 1249 |
Slc2a6,Inhba,Cxcl2,Nampt,Myo1b,Acsl5,Cxcl1,Clic4,Plat,Plaur,Gng12,Il15ra,Il1b,Dusp5,Zc3h12a,Ptgs2,Slc43a3,Grina,Ptafr,Il12b,Nfkbie,Hspa2,Ehd1,Src,Tpst1,Rhbdf2,Tank,Batf,Etv5,Hck,Plagl2,Mxd1,Upp1,Icam1,Il1a,Traf1,Procr,Ampd3,Pdss1,Nfkbib,Stat4,Nfkb1,Tnfrsf1b,Casp4,Siglece,Ccl4,Tnip1,Trem1,Ebi3,Socs3,Pim2,Tnip3,Lpar1,Trib1,Ier3,Lyn,Acsl1,Tlr2,Kcnj2,Pdpn,Il6,Dusp2,Gadd45b,Nfkbia,Agrn,Sod2,Slc7a11,Dnaja1,Trip10,Ets2,Cd80,Fpr2 |
| 2.854e-32 | -72.63 | regulation of intracellular signal transduction | biological process | GO:1902531 | 1585 | 236 | 20694 | 1406 |
Cx3cr1,S100a8,Map2k4,Plaur,Phlpp1,Hdac1,Ptger4,Atp2b4,Bst1,Cmklr1,Ddx60,Gadd45g,Irak3,Nfkbid,Nod2,Fas,Dnaja1,Sema4c,Edn1,Casp1,Hap1,Rrs1,Ptprj,Map4k4,Dyrk2,Gcnt2,Csf3,Stk40,Sesn3,Ripk2,Mul1,Tifa,Cyth3,Tab2,Wdr59,Spred1,Traf2,Notch1,Rhoh,Irak2,Il18,Itgal,Zc3h12a,Tlr2,Gpr18,Uaca,Marco,Ccr1,Atf3,Pim2,Ccl12,Ago3,Rasgrp1,Prdx1,Pik3r5,Angpt1,Sod2,Jun,Ccl3,Il1a,Mapkbp1,Tnf,Pde3b,Syk,Sh3bp4,Ccl4,Cd74,C3,Tlr1,Aida,Rnf31,Pde4b,Malt1,Cdkn2d,Nod1,Uchl1,Icam1,Rabgef1,Ccl5,Cd40,Psd,Igf1r,Ankrd17,Map3k6,Mtdh,Fgr,Vrk2,Nox1,Arhgef3,Adora2b,F10,Dusp2,Rapgef2,Hsph1,Plscr1,Dusp5,Tank,Bcl2a1d,Ksr1,Abr,Ptgs2,Atm,Axl,Trim13,Grina,Pik3r6,Dhx58,Ccl22,Mmp9,Sirt1,Osm,Tnip1,Lyn,Cav1,Clcf1,Myadm,Sqstm1,Htr2b,Itpr1,Ezr,Birc3,Glrx,Ddit4,Adrb2,Tlr9,Slc9a1,Ccl2,Glipr2,Map3k8,Eif2ak2,Ccl7,Card6,Eef1e1,Rnf34,Ptk2,Ccl9,Prag1,Htr2a,Pde5a,Ccl8,Ptpn2,Fzd5,Pdgfrb,Plagl2,Mob3b,Spry2,Csf1,Nupr1,Birc2,Dusp16,Sipa1l1,Fpr2,Map2k1,Hcls1,Bcl2a1a,Src,Bcl2l11,Peli1,Tnfsf15,Lpar1,Pdgfb,Lif,Flt1,Akt3,Rgs14,Zc3hav1,Scimp,Nlrp3,Clec4n,Optn,Rictor,Tnfaip3,Trib1,Inhba,Cysltr2,Traf5,Ripk3,Crkl,Sphk1,Rap1gap2,Errfi1,Tlr6,Jak2,Stat1,Casp8,Spata13,Fcgr2b,Nck1,Tnfsf10,Met,Myd88,Gpr35,Arhgap26,Rffl,P2ry12,Kitl,Mdfic,Cx3cl1,Sik3,Bcl2a1b,Dusp6,Kdr,Rcan1,Spred3,Gadd45b,Traf3ip2,Cgas,Il1rn,Dusp4,Gdf15,Bcl6,Cd14,Notch2,Tnip3,Kmt5a,Bmp2,Thbs1,Prnp,Cflar,Dusp8,Mid1,Il6,Dusp1,Hif1a,Pmaip1,Trib3,Il1b,Mlkl,Mdm2,Pdgfc,Psd4,Prkce,Psmd10,Tnfsf14,Tlr3,Ikbkg |
| 2.887e-32 | -72.62 | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN | 188 | 73 | 15632 | 1249 |
Tap1,Samhd1,Adar,Il15,Gmppb,Kat2b,Usp25,Pgs1,Irgm2,Tor1aip2,Znfx1,Slc7a11,Srm,Agrn,Eif2ak2,Plac8,Gfi1,Gsta3,Ldlr,Mthfd2,Ifit3b,Acsl1,Stat1,Ppa1,Ebi3,Ifi35,Mtdh,Etnk1,Ccrl2,Trim21,Isg20,Ogfr,Casp4,Ifit3,Mov10,Daxx,Ifit1,Slco3a1,Ifih1,Isg15,Usp18,Mthfr,Pml,Atp13a1,Rsad2,Tapbp,Pnp2,Plekha5,Ifit2,Trafd1,Cmpk2,Gng12,Il15ra,Nfkb2,Clic4,Gtpbp2,Slfn3,Cxcl10,Map3k8,Serpinb9,Pim1,Cox18,Rnf19b,Uba7,Il12rb1,Nmi,Noc4l,Gpr132,Irf7,Slfn4,Lgals9,Brd2,Nampt |
| 3.373e-32 | -72.47 | positive regulation of protein phosphorylation | biological process | GO:0001934 | 1001 | 175 | 20694 | 1406 |
S1pr2,Hspa2,Il15,Csf1,Spry2,Pdgfrb,Fzd5,Htr2a,Ccl8,Pde5a,Ccl9,Ptk2,Ifna2,Rbpms,Vegfc,Ccl7,Eif2ak2,Glipr2,Map3k8,Ccl2,Adrb2,Tlr9,Fcgr1,Parp14,Jak2,Tlr6,Crkl,Sphk1,Ripk3,Cysltr2,Rictor,Inhba,Scimp,Flt1,Lif,Pdgfb,Tnfsf15,Lpar1,Src,Tnks1bp1,Map2k1,Hcls1,Fpr2,Rgcc,Egr1,Notch2,Ednrb,Ppp1r15a,Gdf15,Gadd45b,Il12b,Agrn,Il1rn,Txn1,Kdr,Mdfic,Cx3cl1,Kitl,Myd88,Met,Acvrl1,Ifna6,Sdc4,Fcgr2b,Cdkn1a,Ikbkg,Tlr3,Psmd10,Cdk5r1,Prkce,Ccnd1,Tnfrsf14,Pdgfc,Ifna1,Mlkl,Il1b,Acvr1b,Itga5,Ccnd2,Il6,Mid1,Cflar,Prnp,Grk3,Thbs1,Bmp2,Sema4c,Edn1,Stap1,Fas,Lrp8,Nod2,Mtcp1,Gadd45g,Cenpe,Atp2b4,Ptger4,Plpp3,Hdac1,Map2k4,Acvr1,Plaur,Cx3cr1,Marco,Tlr2,Pim1,Il18,Zc3h12a,Irak2,Notch1,Ifna5,Traf2,Nek6,Tab2,Irgm2,Ifna4,Lrp4,Parp9,Mul1,Ripk2,Gcnt2,Csf3,Map4k4,Ptprj,Nox1,Phip,Igf1r,Cd40,Map3k6,Icam1,Ccl5,Ifnb1,Nod1,Malt1,Tlr1,C3,Cd74,Ccl4,Syk,Tpx2,Ccl3,Il1a,Daxx,Tnf,Mapkbp1,Fzd1,Jun,Angpt1,Pik3r5,Rasgrp1,Ccl12,Ccr1,Htr2b,Sqstm1,Clcf1,Osm,Lyn,Cav1,Sirt1,Mmp9,Ccl22,Pik3r6,Lgals9,Acsl1,Higd1a,Cd80,Atm,Ptgs2,Ksr1,Mmd,Fam129a,Spn,Rapgef2,Hsph1,Rap2c |
| 3.475e-32 | -72.44 | positive regulation of phosphorylation | biological process | GO:0042327 | 1056 | 181 | 20694 | 1406 |
Mdfic,Cx3cl1,Kitl,Kdr,Sdc4,Fcgr2b,Cdkn1a,Myd88,Met,Acvrl1,Ifna6,Rgcc,Egr1,Notch2,Gadd45b,Il12b,Agrn,Il1rn,Txn1,Ednrb,Ppp1r15a,Gdf15,Mid1,Cflar,Acvr1b,Itga5,Ccnd2,Il6,Bmp2,Prnp,Grk3,Thbs1,Prkce,Psmd10,Cdk5r1,Ccnd1,Tnfrsf14,Ikbkg,Tlr3,Il1b,Ifna1,Pdgfc,Mlkl,Ccl7,Eif2ak2,Glipr2,Map3k8,Ifna2,Rbpms,Vegfc,Parp14,Ccl2,Tlr9,Adrb2,Fcgr1,Il15,Nupr1,Csf1,Spry2,S1pr2,Hspa2,Ccl9,Ptk2,Pdgfrb,Fzd5,Htr2a,Ccl8,Myc,Pde5a,Tnfsf15,Lpar1,Flt1,Lif,Pdgfb,Map2k1,Hcls1,Fpr2,Src,Tnks1bp1,Ripk3,Cysltr2,Rictor,Inhba,Pgk1,Tlr6,Jak2,Crkl,Sphk1,Scimp,Ranbp2,Ccl3,Il1a,Daxx,Tnf,Mapkbp1,Fzd1,Jun,Ccl4,Syk,Tpx2,Rasgrp1,Ccl12,Ccr1,Angpt1,Pik3r5,Icam1,Ccl5,Nod1,Ifnb1,Nox1,Phip,Igf1r,Cd40,Fgr,Map3k6,Tlr1,C3,Cd74,Malt1,Ptgs2,Ksr1,Mmd,Acsl1,Higd1a,Cd80,Atm,Rap2c,Fam129a,Spn,Hsph1,Rapgef2,Clcf1,Osm,Cav1,Lyn,Htr2b,Lmo4,Sqstm1,Pik3r6,Lgals9,Mmp9,Sirt1,Ccl22,Cenpe,Atp2b4,Ptger4,Plpp3,Map2k4,Acvr1,Plaur,Cx3cr1,Hdac1,Fas,Lrp8,Nod2,Mtcp1,Sema4c,Stap1,Edn1,Gadd45g,Tab2,Irgm2,Ifna4,Lrp4,Parp9,Ripk2,Mul1,Ifna5,Traf2,Nek6,Ptprj,Gcnt2,Csf3,Map4k4,Tlr2,Pim1,Marco,Notch1,Il18,Zc3h12a,Irak2 |
| 5.736e-32 | -71.94 | response to interferon-beta | biological process | GO:0035456 | 55 | 38 | 20694 | 1406 |
Ifi203,Ifi207,Gbp3,Ifit3,Gbp2,Irgm1,Plscr1,Irf1,Ifi208,Irgm2,Ikbke,Aim2,Ifi204,Ifi213,Pnpt1,Gm4951,9930111J21Rik1,Xaf1,Gm5431,Gbp2b,Ifit1,Iigp1,Gm4841,Tgtp2,Mndal,Ifi211,Ifitm1,Gm12185,Ifi47,Ifi214,Ifnb1,Igtp,Ifi209,Ifi205,Tgtp1,F830016B08Rik,Stat1,Acod1 |
| 6.362e-32 | -71.83 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | 753 | 160 | 15632 | 1249 |
Sat1,Rab11fip1,Rsad2,Ccng2,Klf6,Armcx6,P4ha2,Abcc5,Txnrd1,Mtus1,Arhgef3,Ifi209,Serp1,Plagl2,Plk3,Prrg4,F11r,Upp1,Ddit4,Stxbp3,Inhba,Mmp13,Cxcl2,Cdyl,Gdf15,Brd2,Ppp1r15a,Irf7,Gtpbp2,Cxcl1,Kitl,Sec24a,Ralgds,Ppp2r2a,Snn,Fam53c,Hmox1,Ripk2,Rcan1,Trib3,Il18,Gclm,Pla2g4a,Optn,Cnot4,Morc3,Trim36,Spsb1,Klf3,Ass1,Sqstm1,Sod2,Dnaja1,Ets2,Cited2,Il15,Ifi207,Ahr,Zc3hav1,Palld,Irs2,Ifi214,Slc30a1,Nxf1,Ifi211,Rtn2,Zfp36,Cenpj,Mndal,Gem,Sik3,Gfpt1,Dnajb2,Nfil3,Cdkn1a,Oasl1,Ifi204,Trib1,Dnajb4,Mthfd2,Rhoq,Rab9,Acvr1,Kdm5b,Cebpd,Hsph1,Src,Ifi213,Dusp1,N4bp1,Dse,Swap70,Ifi205,Tank,Ahsa1,Bmp2,Notch1,Relb,Kdm4a,Il1a,St3gal6,Socs1,Jmjd6,Phlda1,Ifi208,Maff,Rgl1,Ccnj,Slc31a2,Nampt,Slc4a7,Daam1,Serpinb2,Sec24b,Zhx2,Cd55,Smox,Kdm6b,Rnf19b,Smc5,Zc3h12a,Dusp5,Ptgs2,Chic2,Pim1,Lox,Nsmaf,Kif3c,Spry2,Il6,Hivep2,Nfkbia,Slc7a11,Fos,Rhof,Tiparp,Rras2,Pfkfb3,Rnd3,Hinfp,Gclc,Atp2b4,Atf3,Trim13,Zc3h7a,Ampd3,Slc39a14,Sirt1,Dcp1a,Ifi203,Abtb2,Rabgef1,Clcf1,Igf1r,Irf1,Acvr1b,Mafg,Ier3,Azi2,Tlr2 |
| 9.243e-32 | -71.46 | GSE42021_CD24INT_VS_CD24LOW_TREG_THYMUS_DN | MSigDB lists | GSE42021_CD24INT_VS_CD24LOW_TREG_THYMUS_DN | 176 | 70 | 15632 | 1249 |
Gpr18,Nfkbia,Ifit1bl1,Rtp4,Ifi214,Col18a1,Ddx60,Fas,Phf11c,Ifi207,Adar,Phf11a,Pilrb2,Lap3,Mndal,Ifit3,P4ha1,Ifi203,Tdrd7,Xaf1,Oas1a,Nfkbib,Plscr1,Ifi211,Isg20,Trim14,Trim21,Ifit3b,Dnajb4,Phf11d,Ifi204,Oasl1,Hsd17b7,Cflar,Oas3,Ifi205,Ifi209,Abcc5,Apobec3,Ifi213,Phf11b,Ifit2,Rsad2,Slc15a3,Ifi44,Trim12c,Isg15,Ifih1,Ddx58,Stat2,Usp18,Pml,Malt1,Myd88,Irf7,Ccl5,Ifit1bl2,Oas2,Parp12,Uba7,Ifi208,Ext1,Cxcl10,St7,Oas1g,Herc6,Sp110,Tnfsf10,Thbs1,Pilrb1 |
| 9.786e-32 | -71.40 | GSE42021_TREG_PLN_VS_CD24LO_TREG_THYMUS_DN | MSigDB lists | GSE42021_TREG_PLN_VS_CD24LO_TREG_THYMUS_DN | 191 | 73 | 15632 | 1249 |
Ifi214,Pgs1,Ddx60,Ifi207,Samhd1,Tap1,Phf11c,Adar,Phf11a,H2-Q4,Ifit1bl1,Eif2ak2,Nr4a1,Phf11d,Ifi204,Ifit3b,Ifi35,Stat1,Oasl1,C3,Ifit3,Lap3,Mndal,Ogfr,Psmb8,P4ha1,Rnf31,Oas1a,Tdrd7,Ifi203,Isg20,Trim21,Trim14,Ifi211,Plscr1,Psme2,Zfp36,Usp18,Ddx58,Isg15,Ifih1,Trim12c,H2-Q7,Psme1,Pml,Cd38,Plagl2,Myd88,Psmb9,H2-Q6,Ifi209,Oas3,Ifi205,Phf11b,Ifi213,Apobec3,Tapbp,C1ra,Ifi44,Herc6,Oas1g,Sp110,Il1rn,Tap2,Irf7,Ifit1bl2,Parp12,Oas2,Ube2l6,Ext1,Ifi208,Nmi,Noc4l |
| 1.414e-31 | -71.03 | GSE14000_UNSTIM_VS_16H_LPS_DC_DN | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_DN | 177 | 70 | 15632 | 1249 |
Stard5,Cnot4,Parp9,Gramd1a,Gadd45b,Nfkbia,Trip10,Pim3,Il15,Adar,Slamf7,Nfkbiz,Etv3,Trim21,St3gal5,Oas1a,Dcp1a,Tdrd7,Ppp1r15b,Irf8,Whamm,Cflar,Adam19,Tnfaip2,Hsd17b7,Ifi35,Casp7,Ebi3,Hmgcs1,Dram1,Ell2,Aida,Gpd2,Acsl1,Ifi44,Batf2,Cdyl2,Mecp2,Dhx58,Stat5a,Usp53,Tpst1,Plagl2,Psme1,Irf2,Pml,Prrg4,Rhoh,Ifih1,Dtx3l,Traf1,Trim26,Phlpp2,Parp12,Tbc1d13,4930523C07Rik,Slc31a2,Nampt,Gch1,Cnp,Cd86,Cd274,Irf7,Tnfsf10,Cmpk2,Ldha,Oas1g,Traf3ip2,Ripk2,Pim1 |
| 1.925e-31 | -70.72 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_UP | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_UP | 168 | 68 | 15632 | 1249 |
Usp12,Stat4,Met,Akt3,Procr,Pdss1,Il10,P2ry2,Rabgef1,Nfkb1,Dcun1d3,Agpat4,Adam19,Tnip3,Acvr1b,Acsl1,Ier3,Socs3,Ell2,Kcnj2,Il6,Mrpl52,Ets2,Trip10,Plac8,Gramd1a,Gadd45b,Trim36,Flt1,Nfkbia,Bcl2a1b,Enpp4,Pfkfb3,Fpr2,Eya4,Tmeff1,Tnfsf15,Cd274,Osm,Acsl5,Bcl2a1a,Cxcl1,Clic4,Plat,Osgin2,Ak4,Ptgs2,Pim1,St3gal1,Zc3h12a,Traf3ip2,Bcl2a1d,Rab21,Stat3,Itgb8,Ubtd2,Cish,Ehd1,Tnf,Slc25a37,Irak3,Myo10,Sav1,Batf,Upp1,Il1a,Socs1,Mcoln2 |
| 2.370e-31 | -70.52 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_DN | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_DN | 145 | 63 | 15632 | 1249 |
Ifih1,Ddx58,Csrnp1,Aim2,Ier2,Gbp2,Ncoa7,Cd38,Myd88,Oas3,Otud1,Ifit2,Phf11b,Dhx58,Rsad2,Batf2,Ifi44,Sat1,Cxcl10,Map3k8,Usp42,Ptgs2,Ripk2,Oas1g,Atp10a,Herc6,Tfec,Trafd1,Cmpk2,Epsti1,Tnfsf10,Irak2,Irf7,Cd274,Cnp,Tap2,Ppm1k,Ccl5,Ifit1bl2,Pde4b,Trim26,Nfkbiz,Ddx60,Phf11c,Slamf7,Zbp1,Phf11a,Pnpt1,Il15,D16Ertd472e,Gadd45b,Ifit1bl1,Samd9l,Peli1,Parp14,Irf1,Phf11d,Oasl1,Stat1,Xaf1,Oas1a,Rictor,Plscr1 |
| 2.980e-31 | -70.29 | GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_DN | 169 | 68 | 15632 | 1249 |
Ifit3,Irf8,Mov10,Adap2,Lap3,Trim14,Plscr1,Psme2,St3gal5,Oas1a,Xaf1,Stat1,Oasl1,Phf11d,Ifit3b,Vrk2,Eif2ak2,Cx3cr1,Plac8,Ifit1bl1,Parp14,Samd9l,I830077J02Rik,Parp9,Ddx60,Rtp4,Il15,Adar,Phf11a,Phf11c,Tap1,Samhd1,Slc31a2,Rgl1,Fcgr4,Ifit1bl2,Gch1,Lcp2,Cnp,Irf7,Ube2l6,Oas2,Parp12,Larp1,Herc6,Oas1g,Cxcl10,Epsti1,Fmnl2,Cmpk2,Ifit2,Phf11b,Oas3,Batf2,Ifi44,Rsad2,Dhx58,Aim2,Parp10,Pml,Ddx58,Kmo,Stat2,Usp18,Trim12c,Isg15,Ifih1,Dtx3l |
| 3.672e-31 | -70.08 | regulation of immune effector process | biological process | GO:0002697 | 414 | 102 | 20694 | 1406 |
Treml4,Pvr,Il18rap,Ptprj,Klrk1,Raet1e,Ptafr,Htra1,Traf2,Parp9,Mul1,Hlx,Ripk2,Gbp4,Dnase1l3,Fgl2,Il18,Tnfrsf1b,Zc3h12a,Zc3hav1,Nlrp3,Stat1,Il12rb1,H2-T22,Tnfaip3,Hmox1,H2-Q4,Tlr2,Ripk3,Ddx58,Tlr9,Slamf8,Fcgr1,Irf1,Ccl2,H60b,H2-Q6,Il10,Tnfsf4,Apobec3,Cxcl1,Stat5a,Aim2,Irak3,Dtx3l,Fzd5,Ddx60,Nectin2,Clec2d,Elmod2,Nfkbid,Nod2,Il15,Tap2,H2-Q7,Spn,H2-M2,Adora2b,Il6,Abr,H2-T24,Ifna1,Lgals9,Tap1,Dhx58,Pik3r6,Il1b,Nfkbiz,Tlr3,H2-T10,Il4ra,Tnfrsf14,Lyn,Clcf1,Nr4a3,Il27,Angpt1,Pml,Fcgr2b,Rasgrp1,Arid5a,Syk,Stxbp1,Rsad2,Tnf,Bcl6,Malt1,Cd55,Cd74,C3,Parp3,Cgas,Traf3ip2,Il12b,Cd40,Ankrd17,Fgr,Ifnb1,Hk1,Serpinb9,Rabgef1,Ccl5 |
| 4.429e-31 | -69.89 | cell surface receptor signaling pathway | biological process | GO:0007166 | 1726 | 247 | 20694 | 1406 |
Cacnb3,Nrp2,Cpeb4,Plek,Casp2,Sema4a,Bmp2,Il6,Itga5,Acvr1b,Il2rg,Lox,Jag1,Mlkl,Pdgfc,Ifna1,Mapkapk2,Isg15,Il1b,Dtx2,Nfkbiz,Tlr3,Plat,Ifnar1,Itgav,Casp3,Ppm1l,Nr4a3,Prkce,Cdk5r1,Ccnd1,Ift57,Ifna6,Nck1,Myd88,Met,Acvrl1,Gpr35,Casp8,Fcgr2b,Ubash3b,Bcl2a1b,Kdr,Kitl,P2ry12,P2ry2,Cx3cl1,Gdf15,Ifitm1,Cd14,Mark2,P2ry13,Il12b,Il1rn,Fut8,Daam1,Calcrl,Notch2,Egr1,Sema3c,Bcl2l11,Stat3,Hck,Src,Bcl2a1a,Peli1,Stat2,Lcn2,Fpr2,Lif,Pdgfb,Klrk1,Ebi3,Ptafr,Cxcl10,Flt1,Itga9,Tnfrsf1b,P2ry14,Rgs14,Crkl,Stat1,Lcp2,Flrt3,Jak2,Il12rb1,Cxcl3,Inhba,Irf7,Nfkbia,Adrb2,Pf4,Fcgr1,Ccl2,Maml2,Scyl2,Ddit4,Tulp3,Vegfc,Mecp2,Ifna2,Socs3,Cenpj,Iigp1,Znrf3,Stat5a,Cxcl1,Ccl7,Socs1,Ccl8,Myc,Fcgr4,Dcp1a,Pdgfrb,Ptpn2,Fzd5,Ptk2,Tle3,Ccl9,Spen,Rhoq,Csf3r,Ccrl2,Csrnp1,Sipa1l1,Hcar2,Il15,Csf1,Dennd1b,Spn,Pik3cd,Cd38,Rapgef2,Stoml1,Adgrl2,Adora2b,Cd86,Klf6,Cd80,Acsl1,Fos,Bcl2a1d,Bcl9,Arf4,Ccl22,Sirt1,Axl,Hp,Il15ra,Cd274,Hhex,Ptch1,Il4ra,Kremen1,Osm,Lyn,Cav1,Clcf1,Cxcl11,Sdc1,Col4a2,Angpt1,Pml,Ccr1,Zyx,Caml,Ccl12,Syk,Cited2,Stat4,Ccl4,Bambi,Fzd1,Jun,Ccl3,Il1a,Tnf,Arid5b,Oas2,Pde4b,Rnf31,Fpr1,Malt1,C3,Cd74,Il13ra1,Igf1r,Cd40,Fgr,Mtdh,Phip,Irs2,Jmjd6,Ifnb1,Ccl5,Cxcl2,Gcnt2,Dyrk2,Icosl,Ccne1,Hap1,Il18rap,Ptprj,Nmi,Cxcl9,Ifna5,Traf2,Ifna4,Lrp4,Ripk2,Mvp,Cd300lf,Irak2,Tiparp,Il18,Zc3h12a,Itgal,Notch1,Adgre4,Themis2,Tlr2,Clec4d,Clec4e,Irf1,Adgrg6,Cx3cr1,Plaur,Acvr1,Plpp3,Cmklr1,Adora2a,Aim2,Dtx3l,Irak3,Itga4,Lnpep,Ccr3,Itgb8,Socs7,Sema4c,Homer1,Stap1,Edn1,Flrt2,Nfkbid,Fas,Lrp8 |
| 6.574e-31 | -69.50 | cellular response to interferon-beta | biological process | GO:0035458 | 45 | 34 | 20694 | 1406 |
Tgtp2,Mndal,Gm4841,Ifi211,Ifi214,Ifi47,Gm12185,Ifnb1,Igtp,Ifi209,Ifi205,Tgtp1,Acod1,Stat1,F830016B08Rik,Ifi207,Ifi203,Ifit3,Gbp3,Gbp2,Irgm1,Irf1,Ifi208,Irgm2,Aim2,Pnpt1,Ifi213,Ifi204,Gm4951,9930111J21Rik1,Gm5431,Iigp1,Gbp2b,Ifit1 |
| 9.372e-31 | -69.14 | GO_RESPONSE_TO_VIRUS | MSigDB lists | GO_RESPONSE_TO_VIRUS | 223 | 78 | 15632 | 1249 |
Il6,Bnip3,Ifna5,Ifnb1,Bcl2l11,Ifit1bl1,Nlrc5,Eif2ak2,Hmga1,Adar,Ifna1,Samhd1,Zc3hav1,Ifi207,Ddx60,Nlrp3,Ifi214,Ccl22,Plscr1,Isg20,Ifi211,Ifi203,Trim56,Oas1a,Ikbkg,Mndal,Ifit3,Ccl4,Gbp2b,Oasl1,Stat1,Pim2,Tnfsf4,Ifit3b,Fam111a,Ifi204,Odc1,Irf1,Ifi44,Rsad2,Dhx58,Apobec3,Ifnar1,Tnf,Src,Ifit2,Ifi213,Cd40,Ifi209,Eno1,Oas3,Ifi205,Psmb9,Ifna2,Irak3,Ifit1,Pml,Isg15,Ifih1,Fgr,Trim12c,Stat2,Ddx58,Ifi208,Ifna6,Ddit4,Oas2,Ccl5,Ifit1bl2,Irf7,Cd86,Ikbke,Elmod2,Oas1g,Zc3h12a,Tlr3,Il12b,Cxcl10 |
| 9.495e-31 | -69.13 | PHONG_TNF_RESPONSE_NOT_VIA_P38 | MSigDB lists | PHONG_TNF_RESPONSE_NOT_VIA_P38 | 320 | 95 | 15632 | 1249 |
Optn,Vcan,Phactr4,Mid1,Sod2,Bcl2a1b,Ets2,Trip10,Sdc4,Phf11a,Klf7,Slc30a1,Cx3cl1,Irs2,Trim21,Csf1,Mmd,Nfkb1,Tnfrsf1b,Gem,Ldlr,Dram1,Mmp9,Trib1,Klf6,P4ha2,Slc25a37,Phf11b,Plekha5,Mtus1,H2-Q6,Rhbdf2,Rgs3,Nrp2,Rapgef2,Sh3bp4,Parp12,Fzd5,Serpine1,Map2k1,Vcam1,Nfkb2,Ikbke,Ptges,Ripk2,Rcan1,Trib3,Arid5b,Peli1,Rai14,H2-Q4,Hivep2,Nfkbia,Rhof,Dock4,Jun,Plau,Phf11c,Abr,Ampd3,Abtb2,Birc3,Ogfr,Cflar,Tnip1,Tnfaip2,Phf11d,Irf1,Pik3cd,Slc25a22,Dusp8,Bcl2a1d,Ehd1,Dse,Psmb9,Tank,Cd83,Relb,Gbp2,Ier2,H2-Q7,Irf2,Icam1,Slco3a1,Traf1,Nmi,Slc2a6,Gch1,Bcl2a1a,Bambi,Plaur,Rnf19b,Smox,Grina,Cxcl10 |
| 1.124e-30 | -68.96 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_DN | 182 | 70 | 15632 | 1249 |
Rgl1,Vps54,Irf7,Lcp2,Stxbp3,Ext1,Spint2,G3bp2,Bst1,Fndc3a,Dnaja2,Smc5,Traf3ip2,St3gal1,Il12b,Tnfsf10,Mitd1,Plcl2,Sp110,Plekhf2,Tcf4,Gpsm2,Rbbp8,Batf2,Rab9,Fut8,Hdac1,Aebp2,Glipr2,Hhex,Magohb,Slco3a1,Cutc,Sav1,Cd83,Bfar,Rnf34,Mvp,Prpf38a,Mdfic,Apaf1,Ppp1r15b,Adap2,Gna15,Rel,Zfp36,Csf1,Bcl9,Met,Rasgrp1,Kctd12,Mtmr14,Rgs1,Asf1a,Wdr43,Klf3,Nat2,Peli1,Dusp2,Katna1,Triobp,Stxbp1,Ccnd2,Tspo,Slamf7,Sgcb,Hinfp,Slc25a25,Slc28a2,Atp11b |
| 1.162e-30 | -68.93 | positive regulation of response to biotic stimulus | biological process | GO:0002833 | 214 | 71 | 20694 | 1406 |
Aim2,Tnf,Ifi204,Rsad2,Stat5a,Cxcl1,Nlrc5,Rasgrp1,H60b,Irgm1,Myd88,Nfkbia,Tlr9,Tnip3,Nod2,Nod1,Ankrd17,Ifih1,Il12b,Cgas,Tlr1,Nr1h3,Nectin2,Cd74,Cd180,Ddx60,Cd14,Irak3,Ifi214,Ikbke,Wdfy1,Tifa,Parp9,Ripk2,Ifi208,Irgm2,Raet1e,Klrk1,Trim12c,Cd86,Il18rap,Fpr2,Pvr,Ifi203,Peli1,Plscr1,Treml4,Ddx58,Ifi209,Clec4e,Prkce,Tlr2,Irf7,Cav1,Tnip1,Acod1,Tlr6,Nlrc4,Ifi205,Zbp1,Tlr3,Mndal,Dhx58,Cd274,Zc3hav1,Lgals9,Mapkapk2,Irak2,Optn,Cd300lf,Ifi211 |
| 1.176e-30 | -68.92 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_UP | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_UP | 153 | 64 | 15632 | 1249 |
Slamf7,Pfkfb3,Plau,Slfn5,Nfkbiz,Irs2,Fpr2,Aftph,Il6,Ift57,Sod2,Sqstm1,Eif2ak2,Cnn2,Gramd1a,Tmem184b,Zcchc2,Dusp16,Pim2,Socs3,Oasl1,Lyn,Tnip3,Ampd3,S100a8,Lcn2,Tnfsf14,Smg7,Tnfrsf8,Tnfaip3,Plagl2,Irak3,Etv5,Mxd1,Tab2,Ubtd2,Ifi44,Cebpd,Rsad2,Mdm2,Stat5a,Bcl6,Dse,Thbs1,Cxcl1,Snapc1,Ptges,Il1b,Traf3ip2,Ptger4,Ptprj,Nsmaf,Map3k8,Fpr1,Rcan1,Slc43a3,Scn1b,Gpr132,AA467197,Cxcl2,Hk2,Map4k4,Osm,Samsn1 |
| 1.543e-30 | -68.64 | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | 1052 | 195 | 15632 | 1249 |
Nr4a1,Ass1,Dnaja1,Tmem184b,D16Ertd472e,Rin2,Ddx60,Col18a1,Sdc1,Ifi214,Slc30a1,Il15,Ifi207,Mndal,Slc9a1,Trim21,Csf1,Mmd,Kctd12,Dram1,Cdkn1a,Cycs,Phgdh,Ifi44,Nfkbie,Mafk,Rsad2,Dhx58,Usp18,Upp1,Cd14,Slc12a9,Gdf15,Dusp6,Col11a2,Ppp1r15a,Plekha4,Fosb,Atp6v1d,Pdlim7,Vasn,Tlr3,Crkl,Rcan1,Sp110,Cenpe,Fam43a,Ccl12,Tiparp,Mapkapk2,Il4ra,Eno2,Gna15,Zc3h12c,Gbp7,Mafg,Acsl1,Tlr2,Slc25a22,Sh3bgrl2,Ifi213,Psmb9,Klhl25,Ifi205,Pde1b,Ccdc86,Top3a,Carhsp1,Ube2e1,Pml,Daxx,Ifit1bl2,Junb,Tuba4a,Gch1,Btg2,Ifi208,Nmi,Scn1b,Uba7,Hap1,Dgka,Cd55,Smox,Cmpk2,Spsb1,Cited2,Hmga1,Ggct,Fas,Cx3cl1,Rtp4,Cdk5r1,Ahr,Tor3a,Rnf14,Lmo4,Isg20,Srxn1,Pstpip2,Ifi211,Zfp36,Alas1,Cpeb4,Oasl1,Ifi204,Ifit3b,Lhx2,Dnajb2,Ankrd17,Ifi209,Oas3,Slc39a4,Ogfrl1,Plk3,F11r,Zfp281,Rnf135,Ifih1,Myd88,1600014C10Rik,Ube2f,Apaf1,Stau1,Fzd5,Higd1a,Cd274,Irf7,Sap30,Snx2,Parp12,Hmox1,Slc31a1,Il18,Cxcl1,Gcnt2,Cldnd1,Ikbke,Plat,Ifit1bl1,Bcl2l11,Fos,Irgm2,Stard5,Tra2a,Atf3,Egr1,Slc25a25,Pnpt1,Zbp1,Rbm43,Tap1,Rabgef1,Ltbp2,Ifit3,Procr,Sirt1,Ifi203,Ifi35,Endod1,Ppa1,Denr,Stat1,Adrb2,Src,Ehd1,Hspa1a,Tbc1d1,Egr2,Pnp2,Mdm2,Kdm5b,Tapbp,Marcksl1,Lif,Mthfr,Stat2,Isg15,Mapkbp1,Rgl1,Plk2,Asah2,Igsf8,Inpp5b,Pdgfb,Csf3,Oas2,Rnf19b,Ptger4,Ak4,Grina,Ttc39b,Cxcl10,Thbs1,Trafd1 |
| 1.904e-30 | -68.43 | GO_IMMUNE_EFFECTOR_PROCESS | MSigDB lists | GO_IMMUNE_EFFECTOR_PROCESS | 404 | 108 | 15632 | 1249 |
Zc3hav1,Ifi207,Clec4e,Slamf7,Ifi214,Nck1,Fas,Ddx60,Ifna5,Ifnb1,Ctsc,Bnip3,Syk,Eif2ak2,Gbp2b,Notch2,Lyn,Ifit3b,Ifi204,Oasl1,C3,Ptk2,Pou2f2,Trim56,Isg20,Ifi211,Mndal,Ifna2,Batf,Ifih1,Cd74,Rsad2,Dhx58,Ifi209,Oas3,Ifit2,Nr4a3,Tlr3,Stxbp3,Ddit4,Irf7,H2-Eb1,Samhd1,Fcgr1,Adar,Prdx1,Ifna1,Il4ra,Nlrp3,Il6,Prkce,Irf4,Cyfip1,Cx3cr1,Nlrc5,Ifit1bl1,Trem1,Actb,Pik3cd,Fam111a,Sema4a,Irf1,Stat1,Rasgrp1,Ifi203,Jag1,Oas1a,Plscr1,C1rl,Ifit3,Itgal,Relb,Myo10,Hck,Ifit1,Isg15,Trim12c,Fgr,Stat2,Cd180,Ddx58,Icam1,Pml,C1ra,Dennd1b,Cd40,Ifi205,Swap70,Apobec3,Ifnar1,Src,Ifi213,Elmod2,Plcl2,Serpinb9,Il12b,Clec4d,Cxcl10,Oas1g,Zc3h12a,Cd55,H2-Ab1,Ptger4,Oas2,Ifi208,Ifna6,Cd86,Ifit1bl2 |
| 2.449e-30 | -68.18 | GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN | 189 | 71 | 15632 | 1249 |
Max,Etnk1,Mtmr14,Tmod3,Stat1,Jak2,Vrk2,Hsd17b7,Ednrb,Casp8,Csf1,Akt3,Trim14,Flnb,Psme2,Oas1a,Trim56,Hat1,Atf3,Mapkapk2,Ccnd2,Spred1,Ppfibp1,Angpt1,Bcl2a1b,Slfn8,Abcb1a,Il4i1,Cd200r4,Optn,Cpd,Tlr3,Oas1g,Bcl2a1a,Slfn9,Pkp4,5430427O19Rik,Csrp1,Ccl5,Cd86,Fzd5,Sipa1l1,Vps54,Inpp5b,Sap30,Stxbp3,Slc2a6,Wars,Marcksl1,Psme1,Irf2,Prdm1,Prrg4,Pml,Icam1,Cutc,Cd38,Hck,Mvp,Axl,Tnf,Traf2,Tbc1d1,Setdb2,Cish,Mecp2,Hdac1,Fgl2,Cers6,Bcl2a1d,Tapbp |
| 2.643e-30 | -68.11 | positive regulation of multi-organism process | biological process | GO:0043902 | 345 | 91 | 20694 | 1406 |
Plat,Ifi205,Tlr3,Acod1,Cav1,Pcx,Tnip1,Ifi209,Trim30a,Prkce,Lgals9,Mapkapk2,Dhx58,Acvr1b,Plscr1,Cd86,Ankrd17,Larp1,Nod1,Tnip3,Ifi214,Ednrb,Cd14,Cd74,Cd180,Cgas,Il12b,Tlr1,Nlrc5,Jun,Rsad2,Tnf,Ifi204,P2ry2,Mdfic,Irgm1,Myd88,Rasgrp1,Zbp1,Tlr6,Nlrc4,Irf7,Inhba,Clec4e,Adar,Ddx58,Tlr2,Ifi211,Optn,Cd300lf,Irak2,Il18,Zc3hav1,Chmp4b,Mndal,Notch1,Klrk1,Raet1e,Ptafr,Parp9,Ripk2,Ifi208,Tifa,Irgm2,Nos2,Ikbke,Wdfy1,Treml4,Peli1,Bcl2l11,Fpr2,Ifi203,Pvr,Trim12c,Il18rap,Stau1,Ifih1,Trim21,Nod2,Pde5a,Irak3,Ddx60,Nr1h3,Nectin2,Cxcl1,Stat5a,Aim2,Tlr9,Nfkbia,Plau,H60b |
| 2.671e-30 | -68.10 | QI_PLASMACYTOMA_UP | MSigDB lists | QI_PLASMACYTOMA_UP | 248 | 82 | 15632 | 1249 |
Ubash3b,Il4ra,Nr1h3,Fas,Tnfrsf14,Dnase1l3,Ciita,Rras2,Clec4e,Gng11,Zyx,Nfkbia,Plac8,Cnn2,Il18bp,Irgm2,Stap1,Dusp2,Irf1,Sema4a,Casp7,Ifi35,Tlr9,Tmod3,Fscn1,Cd82,Rgs1,Tnfaip2,Hcls1,Ccl4,Marco,Irf8,Gna15,Casp4,Psmb8,Il18rap,Trim21,Plscr1,Traf1,Socs1,Fgr,Irf2,Apaf1,Hck,Myo10,Tnfaip3,Relb,Batf,Gnb4,Sla,Swap70,Psmb9,Cd40,Axl,Ehd1,Tnf,Casp1,Cst7,Nfkbie,Fgl2,Rsad2,Casp3,Cish,Slc43a3,Il2rg,Il18,Ptges,Pf4,Dek,Plcl2,Cnp,Plek,Ccr1,Rgl1,Snx10,Ccl5,Snx2,Vasp,Icosl,Pdgfb,Pdlim7,Tlr1 |
| 3.499e-30 | -67.83 | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | 165 | 66 | 15632 | 1249 |
Myd88,Agtrap,Dtx3l,Isg15,Ddx58,Stat2,Usp18,Psme1,H2-Q7,Rsad2,Tapbp,Tlk2,Ifi205,Oas3,Ifi209,H2-Q6,Ifi213,Ifit2,Phf11b,Cmpk2,Sp110,Oas1g,Tlr3,Herc6,Parp12,Ifi208,Irf7,Ppm1k,Tap2,Ifit1bl2,Phf11c,Ifi207,Adar,Phf11a,Pnpt1,Xrn1,Ifi214,Ddx60,Samd9l,Parp9,Optn,Parp14,Dnaja1,Eif2ak2,Ifit1bl1,Nlrc5,H2-Q4,Ifit3b,Phf11d,Ifi204,Stat1,Oasl1,Ifi35,Tdrd7,Ifi203,Oas1a,Psme2,Plscr1,Ifi211,Trim14,Trim21,Lap3,Mndal,Ifit3,Mov10,Atm |
| 3.519e-30 | -67.82 | DER_IFN_ALPHA_RESPONSE_UP | MSigDB lists | DER_IFN_ALPHA_RESPONSE_UP | 87 | 48 | 15632 | 1249 |
Plod2,Mndal,Casp8,Ifit3,Psmb8,Ifi203,Oas1a,Plscr1,Trim14,Trim21,Ifi211,Ifit3b,Ifi204,Irf1,Oasl1,Stat1,Ifi35,H2-Q4,Ifit1bl1,Il6,Ifi214,Fas,Tap1,Ifi207,Adar,Ifit1bl2,Oas2,Ifi208,Nmi,Trim26,Oas1g,Sp110,Vegfc,Ifi209,Ifi205,Psmb9,H2-Q6,Ifi213,Ifi44,Cycs,Isg15,Psmb10,Pml,Irf2,H2-Q7,Psme1,Rhoc,Cd164 |
| 3.738e-30 | -67.76 | GSE10325_MYELOID_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_MYELOID_VS_LUPUS_MYELOID_DN | 185 | 70 | 15632 | 1249 |
Ldlr,Zcchc2,Vrk2,Oasl1,Stat1,Ifi35,Casp7,Acsl1,Ifit3b,Ifi204,Plscr1,Psme2,Pdss1,Ifi211,Xaf1,Ifi203,Lap3,Mndal,Ifit3,Marco,Adar,Tap1,Ifi207,Ddx60,Ifi214,Rtp4,Pdpn,Igsf6,Chst11,Ccl12,Ifit1bl1,H2-Q4,Eif2ak2,Il1rn,Gtpbp2,Acp2,Tfec,Il15ra,Herc6,Atp10a,Cxcl10,Pim1,Grina,Ifi208,Nmi,Ube2l6,Parp12,Rgl1,Ifit1bl2,Plek,Txn1,Irf7,Hlx,H2-Q7,Ifih1,Isg15,Usp18,Upp1,Kmo,Ifi44,Stat3,Rsad2,Psma6,Dhx58,Ifi213,Slc25a37,Ifit2,Ifi209,Ifi205,H2-Q6 |
| 3.794e-30 | -67.74 | GSE42724_MEMORY_BCELL_VS_PLASMABLAST_UP | MSigDB lists | GSE42724_MEMORY_BCELL_VS_PLASMABLAST_UP | 180 | 69 | 15632 | 1249 |
Prdm1,Csrnp1,Pml,Icam1,Atp11a,Stat2,Usp18,Apaf1,Gypc,Ppp6r1,Insl6,Traf2,Rab21,Rab9,Rnf24,Ogfrl1,Dhx58,Rnf19b,Pcgf5,Serpinb9,Il1rn,Clic4,Il15ra,Cmpk2,4930523C07Rik,Cdyl,Gch1,Cd274,Samsn1,Tap2,Ppm1k,Irf7,Vps54,Inpp5b,Stoml1,Oas2,Uba7,Ddx60,Lrp8,Etv3,Prnp,Nxf1,Il4ra,Il15,Dusp14,Slfn5,Spsb1,Psip1,Tspan3,Zyx,Parp14,Il4i1,Il6,Etnk1,Stat1,Cacnb3,Cflar,Arf4,Ldlr,Dusp16,Hsd17b7,Eno2,Ppp1r15b,Nfkb1,Rel,Htra1,Plscr1,Stat4,Hat1 |
| 5.035e-30 | -67.46 | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | 161 | 65 | 15632 | 1249 |
Ptger4,Ripk2,Zc3h12a,Dusp5,Pim1,Ptgs2,Osgin2,Nsmaf,Map3k8,Il18,Cxcl1,Snapc1,Plaur,Txn1,Cd274,Ddit4,Arl5b,Tnfsf15,Inhba,Csf3,Rapgef2,Plk3,Csrnp1,Il1a,St3gal6,Sav1,Dusp1,Tnf,Klf6,Usp53,Homer1,Rbbp8,Rab21,Errfi1,Mafk,Socs3,Dnajb4,Ier3,Clcf1,Cflar,Rgs1,Cdkn1a,Rabgef1,Ppp1r15b,Il10,Gem,Srxn1,Csf1,Ccrl2,Usp12,Egln3,Nfkbiz,Egr1,Nlrp3,Pim3,Gadd45b,Nr4a1,Flt1,Ets2,Jun,Edn1,Spry2,Gclm,Dusp2,Il6 |
| 7.573e-30 | -67.05 | GO_DEFENSE_RESPONSE_TO_VIRUS | MSigDB lists | GO_DEFENSE_RESPONSE_TO_VIRUS | 143 | 61 | 15632 | 1249 |
Ifit1bl2,Cd86,Irf7,Ddit4,Ifna6,Ifi208,Oas2,Tlr3,Zc3h12a,Oas1g,Il12b,Cxcl10,Elmod2,Ifit2,Ifi213,Ifnar1,Apobec3,Oas3,Ifi205,Cd40,Ifi209,Dhx58,Rsad2,Pml,Ddx58,Stat2,Trim12c,Isg15,Ifih1,Ifit1,Ifna2,Ifit3,Mndal,Ifi211,Isg20,Plscr1,Oas1a,Trim56,Ifi203,Stat1,Oasl1,Irf1,Ifi204,Fam111a,Ifit3b,Gbp2b,Eif2ak2,Ifit1bl1,Nlrc5,Bnip3,Il6,Ifna5,Ifnb1,Ddx60,Ifi214,Nlrp3,Ifna1,Adar,Ifi207,Zc3hav1,Samhd1 |
| 8.196e-30 | -66.97 | GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_UP | 187 | 70 | 15632 | 1249 |
Gbp2,Tnfaip3,Ube2f,Socs1,Slco3a1,Zfp281,Upp1,Nfkbil1,Atp13a1,Tlk2,Dbnl,Rab9,1110038F14Rik,Tcf4,P2ry12,Rgs14,Psmb9,Plod3,Plekha5,Parp8,Tcea1,Serpinb2,Plat,Prkx,Clic4,Plcl2,Slfn3,Il2rg,Dgka,Btg2,Atp6v1d,Slfn4,Ppp1r15a,Ccnj,Slc7a8,Tnks1bp1,Cd80,F10,Sdc4,Rbms2,Hinfp,Tlr6,Atf3,Triobp,Cnot4,4932438A13Rik,Abcb1a,Ptpn2,Dnaja1,Rnf114,Psip1,Crbn,Morc3,Nlgn2,Plekhn1,Kdr,Polr2g,Arf4,Pik3cd,Hat1,Sirt1,Csf1,Ociad1,Ogfr,Casp4,Plod2,Mov10,Hk1,Tor3a,Psat1 |
| 8.448e-30 | -66.94 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_45MIN_DN | 182 | 69 | 15632 | 1249 |
Fpr1,Cxcl10,Il12b,Nr4a3,Chic2,Clic4,Ralgds,Pf4,Ppp2r2a,Sp110,Il1b,4930523C07Rik,Sipa1l1,Osm,Cd274,Slc2a6,Inpp5b,Psme1,Gbp2,Tnfaip3,Ifit1,Pdgfc,Insl6,Ifit2,Cd40,Tank,Psmb9,Cp,1110038F14Rik,Dhx58,B3gnt5,Gsr,Treml2,Arhgap26,Ifi35,Acsl1,Sema4a,Ifit3b,Rgs1,Jak2,Gfi1,S100a8,Lmo4,Ifit3,Nfkbib,Alas1,Xaf1,Rap1gap2,Slamf9,Ccrl2,Cdkn2d,Arrdc4,Fcgr1,Zbp1,Ciita,Angpt1,Slc28a2,Samhd1,Sod2,Slc7a11,Msr1,Gpr18,Ppp2r5a,Dusp2,Irgm2,Triobp,Gadd45g,Samd9l,Cox17 |
| 8.470e-30 | -66.94 | GSE40685_TREG_VS_FOXP3_KO_TREG_PRECURSOR_UP | MSigDB lists | GSE40685_TREG_VS_FOXP3_KO_TREG_PRECURSOR_UP | 172 | 67 | 15632 | 1249 |
Psmb8,Nos2,Casp4,Ifit3,Mov10,Psme2,Trim21,Xaf1,Oasl1,Stat1,Max,Kpna3,Casp7,Ifi35,Ifit3b,Mefv,Rcsd1,Irf1,Jak2,Rnf114,Nlrc5,H2-Q4,Znfx1,Parp14,Samd9l,Parp9,Usp25,Ddx60,Rtp4,Xrn1,Adar,Tap1,Hk3,Gch1,Slc31a2,Nampt,Snx10,Nmi,Ube2l6,Wdfy1,Oas2,Parp12,Rapgef2,Rnf19b,Fpr1,Pim1,Tnfsf10,Pgk1,Ppp2r2a,Trafd1,Sp110,Epsti1,Casp1,Ifit2,H2-Q6,Psmb9,Batf2,Stat3,Tapbp,Rsad2,Psme1,H2-Q7,Aim2,Gbp3,Socs1,Stat2,Gbp2 |
| 8.470e-30 | -66.94 | GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP | MSigDB lists | GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP | 172 | 67 | 15632 | 1249 |
Smox,Ptger4,Fndc3a,Grina,Serpinb9,Cxcl10,Clic4,Bambi,Trafd1,Glrx,Pde4b,Brd2,Dusp6,Ppp1r15a,Cd86,Cd274,Sipa1l1,Irf7,Ube2l6,Gpr132,Phlda1,Slc7a5,Arl5b,Mxd1,Malt1,Plk3,Usp18,Hif1a,Tnf,Arid5a,Oas3,Stat3,Casp3,Ifi44,Cish,Fgl2,Rsad2,Dhx58,Socs3,Stat1,Dnajb4,Znrf1,Zcchc2,Ccl4,Idi1,Adam19,Rgs1,Dusp16,Nfil3,Tnfrsf1b,Gem,Isg20,Zfp36,Sirt1,Atf3,Abr,St3gal3,Egr1,Prnp,Zbp1,Nfkbia,Trim36,Gadd45b,Jun,Ets2,Tmem184b,Dusp2 |
| 8.470e-30 | -66.94 | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_DN | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_DN | 172 | 67 | 15632 | 1249 |
Trem1,Tnip1,Ccl4,Acvr1b,Tnip3,Tlr2,Lyn,Acsl1,Met,Plscr1,Gna15,P2ry2,Dcun1d3,Pfkfb3,Cdc42ep2,Clec4e,Etv3,Fpr2,Nfkbiz,Cdkn2d,Cpd,Il6,Trip10,Plac8,Slc7a11,Sod2,Bcl2a1b,Il15ra,Plaur,Ptges,Glrx,Acp2,Cxcl1,Bcl2a1a,Nfkb2,Ak4,Ptgs2,Zc3h12a,Traf3ip2,Ldha,AA467197,Cxcl2,Ddit4,Pdlim7,Cd274,Samsn1,Nampt,Gch1,Etv5,Zfp319,Tnfaip3,Hck,Plagl2,Batf,Icam1,Traf1,Socs1,Hlx,Mcoln2,Gpr68,Bcl2a1d,Fut8,Cish,Itgb8,Bcl6,Slc25a37,N4bp1 |
| 8.839e-30 | -66.90 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | 498 | 121 | 15632 | 1249 |
Birc3,Ubr4,St3gal5,Procr,Eef1e1,Met,Casp2,Rasgrp1,Mtmr14,Rgs1,Trem1,Slc7a11,Zyx,Rhof,Jun,Pdpn,Ccl2,Il6,Slc44a1,Rai14,Igsf6,Gpr35,Edn1,Irf4,Nqo1,Sdc2,Lrp8,Etv3,Ccl22,Plau,Slc7a8,Phlda1,Btg2,Maff,Fndc3a,Cd55,Smox,Ak4,Slamf8,Mob3b,Serpinb2,Il1rn,Acsl5,Plaur,Fmnl2,Cst7,Src,Cd40,Itpr1,Rhoq,Pnp2,Dennd1b,Minpp1,Gsr,Rhoh,Marcksl1,St3gal6,Traf1,Agtrap,Il1a,Rhoc,Crim1,Dcun1d3,Rel,Srxn1,Csf1,C3,Mthfd2,Lpar1,Adam19,Fscn1,Polr2g,Fam102b,Abcc1,Lrrc8c,Fam162a,Ets2,Mrpl52,Fcgr2b,Gadd45g,Dusp4,Scarf1,Nek6,Ciapin1,Pgm1,Olr1,Dnase1l3,Csrp1,Dusp6,Ttc9c,Cdyl,Rrs1,Hopx,Pdlim7,Cxcl2,Tbc1d13,Vasp,Inhba,Rtn1,St7,Il2rg,Nr4a3,Cox18,Rcan1,Plat,Cxcl1,Il1b,Plekha5,Txnrd1,P4ha2,Tcf4,Rab11fip1,Tnc,B3gnt5,Cers6,Ccng2,Gpr68,Nfkbie,Plk3,Fabp3,Pdgfc |
| 1.003e-29 | -66.77 | regulation of leukocyte activation | biological process | GO:0002694 | 521 | 114 | 20694 | 1406 |
Il2rg,Abr,Atm,Il6,Cd80,Adora2b,Ctsc,Cd86,Cd38,Thbs1,Hsph1,Spn,Tnfsf9,Prnp,Plscr1,Cav1,Lyn,Tnfrsf14,Il4ra,Tnfsf14,Ahr,Nr4a3,Clcf1,Nfkbiz,Casp3,Lgals9,Il15ra,Axl,Pik3r6,Il1b,Cd83,Cd274,Slc7a2,Cx3cl1,H2-Aa,Syk,Stxbp1,Cdkn1a,Rasgrp1,Sdc4,Fcgr2b,Milr1,Nck1,Prdm1,Il27,Myd88,Ikzf1,Irs2,Ifnb1,Ccl5,Rabgef1,Fgr,Cd40,Vcam1,Ccdc88b,Cst7,Parp3,Cd74,Il12b,Cgas,Bcl6,Samsn1,Malt1,Ripk2,Hlx,Klrk1,Arg2,Ptafr,Ldlr,Peli1,Egr3,H2-Ab1,Icosl,Tnfaip3,Il12rb1,Tarm1,Cd200,Ripk3,Clec4d,Hmox1,Sphk1,Tlr6,Nlrp3,Cd300lf,Itgal,Zc3h12a,Tnfrsf1b,Slamf7,Il18,Fgl2,Stat5a,Ap3b1,Socs1,Slfn1,Adora2a,Bst1,Il10,Tnfsf4,Slamf8,Tlr9,Irf1,Ccl2,Nod2,Nfkbid,Fas,Il15,Stap1,Mmp14,Zeb1,Nr1h3,Nectin2,Pde5a,Ptpn2,Ctla2a |
| 1.215e-29 | -66.58 | GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_UP | 144 | 61 | 15632 | 1249 |
Ccl5,Lcp2,Asah2,Mmp13,Hap1,Atp10a,Tlr3,Osgin2,Gpr85,Cxcl10,Nr4a3,Ttc39b,Rsbn1,Gca,Dcbld2,Fmnl2,Zhx2,Sp110,Arhgef3,Ttc39c,Psmb9,Itgb8,Kdm5b,Rsad2,Magohb,Psme1,Aim2,Slc30a4,Klf8,Ifih1,Isg15,Gnb4,Crim1,Prpf38a,Gbp2,Ednrb,Rel,Ptch1,Plod2,Bcorl1,Cysltr2,Trim21,Cd69,Rasgrp1,Syne2,Xaf1,Il13ra1,Uaca,Rac3,Rcn1,Lpar1,Polr2g,Kdr,Socs7,Peli1,Il6,Dtnb,Ifnb1,Pttg1,Htr2a,Ahr |
| 1.280e-29 | -66.53 | DER_IFN_BETA_RESPONSE_UP | MSigDB lists | DER_IFN_BETA_RESPONSE_UP | 113 | 54 | 15632 | 1249 |
Sp110,Plaur,Oas1g,Phlda1,Ifi208,Nmi,Trim26,Oas2,Ifit1bl2,Fubp1,Rhoc,Cd164,Psme1,H2-Q7,Irf2,Psmb10,Isg15,Hif1a,Ifi44,Cycs,Cebpd,Ifit2,Ifi213,Ifi209,Ifi205,Psmb9,H2-Q6,Ap3m2,Stat1,Oasl1,Ifi35,Ifit3b,Irf1,Ifi204,Plscr1,Trim21,Trim14,Ifi211,Ifi203,Oas1a,Psmb8,Mndal,Plod2,Casp8,Ifit3,Adar,Tap1,Ifi207,Ifi214,Il6,H2-Q4,Ifit1bl1,Eif2ak2,Ets2 |
| 1.329e-29 | -66.49 | GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP | MSigDB lists | GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP | 135 | 59 | 15632 | 1249 |
Il1a,Lif,Plk3,Ier2,Prdm1,Tnfaip3,Ankrd17,Ddhd1,Dusp1,Hsph1,Cebpd,Egr2,Nr4a3,Il12b,Ptgs2,Rcan1,Dusp5,Ptger4,Shisa3,Kdm6b,Cxcl1,Fosb,Serpine1,Plk2,Dusp6,Gdf15,Junb,Maff,Phlda1,Btg2,P2ry14,Egr1,Atf3,Nfkbiz,Cd80,Sdc4,Slc25a25,Jun,Fos,Ccl12,Nr4a1,Dusp4,Dusp2,Il6,Spry2,Edn1,Ier3,Trib1,Itpkc,Sema4c,Nfil3,H3f3b,Rgs1,Gem,Il10,Birc3,Rhou,Ccrl2,Zfp36 |
| 1.907e-29 | -66.13 | GSE45365_WT_VS_IFNAR_KO_CD8A_DC_DN | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_CD8A_DC_DN | 179 | 68 | 15632 | 1249 |
Arid5a,Stat5a,Ehd1,Phf11b,Tlk2,Dhx58,Casp3,Stat3,Ifi44,Kmo,Ifih1,Sphk1,Mxd1,Tnfaip3,Gbp2,Plagl2,Bmp2,Ppp1r15a,Irf7,Pde4b,Csf3,Wars,Rapgef2,Parp12,Cxcl2,Ube2l6,Pdgfb,Nmi,Slc2a6,Slc43a3,Herc6,Smox,Ptger4,Il15ra,Glrx,Cxcl1,Hivep2,Nfkbia,Spsb1,Slc7a11,Rin2,Peli1,Fpr2,Il4ra,Tap1,Zc3hav1,Phf11c,Sdc4,Pfkfb3,Cd80,Phf11a,Cdc42ep2,Rel,Tnfrsf1b,Rnf19a,Trim21,Psme2,Parp11,Phf11d,Itga9,Tlr2,Ebi3,Ptgir,Ell2,Itpkc,H3f3b,Tnip1,Tnfaip2 |
| 1.907e-29 | -66.13 | GSE17721_PAM3CSK4_VS_CPG_4H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_4H_BMDC_DN | 179 | 68 | 15632 | 1249 |
Map2k1,Serpine1,Cd274,Klf2,Tap2,Cnp,Slc12a9,Ccnj,Dgka,Wars,Trim26,Pim1,Tmem229b,Ptgs2,Atp10a,St3gal1,Epsti1,Serpinb2,Gca,Clic4,Gtpbp2,Cd40,P2ry12,Itpr1,Psmb9,Atp13a1,Dbnl,Tnfsf8,Gbp3,Isg15,Zfp281,Ch25h,Mxd1,Irf2,Aim2,Rab3ip,Myd88,Irf8,Mov10,Tor3a,Met,Htra1,Timeless,Psme2,Akt3,Cysltr2,Ms4a6d,Irf1,Mmp9,Lrrc8c,Vrk2,Pmepa1,Kdr,Arf4,Dnaja1,Tra2a,Cept1,4932438A13Rik,Nat2,Ccl2,Edn1,Arl4a,Kat2b,Rars,Pgs1,Enpp4,Zbp1,Hinfp |
| 2.197e-29 | -65.99 | WALLACE_PROSTATE_CANCER_RACE_UP | MSigDB lists | WALLACE_PROSTATE_CANCER_RACE_UP | 249 | 81 | 15632 | 1249 |
Ctsc,Fcgr2b,Nat2,Dusp2,Stap1,Optn,Gadd45g,Ifit1bl1,Plac8,Bcl2a1b,Gpr18,Ets2,Il15,Gng11,Ifi207,Tap1,Dnase1l3,Ddx60,P2ry14,Ifi214,Irs2,Isg20,Ifi211,Xaf1,Cd69,Rasgrp1,Ifi203,Psmb8,Itgal,Irf8,Ifit3,Mndal,Hcls1,Ccl4,Rgs1,Nfil3,Mmp9,Stat1,Pim2,Irf1,Ifi204,Ifit3b,Ifi44,Sele,Fgl2,Ccnd1,Rsad2,Bcl2a1d,Cebpd,Dock10,Ifi213,Psmb9,Ifi209,Ifi205,Cd83,Sla,Itga4,Isg15,Socs1,Sell,Ube2l6,Ifi208,H2-Aa,Slc7a5,Parp12,Oas2,Ifit1bl2,Plek,Ccl5,Cd86,Tap2,Samsn1,Lcp2,Bcl2a1a,Tfec,Glrx,Herc6,H2-Ab1,Serpinb9,Il2rg,Nr4a3 |
| 2.881e-29 | -65.72 | GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | 175 | 67 | 15632 | 1249 |
Cd38,Pml,Isg15,Ifih1,Ddx58,Hif1a,Usp18,Stat2,Dennd1b,Fchsd2,Ifi44,Rsad2,Psma6,Dhx58,Nfkbie,Sp140,Casp1,N4bp1,Phf11b,Ifit2,Oas3,Homer1,Snapc1,Trafd1,Ppp2r2a,Sp110,Slc31a1,Oas1g,Herc6,Tlr3,Larp1,Serpinb9,Nmi,Ube2l6,Oas2,Parp12,Ifit1bl2,Irf7,Adar,Phf11a,Phf11c,Tap1,Ddx60,Rtp4,Etv3,Stap1,Eif2ak2,Ifit1bl1,Zcchc2,Oasl1,Ifi35,Ifit3b,Phf11d,Plscr1,Trim21,Isg20,Tdrd7,Cd69,Dcp1a,Xaf1,Slc39a14,Oas1a,Lnpep,Lap3,Casp4,Irf8,Ifit3 |
| 3.337e-29 | -65.57 | positive regulation of innate immune response | biological process | GO:0045089 | 189 | 65 | 20694 | 1406 |
Tlr6,Nlrc4,Ifi205,Zbp1,Tlr3,Ddx58,Ifi209,Clec4e,Tlr2,Prkce,Irf7,Cav1,Tnip1,Cd300lf,Irak2,Ifi211,Mndal,Dhx58,Zc3hav1,Lgals9,Mapkapk2,Raet1e,Klrk1,Ikbke,Wdfy1,Tifa,Ripk2,Ifi208,Parp9,Irgm2,Peli1,Plscr1,Treml4,Cd86,Trim12c,Il18rap,Ifi203,Fpr2,Pvr,Ankrd17,Ifih1,Tnip3,Nod2,Cd14,Irak3,Ifi214,Il12b,Cgas,Nr1h3,Nectin2,Tlr1,Cd74,Ddx60,Nlrc5,Aim2,Tnf,Ifi204,Rsad2,Stat5a,Irgm1,Myd88,Nfkbia,Tlr9,Rasgrp1,H60b |
| 3.915e-29 | -65.41 | positive regulation of molecular function | biological process | GO:0044093 | 1641 | 234 | 20694 | 1406 |
Psme1,Pdgfc,Mlkl,Hmga2,Il1b,Pmaip1,Trib3,Asap3,Ikbkg,Tlr3,Psmd10,Prkce,Cdk5r1,Ccnd1,Plek,Prnp,Cacnb3,Plk2,Thbs1,Bmp2,Psme2,Ccnd2,Il6,Tnfrsf8,Cflar,Tor1aip2,Ppp1r15a,Mmp25,Gdf15,Mefv,Gadd45b,Txn1,Il1rn,Agrn,Il12b,Eno1,Dnajb4,Rgcc,Egr1,Tagap,Met,Tnfsf10,Myd88,Ift57,Fcgr2b,Sdc4,Gch1,Casp8,Cdkn1a,Mdfic,Cx3cl1,Arhgap26,Cacna1d,Kitl,Nlrp3,Ranbp2,Ahsa1,Rgs14,Zc3hav1,Nlrc4,Tlr6,Jak2,Stat1,Crkl,Sphk1,Rin2,Rap1gap2,Hmgn3,Traf5,Ripk3,Cd200,Ddx58,Rictor,Trib1,Cycs,Src,Stat3,Bcl2l11,Cox17,Dock10,Map2k1,Hcls1,Fpr2,Ptafr,Flt1,Pdgfb,Dnaja2,Psma6,Tnfsf15,Lpar1,Fzd5,Dcp1a,Pdgfrb,Htr2a,Pde5a,Myc,Ccl8,Nr1h3,Ccl9,Ptk2,Sipa1l1,Ifrd1,Hspa2,Antxr1,Tor1aip1,Dock4,Dennd1b,Csf1,Dnajb2,Spry2,Ccl2,Adrb2,Arrdc4,Tlr9,Apaf1,Fcgr1,Slc9a1,Glrx,Phactr4,Dcun1d3,Ccl7,Eif2ak2,Ppm1k,Map3k8,Sirt1,Mmp9,Plcl2,Ccl22,Arf4,Pik3r6,Trim13,Lgals9,F11r,Htr2b,Lmo4,Tbc1d13,Cav1,Lyn,Plscr1,Tank,Rapgef2,Hsph1,Rgs3,Adora2b,Acsl1,Higd1a,Traf1,Abr,Mmd,Malt1,Tbc1d1,Arid5b,Rnf31,Tlr1,Cd74,Cd40,Map3k6,Fgr,Mtdh,Icam1,Ccl5,Trim14,Nod1,Kat2b,Angpt1,Pik3r5,Ccl12,Rasgrp1,Pml,Bambi,Ccl4,Syk,Tpx2,Ric1,Ccl3,Daxx,Tnf,Mapkbp1,Fzd1,Jun,Fam162a,Il18,Irak2,Sele,Rgs1,Crbn,Uaca,Tlr2,Pim1,Cdc42ep2,Csf3,Trim26,Map4k4,Casp4,Il18rap,Casp1,Hap1,Traf2,Nek6,Nos2,Tab2,Irgm2,Ripk2,Parp9,Mul1,Irf4,Gadd45g,Dtx3l,Irak3,Gclm,Sav1,Rhoc,Elmod2,Stap1,Edn1,Trim21,Dnaja1,Fas,Lrp8,Pkp4,Mtcp1,Nod2,Adap2,Map2k4,Plaur,Ppp1r15b,Il10,Cx3cr1,S100a8,Cenpe,Atp2b4,Abcb1a,Plpp3,Aim2 |
| 4.025e-29 | -65.38 | GSE24726_WT_VS_E2_2_KO_PDC_DAY4_POST_DELETION_UP | MSigDB lists | GSE24726_WT_VS_E2_2_KO_PDC_DAY4_POST_DELETION_UP | 186 | 69 | 15632 | 1249 |
Odc1,Mafg,Sema4a,Ppa1,Il13ra1,Agpat4,Lrrc8c,Gfpt1,Plekhg1,Birc3,Psmb8,Leng9,Egln3,Pstpip2,Plscr1,Nfkbib,Ciapin1,Slc16a1,Cdc42ep2,Tspo,Spic,Mrpl52,Jun,Agrn,Ppp1r14b,Mllt6,Cept1,Il18bp,Cox17,Ift57,Gclm,Spry2,Pla2g4a,Grina,Ttc39b,Parp3,Lacc1,Tfec,Snapc1,Cmklr1,Irak2,Cldnd1,Gcnt2,Samsn1,Rgl1,Slc31a2,Hsd17b12,Rapgef2,Mmp13,Rab10,Nrp2,H2-Aa,Slc2a6,Cd74,Kmo,Mthfr,Traf5,Ube2f,Ttc39c,Psmb9,Traf2,Homer1,Ddhd1,Ifnar1,C1ra,Stk40,Cebpd,Nr3c1,Cish |
| 4.200e-29 | -65.34 | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_UP | 181 | 68 | 15632 | 1249 |
Epsti1,Gtpbp2,Plcl2,Mitd1,Tnfsf10,Cox18,Crkl,Mmp13,Tbc1d13,Caml,Sap30,Stxbp3,Cd86,Lad1,Serpine1,Golga3,Ccnj,Plek,Prpf38a,Sav1,Ifih1,Nfkbil1,Hhex,Rhoh,Acvr1,Ythdf1,Ly75,Batf2,Rab9,Socs7,Fscn1,Notch2,Kdr,Rgs1,Odc1,Azi2,Tnfsf4,Ebi3,Casp7,Kpna3,Ccrl2,Isg20,Plscr1,Htra1,Timeless,Casp4,Ogfr,Tor3a,Atm,Slc28a2,Dusp14,Hinfp,Arl4a,Slc30a1,Rtp4,Atf3,Rars,Rin2,Cept1,Cox17,Ankrd24,Dtnb,Ccl2,Nat2,Aftph,Dusp2,Il4i1,B4galt4 |
| 6.378e-29 | -64.92 | Immune System | REACTOME pathways | R-MMU-168256 | 1678 | 272 | 8608 | 757 |
Clec5a,Sqstm1,Mapkapk2,Il4ra,Crkl,Il12b,Rnf114,Mmp25,Hvcn1,Rnf19b,Nck1,Ikbkg,Acpp,Cd14,Tyk2,Casp3,Cd180,H2-M2,H2-Aa,Malt1,Phlpp1,Dync1i2,Ptprj,Tlr1,H2-Ab1,Nfkbib,Tnfaip3,Stat2,Syk,Cd200,Isg15,Cd200r4,C1ra,Rhof,Dbnl,Map2k4,Il12rb1,Nfkb1,Spred1,Irf2,Enpp4,Rap2c,Uba7,Src,Cxcl3,Rasgrp1,Slpi,Serpinb6b,Spsb1,Prkar2b,Dusp5,Ifitm1,C3,Kif3c,Mdm2,Birc3,Ube2l6,Ptpn2,Itgal,Osm,Psme2,Csf3,Tax1bp1,Psma6,Trib3,Lcn2,Traf2,Ddx58,Il1a,Irf1,Ifna1,Il2rg,Mvp,Trim21,Cnn2,Pdgfb,Cd34,Pfkl,Txn1,Kitl,Cxcl2,Gsdmd,Nfkb2,Tnf,Pdzd11,Pik3cd,Stat5a,Ifna6,Lcp2,Fgr,Jun,Tnfrsf14,Herc6,Cd300lf,H2-T24,Psmb10,Tnfsf8,Hk3,Icosl,Hp,Rap1gap2,Clec4n,Socs1,Peli1,Lif,Nr4a1,Trim36,Fgl2,Tlr9,Gca,Nod2,Ifna5,Lyn,Tap2,Lgals9,Nod1,Fpr2,H2-Q7,Psmb6,Aim2,Dusp4,Pgm1,Psme1,H2-T10,Trem1,Ptk2,Ier3,Casp8,Tlr2,H2-Q6,Cd80,Tnfsf4,Ube2e1,Plac8,Actb,Tnfsf14,Myo10,Cd274,Jak2,Mmp9,Olr1,Cd86,Socs3,Ubr4,Tarm1,Ppp2r5a,Tab2,Usp18,Treml4,Psmb9,Cyfip1,Itpr1,Mefv,Apaf1,Ikbke,Cenpe,Slamf7,Irf7,Csf3r,Nlrp3,Sec24b,Myd88,Hspa1b,Relb,Il10,H2-Q4,Vcam1,Sec24a,Rnf19a,H2-T22,Tnfrsf8,Dtx3l,Il1b,Fpr1,Il18,Cxcl1,Plaur,Icam1,Rab10,Il6,Phlpp2,Angpt1,Atp11b,Rapgef2,Ebi3,Dusp6,Lnpep,Serpina3f,Trim56,Gpr84,Stat3,Met,Znrf1,Ripk2,Psmb8,Atp11a,Tap1,Pdgfrb,Ifna2,Ksr1,Nfkbia,Tlr6,Dync1h1,Plau,Itgav,Ifnar1,Il1rn,S100a8,Irs2,Rictor,Fos,Evl,Ampd3,Tnfsf9,Tlr3,Pnp2,Il18rap,Il15ra,Rel,Il13ra1,Fcgr4,Cd55,Cish,Vasp,Nectin2,Clcf1,Il27,Klrk1,Psmd10,H2-Eb1,Prkce,Il18bp,Zbp1,Fcgr2b,Atp6v1d,Clec4d,Ppp2r1b,Eif4g2,Il15,Birc2,Armc8,Casp1,Fbxo4,Psme2b,Nfkbie,Irak2,Sell,Cd300e,Fcgr1,Ifna4,Stat1,Cd74,Pde1b,Irak3,Flnb,Ifnb1,Cd40,Ptafr,Ctsc,Itga4,Rnaset2b,Nos2,Tnfsf15,Treml2,Map3k8,Rnaset2a,Map2k1,Tnfrsf1b,Bst1,Cdkn1a,Tapbp,Clec2d |
| 6.434e-29 | -64.91 | GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | 167 | 65 | 15632 | 1249 |
Ube2l6,Pde7b,Cxcl2,Mmp13,Ccl5,Gdf15,Ifit1bl2,Serpine1,Irf7,Ascc3,Plk2,Asns,Clic4,Il1rn,Cmpk2,St3gal1,Ptprj,Il2rg,Clec4d,Ifi44,Egr2,Ly75,Rsad2,Mlkl,Abcc5,Ifit2,Cd83,Pml,Cd74,Usp18,Cd180,Ddx58,Alas1,Srxn1,Xaf1,Met,Ikbkg,Mov10,Zc3h12c,Ifit3,Rgs1,Tnfaip2,Zcchc2,Stat1,C3,Tnfsf4,Cpeb4,Mthfd2,Ifit3b,Tnip3,Odc1,Stap1,Nqo1,Samd9l,Sqstm1,Ccl12,Ifit1bl1,Spic,Fos,Znfx1,Clec4e,Slamf7,Samhd1,Atf3,Ddx60 |
| 9.705e-29 | -64.50 | GSE2706_UNSTIM_VS_8H_LPS_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_DC_DN | 168 | 65 | 15632 | 1249 |
Pim3,Il15,Pnpt1,Rbm43,Rtp4,Gbe1,Ddx60,Optn,Vcan,Ifnb1,Bnip3,Parp14,Il6,Peli1,Gramd1a,Eif2ak2,Znrf1,Tnip1,Tnfaip2,Rgs1,Adam19,Trib1,Rcn1,Dram1,Socs3,Ptgir,Cd200,Stat4,Psme2,Nfkb1,Dcun1d3,Tnfaip3,Myo10,Batf,Icam1,Dtx3l,Aim2,Mxd1,Pml,Csrnp1,Mecp2,Stat3,Itgb8,Dusp1,Usp53,Trafd1,Irak2,Plat,Kcna3,Grina,Dusp5,Ripk2,Pcgf5,Stx11,AA467197,Ext1,Nmi,Tap2,Irf7,Sipa1l1,4930523C07Rik,Nampt,Txn1,Map4k4,Gch1 |
| 1.395e-28 | -64.14 | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP | 505 | 120 | 15632 | 1249 |
Ltbp2,Heatr6,Gbp7,Ifit3,Plscr1,Bcl9,Ifi203,Stat1,Ifi35,Casp7,Etnk1,Tlr2,Irf1,Clcf1,Actb,Ccl12,Ifit1bl1,Myc,Irgm2,Il18bp,Egr1,Dtwd1,Plagl1,Phip,Zbp1,Rbm43,Adar,Pnpt1,Rnd3,Samhd1,Angpt1,Ifit1bl2,Plk2,Ifi208,Oas2,Uba7,Fndc3a,Lox,Cxcl10,Gca,Slfn9,Slfn3,Trafd1,Cmpk2,Plekhf2,Ifi213,Ifi205,Pnp2,Ly75,Pde1b,Tbc1d1,Cebpd,C1ra,Lztfl1,Irf2,Socs1,Isg15,Stat2,Daxx,Tor3a,Lmo4,Mndal,Alas1,Tifa,Ifi211,Csf1,Trim21,Kctd12,Mmd,C3,Oasl1,Max,Ifit3b,Ifi204,Pmepa1,Ppfibp2,Sod2,Gadd45b,Eif2ak2,Slfn8,Tor1aip2,Parp9,Rin2,Usp25,Ddx60,Nck1,Fas,Cdk5r1,Rtp4,Ifi214,Ahr,Ifi207,Dusp6,Ccl5,Pdgfrb,Irf7,Tor1aip1,Slfn4,Tap2,Parp12,Parp3,Tlr3,Osgin2,Cxcl1,Sp110,Rcl1,Abcc5,Ifit2,Oas3,Ifi209,Bcl6,Slc39a4,Cp,Ifi44,Rsad2,Prdm1,Ifih1,Psmb10,Usp18,Myd88 |
| 1.824e-28 | -63.87 | GSE17721_CTRL_VS_CPG_6H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_6H_BMDC_DN | 190 | 69 | 15632 | 1249 |
Tmem229b,Slamf8,Chic2,Slc31a1,Il15ra,Pkp4,Ptges,Plcl2,Gtpbp2,Slfn3,Ralgds,Inpp1,Slfn4,Cacybp,Asns,Ppp1r15a,Igsf8,Vps54,Ccnj,G3bp2,Maff,Icosl,Tmeff1,Trim26,Rilpl1,Stxbp3,Stat2,F11r,Itga4,Rab3ip,Plagl2,Prpf38a,Gbp2,Batf,Bfar,Homer1,N4bp1,Acvr1,Mecp2,Dhx58,Endod1,Cd200,Dusp16,Fscn1,Kdr,Lmo4,Pdk3,Hat1,Gmppb,Atf3,Rars,Mapkapk2,Stxbp1,Tap1,Olr1,Slc28a2,Rnd3,Rbm43,Znfx1,Tiparp,Ets2,Morc3,Ccl12,Cnot4,Parp14,Irgm2,Mmp14,Ppp2r5a,Stard5 |
| 2.068e-28 | -63.75 | GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDC_UP | 180 | 67 | 15632 | 1249 |
Mdfic,Itga4,Mxd1,Calcrl,Fam133b,Icam1,Traf1,Arg2,Rffl,Aebp2,Dusp1,Slc25a37,Spryd7,Gypc,Klhl25,Plcl2,Plat,Tnfsf10,Chic2,Kcna3,Serpinb9,Cdc42ep4,Lox,Gpr85,Sh3bp4,Car13,Cd86,Med21,Rnd3,Olr1,Nfkbiz,Prnp,Irs2,Rtp4,Ccl2,Pdpn,Ifrd1,Kremen1,Vcan,Ift57,Gadd45b,Klf3,Slc7a11,Fos,Ets2,Jun,Tax1bp1,Ap3m2,Pmepa1,Cdkn1a,Denr,Cd200,Rcn1,Acsl1,Plscr1,Htra1,Nfkbib,Mmd,Jag1,Stat4,Etv6,Il10,Rel,Irf8,Gbp7,P2ry2,Ptch1 |
| 2.122e-28 | -63.72 | GSE7509_UNSTIM_VS_FCGRIIB_STIM_DC_DN | MSigDB lists | GSE7509_UNSTIM_VS_FCGRIIB_STIM_DC_DN | 160 | 63 | 15632 | 1249 |
Ccl5,Psd4,Nampt,Serpinb9,Parp3,Rnf19b,Trafd1,Sp110,Epsti1,Il15ra,Clic4,Irak2,Tnfsf10,Oas3,Psmb9,Ppp6r1,Casp1,Cst7,Ifit2,Mlkl,Fgl2,Batf2,Psmb10,Isg15,Socs1,Usp18,Icam1,Ch25h,Malt1,Daxx,Notch1,Gnb4,Nod1,Cenpj,Lap3,Casp4,Lmo4,Itgal,Psmb8,Il18rap,Xaf1,Cd69,Ccrl2,Psme2,Ampd3,Cysltr2,Trim21,Asb13,Parp11,Irf1,Il13ra1,Casp7,Rgs1,Rnf114,Gsdmd,Nfkbia,Ikzf1,Pla2g4a,Stxbp1,Tnfrsf14,Slamf7,Tspo,Ciita |
| 2.854e-28 | -63.42 | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_UP | 186 | 68 | 15632 | 1249 |
Mov10,Ogfr,Tor3a,Jdp2,Rnf19a,Ociad1,Csf1,Timeless,Rcsd1,Ebi3,Tmem219,Nlgn2,Polr2g,Clcf1,Kdr,Rgs1,Cenpe,Gadd45b,Crbn,Itgav,4932438A13Rik,Pdpn,Ccl2,Dusp2,Slc30a1,Rtp4,Stxbp1,Usp25,Atp11b,Tnks1bp1,Sdc4,Hinfp,Adar,Serpine1,Atp6v1d,Irf7,Ccnj,Snx10,Jarid2,Caml,Cox18,Tmem229b,Larp1,Fndc3a,Sec24b,Ppp2r2a,Pcdh7,Plcl2,Gtpbp2,Gcnt2,Plat,Psmb9,Rgs14,Tcf4,Gpsm2,Parp8,Apobec3,Hdac1,Atp13a1,Sat1,Nr3c1,Usp18,Zfp281,Slco3a1,Irf2,Rhoh,Mdfic,Ube2f |
| 2.854e-28 | -63.42 | GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_DN | MSigDB lists | GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_DN | 186 | 68 | 15632 | 1249 |
Map3k8,Cxcl10,Rcan1,Ptgs2,Pim1,Hmox1,Il1b,Plaur,Plat,Serpinb2,Il1rn,Cxcl1,Serpine1,Ppp1r15a,Cd86,Gja1,Junb,Cxcl2,Phlda1,Btg2,Upp1,Il1a,Icam1,Mcoln2,Ier2,Slc30a4,Ch25h,Relb,Cd14,Cd83,Tank,Txnrd1,Ehd1,Dusp1,Stk40,Mdm2,Errfi1,Egr2,Slc39a4,Map2k4,Ier3,Irf1,Lpar1,Socs3,Cdkn1a,Tax1bp1,Il10,Birc3,Kctd12,Procr,Il4ra,Ccnd2,Pgm1,Egr1,Nfkbiz,Dnaja1,Ets2,Fos,Nfkbia,Nr4a1,Gadd45b,Gadd45g,Ifrd1,Peli1,Myc,Ccl2,Dusp2,Mmp14 |
| 2.854e-28 | -63.42 | GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_DN | MSigDB lists | GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_DN | 186 | 68 | 15632 | 1249 |
Rgs1,Cflar,Vrk2,Ppfibp2,C3,Ell2,Dram1,Acsl1,Phf11d,Tnip3,Ampd3,Psme2,Pstpip2,Isg20,Egln3,Jag1,Dcun1d3,P4ha1,Nfkb1,Lap3,Slamf7,Phf11a,Clec4e,Slc25a25,Phf11c,Ahr,Lrp8,Etv3,Slc44a1,Dusp4,Ifrd1,Nfkbia,Gramd1a,Trip10,Tspan3,Irak2,Clic4,Ikbke,Cldnd1,Acsl5,Plaur,Dusp5,Smox,Rnf19b,Clec4d,Ak4,Tmeff1,Inhba,Rapgef2,Gch1,Snx10,Irf7,Osm,Serpine1,Batf,Hck,Csrnp1,Psme1,Irf2,Traf1,Sphk1,Ifih1,Rffl,Gpr84,Casp1,N4bp1,Phf11b,Tank |
| 3.036e-28 | -63.36 | GSE22282_HYPOXIA_VS_NORMOXIA_MYELOID_DC_UP | MSigDB lists | GSE22282_HYPOXIA_VS_NORMOXIA_MYELOID_DC_UP | 181 | 67 | 15632 | 1249 |
Tnip1,Agpat4,Mtmr14,Stat1,Ppa1,C3,Tlr2,Rab20,Psme2,Smpdl3b,Pla2g7,Ccrl2,Rnf19a,Hivep3,Cav1,Lmo4,Clec4e,Fpr2,Dcp2,Sdc1,Tor1aip2,Mmp14,Igsf6,Mllt6,Ift57,Nfkbia,Sod2,Rapgef5,Flrt3,Psmd10,Mrpl52,Il1rn,Acsl5,Plat,Fmnl2,Hp,Rnf19b,Ptger4,Slc31a1,Clec5a,Slc2a6,Stx11,Cxcl2,Pde4b,Junb,Ccl5,Myd88,Ube2f,Cd38,Tnfaip3,Myo10,Mvp,Ch25h,Marcksl1,Nupr1,Tulp3,Icam1,Gpr84,Sele,Nfkbie,Prdx5,Cers6,Ehd1,Tnf,N4bp1,Cd302,Hspa1a |
| 3.258e-28 | -63.29 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_UP | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_UP | 171 | 65 | 15632 | 1249 |
Otud1,Slc25a37,Tnf,Ehd1,Bcl2a1d,Stat3,Cish,Itgb8,Il1a,Upp1,Socs1,Mcoln2,Zfp319,Plagl2,Myo10,Irak3,Batf,Sav1,Cd274,Csf3,Tmeff1,Tnfsf15,Pim1,Osgin2,Ptgs2,Il12b,Zc3h12a,Traf3ip2,Sec24b,Bcl2a1a,Acsl5,Plat,Mrpl52,Trip10,Ets2,Gadd45b,Trim36,Nfkbia,Flt1,Plac8,Gramd1a,Bcl2a1b,Scarf1,Kcnj2,Il6,Fpr2,Papss2,Enpp4,Pfkfb3,Il10,P2ry2,Dcun1d3,Tnfrsf1b,Stat4,Usp12,Met,Akt3,Pdss1,Tnip3,Acvr1b,Ier3,Ell2,Socs3,Agpat4,Adam19 |
| 3.435e-28 | -63.24 | cytosol | cellular component | GO:0005829 | 3206 | 372 | 20747 | 1409 |
Cdkn2d,Hcls1,Hspa1a,Oasl1,Cenpe,Palld,Rnf114,Ass1,Dennd1b,Dennd2a,Hif1a,Tent2,Fndc3a,Gsta3,Tbc1d13,Nfkbil1,Ascc3,Agrn,Relb,Ccnd2,Ifi205,Pdzd11,Mxd1,Ifi211,Nqo1,Pikfyve,Htr2a,Sqstm1,Zfp36,Ifi208,Serpinb9,Ahr,Parp9,Ddit4,Gbp2,Lcn2,Ifi203,Setdb2,Plscr1,Pttg1,Uchl1,Rpgrip1l,Gca,Srxn1,Glrx,Parp10,Stxbp1,Carhsp1,Golga3,Sphk1,Ifit1bl1,Dusp6,Rac3,Malt1,Psmd10,Ptk2,Pnp2,Nfkb2,Herc3,Fgr,Usp18,Gbp2b,Nfkb1,Nupr1,Arel1,Igtp,Tnip1,Nos2,Dnajb2,Usp25,Ahrr,Birc3,Slc2a1,Ets2,Mdm2,Usp12,Rilpl1,Zbp1,Riox2,Lipe,Sav1,Asns,Traf5,Fut8,Inpp5b,Ppp2r2a,Nlrc5,Stat2,Pim1,Eif4g2,Stat5a,Fscn1,Shfl,Dgka,Rel,Arid4a,Nfkbib,Me1,Nr4a1,Rbms1,Stk40,Ifit1,Il1a,Ctu1,Tab2,Irs2,Fam129a,Hsph1,Casp4,Marcksl1,Gch1,Daam1,Ntng2,Hspa2,Gbp3,Prkce,Jak2,Egln3,Txnrd1,Fam72a,Eno2,Dtx3l,Rnf31,Casp7,Agtrap,Pfkl,Mvp,Kdm5b,Pdgfc,Esd,Dse,Tasor2,Pml,Ripk3,Lif,Jun,Oasl2,Lgals9,Psmb9,Zeb1,Cyth3,Etnk1,P4ha2,Ampd3,Sbds,Dnajb4,Hap1,Irf2,Hspa1b,Rab3ip,Flnb,Klf6,Ddx60,Osbpl3,Aim2,Fabp7,Nmi,Gsdmd,Irf7,Fas,Rai14,Rap1gap2,Tha1,Ubr4,Parp14,Oas1b,Rnf19b,Bbx,Ahsa1,Slc37a3,Map2k1,Myo10,Casp1,Fam162a,Alas1,Socs7,Cdkn1a,Zc3hav1,Nlrc4,Apaf1,Tpi1,Fabp3,Spata13,Pik3r5,Optn,Ifit1bl2,Mcmbp,Rbms2,Psat1,Ezr,Vezt,Prnp,Lcp2,Eif2ak2,Nod2,Nfkbia,Dock4,Pde5a,Acvr1b,Tut7,Kat2b,Cav1,Stat3,Etv6,Msr1,Tgs1,Dck,Sass6,Nat2,Rims3,Hk1,Dusp8,Kdm4a,Ldha,Dnaja2,Rhoc,Cgas,Gja1,Cnn3,Ddx58,Lap3,Pfkfb3,Pnpt1,Oas3,Spire1,Actb,S100a8,Casp8,Cflar,Cdc42ep2,Car13,Carmil1,Whamm,Clcn5,Rabgef1,Irgm2,Bcl2l11,Dusp16,Zhx2,Arl4a,Oas1a,Naa25,Cacybp,Oas1g,Ifi213,Dock10,Vasp,Uaca,Sat1,Tank,Rbpms,Gclc,Pstpip2,Fmnl2,Prkx,Wdfy1,Rars,Ripk2,Rasgrp1,Crlf3,Ralgds,Nfkbie,Nek6,Ptgir,Mmp14,Herc6,Daxx,Sec24b,Spred1,Ggct,Hk2,Stat4,Pla2g4a,Rapgef2,Lztfl1,Stx6,Hmox1,Pgk1,Prdx5,Mt1,Gpc1,Stat1,Plekha5,Prkar2b,Hdc,Rgs1,Dyrk2,Jmjd6,Keap1,G3bp2,Ifit3,Src,Lrch3,Gsr,Pde4b,Arf4,Xrn1,Abr,Rab11fip1,Eno1,Prdx1,Kmt5a,Gk,Znrf1,Samsn1,Ikbkg,Spsb1,Ifi204,Slc7a5,Cnp,Chmp4b,Spry2,Casp3,Oas2,Ptpn2,Selenow,Wars,Grk3,Dnaja1,Nlrp3,Odc1,Sirt1,Klf8,Ppp6r1,Map3k8,Ifi214,Clec5a,Mdn1,Il15,Flrt3,Pim3,Clic4,Psmb6,Mecp2,Ifi209,Rgs3,Hk3,Cycs,Crkl,Zyx,Stxbp3,Txn1,Ifi207,Rnf14,Mndal,Igf2bp2,Mov10,Sema4a,Myd88,Pdpn,Hmgcs1,Eef1e1,Mthfr,Itgav,Errfi1,Smg7,Stau1,Map2k4,Gpsm2,Casz1,Ifit3b,Asap3,Ifit2,Cutc,Nr3c1,Aftph,Ric1,Rap2c,Ppp2r5a,Traf2,Hdac1,Homer1 |
| 3.478e-28 | -63.23 | positive regulation of signal transduction | biological process | GO:0009967 | 1511 | 219 | 20694 | 1406 |
Scimp,Zc3hav1,Akt3,Clec4n,Ripk3,Traf5,Cysltr2,Inhba,Irf7,Tnfaip3,Rictor,Jak2,Tlr6,Zbp1,Sphk1,Crkl,Hcls1,Map2k1,Fpr2,Peli1,Bcl2l11,Stat3,Src,Treml4,Nr3c1,Ikbke,Lpar1,Tnfsf15,Usp12,Flt1,Lif,Pdgfb,Prag1,Ccl9,Nr1h3,Ptk2,Pdgfrb,Plagl2,Ptpn2,Fzd5,Ccl8,Myc,Pde5a,Htr2a,Nupr1,Csf1,Il15,Spry2,Glrx,Parp14,Ccl2,Slc9a1,Tlr9,Adrb2,Apaf1,Eif2ak2,Ccl7,Map3k8,Glipr2,Rbpms,Cenpj,Ppp2r1b,Eef1e1,Il1b,Ppp2r3a,Pmaip1,Pdgfc,Mlkl,Tnfsf14,Prkce,Crlf3,Nfkb1,Ikbkg,Tlr3,Ctsc,Bmp2,Casp2,Thbs1,Cacnb3,Mid1,Jag1,Cflar,Hif1a,Acvr1b,Il6,Il12b,Traf3ip2,Il1rn,Cgas,Spred3,Gadd45b,Cd14,Bnip3,Gdf15,Notch2,Fcgr2b,Casp8,Acvrl1,Irgm1,Gpr35,Myd88,Met,Tnfsf10,Nck1,Cx3cl1,Mdfic,Kitl,P2ry12,Kdr,Sik3,Nlrc5,Notch1,Gfi1,Zc3h12a,Itgal,Il18,Cd300lf,Irak2,Gpr18,Tlr2,Marco,Ptprj,Hap1,Casp1,Csf3,Gcnt2,Map4k4,Casp4,Wdr59,Tab2,Wdfy1,Tifa,Parp9,Mul1,Ripk2,Irgm2,Traf2,Spred1,Nectin2,Ddx60,Gadd45g,Fas,Nod2,Stap1,Edn1,Sema4c,Acvr1,Intu,Plaur,Map2k4,Cx3cr1,S100a8,Il10,Phlpp1,Hdac1,Adora2a,Ptger4,Dhx58,Pik3r6,Hhex,Lgals9,Trim13,Axl,Sirt1,Mmp9,Ccl22,Clcf1,Cav1,Lyn,Osm,Htr2b,F10,Adora2b,Plscr1,Rapgef2,Ksr1,Atm,Cyfip1,Tlr1,C3,Cd74,Cd180,Malt1,Rnf31,Ccl5,Icam1,Ifnb1,Nod1,Nox1,Phip,Mtdh,Fgr,Nlgn2,Map3k6,Ankrd17,Igf1r,Cd40,Rasgrp1,Ago3,Ccl12,Pim2,Acpp,Atf3,Pml,Ccr1,Angpt1,Pik3r5,Mapkbp1,Tnf,Daxx,Il1a,Ccl3,Fam162a,Jun,Rsad2,Ccl4,Bambi,Syk,Cited2 |
| 4.325e-28 | -63.01 | response to molecule of bacterial origin | biological process | GO:0002237 | 353 | 89 | 20694 | 1406 |
Jun,Tnf,Gch1,Arid5a,Ccl12,Fcgr2b,Myd88,Noct,Ccl5,Cxcl2,Tnip3,Mtdh,Cd180,Il12b,Il1rn,Tlr1,Pde4b,Ednrb,Malt1,Junb,Cd14,Abr,Ptgs2,Il6,Cd80,Slpi,Cd86,Plscr1,Lyn,Nfkb1,Cxcl11,Prkce,Acod1,Itgav,Ifnar1,Lgals9,Irf8,Axl,Mapkapk2,Il1b,Cd274,Acp5,Cxcl1,Eif2ak2,Ptger4,Cx3cr1,Il10,Tnfsf4,Gbp2,Nfkbia,Tlr9,Pf4,Ccl2,Serpine1,Nod2,Tap2,Stap1,Ptgir,Nr1h3,Irak3,Fcgr4,Fzd5,Zfp36,Ripk2,Irgm2,Nos2,Tab2,Cxcl9,Klrk1,Cxcl10,Ptafr,Cmpk2,Casp1,Nfkbil1,Peli1,Trib1,Tnfaip3,Cxcl3,Tlr2,Nfkbib,Stat1,Jak2,Tlr6,Gfi1,Nlrp3,Irak2,Zc3h12a,Tnfrsf1b,Il18 |
| 4.638e-28 | -62.94 | ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP | 402 | 104 | 15632 | 1249 |
Tlr2,Acsl1,Ier3,Tnfaip2,Tnip1,Clcf1,Cflar,Tmem67,Il10,Zc3h12c,Irf8,Ccrl2,Slc39a14,Jag1,Dmxl2,Sgms2,Slc28a2,Fcgr1,Rnd3,Nfkbia,Il6,Edn1,Cxcl10,Il12b,Ptgs2,Zc3h12a,Dusp5,Kdm6b,Cd55,Plaur,Bambi,Serpinb2,Nampt,Maff,Nfkbid,Csf3,Slc2a6,Scn1b,Tnfsf15,Pdgfb,Btg2,Traf1,Slco3a1,Il1a,Icam1,Lif,Relb,Cd83,Dusp1,Dync1h1,Ehd1,Src,Gpr84,Dtx2,Dram1,Cpeb4,Rap2c,Ldlr,Ccl4,Fscn1,Cep350,Rel,Nfkb1,Palld,Gpc1,Clec4e,Cd80,Sdc4,Pim3,Trip10,Sqstm1,Sod2,Spsb1,Trim36,Nr4a1,Gramd1a,Dusp2,Nr4a3,Il18,Rcan1,Ripk2,St3gal1,Snn,Il1b,Irak2,Nfkb2,Cxcl1,Osm,Serpine1,Ppp1r15a,Cxcl2,Car13,Rapgef2,Eya4,Icosl,Plk3,Lrch3,Plagl2,Tnfaip3,Klf6,Tnf,Stat5a,Itgb8,Oaf |
| 4.916e-28 | -62.88 | STK33_NOMO_UP | MSigDB lists | STK33_NOMO_UP | 265 | 82 | 15632 | 1249 |
Mndal,Pid1,Il10,Zfp36,Ifi211,Ifi203,Stx6,Rnf19a,Egr3,Cpeb4,Ier3,Ifi204,Gbp2b,Ccl4,Siglece,Whamm,Lrrc25,Gfpt1,Trem1,Sqstm1,Jun,Dock4,Fos,Peli1,Kcnj2,Samd9l,Rin2,Tlr6,P2ry14,Ifi214,Nkiras1,Cd80,Gng11,Plau,Rnd3,Sdc4,Olr1,Spred1,Ifi207,Gja1,Gdf15,Junb,Nampt,Ppp1r15a,Tnfsf15,Tlr1,Arl5b,Ifi208,Phlda1,Btg2,Cxcl2,AA467197,Maff,Dusp5,Hmox1,Fndc3a,St3gal1,Arid5b,Map3k8,Fcho2,Gcnt2,Kitl,Cxcl1,Il1b,Tfec,Lacc1,Usp53,Dusp1,Ifi213,Klf6,Ifi205,Bcl6,Ifi209,Otud1,Dennd1b,Egr2,Acvr1,Csrnp1,Icam1,Il1a,Upp1,Kmo |
| 5.288e-28 | -62.81 | SANA_TNF_SIGNALING_UP | MSigDB lists | SANA_TNF_SIGNALING_UP | 79 | 44 | 15632 | 1249 |
Rac3,Ripk2,Oas1g,Dram1,Cxcl10,Tlr2,Tnfaip2,Tnip1,Vcam1,Cxcl1,Cmpk2,Ifit1bl2,Birc3,Slc7a2,Serpine1,Csf1,Icosl,Cxcl2,Oas2,Oas1a,Inhba,Ddx60,H2-Q7,Ifih1,Cx3cl1,Icam1,Lipg,Tnfaip3,Samhd1,Casp1,Ccl12,Itgav,Sod2,Nfkbia,H2-Q4,Ifit1bl1,Oas3,Dnaja1,H2-Q6,Slc15a3,Sat1,Parp14,Samd9l,Tapbp |
| 5.355e-28 | -62.79 | GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1556 | 247 | 15632 | 1249 |
Ppp2r5a,Ccl2,Myc,Il6,Peli1,Spry2,Pik3r5,Ccl12,Cenpe,Jun,Gclc,Fbxo4,Prdx1,Ifna1,Mark2,Mapkapk2,Tlr6,Lrp8,Prnp,Phip,Ccl22,Hcls1,Kdr,Prkar2b,Igf1r,Socs3,Acsl1,Acvr1b,Aida,Dbnl,Acvrl1,Acvr1,Lrp4,Ppp6r1,Ifnar1,Dusp1,Psmb9,Swap70,Bmp2,Nod1,Ripk3,Daxx,Pml,Hhex,Psme1,Ube2e1,Sphk1,Fgr,Icam1,Nmi,Tnfsf15,Map4k4,Txn1,Pik3r6,Plcl2,Dusp5,Uchl1,Ptprj,Il12b,Pim1,Stap1,Pde5a,Ifnb1,Dusp4,Phlpp1,Sqstm1,Syk,Spn,Eif2ak2,Dnaja1,Il15,Nck1,Tpx2,Mul1,Psme2,Trim21,Csf1,Mmd,Ikbkg,Dcun1d3,Jdp2,Ppp1r15b,Atm,Rap2c,Ccl4,Jak2,Pmepa1,Vrk2,Cdkn1a,Dusp16,Itga5,Sema4c,Ptk2,Lyn,Trib1,Hspa2,Errfi1,Tnf,Bcl6,Traf2,Tnfaip3,Rgs3,Nupr1,Rnf139,Parp10,Cd74,Fzd1,Rapgef2,Inhba,Ccl5,Gdf15,Myadm,Dusp6,Plek,Ppp1r15a,Lcp2,Flrt2,Irak2,Pilrb1,Ppp2r2a,Crkl,Tlr3,Trib3,Prkce,Edn1,Nod2,Flrt3,Ezr,Flt1,Map3k6,Psmd10,Adar,Htr2a,Angpt1,Tnfrsf14,Atp2b4,Egr1,Atf3,Arrdc4,Ccnd2,Cysltr2,Ksr1,Rasgrp1,Sirt1,Ccne1,Birc3,Rabgef1,Psmb8,Tnip1,Clcf1,Socs7,Gfi1,Nox1,Adrb2,Dusp8,Cish,Casp3,Psma6,Stk40,Ccnd1,N4bp1,Src,Hsph1,Cd40,Birc2,Hspa1a,Rgs14,Mdfic,Lif,Mthfr,Malt1,Isg15,Trim12c,Socs1,Kdm4a,Il1a,Ifna6,Pdgfb,Csf3,Jarid2,Samsn1,Thbs1,Plaur,Vegfc,Zc3h12a,Ptger4,Fpr1,Cxcl10,Dusp2,Gadd45g,Ifna5,Mid1,S1pr2,Ppp1r14b,Gadd45b,Ptpn2,Cd80,Tspo,Pilrb2,Sdc4,Dusp14,Spred1,Bcor,Cdkn2d,Fas,Cx3cl1,Cdk5r1,Kat2b,Ubash3b,Rictor,Tnfrsf1b,Ednrb,Cav1,Pid1,Ppp2r1b,Dnajb2,Mmp9,C3,Tlr9,Lpar1,Stat3,Mecp2,Rbpms,Glipr2,Ifna2,Irak3,Mvp,Ccl3,Pdgfc,Psmb10,Tab2,Ddit4,Ppp2r3a,Ccr1,Map2k1,Osm,Pdgfrb,Fzd5,Kitl,Gcnt2,Htr2b,Il1b,Psmb6,Ripk2,Il18,Map3k8,Adora2b |
| 6.010e-28 | -62.68 | GSE17721_CTRL_VS_POLYIC_8H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_8H_BMDC_DN | 188 | 68 | 15632 | 1249 |
Notch1,Mcmbp,Mdfic,Plagl2,Bfar,Itga4,Pml,Hdac1,Lztfl1,Dhx58,Hspa2,Timp1,Homer1,Itpr1,Stat5a,Ddhd1,Spryd7,Epsti1,Keap1,Il1rn,Gtpbp2,Kitl,Gca,Serpinb9,Slc31a1,G3bp2,Hk2,Tbc1d13,Tyk2,Sap30,Stxbp3,Igsf8,Ccnj,Rgl1,Slc12a9,Slc28a2,Rnd3,Hinfp,Rbm43,Etv3,Palld,Pcx,Irgm2,Ccl2,Hmga1,Plac8,Crbn,Dusp16,Vrk2,Cacna1d,Gfpt1,Jak2,Ms4a6d,Ier3,Ddx4,Ebi3,Endod1,Slamf9,Hat1,Ociad1,Procr,Cav1,Nos2,Lap3,Lmo4,Psmb8,Ccne1,Ppp1r15b |
| 6.483e-28 | -62.60 | GSE41867_MEMORY_VS_EXHAUSTED_CD8_TCELL_DAY30_LCMV_UP | MSigDB lists | GSE41867_MEMORY_VS_EXHAUSTED_CD8_TCELL_DAY30_LCMV_UP | 183 | 67 | 15632 | 1249 |
Ap3m2,Etnk1,Ms4a6d,Aida,Irf1,Rnf145,Cnn3,Trim14,Trim21,Ociad1,Psme2,Tdrd7,Il18rap,Tor3a,Rnf31,Itgal,Irf8,Gbp7,Kif9,Fbxo4,Adar,Chmp4b,Samhd1,Coa5,Parp14,Dusp2,Phlpp1,Mllt6,Nlrc5,Gpr18,Jun,Mitd1,Tfec,5430427O19Rik,Atp10a,Tapbpl,Serpinb9,Il18,Icosl,Trim26,Tlr1,Il12rb1,Plek,Card6,Lgals9,Daam1,Vps54,Cd83,Sgk3,Bmp2,Daxx,Hhex,Csrnp1,Zfp513,Icam1,Stat2,Gbp3,Socs1,Trim12c,Batf2,Slc15a3,Cebpd,Ifit2,Casp1,Mtus1,Oas3,Cd40 |
| 6.608e-28 | -62.58 | GO_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE | 339 | 94 | 15632 | 1249 |
Il6,Ccl2,Prkce,Nod2,Nlrc5,Nfkbia,Ccl12,Psmd10,Tlr6,Mapkapk2,Plscr1,Pla2g7,Ifi203,Rasgrp1,Birc3,Clec4n,Psmb8,Marco,Tnip1,Tnfsf4,Tlr2,Psma6,Src,Ifi213,Psmb9,Birc2,Ifi205,Tank,Nod1,Relb,Hck,Malt1,Psme1,Ddx58,Cd180,Trim12c,Ifi208,Tlr1,Cd86,Ptger4,Ptgs2,Clec4d,Il12b,Pla2g4a,Ifnb1,Syk,Nlrc4,Il15,Clec4e,Ifi207,Zc3hav1,Ddx60,Cx3cl1,Ifi214,Ifi211,Psme2,S100a8,Ikbkg,Nfkb1,Mndal,Casp8,Jak2,Ccl4,Tlr9,C3,Tnip3,Ifi204,Lyn,Dhx58,Tnf,Ankrd17,Ifi209,Myd88,Cd14,Irak3,Tnfaip3,Ccl3,Aim2,Tab2,Ifih1,Psmb10,Gja1,Ccl5,Serpine1,Irf7,Osm,Ikbke,Irak2,Il1b,Tlr3,Psmb6,Ripk2,Adora2b,Il18 |
| 8.298e-28 | -62.36 | GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 359 | 97 | 15632 | 1249 |
Ifi211,Nfkb1,Mndal,Jak2,C3,Tlr9,Ifi204,Syk,Eif2ak2,Spn,Gsdmd,Clec4e,Cd80,Il15,Cd34,Il27,Zc3hav1,Ifi207,Cx3cl1,Ifi214,Il12rb1,Pde4b,Irf7,Serpine1,Cd274,Fzd5,Nfkb2,Htr2b,Il1b,Ripk2,Hmox1,Tlr3,Nr4a3,Il18,Adora2b,Dhx58,Rsad2,Tnf,Ifi209,H2-Q6,Traf2,Ccdc88b,Cd14,Myd88,Aim2,Ifih1,Rnf135,Cd74,Rasgrp1,Ifi203,Clec4n,P2ry2,Il10,Irf8,Nox1,Tnfsf4,Ebi3,Tlr2,Irf1,Peli1,Il6,Irf4,Nod2,Ccl12,H2-Q4,Zbp1,Tnfrsf14,Mapkapk2,Tlr6,Nlrp3,Il4ra,Tlr1,Ifi208,Cd86,Thbs1,Pf4,Ptger4,Il12b,Ptafr,Clec5a,Ptgs2,Ifnar1,Casp1,Ifi213,Src,Ifi205,Hspa1a,Cd40,Tnfrsf8,Cd83,Nod1,Malt1,H2-Q7,Fgr,Hif1a,Il1a,Ddx58 |
| 8.682e-28 | -62.31 | GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_UP | 189 | 68 | 15632 | 1249 |
Serpine1,Cd274,Ppp1r15a,Plk2,Csrp1,Txn1,Slc7a8,Tbc1d13,Il12rb1,Stxbp3,Sap30,Wdfy1,Il2rg,Tmem229b,Cox18,Psmb6,Larp1,Ppp2r2a,Epsti1,Clic4,Gtpbp2,Vcam1,Homer1,Insl6,Klf6,Nfkbie,Ogfrl1,Tnfsf8,Casp3,Fut8,Traf1,Psme1,Aim2,Itga4,Rhoc,Cd164,Rab3ip,Myd88,Lap3,Jdp2,Hk1,Pdk3,Ankib1,Nfkbib,Psme2,Pdss1,Asb13,Cd200,Endod1,Casp7,Ebi3,Cdkn1a,Cflar,Znfx1,Crbn,Nfkbia,Cnn2,Morc3,Kremen1,4932438A13Rik,Il4i1,Bbx,Abcb1a,Tpx2,Usp25,Tlr6,Pgs1,Sdc4 |
| 9.918e-28 | -62.18 | REACTOME_INTERFERON_SIGNALING | MSigDB lists | REACTOME_INTERFERON_SIGNALING | 149 | 60 | 15632 | 1249 |
Ifna2,Gbp2,Isg15,Gbp3,Socs1,Usp18,Stat2,Icam1,Ddx58,Pml,Ube2e1,H2-Q7,Irf2,Gbp9,Gbp4,Oas3,H2-Q6,Ifnar1,Ifit2,Vcam1,Ptafr,Oas1g,Uba7,Tyk2,Oas2,H2-Aa,Ifna6,Ube2l6,Irf7,Ifit1bl2,H2-Eb1,Adar,Fcgr1,Ifna1,Ciita,Egr1,Ifna5,Ifnb1,Irf4,Ptpn2,H2-Q4,Ifit1bl1,Eif2ak2,Jak2,Ifit3b,Irf1,Oasl1,Stat1,Socs3,Ifi35,Kpna3,Xaf1,Oas1a,Flnb,Isg20,Gbp7,Irf8,Ifit3,Eif4g2,Psmb8 |
| 1.390e-27 | -61.84 | regulation of localization | biological process | GO:0032879 | 2818 | 337 | 20694 | 1406 |
Fgr,Nlgn2,Igf1r,Cd40,Pfkl,Msr1,Dync1h1,Slc16a1,Irs2,Ccl5,Rabgef1,Icam1,Hk1,Pde4b,Sec24b,Lipg,Tbc1d1,Oas2,Gsdmd,Actb,Fabp3,C3,Cd74,Tlr1,Pde3b,Syk,Cited2,Stxbp1,Ccl4,Jun,Sod2,Rsad2,Tnf,Plk3,Zswim4,Mapkbp1,Il1a,Ccl3,Rab20,Angpt1,Pml,Ccr1,Rasgrp1,Rras2,Ccl12,Sqstm1,Lmo4,Htr2b,Itpr1,Ptch1,Rims3,Klf7,Lyn,Cav1,Sell,Il4ra,Slc7a11,Osm,Sdc1,Myadm,Ahr,Clcf1,Slc31a2,Ier3,Sirt1,Mmp9,Lgals9,Il15ra,Axl,Acsl5,Gpsm2,Cd274,Ddx4,Atm,Cyfip1,Hilpda,Syne2,Mmd,Abr,Ptgs2,Pik3cd,Cd38,Hsph1,Rapgef2,Spn,Rab9,Stoml1,Adora2b,Rap2c,Dnaja1,Stap1,Edn1,Sema4c,Homer1,Tmsb10,Serpine1,Hvcn1,Carmil1,Pla2g7,Nod2,Flrt2,Fas,Svbp,Itga4,Dtx3l,Zfp36,Mmp14,Rhoc,Clic5,Abcb1a,Plpp3,Atp2b4,Ptger4,Mmp13,Cmklr1,Bst1,Tspo,Rab11fip1,Ehd1,Aim2,Adora2a,Hdac1,Plau,Cx3cr1,Dach1,S100a8,Il10,Rab21,Acvr1,Tnfsf4,Uaca,Crbn,Rnd3,Gpr18,Clec4e,Frmd4a,Tlr2,Hmox1,Cd300lf,Tomm70a,Zc3h12a,Il18,Pid1,Sele,Notch1,Scn1b,Spred1,Traf2,Lrp4,Parp9,Mul1,Ripk2,Gbp4,Rhbdf2,Nos2,Tmod3,Map4k4,Casp4,Mtus1,Clec5a,Gcnt2,Ccne1,Hap1,Casp1,Xcr1,Ptprj,Clic4,Cxcl14,Stxbp3,Srgn,Rab10,Egr1,Rgcc,Sinhcaf,Bcl6,Ednrb,Cd14,Rnd1,Agrn,Il1rn,Txn1,Lztfl1,Ubash3b,Kdr,Sik3,Kitl,Rffl,Cacna1d,P2ry12,Cx3cl1,Mdfic,P2ry2,Nck1,Rtn2,Gpr35,Acvrl1,Serp1,Myd88,Met,Siglece,Spata13,Arid5a,Pla2g4a,Abcc1,Sdc4,Fcgr2b,Slc30a4,Hk2,Gja1,Itgav,Rhof,Ifnar1,Ppp2r5a,Tnfrsf14,Tnfsf14,Nr4a3,Cdk5r1,Prkce,Mdm2,Ttc39b,Pdgfc,Trib3,Fubp1,Pmaip1,Il1b,Ppp2r3a,Hmga2,Pim3,Il6,Acvr1b,Itga5,Hif1a,Dusp1,Il2rg,Cnn2,Jag1,Thbs1,Plk2,Cd34,Cacnb3,Prnp,Fbxo4,Sema4a,Bmp2,Gem,Hspa2,Ifih1,Stx6,Rhoq,Spry2,Col18a1,Dnajb2,Csf1,Dock4,Il15,Hcar2,Myc,Htr2a,Pdgfrb,Ptpn2,Fzd5,Ptk2,Kmo,Prag1,Kdm5b,Prkx,Nr1h3,Mecp2,Vegfc,Cenpj,Glipr2,Stat5a,Cxcl1,Pdpn,Socs1,Slc9a1,Fcgr1,Slamf8,Slc30a1,Tlr9,Dcp2,Nfkbia,Adrb2,Evl,Ccl2,Igsf8,D1Ertd622e,Ezr,Mllt6,Scyl2,Glrx,Sphk1,Crkl,Timp1,Jak2,Tlr6,Spint2,Inhba,Trib1,Tnfaip3,Ddx58,Cd200,Hmgn3,Ripk3,Clec4n,Swap70,Tnfrsf1b,Rnf139,Apba1,Akt3,Nlrp3,Ero1l,Lif,Pdgfb,Cxcl10,Flt1,Arg2,Ptafr,Kcna3,Lrch1,Lpar1,Tnfsf15,Ikbke,Gpc1,Gpr68,Sema3c,Cox17,Nr3c1,Hck,Stat3,Src,Kcnj2,Fpr2,Sec24a,Hcls1,Map2k1,Dock10 |
| 1.472e-27 | -61.78 | GSE17721_0.5H_VS_4H_LPS_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_LPS_BMDC_DN | 180 | 66 | 15632 | 1249 |
Ebi3,Ell2,Dusp16,Frmd6,Atm,Birc3,Tor3a,Nfkb1,Marco,Lmo4,Nos2,Procr,Palld,Stxbp1,Pikfyve,Hinfp,Rbm43,Zbp1,Olr1,Rab32,Crbn,Trmt1l,Ets2,Parp14,Irgm2,Mmp14,Stard5,Slc44a1,Ccl2,Chic2,Il18,Serpinb9,Gca,Keap1,Nampt,Ccnj,Rgl1,Cacybp,Ppp1r15a,Serpine1,Trim26,Rab10,Rilpl1,Stxbp3,Hk2,Ube2e1,Lif,Stat2,Socs1,Rnf34,Batf,Traf5,1600014C10Rik,Stau1,Gbp2,Mcmbp,Stat5a,Tnf,Plekhf2,Gypc,Plekha5,Timp1,Hspa1a,Tcf4,Lztfl1,Stk40 |
| 1.472e-27 | -61.78 | GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_DN | MSigDB lists | GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_DN | 180 | 66 | 15632 | 1249 |
Ifi44,Rsad2,Tlk2,N4bp1,Ifit2,Axl,Birc2,Arid5a,Hck,Malt1,Socs1,Isg15,Stat2,Oas2,Dusp6,Nampt,Slc31a2,Ccr1,Ifit1bl2,Rgl1,Irf7,Lcp2,Myo1b,Cd86,Gca,Cldnd1,Trafd1,Ppp2r2a,Sp110,Oas1g,Rnf19b,Ccl2,Il6,4932438A13Rik,Rin2,Ccl12,Hivep2,Ifit1bl1,Ptpn2,Dnaja1,Adar,Ppfibp1,Zc3hav1,Atf3,Fas,Fpr2,Zfp36,St3gal5,Plscr1,Isg20,Trim14,Trim21,Etv6,Tdrd7,Xaf1,Oas1a,Dach1,Abtb2,Ifit3,Rbms1,H3f3b,Oasl1,Ifi35,Ifit3b,Lyn,Acsl1 |
| 1.472e-27 | -61.78 | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN | 180 | 66 | 15632 | 1249 |
Arf4,Zcchc2,Tnfaip2,Gbp2b,Dusp16,Abcc1,Cpeb4,Ebi3,Pim2,Ier3,Lyn,Mafg,Ifit3b,Procr,Plscr1,Rabgef1,Nfkb1,P4ha1,Tnfsf14,Ifit3,Lcn2,Pilra,Ddx60,P2ry14,Il4i1,Cept1,Scarf1,Ifit1bl1,Eif2ak2,Pik3r5,Sod2,Itgav,Bcl2a1b,Ets2,Bcl2a1a,Nfkb2,Lacc1,Il15ra,Dusp5,Ak4,Nr4a3,Arl5b,Scn1b,Inhba,G3bp2,Spint2,Snx10,Ifit1bl2,Map4k4,Brd2,Tap2,Map2k1,Tab2,Il1a,Ifih1,Sphk1,Dtx3l,Socs1,Fgr,Batf2,Bcl2a1d,Stat5a,Src,Sp140,Mgat1,Oas3 |
| 1.905e-27 | -61.53 | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | 337 | 93 | 15632 | 1249 |
Src,Gpr84,Ddx58,Icam1,Isg15,Socs1,Relb,Ifit1bl2,Nampt,Btg2,Csf3,Maff,Oas2,Cd55,Rnf19b,Oas1g,Zc3h12a,Dusp5,Ptgs2,Cxcl10,Il12b,Serpinb2,Bambi,Plaur,Ifit1bl1,Znfx1,Edn1,Il6,Kremen1,Slc28a2,Zc3h12c,Ifit3,Irf8,Jag1,Oas1a,Ccrl2,Nox1,Acsl1,Ier3,Tlr2,Tmem67,Tnfaip2,Stat5a,Tnf,Ifit2,Oas3,Ifi44,Itgb8,Ch25h,Csrnp1,Usp18,Ifih1,Ncoa7,Ppp1r15a,Serpine1,Irf7,Osm,Rapgef2,Car13,Fzd1,Cxcl2,Il18,Arid5b,Cdc42ep4,Cxcl1,Irak2,Kitl,Nfkb2,Snn,Il1b,Trim36,Spsb1,Rapgef5,Trip10,Ifnb1,Rtp4,Il27,Sdc4,Cd80,Slfn5,Zc3hav1,Dnase1l3,Nfkb1,Rel,Sik3,Ppp4r2,Usp12,Dram1,Oasl1,Itga9,Ifit3b,Fscn1,Ccl4 |
| 2.142e-27 | -61.41 | GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_DN | MSigDB lists | GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_DN | 181 | 66 | 15632 | 1249 |
Tnfaip3,Myo10,Batf,Ifih1,Isg15,Usp18,Icam1,Pml,Dhx58,C1ra,Rsad2,Hspa2,Fchsd2,Arid5a,Stat5a,Tnf,Phf11b,P4ha2,Sp110,Acp2,Cxcl10,Ak4,Ldha,Ripk2,Herc6,Wars,Stoml1,Scn1b,Slc2a6,Fzd5,Snx10,Pde4b,Slc31a2,4930523C07Rik,Phf11c,Tap1,Atp2b4,Cd80,Phf11a,Adar,Rbms2,Rtp4,Phactr4,Dtnb,Il18bp,Bnip3,Jun,Gadd45b,Klf3,Adam19,Tnfaip2,Fscn1,Rbms1,Cflar,Gpd2,Mmp25,Adrb2,Phf11d,Oasl1,Socs3,Dram1,Tdrd7,Psme2,Plscr1,Trim21,Lap3 |
| 2.142e-27 | -61.41 | GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP | 181 | 66 | 15632 | 1249 |
Ppp1r14b,Slc7a11,Irf4,Tor1aip2,Stap1,Rai14,Cox17,Vcan,Mllt6,Nfkbiz,Lrp8,Aldh1b1,Plau,F10,Cdc42ep2,Zbp1,Ahr,Abtb2,Dcun1d3,Procr,Zfp36,Nfkbib,Hivep3,Casp7,Ifi35,Denr,Rgs1,Cd300lf,Kdr,Nfil3,Txnrd1,Arid5a,Cd40,Batf2,Ccdc86,Ubtd2,Rnf24,Glipr2,Stk40,Slc30a4,Socs1,Slco3a1,Cd83,Batf,Traf5,1600014C10Rik,Daxx,Dusp6,Flrt2,Fubp1,Rrs1,Mmp13,Inhba,Ripk2,Fndc3a,Ptgs2,Map3k8,St7,Cxcl1,Vcam1,Il1rn,Cmklr1,Ralgds,Fmnl2,Rcl1,Tfec |
| 2.172e-27 | -61.39 | negative regulation of multi-organism process | biological process | GO:0043901 | 232 | 70 | 20694 | 1406 |
Mul1,Oasl2,Fam111a,Slpi,Oas1a,Arg2,Htra1,Isg20,Samhd1,Nmi,Smpdl3b,Nfkbil1,Trim26,Plscr1,Trib1,Tnfaip3,Oas1g,Adar,Tlr2,Sqstm1,Timp1,Itgav,Acod1,Stat1,Zc3hav1,Lgals9,Trim13,Irf8,Dhx58,Tap1,Isg15,Zc3h12a,Fgl2,Jun,Shfl,Rsad2,Mapkbp1,Tnf,Oasl1,Eif2ak2,Nlrc5,Apobec3,Ccl4,Trim56,Il10,Pml,Ccr1,Parp14,Trafd1,Parp10,Hdac1,Slamf8,Prdm1,Oas3,Myd88,Nod2,Ifnb1,Trim14,Ccl5,Serpinb9,Tap2,Trim21,Resf1,Clec2d,Il12b,Oas1b,Ifitm1,Irak3,Ptpn2,Zfp36 |
| 2.848e-27 | -61.12 | GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | 187 | 67 | 15632 | 1249 |
Slc7a2,Pik3r6,Daam1,Maff,Wars,Icosl,Sap30,Il2rg,Adora2b,Ripk2,Zc3h12a,Ptges,Sec24b,Stip1,Lacc1,Clic4,Cldnd1,Irak2,Vcam1,Tank,Traf2,N4bp1,Cers6,Pnp2,Rffl,Ubtd2,Agtrap,Sphk1,Cd38,Stau1,Sav1,Heatr6,Gbp7,Casp4,Rel,Rnf31,Ppp1r15b,Kctd12,Psme2,Rab20,Irf1,Filip1l,C3,Ptgir,Kpna3,Dgkh,Sema4c,Ebi3,Rap2c,Whamm,Trip10,Znfx1,Psmd10,Rab32,Gramd1a,Parp9,Tra2a,Optn,Mllt6,Ctsc,Ciapin1,Nfkbiz,Slfn5,Aff1,Spred1,Klf7,Il15 |
| 3.108e-27 | -61.04 | GSE17721_LPS_VS_CPG_12H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_12H_BMDC_UP | 182 | 66 | 15632 | 1249 |
Wdfy1,Serpine1,Cd86,Samsn1,Tshz1,Snx10,Sp110,Sec24b,Keap1,Il15ra,Plat,Tnfsf10,Il1rn,Vcam1,Serpinb9,Cxcl10,Tapbpl,Ak4,Grina,Dnaja2,Tlr3,Ythdf1,Hdac1,Gbp4,Gbp9,Tnfsf8,Batf2,1110038F14Rik,Rab21,Tpst1,Birc2,Tcf4,Hspa1a,Arid5a,Timp1,Lrp4,Gypc,Insl6,Ifit2,Prpf38a,Plagl2,Cd83,Slco3a1,Upp1,Pml,Itga4,Timeless,Trim21,Csf1,Casp4,Ogfr,Mov10,Ifit3,Lrrc8c,Gfi1,Actb,Polr2g,Ifit3b,4932438A13Rik,Psip1,Plac8,Crbn,Samhd1,Cd80,Il15,Tpx2 |
| 4.155e-27 | -60.75 | STK33_SKM_UP | MSigDB lists | STK33_SKM_UP | 249 | 78 | 15632 | 1249 |
Il1b,Tfec,Kitl,Nfxl1,Bcl2a1a,Arid5b,Fcho2,Dusp5,Rtn1,Hmox1,Rnf19b,Tlr1,Arl5b,Ifi208,Phlda1,Gpr132,Btg2,Plk2,Daam1,Cd86,Nampt,Junb,Rhoc,Gbp2,Fgr,Il1a,Kmo,Upp1,Mxd1,Bcl2a1d,Errfi1,Fgl2,Dusp8,Itgb8,Ifi205,Ifi209,Ifi213,Dusp1,Tnf,Klf6,Cdkn1a,Gbp2b,Fam20c,Tnfaip2,Rgs1,Ccl4,Trib1,Dnajb4,Irf1,Ifi204,Cpeb4,Ifi203,Stx6,Rnf19a,Zfp36,Ifi211,Mndal,Pid1,Mfap3l,Olr1,Ifi207,Gng11,Rnd3,Plau,Il15,Ifi214,P2ry14,Palld,Tlr6,Egr1,Nfkbiz,Kcnj2,Nlrc4,Fos,Slc7a11,Sqstm1,Bcl2a1b,Nfkbia |
| 4.495e-27 | -60.67 | GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_DN | 183 | 66 | 15632 | 1249 |
Stat2,Usp18,Ifih1,Marcksl1,Aim2,Prrg4,Cd38,1600014C10Rik,Oas3,Ifit2,Phf11b,Cers6,Bcl2a1d,Rsad2,D1Ertd622e,Rab9,Itgb8,Nr4a3,Herc6,Naa25,Cmpk2,Bcl2a1a,Plat,Tnfsf10,Irak2,Cd274,Cnp,Irf7,Slc31a2,Pde4b,Ifit1bl2,Gch1,Ccl5,Wars,Oas2,Tbc1d13,Parp12,Nfkbiz,Atf3,Usp25,Phf11c,Il15,Slamf7,Phf11a,Eif2ak2,Nlrc5,Ifit1bl1,Sod2,Bcl2a1b,Cnot4,Samd9l,Phf11d,Ifit3b,Dram1,Ebi3,Hmgcs1,Cflar,Whamm,Tnfaip2,Adam19,Ccl4,Ifit3,Abtb2,Birc3,Trim56,Akt3 |
| 5.651e-27 | -60.44 | cell activation | biological process | GO:0001775 | 599 | 119 | 20694 | 1406 |
Prdx1,Pilrb1,Milr1,Ifna6,Nck1,Ikzf1,Acvrl1,Nampt,Fcgr2b,Rasgrp1,Syk,Ubash3b,Stxbp1,Rsad2,Jun,P2ry12,Tcf4,Cx3cl1,Tnf,Bcl6,Psmb10,Treml2,Malt1,Cd74,Cd180,Tlr1,Il12b,Cd40,Stxbp3,Jmjd6,Ifnb1,Notch2,Icam1,Rgcc,Ccl5,Egr1,Spn,Pik3cd,Plek,Tnfsf9,Sema4a,Cd86,Nfkb2,Atm,Il6,Bcl2a1d,Plcl2,Slc7a2,Ifna1,Axl,Hhex,Il1b,Tlr3,Ifnar1,Gja1,Itgav,Slc7a11,Relb,Lyn,Nr4a3,Clcf1,Prkce,Ahr,Pf4,Tlr9,Evl,Slamf8,Batf,Irf1,H60b,Cx3cr1,Tnfsf4,Ptger4,Azi2,Ifna2,Stat5a,Adora2a,Gadd45g,Fcgr4,Irf4,Ptpn2,Fzd5,Fas,Il15,Stat3,Icosl,H2-Ab1,Casp1,Fpr2,Stx11,Il18rap,Tnfsf8,Dock10,Ptprj,Raet1e,Klrk1,Ebi3,Ifna5,Cxcl10,Ifna4,Ripk2,Batf2,Dnase1l3,Pou2f2,Il18,Fgl2,Swap70,Itgal,Rhoh,Timp1,Tlr6,Jak2,Lcp2,Tnfaip3,Ripk3,Clec4d,Tlr2,Gpr18,Clec4e |
| 5.863e-27 | -60.40 | GSE1432_1H_VS_6H_IFNG_MICROGLIA_DN | MSigDB lists | GSE1432_1H_VS_6H_IFNG_MICROGLIA_DN | 189 | 67 | 15632 | 1249 |
Prrg4,Ifih1,Relb,Mvp,Gbp2,Phf11b,Cd40,Rhbdf2,Psmb9,Ifi44,Rnf24,Dennd1b,Stat3,Rsad2,C1ra,Cers6,Nfkbie,Scyl2,Herc6,Slamf8,Tnfsf10,Sp110,Keap1,Il15ra,Rgl1,Vps54,Rrs1,Irf7,Ascc3,Nmi,Parp12,Wars,Rapgef2,Usp25,Ddx60,Phf11a,Adar,Slamf7,Ciita,Il15,Phf11c,Tap1,Rnf114,Dnaja1,Nod2,Stat1,Casp7,Max,Mthfd2,Phf11d,Aida,Rcn1,Chd9,Tnfaip2,Jak2,Dr1,Rbms1,Birc3,Psmb8,Lap3,Casp4,C1rl,Psme2,Plscr1,Alas1,Zc3h7a,Tdrd7 |
| 7.046e-27 | -60.22 | BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX | MSigDB lists | BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX | 26 | 25 | 15632 | 1249 |
Ifit2,Ifi213,Ifit1bl1,Ifi205,Ifi209,Psmb9,Psmb10,Isg15,Ifi214,Ifi207,Psmb8,Ifit1bl2,Irf7,Mndal,Ifit3,Ifi208,Ifi211,Ifi203,Oas1a,Oas1g,Stat1,Ifi35,Ifit3b,Ifi204,Irf1 |
| 7.061e-27 | -60.22 | GSE3982_CTRL_VS_LPS_48H_DC_DN | MSigDB lists | GSE3982_CTRL_VS_LPS_48H_DC_DN | 179 | 65 | 15632 | 1249 |
Gadd45g,Nqo1,Stap1,Sqstm1,Ifit1bl1,Nfkbia,Gadd45b,Cd80,Slamf7,Rnd3,Atf3,Tmem176a,Oas1a,Psme2,Alas1,Isg20,Csf1,Sik3,Tnfsf14,Rel,Ifit3,Prkar2b,Abcc1,Tnip1,Ccl4,Fscn1,Cflar,Ifit3b,Sema4a,Trib1,Ppa1,Filip1l,Cd200,Dram1,Rsad2,Tlk2,Ifi44,Fchsd2,Rhbdf2,Txnrd1,Sp140,Dusp1,Tsku,Tnfaip3,Cd38,Cutc,Isg15,Slco3a1,Stat2,Atp11a,Aim2,Marcksl1,Parp12,Tbc1d13,Inhba,Serpine1,Irf7,Ccl5,Ifit1bl2,Plaur,Cxcl10,Il12b,Pim1,Oas1g,Rnf19b |
| 7.940e-27 | -60.10 | regulation of locomotion | biological process | GO:0040012 | 1011 | 165 | 20694 | 1406 |
Atm,Dusp1,Acvr1b,Itga5,Hif1a,Abr,Syne2,Jag1,Cnn2,Ptgs2,Spn,Rapgef2,Plk2,Thbs1,Pik3cd,Sema4a,Adora2b,Bmp2,Rap2c,Rhof,Itgav,Lmo4,Lyn,Cav1,Pcx,Sell,Tnfrsf14,Prkce,Nr4a3,Myadm,Tnfsf14,Mdm2,Sirt1,Mmp9,Pdgfc,Fubp1,Trim13,Lgals9,Cd274,Ppp2r3a,Il1b,Cited2,Kdr,Ccl4,Jun,Rffl,Sod2,P2ry12,Kitl,Il1a,P2ry2,Zswim4,Cx3cl1,Nck1,Met,Angpt1,Myd88,Acvrl1,Ccr1,Spata13,Trim56,Pml,Abcc1,Sdc4,Ccl12,Rras2,Cd40,Igf1r,Clic4,Fgr,Cxcl14,Irs2,Sinhcaf,Rgcc,Icam1,Rabgef1,Egr1,Ccl5,Cd74,Il1rn,Rnd1,Agrn,Pdgfb,Spred1,Ptafr,Flt1,Cxcl10,Lrch1,Lpar1,Mtus1,Trim26,Map4k4,Sema3c,Src,Stat3,Gcnt2,Fpr2,Dock10,Map2k1,Ptprj,Crkl,Sphk1,Spint2,Jak2,Timp1,Trib1,Hmox1,Tlr2,Ripk3,Cd200,Gpr18,Ddx58,Rnd3,Il18,Zc3h12a,Swap70,Sele,Akt3,Notch1,Chmp4b,Ptger4,Vegfc,Plpp3,Mecp2,Bst1,Cmklr1,Stat5a,Glipr2,Adora2a,Pdpn,Evl,Slamf8,Igsf8,Plau,Ccl2,D1Ertd622e,Dach1,Cx3cr1,Tnfsf4,Acvr1,Sema4c,Edn1,Stap1,Trim21,Flrt2,Nod2,Pla2g7,Spry2,Col18a1,Serpine1,Tmsb10,Carmil1,Dock4,Fas,Csf1,Itga4,Myc,Svbp,Ptpn2,Pdgfrb,Mmp14,Ptk2,Prkx,Rhoc,Prag1 |
| 8.375e-27 | -60.04 | GSE17721_0.5H_VS_8H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_8H_POLYIC_BMDC_DN | 190 | 67 | 15632 | 1249 |
Cenpe,Rnf114,Hmga1,Ctsc,Irgm2,Mmp14,Ift57,Atf3,Etv3,Rnd3,Rbm43,Zbp1,Slc28a2,Psmb8,Ccne1,Ppp1r15b,Cav1,Irf8,Lmo4,Lap3,Nos2,Cep350,Cnn3,St3gal5,Hat1,Ebi3,Endod1,Ddx4,Arf4,Cacna1d,Ldlr,Esd,Cdkn1a,Vrk2,Homer1,Itpr1,Nr3c1,Hdac1,Dhx58,Upp1,Tab2,Cd164,Mcmbp,Mdfic,Plagl2,Rgl1,Slfn4,Vps54,Igsf8,Rab10,Rilpl1,G3bp2,Pde7b,Tbc1d13,Ptprj,Smc5,Chic2,Map3k8,Il1rn,Slfn3,Gtpbp2,Kitl,Ralgds,Gca,Vegfc,Slc37a3,Hcar2 |
| 9.320e-27 | -59.94 | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN | MSigDB lists | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN | 185 | 66 | 15632 | 1249 |
Cdkn1a,Abcc1,Agpat4,Tnip1,Ccl4,Mafg,Ier3,Pim2,C3,Mmp9,Ebi3,Stat4,Ccrl2,Pla2g7,Gna15,Tnfsf14,Tnfrsf1b,Birc3,Slamf7,Pfkfb3,Sdc4,Gmppb,Ccl22,Dusp4,Nqo1,Gadd45g,Il6,Ets2,Trip10,Rhof,Dock4,Slc7a11,Ccl12,Ppp1r14b,Sod2,Hivep2,Keap1,Il1b,Zhx2,Serpinb2,Acsl5,Cxcl1,Il1rn,Clec5a,Pim1,Ptgs2,Slc43a3,Ak4,Zc3h12a,St3gal1,Cxcl2,Maff,Inhba,Slc7a5,Atp6v1d,Txn1,Nampt,Rgl1,Crim1,Traf1,Sphk1,Upp1,Psma6,Nfkbie,Rhoq,Txnrd1 |
| 9.320e-27 | -59.94 | GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_DN | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_DN | 185 | 66 | 15632 | 1249 |
Slfn8,Irgm2,Ift57,Psip1,Pnpt1,Tap1,Zc3hav1,Olr1,Slc28a2,Foxp4,Tmem176b,Plagl1,Ccnd2,Plscr1,Xaf1,Slc39a14,Ptch1,Itgal,Asf1a,Hcls1,Col27a1,Znrf1,Cdkn1a,Plekhn1,C3,Mmp9,Stat1,Casp7,Mthfd2,Gpd2,Rcn1,Rnf145,Ms4a6d,Pnp2,Gpr68,Stk40,Psma6,Ctu1,Txnrd1,Parp8,Acpp,Arhgef3,Mthfr,Nupr1,Lrch3,Prdm1,Rnd1,Psmb10,Ddx58,Phlda1,Sap30,Nrp2,Rab10,Parp12,Plk2,Cd86,Ppm1k,Ikbke,Slfn9,Il1rn,Dnaja2,Tlr3,Gpr85,Ttc39b,Clec5a,Usp42 |
| 1.105e-26 | -59.77 | regulation of developmental process | biological process | GO:0050793 | 2711 | 325 | 20694 | 1406 |
Tnfrsf1b,Plac8,Nlrp3,Akt3,Rgs14,Bcor,Timp1,Stat1,Jak2,Flrt3,Errfi1,Rap1gap2,Sphk1,Crkl,Maff,Vasn,Cysltr2,Inhba,Pgk1,Trib1,Tnfaip3,Egr3,Bcl2l11,Hck,Stat3,Src,Sema3c,Gpr68,Nr3c1,Hcls1,Eif4g2,Map2k1,Lst1,Stat2,Mafg,Cxcl10,Flt1,Arg2,Lif,Pdgfb,Gpc1,Lpar1,Pdgfrb,Cebpd,Ptpn2,Ccl8,Myc,Myo10,Pde5a,Htr2a,Prag1,Clec2d,Ccl9,Kdm5b,Rac3,Prkx,Zeb1,Ptk2,Dync1i2,Ntng2,Csf3r,Sipa1l1,Triobp,Rhoq,Spen,S1pr2,Ifrd1,Klf2,Csf1,Ociad1,Nupr1,Il15,Spry2,Ccl2,Slamf8,Pf4,Adrb2,Tlr9,Nfkbia,Sdc2,Ezr,Znrf3,Socs3,Mecp2,Eef1e1,Tulp3,Vegfc,Hopx,Pdpn,Rhou,Socs1,Ap3b1,Pnpt1,Eif2ak2,Glipr2,Stat5a,Cxcl1,Mdm2,Il1b,Isg15,Hmga2,Ppp2r3a,Trib3,Fubp1,Itgav,Gja1,Rhof,Tlr3,Hk2,Nfkbiz,Ccnd1,Tnfsf14,Keap1,Cdk5r1,Tnfsf9,Thbs1,Lhx2,Plk2,Cd34,Ctsc,Bmp2,Ddhd1,Sema4a,Acvr1b,Hif1a,Itga5,Il6,Kdm4a,Jag1,Lox,Il2rg,Cflar,Ednrb,Pdlim7,Bcl6,Bnip3,Gdf15,Il12b,Rnd1,Agrn,Il1rn,Cgas,Cnot4,Cst7,Mark2,Cxcl14,Mosmo,Srgn,Egr1,Rgcc,Sinhcaf,Zhx2,Notch2,Acvrl1,Serp1,Met,Nck1,Tmem176a,Katna1,Etv5,Cdkn1a,Nampt,Casp8,Plaat3,Dusp6,Kdr,H2-Aa,Ubash3b,Cx3cl1,P2ry2,Kitl,P2ry12,Zc3h12a,Fgl2,Il18,Tomm70a,Scarf1,Rhoh,Notch1,Trip10,Gfi1,Foxp4,Rnd3,Pim1,Tlr2,Hmox1,Gcnt2,Csf3,Cdc42ep2,Map4k4,Ldlr,Ccne1,Hap1,Jarid2,Scn1b,Tmem178,Spred1,Cxcl9,Lrp4,Hlx,Ripk2,Mul1,Ctla2a,Zfp36,Irak3,Rhoc,Itgb8,Sav1,Ccr3,Mmp14,Phldb1,Edn1,Stap1,Sema4c,D16Ertd472e,Lrp8,Fas,Serpine1,Tmem176b,Carmil1,Nfkbid,Flrt2,Plau,Irf1,Cdc42ep4,Phlpp1,Hdac1,Fmnl2,Ust,Acvr1,Tnfsf4,Cx3cr1,Rab21,Il10,Cenpe,Lnpk,Cmklr1,Kif3c,Abcb1a,Mov10,Ptger4,Tspo,Ehd1,Mmp9,Sirt1,Fam20c,Pik3r6,Cd83,Cd274,Hhex,Lgals9,Il15ra,Axl,Ptch1,Lmo4,Itpr1,Dbnl,Ahr,Myadm,Pbx1,Clcf1,Klf7,Cav1,Lyn,Il4ra,Kremen1,Cd38,Rapgef2,Cd86,Adgrl2,Casz1,Cyfip1,Ptgs2,Mmd,Fos,Abr,Malt1,Junb,Sec24b,Aida,Oas2,Parp3,C3,Cd74,Phip,Wars,Msr1,Mtdh,Fgr,Ankrd17,Nlgn2,Mycl,Igf1r,Rbl1,Cd40,Ccl5,Icam1,Jdp2,Kat2b,Ifnb1,Col4a2,Noct,Ikzf1,Il27,Pilrb1,Prdm1,Rasgrp1,Ccl12,Pml,Brwd3,Ccr1,Bambi,Syk,Pde3b,Cited2,Zswim4,Tnf,Ifi204,Il1a,Ccl3,Daxx,Jun,Tcf4,Sod2,Fzd1 |
| 1.171e-26 | -59.71 | VERHAAK_AML_WITH_NPM1_MUTATED_UP | MSigDB lists | VERHAAK_AML_WITH_NPM1_MUTATED_UP | 170 | 63 | 15632 | 1249 |
Cd14,Tnfaip3,Hck,Mvp,Aim2,Fgr,Slc15a3,Sat1,Bcl2a1d,Fgl2,Casp1,Slc16a3,Tnf,Bcl6,Tnfsf10,Serpinb2,Thbs1,Nfkb2,Cxcl1,Bcl2a1a,Il1b,Abcc4,Pf4,Plaur,Hmox1,Cxcl10,Fpr1,Ptafr,Slc2a6,Phlda1,Cxcl2,Wars,Gch1,Gdf15,Ccr1,Nampt,Plek,Fcgr4,Snx10,Cd86,Pilra,Hk3,Tmem176b,Dmxl2,Peli1,Il6,Pla2g4a,Kcnj2,Vcan,Bcl2a1b,Sod2,Nfkbia,Cx3cr1,Ets2,Tnfaip2,Ccl4,Prkar2b,Trem1,Acsl1,Ier3,Trib1,Tmem176a,Jag1 |
| 1.336e-26 | -59.58 | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_UP | 186 | 66 | 15632 | 1249 |
Slc31a2,Ifit1bl2,Osm,Hopx,Tap2,Cnp,Cd86,Thbs1,Pf4,Sec24b,Rcan1,Pnp2,Gbp9,Gbp4,Tapbp,Ifit2,Cd40,Rgs14,Swap70,Psmb9,1600014C10Rik,Myd88,Cd164,Pml,Lrch3,Itga4,Hlx,Psmb10,Dtx3l,Ksr1,Rasgrp1,S100a8,Ubr4,Cflar,Actb,Ptk2,Ebi3,Tlr2,Parp11,Katna1,Samd9l,Il18bp,Trmt1l,Agrn,Hivep2,Nfkbia,Nr4a1,Plac8,Gsdmd,Nlrc5,Ifit1bl1,Casz1,Cyfip1,Spic,Msr1,Rbm43,Zbp1,Clec4e,Samhd1,Enpp4,Nfkbiz,Arrdc4,Papss2,Pttg1,Coa5,Ubash3b |
| 1.578e-26 | -59.41 | membrane-bounded organelle | cellular component | GO:0043227 | 10800 | 924 | 20747 | 1409 |
Crlf3,Rasgrp1,Mcoln2,Lnpep,Nfkbie,Ptch1,Nek6,Med21,Isg15,Grina,Rnaset2b,Lyn,Gpd2,Sec24b,Daxx,Ext1,Pla2g4a,Sgk3,Stat4,Ap3b1,Phf11d,Gbp7,Hmox1,Stat1,Slc25a25,Gem,Tap1,Adrb2,Prkx,Abcc1,Slc16a1,Rars,Caml,Flt1,Zbtb5,Ripk2,Syk,Btg2,Arl4a,Kcnj2,Bcl6,Tapbp,Fzd5,Mitd1,Hat1,Vcam1,Oas1g,Cacybp,Tor3a,Ehd1,Ifi213,St3gal1,Psme1,Perm1,Dock10,Gsap,Socs1,Whamm,Foxp4,Rsbn1,Isg20,Anp32a,Irgm2,Gpr18,Plekha2,Ncoa5,Dusp16,Spire1,Tmtc2,Nfxl1,Prdm1,Arl5c,Mtfr2,Cdc42ep2,Rab9,Slc15a3,H2-Aa,Ccne1,Rcn1,Ldha,Sinhcaf,Pbx1,Dnaja2,Slamf7,Rhoc,Itga5,Trim36,Mppe1,Slc30a1,H3f3b,Oas3,Nod2,Chd9,Rsad2,Irgm1,Rab21,Plekhn1,Nfkbia,Dock4,Tut7,Kat2b,Mfap3l,Etv6,Plekhf2,Msr1,Tgs1,Trim13,Pgap2,Mcmbp,Ikbke,Adap2,Cd274,Agpat4,Rfx5,Nck1,Rab10,Ezr,Milr1,Vezt,Tiparp,Rap2c,Traf2,F10,Hdac1,Tyk2,Slc25a12,9130023H24Rik,Hsd17b7,Ccl2,Mx2,Map2k4,P2ry13,Ccnj,Crbn,Pdk3,Prpf4,Lpar1,Slfn5,Ier3,Asap3,Ifit3b,Asah2,Dmwd,Nfkbiz,Nr3c1,Maff,Plod3,Phyh,Usb1,Rnf14,Ciapin1,Stxbp3,Ifi207,Lipg,Rab32,Gadd45g,Mtcp1,Myc,Tnks1bp1,Arid5a,Mov10,Sema4a,Gadd45b,Il15ra,Nfil3,Thbs1,Pdpn,Mecp2,Rnd3,Pgs1,Stoml1,Ifi209,Plat,Ppfia3,Rgs3,Ociad1,Cycs,Snx10,Lacc1,Cdyl2,Junb,Fignl2,Klf8,Ifi214,Mdn1,Cx3cr1,Flrt3,Fam111a,Psmb6,Dcp2,Dmxl2,Tle3,Nt5c3,Phlda1,Ppp1r15a,Vcpip1,Oas2,Casp3,Rhou,Plod2,Rhbdf2,Wars,Grk3,Marf1,Chic2,Fam20c,Rab11fip1,Gk,Kmt5a,Acod1,Samsn1,Znrf1,Hmgn3,Rgcc,Gbp9,Bcorl1,Slc29a3,Ifi204,Slc16a3,Plekha5,Mthfd2,Cd14,Jmjd6,Mark2,Zfp800,Sh3bgrl2,Ifit3,Stap1,Noct,Trim14,Pde4b,Arf4,Cd164,Phlpp1,Ranbp2,4930453N24Rik,Stat2,Stat5a,Shfl,Olr1,Itpkc,Rel,Spic,Hck,Nfkbib,Mdm2,Gbgt1,Rilpl1,Usp12,Atp10a,Nr4a3,Lipe,Klf7,Tnfaip3,Kif3c,Tnf,Trip10,Nos2,Ero1l,Usp25,Notch2,Ptger4,Dram1,Ahrr,Hsd17b12,Aldh1b1,Rnf145,Ets2,Atp11a,Golga3,Ifih1,Hivep2,Dusp4,Cacna1d,Rnf139,Polr2g,Nfkb2,Psmd10,Pnp2,Ptk2,Tor1aip1,Fgr,Mtdh,Dach1,Rcan1,Adam19,Samd9l,Gbp2b,Uchl1,Pttg1,Hivep3,Ell2,Themis2,Zfp319,Trim21,Parp10,Cd86,Tap2,Calcrl,Pf4,Tlk2,Ifi35,Mxd1,Gm4841,Dennd6b,Batf2,Psd,9930111J21Rik1,H2-Q7,Htr2a,Vrk2,Pikfyve,Zfp36,Serpinb9,Cers6,Ifi208,Ifi203,Ddit4,Coa5,Lcn2,Mt2,Fndc3a,P2ry2,Psma6,Ep400,Serpina3g,Zup1,Ccnd2,Hcls1,Cdkn2d,Cenpe,Palld,Rnf114,Dek,Plaat3,Dpy19l1,St3gal6,Edn1,Tent2,Tal2,Nfkbid,Alas1,Dhrs9,Socs7,Cdkn1a,Sde2,Ak4,Cd40,Psip1,Etv3,Spata13,Hhex,Pik3r5,Atf3,Gfi1,Pdgfrb,Tpx2,Ier2,Jarid2,Ubr4,Zc3h12a,Parp14,Acsl5,Oas1b,Rab19,Bbx,Ahsa1,Myo10,Extl2,Osbpl3,Mapkapk2,Aim2,F11r,Tpst1,Sla,Tra2a,Ddx4,Irf7,Xaf1,Cited2,Slc4a7,Ubash3b,Psmb10,Sbds,Treml4,Irf4,Nampt,Dnajb4,Pcgf5,Ifitm1,Hspa1b,Slc39a13,Flnb,Ccdc86,Jun,Cyth3,Zeb1,Cdyl,Uba7,Klf2,Etnk1,Noc4l,P4ha2,Ccr3,Cop1,Casp2,Casp7,Pdgfc,Pou2f2,Kdm5b,Swap70,Gm5431,Fos,Esd,Tasor2,Lox,Tspo,Pml,Hsph1,Top3a,Tma16,Zfp40,Igf1r,Tbc1d1,1600014C10Rik,Sap30,Txnrd1,H2-Eb1,Egln3,Egr1,Me1,Nmral1,Shisa3,Nr4a1,Rbms1,Stk40,Kdm6b,Nox1,Phf11b,Dusp1,Ikzf1,Parp12,Fcho2,Ifnar1,Bfar,Phf11a,H2-Ab1,Lhx2,Ralgds,Mmp14,Herc6,Cnot4,Spred1,Itga4,Trim30a,Hk2,Apba1,Rapgef2,Stx6,Gpc1,Cdc42ep4,Timeless,Tomm70a,Adar,Prdx5,Mt1,Flrt2,Tent4a,Uaca,Prpf38a,Plagl1,Spen,Rbpms,Tdrd7,Katna1,Mier3,Sesn3,Wdfy1,Oas1a,Birc2,Minpp1,Naa25,Micall2,Smc5,Hopx,Slfn9,Ap3m2,Sod2,Dusp2,Serp1,Dbnl,Carmil1,Clcn5,Rabgef1,Ncoa7,Kdr,P2ry12,Bcl2l11,Morc3,Zhx2,Slc31a1,Sgms2,Fam241a,Ksr1,Plekhg1,Mrpl52,Mdfic,Casp8,Trmt1l,Actb,Psme2,Tlr1,Car13,Ktn1,Bcl9,Irak2,Idi1,Plac8,H2-Q4,Kdm4a,Tmem176b,Dusp8,Cd74,Zfp513,Cst7,Tmem178,Cgas,Gja1,Hmga2,Pnpt1,Pfkfb3,Gm4951,Lap3,Pou3f1,Atp13a1,Mmd,Gpr85,Slc44a1,Ppm1k,Lnpk,Ago3,Rbbp8,Cav1,Csrp1,Stat3,Dck,Hk1,Plk2,Tlr9,Rbms2,Plpp3,St3gal3,Hmga1,Ust,Eif2ak2,Pmaip1,Prnp,Ric1,Irak3,Ppp2r5a,Trim26,Sema4c,Zfp945,Nr1h3,Bcl2a1a,Pcx,Errfi1,Tulp3,Itgav,Phf6,Smg7,Tet2,Stau1,Il1b,Trip13,Mafg,Casz1,Pde3b,Ifit2,Mul1,Sco1,Cutc,Aftph,Fcgr2b,Prag1,Sp140,Higd1a,Txn1,Cmpk2,Mndal,Gramd1a,Cebpd,Igf2bp2,Taf4b,Piezo1,Myd88,Fam53c,Eef1e1,Bmp2,Itpr1,Mosmo,Ppp4r2,Peli1,Ift57,Egr3,Cep350,Dst,Hk3,Rnf34,Crkl,Hlx,Cd38,Zyx,Ogfr,Nlrp3,Dnaja1,Bnip3,Syne2,Sirt1,Rapgef5,Il15,Ifi47,Rtn2,Clic4,Dnase1l3,Chmp4b,Wdr43,Slc7a5,Trib3,Cnp,Mpp7,Armcx6,Slfn1,Cdk5r1,Spry2,Csrnp1,Slc25a37,Kif9,F830016B08Rik,Dr1,Ptpn2,Degs2,Filip1l,Rcl1,Dtx2,Vps54,Dgkh,B4galt4,Atm,Prdx1,Mtus1,Gdf15,Asf1a,Ikbkg,Phf11c,Irf8,Mefv,Tmem123,Maml2,Abtb2,Upp1,Parp11,Tcf4,Dcp1a,Myo1b,Dyrk2,Dync1h1,Spn,St3gal5,Keap1,Src,Gsr,Eya4,Tlr3,Nlrc5,Pmepa1,Zmynd15,Gmppb,Pim1,Kmo,Tgfbi,Rhof,Il1rn,Arid4a,N4bp1,Rgs14,Mmp13,Lrrc8c,Evl,Zbp1,Mcm10,Riox2,Sav1,Acpp,Tshz1,Fut8,Acsl1,Inpp5b,Gtpbp2,Triobp,Hp,Dnajb2,Tnip1,Slc9a1,Ptgs2,Cd34,Tor1aip2,Mcm6,Aebp2,Birc3,Slc2a1,Fchsd2,Max,Rffl,Ednrb,Srgn,Acp2,Sphk1,Chst11,Marcks,Serpine1,Prdm9,Slc25a22,Hinfp,Tlr2,Htr2b,Mamld1,Malt1,Sec24a,Atp11b,Apobec3,Usp18,Rtn1,Mgat1,Igtp,Usp31,Nfkb1,Nupr1,Setdb2,Plscr1,Tlr6,Slc49a4,Rpgrip1l,Notch1,Slc7a11,Abcc4,Serpinb6b,Phip,Glrx,H2-Q6,Akt3,Slc39a4,Cpeb4,Stxbp1,Dusp14,Mapkbp1,Clic5,Acp5,Iigp1,Tmem67,Ifi211,Ifrd1,Pdlim7,Sqstm1,Ahr,Parp9,Tcea1,Gbp2,Mthfd1l,Stard7,4932438A13Rik,Slc48a1,Ppp1r15b,Nfkbil1,Aoah,Ascc3,Cox18,Ccnd1,Sertad3,Relb,Ifi205,Rnaset2a,Helz2,Icam1,Armc8,Rnf24,Pdss1,Med13,Gcnt2,Oasl1,Hspa1a,Slc31a2,Pkp4,Hilpda,Pigv,Smox,Ass1,Dennd1b,Lpcat2,Hif1a,Slc30a4,Fam162a,Fosb,Glipr2,Zc3hav1,Aff1,Apaf1,Kpna3,Mcm9,Optn,Rmdn3,Tgtp1,Fnbp1l,Tapbpl,P4ha1,Scyl2,Rubcnl,Rnf19b,Cox17,Sik3,Slc37a3,Casp1,Map2k1,Zfp281,Dusp5,Brd2,Klf6,Phlpp2,Trib1,Fabp7,Arid5b,Tgtp2,Nmi,Gsdmd,Tfec,Klf3,Fas,Il4i1,Rap1gap2,Rai14,Gbp8,Arrdc4,Bcl2a1d,Hap1,Irf2,Cenpj,Samhd1,Cept1,Jdp2,Fubp1,Nsd3,Psmb8,Adhfe1,Plk3,Rab3ip,Ube2e1,Ccng2,Snx2,B3gnt5,Parp3,Snn,Vasn,Cpd,Mafk,Bcor,Ccdc88b,Ripk3,Rab20,Arg2,Wdr59,Oasl2,Irf1,Psmb9,Ankrd17,Lgals9,Ldlr,Ptges,Yju2,Rbl1,Magohb,Bcl2a1b,Gm12185,Clcn7,Cxcl14,Agtrap,Mvp,Dse,Sh3bp4,Resf1,Stx11,Batf,Arl5b,Mycl,Plagl2,Tab2,Gch1,Marcksl1,Casp4,Rnd1,Rrs1,Hspa2,Tnfrsf1b,Egr2,Prkce,Gbp3,Sp110,Rrbp1,Znfx1,Jak2,Fam72a,Ciita,Nxf1,Trim12c,Dtx3l,Snapc1,Brwd3,Ch25h,Stip1,AA467197,Ctsc,Sp100,Mx1,Etv5,Ctu1 |
| 1.618e-26 | -59.39 | positive regulation of intracellular signal transduction | biological process | GO:1902533 | 933 | 156 | 20694 | 1406 |
Ptk2,Ddx60,Prag1,Ccl9,Gadd45g,Htr2a,Ccl8,Pde5a,Plagl2,Pdgfrb,Ptpn2,Fzd5,Nod2,Spry2,Nupr1,Csf1,Sema4c,Edn1,S100a8,Cx3cr1,Map2k4,Glrx,Adrb2,Tlr9,Phlpp1,Slc9a1,Ccl2,Glipr2,Map3k8,Eif2ak2,Ccl7,Ptger4,Eef1e1,Zc3hav1,Akt3,Notch1,Scimp,Irak2,Clec4n,Il18,Itgal,Zc3h12a,Rictor,Traf5,Ripk3,Tlr2,Cysltr2,Gpr18,Crkl,Sphk1,Marco,Tlr6,Jak2,Casp1,Fpr2,Hap1,Map2k1,Ptprj,Hcls1,Map4k4,Gcnt2,Bcl2l11,Csf3,Src,Peli1,Tnfsf15,Tifa,Ripk2,Lpar1,Mul1,Wdr59,Tab2,Spred1,Lif,Pdgfb,Traf2,Flt1,C3,Cd74,Tlr1,Gadd45b,Spred3,Traf3ip2,Cgas,Il1rn,Gdf15,Rnf31,Cd14,Malt1,Nod1,Notch2,Icam1,Ccl5,Igf1r,Cd40,Mtdh,Fgr,Ankrd17,Map3k6,Nox1,Casp8,Ccr1,Pim2,Fcgr2b,Rasgrp1,Ago3,Ccl12,Pik3r5,Nck1,Angpt1,Myd88,Tnfsf10,Met,Gpr35,Kitl,P2ry12,Jun,Mdfic,Il1a,Ccl3,Cx3cl1,Tnf,Mapkbp1,Syk,Sik3,Ccl4,Kdr,Axl,Pmaip1,Trim13,Il1b,Pik3r6,Dhx58,Ccl22,Mlkl,Sirt1,Pdgfc,Osm,Cav1,Lyn,Prkce,Tnfsf14,Tlr3,Ikbkg,Htr2b,F10,Adora2b,Bmp2,Thbs1,Rapgef2,Plscr1,Ksr1,Cflar,Mid1,Il6,Atm |
| 1.695e-26 | -59.34 | GSE17721_12H_VS_24H_LPS_BMDC_UP | MSigDB lists | GSE17721_12H_VS_24H_LPS_BMDC_UP | 192 | 67 | 15632 | 1249 |
Med21,Plek,Slc7a8,Car13,Oas2,Parp12,Adora2b,Gpr85,Fndc3a,Dcbld2,Ppp2r2a,Inpp1,Rgs14,Parp8,Klf6,Spryd7,Aebp2,Ccng2,Oaf,Gpr84,Tnfsf8,Rffl,Gbp9,Gbp4,Fgr,Socs1,Isg15,Psme1,Itga4,Daxx,Mdfic,Prpf38a,Myd88,Sav1,Sgk3,Ifit3,Zc3h12c,Casp4,Tor3a,Birc3,Ube2e2,Jag1,Rcn1,Irf1,Ifit3b,Tmod3,Vrk2,Rbms1,Tnfaip2,Kdr,Zyx,Spsb1,Nfkbia,Morc3,Rnf114,Itgav,Irf4,Katna1,Il6,Ccl22,Nxf1,Aldh1b1,Nr1h3,Atf3,Tlr6,Chmp4b,Slc28a2 |
| 1.790e-26 | -59.28 | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | MSigDB lists | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | 214 | 71 | 15632 | 1249 |
Arl4a,Cdk5r1,Egr1,Atf3,Gclc,Ets2,Jun,Tiparp,Fos,Sod2,Dhrs9,Bcl2a1b,Ccl12,Spsb1,Nfkbia,Gadd45b,Il6,Dusp2,Spry2,Kcnj2,Ier3,Trib1,Egr3,Armc8,Cdkn1a,Trem1,H3f3b,Ccl4,Rgs1,Cflar,Sik3,Birc3,Zfp36,Il1a,Atp11a,Icam1,Ier2,Tnfaip3,Cd14,Cd83,Tcf4,Tnf,Klf6,Ehd1,Dusp1,Bcl2a1d,Rhoq,Egr2,Rab11fip1,Cxcl10,Ptgs2,Zc3h12a,Larp1,Ptger4,Il1b,Pkp4,Serpinb2,Il1rn,Cxcl1,Bcl2a1a,Fosb,Plk2,Ppp1r15a,Klf2,Pde4b,Junb,Maff,Hk2,Cxcl2,Phlda1,Btg2 |
| 1.878e-26 | -59.24 | negative regulation of immune system process | biological process | GO:0002683 | 469 | 102 | 20694 | 1406 |
Trim30a,Lyn,Tnfrsf14,Il4ra,Casp3,Acod1,Dhx58,Tap1,Cd274,Lgals9,Axl,Plcl2,Abr,Dusp1,Atm,Cd80,Cd86,Samhd1,Prnp,Thbs1,Spn,Serpinb9,Rabgef1,Ifnb1,Il12b,Parp3,Cst7,Cd74,Samsn1,Bcl6,Tnf,Cx3cl1,Kitl,Nlrc5,Ubash3b,H2-Aa,Ccl12,Fcgr2b,Sdc4,Ccr1,Angpt1,Milr1,Pilrb1,Tmem176a,Prdm1,Gpr18,Cd200,Adar,Hmox1,Tnfaip3,Trib1,Tarm1,Tlr6,Notch1,Zc3h12a,Il18,Fgl2,Cd300lf,Lrch1,Mul1,Hlx,Htra1,Arg2,Tmem178,Nmi,Ldlr,Tapbpl,Ptprj,Peli1,H2-Ab1,Gpr68,Smpdl3b,Nfkbil1,Tap2,Fas,Tmem176b,Nfkbid,Nod2,Stap1,Clec2d,Nr1h3,Ptpn2,Irf4,Zfp36,Irak3,Pde5a,Myc,Socs1,Slfn1,Adora2a,Stat5a,Ptger4,Trafd1,Tnfsf4,Parp14,Ezr,Il10,Irf1,Slamf8,Pf4,Nfkbia,Tlr9 |
| 1.909e-26 | -59.22 | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_DN | MSigDB lists | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_DN | 187 | 66 | 15632 | 1249 |
Mmp9,Socs3,Itga5,Ier3,Tnip1,Ccl4,Cdkn1a,Tnfrsf1b,Procr,Zfp36,Oas1a,Il18rap,Nfkbiz,Egr1,Gmppb,Arrdc4,Pim3,Aff1,Tle3,Gadd45b,Nfkbia,Sqstm1,Tspan3,Znfx1,Ets2,Ccl2,Dusp2,Cnot4,Cox17,Rnf19b,Oas1g,Ptgs2,Pim1,Cxcl10,Slfn3,Il1rn,Nfkb2,Ralgds,Serpinb2,Plaur,Il1b,Glrx,Jarid2,Slfn4,Serpine1,Fubp1,Csf3,Mmp13,Cxcl2,Calcrl,Il1a,Traf1,Tnfrsf8,Ifit1,Clcn5,Relb,Ehd1,Stat5a,Lipe,Tnf,Dusp1,Traf2,Sat1,Pde1b,Ccnd1,Stk40 |
| 1.925e-26 | -59.21 | response to interferon-gamma | biological process | GO:0034341 | 124 | 50 | 20694 | 1406 |
Ccl5,H2-Q7,Stxbp3,Trim21,Gbp8,Tgtp1,Ccl9,Il12b,Mefv,Ifitm1,Ccl8,Cx3cl1,Ccl7,Ccl3,Shfl,Stxbp1,Gbp7,Ccl4,Gbp9,H2-Aa,Ccl12,Gch1,Zyx,Irgm1,Rab20,Cdc42ep4,Ccl2,Irf1,Gbp2,Evl,Tlr2,Il12rb1,Jak2,Acod1,Stat1,Flnb,Irf8,Ccl22,Nos2,Gbp4,Ciita,Irgm2,Gbp2b,H2-Eb1,Gbp3,Nmi,Stx11,Casp1,H2-Ab1,Cdc42ep2 |
| 2.121e-26 | -59.12 | GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_DN | MSigDB lists | GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_DN | 182 | 65 | 15632 | 1249 |
Irf1,Trib1,Ier3,Tlr2,Ifit3b,Ell2,Oasl1,Cdkn1a,Rbms1,Ccl4,Rgs1,Adam19,Tnfaip2,Gna15,Tnfsf14,Irf8,Ifit3,Gem,Nfkb1,Tnfrsf1b,Prpf4,Hmga1,Ezr,Hivep2,Slc7a11,Nqo1,Gclm,Dusp2,Ak4,Tgfbi,Pim1,Ptger4,Rnf19b,Hmox1,Dusp5,Il1b,Snn,Nfkb2,Serpinb2,Thbs1,Ppp1r15a,Lcp2,Serpine1,Slc7a8,Ccr1,Map4k4,Oas2,Vasp,Btg2,Pdgfb,Upp1,Icam1,Traf1,Hlx,Batf,Timp1,Tnf,Klf6,Ifit2,Txnrd1,Phldb1,Dock10,Ifi44,Pnp2,Tnfsf8 |
| 2.322e-26 | -59.02 | GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_UP | MSigDB lists | GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_UP | 177 | 64 | 15632 | 1249 |
Ak4,Tapbpl,Cdc42ep4,Arid5b,Rnf19b,Tlr3,Larp1,Parp3,Il15ra,Trafd1,Acsl5,Cxcl1,Tap2,Ascc3,Nampt,Wars,Maff,Ube2l6,Nmi,Icam1,Cd74,Socs1,Psmb10,Psme1,Cd38,Gbp2,Psmb9,Cd40,Plekhf2,Casp1,Psma6,Stat3,Slc15a3,Irf1,Slc25a22,Fam111a,Mthfd2,Dram1,Max,Casp7,Ifi35,Dyrk2,C3,Rbms1,Jak2,Itgal,Irf8,Casp8,Lap3,Psmb8,Tnfrsf1b,Met,Isg20,Zfp36,Psme2,Rtp4,Rars,Atf3,Tap1,Dock4,Rnf114,Sod2,Optn,Ctsc |
| 2.357e-26 | -59.01 | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 799 | 155 | 15632 | 1249 |
Tab2,Cd74,Pdgfc,Ccl3,Plagl2,Myd88,Traf5,Traf2,Ankrd17,Tnf,Glipr2,Dhx58,Stat3,Adora2b,Il18,Map3k8,Tlr3,Crkl,Ripk2,Hmox1,Il1b,Htr2b,Irak2,Ikbke,Gcnt2,Kitl,Fzd5,Osm,Pdgfrb,Map2k1,Ccr1,Dusp6,Ccl5,Gja1,Rapgef2,Mul1,Cx3cl1,Ddx60,Nck1,Fas,Nek6,Spred1,Zc3hav1,F10,Il15,Ptpn2,Eif2ak2,Gadd45b,Syk,S1pr2,Pde5a,Mid1,Gadd45g,Lpar1,Lyn,Ptk2,Tlr9,Mtdh,Sema4c,Pim2,C3,Ptgir,Notch2,Jak2,Ccl4,Rel,Cav1,Casp8,S100a8,Atm,Ikbkg,Tnfrsf1b,Rictor,Csf1,Slc9a1,Icam1,Il1a,Fgr,Trim12c,Sphk1,Malt1,Lif,Daxx,Notch1,Ripk3,Mdfic,Rhoc,Crlf3,Nod1,Bmp2,Hspa1a,Birc2,Cd40,Src,Axl,Casp1,Dbnl,Ptgs2,Il12b,Cxcl10,Fpr1,Ptger4,Ptprj,Traf3ip2,Dusp5,Zc3h12a,Pf4,Tnfsf10,Thbs1,Plk2,Pik3r6,Txn1,Csf3,Hap1,Pdgfb,Wdr59,Tnfsf15,Ccl22,Trim13,Tlr6,Mapkapk2,Tnfrsf14,Angpt1,Htr2a,Jun,Flt1,Map3k6,Ccl12,Pik3r5,Bcl2l11,Nod2,Edn1,Spry2,Prkce,Ccl2,Il6,Peli1,Tlr2,Adrb2,Nox1,Socs3,Cflar,Clcf1,Hcls1,Kdr,Il10,Tnfsf14,Birc3,Clec4n,Rnf31,Sirt1,Rasgrp1,Eef1e1,Ksr1,Cysltr2 |
| 2.502e-26 | -58.95 | GSE2706_2H_VS_8H_R848_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_R848_STIM_DC_DN | 172 | 63 | 15632 | 1249 |
Gpr18,Dock4,Eif2ak2,Slc7a11,Bcl2l11,Samd9l,Dusp4,Parp9,Pla2g4a,Parp14,Fpr2,Xrn1,Ifi214,Ddx60,Usp25,Ifi207,Pnpt1,Sema3c,Mndal,Plod2,Lap3,Psat1,Tdrd7,Ifi203,Xaf1,Ifi211,Tnip3,Ifi204,Ifi35,Tnfsf4,Casp7,Stat1,Jak2,Ifi205,Ifi209,Ifi213,Ifi44,Itgb8,Ddx58,Stat2,Trim12c,Dtx3l,Apaf1,Etv5,Asns,Cd86,Txn1,Brwd3,Wars,Oas2,Ube2l6,Rab10,Tnfsf15,Nmi,Ifi208,4930453N24Rik,Slc31a1,Epsti1,Sp110,Cmpk2,Trafd1,Tnfsf10,Thbs1 |
| 2.527e-26 | -58.94 | positive regulation of cell death | biological process | GO:0010942 | 694 | 129 | 20694 | 1406 |
Gadd45b,Il12b,Agrn,Bcl6,Bnip3,Malt1,Nqo1,Ifnb1,Nod1,Notch2,Rgcc,Egr1,Ccl5,Cd40,Nox1,Casp8,Pml,Atf3,Cdkn1a,Fcgr2b,Ccl12,Pla2g4a,Ift57,Nck1,Tnfsf10,Nsmaf,Sod2,Jun,Fam162a,Ccl3,Daxx,Tnf,Syk,Dusp6,Pmaip1,Trim13,Hp,Txnrd1,Cd274,Il1b,Sirt1,Mmp9,Osm,4930453N24Rik,Cav1,Lyn,Cdk5r1,Nr4a3,Casp3,Itpr1,Casp2,Bmp2,Ctsc,Fam72a,Rapgef2,Thbs1,Pik3cd,Plscr1,Prnp,Fos,Ifit2,Tnfrsf8,Ptgs2,Il6,Atm,Dusp1,Hif1a,Kmo,Sav1,Gadd45g,Itga4,Pde5a,Myc,Ptpn2,Pdgfrb,Plagl2,Nfkbid,Col18a1,Hcar2,Fas,Nupr1,Dnaja1,Sp110,Il10,S100a8,Map2k4,Plaur,Nr4a1,Ddit4,Adrb2,Apaf1,Hdac1,Slc9a1,Irf1,Tspo,Eif2ak2,Adora2a,Eef1e1,Dcun1d3,Ppp2r1b,Plekhn1,Nlrp3,Notch1,Optn,Il18,Tnfrsf1b,Zc3h12a,Cycs,Inhba,Cysltr2,Hmox1,Ripk3,Uaca,Nlrc4,Jak2,Tlr6,Stat1,Casp1,Nr3c1,Casp4,Src,Phlda1,Bcl2l11,Tnfsf15,Ripk2,Mul1,Lpar1,Klrk1,Traf2 |
| 2.751e-26 | -58.86 | GSE9960_HEALTHY_VS_GRAM_POS_SEPSIS_PBMC_DN | MSigDB lists | GSE9960_HEALTHY_VS_GRAM_POS_SEPSIS_PBMC_DN | 162 | 61 | 15632 | 1249 |
Nlrc5,Sod2,Kcnj2,Mmp14,Ifrd1,Samd9l,Ddx60,Palld,Lrp8,Etv3,Pttg1,Plagl1,Il4ra,Slc25a25,Slamf7,Cd80,Pnpt1,Ahr,Birc3,Pstpip2,Isg20,Trim14,Jag1,Rasgrp1,Ebi3,Stat1,Whamm,Ppfibp2,Nfil3,Ifit2,Apobec3,Oas3,Ifi44,Rsad2,Mcoln2,Stat2,Traf1,Ifih1,Isg15,Tnfaip3,Txn1,Brd2,Gch1,Ccl5,Cd274,Ppm1k,Irf7,Nrp2,Slc2a6,Inhba,AA467197,Oas2,Ptger4,Herc6,Pcgf5,Dusp5,Ak4,Acsl5,Nfkb2,Sp110,Trafd1 |
| 2.800e-26 | -58.84 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | 157 | 60 | 15632 | 1249 |
Rasgrp1,Ifi203,Tmem176a,Ifi211,Mndal,Trem1,Dnajb2,Acvr1b,Ifi204,Acsl1,Tlr2,Etnk1,Socs3,Stat1,Cd200,Vcan,Nqo1,Cpd,Jun,Bcl2a1b,Dhrs9,Slc7a11,Ifi207,Olr1,Arl4a,Ifi214,Papss2,Tmem176b,Oas2,Ext1,Ifi208,Phlda1,Plk2,Klf2,Gdf15,Dusp6,5430427O19Rik,Il1rn,Bcl2a1a,Plat,Trib3,Slamf8,Clec5a,Uchl1,Rbpms,Bcl2a1d,Rhoq,Ifi44,Slc15a3,Ifi209,Ifi205,Klf6,Ifi213,Irak3,Gbp2,Upp1,Cd180,Fabp3,Ch25h,Nupr1 |
| 3.042e-26 | -58.75 | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_UP | MSigDB lists | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_UP | 183 | 65 | 15632 | 1249 |
Edn1,Prkce,Phlpp1,Rin2,Gadd45g,Ezr,Ccl12,Bcl2l11,Fos,Rbms2,Fbxo4,Chmp4b,Etv3,Plagl1,Isg20,Plscr1,Ccrl2,Kctd12,Rhou,Rabgef1,Clec4n,Ednrb,Rel,Il10,Ogfr,Gem,Arf4,Ccl4,Frmd6,Nfil3,Socs3,Oasl1,Trib1,Tbc1d1,Dhx58,N4bp1,Arid5a,Tpst1,Sav1,Cd14,Daxx,Pdgfc,Clcn5,Rhoh,Lif,Pml,Ext1,Sap30,Trim26,Phlda1,H2-Aa,Cxcl2,Tor1aip1,Cxcl1,Plcl2,Plat,Serpinb2,Gcnt2,Plaur,Trafd1,Cmpk2,Rnf19b,Traf3ip2,Adora2b,Rcan1 |
| 4.350e-26 | -58.40 | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_DN | 184 | 65 | 15632 | 1249 |
Serpinb9,Traf3ip2,Ripk2,Il15ra,Pkp4,Vegfc,Htr2b,Sp110,Slfn3,Slfn4,Asns,Serpine1,Hsd17b12,Tbc1d13,Oas2,Maff,Hk2,Rilpl1,Reps1,Fabp3,Myd88,Timp1,Slc2a1,Ifit2,Stat5a,Ifnar1,Ddhd1,Lztfl1,Gsr,Stk40,Dhx58,Lyn,Ebi3,Mtdh,Mtmr14,Ell2,Dusp16,Lhx2,Esd,Cdkn1a,Fscn1,Znrf1,Casp4,Nfkb1,Ccrl2,Tdrd7,Srxn1,St3gal5,Usp25,Ahr,Slc28a2,Hinfp,Zbp1,Cited2,Tiparp,Adhfe1,Map3k6,Nfkbia,Ccl12,Sqstm1,Vcan,Cpd,Parp14,Prokr1,Ccl2 |
| 4.415e-26 | -58.38 | regulation of cell migration | biological process | GO:0030334 | 886 | 150 | 20694 | 1406 |
D1Ertd622e,Dach1,Cx3cr1,Tnfsf4,Acvr1,Evl,Slamf8,Ccl2,Plau,Glipr2,Stat5a,Pdpn,Vegfc,Ptger4,Mecp2,Plpp3,Bst1,Cmklr1,Ptk2,Mmp14,Rhoc,Prkx,Svbp,Myc,Itga4,Pdgfrb,Nod2,Pla2g7,Flrt2,Serpine1,Tmsb10,Carmil1,Col18a1,Spry2,Fas,Dock4,Csf1,Sema4c,Stap1,Edn1,Fpr2,Map2k1,Dock10,Ptprj,Mtus1,Sema3c,Map4k4,Gcnt2,Stat3,Src,Lrch1,Lpar1,Spred1,Pdgfb,Ptafr,Cxcl10,Flt1,Sele,Akt3,Notch1,Il18,Zc3h12a,Swap70,Trib1,Ripk3,Hmox1,Tlr2,Rnd3,Ddx58,Cd200,Gpr18,Crkl,Sphk1,Timp1,Jak2,Ccr1,Spata13,Sdc4,Abcc1,Rras2,Ccl12,Nck1,Myd88,Angpt1,Met,Acvrl1,Kitl,Jun,P2ry12,Sod2,Rffl,P2ry2,Il1a,Cx3cl1,Cited2,Ccl4,Kdr,Cd74,Rnd1,Il1rn,Irs2,Icam1,Rgcc,Sinhcaf,Ccl5,Egr1,Rabgef1,Igf1r,Cd40,Fgr,Clic4,Cxcl14,Sema4a,Adora2b,Rap2c,Bmp2,Spn,Thbs1,Pik3cd,Rapgef2,Plk2,Abr,Syne2,Jag1,Ptgs2,Cnn2,Atm,Hif1a,Acvr1b,Itga5,Dusp1,Fubp1,Lgals9,Cd274,Il1b,Mdm2,Mmp9,Sirt1,Pdgfc,Tnfrsf14,Cav1,Sell,Lyn,Nr4a3,Prkce,Tnfsf14,Myadm,Rhof,Itgav,Lmo4 |
| 4.765e-26 | -58.31 | GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 1474 | 233 | 15632 | 1249 |
Pik3r5,Ccl12,Cenpe,Jun,Myc,Il6,Ppp2r5a,Ccl2,Spry2,Lrp8,Tlr6,Mapkapk2,Prnp,Ccl22,Phip,Ifna1,Prdx1,Mark2,Pdk3,Socs3,Acsl1,Acvr1b,Aida,Kdr,Hcls1,Fam20c,Prkar2b,Igf1r,Lrp4,Ifnar1,Ppp6r1,Dusp1,Swap70,Dbnl,Acvrl1,Acvr1,Pml,Hhex,Sphk1,Fgr,Icam1,Bmp2,Nod1,Ripk3,Daxx,Map4k4,Txn1,Pik3r6,Tnfsf15,Uchl1,Dusp5,Ptprj,Il12b,Pim1,Plcl2,Sqstm1,Syk,Spn,Eif2ak2,Dnaja1,Stap1,Ifnb1,Dusp4,Pde5a,Phlpp1,Nck1,Irs2,Tpx2,Mul1,Il15,Ikbkg,Ppp1r15b,Atm,Csf1,Mmd,Itga5,Sema4c,Ptk2,Lyn,Trib1,Rap2c,Ccl4,Ldlr,Jak2,Pmepa1,Cdkn1a,Vrk2,Dusp16,Tnf,P2ry13,Traf2,Hspa2,Errfi1,Cd74,Tnfaip3,Rgs3,Gdf15,Ccl5,Myadm,Dusp6,Plek,Ppp1r15a,Lcp2,Flrt2,Fzd1,Inhba,Rapgef2,Tlr3,Crkl,Trib3,Irak2,Pilrb1,Ppp2r2a,Flrt3,Nlrc5,Ezr,Map3k6,Flt1,Psmd10,Prkce,Edn1,Nod2,Atf3,Ccnd2,Adar,Htr2a,Angpt1,Tnfrsf14,Atp2b4,Ccne1,Rabgef1,Cysltr2,Ksr1,Rasgrp1,Sirt1,Nox1,Adrb2,Tnip1,Clcf1,Socs7,Src,Hsph1,Cd40,Rgs14,Cish,Dusp8,Casp3,Stk40,Ccnd1,Lif,Rhoh,Malt1,Trim12c,Socs1,Calcrl,Hif1a,Il1a,Smg7,Mdfic,Samsn1,Ifna6,Pdgfb,Adora2a,Csf3,Zc3h12a,Ptger4,Fpr1,Ptafr,Cxcl10,Thbs1,Pf4,Plaur,Vegfc,Ppp1r14b,Gadd45b,Ptpn2,Dusp2,Gadd45g,Mid1,Ifna5,S1pr2,Cdkn2d,Fas,Cx3cl1,Cdk5r1,Kat2b,Ubash3b,Cd80,Tspo,Pilrb2,Sdc4,Me1,Rbl1,Dusp14,Spred1,Tnfrsf1b,Ednrb,Lmo4,Nos2,Cav1,Pid1,Rictor,Mmp9,Ptgir,C3,Tlr9,Lpar1,Ppp2r1b,Stat3,Rbpms,Glipr2,Fabp3,Tab2,Irak3,Ifna2,Mvp,Ccl3,Pdgfc,Ccr1,Map2k1,Pdgfrb,Osm,Fzd5,Ddit4,Ppp2r3a,Ripk2,Map3k8,Il18,Adora2b,Gcnt2,Kitl,Htr2b,Il1b |
| 4.893e-26 | -58.28 | regulation of kinase activity | biological process | GO:0043549 | 787 | 139 | 20694 | 1406 |
Tnf,Mapkbp1,Daxx,Mdfic,Kitl,Dusp6,Nlrc5,Tpx2,Ubash3b,Syk,Ccnj,Rasgrp1,Sdc4,Cdkn1a,Met,Angpt1,Nck1,Pik3r5,Egr1,Rgcc,Uchl1,Cdkn2d,Kat2b,Irs2,Wars,Map3k6,Fgr,Rbl1,Cd40,Igf1r,Il1rn,Agrn,Il12b,Tlr1,Spred3,Gadd45b,Cd74,Actb,Malt1,Dusp4,Gdf15,Aida,Dusp8,Mmd,Ksr1,Ccnd2,Higd1a,Dusp1,Acsl1,Il6,Bmp2,Rap2c,Dusp2,Prnp,Dusp5,Hsph1,Rapgef2,Fam72a,Thbs1,Ccnd1,Cdk5r1,Psmd10,Lyn,Cav1,Ppp2r5a,Casp3,Lmo4,Htr2b,Ikbkg,Il1b,Pik3r6,Hhex,Lgals9,Trib3,Pdgfc,Sirt1,Mlkl,Socs1,Eif2ak2,Adora2a,Map3k8,Cenpe,Atp2b4,Map2k4,Slamf8,Fcgr1,Adrb2,Tlr9,Lrp8,Csf1,Spry2,Ccng2,Mtcp1,Nod2,Edn1,Stap1,Dusp16,Dnaja1,Prkar2b,Ptk2,Fzd5,Ptpn2,Pdgfrb,Irak3,Pde5a,Htr2a,Gadd45g,Tab2,Mvp,Ripk2,Mul1,Lpar1,Tnfsf15,Irgm2,Flt1,Traf2,Nek6,Pdgfb,Spred1,Ptprj,Map2k1,Fpr2,Ccne1,Src,Map4k4,Pim1,Adar,Ripk3,Tnfaip3,Trib1,Jak2,Tlr6,Errfi1,Crkl,Rhoh,Ranbp2,Rgs14,Il18,Irak2 |
| 5.892e-26 | -58.09 | GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM | MSigDB lists | GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM | 418 | 103 | 15632 | 1249 |
Gbp2b,Ifit3b,Ifi204,Oasl1,Tlr9,Trim56,Slpi,Isg20,Ifi211,Nos2,Mndal,S100a8,Zc3hav1,Ifi207,Clec4e,Ifi214,Ddx60,Ifna5,Ifnb1,Optn,Bnip3,Nlrc4,Syk,Spn,Plac8,Eif2ak2,Ripk2,Hp,Tlr3,Ddit4,Serpine1,Irf7,Fcgr4,Ifna2,Myd88,Batf,Ifih1,Dhx58,Rsad2,Gbp9,Tnfsf8,Batf2,Ifi209,Ankrd17,Oas3,H2-Q6,Tnf,Ifit2,Trem1,Tlr2,Fam111a,Irf1,Stat1,Itpkc,Tnfsf4,Ifi203,Leng9,Oas1a,Plscr1,Irf8,Il10,Ifit3,Clec4n,Samhd1,Tnfrsf14,Adar,Ifna1,Il4ra,Nlrp3,Tlr6,Nod2,Il6,Irf4,H2-Q4,Nlrc5,Ifit1bl1,Elmod2,Il12b,Cxcl10,Clec4d,Oas1g,Zc3h12a,Oas2,Ifi208,Ifna6,Tlr1,Cd86,Ifit1bl2,Ifit1,Nod1,Isg15,Fgr,Trim12c,Stat2,Ddx58,Pml,H2-Q7,Gbp4,Cd40,Ifi205,Apobec3,Ifnar1,Ifi213 |
| 6.201e-26 | -58.04 | GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_DN | MSigDB lists | GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_DN | 185 | 65 | 15632 | 1249 |
Gpr18,Tet2,Jun,D16Ertd472e,Gadd45b,Agrn,Optn,Mllt6,Irgm2,Il6,Bbx,Peli1,Phip,Etv3,Pikfyve,Nfkbiz,Rras2,Rnd3,Pde3b,Il10,Lap3,Heatr6,Birc3,Nfkb1,Lnpep,Rictor,Ksr1,Ms4a6d,Ebi3,Socs3,Pim2,Cd200,Dusp16,Nfil3,Fscn1,Rbms1,Clcf1,Cflar,Arid5a,Swap70,Aebp2,Fut8,Ubtd2,Gbp9,Gbp4,Zfp281,Sell,Gbp3,Hck,Gbp2,Tnfaip3,Mapkbp1,Batf,Ppm1k,Osm,4930523C07Rik,Card6,Sh3bp4,Car13,Hk2,Icosl,Tlr1,Cxcl10,Il12b,Pcgf5 |
| 7.341e-26 | -57.87 | TNF signaling pathway | KEGG pathways | ko04668 | 107 | 51 | 7931 | 713 |
Traf1,Birc2,Ptgs2,Traf5,Cxcl2,Cxcl3,Akt3,Cx3cl1,Nfkb1,Jun,Il6,Icam1,Junb,Il15,Csf1,Ccl12,Socs3,Map2k1,Ccl5,Lif,Ccl2,Cflar,Tnfaip3,Gm5431,Fos,Edn1,Birc3,Casp7,Tnfrsf1b,Mmp9,Nfkbia,Mmp14,Fas,Tnf,Cxcl10,Traf2,Casp8,Pik3cd,Sele,Map3k8,Cxcl1,Ikbkg,Vcam1,Ripk3,Il1b,Tab2,Ifi47,Nod2,Casp3,Map2k4,Mlkl |
| 7.341e-26 | -57.87 | TNF signaling pathway | KEGG pathways | mmu04668 | 107 | 51 | 7931 | 713 |
Traf5,Cxcl2,Traf1,Birc2,Ptgs2,Cx3cl1,Nfkb1,Jun,Cxcl3,Akt3,Csf1,Ccl12,Socs3,Map2k1,Il6,Icam1,Junb,Il15,Edn1,Birc3,Casp7,Tnfrsf1b,Ccl5,Lif,Tnfaip3,Cflar,Ccl2,Gm5431,Fos,Traf2,Casp8,Pik3cd,Mmp9,Nfkbia,Mmp14,Fas,Cxcl10,Tnf,Sele,Map3k8,Cxcl1,Ifi47,Nod2,Ikbkg,Ripk3,Vcam1,Il1b,Tab2,Mlkl,Casp3,Map2k4 |
| 8.815e-26 | -57.69 | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP | 186 | 65 | 15632 | 1249 |
Arf4,Kdr,Rgs1,Tagap,Pmepa1,Ebi3,Ifi35,Socs3,Asb13,Slc25a22,Plscr1,Nfkbib,Eef1e1,Xaf1,Tnfsf14,Irf8,Adar,Tap1,Atf3,Cdk5r1,Rtp4,Irgm2,Parp14,Edn1,Slfn8,Il6,Nfkbia,Agrn,Cited2,Il1rn,Slfn9,Sec24a,Il15ra,Ptges,Larp1,Fndc3a,Zc3h12a,Pcgf5,Serpinb9,Cxcl10,Hk2,Nampt,Ccl5,Ppp1r15a,Lgals9,Ascc3,Batf,Ifit1,Notch1,Pml,Csrnp1,Usp18,Icam1,Dtx3l,Isg15,Socs1,Top3a,Ly75,Ifi44,Gbp4,Gbp9,Aebp2,Mdm2,Mafk,Dock10 |
| 9.173e-26 | -57.65 | GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE | 497 | 114 | 15632 | 1249 |
Tlr6,Mapkapk2,Nlrp3,Il4ra,Fcgr1,Tnfrsf14,Nfkbia,Nlrc5,H2-Q4,Cyfip1,Psmd10,Prkce,Il6,Nod2,Tnfsf4,Tlr2,Pik3cd,Tnip1,Clcf1,Actb,Rnf31,Psmb8,Birc3,Clec4n,C1rl,Marco,Plscr1,Ifi203,Rasgrp1,Sirt1,Psme1,H2-Q7,Malt1,Hlx,Fgr,Trim12c,Ddx58,Cd180,Nod1,Myo10,Hck,Relb,Ifi213,Src,Tank,Ifi205,Birc2,Cd40,Psmb9,Dennd1b,C1ra,Psma6,H2-Ab1,Cd55,Ptprj,Il12b,Clec4d,Ptafr,Cd86,Tlr1,Ifi208,Nck1,Ifi214,Clec4e,Cd80,Il15,Ifi207,Syk,Nlrc4,Ifnb1,C3,Ptk2,Tlr9,Lyn,Tnip3,Cacnb3,Ifi204,Ikbkg,Nfkb1,Casp8,Mndal,Psme2,Ifi211,Aim2,Psmb10,Ifih1,Tab2,Cd74,Cd14,Myd88,Tnfaip3,Irak3,Cd38,Tnf,Ifi209,H2-Q6,Traf2,Rsad2,Ripk2,Psmb6,Tlr3,Nr4a3,Adora2b,Irak2,Ikbke,Il1b,Ccl5,Pde4b,H2-Eb1,Irf7,Lcp2,Fzd5,H2-Aa,Il12rb1 |
| 9.807e-26 | -57.58 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 1257 | 208 | 15632 | 1249 |
Nmi,Ifi208,Nfkbid,G3bp2,Txn1,Ifit1bl2,Tnfsf10,Plcl2,Il1rn,Uchl1,Dusp5,Scyl2,Cd55,Ptprj,Il12b,Rffl,Acvr1,Lrp4,Ifi213,Dusp1,Ifi205,Psmb9,Bmp2,Psme1,H2-Q7,Nfkbil1,Hhex,Icam1,Smpdl3b,Il10,Igf1r,Socs3,Tnfsf4,Sema4a,Aida,Myc,Spry2,Il18bp,Ccl12,Nfkbia,Cx3cr1,H2-Q4,Gclc,Pde3b,Plau,Il4ra,Phip,Prnp,Fzd1,Vasn,Sh3bp4,Dusp6,Myadm,Ccl5,Plek,Flrt2,Ppp1r15a,Tlr3,Dhx58,Errfi1,Hdac1,Tnf,Bcl6,H2-Q6,Traf2,Cd14,Tnfaip3,Rgs3,Cd74,Tulp3,Med13,Nfkbib,Psme2,Fabp7,Ppp1r15b,Nfkb1,Atm,Casp8,Mndal,Sema3c,Rpgrip1l,Pmepa1,Dusp16,Sema4c,Lyn,Trib1,Stap1,Phactr4,Ifnb1,Dusp4,Phlpp1,Sod2,Eif2ak2,Spn,Dnaja1,Ifi207,Nck1,Mul1,Ifi214,Pdgfb,Samsn1,Serpinb2,Thbs1,Bambi,Trafd1,Pf4,Plaur,Zc3h12a,Ptger4,Serpinb9,Grina,Cish,Dusp8,Psma6,Ccnd1,Mdm2,Hsph1,Src,Hspa1a,Itpr1,Rgs14,Bfar,Notch1,Rhoh,Lif,Hlx,Socs1,Il1a,Hif1a,Calcrl,Htra1,Ifi203,Met,Sirt1,Rabgef1,Psmb8,Ptch1,Rgs1,Tnip1,Cflar,Socs7,Stat1,Adrb2,Mefv,Edn1,Irf4,Chst11,Ncoa5,Flrt3,Nlrc5,Ifit1bl1,Ezr,Psmd10,Adar,Tap1,Angpt1,Atp2b4,Chmp4b,Egr1,Abr,Atf3,Nlrp3,Ddit4,Ppp2r3a,Gja1,Serpine1,Plat,Il1b,Htr2b,Hmox1,Psmb6,Hp,Nr4a3,Ifi209,Rnf34,Irak3,Tsku,Prdm1,Psmb10,Ifi211,Tnfrsf1b,Pid1,Cav1,Mmp9,Ptgir,Tlr9,Tnip3,Ifi204,Mmp14,Dusp2,Gclm,S1pr2,Optn,Itgav,Ptpn2,Tspo,Gpc1,Cd34,Pim3,Dusp14,Spred1,Cdkn2d,Usp25,Fas,Znrf3,Nr1h3,Cx3cl1,Ubash3b |
| 1.097e-25 | -57.47 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | 176 | 63 | 15632 | 1249 |
Ak4,Rcan1,Nr4a3,Ptger4,Rnf19b,Rtn1,Dusp5,Glrx,Acp2,Vcam1,Il1rn,Ppp1r15a,Txn1,Ifit1bl2,Dusp6,Gch1,Wars,Rapgef2,Oas2,Stx11,Ube2l6,Tlr1,Icam1,Traf1,Psmb10,Gbp2,Cd83,Crlf3,Timp1,Ifit2,Dusp1,Cst7,Acvrl1,Sat1,Ifi44,Ier3,Gpd2,Endod1,Ell2,Mmp9,Vrk2,Tnfaip2,Adam19,Rgs1,Ldlr,Ccl4,S100a8,Nfkb1,Trim21,Plscr1,Psme2,Kat2b,Arl4a,Lrp8,Olr1,Dnaja1,Nfkbia,Gadd45b,Ifit1bl1,Ccl12,Agrn,Vcan,Pdpn |
| 1.141e-25 | -57.43 | Herpes simplex infection | KEGG pathways | ko05168 | 212 | 73 | 7931 | 713 |
Ifna2,Tlr9,Ddx58,Ifna1,Cd74,Tlr2,Oas1g,Taf4b,Ifih1,Tap1,Tlr3,Traf2,Ikbke,H2-Q6,Casp8,Ifit1,Tnf,Daxx,Nfkbia,Fas,Irf7,Tnfsf14,Ifnb1,H2-Q4,Casp3,Cycs,Eif2ak2,Ifna6,Il1b,Il12b,C3,Tab2,H2-Ab1,Ikbkg,Jak2,Myd88,Oas1a,Nfkb1,Sp100,Jun,Tyk2,Pilra,Stat1,Pml,H2-Aa,Traf5,H2-M2,Ifnar1,Nfkbib,Oas3,Oas2,H2-T10,Ifit1bl1,Traf1,Ifna5,Oas1b,Nectin2,Ccl2,Tnfrsf14,Nxf1,Fos,Ccl5,Tap2,H2-T22,Socs3,Ccl12,H2-T24,H2-Q7,H2-Eb1,Il15,Ifna4,Stat2,Il6 |
| 1.141e-25 | -57.43 | Herpes simplex infection | KEGG pathways | mmu05168 | 212 | 73 | 7931 | 713 |
Nfkbia,Daxx,Irf7,Fas,Tnf,Traf2,Ikbke,Ifit1,H2-Q6,Casp8,Tlr3,Ifih1,Taf4b,Tap1,Oas1g,Cd74,Ifna1,Ddx58,Tlr2,Tlr9,Ifna2,Myd88,H2-Ab1,Ikbkg,Jak2,Oas1a,Il12b,Il1b,C3,Tab2,Ifna6,Eif2ak2,Casp3,Cycs,H2-Q4,Tnfsf14,Ifnb1,Ifna5,Traf1,Ifit1bl1,Ifnar1,Nfkbib,H2-T10,Oas2,Oas3,Traf5,H2-M2,Pml,H2-Aa,Stat1,Nfkb1,Sp100,Jun,Tyk2,Pilra,Ifna4,Il6,Stat2,H2-Eb1,Il15,H2-Q7,Socs3,Ccl12,H2-T24,Ccl5,H2-T22,Tap2,Nxf1,Tnfrsf14,Ccl2,Fos,Nectin2,Oas1b |
| 1.160e-25 | -57.42 | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | 361 | 94 | 15632 | 1249 |
Il18,St3gal1,Slc31a1,Sp110,Il1b,Slc29a3,Serpine1,Ccr1,Dusp6,Cxcl2,Ddit4,H2-Aa,Kmo,Irak3,Myd88,Cd14,Tpst1,Plod3,Rsad2,Lpar1,Tnip3,Rab20,Mmp9,C3,Notch2,Pid1,Sik3,Rap1gap2,Alas1,Nr1h3,Slc30a1,Me1,Clec4e,Slamf7,Ets2,Aoah,Eif2ak2,Sod2,Sqstm1,Rin2,Gadd45g,Cpd,Gclm,Nat2,Slc43a3,Slamf8,Clec5a,Fpr1,Cxcl10,Cd55,Cmklr1,Plcl2,Rnaset2a,Snx10,Rgl1,Nampt,Tuba4a,Hk2,Tlr1,Il1a,Sphk1,Sell,Crim1,Itpr1,Acpp,Casp1,Ccnd1,Gsr,Tbc1d1,Rhoq,Pnp2,Gpd2,Stat1,Rnaset2b,Trem1,Itgal,Il10,Ltbp2,Pla2g7,Ccrl2,Akt3,Plscr1,Dmxl2,Nlrp3,Pgs1,Egr1,Prdx1,Tspan3,Dock4,Cx3cr1,Slc7a11,Ccl12,Sdc2,Nqo1 |
| 1.395e-25 | -57.23 | GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | 156 | 59 | 15632 | 1249 |
Aim2,Mcoln2,Il1a,Ddx58,Usp18,Plagl2,Dusp1,Gpr84,Tnc,Errfi1,Bcl2a1d,Dhx58,Ptger4,Usp42,Ptgs2,Nr4a3,Map3k8,Bcl2a1a,Bambi,Irak2,Il15ra,Snn,Zhx2,Nampt,Gch1,Ccl5,Gja1,Nrp2,Gpr132,Tnfsf15,Rapgef2,Cxcl2,Adora2a,Stx11,Zbp1,Klf7,Zc3hav1,Nlrc5,Bcl2a1b,D16Ertd472e,Trip10,Il4i1,Peli1,Il6,Samd9l,Ifnb1,Dram1,Oasl1,Irf1,Acsl1,Tnfaip2,Abtb2,Nfkb1,Zc3h12c,Gem,Stat4,Usp12,Rasgrp1,Il18rap |
| 1.424e-25 | -57.21 | regulation of cell motility | biological process | GO:2000145 | 933 | 154 | 20694 | 1406 |
Irs2,Icam1,Rgcc,Sinhcaf,Ccl5,Rabgef1,Egr1,Igf1r,Cd40,Fgr,Clic4,Cxcl14,Cd74,Rnd1,Il1rn,Kitl,Rffl,Sod2,P2ry12,Jun,P2ry2,Il1a,Cx3cl1,Cited2,Ccl4,Kdr,Ccr1,Spata13,Abcc1,Sdc4,Rras2,Ccl12,Nck1,Myd88,Angpt1,Met,Acvrl1,Sell,Cav1,Tnfrsf14,Lyn,Nr4a3,Prkce,Myadm,Tnfsf14,Rhof,Lmo4,Itgav,Fubp1,Lgals9,Cd274,Ppp2r3a,Il1b,Mdm2,Sirt1,Mmp9,Pdgfc,Abr,Syne2,Jag1,Ptgs2,Cnn2,Atm,Acvr1b,Itga5,Hif1a,Dusp1,Sema4a,Adora2b,Rap2c,Bmp2,Spn,Pik3cd,Thbs1,Plk2,Rapgef2,Pla2g7,Nod2,Flrt2,Carmil1,Serpine1,Tmsb10,Spry2,Col18a1,Dock4,Fas,Csf1,Sema4c,Edn1,Stap1,Ptk2,Mmp14,Rhoc,Prag1,Prkx,Svbp,Itga4,Myc,Pdgfrb,Glipr2,Stat5a,Pdpn,Vegfc,Ptger4,Mecp2,Plpp3,Bst1,Cmklr1,D1Ertd622e,Dach1,Cx3cr1,Tnfsf4,Acvr1,Evl,Slamf8,Plau,Ccl2,Igsf8,Trib1,Ripk3,Tlr2,Hmox1,Rnd3,Ddx58,Gpr18,Cd200,Crkl,Sphk1,Spint2,Timp1,Jak2,Sele,Akt3,Notch1,Il18,Zc3h12a,Swap70,Lpar1,Lrch1,Spred1,Pdgfb,Ptafr,Cxcl10,Flt1,Fpr2,Map2k1,Dock10,Ptprj,Mtus1,Sema3c,Map4k4,Stat3,Gcnt2,Src |
| 1.569e-25 | -57.11 | regulation of protein kinase activity | biological process | GO:0045859 | 716 | 130 | 20694 | 1406 |
Dusp2,Bmp2,Rap2c,Dusp5,Prnp,Hsph1,Rapgef2,Fam72a,Thbs1,Dusp8,Ksr1,Mmd,Dusp1,Acsl1,Ccnd2,Higd1a,Il6,Hhex,Pik3r6,Il1b,Trib3,Lgals9,Sirt1,Pdgfc,Mlkl,Psmd10,Cdk5r1,Ccnd1,Cav1,Lyn,Ikbkg,Casp3,Htr2b,Sdc4,Ccnj,Rasgrp1,Cdkn1a,Met,Angpt1,Nck1,Pik3r5,Daxx,Mdfic,Mapkbp1,Tnf,Kitl,Dusp6,Ubash3b,Syk,Tpx2,Tlr1,Spred3,Gadd45b,Il1rn,Il12b,Agrn,Cd74,Malt1,Actb,Dusp4,Gdf15,Aida,Rgcc,Egr1,Cdkn2d,Kat2b,Uchl1,Wars,Cd40,Igf1r,Map3k6,Fgr,Map2k1,Ptprj,Ccne1,Src,Map4k4,Mvp,Tab2,Tnfsf15,Irgm2,Lpar1,Ripk2,Mul1,Flt1,Traf2,Nek6,Pdgfb,Spred1,Rgs14,Il18,Irak2,Ripk3,Adar,Pim1,Trib1,Tnfaip3,Errfi1,Tlr6,Jak2,Crkl,Map2k4,Adrb2,Tlr9,Fcgr1,Adora2a,Eif2ak2,Socs1,Map3k8,Cenpe,Atp2b4,Ptk2,Ptpn2,Fzd5,Pdgfrb,Htr2a,Gadd45g,Pde5a,Irak3,Lrp8,Csf1,Mtcp1,Nod2,Spry2,Ccng2,Dusp16,Edn1,Stap1,Dnaja1,Prkar2b |
| 2.009e-25 | -56.87 | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN | 183 | 64 | 15632 | 1249 |
Ccl12,Bcl2a1b,Flt1,Trip10,Dnaja1,Pdpn,Ifrd1,Atf3,Adar,Rnd3,Pfkfb3,S100a8,Birc3,Gem,Marco,Gna15,Tnfsf14,Alas1,Plscr1,Trim21,Ccrl2,Pla2g7,Ell2,Mmp9,Oasl1,Ier3,Gpd2,Tnip1,Cflar,Fscn1,N4bp1,Ifit2,Dusp1,Pnp2,Ifi44,Stat3,Bcl2a1d,Icam1,Stat2,Cd83,Myd88,Gbp2,Crim1,Txn1,Fcgr4,Lcp2,Ppp1r15a,Nrp2,Ube2l6,Oas2,Rapgef2,Wars,Inhba,Dusp5,Ldha,Slc31a1,Rnf19b,Il2rg,Pim1,Rcan1,Ak4,Bcl2a1a,Trafd1,Plaur |
| 2.009e-25 | -56.87 | GSE17721_CTRL_VS_LPS_4H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_4H_BMDC_DN | 183 | 64 | 15632 | 1249 |
Stxbp1,Hinfp,Rras2,Rbm43,Slc28a2,Olr1,Rab32,Nr4a1,Rnf114,Sqstm1,Parp14,Irgm2,Mmp14,Slc44a1,Psd,Ebi3,Dtx2,Ell2,Ier3,Kdr,Dusp16,Frmd6,Dach1,Atm,Birc3,Nfkb1,Lmo4,Nos2,Procr,Pdss1,Rnf19a,Slamf9,Eef1e1,Ube2e1,Hif1a,Socs1,Traf5,1600014C10Rik,Stau1,Gbp2,Stat5a,Plekhf2,Gypc,Plekha5,Timp1,Tcf4,Carhsp1,Lztfl1,Dhx58,Clec5a,Il18,Serpinb9,Plcl2,Ralgds,Gca,Keap1,Nampt,Jarid2,Ccnj,Serpine1,Rilpl1,Trim26,Stxbp3,Hk2 |
| 2.009e-25 | -56.87 | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_DN | MSigDB lists | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_DN | 183 | 64 | 15632 | 1249 |
Apaf1,Cd38,Hck,Cd83,Cd14,Zfp281,Fam133b,Rnf135,Ifih1,Irf2,Sele,C1ra,Tbc1d1,Oaf,Nr3c1,Tcf4,Plod3,Phldb1,Spryd7,Sp110,Hcar2,Il1b,Pim1,Nsmaf,Tlr3,Rnf19b,Mmp13,Car13,Maff,Tbc1d13,Phlda1,Noc4l,Vps54,Slc7a8,Junb,Csrp1,Spred1,Sgcb,Adar,Ccl22,Arl4a,Tpx2,Kremen1,Parp9,Ppp2r5a,Dnaja1,Hivep2,Klf3,Ccl12,Trem1,Nfil3,Znrf1,Tax1bp1,Rcn1,Ifi35,Procr,Csf1,Ubr4,Il10,Lmo4,Casp4,Ogfr,Birc3,Rnf14 |
| 2.083e-25 | -56.83 | HECKER_IFNB1_TARGETS | MSigDB lists | HECKER_IFNB1_TARGETS | 80 | 42 | 15632 | 1249 |
Oas3,Apobec3,Ccl12,Ifit1bl1,Ifit2,Eif2ak2,Parp9,Dhx58,Rsad2,Samd9l,Egr2,Ifi44,Stap1,Dtx3l,Isg15,Rtp4,Ddx58,Egr1,Ddx60,Pnpt1,Zbp1,Lap3,Irf7,Ifit3,Ifit1bl2,Parp12,Xaf1,Oas2,Oas1a,Plscr1,Mmp25,Cxcl10,Ifit3b,Oasl1,Mmp9,Stat1,Oas1g,Herc6,Ifi35,Cmpk2,Epsti1,Sh3bgrl2 |
| 2.298e-25 | -56.73 | negative regulation of cell death | biological process | GO:0060548 | 1051 | 166 | 20694 | 1406 |
Bcl2a1b,Kdr,Stxbp1,Cacybp,Cited2,Daxx,Plk3,Tnf,Cx3cl1,Fzd1,Jun,Rffl,Sod2,Kitl,Met,Angpt1,Nck1,Bfar,Fcgr2b,Pim2,Asah2,Abcc1,Eya4,Ccl12,Casp8,Ciapin1,Cdkn1a,Phip,Igf1r,Mtdh,Hk1,Icam1,Serpinb9,Ccl5,Cdkn2d,Irs2,Ednrb,Nqo1,Insl6,Bnip3,Bcl6,Rnf31,Gclc,Txn1,Il1rn,Cd74,Dusp1,Hif1a,Itga5,Higd1a,Ccnd2,Nes,Kdm4a,Il6,Ptgs2,Bcl2a1d,Cflar,Hspa1b,Prnp,Cd34,Cpeb4,Hsph1,Plk2,Cd38,Tax1bp1,Mt1,Thbs1,Casp2,Rel,Ikbkg,Casp3,Itgav,Htr2b,Itpr1,Psmd10,Prkce,Nr4a3,Clcf1,Tnfsf14,Ahr,Nfkb1,Ncoa7,Slc7a11,Cav1,Chst11,Sirt1,Mmp9,Ier3,Arel1,Arf4,Mdm2,Btg2,Pim3,Il1b,Axl,Grina,Socs3,Rnf34,Abcb1a,Mecp2,Eif2ak2,Adora2a,Pdpn,Stat5a,Pf4,Slc9a1,Hdac1,Glrx,Map2k4,Tnfsf4,Acvr1,Plaur,Nr4a1,Il10,Cx3cr1,Birc3,Birc2,Edn1,Serpinb2,Dnaja1,Fas,Csf1,Nupr1,Nod2,Spry2,Serpine1,Pdgfrb,Myc,Gclm,Ptk2,Sgk3,Arg2,Traf2,Stk40,Src,Bcl2a1a,Stat3,Hck,Csf3,Clec5a,Egr3,Peli1,Asns,Nr3c1,Map4k4,Map2k1,Hcls1,Prdx5,Jak2,Timp1,Sphk1,Hmox1,Cd200,Pim1,Adar,Tnfaip3,Hk3,Il18,Tnfrsf1b,Zc3h12a,Plac8,Optn,Notch1,Chmp4b,Trip10,Prokr1 |
| 2.714e-25 | -56.57 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_UP | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_UP | 168 | 61 | 15632 | 1249 |
Met,Usp12,Ampd3,Akt3,Procr,Nfkb1,Dcun1d3,Rabgef1,Pmepa1,Agpat4,Trem1,Ccl4,Ier3,Acsl1,Tnip3,Acvr1b,Socs3,Scarf1,Il6,Kcnj2,Trip10,Ets2,Bcl2a1b,Sod2,Gramd1a,Trim36,Nfkbia,Plau,Pfkfb3,Fpr2,Tnfsf15,Tmeff1,Osm,Pde4b,Il1b,Ptges,Plaur,Clic4,Serpinb2,Cxcl1,Bcl2a1a,Acsl5,Il2rg,Ptgs2,Osgin2,Ak4,Zc3h12a,St3gal1,Bcl2a1d,Ccnd1,Itgb8,Cish,Nr3c1,Ehd1,Tnf,Slc25a37,Irak3,Myo10,Sav1,Upp1,Il1a |
| 2.873e-25 | -56.51 | positive regulation of catalytic activity | biological process | GO:0043085 | 1269 | 188 | 20694 | 1406 |
Pml,Ccl12,Rasgrp1,Pik3r5,Angpt1,Jun,Fam162a,Tnf,Mapkbp1,Daxx,Ccl3,Tpx2,Ric1,Syk,Ccl4,Cd74,Tlr1,Tbc1d1,Malt1,Nod1,Ccl5,Icam1,Map3k6,Fgr,Cd40,Adora2b,Rgs3,Hsph1,Rapgef2,Plscr1,Tank,Mmd,Abr,Higd1a,Acsl1,Lgals9,Pik3r6,Arf4,Ccl22,Sirt1,Cav1,Lyn,Tbc1d13,F11r,Htr2b,Lmo4,S100a8,Ppp1r15b,Map2k4,Aim2,Atp2b4,Cenpe,Rhoc,Dtx3l,Gclm,Gadd45g,Adap2,Mtcp1,Nod2,Pkp4,Lrp8,Fas,Dnaja1,Stap1,Edn1,Elmod2,Casp1,Casp4,Map4k4,Cdc42ep2,Mul1,Ripk2,Irgm2,Nos2,Tab2,Nek6,Traf2,Rgs1,Sele,Irak2,Il18,Pim1,Uaca,Cdkn1a,Casp8,Gch1,Sdc4,Ift57,Tnfsf10,Met,Cacna1d,Kitl,Arhgap26,Cx3cl1,Mdfic,Il1rn,Il12b,Agrn,Mefv,Gadd45b,Mmp25,Gdf15,Tor1aip2,Ppp1r15a,Egr1,Tagap,Rgcc,Dnajb4,Bmp2,Thbs1,Prnp,Plek,Cflar,Psme2,Ccnd2,Trib3,Pmaip1,Il1b,Mlkl,Pdgfc,Psme1,Ccnd1,Cdk5r1,Prkce,Psmd10,Asap3,Ikbkg,Fcgr1,Adrb2,Arrdc4,Tlr9,Apaf1,Ccl2,Ppm1k,Map3k8,Ccl7,Eif2ak2,Phactr4,Dcun1d3,Ptk2,Ccl9,Nr1h3,Pde5a,Myc,Ccl8,Htr2a,Fzd5,Pdgfrb,Dcp1a,Spry2,Dnajb2,Dennd1b,Csf1,Dock4,Hspa2,Tor1aip1,Antxr1,Sipa1l1,Fpr2,Dock10,Map2k1,Cox17,Src,Stat3,Bcl2l11,Lpar1,Tnfsf15,Dnaja2,Pdgfb,Flt1,Ptafr,Rgs14,Zc3hav1,Ahsa1,Ranbp2,Nlrp3,Trib1,Cycs,Rictor,Cd200,Ripk3,Rin2,Rap1gap2,Crkl,Tlr6,Jak2,Stat1,Nlrc4 |
| 3.116e-25 | -56.43 | NOD-like receptor signaling pathway | KEGG pathways | mmu04621 | 169 | 64 | 7931 | 713 |
Nod1,Il18,Ifnb1,Tab2,Gbp2b,Card6,Itpr1,Il1b,Ripk2,Ripk3,Oas1a,Ikbkg,Myd88,Tank,Nod2,Rnf31,Gbp3,Ifna6,Cxcl1,Ifna1,Oas1g,Casp4,Ifna2,Tnf,Ifi204,Irf7,Nlrc4,Nfkbia,Casp8,Ikbke,Traf2,Ccl2,Tnfaip3,Ccl5,Nampt,Aim2,Gsdmd,Gbp7,Oas1b,Birc3,Il6,Stat2,Nox1,Ifna4,Ccl12,Antxr1,Cxcl3,Jun,Tyk2,Nfkb1,Mefv,Txn1,Stat1,Oas3,Oas2,Nfkbib,Ifnar1,Casp1,Birc2,Ifna5,Gbp2,Cxcl2,Nlrp3,Traf5 |
| 3.116e-25 | -56.43 | NOD-like receptor signaling pathway | KEGG pathways | ko04621 | 169 | 64 | 7931 | 713 |
Itpr1,Il1b,Tab2,Card6,Gbp2b,Ikbkg,Myd88,Ripk2,Oas1a,Ripk3,Rnf31,Tank,Nod2,Ifna6,Gbp3,Il18,Nod1,Ifnb1,Ifi204,Tnf,Nlrc4,Nfkbia,Irf7,Traf2,Ikbke,Casp8,Ifna1,Cxcl1,Oas1g,Casp4,Ifna2,Nox1,Ifna4,Il6,Stat2,Ccl12,Antxr1,Ccl2,Tnfaip3,Ccl5,Nampt,Oas1b,Aim2,Gbp7,Gsdmd,Birc3,Casp1,Nfkbib,Ifnar1,Oas3,Oas2,Birc2,Ifna5,Cxcl2,Gbp2,Nlrp3,Traf5,Cxcl3,Nfkb1,Tyk2,Jun,Stat1,Mefv,Txn1 |
| 4.013e-25 | -56.17 | DER_IFN_GAMMA_RESPONSE_UP | MSigDB lists | DER_IFN_GAMMA_RESPONSE_UP | 85 | 43 | 15632 | 1249 |
Il6,H2-Q4,Adar,Ifi207,Tap1,Fas,Ifi214,Trim21,Ifi211,Plscr1,Ifi203,Psmb8,Ifit3,Mndal,Plod2,Casp8,Ifi35,Stat1,Ifi204,Irf1,Ifit3b,Cycs,Cebpd,Ifit2,Ifi213,Psmb9,H2-Q6,Ifi209,Ifi205,Rhoc,Psme1,H2-Q7,Pml,Icam1,Isg15,Psmb10,Trim26,Ifi208,Phlda1,Nmi,Vegfc,Il15ra,Sp110 |
| 4.577e-25 | -56.04 | GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_DN | 180 | 63 | 15632 | 1249 |
P2ry2,Ogfr,Casp8,Ikbkg,Rnf14,Nfkbib,Cacnb3,Irf1,Rcsd1,Rab20,Tlr9,Lrrc8c,Dnaja1,Tiparp,Ptpn2,Morc3,Gadd45b,Nfkbia,Agrn,Ankrd24,Parp14,Il4i1,Etv3,Sass6,Nfkbiz,Usp25,Chmp4b,Rnd3,Lcp2,Cd274,Atp6v1d,Csrp1,Il12rb1,Oas2,Tbc1d13,Sap30,Tlr1,Ptgs2,Phyh,Trib3,Pim1,Serpinb9,Dnaja2,Il15ra,Epsti1,Keap1,Mitd1,Arid5a,Klf6,Tnf,Ogfrl1,Ccng2,Fut8,Upp1,Tab2,Cd180,Slco3a1,Gbp3,Ch25h,Pml,Hck,Rhoc,Myd88 |
| 4.904e-25 | -55.97 | GSE17721_CTRL_VS_POLYIC_6H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_6H_BMDC_DN | 191 | 65 | 15632 | 1249 |
Mtdh,Ddx4,Clcf1,Cd300lf,Wdr43,Xcr1,Frmd6,Vrk2,Cav1,Irf8,Sema3c,Nos2,Cep350,Pdss1,Timeless,Mapkapk2,Usp25,Stxbp1,Palld,Kat2b,P2ry14,Gng11,Olr1,Crbn,Sod2,Rnf114,Ets2,Irgm2,Stard5,Ppp2r5a,Mmp14,Dusp2,Cox17,Chic2,Arid5b,Ralgds,Gca,Epsti1,Ptges,Keap1,Igsf9,Nampt,Asns,Rilpl1,Icosl,Stxbp3,Snx2,G3bp2,Tyk2,Oas2,Calcrl,Agtrap,Fabp3,Gbp3,Mcmbp,Plagl2,Gbp2,Ehd1,Plekhf2,Ddhd1,Arhgef3,Homer1,Oaf,Lztfl1,Acvr1 |
| 5.677e-25 | -55.83 | GSE10325_BCELL_VS_LUPUS_BCELL_DN | MSigDB lists | GSE10325_BCELL_VS_LUPUS_BCELL_DN | 186 | 64 | 15632 | 1249 |
Xaf1,Plscr1,Psme2,Isg20,Lap3,Cav1,Ifit3,Vrk2,Rgs1,Gfpt1,Cflar,Ifit3b,Ell2,Stat1,Oasl1,Ifi35,Kpna3,Optn,Chst11,Ctsc,Tiparp,Bcl2l11,Dhrs9,H2-Q4,Ifit1bl1,Eif2ak2,Tap1,Adar,Rtp4,Sdc1,Lrp8,Fas,Ddx60,Oas2,Rapgef2,Wars,Nmi,Slc7a5,Ube2l6,Irf7,Ifit1bl2,Ccr1,Nampt,Slc31a2,Glrx,Inpp1,Sec24a,Slc43a3,Dusp5,Herc6,Rsad2,Psma6,Ifi44,Cycs,Sat1,Oas3,Psmb9,H2-Q6,Txnrd1,Cd38,Isg15,Usp18,H2-Q7,Psme1 |
| 7.052e-25 | -55.61 | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | 150 | 57 | 15632 | 1249 |
Tnfrsf8,Isg15,Dtx3l,Agtrap,Usp18,Stat2,Ddx58,Pml,Psme1,Tlk2,Ifi209,Ifi205,Oas3,Ifi213,Phf11b,Sp110,Cmpk2,Cmklr1,Usp42,Oas1g,Herc6,Parp12,Ifi208,Irf7,Col11a2,Ppm1k,Ifit1bl2,Angpt1,Phf11c,Ifi207,Phf11a,Adar,Ifi214,Trim13,Ddx60,Parp9,Parp14,Rhof,Tmem200b,Ifit1bl1,Eif2ak2,Ifit3b,Ifi204,Phf11d,Oasl1,Stat1,Ifi35,Ifi203,Tdrd7,Oas1a,Plscr1,Psme2,Trim21,Ifi211,Mndal,Mov10,Ifit3 |
| 7.400e-25 | -55.56 | regulation of transferase activity | biological process | GO:0051338 | 882 | 147 | 20694 | 1406 |
Zfp36,Fzd5,Ptpn2,Pdgfrb,Htr2a,Gadd45g,Myc,Irak3,Pde5a,Dtx3l,Ptk2,Dusp16,Edn1,Stap1,Dnaja1,Prkar2b,Lrp8,Csf1,Mtcp1,Nod2,Spry2,Ccng2,Tlr9,Arrdc4,Adrb2,Slamf8,Fcgr1,Map2k4,Cenpe,Atp2b4,Dcun1d3,Eif2ak2,Adora2a,Socs1,Map3k8,Il18,Irak2,Rhoh,Ranbp2,Rgs14,Errfi1,Jak2,Tlr6,Crkl,Ripk3,Cd200,Pim1,Adar,Tnfaip3,Trib1,Src,Map4k4,Map2k1,Ptprj,Fpr2,Ccne1,Flt1,Traf2,Pdgfb,Nek6,Spred1,Mvp,Tab2,Tnfsf15,Irgm2,Mul1,Ripk2,Lpar1,Actb,Malt1,Dusp4,Gdf15,Aida,Gadd45b,Spred3,Tlr1,Il1rn,Agrn,Il12b,Cd74,Parp3,Wars,Cd40,Rbl1,Igf1r,Map3k6,Fgr,Rgcc,Egr1,Cdkn2d,Kat2b,Irs2,Uchl1,Met,Angpt1,Nck1,Pik3r5,Sdc4,Ccnj,Rasgrp1,Pml,Cdkn1a,Dusp6,Ubash3b,Syk,Tpx2,Nlrc5,Daxx,Mdfic,Tnf,Mapkbp1,Kitl,Sirt1,Pdgfc,Mlkl,Hhex,Pik3r6,Il1b,Trib3,Lgals9,Ikbkg,Casp3,Htr2b,Lmo4,Cdk5r1,Psmd10,Ccnd1,Cav1,Lyn,Ppp2r5a,Dusp5,Prnp,Rapgef2,Fam72a,Hsph1,Thbs1,Dusp2,Bmp2,Rap2c,Dusp1,Acsl1,Higd1a,Ccnd2,Il6,Dusp8,Ksr1,Mmd |
| 7.493e-25 | -55.55 | regulation of cell population proliferation | biological process | GO:0042127 | 1640 | 223 | 20694 | 1406 |
Ptgs2,Ksr1,Hilpda,Cd80,Atm,Cd86,Adora2b,Spn,Cd38,Sat1,Rapgef2,Clcf1,Ahr,Pbx1,Slc7a11,Il4ra,Osm,Chst11,Lyn,Cav1,Riox2,Ptch1,Itpr1,Htr2b,Cd274,Hhex,Lgals9,Sirt1,Mmp9,Etv3,Il1a,Tnf,Sod2,Jun,Bambi,Cited2,Syk,Stat4,Sh3bp4,Pim2,Taf4b,Parp10,Ago3,Ccl12,Pml,Atf3,Angpt1,Prdm1,Il27,Ccl5,Irs2,Kat2b,Cdkn2d,Nox1,Phip,Igf1r,Cd40,Nlgn2,Cd74,Nos2,Ripk2,Hlx,Htra1,Slfn3,Ptprj,Jarid2,Csf3,Gcnt2,Icosl,Tlr2,Hmox1,Pim1,Marcksl1,Notch1,Slfn2,Pid1,Il18,Itgal,Adora2a,Egln3,Tspo,Bst1,Ptger4,Tnfsf4,Nr4a1,Intu,Il10,Cx3cr1,Dach1,Plau,Irf1,Hdac1,Fas,Nod2,Serpine1,Edn1,Ptgir,Ccr3,Sav1,Morc3,Zfp36,Itga4,Jag1,Cnn2,Cflar,Hif1a,Dusp1,Ccnd2,Il6,Bmp2,Fbxo4,Prnp,Tnfsf9,Thbs1,Lhx2,Nr4a3,Ccnd1,Tnfrsf14,Itgav,Gja1,Casp3,Sla,Hmga2,Il1b,Pmaip1,Pttg1,Pdgfc,Btg2,Mdm2,Cx3cl1,Kitl,Kdr,H2-Aa,Sdc4,Fcgr2b,Pla2g4a,Etv5,Nampt,Cdkn1a,Myd88,Acvrl1,Ift57,Nck1,Rgcc,Sinhcaf,Egr1,Calcrl,Notch2,Vcam1,Il12b,Ccdc88b,Ednrb,Bcl6,Arg2,Ptafr,Mafg,Cxcl10,Flt1,Lif,Pdgfb,Map2k1,Hcls1,Stat2,Odc1,Hck,Stat3,H2-Ab1,Peli1,Egr3,Nr3c1,Cox17,Ripk3,Traf5,Cd200,Il12rb1,Ptges,Rictor,Tarm1,Inhba,Tnfaip3,Trib1,Errfi1,Spint2,Stat1,Timp1,Jak2,Crkl,Sphk1,Akt3,Rnf139,Tnfrsf1b,Abcc4,Optn,Plac8,Slfn1,Eif2ak2,Pdpn,Stat5a,Cxcl1,Tnc,Eef1e1,Vegfc,Mecp2,Ccl2,Tlr9,Nfkbia,Adrb2,Pf4,Il15,Csf1,Nupr1,Dnajb2,Spry2,Col18a1,Zeb1,Kdm5b,Ptk2,Pdgfrb,Ptpn2,Fzd5,Htr2a,Pde5a,Myc |
| 8.140e-25 | -55.47 | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | 171 | 61 | 15632 | 1249 |
Ifit3b,Mafg,Lyn,Rcn1,Parp11,Phf11d,Oasl1,Stat1,Ptk2,Cdkn1a,Ldlr,Zcchc2,Lap3,Ifit3,Etv6,Xaf1,Oas1a,St3gal5,Plscr1,Ksr1,Usp25,Ddx60,Phf11c,Zbp1,Pnpt1,Phf11a,Adar,Znfx1,Eif2ak2,Ifit1bl1,Samd9l,Parp9,Nod2,Rin2,Parp14,Usp42,Oas1g,Hmox1,Herc6,Snn,Epsti1,Fmnl2,Irf7,Ifit1bl2,Rgl1,Oas2,Parp12,Ext1,Dtx3l,Isg15,Stat2,Upp1,Usp18,Mthfr,Pml,Ncoa7,Rbbp8,Oas3,Phf11b,Dhx58,Rsad2 |
| 9.180e-25 | -55.35 | GSE41867_DAY15_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP | MSigDB lists | GSE41867_DAY15_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP | 182 | 63 | 15632 | 1249 |
Sik3,Clec4n,Tdrd7,Ccrl2,Csf1,Isg20,Slc9a1,Tlr2,Pik3cd,Lyn,Stat1,Ccl4,Znfx1,Gpr18,Plac8,Nat2,Irgm2,Parp14,Rtp4,Gmppb,Plagl1,Ddx60,Evl,Samhd1,Rbm43,Zbp1,Sgcb,Irf7,Asah2,Cd86,Pde4b,Oas2,Stx11,Il18,Herc6,Trafd1,Cmpk2,Epsti1,Gca,Oas3,Otud1,Itpr1,Dse,Gypc,Parp8,Stk40,Dhx58,Rsad2,Tapbp,Setdb2,Socs1,Trim12c,Dtx3l,Sertad3,Ddx58,Spata13,Rab19,Stat2,F11r,Zfp513,Itga4,Ncoa7,Mapkbp1 |
| 1.012e-24 | -55.25 | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP | 156 | 58 | 15632 | 1249 |
Egr1,Nfkbiz,Nlrp3,Sgms2,Pim3,Jun,Ets2,Dusp2,Spry2,Gclm,Adrb2,Ier3,Dnajb4,Tnip3,Cflar,Ppp1r15b,Gem,Il10,Pdss1,Srxn1,Csf1,Egln3,Ccrl2,Usp12,Csrnp1,Plk3,St3gal6,Il1a,Upp1,Sav1,Usp53,Txnrd1,Dusp1,Tnf,Homer1,Ubtd2,Dusp5,Zc3h12a,Nsmaf,Il18,Map3k8,Ptgs2,Osgin2,Cxcl1,Snapc1,Il1b,Plaur,Txn1,Plek,Cd274,Asns,Tnfsf15,Arl5b,Slc7a5,Ddit4,Cxcl2,Rapgef2,Inhba |
| 1.038e-24 | -55.22 | BOWIE_RESPONSE_TO_TAMOXIFEN | MSigDB lists | BOWIE_RESPONSE_TO_TAMOXIFEN | 26 | 24 | 15632 | 1249 |
Ifi214,Isg15,Ifi207,Ifit1bl1,Ifi213,Ifit2,Ifi209,Ifi205,Ifi35,Oas1g,Stat1,Ifi204,Irf1,Ifit3b,Ifit1bl2,Ccl5,Ifit3,Mndal,Irf7,Ifi211,Ifi208,Oas1a,Oas2,Ifi203 |
| 1.059e-24 | -55.20 | PHONG_TNF_TARGETS_UP | MSigDB lists | PHONG_TNF_TARGETS_UP | 60 | 36 | 15632 | 1249 |
Icam1,Atf3,Ier2,Egr1,Lif,Tnfaip3,Sdc4,Plau,Cd83,Bmp2,Fos,Ets2,Jun,Birc2,Dusp1,Nfkbia,Klf6,Cebpd,Dusp8,Egr2,Il6,Irf1,Ier3,Dusp5,Cxcl1,Tnfaip2,Ldlr,Nfkb2,Rel,Plk2,Gem,Junb,Birc3,Inhba,Cxcl2,Zfp36 |
| 1.119e-24 | -55.15 | GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_DN | MSigDB lists | GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_DN | 188 | 64 | 15632 | 1249 |
Ehd1,Txnrd1,Timp1,Eno1,Slc2a1,Rab21,Nr3c1,Errfi1,Cebpd,Gsr,Ch25h,Mcoln2,Cd180,Zfp281,Hif1a,St3gal6,Arg2,Socs1,Cd164,Tsku,Ccr1,Junb,Tuba4a,Gch1,Cd86,Noc4l,Ptger4,Hmox1,Pcgf5,Adora2b,Pim1,Map3k8,Il2rg,Nr4a3,Cxcl10,Cldnd1,Ccl12,Cited2,Ets2,Tiparp,Jun,Gclm,Ikzf1,Fcgr2b,Ccl2,Vcan,Gadd45g,Nfkbiz,Cdkn2d,Aff1,Casp4,P2ry2,St3gal5,Plscr1,Zfp36,Itga5,Il13ra1,Lpar1,Irf1,Map2k4,Clcn7,Jak2,Rbms1,Ccl4 |
| 1.164e-24 | -55.11 | GO_RESPONSE_TO_TYPE_I_INTERFERON | MSigDB lists | GO_RESPONSE_TO_TYPE_I_INTERFERON | 71 | 39 | 15632 | 1249 |
Isg15,Stat2,Egr1,Irf2,H2-Q7,Ifna2,Samhd1,Gbp2,Adar,Ifna1,Oas3,H2-Q6,Ifnar1,Ifit1bl1,H2-Q4,Ifit2,Rsad2,Ifnb1,Ifna5,Irf4,Ifit3b,Irf1,Stat1,Oas1g,Oasl1,Ifi35,Ikbke,Irf7,Ifit3,Irf8,Ifit1bl2,Psmb8,Xaf1,Oas2,Tyk2,Trim56,Oas1a,Ifna6,Isg20 |
| 1.277e-24 | -55.02 | HALLMARK_ALLOGRAFT_REJECTION | MSigDB lists | HALLMARK_ALLOGRAFT_REJECTION | 205 | 67 | 15632 | 1249 |
Inhba,Il12rb1,Wars,Icosl,Tlr1,H2-Aa,Lcp2,Tap2,Cd86,Irf7,Ccr1,Ccl5,Il1b,Pf4,Il12b,Il18,Il2rg,Tlr3,Ripk2,Tapbp,Ly75,H2-Q6,Timp1,Traf2,Cd40,Tnf,Gbp2,Icam1,Hif1a,Cd74,Fgr,Socs1,Psmb10,H2-Q7,Lif,Stat4,Il18rap,Csf1,Itgal,Il10,Irf8,Nos2,Jak2,Ccl4,Hcls1,Tlr2,Lyn,Mmp9,Stat1,Fcgr2b,Irf4,Igsf6,Il6,Ccl2,H2-Q4,Ccl12,Tap1,Il15,Cd80,Ccnd2,Ccl22,Nlrp3,Il4ra,Rars,Fas,Nck1,Tlr6 |
| 1.374e-24 | -54.94 | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | 469 | 108 | 15632 | 1249 |
Rnf19a,Sh3bgrl2,Il13ra1,Edn1,4932438A13Rik,Tra2a,Ifit1bl1,Hivep2,Tagln,Zyx,Jun,Herc3,Rnd3,Nfkbiz,Egr1,Sgms2,Xrn1,Btg2,Scn1b,Rgl1,Ifit1bl2,Slc4a7,Junb,Nampt,Slc31a2,Sesn3,Map4k4,Plk2,Myo1b,Elmod2,Dio2,Cd55,Kdm6b,Ptger4,Tgfbi,Rab9,Kdm5b,Acvr1,Parp8,Dusp1,Plekhf2,Dse,Crim1,Rhoc,Dtx3l,Trim12c,Slc9a1,Ppp4r2,Egln3,Rap1gap2,Ppp1r15b,Rbms1,Tax1bp1,Dnajb2,Pmepa1,Frmd6,Cdkn1a,Cpeb4,Dram1,Uaca,Trib1,Parp14,Optn,Parp9,Dusp4,Mid1,Pde5a,Gramd1a,Cnn2,Klf3,Itgav,Sqstm1,B4galt4,Cited2,Lpcat2,Ahr,Me1,Ddx60,Palld,Kat2b,Ddit4,Ext1,Rapgef2,Sh3bp4,Parp12,Gdf15,Csrp1,Myadm,Vps54,St3gal1,Osgin2,Fcho2,Rcan1,Map3k8,Arid5b,Itgb8,Cdyl2,Glipr2,Errfi1,Ccng2,Klf6,Abcc5,Phldb1,Traf5,Ncoa7,Csrnp1,Zfp281,Rnd1 |
| 1.421e-24 | -54.91 | regulation of cellular component movement | biological process | GO:0051270 | 1020 | 161 | 20694 | 1406 |
Cxcl10,Flt1,Ptafr,Spred1,Pdgfb,Tmod3,Lpar1,Lrch1,Gcnt2,Stat3,Src,Sema3c,Map4k4,Mtus1,Ptprj,Map2k1,Dock10,Kcnj2,Hap1,Fpr2,Timp1,Jak2,Spint2,Sphk1,Crkl,Rnd3,Ddx58,Gpr18,Cd200,Ripk3,Tlr2,Hmox1,Trib1,Swap70,Zc3h12a,Il18,Notch1,Akt3,Sele,Cmklr1,Bst1,Mecp2,Plpp3,Vegfc,Ptger4,Pdpn,Glipr2,Stat5a,Ccl2,Plau,Igsf8,Slamf8,Evl,Acvr1,Tnfsf4,Dach1,Cx3cr1,D1Ertd622e,Stap1,Edn1,Sema4c,Csf1,Fas,Dock4,Carmil1,Serpine1,Tmsb10,Spry2,Col18a1,Nod2,Pla2g7,Flrt2,Pdgfrb,Svbp,Itga4,Myc,Prag1,Rhoc,Prkx,Ptk2,Mmp14,Hif1a,Itga5,Acvr1b,Dusp1,Atm,Ptgs2,Cnn2,Jag1,Syne2,Abr,Pik3cd,Thbs1,Rapgef2,Plk2,Spn,Rap2c,Bmp2,Adora2b,Sema4a,Itgav,Lmo4,Rhof,Myadm,Tnfsf14,Nr4a3,Prkce,Lyn,Cav1,Tnfrsf14,Sell,Pdgfc,Mmp9,Sirt1,Mdm2,Il1b,Ppp2r3a,Cd274,Lgals9,Fubp1,Ccl4,Kdr,Cited2,Cx3cl1,Zswim4,P2ry2,Il1a,Kitl,Rffl,Sod2,Jun,P2ry12,Acvrl1,Myd88,Angpt1,Met,Nck1,Rras2,Ccl12,Sdc4,Abcc1,Ccr1,Spata13,Cxcl14,Fgr,Clic4,Igf1r,Cd40,Ccl5,Rabgef1,Egr1,Rgcc,Icam1,Sinhcaf,Irs2,Pde4b,Bcl6,Rnd1,Agrn,Il1rn,Cd74 |
| 1.478e-24 | -54.87 | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP | 178 | 62 | 15632 | 1249 |
Lacc1,Thbs1,Clic4,Ikbke,Il12b,Map3k8,Ptafr,Rnf19b,Ptprj,Vasp,Slc2a6,Gpr132,Samsn1,Ppm1k,Gch1,Pde4b,Tnfaip3,Hck,Plagl2,Sla,Rnd1,Pigv,Ifih1,Tab2,Marcksl1,Parp10,Psma6,Itgb8,Birc2,Serp1,Cd40,Plekhf2,Ehd1,Tnfaip2,Tnip1,Rap2c,Fscn1,Pik3cd,Acsl1,Irf1,Oasl1,Socs3,Atxn7l1,Tifa,Plscr1,Birc3,Klf7,Cdc42ep2,Adar,Sdc4,Pfkfb3,Fpr2,Dcp2,Bcor,Nfkbiz,Rin2,Il4i1,Kcnj2,Ikzf1,Dnaja1,Pik3r5,Plac8 |
| 1.478e-24 | -54.87 | GSE360_CTRL_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_CTRL_VS_M_TUBERCULOSIS_DC_DN | 178 | 62 | 15632 | 1249 |
Ifrd1,Vcan,Pdpn,Sqstm1,Agrn,Nfkbia,Olr1,Cd80,Pfkfb3,Arl4a,Lrp8,Rasgrp1,Slpi,Sik3,Marco,Il10,S100a8,Ccl4,Tnip1,Tnfaip2,Rgs1,Fscn1,Rbms1,Ier3,Lyn,Gpd2,Acsl1,Adrb2,Trib1,Ell2,Mmp9,Tapbp,Gsr,Ifi44,Stat3,Casp1,Ifit2,Relb,Gbp2,Cd38,Crlf3,Cd83,Traf1,Stat2,Icam1,Stx11,Oas2,Wars,Nrp2,Lcp2,Fcgr4,Txn1,Trafd1,Acp2,Tnfsf10,Il1rn,Il2rg,Nr4a3,Ak4,Ldha,Dusp5,Rnf19b |
| 1.583e-24 | -54.80 | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | 671 | 135 | 15632 | 1249 |
Zscan29,Il18rap,Ifi211,Casp8,Lmo4,Mndal,S100a8,Tnfrsf1b,Mob3c,Cdkn1a,Nfil3,Gfpt1,Gbp2b,Ifi204,Ifit3b,Mthfd2,Sema4c,Cpeb4,Ifrd1,Dusp4,Slfn8,B4galt4,Syk,Ass1,Psip1,Itgav,Bcl2a1b,Sqstm1,Ifi207,Me1,Sgcb,Phf11a,Fpr2,Kat2b,Ifi214,Bst1,Rapgef2,Ddit4,Wdfy1,Flrt2,Ppp1r15a,Asns,Plek,Dusp6,Gtpbp2,Sec24a,Inpp1,Trib3,Il18,St3gal1,Errfi1,Ogfrl1,Ccng2,B3gnt5,Phgdh,Rab11fip1,H2-Q6,Tcf4,Bcl6,Ifi209,Slc25a37,Phf11b,Plekha5,Rab3ip,Etv5,Plagl2,Sla,F11r,Jag1,Cd69,Ifi203,Ksr1,Plscr1,Ifit3,Mier3,Psat1,Lnpep,Tagap,Tnfaip2,Rcn1,Phf11d,Sema4a,Fam111a,Azi2,Acsl1,Filip1l,Tra2a,Sdc2,Samd9l,Nqo1,Triobp,H2-Q4,Slc7a11,Ccl12,Phf11c,Tap1,Prnp,Arrdc4,Atf3,Wars,Maff,Ube2l6,Phlda1,Ifi208,Myo1b,Arid4a,Nampt,Lacc1,Bcl2a1a,Il1rn,Slfn9,Clic4,Smox,Kdm6b,Cd55,Dusp5,Scyl2,Bcl2a1d,Gpr84,Nr3c1,Carhsp1,Dennd1b,Itpr1,Rgs14,Tank,Ifi205,Cd40,Ifi213,Ehd1,N4bp1,Hck,Stat2,H2-Q7,Mxd1,Pml |
| 1.585e-24 | -54.80 | positive regulation of programmed cell death | biological process | GO:0043068 | 637 | 119 | 20694 | 1406 |
Cdkn1a,Atf3,Casp8,Pml,Ccl12,Pla2g4a,Nck1,Ift57,Tnfsf10,Jun,Sod2,Fam162a,Nsmaf,Tnf,Daxx,Ccl3,Syk,Dusp6,Agrn,Il12b,Gadd45b,Bcl6,Bnip3,Malt1,Nqo1,Notch2,Ifnb1,Nod1,Egr1,Ccl5,Rgcc,Cd40,Nox1,Casp2,Bmp2,Ctsc,Rapgef2,Fam72a,Thbs1,Pik3cd,Prnp,Plscr1,Ifit2,Tnfrsf8,Ptgs2,Atm,Il6,Dusp1,Hif1a,Pmaip1,Il1b,Cd274,Sirt1,Mmp9,Cav1,Lyn,Osm,4930453N24Rik,Cdk5r1,Nr4a3,Casp3,Itpr1,S100a8,Il10,Plaur,Nr4a1,Map2k4,Hdac1,Slc9a1,Adrb2,Apaf1,Tspo,Eif2ak2,Adora2a,Ppp2r1b,Eef1e1,Dcun1d3,Plekhn1,Sav1,Myc,Itga4,Pde5a,Gadd45g,Ptpn2,Plagl2,Pdgfrb,Col18a1,Nfkbid,Nupr1,Hcar2,Fas,Dnaja1,Sp110,Casp1,Casp4,Nr3c1,Phlda1,Src,Bcl2l11,Mul1,Ripk2,Lpar1,Tnfsf15,Klrk1,Traf2,Notch1,Nlrp3,Optn,Tnfrsf1b,Zc3h12a,Il18,Cycs,Inhba,Hmox1,Ripk3,Uaca,Jak2,Stat1,Nlrc4 |
| 1.764e-24 | -54.69 | cytokine-mediated signaling pathway | biological process | GO:0019221 | 298 | 76 | 20694 | 1406 |
Cxcl1,Stat5a,Ccl3,Ccl7,Il1a,Tnf,Socs1,Aim2,Cx3cl1,Syk,Stat4,Iigp1,Ifna2,Ccl4,Ccr1,Cx3cr1,Ccl12,Pf4,Nfkbia,Ifna6,Myd88,Irf1,Ccl2,Gpr35,Ifnb1,Il15,Fas,Egr1,Cxcl2,Csf1,Ccl5,Ccrl2,Csf3r,Cd74,Ccr3,Il13ra1,Ccl9,Il1rn,Il12b,Oas2,Irak3,Ccl8,Ifitm1,Ifna4,Il2rg,Klf6,Pdgfb,Cxcl9,Ebi3,Il6,Acsl1,Ifna5,Cxcl10,Traf2,Stat2,Il18rap,Nmi,Stat3,Osm,Cxcl3,Il4ra,Il12rb1,Irf7,Cxcl11,Ifnar1,Jak2,Stat1,Il15ra,Il1b,Ccl22,Irak2,Cd300lf,Sirt1,Il18,Tnfrsf1b,Ifna1 |
| 1.820e-24 | -54.66 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN | 184 | 63 | 15632 | 1249 |
Cdkn1a,C3,Stat1,Rab20,Ifit3b,Lyn,Acsl1,Rcn1,Irf1,Alas1,Psme2,St3gal5,Gem,Lmo4,Lap3,Ifit3,Hk3,Usp25,Abr,Slc30a1,Nr1h3,Nlrp3,Rai14,Pla2g4a,Cpd,Rin2,Sod2,Dhrs9,Dnaja1,Clic4,Il1rn,Plaur,Rtn1,Dusp5,Slc31a1,Psmb6,Ptafr,Tlr1,Slc2a6,Ube2l6,Fzd1,Stx11,Wars,Inhba,Ccr1,Txn1,Snx10,Irf7,Tap2,Cd86,Myd88,Gbp2,Upp1,Rhoq,Micall2,Phgdh,Psma6,Dhx58,Ogfrl1,Casp1,Txnrd1,P4ha2,Dse |
| 1.820e-24 | -54.66 | GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | 184 | 63 | 15632 | 1249 |
Phf11c,Vcpip1,Phf11a,Adar,Etv3,Dtwd1,Rtp4,Ddx60,Ifrd1,Stap1,Eif2ak2,Ifit1bl1,Armc8,Zcchc2,Phf11d,Ifit3b,Ifi35,Oasl1,Slc39a14,Oas1a,Cd69,Tdrd7,Dcp1a,Xaf1,Trim21,Isg20,Plscr1,Irf8,Il10,Ifit3,Lap3,Lnpep,Cd38,Ddx58,Usp18,Stat2,Isg15,Ifih1,Rsad2,Dhx58,Dennd1b,Fchsd2,Ifi44,Homer1,Oas3,Ifit2,Phf11b,Sp140,N4bp1,Rcl1,Sp110,Ppp2r2a,Snapc1,Larp1,Herc6,Slc31a1,Oas1g,Snx2,Oas2,Parp12,Nmi,Irf7,Ifit1bl2 |
| 1.844e-24 | -54.65 | GSE17721_LPS_VS_POLYIC_2H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_2H_BMDC_UP | 195 | 65 | 15632 | 1249 |
Slc7a11,Adhfe1,Nfkbia,Ccl2,Pdpn,Fcgr2b,P2ry14,Palld,Tlr6,Egr1,Nck1,Pim3,Lmo4,Nfkb1,Egln3,Met,Mmd,Nfkbib,Ampd3,Acsl1,Irf1,Lpar1,Cd200,Denr,Mtdh,Idi1,Tax1bp1,Cacna1d,P4ha2,Dusp1,Klf6,Stk40,Mdm2,Tnfsf8,Ly75,Nr3c1,Traf1,Fam133b,Calcrl,Mcoln2,Itga4,Mdfic,Cd38,Apaf1,Ube2f,Rrs1,Serpine1,Cd86,Brd2,Rgl1,Csf3,Tlr1,Phlda1,Gpr85,Fpr1,Slc31a1,Rnf19b,St3gal1,Tfec,Stip1,Plat,Nfkb2,Plcl2,Vcam1,Il1rn |
| 2.004e-24 | -54.57 | intracellular signal transduction | biological process | GO:0035556 | 1381 | 197 | 20694 | 1406 |
Mlkl,Mdm2,Il1b,Trib3,Mapkapk2,Pmaip1,Casp3,Itgav,Ikbkg,Rhof,Tlr3,Prkce,Ppm1l,Relb,Prnp,Plek,Plk2,Mt1,Rel,Casp2,G3bp2,Dusp1,Nfkb2,Saa3,Lox,Ednrb,Bcl6,Bnip3,Rnd1,Rcan1,Mark2,Rapgef5,Vcam1,Rab10,Calcrl,Myd88,Cdkn1a,Spata13,Pikfyve,Kdr,Bcl2a1b,Sik3,Nlrc5,Mt2,Mdfic,Cacna1d,P2ry12,Tnfrsf1b,Akt3,Rgs14,Jak2,Lcp2,Errfi1,Sphk1,Rab19,Tyk2,Ddx58,Ripk3,Trib1,Rictor,Src,Bcl2a1a,Bcl2l11,Dock10,Map2k1,Fpr2,Cxcl10,Ptafr,Ero1l,Pdgfb,Ikbke,Asb13,Tnfsf15,Pdgfrb,Myc,Htr2a,Rac3,Ptk2,Ccrl2,Rhoq,Dgkh,Ifih1,Nupr1,Dock4,Batf,Slc9a1,Apaf1,Adrb2,Pf4,Tlr9,Nfkbia,Ddit4,Ezr,Socs3,Azi2,Phactr4,Socs1,Rhou,Pdpn,Map3k8,Ier3,Sirt1,Plcl2,Pik3r6,Gpsm2,Axl,Itpr1,Htr2b,Dbnl,Rab32,Ahr,Lyn,Plscr1,Rab9,Tank,Rapgef2,Pik3cd,Rap2c,Adgrl2,Adora2b,Arhgef3,Ralgds,Cyfip1,Atm,Bcl2a1d,Abr,Ksr1,Malt1,Ift22,Tlr1,Map3k6,Cd40,Igf1r,Larp1,Ccl5,Nod1,Rab20,Pik3r5,Ccl12,Rras2,Rasgrp1,Ccr1,Pml,Syk,Tnf,Mapkbp1,Plk3,Ifi204,Jun,Sod2,Il18,Irak2,Rhoh,Adgre4,Uaca,Rnd3,Hmox1,Tlr2,Dyrk2,Cdc42ep2,Map4k4,Casp4,Nfkbil1,Tlk2,Ptprj,Dgka,Xcr1,Traf2,Nek6,Nos2,Mul1,Ripk2,Tifa,Sesn3,Irgm2,Zfp36,Irak3,Sav1,Rhoc,Ccr3,Ptgir,Sgk3,Edn1,Cish,Socs7,Prkar2b,Adap2,Nod2,Adgrg6,Cdc42ep4,Irf1,Rgl1,Map2k4,Cx3cr1,Rab21,Ptger4,Adora2a |
| 2.023e-24 | -54.56 | regulation of cell-cell adhesion | biological process | GO:0022407 | 394 | 89 | 20694 | 1406 |
Malt1,Bcl6,Il1rn,Il12b,Cd74,Ccdc88b,Vcam1,Icam1,Rgcc,Ccl5,Ifnb1,Ikzf1,Nck1,Sdc4,Rasgrp1,Ubash3b,H2-Aa,Cited2,Syk,Tnf,Cx3cl1,Cd83,Cd274,Il1b,Pik3r6,Lgals9,Casp3,Nfkbiz,Nr4a3,Tnfsf14,Myadm,Il4ra,Tnfrsf14,Lyn,Cav1,Prnp,Tnfsf9,Spn,Hsph1,Cd86,Bmp2,Cd80,Il6,Jag1,Il2rg,Ptpn2,Itga4,Myo10,Pde5a,Ptk2,Il15,Nfkbid,Irf1,Ccl2,Adam19,Adrb2,Tnfsf4,Il10,Plpp3,Slfn1,Adora2a,Ap3b1,Socs1,Pdpn,Stat5a,Il18,Fgl2,Itgal,Zc3h12a,Swap70,Nlrp3,Spint2,Jak2,Tarm1,Il12rb1,Tnfaip3,Src,Icosl,Gcnt2,Peli1,Egr3,H2-Ab1,Ass1,Map2k1,Ptafr,Arg2,Piezo1,Hlx,Ripk2 |
| 2.081e-24 | -54.53 | intracellular organelle | cellular component | GO:0043229 | 11712 | 975 | 20747 | 1409 |
AA467197,Sp100,Ctsc,Etv5,Ctu1,Mx1,Stip1,Ch25h,Brwd3,Snapc1,Ciita,Fam72a,Nxf1,Dtx3l,Trim12c,Gbp3,Sp110,Tnfrsf1b,Prkce,Egr2,Jak2,Rrbp1,Znfx1,Rrs1,Rnd1,Hspa2,Plagl2,Tab2,Mycl,Marcksl1,Casp4,Gch1,Stx11,Resf1,Dse,Sh3bp4,Batf,Arl5b,Agtrap,Cxcl14,Mvp,Gm12185,Bcl2a1b,Frmd4a,Clcn7,Rbl1,Magohb,Ptges,Yju2,Ldlr,Irf1,Tmod3,Oasl2,Dync1i2,Ankrd17,Lgals9,Psmb9,Bcor,Ccdc88b,Ripk3,Wdr59,Arg2,Rab20,Snn,Cpd,Mafk,Vasn,B3gnt5,Ccng2,Snx2,Parp3,Rab3ip,Ube2e1,Adhfe1,Plk3,Cenpj,Samhd1,Hap1,Irf2,Psmb8,Cept1,Jdp2,Nsd3,Fubp1,Gbp8,Arrdc4,Bcl2a1d,Il4i1,Klf3,Fas,Rai14,Rap1gap2,Arid5b,Tgtp2,Nmi,Larp1,Tfec,Gsdmd,Phlpp2,Trib1,Fabp7,Dusp5,Intu,Klf6,Brd2,Sik3,Slc37a3,Map2k1,Zfp281,Casp1,Cox17,Rnf19b,Rubcnl,P4ha1,Scyl2,Fnbp1l,Rmdn3,Tgtp1,Optn,Tapbpl,Kpna3,Mcm9,Aff1,Glipr2,Zc3hav1,Apaf1,Fam162a,Fosb,Lpcat2,Slc30a4,Hif1a,Smox,Pigv,Ass1,Dennd1b,Slc31a2,Hspa1a,Pkp4,Oasl1,Hilpda,Pdss1,Rnf24,Gcnt2,Med13,Sertad3,Relb,Helz2,Armc8,Ifi205,Rnaset2a,Cox18,Nfkbil1,Aoah,Ascc3,Ccnd1,4932438A13Rik,Stard7,Slc48a1,Ppp1r15b,Mthfd1l,Ahr,Parp9,Gbp2,Tcea1,Pdlim7,Sqstm1,Ifi211,Ifrd1,Clic5,Mapkbp1,Iigp1,Tmem67,Acp5,Stxbp1,Cpeb4,Dusp14,Slc39a4,Glrx,H2-Q6,Akt3,Notch1,Slc49a4,Rpgrip1l,Slc7a11,Phip,Abcc4,Serpinb6b,Setdb2,Plscr1,Tlr6,Usp18,Rtn1,Mgat1,Nfkb1,Usp31,Nupr1,Igtp,Malt1,Mamld1,Htr2b,Sec24a,Atp11b,Apobec3,Slc25a22,Prdm9,Tlr2,Hinfp,Sphk1,Marcks,Icosl,Rac3,Chst11,Serpine1,Max,Rffl,Ednrb,Acp2,Srgn,Tor1aip2,Mcm6,Aebp2,Cd34,Slc2a1,Birc3,Fchsd2,Ptgs2,Slc9a1,Hp,Tnip1,Dnajb2,Inpp5b,Triobp,Gtpbp2,Acsl1,Fut8,Sav1,Acpp,Traf5,Tshz1,Evl,Zbp1,Riox2,Mcm10,N4bp1,Rhoq,Arid4a,Lrrc8c,Mmp13,Rgs14,Tgfbi,Rhof,Fscn1,Gmppb,Frmd6,Pim1,Kmo,Nlrc5,Zmynd15,Pmepa1,Eya4,Tlr3,St3gal5,Keap1,G3bp2,Gsr,Src,Dync1h1,Dyrk2,Spn,Prkar2b,Gng12,Parp11,Upp1,Tcf4,Dcp1a,Myo1b,Irf8,Mefv,Phf11c,Abtb2,Tmem123,Maml2,Asf1a,Gdf15,Ikbkg,B4galt4,Atm,Dgkh,Prdx1,Mtus1,Myadm,Dtx2,Vps54,Degs2,Filip1l,Rcl1,Kif9,F830016B08Rik,Dr1,Ptpn2,Slfn1,Cdk5r1,Spry2,Slc25a37,Csrnp1,Slc7a5,Trib3,Cnp,Chmp4b,Dnase1l3,Wdr43,Armcx6,Mpp7,Ifi47,Clic4,Rtn2,Rapgef5,Il15,Sirt1,Syne2,Dnaja1,Bnip3,Nlrp3,Crkl,Cd38,Hlx,Rnf34,Ogfr,Zyx,Dst,Hk3,Cep350,Peli1,Ppp4r2,Egr3,Ift57,Taf4b,Myd88,Piezo1,Itpr1,Mosmo,Fam53c,Bmp2,Eef1e1,Igf2bp2,Mndal,Cmpk2,Cebpd,Gramd1a,Prag1,Higd1a,Txn1,Sp140,Cutc,Aftph,Fcgr2b,Mafg,Casz1,Sco1,Pde3b,Mul1,Ifit2,Stau1,Gypc,Trip13,Il1b,Itgav,Tulp3,Phf6,Ift22,Pcx,Errfi1,Tet2,Smg7,Bcl2a1a,Homer1,Zfp945,Sema4c,Nr1h3,Irak3,Ppp2r5a,Trim26,Ric1,Clmp,Prnp,Pmaip1,Eif2ak2,Ust,Hmga1,St3gal3,Plk2,Plpp3,Tlr9,Rbms2,Hk1,Stat3,Dck,Rbbp8,Ago3,Csrp1,Cav1,Atp13a1,Mmd,Lnpk,Ppm1k,Gpr85,Slc44a1,Hmga2,Lap3,Pou3f1,Pfkfb3,Gm4951,Pnpt1,Cst7,Tmem178,Cgas,Gja1,Dusp8,Cd74,Zfp513,Kdm4a,Tmem176b,Idi1,H2-Q4,Plac8,Psme2,Irak2,Ktn1,Bcl9,Car13,Tlr1,Ksr1,Plekhg1,Trmt1l,Actb,Mdfic,Mrpl52,Casp8,Sgms2,Fam241a,Slc31a1,Bcl2l11,Morc3,Zhx2,P2ry12,Clcn5,Rabgef1,Kdr,Ncoa7,Dbnl,Carmil1,Sod2,Dusp2,Serp1,Slfn9,Arhgap26,Ap3m2,Micall2,Smc5,Minpp1,Naa25,Hopx,Birc2,Oas1a,Katna1,Wdfy1,Mid1,Mier3,Sesn3,Rbpms,Tdrd7,Vasp,Uaca,Prpf38a,Tent4a,Lrp8,Spen,Plagl1,Stx6,Prdx5,Adar,Mt1,Flrt2,Timeless,Cdc42ep4,Gpc1,Tomm70a,Hk2,Trim30a,Apba1,Rapgef2,Cnot4,Mmp14,Herc6,Spred1,Lhx2,Ralgds,Parp12,Ikzf1,H2-Ab1,Phf11a,Fcho2,Ifnar1,Bfar,Dusp1,Phf11b,Kdm6b,Stk40,Nox1,Nmral1,Me1,Nr4a1,Rbms1,Shisa3,Rnf19a,Egr1,Sap30,Egln3,Txnrd1,H2-Eb1,Daam1,Zfp40,Tma16,Igf1r,Tbc1d1,1600014C10Rik,Hsph1,Top3a,Fos,Gm5431,Esd,Tspo,Lox,Tasor2,Pml,Kdm5b,Swap70,Pdgfc,Pou2f2,Casp7,Sele,Ccr3,Cop1,Casp2,Etnk1,Cdyl,Uba7,Klf2,P4ha2,Noc4l,Jun,Zeb1,Cyth3,Ccdc86,Flnb,Hspa1b,Slc39a13,Nes,Pcgf5,Ifitm1,Sbds,Treml4,Psmb10,Dnajb4,Irf4,Nampt,Slc4a7,Ubash3b,Xaf1,Cited2,Tra2a,Ddx4,Irf7,Aim2,Tpst1,Sla,F11r,Extl2,Atp6v1d,Ddx60,Osbpl3,Mapkapk2,Ahsa1,Myo10,Lad1,Rab19,Bbx,Ubr4,Zc3h12a,Jarid2,Parp14,Acsl5,Oas1b,Tpx2,Ier2,Pik3r5,Pdgfrb,Gfi1,Atf3,Etv3,Psip1,Cd40,Spata13,Hhex,Dhrs9,Socs7,Cdkn1a,Ak4,Sde2,Tal2,Nfkbid,Alas1,St3gal6,Dennd2a,Edn1,Tent2,Plaat3,Rnf114,Dek,Dpy19l1,Cenpe,Palld,Cdkn2d,Hcls1,Ccnd2,Zup1,Serpina3g,Psma6,P2ry2,Ep400,Fndc3a,Mt2,Zfp36,Cers6,Ifi208,Serpinb9,Ddit4,Coa5,Lcn2,Ifi203,Vrk2,Pikfyve,H2-Q7,Htr2a,Gm4841,9930111J21Rik1,Dennd6b,Psd,Batf2,Tlk2,Ifi35,Calcrl,Pf4,Mxd1,Tap2,Carhsp1,Cd86,Trim21,Parp10,Themis2,Hivep3,Ell2,Zfp319,Pttg1,Uchl1,Gbp2b,Samd9l,Psmd10,Pnp2,Ptk2,Tor1aip1,Polr2g,Nfkb2,Rcan1,Adam19,Dach1,Fgr,Mtdh,Rnf139,Cacna1d,Dusp4,Tuba4a,Atp11a,Golga3,Hivep2,Ifih1,Ets2,Rnf145,Hsd17b12,Aldh1b1,Notch2,Ptger4,Dram1,Ahrr,Trip10,Nos2,Ero1l,Usp25,Kif3c,Tnf,Tnfaip3,Nr4a3,Lipe,Klf7,Mdm2,Gbgt1,Usp12,Atp10a,Rilpl1,Hck,Nfkbib,Itpkc,Shfl,Olr1,Spic,Rel,Stat2,4930453N24Rik,Stat5a,Phlpp1,Cd164,Ranbp2,Pde4b,Arf4,Trim14,Xrn1,Mark2,Stap1,Noct,Zfp800,Sh3bgrl2,Ifit3,Jmjd6,Plekha5,Mthfd2,Slc16a3,Cd14,Rgcc,Ifi204,Bcorl1,Gbp9,Slc29a3,Samsn1,Znrf1,Acod1,Hmgn3,Atp2b4,Radx,Rab11fip1,Kmt5a,Gk,Fam20c,Chic2,Rhbdf2,Wars,Plod2,Grk3,Marf1,Rhou,Casp3,Oas2,Vcpip1,Nt5c3,Phlda1,Ppp1r15a,Dcp2,Tle3,Dmxl2,Fam111a,Flrt3,Cx3cr1,Psmb6,Ifi214,Mdn1,Fignl2,Klf8,Cdyl2,Junb,Snx10,Lacc1,Rgs3,Ppfia3,Ociad1,Cycs,Plat,Rnd3,Cnn2,Pgs1,Mecp2,Ifi209,Stoml1,Thbs1,Nfil3,Pdpn,Mov10,Tnks1bp1,Arid5a,Gadd45b,Il15ra,Sema4a,Gadd45g,Lipg,Rab32,Sgcb,Mtcp1,Myc,Phyh,Plod3,Stxbp3,Ifi207,Usb1,Rnf14,Ciapin1,Dmwd,Maff,Nr3c1,Nfkbiz,Ier3,Slfn5,Gpsm2,Asah2,Ifit3b,Asap3,Crbn,Map2k4,P2ry13,Ccnj,Prpf4,Lpar1,Pdk3,Ccl2,Hsd17b7,Mx2,9130023H24Rik,Kif5c,Hdac1,F10,Slc25a12,Tyk2,Rap2c,Traf2,Ezr,Vezt,Tiparp,Milr1,Nck1,Rab10,Ikbke,Adap2,Mcmbp,Adora2a,Rfx5,Cd274,Agpat4,Trim13,Sass6,Rims3,Kitl,Pgap2,Plekhf2,Etv6,Msr1,Tgs1,Ppp1r12b,Tut7,Kat2b,Mfap3l,Rsad2,Cep85l,Irgm1,Nod2,Chd9,Nfkbia,Dock4,Rab21,Plekhn1,Mppe1,Ddx58,H3f3b,Slc30a1,Oas3,Itga5,Trim36,Cnn3,Sinhcaf,Ldha,Dnaja2,Slamf7,Pbx1,Rhoc,Ccne1,Rcn1,Slc15a3,Mtfr2,Cdc42ep2,Rab9,H2-Aa,Prdm1,Nfxl1,Arl5c,S100a8,Spire1,Tmtc2,Dusp16,Ncoa5,Isg20,Anp32a,Rsbn1,Irgm2,Plekha2,Gpr18,Foxp4,Whamm,Dock10,Gsap,Socs1,Ifi213,Ehd1,St3gal1,Tor3a,Perm1,Psme1,Mitd1,Fzd5,Cacybp,Vcam1,Hat1,Oas1g,Arl4a,Btg2,Tapbp,Kcnj2,Bcl6,Rars,Ripk2,Syk,Caml,Flt1,Zbtb5,Abcc1,Prkx,Slc16a1,Tap1,Pstpip2,Adrb2,Slc25a25,Tpm4,Sipa1l1,Gem,Phf11d,Hmox1,Gbp7,Stat1,Sgk3,Ap3b1,Stat4,Ext1,Pla2g4a,Nfkbie,Ptch1,Nek6,Med21,Procr,Lnpep,Grina,Rnaset2b,Gpd2,Sdc4,Daxx,Sec24b,Lyn,Isg15,Rasgrp1,Crlf3,Mcoln2 |
| 2.168e-24 | -54.49 | GSE6259_CD4_TCELL_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_CD4_TCELL_VS_CD8_TCELL_DN | 158 | 58 | 15632 | 1249 |
Sdc4,Adar,Kat2b,Gpr141,Nr1h3,P2ry14,Usp25,Vcan,Il18bp,Rin2,Pde5a,Slc44a1,Tet2,Cyfip1,Dock4,Klf3,Nlrc5,Chd9,Ifi35,Dtx2,Sirt1,Trim14,Il10,Casp8,Ogfr,Plekha2,Adap2,Casp4,Icam1,Ddx58,Stat2,Rnf135,Irf2,Mxd1,Mdm2,Dhx58,Dbnl,Rab9,Itpr1,Dse,Parp8,Il15ra,Snn,Htr2b,Gtpbp2,Plcl2,Tnfsf10,Prkx,Mob3b,Tgfbi,Frmd4a,Scyl2,Rilpl1,Daam1,Irf7,Atp6v1d,Slc31a2,Arid4a |
| 2.247e-24 | -54.45 | GO_REGULATION_OF_CELL_DEATH | MSigDB lists | GO_REGULATION_OF_CELL_DEATH | 1341 | 214 | 15632 | 1249 |
Tnf,Bcl6,Traf2,Cycs,Hdac1,Nupr1,Cd74,Sgk3,Traf5,Tnfaip3,Gdf15,Ccl5,Dusp6,Asns,Ppp1r15a,Rapgef2,Inhba,Tlr3,Bcl2a1b,Sod2,Sqstm1,Plac8,Eif2ak2,Dnaja1,Ifnb1,Phlpp1,Col18a1,Stxbp1,Nck1,Irs2,Mul1,Ciapin1,Ikbkg,Nfkb1,Dcun1d3,S100a8,Atm,Casp8,Slc9a1,Itga5,Ptk2,Lyn,Jak2,Arf4,Cdkn1a,Casp1,Axl,Dusp1,Timp1,Rffl,Bcl2a1d,Acvr1,Pml,Sphk1,Icam1,Bmp2,Nod1,Ripk3,Daxx,Card6,Map4k4,Txn1,Junb,Tnfsf15,Btg2,Nfkbid,Il12b,Ptgs2,Pim1,Clec5a,Tnfsf10,Bcl2a1a,Hcar2,Ccl12,Cx3cr1,Nfkbia,Jun,Myc,Il6,Spry2,Nqo1,Prnp,Trim13,Phip,Gclc,Rras2,Tnfsf14,Il10,Socs3,Kdr,Hcls1,Igf1r,Ifit2,Arhgef3,Stat3,Prdx5,Mecp2,Plk3,Sav1,Myd88,Rnf34,Plagl2,Apaf1,Cd38,Serpine1,Irf7,Pdgfrb,Osm,Higd1a,Cd274,Ddit4,Hmox1,Ripk2,Hp,Nr4a3,Kitl,Htr2b,Il1b,Itgav,Gadd45b,Cited2,Ptpn2,Nlrc4,Gclm,Ctsc,Bnip3,Pla2g4a,Gadd45g,Ift57,Cdkn2d,Fas,Cx3cl1,Cdk5r1,Tspo,Pim3,Cd34,Tnfrsf1b,Ednrb,Cav1,Rel,Egln3,Mmp9,Pim2,Mtdh,Cpeb4,Egr3,Map2k4,Ifit3b,Lpar1,Ppp2r1b,Tax1bp1,Notch2,Fam162a,Insl6,Src,Hsph1,Cd40,Birc2,Hspa1a,Casp3,Stk40,Mdm2,Malt1,Traf1,Il1a,Hif1a,Tnfrsf8,Bfar,Hck,Notch1,Plk2,Phlda1,Rilpl1,Csf3,Ldha,Zc3h12a,Serpinb9,Nsmaf,Grina,Thbs1,Serpinb2,Acsl5,Pf4,Plaur,Bcl2l11,Psmd10,Prokr1,Edn1,Nod2,Chst11,Egr1,Atf3,Abr,Nlrp3,Adar,Angpt1,Tnfrsf14,Chmp4b,Birc3,Casp4,Ifit3,Cysltr2,Eef1e1,Met,Casp2,Sirt1,Stat1,Casp7,Nox1,Ier3,Adrb2,Clcf1,Cflar,Tmem219 |
| 2.283e-24 | -54.44 | GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS | 153 | 57 | 15632 | 1249 |
Nlrp3,Nr1h3,Tlr6,Plau,Cd80,Tspo,Cx3cr1,Nfkbia,Ass1,Syk,Ccl12,Il6,Stap1,Prkce,Tnip3,Lyn,Tlr2,Tnfsf4,Mtdh,Gfi1,Irf8,Il10,P2ry2,Nos2,Nfkb1,Tnfrsf1b,Ppp1r15b,Ednrb,Nfkbib,Hif1a,Cd180,Icam1,Nfkbil1,Apaf1,Hck,Tnfaip3,Cd14,Cd40,Src,Tnf,Axl,Il18,Ptafr,Il12b,Cxcl10,Zc3h12a,Ripk2,Cmpk2,Il1b,Irak2,Fzd5,Cd86,Serpine1,Pde4b,Ccl5,Csf3,Tlr1 |
| 2.298e-24 | -54.43 | response to lipopolysaccharide | biological process | GO:0032496 | 335 | 81 | 20694 | 1406 |
Zfp36,Cd14,Junb,Malt1,Ednrb,Fcgr4,Irak3,Pde4b,Nr1h3,Ptgir,Il1rn,Il12b,Cd180,Stap1,Mtdh,Tnip3,Cxcl2,Ccl5,Nod2,Serpine1,Ccl2,Noct,Myd88,Nfkbia,Pf4,Gbp2,Tnfsf4,Ccl12,Gch1,Arid5a,Il10,Cx3cr1,Ptger4,Eif2ak2,Tnf,Cxcl1,Jun,Il18,Acp5,Tnfrsf1b,Zc3h12a,Irak2,Nlrp3,Cd274,Il1b,Gfi1,Mapkapk2,Axl,Irf8,Lgals9,Ifnar1,Jak2,Stat1,Acod1,Nfkbib,Prkce,Cxcl11,Cxcl3,Nfkb1,Lyn,Trib1,Tnfaip3,Plscr1,Peli1,Nfkbil1,Cd86,Casp1,Cmpk2,Ptafr,Cxcl10,Cd80,Klrk1,Slpi,Cxcl9,Il6,Tab2,Nos2,Ptgs2,Irgm2,Abr,Ripk2 |
| 2.334e-24 | -54.41 | GO_NEGATIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 138 | 54 | 15632 | 1249 |
Tnfaip3,Isg15,Trim12c,Pml,Nfkbil1,Parp10,Prdm1,Rsad2,Dhx58,Hdac1,Ifi209,Ifi205,Oas3,Timp1,Tnf,Ifi213,Il12b,Oas1g,Zc3h12a,Ifi208,Trim26,Ccl5,Ifit1bl2,Zc3hav1,Ifi207,Adar,Mul1,Ifi214,Trim13,Ifnb1,Jun,Sqstm1,Itgav,Ifit1bl1,Eif2ak2,Ccl4,Tnip1,Fam111a,Ifi204,Trib1,Stat1,Oasl1,Ifi203,Oas1a,Plscr1,Htra1,Slpi,Isg20,Trim21,Trim14,Ifi211,Mndal,Irf8,Il10 |
| 2.552e-24 | -54.33 | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_DN | 185 | 63 | 15632 | 1249 |
Casp7,Tnfsf4,Rab20,Orai2,Whamm,Gfpt1,Tmem67,Tmem219,Lap3,Slpi,Pdss1,Bcl9,Spen,Rasgrp1,Ccdc25,Hivep3,Pikfyve,Lpcat2,Zbtb5,Rbl1,Prpf4,Olr1,Angpt1,Aff1,Trmt1l,Ass1,Fam43a,Spsb1,Hivep2,Trim36,Ezr,Tspan3,Ctsc,Cept1,Ttc39b,Acsl5,Plcl2,Sp110,Zhx2,Gng12,Sipa1l1,Flrt2,Caml,Sh3bp4,Rnf139,Ch25h,Fgr,Agtrap,Arg2,Atp11a,Kmo,Myo10,Rgs3,Apaf1,Ctu1,Ddhd1,Usp53,Itpr1,Swap70,Oaf,Dock10,Tapbp,Mdm2 |
| 2.642e-24 | -54.29 | positive regulation of apoptotic process | biological process | GO:0043065 | 632 | 118 | 20694 | 1406 |
Mul1,Lpar1,Ripk2,Tnfsf15,Klrk1,Traf2,Casp1,Casp4,Nr3c1,Phlda1,Src,Bcl2l11,Cycs,Inhba,Hmox1,Ripk3,Uaca,Jak2,Stat1,Nlrc4,Nlrp3,Notch1,Optn,Tnfrsf1b,Zc3h12a,Il18,Tspo,Eif2ak2,Adora2a,Ppp2r1b,Eef1e1,Dcun1d3,Plekhn1,S100a8,Il10,Plaur,Nr4a1,Map2k4,Hdac1,Slc9a1,Apaf1,Adrb2,Col18a1,Nfkbid,Nupr1,Hcar2,Fas,Dnaja1,Sp110,Sav1,Pde5a,Itga4,Myc,Gadd45g,Ptpn2,Pdgfrb,Plagl2,Ifit2,Tnfrsf8,Ptgs2,Il6,Atm,Dusp1,Hif1a,Casp2,Bmp2,Ctsc,Rapgef2,Fam72a,Pik3cd,Thbs1,Prnp,Plscr1,Cav1,Lyn,Osm,4930453N24Rik,Cdk5r1,Nr4a3,Casp3,Itpr1,Pmaip1,Il1b,Cd274,Mmp9,Sirt1,Jun,Sod2,Fam162a,Nsmaf,Tnf,Ccl3,Daxx,Syk,Dusp6,Atf3,Casp8,Pml,Ccl12,Pla2g4a,Nck1,Ift57,Tnfsf10,Notch2,Ifnb1,Nod1,Egr1,Ccl5,Rgcc,Cd40,Nox1,Il12b,Agrn,Gadd45b,Bnip3,Bcl6,Malt1,Nqo1 |
| 2.834e-24 | -54.22 | regulation of inflammatory response | biological process | GO:0050727 | 336 | 81 | 20694 | 1406 |
Ptger4,Bst1,Socs3,Stat5a,Adora2a,Ccl3,Tnf,Cx3cl1,Tlr9,Adrb2,Nfkbia,Slamf8,Fcgr1,Myd88,D1Ertd622e,Il10,S100a8,Cx3cr1,Siglece,Fcgr2b,Tnfsf4,Pla2g4a,Stap1,Nod2,Calcrl,Serpine1,Rabgef1,Ccl5,Nupr1,Pde5a,Cd200r4,Bcl6,Zfp36,Ptpn2,Ctla2a,Ednrb,C3,Cst7,Mefv,Nr1h3,Il12b,Atm,Il6,Abr,Nos2,Ptgs2,Spn,Smpdl3b,Casp1,Fpr2,Adora2b,Aoah,Ldlr,Ctsc,Tlr3,Nfkbiz,Sphk1,Uaca,Usp18,Jak2,Tlr6,Acod1,Nfkb1,Rictor,Osm,Tarm1,Tnip1,Lyn,Tnfaip3,Tlr2,Clcf1,Cd200,Dnase1l3,Slc7a2,Acp5,Tnfrsf1b,Ier3,Zc3h12a,Lgals9,Nlrp3,Il1b |
| 2.950e-24 | -54.18 | GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_DN | 180 | 62 | 15632 | 1249 |
Calcrl,Ifih1,Hvcn1,Prpf38a,Mdfic,Sav1,Klf6,Parp8,Ifnar1,Plekhf2,Ddhd1,Cst7,Nr3c1,Arid5b,Kif3c,Gpr85,Fam53c,Rcl1,Vegfc,Plaur,Il15ra,Acp2,Ikbke,Plat,Hsd17b12,Nampt,Brd2,Vasp,Pdlim7,Dtwd1,Nxf1,Abr,Ddx60,Atf3,Rars,Tnks1bp1,Me1,Pim3,Rnd3,Cd80,D16Ertd472e,Klf3,Nfkbia,Adhfe1,Itgav,Slc44a1,Peli1,Rai14,Lpar1,Irf1,Lyn,Ebi3,Dusp16,Znrf1,Tor3a,Birc3,Rabgef1,Dach1,Tnfrsf1b,Akt3,Csf1,Nfkbib |
| 3.787e-24 | -53.93 | GSE1432_1H_VS_24H_IFNG_MICROGLIA_DN | MSigDB lists | GSE1432_1H_VS_24H_IFNG_MICROGLIA_DN | 170 | 60 | 15632 | 1249 |
Gclc,Phf11a,Ciita,Tap1,Phf11c,Tnfrsf14,Ddx60,Fas,Pla2g4a,Nod2,Rnf114,Tnfaip2,Chd9,Jak2,Dr1,Stat1,Max,Lyn,Rcn1,Aida,Phf11d,Psme2,St3gal5,Isg20,Psmb8,C1rl,Casp4,Lap3,Crlf3,Mvp,Gbp2,Cd38,Psme1,Trim12c,Sell,Psmb10,Ifih1,Cd74,Dennd1b,Ifi44,Dhx58,C1ra,Sp140,Phf11b,Rhbdf2,Traf2,Psmb9,Tnfsf10,Ralgds,Sp110,Il15ra,Slc31a1,H2-Ab1,Tapbpl,Slamf8,Nmi,Wars,Irf7,Ascc3,Tap2 |
| 4.072e-24 | -53.86 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | MSigDB lists | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | 69 | 38 | 15632 | 1249 |
H2-Q7,Irf2,Egr1,Stat2,Usp18,Socs1,Isg15,Ifna1,Adar,Gbp2,Ifna2,Ifit2,H2-Q4,Ifit1bl1,Ifnar1,H2-Q6,Oas3,Irf4,Ifnb1,Ifna5,Ifi35,Oasl1,Stat1,Oas1g,Socs3,Irf1,Ifit3b,Psmb8,Ifit1bl2,Irf8,Ifit3,Irf7,Isg20,Ifna6,Oas1a,Oas2,Tyk2,Xaf1 |
| 4.149e-24 | -53.84 | GSE17721_CTRL_VS_CPG_4H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_4H_BMDC_DN | 181 | 62 | 15632 | 1249 |
Adhfe1,Sod2,Trmt1l,Znfx1,Stard5,Mmp14,Katna1,Cox17,Vcan,Cpd,Atf3,Palld,Aff1,Me1,Nfkb1,Gbp7,Bcl9,Csf1,Tdrd7,Mtmr14,Etnk1,Ell2,Cd200,Ms4a6d,Mthfd2,Znrf1,Arf4,Notch2,Kdr,Ldlr,Frmd6,Cst7,Gypc,Prdx5,Itga4,Pml,Tab2,Gbp3,Bfar,Myd88,Tnfrsf8,Cutc,Clcn5,Cd38,Prpf38a,Snx10,Pde4b,Txn1,Nampt,Samsn1,Stxbp3,G3bp2,Eya4,Oas2,Il18,Il1rn,Plcl2,Gtpbp2,Cldnd1,Mitd1,Keap1,Ptges |
| 4.581e-24 | -53.74 | regulation of biosynthetic process | biological process | GO:0009889 | 3584 | 390 | 20694 | 1406 |
Maml2,Ezr,Spic,Slc9a1,Tlr9,Pf4,Ell2,Hopx,Cenpj,Mecp2,Zeb1,Dcp1a,Plagl2,Myc,Htr2a,Aff1,Csrnp1,Birc2,Klf2,Sec24a,Hcls1,Tfec,Egr3,Hck,Stat3,Src,Batf2,Mafg,Ptafr,Pdgfb,Klrk1,Ak4,Ranbp2,Mndal,Pou2f2,Maff,Cd200,Ripk3,Trib1,Stat1,Bcor,Prdx5,Nlrc4,Hat1,Gch1,Arid5a,Fcgr2b,Mafk,Serp1,Myd88,Met,Zfp281,Cx3cl1,Mdfic,Cacna1d,Egr2,Kdr,Gfpt1,Nlrc5,Txn1,Kdm6b,Ppp1r15a,Bcl6,Gdf15,Egr1,Rgcc,Notch2,Zhx2,Dnajb4,Eno1,Kmt5a,Rel,Prnp,Fbxo4,Thbs1,Cd34,Prdm9,Mamld1,Jag1,Ciita,Cflar,Sap30,Hif1a,Il6,Kdm4a,Tal2,Hmga2,Pttg1,Fubp1,Mapkapk2,Mdm2,Ccnd1,Nr4a3,Psmd10,Zmynd15,Crlf3,Pcx,Relb,Gja1,Itgav,Ikbkg,Nr4a1,Acvr1,Hinfp,Tnfsf4,Hdac1,Aim2,Adora2a,Ets2,Atp2b4,Mov10,Ptger4,Hivep3,Zfp36,Irak3,Lrp8,Serpine1,Nod2,Nfkbid,Trim21,Xrn1,Nmi,Tnfsf8,Nfkbie,Ass1,Csf3,Icosl,Dyrk2,Gbp4,Nos2,Ifi208,Parp9,Htra1,Notch1,Pid1,Irak2,Pim1,Tlr2,Hmox1,Klf8,Ago3,Pim2,Pml,Brwd3,Prdm1,Ccl3,Ifi204,Sod2,Fzd1,Stat4,Syk,Tlr1,Fabp3,C3,Cd74,Malt1,Junb,Rnf31,Ccl5,Trim14,Jdp2,Nod1,Ifnb1,Nox1,Phip,Tshz1,Ankrd17,Igf1r,Larp1,Psip1,Cdyl,Fam129a,Cd38,Timeless,Ahrr,Fos,Atm,Hhex,Trim13,Acsl5,Irf8,Klf3,Arf4,Ahr,Ifi209,Slc7a11,Ncoa7,Tnip1,Ptch1,Lmo4,Htr2b,Helz2,Mllt6,Batf,Ccl2,Med21,Nfkbia,Dcp2,Adrb2,Gtpbp2,Slfn1,Eif2ak2,Plagl1,Aebp2,Stat5a,Rbpms,Plekhn1,Arid4a,Fosb,Etv6,Kdm5b,Nr1h3,Tle3,Pdgfrb,Cebpd,Fzd5,Ptpn2,Nupr1,Il15,Rhoq,Spen,Ifrd1,Pdk3,Eif4g2,Map2k1,Fpr2,Stat2,Peli1,Nr3c1,Psma6,Wdr43,Arg2,Lif,Nlrp3,Rgs14,Tnfrsf1b,Rnf139,Sp140,Plac8,Ifi211,Ddx58,Hmgn3,Traf5,Inhba,Tnfaip3,Irf7,Tlr6,Jak2,Errfi1,Cdyl2,Sphk1,Tcea1,Pla2g4a,Etv5,Ifi207,Cdkn1a,Phf6,Rbbp8,Nampt,Zfp513,Acvrl1,Nck1,Cacybp,Agrn,Ednrb,Ifi214,Brd2,Bmp2,Zbtb5,Nmral1,Plek,Cpeb4,Lhx2,Tnfrsf8,Perm1,Acvr1b,Dusp1,Nfkb2,Il1b,Trib3,Polr2g,Tet2,Acp5,Btg2,Rfx5,Keap1,Cdk5r1,Nfkb1,Ifnar1,Ifi205,Tlr3,Ppp1r15b,Irf2,Map2k4,Dach1,Cx3cr1,Il10,Klhl25,Irf1,Tspo,Cmklr1,Hspa1a,Plpp3,Sav1,Med13,Irf4,Dtx3l,Nsd3,Hmga1,Edn1,Resf1,Smg7,Ldlr,Il18rap,Ccne1,Ifi203,Jarid2,Hivep2,Nfkbil1,Trim26,Rnf14,Ripk2,Hlx,Znfx1,Traf2,Gfi1,Zc3h12a,Il18,Ythdf1,Foxp4,Nfkbib,Taf4b,Parp10,Sertad3,Atf3,Ikzf1,Mxd1,Il27,Plk3,Tnf,Il1a,Daxx,Pcgf5,Tcf4,Jun,Bambi,Cited2,Gclc,Parp3,Pou3f1,Max,Arid5b,Icam1,Irs2,Jmjd6,Kat2b,Igf2bp2,Dr1,Mtdh,Mycl,Cd40,Rbl1,Rap2c,Nfxl1,Adora2b,Dusp5,Plscr1,Tax1bp1,Hsph1,Rapgef2,Spn,Mier3,Ptgs2,Ifi213,Bcl9,Traf1,Ier2,Casz1,Nfil3,Cyfip1,Klf6,Etv3,Sirt1,Pbx1,Klf7,Cav1,Osm,Acod1,Riox2,Sqstm1 |
| 4.763e-24 | -53.70 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_DN | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_DN | 176 | 61 | 15632 | 1249 |
Il12b,Pim1,Ptgs2,Traf3ip2,Zc3h12a,Il15ra,Slc37a3,Plat,Cxcl1,Bcl2a1a,Snapc1,Samsn1,Cd274,Map4k4,Csf3,Traf1,Socs1,Rnd1,Hlx,Plagl2,Zfp319,Tnfrsf8,Batf,Acpp,Otud1,Slc25a37,Klf6,Bcl2a1d,Itgb8,Stat3,Ier3,Tnip3,Socs3,Ell2,Hmgcs1,Frmd6,P2ry2,Il10,Tnfrsf1b,Abtb2,Stat4,Usp12,Pdss1,Pikfyve,Il4ra,Papss2,Etv3,Fpr2,Enpp4,Ptpn2,Trip10,Mrpl52,Bcl2a1b,Gadd45b,Flt1,Trim36,Plac8,Gramd1a,Il6,Peli1,Pla2g4a |
| 4.976e-24 | -53.66 | GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_DN | 187 | 63 | 15632 | 1249 |
Jak2,Tax1bp1,Dusp16,Lhx2,Nlgn2,Lrrc8c,Pmepa1,Ptk2,Ifi35,Ptgir,Rnf145,Nfkbib,Usp12,Tdrd7,Rasgrp1,Jdp2,Il10,Casp8,Gem,Slc25a25,Prdx1,Rbl1,Peli1,Rai14,Kremen1,Dtnb,Klf3,Nfkbia,Morc3,Cx3cr1,Gramd1a,Psmd10,Dnaja1,Acsl5,St3gal1,Tlr3,Traf3ip2,Ripk2,Gpr85,Serpinb9,G3bp2,Vasp,Dgka,Hsd17b12,Myo1b,Asns,Rrs1,Rnf34,Apaf1,Mdfic,Nupr1,Icam1,Calcrl,Upp1,Sertad3,Nr3c1,Rffl,Prdx5,Tapbp,Src,Usp53,Gpsm2,Csf3r |
| 5.088e-24 | -53.64 | ZHANG_INTERFERON_RESPONSE | MSigDB lists | ZHANG_INTERFERON_RESPONSE | 29 | 25 | 15632 | 1249 |
Ifi214,Isg15,Rtp4,Ifi207,Ifi213,Ifit2,Ifi209,Ifi205,Oas3,Ifi44,Ifnb1,Ifrd1,Stat1,Oasl1,Oas1g,Irf1,Ifi204,Sp110,Mndal,Ifi208,Isg20,Ifi211,Ifi203,Oas2,Oas1a |
| 5.395e-24 | -53.58 | EGFR_UP.V1_UP | MSigDB lists | EGFR_UP.V1_UP | 171 | 60 | 15632 | 1249 |
Apobec3,Psmb9,Homer1,Rhoq,Sat1,Hspa2,Cebpd,Lif,Psmb10,Rnd1,Icam1,Zfp281,Gbp2,Etv5,Gja1,Dusp6,Pde4b,Slc4a7,Junb,Phlda1,Pdlim7,Ext1,Hk2,Inhba,Dusp5,Arid5b,Rcan1,Nfkb2,Snapc1,Glrx,Igf2bp2,Il15ra,Sod2,Slc7a11,Ccl12,Hivep2,Ets2,Gclm,Edn1,Dusp4,Lrp8,Atf3,Papss2,Il4ra,Ccl22,Plagl1,Tap1,S100a8,Ifit3,Alas1,Isg20,Egln3,Rnf19a,Ell2,Casp7,Dram1,Map2k4,Ifit3b,Irf1,Nfil3 |
| 5.395e-24 | -53.58 | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_UP | 171 | 60 | 15632 | 1249 |
Socs3,Ell2,C3,Ebi3,Lyn,Tlr2,Tnip3,Acvr1b,Ccl4,Tnip1,Trem1,Dcun1d3,P2ry2,Pid1,Ampd3,Pstpip2,Procr,Met,Nfkbiz,Trim13,Fpr2,Spred1,Sod2,Pik3r5,Slc7a11,Ccl12,Ldha,Zc3h12a,Traf3ip2,Clec5a,Irak2,Nfkb2,Cxcl1,Il1b,Plaur,Gch1,Txn1,Samsn1,Cd274,Pdlim7,Ddit4,Cxcl2,AA467197,Plk3,Marcksl1,Traf1,Il1a,Icam1,Hck,Tnfaip3,N4bp1,Tnf,Bcl6,Itgb8,Pnp2,Fut8,Gpr84,Psma6,Gpr68,Errfi1 |
| 8.136e-24 | -53.17 | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_UP | 183 | 62 | 15632 | 1249 |
G3bp2,Rnaset2a,Lad1,Pdgfrb,Slc29a3,Sec24b,Atp10a,Tlr3,Parp3,Fndc3a,Oas1g,Dnaja2,Slamf8,Tapbpl,Cdc42ep4,Stat3,1110038F14Rik,Hdac1,Aebp2,Plekhf2,Psmb9,Crim1,Ch25h,Mcm10,Mthfr,Upp1,Ifih1,Htra1,Psme2,Oas1a,Pdk3,Rabgef1,Ankib1,Rnf14,Irf8,Polr2g,Arf4,Rnaset2b,Vrk2,Wdr43,Endod1,Mtmr14,Lpar1,Irf1,Pdzd11,Asb13,Irf4,Ctsc,Katna1,Gadd45b,Itgav,Spic,Tiparp,Dnaja1,F10,Il15,Rnd3,Rras2,Gng11,Tlr6,Cyth3,Tpx2 |
| 9.020e-24 | -53.06 | regulation of cellular biosynthetic process | biological process | GO:0031326 | 3511 | 383 | 20694 | 1406 |
Stat1,Bcor,Prdx5,Nlrc4,Hat1,Maff,Cd200,Ripk3,Trib1,Pou2f2,Mndal,Mafg,Ptafr,Pdgfb,Klrk1,Ak4,Batf2,Egr3,Stat3,Hck,Src,Hcls1,Tfec,Csrnp1,Birc2,Klf2,Aff1,Plagl2,Dcp1a,Myc,Htr2a,Zeb1,Cenpj,Mecp2,Ell2,Hopx,Spic,Slc9a1,Pf4,Tlr9,Maml2,Ezr,Gja1,Ikbkg,Ccnd1,Nr4a3,Psmd10,Zmynd15,Crlf3,Pcx,Relb,Mdm2,Tal2,Hmga2,Pttg1,Fubp1,Mapkapk2,Hif1a,Il6,Kdm4a,Mamld1,Jag1,Ciita,Cflar,Sap30,Prnp,Fbxo4,Thbs1,Cd34,Prdm9,Rel,Dnajb4,Eno1,Kmt5a,Egr1,Rgcc,Zhx2,Notch2,Ppp1r15a,Bcl6,Gdf15,Txn1,Kdm6b,Egr2,Kdr,Gfpt1,Nlrc5,Cx3cl1,Mdfic,Cacna1d,Mafk,Serp1,Myd88,Met,Zfp281,Arid5a,Gch1,Fcgr2b,Klf8,Pim1,Hmox1,Tlr2,Irak2,Notch1,Pid1,Htra1,Gbp4,Nos2,Ifi208,Parp9,Csf3,Dyrk2,Icosl,Nmi,Tnfsf8,Nfkbie,Ass1,Trim21,Xrn1,Lrp8,Nod2,Nfkbid,Zfp36,Irak3,Hivep3,Ets2,Atp2b4,Ptger4,Mov10,Aim2,Adora2a,Hdac1,Nr4a1,Hinfp,Acvr1,Tnfsf4,Htr2b,Lmo4,Ptch1,Helz2,Ahr,Ifi209,Tnip1,Slc7a11,Ncoa7,Klf3,Arf4,Hhex,Trim13,Acsl5,Irf8,Atm,Ahrr,Fos,Cdyl,Fam129a,Cd38,Timeless,Phip,Tshz1,Ankrd17,Larp1,Igf1r,Psip1,Trim14,Ccl5,Jdp2,Nod1,Ifnb1,Malt1,Junb,Rnf31,Tlr1,Fabp3,C3,Cd74,Stat4,Syk,Ccl3,Ifi204,Sod2,Fzd1,Prdm1,Ago3,Pim2,Brwd3,Pml,Tlr6,Jak2,Errfi1,Cdyl2,Sphk1,Tcea1,Ddx58,Traf5,Hmgn3,Inhba,Irf7,Tnfaip3,Tnfrsf1b,Rnf139,Sp140,Plac8,Ifi211,Nlrp3,Rgs14,Lif,Psma6,Wdr43,Peli1,Nr3c1,Eif4g2,Pdk3,Map2k1,Fpr2,Stat2,Rhoq,Spen,Ifrd1,Nupr1,Il15,Pdgfrb,Cebpd,Fzd5,Ptpn2,Fosb,Kdm5b,Etv6,Nr1h3,Tle3,Rbpms,Plekhn1,Arid4a,Eif2ak2,Plagl1,Slfn1,Aebp2,Stat5a,Batf,Med21,Nfkbia,Adrb2,Gtpbp2,Dcp2,Mllt6,Ifnar1,Ifi205,Tlr3,Keap1,Cdk5r1,Nfkb1,Acp5,Btg2,Rfx5,Il1b,Trib3,Tet2,Polr2g,Perm1,Acvr1b,Dusp1,Nfkb2,Tnfrsf8,Nmral1,Plek,Lhx2,Cpeb4,Bmp2,Zbtb5,Brd2,Ednrb,Ifi214,Agrn,Cacybp,Acvrl1,Nck1,Pla2g4a,Etv5,Ifi207,Phf6,Cdkn1a,Rbbp8,Zfp513,Nampt,Foxp4,Nfkbib,Zc3h12a,Il18,Ythdf1,Gfi1,Traf2,Rnf14,Ripk2,Hlx,Znfx1,Hivep2,Trim26,Nfkbil1,Smg7,Ldlr,Il18rap,Ccne1,Ifi203,Jarid2,Edn1,Resf1,Nsd3,Hmga1,Irf4,Dtx3l,Sav1,Med13,Hspa1a,Cmklr1,Plpp3,Tspo,Klhl25,Irf1,Ppp1r15b,Irf2,Map2k4,Cx3cr1,Dach1,Il10,Acod1,Riox2,Sqstm1,Pbx1,Klf7,Cav1,Osm,Etv3,Sirt1,Casz1,Cyfip1,Nfil3,Klf6,Ptgs2,Ifi213,Bcl9,Ier2,Traf1,Dusp5,Plscr1,Tax1bp1,Hsph1,Rapgef2,Spn,Mier3,Rap2c,Nfxl1,Adora2b,Igf2bp2,Dr1,Mtdh,Mycl,Cd40,Rbl1,Icam1,Jmjd6,Irs2,Kat2b,Max,Arid5b,Gclc,Parp3,Pou3f1,Bambi,Cited2,Plk3,Tnf,Il1a,Daxx,Jun,Tcf4,Pcgf5,Ikzf1,Mxd1,Il27,Parp10,Sertad3,Taf4b,Atf3 |
| 9.127e-24 | -53.05 | positive regulation of cell activation | biological process | GO:0050867 | 327 | 79 | 20694 | 1406 |
Stat5a,Socs1,Ap3b1,Pdpn,H2-Aa,Syk,Bst1,Stxbp1,Il10,Cdkn1a,Tnfsf4,Rasgrp1,Prdm1,Tlr9,Nck1,Ikzf1,Ccl2,Irf1,Myd88,Nfkbid,Irs2,Nod2,Il15,Ccl5,Cd40,Fgr,Vcam1,Stap1,Mmp14,Cd74,Ccdc88b,Nectin2,Il12b,Bcl6,Malt1,Pdgfrb,Il2rg,Hlx,Ripk2,Pdgfb,Cd80,Klrk1,Il6,Ptafr,Adora2b,Cd86,Ptprj,Ctsc,Spn,Hsph1,Thbs1,Cd38,Icosl,Plek,Tnfsf9,Egr3,Peli1,H2-Ab1,Il12rb1,Il4ra,Cav1,Tnfrsf14,Clec4d,Nr4a3,Clcf1,Tnfsf14,Nfkbiz,Tlr6,Jak2,Axl,Il15ra,Lgals9,Nlrp3,Cd83,Cd274,Pik3r6,Il1b,Il18,Itgal |
| 9.254e-24 | -53.04 | GO_NEGATIVE_REGULATION_OF_VIRAL_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_VIRAL_PROCESS | 82 | 41 | 15632 | 1249 |
Jun,Oas3,Ifi205,Ifi209,Ifi213,Eif2ak2,Tnf,Ifit1bl1,Hdac1,Ifnb1,Rsad2,Trim13,Trim12c,Isg15,Ifi214,Parp10,Pml,Ifi207,Zc3hav1,Adar,Mndal,Ifit1bl2,Ccl5,Oas1a,Ifi203,Ifi211,Isg20,Trim14,Trim21,Trim26,Slpi,Ifi208,Plscr1,Ifi204,Fam111a,Zc3h12a,Stat1,Oas1g,Oasl1,Ccl4,Tnip1 |
| 9.350e-24 | -53.03 | WINTER_HYPOXIA_METAGENE | MSigDB lists | WINTER_HYPOXIA_METAGENE | 223 | 69 | 15632 | 1249 |
Hif1a,Icam1,Tnfaip3,Slc2a1,Birc2,Eno1,P4ha2,Hsph1,Ccng2,Errfi1,Hdac1,Pnp2,Cp,Sat1,Nr3c1,Lox,Pim1,Tgfbi,Ptgs2,Adora2b,Ldha,Hmox1,H2-Ab1,Glrx,Pgk1,Plaur,Vegfc,Serpinb2,Thbs1,Nfkb2,Serpine1,Txn1,Hap1,Hk2,Mmp13,Pdgfb,Ddit4,Gbe1,Tpi1,Egr1,Slc16a1,Plau,Pfkfb3,Herc3,Cited2,Jun,Fos,Flt1,Nr4a1,Il6,Edn1,Abcb1a,Bnip3,Odc1,Pim2,Ell2,Itga5,Cdkn1a,Nfil3,Pfkl,Kdr,Dr1,Nos2,Plod2,P4ha1,Nfkb1,Hk1,Pdk3,Met |
| 1.135e-23 | -52.83 | GSE17721_LPS_VS_PAM3CSK4_16H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_16H_BMDC_UP | 184 | 62 | 15632 | 1249 |
Plat,Clic4,Il15ra,Glrx,Keap1,Larp1,Ripk2,Fndc3a,Pim1,Tgfbi,Phyh,Adora2b,Mcm6,Il12b,Il2rg,Il18,Trim26,Inhba,Snx10,Csrp1,Cd274,Tap2,Atp6v1d,Gbp2,F11r,Slco3a1,Isg15,1110038F14Rik,Casp3,Dbnl,Glipr2,Ifnar1,Plod3,Itpr1,Rgs14,Arid5a,Hspa1a,Cflar,Arf4,Kpna3,Tnfsf4,Aida,Acsl1,Atxn7l1,Ppp4r2,Nfkbib,Etv6,Ankib1,Gem,Hdc,Pfkfb3,Sgcb,Rbm43,Cd80,Spred1,Evl,Pttg1,Fcgr2b,Katna1,Cept1,Agrn,Hmga1 |
| 1.136e-23 | -52.83 | DAUER_STAT3_TARGETS_DN | MSigDB lists | DAUER_STAT3_TARGETS_DN | 43 | 30 | 15632 | 1249 |
Hspa1a,Oas3,Ifit1bl1,Eif2ak2,Ifi44,Usp18,Ddx58,Isg15,Ifih1,Trim12c,Ddx60,Ifit3,Lap3,Irf7,Ifit1bl2,Oas1a,Parp12,Tdrd7,Oas2,Trim14,Dnajb4,Ifit3b,Herc6,Ifi35,Tlr3,Oas1g,Oasl1,Stat1,Sp110,Tnfsf10 |
| 1.250e-23 | -52.74 | BILD_HRAS_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_HRAS_ONCOGENIC_SIGNATURE | 224 | 69 | 15632 | 1249 |
Gtpbp2,Cxcl1,Inpp1,Serpinb2,Plaur,Il1b,Cd55,Kdm6b,Dusp5,Ptgs2,Pim1,Phlda1,Hk2,Cxcl2,Nampt,Junb,Gdf15,Tuba4a,Dusp6,Ppp1r15a,Cd274,Tor1aip1,Myd88,Bmp2,Ier2,Mxd1,Lif,Upp1,Il1a,Arg2,Socs1,B3gnt5,Klf6,Ehd1,Slc25a37,Dusp1,Slc16a3,Casp1,Mtus1,Timp1,Bcl6,Clcf1,Ldlr,Col27a1,Lrrc8c,Sema4c,Odc1,Trib1,Lyn,Pik3cd,Ier3,Adrb2,Slc9a1,Flnb,Zfp36,Casp2,Sdc4,Nfkbiz,Egr1,Lrp8,Prnp,Sdc1,Mmp14,Chst11,Mid1,Phactr4,Dusp4,Flrt3,Fos |
| 1.424e-23 | -52.61 | RUTELLA_RESPONSE_TO_HGF_UP | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_UP | 370 | 92 | 15632 | 1249 |
Fscn1,Gfpt1,Ldlr,Tnip3,Lpar1,Rab20,Mmp9,C3,Alas1,Cep350,Me1,Sdc4,Clec4e,Cd80,Slamf7,Nr1h3,Slc30a1,Optn,Rin2,Gadd45g,Cpd,Gclm,Nat2,Trip10,Sqstm1,Sod2,Il1b,Slc29a3,Phyh,Il18,Nr4a3,St3gal1,Slc31a1,Inhba,Cxcl2,Tbc1d13,Fzd5,Serpine1,Ccr1,Csrp1,Kmo,Cers6,Tpst1,Plod3,Cflar,Gpd2,Ebi3,Stat1,Filip1l,Pla2g7,Jag1,Ccrl2,Akt3,Il10,Birc3,Ltbp2,Prdx1,Ccl22,Dmxl2,Sdc2,Nqo1,Irf4,Ccl2,Tspan3,Dock4,Ccl12,Slc7a11,Cmklr1,Slc43a3,Slamf8,Clec5a,Cxcl10,Dusp5,Hk2,Tlr1,Snx10,Rgl1,Txn1,Crim1,Il1a,Sphk1,St3gal6,Traf1,Ccnd1,Gsr,Tbc1d1,Casp3,Ly75,Rhoq,Rab9,Itpr1,N4bp1 |
| 2.046e-23 | -52.24 | leukocyte activation | biological process | GO:0045321 | 519 | 103 | 20694 | 1406 |
Fas,Il15,Fcgr4,Irf4,Fzd5,Ptpn2,Gadd45g,Ifna2,Ptger4,Azi2,Stat5a,Batf,Irf1,Tlr9,Slamf8,Tnfsf4,H60b,Cx3cr1,Lcp2,Jak2,Tlr6,Ripk3,Clec4d,Tlr2,Clec4e,Gpr18,Tnfaip3,Fgl2,Il18,Swap70,Itgal,Pou2f2,Dnase1l3,Rhoh,Ifna5,Raet1e,Klrk1,Ebi3,Batf2,Ifna4,Ripk2,Stat3,Icosl,H2-Ab1,Il18rap,Stx11,Tnfsf8,Dock10,Ptprj,Casp1,Fpr2,Cd40,Icam1,Ccl5,Egr1,Jmjd6,Ifnb1,Notch2,Psmb10,Treml2,Malt1,Bcl6,Tlr1,Il12b,Cd74,Cd180,Syk,Cx3cl1,Tnf,Rsad2,Jun,Ikzf1,Pilrb1,Prdx1,Ifna6,Milr1,Nck1,Fcgr2b,Rasgrp1,Nampt,Ifnar1,Itgav,Gja1,Tlr3,Nr4a3,Clcf1,Prkce,Ahr,Relb,Lyn,Ifna1,Plcl2,Slc7a2,Hhex,Axl,Il6,Atm,Bcl2a1d,Tnfsf9,Spn,Pik3cd,Cd86,Sema4a |
| 2.079e-23 | -52.23 | GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_UP | MSigDB lists | GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_UP | 197 | 64 | 15632 | 1249 |
Ets2,Dnaja1,Fos,Sqstm1,Gadd45b,Nr4a1,Nfkbia,H2-Q4,Ifrd1,Mmp14,Dusp2,Peli1,Myc,Ccl2,Egr1,Nfkbiz,Clec4e,Il10,Birc3,Kctd12,Stat4,Map2k4,Ier3,Irf1,Socs3,Cdkn1a,Tnfaip2,Tax1bp1,Notch2,Tank,H2-Q6,Txnrd1,Dusp1,Tnf,Ehd1,Stk40,Errfi1,Mdm2,Egr2,Icam1,Il1a,Upp1,Nupr1,Marcksl1,H2-Q7,Ier2,Slc30a4,Relb,Cd14,Cd83,Serpine1,Ppp1r15a,Gja1,Junb,Cxcl2,Phlda1,Btg2,Clec4d,Pim1,Ptgs2,Il1b,Plaur,Cxcl1,Il1rn |
| 2.127e-23 | -52.20 | MCLACHLAN_DENTAL_CARIES_UP | MSigDB lists | MCLACHLAN_DENTAL_CARIES_UP | 220 | 68 | 15632 | 1249 |
Msr1,Plac8,Slc7a11,Ccl12,Sod2,Bcl2a1b,Irf4,Fcgr2b,Ctsc,Il6,Plau,Irf8,S100a8,Birc3,Tnfrsf1b,Pla2g7,Slpi,Trib1,Ms4a6d,Mthfd2,Ier3,Acsl1,Lyn,Pim2,Il13ra1,C3,Mmp9,Socs3,Trem1,Nfil3,Hcls1,Timp1,Sele,Fgl2,Cebpd,Bcl2a1d,Sat1,Icam1,Cd74,Hck,Tnfaip3,Cd14,Sla,Lcp2,Samsn1,Ccr1,Nampt,Plek,Fcgr4,Ccl5,Wars,Inhba,Maff,H2-Aa,Phlda1,Ptgs2,Slamf8,Fpr1,Ptger4,H2-Ab1,Cd55,Plaur,Glrx,Il1b,Bcl2a1a,Vcam1,Il1rn,Serpinb2 |
| 2.163e-23 | -52.19 | positive regulation of cell migration | biological process | GO:0030335 | 536 | 105 | 20694 | 1406 |
Angpt1,Met,Ccr1,Abcc1,Ccl12,Rras2,Ccl4,Kdr,Kitl,Jun,Sod2,P2ry12,P2ry2,Il1a,Cx3cl1,Cd74,Igf1r,Cd40,Fgr,Cxcl14,Irs2,Icam1,Ccl5,Egr1,Spn,Thbs1,Pik3cd,Plk2,Rapgef2,Sema4a,Adora2b,Bmp2,Atm,Hif1a,Itga5,Acvr1b,Syne2,Ptgs2,Mdm2,Mmp9,Sirt1,Pdgfc,Fubp1,Lgals9,Cd274,Il1b,Itgav,Sell,Cav1,Tnfrsf14,Lyn,Nr4a3,Prkce,Myadm,Tnfsf14,Plau,Ccl2,Tnfsf4,Acvr1,Vegfc,Ptger4,Plpp3,Cmklr1,Glipr2,Stat5a,Pdpn,Myc,Itga4,Pdgfrb,Ptk2,Mmp14,Rhoc,Sema4c,Edn1,Pla2g7,Serpine1,Carmil1,Spry2,Col18a1,Dock4,Csf1,Sema3c,Map4k4,Stat3,Gcnt2,Src,Fpr2,Map2k1,Ptprj,Pdgfb,Ptafr,Cxcl10,Flt1,Lpar1,Il18,Swap70,Zc3h12a,Sele,Akt3,Notch1,Crkl,Sphk1,Jak2,Tlr2,Hmox1 |
| 2.188e-23 | -52.18 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN | 186 | 62 | 15632 | 1249 |
Usp18,Socs1,Ifih1,Slco3a1,Isg15,Psme1,Hhex,Mthfr,Pml,Daxx,Ifit1,Tnf,Atp13a1,Rsad2,Tapbp,Sat1,Cish,Cox18,Gng12,Il15ra,Cmpk2,Trafd1,Gtpbp2,Slfn3,Lgals9,Slfn4,Tap2,Irf7,Nampt,Dusp6,Tuba4a,Uba7,Noc4l,Stxbp3,Nmi,Ccnd2,Kat2b,Atf3,Usp25,Tap1,Samhd1,Pnpt1,Adar,Znfx1,Eif2ak2,Cox17,Irf4,Irgm2,Tor1aip2,Nat2,Etnk1,Ifi35,Ppa1,Stat1,Mov10,Ogfr,Nfkb1,Ccrl2,Trim21,Isg20,Timeless,Psme2 |
| 2.586e-23 | -52.01 | GSE2585_CTEC_VS_MTEC_THYMUS_DN | MSigDB lists | GSE2585_CTEC_VS_MTEC_THYMUS_DN | 181 | 61 | 15632 | 1249 |
Cst7,Usp53,Tnf,Axl,Cd40,Rhoq,Lif,Jmjd6,Socs1,Ifih1,Cd14,Gja1,Slc4a7,Jarid2,Slc7a2,Ddit4,Stx11,Nfkbid,Sh3bp4,Rnf19b,Herc6,Serpinb9,Fpr1,Clec5a,Ak4,Chic2,Il1rn,Pilrb1,Osbpl3,Ptges,Glrx,Tcea1,Rcl1,Sod2,Agrn,Mrpl52,Gpr18,Gpr35,Fcgr2b,Mapkapk2,Arrdc4,Dmxl2,Pilrb2,Pilra,Pfkfb3,Ahrr,S100a8,Rel,Rap1gap2,Egln3,Hivep3,Slamf9,Jag1,Dtx2,Ell2,Sema4c,Gpd2,Hcls1,Prkar2b,Pfkl,Fam162a |
| 2.586e-23 | -52.01 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_DN | 181 | 61 | 15632 | 1249 |
Tbc1d13,Dgka,Parp12,Car13,Gbgt1,Ddit4,Trim26,Fosb,Il15ra,Slfn9,Gcnt2,Rsbn1,Map3k8,Cox18,Slc43a3,Parp3,Atp10a,Mdm2,Tlk2,Rab9,Rffl,Stat3,Tbc1d1,Rgs14,Casp1,Spryd7,P4ha2,Prpf38a,Cutc,Gbp3,Rnf135,Sertad3,Upp1,Nfkbil1,Ccrl2,Zfp36,Psme2,Slc9a1,Ankib1,Psat1,Nlgn2,Ap3m2,Plekhn1,Ccl4,Tax1bp1,Lyn,Etnk1,Ap3b1,Dusp2,Slfn8,Tmem184b,Rbl1,Atp11b,Aff1,Chmp4b,Enpp4,Rbm43,Rnd3,Xrn1,Prnp,Nfkbiz |
| 2.645e-23 | -51.99 | MODULE_75 | MSigDB lists | MODULE_75 | 373 | 92 | 15632 | 1249 |
Il4ra,Edn1,Igsf6,Il6,Ccl2,Myc,Nqo1,Cxcl14,Nfkbia,Cx3cr1,H2-Q4,Ifit1bl1,Ccl12,Stat1,Irf1,Tlr2,Oas1a,Cd69,Irf8,Tnfsf14,Cd83,Gbp2,Mxd1,H2-Q7,Mthfr,Lif,Il1a,Fgr,Sell,Isg15,C1ra,Cst7,Psmb9,Timp1,Tnfsf10,Il15ra,Pf4,Ptger4,Cd55,Oas1g,Tgfbi,Cxcl10,Ptafr,Pdgfb,Btg2,Tlr1,Csf3,Adora2a,Nampt,Ifit1bl2,Cd86,Il15,Ahr,Fas,Cdk5r1,Cx3cl1,Ctsc,Ccl4,Cdkn1a,Gsta3,C3,Oasl1,Zeb1,Csf1,Isg20,Sema3c,Gem,Batf,Cd14,Aim2,Stat3,Ifi44,P4ha2,Klf6,Stat5a,H2-Q6,Bcl6,Csf3r,Cxcl1,Il1b,Snn,Hp,Il18,Map3k8,Il2rg,Bst1,Ccr1,Fcgr4,H2-Eb1,Lcp2,Irf7,Osm |
| 2.783e-23 | -51.94 | LINDSTEDT_DENDRITIC_CELL_MATURATION_A | MSigDB lists | LINDSTEDT_DENDRITIC_CELL_MATURATION_A | 57 | 34 | 15632 | 1249 |
Pla2g4a,Tnc,Il6,Nfkbie,Scarf1,Ifit2,Tnf,Ccl12,Slc7a11,Sod2,Txnrd1,Cd40,Malt1,Icam1,Isg15,Slc7a5,Stat4,Inhba,Pla2g7,Plek,Ccl5,Cxcl1,Il1rn,Plat,Ccl4,Plaur,Tfec,Il1b,Ptger4,Rtn1,Stat1,Cxcl10,Il12b,Tlr2 |
| 2.881e-23 | -51.90 | GO_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION | 47 | 31 | 15632 | 1249 |
Zc3hav1,Ifi207,Adar,Ifi214,Isg15,Parp10,Rsad2,Ifnb1,Ifi209,Oas3,Ifi205,Ifit1bl1,Tnf,Ifi213,Eif2ak2,Tnip1,Fam111a,Ifi204,Oas1g,Oasl1,Zc3h12a,Ifi203,Oas1a,Ifi208,Plscr1,Slpi,Isg20,Ifi211,Mndal,Ccl5,Ifit1bl2 |
| 2.919e-23 | -51.89 | GO_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_INTRACELLULAR_SIGNAL_TRANSDUCTION | 1459 | 224 | 15632 | 1249 |
Bcl2l11,Ezr,Rab32,Map3k6,Dock4,Psmd10,Prkce,Edn1,Nod2,Abr,Plagl1,Nkiras1,Htr2a,Cdc42ep2,Angpt1,Tnks1bp1,Birc3,Psmb8,Casp4,Akt3,Ksr1,Casp2,Rasgrp1,Ifi203,Sirt1,Stat4,Stat1,Dyrk2,Azi2,Pik3cd,Clcf1,Socs7,Trem1,Src,Birc2,Cd40,Tank,Itpr1,P2ry12,Rgs14,Cish,Casp3,Psma6,Mdm2,Lif,Rhoh,Malt1,Socs1,Stat2,Rab19,Ddx58,Relb,Mdfic,Rgl1,Plk2,Pdgfb,Ptger4,Ptafr,Fpr1,Itgav,Spsb1,Bnip3,Pikfyve,Cd80,Spred1,Tnfrsf1b,Ednrb,Nos2,Cav1,Mov10,Rel,Tifa,Ifi211,Rictor,Rac3,Tlr9,Dgkh,Map2k4,Asb13,Ifi204,Stat5a,Ifi209,Arhgef3,Stat3,Plk3,Psmb10,Ifih1,Tab2,Sav1,Batf,Apaf1,Pdgfrb,Osm,Map2k1,Irf7,Ddit4,Hmox1,Psmb6,Ripk2,Cdc42ep4,Map3k8,Il18,Adora2b,Kitl,Ikbke,Ralgds,Il1b,Htr2b,Pik3r5,Ccl12,Nfkbia,Rhof,Jun,Cyfip1,Myc,Tlr6,Mapkapk2,Ppm1l,Rras2,Rnd3,Mark2,Rnf31,Tnfsf14,Socs3,Tlr2,Hcls1,Kdr,Prkar2b,Igf1r,Ifnar1,Axl,Dusp1,Ifi213,Ifi205,Psmb9,Rhoq,Dbnl,Carhsp1,Rab9,Bcl2a1d,Pml,Nfkbil1,Psme1,Sphk1,Nod1,Rhoc,Ripk3,Daxx,Map4k4,Cd86,Ifi208,Nmi,Tnfsf15,Btg2,Tyk2,Dgka,G3bp2,Traf3ip2,Dusp5,Larp1,Arl5c,Bcl2a1a,Plcl2,Rapgef5,Bcl2a1b,Sqstm1,Syk,Dusp4,Phactr4,Rin2,Cnot4,Arl4a,Irs2,Ifi214,Mul1,Il15,Ifi207,Nfkb1,Ikbkg,Atm,Cenpj,Mndal,Gem,Casp8,Psme2,Slc9a1,Rhou,Ptk2,Lyn,Rab20,Trib1,Rap2c,Arf4,Jak2,Cdkn1a,Tnf,Bcl6,Traf2,Cycs,Rab21,Dock10,Sele,Tlk2,Nupr1,Rnd1,Cd14,Sgk3,Tnfaip3,Ccl5,Dusp6,Plek,Ppp1r15a,Lcp2,Arl5b,Rab10,Rapgef2,Tlr3,Crkl,Il2rg,Rcan1,Trib3,Nfkb2,Irak2,Vcam1 |
| 3.020e-23 | -51.85 | GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP | 176 | 60 | 15632 | 1249 |
Hmox1,Dusp5,Rnf19b,Serpinb9,Tgfbi,Pim1,Serpinb2,Thbs1,Cxcl1,Sp110,Il1b,Stip1,Junb,Serpine1,Cd86,Ppp1r15a,Lcp2,Slc7a5,Btg2,Icosl,Ddit4,Prdm1,Marcksl1,Traf1,Upp1,Icam1,Cd83,Txnrd1,Slc16a3,Phldb1,Plod3,Tnf,Dusp1,Arid5a,Ifi44,Pnp2,Oasl1,Ifit3b,Ccl4,Rgs1,Rbms1,Cdkn1a,Nfkb1,S100a8,Gem,Gna15,Tnfsf14,Ifit3,Zfp36,Cd69,Usp12,Mapkapk2,Atf3,Zc3hav1,Ezr,Tiparp,Hmga1,Ptpn2,Dusp2,Dusp4 |
| 3.205e-23 | -51.79 | GHANDHI_BYSTANDER_IRRADIATION_UP | MSigDB lists | GHANDHI_BYSTANDER_IRRADIATION_UP | 72 | 38 | 15632 | 1249 |
Cd69,Cxcl2,Inhba,Slc39a14,Gch1,Birc3,Nampt,Zc3h12c,Serpinb2,Cxcl1,Bcl2a1a,Ptges,Il1b,Dusp5,Cxcl10,Ptgs2,Osgin2,Dnajb4,Dusp2,Gclm,Sat1,Pla2g4a,Gadd45g,Bcl2a1d,B3gnt5,Gpr68,Bcl2a1b,Slc16a3,Sod2,Slc7a11,Irak3,Relb,Ahr,Tnfaip3,Lif,Nfkbiz,Icam1,Il1a |
| 3.647e-23 | -51.67 | GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | 150 | 55 | 15632 | 1249 |
Slc2a1,Eno1,Arid5a,Slc16a3,Kdm5b,Stat3,Oaf,Jmjd6,Fgr,Hif1a,Cd38,Gys1,Lipg,Sla,Dmwd,Lcp2,Map4k4,Mthfd1l,Hk2,Bst1,Nrp2,Ddit4,Tmeff1,Grina,Tgfbi,Ldha,Snn,Pgk1,Thbs1,Cldnd1,Gramd1a,Pdpn,Pla2g4a,Bnip3,Ctsc,Arrdc4,Pgm1,Ccnd2,Tpi1,Tmem176b,C1rl,Nos2,P4ha1,Ednrb,Eno2,Egln3,Tmem176a,Slc39a14,Sema4a,Socs3,Sema4c,Nfil3,Trem1,Pfkl,Fam162a |
| 3.938e-23 | -51.59 | intracellular membrane-bounded organelle | cellular component | GO:0043231 | 10084 | 863 | 20747 | 1409 |
Tlk2,Ifi35,Calcrl,Mxd1,Gm4841,9930111J21Rik1,Batf2,Vrk2,H2-Q7,Zfp36,Cers6,Serpinb9,Ifi208,Ddit4,Coa5,Ifi203,Pttg1,Uchl1,Themis2,Ell2,Hivep3,Zfp319,Trim21,Parp10,Tap2,Cd86,Cdkn2d,Hcls1,Cenpe,Palld,Plaat3,Rnf114,Dek,Dpy19l1,St3gal6,Edn1,Tent2,Fndc3a,Mt2,Psma6,P2ry2,Ep400,Serpina3g,Ccnd2,Zup1,Mdm2,Gbgt1,Usp12,Atp10a,Rilpl1,Lipe,Nr4a3,Klf7,Tnfaip3,Phlpp1,Cd164,Ranbp2,Stat2,4930453N24Rik,Stat5a,Itpkc,Shfl,Olr1,Spic,Rel,Nfkbib,Hck,Atp11a,Golga3,Hivep2,Ifih1,Cacna1d,Rnf139,Dusp4,Psmd10,Ptk2,Tor1aip1,Pnp2,Polr2g,Nfkb2,Dach1,Rcan1,Adam19,Fgr,Mtdh,Gbp2b,Trip10,Nos2,Usp25,Ero1l,Notch2,Ptger4,Dram1,Ahrr,Hsd17b12,Aldh1b1,Ets2,Rnf145,Cop1,Casp2,Casp7,Kdm5b,Swap70,Pdgfc,Pou2f2,Gm5431,Fos,Tasor2,Lox,Pml,Tspo,Ccdc86,Jun,Cyth3,Zeb1,Etnk1,Cdyl,Uba7,Klf2,P4ha2,Noc4l,Me1,Nmral1,Nr4a1,Rbms1,Shisa3,Kdm6b,Stk40,Dusp1,Phf11b,Parp12,Ikzf1,Phf11a,H2-Ab1,Bfar,Ifnar1,Hsph1,Top3a,Zfp40,Tma16,Igf1r,Tbc1d1,1600014C10Rik,Sap30,Egln3,Txnrd1,H2-Eb1,Egr1,Ier2,Tpx2,Ubr4,Zc3h12a,Jarid2,Parp14,Oas1b,Acsl5,Rab19,Bbx,Ahsa1,Myo10,Tal2,Nfkbid,Alas1,Socs7,Dhrs9,Cdkn1a,Ak4,Sde2,Psip1,Etv3,Cd40,Hhex,Spata13,Pik3r5,Gfi1,Pdgfrb,Atf3,Sbds,Treml4,Psmb10,Irf4,Nampt,Dnajb4,Pcgf5,Hspa1b,Slc39a13,Flnb,Extl2,Mapkapk2,Osbpl3,Aim2,Tpst1,Tra2a,Irf7,Ddx4,Ubash3b,Xaf1,Cited2,Ccne1,Rcn1,Sinhcaf,Ldha,Pbx1,Dnaja2,Slamf7,Rhoc,Itga5,Mppe1,Slc30a1,H3f3b,Oas3,Spire1,Tmtc2,Prdm1,Nfxl1,Arl5c,Slc15a3,Mtfr2,Rab9,H2-Aa,Ikbke,Adap2,Mcmbp,Rfx5,Agpat4,Nck1,Rab10,Ezr,Vezt,Tiparp,Milr1,Rsad2,Irgm1,Nod2,Chd9,Nfkbia,Dock4,Plekhn1,Rab21,Tut7,Kat2b,Mfap3l,Plekhf2,Etv6,Tgs1,Trim13,Pgap2,Slc25a25,Gem,Tap1,Adrb2,Prkx,Abcc1,Slc16a1,Rars,Syk,Flt1,Caml,Zbtb5,Rasgrp1,Crlf3,Mcoln2,Nfkbie,Ptch1,Med21,Nek6,Rnaset2b,Grina,Gpd2,Daxx,Lyn,Isg15,Ap3b1,Stat4,Ext1,Pla2g4a,Phf11d,Hmox1,Stat1,Foxp4,Whamm,Isg20,Anp32a,Rsbn1,Plekha2,Irgm2,Ncoa5,Dusp16,Arl4a,Btg2,Tapbp,Kcnj2,Bcl6,Mitd1,Fzd5,Cacybp,Hat1,Vcam1,Oas1g,Ehd1,Ifi213,St3gal1,Tor3a,Perm1,Psme1,Dock10,Gsap,Socs1,Dcp2,Tle3,Nt5c3,Phlda1,Ppp1r15a,Casp3,Oas2,Vcpip1,Rhbdf2,Wars,Plod2,Marf1,Grk3,Rhou,Cdyl2,Junb,Fignl2,Klf8,Ifi214,Mdn1,Fam111a,Flrt3,Cx3cr1,Psmb6,Mthfd2,Plekha5,Slc16a3,Cd14,Jmjd6,Mark2,Noct,Stap1,Zfp800,Sh3bgrl2,Ifit3,Pde4b,Arf4,Trim14,Fam20c,Chic2,Rab11fip1,Kmt5a,Gk,Samsn1,Znrf1,Acod1,Hmgn3,Rgcc,Ifi204,Slc29a3,Bcorl1,Ccl2,Hsd17b7,Mx2,Crbn,Map2k4,P2ry13,Ccnj,Prpf4,Pdk3,Ier3,Slfn5,Ifit3b,Asah2,Asap3,Dmwd,Maff,Nr3c1,Nfkbiz,Traf2,F10,Hdac1,Slc25a12,Tyk2,9130023H24Rik,Rnd3,Pgs1,Mecp2,Ifi209,Rgs3,Ociad1,Cycs,Snx10,Lacc1,Phyh,Plod3,Ifi207,Usb1,Ciapin1,Rnf14,Gadd45g,Rab32,Lipg,Myc,Mtcp1,Mov10,Tnks1bp1,Arid5a,Gadd45b,Il15ra,Sema4a,Thbs1,Nfil3,Clic5,Mapkbp1,Iigp1,Tmem67,Acp5,Ifi211,Ifrd1,Pdlim7,Sqstm1,Ahr,Parp9,Gbp2,Tcea1,Setdb2,Plscr1,Tlr6,Slc49a4,Rpgrip1l,Notch1,Slc7a11,Phip,Serpinb6b,Glrx,H2-Q6,Akt3,Stxbp1,Cpeb4,Dusp14,Pdss1,Rnf24,Gcnt2,Med13,Hspa1a,Pkp4,Oasl1,Hilpda,Smox,Pigv,Dennd1b,Ass1,Lpcat2,Slc30a4,Hif1a,Mthfd1l,4932438A13Rik,Stard7,Slc48a1,Ppp1r15b,Cox18,Nfkbil1,Ascc3,Ccnd1,Sertad3,Relb,Helz2,Armc8,Ifi205,Rnaset2a,Riox2,Zbp1,Mcm10,Sav1,Acpp,Tshz1,Acsl1,Fut8,Triobp,Gtpbp2,Nlrc5,Zmynd15,Pmepa1,Gmppb,Pim1,Kmo,Tgfbi,Rhof,N4bp1,Arid4a,Lrrc8c,Mmp13,Rgs14,Sphk1,Chst11,Marcks,Slc25a22,Prdm9,Hinfp,Tlr2,Malt1,Mamld1,Htr2b,Sec24a,Apobec3,Atp11b,Usp18,Rtn1,Mgat1,Nfkb1,Usp31,Nupr1,Igtp,Hp,Tnip1,Dnajb2,Ptgs2,Slc9a1,Tor1aip2,Mcm6,Aebp2,Cd34,Birc3,Slc2a1,Max,Ednrb,Acp2,Srgn,Rbl1,Magohb,Ptges,Yju2,Gm12185,Bcl2a1b,Clcn7,Agtrap,Cxcl14,Mvp,Stx11,Resf1,Dse,Sh3bp4,Batf,Arl5b,Snn,Mafk,Cpd,Vasn,Bcor,Ccdc88b,Ripk3,Wdr59,Arg2,Rab20,Irf1,Oasl2,Lgals9,Ankrd17,Psmb9,Ldlr,Snapc1,Brwd3,Ch25h,Stip1,AA467197,Sp100,Ctsc,Etv5,Ctu1,Mx1,Plagl2,Tab2,Mycl,Casp4,Gch1,Rrs1,Rnd1,Hspa2,Gbp3,Sp110,Tnfrsf1b,Egr2,Prkce,Jak2,Rrbp1,Znfx1,Fam72a,Ciita,Dtx3l,Trim12c,Nxf1,Rubcnl,P4ha1,Scyl2,Cox17,Rnf19b,Slc37a3,Sik3,Map2k1,Zfp281,Casp1,Fam162a,Fosb,Aff1,Glipr2,Zc3hav1,Apaf1,Kpna3,Mcm9,Rmdn3,Tgtp1,Optn,Tapbpl,Bcl2a1d,Samhd1,Cenpj,Hap1,Irf2,Psmb8,Cept1,Jdp2,Nsd3,Fubp1,Rab3ip,Ube2e1,Adhfe1,Plk3,B3gnt5,Ccng2,Snx2,Parp3,Dusp5,Klf6,Brd2,Phlpp2,Trib1,Fabp7,Arid5b,Nmi,Tgtp2,Tfec,Gsdmd,Il4i1,Klf3,Fas,Rai14,Rap1gap2,Idi1,H2-Q4,Plac8,Cd74,Dusp8,Zfp513,Kdm4a,Tmem176b,Cst7,Tmem178,Cgas,Gja1,Hmga2,Lap3,Pou3f1,Gm4951,Pfkfb3,Pnpt1,Fam241a,Sgms2,Ksr1,Plekhg1,Trmt1l,Actb,Mdfic,Mrpl52,Casp8,Psme2,Bcl9,Irak2,Ktn1,Car13,Tlr1,Plk2,Plpp3,Rbms2,Tlr9,St3gal3,Ust,Hmga1,Prnp,Eif2ak2,Pmaip1,Mmd,Atp13a1,Lnpk,Ppm1k,Gpr85,Slc44a1,Rbbp8,Ago3,Csrp1,Cav1,Stat3,Dck,Hk1,Uaca,Prpf38a,Tent4a,Spen,Plagl1,Rbpms,Tdrd7,Katna1,Wdfy1,Mier3,Sesn3,Lhx2,Ralgds,Cnot4,Mmp14,Herc6,Spred1,Hk2,Trim30a,Apba1,Stx6,Adar,Prdx5,Flrt2,Mt1,Timeless,Gpc1,Tomm70a,Dbnl,Carmil1,Clcn5,Rabgef1,Kdr,Ncoa7,P2ry12,Bcl2l11,Zhx2,Morc3,Birc2,Oas1a,Smc5,Minpp1,Naa25,Hopx,Slfn9,Ap3m2,Sod2,Dusp2,Serp1,Slc7a5,Trib3,Cnp,Dnase1l3,Chmp4b,Wdr43,Armcx6,Mpp7,Slfn1,Cdk5r1,Spry2,Slc25a37,Csrnp1,F830016B08Rik,Dr1,Ptpn2,Degs2,Filip1l,Rcl1,Dnaja1,Bnip3,Nlrp3,Sirt1,Syne2,Rapgef5,Il15,Ifi47,Clic4,Rtn2,Upp1,Parp11,Tcf4,Dcp1a,Myo1b,Dync1h1,Dyrk2,Spn,St3gal5,Keap1,Src,Gsr,Tlr3,Eya4,Dtx2,Vps54,B4galt4,Atm,Prdx1,Mtus1,Asf1a,Gdf15,Ikbkg,Irf8,Mefv,Phf11c,Abtb2,Maml2,Tulp3,Itgav,Phf6,Pcx,Errfi1,Tet2,Smg7,Stau1,Trip13,Il1b,Mafg,Casz1,Sco1,Pde3b,Ifit2,Mul1,Cutc,Aftph,Ric1,Ppp2r5a,Irak3,Trim26,Zfp945,Nr1h3,Bcl2a1a,Peli1,Ppp4r2,Egr3,Ift57,Cep350,Dst,Hk3,Rnf34,Crkl,Hlx,Cd38,Ogfr,Zyx,Prag1,Higd1a,Txn1,Sp140,Mndal,Cmpk2,Cebpd,Gramd1a,Igf2bp2,Taf4b,Piezo1,Myd88,Itpr1,Mosmo,Fam53c,Bmp2,Eef1e1 |
| 4.019e-23 | -51.57 | WONG_ADULT_TISSUE_STEM_MODULE | MSigDB lists | WONG_ADULT_TISSUE_STEM_MODULE | 662 | 131 | 15632 | 1249 |
Atf3,Nfkbiz,Nfkbia,Ifit1bl1,Tagln,Fos,Jun,Prkce,Il6,Rai14,Cxcl14,Ebi3,Etnk1,Cd200,Socs3,Ell2,Adrb2,Ier3,Ltbp2,Casp4,Procr,Htra1,Flnb,Ampd3,Stat4,Ube2e2,Marcksl1,Hlx,Ier2,Icam1,Traf1,Slco3a1,Isg15,Crim1,Mdfic,Relb,Dusp1,Lrp4,Hspa1a,Cd40,Cish,Dusp8,Rhoq,Ly75,Egr2,Ccnd1,Cebpd,C1ra,Ptger4,Ptgs2,Thbs1,Clic4,Sec24b,Hcar2,Txn1,Junb,Snx10,Ifit1bl2,Gch1,Myo1b,Klf2,Asah2,Plk2,Btg2,Rilpl1,Scn1b,Phlda1,Dgka,Tmem176b,Evl,Col18a1,Stxbp1,Sdc1,P2ry14,Il15,Cd34,Trp53i11,Col4a2,Nr4a1,Cnn2,Mrpl52,Spic,Cited2,Ets2,Dusp2,Phlpp1,Dusp4,Gadd45g,Dnajb4,Rab20,Ppfibp2,Cdkn1a,Dnajb2,Frmd6,Abcc1,Pmepa1,Ahrr,Cav1,Gem,Sik3,Cnn3,Tmem176a,Rhou,Mcoln2,Nupr1,Ifih1,Pbx1,Klf6,Plekha5,Tpst1,Tcf4,Tnc,Ifi44,Errfi1,Rbpms,Hspa2,Trib3,Il18,Vcam1,Cxcl1,Kitl,Il1b,Plek,Myadm,Ccl5,Gja1,Ppp1r15a,Irf7,Serpine1,Fosb,Ddit4 |
| 4.057e-23 | -51.56 | BASSO_CD40_SIGNALING_UP | MSigDB lists | BASSO_CD40_SIGNALING_UP | 93 | 43 | 15632 | 1249 |
Cflar,Ccl4,Tnfaip2,Rgs1,Pik3cd,Lyn,Ier3,Ell2,Stat1,Dtx2,Irf4,Dusp2,Trip10,Nfkbia,Gadd45b,Bcl2a1b,Tap1,Ccl22,Mapkapk2,Icosl,Ddit4,H2-Aa,Plek,Junb,Snn,Il1b,Bcl2a1a,Nfkb2,Arid5b,Map3k8,H2-Ab1,Nfkbie,Bcl2a1d,Cd40,Stat5a,Ehd1,Tnf,Tnfaip3,Cd83,Batf,Cd74,Icam1,Traf1 |
| 4.738e-23 | -51.40 | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP | MSigDB lists | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP | 194 | 63 | 15632 | 1249 |
Trafd1,Sp110,Cmpk2,Slfn3,Cxcl10,Osgin2,Parp3,Tlr3,Uba7,Parp12,Oas2,Pdgfrb,Irf7,Tap2,Slfn4,Tor1aip1,Ifit1bl2,Psmb10,Ifih1,Isg15,Socs1,Usp18,Irf2,Rsad2,Ly75,Ifi44,Cp,Ifit2,Pmepa1,Actb,Tlr2,Ifit3b,Irf1,Stat1,C3,Ifi35,Casp7,Kctd12,Mmd,Trim21,Csf1,Gbp7,Ifit3,Tor3a,Angpt1,Samhd1,Adar,Rbm43,Zbp1,Rtp4,Cdk5r1,Usp25,Fas,Nck1,Ddx60,Parp9,Rin2,Parp14,Irgm2,Sod2,Ccl12,Ifit1bl1,Eif2ak2 |
| 4.815e-23 | -51.39 | GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 1309 | 207 | 15632 | 1249 |
Ednrb,Cav1,Nos2,Spen,Ifi211,Zeb1,Tlr9,Mtdh,Egr3,Mmp9,C3,Ifi204,Lpar1,Gsdmd,Cited2,Pla2g4a,Mmp14,Scarf1,Kat2b,Cx3cl1,Il27,Cd34,Cd80,Clec4e,Gpc1,Tspo,Enpp4,Zc3hav1,Ccr1,Gja1,Fzd5,Cd274,Serpine1,Map2k1,Pdgfrb,Irf7,Mmp13,Hmox1,Ripk2,Adora2b,Il18,Nr4a3,Kitl,Gcnt2,Il1b,Htr2b,Stat5a,Phldb1,Ifi209,Tcf4,Mecp2,Glipr2,Prdx5,Aim2,Prdm1,Ifih1,Rnf135,Myd88,Ccdc88b,Cd38,Irak3,Irf8,Ptch1,Cysltr2,Jag1,Sirt1,Met,Ifi203,Rasgrp1,Nox1,Adrb2,Clcf1,Nlgn2,Ezr,Flt1,Agrn,Flrt3,Fos,Edn1,Irf4,Prkce,Nod2,Egr1,Nlrp3,Htr2a,Zbp1,Tnfrsf14,Angpt1,Pdgfb,Csf3,Ptger4,Zc3h12a,Ptafr,Thbs1,Bambi,Vegfc,Pf4,Src,Rgs14,Cd40,Hspa1a,Pnp2,Ccnd1,Kdm5b,Hlx,Malt1,Lif,Il1a,Ddx58,Hif1a,Isg15,Cd83,Tnfrsf8,Notch1,Nfkb1,Mndal,Casp8,Slc9a1,Csf1,Mmd,Itga5,Trib1,Lyn,Jak2,Spn,Eif2ak2,Syk,Ap3b1,Pde5a,Ifi214,Mul1,Il15,Ifi207,Pde4b,Plek,Ccl5,Flrt2,Nrp2,Pdlim7,Il12rb1,Inhba,Rapgef2,Tlr3,Nfkb2,Tnf,Traf2,H2-Q6,Serp1,Bcl6,Rab21,Dhx58,Rsad2,Gpr68,Cd74,Cd14,Lipg,Etv5,Tnfaip3,Clec4n,Il10,P2ry2,Ebi3,Tnfsf4,Acvr1b,Irf1,Tlr2,Hcls1,Kdr,Fam20c,H2-Q4,Cx3cr1,Ccl12,Jun,Ccr3,Il6,Myc,Peli1,Lrp8,Mapkapk2,Tlr6,Il4ra,Plau,Mark2,Cd86,Pik3r6,Ifi208,Scn1b,Tlr1,Hap1,Ptgs2,Clec5a,Il12b,Hcar2,Axl,Ifi213,Ifnar1,Casp1,Ifi205,Acvr1,Acvrl1,H2-Q7,Pml,Icam1,Sphk1,Fgr,Nod1,Bmp2 |
| 4.895e-23 | -51.37 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN | 156 | 56 | 15632 | 1249 |
Sp140,Psmb9,Casp3,Sell,Gbp3,Ifih1,Isg15,Psmb10,Dtx3l,Cd38,Gch1,Pde4b,Cd274,Tlr1,Ube2l6,Maff,Stx11,Rapgef2,Ptger4,Arid5b,Tnfsf10,Lrp11,Epsti1,Lacc1,Hivep2,Cyfip1,Peli1,Slc44a1,Parp14,Samd9l,Dusp4,Parp9,Gadd45g,Chst11,Xrn1,Kat2b,Rras2,Tap1,Ccne1,Birc3,Lmo4,Plekhg1,Irf8,Atxn7l1,Tifa,Ksr1,Etv6,Rhou,Sirt1,Cd200,Stat1,Ebi3,Ifi35,Parp11,Frmd6,Dusp16 |
| 5.083e-23 | -51.33 | regulation of DNA-binding transcription factor activity | biological process | GO:0051090 | 396 | 87 | 20694 | 1406 |
Nlrp3,Gfi1,Il18,Zc3h12a,Irak2,Hmox1,Tlr2,Traf5,Hmgn3,Ripk3,Cd200,Pim1,Ddx58,Tnfaip3,Trib1,Nlrc4,Tlr6,Jak2,Sphk1,Nfkbib,Il18rap,Hcls1,Hck,Stat3,Csf3,Peli1,Trim26,Nfkbil1,Psma6,Ripk2,Traf2,Med13,Sav1,Irak3,Lrp8,Nupr1,Nfkbid,Nod2,Edn1,Trim21,Ifrd1,Tnfsf4,Il10,Cx3cr1,Tlr9,Nfkbia,Eif2ak2,Aim2,Cmklr1,Plpp3,Hmga2,Il1b,Trim13,Sirt1,Psmd10,Keap1,Pbx1,Cav1,Ikbkg,Ptch1,Acod1,Tlr3,Prnp,Tax1bp1,Tnfrsf8,Traf1,Cflar,Il6,Malt1,Arid5b,Rnf31,Icam1,Rgcc,Trim14,Nod1,Cd40,Igf1r,Mtdh,Parp10,Fcgr2b,Myd88,Tnf,Cx3cl1,Fzd1,Cacna1d,Syk,Nlrc5 |
| 5.173e-23 | -51.32 | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | MSigDB lists | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | 229 | 69 | 15632 | 1249 |
Lox,Rnf19b,Cd55,Ripk2,Il15ra,Plaur,Il1b,Glrx,Gtpbp2,Bcl2a1a,Snapc1,Klf2,Irf7,Junb,Pde4b,Gch1,Csf3,Wars,Cxcl2,Tmeff1,Nmi,Phlda1,Il1a,Hif1a,Tab2,Upp1,Irf2,Ier2,Myd88,Mtus1,Timp1,Parp8,Dusp1,C1ra,Bcl2a1d,Sat1,Stat3,Fut8,Pnp2,Carhsp1,Ifi35,Sema4c,Socs3,Vrk2,Casp4,Rnf31,P4ha1,Procr,Isg20,Alas1,Plscr1,Pikfyve,Dtwd1,Pgs1,Evl,Tap1,Olr1,Plau,Rnd3,Ets2,Ptpn2,Dock4,Gsdmd,Sod2,Bcl2a1b,Ifrd1,Bnip3,Il6,Peli1 |
| 5.636e-23 | -51.23 | GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | 146 | 54 | 15632 | 1249 |
Gypc,Ankrd17,Minpp1,Ly75,Cdyl2,Dhx58,Mxd1,Magohb,Pml,Klf8,Crlf3,Gnb4,Nod1,Cd38,Crim1,Brwd3,Pik3r6,Nfkbid,Il12rb1,Wars,Hap1,Tbc1d13,Arl5c,Phyh,Ttc39b,Prkx,Dcbld2,Fmnl2,Slc37a3,Ppp2r2a,Sec24b,Cmpk2,Nlrc5,Ikzf1,Peli1,Cox17,Il18bp,Plagl1,Pttg1,Arl4a,Htr2a,Tnks1bp1,Angpt1,Casp8,Ptch1,Cysltr2,Rasgrp1,Il18rap,Uaca,Lpar1,Zcchc2,Whamm,Lhx2,Socs7 |
| 5.746e-23 | -51.21 | GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_UP | MSigDB lists | GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_UP | 189 | 62 | 15632 | 1249 |
Irs2,Rtp4,Ahr,Adar,Znfx1,Tmem184b,Fam43a,Rnf114,Phlpp1,Stap1,Ifit3b,Ifi35,Egr3,Stat1,Dck,Pmepa1,Cd300lf,Rgs1,Ifit3,Rel,Rnf14,Ccrl2,Oas1a,Xaf1,Isg20,St3gal5,Usp18,Ddx58,Hif1a,Marcksl1,Ifit1,Gpsm2,Ifit2,Zfp800,Lztfl1,Mafk,Rsad2,Dhx58,Rhoq,Pde1b,Ifi44,Frmd4a,Ptger4,Oas1g,Cmpk2,Sp110,Osbpl3,Gtpbp2,Irak2,Sec24a,Cd86,Plk2,Samsn1,Lgals9,Myo1b,Atp6v1d,Irf7,Nampt,Car13,Parp12,Ube2l6,H2-Aa |
| 5.858e-23 | -51.19 | Influenza A | KEGG pathways | mmu05164 | 168 | 61 | 7931 | 713 |
Akt3,Jun,Tyk2,Nfkb1,Hspa1b,Stat1,Oas2,Oas3,Nfkbib,Casp1,Ifnar1,Ifna5,Actb,H2-Aa,Pml,Nlrp3,Nxf1,Rsad2,Ccl2,Adar,Ccl5,Oas1b,H2-Eb1,Icam1,Ciita,Il6,Stat2,Ifna4,Il1a,Map2k1,Socs3,Ccl12,Tnfsf10,Ifna1,Ddx58,Ifih1,Oas1g,Ifna2,Cxcl10,Tnf,Irf7,Fas,Nfkbia,Tlr3,Pik3cd,Ikbke,Map2k4,Cycs,Il18,Ifnb1,Il12b,Il1b,Hspa2,Oas1a,Myd88,H2-Ab1,Hspa1a,Jak2,Mx2,Eif2ak2,Ifna6 |
| 5.858e-23 | -51.19 | Influenza A | KEGG pathways | ko05164 | 168 | 61 | 7931 | 713 |
Akt3,Nfkb1,Jun,Tyk2,Stat1,Hspa1b,Ifnar1,Casp1,Nfkbib,Oas3,Oas2,Actb,Ifna5,Pml,H2-Aa,Nlrp3,Rsad2,Ccl2,Nxf1,Ccl5,Adar,Oas1b,Icam1,H2-Eb1,Il1a,Ifna4,Stat2,Il6,Ciita,Socs3,Ccl12,Map2k1,Ddx58,Ifna1,Tnfsf10,Oas1g,Ifih1,Ifna2,Tnf,Cxcl10,Nfkbia,Fas,Irf7,Tlr3,Pik3cd,Ikbke,Cycs,Map2k4,Il18,Ifnb1,Il12b,Il1b,Jak2,Hspa1a,H2-Ab1,Myd88,Oas1a,Hspa2,Eif2ak2,Mx2,Ifna6 |
| 5.891e-23 | -51.19 | GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_UP | MSigDB lists | GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_UP | 178 | 60 | 15632 | 1249 |
Cd83,Crim1,Relb,Tnfaip3,Hck,Lrch3,Marcksl1,Slco3a1,Traf1,Top3a,Nfkbie,Src,Dusp1,Cst7,Tank,Plat,Pf4,H2-Ab1,Clec5a,Il2rg,Btg2,Icosl,H2-Aa,Phlpp2,Pdlim7,Slc2a6,Wars,Dgka,Pde4b,Junb,Sdc4,Gng11,Clec4e,Pde3b,Slamf7,Olr1,Ahr,Atf3,Ccl22,Irf4,Stard5,Aftph,Dusp2,Sdc2,Chst11,Nfkbia,Sod2,Slc7a11,Cflar,Orai2,Tnip1,Tnfsf4,Ptgir,Irf1,Isg20,Akt3,Spen,Etv6,Birc3,Nfkb1 |
| 6.457e-23 | -51.09 | GO_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | MSigDB lists | GO_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 218 | 67 | 15632 | 1249 |
Il10,Rel,Tnfsf14,Casp8,Birc3,Clec4n,Rnf31,Ikbkg,Sirt1,Nfkbib,Lpar1,Tnip3,Tlr2,Mtdh,Tlr9,Pim2,Stat1,Cflar,Tnip1,Psmd10,Nfkbia,Sqstm1,Nod2,Optn,Prkce,Peli1,Trim13,Nlrp3,Mul1,Nek6,Tlr6,Zc3hav1,Angpt1,Prdx1,Plk2,Gja1,Nfkbid,G3bp2,Ptgs2,Il12b,Il18,Tlr3,Ripk2,Zc3h12a,Traf3ip2,Hmox1,Htr2b,Il1b,Tnfsf10,Ikbke,Traf2,Cd40,Birc2,Ankrd17,Tnf,Casp1,Il1a,Tab2,Trim12c,Sphk1,Malt1,Rhoh,Rhoc,Tnfaip3,Myd88,Nod1,Traf5 |
| 6.898e-23 | -51.03 | GSE17721_12H_VS_24H_GARDIQUIMOD_BMDC_UP | MSigDB lists | GSE17721_12H_VS_24H_GARDIQUIMOD_BMDC_UP | 184 | 61 | 15632 | 1249 |
Vrk2,Pmepa1,Ap3m2,Lhx2,Cd300lf,Kdr,Ccl4,Rbms1,Asb13,Aida,Endod1,Ifi35,Met,Jag1,Zfp36,Alas1,Pstpip2,Mov10,Nfkb1,Psat1,Samhd1,Ciita,Aldh1b1,P2ry14,Prnp,Usp25,Evl,Parp9,Il4i1,Sbds,Il1b,Ppp2r2a,Sec24b,Sp110,Il15ra,Plat,Prkx,Pcdh7,Slamf8,Tlr3,Uba7,Caml,Icosl,Irf7,Cd86,Cdyl,Prpf38a,Cd164,Fabp3,Sphk1,Pml,Mcm10,Mdm2,Hdac1,Batf2,Dbnl,Cish,Gpr84,Gpsm2,Cd40,Csf3r |
| 8.193e-23 | -50.86 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_UP | 179 | 60 | 15632 | 1249 |
Timp1,Klf6,Cst7,Rbpms,Bcl2a1d,D1Ertd622e,Ly75,Rhoq,Traf1,Sell,Isg15,Marcksl1,Plk3,Tnfaip3,Traf5,Hopx,Cacybp,Cd86,Irf7,Stx11,Ddit4,Nmi,Kcna3,Rcan1,Ak4,Rnf19b,Dusp5,Ldha,Il15ra,Bcl2a1a,Vcam1,Il1rn,Ets2,Gadd45b,Nfkbia,Morc3,Bcl2a1b,Gadd45g,Irf4,Aldh1b1,Nr1h3,Dmxl2,Nlrp3,Ahr,Olr1,Eno2,P4ha1,Nfkb1,Cnn3,Ier3,Casp7,Cd200,Mmp9,Vrk2,Prkar2b,Ap3m2,Cflar,Fscn1,Adam19,Ccl4 |
| 8.335e-23 | -50.84 | DIRMEIER_LMP1_RESPONSE_EARLY | MSigDB lists | DIRMEIER_LMP1_RESPONSE_EARLY | 62 | 35 | 15632 | 1249 |
Junb,Birc3,Irf7,Ppp1r15a,Zfp36,Btg2,Cd69,Dusp5,Zc3h12a,Egr3,Kdm6b,Hmgcs1,Ccl4,Nfkb2,Bcl2a1a,Actb,Bcl2a1b,Nfkbia,Gadd45b,Klf6,Tnf,Jun,Cd40,Dusp2,Myc,Egr2,Bcl2a1d,Nfkbie,Egr1,Nfkbiz,Ier2,Traf1,Icam1,Cd83,Tnfaip3 |
| 9.516e-23 | -50.71 | GSE17721_PAM3CSK4_VS_CPG_6H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_6H_BMDC_DN | 185 | 61 | 15632 | 1249 |
Car13,Noc4l,Cnp,Rgl1,Il15ra,Stip1,Plat,Slamf8,Rnf19b,Hdac1,Sele,Tlk2,1110038F14Rik,Tnc,Stat3,Dbnl,Rab9,Tank,Apobec3,Plekhf2,Cd164,Sgk3,Sav1,Bfar,Myd88,Rnf34,Cutc,Mcm10,Itga4,Irf2,Rhoh,Etv6,Kctd12,Bcl9,Pdss1,Plekha2,Ankib1,Clcf1,Rap2c,Cd300lf,Asf1a,Odc1,Rcn1,Kpna3,4932438A13Rik,Cept1,Ncoa5,Tra2a,Vcan,Triobp,Klf3,Rnf114,Dusp14,Hinfp,Gng11,Coa5,Phip,Slc30a1,Sass6,Nfkbiz,Tlr6 |
| 1.092e-22 | -50.57 | regulation of cell adhesion | biological process | GO:0030155 | 686 | 121 | 20694 | 1406 |
Il10,Tnfsf4,Adrb2,Adam19,Plau,Irf1,Ccl2,Stat5a,Pdpn,Socs1,Ap3b1,Adora2a,Slfn1,Plpp3,Ptger4,Vegfc,Bst1,Tnc,Ptk2,Mmp14,Rac3,Prkx,Itga4,Myo10,Pde5a,Ptpn2,Carmil1,Serpine1,Nfkbid,Csf1,Il15,Triobp,Ptprj,Map2k1,Ass1,Map4k4,H2-Ab1,Egr3,Peli1,Gcnt2,Icosl,Src,Cyth3,Hlx,Ripk2,Piezo1,Arg2,Ptafr,Nlrp3,Notch1,Zc3h12a,Itgal,Swap70,Fgl2,Il18,Tnfaip3,Il12rb1,Tarm1,Crkl,Jak2,Spint2,Pml,Rasgrp1,Sdc4,Nck1,Acvrl1,Angpt1,Ikzf1,P2ry12,Cx3cl1,Tnf,Plekha2,Syk,Pde3b,Cited2,H2-Aa,Ubash3b,Kdr,Ccdc88b,Cd74,Rnd1,Il12b,Il1rn,Bcl6,Malt1,Ifnb1,Ccl5,Icam1,Rgcc,Vcam1,Cd86,Bmp2,Thbs1,Hsph1,Spn,Prnp,Tnfsf9,Il2rg,Jag1,Atm,Il6,Cd80,Itga5,Dusp1,Lgals9,Il1b,Pik3r6,Cd274,Cd83,Hsd17b12,Tnfrsf14,Cav1,Lyn,Il4ra,Tnfsf14,Myadm,Nr4a3,Prkce,Nfkbiz,Itgav,Casp3 |
| 1.160e-22 | -50.51 | cellular process | biological process | GO:0009987 | 14222 | 1124 | 20694 | 1406 |
Keap1,Ppm1l,Ppp2r5a,Ifi205,Plat,Tlr3,Pim3,Trib3,Polr2g,Gpr141,St3gal5,Lrrc8c,Tnfrsf8,Saa3,Cnn2,Otud1,Mcm9,G3bp2,Acvr1b,Dusp1,Bmp2,Cep350,Casp2,Zbtb5,Tnfsf9,Lhx2,Ube2l6,Mtfr2,Slc7a5,Stxbp3,Brd2,Ogfrl1,Agrn,Traf3ip2,Ccdc88b,Ednrb,Tra2a,Psmb10,Ifi214,Mt2,P2ry2,Arhgap26,Spaca6,Sik3,Pla2g4a,Cp,Etv5,Abcc1,Uba7,Sdc4,Abtb2,Rbbp8,Denr,Casp8,Pikfyve,Nampt,Acvrl1,Slfn5,Rnf19a,Ddx58,Hmgn3,Vasn,Irf7,Tnfaip3,Timp1,Jak2,Errfi1,Rap1gap2,Sphk1,Rab19,Pdss1,Zc3hav1,Akt3,P2ry14,Tnfrsf1b,Rnf139,Itga9,Plac8,Ifi211,Ifi47,Psma6,Dnaja2,Tnfsf15,Oas1a,Usp12,Arg2,Marcks,Lif,Raet1e,Pdk3,Eif4g2,Trim12c,Map2k1,Odc1,Fpr2,Bcl2l11,Sass6,Nr3c1,Csf1,Nupr1,Gsr,Hcar2,Igsf9,Gpr84,Ccng2,Dnajb2,Snapc1,Sipa1l1,Rhoq,Tor1aip1,Spen,Hspa2,Antxr1,Dgkh,Dusp14,Kdm5b,Rac3,Fosb,Etv6,Gda,Ptk2,Fzd5,Ptpn2,Gm12185,Pnpt1,Slfn1,Ppm1k,Aebp2,Apobec3,Tnc,Herc6,Ifit3,Sco1,Psmb8,D1Ertd622e,Ccl2,Batf,Cept1,Stard5,Med21,Arrdc4,Slc30a1,Psmb9,Trim30a,Cxcl11,Myadm,Spire1,Slc31a2,Cav1,St3gal3,Itpr1,Acod1,Samd9l,F11r,Tagln,Etv3,Slc2a1,Sirt1,Ccl22,Ctu1,Arel1,Ptgs2,Ifi213,Mgat1,Gna15,Bcl9,Ifit2,Oasl2,Ier2,Ralgds,Cyfip1,Rap2c,Mrpl52,Marf1,Cd86,Tmem219,Tax1bp1,Rapgef2,Dmxl2,Slc16a1,Jmjd6,Dync1h1,Mtdh,Gbp8,Nlgn2,Mycl,Rbl1,Cd40,Lpcat2,Tnfaip2,Parp3,Pou3f1,Nqo1,P4ha1,Rpgrip1l,Max,Fscn1,Col27a1,Lipg,Insl6,Mapkbp1,Plk3,Tuba4a,Tnf,Pcgf5,Tcf4,Stxbp1,Rnf135,Selenow,Rasgrp1,Rras2,Tmem123,Ccl12,Acpp,Armc8,St3gal6,Asah2,Parp10,Cpd,Taf4b,Angpt1,Ikzf1,Prpf38a,Etnk1,Dse,Pilrb1,Pstpip2,Usp53,Gpr18,Frmd4a,Crbn,Mx1,Foxp4,Marco,Slc31a1,Marcksl1,Scarf1,Chmp4b,Mvp,Tmod3,Pfkfb3,Mul1,Ripk2,Usp25,Tmem178,Rnaset2a,Dgka,Ccne1,Hap1,Ifi203,Casp1,Hsd17b7,B3gnt5,Casp4,Esd,Pkp4,Rubcnl,Fas,Frmd6,Hvcn1,Papss2,Edn1,Rai14,Trip13,Rhoc,Ogfr,Casp7,Ccr3,Ptgir,Mtmr14,Cers6,Ep400,Lnpep,Irf4,Svbp,Itga4,Naa25,Serpina3g,Fchsd2,Gbp7,Plpp3,Ppp1r15b,Map2k4,Dach1,Rab21,Il10,Cnp,Irf1,Tnfsf14,Pcx,Relb,Itgav,Cemip2,Gja1,Il4i1,Hk2,Dtx2,Ppp2r3a,Hmga2,Dram1,Fubp1,Pdgfc,Palld,Slc7a2,Extl2,Vasp,Sap30,Cflar,Il6,Samhd1,Ctsc,Gem,Rel,Sema4a,Ubr4,Chd9,Prnp,Plk2,Grk3,N4bp1,Cd34,Slfn8,Egr1,Rgcc,Zhx2,Calcrl,Ext1,Cxcl14,Dnajb4,Rapgef5,Eno1,Vcam1,Kmt5a,Rnd1,Txn1,Il1rn,Kdm6b,Cgas,Gadd45b,Cnot4,Rcan1,Mark2,Ppp1r15a,Tor1aip2,Bcl6,Mmp25,Dusp4,Atp6v1d,Kitl,Pilra,Magohb,Plaat3,Setdb2,Egr2,Phlpp2,Gfpt1,Nlrc5,Ubash3b,Myd88,Met,H3f3b,Me1,Adar,Maff,Mcm10,Il12rb1,Stat1,Bcor,Usp35,Flrt3,Nlrc4,Spint2,Rin2,Hat1,Crkl,Ranbp2,Mcm6,Swap70,Hk3,Mthfd1l,Ikbke,Arl4a,Batf2,Piezo1,Lpar1,Phyh,Mafg,Xaf1,Dst,Ebi3,Pdgfb,Sec24a,Ampd3,4932438A13Rik,Tpst1,Kcnj2,Tfec,Egr3,Ggct,Stat3,Parp12,Sema3c,Smpdl3b,Gpr68,Ntng2,Triobp,Ccrl2,Birc2,Pde1b,Klf2,Ccl9,Olfr56,Ppp4r2,Vps54,Myc,Htr2a,Ell2,Rhou,Ap3b1,Ccl7,Cxcl1,Znrf3,Iigp1,Usp31,Vegfc,Ddit4,Sdc2,Scyl2,Glrx,Ezr,Spic,Gbp2,Pf4,Apaf1,Tlr9,Parp11,Clcf1,Chst11,Sell,Lyn,Tnip1,Il4ra,Slc7a11,Kremen1,Htr2b,Slc39a4,Pdzd11,Rims3,Usp18,Rab32,Pik3r6,Txnrd1,Cnn3,Hp,Csrp1,Fam20c,Rmdn3,Bcl2a1d,Gbp2b,Nes,Cd80,Adgrl2,Isg20,Fam129a,Cdyl,Coa5,Cd38,Degs2,Sat1,Slc39a13,Ccl5,Serpinb9,Cdkn2d,Ifnb1,Cutc,Phip,Vrk2,Fgr,Map3k6,Igf1r,Psip1,Tlr1,Prpf4,Malt1,Junb,Pde4b,Oas2,Snx2,Ccl3,Fcho2,Sod2,Ccl4,Agpat4,Stat4,Sh3bp4,Smox,Bcorl1,Pde3b,Eya4,Brwd3,Pml,Col4a2,Bfar,Rnd3,Hmox1,Plpp1,Gsta3,Uaca,Znrf1,Tdrd7,Rhoh,Tiparp,Cd300lf,Cyth3,Ifna4,1600014C10Rik,Atp10a,Tapbpl,Ptprj,Nmi,Stx11,Ass1,Cmpk2,Xcr1,Cd69,Gng4,Myo1b,Dyrk2,Cdc42ep2,Mitd1,Icosl,Trmt1l,Map4k4,Mtus1,H2-Q7,Trim21,Itgb8,Dhrs9,Nectin2,Enpp4,Hivep3,Slc12a9,Aim2,Adora2a,Rnf114,Mmp13,Mcoln2,Tgs1,Atp2b4,Ptger4,Mov10,Nr4a1,Tnfsf4,Xkr8,S100a8,Adgrg6,Gbgt1,Ust,Prkce,Cdk5r1,4930453N24Rik,Nfkb1,Ifnar1,Nfkbiz,Diaph2,Acp2,Il1b,Isg15,Sla,Slc39a14,Tet2,Pmaip1,Ifna1,Acp5,Btg2,Hsd17b12,Mlkl,Ttc39c,Phgdh,Lox,Il2rg,Pgap2,Nfkb2,Nmral1,Dck,Plek,Nrp2,Cpeb4,Srgn,Tnip3,Tmem67,Mosmo,Clic4,Daam1,Il12b,P2ry13,Tha1,Cd14,Ifitm1,Bnip3,Inpp5b,P2ry12,Rffl,Gm5431,Dusp6,Srxn1,Bcl2a1b,Cacybp,Katna1,Gys1,Ifi207,Eno2,Cdkn1a,Trim56,Spata13,Gpr35,Agtrap,Tnfsf10,Ifna6,Nck1,Fnbp1l,Mthfd2,Tyk2,Traf5,Dek,Pgk1,Inhba,Ptges,Rictor,Tlr6,Lcp2,Susd6,Tcea1,Nlrp3,Gramd1a,Rgs14,Spsb1,Dpy19l1,Gpc1,Wdr43,Ube2e1,Asb13,Kcna3,Heatr9,Flt1,Vcan,Slc25a25,Dock10,Stat2,Snx10,Peli1,Phlda1,Bcl2a1a,Cox17,Treml4,Gng11,Ktn1,Il15,Col18a1,Zc3h7a,Stx6,S1pr2,Ifrd1,Prag1,Gbe1,Ch25h,Prkx,Nr1h3,Tle3,Rab3ip,Slc25a22,Cebpd,Pdgfrb,Ccl8,Pdpn,Socs1,Gpr85,Eif2ak2,Plagl1,Map3k8,Ascc3,Stat5a,Kif5c,Rnf34,Slfn9,Ifna2,Socs3,Arid4a,Inpp1,Gm4951,Azi2,Golga3,Eef1e1,Birc3,Slamf8,Adrb2,Gtpbp2,Dcp2,Nfkbia,Evl,Pbx1,Adhfe1,Klf7,Osm,Dbnl,Sqstm1,Kctd12,Cd274,Lgals9,Il15ra,Mmp9,Plcl2,Syne2,Mmd,Pde7b,Ksr1,Traf1,Hilpda,Casz1,Ddx4,Nfil3,Klf6,Ppp1r12b,Ppp2r2a,Tpi1,Adora2b,Dusp5,Sde2,Plscr1,Ldha,Pik3cd,Hsph1,Spn,Icam1,Hk1,Uchl1,Kat2b,Irs2,Dr1,Atp13a1,Pfkl,Psd,Nt5c3,Gclc,Il13ra1,Cd180,Arid5b,Slc25a12,Daxx,Il1a,Fam162a,Rcsd1,Jun,Rsad2,Bambi,Tpx2,Cited2,Caml,Atf3,Kif9,Prdx1,Sbds,Top3a,Nfkbib,Mocs1,Prokr1,Trip10,Sele,Gfi1,Zc3h12a,Il18,Fgl2,Mdn1,Sgcb,Tomm70a,Rnf14,Gpd2,Tifa,Lrp4,Hlx,Znfx1,Stk40,Traf2,Rilpl1,Mthfr,Ifna5,Nek6,Ldlr,Smg7,Il18rap,Rrs1,Idi1,Micall2,Pvr,Tgfbi,Jarid2,Clec5a,Hivep2,Nfkbil1,Tut7,Nsd3,Ube2f,Hmga1,Sema4c,Cish,Socs7,Gng12,Stau1,Prkar2b,Dnaja1,Tgtp2,Sav1,Med13,Sgk3,Mmp14,Usb1,Dtx3l,Gclm,Rab11fip1,Tspo,Lnpk,Hspa1a,Cenpe,Cmklr1,Usp42,Kif3c,Intu,Cx3cr1,H60b,Asf1a,Klhl25,Pigv,Gk,Phlpp1,Fmnl2,Rars,Ccnd1,Nr4a3,Psmd10,Zmynd15,Crlf3,Dnaaf3,Casp3,Rtp4,Ikbkg,Asap3,Alas1,Rhof,Tmtc2,Pttg1,Mppe1,Mapkapk2,Mdm2,Gpr132,Dusp8,Jag1,Ciita,Atp11b,Ccnd2,Itga5,Hif1a,Ap3m2,9930111J21Rik1,Kdm4a,Ddhd1,Trem1,Fbxo4,Thbs1,Mt1,Cacnb3,Prdm9,Tagap,Rab10,Notch2,Hmgcs1,Ube2e2,Fut8,Plod2,Slc4a7,Pdlim7,Plod3,Gdf15,Fabp7,Cx3cl1,Mdfic,Cacna1d,Kdr,Gbp9,Col11a2,Gch1,Arid5a,Fcgr2b,Irgm1,Psat1,Serp1,Rcl1,Zfp281,Ift57,Mpp7,Ripk3,Cysltr2,Cycs,Trib1,Cxcl3,Prdx5,Mndal,Gnb4,Apba1,Optn,Dnase1l3,Pou2f2,Abcc4,Fam111a,Lrch1,Cxcl10,Ptafr,P4ha2,Ero1l,Klrk1,Ak4,Hcls1,Gbp3,Tapbp,Lcn2,Lst1,H2-Ab1,Rbms1,Itpkc,Hck,Src,Tnks1bp1,Dennd1b,Aff1,Dock4,Spry2,Csf3r,Csrnp1,Dusp16,Ppa1,Tgtp1,Ifih1,Kmo,Zeb1,Rnf19b,Dync1i2,Dcp1a,Plagl2,Fcgr4,Rsbn1,Pde5a,Myo10,Hopx,Trim12a,Cenpj,Mecp2,Ppp2r1b,Dcun1d3,Tulp3,Phactr4,St3gal1,Maml2,Dio2,Stip1,Parp14,Ppfia3,Pgs1,Slc9a1,Fcgr1,Parp8,Ahr,Sdc1,Ifi209,Atp11a,Lmo4,Ptch1,Helz2,Hhex,Grina,Trim13,Irf8,Axl,Acsl5,Gpsm2,Ier3,Arf4,Cox18,Minpp1,Ahrr,Ankib1,Mturn,Abr,Olr1,Fos,Rnaset2b,Higd1a,Acsl1,Ifit1,Atm,Tent4a,Upp1,Dusp2,Rgs3,Tpm4,Stoml1,Arhgef3,Whamm,Ltbp2,Tank,Rab9,Hspa1b,Timeless,Cxcl2,Srm,Nod1,Wars,Nox1,Msr1,F830016B08Rik,Fignl2,Larp1,Fndc3a,Dusp28,C3,Cd74,Treml2,Gsdmd,Actb,Fpr1,Rnf31,Sec24b,Psmb6,Ift22,Zswim4,Ifi204,Trim36,Fzd1,Syk,Ago3,Ccnj,Zc3h12c,Pim2,Zyx,Ciapin1,Ccr1,Rab20,Noct,Pik3r5,Milr1,Prdm1,Pim1,Clec4e,Clec4d,Tlr2,Themis2,Mx2,Adgre4,Lipe,Vcpip1,Flnb,Gm4841,Notch1,Pid1,Rgs1,Itgal,Irak2,Smc5,Gbp4,Wdr59,Nos2,Endod1,Parp9,Ifi208,Irgm2,Sesn3,Mcmbp,Htra1,Scn1b,Spred1,Cxcl9,Tlk2,Tnfsf8,Aoah,Asns,Csf3,Gcnt2,Igtp,Lrp8,Tap2,Sgms2,Serpine1,Tmsb10,Tmem176b,Carmil1,Adap2,Nod2,Pla2g7,Flrt2,Nfkbid,Tsku,Stap1,Xrn1,Homer1,Tent2,D16Ertd472e,Sp110,Clic5,Cop1,Morc3,Zfp36,Irak3,Gadd45g,Ehd1,Egln3,Ets2,Abcb1a,Hdc,Hinfp,Plaur,Acvr1,Plau,Cdc42ep4,Hdac1,Rgl1,Yju2 |
| 1.181e-22 | -50.49 | WIELAND_UP_BY_HBV_INFECTION | MSigDB lists | WIELAND_UP_BY_HBV_INFECTION | 104 | 45 | 15632 | 1249 |
Igsf6,Ctsc,Sod2,Plac8,H2-Q4,Ifi207,Ifi214,Pttg1,Ifi203,Psme2,Isg20,Ifi211,Mndal,Lap3,Rnaset2b,Pik3cd,Rab20,Ifi204,Stat1,Dram1,Tapbp,Fgl2,Ifi209,Ifi205,Psmb9,H2-Q6,Ifi213,Gbp2,Cd38,Cd83,Psmb10,Cd74,H2-Q7,Psme1,Parp12,Wars,Ifi208,Ube2l6,Rnaset2a,Ccl5,Rgl1,Sp110,Cxcl10,Mcm6,H2-Ab1 |
| 1.281e-22 | -50.41 | GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | MSigDB lists | GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 1301 | 205 | 15632 | 1249 |
Ezr,Agrn,Fos,Edn1,Prkce,Nod2,Abr,Egr1,Nlrp3,Gng11,Htr2a,Tnfrsf14,Atp2b4,Ccne1,Irf8,Casp4,Ptch1,Jag1,Sirt1,Stat1,Adrb2,Pfkl,Socs7,Gfi1,Src,P2ry12,Birc2,Cd40,Rbbp8,Casp3,Egr2,Mdm2,Ccnd1,Mthfr,Calcrl,Cd180,Hif1a,Socs1,Agtrap,Tnfrsf8,Notch1,Hck,Nampt,Cnp,Klf2,Pdgfb,Csf3,Ptger4,Ldha,Zc3h12a,Ptafr,Cxcl10,Thbs1,Gng12,Pf4,Klf3,Ptpn2,Bnip3,Pla2g4a,Fas,Cdkn2d,Kat2b,Nr1h3,Cdk5r1,Cd80,Tspo,Olr1,Ahr,Me1,Tnfrsf1b,Ednrb,Cav1,Pid1,Nos2,Zeb1,Il18rap,Cpeb4,Hmgcs1,Mtdh,Ptgir,C3,Tnip3,Lpar1,Gfpt1,Stat5a,Homer1,Stat3,Mecp2,Prdx5,Plk3,Fabp3,Gnb4,Pdgfc,Cd38,Irak3,Gja1,Serpine1,Pdgfrb,Stxbp3,Hp,Hmox1,Ripk2,Gng4,Il18,Nr4a3,Cxcl1,Lrp11,Ptges,Htr2b,Il1b,Cx3cr1,Nfkbia,Ccl12,Jun,Il6,Peli1,Il18bp,Nqo1,Mapkapk2,Lrp8,Phip,Prdx1,Plau,Pde3b,Pdk3,Gna15,Il10,P2ry2,Tnfsf4,Socs3,Acsl1,Tlr2,Igf1r,Prkar2b,Axl,Dusp1,Casp1,Ifnar1,Timp1,Rhoq,Gsr,Nfkbil1,Icam1,Sphk1,Sell,Nod1,Txn1,Junb,Gch1,Cd86,Btg2,Kdm6b,Ptgs2,Pim1,Il12b,Cmpk2,Nr4a1,Eif2ak2,Sod2,Ass1,Stap1,Ifnb1,Col18a1,Sdc1,Irs2,Il15,S100a8,Nfkb1,Ppp1r15b,Casp8,Slc9a1,Nfkbib,Slpi,Ptk2,Max,Trib1,Lyn,Jak2,Cdkn1a,Klf6,Tnf,Txnrd1,Traf2,Tnc,Cycs,Sele,Errfi1,Cd14,Tnfaip3,Pde4b,Ccl5,Ppp1r15a,Asns,Atp6v1d,Fosb,Rab10,Sh3bp4,Rapgef2,Inhba,Fzd1,Cxcl2,Trib3,Vcam1,Irak2,Nfkb2 |
| 1.309e-22 | -50.39 | GSE17721_CTRL_VS_LPS_2H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_2H_BMDC_DN | 186 | 61 | 15632 | 1249 |
Birc3,Casp4,Lmo4,Csf1,Flnb,Plscr1,Mtdh,Ebi3,Ell2,Map2k4,Acsl1,Clcf1,Cacna1d,Cdkn1a,Adhfe1,Nfkbia,Sqstm1,Ccr3,Mmp14,Ccl2,Vcan,Mllt6,Dtnb,Atf3,Palld,P2ry14,Mul1,Col4a2,Rras2,Clec4e,Olr1,Rgl1,Samsn1,Fzd5,St3gal1,Smc5,Adora2b,Chic2,Arid5b,Map3k8,Vcam1,Nfkb2,Inpp1,Gypc,Spryd7,Ttc39c,Klhl25,Timp1,Cd40,Nr3c1,Slc15a3,Ccng2,Ier2,Lif,Calcrl,Upp1,Arg2,Ifih1,Crlf3,Tnfrsf8,Cd38 |
| 1.490e-22 | -50.26 | negative regulation of signaling | biological process | GO:0023057 | 1286 | 183 | 20694 | 1406 |
Sod2,Fzd1,Mapkbp1,Tnf,Sh3bp4,Pde3b,Stxbp1,Bambi,Atf3,Eya4,Asah2,Bfar,Prdm1,Uchl1,Cdkn2d,Ccl5,Rabgef1,Icam1,Igf1r,Pfkl,Phip,Cd74,Gclc,Pde4b,Rpgrip1l,Aida,Bcl2a1d,Ptgs2,Atm,Higd1a,Dusp2,Rgs3,Cd38,Hsph1,Fam72a,Dusp5,Tank,Klf7,Chst11,Lyn,Cav1,Tnip1,Osm,Kremen1,Trim30a,Myadm,Itpr1,Acod1,Ptch1,Htr2b,Grina,Dhx58,Hhex,Plcl2,Ier3,Mmp9,Sirt1,Rab11fip1,Atp2b4,Cx3cr1,Il10,Acvr1,Plaur,Tnfsf4,Phlpp1,Hdac1,Irf1,Serpine1,Nod2,Nfkbid,Socs7,Dnaja1,Tsku,Stap1,Edn1,Cish,Sgk3,Mmp14,Ptgir,Irak3,Gclm,Irf4,Lrp4,Mul1,Sesn3,Mvp,Spred1,Htra1,Ptprj,Map4k4,Nfkbil1,Dyrk2,Hmox1,Uaca,Pid1,Rgs1,Rhoh,Notch1,Cd300lf,Zc3h12a,Rffl,Cx3cl1,Nlrc5,Ubash3b,Dusp6,Bcl2a1b,Casp8,Fcgr2b,Nck1,Gpr35,Met,Egr1,Pmepa1,Tnip3,Mosmo,Rcan1,Il1rn,Spred3,Bcl6,Gdf15,Dusp4,Cflar,Dusp8,Jag1,Il6,Hif1a,Dusp1,Samhd1,Bmp2,Thbs1,Plk2,Grk3,Prnp,Plek,Psmd10,Itgav,Ikbkg,Il1b,Hmga2,Ppp2r3a,Pim3,Mdm2,Socs1,Tulp3,Phactr4,Rnf34,Znrf3,Socs3,Ezr,Parp14,Ddit4,Scyl2,Glrx,Adrb2,Nfkbia,Tlr9,Slc30a1,Pf4,Spry2,S1pr2,Dusp16,Tle3,Htr2a,Ptpn2,Lpar1,Gpc1,Lif,Map2k1,Smpdl3b,Nr3c1,Bcl2a1a,Src,Ncoa5,Tnfaip3,Trib1,Adar,Vasn,Stat1,Tlr6,Errfi1,Rgs14,Nlrp3,Optn |
| 1.565e-22 | -50.21 | GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | MSigDB lists | GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | 170 | 58 | 15632 | 1249 |
Hk2,Maff,Parp12,Wars,Nmi,Ube2l6,Tap2,Ifit1bl2,Nampt,Slc31a2,Sp110,Trafd1,Il15ra,Pcdh7,Cxcl10,Ak4,Ripk2,Herc6,St3gal1,Rnf19b,Atp10a,Dock10,Slc15a3,D1Ertd622e,Tank,Psmb9,Swap70,Parp8,Ifit2,Psmb10,Socs1,Usp18,Stat2,Icam1,Ddx58,Slc30a4,Malt1,Xaf1,Tdrd7,Rnf19a,Plscr1,Zfp36,Csf1,Ogfr,Ifit3,Psmb8,Lyn,Ifit3b,Rab20,Irf1,Trib1,Ifi35,Il6,Ifit1bl1,Eif2ak2,Flt1,Tap1,Atf3 |
| 1.571e-22 | -50.20 | GSE40685_TREG_VS_FOXP3_KO_TREG_PRECURSOR_DN | MSigDB lists | GSE40685_TREG_VS_FOXP3_KO_TREG_PRECURSOR_DN | 181 | 60 | 15632 | 1249 |
Pstpip2,St3gal5,C1rl,Cenpj,Lap3,Casp4,Orai2,Jak2,Casp7,Ifi35,Stat1,Socs3,Parp11,Pla2g4a,Parp14,Ift57,Dtnb,Hivep2,Ifit1bl1,Nlrc5,Rnf114,Znfx1,Il15,Me1,Ddx60,Fpr2,Xrn1,H2-Aa,Il12rb1,Oas2,Nampt,Ifit1bl2,Snx10,Rgl1,Gch1,Tnfsf10,Epsti1,Glrx,Sp110,H2-Ab1,Gpr85,Stat3,Cish,Setdb2,Rsad2,C1ra,Ifit2,Tnf,Casp1,Cd40,Batf,Crlf3,Cd38,Olfml3,Psme1,Aim2,Stat2,Cd74,Gbp3,Ifih1 |
| 1.571e-22 | -50.20 | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN | MSigDB lists | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN | 181 | 60 | 15632 | 1249 |
Pde4b,Sipa1l1,Cd86,Ppp1r15a,Slc7a5,Phlda1,Ext1,Btg2,Fndc3a,Ptger4,Smox,Ptprj,Cxcl10,Nr4a3,Grina,Tnfsf10,Clic4,Glrx,Ehd1,Tnf,Arid5a,Ttc39c,Cish,Slc39a4,Ifi44,Stat3,Nfkbie,Fgl2,Mxd1,Hif1a,Icam1,Stat2,Mdfic,Tnfrsf1b,Zfp36,Trim14,Isg20,Sirt1,Trib1,Rgs1,Adam19,Ccl4,Znrf1,Cdkn1a,Gfi1,Pmepa1,Nfil3,Sqstm1,Nfkbia,Gadd45b,Jun,Ets2,Tspan3,Dusp2,Irf4,Nek6,Egr1,Atf3,Abr,Atp2b4 |
| 1.595e-22 | -50.19 | GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_DN | MSigDB lists | GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_DN | 154 | 55 | 15632 | 1249 |
Ifi44,Gpr68,Tapbp,Treml2,Nfkbie,Cst7,Axl,Tnf,Oas3,Irak3,Rhoh,Nupr1,Aim2,Socs1,Traf1,Cd74,Hap1,Dgka,Psd4,Hopx,Plat,Il1rn,Epsti1,Rnf19b,Ptger4,Pim1,Slc43a3,Gadd45g,Chst11,Gadd45b,Nlrc5,Gsdmd,Slamf7,Clec4e,Atf3,Sgms2,Slpi,Isg20,Cd69,Rap1gap2,Rasgrp1,Il18rap,Ccrl2,Stat4,Pla2g7,Jdp2,Tnfrsf1b,Gem,Casp4,Lcn2,Itgal,Cd300lf,Rgs1,Dram1,Casp7 |
| 1.738e-22 | -50.10 | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | MSigDB lists | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | 149 | 54 | 15632 | 1249 |
Il4ra,Plau,Jun,Tiparp,Cited2,Plac8,Hivep2,Itgav,Sqstm1,Agrn,Flrt3,Chst11,Il6,Dnajb4,Ier3,Cdkn1a,Ldlr,Rel,Sema3c,Slc39a14,Sphk1,Lif,Tnfaip3,Bmp2,Tpst1,Bcl6,Birc2,Tank,Klf6,Dusp1,Nfkbie,Tapbp,Ccng2,Cebpd,Irgq,Tnc,Stat3,Ptger4,Kdm6b,Plaur,Pcdh7,Cxcl1,Nfkb2,Thbs1,Serpinb2,Plk2,Serpine1,Nampt,Slc31a2,Junb,Inhba,Maff,Cxcl2,Phlda1 |
| 1.866e-22 | -50.03 | GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_DN | MSigDB lists | GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_DN | 176 | 59 | 15632 | 1249 |
Tax1bp1,Clcn7,Tmem67,Stat1,Tmod3,Pik3cd,Slamf9,Smpdl3b,Rnf31,Gpc1,Clec4e,Tspo,Rbm43,Col4a2,Rbms2,Kif9,Slc28a2,Atf3,Sass6,Coa5,Ppp2r5a,Bbx,Abcb1a,Rnf114,Tnfsf10,Plcl2,Dcbld2,Herc6,Tlr3,Slamf8,Grina,Dgka,Car13,Rgl1,Slc7a8,Irf7,Cnp,Cd86,Tap2,Bfar,Pml,Psme1,Socs1,Usp18,Hif1a,Ddx58,Cd180,Rab19,Rab9,Tnfsf8,Dbnl,Minpp1,Casp3,Gypc,Parp8,Armcx6,Mtus1,Homer1,Arhgef3 |
| 2.065e-22 | -49.93 | negative regulation of programmed cell death | biological process | GO:0043069 | 942 | 148 | 20694 | 1406 |
Cdkn2d,Irs2,Serpinb9,Ccl5,Hk1,Icam1,Mtdh,Igf1r,Phip,Cd74,Il1rn,Gclc,Bnip3,Bcl6,Rnf31,Insl6,Ednrb,Nqo1,Rffl,Sod2,Jun,Kitl,Tnf,Plk3,Cx3cl1,Daxx,Cited2,Kdr,Stxbp1,Bcl2a1b,Cdkn1a,Casp8,Ciapin1,Eya4,Ccl12,Fcgr2b,Asah2,Pim2,Bfar,Met,Angpt1,Cav1,Chst11,Nfkb1,Tnfsf14,Prkce,Psmd10,Nr4a3,Clcf1,Casp3,Itgav,Htr2b,Ikbkg,Grina,Axl,Il1b,Pim3,Mdm2,Btg2,Arf4,Arel1,Ier3,Mmp9,Sirt1,Bcl2a1d,Cflar,Ptgs2,Il6,Nes,Ccnd2,Higd1a,Dusp1,Itga5,Hif1a,Casp2,Hsph1,Cpeb4,Plk2,Tax1bp1,Thbs1,Cd38,Mt1,Prnp,Hspa1b,Spry2,Serpine1,Nod2,Nupr1,Fas,Dnaja1,Edn1,Serpinb2,Birc2,Ptk2,Sgk3,Myc,Gclm,Pdgfrb,Stat5a,Pdpn,Adora2a,Eif2ak2,Mecp2,Rnf34,Socs3,Cx3cr1,Birc3,Il10,Acvr1,Plaur,Nr4a1,Glrx,Tnfsf4,Map2k4,Hdac1,Slc9a1,Pf4,Tnfaip3,Adar,Pim1,Hmox1,Sphk1,Prdx5,Jak2,Timp1,Prokr1,Trip10,Notch1,Plac8,Optn,Zc3h12a,Hk3,Il18,Stk40,Traf2,Arg2,Hcls1,Map2k1,Map4k4,Nr3c1,Clec5a,Egr3,Peli1,Asns,Src,Bcl2a1a,Hck,Stat3 |
| 2.105e-22 | -49.91 | GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1031 | 174 | 15632 | 1249 |
Ccr1,Fzd5,Osm,Pdgfrb,Map2k1,Psmb6,Ripk2,Adora2b,Il18,Map3k8,Kitl,Gcnt2,Htr2b,Il1b,Stat3,Glipr2,Rbpms,Tab2,Psmb10,Pdgfc,Ifna2,Ccl3,Tnfrsf1b,Ednrb,Cav1,Rictor,Tlr9,Mmp9,C3,Lpar1,Dnajb2,Gadd45b,S1pr2,Gadd45g,Ifna5,Mid1,Fas,Kat2b,Cx3cl1,Cdk5r1,Pilrb2,Sdc4,Cd80,Jarid2,Pdgfb,Ifna6,Csf3,Ptger4,Zc3h12a,Fpr1,Thbs1,Plaur,Vegfc,Hsph1,Src,Cd40,Birc2,Ccnd1,Psma6,Malt1,Lif,Il1a,Trim12c,Mdfic,Birc3,Psmb8,Cysltr2,Ksr1,Sirt1,Rasgrp1,Nox1,Adrb2,Clcf1,Flt1,Map3k6,Psmd10,Edn1,Prkce,Nod2,Ccnd2,Arrdc4,Htr2a,Tnfrsf14,Atp2b4,Angpt1,Plek,Gdf15,Ccl5,Dusp6,Ppp1r15a,Lcp2,Rapgef2,Inhba,Fzd1,Tlr3,Crkl,Trib3,Pilrb1,Irak2,Tnf,Traf2,Bcl6,Hspa2,Nupr1,Rnf139,Cd74,Atm,Ikbkg,Jdp2,Dcun1d3,Csf1,Psme2,Mmd,Sema4c,Ptk2,Itga5,Lyn,Jak2,Rap2c,Ccl4,Cdkn1a,Spn,Eif2ak2,Sqstm1,Syk,Stap1,Ifnb1,Pde5a,Mul1,Tpx2,Il15,Txn1,Pik3r6,Nmi,Tnfsf15,Dusp5,Pim1,Il12b,Lrp4,Psmb9,Dbnl,Acvr1,Acvrl1,Ube2e1,Psme1,Pml,Icam1,Sphk1,Nod1,Bmp2,Ripk3,Daxx,Socs3,Acvr1b,Acsl1,Hcls1,Kdr,Prkar2b,Cenpe,Pik3r5,Ccl12,Jun,Spry2,Ppp2r5a,Peli1,Ccl2,Il6,Lrp8,Mapkapk2,Tlr6,Ccl22,Ifna1,Fbxo4,Mark2 |
| 2.167e-22 | -49.88 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_DN | 182 | 60 | 15632 | 1249 |
Ccl4,Kdr,Ifi35,Casp7,Dck,Trim21,Ociad1,Ppp4r2,Psme2,Ccrl2,Eef1e1,Tor3a,Zc3h12c,Gbp7,Rras2,Sgcb,Chmp4b,Tap1,Ddx60,Coa5,P2ry14,Dusp2,Ccl2,Il18bp,Klf3,Rnf114,Mitd1,Stip1,Htr2b,Sp110,Atp10a,Fndc3a,Psmb6,Cox18,Tapbpl,St7,Caml,Ube2l6,Sap30,Snx2,Tbc1d13,Ccnj,Slc13a3,Rgl1,Slc7a8,Cd274,Vps54,Rnf34,Apaf1,Rhoc,Psme1,Rnf135,Batf2,Gbp4,Gbp9,Mdm2,Tlk2,Parp8,Serp1,Tpst1 |
| 2.190e-22 | -49.87 | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP | 171 | 58 | 15632 | 1249 |
Ifit3b,Parp11,Phf11d,Ifi204,Stat1,Oasl1,Ifi35,Mndal,Ifit3,Ifi203,Xaf1,Oas1a,St3gal5,Psme2,Ifi211,Trim14,Rtp4,Ifi214,Ddx60,Phf11c,Mark2,Ifi207,Zbp1,Adar,Phf11a,Eif2ak2,Ifit1bl1,H2-Q4,Il2rg,Oas1g,Herc6,Sp110,Irf7,Brd2,Gch1,Ifit1bl2,Oas2,Parp12,Il12rb1,Nmi,Ifi208,Ube2l6,Isg15,Ifih1,Usp18,Pml,H2-Q7,Smg7,Ifi205,Oas3,Ifi209,H2-Q6,Psmb9,N4bp1,Ifi213,Phf11b,Rsad2,Ifi44 |
| 2.370e-22 | -49.79 | negative regulation of cell communication | biological process | GO:0010648 | 1281 | 182 | 20694 | 1406 |
Tlr9,Adrb2,Slc30a1,Nfkbia,Pf4,Scyl2,Glrx,Ddit4,Ezr,Parp14,Socs3,Rnf34,Znrf3,Tulp3,Phactr4,Socs1,Ptpn2,Htr2a,Tle3,Dusp16,S1pr2,Spry2,Bcl2a1a,Src,Nr3c1,Smpdl3b,Map2k1,Lif,Gpc1,Lpar1,Optn,Nlrp3,Rgs14,Errfi1,Stat1,Tlr6,Vasn,Adar,Ncoa5,Tnfaip3,Trib1,Met,Gpr35,Nck1,Fcgr2b,Casp8,Bcl2a1b,Dusp6,Ubash3b,Nlrc5,Cx3cl1,Rffl,Gdf15,Dusp4,Bcl6,Spred3,Il1rn,Rcan1,Mosmo,Tnip3,Pmepa1,Egr1,Plek,Prnp,Grk3,Thbs1,Plk2,Samhd1,Bmp2,Hif1a,Dusp1,Il6,Jag1,Dusp8,Cflar,Mdm2,Ppp2r3a,Hmga2,Pim3,Il1b,Ikbkg,Itgav,Psmd10,Irf1,Phlpp1,Hdac1,Tnfsf4,Plaur,Acvr1,Il10,Cx3cr1,Atp2b4,Rab11fip1,Irf4,Gclm,Irak3,Ptgir,Sgk3,Mmp14,Cish,Tsku,Stap1,Edn1,Dnaja1,Socs7,Nod2,Nfkbid,Serpine1,Dyrk2,Nfkbil1,Map4k4,Ptprj,Htra1,Spred1,Sesn3,Lrp4,Mul1,Zc3h12a,Cd300lf,Notch1,Rhoh,Rgs1,Pid1,Uaca,Hmox1,Prdm1,Bfar,Asah2,Eya4,Atf3,Stxbp1,Bambi,Pde3b,Sh3bp4,Tnf,Mapkbp1,Fzd1,Sod2,Aida,Pde4b,Rpgrip1l,Gclc,Cd74,Phip,Igf1r,Pfkl,Icam1,Ccl5,Rabgef1,Cdkn2d,Uchl1,Tank,Dusp5,Cd38,Hsph1,Fam72a,Dusp2,Rgs3,Higd1a,Atm,Ptgs2,Bcl2a1d,Sirt1,Mmp9,Ier3,Plcl2,Hhex,Dhx58,Grina,Itpr1,Htr2b,Ptch1,Acod1,Trim30a,Myadm,Tnip1,Osm,Kremen1,Klf7,Chst11,Lyn,Cav1 |
| 2.459e-22 | -49.76 | HALLMARK_HYPOXIA | MSigDB lists | HALLMARK_HYPOXIA | 188 | 61 | 15632 | 1249 |
Tnfaip3,Gys1,Jmjd6,Errfi1,Ccng2,Prdx5,Nr3c1,Cp,Slc2a1,Eno1,P4ha2,Dusp1,Klf6,Plaur,Glrx,Pgk1,Gcnt2,Pim1,Adora2b,Tgfbi,Ak4,Lox,Hmox1,Ldha,Maff,Hk2,Pdgfb,Ext1,Ddit4,Sap30,Ppp1r15a,Serpine1,Klf7,Pfkfb3,Sdc4,Gpc1,Pgm1,Gbe1,Irs2,Atf3,Tpi1,Sdc2,Il6,Fos,Tiparp,Cited2,Jun,Plac8,Pfkl,Fam162a,Cdkn1a,Nfil3,Ier3,Isg20,Zfp36,Ampd3,Cav1,Pdk3,Eno2,P4ha1,Hk1 |
| 2.852e-22 | -49.61 | positive regulation of cell communication | biological process | GO:0010647 | 1846 | 235 | 20694 | 1406 |
Il6,Hif1a,Acvr1b,Cflar,Mid1,Jag1,Plk2,Thbs1,Cacnb3,Casp2,Bmp2,Ctsc,Tlr3,Gja1,Ikbkg,Crlf3,Nfkb1,Tnfsf14,Prkce,Mlkl,Pdgfc,Pmaip1,Il1b,Ppp2r3a,Nlrc5,Kdr,Sik3,P2ry12,Cacna1d,Kitl,Cx3cl1,Mdfic,Nck1,Gpr35,Irgm1,Acvrl1,Met,Tnfsf10,Myd88,Serp1,Casp8,Fcgr2b,Notch2,Bnip3,Gdf15,Cd14,Il1rn,Traf3ip2,Cgas,Il12b,Spred3,Gadd45b,Pdgfb,Lif,Usp12,Flt1,Lpar1,Tnfsf15,Ikbke,Treml4,Gpr68,Nr3c1,Peli1,Src,Bcl2l11,Stat3,Fpr2,Hcls1,Map2k1,Zbp1,Sphk1,Crkl,Jak2,Tlr6,Tnfaip3,Irf7,Inhba,Rictor,Cysltr2,Traf5,Ripk3,Clec4n,Rgs14,Akt3,Zc3hav1,Scimp,Mecp2,Ppp2r1b,Eef1e1,Rbpms,Cenpj,Map3k8,Glipr2,Ccl7,Eif2ak2,Slc9a1,Apaf1,Adrb2,Tlr9,Ccl2,Parp14,Glrx,Spry2,Nupr1,Csf1,Hcar2,Il15,Myc,Pde5a,Ccl8,Htr2a,Ptpn2,Fzd5,Plagl2,Pdgfrb,Ptk2,Ccl9,Prag1,Kmo,Nr1h3,Cyfip1,Atm,Ksr1,Ptgs2,Rapgef2,Cd38,Plscr1,Adora2b,F10,Sqstm1,Rims3,Htr2b,Cav1,Lyn,Osm,Clcf1,Ccl22,Sirt1,Mmp9,Trim13,Lgals9,Axl,Pik3r6,Dhx58,Hhex,Syk,Cited2,Bambi,Stxbp1,Ccl4,Jun,Fam162a,Rsad2,Mapkbp1,Tnf,Ccl3,Il1a,Daxx,Pik3r5,Angpt1,Atf3,Ccr1,Pml,Ccl12,Ago3,Rasgrp1,Acpp,Pim2,Ankrd17,Map3k6,Nlgn2,Fgr,Mtdh,Cd40,Igf1r,Nox1,Phip,Ifnb1,Nod1,Irs2,Ccl5,Icam1,Rnf31,Malt1,Cd74,Cd180,C3,Tlr1,Spred1,Traf2,Ripk2,Parp9,Mul1,Tifa,Irgm2,Tab2,Wdr59,Wdfy1,Map4k4,Casp4,Gcnt2,Csf3,Hap1,Casp1,Ptprj,Marco,Gpr18,Tlr2,Cd300lf,Irak2,Zc3h12a,Itgal,Il18,Gfi1,Notch1,Ptger4,Adora2a,Phlpp1,Hdac1,Cx3cr1,S100a8,Il10,Intu,Acvr1,Plaur,Map2k4,Stau1,Edn1,Stap1,Sema4c,Nod2,Fas,Gadd45g,Ddx60,Nectin2 |
| 2.899e-22 | -49.59 | NAGASHIMA_NRG1_SIGNALING_UP | MSigDB lists | NAGASHIMA_NRG1_SIGNALING_UP | 161 | 56 | 15632 | 1249 |
Ldlr,Clcf1,Nfil3,Itpkc,Egr3,Ier3,Trib1,Zfp36,Isg20,Egln3,Gem,Rel,Pfkfb3,Palld,Egr1,Atf3,Irs2,Dusp2,Myc,Edn1,Dusp4,Ifrd1,Flrt3,Gadd45b,Nr4a1,Ezr,Jun,Tiparp,Ets2,Zyx,Fos,Inpp1,Plaur,Dusp5,Kdm6b,Nr4a3,Map3k8,Phlda1,Maff,Gdf15,Junb,Fosb,Klf2,Ppp1r15a,Lif,Ier2,Arg2,Jmjd6,Socs1,Sertad3,Sphk1,Dusp8,Egr2,Dusp1,Klf6,Homer1 |
| 2.913e-22 | -49.59 | GO_CELL_DEATH | MSigDB lists | GO_CELL_DEATH | 914 | 160 | 15632 | 1249 |
Csrnp1,Nupr1,Plk3,Aim2,Cd14,Rnf34,Traf5,Tnfaip3,Cd38,Apaf1,Ifit2,Tnf,Ifi209,Traf2,Tnfsf8,Cycs,Prdx5,Ripk2,Hmox1,Xkr8,Tlr3,Map3k8,4930453N24Rik,Trib3,Ikbke,Kitl,Il1b,Acp2,Gja1,Fzd5,Ppp1r15a,Ddit4,Inhba,Nek6,Cdkn2d,Fas,Tpx2,Mul1,Ifi214,Ciapin1,Tspo,Pim3,Dnase1l3,Ahr,Olr1,Ifi207,Sod2,Itgav,Sqstm1,Bcl2a1b,Gadd45b,Spn,Gsdmd,Nlrc4,Ggct,Bnip3,Ctsc,Gclm,Ift57,Gadd45g,Phlpp1,Optn,Uaca,Pim2,Mmp9,Dram1,Ptk2,Max,Map2k4,Ifi204,Tax1bp1,Ppp2r1b,Notch2,Polr2g,Jak2,Cdkn1a,Fam162a,Nfkb1,Ikbkg,Tnfrsf1b,S100a8,Atm,Casp8,Mndal,Cav1,Ifi211,Slc9a1,Egln3,Xaf1,Pml,Traf1,Il1a,Tnfrsf8,Bfar,Nod1,Notch1,Daxx,Ripk3,Casp1,Ifi213,Src,Ifi205,Cd40,Birc2,Itpr1,Rffl,Pde1b,Casp3,Mlkl,Bcl2a1d,Mdm2,Zc3h12a,Traf3ip2,Serpinb9,Pim1,Tnfsf10,Thbs1,Clic4,Bcl2a1a,Hcar2,Plaur,Card6,Asah2,Tnfsf15,Ifi208,Phlda1,Adora2a,Hk2,Nlrp3,Plagl1,Htr2a,Gclc,Plau,Tnfrsf14,Bcl2l11,Nfkbia,Jun,Psmd10,Prkce,Il6,Myc,Dyrk2,Stat1,Casp7,Tlr2,Ier3,Irf1,Acvr1b,Tmem123,Cflar,Tmem219,Eif4g2,Birc3,Casp4,Lcn2,Tnfsf14,Plscr1,Ifi203,Casp2,Sirt1 |
| 3.105e-22 | -49.52 | regulation of lymphocyte activation | biological process | GO:0051249 | 422 | 89 | 20694 | 1406 |
Arg2,Ripk2,Hlx,H2-Ab1,Peli1,Egr3,Icosl,Ripk3,Tnfaip3,Tarm1,Il12rb1,Slamf7,Tnfrsf1b,Zc3h12a,Itgal,Il18,Fgl2,Nlrp3,Bst1,Ap3b1,Socs1,Slfn1,Adora2a,Stat5a,Ccl2,Irf1,Slamf8,Tlr9,Tnfsf4,Il10,Il15,Fas,Nfkbid,Nod2,Ctla2a,Ptpn2,Pde5a,Zeb1,Mmp14,Atm,Il6,Cd80,Il2rg,Prnp,Tnfsf9,Hsph1,Cd38,Spn,Cd86,Casp3,Nfkbiz,Ahr,Tnfsf14,Clcf1,Cav1,Tnfrsf14,Lyn,Il4ra,Pik3r6,Il1b,Cd274,Cd83,Il15ra,Lgals9,Axl,H2-Aa,Syk,Ikzf1,Myd88,Nck1,Prdm1,Il27,Rasgrp1,Fcgr2b,Sdc4,Cdkn1a,Vcam1,Cd40,Ccl5,Ifnb1,Irs2,Malt1,Samsn1,Bcl6,Cgas,Il12b,Parp3,Ccdc88b,Cd74 |
| 3.578e-22 | -49.38 | GSE17721_POLYIC_VS_CPG_2H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_2H_BMDC_DN | 178 | 59 | 15632 | 1249 |
Spred1,Slc25a25,Rnd3,Sdc1,Nlrp3,P2ry14,Pgs1,Nck1,Tlr6,Igsf6,Dusp2,Ccl2,Adhfe1,Slc7a11,Bcl2l11,Gfi1,Cd82,Dnajb4,Tlr2,Cd200,Jag1,Usp12,Nfkbib,St3gal5,Mdfic,Cd83,Batf,Fam133b,Spata13,Calcrl,Mdm2,Nr3c1,Ly75,Hsph1,Spryd7,Cst7,Usp53,Stip1,Dcbld2,Rcl1,Ptges,Tfec,Ppp2r2a,Vcam1,Plcl2,Ikbke,Fpr1,Smox,Atp10a,St3gal1,Sh3bp4,Tlr1,Phlda1,Lad1,Serpine1,Hsd17b12,Rgl1,Igsf9,Gdf15 |
| 3.578e-22 | -49.38 | GSE32986_UNSTIM_VS_GMCSF_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_STIM_DC_DN | 178 | 59 | 15632 | 1249 |
Lad1,Irf7,Rgl1,Mmp13,Slamf8,Osgin2,Ak4,Phf6,Dnaja2,Fndc3a,Fmnl2,Ppp2r2a,Pilrb1,Il1rn,Slfn9,Serpinb2,Traf2,Axl,Spryd7,Hdac1,Upp1,Socs1,Jmjd6,Arg2,Psme1,Hvcn1,Gnb4,Traf5,Myd88,Ube2f,Isg20,Procr,Psme2,Odc1,Mtdh,Casp7,Oasl1,Filip1l,Abcc1,Zcchc2,Idi1,Col27a1,Tnfaip2,Gramd1a,Agrn,Sbds,Ppp1r14b,Srm,Taf4b,Ncoa5,Cox17,Parp9,Ift57,Slfn8,Gmppb,Cx3cl1,Lrp8,Dusp14,Pilrb2 |
| 3.613e-22 | -49.37 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN | 151 | 54 | 15632 | 1249 |
D16Ertd472e,Nlrc5,Ifit1bl1,Hivep2,Peli1,Stard5,Parp14,Ddx60,Pnpt1,Slamf7,Zbp1,Zbtb5,Zc3h12c,Irf8,Ifit3,Abtb2,Xaf1,Plscr1,Ifit3b,Fam111a,Irf1,Dusp16,Oas3,Arid5a,Otud1,Tnf,Ifit2,Dhx58,Tlk2,Ifi44,Batf2,Isg15,Gbp3,Stat2,Pml,Csrnp1,Aim2,Mxd1,Tnfaip3,Cd38,Irf7,Plekha4,Gch1,Ifit1bl2,Tnfsf15,Ext1,Dusp5,Herc6,Atp10a,Kdm6b,Cmpk2,Epsti1,Il15ra,Irak2 |
| 4.016e-22 | -49.27 | GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 1648 | 241 | 15632 | 1249 |
Trib3,Arid5b,Il2rg,Crkl,Tlr3,Pilrb1,Nfkb2,Irak2,Lcp2,Ppp1r15a,Plek,Dusp6,Ccl5,Rapgef2,Tbc1d13,Fzd1,Trim26,Cd74,Asap3,Rgs3,Rab3ip,Sgk3,Traf5,Traf2,Tnf,Errfi1,Arhgap26,Sele,Hspa2,Dock10,Cycs,Lyn,Ptk2,Dennd2a,Cdkn1a,Jak2,Arf4,Ccl4,Casp8,Adap2,Mndal,S100a8,Dcun1d3,Nfkb1,Ikbkg,Mmd,Csf1,Slc9a1,Trim21,Nfkbib,Psme2,Cyth3,Tpx2,Mul1,Ifi214,Irs2,Nck1,Ifi207,Eif2ak2,Syk,Rapgef5,Psd,Rin2,Pde5a,Phactr4,Tor1aip2,Stap1,Pim1,Dusp5,Glrx,Plcl2,Tnfsf10,Pik3r6,Txn1,Gch1,Hap1,Tnfsf15,Ifi208,Icam1,Spata13,Fgr,Sphk1,Ube2e1,Psme1,Pml,Daxx,Ripk3,Rhoc,Nod1,Bmp2,Ahsa1,Psmb9,Ifi205,Eno1,Ifi213,Casp1,Dbnl,Dennd1b,Tlr2,Acsl1,Prkar2b,Il10,Gna15,Rnf31,Plscr1,Ccl22,Trim13,Mapkapk2,Tlr6,Lrp8,Mark2,Jun,Nfkbia,Cenpe,Ccl12,Pik3r5,Spry2,Il6,Ccl2,Myc,Adora2b,Cdc42ep4,Map3k8,Ripk2,Psmb6,Pkp4,Il1b,Htr2b,Ralgds,Kitl,Tor1aip1,Fzd5,Pdgfrb,Map2k1,Psd4,Tab2,F11r,Psmb10,Aim2,Apaf1,Pdgfc,Ccl3,Irak3,Sav1,Arhgef3,Ifi209,Stat3,Lpar1,Ifi204,Mtdh,Tlr9,Mmp9,Ptgir,Fam162a,Plekhg1,Cav1,Nos2,Lmo4,Rictor,Egln3,Rap1gap2,Ifi211,Trim14,Kat2b,Cdk5r1,Nr1h3,Cx3cl1,Fas,Sdc4,Pilrb2,Nlrc4,Trip10,Crbn,Gadd45b,S1pr2,Ift57,Gadd45g,Gclm,Mmp14,Nsmaf,Fpr1,Ptafr,Plaur,Tcea1,Elmod2,Thbs1,Bambi,Plk2,Sipa1l1,Rgl1,Csf3,Adora2a,Pdgfb,Inpp5b,Hif1a,Ddx58,Traf1,Trim12c,Malt1,Mdfic,P2ry12,Rgs14,Hspa1a,Cd40,Src,Hsph1,Ccnd1,Psma6,Casp3,Tbc1d1,Adrb2,Mefv,Casp7,Tagap,Cflar,Rgs1,Psmb8,Rabgef1,Sirt1,Casp2,Dcp1a,Rasgrp1,Ifi203,Ccnd2,Arrdc4,Nlrp3,Abr,Atp2b4,Angpt1,Htr2a,Cdc42ep2,Psmd10,Dock4,Map3k6,Flt1,Agrn,Bcl2l11,Nod2,Irf4,Edn1,Prkce |
| 4.456e-22 | -49.16 | GO_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | 131 | 50 | 15632 | 1249 |
Ptpn2,Nlrc5,Syk,Parp9,Ifna5,Ifnb1,Edn1,Stap1,Mul1,Nr1h3,Angpt1,Ifna1,Adar,Cav1,Casp8,Birc3,Rabgef1,Ikbkg,Rnf31,Csf1,Stat1,Socs3,Vrk2,Gfi1,Jak2,Tax1bp1,Traf2,Birc2,Hspa1a,Tnf,Axl,Ifnar1,Rffl,Cd74,Usp18,Stat2,Hif1a,Sphk1,Socs1,Traf1,Ifna2,Irak3,Tnfaip3,Irf7,Ccl5,Tyk2,Ifna6,Ripk2,Il1rn,Irak2 |
| 4.730e-22 | -49.10 | positive regulation of signaling | biological process | GO:0023056 | 1853 | 235 | 20694 | 1406 |
Stau1,Sema4c,Stap1,Edn1,Nod2,Fas,Gadd45g,Ddx60,Nectin2,Ptger4,Adora2a,Hdac1,Phlpp1,Il10,S100a8,Cx3cr1,Map2k4,Plaur,Intu,Acvr1,Marco,Tlr2,Gpr18,Cd300lf,Irak2,Il18,Zc3h12a,Itgal,Gfi1,Notch1,Spred1,Traf2,Irgm2,Tifa,Mul1,Ripk2,Parp9,Wdfy1,Wdr59,Tab2,Casp4,Map4k4,Csf3,Gcnt2,Casp1,Hap1,Ptprj,Igf1r,Cd40,Fgr,Mtdh,Ankrd17,Nlgn2,Map3k6,Phip,Nox1,Irs2,Ifnb1,Nod1,Icam1,Ccl5,Rnf31,Malt1,C3,Cd74,Cd180,Tlr1,Cited2,Syk,Stxbp1,Ccl4,Bambi,Rsad2,Fam162a,Jun,Ccl3,Il1a,Daxx,Mapkbp1,Tnf,Pik3r5,Angpt1,Pml,Ccr1,Atf3,Acpp,Pim2,Rasgrp1,Ago3,Ccl12,Sqstm1,Htr2b,Rims3,Osm,Lyn,Cav1,Clcf1,Ccl22,Sirt1,Mmp9,Axl,Lgals9,Trim13,Hhex,Pik3r6,Dhx58,Atm,Cyfip1,Ksr1,Ptgs2,Cd38,Rapgef2,Plscr1,F10,Adora2b,Spry2,Il15,Hcar2,Csf1,Nupr1,Htr2a,Ccl8,Pde5a,Myc,Pdgfrb,Plagl2,Fzd5,Ptpn2,Ptk2,Nr1h3,Prag1,Kmo,Ccl9,Eef1e1,Mecp2,Ppp2r1b,Cenpj,Rbpms,Glipr2,Map3k8,Eif2ak2,Ccl7,Apaf1,Tlr9,Adrb2,Slc9a1,Ccl2,Parp14,Glrx,Crkl,Zbp1,Sphk1,Tlr6,Jak2,Rictor,Inhba,Tnfaip3,Irf7,Traf5,Ripk3,Cysltr2,Clec4n,Zc3hav1,Rgs14,Akt3,Scimp,Lif,Pdgfb,Flt1,Usp12,Tnfsf15,Lpar1,Ikbke,Nr3c1,Gpr68,Treml4,Stat3,Bcl2l11,Src,Peli1,Fpr2,Map2k1,Hcls1,Notch2,Gdf15,Bnip3,Cd14,Gadd45b,Spred3,Il12b,Il1rn,Cgas,Traf3ip2,Nlrc5,Sik3,Kdr,Kitl,P2ry12,Cacna1d,Mdfic,Cx3cl1,Nck1,Myd88,Serp1,Tnfsf10,Met,Irgm1,Gpr35,Acvrl1,Casp8,Fcgr2b,Tlr3,Ikbkg,Gja1,Nfkb1,Crlf3,Prkce,Tnfsf14,Mlkl,Pdgfc,Pmaip1,Ppp2r3a,Il1b,Il6,Acvr1b,Hif1a,Cflar,Jag1,Mid1,Cacnb3,Thbs1,Plk2,Casp2,Ctsc,Bmp2 |
| 4.935e-22 | -49.06 | GSE22589_HEALTHY_VS_SIV_INFECTED_DC_DN | MSigDB lists | GSE22589_HEALTHY_VS_SIV_INFECTED_DC_DN | 179 | 59 | 15632 | 1249 |
Casp3,Minpp1,Rab11fip1,Dbnl,Ccnd1,Tlk2,Parp8,Dpy19l1,Ddhd1,Gypc,Cst7,Bfar,Mdfic,Psme1,Ch25h,Pml,Cd180,Psmb10,Sap30,Ext1,Wars,Dgka,Junb,Slc7a8,Gch1,Gja1,Asah2,Tap2,Ppm1k,Plcl2,Trafd1,Herc6,Tlr3,Phf6,Slamf8,Il12b,Optn,Samd9l,Nfkbia,Nlrc5,Rbms2,Pfkfb3,Kif9,Trp53i11,Col4a2,Gpc1,Tap1,Slc28a2,Aldh1b1,Ppm1l,Psme2,Hat1,Tor3a,Rnf31,Gbp7,Nos2,Tax1bp1,Endod1,Acsl1 |
| 5.064e-22 | -49.03 | cellular response to biotic stimulus | biological process | GO:0071216 | 288 | 71 | 20694 | 1406 |
Cx3cr1,Il10,Ppp1r15b,Arid5a,Gch1,Ccl12,Tnfsf4,Fcgr2b,Gbp2,Pf4,Nfkbia,Myd88,Ccl2,Cxcl1,Tnf,Syk,Cd180,Il12b,Il1rn,Tlr1,Nr1h3,Pde4b,Fcgr4,Malt1,Fzd5,Zfp36,Cd14,Serpine1,Nod2,Ccl5,Cxcl2,Tnip3,Mtdh,Stap1,Cmpk2,Casp1,Cd86,Nfkbil1,Bcl2l11,Plscr1,Ripk2,Irgm2,Nos2,Il6,Cxcl9,Klrk1,Cd80,Cxcl10,Ptafr,Irf8,Axl,Gfi1,Il1b,Cd274,Nlrp3,Irak2,Zc3h12a,Tnfrsf1b,Il18,Lyn,Tnfaip3,Cxcl3,Nfkb1,Cxcl11,Tlr2,Prkce,Nfkbib,Stat1,Acod1,Tlr6,Jak2 |
| 5.254e-22 | -49.00 | regulation of multicellular organismal development | biological process | GO:2000026 | 2178 | 264 | 20694 | 1406 |
Sipa1l1,Csf3r,Ntng2,Spen,Ifrd1,Klf2,S1pr2,Csf1,Nupr1,Il15,Spry2,Ptpn2,Pdgfrb,Myc,Prkx,Rac3,Kdm5b,Zeb1,Prag1,Clec2d,Dync1i2,Ptk2,Znrf3,Mecp2,Tulp3,Vegfc,Ap3b1,Socs1,Pdpn,Hopx,Eif2ak2,Stat5a,Cxcl1,Glipr2,Ccl2,Slamf8,Nfkbia,Tlr9,Adrb2,Pf4,Sdc2,Flrt3,Stat1,Bcor,Timp1,Errfi1,Sphk1,Rap1gap2,Crkl,Maff,Vasn,Cysltr2,Tnfaip3,Trib1,Inhba,Pgk1,Tnfrsf1b,Nlrp3,Rgs14,Akt3,Flt1,Cxcl10,Mafg,Pdgfb,Lif,Gpc1,Lpar1,Egr3,Src,Stat3,Sema3c,Gpr68,Nr3c1,Eif4g2,Hcls1,Map2k1,Mosmo,Egr1,Srgn,Rgcc,Notch2,Zhx2,Ednrb,Bcl6,Il1rn,Agrn,Il12b,Cnot4,Cst7,Mark2,Dusp6,Kdr,Plaat3,Ubash3b,H2-Aa,Cx3cl1,P2ry2,P2ry12,Kitl,Acvrl1,Met,Nck1,Tmem176a,Etv5,Katna1,Casp8,Gja1,Hk2,Nfkbiz,Tlr3,Ccnd1,Cdk5r1,Keap1,Mdm2,Il1b,Isg15,Ppp2r3a,Hmga2,Fubp1,Itga5,Acvr1b,Hif1a,Il6,Kdm4a,Jag1,Lox,Cflar,Il2rg,Tnfsf9,Plk2,Lhx2,Thbs1,Cd34,Bmp2,Ctsc,Sema4a,Edn1,Stap1,Sema4c,D16Ertd472e,Lrp8,Fas,Serpine1,Tmem176b,Nfkbid,Flrt2,Ctla2a,Zfp36,Irak3,Sav1,Itgb8,Ccr3,Mmp14,Phldb1,Lnpk,Kif3c,Abcb1a,Mov10,Ptger4,Tspo,Ehd1,Irf1,Plau,Phlpp1,Hdac1,Ust,Acvr1,Tnfsf4,Cx3cr1,Il10,Rab21,Foxp4,Pim1,Hmox1,Tlr2,Zc3h12a,Fgl2,Il18,Tomm70a,Scarf1,Notch1,Trip10,Gfi1,Scn1b,Spred1,Tmem178,Mul1,Ripk2,Hlx,Lrp4,Csf3,Gcnt2,Map4k4,Ldlr,Hap1,Jarid2,Wars,Nlgn2,Mycl,Mtdh,Cd40,Igf1r,Ccl5,Ifnb1,Kat2b,Malt1,Sec24b,Oas2,Aida,Parp3,Cd74,C3,Bambi,Syk,Cited2,Pde3b,Zswim4,Tnf,Il1a,Ccl3,Sod2,Tcf4,Jun,Fzd1,Ikzf1,Col4a2,Noct,Prdm1,Il27,Pilrb1,Rasgrp1,Ccr1,Pml,Itpr1,Ptch1,Dbnl,Ahr,Pbx1,Myadm,Clcf1,Cav1,Lyn,Klf7,Kremen1,Il4ra,Mmp9,Sirt1,Fam20c,Pik3r6,Hhex,Cd274,Cd83,Il15ra,Lgals9,Axl,Casz1,Cyfip1,Ptgs2,Mmd,Fos,Rapgef2,Cd38,Cd86,Adgrl2 |
| 5.425e-22 | -48.97 | cellular response to molecule of bacterial origin | biological process | GO:0071219 | 267 | 68 | 20694 | 1406 |
Tnf,Cxcl1,Ccl2,Myd88,Gbp2,Pf4,Nfkbia,Ccl12,Gch1,Arid5a,Fcgr2b,Tnfsf4,Cx3cr1,Il10,Stap1,Mtdh,Cxcl2,Ccl5,Tnip3,Serpine1,Nod2,Fzd5,Malt1,Fcgr4,Zfp36,Cd14,Pde4b,Il1rn,Il12b,Nr1h3,Tlr1,Cd180,Cxcl10,Ptafr,Il6,Cd80,Klrk1,Cxcl9,Nos2,Ripk2,Irgm2,Plscr1,Nfkbil1,Cd86,Cmpk2,Casp1,Jak2,Tlr6,Stat1,Acod1,Nfkbib,Cxcl11,Tlr2,Prkce,Lyn,Tnfaip3,Nfkb1,Cxcl3,Tnfrsf1b,Zc3h12a,Il18,Irak2,Il1b,Nlrp3,Cd274,Gfi1,Irf8,Axl |
| 5.506e-22 | -48.95 | positive regulation of cell motility | biological process | GO:2000147 | 558 | 105 | 20694 | 1406 |
Edn1,Sema4c,Csf1,Dock4,Spry2,Col18a1,Carmil1,Serpine1,Pla2g7,Pdgfrb,Myc,Itga4,Rhoc,Mmp14,Ptk2,Cmklr1,Plpp3,Ptger4,Vegfc,Pdpn,Stat5a,Glipr2,Plau,Ccl2,Acvr1,Tnfsf4,Jak2,Sphk1,Crkl,Hmox1,Tlr2,Swap70,Zc3h12a,Il18,Notch1,Akt3,Sele,Flt1,Cxcl10,Ptafr,Pdgfb,Lpar1,Src,Gcnt2,Stat3,Map4k4,Sema3c,Ptprj,Map2k1,Fpr2,Cxcl14,Fgr,Cd40,Igf1r,Egr1,Ccl5,Icam1,Irs2,Cd74,Kdr,Ccl4,Cx3cl1,Il1a,P2ry2,Jun,Sod2,P2ry12,Kitl,Met,Angpt1,Rras2,Ccl12,Abcc1,Ccr1,Itgav,Tnfsf14,Myadm,Prkce,Nr4a3,Lyn,Sell,Tnfrsf14,Cav1,Pdgfc,Sirt1,Mmp9,Mdm2,Il1b,Cd274,Lgals9,Fubp1,Hif1a,Itga5,Acvr1b,Atm,Ptgs2,Syne2,Rapgef2,Plk2,Thbs1,Pik3cd,Spn,Bmp2,Adora2b,Sema4a |
| 5.597e-22 | -48.93 | GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP | MSigDB lists | GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP | 185 | 60 | 15632 | 1249 |
Cxcl2,Phlda1,Rrs1,Igsf8,Slfn4,Lcp2,Dusp6,Gch1,Slc4a7,Nampt,Hsd17b12,Ccr1,Gng12,Cldnd1,Tnfsf10,Slfn3,Bcl2a1a,Ttc39b,Serpinb9,Tmem229b,Kcna3,Fndc3a,Bcl2a1d,Rsad2,Casp3,Ankrd17,Acpp,Tnf,Ifit1,Daxx,Traf5,Traf1,Nupr1,Pou2f2,Isg20,Csf1,Gem,Il10,Zc3h12c,Pdk3,Idi1,Ldlr,Cd82,Rbms1,Cflar,Ell2,Hmgcs1,Cpd,Ncoa5,Il6,Prkce,Cited2,Bcl2a1b,Ass1,Tle3,Chmp4b,Pnpt1,Slc16a1,Pim3,Ccnd2 |
| 5.597e-22 | -48.93 | GSE24726_WT_VS_E2_22_KO_PDC_DAY4_POST_DELETION_DN | MSigDB lists | GSE24726_WT_VS_E2_22_KO_PDC_DAY4_POST_DELETION_DN | 185 | 60 | 15632 | 1249 |
Magohb,Mcoln2,Traf1,Jmjd6,Agtrap,Cd14,Ube2f,Irak3,Gbp2,Tnfaip3,Hck,Src,Ehd1,Slc16a3,Traf2,Psmb9,Nfkbie,Slc31a1,Parp3,St7,Pcdh7,Cmklr1,Pgk1,Il1b,Ptges,4933430I17Rik,Snx10,Hsd17b12,Map2k1,Irf7,Bst1,Ciapin1,Gmppb,Nr1h3,Pilra,Aoah,Pik3r5,Mrpl52,Mllt6,Dusp4,Dram1,C3,Filip1l,Irf1,Mthfd2,Rab20,Jak2,Fam20c,Agpat4,Lrrc8c,Gsta3,Birc3,Psmb8,Tnfrsf1b,Sema3c,Zc3h12c,Layn,Alas1,Met,Rasgrp1 |
| 6.170e-22 | -48.84 | positive regulation of cellular component movement | biological process | GO:0051272 | 576 | 107 | 20694 | 1406 |
Acvr1,Tnfsf4,Ccl2,Plau,Glipr2,Stat5a,Pdpn,Mecp2,Plpp3,Vegfc,Ptger4,Cmklr1,Ptk2,Mmp14,Rhoc,Itga4,Myc,Pdgfrb,Serpine1,Carmil1,Col18a1,Spry2,Pla2g7,Csf1,Dock4,Edn1,Sema4c,Fpr2,Ptprj,Map2k1,Sema3c,Map4k4,Gcnt2,Stat3,Src,Lpar1,Pdgfb,Cxcl10,Flt1,Ptafr,Akt3,Sele,Notch1,Zc3h12a,Swap70,Il18,Hmox1,Tlr2,Sphk1,Crkl,Jak2,Ccr1,Rras2,Ccl12,Abcc1,Angpt1,Met,Kitl,P2ry12,Jun,Sod2,Cx3cl1,P2ry2,Il1a,Ccl4,Kdr,Cd74,Bcl6,Irs2,Ccl5,Egr1,Icam1,Fgr,Igf1r,Cd40,Cxcl14,Adora2b,Sema4a,Bmp2,Pik3cd,Thbs1,Plk2,Rapgef2,Spn,Syne2,Ptgs2,Atm,Acvr1b,Hif1a,Itga5,Lgals9,Fubp1,Il1b,Cd274,Mdm2,Pdgfc,Sirt1,Mmp9,Lyn,Sell,Cav1,Tnfrsf14,Tnfsf14,Myadm,Nr4a3,Prkce,Itgav |
| 7.933e-22 | -48.59 | IRF_Q6 | MSigDB lists | IRF_Q6 | 221 | 66 | 15632 | 1249 |
Fcgr2b,Bbx,Nod2,Il18bp,Ifnb1,Gsdmd,Casz1,Rbms2,Ciita,Cd80,Adar,Zbp1,Dnase1l3,Ddx60,Bcor,Rtp4,Trim21,Tifa,Atxn7l1,Syne2,Etv6,Psmb8,Mov10,Sik3,Nlgn2,Cpeb4,Casp7,Ifi35,Ptk2,Fut8,Sat1,Ifi44,Slc15a3,Batf2,Tlk2,Ccnd1,Dhx58,Tapbp,Atp13a1,Ehd1,Armcx6,Ifit2,Etv5,Irf2,Isg15,Pigv,Dtx3l,Psmb10,Sell,Socs1,Ube2l6,Ext1,Tnfsf15,Parp12,Dgka,Tor1aip1,Osm,Pdgfrb,Pcdh7,Acsl5,Thbs1,Dio2,Pcgf5,Tmem229b,Cxcl10,Tapbpl |
| 8.003e-22 | -48.58 | cellular response to stimulus | biological process | GO:0051716 | 6702 | 621 | 20694 | 1406 |
Nck1,Ifna6,Agtrap,Gpr35,Acvrl1,Spata13,Casp8,Pikfyve,Rbbp8,Cdkn1a,Ifi207,Abtb2,Abcc1,Uba7,Etv5,Pla2g4a,Cacybp,Bcl2a1b,Srxn1,Sik3,Gm5431,Arhgap26,P2ry12,Inpp5b,P2ry2,Mt2,Ifi214,Bnip3,Ifitm1,Cd14,Ednrb,P2ry13,Il12b,Daam1,Ogfrl1,Clic4,Tmem67,Stxbp3,Tnip3,Cpeb4,Nrp2,Plek,Nmral1,Zbtb5,Casp2,Bmp2,Nfkb2,Dusp1,Acvr1b,G3bp2,Mcm9,Il2rg,Lox,Phgdh,Cnn2,Saa3,Tnfrsf8,Lrrc8c,Mlkl,Btg2,Gpr141,Ifna1,Pmaip1,Trib3,Isg15,Il1b,Tlr3,Nfkbiz,Plat,Ifi205,Ifnar1,Nfkb1,Ppp2r5a,Ppm1l,Cdk5r1,Prkce,Keap1,Evl,Nfkbia,Adrb2,Slamf8,Ccl2,Batf,Birc3,Ifit3,Eef1e1,Azi2,Gm4951,Ifna2,Socs3,Tnc,Rnf34,Stat5a,Ascc3,Map3k8,Eif2ak2,Gpr85,Pnpt1,Socs1,Pdpn,Gm12185,Ccl8,Fzd5,Ptpn2,Pdgfrb,Ptk2,Tle3,Nr1h3,Rac3,Prkx,Fosb,Ch25h,Kdm5b,S1pr2,Dgkh,Hspa2,Spen,Rhoq,Sipa1l1,Dnajb2,Gpr84,Hcar2,Il15,Gsr,Gng11,Csf1,Nupr1,Nr3c1,Bcl2a1a,Bcl2l11,Peli1,Stat2,Snx10,Fpr2,Dock10,Map2k1,Pdk3,Trim12c,Lif,Flt1,Tnfsf15,Asb13,Ifi47,Ifi211,Itga9,Rnf139,Tnfrsf1b,P2ry14,Rgs14,Gramd1a,Akt3,Zc3hav1,Nlrp3,Rab19,Susd6,Sphk1,Errfi1,Lcp2,Jak2,Tlr6,Rictor,Irf7,Tnfaip3,Pgk1,Inhba,Vasn,Traf5,Tyk2,Ddx58,Prdx1,Angpt1,Atf3,Parp10,Asah2,Rras2,Caml,Ccl12,Rasgrp1,Selenow,Cited2,Bambi,Stxbp1,Rcsd1,Jun,Fam162a,Il1a,Daxx,Tnf,Mapkbp1,Plk3,Arid5b,Nqo1,Cd180,Parp3,Il13ra1,Cd40,Gbp8,Mtdh,Irs2,Jmjd6,Kat2b,Slc16a1,Icam1,Spn,Rapgef2,Pik3cd,Plscr1,Ldha,Sde2,Adora2b,Marf1,Cd86,Ppp1r12b,Rap2c,Klf6,Cyfip1,Nfil3,Ralgds,Traf1,Ksr1,Ifit2,Pde7b,Bcl9,Gna15,Ifi213,Ptgs2,Plcl2,Ccl22,Mmp9,Sirt1,Slc2a1,Etv3,Il15ra,Lgals9,Cd274,Sqstm1,Dbnl,Itpr1,Acod1,Osm,Cav1,Cxcl11,Irf1,Il10,Rab21,Asf1a,Cx3cr1,Map2k4,Ppp1r15b,Plpp3,Cmklr1,Gbp7,Hspa1a,Dtx3l,Gclm,Itga4,Lnpep,Sgk3,Ccr3,Casp7,Ptgir,Sav1,Rhoc,Tgtp2,Ogfr,Dnaja1,Trip13,Prkar2b,Gng12,Socs7,Sema4c,Cish,Edn1,Hmga1,Hvcn1,Fas,Esd,Nfkbil1,Casp4,Hivep2,Jarid2,Casp1,Ifi203,Hap1,Ccne1,Dgka,Il18rap,Ldlr,Nek6,Ifna5,Traf2,Ripk2,Mul1,Lrp4,Tifa,Mvp,Il18,Zc3h12a,Gfi1,Prokr1,Nfkbib,Slc31a1,Marco,Sbds,Gpr18,Ift57,Met,Serp1,Myd88,Irgm1,Fcgr2b,Gch1,Arid5a,Ubash3b,Nlrc5,Gbp9,Kdr,Egr2,Pilra,Cacna1d,Kitl,Mdfic,Cx3cl1,Gdf15,Bcl6,Ppp1r15a,Rcan1,Mark2,Il1rn,Cgas,Kdm6b,Rnd1,Fut8,Ube2e2,Vcam1,Eno1,Hmgcs1,Cxcl14,Rapgef5,Calcrl,Notch2,Rgcc,Egr1,Tagap,Rab10,Cacnb3,Grk3,N4bp1,Plk2,Thbs1,Mt1,Fbxo4,Trem1,Prnp,Sema4a,Rel,Gem,Samhd1,9930111J21Rik1,Il6,Itga5,Hif1a,Ccnd2,Cflar,Jag1,Gpr132,Mdm2,Pdgfc,Mapkapk2,Pttg1,Hmga2,Dtx2,Hk2,Rhof,Ikbkg,Casp3,Itgav,Gja1,Relb,Nr4a3,Ccnd1,Pf4,Tlr9,Apaf1,Gbp2,Fcgr1,Slc9a1,Ezr,Stip1,Maml2,Glrx,Scyl2,Ddit4,Vegfc,Tulp3,Phactr4,Mecp2,Iigp1,Cenpj,Znrf3,Cxcl1,Ccl7,Rhou,Htr2a,Myc,Pde5a,Dcp1a,Fcgr4,Olfr56,Zeb1,Ccl9,Klf2,Ifih1,Tgtp1,Pde1b,Birc2,Ccrl2,Csrnp1,Csf3r,Spry2,Dock4,Dennd1b,Tnks1bp1,Sema3c,Gpr68,Src,Hck,Stat3,Ggct,H2-Ab1,Egr3,Tfec,Lcn2,Gbp3,Hcls1,Ak4,Pdgfb,Klrk1,Ero1l,Ebi3,Ptafr,Cxcl10,Lrch1,Lpar1,Piezo1,Ikbke,Optn,Mcm6,Gnb4,Mndal,Crkl,Rin2,Flrt3,Prdx5,Stat1,Cxcl3,Il12rb1,Trib1,Cysltr2,Mcm10,Ripk3,Pik3r5,Col4a2,Rab20,Ccr1,Pml,Zyx,Eya4,Pde3b,Syk,Sh3bp4,Stat4,Ccl4,Fzd1,Sod2,Ifi204,Ccl3,Ift22,Oas2,Pde4b,Rnf31,Fpr1,Junb,Malt1,Actb,Gsdmd,Cd74,C3,Tlr1,Larp1,Igf1r,Map3k6,Fgr,Vrk2,F830016B08Rik,Nox1,Phip,Cdkn2d,Nod1,Srm,Ifnb1,Cxcl2,Ccl5,Cd38,Timeless,Hspa1b,Rab9,Fam129a,Tank,Arhgef3,Adgrl2,Stoml1,Rgs3,Cd80,Atm,Ifit1,Gbp2b,Acsl1,Higd1a,Bcl2a1d,Fos,Abr,Ahrr,Arf4,Ier3,Gpsm2,Irf8,Axl,Trim13,Hp,Hhex,Pik3r6,Rab32,Ptch1,Slc39a4,Htr2b,Kremen1,Slc7a11,Il4ra,Tnip1,Lyn,Clcf1,Sdc1,Ahr,Ifi209,Hdac1,Rgl1,Cdc42ep4,Adgrg6,S100a8,Tnfsf4,Acvr1,Plaur,Hinfp,Nr4a1,Ptger4,Atp2b4,Egln3,Ehd1,Adora2a,Aim2,Irak3,Zfp36,Itgb8,Homer1,Stap1,Flrt2,Nfkbid,Nod2,Adap2,Serpine1,H2-Q7,Lrp8,Igtp,Map4k4,Dyrk2,Icosl,Cdc42ep2,Csf3,Gng4,Gcnt2,Cd69,Asns,Xcr1,Cmpk2,Ass1,Stx11,Nmi,Tlk2,Ptprj,Cxcl9,Ifna4,Sesn3,Irgm2,Ifi208,Parp9,Nos2,Wdr59,Smc5,Gbp4,Cd300lf,Tiparp,Irak2,Itgal,Rgs1,Pid1,Notch1,Rhoh,Gm4841,Flnb,Uaca,Adgre4,Gsta3,Plpp1,Themis2,Tlr2,Hmox1,Clec4d,Clec4e,Rnd3,Pim1 |
| 8.403e-22 | -48.53 | negative regulation of signal transduction | biological process | GO:0009968 | 1163 | 169 | 20694 | 1406 |
Plaur,Acvr1,Ddit4,Glrx,Scyl2,Tnfsf4,Cx3cr1,Parp14,Ezr,Il10,Irf1,Phlpp1,Hdac1,Nfkbia,Tlr9,Adrb2,Pf4,Socs1,Znrf3,Rnf34,Socs3,Phactr4,Tulp3,Atp2b4,Tle3,Ptgir,Mmp14,Sgk3,Ptpn2,Irf4,Irak3,Gclm,Spry2,Serpine1,Nfkbid,Nod2,Stap1,Tsku,Cish,Dusp16,Socs7,Dnaja1,S1pr2,Ptprj,Map2k1,Dyrk2,Src,Bcl2a1a,Smpdl3b,Nfkbil1,Nr3c1,Gpc1,Lpar1,Mul1,Lrp4,Sesn3,Htra1,Spred1,Lif,Rhoh,Notch1,Nlrp3,Pid1,Rgs14,Rgs1,Zc3h12a,Optn,Cd300lf,Adar,Vasn,Hmox1,Trib1,Tnfaip3,Ncoa5,Tlr6,Stat1,Errfi1,Uaca,Eya4,Fcgr2b,Asah2,Atf3,Casp8,Met,Nck1,Bfar,Prdm1,Mapkbp1,Tnf,Cx3cl1,Sod2,Rffl,Fzd1,Bambi,Dusp6,Bcl2a1b,Nlrc5,Sh3bp4,Ubash3b,Pde3b,Il1rn,Gclc,Spred3,Cd74,Rcan1,Bcl6,Pde4b,Rpgrip1l,Dusp4,Gdf15,Aida,Egr1,Pmepa1,Rabgef1,Ccl5,Tnip3,Icam1,Uchl1,Cdkn2d,Phip,Mosmo,Igf1r,Bmp2,Samhd1,Rgs3,Dusp2,Prnp,Plek,Tank,Dusp5,Fam72a,Hsph1,Thbs1,Grk3,Dusp8,Ptgs2,Jag1,Bcl2a1d,Cflar,Higd1a,Dusp1,Hif1a,Il6,Atm,Il1b,Dhx58,Hhex,Ppp2r3a,Hmga2,Grina,Ier3,Mmp9,Sirt1,Mdm2,Plcl2,Myadm,Trim30a,Psmd10,Cav1,Lyn,Chst11,Kremen1,Tnip1,Htr2b,Ptch1,Acod1,Itgav,Itpr1,Ikbkg |
| 1.017e-21 | -48.34 | regulation of nucleobase-containing compound metabolic process | biological process | GO:0019219 | 3343 | 362 | 20694 | 1406 |
Max,Arid5b,Gclc,Parp3,Pou3f1,Dr1,Mycl,Mtdh,Cd40,Rbl1,Icam1,Jmjd6,Kat2b,Ikzf1,Mxd1,Parp10,Sertad3,Taf4b,Atf3,Bambi,Cited2,Tnf,Plk3,Il1a,Daxx,Pcgf5,Jun,Tcf4,Etv3,Sirt1,Acod1,Riox2,Sqstm1,Pbx1,Spire1,Cav1,Klf7,Osm,Plscr1,Dusp5,Hsph1,Tax1bp1,Mier3,Rap2c,Adora2b,Nfxl1,Casz1,Nfil3,Klf6,Ifi213,Bcl9,Ier2,Traf1,Oasl2,Irf4,Dtx3l,Sav1,Med13,Edn1,Resf1,Nsd3,Hmga1,Irf1,Irf2,Cx3cr1,Dach1,Il10,Hspa1a,Cmklr1,Plpp3,Zc3h12a,Il18,Gfi1,Foxp4,Nfkbib,Hivep2,Nfkbil1,Trim26,Smg7,Il18rap,Ifi203,Ccne1,Jarid2,Traf2,Rnf14,Hlx,Ripk2,Znfx1,Ednrb,Tra2a,Ifi214,Carhsp1,Agrn,Brd2,Acvrl1,Nck1,Etv5,Cdkn1a,Phf6,Ifi207,Nampt,Zfp513,Rbbp8,Rfx5,Btg2,Il1b,Trib3,Polr2g,Tet2,Ifnar1,Ifi205,Tlr3,Cdk5r1,Keap1,Oas1g,Nfkb1,Nmral1,Lhx2,Bmp2,Zbtb5,Perm1,Dusp1,Acvr1b,Nfkb2,Tnfrsf8,Ptpn2,Fzd5,Pdgfrb,Cebpd,Etv6,Fosb,Kdm5b,Tle3,Nr1h3,Rhoq,Spen,Ifrd1,Nupr1,Batf,Oas3,Med21,Adrb2,Dcp2,Nfkbia,Mllt6,Rbpms,Plekhn1,Arid4a,Eif2ak2,Slfn1,Plagl1,Pnpt1,Aebp2,Stat5a,Tnfrsf1b,Ifi211,Sp140,Plac8,Nlrp3,Rgs14,Zc3hav1,Jak2,Tlr6,Sphk1,Cdyl2,Tcea1,Ddx58,Dek,Hmgn3,Traf5,Tnfaip3,Irf7,Inhba,Peli1,Nr3c1,Pdk3,Map2k1,Stat2,Oas1a,Lif,Wdr43,Psma6,Malt1,Junb,Rnf31,Oas2,Cd74,Fignl2,Tshz1,Phip,Psip1,Igf1r,Larp1,Trim14,Ifnb1,Nod1,Jdp2,Noct,Prdm1,Eya4,Pim2,Pml,Brwd3,Stat4,Syk,Oasl1,Ifi204,Ccl3,Sod2,Fzd1,Klf3,Ier3,Arf4,Hhex,Trim13,Irf8,Lmo4,Ptch1,Helz2,Ifi209,Ahr,Clcf1,Tnip1,Ncoa7,Cdyl,Cd38,Timeless,Tent4a,Atm,Ahrr,Fos,Zfp36,Irak3,Hivep3,Trim21,Tent2,Lrp8,Radx,Nfkbid,Nod2,Hdac1,Hinfp,Acvr1,Nr4a1,Tnfsf4,Ets2,Mov10,Atp2b4,Aim2,Adora2a,Irak2,Notch1,Pid1,Klf8,Pim1,Tlr2,Hmox1,Csf3,Nmi,Nfkbie,Tnfsf8,Htra1,Nos2,Gbp4,Ifi208,Parp9,Ppp1r15a,Bcl6,Gdf15,Cgas,Txn1,Kdm6b,Dnajb4,Eno1,Kmt5a,Egr1,Rgcc,Zhx2,Notch2,Mafk,Met,Myd88,Zfp281,Arid5a,Fcgr2b,Egr2,Kdr,Nlrc5,Cx3cl1,Mdfic,Cacna1d,Mdm2,Tal2,Hmga2,Pttg1,Mapkapk2,Fubp1,Gja1,Ikbkg,Ccnd1,Psmd10,Nr4a3,Crlf3,Zmynd15,Relb,Prnp,Fbxo4,Prdm9,Rel,Hif1a,Il6,Kdm4a,Mamld1,Jag1,Ciita,Cflar,Sap30,Dcp1a,Plagl2,Myc,Htr2a,Oas1b,Zeb1,Ppp4r2,Csrnp1,Birc2,Klf2,Aff1,Spic,Slc9a1,Pf4,Tlr9,Apaf1,Ddit4,Maml2,Ezr,Cenpj,Mecp2,Hopx,Ell2,Pou2f2,Mndal,Prdx5,Stat1,Bcor,Nlrc4,Hat1,Cd200,Maff,Ripk3,Trib1,Egr3,Src,Stat3,Hck,Hcls1,Tfec,Mafg,Ptafr,Ak4,Pdgfb,Batf2 |
| 1.035e-21 | -48.32 | organelle | cellular component | GO:0043226 | 12021 | 984 | 20747 | 1409 |
Rars,Ripk2,Syk,Caml,Flt1,Zbtb5,Abcc1,Prkx,Slc16a1,Tap1,Adrb2,Pstpip2,Slc25a25,Tpm4,Sipa1l1,Gem,Phf11d,Gbp7,Hmox1,Stat1,Sgk3,Ap3b1,Stat4,Ext1,Pla2g4a,Lrp4,Ptch1,Nfkbie,Med21,Nek6,Procr,Lnpep,Rnaset2b,Grina,Sec24b,Gpd2,Lyn,Daxx,Sdc4,Isg15,Rasgrp1,Crlf3,Mcoln2,Dusp16,Ncoa5,Isg20,Anp32a,Rsbn1,Irgm2,Gpr18,Plekha2,Foxp4,Whamm,Dock10,Gsap,Socs1,Ehd1,Ifi213,St3gal1,Tor3a,Perm1,Psme1,Fzd5,Mitd1,Cacybp,Hat1,Vcam1,Oas1g,Arl4a,Btg2,Tapbp,Kcnj2,Bcl6,Mppe1,Ddx58,Slc30a1,H3f3b,Oas3,Itga5,Cnn3,Trim36,Sinhcaf,Ldha,Dnaja2,Pbx1,Slamf7,Rhoc,Ccne1,Rcn1,Slc15a3,Mtfr2,Cdc42ep2,Rab9,H2-Aa,Nfxl1,Prdm1,Arl5c,S100a8,Spire1,Tmtc2,Ezr,Vezt,Tiparp,Milr1,Nck1,Rab10,Ikbke,Adap2,Mcmbp,Adora2a,Rfx5,Cd274,Agpat4,Trim13,Sass6,Rims3,Kitl,Pgap2,Plekhf2,Etv6,Msr1,Tgs1,Ppp1r12b,Tut7,Kat2b,Mfap3l,Rsad2,Irgm1,Cep85l,Chd9,Nod2,Nfkbia,Dock4,Plekhn1,Rab21,Dmwd,Maff,Nr3c1,Nfkbiz,Ier3,Slfn5,Gpsm2,Asah2,Ifit3b,Asap3,Crbn,P2ry13,Map2k4,Ccnj,Prpf4,Lpar1,Pdk3,Ccl2,Hsd17b7,Mx2,9130023H24Rik,Kif5c,Hdac1,F10,Slc25a12,Tyk2,Rap2c,Traf2,Snx10,Lacc1,Rgs3,Ppfia3,Ociad1,Cycs,Plat,Rnd3,Pgs1,Cnn2,Mecp2,Ifi209,Stoml1,Thbs1,Nfil3,Pdpn,Mov10,Tnks1bp1,Arid5a,Gadd45b,Il15ra,Sema4a,Gadd45g,Rab32,Lipg,Sgcb,Myc,Mtcp1,Phyh,Plod3,Stxbp3,Ifi207,Usb1,Rnf14,Ciapin1,Rhbdf2,Wars,Plod2,Marf1,Grk3,Rhou,Oas2,Casp3,Vcpip1,Nt5c3,Phlda1,Ppp1r15a,Dmxl2,Dcp2,Tle3,Fam111a,Cx3cr1,Flrt3,Psmb6,Ifi214,Mdn1,Fignl2,Klf8,Cdyl2,Junb,Pde4b,Arf4,Trim14,Xrn1,Mark2,Noct,Stap1,Zfp800,Sh3bgrl2,Ifit3,Jmjd6,Mthfd2,Plekha5,Slc16a3,Cd14,Rgcc,Ifi204,Slc29a3,Bcorl1,Gbp9,Znrf1,Samsn1,Acod1,Hmgn3,Atp2b4,Abr,Rab11fip1,Radx,Kmt5a,Gk,Fam20c,Chic2,Kif3c,Tnf,Tnfaip3,Lipe,Nr4a3,Klf7,Mdm2,Gbgt1,Usp12,Atp10a,Rilpl1,Hck,Nfkbib,Itpkc,Shfl,Olr1,Spic,Rel,4930453N24Rik,Stat2,Eif4g2,Stat5a,Phlpp1,Cd164,Ranbp2,Gbp2b,Samd9l,Psmd10,Pnp2,Ptk2,Tor1aip1,Polr2g,Nfkb2,Rcan1,Dach1,Adam19,Fgr,Mtdh,Rnf139,Cacna1d,Dusp4,Atp11a,Tuba4a,Golga3,Hivep2,Ifih1,Ets2,Rnf145,Hsd17b12,Aldh1b1,Notch2,Ptger4,Dram1,Ahrr,Trip10,Nos2,Usp25,Ero1l,Zfp36,Ifi208,Serpinb9,Cers6,Coa5,Ddit4,Lcn2,Ifi203,Vrk2,Pikfyve,H2-Q7,Htr2a,Gm4841,9930111J21Rik1,Dennd6b,Psd,Batf2,Tlk2,Ifi35,Calcrl,Pf4,Mxd1,Carhsp1,Tap2,Cd86,Trim21,Parp10,Themis2,Ell2,Hivep3,Zfp319,Pttg1,Uchl1,St3gal6,Edn1,Dennd2a,Tent2,Plaat3,Rnf114,Dek,Dpy19l1,Cenpe,Palld,Cdkn2d,Hcls1,Ccnd2,Zup1,Serpina3g,Psma6,P2ry2,Ep400,Fndc3a,Mt2,Ahsa1,Myo10,Lad1,Rab19,Bbx,Ubr4,Zc3h12a,Jarid2,Parp14,Acsl5,Oas1b,Ier2,Tpx2,Pik3r5,Pdgfrb,Gfi1,Atf3,Etv3,Psip1,Cd40,Hhex,Spata13,Dhrs9,Socs7,Cdkn1a,Ak4,Sde2,Tal2,Nfkbid,Alas1,Flnb,Hspa1b,Slc39a13,Nes,Pcgf5,Ifitm1,Sbds,Treml4,Psmb10,Dnajb4,Nampt,Irf4,Ubash3b,Slc4a7,Xaf1,Cited2,Tra2a,Irf7,Ddx4,Aim2,Tpst1,Sla,F11r,Extl2,Atp6v1d,Ddx60,Mapkapk2,Osbpl3,Fos,Esd,Gm5431,Pml,Tasor2,Tspo,Lox,Kdm5b,Swap70,Pdgfc,Pou2f2,Casp7,Ccr3,Sele,Cop1,Casp2,Etnk1,Cdyl,Klf2,Uba7,P4ha2,Noc4l,Jun,Cyth3,Zeb1,Ccdc86,Parp12,Ikzf1,H2-Ab1,Phf11a,Fcho2,Ifnar1,Bfar,Dusp1,Phf11b,Kdm6b,Stk40,Nox1,Nmral1,Me1,Nr4a1,Rbms1,Shisa3,Rnf19a,Egr1,Sap30,Egln3,Txnrd1,H2-Eb1,Daam1,Tma16,Zfp40,Tbc1d1,Igf1r,1600014C10Rik,Hsph1,Top3a,Katna1,Wdfy1,Mid1,Sesn3,Mier3,Rbpms,Tdrd7,Uaca,Vasp,Prpf38a,Lrp8,Tent4a,Spen,Plagl1,Stx6,Prdx5,Adar,Flrt2,Mt1,Gpc1,Cdc42ep4,Timeless,Tomm70a,Hk2,Trim30a,Rapgef2,Apba1,Cnot4,Mmp14,Herc6,Itga4,Spred1,Lhx2,Ralgds,Bcl2l11,Morc3,Zhx2,P2ry12,Clcn5,Rabgef1,Kdr,Ncoa7,Dbnl,Carmil1,Sod2,Dusp2,Serp1,Slfn9,Arhgap26,Ap3m2,Micall2,Smc5,Minpp1,Naa25,Hopx,Birc2,Oas1a,Hmga2,Pou3f1,Lap3,Pfkfb3,Pnpt1,Gm4951,Cst7,Tmem178,Cgas,Gja1,Dusp8,Cd74,Zfp513,Kdm4a,Tmem176b,Idi1,H2-Q4,Plac8,Psme2,Bcl9,Irak2,Ktn1,Tlr1,Car13,Ksr1,Plekhg1,Trmt1l,Actb,Mrpl52,Mdfic,Casp8,Sgms2,Fam241a,Slc31a1,Prnp,Eif2ak2,Pmaip1,Ust,Hmga1,St3gal3,Plk2,Plpp3,Rbms2,Tlr9,Hk1,Stat3,Dck,Rbbp8,Ago3,Csrp1,Cav1,Mmd,Atp13a1,Ppm1k,Lnpk,Gpr85,Slc44a1,Cutc,Aftph,Fcgr2b,Mafg,Casz1,Sco1,Pde3b,Mul1,Ifit2,Stau1,Gypc,Trip13,Il1b,Itgav,Tulp3,Phf6,Ift22,Errfi1,Pcx,Tet2,Smg7,Bcl2a1a,Homer1,Zfp945,Sema4c,Nr1h3,Irak3,Ppp2r5a,Trim26,D1Ertd622e,Ric1,Clmp,Crkl,Rnf34,Cd38,Hlx,Ogfr,Zyx,Dst,Hk3,Cep350,Peli1,Ppp4r2,Egr3,Ift57,Nlgn2,Taf4b,Myd88,Piezo1,Itpr1,Mosmo,Fam53c,Eef1e1,Bmp2,Igf2bp2,Mndal,Cmpk2,Cebpd,Gramd1a,Prag1,Higd1a,Txn1,Sp140,Degs2,Filip1l,Rcl1,Kif9,F830016B08Rik,Dr1,Ptpn2,Cdk5r1,Slfn1,Spry2,Slc25a37,Csrnp1,Slc7a5,Trib3,Cnp,Dnase1l3,Chmp4b,Wdr43,Armcx6,Mpp7,Ifi47,Clic4,Rtn2,Rapgef5,Il15,Sirt1,Syne2,Dnaja1,Bnip3,Nlrp3,Eya4,Tlr3,St3gal5,Keap1,G3bp2,Src,Gsr,Dync1h1,Dyrk2,Spn,Prkar2b,Gng12,Parp11,Upp1,Tcf4,Dcp1a,Myo1b,Irf8,Mefv,Phf11c,Abtb2,Tmem123,Maml2,Asf1a,Gdf15,Ikbkg,B4galt4,Atm,Dgkh,Prdx1,Mtus1,Myadm,Dtx2,Vps54,Inpp5b,Triobp,Gtpbp2,Acsl1,Fut8,Sav1,Acpp,Traf5,Tshz1,Evl,Zbp1,Mcm10,Riox2,N4bp1,Rhoq,Il1rn,Arid4a,Lrrc8c,Rgs14,Mmp13,Tgfbi,Rhof,Fscn1,Frmd6,Gmppb,Pim1,Kmo,Nlrc5,Zmynd15,Pmepa1,Usp18,Mgat1,Rtn1,Nfkb1,Usp31,Nupr1,Igtp,Mamld1,Malt1,Htr2b,Sec24a,Atp11b,Apobec3,Slc25a22,Prdm9,Hinfp,Tlr2,Sphk1,Marcks,Rac3,Icosl,Chst11,Serpine1,Max,Ednrb,Rffl,Acp2,Srgn,Mcm6,Tor1aip2,Aebp2,Cd34,Birc3,Slc2a1,Fchsd2,Ptgs2,Slc9a1,Hp,Tnip1,Dnajb2,Ahr,Parp9,Gbp2,Tcea1,Pdlim7,Sqstm1,Ifi211,Ifrd1,Clic5,Mapkbp1,Iigp1,Tmem67,Acp5,Cpeb4,Stxbp1,Dusp14,Slc39a4,Glrx,Akt3,H2-Q6,Slc49a4,Rpgrip1l,Notch1,Slc7a11,Phip,Serpinb6b,Abcc4,Setdb2,Plscr1,Tlr6,Lpcat2,Slc30a4,Hif1a,Smox,Pigv,Dennd1b,Ass1,Slc31a2,Hspa1a,Pkp4,Oasl1,Hilpda,Pdss1,Rnf24,Gcnt2,Med13,Sertad3,Relb,Helz2,Icam1,Armc8,Ifi205,Rnaset2a,Cox18,Nfkbil1,Aoah,Ascc3,Ccnd1,4932438A13Rik,Stard7,Slc48a1,Ppp1r15b,Mthfd1l,Sik3,Slc37a3,Map2k1,Zfp281,Casp1,Cox17,Rnf19b,Rubcnl,Scyl2,P4ha1,Fnbp1l,Optn,Rmdn3,Tgtp1,Tapbpl,Kpna3,Mcm9,Aff1,Glipr2,Zc3hav1,Apaf1,Fam162a,Fosb,B3gnt5,Ccng2,Snx2,Parp3,Rab3ip,Ube2e1,Adhfe1,Plk3,Samhd1,Cenpj,Hap1,Irf2,Psmb8,Jdp2,Cept1,Nsd3,Fubp1,Gbp8,Arrdc4,Bcl2a1d,Il4i1,Fas,Klf3,Met,Rai14,Rap1gap2,Arid5b,Tgtp2,Nmi,Larp1,Tfec,Gsdmd,Phlpp2,Trib1,Fabp7,Dusp5,Klf6,Brd2,Intu,Resf1,Stx11,Sh3bp4,Dse,Batf,Arl5b,Agtrap,Cxcl14,Mvp,Gm12185,Bcl2a1b,Frmd4a,Clcn7,Rbl1,Magohb,Ptges,Yju2,Ldlr,Tmod3,Irf1,Dync1i2,Oasl2,Ankrd17,Lgals9,Psmb9,Ccdc88b,Bcor,Ripk3,Arg2,Wdr59,Rab20,Snn,Cpd,Mafk,Vasn,AA467197,Ctsc,Sp100,Etv5,Ctu1,Mx1,Stip1,Ch25h,Brwd3,Snapc1,Ciita,Fam72a,Trim12c,Nxf1,Dtx3l,Gbp3,Sp110,Tnfrsf1b,Egr2,Prkce,Jak2,Znfx1,Rrbp1,Rrs1,Rnd1,Hspa2,Plagl2,Tab2,Mycl,Marcksl1,Casp4,Gch1 |
| 1.064e-21 | -48.29 | MODULE_46 | MSigDB lists | MODULE_46 | 364 | 88 | 15632 | 1249 |
Bst1,H2-Eb1,Fcgr4,Ccr1,Irf7,Osm,Lcp2,Cxcl1,Il1b,Hp,Il2rg,Il18,Ifi44,Stat3,Klf6,Stat5a,P4ha2,Csf3r,Bcl6,H2-Q6,Cd14,Batf,Aim2,Isg20,Zeb1,Csf1,Gem,Sema3c,Ccl4,Oasl1,C3,Ctsc,S1pr2,Il15,Fas,Cx3cl1,Cdk5r1,Tlr1,Pdgfb,Adora2a,Csf3,Ifit1bl2,Nampt,Cd86,Tnfsf10,Pf4,Il15ra,Oas1g,Cd55,Ptger4,Ptafr,Cxcl10,Tgfbi,C1ra,Cst7,Cd40,Timp1,Psmb9,Cd83,Gbp2,Lif,Mthfr,Mxd1,H2-Q7,Isg15,Fgr,Sell,Il1a,Cd69,Oas1a,Tnfsf14,Irf8,Stat1,Tlr2,Irf1,Il6,Ccl2,Myc,Igsf6,Edn1,Cxcl14,Ccl12,H2-Q4,Ifit1bl1,Cx3cr1,Nfkbia,Ciita,Il4ra |
| 1.093e-21 | -48.27 | NUYTTEN_NIPP1_TARGETS_UP | MSigDB lists | NUYTTEN_NIPP1_TARGETS_UP | 646 | 126 | 15632 | 1249 |
Oas1a,Ube2e2,Ifi203,Procr,Plscr1,Casp4,Birc3,P4ha1,Armc8,Azi2,Endod1,Stat1,Ell2,4932438A13Rik,Samd9l,Znfx1,Jun,Flrt3,Tap1,Ppfibp1,Fbxo4,Pnpt1,Xrn1,Atf3,Egr1,Csf3,Oas2,Hk2,Nmi,Ifi208,Ppm1k,Slc31a2,Vegfc,Bcl2a1a,Serpinb2,Tnfsf10,Ptgs2,Oas1g,Bcl2a1d,Egr2,Slc15a3,Ifi205,Tank,Birc2,Ifi213,Dusp1,Casp1,Sp140,Clcn5,Gbp2,Ddx58,Stat2,Trim12c,Isg15,St3gal6,Pml,Tdrd7,Xaf1,Ifi211,Cnn3,Isg20,Gem,Mndal,Plod2,Ahrr,Pmepa1,Gbp2b,Dnajb4,Ifi204,Dram1,Oasl1,Cept1,Parp9,Pla2g4a,Gclm,Bnip3,Parp14,Ctsc,Eif2ak2,Nr4a1,Bcl2a1b,Ifi207,Zc3hav1,Slfn5,Il15,Col4a2,Rtp4,Mpp7,Ifi214,Ddx60,Slc25a12,Car13,Mmp13,Inhba,Cxcl2,Parp12,Arl5b,Plekha4,Serpine1,Vps54,Epsti1,Cxcl1,Plat,Mitd1,Kitl,Usp42,Nr4a3,Ripk2,Hmox1,Aebp2,Rsad2,Sat1,D1Ertd622e,Batf2,Ifi44,Ifi209,Tcf4,P4ha2,Klf6,Ncoa7,Etv5,Pdgfc,Tnfaip3,Tab2,Ifih1,Pigv |
| 1.146e-21 | -48.22 | GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 943 | 162 | 15632 | 1249 |
Hspa2,Glipr2,Rbpms,Stat3,Traf2,Tnf,Ifna2,Ccl3,Pdgfc,Fabp3,Tab2,Cd74,Fzd1,Inhba,Rapgef2,Pdgfrb,Osm,Map2k1,Fzd5,Ppp1r15a,Lcp2,Gdf15,Ccl5,Dusp6,Plek,Ccr1,Il1b,Htr2b,Gcnt2,Irak2,Kitl,Pilrb1,Il18,Map3k8,Adora2b,Ripk2,Tlr3,Crkl,Gadd45g,Ifna5,Pde5a,Mid1,Ifnb1,S1pr2,Stap1,Sqstm1,Syk,Spn,Eif2ak2,Gadd45b,Cd80,Pilrb2,Sdc4,Il15,Mul1,Tpx2,Cx3cl1,Cdk5r1,Fas,Mmd,Rictor,Csf1,Lmo4,Nos2,Cav1,Pid1,Ikbkg,Tnfrsf1b,Ednrb,Atm,Cdkn1a,Ccl4,Rap2c,Jak2,Lyn,Lpar1,Mmp9,Ptgir,Itga5,C3,Sema4c,Tlr9,Ptk2,Acvrl1,Ccnd1,Acvr1,Dbnl,Cd40,Lrp4,Src,Hsph1,Mdfic,Ripk3,Daxx,Bmp2,Nod1,Sphk1,Fgr,Trim12c,Calcrl,Il1a,Hif1a,Icam1,Lif,Malt1,Adora2a,Csf3,Ifna6,Tnfsf15,Pdgfb,Pik3r6,Txn1,Pf4,Vegfc,Plaur,Thbs1,Fpr1,Ptafr,Il12b,Cxcl10,Pim1,Zc3h12a,Dusp5,Ptger4,Nod2,Ccl2,Il6,Ppp2r5a,Prkce,Edn1,Spry2,Jun,Psmd10,Pik3r5,Ccl12,Cenpe,Flt1,Map3k6,Angpt1,Tnfrsf14,Atp2b4,Mark2,Htr2a,Ifna1,Ccnd2,Ccl22,Lrp8,Tlr6,Mapkapk2,Rasgrp1,Sirt1,Cysltr2,Ksr1,Prkar2b,Kdr,Hcls1,Clcf1,Acsl1,Adrb2,Acvr1b,Socs3,Nox1 |
| 1.220e-21 | -48.16 | GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE | MSigDB lists | GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE | 199 | 62 | 15632 | 1249 |
Psma6,Src,Ifi213,Ifi209,Birc2,Ifi205,Tank,Psmb9,Cd14,Nod1,Myd88,Irak3,Relb,Tnfaip3,Hck,Aim2,Malt1,Psme1,Ifih1,Psmb10,Trim12c,Tab2,Ddx58,Cd180,Ifi208,Tlr1,Irf7,Cd86,Irak2,Ikbke,Psmb6,Ripk2,Tlr3,Clec4d,Prkce,Nod2,Syk,Nfkbia,Nlrc4,Psmd10,Clec4e,Ifi207,Tlr6,Mapkapk2,Ifi214,Psme2,Ifi211,Ifi203,Ikbkg,Nfkb1,Clec4n,Birc3,Psmb8,Mndal,Casp8,Marco,Tnip1,Tlr9,Lyn,Tlr2,Tnip3,Ifi204 |
| 1.340e-21 | -48.06 | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_6H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_6H_UP | 171 | 57 | 15632 | 1249 |
Ptges,Nfkb2,Clec4d,Fpr1,Ptafr,Serpinb9,Ptgs2,Zc3h12a,Traf3ip2,Cd55,Ddit4,Sipa1l1,Samsn1,Nampt,Plagl2,Ripk3,Sla,Cd14,Tnfrsf8,Socs1,Mxd1,Cish,Itgb8,N4bp1,Slc25a37,Ehd1,Lrrc25,Ier3,Lyn,Trib1,Tnip3,Socs3,Sema4c,Plscr1,Ksr1,Gna15,Tnfrsf1b,S100a8,Cdc42ep2,Pfkfb3,Il4ra,Irs2,Etv3,Fpr2,Cdkn2d,Nfkbiz,Dusp4,Cpd,Fcgr2b,Irf4,Ptpn2,Trip10,Nlrc4,Syk,Sod2,Trim36,Plac8 |
| 1.412e-21 | -48.01 | GSE24292_WT_VS_PPARG_KO_MACROPHAGE_UP | MSigDB lists | GSE24292_WT_VS_PPARG_KO_MACROPHAGE_UP | 188 | 60 | 15632 | 1249 |
Slc2a6,Rab10,Maff,Nfkbid,Junb,Pik3r6,Samsn1,Pgk1,Parp3,Ldha,Mob3b,Ak4,Slc39a4,Gsr,Prdx5,C1ra,N4bp1,Abcc5,Eno1,P2ry13,Cd302,Homer1,1600014C10Rik,Batf,Ripk3,Malt1,Marcksl1,Sphk1,Plscr1,Pstpip2,Fabp7,Egln3,Met,Rnf19a,Dcun1d3,Layn,Plekhg1,Tmem123,Gfpt1,Dr1,Nfil3,Stard7,Fam162a,Ptk2,Gpd2,Acsl1,Igsf6,Mmp14,Stard5,Pla2g4a,Ift57,Cept1,Ass1,Aoah,Slc16a1,Cd80,Tnfrsf14,Cdkn2d,Nfkbiz,Fas |
| 1.718e-21 | -47.81 | GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | MSigDB lists | GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 437 | 98 | 15632 | 1249 |
Ifi208,Ifit1bl2,Elmod2,Oas1g,Zc3h12a,Traf3ip2,Larp1,Cd55,Ptafr,Il12b,Ifi213,Birc2,Ifi205,Timp1,Nod1,Hck,Mdfic,Notch1,Pml,Nfkbil1,H2-Q7,Isg15,Trim12c,Stat2,Cd180,Ddx58,Plscr1,Htra1,Ifi203,Leng9,Oas1a,Birc3,P2ry2,Il10,Irf8,Tnip1,Trem1,Stat1,Itpkc,Fam111a,Acvr1b,Bcl2l11,H2-Q4,Ifit1bl1,Jun,Adar,Plau,Tap1,Chmp4b,Trim13,Trim26,Inhba,Il12rb1,Ccl5,Fcgr4,Tap2,Ripk2,Rsad2,Dhx58,Hdac1,Tnf,Ifi209,Ankrd17,Oas3,H2-Q6,Tnfaip3,Stau1,Parp10,Prdm1,Aim2,Slpi,Trim14,Isg20,Trim21,Ifi211,Ednrb,Nos2,Mndal,Cav1,Ccl4,Polr2g,Oasl1,Ifi204,Trib1,Pcx,Ifnb1,Pde5a,Sqstm1,Itgav,Spn,Eif2ak2,Il15,Il27,Zc3hav1,Ifi207,Ddx60,Mul1,Ifi214 |
| 1.738e-21 | -47.80 | GSE45365_NK_CELL_VS_BCELL_UP | MSigDB lists | GSE45365_NK_CELL_VS_BCELL_UP | 183 | 59 | 15632 | 1249 |
Jak2,Arf4,Ldlr,Egr3,Zfp36,Ampd3,Gem,Casp8,S100a8,Birc3,Ppp1r15b,Jdp2,Zc3hav1,Tmtc2,Atf3,Egr1,Ifrd1,Ccl2,Il6,Fos,Dnaja1,Fam43a,Ass1,Dcbld2,Gng12,Ptges,Vcam1,Thbs1,Chic2,Osgin2,Arid5b,Rnf19b,Car13,Nfkbid,Cxcl2,Vasp,Slc7a5,Arl5b,Phlda1,Fosb,Serpine1,Junb,Dusp6,Tnfaip3,Cd83,Crlf3,Icam1,Rnd1,Ch25h,Slc30a4,Ier2,Csrnp1,Lif,Fgl2,Dock10,Mdn1,Slc2a1,Dusp1,Ifnar1 |
| 1.738e-21 | -47.80 | cell death | biological process | GO:0008219 | 895 | 141 | 20694 | 1406 |
Mlkl,Arel1,Ier3,Sirt1,Trib3,Dram1,Pmaip1,Il1b,Acp2,Pim3,Sqstm1,Tlr3,Hk2,Itgav,Itpr1,Gja1,Casp3,Ikbkg,Cav1,4930453N24Rik,Nfkb1,Kremen1,Tnfsf14,Psmd10,Tax1bp1,Spn,Tmem219,Plscr1,Casp2,Ctsc,Atm,Il6,Acvr1b,Rmdn3,Ifit2,Olr1,Bcl2a1d,Traf1,Cflar,Bnip3,Ppp1r15a,Malt1,Gsdmd,Slc4a7,Traf3ip2,Gclc,Gadd45b,Nod1,Cdkn2d,Srgn,Cxcl2,Serpinb9,Ift57,Myd88,Tnfsf10,Cdkn1a,Pml,Ciapin1,Casp8,Tmem123,Asah2,Pim2,Tpx2,Bcl2a1b,Fam162a,Kitl,Rffl,Sod2,Jun,Plk3,Tnf,Il1a,Daxx,Ifi204,Dnase1l3,Zc3h12a,Tnfrsf1b,Il18,Notch1,Uaca,Crkl,Susd6,Prdx5,Jak2,Nlrc4,Cycs,Inhba,Tnfaip3,Pim1,Usp53,Ripk3,Traf5,Hmox1,Casp4,Ggct,Bcl2l11,Phlda1,Dyrk2,Bcl2a1a,Lcn2,Casp1,Ero1l,1600014C10Rik,Nek6,Traf2,Xaf1,Mul1,Ripk2,Tnfsf15,Ikbke,Irak3,Gclm,Myc,Htr2a,Gadd45g,Fzd5,Sav1,Etv6,Casp7,Sp110,Csrnp1,Birc2,Nupr1,Fas,Hcar2,Slc9a1,Phlpp1,Apaf1,Irf1,Plau,Birc3,S100a8,Nr4a1,Ddit4,Map2k4,Xkr8,Ppp2r1b,Rnf34,Egln3,Aim2,Serpina3g |
| 2.045e-21 | -47.64 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | MSigDB lists | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | 287 | 76 | 15632 | 1249 |
Casp3,Rab21,Nr3c1,Ifi44,Dusp8,Rsad2,Klf6,Ifit2,Dusp1,Ifi213,N4bp1,Psmb9,Bcl6,Ifi209,Ifi205,Tnfaip3,Pml,Isg15,Ube2l6,Ifi208,Nmi,Eya4,Oas2,Ifit1bl2,Ccl5,Ppp1r15a,Rrs1,Med21,Irf7,Snapc1,Cxcl1,Sp110,Cd55,Oas1g,Rcan1,Cxcl10,Ifrd1,Mid1,Ifnb1,Ifit1bl1,Eif2ak2,Nfkbia,Rnf114,Ptpn2,Jun,Tiparp,Rras2,Rnd3,Ifi207,Samhd1,Zc3hav1,Tap1,Atf3,Ifi214,Trim21,Isg20,Zeb1,Ifi211,Plscr1,Zfp36,Oas1a,Ifi203,Tdrd7,Ifit3,Mndal,Gem,Ogfr,Rbms1,Ifi35,Casp7,Egr3,Oasl1,Stat1,Ifi204,Map2k4,Ifit3b |
| 2.064e-21 | -47.63 | GSE7852_THYMUS_VS_FAT_TCONV_DN | MSigDB lists | GSE7852_THYMUS_VS_FAT_TCONV_DN | 195 | 61 | 15632 | 1249 |
B3gnt5,Bcl2a1d,Pnp2,Itgb8,H2-Q6,Ttc39c,Cst7,Spryd7,Apobec3,Dpy19l1,Mdfic,Crim1,Cd38,Ube2f,Tab2,H2-Q7,Maff,Phlda1,Igsf8,Fosb,Samsn1,Hopx,Ppp1r15a,Gch1,Myadm,Plek,Slc4a7,Epsti1,Bcl2a1a,Nr4a3,Phf6,Ptger4,Cyfip1,Bcl2a1b,Flt1,Hivep2,Gadd45b,H2-Q4,Atp2b4,Gpc1,Arl4a,Pttg1,Prnp,Tmem176b,Atf3,Nfkbiz,Atxn7l1,Rel,Il10,Tnfsf14,Cav1,Nfil3,Agpat4,Cd82,Ldlr,Notch2,Ier3,Rcn1,Odc1,Kif5c,Mmp9 |
| 2.079e-21 | -47.62 | HALLMARK_IL6_JAK_STAT3_SIGNALING | MSigDB lists | HALLMARK_IL6_JAK_STAT3_SIGNALING | 83 | 39 | 15632 | 1249 |
Cd14,Myd88,Pdgfc,Cd38,Itga4,Fas,Il4ra,Socs1,Stat2,Il6,Stat3,Acvrl1,Pik3r5,Ifnar1,Tnf,Csf3r,Jun,Ptpn2,Pf4,Il1b,Il15ra,Socs3,Hmox1,Stat1,Il13ra1,Ebi3,Il2rg,Map3k8,Tlr2,Cxcl10,Acvr1b,Irf1,Pim1,Csf1,Tyk2,Cxcl2,Il12rb1,Tnfrsf1b,Ccr1 |
| 2.217e-21 | -47.56 | regulation of macromolecule biosynthetic process | biological process | GO:0010556 | 3370 | 363 | 20694 | 1406 |
Cav1,Klf7,Osm,Pbx1,Sqstm1,Acod1,Riox2,Etv3,Sirt1,Bcl9,Ier2,Traf1,Ifi213,Cyfip1,Nfil3,Klf6,Casz1,Nfxl1,Rap2c,Hsph1,Tax1bp1,Spn,Mier3,Plscr1,Dusp5,Irs2,Kat2b,Jmjd6,Icam1,Mycl,Mtdh,Rbl1,Cd40,Igf2bp2,Dr1,Parp3,Pou3f1,Gclc,Max,Arid5b,Pcgf5,Tcf4,Jun,Plk3,Tnf,Daxx,Il1a,Cited2,Bambi,Atf3,Sertad3,Parp10,Taf4b,Mxd1,Il27,Ikzf1,Nfkbib,Foxp4,Gfi1,Ythdf1,Zc3h12a,Il18,Hlx,Ripk2,Znfx1,Rnf14,Traf2,Ifi203,Ccne1,Jarid2,Smg7,Il18rap,Nfkbil1,Trim26,Hivep2,Hmga1,Nsd3,Edn1,Resf1,Sav1,Med13,Dtx3l,Irf4,Plpp3,Hspa1a,Cmklr1,Dach1,Cx3cr1,Il10,Irf2,Ppp1r15b,Map2k4,Klhl25,Irf1,Nfkb1,Cdk5r1,Keap1,Ifi205,Tlr3,Ifnar1,Trib3,Tet2,Polr2g,Il1b,Rfx5,Btg2,Tnfrsf8,Nfkb2,Perm1,Dusp1,Acvr1b,Zbtb5,Bmp2,Lhx2,Cpeb4,Nmral1,Brd2,Agrn,Ifi214,Ednrb,Cacybp,Cdkn1a,Phf6,Ifi207,Nampt,Zfp513,Rbbp8,Etv5,Nck1,Acvrl1,Tnfaip3,Irf7,Inhba,Ddx58,Hmgn3,Traf5,Sphk1,Cdyl2,Tcea1,Tlr6,Jak2,Errfi1,Rgs14,Nlrp3,Ifi211,Plac8,Sp140,Tnfrsf1b,Rnf139,Wdr43,Psma6,Lif,Stat2,Eif4g2,Map2k1,Nr3c1,Peli1,Nupr1,Il15,Spen,Ifrd1,Rhoq,Etv6,Kdm5b,Fosb,Tle3,Nr1h3,Ptpn2,Fzd5,Cebpd,Pdgfrb,Aebp2,Stat5a,Eif2ak2,Plagl1,Slfn1,Plekhn1,Rbpms,Arid4a,Mllt6,Med21,Gtpbp2,Nfkbia,Adrb2,Dcp2,Ccl2,Batf,Ncoa7,Tnip1,Ahr,Ifi209,Helz2,Ptch1,Lmo4,Trim13,Irf8,Hhex,Arf4,Klf3,Fos,Ahrr,Atm,Timeless,Cd38,Cdyl,Fam129a,Ifnb1,Nod1,Jdp2,Trim14,Ankrd17,Psip1,Igf1r,Larp1,Tshz1,Phip,Nox1,Cd74,Tlr1,Rnf31,Malt1,Junb,Sod2,Fzd1,Ccl3,Ifi204,Stat4,Syk,Brwd3,Pml,Ago3,Pim2,Prdm1,Pim1,Hmox1,Tlr2,Klf8,Pid1,Notch1,Irak2,Parp9,Ifi208,Gbp4,Htra1,Nmi,Nfkbie,Tnfsf8,Dyrk2,Icosl,Csf3,Nfkbid,Nod2,Lrp8,Trim21,Xrn1,Hivep3,Irak3,Zfp36,Aim2,Adora2a,Mov10,Ptger4,Atp2b4,Ets2,Hinfp,Acvr1,Nr4a1,Tnfsf4,Hdac1,Crlf3,Zmynd15,Relb,Ccnd1,Psmd10,Nr4a3,Gja1,Itgav,Ikbkg,Pttg1,Mapkapk2,Fubp1,Tal2,Hmga2,Mdm2,Ciita,Cflar,Sap30,Mamld1,Jag1,Il6,Kdm4a,Hif1a,Rel,Thbs1,Prdm9,Prnp,Fbxo4,Notch2,Zhx2,Egr1,Rgcc,Kmt5a,Dnajb4,Eno1,Txn1,Kdm6b,Bcl6,Gdf15,Ppp1r15a,Cacna1d,Cx3cl1,Mdfic,Nlrc5,Kdr,Egr2,Gfpt1,Arid5a,Fcgr2b,Zfp281,Mafk,Met,Serp1,Myd88,Trib1,Cd200,Maff,Ripk3,Hat1,Prdx5,Bcor,Stat1,Nlrc4,Mndal,Pou2f2,Batf2,Pdgfb,Mafg,Ptafr,Tfec,Hcls1,Sec24a,Egr3,Src,Hck,Stat3,Aff1,Klf2,Csrnp1,Birc2,Zeb1,Myc,Dcp1a,Plagl2,Hopx,Ell2,Mecp2,Cenpj,Maml2,Ezr,Slc9a1,Tlr9,Pf4,Spic |
| 2.234e-21 | -47.55 | response to oxygen-containing compound | biological process | GO:1901700 | 1432 | 194 | 20694 | 1406 |
Acp5,Pdgfc,Mdm2,Il1b,Mapkapk2,Trib3,Ifnar1,Itgav,Casp3,Nr4a3,Prkce,Cdk5r1,Nfkb1,Prnp,Mt1,Thbs1,Cpeb4,Il6,Jag1,Cflar,Cd14,Ednrb,Bnip3,Il12b,Kdm6b,Il1rn,Vcam1,Stxbp3,Tnip3,Rab10,Egr1,Calcrl,Myd88,Agtrap,Fcgr2b,Arid5a,Gch1,Casp8,Egr2,Cacybp,P2ry12,Tnfrsf1b,Nlrp3,Gramd1a,Akt3,Lrp11,Stat1,Prdx5,Tlr6,Jak2,Crkl,Sphk1,Ripk3,Cxcl3,Inhba,Tnfaip3,Trib1,Stat3,Src,Peli1,Nr3c1,Pdk3,Stat2,Lcn2,Fpr2,Ptafr,Cxcl10,Klrk1,Pdgfb,Serpina3f,Lpar1,Pdgfrb,Fcgr4,Ptpn2,Htr2a,Nr1h3,Zeb1,Ptk2,Rhoq,Ccl2,Nfkbia,Adrb2,Pf4,Slc9a1,Gbp2,Glrx,Ddit4,Ezr,Mecp2,Ccl7,Eif2ak2,Socs1,Cxcl1,Stat5a,Sirt1,Mmp9,Cd274,Irf8,Axl,Lgals9,Hp,Itpr1,Ptch1,Acod1,Htr2b,Cxcl11,Ahr,Lyn,Sell,Cav1,Plscr1,Cd38,Timeless,Rapgef2,Cd86,Slpi,Cd80,Atm,Cyfip1,Ptgs2,Fos,Abr,Junb,Nqo1,Actb,Malt1,Pde4b,Cd180,Phip,Nox1,Igf1r,Larp1,Pfkl,Mtdh,Icam1,Ccl5,Cxcl2,Kat2b,Irs2,Cdkn2d,Ifnb1,Nod1,Noct,Prdx1,Ccl12,Pde3b,Sh3bp4,Stat4,Tnf,Plk3,Jun,Sod2,Il18,Zc3h12a,Irak2,Notch1,Gfi1,Pid1,Nfkbib,Hmox1,Tlr2,Pim1,Nfkbil1,Casp4,Ldlr,Casp1,Cmpk2,Traf2,Cxcl9,Tab2,Nos2,Irgm2,Sesn3,Ripk2,Zfp36,Irak3,Itga4,Ptgir,Homer1,Stap1,Socs7,Esd,Nod2,Serpine1,Irf1,Gk,Tnfsf4,Ppp1r15b,Nr4a1,Il10,Cx3cr1,Atp2b4,Ptger4,Serpina3g |
| 2.365e-21 | -47.49 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_DN | 184 | 59 | 15632 | 1249 |
Ripk2,Cxcl10,Tmem229b,Mitd1,Ptges,Keap1,Hcar2,Cmpk2,Epsti1,Ccr1,Snx10,Klf2,Cnp,Sap30,Parp12,Rhoh,Mthfr,Irf2,Ch25h,Prdm1,Traf1,Isg15,Spata13,Usp18,Bfar,Sav1,Hck,Gda,Casp1,Plekhf2,Gypc,Oas3,Rgs14,Itpr1,Dbnl,Ccdc86,Glipr2,Mmp9,Slc25a22,Rgs1,Cd300lf,Rap2c,Clcf1,Dach1,Irf8,Tifa,Ccrl2,Stat4,Atf3,Pgs1,Rtp4,Rbm43,Adar,Pfkfb3,Tle3,Dusp2,Katna1,Fcgr2b,Ap3b1 |
| 2.365e-21 | -47.49 | GSE17721_CTRL_VS_LPS_8H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_8H_BMDC_DN | 184 | 59 | 15632 | 1249 |
Mtdh,Ell2,Dusp16,Arf4,Cd82,Sema3c,Irf8,Cep350,Birc3,Tnfrsf1b,Pou2f2,Slpi,Phip,Coa5,Kat2b,Palld,Stxbp1,Hinfp,Col4a2,Nr4a1,Nfkbia,Mllt6,Cpd,Dusp2,Mmp14,Rai14,Arid5b,Map3k8,Hmox1,Pkp4,Serpinb2,Samsn1,Vps54,Jarid2,Rgl1,Tshz1,G3bp2,Tbc1d13,Oas2,Tmeff1,Rilpl1,Socs1,Gbp3,Itga4,Rab3ip,Mdfic,Prpf38a,Traf5,1600014C10Rik,Homer1,Itpr1,Timp1,Psmb9,Tcf4,Stat5a,Ddhd1,Plekhf2,Hdac1,Dhx58 |
| 2.876e-21 | -47.30 | cellular response to interferon-gamma | biological process | GO:0071346 | 100 | 40 | 20694 | 1406 |
Evl,Gbp2,Irf1,Ccl2,Cdc42ep2,Cdc42ep4,H2-Ab1,Rab20,Irgm1,Casp1,Zyx,Stx11,Gbp3,Ccl12,Nmi,Gbp9,Gbp2b,Ccl4,Stxbp1,Gbp7,Ccl7,Ccl3,Gbp4,Cx3cl1,Nos2,Ccl22,Ccl8,Irf8,Il12b,Ccl9,Flnb,Gbp8,Acod1,Stat1,Stxbp3,Jak2,Il12rb1,H2-Q7,Tlr2,Ccl5 |
| 2.965e-21 | -47.27 | HINATA_NFKB_TARGETS_KERATINOCYTE_UP | MSigDB lists | HINATA_NFKB_TARGETS_KERATINOCYTE_UP | 88 | 40 | 15632 | 1249 |
Tnc,Mmp14,Il6,Pdpn,Bcl2a1d,Nfkbia,Tnf,Stat5a,Ccl12,Bcl2a1b,Sod2,Birc2,Plau,Rnd3,Il15,Cd83,Bmp2,Tnfaip3,Tap1,Olr1,Il1a,Icam1,Traf1,Cxcl2,Nfkb1,Ccl5,Slc7a2,Serpine1,Bcl2a1a,Cflar,Il1rn,Plat,Serpinb2,Tnfaip2,Tnip1,Il1b,Cdkn1a,Mmp9,Irf1,Cxcl10 |
| 3.089e-21 | -47.23 | GO_POSITIVE_REGULATION_OF_CELL_COMMUNICATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_COMMUNICATION | 1418 | 214 | 15632 | 1249 |
Trim13,Phip,Ccl22,Mapkapk2,Tlr6,Ccl2,Peli1,Il6,Spry2,Jun,Pik3r5,Ccl12,Hcls1,Kdr,Tlr2,Acvr1b,Socs3,Tnfsf14,Il10,Rnf31,Clec4n,Rhoc,Ripk3,Daxx,Bmp2,Nod1,Sphk1,Intu,Fgr,Icam1,Pml,Hhex,Psme1,Acvrl1,Acvr1,Dbnl,Psmb9,Casp1,Axl,Hcar2,Tnfsf10,Il12b,Ptgs2,Dusp5,Traf3ip2,Ptprj,Larp1,Hap1,Tnfsf15,Pik3r6,Txn1,Il15,F10,Irs2,Mul1,Nck1,Ddx60,Ifnb1,Pde5a,Stap1,Sqstm1,Syk,Eif2ak2,Ccl4,Jak2,Lyn,Itga5,Sema4c,Ptk2,Psme2,Slc9a1,Csf1,Casp8,Nfkb1,Ikbkg,S100a8,Atm,Sla,Traf5,Cd74,Dhx58,Rsad2,Gpr68,Serp1,Traf2,Tnf,Irak2,Tlr3,Crkl,Inhba,Rapgef2,Wdfy1,Ccl5,Gdf15,Dusp6,Angpt1,Tnfrsf14,Htr2a,Atf3,Nod2,Prkce,Edn1,Psmd10,Bcl2l11,Nlrc5,Map3k6,Flt1,Nlgn2,Gfi1,Clcf1,Cflar,Adrb2,Nox1,Eef1e1,Casp2,Rasgrp1,Jag1,Sirt1,Cysltr2,Ksr1,Birc3,Psmb8,Mdfic,Notch1,Crlf3,Trim12c,Cd180,Hif1a,Il1a,Lif,Malt1,Psma6,Birc2,Cd40,Hspa1a,Acpp,Rgs14,Src,Pf4,Plaur,Bambi,Thbs1,Fpr1,Cxcl10,Zc3h12a,Ptger4,Csf3,Wdr59,Pdgfb,Plk2,Zc3hav1,Spred1,Cd80,Mpp7,Nr1h3,Cx3cl1,Nek6,Fas,Gadd45g,Mid1,S1pr2,Ctsc,Bnip3,Ptpn2,Cited2,Gadd45b,Fam162a,Ppp2r1b,Notch2,Lpar1,Mmp9,Ptgir,Pim2,C3,Mtdh,Tlr9,Rictor,Cav1,Rel,Tnfrsf1b,Ccl3,Plagl2,Pdgfc,Apaf1,Cd38,Myd88,Psmb10,Tab2,Glipr2,Mecp2,Rbpms,Stat3,Ankrd17,Homer1,Il1b,Htr2b,Ikbke,Gcnt2,Kitl,Map3k8,Il18,Adora2b,Hmox1,Psmb6,Ripk2,Ppp2r3a,Pdgfrb,Map2k1,Irf7,Osm,Fzd5,Gja1,H2-Eb1,Ccr1 |
| 3.255e-21 | -47.17 | GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_UP | MSigDB lists | GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_UP | 131 | 49 | 15632 | 1249 |
Slc25a25,Sdc4,Htr2a,Atf3,Nfkbiz,Egr1,Lrp8,Irs2,Spry2,Edn1,Il6,Dusp4,Nr4a1,Ccl12,Fos,Tnfaip2,Nfil3,Egr3,Sema4c,Dnajb4,Odc1,Ier3,Procr,Zfp36,Ccrl2,Kctd12,Rel,Tnfaip3,Plk3,Ier2,Lif,Dusp8,Egr2,Cebpd,Homer1,Cxcl1,Kdm6b,Dusp5,Ptgs2,Nr4a3,Gpr132,Btg2,Phlda1,Maff,Igsf9,Plk2,Ppp1r15a,Serpine1,Fosb |
| 3.557e-21 | -47.09 | positive regulation of leukocyte activation | biological process | GO:0002696 | 312 | 73 | 20694 | 1406 |
Bcl6,Malt1,Ccdc88b,Mmp14,Cd74,Il12b,Nectin2,Fgr,Cd40,Stap1,Vcam1,Nod2,Irs2,Nfkbid,Ccl5,Il15,Nck1,Tlr9,Prdm1,Ccl2,Irf1,Myd88,Ikzf1,Cdkn1a,Il10,Rasgrp1,Tnfsf4,Syk,H2-Aa,Stxbp1,Bst1,Stat5a,Ap3b1,Socs1,Itgal,Il18,Lgals9,Il15ra,Axl,Il1b,Pik3r6,Cd274,Cd83,Nlrp3,Nfkbiz,Tlr6,Tnfrsf14,Cav1,Il12rb1,Il4ra,Tnfsf14,Clcf1,Nr4a3,Clec4d,Thbs1,Cd38,Hsph1,Spn,Peli1,H2-Ab1,Egr3,Tnfsf9,Icosl,Adora2b,Ctsc,Cd86,Il6,Klrk1,Cd80,Ptafr,Hlx,Ripk2,Il2rg |
| 3.770e-21 | -47.03 | GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | 239 | 68 | 15632 | 1249 |
Psma6,Ifi213,Src,Psmb9,Tank,Ifi205,Birc2,Ifi209,Myd88,Nod1,Cd14,Hck,Tnfaip3,Relb,Irak3,Malt1,Psme1,Aim2,Ddx58,Cd180,Tab2,Trim12c,Psmb10,Ifih1,Tlr1,Ifi208,Ccl5,Cd86,Irf7,Ikbke,Irak2,Tlr3,Ripk2,Psmb6,Il12b,Clec4d,Prkce,Nod2,Ifnb1,Nfkbia,Nlrc5,Syk,Nlrc4,Psmd10,Clec4e,Ifi207,Tlr6,Mapkapk2,Ifi214,Ifi211,Psme2,Plscr1,Rasgrp1,Ifi203,Psmb8,Clec4n,Birc3,Ikbkg,Nfkb1,Marco,Casp8,Mndal,Tnip1,Tlr9,Tnip3,Ifi204,Tlr2,Lyn |
| 4.185e-21 | -46.92 | positive regulation of locomotion | biological process | GO:0040017 | 590 | 107 | 20694 | 1406 |
Il1b,Cd274,Lgals9,Fubp1,Pdgfc,Sirt1,Mmp9,Mdm2,Myadm,Tnfsf14,Nr4a3,Prkce,Tnfrsf14,Sell,Cav1,Lyn,Pcx,Itgav,Bmp2,Adora2b,Sema4a,Pik3cd,Thbs1,Plk2,Rapgef2,Spn,Ptgs2,Syne2,Hif1a,Acvr1b,Itga5,Atm,Cd74,Ccl5,Egr1,Icam1,Irs2,Cxcl14,Fgr,Igf1r,Cd40,Ccl12,Rras2,Abcc1,Ccr1,Angpt1,Met,Cx3cl1,P2ry2,Il1a,Kitl,Jun,P2ry12,Sod2,Ccl4,Kdr,Chmp4b,Notch1,Akt3,Sele,Swap70,Zc3h12a,Il18,Tlr2,Hmox1,Jak2,Sphk1,Crkl,Ptprj,Map2k1,Fpr2,Gcnt2,Stat3,Src,Sema3c,Map4k4,Lpar1,Cxcl10,Flt1,Ptafr,Pdgfb,Rhoc,Ptk2,Mmp14,Pdgfrb,Myc,Itga4,Csf1,Dock4,Serpine1,Carmil1,Col18a1,Spry2,Pla2g7,Edn1,Sema4c,Acvr1,Tnfsf4,Ccl2,Plau,Pdpn,Glipr2,Stat5a,Cmklr1,Plpp3,Vegfc,Ptger4 |
| 4.977e-21 | -46.75 | GHANDHI_DIRECT_IRRADIATION_UP | MSigDB lists | GHANDHI_DIRECT_IRRADIATION_UP | 89 | 40 | 15632 | 1249 |
Osbpl3,Bcl2a1a,Plcl2,Cxcl1,Serpinb2,Il1b,Cdkn1a,Smc5,Ptgs2,Frmd4a,Inhba,Cxcl2,Birc3,Nampt,Gdf15,Gch1,Zc3h12c,Ascc3,Bmp2,Relb,Tnfaip3,Prdm1,Fas,Plk3,Nfkbiz,Lrp8,Lif,Icam1,Il1a,Slc30a1,Il6,Dusp2,Mdm2,Bcl2a1d,Gpr68,Slc16a3,Sod2,Bcl2a1b,Ppp6r1,Slc7a11 |
| 5.050e-21 | -46.73 | positive regulation of hemopoiesis | biological process | GO:1903708 | 208 | 58 | 20694 | 1406 |
Malt1,Bcl6,Il12b,Cd74,Mmp14,Ccl5,Csf1,Il15,Notch2,Nfkbid,Ikzf1,Irf1,Prdm1,Pf4,Rasgrp1,Tnfsf4,Casp8,Ccr1,H2-Aa,Syk,Socs1,Ap3b1,Tnf,Ccl3,Jun,Kitl,Cxcl1,Stat5a,Il18,Il1b,Pik3r6,Nlrp3,Cd83,Isg15,Il15ra,Lgals9,Axl,Stat1,Nfkbiz,Trib1,Inhba,Il4ra,Tnfsf9,Egr3,Csf3,Stat3,Gpr68,Hcls1,Flt1,Hif1a,Acvr1b,Il6,Lif,Jag1,Hlx,Ripk2,Il2rg,Fos |
| 5.420e-21 | -46.66 | regulation of hemopoiesis | biological process | GO:1903706 | 407 | 85 | 20694 | 1406 |
Il18,Fgl2,Zc3h12a,Isg15,Cd83,Nlrp3,Notch1,Pik3r6,Il1b,Axl,Lgals9,Il15ra,Stat1,Nfkbiz,Pim1,Il4ra,Inhba,Lyn,Trib1,Csf3,Stat3,Egr3,Tnfsf9,Gpr68,Hcls1,Acvr1b,Hif1a,Flt1,Tmem178,Lif,Il6,Jag1,Lox,Fos,Il2rg,Hlx,Ripk2,Zfp36,Ptpn2,Malt1,Ctla2a,Myc,Bcl6,Cnot4,Clec2d,Il12b,Zeb1,Cd74,Mmp14,Csf3r,Fas,Il15,Ccl5,Csf1,Nfkbid,Ifnb1,Tmem176b,Notch2,Irf1,Ikzf1,Pf4,Tlr9,Nfkbia,Il27,Pilrb1,Tmem176a,Prdm1,Slamf8,Tnfsf4,Rasgrp1,Ccr1,Casp8,Kdr,H2-Aa,Syk,Ubash3b,Ccl3,Eif2ak2,Tnf,Ap3b1,Socs1,Stat5a,Cxcl1,Kitl,Jun |
| 5.871e-21 | -46.58 | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_DN | MSigDB lists | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_DN | 187 | 59 | 15632 | 1249 |
Tab2,Calcrl,Ch25h,Mvp,Gda,Sav1,Tank,Klhl25,Casp1,Phldb1,Parp8,Glipr2,Oaf,Cdc42ep4,Ptger4,Ptges,Il1b,Plaur,Cldnd1,Ikbke,Cxcl1,Myo1b,Gdf15,Pde4b,Tbc1d13,Vasp,Dgka,Inhba,Vasn,Phlda1,Stxbp3,Rab10,Nlrp3,Nxf1,Cyth3,Nck1,Pim3,Rnd3,Dnaja1,Trip10,Tagln,Trmt1l,Slc44a1,Igsf6,Il4i1,Mmp14,Lyn,Lpar1,Cd200,Rap2c,Ldlr,Actb,Znrf1,Lcn2,Casp4,Egln3,Ccrl2,Atxn7l1,Trip13 |
| 7.047e-21 | -46.40 | GO_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA | MSigDB lists | GO_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA | 113 | 45 | 15632 | 1249 |
Ccl5,H2-Eb1,Irf7,Nos2,Irf8,H2-Aa,Trim21,Trim26,Oas2,Oas1a,Il12rb1,Oasl1,Stat1,Oas1g,H2-Ab1,Tlr3,Il12b,Ptafr,Irf1,Ccl4,Vcam1,Jak2,Ccl12,Ass1,H2-Q4,Oas3,H2-Q6,Gbp4,Gbp9,Ccl2,Edn1,Irf4,Mid1,Pml,H2-Q7,Irf2,Trim12c,Cx3cl1,Icam1,Ccl22,Fcgr1,Ciita,Ccl3,Hck,Gbp2 |
| 7.294e-21 | -46.37 | RPS14_DN.V1_UP | MSigDB lists | RPS14_DN.V1_UP | 182 | 58 | 15632 | 1249 |
Egr3,Ifi204,Ms4a6d,Tnfaip2,Cdkn1a,Gfi1,Birc3,Itgal,Pid1,Mndal,Ifi211,Jag1,Pla2g7,Ifi203,Cd69,Kctd12,Ifi214,Dmxl2,P2ry14,Pilra,Sdc4,Plau,Ifi207,Trim36,Ccl12,Bcl2a1b,Igsf6,Rin2,Ptger4,H2-Ab1,Clec5a,Slamf8,Tgfbi,Nr4a3,Bcl2a1a,Tfec,Il1b,Slc31a2,Rgl1,Gdf15,Gja1,Plk2,Ifi208,Bst1,Kmo,St3gal6,Cd14,Crim1,Mdfic,Hck,Ifi213,Casp1,Arhgef3,Ifi205,Ifi209,Bcl6,Ly75,Bcl2a1d |
| 7.302e-21 | -46.37 | HUANG_DASATINIB_RESISTANCE_UP | MSigDB lists | HUANG_DASATINIB_RESISTANCE_UP | 81 | 38 | 15632 | 1249 |
Jag1,Ifi203,Kctd12,Met,Ifi211,Ext1,Ifi208,Ifit3,Cav1,Layn,Mndal,Psmb8,Il15ra,Gng12,Dcbld2,Pcdh7,Gbp2b,Inpp1,Ifi204,Tgfbi,Ifit3b,Lyn,Itga5,Ell2,Samd9l,Rai14,Psmb9,Ifi205,Zyx,Ifi209,Ifi213,Ifi207,Pdgfc,Myo10,Plau,Prnp,Upp1,Ifi214 |
| 7.309e-21 | -46.37 | GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_UP | MSigDB lists | GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_UP | 128 | 48 | 15632 | 1249 |
Col4a2,Rnd3,Slc25a25,Atf3,Egr1,Edn1,Spry2,Nod2,Nr4a1,Ccl12,Fos,Jun,Hmga1,Ust,Rgs1,Sema4c,Egr3,Itga5,Trib1,Ier3,Zfp36,Ccrl2,Birc3,Bmp2,Ier2,Il1a,Egr2,Dusp8,Sele,Cebpd,Dusp1,Itpr1,Gtpbp2,Kdm6b,Dusp5,Ptgs2,Rcan1,Adora2b,Nr4a3,Btg2,Phlda1,Maff,Junb,Dusp6,Plk2,Ppp1r15a,Serpine1,Fosb |
| 9.873e-21 | -46.06 | GSE17721_12H_VS_24H_POLYIC_BMDC_UP | MSigDB lists | GSE17721_12H_VS_24H_POLYIC_BMDC_UP | 183 | 58 | 15632 | 1249 |
Jarid2,Slc12a9,Igsf9,Csrp1,Asns,Nrp2,Phlda1,Prdm9,Ripk2,Psmb6,Clec5a,Cox18,Cxcl1,Dek,Nfkb2,Slfn9,Dcbld2,Il15ra,Tfec,Ptges,Ppp2r2a,Stat5a,Src,Casp1,Spryd7,Acpp,Tcf4,Tpst1,Cd302,Minpp1,Cish,Rab9,Usp18,Traf5,Hvcn1,Myo10,Hdc,Bcl9,Met,Rcn1,Rab20,Slc25a22,Tnip1,Lrrc8c,Ap3m2,Gadd45b,Morc3,Pla2g4a,Slfn8,Ctsc,Igsf6,Il6,Stard5,Nck1,Stxbp1,Pnpt1,Aff1,Dusp14 |
| 1.009e-20 | -46.04 | regulation of RNA metabolic process | biological process | GO:0051252 | 3107 | 339 | 20694 | 1406 |
Tnf,Plk3,Oasl1,Daxx,Il1a,Ifi204,Ccl3,Jun,Pcgf5,Sod2,Tcf4,Fzd1,Bambi,Stat4,Cited2,Syk,Taf4b,Parp10,Sertad3,Pim2,Atf3,Brwd3,Pml,Ikzf1,Noct,Mxd1,Prdm1,Trim14,Icam1,Nod1,Ifnb1,Jdp2,Kat2b,Jmjd6,Tshz1,Phip,Dr1,Mycl,Mtdh,Rbl1,Cd40,Psip1,Igf1r,Larp1,Gclc,Cd74,Pou3f1,Malt1,Junb,Rnf31,Max,Oas2,Arid5b,Ifi213,Ahrr,Bcl9,Ier2,Traf1,Oasl2,Fos,Casz1,Nfil3,Atm,Tent4a,Klf6,Rap2c,Nfxl1,Plscr1,Cdyl,Dusp5,Hsph1,Timeless,Tax1bp1,Cd38,Mier3,Ifi209,Ahr,Pbx1,Cav1,Klf7,Osm,Tnip1,Ncoa7,Lmo4,Ptch1,Acod1,Riox2,Sqstm1,Helz2,Hhex,Trim13,Irf8,Etv3,Klf3,Sirt1,Arf4,Aim2,Adora2a,Ets2,Hspa1a,Cmklr1,Plpp3,Mov10,Atp2b4,Irf2,Hinfp,Acvr1,Nr4a1,Tnfsf4,Cx3cr1,Dach1,Il10,Irf1,Hdac1,Lrp8,Nsd3,Nfkbid,Nod2,Hmga1,Edn1,Trim21,Resf1,Tent2,Sav1,Med13,Hivep3,Irf4,Zfp36,Dtx3l,Irak3,Gbp4,Rnf14,Ifi208,Hlx,Ripk2,Parp9,Znfx1,Traf2,Htra1,Nmi,Nfkbie,Tnfsf8,Il18rap,Ifi203,Ccne1,Jarid2,Csf3,Hivep2,Trim26,Nfkbil1,Pim1,Tlr2,Hmox1,Klf8,Foxp4,Nfkbib,Notch1,Pid1,Gfi1,Zc3h12a,Il18,Irak2,Cx3cl1,Mdfic,Cacna1d,Egr2,Kdr,Nlrc5,Etv5,Arid5a,Fcgr2b,Phf6,Ifi207,Nampt,Zfp513,Rbbp8,Mafk,Acvrl1,Met,Myd88,Nck1,Zfp281,Egr1,Rgcc,Zhx2,Notch2,Dnajb4,Brd2,Eno1,Kmt5a,Kdm6b,Txn1,Agrn,Ppp1r15a,Ednrb,Tra2a,Bcl6,Gdf15,Ifi214,Carhsp1,Tnfrsf8,Mamld1,Jag1,Ciita,Cflar,Sap30,Perm1,Hif1a,Acvr1b,Il6,Nfkb2,Kdm4a,Bmp2,Rel,Zbtb5,Prnp,Nmral1,Lhx2,Prdm9,Ccnd1,Psmd10,Cdk5r1,Nr4a3,Keap1,Crlf3,Zmynd15,Nfkb1,Oas1g,Relb,Ikbkg,Ifnar1,Ifi205,Tlr3,Il1b,Tal2,Hmga2,Pttg1,Trib3,Mapkapk2,Fubp1,Polr2g,Tet2,Rfx5,Mdm2,Btg2,Ell2,Hopx,Eif2ak2,Slfn1,Plagl1,Pnpt1,Aebp2,Stat5a,Plekhn1,Rbpms,Arid4a,Cenpj,Mecp2,Maml2,Ezr,Mllt6,Spic,Oas3,Batf,Med21,Slc9a1,Tlr9,Adrb2,Nfkbia,Pf4,Dcp2,Aff1,Nupr1,Csrnp1,Birc2,Rhoq,Spen,Ifrd1,Klf2,Etv6,Fosb,Kdm5b,Zeb1,Oas1b,Tle3,Nr1h3,Fzd5,Ptpn2,Dcp1a,Cebpd,Plagl2,Myc,Batf2,Wdr43,Psma6,Oas1a,Mafg,Ptafr,Pdgfb,Lif,Hcls1,Map2k1,Tfec,Stat2,Peli1,Egr3,Src,Hck,Stat3,Nr3c1,Cd200,Ddx58,Maff,Traf5,Ripk3,Hmgn3,Tnfaip3,Irf7,Trib1,Inhba,Tlr6,Jak2,Prdx5,Bcor,Stat1,Nlrc4,Sphk1,Hat1,Cdyl2,Tcea1,Mndal,Nlrp3,Rgs14,Zc3hav1,Tnfrsf1b,Ifi211,Sp140,Plac8,Pou2f2 |
| 1.069e-20 | -45.98 | cytokine receptor binding | molecular function | GO:0005126 | 327 | 75 | 20217 | 1400 |
Il15,Cd300lf,Tnfsf8,Jak2,Tlr9,Il12b,Csf3,Tnfsf9,Nsmaf,Cxcl14,Cxcl3,Ccrl2,Ccl5,Nes,Ccl22,Angpt1,Cxcl10,Stap1,Il6,Ifna4,Traf1,Stat1,Cxcl1,Ifna1,Syk,Tnf,Ifna5,Stat3,Ifna2,Spred1,Casp3,Cxcl11,Cx3cl1,Il27,Inhba,Pf4,Ccl4,Lif,Cxcl2,Cxcl9,Il10,Clcf1,Ccl12,Gdf15,Tnfsf10,Osm,Il1rn,Il1a,Il1b,Ifna6,Tnfsf4,Kitl,Traf2,Tyk2,Bmp2,Csf1,Lyn,Ccl3,Il12rb1,Cflar,Ccl9,Ccl7,Ebi3,Myd88,Hsd17b7,Tnfsf15,Ccl2,Casp8,Ccl8,Tnfsf14,Spred3,Vegfc,Il18,Ifnb1,Traf5 |
| 1.079e-20 | -45.98 | regulation of RNA biosynthetic process | biological process | GO:2001141 | 2868 | 319 | 20694 | 1406 |
Ptch1,Lmo4,Acod1,Riox2,Sqstm1,Helz2,Ahr,Pbx1,Ifi209,Cav1,Klf7,Osm,Ncoa7,Tnip1,Etv3,Klf3,Sirt1,Arf4,Hhex,Trim13,Irf8,Casz1,Nfil3,Atm,Klf6,Ahrr,Ifi213,Bcl9,Ier2,Traf1,Fos,Plscr1,Dusp5,Cdyl,Hsph1,Timeless,Cd38,Tax1bp1,Mier3,Rap2c,Nfxl1,Tshz1,Phip,Dr1,Mycl,Mtdh,Cd40,Psip1,Rbl1,Igf1r,Trim14,Icam1,Nod1,Ifnb1,Kat2b,Jdp2,Jmjd6,Malt1,Junb,Max,Rnf31,Arid5b,Gclc,Pou3f1,Cd74,Bambi,Stat4,Syk,Cited2,Tnf,Plk3,Daxx,Il1a,Ifi204,Ccl3,Jun,Tcf4,Sod2,Pcgf5,Fzd1,Ikzf1,Mxd1,Prdm1,Taf4b,Parp10,Sertad3,Pim2,Atf3,Brwd3,Pml,Foxp4,Klf8,Nfkbib,Pim1,Tlr2,Hmox1,Zc3h12a,Il18,Irak2,Notch1,Pid1,Gfi1,Traf2,Htra1,Rnf14,Gbp4,Ifi208,Hlx,Parp9,Ripk2,Znfx1,Hivep2,Csf3,Trim26,Nfkbil1,Nmi,Nfkbie,Tnfsf8,Il18rap,Ifi203,Ccne1,Jarid2,Edn1,Trim21,Resf1,Lrp8,Nsd3,Nfkbid,Hmga1,Nod2,Irf4,Zfp36,Dtx3l,Irak3,Sav1,Hivep3,Med13,Ets2,Hspa1a,Cmklr1,Plpp3,Atp2b4,Aim2,Adora2a,Irf1,Hdac1,Hinfp,Acvr1,Irf2,Nr4a1,Tnfsf4,Dach1,Cx3cr1,Il10,Ikbkg,Ifnar1,Ifi205,Tlr3,Ccnd1,Psmd10,Cdk5r1,Nr4a3,Keap1,Crlf3,Zmynd15,Nfkb1,Relb,Mdm2,Rfx5,Btg2,Il1b,Tal2,Hmga2,Pttg1,Trib3,Fubp1,Tet2,Perm1,Acvr1b,Hif1a,Il6,Nfkb2,Kdm4a,Tnfrsf8,Mamld1,Jag1,Ciita,Cflar,Sap30,Prnp,Nmral1,Lhx2,Prdm9,Bmp2,Rel,Zbtb5,Dnajb4,Brd2,Eno1,Kmt5a,Egr1,Rgcc,Notch2,Zhx2,Ppp1r15a,Ednrb,Bcl6,Ifi214,Gdf15,Kdm6b,Txn1,Agrn,Egr2,Kdr,Nlrc5,Cx3cl1,Mdfic,Cacna1d,Mafk,Acvrl1,Met,Myd88,Nck1,Zfp281,Etv5,Arid5a,Fcgr2b,Phf6,Ifi207,Nampt,Zfp513,Rbbp8,Jak2,Tlr6,Prdx5,Bcor,Stat1,Nlrc4,Hat1,Sphk1,Cdyl2,Tcea1,Cd200,Ddx58,Maff,Ripk3,Traf5,Hmgn3,Tnfaip3,Irf7,Trib1,Inhba,Tnfrsf1b,Ifi211,Plac8,Sp140,Pou2f2,Mndal,Nlrp3,Rgs14,Mafg,Ptafr,Pdgfb,Lif,Wdr43,Batf2,Psma6,Peli1,Egr3,Src,Stat3,Hck,Nr3c1,Hcls1,Map2k1,Stat2,Tfec,Csrnp1,Birc2,Rhoq,Spen,Klf2,Ifrd1,Aff1,Nupr1,Fzd5,Ptpn2,Cebpd,Plagl2,Dcp1a,Myc,Fosb,Zeb1,Etv6,Kdm5b,Tle3,Nr1h3,Rbpms,Arid4a,Cenpj,Mecp2,Ell2,Hopx,Slfn1,Plagl1,Eif2ak2,Aebp2,Stat5a,Spic,Batf,Med21,Slc9a1,Tlr9,Nfkbia,Pf4,Adrb2,Maml2,Ezr,Mllt6 |
| 1.140e-20 | -45.92 | negative regulation of metabolic process | biological process | GO:0009892 | 2869 | 319 | 20694 | 1406 |
Ets2,Hspa1a,Mov10,Ptger4,Atp2b4,Plpp3,Adora2a,Serpina3g,Tspo,Irf1,Phlpp1,Hdac1,Tnfsf4,Hinfp,Plaur,Ppp1r15b,Nr4a1,Il10,Dach1,Xrn1,Serpinb2,Edn1,Stap1,Trim21,Dnaja1,Prkar2b,Tent2,Nsd3,Radx,Serpine1,Zfp36,Ctla2a,Lnpep,Gadd45g,Irak3,Dtx3l,Svbp,Itgb8,Spred1,Usp25,Serpinb6b,Mvp,Nos2,Gbp4,Znfx1,Parp9,Ifi208,Tut7,Nfkbie,Nmi,Tlk2,Ldlr,Smg7,Ptprj,Jarid2,Hap1,Ifi203,Ccne1,Foxp4,Klf8,Hmox1,Il18,Zc3h12a,Tiparp,Notch1,Chmp4b,Rhoh,Serpinb9b,Gfi1,Pid1,Cited2,Pde3b,Ric1,Ifi204,Daxx,Tnf,Plk3,Fzd1,Tcf4,Jun,Ikzf1,Angpt1,Noct,Prdm1,Mxd1,Parp10,Caml,Ago3,Ccr1,Pml,Atf3,Dr1,Msr1,Wars,Rbl1,Larp1,Igf1r,Mtdh,Serpinb9,Rabgef1,Cdkn2d,Jdp2,Irs2,Kat2b,Uchl1,Junb,Actb,Aida,Arid5b,Max,Gclc,C3,Parp3,Slpi,Nfil3,Atm,Tent4a,Ddx4,Ahrr,Ifi213,Ptgs2,Bcl2a1d,Olr1,Hspa1b,Dusp5,Cdyl,Fam129a,Mier3,Hsph1,Rapgef2,Fam72a,Timeless,Cd38,Pik3cd,Dusp2,Marf1,Adora2b,Riox2,Htr2b,Ptch1,Helz2,Sqstm1,Ahr,Myadm,Ifi209,Trim30a,Ncoa7,Tnip1,Cav1,Lyn,Klf7,Sirt1,Mmp9,Etv3,Klf3,Ier3,Plcl2,Hhex,Irf8,Hp,Lgals9,Cenpj,Arid4a,Socs3,Plekhn1,Rnf34,Phactr4,Mecp2,Slfn1,Eif2ak2,Pnpt1,Socs1,Hopx,Aebp2,Ppp1r14b,Gtpbp2,Dcp2,Pf4,Slamf8,Sco1,Ddit4,Parp14,Mllt6,Ezr,Birc3,Birc2,Dusp16,Klf2,Spen,Hcar2,Il15,Nupr1,Dnajb2,Zc3h7a,Spry2,Ptpn2,Dcp1a,Cebpd,Myc,Tle3,Nr1h3,Etv6,Zeb1,Kdm5b,Ptk2,Arg2,Pdgfb,Lif,Serpina3f,Src,Stat3,Nr3c1,Map2k1,Hcls1,Eif4g2,Errfi1,Spint2,Prdx5,Bcor,Timp1,Crkl,Sphk1,Hat1,Cdyl2,Adar,Trib1,Tnfaip3,Rnf139,Swap70,Ifi211,Optn,Mndal,Rgs14,Gfpt1,Dusp6,Kdr,Ubash3b,Mdfic,Magohb,Rffl,Met,Myd88,Acvrl1,Mafk,Zfp281,Nck1,Arid5a,Nampt,Rbbp8,Cdkn1a,Phf6,Ifi207,Eno1,Dnajb4,Kmt5a,Egr1,Pmepa1,Notch2,Zhx2,Samsn1,Ppp1r15a,Ednrb,Dusp4,Ifi214,Bnip3,Bcl6,Gadd45b,Spred3,Cgas,Txn1,Cst7,Dusp1,Hif1a,Acvr1b,Kdm4a,Il6,Dusp8,Cflar,Sap30,Ciita,Plek,Prnp,Nmral1,N4bp1,Cd34,Lhx2,Cpeb4,Thbs1,Bmp2,Zbtb5,Rel,Casp3,Gja1,Itgav,Hk2,Plat,Ifi205,Cdk5r1,Prkce,Psmd10,Keap1,Nr4a3,Tnfsf14,Ccnd1,Nfkb1,Relb,Pcx,Zmynd15,Ppp2r5a,Acp5,Rfx5,Mdm2,Btg2,Isg15,Hmga2,Il1b,Mapkapk2,Polr2g,Trib3 |
| 1.337e-20 | -45.76 | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | MSigDB lists | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | 302 | 77 | 15632 | 1249 |
Serpine1,Fzd5,Cd86,Map4k4,Csrp1,Rgl1,Txn1,Tbc1d13,Spint2,Inhba,Nr4a3,Phyh,Slamf8,Dusp5,St3gal1,Zhx2,Slc29a3,Tpst1,Plekha5,N4bp1,Ccng2,Cers6,Ccnd1,Ly75,Fchsd2,Rab9,Rab11fip1,Casp3,St3gal6,Traf1,Kmo,Il1a,Marcksl1,Crim1,Traf5,Cd83,Cep350,Il10,Ltbp2,Birc3,Egln3,Jag1,Alas1,Akt3,Gpd2,Tnip3,Lpar1,Mmp9,Filip1l,Il13ra1,Ebi3,Cdkn1a,Ldlr,Adam19,Fscn1,Gfpt1,Cflar,Dock4,Trip10,Sqstm1,Slc7a11,Map3k6,Gadd45b,Nqo1,Optn,Sdc2,Ccl2,Nat2,Gclm,Irf4,Ccl22,Bcor,Me1,Cd80,Slamf7,Prdx1,Sdc4 |
| 1.433e-20 | -45.69 | negative regulation of apoptotic process | biological process | GO:0043066 | 925 | 142 | 20694 | 1406 |
Sphk1,Timp1,Prdx5,Jak2,Tnfaip3,Hmox1,Adar,Pim1,Optn,Plac8,Il18,Zc3h12a,Trip10,Prokr1,Notch1,Arg2,Traf2,Stk40,Nr3c1,Map4k4,Hck,Stat3,Bcl2a1a,Src,Egr3,Asns,Clec5a,Map2k1,Hcls1,Dnaja1,Birc2,Serpinb2,Edn1,Nod2,Serpine1,Spry2,Fas,Nupr1,Gclm,Myc,Pdgfrb,Sgk3,Ptk2,Mecp2,Socs3,Rnf34,Stat5a,Eif2ak2,Adora2a,Pdpn,Pf4,Slc9a1,Hdac1,Il10,Birc3,Cx3cr1,Tnfsf4,Map2k4,Nr4a1,Acvr1,Plaur,Ikbkg,Itgav,Htr2b,Casp3,Nfkb1,Chst11,Cav1,Nr4a3,Clcf1,Prkce,Psmd10,Tnfsf14,Arf4,Arel1,Btg2,Mdm2,Sirt1,Mmp9,Ier3,Axl,Grina,Pim3,Il1b,Nes,Il6,Itga5,Hif1a,Dusp1,Higd1a,Ccnd2,Bcl2a1d,Cflar,Ptgs2,Mt1,Thbs1,Tax1bp1,Cd38,Cpeb4,Plk2,Hsph1,Hspa1b,Prnp,Casp2,Igf1r,Mtdh,Phip,Irs2,Cdkn2d,Icam1,Hk1,Ccl5,Serpinb9,Insl6,Bnip3,Bcl6,Nqo1,Ednrb,Cd74,Gclc,Il1rn,Cited2,Bcl2a1b,Stxbp1,Kdr,Kitl,Rffl,Jun,Sod2,Daxx,Cx3cl1,Plk3,Tnf,Bfar,Angpt1,Ciapin1,Cdkn1a,Pim2,Asah2,Fcgr2b,Eya4,Ccl12 |
| 1.497e-20 | -45.65 | GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_DN | MSigDB lists | GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_DN | 173 | 56 | 15632 | 1249 |
Icam1,Usp18,Tab2,Psmb10,Isg15,Pml,Myo10,Tnfaip3,Tsku,Oas3,Ifit2,Casp1,C1ra,Fchsd2,Ak4,Nr4a3,Larp1,Herc6,Ripk2,Oas1g,Igf2bp2,Sp110,Il1rn,Nfkb2,Irf7,Fubp1,Txn1,Slc31a2,Nampt,Snx10,Gch1,Stoml1,Stx11,Il4ra,Ddx60,Atp2b4,Rbms2,Pfkfb3,Sgcb,Plac8,Gadd45g,Rcn1,Irf1,Dram1,Cflar,Jak2,Tnfaip2,Tnip1,Irf8,Cenpj,Abtb2,Birc3,Nfkb1,Oas1a,Tdrd7,Trim21 |
| 1.503e-20 | -45.64 | GO_REGULATION_OF_CELL_ACTIVATION | MSigDB lists | GO_REGULATION_OF_CELL_ACTIVATION | 435 | 96 | 15632 | 1249 |
Ubash3b,Irs2,Nr1h3,Nck1,Fas,Ahr,Il15,Il27,Cd80,Ptpn2,Spn,Syk,Ap3b1,Pde5a,Ifnb1,Stap1,Mmp14,Lyn,Egr3,Cdkn1a,Jak2,Cav1,Lmo4,Atm,Rictor,Zeb1,Cd74,Prdm1,Cd38,Tnfaip3,Ccdc88b,Traf2,H2-Q6,Bcl6,Adora2b,Il18,Map3k8,Nr4a3,Hmox1,Ripk2,Il1b,Vcam1,Cd274,H2-Eb1,Plek,Ccl5,Il12rb1,Inhba,Bst1,Icosl,H2-Aa,Prnp,Il4ra,Nlrp3,Abr,Tnfrsf14,H2-Q4,Ccl12,Nod2,Irf4,Peli1,Il6,Irf1,Adrb2,Tnfsf4,Ebi3,Clcf1,Tnfsf14,Il10,Rabgef1,Rasgrp1,Plscr1,Fgr,Hlx,H2-Q7,Malt1,Ripk3,Cd83,Cd40,Hsph1,Src,Axl,Casp3,Pnp2,Ptafr,Il12b,Cd55,H2-Ab1,Zc3h12a,Thbs1,Cd86,Samsn1,Pik3r6,Slc7a2,Nfkbid,Pdgfb |
| 1.575e-20 | -45.60 | GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 364 | 86 | 15632 | 1249 |
Nfkbid,Nmi,Ifi208,Samsn1,Cd86,Ifit1bl2,Pf4,Trafd1,Plcl2,Thbs1,Tapbpl,Il12b,Serpinb9,Ptger4,Cd55,Ptprj,Zc3h12a,Casp3,Ifi205,Ifi213,Axl,Notch1,H2-Q7,Hlx,Nfkbil1,Smpdl3b,Ifi203,Htra1,Il10,Rabgef1,Irf1,Tnfsf4,Irf4,Myc,Peli1,Nfkbia,H2-Q4,Ezr,Ifit1bl1,Nlrc5,Ccl12,Tnfrsf14,Tap1,Angpt1,Adar,Prnp,Il4ra,Abr,Inhba,Cd274,H2-Eb1,Kitl,Tlr3,Hmox1,Gpr68,Dhx58,H2-Q6,Bcl6,Ifi209,Tnf,Tnfaip3,Irak3,Cd14,Cd74,Prdm1,Tmem176a,Ifi211,Mndal,Atm,Trib1,Ifi204,Lyn,Tlr9,Ifnb1,Pde5a,Stap1,Ptpn2,Eif2ak2,Spn,Ifi207,Ubash3b,Mul1,Nr1h3,Ifi214,Tmem176b,Fas |
| 1.751e-20 | -45.49 | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN | MSigDB lists | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN | 277 | 73 | 15632 | 1249 |
Aoah,Eif2ak2,Cx3cr1,Plac8,Ccl12,Sod2,Tspan3,Ets2,Peli1,Vcan,Rin2,Cpd,Gadd45g,Pgs1,Egr1,Nlrp3,Slc30a1,Dmxl2,Nr1h3,Clec4e,Pid1,Itgal,Sik3,Zfp36,Plscr1,Ccrl2,Pla2g7,Rap1gap2,C3,Stat1,Ms4a6d,Rab20,Notch2,Trem1,Rnaset2b,Plod3,Casp1,Itpr1,Acpp,Tbc1d1,Pnp2,Rhoq,Cebpd,Gsr,Rsad2,Itga4,Sell,Sphk1,Myd88,Cd14,Irak3,Nampt,Ccr1,Snx10,Dusp6,Tuba4a,Rnaset2a,Ddit4,Tlr1,H2-Aa,Cxcl2,Hk2,Cd55,Slc31a1,Clec5a,Slc43a3,Cxcl10,Il18,Fpr1,Plcl2,Cmklr1,Il1b,Sp110 |
| 1.768e-20 | -45.48 | regulation of nucleic acid-templated transcription | biological process | GO:1903506 | 2865 | 318 | 20694 | 1406 |
Klf7,Cav1,Ncoa7,Tnip1,Osm,Ifi209,Pbx1,Ahr,Sqstm1,Helz2,Lmo4,Acod1,Ptch1,Riox2,Trim13,Irf8,Hhex,Arf4,Etv3,Klf3,Sirt1,Bcl9,Fos,Ier2,Traf1,Ahrr,Ifi213,Atm,Nfil3,Klf6,Casz1,Nfxl1,Rap2c,Tax1bp1,Cd38,Timeless,Hsph1,Mier3,Dusp5,Cdyl,Plscr1,Jmjd6,Kat2b,Jdp2,Nod1,Ifnb1,Trim14,Icam1,Mtdh,Mycl,Igf1r,Psip1,Cd40,Rbl1,Phip,Tshz1,Dr1,Cd74,Pou3f1,Gclc,Rnf31,Max,Arid5b,Malt1,Junb,Tcf4,Pcgf5,Jun,Sod2,Fzd1,Plk3,Tnf,Ccl3,Il1a,Daxx,Ifi204,Stat4,Cited2,Syk,Bambi,Atf3,Pml,Brwd3,Pim2,Sertad3,Taf4b,Parp10,Mxd1,Prdm1,Ikzf1,Pim1,Tlr2,Hmox1,Nfkbib,Foxp4,Klf8,Pid1,Gfi1,Notch1,Irak2,Zc3h12a,Il18,Parp9,Ripk2,Hlx,Ifi208,Znfx1,Rnf14,Gbp4,Traf2,Htra1,Ccne1,Ifi203,Jarid2,Nmi,Tnfsf8,Il18rap,Nfkbie,Trim26,Nfkbil1,Hivep2,Csf3,Nod2,Hmga1,Nfkbid,Nsd3,Lrp8,Trim21,Edn1,Resf1,Sav1,Hivep3,Med13,Dtx3l,Irak3,Irf4,Zfp36,Aim2,Adora2a,Plpp3,Atp2b4,Cmklr1,Hspa1a,Ets2,Cx3cr1,Dach1,Il10,Nr4a1,Irf2,Hinfp,Acvr1,Tnfsf4,Hdac1,Irf1,Zmynd15,Crlf3,Relb,Nfkb1,Ccnd1,Nr4a3,Keap1,Cdk5r1,Psmd10,Ifi205,Tlr3,Ikbkg,Ifnar1,Trib3,Pttg1,Tet2,Fubp1,Tal2,Il1b,Hmga2,Btg2,Rfx5,Mdm2,Ciita,Sap30,Cflar,Mamld1,Tnfrsf8,Jag1,Il6,Kdm4a,Nfkb2,Perm1,Hif1a,Acvr1b,Rel,Zbtb5,Bmp2,Lhx2,Prdm9,Nmral1,Prnp,Zhx2,Notch2,Egr1,Rgcc,Kmt5a,Dnajb4,Eno1,Brd2,Agrn,Kdm6b,Txn1,Bcl6,Ifi214,Gdf15,Ednrb,Ppp1r15a,Cacna1d,Cx3cl1,Mdfic,Nlrc5,Kdr,Egr2,Ifi207,Phf6,Rbbp8,Zfp513,Nampt,Arid5a,Etv5,Fcgr2b,Nck1,Zfp281,Acvrl1,Mafk,Myd88,Met,Inhba,Tnfaip3,Trib1,Irf7,Maff,Ddx58,Cd200,Ripk3,Traf5,Hmgn3,Cdyl2,Hat1,Sphk1,Tcea1,Bcor,Stat1,Prdx5,Jak2,Tlr6,Nlrc4,Rgs14,Mndal,Nlrp3,Plac8,Sp140,Ifi211,Pou2f2,Psma6,Batf2,Wdr43,Lif,Pdgfb,Mafg,Ptafr,Stat2,Tfec,Hcls1,Map2k1,Nr3c1,Egr3,Peli1,Hck,Stat3,Src,Nupr1,Aff1,Spen,Ifrd1,Klf2,Csrnp1,Rhoq,Birc2,Zeb1,Fosb,Etv6,Kdm5b,Nr1h3,Tle3,Myc,Cebpd,Plagl2,Dcp1a,Fzd5,Ptpn2,Aebp2,Stat5a,Ell2,Hopx,Eif2ak2,Slfn1,Plagl1,Mecp2,Rbpms,Arid4a,Cenpj,Maml2,Ezr,Mllt6,Slc9a1,Med21,Tlr9,Pf4,Nfkbia,Adrb2,Spic,Batf |
| 1.770e-20 | -45.48 | MODULE_1 | MSigDB lists | MODULE_1 | 337 | 82 | 15632 | 1249 |
Gng11,Cd34,Ifi207,Egr1,Atf3,Gbe1,Ifi214,Sdc1,Ccnd2,Dusp2,Il6,Pdpn,Myc,Gadd45g,Optn,Ccl12,Nr4a1,Ifit1bl1,Tiparp,Jun,Cited2,Zyx,Tspan3,Fos,Adam19,Ldlr,Cdkn1a,Nfil3,Filip1l,Cd200,Egr3,Ier3,Cacnb3,Ifi204,Ppp4r2,Slpi,Plscr1,Ifi211,Cnn3,Ifi203,P4ha1,Ltbp2,Gem,Mndal,Lmo4,Sema3c,Cav1,Cd14,Tnfaip3,Crim1,Nupr1,Tnc,Stat3,Rbpms,Ccnd1,Sele,Ifi213,Ifi205,Bcl6,Ifi209,Cd302,Birc2,Itpr1,Mtus1,Plat,Gng12,Cd55,Pim1,Tgfbi,Pdlim7,Ifi208,Maff,Dusp6,Csrp1,Gja1,Junb,Nampt,Ifit1bl2,Pdgfrb,Serpine1,Fosb,Ppp1r15a |
| 1.795e-20 | -45.47 | GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN | MSigDB lists | GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN | 185 | 58 | 15632 | 1249 |
Fndc3a,Adora2b,Ttc39b,Slfn3,Nfkb2,Ppp2r2a,Ccr1,Hsd17b12,Slc4a7,Dusp6,Gch1,Lcp2,Slfn4,Rrs1,Phlda1,Il12rb1,Ier2,Prdm1,Zfp281,Traf5,Notch1,Relb,Myo10,Tnf,Stat5a,Acpp,Arhgef3,Rhoq,Egr2,Tnfsf8,Mtdh,Ell2,Ier3,Jak2,Ccl4,Nfkb1,Zc3h12c,Irf8,Il10,Srxn1,Csf1,Kctd12,Atf3,Egr1,Ccnd2,Pim3,Chmp4b,Tle3,Nr4a1,Gadd45b,Nfkbia,Itgav,Fos,Peli1,Ccl2,Il6,Dusp2,Cxcl14 |
| 1.816e-20 | -45.46 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN | 168 | 55 | 15632 | 1249 |
Il15,Clec4e,Gng11,Slamf7,Samhd1,Tap1,Bcl2a1b,Sod2,Ccl12,Stat1,C3,Irf1,Ifit3b,Cflar,Ifit3,Trim21,Aim2,Il1a,Psmb10,Isg15,Sell,Myd88,Rgs3,Cd38,Gbp2,Mvp,Stat5a,Ehd1,Casp1,Sp140,Psmb9,Itpr1,Cd40,Dhx58,Bcl2a1d,Pim1,Cxcl10,Bcl2a1a,Serpinb2,Tnfsf10,Thbs1,Il15ra,Sp110,Snx10,Dusp6,Gch1,Asns,Irf7,Ube2l6,Inhba,Wars,Hk2,Uba7,Parp12,Cxcl2 |
| 1.857e-20 | -45.43 | adaptive immune response | biological process | GO:0002250 | 298 | 70 | 20694 | 1406 |
Serpina3g,Ifna2,Syk,H2-Aa,Mcoln2,Fcgr2b,H60b,Batf,Myd88,Prdm1,Fcgr1,Ifna6,Icam1,Fas,Tap2,Dennd1b,Serpinb9,Nod2,Ifnb1,Il12b,C3,Cd55,Cd74,C1ra,Rnf19b,Irf4,Gadd45g,Bcl6,Jag1,Ifna4,Il18bp,Ripk2,Ifna5,Arg2,H2-Eb1,Raet1e,Klrk1,Nfkb2,Il6,Il18rap,Stx11,Ctsc,Cd86,Sema4a,Stat3,Icosl,H2-Ab1,Spn,Pik3cd,Treml4,Clec4d,C1rl,Il4ra,Relb,Tarm1,Tnfrsf14,Lyn,Irf7,Jak2,Dbnl,Cd274,Tap1,Serpinb9b,Fgl2,Il18,Swap70,Ifna1,Slamf7,Pou2f2,Clec4n |
| 2.241e-20 | -45.24 | GSE17721_CTRL_VS_LPS_12H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_12H_BMDC_DN | 180 | 57 | 15632 | 1249 |
Rbm43,Tap1,Me1,Olr1,Slc28a2,Plac8,Rnf114,Sqstm1,Cited2,Slfn8,Mmp14,Kremen1,Dtnb,Cpd,Mtmr14,Cd200,Cd82,Esd,Birc3,Tor3a,Tnfrsf1b,Atxn7l1,Pou2f2,Socs1,Cd14,1600014C10Rik,Prpf38a,Gbp2,Plekhf2,Phldb1,N4bp1,Timp1,Psmb9,Hdac1,Gsr,Grina,Chic2,Arid5b,Mitd1,Slfn9,Il15ra,Pkp4,Sp110,Jarid2,Nampt,Snx10,Ccl5,Cacybp,Samsn1,Cnp,Plk2,Med21,Serpine1,Reps1,G3bp2,Tbc1d13,Oas2 |
| 2.261e-20 | -45.24 | regulation of protein serine/threonine kinase activity | biological process | GO:0071900 | 465 | 91 | 20694 | 1406 |
Dusp5,Thbs1,Rapgef2,Dusp2,Bmp2,Acsl1,Dusp1,Ccnd2,Higd1a,Dusp8,Ksr1,Sirt1,Pdgfc,Mlkl,Hhex,Il1b,Pik3r6,Lgals9,Trib3,Htr2b,Casp3,Psmd10,Cdk5r1,Ccnd1,Lyn,Cav1,Met,Pik3r5,Rasgrp1,Ccnj,Cdkn1a,Dusp6,Syk,Mdfic,Mapkbp1,Tnf,Kitl,Actb,Gdf15,Aida,Dusp4,Spred3,Gadd45b,Il1rn,Cd74,Igf1r,Cd40,Map3k6,Rgcc,Kat2b,Cdkn2d,Uchl1,Src,Map2k1,Ptprj,Ccne1,Traf2,Flt1,Spred1,Pdgfb,Irgm2,Ripk2,Mul1,Lpar1,Rgs14,Tlr6,Jak2,Crkl,Pim1,Tnfaip3,Trib1,Adrb2,Tlr9,Map2k4,Atp2b4,Eif2ak2,Map3k8,Pdgfrb,Fzd5,Gadd45g,Htr2a,Pde5a,Irak3,Dusp16,Edn1,Prkar2b,Dnaja1,Nod2,Mtcp1,Spry2,Ccng2 |
| 2.300e-20 | -45.22 | GO_RESPONSE_TO_INTERFERON_GAMMA | MSigDB lists | GO_RESPONSE_TO_INTERFERON_GAMMA | 131 | 48 | 15632 | 1249 |
Nos2,Irf8,Oas1a,Trim21,Mefv,Irf1,Stat1,Oasl1,Ccl4,Jak2,Ccl12,Ass1,H2-Q4,Mid1,Ccl2,Irf4,Edn1,Cx3cl1,Ccl22,Fcgr1,Ciita,Irf7,Cd86,Gch1,Ccl5,H2-Eb1,Oas2,Il12rb1,H2-Aa,Trim26,Il12b,Ptafr,Oas1g,H2-Ab1,Tlr3,Vcam1,Oas3,H2-Q6,Gbp9,Gbp4,Trim12c,Icam1,Pml,Irf2,H2-Q7,Ccl3,Gbp2,Hck |
| 2.411e-20 | -45.17 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_DN | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_DN | 186 | 58 | 15632 | 1249 |
Mxd1,Sphk1,Slco3a1,Sertad3,Il1a,Hif1a,Batf,Phf11b,Src,Dync1h1,Tnf,Dennd1b,Ifi44,Casp3,Cebpd,Ogfrl1,Ripk2,Hmox1,Ptger4,Tgfbi,Acsl5,Plaur,Gch1,Irf7,Ppp1r15a,Slc2a6,Cxcl2,G3bp2,Nlrp3,Adar,Phf11a,Tap1,Zc3hav1,Dnase1l3,Phf11c,Spsb1,Gadd45b,Ptpn2,Dock4,Nod2,Itpkc,Ell2,Stat1,Acsl1,Itga9,Phf11d,Zcchc2,Clcf1,Cflar,Jak2,H3f3b,Casp4,Pstpip2,Trim21,Cd69,Tdrd7,Il18rap,Rnf19a |
| 2.411e-20 | -45.17 | GSE7852_TREG_VS_TCONV_THYMUS_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_THYMUS_UP | 186 | 58 | 15632 | 1249 |
Crim1,Cd38,Mdfic,Cd83,Gbp3,Rnf135,Prdm1,Fgl2,Bcl2a1d,Cish,Tnfsf8,Pnp2,Itgb8,Slc15a3,Ttc39c,Dusp1,Casp1,Bcl2a1a,Osbpl3,Pim1,Ttc39b,Ptger4,Dusp5,Oas1g,Ppp2r3a,Gch1,Myadm,Ccl5,Ahr,Plagl1,Prnp,Dtwd1,Arrdc4,Tmem176b,Tpi1,Chst11,Phlpp1,Dusp4,Gadd45g,Fcgr2b,Tspan3,Gadd45b,Bcl2a1b,Igf1r,Fam162a,Pmepa1,Nfil3,Notch2,Sh3bgrl2,Rgs1,Odc1,Ebi3,Kif5c,Oas1a,Plscr1,Gem,Casp4,Tnfrsf1b |
| 2.411e-20 | -45.17 | PLASARI_TGFB1_TARGETS_10HR_UP | MSigDB lists | PLASARI_TGFB1_TARGETS_10HR_UP | 186 | 58 | 15632 | 1249 |
Junb,Dusp6,Gch1,Ppp1r15a,Serpine1,Pdgfb,Inhba,Maff,Hk2,Rnf19b,Dusp5,Ptgs2,Cmklr1,Gcnt2,Plaur,Htr2b,Slc2a1,Cd40,Serp1,Gpr84,Tnc,Egr2,Cdyl2,Hspa2,Plk3,Ier2,Csrnp1,Lif,Spata13,Sphk1,Pdgfc,Hck,Tnfaip3,Flnb,Hivep3,Jag1,Rap1gap2,Endod1,Itga5,Mmp9,Ier3,Lrrc8c,Nfil3,Pmepa1,Flt1,Gadd45b,Ass1,Abcb1a,Il6,Chst11,Dusp4,Cxcl14,Lrp8,Gmppb,Cx3cl1,Papss2,Dusp14,Olr1 |
| 2.545e-20 | -45.12 | GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_UP | 192 | 59 | 15632 | 1249 |
Gch1,Nampt,Snx10,Klf2,Noc4l,Sap30,Mmp13,Oas1g,Dnaja2,Rnf19b,Nr4a3,Cxcl10,Ptgs2,Kitl,Clic4,Bcl2a1a,Txnrd1,Tank,Bcl6,Ankrd17,Casp3,Minpp1,Bcl2a1d,Mdm2,Fabp3,Gbp3,Traf1,Zfp281,Usp18,Rnf34,Cd83,Cd164,Ppp1r15b,Ikbkg,Pdk3,Gbp7,Plscr1,Csf1,Oas1a,Stat1,Dck,Max,Mtdh,Ifi35,Azi2,Odc1,Rbms1,Jak2,Bcl2a1b,Sqstm1,Ptpn2,Pla2g4a,Irgm2,Tor1aip2,Rars,Atf3,Fas,Il15,Tap1 |
| 2.853e-20 | -45.00 | positive regulation of developmental process | biological process | GO:0051094 | 1539 | 201 | 20694 | 1406 |
Tspo,Ehd1,Cmklr1,Kif3c,Abcb1a,Ptger4,Acvr1,Tnfsf4,Cx3cr1,Rab21,Il10,Irf1,Hdac1,Lrp8,Serpine1,Carmil1,Nfkbid,Flrt2,Edn1,D16Ertd472e,Sav1,Itgb8,Ccr3,Mmp14,Phldb1,Zfp36,Irak3,Hlx,Ripk2,Mul1,Scn1b,Cxcl9,Hap1,Ccne1,Gcnt2,Csf3,Pim1,Tlr2,Hmox1,Scarf1,Notch1,Trip10,Gfi1,Zc3h12a,Il18,Tnf,Il1a,Ifi204,Ccl3,Sod2,Jun,Tcf4,Fzd1,Bambi,Cited2,Syk,Rasgrp1,Ccr1,Pml,Ikzf1,Noct,Prdm1,Ccl5,Kat2b,Msr1,Nlgn2,Mtdh,Cd40,Igf1r,Cd74,C3,Malt1,Junb,Ptgs2,Mmd,Fos,Cyfip1,Adgrl2,Rapgef2,Myadm,Clcf1,Lyn,Il4ra,Itpr1,Ptch1,Dbnl,Pik3r6,Cd83,Cd274,Il15ra,Lgals9,Axl,Sirt1,Mmp9,Fam20c,Ap3b1,Socs1,Hopx,Pdpn,Cxcl1,Stat5a,Glipr2,Socs3,Mecp2,Eef1e1,Vegfc,Ezr,Pf4,Adrb2,Csf1,Il15,Triobp,Spen,S1pr2,Rac3,Kdm5b,Zeb1,Ptk2,Cebpd,Pdgfrb,Myc,Pde5a,Ccl8,Htr2a,Gpc1,Lpar1,Flt1,Arg2,Pdgfb,Lif,Eif4g2,Hcls1,Map2k1,Egr3,Src,Stat3,Gpr68,Sema3c,Nr3c1,Cysltr2,Trib1,Tnfaip3,Inhba,Flrt3,Jak2,Stat1,Sphk1,Crkl,Nlrp3,Akt3,Rgs14,Tnfrsf1b,Cx3cl1,P2ry2,P2ry12,Kitl,Kdr,H2-Aa,Etv5,Casp8,Acvrl1,Met,Serp1,Nck1,Egr1,Rgcc,Notch2,Cgas,Agrn,Il12b,Cst7,Mark2,Pdlim7,Bnip3,Bcl6,Gdf15,Jag1,Cflar,Il2rg,Acvr1b,Hif1a,Itga5,Il6,Kdm4a,Bmp2,Ddhd1,Sema4a,Tnfsf9,Plk2,Thbs1,Cd34,Tnfsf14,Ccnd1,Gja1,Hk2,Nfkbiz,Tlr3,Il1b,Hmga2,Isg15,Fubp1 |
| 3.341e-20 | -44.85 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | 132 | 48 | 15632 | 1249 |
Edn1,Spry2,Bnip3,Dusp4,Nfkbia,Fos,Sdc4,Pfkfb3,Pim3,Dusp14,Nfkbiz,Rars,Atf3,Palld,Tpi1,Egr1,Gbe1,Zfp36,Jag1,Eno2,P4ha1,Ptch1,Dusp16,Fam162a,Frmd6,Il13ra1,Dnajb4,Sat1,Tnc,Errfi1,Prdx5,Klf6,Homer1,Slc2a1,Clcn5,Mxd1,Csrnp1,Rnd1,Jmjd6,Phlda1,Hk2,Plk2,Higd1a,Pgk1,Smox,Ptger4,Rcan1,Chic2 |
| 3.707e-20 | -44.74 | MODULE_171 | MSigDB lists | MODULE_171 | 117 | 45 | 15632 | 1249 |
Peli1,Ifi44,Cebpd,Sdc2,H2-Q4,Nlrc5,Ifit1bl1,Klf6,Oas3,H2-Q6,Pnpt1,Cd14,Il15,Samhd1,Gbp2,Hvcn1,H2-Q7,Isg15,Sell,Stat2,Pttg1,H2-Aa,Plscr1,Isg20,Kctd12,Syne2,Csf3,Oas1a,Rnf31,Ifit1bl2,Cd86,Samsn1,Thbs1,Tnfsf10,Adam19,Cmklr1,Vcam1,Sp110,Trem1,Oas1g,Cd200,Ifi35,H2-Ab1,Fpr1,Kcna3 |
| 3.727e-20 | -44.74 | programmed cell death | biological process | GO:0012501 | 857 | 134 | 20694 | 1406 |
Jak2,Prdx5,Nlrc4,Uaca,Crkl,Pim1,Usp53,Hmox1,Ripk3,Traf5,Tnfaip3,Cycs,Inhba,Tnfrsf1b,Zc3h12a,Il18,Dnase1l3,Notch1,Xaf1,Traf2,Ero1l,Nek6,1600014C10Rik,Ikbke,Mul1,Ripk2,Tnfsf15,Ggct,Bcl2a1a,Dyrk2,Phlda1,Bcl2l11,Casp4,Lcn2,Casp1,Csrnp1,Birc2,Sp110,Nupr1,Hcar2,Fas,Fzd5,Irak3,Myc,Gclm,Gadd45g,Etv6,Sav1,Casp7,Rnf34,Ppp2r1b,Serpina3g,Aim2,Egln3,Irf1,Phlpp1,Apaf1,Ddit4,Nr4a1,Xkr8,Map2k4,S100a8,Birc3,Casp3,Itgav,Itpr1,Gja1,Ikbkg,Sqstm1,Tlr3,Hk2,Tnfsf14,Psmd10,Cav1,Nfkb1,Kremen1,4930453N24Rik,Ier3,Sirt1,Mlkl,Arel1,Il1b,Acp2,Pim3,Trib3,Pmaip1,Dram1,Acvr1b,Atm,Il6,Rmdn3,Traf1,Bcl2a1d,Cflar,Ifit2,Tmem219,Plscr1,Tax1bp1,Spn,Ctsc,Casp2,Serpinb9,Srgn,Cdkn2d,Nod1,Slc4a7,Malt1,Gsdmd,Ppp1r15a,Bnip3,Traf3ip2,Gclc,Gadd45b,Bcl2a1b,Tpx2,Tnf,Plk3,Daxx,Il1a,Ifi204,Sod2,Jun,Rffl,Fam162a,Kitl,Tnfsf10,Myd88,Ift57,Pim2,Asah2,Cdkn1a,Casp8,Ciapin1,Pml |
| 3.955e-20 | -44.68 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_UP | 143 | 50 | 15632 | 1249 |
Bst1,Plk2,Ppp1r15a,Samsn1,Cd274,Sesn3,Plaur,Rcl1,Dcbld2,Clic4,Nfkb2,Tnfsf10,Il12b,Nr4a3,Ptger4,Egr2,Relb,Myo10,Tnfaip3,Etv5,Isg15,Kmo,Icam1,Ddx58,Malt1,Egln3,Hivep3,Zfp36,Nfkb1,Birc3,Dnajb2,Cd300lf,Fam102b,Adrb2,Trib1,Filip1l,Etnk1,Stap1,Parp14,Prokr1,Irf4,Gadd45b,Nfkbia,Nr4a1,Angpt1,Zbp1,Herc3,Ppm1l,Cdk5r1,Nfkbiz |
| 3.969e-20 | -44.67 | regulation of MAPK cascade | biological process | GO:0043408 | 744 | 122 | 20694 | 1406 |
Dusp6,Kdr,Ccl4,Syk,Ccl3,Il1a,Mdfic,Mapkbp1,Tnf,Cx3cl1,Jun,Kitl,Met,Angpt1,Myd88,Prdx1,Pik3r5,Fcgr2b,Ccl12,Rasgrp1,Ccr1,Atf3,Nox1,Cd40,Igf1r,Map3k6,Vrk2,Icam1,Ccl5,Nod1,Notch2,Uchl1,Dusp4,Gdf15,Aida,Spred3,Gadd45b,Il1rn,Cd74,C3,Dusp1,Il6,Mid1,Dusp8,Cflar,Ksr1,Dusp5,Rapgef2,Hsph1,Thbs1,Dusp2,Bmp2,Htr2b,Tlr3,Psmd10,Prkce,Clcf1,Osm,Tnip1,Cav1,Lyn,Pdgfc,Ccl22,Mlkl,Il1b,Pik3r6,Trib3,Eif2ak2,Ccl7,Glipr2,Map3k8,Ccl2,Adrb2,Tlr9,Phlpp1,Map2k4,Ezr,Sema4c,Dusp16,Edn1,Dnaja1,Fas,Nod2,Spry2,Ptpn2,Fzd5,Pdgfrb,Gadd45g,Htr2a,Irak3,Pde5a,Ccl8,Ccl9,Flt1,Traf2,Pdgfb,Spred1,Lif,Stk40,Ripk2,Lpar1,Mul1,Src,Gcnt2,Map4k4,Map2k1,Ptprj,Fpr2,Errfi1,Marco,Jak2,Tlr6,Crkl,Sphk1,Tlr2,Cysltr2,Trib1,Inhba,Zc3h12a,Notch1,Scimp,Rgs14 |
| 4.126e-20 | -44.63 | GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_UP | 165 | 54 | 15632 | 1249 |
Mmp14,Samd9l,Dusp4,Agrn,Gramd1a,Trip10,Tspan3,Slamf7,Pim3,Etv3,Pdss1,Isg20,Rasgrp1,Xaf1,P4ha1,Ppp1r15b,Ifit3,Rgs1,Cflar,Cdkn1a,Stat1,Ifit3b,Trib1,Ifi44,Itgb8,Stat3,Tapbp,N4bp1,Batf,Hck,Psme1,Parp10,Traf1,Dtx3l,Icam1,Usp18,Slc2a6,Nmi,Tmeff1,Inhba,Rapgef2,Gch1,Snx10,Osm,Igsf8,Irf7,Irak2,Epsti1,Il15ra,Plaur,Ptger4,Clec4d,Slc43a3,Ak4 |
| 4.401e-20 | -44.57 | activation of innate immune response | biological process | GO:0002218 | 96 | 38 | 20694 | 1406 |
Nlrc4,Tlr6,Tlr3,Ifih1,Ifi205,Prkce,Tnip3,Tlr2,Ddx58,Clec4e,Ifi209,Nod2,Tnip1,Cd14,Ifi214,Irak2,Cd300lf,Irak3,Ifi211,Tlr1,Mndal,Cgas,Mapkapk2,Lgals9,Klrk1,Ifi204,Aim2,Tnf,Irgm2,Tifa,Ifi208,Ripk2,Myd88,Tlr9,Nfkbia,Cd86,Trim12c,Ifi203 |
| 4.503e-20 | -44.55 | GSE17721_LPS_VS_CPG_1H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_CPG_1H_BMDC_DN | 194 | 59 | 15632 | 1249 |
Pim2,Cd200,Kpna3,Cpeb4,Rcsd1,Rgs1,Clcf1,Cdkn1a,Plekhn1,Irf8,Ppp4r2,Ampd3,Pstpip2,Rnf19a,Sirt1,Nfkbiz,Cdk5r1,Pfkfb3,Nfkbia,Dusp2,Edn1,Dtnb,Ankrd24,Map3k8,Serpinb9,Chic2,Bambi,Serpinb2,Clic4,Inpp1,Il1rn,Il1b,Il15ra,Brd2,Plek,Cdyl,Samsn1,Ddit4,Cxcl2,Traf1,Mapkbp1,Apaf1,Stau1,Phldb1,Abcc5,Slc25a37,Tnf,Hspa1a,Birc2,Arhgef3,Swap70,Ttc39c,Rffl,Rab21,Ccng2,Mecp2,Aebp2,Tlk2,Mdm2 |
| 4.648e-20 | -44.52 | positive regulation of cell adhesion | biological process | GO:0045785 | 412 | 84 | 20694 | 1406 |
Sdc4,Tnfsf4,Rasgrp1,Nck1,Ikzf1,Irf1,Angpt1,Ccl2,Adam19,Stat5a,P2ry12,Plekha2,Socs1,Tnf,Ap3b1,Pdpn,Cx3cl1,Ptger4,Vegfc,H2-Aa,Cited2,Syk,Plpp3,Kdr,Cd74,Ptk2,Ccdc88b,Rac3,Il12b,Itga4,Bcl6,Myo10,Malt1,Nfkbid,Carmil1,Il15,Icam1,Ccl5,Csf1,Vcam1,Triobp,Cd86,Ptprj,Spn,Map4k4,Hsph1,Thbs1,Icosl,Src,Gcnt2,Tnfsf9,H2-Ab1,Egr3,Il2rg,Hlx,Ripk2,Cyth3,Piezo1,Cd80,Il6,Atm,Ptafr,Itga5,Lgals9,Nlrp3,Cd274,Cd83,Pik3r6,Il1b,Hsd17b12,Il18,Itgal,Il12rb1,Il4ra,Cav1,Tnfrsf14,Prkce,Nr4a3,Myadm,Tnfsf14,Nfkbiz,Crkl,Jak2,Itgav |
| 4.653e-20 | -44.51 | regulation of cell differentiation | biological process | GO:0045595 | 1908 | 234 | 20694 | 1406 |
Cd74,Junb,Malt1,Ccl5,Ifnb1,Kat2b,Jdp2,Msr1,Igf1r,Nlgn2,Mycl,Ankrd17,Rasgrp1,Ccr1,Ikzf1,Noct,Prdm1,Pilrb1,Il27,Ifi204,Daxx,Il1a,Ccl3,Tnf,Zswim4,Fzd1,Jun,Sod2,Tcf4,Bambi,Syk,Cd83,Pik3r6,Axl,Il15ra,Lgals9,Mmp9,Sirt1,Fam20c,Clcf1,Pbx1,Ahr,Myadm,Kremen1,Il4ra,Cav1,Lyn,Klf7,Itpr1,Ptch1,Lmo4,Dbnl,Rapgef2,Cd38,Ptgs2,Fos,Mmd,Casz1,Cyfip1,Sav1,Mmp14,Phldb1,Zfp36,Ctla2a,Fas,Lrp8,Flrt2,Nfkbid,Tmem176b,Carmil1,Serpine1,Sema4c,Edn1,Stap1,D16Ertd472e,Tnfsf4,Acvr1,Rab21,Cx3cr1,Irf1,Ust,Hdac1,Ehd1,Tspo,Kif3c,Lnpk,Cmklr1,Mov10,Ptger4,Abcb1a,Notch1,Scarf1,Gfi1,Trip10,Fgl2,Il18,Zc3h12a,Tomm70a,Tlr2,Foxp4,Ldlr,Hap1,Ccne1,Csf3,Gcnt2,Map4k4,Ripk2,Mul1,Hlx,Lrp4,Cxcl9,Tmem178,Scn1b,Cnot4,Agrn,Il12b,Mark2,Pdlim7,Ednrb,Gdf15,Bcl6,Sinhcaf,Rgcc,Zhx2,Notch2,Cxcl14,Mosmo,Etv5,Katna1,Casp8,Met,Acvrl1,Tmem176a,Nck1,P2ry2,Cx3cl1,P2ry12,Kitl,Kdr,Ubash3b,H2-Aa,Isg15,Hmga2,Il1b,Fubp1,Trib3,Mdm2,Cdk5r1,Keap1,Tnfsf14,Ccnd1,Itgav,Nfkbiz,Bmp2,Sema4a,Tnfsf9,Cd34,Plk2,Lhx2,Jag1,Lox,Cflar,Il2rg,Acvr1b,Hif1a,Kdm4a,Il6,Prkx,Ccl9,Rac3,Zeb1,Clec2d,Prag1,Ptk2,Dync1i2,Ptpn2,Cebpd,Htr2a,Myc,Pde5a,Ccl8,Il15,Csf1,Ociad1,Spry2,Sipa1l1,Triobp,Csf3r,Ifrd1,S1pr2,Spen,Sdc2,Tlr9,Pf4,Nfkbia,Slamf8,Eif2ak2,Ap3b1,Socs1,Hopx,Pdpn,Stat5a,Glipr2,Socs3,Vegfc,Mecp2,Nlrp3,Rgs14,Tnfrsf1b,Vasn,Maff,Trib1,Inhba,Errfi1,Jak2,Stat1,Crkl,Sphk1,Rap1gap2,Map2k1,Hcls1,Eif4g2,Stat3,Egr3,Nr3c1,Gpr68,Sema3c,Gpc1,Lpar1,Flt1,Mafg,Cxcl10,Pdgfb,Lif |
| 5.093e-20 | -44.42 | regulation of tumor necrosis factor superfamily cytokine production | biological process | GO:1903555 | 165 | 50 | 20694 | 1406 |
Il12b,Tlr1,Irak3,Fzd5,Zfp36,Cd14,Nod1,Nod2,Ifih1,Cx3cr1,Il10,Rasgrp1,Arid5a,Hdac1,Tlr9,Pf4,Myd88,Angpt1,Ccl2,Tspo,Cx3cl1,Ccl3,Ptger4,Ccl4,Lgals9,Mapkapk2,Axl,Cd274,Zc3h12a,Sirt1,Acp5,Il18,Tnfaip3,Gpr18,Trim30a,Ddx58,Tlr2,Tlr3,Tlr6,Jak2,Errfi1,Ptprj,Thbs1,Spn,Nfkbil1,Cd34,Ripk2,Tnfrsf8,Ptafr,Arg2 |
| 5.206e-20 | -44.40 | regulation of leukocyte mediated immunity | biological process | GO:0002703 | 245 | 62 | 20694 | 1406 |
Nectin2,Clec2d,Il12b,Cd55,C3,Parp3,Fzd5,Malt1,Bcl6,Tap2,H2-Q7,Serpinb9,Rabgef1,Ifnb1,Nod2,Cd40,Fgr,Fcgr2b,Tnfsf4,Arid5a,Rasgrp1,H60b,H2-Q6,Tlr9,Fcgr1,Tnf,Cxcl1,Rsad2,Stat5a,Stxbp1,Syk,Nlrp3,Tap1,Pik3r6,Il1b,Lgals9,Il18,Tnfrsf1b,H2-T24,Dnase1l3,Tlr2,H2-Q4,Hmox1,Ripk3,Clcf1,Ddx58,H2-T22,Il4ra,Lyn,H2-T10,Tlr3,Il18rap,Adora2b,Pvr,H2-M2,Spn,Abr,Ptafr,Traf2,Klrk1,Raet1e,Il6 |
| 5.466e-20 | -44.35 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_UP | 183 | 57 | 15632 | 1249 |
Zhx2,Il15ra,Nfkb2,Bcl2a1a,Nr4a3,Ak4,Dusp5,Stx11,Rapgef2,Nrp2,Plk2,Gch1,Txn1,Tnfaip3,Relb,Gys1,Cd83,Traf5,Traf1,Il1a,Rsad2,Bcl2a1d,Psma6,Ly75,Sat1,Eno1,Dusp1,Vrk2,Gfi1,Rgs1,Tnfaip2,Cflar,Ifit3b,Cd200,Socs3,Ifi35,Stat4,Psme2,Isg20,Rel,Ifit3,Ltbp2,Nfkb1,Eno2,Abtb2,Tap1,Dnase1l3,Klf7,Il15,Sgcb,Tpi1,Dusp4,Bnip3,Bcl2a1b,Sod2,Gadd45b,Nfkbia |
| 5.466e-20 | -44.35 | GSE17721_LPS_VS_PAM3CSK4_8H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_8H_BMDC_UP | 183 | 57 | 15632 | 1249 |
Asah2,Ccr1,Snx10,Csrp1,Tyk2,Pde7b,Stxbp3,Nsmaf,Map3k8,Rnf19b,Crkl,St3gal1,Smc5,Gtpbp2,Plat,Tnfsf10,P2ry12,Rgs14,Swap70,Dusp1,Klf6,Plod3,Casp1,Glipr2,Mafk,Tnc,1110038F14Rik,Sat1,Minpp1,Tnfsf8,Batf2,Dbnl,Pde1b,Rffl,Gbp3,Sertad3,Mxd1,Cd164,Ptch1,Psmb8,Ccne1,Stat4,Etv6,Csf1,Zfp36,Rcsd1,Ap3m2,Asf1a,Rap2c,Rnf114,Tra2a,Dusp2,Atf3,Enpp4,Hinfp,Tspo,Pnpt1 |
| 5.653e-20 | -44.32 | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN | 166 | 54 | 15632 | 1249 |
Csrnp1,Socs1,Cd38,P4ha2,Ifit2,Homer1,Timp1,Tank,Stat3,Irgq,Dennd1b,Mdm2,Gpr68,Rsad2,Bcl2a1d,Ptger4,Bcl2a1a,Irak2,Lacc1,Plaur,Cmpk2,Nampt,Slc31a2,Samsn1,Ddit4,Btg2,Slc7a5,Phlda1,AA467197,Maff,Nfkbiz,Atf3,Mapkapk2,Egr1,Pde3b,Tle3,Slc7a11,Bcl2a1b,Jun,Peli1,Rin2,Nod2,Dusp4,Dram1,Ebi3,Itpkc,Oasl1,Clcf1,Dnajb2,Clic5,Dcun1d3,Ccrl2,Rnf19a,Etv6 |
| 5.763e-20 | -44.30 | GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_UP | 189 | 58 | 15632 | 1249 |
Parp14,Nat2,Katna1,Kremen1,Gadd45b,Crbn,Itgav,B4galt4,Rras2,Rnd3,Hinfp,Zbp1,Atp11b,Samhd1,Slc28a2,Stxbp1,Arl4a,Nxf1,Ifit3,Adap2,Plekha2,Fscn1,Dr1,Notch2,Ccl4,Asf1a,Rgs1,Tmem219,Vrk2,Tmod3,Aida,Ifit3b,Tbc1d1,Gbp9,Gbp4,Rab9,Cd83,Myd88,Cd164,Mthfr,Rhoh,Tab2,Icam1,Rnf135,Caml,Noc4l,Snx2,Uba7,Plk2,Pdgfrb,Plcl2,Dek,Gtpbp2,Kitl,Dcbld2,Fndc3a,Pim1,Nsmaf |
| 5.865e-20 | -44.28 | ELVIDGE_HYPOXIA_UP | MSigDB lists | ELVIDGE_HYPOXIA_UP | 155 | 52 | 15632 | 1249 |
Gja1,Gdf15,Daam1,Serpine1,Ddit4,Pdgfb,Tmeff1,Phlda1,Maff,Hk2,Pim1,Adora2b,Ak4,Tgfbi,Lox,Vegfc,Plaur,Glrx,Pgk1,Dusp1,P4ha2,Klf6,Itpr1,Slc2a1,Nr3c1,Sat1,Ccng2,Gys1,Eno2,P4ha1,Cav1,Isg20,Flnb,Egln3,Met,Fam162a,Nfil3,Gadd45b,Plac8,Fos,Tiparp,Jun,Cited2,Bnip3,Bbx,Tra2a,Atf3,Egr1,Bcor,Gbe1,Pfkfb3,Klf7 |
| 5.911e-20 | -44.27 | REACTOME_INNATE_IMMUNE_SYSTEM | MSigDB lists | REACTOME_INNATE_IMMUNE_SYSTEM | 219 | 63 | 15632 | 1249 |
Zbp1,Ifna1,Tlr6,Mapkapk2,Nlrp3,Peli1,Ifnb1,Ifna5,Dusp4,Nod2,Nfkbia,Nlrc5,Jun,Nlrc4,Fos,Tax1bp1,Ppp2r1b,C3,Tlr9,Tlr2,Mefv,Map2k4,Irf1,Nfkbib,Casp2,Ikbkg,Birc3,Casp8,Casp4,Cd14,Myd88,Nod1,Tnfaip3,Ifna2,Irak3,Ripk3,Irf2,Aim2,Isg15,Ifih1,Rnf135,Cd180,Ddx58,Tab2,Dhx58,Casp1,Tank,Birc2,Traf2,Irak2,Nfkb2,Ikbke,Ripk2,Cd55,Tlr3,Ifna6,Tlr1,Ube2l6,Uba7,Dusp6,Txn1,Irf7,Map2k1 |
| 6.015e-20 | -44.26 | negative regulation of multicellular organismal process | biological process | GO:0051241 | 1336 | 181 | 20694 | 1406 |
Fas,Tmem176b,Serpine1,Nfkbid,Nod2,Stap1,Sema4c,Sav1,Lnpep,Zfp36,Irak3,Svbp,Rab11fip1,Tspo,Cmklr1,Ptger4,Atp2b4,Tnfsf4,Cx3cr1,Il10,Plau,Irf1,Gpr18,Tlr2,Hmox1,Foxp4,Notch1,Gfi1,Zc3h12a,Fgl2,Tomm70a,Gbp4,Mul1,Hlx,Lrp4,Spred1,Tmem178,Ldlr,Nmi,Jarid2,Map4k4,Nfkbil1,Rabgef1,Ifnb1,Parp3,Cd74,Pde4b,Aida,Tnf,Mapkbp1,Il1a,Tcf4,Pde3b,Cited2,Ccr1,Pml,Col4a2,Noct,Angpt1,Pilrb1,Pbx1,Ahr,Trim30a,Cav1,Lyn,Klf7,Kremen1,Il4ra,Ptch1,Acod1,Dhx58,Hhex,Cd274,Cd83,Il15ra,Lgals9,Axl,Sirt1,Mmp9,Plcl2,Ptgs2,Abr,Casz1,Cd86,Adora2b,Dusp5,Rapgef2,Cd38,Il15,Dock4,Spry2,Ifrd1,Klf2,S1pr2,Prag1,Clec2d,Tle3,Nr1h3,Dync1i2,Ptk2,Ptpn2,Myc,Pde5a,Socs1,Stat5a,Mecp2,Tulp3,Ezr,D1Ertd622e,Ccl2,Slamf8,Evl,Tlr9,Adrb2,Pf4,Nfkbia,Cd200,Vasn,Tnfaip3,Trib1,Pgk1,Inhba,Tlr6,Jak2,Timp1,Stat1,Bcor,Errfi1,Rap1gap2,Nlrp3,Tnfrsf1b,Plac8,Lpar1,Cxcl10,Arg2,Pdgfb,Lif,Stat3,Sema3c,Gpr68,Srgn,Rgcc,Zhx2,Calcrl,Il12b,Mefv,Ednrb,Bcl6,Gdf15,Cx3cl1,P2ry2,Ubash3b,Katna1,Fcgr2b,Acvrl1,Gpr35,Met,Tmem176a,Cdk5r1,Nfkb1,Relb,Gja1,Il1b,Hmga2,Procr,Acp5,Mdm2,Jag1,Hif1a,Il6,Kdm4a,Bmp2,Ctsc,Rel,Sema4a,Prnp,Plk2,Lhx2,Thbs1,Cacnb3,Cd34 |
| 6.366e-20 | -44.20 | identical protein binding | molecular function | GO:0042802 | 1878 | 234 | 20217 | 1400 |
Gbp3,Psme2,Daxx,Ifi214,Tnip1,Casp8,Mmp9,Ass1,Tap1,Bcl6,Prdx1,Nod1,Gbp2,Stat4,Sat1,Gadd45g,Acvr1,Ifi207,Ubash3b,Pdgfb,Bnip3,Ldlr,Slamf8,Rbbp8,Hvcn1,Irak2,Nqo1,Hp,Homer1,Ifi213,Jun,Ifit3,Cacybp,Trim12c,Lztfl1,Pdgfc,Fbxo4,Flt1,Nlrp3,Dcp1a,Samhd1,Htra1,Tpst1,Ddx58,Casp2,Klrk1,Nr3c1,Daam1,Rasgrp1,Adora2a,Spata13,Foxp4,Trim21,Nmi,Atf3,Nos2,Ggct,Hmgcs1,Rab9,Dst,Actb,Sdc1,Tlr3,Ezr,Lnpk,Mitd1,Adrb2,Apaf1,Traf2,Relb,Zhx2,Wars,Gch1,Ppfibp2,Zbp1,Sdc2,Pml,Hhex,Tcf4,Ptgs2,Pvr,Tnf,Ripk3,Jmjd6,Fcho2,Ifih1,Eif2ak2,Plek,Mcm6,Eno1,Hap1,Slc39a13,Eno2,Cd69,Aim2,Bcl2a1d,Slamf7,Kcnj2,Odc1,Tlr6,Keap1,Dgkh,Cd38,Tra2a,Snx2,Tap2,Prnp,Hk1,Mefv,Met,Ikbkg,Asns,Jak2,Sqstm1,Traf5,Glipr2,Ripk2,Clcn5,Rbpms,Myd88,Srm,Nr4a3,Tnfsf14,Acpp,Kdr,Birc2,Irak3,Mthfd1l,Ifi208,Sav1,Tlr2,Piezo1,Tnfsf10,Gdf15,Tlr1,Sh3bp4,Tnfaip3,Cst7,Txnrd1,Mul1,Ehd1,Fzd1,Flnb,Stxbp1,Prag1,Ifi204,Bcl2a1b,Nlrc4,Kctd12,Cenpj,Ctsc,Casp1,Traf1,Nampt,Pfkl,P4ha1,Ccl5,Ifi209,Pcx,Mlkl,Mndal,Malt1,Mcm10,Olr1,Alas1,Timeless,Ifit3b,Nectin2,Optn,Cav1,Chmp4b,Esd,Sirt1,Trip10,Nr4a1,Gsr,Slc31a1,Gpsm2,Csf1,Bmp2,Max,Nrp2,Tpm4,Trip13,Msantd3,Nectin4,Slc16a1,Ext1,Ptk2,Icosl,Mvp,Ifi203,Gca,Ccl4,Bcl2a1a,Flrt3,Inhba,Sod2,Ifi205,Stat3,Igf1r,Mid1,Itpr1,Rnf135,Hmox1,Stat1,Nfkbia,Iigp1,Stat2,Lrp4,Hdc,Ahr,Crlf3,Lcn2,Zc3hav1,Nmral1,Sdc4,Nfkb1,Marcks,Mdm2,Fas,Tpi1,Crkl,Dck,Rcan1,Riox2,Slc25a12,Il12b,Slc2a1,Rab3ip,Ifi211,Nlgn2,Gbp2b,Cebpd |
| 6.861e-20 | -44.13 | LTE2_UP.V1_DN | MSigDB lists | LTE2_UP.V1_DN | 178 | 56 | 15632 | 1249 |
Ifi44,Phf11b,Oas3,Psmb9,Myo10,Notch1,Ifih1,Isg15,Ddx58,Usp18,Nmi,Ube2l6,Oas2,Parp12,Ifit1bl2,Irf7,Gca,Ptges,Sp110,Oas1g,Herc6,Dusp2,Ifrd1,Slc7a11,Bcl2l11,Eif2ak2,Ifit1bl1,Cnn2,Tspo,Slc16a1,Phf11a,Tap1,Phf11c,Samhd1,Usp25,Atf3,Ddx60,Plscr1,Trim14,Tdrd7,Oas1a,Jag1,Psat1,Gem,Casp8,Ifit3,Cav1,Jak2,Prkar2b,Nfil3,Igf1r,Oasl1,Egr3,Ifi35,Ifit3b,Phf11d |
| 6.944e-20 | -44.11 | GO_IMMUNE_SYSTEM_DEVELOPMENT | MSigDB lists | GO_IMMUNE_SYSTEM_DEVELOPMENT | 550 | 110 | 15632 | 1249 |
Irf8,Il10,Sirt1,Jag1,Ifi203,Irf1,Sema4a,Azi2,Pik3cd,Tmod3,Gfi1,Clcf1,Fam20c,Kdr,Hcls1,Tet2,Tiparp,Jun,Bcl2l11,Sbds,Irf4,Ikzf1,Il6,Egr1,Angpt1,Ifna1,Adar,Klf2,Cd86,Arid4a,Junb,Jarid2,Snx10,Csf3,Pdgfb,Ifna6,Ifi208,Clec5a,Il12b,Clec4d,Ptger4,Herc6,Plcl2,Prkx,Swap70,Psmb9,Ifi205,Ifi213,Axl,Src,Casp3,Pde1b,Hif1a,Jmjd6,Malt1,Hhex,Itga4,Rhoh,Pml,Cd164,Ripk3,Relb,Casp8,Mndal,Lmo4,Atm,Etv6,Pou2f2,Ifi211,Csf1,Ifi204,Lyn,C3,Mmp9,Notch2,Jak2,Ptpn2,Cited2,Spn,Syk,Ifna5,Ifnb1,Ciapin1,Ifi214,Fas,Ifi207,Il15,Cd34,Clec4e,Fzd5,Map2k1,Rrs1,Plek,Inhba,Crkl,Vcam1,Nfkb2,Kitl,Bcl6,Ifi209,Tnf,Klf6,Rsad2,Tnfsf8,Batf2,Cd74,Tnfaip3,Ifna2,Batf,Pbx1 |
| 7.322e-20 | -44.06 | GSE18893_TCONV_VS_TREG_2H_CULTURE_DN | MSigDB lists | GSE18893_TCONV_VS_TREG_2H_CULTURE_DN | 184 | 57 | 15632 | 1249 |
Psme2,Csf1,Isg20,Syne2,Tmem176a,Oas1a,Dcun1d3,Psmb8,Plekha2,Il10,Cdkn1a,Agpat4,Dyrk2,Socs3,Etnk1,Tlr2,Irf1,Cacnb3,Ctsc,Irgm2,Plac8,B4galt4,Gpr18,Rbm43,Zbp1,Tap1,Tmem176b,Abr,Arrdc4,Arl4a,P2ry14,Kat2b,Stxbp3,Icosl,Ube2l6,Uba7,Parp12,G3bp2,Snx2,Brwd3,Nampt,Vps54,Trafd1,Oas1g,Fndc3a,Tapbpl,Serpinb9,Ehd1,Cd40,Ankrd17,Gbp2,Stau1,Psme1,Psmb10,Dtx3l,Ddx58,Icam1 |
| 7.322e-20 | -44.06 | GSE17721_0.5H_VS_12H_LPS_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_12H_LPS_BMDC_DN | 184 | 57 | 15632 | 1249 |
Itga4,Upp1,Arg2,Prpf38a,Mdfic,Gbp2,N4bp1,Tcf4,Gsr,Smc5,Grina,Arid5b,Slfn9,Mitd1,Il15ra,Nampt,Ccl5,Gch1,Samsn1,Serpine1,Rab10,G3bp2,Oas2,Tbc1d13,Abr,Atf3,Cx3cl1,P2ry14,Pikfyve,Rbm43,Slc28a2,Olr1,Me1,Sqstm1,Rnf114,Cited2,Irgm2,Slfn8,Ccl2,Stard5,Mmp14,Katna1,Kremen1,Cpd,Dtnb,Mtdh,Cd200,Mafg,Znrf1,Jak2,Cflar,Dusp16,Atm,Nfkb1,Cep350,Pou2f2,Eef1e1 |
| 7.668e-20 | -44.01 | GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_UP | MSigDB lists | GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_UP | 190 | 58 | 15632 | 1249 |
Rars,Fas,Gclc,F10,Plau,Pim3,Ahr,Atp11b,Flt1,Il4i1,Stap1,Il6,Edn1,Irf4,Tmem171,Taf4b,Egr3,Ifi35,Tlr2,Rab20,Map2k4,Rcn1,Cflar,Dcun1d3,Gem,Casp4,Alas1,Pstpip2,Procr,Met,Stx6,Hivep3,Slc39a14,Plk3,Magohb,Socs1,Ube2f,Gnb4,Hsph1,Stat5a,Cd40,Pnp2,Rnf24,Ubtd2,Egr2,Nfkbie,Ripk2,Kdm6b,Gpr85,Nr4a3,Serpinb2,Cxcl1,Cmklr1,Plek,Pde4b,Igsf9,Hk2,Nfkbid |
| 7.668e-20 | -44.01 | GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN | 190 | 58 | 15632 | 1249 |
Traf1,Kmo,Icam1,Sla,Batf,Plagl2,Gypc,Stat5a,Ehd1,Tnf,Timp1,Tnfsf8,Bcl2a1d,Acvr1,Dnaja2,Ptprj,Ptger4,Map3k8,Ak4,Thbs1,Serpinb2,Bcl2a1a,Cxcl1,Zhx2,Il1b,Il15ra,Ccl5,Map4k4,Ifit1bl2,Slc7a8,Rrs1,Adora2a,Cxcl2,Fas,Abr,Nlrp3,Sdc4,Dusp14,Tnfrsf14,Bcl2a1b,Sqstm1,Ifit1bl1,Gadd45b,Cited2,Trip10,Il6,Pdpn,Ikzf1,Sdc2,Rin2,Tra2a,Pim2,Tlr2,Tnip1,Atm,Gem,Irf8,Ampd3 |
| 8.090e-20 | -43.96 | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | 423 | 93 | 15632 | 1249 |
Phlda1,Ifi208,Antxr1,Map4k4,Abcc4,Fmnl2,Igf2bp2,Dcbld2,Gng12,Kif3c,Ptgs2,Tgfbi,Pim1,Tbc1d1,Nr3c1,Ifi205,Dse,Timp1,Psmb9,Clmp,Casp1,Axl,Ifi213,Mdfic,Crim1,Malt1,Met,Ifi203,Jag1,Htra1,Akt3,Layn,Zc3h12c,Ltbp2,Fam20c,Pik3cd,Aida,Socs3,Il6,Rai14,Spry2,Gng11,Plau,Prnp,Pttg1,Pde7b,Inhba,Eya4,Ext1,Vps54,Serpine1,Tap2,Flrt2,Gja1,Inpp1,Irak2,Plat,Cxcl1,Adora2b,Psmb6,B3gnt5,Dock10,Glipr2,Ifi209,Dpy19l1,Slc25a37,Tnfaip3,Pdgfc,Etv5,Upp1,Kctd12,Zeb1,Ifi211,Mndal,Cav1,Atm,Fscn1,Lyn,Lpar1,Ifi204,Rnf145,Dnajb4,Mid1,Ctsc,Itgav,Ifi207,Extl2,Col4a2,Sgcb,Il15,Ifi214,Ubash3b,Fas |
| 8.484e-20 | -43.91 | SENESE_HDAC1_TARGETS_UP | MSigDB lists | SENESE_HDAC1_TARGETS_UP | 416 | 92 | 15632 | 1249 |
Akt3,Slc39a14,Met,Ifi203,Psat1,Birc3,Tmod3,Myc,Chst11,Ezr,Nfkbia,Slc7a11,Ccl12,Dock4,Plau,Ppfibp1,Nfkbiz,Prnp,Ccnd2,Nlrp3,Phlda1,Ifi208,G3bp2,Maff,Nampt,Gch1,Bcl2a1a,Serpinb2,Igf2bp2,Vegfc,Gng12,Glrx,Abcc4,Cd55,Scyl2,Zc3h12a,Dusp5,Slc43a3,Nsmaf,Pnp2,Bcl2a1d,Mlkl,Cebpd,Gsr,Ifi213,Itpr1,Ifi205,Bmp2,Smg7,Il1a,Ifi211,Usp12,Mndal,Gem,Cpeb4,Max,Mmp9,C3,Ifi204,Trib1,Klf3,Sqstm1,Sod2,Bcl2a1b,Hmga1,Slc16a1,Slamf7,Ifi207,Spred1,Atp11b,Fas,Cyth3,Dcp2,Ifi214,Cxcl2,Tor1aip1,Irak2,Nfkb2,Kitl,Stip1,Pcgf5,Fcho2,Ogfrl1,Errfi1,Dock10,Cers6,Dpy19l1,Slc25a37,Ifi209,Tnfaip3,Upp1,Atp11a |
| 8.595e-20 | -43.90 | GO_ACTIVATION_OF_IMMUNE_RESPONSE | MSigDB lists | GO_ACTIVATION_OF_IMMUNE_RESPONSE | 366 | 85 | 15632 | 1249 |
Ikbke,Irak2,Ripk2,Psmb6,H2-Ab1,Ptprj,Cd55,Tlr3,Clec4d,Nr4a3,Tlr1,Ifi208,H2-Aa,Pde4b,H2-Eb1,Irf7,Lcp2,Cd86,Cd14,Myd88,Nod1,Hck,Myo10,Tnfaip3,Relb,Irak3,Cd38,Malt1,Psme1,Aim2,Fgr,Trim12c,Psmb10,Ifih1,Cd180,Ddx58,Tab2,Dennd1b,Psma6,C1ra,Ifi213,Src,Ifi205,Tank,Birc2,Ifi209,Psmb9,Tnip1,Actb,C3,Ptk2,Tlr9,Tlr2,Lyn,Pik3cd,Ifi204,Tnip3,Cacnb3,Psme2,Ifi211,Ifi203,Rnf31,Ikbkg,Nfkb1,Psmb8,Clec4n,Birc3,Casp8,C1rl,Mndal,Marco,Clec4e,Fcgr1,Ifi207,Mapkapk2,Tlr6,Nck1,Ifi214,Prkce,Nod2,Syk,Nfkbia,Nlrc4,Psmd10,Cyfip1 |
| 9.230e-20 | -43.83 | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_UP | 179 | 56 | 15632 | 1249 |
Dbnl,Tnfsf8,Lztfl1,Ifit2,Usp53,Gypc,Insl6,Cd40,Hspa1a,Bfar,Myo10,Psme1,Cd180,Slco3a1,Nmi,Car13,Hk2,Dgka,Tyk2,Ccl5,Asah2,Lad1,Slfn4,Serpine1,Slfn3,Inpp1,Clic4,Plat,Sp110,Sec24b,Keap1,Tlr3,Oas1g,4930453N24Rik,Tapbpl,Tor1aip2,Abcb1a,Ciita,Sdc4,Gng11,Samhd1,Pgs1,Tpx2,Gmppb,Trim21,Nfkbib,Oas1a,Hk1,Jdp2,Kdr,Nlgn2,Vrk2,Ebi3,Denr,Aida,Rab20 |
| 9.230e-20 | -43.83 | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | 179 | 56 | 15632 | 1249 |
Pgk1,Thbs1,Ak4,Atp10a,Oas1g,Fndc3a,Zc3h12a,Rapgef2,Ube2l6,Med21,Jarid2,Nampt,Cd164,Jmjd6,Trim12c,Mxd1,Plk3,Rbpms,Nfkbie,Psma6,Irgq,Micall2,Casp3,Dse,Tpst1,Ehd1,Phf11b,Vrk2,Phf11d,Dnajb4,Hmgcs1,Casp7,Ebi3,Mmp9,Pim2,Tmod3,Hivep3,Oas1a,Etv6,Procr,Ampd3,Atxn7l1,Abtb2,Vcpip1,Phf11c,Plau,Phf11a,Cdc42ep2,Fas,Irf4,Fcgr2b,Pdpn,Stap1,Dock4,Eif2ak2,Gadd45b |
| 9.674e-20 | -43.78 | ZHU_CMV_8_HR_UP | MSigDB lists | ZHU_CMV_8_HR_UP | 46 | 28 | 15632 | 1249 |
Tnfaip3,Egr1,Pml,Irf2,Isg15,Il6,Pla2g4a,Ifnb1,Ifit1bl1,Nr4a1,Dnaja1,Oas1g,Cd55,Cxcl10,Nr4a3,Ptgs2,Alas1,Trim21,Trim26,Oas2,Wars,Oas1a,Slc39a14,Ccl5,Gch1,Ifit1bl2,Psmb8,Nampt |
| 9.783e-20 | -43.77 | GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_DN | MSigDB lists | GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_DN | 185 | 57 | 15632 | 1249 |
Zcchc2,Nlgn2,Ifi35,Ell2,Stat1,Cd200,Kif5c,Slc25a22,Ifit3b,Isg20,Ep400,Xaf1,Cd69,Tor3a,Ifit3,P2ry2,Cenpj,Enpp4,Usp25,Parp14,Irgm2,Ifit1bl1,Sod2,Slfn3,Prkx,Tnfsf10,Il15ra,Pkp4,Cmpk2,Herc6,Tlr3,Usp31,Trib3,Slamf8,Cox18,Cxcl10,Ube2l6,Sap30,Uba7,Ifit1bl2,Lgals9,Slfn4,Irf7,Ifit1,Hck,Usp18,Stat2,Upp1,Ddx58,Isg15,Fut8,Gbp9,Gbp4,Dhx58,Tapbp,Rsad2,Insl6 |
| 9.783e-20 | -43.77 | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | 185 | 57 | 15632 | 1249 |
Osm,Samsn1,Rnaset2a,Jarid2,Slc2a6,Tlr1,Rilpl1,Uchl1,Dusp28,Dcbld2,Igf2bp2,Plaur,Cldnd1,Pilrb1,Cd40,Ttc39c,Spryd7,Klf6,Gpr68,Nfkbie,Fgl2,Fabp3,Sphk1,Malt1,Tnfaip3,Relb,Clcn5,Cd14,Zc3h12c,Smpdl3b,Timeless,Map2k4,Itga5,Mmp9,Lrrc8c,Cdkn1a,Frmd6,Pmepa1,Abcc1,Rnaset2b,Ccl4,Ets2,Zyx,Slc7a11,Fam43a,Chst11,Phlpp1,Mmp14,Stap1,Pdpn,Irf4,Gclm,Tmem171,Plagl1,Stxbp1,Lpcat2,Pilrb2 |
| 9.984e-20 | -43.75 | GSE2706_R848_VS_LPS_2H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_LPS_2H_STIM_DC_DN | 135 | 48 | 15632 | 1249 |
Atxn7l1,Isg20,Jag1,Lap3,Il10,Ifit3,Oasl1,Egr3,Ifit3b,Dnajb4,Cacnb3,Tnip3,Peli1,Ifnb1,Fam43a,Ifit1bl1,Cited2,D16Ertd472e,Znfx1,Col4a2,Zc3hav1,Vcpip1,Egr1,Ddx60,Ube2l6,Trim26,Inhba,Gch1,Ifit1bl2,Lcp2,Ppp1r15a,Il1b,Herc6,Clec5a,Ptgs2,Tnfsf8,Ifi44,Plekhf2,Ifit2,Otud1,Gbp2,Csrnp1,Ch25h,Prdm1,Aim2,Ifih1,Isg15,Il1a |
| 1.007e-19 | -43.74 | cellular response to oxygen-containing compound | biological process | GO:1901701 | 1044 | 152 | 20694 | 1406 |
Cd180,Kdm6b,Il1rn,Il12b,Bnip3,Pde4b,Actb,Malt1,Nqo1,Cd14,Calcrl,Nod1,Ifnb1,Kat2b,Irs2,Cxcl2,Egr1,Ccl5,Rab10,Tnip3,Icam1,Mtdh,Larp1,Igf1r,Phip,Vcam1,Ccl12,Arid5a,Gch1,Fcgr2b,Prdx1,Agtrap,Myd88,Jun,Sod2,P2ry12,Tnf,Sh3bp4,Pde3b,Trib3,Axl,Irf8,Il1b,Cd274,Mdm2,Pdgfc,Sirt1,Mmp9,Lyn,Cav1,Nfkb1,Ahr,Cxcl11,Prkce,Cdk5r1,Nr4a3,Htr2b,Itpr1,Ptch1,Acod1,Cd86,Rapgef2,Cpeb4,Mt1,Thbs1,Timeless,Prnp,Plscr1,Cflar,Fos,Cyfip1,Il6,Atm,Cd80,Ptk2,Zeb1,Nr1h3,Itga4,Ptpn2,Fcgr4,Pdgfrb,Zfp36,Serpine1,Nod2,Esd,Socs7,Stap1,Rhoq,Cx3cr1,Ezr,Il10,Nr4a1,Ddit4,Glrx,Tnfsf4,Gbp2,Slc9a1,Nfkbia,Adrb2,Pf4,Irf1,Ccl2,Cxcl1,Stat5a,Socs1,Ccl7,Ptger4,Atp2b4,Akt3,Pid1,Gramd1a,Gfi1,Nlrp3,Irak2,Tnfrsf1b,Zc3h12a,Il18,Tnfaip3,Inhba,Cxcl3,Pim1,Tlr2,Ripk3,Sphk1,Nfkbib,Crkl,Jak2,Tlr6,Prdx5,Stat1,Fpr2,Cmpk2,Lcn2,Casp1,Ldlr,Pdk3,Casp4,Nfkbil1,Nr3c1,Src,Stat3,Ripk2,Lpar1,Sesn3,Irgm2,Nos2,Pdgfb,Klrk1,Cxcl9,Cxcl10,Traf2,Ptafr |
| 1.050e-19 | -43.70 | regulation of gene expression | biological process | GO:0010468 | 3857 | 396 | 20694 | 1406 |
Brd2,Agrn,Ednrb,Tra2a,Carhsp1,Ifi214,Inpp5b,Etv5,Cdkn1a,Phf6,Ifi207,Zfp513,Nampt,Acvrl1,Nck1,Cdk5r1,Keap1,Nfkb1,Ifnar1,Ifi205,Tlr3,Il1b,Trib3,Polr2g,Tet2,Rfx5,Btg2,Cnn2,Tnfrsf8,Ptgs2os2,Lox,Phgdh,Il2rg,Perm1,Acvr1b,Nfkb2,Bmp2,Zbtb5,Nmral1,Cpeb4,Lhx2,Csf1,Nupr1,Zc3h7a,Rhoq,Spen,Ifrd1,Kdm5b,Etv6,Fosb,Tle3,Nr1h3,Ptpn2,Fzd5,Cebpd,Eif2ak2,Slfn1,Plagl1,Pnpt1,Aebp2,Stat5a,Plekhn1,Arid4a,Tnc,Birc3,Mllt6,Batf,Ccl2,Med21,Dcp2,Adrb2,Nfkbia,Gtpbp2,Ddx58,Hmgn3,Traf5,Irf7,Tnfaip3,Inhba,Rictor,Tlr6,Jak2,Sphk1,Tcea1,Nlrp3,Rgs14,Zc3hav1,Tnfrsf1b,Rnf139,Ifi211,Sp140,Plac8,Wdr43,Psma6,Lif,Eif4g2,Map2k1,Stat2,Peli1,Nr3c1,Icam1,Jmjd6,Kat2b,Igf2bp2,Dr1,Mycl,Mtdh,Rbl1,Cd40,Gclc,Pou3f1,Max,Arid5b,Plk3,Tnf,Daxx,Il1a,Pcgf5,Tcf4,Jun,Bambi,Cited2,Sertad3,Taf4b,Parp10,Atf3,Ikzf1,Mxd1,Myadm,Pbx1,Cav1,Klf7,Osm,Acod1,Sqstm1,Lgals9,Etv3,Sirt1,Ifi213,Bcl9,Traf1,Ier2,Casz1,Nfil3,Cyfip1,Ddx4,Klf6,Marf1,Nfxl1,Plscr1,Dusp5,Hsph1,Pik3cd,Tax1bp1,Mier3,Spn,Nsd3,Fas,Hmga1,Edn1,Resf1,Sav1,Med13,Mmp14,Irf4,Dtx3l,Cmklr1,Plpp3,Irf2,Ppp1r15b,Cx3cr1,Dach1,Il10,Klhl25,Irf1,Foxp4,Nfkbib,Gfi1,Zc3h12a,Il18,Ythdf1,Rnf14,Ripk2,Hlx,Znfx1,Stk40,Traf2,Ldlr,Smg7,Il18rap,Ifi203,Ccne1,Jarid2,Hivep2,Tut7,Trim26,Nfkbil1,Egr1,Rgcc,Notch2,Zhx2,Dnajb4,Eno1,Kmt5a,Fut8,Kdm6b,Txn1,Cst7,Ppp1r15a,Bcl6,Gdf15,Cx3cl1,Mdfic,Cacna1d,Magohb,Egr2,Kdr,Gfpt1,Nlrc5,Arid5a,Fcgr2b,Mafk,Met,Serp1,Myd88,Zfp281,Ccnd1,Psmd10,Nr4a3,Pcx,Crlf3,Zmynd15,Relb,Gja1,Ikbkg,Tal2,Hmga2,Pttg1,Mapkapk2,Fubp1,Mdm2,Mamld1,Jag1,Ciita,Sap30,Cflar,Hif1a,Il6,Kdm4a,Rel,Prnp,Fbxo4,Thbs1,Prdm9,Cd34,Aff1,Spry2,Csrnp1,Birc2,Klf2,Zeb1,Plagl2,Dcp1a,Myc,Hopx,Ell2,Mecp2,Maml2,Ezr,Parp14,Spic,Slc9a1,Pf4,Tlr9,Cd200,Adar,Maff,Ripk3,Trib1,Prdx5,Bcor,Stat1,Nlrc4,Hat1,Crkl,Mndal,Apba1,Optn,Pou2f2,Batf2,Mafg,Ptafr,Pdgfb,Hcls1,Tapbp,Lcn2,Tfec,Egr3,Src,Hck,Stat3,Serpinb9,Trim14,Ccl5,Ifnb1,Nod1,Jdp2,Tshz1,Msr1,Phip,Wars,Psip1,Igf1r,Larp1,Cd74,Malt1,Junb,Rnf31,Ifi204,Ccl3,Sod2,Fzd1,Stat4,Syk,Ago3,Pim2,Ccr1,Brwd3,Pml,Noct,Prdm1,Ahr,Ifi209,Ncoa7,Tnip1,Ptch1,Lmo4,Helz2,Hhex,Trim13,Irf8,Klf3,Arf4,Ahrr,Olr1,Fos,Tent4a,Atm,Cdyl,Fam129a,Timeless,Cd38,Lrp8,Serpine1,Nfkbid,Nod2,Stap1,Tsku,Trim21,Xrn1,Tent2,Itgb8,Hivep3,Ctla2a,Zfp36,Irak3,Aim2,Adora2a,Ets2,Mov10,Ptger4,Atp2b4,Hinfp,Acvr1,Nr4a1,Tnfsf4,Adam19,Hdac1,Pim1,Hmox1,Tlr2,Klf8,Tdrd7,Notch1,Pid1,Tiparp,Irak2,Nos2,Gbp4,Ifi208,Parp9,Htra1,Nfkbie,Tnfsf8,Gcnt2,Csf3 |
| 1.052e-19 | -43.70 | negative regulation of cellular metabolic process | biological process | GO:0031324 | 2506 | 285 | 20694 | 1406 |
Myc,Cebpd,Ptpn2,Ptk2,Nr1h3,Tle3,Etv6,Zeb1,Kdm5b,Klf2,Spen,Dusp16,Birc2,Dnajb2,Spry2,Nupr1,Dcp2,Ppp1r14b,Mllt6,Parp14,Ezr,Birc3,Ddit4,Sco1,Phactr4,Mecp2,Arid4a,Cenpj,Socs3,Rnf34,Plekhn1,Aebp2,Eif2ak2,Slfn1,Hopx,Socs1,Optn,Ifi211,Rnf139,Swap70,Rgs14,Mndal,Crkl,Cdyl2,Hat1,Sphk1,Errfi1,Spint2,Bcor,Timp1,Prdx5,Trib1,Tnfaip3,Adar,Nr3c1,Stat3,Src,Hcls1,Eif4g2,Lif,Pdgfb,Serpina3f,Ifi214,Dusp4,Bcl6,Bnip3,Ednrb,Samsn1,Ppp1r15a,Cst7,Spred3,Gadd45b,Txn1,Cgas,Kmt5a,Eno1,Dnajb4,Notch2,Zhx2,Pmepa1,Egr1,Nck1,Zfp281,Myd88,Met,Mafk,Acvrl1,Rbbp8,Nampt,Ifi207,Phf6,Cdkn1a,Arid5a,Ubash3b,Gfpt1,Dusp6,Rffl,Mdfic,Btg2,Mdm2,Rfx5,Acp5,Mapkapk2,Trib3,Hmga2,Isg15,Il1b,Hk2,Ifi205,Plat,Itgav,Gja1,Casp3,Relb,Nfkb1,Ppp2r5a,Zmynd15,Nr4a3,Prkce,Cdk5r1,Psmd10,Ccnd1,Tnfsf14,Cd34,N4bp1,Thbs1,Cpeb4,Plek,Nmral1,Prnp,Zbtb5,Rel,Bmp2,Kdm4a,Il6,Hif1a,Dusp1,Cflar,Sap30,Ciita,Dusp8,Gadd45g,Svbp,Irak3,Dtx3l,Zfp36,Ctla2a,Prkar2b,Dnaja1,Tent2,Xrn1,Trim21,Serpinb2,Edn1,Stap1,Radx,Serpine1,Nsd3,Phlpp1,Hdac1,Irf1,Il10,Dach1,Tnfsf4,Ppp1r15b,Nr4a1,Hinfp,Plaur,Atp2b4,Ptger4,Mov10,Plpp3,Hspa1a,Ets2,Tspo,Adora2a,Serpina3g,Il18,Zc3h12a,Gfi1,Pid1,Notch1,Serpinb9b,Rhoh,Chmp4b,Foxp4,Klf8,Hmox1,Jarid2,Ccne1,Ifi203,Hap1,Nfkbie,Ptprj,Tlk2,Nmi,Spred1,Usp25,Znfx1,Parp9,Ifi208,Serpinb6b,Mvp,Gbp4,Arid5b,Aida,Max,Junb,Actb,C3,Parp3,Gclc,Larp1,Igf1r,Rbl1,Mtdh,Dr1,Wars,Irs2,Jdp2,Kat2b,Cdkn2d,Uchl1,Rabgef1,Serpinb9,Prdm1,Mxd1,Angpt1,Noct,Ikzf1,Pml,Atf3,Parp10,Ago3,Caml,Cited2,Ric1,Fzd1,Jun,Tcf4,Ifi204,Daxx,Tnf,Plk3,Mmp9,Sirt1,Ier3,Etv3,Klf3,Irf8,Hp,Hhex,Sqstm1,Riox2,Htr2b,Ptch1,Ncoa7,Tnip1,Klf7,Cav1,Lyn,Trim30a,Myadm,Ahr,Ifi209,Mier3,Cd38,Timeless,Fam72a,Rapgef2,Hsph1,Cdyl,Dusp5,Fam129a,Hspa1b,Dusp2,Marf1,Slpi,Atm,Tent4a,Nfil3,Bcl2a1d,Ifi213,Ahrr,Ptgs2 |
| 1.094e-19 | -43.66 | negative regulation of response to external stimulus | biological process | GO:0032102 | 369 | 78 | 20694 | 1406 |
Socs3,Nlrc5,Ubash3b,Ptger4,Cx3cl1,Mapkbp1,Adora2a,Plau,Slamf8,Adrb2,Prdm1,Trafd1,Ccl12,Fcgr2b,Siglece,Cx3cr1,Cdkn1a,D1Ertd622e,Il10,Ccr1,Parp14,Stap1,Sema4c,Rabgef1,Serpinb9,Tap2,Serpine1,Calcrl,Nod2,Ptpn2,Ctla2a,Zfp36,Irak3,Fabp7,Il12b,Clec2d,Nr1h3,Mefv,Cst7,Arg2,Dusp1,Htra1,Pdgfb,Mul1,Abr,Smpdl3b,Sema3c,Thbs1,Nfkbil1,Cd34,Spn,Cacnb3,Samhd1,Nmi,Ldlr,Aoah,Fpr2,Sema4a,Gja1,Acod1,Uaca,Adar,Cd200,Gpr18,Tnfaip3,Trib1,Kremen1,Nfkb1,Zc3h12a,Ier3,Tnfrsf1b,Acp5,Fgl2,Dhx58,Tap1,Notch1,Nlrp3,Lgals9 |
| 1.239e-19 | -43.54 | GSE8515_IL1_VS_IL6_4H_STIM_MAC_UP | MSigDB lists | GSE8515_IL1_VS_IL6_4H_STIM_MAC_UP | 180 | 56 | 15632 | 1249 |
Slamf7,Cd80,Sdc4,Il6,Scarf1,Nfkbia,Trip10,Ccl4,Tnip1,Rap2c,Pim2,Egr3,Ebi3,Acsl1,Ier3,Alas1,Ampd3,Rasgrp1,Ccrl2,Stat4,Jag1,Nfkb1,Tor3a,Sik3,Rel,Cd83,Tnfaip3,Relb,Marcksl1,Plk3,Traf1,Icam1,Mdm2,Tnf,Ehd1,Rhbdf2,Serpinb2,Nfkb2,Cxcl1,Snn,Il1b,Zhx2,Ripk2,Kdm6b,Ptger4,Serpinb9,Ptgs2,Slc43a3,Slc2a6,Btg2,Cxcl2,Maff,Stx11,Junb,Plek,Pde4b |
| 1.239e-19 | -43.54 | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_UP | 180 | 56 | 15632 | 1249 |
Ptger4,Il12b,Cdc42ep4,Pim1,Osgin2,Gtpbp2,Uba7,Snx2,G3bp2,Ifih1,Myd88,Batf,Prpf38a,Insl6,Plod3,Cd40,Ankrd17,D1Ertd622e,Sele,Kpna3,Endod1,Max,Etnk1,Ifit3b,Lpar1,Rgs1,Kdr,Notch2,Fscn1,Birc3,Ogfr,Plekha2,Adap2,Casp4,Ifit3,Mov10,Csf1,Trim21,Hat1,Rars,Ddx60,Atf3,Gmppb,Arl4a,Phip,Pttg1,Pnpt1,Rras2,Slc28a2,Atp11b,Ccl12,Tagln,Nat2,Il6,Peli1,Ifnb1 |
| 1.355e-19 | -43.45 | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | 815 | 142 | 15632 | 1249 |
Mxd1,H2-Q7,Pml,Stat2,Hck,N4bp1,Itpr1,Tank,Cd40,Gpr84,Nr3c1,Carhsp1,Dennd1b,Bcl2a1d,Smox,Ptger4,Kdm6b,Cd55,Dusp5,Scyl2,Bcl2a1a,Il1rn,Slfn9,Clic4,Lacc1,Fmnl2,Tfec,Abcc4,Trafd1,Nampt,Arid4a,Myo1b,Ube2l6,Noc4l,Phlda1,Wars,Maff,Atf3,Egr1,Prnp,Arrdc4,Phf11c,Tap1,Rab32,H2-Q4,Slc7a11,Ccl12,Tra2a,Taf4b,Samd9l,Nqo1,Triobp,Filip1l,Rcn1,Phf11d,Sema4a,Azi2,Acsl1,Tagap,Armc8,Mier3,Psat1,Lnpep,Ifit3,Ksr1,Plscr1,Ube2e2,Slc39a14,Jag1,Cd69,F11r,Etv5,Rab3ip,Plagl2,Slc25a37,Phf11b,Abcc5,Plekha5,Homer1,H2-Q6,Bcl6,Tcf4,1110038F14Rik,Phgdh,Rab11fip1,Errfi1,Ogfrl1,B3gnt5,Ccng2,St3gal1,Trib3,Il18,Gtpbp2,Sec24a,Inpp1,Pkp4,Rcl1,Plek,Slc12a9,Dusp6,Flrt2,Ppp1r15a,Asns,Ddit4,Sap30,Wdfy1,Bst1,Rapgef2,Fas,Fpr2,Kat2b,Arl4a,Nr1h3,Kif9,Sgcb,Phf11a,Me1,Syk,Itgav,Psip1,Bcl2a1b,Ass1,B4galt4,Slfn8,Ifrd1,Ift57,Cpeb4,Sema4c,Trib1,Ifit3b,Mthfd2,Gfpt1,Gbp2b,Cdkn1a,Nfil3,Wdr43,S100a8,Sco1,Casp8,Lmo4,Zscan29,Il18rap |
| 1.364e-19 | -43.44 | activation of immune response | biological process | GO:0002253 | 271 | 65 | 20694 | 1406 |
Ifi214,Rnf31,Pde4b,Irak3,Cd14,Fpr1,Malt1,C3,Cd55,C1ra,Tlr1,Cgas,Ifih1,Nod2,Nfkbid,Rgcc,Tnip3,Dennd1b,Tlr9,Nfkbia,Myd88,Fcgr2b,Syk,Cmklr1,Ifi204,Aim2,Tnf,Irak2,Cd300lf,Ifi211,Zc3h12a,Mapkapk2,Lgals9,Mndal,Crkl,Tlr3,Nfkbiz,Ifi205,Nlrc4,Tlr6,Lcp2,Tnip1,Themis2,Lyn,Nr4a3,Prkce,Tlr2,Ddx58,C1rl,Clec4e,Ifi209,Spn,Cacnb3,Cd38,Icosl,Ifi203,Fpr2,Trim12c,Cd86,Klrk1,Irgm2,Bcl2a1d,Tifa,Ripk2,Ifi208 |
| 1.555e-19 | -43.31 | GSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_DN | MSigDB lists | GSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_DN | 175 | 55 | 15632 | 1249 |
Clec4e,Cd80,Zbp1,Dusp14,Stxbp1,Plagl1,Bbx,Kcnj2,Phlpp1,Ass1,Nlrc5,Cdkn1a,Sema4c,Cpeb4,Max,Trib1,Flnb,Fabp7,Hat1,Cd69,Jag1,Rnf19a,P4ha1,Casp4,Gbp7,Cd83,Relb,Myo10,Rhoc,Tnfaip3,Cd38,Mxd1,Marcksl1,Isg15,Sphk1,Slc39a13,Hif1a,Icam1,Pde1b,Apobec3,Armcx6,P2ry13,Prkx,Osbpl3,Snn,Vegfc,Dcbld2,Dusp5,Rnf19b,Cxcl10,Il12b,Gpr132,Stx11,Txn1,Cd274 |
| 1.658e-19 | -43.24 | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_DN | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_DN | 181 | 56 | 15632 | 1249 |
Cers6,Pnp2,Phgdh,Ankrd17,Timp1,Ctu1,Casp1,Plekha5,Parp8,Prpf38a,Stau1,Hvcn1,Rnf135,Mxd1,Fzd1,Inhba,Csf3,Reps1,Osm,Tap2,Brd2,Ifit1bl2,Gca,Nfxl1,Osbpl3,St7,Dnaja2,Scyl2,Ap3b1,Cept1,Aftph,Msr1,Psip1,Klf3,Ifit1bl1,Slc28a2,Pnpt1,Pilra,Slc30a1,Il4ra,Dcp2,Usp25,Ddx60,Itgal,Ppp1r15b,Stard7,Dusp16,Mob3c,Hcls1,Clcn7,Azi2,Odc1,Rnf145,C3,Stat1,Casp7 |
| 1.753e-19 | -43.19 | GO_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_KINASE_ACTIVITY | 717 | 130 | 15632 | 1249 |
Pdgfc,Rgs3,Mvp,Tnfaip3,Irak3,Tab2,Cd74,Errfi1,Hspa2,Traf2,Tnf,Htr2b,Il1b,Pilrb1,Irak2,Kitl,Adora2b,Trib3,Map3k8,Tlr3,Crkl,Ripk2,Rapgef2,Flrt2,Lcp2,Fzd5,Map2k1,Pdgfrb,Dusp6,Ccl5,Spred1,Dusp14,Rbl1,Sdc4,Pilrb2,Ubash3b,Kat2b,Cdk5r1,Tpx2,Mul1,Irs2,Nck1,Cdkn2d,S1pr2,Pde5a,Dusp4,Gadd45g,Stap1,Dusp2,Ptpn2,Dnaja1,Eif2ak2,Gadd45b,Syk,Dusp16,Cdkn1a,Jak2,Rap2c,Trib1,Lpar1,Lyn,Ptk2,Tlr9,Mmd,Csf1,Cav1,Lmo4,Ikbkg,Daxx,Ripk3,Mdfic,Nod1,Bmp2,Fgr,Socs1,Malt1,Hhex,Ccnd1,Casp3,Dusp8,Dbnl,Cish,Rgs14,Cd40,Dusp1,Src,Hsph1,Thbs1,Pim1,Il12b,Cxcl10,Fpr1,Ptprj,Dusp5,Uchl1,Pdgfb,Tnfsf15,Pik3r6,Txn1,Mark2,Atp2b4,Angpt1,Htr2a,Adar,Ccnd2,Tlr6,Lrp8,Mapkapk2,Nod2,Spry2,Edn1,Il6,Ppp2r5a,Psmd10,Flt1,Map3k6,Cenpe,Nlrc5,Flrt3,Pik3r5,Igf1r,Socs7,Prkar2b,Aida,Adrb2,Acsl1,Socs3,Sirt1,Rasgrp1,Ccne1 |
| 1.757e-19 | -43.19 | regulation of tumor necrosis factor production | biological process | GO:0032680 | 163 | 49 | 20694 | 1406 |
Mapkapk2,Axl,Lgals9,Sirt1,Acp5,Il18,Zc3h12a,Tnfaip3,Tlr2,Gpr18,Ddx58,Trim30a,Tlr3,Errfi1,Tlr6,Jak2,Ptprj,Spn,Nfkbil1,Cd34,Thbs1,Ripk2,Tnfrsf8,Ptafr,Arg2,Tlr1,Il12b,Irak3,Cd14,Zfp36,Fzd5,Nod1,Nod2,Ifih1,Il10,Cx3cr1,Arid5a,Rasgrp1,Tlr9,Pf4,Hdac1,Myd88,Angpt1,Ccl2,Tspo,Ccl3,Cx3cl1,Ptger4,Ccl4 |
| 1.828e-19 | -43.15 | SENESE_HDAC3_TARGETS_UP | MSigDB lists | SENESE_HDAC3_TARGETS_UP | 450 | 96 | 15632 | 1249 |
Slc16a1,Slfn5,Atp11b,Ifi207,Spred1,Fas,Ifi214,Ubash3b,Dcp2,Mmp14,Sod2,Sqstm1,Klf3,Ets2,Hmga1,Adam19,Dusp16,Oasl1,Mmp9,Cpeb4,Ifit3b,Ifi204,Trib1,Ifi211,Mndal,Gem,Ube2f,Sav1,Tnfaip3,Pdgfc,Prdm1,Itgb8,Sat1,Errfi1,Usp53,Klf6,Ifit2,Slc25a37,Bcl6,Ifi209,Nfkb2,Kitl,Stip1,Spire1,Fcho2,Cxcl2,Pde4b,Plau,Ppfibp1,Nfkbiz,Atf3,Ccnd2,Ccl12,Slc7a11,Ifit1bl1,Ezr,Nfkbia,Hivep2,Dock4,Tmod3,Htra1,Akt3,Met,Ifi203,Rnf19a,Ltbp2,Birc3,Mier3,Ifit3,Smg7,Bmp2,Rhoc,Clcn5,Traf1,Cd180,Parp8,Ifi213,Ifi205,Abcc4,Fmnl2,Vegfc,Gng12,Dcbld2,Scyl2,Cd55,Cxcl10,Lox,Ifi208,Phlda1,Tnfsf15,Btg2,G3bp2,Gch1,Ifit1bl2,Nampt,Myo1b |
| 1.835e-19 | -43.14 | regulation of hydrolase activity | biological process | GO:0051336 | 1183 | 165 | 20694 | 1406 |
Rnf34,Ppp2r1b,Phactr4,Serpina3g,Aim2,Adora2a,Ccl7,Ppp1r14b,Ccl2,Oas3,Hdac1,Psmb9,Apaf1,Adrb2,Plaur,Nr4a1,Ppp1r15b,Birc3,Psmb8,S100a8,Serpinb2,Sipa1l1,Birc2,Elmod2,Hspa2,Tor1aip1,Antxr1,Dnaja1,Dennd1b,Pkp4,Fas,Dock4,Adap2,Spry2,Serpine1,Dnajb2,Pdgfrb,Myc,Ccl8,Htr2a,Oas1b,Ccl9,Rhoc,Nr1h3,Ppp4r2,Flt1,Oas1a,Ptafr,Vcan,Spred1,Serpina3f,Dnaja2,Serpinb6b,Mul1,Lpar1,Ripk2,Lrch1,Tnfsf15,Src,Cdc42ep2,Stat3,Bcl2l11,Casp4,Map4k4,Dock10,Map2k1,Casp1,Jak2,Prdx5,Stat1,Timp1,Spint2,Nlrc4,Uaca,Rin2,Rap1gap2,Crkl,Cd200,Ripk3,Cycs,Rictor,Serpinb9b,Ahsa1,Ranbp2,Nlrp3,Rgs14,Zc3hav1,Sele,Rgs1,Ccl4,Ric1,Sh3bp4,Syk,Tnf,Oasl1,Cx3cl1,Ccl3,Jun,Rffl,Fam162a,Arhgap26,Tnfsf10,Ift57,Ccl12,Rasgrp1,Casp8,Pml,Dnajb4,Cd40,Serpinb9,Ccl5,Tagap,Icam1,Nod1,Cdkn2d,Ppp1r15a,Malt1,Tor1aip2,Bcl6,Mmp25,Oas2,Tbc1d1,Agrn,Mefv,Cst7,Rcan1,C3,Psme2,Il6,Slpi,Ptgs2,Ppp6r1,Bcl2a1d,Cflar,Oasl2,Abr,Plscr1,Hspa1b,Plek,Tank,Rapgef2,Thbs1,Bmp2,Marf1,Rgs3,Ppp2r2a,F11r,Htr2b,Asap3,Tbc1d13,Tnfsf14,Ahr,Lyn,Cav1,Ppp2r5a,Oas1g,Sirt1,Mmp9,Psme1,Mdm2,Arf4,Ccl22,Ppp2r3a,Cnn3,Pmaip1 |
| 1.845e-19 | -43.14 | GO_REGULATION_OF_MAPK_CASCADE | MSigDB lists | GO_REGULATION_OF_MAPK_CASCADE | 612 | 117 | 15632 | 1249 |
Uchl1,Dusp5,Zc3h12a,Ptprj,Fpr1,Thbs1,Map4k4,Pik3r6,Pdgfb,Lif,Trim12c,Il1a,Icam1,Bmp2,Nod1,Mdfic,Daxx,Dusp1,Hsph1,Src,Cd40,Rgs14,Dusp8,Dbnl,Stk40,Nox1,Adrb2,Aida,Tnip1,Kdr,Igf1r,Ksr1,Cysltr2,Rasgrp1,Mapkapk2,Tlr6,Atf3,Ccl22,Htr2a,Prdx1,Angpt1,Tnfrsf14,Ccl12,Pik3r5,Map3k6,Flt1,Ezr,Jun,Psmd10,Prkce,Il6,Myc,Ccl2,Edn1,Spry2,Nod2,Ripk2,Crkl,Tlr3,Map3k8,Trib3,Adora2b,Irak2,Gcnt2,Kitl,Htr2b,Il1b,Dusp6,Ccl5,Gdf15,Ccr1,Map2k1,Osm,Pdgfrb,Fzd5,Rapgef2,Inhba,Cd74,Tab2,Ccl3,Irak3,Rgs3,Pdgfc,Tnf,Traf2,Errfi1,Glipr2,C3,Sema4c,Tlr9,Lyn,Trib1,Lpar1,Ccl4,Jak2,Vrk2,Dusp16,Tnfrsf1b,Ikbkg,Cav1,Fas,Mul1,Cx3cl1,Dusp14,Spred1,Syk,Gadd45b,Eif2ak2,Ptpn2,Dnaja1,Dusp2,Mid1,Dusp4,Pde5a,Gadd45g,Phlpp1,S1pr2 |
| 1.905e-19 | -43.10 | GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 852 | 146 | 15632 | 1249 |
Il27,Il15,Cd34,Tspo,Enpp4,Zc3hav1,Ddx60,Ubash3b,Pikfyve,Cdk5r1,Cx3cl1,Nr1h3,Mul1,Pla2g4a,Bnip3,Stap1,Scarf1,Eif2ak2,Spn,Syk,Sqstm1,Ptpn2,Jak2,Ccl4,Tlr9,Sema4c,C3,Trib1,Lpar1,Rab20,Lyn,Csf1,Fabp7,Rictor,S100a8,Ednrb,Nfkb1,Tnfrsf1b,Sema3c,Cav1,Nos2,Myd88,Ccl3,Tnfaip3,Prdm1,Aim2,Cd74,Sele,Dhx58,Tnf,H2-Q6,Bcl6,Ankrd17,Cxcl1,Plat,Il1b,Tlr3,Ripk2,Adora2b,Il18,Il12rb1,Cxcl2,Ccr1,Plek,Fcgr4,Ccl5,Gja1,Hopx,Fzd5,Pdgfrb,Osm,Map2k1,Atp6v1d,Serpine1,Plau,Chmp4b,Abr,Trim13,Nlrp3,Edn1,Ccl2,Il6,Nod2,Cxcl14,Cx3cr1,H2-Q4,Ifit1bl1,Ccl12,Zyx,Tnip1,Kdr,Trem1,Tnfsf4,Itpkc,Socs3,Tlr2,Sema4a,Adrb2,Mefv,Htra1,Sirt1,Smpdl3b,Pla2g7,Leng9,Met,Rabgef1,Birc3,Il10,Tnfsf14,Casp4,Nod1,Notch1,Hck,H2-Q7,Nfkbil1,Pml,Cd180,Hif1a,Ddx58,Calcrl,Stat2,Trim12c,Casp3,Psma6,Casp1,Swap70,Birc2,Cmklr1,Elmod2,Thbs1,Serpinb2,Plaur,Vegfc,Pf4,Ptger4,Larp1,Cd55,Zc3h12a,Traf3ip2,Uchl1,Ptgs2,Cxcl10,Il12b,Pdgfb,Ifit1bl2,Slc7a2 |
| 1.936e-19 | -43.09 | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_DN | MSigDB lists | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_DN | 170 | 54 | 15632 | 1249 |
Slc2a6,Cxcl2,Plek,Junb,Lcp2,Rrs1,Cxcl1,Nfkb2,Serpinb2,Il15ra,Zhx2,Keap1,Kdm6b,Zc3h12a,Rcan1,Nfkbie,Ehd1,Tnf,Dync1h1,Gypc,Rhbdf2,Relb,Hck,Tnfaip3,Plk3,Marcksl1,Lif,Icam1,Sertad3,Traf1,Ampd3,Abtb2,Nfkb1,Rel,Sik3,Fscn1,Tnip1,Rap2c,Ccl4,Tnfaip2,Cd82,Ebi3,Egr3,Tnip3,Acsl1,Ier3,Il6,Ezr,Gadd45b,Nfkbia,Trip10,Pilra,Sdc4,Lrp8 |
| 1.989e-19 | -43.06 | Measles | KEGG pathways | ko05162 | 135 | 50 | 7931 | 713 |
Stat3,Ifna5,Nfkbib,Ifnar1,Oas2,Oas3,Akt3,Hspa1b,Stat1,Nfkb1,Tyk2,Ifna4,Il1a,Il6,Stat2,Adar,Stat5a,Tnfaip3,Oas1b,Nfkbia,Ccne1,Irf7,Fas,Il2rg,Ikbke,Pik3cd,Ifih1,Oas1g,Ifna1,Ddx58,Tnfsf10,Tlr2,Tlr9,Rab9,Ccnd2,Ifna2,Myd88,Hspa1a,Jak2,Oas1a,Hspa2,Ccnd1,Il12b,Il1b,Fcgr2b,Tab2,Ifna6,Mx2,Eif2ak2,Ifnb1 |
| 1.989e-19 | -43.06 | Measles | KEGG pathways | mmu05162 | 135 | 50 | 7931 | 713 |
Il6,Stat2,Il1a,Ifna4,Tnfaip3,Stat5a,Adar,Oas1b,Oas3,Oas2,Ifnar1,Nfkbib,Ifna5,Stat3,Akt3,Tyk2,Nfkb1,Hspa1b,Stat1,Tab2,Fcgr2b,Il1b,Il12b,Ccnd1,Oas1a,Hspa2,Jak2,Hspa1a,Myd88,Eif2ak2,Mx2,Ifna6,Ifnb1,Il2rg,Fas,Irf7,Nfkbia,Ccne1,Pik3cd,Ikbke,Tlr2,Tnfsf10,Ddx58,Ifna1,Oas1g,Ifih1,Ifna2,Ccnd2,Rab9,Tlr9 |
| 2.056e-19 | -43.03 | SANA_RESPONSE_TO_IFNG_UP | MSigDB lists | SANA_RESPONSE_TO_IFNG_UP | 70 | 34 | 15632 | 1249 |
Tnfsf10,Gbp2b,Cxcl10,Mmp25,H2-Ab1,Ifi35,Rac3,Oas1g,Oas1a,Wars,Oas2,Ube2l6,H2-Aa,Cd274,Lap3,H2-Eb1,Samhd1,Lipg,Gbp3,Cx3cl1,Ifih1,Dtx3l,H2-Q7,Ddx60,Il18bp,Mlkl,Samd9l,Parp9,Parp14,Batf2,H2-Q6,Nlrc5,H2-Q4,Casp1 |
| 2.091e-19 | -43.01 | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | MSigDB lists | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | 176 | 55 | 15632 | 1249 |
Irf1,Tlr2,Dram1,Pim2,Ppa1,Stat1,Socs3,Tagap,Tnfaip2,Rgs1,C1rl,Lap3,Psmb8,Birc3,Ppp1r15b,Tnfrsf1b,Etv6,Nr1h3,Rars,Tnfrsf14,Tap1,Il15,Fbrsl1,Sod2,Tapbpl,Spata5l1,Il15ra,Rcl1,Glrx,Abcc4,Trafd1,Plcl2,Vcam1,Acsl5,Nfkb2,Cd274,Map2k1,Il12rb1,Wars,Slc2a6,Icam1,Gbp3,Dtx3l,Psmb10,Magohb,Mcm10,Aim2,Cd38,Mcmbp,Relb,Psmb9,Parp8,Nfkbie,Cebpd,Minpp1 |
| 2.214e-19 | -42.95 | GSE17721_0.5H_VS_8H_LPS_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_8H_LPS_BMDC_DN | 182 | 56 | 15632 | 1249 |
Slc37a3,Pkp4,Epsti1,Gca,Gtpbp2,Map3k8,Slamf8,Tmem229b,Smc5,Hmox1,Oas2,Tbc1d13,G3bp2,Rilpl1,Tmeff1,Vps54,Samsn1,Tshz1,Rgl1,Prpf38a,Mdfic,Rab3ip,1600014C10Rik,Traf5,Myd88,Rnf34,Gbp3,Dhx58,Hdac1,Fgl2,Lztfl1,Itpr1,Spryd7,Stat5a,Wdr43,Dusp16,Cd82,Denr,Mtmr14,Slpi,Atxn7l1,Irf8,Birc3,Atm,Pdk3,Tap1,Rbm43,P2ry14,Kat2b,Stxbp1,Cpd,Mllt6,Stard5,Dusp2,Mmp14,Sod2 |
| 2.301e-19 | -42.92 | GSE17721_LPS_VS_CPG_6H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_6H_BMDC_UP | 188 | 57 | 15632 | 1249 |
Hk1,Atm,Mov10,Flnb,Trim21,Akt3,Isg20,Ccrl2,Ifi35,Irf1,Rcn1,Rap2c,Sh3bgrl2,Lrrc8c,Lhx2,Tmem219,Itgav,Rab32,Dusp2,Stxbp1,Rars,Arl4a,Zbp1,Rbms2,Atp11b,Samhd1,Rbl1,Brd2,Snx10,Cacybp,Tbc1d13,Wars,Fam53c,Atp10a,Gpr85,Ptgs2,Nfkb2,Plat,Rsbn1,Sec24b,Dcbld2,Pkp4,Clmp,Phldb1,Hspa1a,Timp1,Dbnl,Tnfsf8,Rab9,Mafk,Acvr1,Ifih1,Arg2,Bfar,Prpf38a,Cd164,Rab3ip |
| 2.320e-19 | -42.91 | cellular response to lipopolysaccharide | biological process | GO:0071222 | 259 | 63 | 20694 | 1406 |
Cd80,Klrk1,Cxcl9,Il6,Ptafr,Cxcl10,Irgm2,Ripk2,Nos2,Nfkbil1,Plscr1,Casp1,Cmpk2,Cd86,Nfkbib,Jak2,Stat1,Acod1,Nfkb1,Cxcl3,Tnfaip3,Lyn,Prkce,Cxcl11,Irak2,Il18,Tnfrsf1b,Zc3h12a,Gfi1,Axl,Irf8,Nlrp3,Cd274,Il1b,Cxcl1,Tnf,Nfkbia,Pf4,Gbp2,Myd88,Ccl2,Il10,Cx3cr1,Tnfsf4,Ccl12,Arid5a,Gch1,Mtdh,Stap1,Nod2,Serpine1,Tnip3,Cxcl2,Ccl5,Pde4b,Cd14,Zfp36,Malt1,Fcgr4,Cd180,Nr1h3,Il1rn,Il12b |
| 2.805e-19 | -42.72 | STTTCRNTTT_IRF_Q6 | MSigDB lists | STTTCRNTTT_IRF_Q6 | 177 | 55 | 15632 | 1249 |
Evl,Bcor,Col4a2,Il27,Ciita,Zbp1,Tap1,Gsdmd,Psip1,Casz1,Cited2,Nod2,Il18bp,Ifnb1,Casp7,Ptk2,Ifit3b,Psmb8,Rnf31,Mov10,Ifit3,Trim21,Zeb1,Psme2,Med13,Xaf1,Etv6,Syne2,Psme1,Lif,Usp18,Ddx58,Pigv,Dtx3l,Psmb10,Isg15,Ifit2,Casp1,Psmb9,Ifi44,Slc15a3,Batf2,Ccnd1,Dhx58,Tapbp,Pcgf5,Tmem229b,Tapbpl,Cxcl10,Epsti1,5430427O19Rik,Nampt,Osm,Il12rb1,Uba7 |
| 2.846e-19 | -42.70 | negative regulation of nitrogen compound metabolic process | biological process | GO:0051172 | 2313 | 267 | 20694 | 1406 |
Plat,Ifi205,Casp3,Gja1,Itgav,Nfkb1,Relb,Zmynd15,Prkce,Psmd10,Cdk5r1,Nr4a3,Tnfsf14,Ccnd1,Mdm2,Rfx5,Btg2,Acp5,Mapkapk2,Trib3,Isg15,Hmga2,Il1b,Kdm4a,Il6,Dusp1,Hif1a,Sap30,Cflar,Ciita,Dusp8,Cd34,N4bp1,Cpeb4,Thbs1,Prnp,Nmral1,Zbtb5,Rel,Bmp2,Kmt5a,Eno1,Dnajb4,Zhx2,Notch2,Egr1,Pmepa1,Dusp4,Ifi214,Bcl6,Samsn1,Ppp1r15a,Ednrb,Cst7,Spred3,Gadd45b,Cgas,Txn1,Ubash3b,Dusp6,Rffl,Mdfic,Nck1,Zfp281,Met,Myd88,Acvrl1,Mafk,Rbbp8,Cdkn1a,Phf6,Ifi207,Arid5a,Crkl,Hat1,Sphk1,Cdyl2,Spint2,Errfi1,Prdx5,Bcor,Timp1,Tnfaip3,Trib1,Adar,Ifi211,Rnf139,Swap70,Rgs14,Mndal,Pdgfb,Lif,Serpina3f,Nr3c1,Src,Stat3,Hcls1,Klf2,Spen,Birc2,Dusp16,Dnajb2,Spry2,Nupr1,Myc,Ptpn2,Cebpd,Tle3,Nr1h3,Etv6,Kdm5b,Zeb1,Phactr4,Mecp2,Cenpj,Arid4a,Socs3,Plekhn1,Rnf34,Aebp2,Eif2ak2,Slfn1,Socs1,Hopx,Dcp2,Ppp1r14b,Mllt6,Ezr,Parp14,Birc3,Ddit4,Sco1,Sqstm1,Riox2,Ptch1,Tnip1,Ncoa7,Cav1,Lyn,Klf7,Ifi209,Ahr,Myadm,Sirt1,Mmp9,Etv3,Klf3,Ier3,Irf8,Hhex,Slpi,Nfil3,Tent4a,Atm,Bcl2a1d,Ahrr,Ifi213,Ptgs2,Mier3,Hsph1,Fam72a,Cd38,Timeless,Hspa1b,Fam129a,Dusp5,Cdyl,Dusp2,Rbl1,Larp1,Igf1r,Mtdh,Dr1,Wars,Cdkn2d,Jdp2,Kat2b,Uchl1,Rabgef1,Serpinb9,Aida,Arid5b,Max,Junb,Actb,C3,Parp3,Gclc,Cited2,Ric1,Fzd1,Tcf4,Jun,Daxx,Ifi204,Tnf,Plk3,Prdm1,Mxd1,Ikzf1,Angpt1,Noct,Pml,Atf3,Parp10,Caml,Ago3,Foxp4,Klf8,Il18,Zc3h12a,Gfi1,Pid1,Notch1,Serpinb9b,Spred1,Usp25,Znfx1,Ifi208,Parp9,Serpinb6b,Mvp,Nos2,Gbp4,Jarid2,Hap1,Ifi203,Ccne1,Nfkbie,Nmi,Tlk2,Ldlr,Ptprj,Dnaja1,Prkar2b,Tent2,Xrn1,Edn1,Serpinb2,Trim21,Radx,Serpine1,Nsd3,Gadd45g,Dtx3l,Irak3,Svbp,Zfp36,Ctla2a,Mov10,Atp2b4,Plpp3,Ets2,Hspa1a,Tspo,Adora2a,Serpina3g,Phlpp1,Hdac1,Irf1,Il10,Dach1,Tnfsf4,Plaur,Hinfp,Ppp1r15b,Nr4a1 |
| 2.949e-19 | -42.67 | GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_DN | 183 | 56 | 15632 | 1249 |
Nat2,Il6,Mmp14,Ccl12,Ifit1bl1,Hinfp,Prpf4,Tap1,Lrp8,St3gal5,Nfkbib,Med13,Trim21,Procr,Xaf1,Tdrd7,Psmb8,Lmo4,Ifit3,Ccl4,Cflar,Cdkn1a,Ell2,Oasl1,Ifi35,Kpna3,Ifit3b,Ifi44,Rsad2,Tlk2,N4bp1,Ifit2,P4ha2,Gpsm2,Ahsa1,Crlf3,Stau1,Jmjd6,Upp1,Maff,Stx11,Cxcl2,Stoml1,Map4k4,Ifit1bl2,Rgl1,Ccr1,Tap2,Ppp1r15a,Sp110,Ppp2r2a,Trafd1,Il1b,Plaur,Rnf19b,Osgin2 |
| 3.647e-19 | -42.46 | GO_REGULATION_OF_VIRAL_GENOME_REPLICATION | MSigDB lists | GO_REGULATION_OF_VIRAL_GENOME_REPLICATION | 71 | 34 | 15632 | 1249 |
Parp10,Ifi214,Isg15,Adar,Stau1,Ifi207,Notch1,Zc3hav1,Ifit1bl1,Tnf,Ifi213,Eif2ak2,Ifi209,Oas3,Ifi205,Rsad2,Ifnb1,Larp1,Oasl1,Oas1g,Zc3h12a,Ifi204,Fam111a,Tnip1,Ifit1bl2,Ccl5,Mndal,Isg20,Ifi211,Plscr1,Ifi208,Slpi,Oas1a,Ifi203 |
| 3.933e-19 | -42.38 | apoptotic process | biological process | GO:0006915 | 822 | 128 | 20694 | 1406 |
Ikbke,Ripk2,Mul1,Tnfsf15,Traf2,Xaf1,Ero1l,Nek6,1600014C10Rik,Lcn2,Casp1,Ggct,Bcl2l11,Dyrk2,Bcl2a1a,Phlda1,Casp4,Pim1,Usp53,Traf5,Hmox1,Inhba,Cycs,Tnfaip3,Prdx5,Jak2,Nlrc4,Uaca,Crkl,Notch1,Zc3h12a,Tnfrsf1b,Il18,Dnase1l3,Aim2,Serpina3g,Egln3,Rnf34,Ppp2r1b,Nr4a1,Ddit4,Map2k4,Xkr8,S100a8,Birc3,Irf1,Phlpp1,Apaf1,Nupr1,Fas,Hcar2,Csrnp1,Birc2,Sp110,Sav1,Etv6,Casp7,Fzd5,Gclm,Myc,Irak3,Gadd45g,Rmdn3,Ifit2,Cflar,Traf1,Bcl2a1d,Acvr1b,Il6,Atm,Ctsc,Casp2,Tmem219,Plscr1,Tax1bp1,Spn,Tnfsf14,Psmd10,Cav1,4930453N24Rik,Nfkb1,Kremen1,Itgav,Itpr1,Gja1,Casp3,Ikbkg,Sqstm1,Tlr3,Hk2,Il1b,Pim3,Trib3,Dram1,Pmaip1,Ier3,Sirt1,Arel1,Tnf,Plk3,Daxx,Il1a,Ifi204,Fam162a,Kitl,Jun,Rffl,Sod2,Bcl2a1b,Tpx2,Asah2,Pim2,Cdkn1a,Pml,Ciapin1,Casp8,Myd88,Tnfsf10,Ift57,Srgn,Serpinb9,Nod1,Traf3ip2,Gadd45b,Gclc,Ppp1r15a,Malt1,Bnip3 |
| 4.022e-19 | -42.36 | GO_REGULATION_OF_SYMBIOSIS_ENCOMPASSING_MUTUALISM_THROUGH_PARASITISM | MSigDB lists | GO_REGULATION_OF_SYMBIOSIS_ENCOMPASSING_MUTUALISM_THROUGH_PARASITISM | 190 | 57 | 15632 | 1249 |
Larp1,Zc3h12a,Oas1g,Il12b,Ifit1bl2,Ccl5,Tap2,Trim26,Ifi208,Parp10,Pml,Trim12c,Isg15,Notch1,Stau1,Mdfic,Ifi213,Tnf,Oas3,Ifi205,Ifi209,Hdac1,Rsad2,Stat1,Oasl1,Ifi204,Fam111a,Polr2g,Tnip1,Ccl4,Irf8,Il10,Cav1,Mndal,Ifi211,Isg20,Trim14,Trim21,Slpi,Plscr1,Oas1a,Ifi203,Trim13,Ifi214,Adar,Ifi207,Chmp4b,Zc3hav1,Tap1,Eif2ak2,Ifit1bl1,Bcl2l11,Itgav,Sqstm1,Jun,Ifnb1,Pcx |
| 4.022e-19 | -42.36 | RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | 118 | 44 | 15632 | 1249 |
Icam1,Apaf1,Relb,Tnfaip3,Cd14,Klf6,N4bp1,Mdm2,Cebpd,Stat3,Cish,Trib3,Map3k8,Hp,Rnf19b,Cxcl1,Nfkb2,Thbs1,Plk2,Pde4b,Junb,Dusp6,Btg2,Rab10,Cx3cl1,Nfkbiz,Atf3,Mapkapk2,Stxbp1,Hivep2,Nfkbia,Sqstm1,Edn1,Irf1,Dusp16,Cdkn1a,Tnip1,Lcn2,Birc3,Rnf19a,Rhou,Csf1,Plscr1,Nfkbib |
| 4.299e-19 | -42.29 | Toll-like receptor signaling pathway | KEGG pathways | ko04620 | 99 | 42 | 7931 | 713 |
Nfkb1,Jun,Ifna2,Tlr9,Stat1,Ccl3,Map3k8,Cd40,Ifna1,Tlr2,Akt3,Cd80,Ccl4,Tlr3,Pik3cd,Ikbke,Cxcl11,Cd86,Casp8,Tnf,Ifnar1,Cxcl10,Nfkbia,Ifna5,Irf7,Tlr1,Cd14,Ifnb1,Tlr6,Fos,Ccl5,Map2k4,Map2k1,Cxcl9,Ifna6,Il12b,Il1b,Tab2,Ikbkg,Ifna4,Myd88,Il6 |
| 4.299e-19 | -42.29 | Toll-like receptor signaling pathway | KEGG pathways | mmu04620 | 99 | 42 | 7931 | 713 |
Casp8,Cd86,Cxcl11,Ikbke,Pik3cd,Tlr3,Cd80,Ccl4,Ifna5,Irf7,Nfkbia,Tnf,Ifnar1,Cxcl10,Ccl3,Tlr9,Stat1,Jun,Ifna2,Nfkb1,Akt3,Tlr2,Map3k8,Cd40,Ifna1,Ifna6,Cxcl9,Map2k1,Il6,Ikbkg,Myd88,Ifna4,Tab2,Il12b,Il1b,Ifnb1,Cd14,Tlr1,Map2k4,Ccl5,Fos,Tlr6 |
| 4.954e-19 | -42.15 | regulation of cytokine secretion | biological process | GO:0050707 | 213 | 56 | 20694 | 1406 |
Arg2,Il6,Tnfsf15,Ripk2,Src,Clec5a,Cd34,Casp4,Casp1,Ifnar1,Tlr6,Htr2b,Tlr2,Clec4e,Cd200,Ddx58,Osm,Il4ra,Tnfaip3,Lyn,Tnfrsf14,Tnfrsf1b,Zc3h12a,Clec4n,Nlrp3,Cd274,Il1b,Lgals9,Ptger4,Syk,Il1a,Ccl3,Tnf,Socs1,Mapkbp1,Cx3cl1,Aim2,Angpt1,Tlr9,Tnfsf4,Rasgrp1,Arid5a,Ezr,Il10,Pml,Ifih1,Fgr,Hk1,Rgcc,Rabgef1,Srgn,Nod2,Cd14,Fzd5,Gsdmd,Tlr1 |
| 5.196e-19 | -42.10 | GSE17721_12H_VS_24H_CPG_BMDC_UP | MSigDB lists | GSE17721_12H_VS_24H_CPG_BMDC_UP | 185 | 56 | 15632 | 1249 |
Tfec,Ptges,Kitl,Clic4,Slamf8,Usp42,Ttc39b,Ptger4,Psmb6,Snx2,G3bp2,Uba7,Tbc1d13,Rgl1,Slc31a2,Brwd3,Rhoc,1600014C10Rik,Lipg,Il1a,Ifih1,Rsad2,Casp3,Phgdh,Gbp9,Gbp4,Ccdc86,Batf2,Carhsp1,Psmb9,Cd40,Phldb1,Wdr43,Tnfaip2,Fam20c,Trib1,Asb13,Hmgcs1,Endod1,Usp12,Met,Zfp36,Mov10,Chmp4b,Slc28a2,Ciita,F10,Il15,Pnpt1,Ciapin1,Fas,Ppp2r5a,Ccl2,Spic,Msr1,Ezr |
| 5.415e-19 | -42.06 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | 162 | 52 | 15632 | 1249 |
Prkar2b,Ust,Ifit3b,Stat1,Oasl1,Hmgcs1,Egln3,Xaf1,Oas1a,Flnb,Zeb1,Gem,Ifit3,Cav1,Mfap3l,Angpt1,Il15,Rtp4,Arl4a,Palld,Ddx60,Dusp4,Samd9l,Gpr18,Dhrs9,Eif2ak2,Ifit1bl1,Sp110,Cmpk2,Epsti1,Thbs1,Cxcl10,Ptgs2,Oas1g,Atp10a,AA467197,Oas2,Irf7,Hopx,Ifit1bl2,Cd38,Arg2,Isg15,Ifih1,Ddx58,Usp18,Mcoln2,Rsad2,Rbpms,Ifi44,Oas3,Ifit2 |
| 5.541e-19 | -42.04 | GO_RESPONSE_TO_LIPID | MSigDB lists | GO_RESPONSE_TO_LIPID | 836 | 143 | 15632 | 1249 |
Ptger4,Ldha,Zc3h12a,Ptgs2,Pim1,Ptafr,Serpinb9,Cxcl10,Il12b,Lox,Il1rn,Thbs1,Gng12,Pf4,Cmpk2,Junb,Gch1,Cnp,Cd86,Pdgfb,Csf3,Nfkbil1,Hif1a,Icam1,Cd180,Sphk1,Socs1,Tnfrsf8,Daxx,Notch1,Hck,Src,Axl,Dusp1,Ifnar1,Casp1,Cd40,Rbbp8,Casp3,Nr3c1,Mdm2,Acvr1,Ccnd1,Tnfsf4,Socs3,Acsl1,Tlr2,Adrb2,Gfi1,Pdk3,Ccne1,Il10,Irf8,P2ry2,Ptch1,Abr,Lrp8,Mapkapk2,Nlrp3,Il4ra,Plau,Tnfrsf14,Cx3cr1,Nfkbia,Ccl12,Fos,Jun,Edn1,Peli1,Il6,Prkce,Il18bp,Nqo1,Hmox1,Ripk2,Il18,Nr4a3,Cxcl1,Vcam1,Nfkb2,Irak2,Ptges,Il1b,Pde4b,Ccl5,Fosb,Serpine1,Pdgfrb,Inhba,Mmp13,Fzd1,Cxcl2,Fabp3,Cd14,Cd38,Irak3,Tnfaip3,Tnf,Tnc,Stat3,Sele,Errfi1,Mecp2,Hmgcs1,Mtdh,Ptgir,C3,Lpar1,Tnip3,Trib1,Lyn,Jak2,Pmepa1,Cdkn1a,S100a8,Tnfrsf1b,Rnf14,Nfkb1,Ednrb,Cav1,Pid1,Nos2,Casp8,Slpi,Med13,Nfkbib,Fas,Cdkn2d,Sdc1,Nr1h3,Il15,Cd80,Tspo,Ahr,Eif2ak2,Nr4a1,Ass1,Dnaja1,Cited2,Pla2g4a,Stap1,Mmp14,Ifnb1 |
| 5.899e-19 | -41.97 | ELVIDGE_HYPOXIA_BY_DMOG_UP | MSigDB lists | ELVIDGE_HYPOXIA_BY_DMOG_UP | 119 | 44 | 15632 | 1249 |
Klf6,P4ha2,Slc2a1,Itpr1,Sat1,Nr3c1,Ccng2,Gys1,Gja1,Gdf15,Serpine1,Daam1,Phlda1,Tmeff1,Ddit4,Maff,Hk2,Lox,Tgfbi,Adora2b,Ak4,Pim1,Pgk1,Glrx,Vegfc,Plaur,Plac8,Jun,Cited2,Fos,Bnip3,Egr1,Atf3,Gbe1,Pfkfb3,Klf7,P4ha1,Eno2,Cav1,Isg20,Met,Egln3,Nfil3,Fam162a |
| 5.929e-19 | -41.97 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN | 168 | 53 | 15632 | 1249 |
Ccnd2,Arl4a,Ddx60,Tap1,Phf11c,Slamf7,Adar,Phf11a,B4galt4,Ptpn2,Eif2ak2,Rnf114,Optn,Edn1,Phf11d,Ifit3b,Trem1,Ifit3,Casp4,Pdk3,Syne2,Xaf1,Csf1,Trim21,Isg20,Hif1a,Sphk1,Psmb10,Psme1,Rgs3,Gbp2,Batf,Psmb9,Mtus1,Phf11b,Ifit2,Stat5a,Sp140,Rsad2,Stat3,Arid5b,Herc6,Parp3,Zc3h12a,Sp110,Nfkb2,Cnp,Irf7,G3bp2,Inhba,Oas2,Parp12,Ube2l6 |
| 6.207e-19 | -41.92 | regulation of transcription, DNA-templated | biological process | GO:0006355 | 2811 | 308 | 20694 | 1406 |
Traf5,Ripk3,Hmgn3,Cd200,Maff,Ddx58,Irf7,Trib1,Tnfaip3,Inhba,Nlrc4,Tlr6,Jak2,Prdx5,Bcor,Stat1,Tcea1,Sphk1,Hat1,Nlrp3,Mndal,Rgs14,Pou2f2,Ifi211,Sp140,Plac8,Wdr43,Batf2,Psma6,Ptafr,Mafg,Pdgfb,Lif,Map2k1,Hcls1,Stat2,Tfec,Src,Hck,Stat3,Egr3,Peli1,Nr3c1,Aff1,Nupr1,Rhoq,Csrnp1,Klf2,Ifrd1,Spen,Tle3,Nr1h3,Etv6,Zeb1,Kdm5b,Fosb,Fzd5,Ptpn2,Dcp1a,Cebpd,Plagl2,Myc,Slfn1,Plagl1,Eif2ak2,Hopx,Ell2,Stat5a,Aebp2,Arid4a,Mecp2,Mllt6,Ezr,Maml2,Batf,Spic,Nfkbia,Adrb2,Pf4,Tlr9,Med21,Slc9a1,Cdk5r1,Psmd10,Keap1,Nr4a3,Ccnd1,Nfkb1,Relb,Crlf3,Zmynd15,Ifnar1,Ikbkg,Tlr3,Ifi205,Hmga2,Il1b,Tal2,Tet2,Fubp1,Pttg1,Trib3,Mdm2,Rfx5,Btg2,Jag1,Tnfrsf8,Mamld1,Cflar,Sap30,Ciita,Acvr1b,Hif1a,Perm1,Nfkb2,Kdm4a,Il6,Bmp2,Zbtb5,Rel,Prnp,Nmral1,Prdm9,Lhx2,Rgcc,Egr1,Notch2,Zhx2,Brd2,Eno1,Dnajb4,Kmt5a,Kdm6b,Txn1,Agrn,Ppp1r15a,Ednrb,Ifi214,Gdf15,Bcl6,Mdfic,Cx3cl1,Cacna1d,Kdr,Egr2,Nlrc5,Fcgr2b,Etv5,Arid5a,Nampt,Zfp513,Phf6,Ifi207,Met,Myd88,Mafk,Acvrl1,Nck1,Zfp281,Tlr2,Hmox1,Pim1,Foxp4,Klf8,Nfkbib,Notch1,Gfi1,Pid1,Il18,Zc3h12a,Irak2,Gbp4,Rnf14,Znfx1,Ifi208,Parp9,Ripk2,Hlx,Htra1,Traf2,Nfkbie,Il18rap,Tnfsf8,Jarid2,Ifi203,Ccne1,Csf3,Hivep2,Nfkbil1,Trim26,Lrp8,Nsd3,Nfkbid,Hmga1,Nod2,Resf1,Edn1,Trim21,Hivep3,Med13,Sav1,Zfp36,Irf4,Dtx3l,Irak3,Adora2a,Aim2,Ets2,Cmklr1,Atp2b4,Plpp3,Tnfsf4,Hinfp,Acvr1,Irf2,Nr4a1,Il10,Dach1,Cx3cr1,Irf1,Hdac1,Ahr,Pbx1,Ifi209,Osm,Tnip1,Ncoa7,Cav1,Klf7,Ptch1,Acod1,Lmo4,Helz2,Sqstm1,Hhex,Irf8,Trim13,Sirt1,Etv3,Klf3,Arf4,Ahrr,Ifi213,Ier2,Traf1,Fos,Bcl9,Casz1,Klf6,Nfil3,Atm,Nfxl1,Plscr1,Dusp5,Mier3,Hsph1,Timeless,Tax1bp1,Cd38,Icam1,Trim14,Ifnb1,Nod1,Kat2b,Jmjd6,Jdp2,Dr1,Tshz1,Phip,Psip1,Cd40,Rbl1,Igf1r,Mycl,Mtdh,Gclc,Cd74,Pou3f1,Junb,Malt1,Arid5b,Rnf31,Max,Il1a,Ccl3,Daxx,Ifi204,Plk3,Tnf,Fzd1,Jun,Pcgf5,Tcf4,Sod2,Bambi,Cited2,Syk,Stat4,Taf4b,Parp10,Sertad3,Pim2,Brwd3,Pml,Atf3,Ikzf1,Prdm1,Mxd1 |
| 6.349e-19 | -41.90 | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_DN | 174 | 54 | 15632 | 1249 |
Ddx60,Xrn1,Fpr2,Phf11a,Slamf7,Il15,Phf11c,Sod2,Dnaja1,Pla2g4a,Parp9,Dusp4,Vcan,Ppa1,Cd200,Casp7,Ebi3,Phf11d,Znrf1,Ppfibp2,Birc3,Abtb2,Psme2,Met,Xaf1,Stat4,Isg15,Fabp3,Zfp281,Mapkbp1,Batf,Cd38,Phf11b,Swap70,Itgb8,Rab21,Dhx58,Psma6,Fndc3a,Herc6,Il12b,Ak4,4930453N24Rik,Trafd1,Sp110,Il15ra,Cdyl,Txn1,Fubp1,Lad1,Tap2,Cd274,Tnfsf15,AA467197 |
| 6.610e-19 | -41.86 | GSE2706_2H_VS_8H_LPS_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_LPS_STIM_DC_DN | 157 | 51 | 15632 | 1249 |
Ddx60,Tap1,Znfx1,Trip10,Nlrc5,Plac8,Eif2ak2,Optn,Cnot4,Dusp4,Aida,Lyn,Ifi35,Ebi3,Casp7,Tnfsf4,Ppa1,Ppfibp2,Jak2,Mov10,Nfkb1,Oas1a,Plscr1,Psme2,Stat2,Zfp281,Dtx3l,Trim12c,Gbp3,Aim2,Cd38,Sp140,Dhx58,Itgb8,Oas1g,Dusp5,Pcgf5,Epsti1,Il15ra,Ppp2r2a,Trafd1,Tap2,Ppm1k,Cnp,4930523C07Rik,Ccl5,Map4k4,Tbc1d13,AA467197,Ube2l6,Nmi |
| 6.857e-19 | -41.82 | GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | MSigDB lists | GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | 146 | 49 | 15632 | 1249 |
Egr1,Nfkbiz,Etv3,Bcl2l11,Nfkbia,Nr4a1,Gadd45b,Gramd1a,Gpr18,Fos,Dusp2,Ctsc,Parp14,Tra2a,Psd,Etnk1,Ier3,Mefv,Trib1,Tagap,Nfkb1,Birc3,Rel,Cd69,Rnf19a,Icam1,Batf,Tnfaip3,Relb,Cish,Egr2,Zc3h12a,Ptger4,Nr4a3,Cxcl10,Il12b,Fpr1,Map3k8,Arid5b,Nfkb2,Plcl2,Zhx2,Cd274,Samsn1,Ppp1r15a,Plk2,Arl5b,Stx11,Nfkbid |
| 6.967e-19 | -41.81 | GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_DN | 192 | 57 | 15632 | 1249 |
Clic4,Cldnd1,Rnf19b,Slc31a1,Oas1g,Tgfbi,Pim1,Cxcl10,Ext1,Noc4l,Gja1,Rrs1,Rnf34,Cd164,Notch1,Mcoln2,Icam1,Zfp281,Hif1a,Rhoq,Dusp1,Txnrd1,Casp1,Bcl6,Slc2a1,Jak2,Rbms1,Ccl4,Stat1,Il13ra1,Rcn1,Gpd2,Plscr1,Psme2,Oas1a,Pdk3,Psmb8,Ikbkg,Casp4,Gbp7,Cd34,Ahr,Tle3,Fas,Rars,Atf3,Cdkn2d,Il4ra,Slc30a1,Tor1aip2,Fcgr2b,Pla2g4a,Il18bp,Gadd45g,Hivep2,Mrpl52,Ptpn2 |
| 7.984e-19 | -41.67 | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP | 169 | 53 | 15632 | 1249 |
Ptgs2,Nsmaf,Dusp5,Plaur,Snapc1,Cxcl1,Cldnd1,Txn1,Inhba,Ddit4,Phlda1,Tnfsf15,Upp1,St3gal6,Csrnp1,Homer1,Tnf,Dusp1,Usp53,Txnrd1,Mafk,B3gnt5,Phgdh,Nr3c1,Egr2,Pnp2,Trib1,Mafg,Rab20,Egr3,Ell2,Cdkn1a,Rgs1,Tnfsf14,Gem,Rabgef1,Usp12,Rnf19a,Egln3,Csf1,Srxn1,Sgms2,Atf3,Egr1,Ets2,Jun,Nr4a1,Gadd45b,Dusp4,Gclm,Spry2,Edn1,Dusp2 |
| 7.984e-19 | -41.67 | GSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_DN | MSigDB lists | GSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_DN | 169 | 53 | 15632 | 1249 |
Ddx60,Palld,Phf11a,Atp2b4,Phf11c,Eif2ak2,Ifit1bl1,Slc7a11,Ets2,Edn1,Oasl1,Lpar1,Phf11d,Ifit3b,Zcchc2,Ppfibp2,Ifit3,Isg20,Trim14,Plscr1,Oas1a,Tdrd7,Ier2,Pml,Ddx58,Usp18,Trim12c,Isg15,Ifih1,Myd88,Cd164,Phf11b,Ifit2,Src,Oas3,Ifi44,Tlk2,Rsad2,Smox,Herc6,Hmox1,Oas1g,Lox,Gtpbp2,Tnfsf10,Sp110,Ifit1bl2,Irf7,Ext1,Trim26,Bst1,Oas2,Parp12 |
| 8.216e-19 | -41.64 | ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP | 437 | 93 | 15632 | 1249 |
Nampt,Tmem26,Nfkbid,Csf3,Maff,Pdgfb,Btg2,Slc2a6,Scn1b,Ptgs2,Cxcl10,Il12b,Rnf19b,Kdm6b,Cd55,Zc3h12a,Plaur,Zhx2,Bambi,Serpinb2,Src,Ehd1,Gpr84,Casp3,Icam1,Il1a,Traf1,Mdfic,Relb,Cd83,Irf8,Zc3h12c,Ccrl2,Jag1,Tlr2,Ier3,Acsl1,Clcf1,Tmem67,Tnfaip2,Jun,Nfkbia,Kremen1,Edn1,Il6,Sgms2,Slc28a2,Hopx,Ppp1r15a,Serpine1,Car13,Rapgef2,Cxcl2,Icosl,Il18,Ripk2,Gng4,Snn,Il1b,Cxcl1,Kitl,Nfkb2,Irak2,Stat5a,Tnf,Zswim4,Itgb8,Plk3,Tnfaip3,Rel,Gem,Nfkb1,Usp12,Csf1,Ppp4r2,Itga9,Dram1,Dtx2,Mob3c,Fscn1,Cd82,Ccl4,Ldlr,Trip10,Trim36,Rapgef5,Fpr2,Cyth3,Pikfyve,Sdc4,Pim3,Cd80,Clec4e |
| 8.852e-19 | -41.57 | GSE17721_0.5H_VS_4H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_POLYIC_BMDC_DN | 181 | 55 | 15632 | 1249 |
Gsr,Rsad2,Dhx58,Lztfl1,Carhsp1,Nr3c1,Cst7,N4bp1,Gbp2,Cd38,Stau1,Rnf34,Bfar,Fabp3,Irf2,Itga4,Oas2,Ppp1r15a,Plk2,Gch1,Nampt,Keap1,Ralgds,Cldnd1,Chic2,Smc5,Smox,Vcan,Ppp2r5a,Stard5,Znfx1,Ccl12,Sqstm1,Nfkbia,Rbm43,P2ry14,Usp25,Abr,Atf3,Tdrd7,St3gal5,Srxn1,Csf1,Plekha2,Adap2,Nfkb1,Pdk3,Cdkn1a,Vrk2,Dusp16,Plekhn1,Kdr,Gfpt1,Ms4a6d,Endod1 |
| 9.068e-19 | -41.54 | GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_DN | MSigDB lists | GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_DN | 187 | 56 | 15632 | 1249 |
Gbp9,Gbp4,Cish,Batf2,Gpr84,Rsad2,N4bp1,Phldb1,Stat5a,P2ry13,Gnb4,Daxx,Pml,Nupr1,Ch25h,Mxd1,Dtx3l,Nrp2,Ube2l6,Uba7,Oas2,Txn1,Vps54,Irf7,Plk2,Slfn4,Ikbke,Slfn3,Dusp28,Tfec,Oas1g,Pcgf5,Herc6,St7,Fpr1,Spata5l1,Clec5a,Il18bp,Cox17,Slc28a2,Samhd1,Tap1,Rars,Ccnd2,Rasgrp1,Cd69,Smpdl3b,Oas1a,Ppp1r15b,Ankib1,Kdr,Gfi1,Trem1,Dgkh,Rab20,Irf1 |
| 9.068e-19 | -41.54 | GSE8835_HEALTHY_VS_CLL_CD4_TCELL_UP | MSigDB lists | GSE8835_HEALTHY_VS_CLL_CD4_TCELL_UP | 187 | 56 | 15632 | 1249 |
H2-Q4,Ezr,Gclm,Katna1,Cnot4,Dusp4,Bcor,Stxbp1,Trim13,Prnp,Ccnd2,Sgcb,Il15,Fbxo4,Rbm43,Dusp14,Ifit3,Hdc,St3gal5,Oas1a,Hat1,Cd69,Syne2,Ptk2,Oasl1,Uaca,Ddx4,Fam111a,Ifit3b,Rab20,Actb,Pmepa1,Ifit2,N4bp1,Casp1,H2-Q6,Gpr84,Ogfrl1,Ccnd1,H2-Q7,Spata13,Crlf3,Rgs3,Daxx,Txn1,Samsn1,Sap30,Gbgt1,Eya4,Mmp13,Xkr8,Atp10a,Oas1g,Trib3,Pkp4,Cmpk2 |
| 9.091e-19 | -41.54 | positive regulation of cell differentiation | biological process | GO:0045597 | 1099 | 155 | 20694 | 1406 |
Tlr2,Trib1,Inhba,Jak2,Stat1,Sphk1,Crkl,Scarf1,Notch1,Nlrp3,Trip10,Rgs14,Gfi1,Tnfrsf1b,Zc3h12a,Il18,Gpc1,Ripk2,Hlx,Mul1,Lpar1,Flt1,Scn1b,Cxcl9,Lif,Hcls1,Eif4g2,Map2k1,Hap1,Ccne1,Egr3,Gcnt2,Stat3,Csf3,Gpr68,Sema3c,Nr3c1,Lrp8,Csf1,Il15,Serpine1,Carmil1,Nfkbid,Triobp,Edn1,D16Ertd472e,Spen,S1pr2,Zeb1,Rac3,Sav1,Mmp14,Ptk2,Cebpd,Zfp36,Pde5a,Myc,Ccl8,Htr2a,Socs1,Ap3b1,Pdpn,Hopx,Tspo,Ehd1,Stat5a,Glipr2,Cmklr1,Kif3c,Socs3,Abcb1a,Mecp2,Vegfc,Ptger4,Acvr1,Tnfsf4,Cx3cr1,Rab21,Irf1,Hdac1,Pf4,Myadm,Tnfsf14,Clcf1,Lyn,Il4ra,Itpr1,Ptch1,Dbnl,Nfkbiz,Pik3r6,Il1b,Cd83,Isg15,Il15ra,Lgals9,Fubp1,Axl,Sirt1,Fam20c,Ptgs2,Jag1,Mmd,Cflar,Il2rg,Fos,Hif1a,Acvr1b,Cyfip1,Il6,Kdm4a,Bmp2,Tnfsf9,Rapgef2,Cd34,Ccl5,Rgcc,Notch2,Kat2b,Msr1,Nlgn2,Igf1r,Il12b,Cd74,Mark2,Malt1,Pdlim7,Junb,Bcl6,Gdf15,Tnf,Cx3cl1,Ccl3,Ifi204,P2ry2,Jun,Tcf4,P2ry12,Sod2,Kitl,Fzd1,Kdr,Bambi,Syk,H2-Aa,Etv5,Rasgrp1,Ccr1,Casp8,Acvrl1,Ikzf1,Met,Noct,Nck1,Prdm1 |
| 9.140e-19 | -41.54 | HALLMARK_IL2_STAT5_SIGNALING | MSigDB lists | HALLMARK_IL2_STAT5_SIGNALING | 193 | 57 | 15632 | 1249 |
Lrrc8c,Nfil3,Igf1r,Adam19,Sh3bgrl2,Odc1,Plscr1,Csf1,Ptch1,Il10,Irf8,P4ha1,Tnfrsf1b,Ccne1,Ahr,Il4ra,Arl4a,Ccnd2,Plagl1,Prnp,Mapkapk2,Nfkbiz,Myc,Abcb1a,Irf4,Cyfip1,Itgav,Gadd45b,Tnfsf10,Cxcl10,Map3k8,Ttc39b,Pim1,Maff,Hk2,Phlda1,Hopx,Cd86,Bmp2,Tnfrsf8,Cd83,Batf,Sell,Socs1,Gbp3,Traf1,Rhoh,Lif,Mxd1,Glipr2,Fgl2,Pnp2,Cish,Casp3,Swap70,Cst7,Klf6 |
| 9.889e-19 | -41.46 | KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | MSigDB lists | KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | 243 | 65 | 15632 | 1249 |
Tnfsf8,Acvrl1,Acvr1,Ifnar1,Tnf,Cd40,Csf3r,Bmp2,Tnfrsf8,Ccl3,Ifna2,Pdgfc,Lif,Il1a,Tnfsf15,Ifna6,Pdgfb,Cxcl2,Inhba,Il12rb1,Csf3,Ccl5,Ccr1,Pdgfrb,Osm,Tnfsf10,Kitl,Cxcl1,Il1b,Pf4,Il15ra,Vegfc,Il12b,Cxcl10,Il2rg,Il18,Il6,Ccl2,Ccr3,Ifna5,Ifnb1,Cxcl14,Ccl12,Flt1,Cx3cr1,Il15,Ifna1,Tnfrsf14,Fas,Il4ra,Cx3cl1,Ccl22,Csf1,Il18rap,Met,Tnfrsf1b,Il10,Tnfsf14,Ccl4,Kdr,Clcf1,Xcr1,Il13ra1,Tnfsf4,Acvr1b |
| 9.933e-19 | -41.45 | IRF7_01 | MSigDB lists | IRF7_01 | 224 | 62 | 15632 | 1249 |
Casp7,Kpna3,Oasl1,Pik3cd,Agpat4,Ubr4,Mov10,Trim21,Xaf1,Ddx60,Evl,Cyth3,Il27,Adar,Tap1,Rbl1,Fos,Casz1,Optn,Phlpp1,Il18bp,Ifnb1,Pcgf5,Tmem229b,Map3k8,Nr4a3,Cxcl10,Lox,Epsti1,Zhx2,Sp110,Ppp2r2a,5430427O19Rik,Cdyl,Col11a2,Flrt2,Osm,Sipa1l1,Tnfsf15,Parp12,Stx11,Uba7,Irf2,Psme1,Lif,Usp18,Ddx58,Isg15,Dtx3l,Socs1,Pdgfc,Parp8,Ifit2,Armcx6,Psmb9,Bcl6,Zmynd15,Sat1,Pde1b,Batf2,Tlk2,Tapbp |
| 9.950e-19 | -41.45 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_DN | 164 | 52 | 15632 | 1249 |
Cdkn1a,Dusp16,Phf11d,Ifi204,Stat1,Il18rap,Ifi203,Sirt1,Oas1a,Isg20,Ksr1,Ifi211,Lap3,Lmo4,Mndal,Irf8,Phf11c,Ifi207,Phf11a,P2ry14,Ifi214,Kat2b,Fas,Atf3,Parp9,Pdpn,Slc44a1,Parp14,Sod2,Pik3r5,Dhrs9,Pf4,Epsti1,Plat,Map3k8,Oas1g,Rapgef2,Wars,Ifi208,Irf7,Map4k4,Pde4b,Sla,Slc39a13,Tab2,Mcoln2,Ifi44,Ifi209,Ifi205,Sp140,Ifi213,Phf11b |
| 1.106e-18 | -41.35 | GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | MSigDB lists | GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 749 | 132 | 15632 | 1249 |
Phip,Nlrp3,Lrp8,Egr1,Atp2b4,Prdx1,Plau,Gng11,Pde3b,Fos,Cx3cr1,Ezr,Nfkbia,Agrn,Ccl12,Nod2,Il18bp,Nqo1,Edn1,Il6,Prkce,Tlr2,Tnfsf4,Igf1r,Prkar2b,Socs7,Gfi1,Gna15,Irf8,Il10,Casp4,P2ry2,Ptch1,Pdk3,Sirt1,Calcrl,Icam1,Hif1a,Cd180,Sphk1,Socs1,Agtrap,Nfkbil1,Hck,Nod1,P2ry12,Cd40,Axl,Src,Mdm2,Rhoq,Ptgs2,Pim1,Ptafr,Il12b,Cxcl10,Kdm6b,Ptger4,Zc3h12a,Gng12,Cmpk2,Cd86,Klf2,Nampt,Csf3,Pdgfb,Kat2b,Irs2,Nr1h3,Cdk5r1,Fas,Il15,Cd80,Tspo,Ptpn2,Klf3,Nr4a1,Ass1,Sod2,Ifnb1,Bnip3,Stap1,Lpar1,Tnip3,Lyn,Cpeb4,Hmgcs1,Mtdh,Max,Ptk2,Gfpt1,Jak2,Cav1,Pid1,Nos2,Nfkb1,Tnfrsf1b,Ednrb,Il18rap,Slc9a1,Zeb1,Nfkbib,Pdgfc,Tnfaip3,Gnb4,Cd14,Traf2,Tnf,Klf6,Stat5a,Errfi1,Prdx5,Tnc,Stat3,Trib3,Il18,Nr4a3,Ripk2,Gng4,Htr2b,Il1b,Irak2,Ppp1r15a,Atp6v1d,Serpine1,Pde4b,Ccl5,Rapgef2,Inhba,Sh3bp4,Fzd1,Rab10 |
| 1.173e-18 | -41.29 | GSE17721_0.5H_VS_12H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_12H_POLYIC_BMDC_DN | 182 | 55 | 15632 | 1249 |
Ccl5,Snx10,Vps54,Cacybp,Tyk2,Snx2,Ripk2,Serpinb9,Ralgds,Mitd1,Gca,Hcar2,Pkp4,Epsti1,Plekhf2,Phldb1,P2ry12,Homer1,Atp13a1,Nupr1,Itga4,Gbp3,Fabp3,F11r,Traf5,Rnf34,Bfar,Gbp2,Plagl2,Stau1,Ccne1,Ppp1r15b,Birc3,Cep350,Syne2,Tdrd7,Dtx2,Mtmr14,Ddx4,Ms4a6d,Arf4,Lhx2,Esd,Sqstm1,Hmga1,Znfx1,Ppp2r5a,Vcan,Kremen1,Gmppb,Kat2b,Angpt1,Olr1,Slc28a2,Me1 |
| 1.195e-18 | -41.27 | GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 1394 | 204 | 15632 | 1249 |
Mark2,Ccl22,Mapkapk2,Lrp8,Tlr6,Ccl2,Myc,Spry2,Jun,Pik3r5,Ccl12,Cenpe,Prkar2b,Acsl1,Plscr1,Gna15,Rhoc,Ripk3,Daxx,Ahsa1,Bmp2,Nod1,Fgr,Icam1,Spata13,Pml,Ube2e1,Psme1,Dbnl,Dennd1b,Ifi205,Psmb9,Casp1,Ifi213,Tnfsf10,Pim1,Dusp5,Ifi208,Tnfsf15,Pik3r6,Gch1,Txn1,Ifi207,Irs2,Mul1,Ifi214,Tpx2,Cyth3,Nck1,Pde5a,Phactr4,Psd,Rin2,Stap1,Tor1aip2,Rapgef5,Syk,Eif2ak2,Cdkn1a,Ccl4,Jak2,Arf4,Lyn,Dennd2a,Ptk2,Mmd,Psme2,Csf1,Mndal,Adap2,Casp8,Ikbkg,Dcun1d3,S100a8,Rgs3,Rab3ip,Cd74,Asap3,Dock10,Hspa2,Sele,Errfi1,Arhgap26,Cycs,Traf2,Tnf,Irak2,Pilrb1,Il2rg,Trib3,Crkl,Tlr3,Tbc1d13,Rapgef2,Ppp1r15a,Lcp2,Ccl5,Dusp6,Plek,Angpt1,Atp2b4,Htr2a,Cdc42ep2,Nlrp3,Arrdc4,Ccnd2,Abr,Nod2,Prkce,Edn1,Dock4,Psmd10,Bcl2l11,Agrn,Map3k6,Flt1,Tagap,Rgs1,Cflar,Mefv,Adrb2,Casp7,Dcp1a,Ifi203,Casp2,Rasgrp1,Sirt1,Rabgef1,Psmb8,Mdfic,Hif1a,Malt1,Psma6,Ccnd1,Tbc1d1,Casp3,Cd40,P2ry12,Rgs14,Hsph1,Src,Tcea1,Thbs1,Elmod2,Ptafr,Fpr1,Nsmaf,Adora2a,Pdgfb,Inpp5b,Sipa1l1,Rgl1,Pilrb2,Sdc4,Cx3cl1,Nr1h3,Cdk5r1,Fas,Gadd45g,Ift57,S1pr2,Mmp14,Gclm,Trip10,Nlrc4,Gadd45b,Fam162a,Ifi204,Lpar1,Ptgir,Tlr9,Egln3,Rap1gap2,Rictor,Ifi211,Lmo4,Nos2,Cav1,Plekhg1,Ccl3,Apaf1,Pdgfc,Psmb10,F11r,Tab2,Aim2,Stat3,Ifi209,Arhgef3,Il1b,Htr2b,Pkp4,Kitl,Ralgds,Map3k8,Cdc42ep4,Adora2b,Psmb6,Ripk2,Pdgfrb,Map2k1,Fzd5,Tor1aip1,Psd4 |
| 1.197e-18 | -41.27 | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_UP | 194 | 57 | 15632 | 1249 |
Glrx,Tcea1,Acp2,Trafd1,Pkp4,Plaur,Vegfc,Plat,Il18,Kcna3,Pcgf5,Fndc3a,Cxcl2,Pdlim7,Reps1,Irf7,Rnaset2a,Tsku,Daxx,Il1a,Mthfr,Ch25h,Itga4,Ccng2,Cish,Pnp2,Egr2,Tbc1d1,Hspa1a,Ddhd1,P4ha2,Ifit2,Hsph1,Frmd6,Rnaset2b,Esd,Fam20c,Hcls1,Ldlr,Ifit3b,Acsl1,Cacnb3,St3gal5,Ampd3,Csf1,Isg20,Ptch1,Lmo4,Ifit3,Mark2,Adar,Ccl22,Col18a1,Peli1,Ccl2,Sqstm1,Eif2ak2 |
| 1.261e-18 | -41.21 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | 257 | 67 | 15632 | 1249 |
Ifi211,Isg20,Oas1a,Ifi203,Psat1,Irf8,Mndal,Cflar,Pim2,Dnajb4,Trib1,Phf11d,Ifi204,Mafg,Irf4,Myc,Ifrd1,Srm,Slc7a11,Pde3b,Phf11a,Tnfrsf14,Ifi207,Phf11c,Olr1,Atf3,Fas,Lrp8,Ccnd2,Sdc1,Ifi214,Ddit4,Slc7a5,Ifi208,Oas2,Maff,Ccr1,Dusp6,Gja1,Gdf15,Ppp1r15a,Plcl2,Zhx2,Oas1g,Hmox1,Fndc3a,Trib3,Nsmaf,Tapbpl,St7,Nr3c1,Ccnd1,Dock10,Phf11b,Ifi213,Hsph1,Casp1,Hspa1a,Ifi205,Tcf4,Ifi209,Sla,Ube2e1,Itga4,Cd180,Psmb10,St3gal6 |
| 1.265e-18 | -41.21 | negative regulation of defense response | biological process | GO:0031348 | 217 | 56 | 20694 | 1406 |
Acod1,Uaca,Cd200,Adar,Tnfaip3,Nfkb1,Tnfrsf1b,Ier3,Zc3h12a,Acp5,Fgl2,Dhx58,Nlrp3,Tap1,Lgals9,Htra1,Arg2,Mul1,Abr,Smpdl3b,Spn,Ldlr,Nmi,Samhd1,Aoah,Fpr2,Serpinb9,Rabgef1,Tap2,Calcrl,Nod2,Ptpn2,Ctla2a,Zfp36,Irak3,Il12b,Clec2d,Mefv,Nr1h3,Cst7,Socs3,Nlrc5,Ptger4,Mapkbp1,Cx3cl1,Adora2a,Slamf8,Adrb2,Trafd1,Fcgr2b,Siglece,Cx3cr1,Parp14,Ccr1,D1Ertd622e,Il10 |
| 1.314e-18 | -41.17 | regulation of peptide secretion | biological process | GO:0002791 | 528 | 95 | 20694 | 1406 |
Arid5a,Rasgrp1,Pml,Angpt1,Serp1,Il1a,Ccl3,Cx3cl1,Mapkbp1,Tnf,Rsad2,Cacna1d,Syk,Pde3b,Tlr1,Cd74,Cd14,Gsdmd,Rgcc,Hk1,Srgn,Ccl5,Rabgef1,Irs2,Slc16a1,Pfkl,Cd40,Fgr,Nlgn2,Cd34,Cd38,Hif1a,Il6,Hmga2,Cd274,Pim3,Il1b,Lgals9,Sirt1,Clcf1,Prkce,Il4ra,Osm,Klf7,Tnfrsf14,Lyn,Ifnar1,Htr2b,Gja1,Tnfsf4,Glrx,Il10,Ezr,S100a8,Tlr9,Hdac1,Adora2a,Aim2,Socs1,Rab11fip1,Mmp13,Vegfc,Ptger4,Nr1h3,Fzd5,Hcar2,Nod2,Ifih1,Sec24a,Casp1,Src,Clec5a,Gpr68,Casp4,Map4k4,Rhbdf2,Nos2,Tnfsf15,Ripk2,Arg2,Traf2,Lif,Nlrp3,Zc3h12a,Tnfrsf1b,Clec4n,Frmd4a,Hmgn3,Tlr2,Ddx58,Cd200,Clec4e,Tnfaip3,Jak2,Tlr6 |
| 1.386e-18 | -41.12 | immune system development | biological process | GO:0002520 | 748 | 119 | 20694 | 1406 |
Lyn,Relb,Nfkb1,Ahr,Pbx1,Clcf1,Acod1,Lmo4,Samd9l,Casp3,Tet2,Axl,Fubp1,Irf8,Hhex,Plcl2,Fam20c,Ifna1,Sirt1,Bcl2a1d,Cnn2,Atm,Il6,Nfkb2,Hif1a,Sema4a,Samhd1,Cd34,Spn,Tnfsf9,Plscr1,Notch2,Jmjd6,Ifnb1,Egr1,Cd74,Il12b,Bcl6,Malt1,Junb,Kitl,Jun,Sod2,Rsad2,Tnf,Syk,Cited2,Kdr,Pml,Ciapin1,Casp8,Ccr1,Ifna6,Angpt1,Ikzf1,Inhba,Tnfaip3,Sbds,Adar,Gpr18,Clec4e,Ripk3,Tlr2,Clec4d,Crkl,Tcea1,Jak2,Gfi1,Rhoh,Cd300lf,Tiparp,Pou2f2,Swap70,Heatr9,Ifna4,Batf2,Tmod3,Ifna5,Snx10,Jarid2,Ptprj,Hcls1,Rrs1,Tnfsf8,Map2k1,Dock10,H2-Ab1,Clec5a,Stat3,Bcl2l11,Csf3,Icosl,Src,Csf1,Fas,Il15,Tent2,Klf2,Stap1,Ppp4r2,Prkx,Etv6,Gadd45g,Cebpd,Pdgfrb,Fzd5,Ptpn2,Irf4,Stat5a,Pdpn,Azi2,Herc6,Ptger4,Apobec3,Ifna2,Arid4a,Slamf8,Irf1,Batf |
| 1.386e-18 | -41.12 | positive regulation of immune effector process | biological process | GO:0002699 | 253 | 61 | 20694 | 1406 |
Ptprj,Il18rap,Pvr,Adora2b,H2-M2,Ripk2,Hlx,Traf2,Ptafr,Il6,Klrk1,Raet1e,Dhx58,Il1b,Nlrp3,Zc3hav1,Il18,H2-T24,Ddx58,Hmox1,Tlr2,H2-Q4,Clcf1,Nr4a3,Lyn,Tnfrsf14,H2-T22,Il4ra,H2-T10,Nfkbiz,Rasgrp1,Arid5a,Tnfsf4,H2-Q6,H60b,Irf1,Ccl2,Fcgr1,Tlr9,Tnf,Rsad2,Cxcl1,Stat5a,Stxbp1,Syk,Il12b,Nectin2,Cd74,Ddx60,C3,Fzd5,Malt1,Rabgef1,Hk1,Tap2,H2-Q7,Nfkbid,Nod2,Ankrd17,Fgr,Cd40 |
| 1.563e-18 | -41.00 | CHEN_HOXA5_TARGETS_9HR_UP | MSigDB lists | CHEN_HOXA5_TARGETS_9HR_UP | 195 | 57 | 15632 | 1249 |
Ifi207,Egr1,Pgs1,Atf3,Ifi214,Peli1,Cnot4,Ifrd1,Nfkbia,Gadd45b,Morc3,D16Ertd472e,Ets2,Ptpn2,Tiparp,Jun,Fos,Chd9,Nfil3,Ifi204,Ifi211,Ifi203,Birc3,Gem,Mndal,Tnfaip3,Relb,Lif,Ier2,Hlx,Dusp8,Sat1,Casp3,Nfkbie,Tlk2,Ifi213,Klf6,Ifi205,Tank,Birc2,Ifi209,Sec24a,Ripk2,Dusp5,Fam53c,Spata5l1,Rcan1,Ptgs2,Ifi208,Tmeff1,Maff,Dusp6,Junb,Irf7,Fosb,Daam1,Asns |
| 1.568e-18 | -41.00 | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_UP | 189 | 56 | 15632 | 1249 |
Isg15,Rnf135,Mxd1,Prpf38a,Rnf34,P2ry12,Birc2,Plekhf2,Nfkbie,Ccng2,Stat3,1110038F14Rik,Ly75,Tnfsf8,Adora2b,Pim1,Il12b,St3gal1,Atp10a,Rnf19b,Psmb6,Smc5,Keap1,Plcl2,Slfn9,Plat,Ppp1r15a,Samsn1,Brd2,Tyk2,Phip,Enpp4,Rbl1,Sgcb,Pfkfb3,Hivep2,Eif2ak2,Adhfe1,Ccl12,Rnf114,Psd,Abcb1a,Slfn8,Aida,Mefv,Rab20,Slc25a22,Kpna3,Ell2,Pmepa1,Fscn1,Asf1a,Rgs1,Tor3a,Stat4,Trim21 |
| 1.568e-18 | -41.00 | GSE17721_CTRL_VS_LPS_6H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_6H_BMDC_DN | 189 | 56 | 15632 | 1249 |
Ccl12,Mmp14,Katna1,Kremen1,Stxbp1,Usp25,Palld,Kat2b,Cx3cl1,Hinfp,Rnd3,Ahr,Dach1,Ccne1,Cnn3,Ksr1,Plscr1,Pdss1,Slpi,Etnk1,Denr,Lyn,Ier3,Fscn1,Znrf1,Arf4,Clcf1,Vrk2,Plekhf2,Ddhd1,Timp1,Homer1,Fgl2,Acvr1,Dhx58,Psma6,F11r,Tab2,Agtrap,Cd14,Prpf38a,Pde4b,Slfn4,Cacybp,Trim26,Reps1,Hk2,Ptprj,Slc31a1,Map3k8,Il18,Ttc39b,Slfn3,Gtpbp2,Gca,Ptges |
| 1.772e-18 | -40.87 | GO_REGULATION_OF_CELL_ADHESION | MSigDB lists | GO_REGULATION_OF_CELL_ADHESION | 589 | 112 | 15632 | 1249 |
Cd86,Pik3r6,Nfkbid,Cd55,Ptprj,Ptger4,H2-Ab1,Tgfbi,Ptafr,Il12b,Il1rn,Prkx,Thbs1,Vegfc,Src,Hsph1,Swap70,Casp3,Pnp2,Acvrl1,Itga4,Hlx,Malt1,H2-Q7,Pml,Icam1,Cd83,Bmp2,Ripk3,Cd164,Notch1,Myo10,Tnfsf14,Il10,Plekha2,Rasgrp1,Tnfsf4,Ebi3,Irf1,Adrb2,Kdr,H2-Q4,Ccl12,Irf4,Il6,Peli1,Prkce,Nod2,Triobp,Prnp,Nlrp3,Il4ra,Plau,Pde3b,Tnfrsf14,Angpt1,H2-Eb1,Hsd17b12,Ccl5,Myadm,Cd274,Serpine1,Icosl,H2-Aa,Piezo1,Il12rb1,Spint2,Ripk2,Il18,Map3k8,Nr4a3,Vcam1,Gcnt2,Pkp4,Il1b,Tnf,Traf2,H2-Q6,Bcl6,Tnc,Cd74,Rnd1,Ccdc88b,Cav1,Slc9a1,Csf1,Zeb1,Rictor,Ptk2,Egr3,Itga5,Rac3,Lyn,Jak2,Spn,Itgav,Ass1,Syk,Ptpn2,Cited2,Mmp14,Ap3b1,Pde5a,Ifnb1,Nck1,Ubash3b,Cyth3,Cx3cl1,Il27,Il15,Sdc4,Cd80 |
| 1.905e-18 | -40.80 | KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 97 | 39 | 15632 | 1249 |
Cxcl10,Il12b,Tlr2,Map2k4,Pik3cd,Map3k8,Stat1,Tlr3,Tlr9,Il1b,Ccl4,Ikbke,Casp8,Irf7,Map2k1,Cd86,Nfkb1,Ikbkg,Ccl5,Tlr1,Ifna6,Akt3,Tab2,Tlr6,Ifna2,Cd14,Cd80,Myd88,Ifna1,Jun,Cd40,Fos,Ifnar1,Pik3r5,Nfkbia,Tnf,Ifna5,Ifnb1,Il6 |
| 2.056e-18 | -40.73 | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN | 190 | 56 | 15632 | 1249 |
Dusp14,Rnd3,Phip,Sdc1,Tmtc2,Cdk5r1,Nfkbiz,Mllt6,Irgm2,Il6,Cited2,Jun,Gadd45b,H2-Q4,Agrn,Nfil3,Kdr,Irf1,Ebi3,Cd200,Socs3,Ksr1,Nfkbib,Plscr1,Irf8,Tnfsf14,Notch1,Batf,Lipg,F11r,Traf1,Socs1,Pigv,H2-Q7,Mdm2,Aebp2,Dock10,Fut8,Cish,H2-Q6,Swap70,Arid5a,Insl6,Il15ra,Lacc1,Ptges,Il1rn,Spire1,Serpinb9,Usp31,Pcgf5,Hk2,Stx11,Ppp1r15a,Osm,4930523C07Rik |
| 2.330e-18 | -40.60 | hematopoietic or lymphoid organ development | biological process | GO:0048534 | 715 | 115 | 20694 | 1406 |
Sbds,Tnfaip3,Inhba,Clec4e,Gpr18,Adar,Tlr2,Clec4d,Ripk3,Tcea1,Crkl,Jak2,Gfi1,Rhoh,Tiparp,Cd300lf,Pou2f2,Heatr9,Ifna4,Batf2,Tmod3,Ifna5,Snx10,Jarid2,Hcls1,Ptprj,Dock10,Rrs1,Map2k1,Tnfsf8,Clec5a,H2-Ab1,Src,Bcl2l11,Stat3,Csf3,Csf1,Il15,Fas,Tent2,Klf2,Stap1,Ppp4r2,Etv6,Prkx,Gadd45g,Irf4,Ptpn2,Fzd5,Cebpd,Pdgfrb,Stat5a,Pdpn,Azi2,Ptger4,Herc6,Apobec3,Arid4a,Ifna2,Slamf8,Batf,Irf1,Lyn,Nfkb1,Relb,Pbx1,Ahr,Clcf1,Casp3,Lmo4,Samd9l,Axl,Tet2,Irf8,Fubp1,Hhex,Fam20c,Plcl2,Ifna1,Sirt1,Bcl2a1d,Cnn2,Atm,Il6,Nfkb2,Hif1a,Sema4a,Spn,Cd34,Tnfsf9,Plscr1,Notch2,Ifnb1,Jmjd6,Egr1,Cd74,Il12b,Bcl6,Malt1,Junb,Sod2,Jun,Kitl,Rsad2,Tnf,Cited2,Syk,Kdr,Casp8,Ccr1,Ciapin1,Pml,Ifna6,Ikzf1,Angpt1 |
| 2.383e-18 | -40.58 | negative regulation of macromolecule metabolic process | biological process | GO:0010605 | 2621 | 290 | 20694 | 1406 |
Ptgs2,Ahrr,Ifi213,Olr1,Bcl2a1d,Atm,Ddx4,Tent4a,Nfil3,Slpi,Dusp2,Fam129a,Dusp5,Cdyl,Hspa1b,Cd38,Timeless,Pik3cd,Fam72a,Hsph1,Mier3,Myadm,Ifi209,Ahr,Klf7,Lyn,Cav1,Tnip1,Ncoa7,Ptch1,Riox2,Sqstm1,Helz2,Hhex,Lgals9,Irf8,Etv3,Klf3,Sirt1,Mmp9,Plk3,Tnf,Ifi204,Daxx,Tcf4,Jun,Fzd1,Ric1,Cited2,Ago3,Caml,Parp10,Atf3,Pml,Ccr1,Angpt1,Noct,Ikzf1,Mxd1,Prdm1,Rabgef1,Serpinb9,Uchl1,Jdp2,Kat2b,Cdkn2d,Wars,Msr1,Dr1,Mtdh,Igf1r,Larp1,Rbl1,Gclc,Parp3,C3,Actb,Junb,Max,Arid5b,Aida,Gbp4,Nos2,Mvp,Serpinb6b,Parp9,Ifi208,Znfx1,Usp25,Spred1,Ptprj,Nmi,Ldlr,Smg7,Tlk2,Nfkbie,Ccne1,Ifi203,Hap1,Jarid2,Tut7,Klf8,Foxp4,Serpinb9b,Notch1,Pid1,Gfi1,Zc3h12a,Il18,Tiparp,Serpina3g,Adora2a,Tspo,Hspa1a,Ets2,Plpp3,Atp2b4,Mov10,Ptger4,Nr4a1,Ppp1r15b,Plaur,Hinfp,Tnfsf4,Dach1,Il10,Irf1,Hdac1,Phlpp1,Nsd3,Serpine1,Radx,Trim21,Edn1,Serpinb2,Xrn1,Tent2,Prkar2b,Dnaja1,Itgb8,Ctla2a,Zfp36,Svbp,Dtx3l,Irak3,Gadd45g,Dusp8,Ciita,Cflar,Sap30,Hif1a,Acvr1b,Dusp1,Il6,Kdm4a,Bmp2,Rel,Zbtb5,Nmral1,Prnp,Thbs1,Cpeb4,Lhx2,Cd34,N4bp1,Ccnd1,Tnfsf14,Keap1,Nr4a3,Psmd10,Cdk5r1,Prkce,Zmynd15,Pcx,Relb,Nfkb1,Itgav,Gja1,Casp3,Ifi205,Plat,Il1b,Isg15,Hmga2,Trib3,Polr2g,Mapkapk2,Btg2,Rfx5,Mdm2,Mdfic,Rffl,Magohb,Kdr,Dusp6,Gfpt1,Ubash3b,Arid5a,Ifi207,Cdkn1a,Phf6,Rbbp8,Mafk,Acvrl1,Myd88,Met,Nck1,Zfp281,Pmepa1,Egr1,Zhx2,Notch2,Dnajb4,Eno1,Kmt5a,Txn1,Cgas,Gadd45b,Spred3,Cst7,Ednrb,Samsn1,Ppp1r15a,Bcl6,Ifi214,Dusp4,Serpina3f,Lif,Pdgfb,Hcls1,Map2k1,Stat3,Src,Nr3c1,Adar,Tnfaip3,Trib1,Bcor,Timp1,Prdx5,Errfi1,Spint2,Cdyl2,Hat1,Crkl,Mndal,Rgs14,Swap70,Rnf139,Optn,Ifi211,Hopx,Socs1,Pnpt1,Slfn1,Eif2ak2,Aebp2,Rnf34,Plekhn1,Arid4a,Cenpj,Socs3,Mecp2,Phactr4,Ddit4,Sco1,Birc3,Mllt6,Ezr,Parp14,Ppp1r14b,Gtpbp2,Pf4,Dcp2,Spry2,Dnajb2,Zc3h7a,Dusp16,Birc2,Spen,Klf2,Etv6,Zeb1,Kdm5b,Nr1h3,Tle3,Dcp1a,Cebpd,Ptpn2,Myc |
| 2.435e-18 | -40.56 | regulation of protein secretion | biological process | GO:0050708 | 489 | 90 | 20694 | 1406 |
Tlr1,Cd14,Gsdmd,Rgcc,Hk1,Srgn,Ccl5,Rabgef1,Irs2,Slc16a1,Pfkl,Cd40,Fgr,Nlgn2,Arid5a,Rasgrp1,Pml,Serp1,Angpt1,Il1a,Ccl3,Cx3cl1,Tnf,Mapkbp1,Rsad2,Cacna1d,Pde3b,Syk,Pim3,Cd274,Il1b,Lgals9,Sirt1,Prkce,Il4ra,Osm,Klf7,Tnfrsf14,Lyn,Ifnar1,Htr2b,Gja1,Cd34,Cd38,Hif1a,Il6,Nr1h3,Fzd5,Hcar2,Nod2,Ifih1,Tnfsf4,Glrx,Il10,Ezr,Tlr9,Hdac1,Adora2a,Aim2,Socs1,Rab11fip1,Mmp13,Ptger4,Vegfc,Nlrp3,Zc3h12a,Tnfrsf1b,Clec4n,Frmd4a,Hmgn3,Tlr2,Ddx58,Clec4e,Cd200,Tnfaip3,Jak2,Tlr6,Sec24a,Casp1,Src,Clec5a,Gpr68,Casp4,Map4k4,Rhbdf2,Nos2,Tnfsf15,Ripk2,Arg2,Traf2 |
| 2.484e-18 | -40.54 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_DN | 150 | 49 | 15632 | 1249 |
Ppm1k,Irf7,Pde4b,Ccl5,Oas2,Tnfsf15,Usp42,Ptgs2,Kdm6b,Atp10a,Herc6,Epsti1,Il15ra,Gtpbp2,Snapc1,Tnfsf10,Traf2,Tnf,Sp140,Dhx58,Ddx58,Stat2,Trim12c,Gbp3,Ifih1,Dtx3l,Mxd1,Aim2,Csrnp1,Cd38,Irf8,Abtb2,Rictor,Dcp1a,Irf1,Fam111a,Dgkh,Znfx1,D16Ertd472e,Parp14,Peli1,Etv3,Ddx60,Fas,Tap1,Zc3hav1,Il15,Zbtb5,Adar |
| 2.485e-18 | -40.54 | ONDER_CDH1_TARGETS_2_DN | MSigDB lists | ONDER_CDH1_TARGETS_2_DN | 429 | 91 | 15632 | 1249 |
Cdk5r1,Sdc1,Ddx60,Sdc4,B4galt4,Syk,Rapgef5,Pla2g4a,Ctsc,Lyn,C3,Mmp9,Cd82,Sema3c,S100a8,Slpi,Pstpip2,Isg20,Arg2,Ifih1,Upp1,F11r,Prrg4,Tnfaip3,Oas3,Rhbdf2,Arhgef3,Homer1,Mtus1,Ccng2,Il18,Ptges,Il1b,Cxcl1,Pcdh7,Fzd5,Dusp6,Cxcl2,Spint2,Parp12,Inhba,Il4ra,Ccnd2,Atp2b4,Gclc,Plau,Fos,Flrt3,Agrn,Peli1,Pdpn,Edn1,Tlr2,Adrb2,Ier3,Rims3,Lcn2,P2ry2,Gna15,Birc3,Smpdl3b,Ampd3,Flnb,Ddx58,Icam1,Il1a,Bmp2,Cd83,Casp1,Ly75,Ptafr,Mob3b,Ptgs2,Zc3h12a,Herc6,Cd55,Zhx2,Il15ra,Serpinb2,Tnfsf10,Il1rn,Myo1b,Plk2,Lad1,Gch1,4930523C07Rik,Slc31a2,Snx10,Slc7a8,Csf3,Slc7a5 |
| 2.645e-18 | -40.47 | GSE22432_CONVENTIONAL_CDC_VS_PLASMACYTOID_PDC_DN | MSigDB lists | GSE22432_CONVENTIONAL_CDC_VS_PLASMACYTOID_PDC_DN | 179 | 54 | 15632 | 1249 |
Setdb2,Tlk2,Glipr2,Tapbp,Stk40,Parp8,Lrp4,Casp1,Cst7,Traf2,1600014C10Rik,Stat2,Cd180,Gbp3,Rab10,Nmi,Il12rb1,Stoml1,Asah2,Tap2,Cnp,Sipa1l1,Gtpbp2,Cldnd1,Il15ra,Trafd1,Htr2b,Glrx,Herc6,Xkr8,Slamf8,Il12b,Parp14,Rnf114,Clec4e,Rbm43,Tap1,Pgs1,Ddx60,Stxbp1,Ccnd2,Pttg1,Mpp7,Tdrd7,Tor3a,Psmb8,Rnf31,Mov10,Nos2,Ap3m2,Vrk2,Cdkn1a,Endod1,Il13ra1 |
| 2.645e-18 | -40.47 | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN | 179 | 54 | 15632 | 1249 |
Tspo,Pfkfb3,Samhd1,Tap1,Stxbp1,Abr,Irgm2,Il18bp,Sod2,Ccl12,Hcls1,Tnfaip2,Ppa1,C3,Irf1,Psme2,Flnb,Trim21,Cnn3,Isg20,Zeb1,Gbp7,Ogfr,Hdc,Irf8,Gbp2,Notch1,Daxx,Pml,Psme1,Psmb10,Slco3a1,Socs1,Upp1,Cd180,Stat3,1110038F14Rik,Glipr2,Plod3,Tpst1,Cmpk2,Traf3ip2,Rnf19b,Grina,Pim1,Noc4l,Inpp5b,Ube2l6,Uba7,Wars,Il12rb1,Bst1,Nampt,Tap2 |
| 2.645e-18 | -40.47 | GSE17721_CTRL_VS_POLYIC_24H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_24H_BMDC_DN | 179 | 54 | 15632 | 1249 |
Rgl1,Gch1,Gdf15,Ccl5,Slfn4,Ppp1r15a,Sap30,Inhba,G3bp2,Hk2,Ripk2,Slamf8,Slfn3,Slc29a3,Ptges,Keap1,Htr2b,Tnf,N4bp1,Ttc39c,Timp1,Mecp2,Fgl2,Pml,Nupr1,Tab2,Bfar,Cd83,Mdfic,Pdk3,Cav1,Cep350,Lmo4,Lap3,Zeb1,Spen,Fabp7,Mtmr14,Ddx4,Arf4,Jak2,Cd82,Lhx2,Esd,Nfkbia,Ift57,Abr,Usp25,Stxbp1,Cx3cl1,Prdx1,Gclc,Gng11,Slc28a2 |
| 2.689e-18 | -40.46 | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | MSigDB lists | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | 191 | 56 | 15632 | 1249 |
Zc3h12a,Scyl2,Il12b,Ptafr,Il2rg,Slc43a3,Slamf8,Nfkb2,Clic4,Bcl2a1a,Il1rn,Il1b,Plaur,Map4k4,Txn1,Serpine1,Cxcl2,Maff,Inhba,Marcksl1,Fgr,Il1a,Upp1,Kmo,Relb,Crim1,Slc16a3,Src,Eno1,Ccdc86,Cycs,Minpp1,Gpr68,Gsr,Bcl2a1d,Ebi3,Tnip3,Ccl4,Tnip1,Fscn1,Pmepa1,Alas1,Pdss1,Fpr2,Ccl22,Cd80,Sdc4,Olr1,Bcl2a1b,Jun,Hmga1,Igsf6,Il6,Ccl2,Pdpn,Chst11 |
| 2.836e-18 | -40.40 | regulation of cellular macromolecule biosynthetic process | biological process | GO:2000112 | 3242 | 341 | 20694 | 1406 |
Myc,Fzd5,Ptpn2,Dcp1a,Cebpd,Plagl2,Pdgfrb,Kdm5b,Zeb1,Fosb,Etv6,Tle3,Nr1h3,Spen,Klf2,Ifrd1,Csrnp1,Rhoq,Aff1,Nupr1,Il15,Med21,Slc9a1,Dcp2,Gtpbp2,Adrb2,Pf4,Tlr9,Nfkbia,Spic,Batf,Maml2,Ezr,Mllt6,Mecp2,Plekhn1,Arid4a,Aebp2,Stat5a,Ell2,Hopx,Eif2ak2,Slfn1,Plagl1,Ifi211,Sp140,Plac8,Pou2f2,Rnf139,Rgs14,Mndal,Nlrp3,Sphk1,Hat1,Tcea1,Prdx5,Jak2,Tlr6,Bcor,Stat1,Nlrc4,Irf7,Trib1,Tnfaip3,Inhba,Cd200,Ddx58,Maff,Hmgn3,Traf5,Ripk3,Nr3c1,Egr3,Peli1,Src,Hck,Stat3,Tfec,Stat2,Eif4g2,Hcls1,Map2k1,Pdgfb,Lif,Mafg,Ptafr,Batf2,Wdr43,Psma6,Bcl6,Ifi214,Gdf15,Ppp1r15a,Ednrb,Txn1,Kdm6b,Agrn,Kmt5a,Dnajb4,Eno1,Brd2,Zhx2,Notch2,Egr1,Rgcc,Zfp281,Nck1,Acvrl1,Mafk,Met,Myd88,Serp1,Phf6,Cdkn1a,Ifi207,Nampt,Zfp513,Etv5,Arid5a,Fcgr2b,Nlrc5,Cacybp,Egr2,Kdr,Gfpt1,Cacna1d,Cx3cl1,Mdfic,Rfx5,Mdm2,Btg2,Pttg1,Trib3,Fubp1,Polr2g,Tet2,Il1b,Tal2,Hmga2,Ifi205,Tlr3,Gja1,Ikbkg,Ifnar1,Crlf3,Zmynd15,Nfkb1,Relb,Ccnd1,Cdk5r1,Psmd10,Keap1,Nr4a3,Cpeb4,Lhx2,Thbs1,Prdm9,Prnp,Nmral1,Fbxo4,Rel,Zbtb5,Bmp2,Il6,Nfkb2,Kdm4a,Perm1,Dusp1,Acvr1b,Hif1a,Ciita,Cflar,Sap30,Tnfrsf8,Mamld1,Jag1,Dtx3l,Irak3,Irf4,Zfp36,Sav1,Med13,Hivep3,Edn1,Trim21,Xrn1,Resf1,Nfkbid,Hmga1,Nod2,Lrp8,Nsd3,Hdac1,Klhl25,Irf1,Dach1,Cx3cr1,Il10,Irf2,Acvr1,Hinfp,Nr4a1,Ppp1r15b,Tnfsf4,Map2k4,Plpp3,Mov10,Atp2b4,Ets2,Cmklr1,Aim2,Adora2a,Irak2,Ythdf1,Zc3h12a,Il18,Pid1,Gfi1,Notch1,Nfkbib,Foxp4,Klf8,Pim1,Hmox1,Tlr2,Trim26,Nfkbil1,Dyrk2,Csf3,Hivep2,Ifi203,Ccne1,Jarid2,Smg7,Nfkbie,Tnfsf8,Il18rap,Traf2,Htra1,Ripk2,Ifi208,Parp9,Hlx,Znfx1,Gbp4,Rnf14,Max,Rnf31,Arid5b,Malt1,Junb,Parp3,Pou3f1,Cd74,Gclc,Mycl,Ankrd17,Mtdh,Psip1,Cd40,Rbl1,Larp1,Igf1r,Tshz1,Igf2bp2,Phip,Dr1,Nod1,Ifnb1,Kat2b,Irs2,Jdp2,Jmjd6,Trim14,Icam1,Mxd1,Prdm1,Ikzf1,Atf3,Pml,Brwd3,Ago3,Parp10,Sertad3,Taf4b,Pim2,Stat4,Syk,Cited2,Bambi,Pcgf5,Tcf4,Jun,Sod2,Fzd1,Tnf,Plk3,Il1a,Daxx,Ifi204,Ccl3,Arf4,Etv3,Klf3,Sirt1,Trim13,Irf8,Hhex,Sqstm1,Helz2,Ptch1,Acod1,Lmo4,Cav1,Klf7,Osm,Tnip1,Ncoa7,Pbx1,Ifi209,Ahr,Hsph1,Tax1bp1,Timeless,Cd38,Mier3,Plscr1,Dusp5,Fam129a,Nfxl1,Nfil3,Cyfip1,Atm,Klf6,Casz1,Bcl9,Ier2,Traf1,Fos,Ahrr,Ifi213 |
| 2.891e-18 | -40.39 | positive regulation of cell-cell adhesion | biological process | GO:0022409 | 242 | 59 | 20694 | 1406 |
Nck1,Adam19,Ccl2,Irf1,Ikzf1,Rasgrp1,Tnfsf4,Plpp3,H2-Aa,Cited2,Syk,Stat5a,Pdpn,Cx3cl1,Tnf,Ap3b1,Socs1,Bcl6,Myo10,Itga4,Malt1,Ccdc88b,Cd74,Il12b,Vcam1,Nfkbid,Ccl5,Icam1,Il15,Hsph1,Spn,H2-Ab1,Egr3,Tnfsf9,Gcnt2,Icosl,Cd86,Il6,Cd80,Ptafr,Ripk2,Hlx,Il2rg,Piezo1,Itgal,Il18,Lgals9,Pik3r6,Il1b,Cd83,Cd274,Nlrp3,Nfkbiz,Cav1,Tnfrsf14,Il12rb1,Il4ra,Tnfsf14,Nr4a3 |
| 3.178e-18 | -40.29 | regulation of biological quality | biological process | GO:0065008 | 4046 | 405 | 20694 | 1406 |
Hdac1,Plau,Cdc42ep4,Tnfsf4,Xkr8,Hdc,Abcb1a,Atp2b4,Mov10,Ptger4,Mmp13,Ehd1,Adora2a,Slc12a9,Gadd45g,Zfp36,Morc3,Dhrs9,Enpp4,Tent2,Trim21,Xrn1,Homer1,Serpine1,Carmil1,Tmsb10,Nod2,Flrt2,Lrp8,Map4k4,Gcnt2,Csf3,Cdc42ep2,Xcr1,Ptprj,Stx11,Ass1,Scn1b,Atp10a,1600014C10Rik,Irgm2,Sesn3,Smc5,Nos2,Tiparp,Pid1,Rhoh,Notch1,Rnd3,Pim1,Hmox1,Tlr2,Rab20,Noct,Brwd3,Pml,Ccr1,Pim2,Syk,Pde3b,Ccl4,Sod2,Fzd1,Ccl3,Pde4b,Oas2,Fpr1,Fabp3,C3,Cd74,Fgr,Larp1,Igf1r,Cutc,Phip,Nox1,Msr1,Ccl5,Cxcl2,Cd38,Slc39a13,Whamm,Adgrl2,Tent4a,Atm,Acsl1,Rmdn3,Abr,Arf4,Ier3,Grina,Txnrd1,Axl,Gpsm2,Usp18,Slc39a4,Ptch1,Htr2b,Rims3,Pdzd11,Atp11a,Lyn,Slc7a11,Il4ra,Ahr,Clcf1,Slc9a1,Pf4,Tlr9,Ppfia3,Dio2,Ezr,Glrx,Mecp2,Vegfc,Cxcl1,Rhou,Ap3b1,Vps54,Myc,Myo10,Pde5a,Htr2a,Fcgr4,Kmo,Pde1b,Klf2,Ntng2,Ccrl2,Dock4,Sema3c,Gpr68,Hck,Stat3,Src,Lcn2,Kcnj2,Lst1,Sec24a,Ampd3,Hcls1,Tapbp,4932438A13Rik,Ero1l,Pdgfb,Klrk1,Mafg,Cxcl10,Ptafr,Lpar1,Ikbke,Piezo1,Swap70,Hk3,Apba1,Crkl,Stat1,Flrt3,Prdx5,Ncoa5,Cxcl3,Adar,Ripk3,Serp1,Myd88,Met,Gch1,Fcgr2b,Col11a2,Ubash3b,Kdr,Kitl,Cacna1d,Cx3cl1,Plod3,Bcl6,Slc4a7,Ppp1r15a,Mark2,Rnd1,Txn1,Il1rn,Kdm6b,Vcam1,Egr1,Mt1,Thbs1,Plk2,Cd34,Cacnb3,Prnp,Fbxo4,Sema4a,Il6,Hif1a,Vasp,Atp11b,Mdm2,Slc7a2,Pdgfc,Procr,Mapkapk2,Tmtc2,Hmga2,Hk2,Gja1,Itgav,Casp3,Rhof,Ikbkg,Ccnd1,Nr4a3,Psmd10,Fmnl2,Gk,Cx3cr1,Il10,Rab21,Cnp,Plpp3,Hspa1a,Cmklr1,Lnpk,Rab11fip1,Tspo,Fchsd2,Gclm,Lnpep,Irf4,Rhoc,Sav1,Ccr3,Ptgir,Med13,Stau1,Edn1,Sema4c,Papss2,Fas,Ccne1,Hap1,Casp1,Ldlr,Smg7,Usp25,Tmem178,Lrp4,Mul1,Tmod3,Zc3h12a,Il18,Gfi1,Chmp4b,Nfkbib,Marcksl1,Slc31a1,Usp53,Gpr18,Prdx1,Angpt1,Ikzf1,Caml,Tmem123,Ccl12,Cited2,Stxbp1,Bambi,Jun,Tnf,Il1a,Lipg,Parp3,Gclc,Nlgn2,Atp13a1,Cd40,Pfkl,Dync1h1,Slc16a1,Jmjd6,Irs2,Kat2b,Icam1,Hk1,Pik3cd,Rapgef2,Dmxl2,Dusp5,Plscr1,F10,Adora2b,Cyfip1,Hilpda,Syne2,Ptgs2,Gna15,Plcl2,Sirt1,Mmp9,Lgals9,Sqstm1,Dbnl,Itpr1,F11r,Klf7,Cav1,Osm,Myadm,Spire1,Slc31a2,Slamf8,Nfkbia,Adrb2,Slc30a1,Dcp2,Evl,Ccl2,Mllt6,Sco1,Plekhn1,Arid4a,Stat5a,Pdpn,Pdgfrb,Ptpn2,Ptk2,Prag1,Kdm5b,Rac3,Nr1h3,Tle3,S1pr2,Ifrd1,Sipa1l1,Rhoq,Igsf9,Csf1,Gsr,Il15,Hcar2,Nr3c1,Bcl2l11,Bcl2a1a,Fpr2,Snx10,Pdk3,Eif4g2,Map2k1,Dock10,Lif,Plac8,Tnfrsf1b,Rnf139,Akt3,Rgs14,Rap1gap2,Sphk1,Tcea1,Tlr6,Jak2,Inhba,Tnfaip3,Rictor,Hmgn3,Nck1,Acvrl1,Gpr35,Agtrap,Nampt,Pla2g4a,Etv5,Cp,Abcc1,P2ry12,Mt2,P2ry2,Bnip3,Carhsp1,Ednrb,Tha1,Agrn,Slc28a2,Mosmo,Clic4,Stxbp3,Srgn,Nrp2,Plek,Bmp2,Acvr1b,Phgdh,Lox,Ttc39b,Acp5,Tet2,Pmaip1,Il1b,Isg15,Pim3,Slc39a14,Slc30a4,Nfkb1,Keap1,Prkce,Cdk5r1 |
| 3.249e-18 | -40.27 | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP | MSigDB lists | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP | 168 | 52 | 15632 | 1249 |
Agtrap,Il1a,F11r,Csrnp1,Plk3,Ch25h,Homer1,Dusp1,Cebpd,Egr2,Nr4a3,Rcan1,Ptgs2,Dusp5,Kdm6b,Rnf19b,Plaur,Thbs1,Bambi,Cxcl1,Cmklr1,Serpine1,Fosb,Plk2,Ppp1r15a,Dusp6,Junb,Maff,Arl5b,Btg2,St3gal3,Egr1,Atf3,Rnd3,Slc25a25,Sdc4,Jun,Ets2,Fos,Ccl12,Agrn,Adhfe1,Nr4a1,Myc,Edn1,Spry2,Ier3,Casp7,Gem,Jdp2,Ccrl2,Zfp36 |
| 3.252e-18 | -40.27 | regulation of leukocyte cell-cell adhesion | biological process | GO:1903037 | 287 | 65 | 20694 | 1406 |
Ccdc88b,Cd74,Il12b,Bcl6,Pde5a,Itga4,Ptpn2,Malt1,Ifnb1,Nfkbid,Ccl5,Il15,Icam1,Vcam1,Rasgrp1,Sdc4,Tnfsf4,Nck1,Ikzf1,Ccl2,Irf1,Stat5a,Ap3b1,Tnf,Socs1,Adora2a,Slfn1,Syk,H2-Aa,Lgals9,Pik3r6,Il1b,Nlrp3,Cd274,Cd83,Zc3h12a,Itgal,Fgl2,Il18,Cav1,Tnfrsf14,Tarm1,Il12rb1,Il4ra,Tnfsf14,Nr4a3,Nfkbiz,Casp3,Cd86,Ass1,Hsph1,Spn,Tnfsf9,Prnp,H2-Ab1,Egr3,Peli1,Icosl,Hlx,Ripk2,Il2rg,Il6,Cd80,Ptafr,Arg2 |
| 3.400e-18 | -40.22 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_UP | 174 | 53 | 15632 | 1249 |
Tnfaip3,Cd83,Gys1,Traf1,Hlx,Aim2,Rsad2,Bcl2a1d,Psma6,Sat1,Itgb8,Ly75,Dusp1,Zhx2,Bcl2a1a,Nfkb2,Ak4,Nr4a3,St3gal1,Dusp5,Rapgef2,Ddit4,Nrp2,Tap2,Pde4b,Txn1,Gch1,Tap1,Rnd3,Arl4a,Gbe1,Dusp4,Bnip3,Trip10,Rab32,Nfkbia,Bcl2a1b,Sod2,Gfi1,Cacna1d,Cflar,Tnip1,Rgs1,Ifit3b,Ifi35,Cd200,Etv6,Isg20,Cnn3,Bcl9,Psme2,Ifit3,Nfkb1 |
| 3.400e-18 | -40.22 | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_DN | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_DN | 174 | 53 | 15632 | 1249 |
Slc25a25,Sdc4,Nfkbiz,Atf3,Il6,Myc,Edn1,Spry2,Ccl12,Nr4a1,Jun,Fos,Nfil3,Cd300e,H3f3b,Casp7,Sema4c,Ier3,Zfp36,Ccrl2,Jdp2,Il10,Cd14,Tnfaip3,Myo10,Ier2,Ch25h,Plk3,F11r,Il1a,Cp,Hspa2,Cebpd,Lrp4,Ehd1,Dusp1,Cmklr1,Plaur,Dusp5,Kdm6b,Ptger4,Rnf19b,Nr4a3,Ptgs2,Rcan1,Btg2,Maff,Mmp13,Dusp6,Junb,Fosb,Serpine1,Plk2 |
| 3.493e-18 | -40.20 | GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY7_UP | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY7_UP | 180 | 54 | 15632 | 1249 |
Trafd1,Cmpk2,Keap1,Snn,Oas1g,St3gal1,Herc6,Naa25,Smox,Frmd4a,Tyk2,Irf7,Fzd5,Cnp,Tor1aip1,1600014C10Rik,Relb,Pml,Ifih1,Ddx58,Setdb2,Casp3,Dhx58,Tapbp,Treml2,Dync1h1,Oas3,Jak2,Zcchc2,Ap3m2,Dck,Ifit3b,Slc25a22,Trib1,Mppe1,Psme2,Trim14,Xaf1,Slamf9,Oas1a,Ubr4,Ifit3,Rbm43,Sgcb,Mark2,Slc30a1,Pttg1,Prkce,Ikzf1,Parp9,Samd9l,Pik3r5,Rnf114,Tmem184b |
| 3.497e-18 | -40.19 | GO_REGULATION_OF_CELL_CELL_ADHESION | MSigDB lists | GO_REGULATION_OF_CELL_CELL_ADHESION | 358 | 81 | 15632 | 1249 |
Cd74,Hlx,Itga4,Malt1,H2-Q7,Ripk3,Myo10,Cd83,Ccdc88b,Bmp2,Traf2,H2-Q6,Swap70,Bcl6,Src,Tnf,Hsph1,Casp3,Pnp2,Map3k8,Ptafr,Il18,Il12b,Nr4a3,Cd55,H2-Ab1,Ripk2,Il1b,Il1rn,Vcam1,Gcnt2,Cd86,Cd274,Pik3r6,H2-Eb1,Ccl5,Myadm,Il12rb1,Nfkbid,Spint2,Icosl,Piezo1,H2-Aa,Ubash3b,Prnp,Nlrp3,Il4ra,Cx3cl1,Nck1,Tnfrsf14,Il27,Il15,Cd80,Cited2,Ptpn2,H2-Q4,Spn,Ass1,Syk,Ccl12,Nod2,Ap3b1,Pde5a,Ifnb1,Irf4,Il6,Peli1,Irf1,Lyn,Adrb2,Ebi3,Tnfsf4,Egr3,Ptk2,Jak2,Tnfsf14,Cav1,Il10,Rictor,Rasgrp1,Zeb1 |
| 3.515e-18 | -40.19 | TIAN_TNF_SIGNALING_VIA_NFKB | MSigDB lists | TIAN_TNF_SIGNALING_VIA_NFKB | 25 | 20 | 15632 | 1249 |
Tnfaip3,Relb,Cd83,Cxcl1,Sdc4,Tnfaip2,Tnip1,Nfkb2,Ptgs2,Irf1,Traf1,Nfkbie,Cxcl2,Zfp36,Il6,Rel,Plk2,Nfkbia,Gch1,Nfkb1 |
| 4.197e-18 | -40.01 | positive regulation of leukocyte differentiation | biological process | GO:1902107 | 168 | 48 | 20694 | 1406 |
Syk,H2-Aa,Stat5a,Jun,Kitl,Ccl3,Socs1,Ap3b1,Tnf,Prdm1,Pf4,Ikzf1,Irf1,Casp8,Ccr1,Tnfsf4,Rasgrp1,Nfkbid,Notch2,Il15,Csf1,Ccl5,Bcl6,Malt1,Cd74,Mmp14,Il12b,Lif,Il6,Fos,Il2rg,Ripk2,Hlx,Gpr68,Tnfsf9,Egr3,Hcls1,Nfkbiz,Il4ra,Trib1,Il18,Axl,Il15ra,Lgals9,Nlrp3,Cd83,Pik3r6,Il1b |
| 4.216e-18 | -40.01 | regulation of leukocyte differentiation | biological process | GO:1902105 | 296 | 66 | 20694 | 1406 |
Tnf,Ap3b1,Socs1,Ccl3,Jun,Kitl,Stat5a,Ubash3b,Syk,H2-Aa,Rasgrp1,Tnfsf4,Ccr1,Casp8,Ikzf1,Irf1,Slamf8,Il27,Tmem176a,Prdm1,Pilrb1,Pf4,Tlr9,Csf1,Ccl5,Il15,Fas,Notch2,Tmem176b,Ifnb1,Nfkbid,Zeb1,Il12b,Clec2d,Cd74,Mmp14,Malt1,Ptpn2,Ctla2a,Bcl6,Myc,Ripk2,Hlx,Il2rg,Fos,Il6,Tmem178,Lif,Hcls1,Tnfsf9,Egr3,Gpr68,Trib1,Lyn,Il4ra,Nfkbiz,Pik3r6,Il1b,Nlrp3,Cd83,Il15ra,Lgals9,Axl,Zc3h12a,Il18,Fgl2 |
| 4.354e-18 | -39.98 | MISSIAGLIA_REGULATED_BY_METHYLATION_UP | MSigDB lists | MISSIAGLIA_REGULATED_BY_METHYLATION_UP | 114 | 42 | 15632 | 1249 |
Dusp5,Stat1,Oas1g,Cd55,Ptgs2,Rcan1,Plat,Tnfaip2,Arf4,Cdkn1a,Il1b,Dnajb2,Sp110,Plaur,Dusp6,Ifit1bl2,Birc3,Serpine1,Lcn2,Slpi,St3gal5,Ube2l6,Isg20,Trim21,Oas2,Oas1a,Atf3,Rnd1,Isg15,Sdc4,Tnfaip3,Tap1,Sqstm1,Sod2,P4ha2,Dusp1,Ifit1bl1,Tmem184b,Timp1,Rab9,Sat1,Prdx5 |
| 4.570e-18 | -39.93 | GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDC_DN | 193 | 56 | 15632 | 1249 |
Trem1,Ldlr,Tnip1,Trib1,Tlr2,Jag1,Rnf19a,Met,Rasgrp1,Zfp36,Birc3,Tnfrsf1b,Klf7,Pim3,Rnd3,Slc25a25,Etv3,Sdc1,Nlrp3,Pla2g4a,Fcgr2b,Ccl2,Mmp14,Tiparp,Ets2,Sbds,Syk,Ccl12,Hcar2,Slfn3,Plat,Chic2,Pim1,Kcna3,Fpr1,Clec4d,St3gal1,Rnf19b,Ripk2,Adora2a,Pdgfb,Icosl,Cd274,Lcp2,Slfn4,Rrs1,Fosb,Med21,Pde4b,Brd2,Icam1,Spata13,Marcksl1,Mcoln2,Errfi1,Cish |
| 4.602e-18 | -39.92 | GSE17721_CTRL_VS_CPG_12H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_12H_BMDC_DN | 181 | 54 | 15632 | 1249 |
Hdac1,Fgl2,Lztfl1,Gypc,Cst7,Myd88,Rab3ip,Mcmbp,Plagl2,Tab2,Socs1,Jmjd6,Rab10,Reps1,Rgl1,Ccl5,Gch1,Ppp1r15a,Pkp4,Glrx,Atp10a,Hmox1,Slc31a1,Ripk2,Slamf8,Pim1,Grina,Serpinb9,Il18,Parp14,Rai14,Psd,Vcan,Cpd,Rab32,Sod2,Sqstm1,D16Ertd472e,Hinfp,Olr1,Atf3,Stxbp1,Palld,Flnb,Timeless,Eef1e1,Lmo4,Gfpt1,Clcf1,Mtdh,Ebi3,Rcsd1,Ddx4,Lyn |
| 4.621e-18 | -39.92 | HALLMARK_COMPLEMENT | MSigDB lists | HALLMARK_COMPLEMENT | 187 | 55 | 15632 | 1249 |
Psmb9,Timp1,Src,Ehd1,Casp1,Dock10,C1ra,Casp3,Cp,Irf2,Tnfaip3,Gnb4,Lcp2,Irf7,Serpine1,Plek,Dusp6,Csrp1,Ccl5,Mmp13,Maff,Pdgfb,Pim1,Cd55,Dusp5,Plaur,Gca,Plat,Serpinb2,Dock4,Pik3r5,Pla2g4a,Ctsc,Mmp14,Il6,Cdk5r1,Me1,Olr1,Vcpip1,F10,Col4a2,Casp4,Lap3,Pla2g7,Rasgrp1,Zeb1,Plscr1,Irf1,Gpd2,Lyn,Dgkh,Casp7,C3,Dyrk2,Jak2 |
| 4.637e-18 | -39.91 | BROWN_MYELOID_CELL_DEVELOPMENT_UP | MSigDB lists | BROWN_MYELOID_CELL_DEVELOPMENT_UP | 152 | 49 | 15632 | 1249 |
Ccr1,Slc31a2,Junb,Slfn4,Myo1b,Slfn3,Il1rn,Bcl2a1a,Il1b,Glrx,Plaur,Fpr1,Tgfbi,Clec5a,Grina,Slc15a3,Sat1,Bcl2a1d,Cebpd,Glipr2,Tnf,Arhgef3,Hck,Hlx,Mxd1,Plk3,Fgr,Upp1,Pstpip2,Clec4n,Lcn2,C3,Tlr2,Il4i1,Nqo1,Cpd,Samd9l,Bcl2a1b,Cnn2,Aoah,Zyx,Fcgr1,Cd80,F10,Olr1,Egr1,Sgms2,Fpr2,Ccnd2 |
| 4.921e-18 | -39.85 | Cytokine Signaling in Immune system | REACTOME pathways | R-MMU-1280215 | 510 | 106 | 8608 | 757 |
Tnfsf4,Ube2e1,Tnfsf15,Ptk2,Cd40,Psme1,Psmb6,Ifnb1,Flnb,Ifna4,Stat1,Irak3,Nod1,Irak2,Usp18,Tab2,Ppp2r5a,Socs3,Tnfrsf1b,Jak2,Map2k1,Tnfsf14,Map3k8,Psmd10,Psmb10,Il27,Clcf1,Tnfsf8,Cish,Tnfrsf14,Il13ra1,Il15ra,Il18rap,Pik3cd,Ifna6,Stat5a,Tnf,Nfkb2,Lgals9,Psme2b,Birc2,Casp1,Ifna5,Lyn,Nod2,Il15,Eif4g2,Ppp2r1b,Lif,Socs1,Il18bp,Peli1,Traf2,Psme2,Csf3,Psma6,Met,Stat3,Birc3,Osm,Ptpn2,Ripk2,Psmb8,Ube2l6,Dusp5,Dusp6,Rapgef2,Ebi3,Rasgrp1,Tnfsf9,Irs2,Il1rn,Kitl,Pdgfb,Ifnar1,Ksr1,Ifna1,Il2rg,Ifna2,Pdgfrb,Il1a,Il10,Relb,Tyk2,Casp3,Myd88,Csf3r,Ikbkg,Crkl,Il4ra,Il12b,Sqstm1,Psmb9,Angpt1,Uba7,Il6,Src,Il18,Spred1,Nfkb1,Il12rb1,Tnfrsf8,Stat2,Syk,Il1b,Isg15 |
| 5.346e-18 | -39.77 | HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN | MSigDB lists | HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN | 76 | 34 | 15632 | 1249 |
Slfn4,Lcn2,Plek,Myadm,Btg2,Zfp36,Plscr1,Phlda1,Tgfbi,Tlr2,Il18,Fpr1,Mmp9,Il1b,Cxcl1,Slfn3,Pilrb1,Cd300lf,Gcnt2,Fos,Msr1,Dusp1,Ehd1,Vcan,Egr2,Upp1,Fgr,Arg2,P2ry14,Egr1,Hck,Samhd1,Pilrb2,Fcgr1 |
| 5.387e-18 | -39.76 | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | MSigDB lists | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | 325 | 76 | 15632 | 1249 |
Olr1,Ifi207,Col4a2,Sgcb,Plau,P2ry14,Ifi214,Prnp,Ccnd2,Palld,Fas,Sdc2,Vcan,Kcnj2,Msr1,Pmepa1,Kdr,Hcls1,Rgs1,Adam19,Lyn,Ms4a6d,Ifi204,Tnfsf4,Kctd12,Ifi203,Htra1,Akt3,Ifi211,Zeb1,Mndal,Gem,Irf8,Irak3,Olfml3,Etv5,Sphk1,St3gal6,Cd74,Ch25h,C1ra,Fgl2,Ifi209,Tcf4,Ifi205,Dse,Psmb9,Slc16a3,Casp1,Dpy19l1,Axl,Ifi213,Glrx,Htr2b,Abcc4,Tfec,Plaur,Il18,Lox,Tgfbi,Slamf8,Hmox1,Cd55,H2-Ab1,Inhba,Mmp13,Ifi208,H2-Aa,Tmeff1,Pdgfrb,Samsn1,Lcp2,Ccl5,Map4k4,Fcgr4,Ccr1 |
| 5.431e-18 | -39.75 | positive regulation of DNA-binding transcription factor activity | biological process | GO:0051091 | 245 | 59 | 20694 | 1406 |
Fzd1,Cacna1d,Eif2ak2,Tnf,Aim2,Cx3cl1,Plpp3,Il10,Cx3cr1,Fcgr2b,Tlr9,Myd88,Nod1,Nod2,Rgcc,Icam1,Lrp8,Trim14,Cd40,Ifrd1,Mtdh,Edn1,Trim21,Sav1,Arid5b,Irak3,Rnf31,Malt1,Traf1,Cflar,Ripk2,Tnfrsf8,Psma6,Il6,Traf2,Il18rap,Hcls1,Trim26,Csf3,Stat3,Cav1,Tlr2,Ripk3,Traf5,Hmgn3,Cd200,Ddx58,Tlr3,Sphk1,Nlrc4,Ikbkg,Jak2,Tlr6,Trim13,Nlrp3,Hmga2,Il1b,Irak2,Il18 |
| 5.498e-18 | -39.74 | GO_NEGATIVE_REGULATION_OF_CELL_DEATH | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 797 | 136 | 15632 | 1249 |
Icam1,Hif1a,Il1a,Sphk1,Malt1,Notch1,Hck,Bfar,Timp1,Hspa1a,Birc2,Dusp1,Axl,Hsph1,Src,Insl6,Acvr1,Mdm2,Stk40,Bcl2a1d,Casp3,Rffl,Clec5a,Grina,Pim1,Serpinb9,Zc3h12a,Plaur,Pf4,Bcl2a1a,Thbs1,Tnfsf10,Serpinb2,Plk2,Txn1,Map4k4,Csf3,Btg2,Phip,Prnp,Chmp4b,Angpt1,Gclc,Adar,Psmd10,Jun,Nfkbia,Cx3cr1,Ccl12,Chst11,Nod2,Edn1,Spry2,Prokr1,Myc,Il6,Ier3,Socs3,Igf1r,Cflar,Clcf1,Hcls1,Kdr,Ifit3,Il10,Tnfsf14,Birc3,Sirt1,Met,Cd74,Plk3,Cd38,Tnfaip3,Myd88,Rnf34,Traf2,Bcl6,Tnf,Mecp2,Hdac1,Prdx5,Stat3,Nr4a3,Ripk2,Hmox1,Htr2b,Il1b,Kitl,Asns,Higd1a,Ppp1r15a,Pdgfrb,Irf7,Serpine1,Ccl5,Ciapin1,Cx3cl1,Irs2,Nck1,Fas,Stxbp1,Cdkn2d,Cd34,Pim3,Nlrc4,Cited2,Dnaja1,Eif2ak2,Plac8,Sqstm1,Itgav,Sod2,Bcl2a1b,Bnip3,Gclm,Ifit3b,Map2k4,Ptk2,Egr3,Mtdh,Cpeb4,Pim2,Itga5,Mmp9,Cdkn1a,Notch2,Jak2,Arf4,Tax1bp1,Rel,Cav1,Casp8,Ednrb,Nfkb1,Ikbkg,Slc9a1 |
| 5.945e-18 | -39.66 | signaling receptor binding | molecular function | GO:0005102 | 1660 | 208 | 20217 | 1400 |
Socs1,Rtp4,Prkce,Csf1,Lyn,Bmp2,Nr1h3,Nr4a1,Gja1,H2-Q7,Sirt1,Tnfsf15,Cav1,Prdx5,Cd86,Inhba,Mmp14,Cx3cl1,Sipa1l1,H2-M2,Il10,Cxcl9,Flrt3,Ccl4,Osm,Marco,Ccl12,Kif5c,Icosl,Ptk2,Mmp13,Il1b,Ncoa7,Ifna6,Ahr,Lrp4,Stat1,Cxcl1,Src,Ifna2,Stat3,H60b,Igf1r,P2ry2,Il15,Nlgn2,H2-T22,Raet1e,Med13,Uchl1,Il12b,Hilpda,Plat,Nck1,Cxcl14,Ccl22,Itga5,Sema4a,Angpt1,Mdm2,Ccl3,Znrf3,Kdr,Il12rb1,Tyk2,Tnfsf14,Myd88,Nr4a3,Plpp3,Icam1,Fpr2,Vegfc,Ripk2,Sqstm1,Traf5,Fzd1,Tnfsf10,Tlr1,Hmga1,Gdf15,Il1rn,Clcf1,Arf4,Tlr2,Kitl,Pilra,Serpine1,Cxcl10,Insl6,Nampt,Traf1,Isg15,Vcam1,Rnd1,Cxcl11,Spred1,Ifna1,H2-T10,Hspa1a,Thbs1,Fpr1,Clec4d,Dnaja1,Pilrb2,Nsmaf,Ednrb,Arid5a,Pdpn,Ccrl2,Tarm1,Ccl5,Nes,Tgfbi,Jag1,Cflar,Adrb2,Ebi3,S1pr2,Ptpn2,Cd74,Itgb8,Bambi,H2-Q6,Tulp3,C3,Cxcl2,Pilrb1,Plscr1,Sema4c,Dock4,Rpgrip1l,Traf2,Grk3,Plaur,Tlr6,Stap1,Gna15,Hap1,Plcl2,Clec2d,Timp1,Pdgfrb,Tnf,Syk,Jak2,Cd300lf,Traf3ip2,Ikbkg,Fgr,Prnp,Tap2,Snx2,Hck,Tnfsf9,Cdk5r1,Phip,Cxcl3,Ccl9,Edn1,S100a8,Ccl7,Tap1,H2-Q4,Casp8,Spred3,Osgin2,Cdc42ep2,Daxx,Ccl8,Hsd17b7,Rnf14,Ccl2,Ptch1,Ifnb1,Il18,Rapgef2,Il27,Lif,Pf4,Fcgr1,Scyl2,Il1a,Pdgfb,Hif1a,Tnfsf4,Il6,Nr3c1,Klrk1,Saa3,H2-T24,Ifna4,Pdgfc,Itgav,Casp3,Ptprj,Homer1,Ifna5,Ets2,Tnfsf8,Nos2,Sema3c,Tlr9,Notch1,Csf3,Adora2a,Flrt2,Lgals9,Irs2 |
| 5.963e-18 | -39.66 | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_UP | MSigDB lists | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_UP | 176 | 53 | 15632 | 1249 |
Lgals9,Lcp2,Pde7b,Car13,Tlr1,Rilpl1,Pdgfb,Il2rg,Ptgs2,Clec5a,Oas1g,Smox,Slc29a3,Arid5a,Gpr84,Gbp3,Ddx58,Rhoh,Irak3,Cd14,Casp4,Gbp7,Casp8,Pid1,Tnfrsf1b,Rasgrp1,Slamf9,Oas1a,Stat4,Srxn1,Ms4a6d,Chd9,Ccl4,Ets2,Bcl2l11,Slc7a11,Syk,Plac8,Cx3cr1,Il18bp,Pdpn,Rai14,Il4i1,Edn1,Irf4,Nr1h3,Rtp4,Lrp8,Tmem176b,Atf3,Klf7,Fcgr1,Sdc4 |
| 6.094e-18 | -39.64 | enzyme binding | molecular function | GO:0019899 | 2300 | 265 | 20217 | 1400 |
Sod2,Cenpe,Rims3,Slpi,Rnf31,Sipa1l1,Rgl1,Ksr1,Dnajb2,Atp2b4,Egr2,Tnks1bp1,Rac3,Mvp,Ptk2,Socs1,Nod2,Caml,Lyn,Prkce,Notch2,Gja1,Sirt1,Tax1bp1,Bcor,Smg7,Cav1,Rnf19b,Optn,Rab3ip,Slc2a1,Uchl1,Triobp,Nck1,Prdm1,Tpi1,Ppp1r12b,Fas,Angpt1,Mdm2,Marcks,Sdc4,Zc3hav1,Lcn2,Cdkn2d,Sell,Lrp4,Stat2,Stat1,Nfkbia,Etv3,Hmox1,Abr,Itpr1,Hspa2,Src,Mier3,Tpx2,Mid1,Myc,Stat3,Stxbp1,Ehd1,Mul1,Ube2l6,Dennd2a,Dio2,Cd40,Sh3bp4,Tnfaip3,Hmga1,Diaph2,Rnf19a,Tbc1d13,Serpine1,Ccne1,Dusp2,Snx10,Stau1,Trib3,Nr4a3,Dcun1d3,Ripk2,Sqstm1,Traf5,Rffl,Kat2b,Hspa1a,Map2k1,Hk3,Egr1,Ptafr,Fmnl2,Ppp1r15a,Mcm10,Ccng2,Malt1,Dnaja1,Tnfrsf14,Mlkl,Nek6,Rnd3,Ikbke,Tbc1d1,Ppp2r5a,Micall2,Ralgds,Rgcc,Pfkl,Traf1,Acvrl1,Casp1,Txn1,Ctsc,Isg15,Gclm,H2-Ab1,Cenpj,Rnd1,Rapgef5,Rab11fip1,Spred1,Rgs14,Ankib1,Ptgs2,Zmynd15,Dock10,Tulp3,Pml,Rhoq,Arhgef3,Hmga2,Plscr1,Resf1,Bfar,Gch1,Irgm2,Dock4,Wars,Hinfp,Traf2,Relb,Usp25,Plaur,Cacnb3,Ccnd1,Trib1,Cflar,Pla2g4a,Adrb2,Pde3b,Arg2,Ezr,Kdm4a,Ptpn2,Nox1,Ccnj,Actb,Cd74,Tor1aip1,Mecp2,Jak2,Cyfip1,Ikbkg,Rilpl1,Map2k4,Met,Rictor,Fgr,Hdac1,Prnp,Ric1,Cdk5r1,Mcm9,Dtx3l,Parp9,Rhou,Psd,Cdkn1a,Tagap,Stap1,Tnfrsf1b,Eno2,Whamm,Sele,Vcan,Eno1,Plek,Timp1,Mapkapk2,Pdgfrb,Tor1aip2,Tnf,Cpd,Syk,Tank,Cyth3,Bcl2l11,Psd4,Ldlr,Cycs,Akt3,Fzd5,Bnip3,Prkar2b,Hspa1b,Ubash3b,Rnf34,Hif1a,Dennd1b,Ranbp2,Serpinb9,Ppp6r1,Il15ra,Vrk2,Cdc42ep4,Ap3b1,Dusp1,Rabgef1,Casp8,Tnip1,Spred3,Cdc42ep2,Daxx,Rnf14,Rhoh,Dennd6b,Rnf139,Rapgef2,Rhof,Nos2,Ppp2r2a,Notch1,Errfi1,Ccnd2,Spata13,Gys1,Spry2,Adora2a,Dmxl2,Csf3,Lgals9,Rasgrp1,Lipe,Cited2,Parp14,Irs2,Daam1,Nr3c1,Slc9a1,Klrk1,Ddx58,Sphk1,Rhoc,Cacybp,Trim12c,Itgav,Tuba4a,Casp3,Jun,Hcls1,Ptprj,Zfp36,Phactr4,Phf6 |
| 6.133e-18 | -39.63 | regulation of adaptive immune response | biological process | GO:0002819 | 203 | 53 | 20694 | 1406 |
Il6,Traf2,Hlx,Ripk2,Spn,H2-M2,H2-Ab1,Pvr,Nfkbiz,H2-T10,H2-T22,Il12rb1,Il4ra,Tnfaip3,Irf7,Tnfrsf14,Ripk3,Clcf1,H2-Q4,H2-T24,Il18,Sirt1,Zc3h12a,Tnfrsf1b,Lgals9,Cd274,Nlrp3,Il1b,Rsad2,Tnf,Il27,Fcgr1,Irf1,H2-Q6,Tnfsf4,Fcgr2b,Arid5a,Cd40,Nod2,Nfkbid,Ifnb1,Tap2,H2-Q7,Bcl6,Fzd5,Malt1,Samsn1,C3,Cd74,Cd55,Parp3,Nectin2,Il12b |
| 6.133e-18 | -39.63 | negative regulation of cell activation | biological process | GO:0050866 | 203 | 53 | 20694 | 1406 |
Ubash3b,H2-Aa,Socs1,Cx3cl1,Adora2a,Slfn1,Irf1,Milr1,Prdm1,Adrb2,Fcgr2b,Sdc4,Tnfsf4,Il10,Rabgef1,Fas,Nfkbid,Ifnb1,Samsn1,Ptpn2,Bcl6,Pde5a,Gclc,Nr1h3,Parp3,Cst7,Cd74,Arg2,Atm,Pdgfb,Cd80,Hlx,Abr,Prnp,H2-Ab1,Peli1,Spn,Ldlr,Cd86,Casp3,Cd200,Hmox1,Lyn,Tnfaip3,Tnfrsf14,Tarm1,Il4ra,Zc3h12a,Fgl2,Cd300lf,Cd274,Lgals9,Axl |
| 6.306e-18 | -39.61 | GSE6674_UNSTIM_VS_PL2_3_STIM_BCELL_DN | MSigDB lists | GSE6674_UNSTIM_VS_PL2_3_STIM_BCELL_DN | 153 | 49 | 15632 | 1249 |
Scarf1,Vcan,Lrch1,Ccl12,Flrt3,Morc3,Dnase1l3,Cd34,Nr1h3,Nlrp3,P2ry14,Tlr6,Mapkapk2,St3gal3,Fas,Sirt1,Usp12,Cnn3,Cenpj,Sco1,Ppp1r15b,Gfi1,Asf1a,Cd82,Tmem67,Odc1,Ccnd1,Acvr1,Mdm2,Dbnl,Itgb8,Tcf4,Insl6,Ddhd1,Txnrd1,Rhoc,Nod1,Lif,Itga4,Sh3bp4,Phlpp2,Rilpl1,Wdfy1,Tcea1,Plcl2,Elmod2,Il18,Parp3,Hmox1 |
| 7.309e-18 | -39.46 | Cytokine-cytokine receptor interaction | KEGG pathways | ko04060 | 266 | 71 | 7931 | 713 |
Il15,Pdgfrb,Osm,Il6,Ifna4,Il1a,Ccl8,Inhba,Ccl12,Tnfsf9,Csf1,Cxcl14,Cxcl9,Flt1,Cx3cr1,Tnfrsf14,Ccl2,Lif,Tnfrsf8,Csf3r,Ccl5,Tnfsf4,Tnfrsf1b,Ccr3,Ifnar1,Ifna5,Ccl4,Cxcl2,Ccl9,Il12rb1,Cxcl11,Ccl7,Pdgfb,Acvr1b,Il13ra1,Cx3cl1,Il12b,Il1b,Vegfc,Il4ra,Xcr1,Tnfsf15,Met,Ifna6,Pf4,Tnfsf8,Csf3,Ccr1,Pdgfc,Bmp2,Kitl,Il18,Ifnb1,Tnfsf14,Kdr,Il2rg,Ccl22,Tnf,Cxcl10,Fas,Il18rap,Il15ra,Il10,Tnfsf10,Cxcl1,Acvr1,Ifna1,Cd40,Ifna2,Ccl3,Clcf1 |
| 7.309e-18 | -39.46 | Cytokine-cytokine receptor interaction | KEGG pathways | mmu04060 | 266 | 71 | 7931 | 713 |
Pdgfb,Ccl7,Il13ra1,Cx3cl1,Acvr1b,Ifna5,Ifnar1,Ccr3,Il12rb1,Cxcl11,Ccl9,Ccl4,Cxcl2,Tnfrsf8,Lif,Ccl5,Csf3r,Flt1,Cx3cr1,Tnfrsf14,Ccl2,Tnfsf4,Tnfrsf1b,Il6,Il1a,Ifna4,Il15,Osm,Pdgfrb,Cxcl14,Csf1,Cxcl9,Ccl8,Inhba,Tnfsf9,Ccl12,Acvr1,Cxcl1,Tnfsf10,Cd40,Ifna1,Ccl3,Clcf1,Ifna2,Fas,Il18rap,Kdr,Ccl22,Tnf,Cxcl10,Il2rg,Il15ra,Il10,Ccr1,Bmp2,Pdgfc,Pf4,Tnfsf8,Csf3,Ifnb1,Tnfsf14,Kitl,Il18,Il4ra,Xcr1,Tnfsf15,Vegfc,Il12b,Il1b,Ifna6,Met |
| 7.791e-18 | -39.39 | regulation of symbiosis, encompassing mutualism through parasitism | biological process | GO:0043903 | 218 | 55 | 20694 | 1406 |
Chmp4b,Notch1,Isg15,Trim13,Zc3hav1,Irf8,Zc3h12a,Trim30a,Adar,Tlr2,Pcx,Cav1,Oas1g,Itgav,Stat1,Sqstm1,Isg20,Plscr1,Bcl2l11,Trim26,Fam111a,Oasl2,Oas1a,Slpi,Oas1b,Il12b,Nectin2,Cd74,Zfp36,Ifitm1,Ccl5,Trim14,Ifnb1,Nod2,Trim21,Resf1,Stau1,Larp1,Parp10,Trim56,Pml,Il10,Oas3,Myd88,Hdac1,Oasl1,Tnf,Eif2ak2,Mdfic,Jun,Shfl,Cxcl1,Rsad2,Apobec3,Ccl4 |
| 8.952e-18 | -39.25 | REACTOME_INTERFERON_GAMMA_SIGNALING | MSigDB lists | REACTOME_INTERFERON_GAMMA_SIGNALING | 64 | 31 | 15632 | 1249 |
Gbp2,Ciita,Fcgr1,Icam1,Socs1,Gbp3,H2-Q7,Irf2,Pml,Irf4,Gbp4,Gbp9,H2-Q6,Ptpn2,Oas3,H2-Q4,Jak2,Vcam1,Irf1,Ptafr,Oasl1,Socs3,Stat1,Oas1g,Oas1a,Oas2,H2-Aa,Irf8,Gbp7,Irf7,H2-Eb1 |
| 9.347e-18 | -39.21 | regulation of cellular component organization | biological process | GO:0051128 | 2480 | 276 | 20694 | 1406 |
Srgn,Pmepa1,Rgcc,Notch2,Tmem67,Rnd1,Agrn,Mefv,Mark2,Ppp1r15a,Cd14,Bnip3,Bcl6,Gdf15,Cx3cl1,P2ry2,P2ry12,Kdr,Pla2g4a,Arid5a,Katna1,Etv5,Sdc4,Fcgr2b,Siglece,Cdkn1a,Pikfyve,Irgm1,Acvrl1,Met,Tnfsf10,H3f3b,Nck1,Dcbld2,Tnfsf14,Cdk5r1,Psmd10,Prkce,Crlf3,Gja1,Rhof,Asap3,Hk2,Il1b,Pttg1,Pmaip1,Palld,Mdm2,Mid1,Vasp,Cflar,G3bp2,Acvr1b,Hif1a,Il6,Kdm4a,Ddhd1,Sema4a,Prnp,Plek,Fbxo4,Nrp2,Plk2,Prdm9,Nupr1,Igsf9,Spry2,Dnajb2,Ntng2,Sipa1l1,Triobp,Rhoq,Birc2,Hspa2,Antxr1,Ifrd1,Prag1,Rac3,Nr1h3,Rab3ip,Ptk2,Dync1i2,Gda,Pdgfrb,Fzd5,Ccl8,Myc,Myo10,Pdpn,Rhou,Eif2ak2,Cenpj,Mecp2,Dcun1d3,Sdc2,Scyl2,Mllt6,Ezr,Ccl2,Slc9a1,Fcgr1,Dcp2,Apaf1,Adrb2,Evl,Mpp7,Inhba,Rictor,Stat1,Bcor,Tlr6,Flrt3,Rap1gap2,Sphk1,Crkl,Mndal,Swap70,Tnfrsf1b,Optn,Piezo1,Lpar1,Cxcl10,Xaf1,Dst,Lif,Pdgfb,Hcls1,Eif4g2,Map2k1,4932438A13Rik,Lcn2,Lst1,Stat2,Bcl2l11,Hck,Src,Sema3c,Nr3c1,Rabgef1,Icam1,Jdp2,Kat2b,Cdkn2d,Wars,Phip,Nox1,Dync1h1,Dr1,Fgr,Nlgn2,Igf1r,Parp3,C3,Fscn1,Sec24b,Zswim4,Tnf,Il1a,Ccl3,Daxx,Fam162a,Trim36,Fzd1,Stxbp1,Bambi,Sh3bp4,Tpx2,Syk,Ccl12,Parp10,Sertad3,Pml,Brwd3,Rab20,Kif9,Angpt1,Ikzf1,Trim30a,Myadm,Sdc1,Ahr,Spire1,Cav1,Lyn,Slc7a11,Il4ra,Osm,Kremen1,Lmo4,Itpr1,Rims3,F11r,Dbnl,Il15ra,Axl,Gpsm2,Ier3,Sirt1,Mmp9,Arf4,Syne2,Higd1a,Atm,Cyfip1,Adgrl2,Whamm,Hspa1b,Cd38,Hsph1,Rapgef2,Nsd3,Lrp8,Fas,Tmsb10,Serpine1,Carmil1,Flrt2,Stap1,Edn1,Resf1,Sema4c,Homer1,D16Ertd472e,Trip13,Rhoc,Phldb1,Mmp14,Irak3,Aim2,Fchsd2,Tspo,Ehd1,Hspa1a,Cenpe,Lnpk,Kif3c,Bst1,Ptger4,Mov10,Plaur,Rab21,Il10,Cdc42ep4,Fmnl2,Ust,Rnd3,Tlr2,Osgin2,Crbn,Scarf1,Rhoh,Chmp4b,Notch1,Trip10,Sele,Gfi1,Tomm70a,Smc5,Tmod3,Lrp4,Mul1,Irgm2,Mthfr,Scn1b,Cxcl9,Nek6,Ptprj,Smg7,Ldlr,Tlk2,Hap1,Jarid2,Gng4,Csf3,Cdc42ep2,Map4k4 |
| 9.782e-18 | -39.17 | GO_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | MSigDB lists | GO_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | 111 | 41 | 15632 | 1249 |
Ifi207,Tnfaip3,Zc3hav1,Relb,Myd88,Zbp1,Cd14,Ddx58,Ifi214,Rnf135,Ifih1,Isg15,Dhx58,Ifi205,Ifi209,Ifi213,Nlrc5,Ifnar1,Syk,Tax1bp1,Ikbke,Nfkb2,Ifi204,Irf1,Tlr2,Tlr3,Tlr9,Ripk2,Trim56,Ifi203,Uba7,Ube2l6,Ifi211,Trim21,Nmi,Ifi208,Il10,Rel,Irf7,Mndal,Nfkb1 |
| 1.024e-17 | -39.12 | GSE17721_LPS_VS_PAM3CSK4_6H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_6H_BMDC_UP | 190 | 55 | 15632 | 1249 |
Rnf114,Spsb1,Crbn,Triobp,Evl,Arl4a,Rtp4,Nxf1,Phip,Tspo,Hk1,Rnf14,Tifa,Nfkbib,Tmod3,Tnfsf4,Tax1bp1,Notch2,Plekhn1,Ddhd1,Casp1,Gpsm2,Hspa1a,Timp1,Ccdc86,Cish,Tbc1d1,Nr3c1,1110038F14Rik,Mcm10,Itga4,Irf2,Sertad3,Cutc,Sgk3,Myd88,Sesn3,Atp6v1d,Tap2,Slfn4,Noc4l,Wdfy1,Pde7b,Dgka,St3gal1,Rnf19b,Serpinb9,Pim1,Kitl,Slfn3,Gtpbp2,Plcl2,Ppp2r2a,Sec24b,Pkp4 |
| 1.036e-17 | -39.11 | GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_DN | MSigDB lists | GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_DN | 178 | 53 | 15632 | 1249 |
Itpkc,Ppa1,Dram1,Ifi35,Casp7,Slc25a22,Irf1,Jak2,Hk1,Psmb8,Lap3,Irf8,Plscr1,Isg20,Egln3,Atf3,Fas,Il15,Pilra,Tap1,Rnf114,Ccl12,Spsb1,Morc3,Dock4,S1pr2,Optn,Rnf19b,Atp10a,Cxcl10,Arid5b,Ptafr,Cdc42ep4,Ak4,Cxcl1,Trafd1,Il15ra,Gch1,Plekha4,Icosl,Ube2l6,Oas2,Maff,Stoml1,Wars,Socs1,Psmb10,Icam1,Gbp2,Cd40,Psmb9,Cish,Egr2 |
| 1.036e-17 | -39.11 | GSE42724_NAIVE_VS_MEMORY_BCELL_UP | MSigDB lists | GSE42724_NAIVE_VS_MEMORY_BCELL_UP | 178 | 53 | 15632 | 1249 |
Cflar,Tnip1,Ppfibp2,Dgkh,Tlr9,Stat1,Acvr1b,Gpd2,Pdzd11,Cysltr2,Rasgrp1,Birc3,Marco,Lmo4,Gbp7,Kif9,Fcgr1,Dusp14,Samhd1,Nck1,Coa5,Nlrp3,Il4i1,Msr1,Hmga1,Dnaja1,Cmklr1,Ralgds,Tnfsf10,Irak2,Dcbld2,Il1b,Glrx,Hcar2,Hp,Ptgs2,Adora2b,Caml,Txn1,Rgl1,Gch1,Ppp1r15a,Cd38,Gbp2,Psmb10,Rab11fip1,Setdb2,Nfkbie,Gsr,Hsph1,Ehd1,Ifnar1,Gypc |
| 1.038e-17 | -39.11 | GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_DN | MSigDB lists | GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_DN | 184 | 54 | 15632 | 1249 |
Cd14,Crlf3,Myd88,Gbp2,Myo10,Rab3ip,Nupr1,Ifih1,Usp18,Ccdc86,Ythdf1,Cebpd,Inpp1,Il1rn,Cmpk2,Hmox1,Pcgf5,Crkl,Rnf19b,Grina,Ext1,Caml,Uba7,Klf2,Il15,Samhd1,Tnks1bp1,Chmp4b,Mark2,Pgm1,Cox17,Sod2,Ccl12,Ezr,Gadd45b,Map3k6,Hmga1,Ptpn2,Spic,Znfx1,Jak2,Wdr43,Dck,Il13ra1,Mthfd2,Ifit3b,Ampd3,Plscr1,Slpi,Isg20,Pdk3,Lmo4,Ogfr,Ifit3 |
| 1.163e-17 | -38.99 | RUTELLA_RESPONSE_TO_HGF_DN | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_DN | 209 | 58 | 15632 | 1249 |
Myd88,Cd83,Traf5,Cd14,Irak3,Marcksl1,Itga4,Sell,Rab11fip1,Pnp2,Fchsd2,Ccng2,Cebpd,Rsad2,Casp1,Plekha5,Acpp,Plcl2,Sp110,Zhx2,Cd55,Fpr1,Ddit4,H2-Aa,Spint2,Nampt,Dusp6,Map4k4,Tuba4a,Rnaset2a,Cd86,Pgs1,Bcor,Egr1,Nlrp3,Peli1,Vcan,Map3k6,Eif2ak2,Gadd45b,Aoah,Cx3cr1,Plac8,Ets2,Notch2,Adam19,Trem1,Rnaset2b,Cdkn1a,Il13ra1,Ms4a6d,Zfp36,Plscr1,Egln3,Rap1gap2,Itgal,Pid1,Sik3 |
| 1.217e-17 | -38.95 | cellular developmental process | biological process | GO:0048869 | 3848 | 387 | 20694 | 1406 |
Ifna5,Rilpl1,Tmod3,Lrp4,Mul1,Hlx,Hsd17b7,Clec5a,Tut7,Casp4,Rrs1,Ldlr,Casp1,Jarid2,Micall2,Hap1,Foxp4,Gpr18,Zc3h12a,Sgcb,Scarf1,Gfi1,Trip10,Kif3c,Usp42,Plpp3,Tspo,Irf1,Map2k4,Intu,Rab21,Asf1a,Cnp,Cx3cr1,Sema4c,Edn1,Rai14,Trip13,Socs7,Fas,Frmd6,Irf4,Itga4,Sav1,Casz1,Ddx4,Cyfip1,Ptgs2,Ier2,Bcl9,Syne2,Mmd,Plscr1,Spn,Pik3cd,Rapgef2,Rap2c,Marf1,Samd9l,Itpr1,F11r,Dbnl,Sqstm1,Tagln,Spire1,Pbx1,Myadm,Klf7,Cav1,Sirt1,Etv3,Plcl2,Il15ra,Stxbp1,Cited2,Il1a,Tnf,Rsad2,Tcf4,Jun,Angpt1,Ikzf1,Taf4b,Rasgrp1,Ccl12,Atf3,Psd,Rbl1,Mycl,Nlgn2,Icam1,Jmjd6,Kat2b,Uchl1,Arid5b,Insl6,Col27a1,Tnfaip2,Pou3f1,Vcan,Flt1,Lif,Gpc1,Heatr9,Nr3c1,Map2k1,Dock10,Eif4g2,Snx10,Fpr2,Jak2,Tcea1,Rap1gap2,Sphk1,Inhba,Tnfaip3,Tnfrsf1b,Plac8,Rgs14,Ifna2,Tnc,Arid4a,Socs3,Kif5c,Apobec3,Herc6,Golga3,Azi2,Pnpt1,Plagl1,Pdpn,Socs1,Stat5a,Batf,Ccl2,Adrb2,Evl,Slamf8,Psmb8,Sipa1l1,Ifrd1,Antxr1,Hspa2,Spen,Il15,Nupr1,Csf1,Igsf9,Col18a1,Cebpd,Pdgfrb,Fzd5,Ptpn2,Nr1h3,Tle3,Prag1,Prkx,Rac3,Etv6,Ptk2,Nfkb2,Phgdh,Lox,Tnfsf9,Nrp2,Lhx2,Bmp2,Casp2,Cdk5r1,Ifna1,Lrrc8c,Btg2,Sla,Diaph2,Il1b,Tet2,Cacybp,P2ry2,P2ry12,Slfn5,Acvrl1,Ifna6,Nck1,Sdc4,Katna1,Etv5,Casp8,Pikfyve,Cdkn1a,Tmem67,Mosmo,Clic4,Slc7a5,Psmb10,Ednrb,Bnip3,Agrn,Il12b,Htra1,Spred1,Scn1b,Smc5,Ifna4,Csf3,Map4k4,Tnfsf8,Ptprj,Tlk2,Flnb,Tdrd7,Tlr2,Clec4d,Clec4e,Cd300lf,Tiparp,Notch1,Rhoh,Pid1,Ets2,Mov10,Ptger4,Abcb1a,Adora2a,Rnf114,Ehd1,Adgrg6,Ust,Hdac1,Nr4a1,Hinfp,Acvr1,Plaur,S100a8,Homer1,Xrn1,Tsku,Stap1,Tent2,D16Ertd472e,Lrp8,Flrt2,Tmem176b,Serpine1,Gadd45g,Nectin2,Hivep3,Itgb8,Clic5,Morc3,Nes,Atm,Fos,Bcl2a1d,Rmdn3,Mturn,Cdyl,Cd38,Lmo4,Ptch1,Htr2b,Rab32,Clcf1,Parp11,Sdc1,Ahr,Kremen1,Chst11,Lyn,Arf4,Csrp1,Fam20c,Hhex,Irf8,Axl,Gpsm2,Syk,Snx2,Ccl3,Zswim4,Fzd1,Sod2,Prdm1,Pml,Ccr1,Igf1r,Fndc3a,Fgr,Ccl5,Ifnb1,Junb,Actb,Malt1,Sec24b,C3,Cd74,Pdgfb,Klrk1,Dst,Ero1l,Arl4a,Batf2,Lpar1,Stat3,Hck,Src,H2-Ab1,Sema3c,4932438A13Rik,Hcls1,Lst1,Spint2,Stat1,Flrt3,Crkl,Ripk3,Maff,Adar,Dnase1l3,Pou2f2,Phactr4,Vegfc,Tulp3,Mecp2,Hopx,Spic,Slc9a1,Ddit4,Sdc2,Ezr,Ntng2,Triobp,Klf2,Spry2,Myc,Zeb1,Dync1i2,Ppp4r2,Hif1a,Itga5,Kdm4a,Il6,Jag1,Sap30,Cflar,Vasp,Plk2,Sema4a,Itgav,Gja1,Casp3,Nr4a3,Ccnd1,Relb,Zmynd15,Palld,Mdm2,Hmga2,Ppp2r3a,Fubp1,Kdr,Egr2,Col11a2,Cx3cl1,Kitl,Myd88,Met,Zfp281,H3f3b,Fcgr2b,Arid5a,Vcam1,Ext1,Rab10,Egr1,Notch2,Zhx2,Pdlim7,Slc4a7,Fabp7,Gdf15,Bcl6,Plod3,Gadd45b,Rnd1,Kdm6b,Mark2,Rcan1 |
| 1.326e-17 | -38.86 | cell differentiation | biological process | GO:0030154 | 3711 | 376 | 20694 | 1406 |
Lrp4,Mul1,Hlx,Tmod3,Rilpl1,Ifna5,Micall2,Hap1,Casp1,Jarid2,Ldlr,Rrs1,Casp4,Tut7,Clec5a,Hsd17b7,Gpr18,Foxp4,Trip10,Gfi1,Scarf1,Sgcb,Zc3h12a,Tspo,Plpp3,Usp42,Kif3c,Cx3cr1,Asf1a,Rab21,Cnp,Intu,Map2k4,Irf1,Frmd6,Fas,Socs7,Rai14,Trip13,Edn1,Sema4c,Sav1,Itga4,Irf4,Syne2,Bcl9,Mmd,Ier2,Ptgs2,Ddx4,Cyfip1,Casz1,Rap2c,Marf1,Pik3cd,Rapgef2,Spn,Plscr1,Klf7,Cav1,Myadm,Pbx1,Spire1,Dbnl,Sqstm1,Tagln,Itpr1,Samd9l,F11r,Il15ra,Plcl2,Etv3,Sirt1,Tcf4,Jun,Rsad2,Tnf,Il1a,Cited2,Stxbp1,Atf3,Rasgrp1,Ccl12,Taf4b,Angpt1,Ikzf1,Uchl1,Kat2b,Jmjd6,Icam1,Nlgn2,Mycl,Psd,Rbl1,Pou3f1,Tnfaip2,Col27a1,Arid5b,Insl6,Heatr9,Gpc1,Lif,Flt1,Vcan,Fpr2,Snx10,Eif4g2,Map2k1,Dock10,Nr3c1,Inhba,Tnfaip3,Rap1gap2,Sphk1,Tcea1,Jak2,Rgs14,Plac8,Tnfrsf1b,Stat5a,Pdpn,Socs1,Plagl1,Azi2,Herc6,Golga3,Apobec3,Kif5c,Arid4a,Socs3,Tnc,Ifna2,Psmb8,Slamf8,Adrb2,Evl,Batf,Ccl2,Igsf9,Col18a1,Nupr1,Csf1,Il15,Spen,Hspa2,Antxr1,Ifrd1,Sipa1l1,Ptk2,Prag1,Rac3,Prkx,Etv6,Nr1h3,Tle3,Pdgfrb,Cebpd,Ptpn2,Fzd5,Phgdh,Lox,Nfkb2,Casp2,Bmp2,Nrp2,Lhx2,Tnfsf9,Cdk5r1,Tet2,Diaph2,Il1b,Sla,Btg2,Lrrc8c,Ifna1,P2ry12,P2ry2,Cacybp,Casp8,Katna1,Etv5,Sdc4,Ifna6,Nck1,Acvrl1,Slfn5,Slc7a5,Mosmo,Clic4,Tmem67,Il12b,Agrn,Bnip3,Ednrb,Ifna4,Scn1b,Spred1,Htra1,Ptprj,Tlk2,Tnfsf8,Map4k4,Csf3,Clec4e,Tlr2,Clec4d,Flnb,Tdrd7,Rhoh,Notch1,Cd300lf,Tiparp,Ehd1,Rnf114,Adora2a,Abcb1a,Mov10,Ptger4,Ets2,S100a8,Nr4a1,Plaur,Hinfp,Acvr1,Hdac1,Ust,Adgrg6,Tmem176b,Flrt2,Lrp8,Tent2,D16Ertd472e,Tsku,Stap1,Homer1,Itgb8,Clic5,Nectin2,Hivep3,Gadd45g,Rmdn3,Mturn,Fos,Bcl2a1d,Atm,Cd38,Cdyl,Chst11,Lyn,Kremen1,Parp11,Ahr,Sdc1,Clcf1,Rab32,Htr2b,Ptch1,Lmo4,Axl,Irf8,Gpsm2,Hhex,Arf4,Fam20c,Csrp1,Sod2,Fzd1,Zswim4,Ccl3,Syk,Pml,Ccr1,Prdm1,Ifnb1,Ccl5,Fgr,Fndc3a,Igf1r,C3,Cd74,Sec24b,Malt1,Actb,Junb,Lpar1,Arl4a,Batf2,Dst,Ero1l,Pdgfb,Klrk1,Lst1,Hcls1,4932438A13Rik,Sema3c,H2-Ab1,Hck,Stat3,Src,Adar,Maff,Ripk3,Crkl,Stat1,Flrt3,Spint2,Pou2f2,Dnase1l3,Hopx,Mecp2,Tulp3,Vegfc,Phactr4,Ezr,Ddit4,Sdc2,Slc9a1,Spic,Spry2,Klf2,Ntng2,Triobp,Ppp4r2,Dync1i2,Zeb1,Myc,Vasp,Sap30,Cflar,Jag1,Il6,Kdm4a,Hif1a,Itga5,Sema4a,Plk2,Zmynd15,Relb,Ccnd1,Nr4a3,Itgav,Gja1,Casp3,Fubp1,Hmga2,Ppp2r3a,Mdm2,Palld,Kitl,Cx3cl1,Col11a2,Kdr,Egr2,Arid5a,Fcgr2b,Zfp281,H3f3b,Myd88,Met,Zhx2,Notch2,Rab10,Egr1,Ext1,Vcam1,Rcan1,Mark2,Rnd1,Kdm6b,Gadd45b,Bcl6,Plod3,Gdf15,Fabp7,Slc4a7,Pdlim7 |
| 1.330e-17 | -38.86 | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_DN | MSigDB lists | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_DN | 191 | 55 | 15632 | 1249 |
Bcl2a1a,Tfec,Acp2,Trafd1,Ptprj,Traf3ip2,Ripk2,Ptgs2,Ak4,Serpinb9,Il2rg,Il18,Ptafr,Adora2a,Pde4b,Gch1,Batf,Crim1,Tnfaip3,Hck,Nr3c1,Rhoq,Fchsd2,Bcl2a1d,Psma6,Ehd1,Stat5a,Casp1,N4bp1,Cd40,Cflar,Tnip1,Ccl4,Pim2,Stat1,Socs3,Lyn,Plscr1,Ampd3,Stat4,Cd69,Birc3,Nfkb1,Cd80,Adar,Rars,Il4ra,Dmxl2,Ggct,Igsf6,Dusp2,Rin2,Nfkbia,Flt1,Bcl2a1b |
| 1.355e-17 | -38.84 | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP | MSigDB lists | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP | 185 | 54 | 15632 | 1249 |
Nek6,Palld,Plagl1,Ccl22,Prnp,Papss2,Col4a2,Lpcat2,Gng11,Gpc1,Gadd45b,Tagln,Bcl2a1b,Cyfip1,Tspan3,Slc44a1,Chst11,Dusp4,C3,Mmp9,Fscn1,Tnfaip2,Abcc1,Irf8,Casp4,Pstpip2,Alas1,Htra1,Tmem176a,Marcksl1,Icam1,Usp18,Cd83,Gnb4,Relb,Axl,Swap70,Ttc39c,Hspa1a,Ogfrl1,Bcl2a1d,Rnf19b,Nr4a3,Serpinb9,Bcl2a1a,Pkp4,Plek,Gja1,Ccl5,Cd86,Asns,Nrp2,H2-Aa,Tmem26 |
| 1.355e-17 | -38.84 | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_UP | 185 | 54 | 15632 | 1249 |
Usp42,Nr4a3,Rcl1,Glrx,Il1b,Tfec,Snn,Txn1,Tshz1,Tap2,Med21,H2-Aa,Fzd1,Ier2,Fam133b,Calcrl,Slco3a1,Sertad3,Crlf3,Swap70,Birc2,Carhsp1,Cdyl2,Tnfsf4,Acvr1b,Orai2,Tnfaip2,Gfi1,Abcc1,Psmb8,Rnf31,Dcun1d3,Hdc,Bcorl1,Ociad1,St3gal5,Plscr1,Palld,Tlr6,Phip,Trim13,Cd34,Hinfp,Adar,Samhd1,Flt1,Agrn,Cyfip1,Gpr18,D16Ertd472e,Ikzf1,Aftph,Il4i1,Parp9 |
| 1.360e-17 | -38.84 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | 179 | 53 | 15632 | 1249 |
Gbp2,Rhoc,Ch25h,Sertad3,Trim12c,Arg2,Calcrl,Ddx58,Egr2,Ccng2,Rbpms,Klf6,Ifi213,Ifi209,Ifi205,Nfkb2,Serpinb2,Plat,Bambi,Hmox1,Uchl1,Serpinb9,Arid5b,Kif3c,Ifi208,Phlda1,Gdf15,Dusp6,Pde4b,Irf7,Samsn1,Ahr,Ppfibp1,Ifi207,Palld,Tmem176b,Ifi214,Nqo1,Optn,Vcan,Slc7a11,Rgs1,Il13ra1,Cd200,Tnfsf4,Dram1,Ifi204,Ifi211,Procr,Stx6,Cd69,Ifi203,Mndal |
| 1.397e-17 | -38.81 | regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043122 | 166 | 47 | 20694 | 1406 |
Angpt1,Myd88,Tnfsf10,Tlr9,Hdac1,Pim2,Casp8,Cx3cr1,Il1a,Cx3cl1,Tnf,Card6,Mapkbp1,Rnf31,Traf3ip2,Il1rn,Cd74,Mtdh,Ankrd17,Tnip3,Nod2,Nod1,Nfkbid,Tank,Peli1,Casp1,Traf2,Tab2,Tifa,Ripk2,Sirt1,Zc3h12a,Optn,Clec4n,Il1b,Rhoh,Zc3hav1,Trim13,Ikbkg,Stat1,Tlr6,Tlr3,Sqstm1,Traf5,Prkce,Tnip1,Tnfaip3 |
| 1.470e-17 | -38.76 | ISRE_01 | MSigDB lists | ISRE_01 | 229 | 61 | 15632 | 1249 |
Ifit3b,Mmp25,Kpna3,Etnk1,Ptch1,Sik3,Ifit3,Mov10,Etv6,Met,Xaf1,Med13,Atxn7l1,Tifa,Trim21,Rtp4,Ddx60,Zbp1,Il27,Gpr18,Gsdmd,Ifnb1,Optn,Bbx,Cxcl10,Pcgf5,Ripk2,5430427O19Rik,Pgk1,Epsti1,Thbs1,Pcdh7,Osm,Jarid2,Dgka,Uba7,Eya4,Tnfsf15,Dtx3l,Pigv,Isg15,Ifih1,Ddx58,Kdm4a,Usp18,Pml,Irf2,Tsku,Etv5,Sla,Gnb4,Homer1,Armcx6,Ifit2,Parp8,Atp13a1,Tapbp,Dhx58,Batf2,Egr2,Ifi44 |
| 1.532e-17 | -38.72 | regulation of leukocyte migration | biological process | GO:0002685 | 200 | 52 | 20694 | 1406 |
Crkl,Lyn,Sell,Tnfrsf14,Gpr18,Cd200,Tnfsf14,Tlr2,Ripk3,Swap70,Mmp9,Lgals9,Sele,Il1b,Cxcl10,Ptafr,Dusp1,Lrch1,Abr,Thbs1,Spn,Mtus1,Fpr2,Ptprj,Edn1,Cxcl14,Stap1,Serpine1,Nod2,Pla2g7,Rabgef1,Ccl5,Csf1,Icam1,Itga4,Mmp14,Cd74,Ptger4,Vegfc,Ccl4,Cmklr1,Bst1,P2ry12,Kitl,Cx3cl1,Il1a,Slamf8,Myd88,Ccl2,Ccr1,Ccl12,Tnfsf4 |
| 1.698e-17 | -38.61 | negative regulation of molecular function | biological process | GO:0044092 | 1082 | 150 | 20694 | 1406 |
Mmp9,Sirt1,Mdm2,Il1b,Hhex,Hp,Cnn3,Trib3,F11r,Casp3,Acod1,Ptch1,Pbx1,Ahr,Tnfsf14,Psmd10,Keap1,Lyn,Cav1,Ppp2r5a,Nfkb1,Prnp,Rab9,Plscr1,Hspa1b,Dusp5,Fam72a,Lhx2,Thbs1,Tax1bp1,Cacnb3,Marf1,Ppp1r12b,Gem,Dusp2,Stoml1,Dusp1,Il6,Slpi,Dusp8,Ptgs2,Bcl2a1d,Cflar,Ifit2,Actb,Ppp1r15a,Nqo1,Dusp4,Aida,Agrn,Gadd45b,Spred3,Parp3,P2ry13,Cst7,Cd55,C3,Wars,Igf1r,Serpinb9,Crim1,Uchl1,Cdkn2d,Irs2,Kat2b,Gpr35,Met,Nck1,Parp10,Pim2,Cdkn1a,Pml,Dusp6,Nlrc5,Sh3bp4,Ubash3b,Tnf,Rffl,Jun,Zc3h12a,Irak2,Rhoh,Serpinb9b,Nlrp3,Notch1,Rgs14,Gfi1,Prdx5,Jak2,Timp1,Spint2,Errfi1,Nfkbib,Cd200,Adar,Pim1,Hmox1,Trib1,Tnfaip3,Peli1,Mitd1,Src,Nfkbil1,Ptprj,Arg2,Pdgfb,Spred1,Serpina3f,Serpinb6b,Mvp,Lrch1,Parp9,Ptpn2,Zfp36,Itga4,Irak3,Myc,Dtx3l,Gadd45g,Med13,Serpinb2,Trim21,Birc2,Dusp16,Dnaja1,Prkar2b,Nupr1,Spry2,Serpine1,Nfkbid,Nod2,Dnajb2,Ppp1r14b,Adrb2,Tlr9,Nfkbia,Plaur,Nr4a1,Tnfsf4,Birc3,Il10,Cmklr1,Rnf34,Mecp2,Phactr4,Atp2b4,Socs1,Serpina3g,Aim2,Adora2a |
| 1.725e-17 | -38.60 | regulation of leukocyte proliferation | biological process | GO:0070663 | 236 | 57 | 20694 | 1406 |
Cd274,Hhex,Il1b,Lgals9,Il18,Itgal,Tnfrsf1b,Ripk3,Clcf1,Ahr,Il12rb1,Tarm1,Tnfrsf14,Lyn,Casp3,Cd86,Icosl,H2-Ab1,Peli1,Prnp,Tnfsf9,Spn,Cd38,Ripk2,Arg2,Cd80,Atm,Il6,Il12b,Cd74,Ccdc88b,Bcl6,Pde5a,Il15,Csf1,Ccl5,Irs2,Vcam1,Cd40,Sdc4,Tnfsf4,Fcgr2b,Ccl12,Il10,Cdkn1a,Myd88,Irf1,Tlr9,Prdm1,Il27,Nck1,Slfn1,Stat5a,Kitl,Bst1,H2-Aa,Syk |
| 1.765e-17 | -38.58 | GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_DN | MSigDB lists | GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_DN | 186 | 54 | 15632 | 1249 |
Hmga1,Tiparp,Ezr,Nqo1,Dusp2,Arl4a,Mapkapk2,Atf3,Olr1,Gem,Tnfsf14,Gna15,Nfkb1,S100a8,Eno2,Mmd,Ampd3,Ier3,Tnip1,Ccl4,Orai2,Plod3,Phldb1,Slc16a3,Txnrd1,Dusp1,Tnfsf8,Rab9,Pnp2,Traf1,Cd180,Upp1,Tulp3,Marcksl1,Tnfaip3,Cd83,Fosb,Serpine1,Flrt2,Ppp1r15a,Brd2,Csrp1,Slc4a7,Slc7a5,Icosl,Ddit4,Cdc42ep4,Tgfbi,Il1b,Plaur,Serpinb2,Thbs1,Inpp1,Cxcl1 |
| 1.782e-17 | -38.57 | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | MSigDB lists | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | 180 | 53 | 15632 | 1249 |
Etnk1,Pdzd11,Vrk2,Tor3a,Rnf14,Ubr4,Ogfr,Csf1,Nfkbib,Ppp4r2,Hivep3,Nck1,Fas,Arl4a,P2ry14,Slc25a25,Sgcb,Rras2,Dusp2,Ncoa5,Ift57,Parp9,Tlr3,Prdm9,Gtpbp2,Pcdh7,Tnfsf10,Cldnd1,Stip1,Sp110,Slc7a8,Csrp1,Cnp,Rrs1,Sap30,Rab10,Pdlim7,G3bp2,Wars,Cxcl2,Tyk2,Ch25h,Rnf135,Ifih1,Sertad3,Bfar,Sav1,Prpf38a,Gypc,Spryd7,Tbc1d1,Batf2,Egr2 |
| 1.898e-17 | -38.50 | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | MSigDB lists | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | 375 | 82 | 15632 | 1249 |
F10,Cd34,Pfkfb3,Samhd1,Zc3hav1,Me1,Atf3,Col18a1,Egr1,Nr1h3,Papss2,Tpx2,Spry2,Rai14,Myc,Peli1,Gadd45g,Nqo1,Gadd45b,Nfkbia,Sod2,Slc7a11,Ccl12,Ets2,Jun,Gfpt1,Prkar2b,Oasl1,Irf1,Trib1,Zfp36,Met,Tmem176a,Psat1,Ednrb,Rel,Gem,Cd83,Bmp2,Gbp2,Tnfaip3,Myo10,Itga4,Ifih1,Rnd1,Egr2,Ifi44,Fgl2,Klf6,Dusp1,Slc16a3,Txnrd1,Mtus1,Cd302,Cxcl1,Acsl5,Vcam1,Tnfsf10,Thbs1,Il15ra,Pgk1,Abcc4,Tlr3,Slc31a1,Uchl1,Slc43a3,Trib3,Map3k8,Lox,Cxcl10,Btg2,Phlda1,Slc7a5,Wars,Inhba,Cxcl2,Junb,Nampt,Gdf15,Asns,Ppp1r15a,Serpine1 |
| 1.901e-17 | -38.50 | ZHU_CMV_ALL_UP | MSigDB lists | ZHU_CMV_ALL_UP | 118 | 42 | 15632 | 1249 |
Dnaja1,Eno1,Ifit1bl1,Nfkbia,Nr4a1,Psma6,Ifnb1,Il6,Pnp2,Pla2g4a,Isg15,Trim12c,Egr1,Pml,Irf2,Tap1,Tnfaip3,Mark2,Ccl5,Nfkb1,Tuba4a,Gch1,Ifit1bl2,Eno2,Psmb8,Nampt,Oas2,Wars,Slc39a14,Oas1a,Alas1,Slc7a5,Trim21,Trim26,Nr4a3,Cxcl10,Irf1,Ptgs2,Pim1,Oas1g,Cd55,Stip1 |
| 2.027e-17 | -38.44 | GO_NEGATIVE_REGULATION_OF_CELL_COMMUNICATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_COMMUNICATION | 1093 | 168 | 15632 | 1249 |
Tlr3,Psmb6,Hmox1,Il1b,Htr2b,Plek,Ccl5,Myadm,Dusp6,Ppp1r15a,Flrt2,Serpine1,Osm,Ddit4,Sh3bp4,Inhba,Vasn,Fzd1,Ppp2r3a,Prdm1,Tulp3,Cd74,Psmb10,Rnf34,Cd14,Rgs3,Cd38,Irak3,Tsku,Tnfaip3,Tnf,Traf2,Bcl6,Rab11fip1,Hdac1,Errfi1,Dhx58,Tlr9,Ptgir,Mmp9,Tnip3,Trib1,Lyn,Rpgrip1l,Dusp16,Pmepa1,Atm,Ppp1r15b,Cav1,Pid1,Casp8,Psme2,Nfkbib,Med13,Nck1,Fas,Cdkn2d,Stxbp1,Ubash3b,Mul1,Slc30a1,Cx3cl1,Nr1h3,Znrf3,Pim3,Gpc1,Tspo,Spred1,Dusp14,Itgav,Sod2,Dnaja1,Ptpn2,Gclm,Dusp2,Stap1,Mmp14,Phlpp1,Optn,S1pr2,Dusp4,Phactr4,Ptprj,Scyl2,Zc3h12a,Dusp5,Uchl1,Ptgs2,Grina,Il1rn,Plcl2,Tnfsf10,Bambi,Thbs1,Plaur,Pf4,Plk2,G3bp2,Nfkbid,Hhex,Nfkbil1,Psme1,Lif,Rhoh,Il1a,Icam1,Hif1a,Socs1,Bfar,Bmp2,Notch1,Src,Hsph1,Dusp1,Lrp4,Psmb9,Rgs14,Itpr1,Hspa1a,Rffl,Dusp8,Cish,Mdm2,Acvr1,Ccnd1,Psma6,Socs3,Stat1,Aida,Adrb2,Cflar,Tnip1,Rgs1,Igf1r,Pfkl,Socs7,Rabgef1,Psmb8,Il10,Ptch1,Htra1,Smpdl3b,Sirt1,Atf3,Egr1,Prnp,Phip,Nlrp3,Adar,Htr2a,Gclc,Pde3b,Chmp4b,Atp2b4,Cx3cr1,Ezr,Nlrc5,Nfkbia,Flrt3,Psmd10,Edn1,Irf4,Spry2,Myc,Il6,Ncoa5,Il18bp,Chst11 |
| 2.041e-17 | -38.43 | HELLER_SILENCED_BY_METHYLATION_UP | MSigDB lists | HELLER_SILENCED_BY_METHYLATION_UP | 250 | 64 | 15632 | 1249 |
Fscn1,Ldlr,Adam19,Tnfaip2,Rgs1,Cdkn1a,Ebi3,Mmp9,Stat1,Socs3,Il13ra1,Cd200,Ier3,Pik3cd,Ifit3b,Isg20,Birc3,Tnfrsf1b,Rel,Ifit3,Il15,Ciita,Slamf7,Ddx60,Irs2,Nqo1,Cx3cr1,Ifit1bl1,Map3k6,Agrn,Msr1,Vcam1,Snn,Herc6,Rnf19b,H2-Ab1,Ptger4,Cdc42ep4,Map3k8,Cxcl10,Nr4a3,H2-Aa,Ifit1bl2,Plek,Cd86,Samsn1,Smg7,Hck,Pml,Usp18,Ddx58,Icam1,Isg15,Ifih1,Socs1,Sat1,Ifi44,Rab9,Ccng2,Dock10,Cst7,Bcl6,Tank,Gpsm2 |
| 2.074e-17 | -38.41 | positive regulation of lymphocyte activation | biological process | GO:0051251 | 259 | 60 | 20694 | 1406 |
Rasgrp1,Tnfsf4,Cdkn1a,Ccl2,Irf1,Myd88,Ikzf1,Nck1,Tlr9,Prdm1,Socs1,Ap3b1,Stat5a,Bst1,H2-Aa,Syk,Il12b,Ccdc88b,Mmp14,Cd74,Malt1,Bcl6,Ccl5,Il15,Irs2,Nod2,Nfkbid,Vcam1,Cd40,Cd86,H2-Ab1,Egr3,Peli1,Tnfsf9,Icosl,Cd38,Hsph1,Spn,Hlx,Ripk2,Il2rg,Il6,Cd80,Il1b,Pik3r6,Cd83,Cd274,Nlrp3,Lgals9,Il15ra,Axl,Itgal,Il18,Tnfsf14,Clcf1,Tnfrsf14,Cav1,Il4ra,Il12rb1,Nfkbiz |
| 2.242e-17 | -38.34 | GO_LEUKOCYTE_DIFFERENTIATION | MSigDB lists | GO_LEUKOCYTE_DIFFERENTIATION | 284 | 69 | 15632 | 1249 |
Ifna5,Ifnb1,Irf4,Ikzf1,Il6,Jun,Ptpn2,Spn,Syk,Ifi207,Il15,Ifna1,Clec4e,Ifi214,Fas,Egr1,Sirt1,Ifi203,Pou2f2,Ifi211,Csf1,Il10,Casp8,Mndal,Atm,Notch2,Clcf1,Fam20c,Ifi204,Irf1,Sema4a,Azi2,Pik3cd,Lyn,Mmp9,Rsad2,Tnfsf8,Batf2,Pde1b,Ifi205,Bcl6,Ifi209,Ifi213,Axl,Tnf,Src,Klf6,Ripk3,Relb,Ifna2,Batf,Cd74,Jmjd6,Malt1,Hhex,Itga4,Rhoh,Csf3,Ifna6,Ifi208,Cd86,Fzd5,Junb,Snx10,Vcam1,Plcl2,Clec4d,Il12b,Ptger4 |
| 2.329e-17 | -38.30 | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | 181 | 53 | 15632 | 1249 |
Ddx60,Evl,Pgs1,Sdc1,Samhd1,Sod2,Msr1,Myc,Mmp14,Chst11,Scarf1,Dram1,Max,Azi2,Jak2,Nfil3,Rnf31,Plscr1,Eef1e1,Etv6,Zfp281,Arg2,Batf,Rnf34,Pbx1,Sla,Ahsa1,Cd38,Hsph1,Casp1,Insl6,Gypc,Csf3r,Hspa1a,Tbc1d1,Gpr84,Dennd1b,Dock10,B3gnt5,Larp1,Serpinb9,Cmklr1,Osbpl3,Prkx,Serpinb2,Thbs1,Il15ra,Trafd1,Rgl1,Gch1,Flrt2,Gpr132,Il12rb1 |
| 2.329e-17 | -38.30 | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_DN | 181 | 53 | 15632 | 1249 |
Samhd1,Vcan,Fos,Ifit1bl1,Bcl2a1b,Ccl12,Fscn1,Orai2,Ccl4,Adam19,Acsl1,Hmgcs1,Endod1,Max,Oasl1,Tdrd7,Trim14,St3gal5,Alas1,Htra1,Itgal,S100a8,Cd38,Myd88,Crlf3,Cd14,Stat2,Isg15,Aim2,Sele,Bcl2a1d,Psma6,Gsr,Ifi44,Pnp2,Ifit2,Casp1,Glrx,Bcl2a1a,Ikbke,Tnfsf10,Serpinb9,Uba7,Oas2,Ube2l6,Tlr1,Lcp2,Irf7,Fubp1,Ifit1bl2,Plek,Slc31a2,Gch1 |
| 2.329e-17 | -38.30 | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP | 181 | 53 | 15632 | 1249 |
Ly75,Psma6,Nfkbie,N4bp1,Cst7,Ehd1,Cd83,Tnfaip3,Hlx,Marcksl1,Isg15,Traf1,Sell,Ddit4,Spint2,Inhba,Ccl5,Rgl1,Cdyl,Txn1,Slc31a2,Nampt,Irf7,Dusp5,Kdm6b,Rnf19b,Il2rg,Ak4,Kcna3,Gadd45g,Optn,Sod2,Gadd45b,Dock4,Ets2,Trip10,Rnd3,Angpt1,Olr1,Gbe1,Aldh1b1,Etv6,Nfkb1,P4ha1,Eno2,Birc3,Gem,Tnip1,Fscn1,Cflar,Mmp9,Filip1l,Ier3 |
| 2.456e-17 | -38.25 | GO_REGULATION_OF_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_CELL_PROLIFERATION | 1365 | 197 | 15632 | 1249 |
Pdgfrb,Osm,Map2k1,Cd274,Fzd5,Gja1,H2-Eb1,Bst1,Icosl,Nr4a3,Il18,Ripk2,Hmox1,Ptges,Htr2b,Il1b,Gcnt2,Kitl,Cxcl1,Stat5a,Mecp2,Stat3,Sat1,Fabp3,Prdm1,Ccl3,Cd38,Pdgfc,Ccdc88b,Pbx1,Sav1,Nos2,Pid1,Cav1,Ednrb,Tnfrsf1b,Egln3,Rictor,Zeb1,Ifit3b,Odc1,Pim2,Ptgir,Egr3,Notch2,Ptpn2,Hmga1,Itgav,Morc3,Ift57,S1pr2,Pla2g4a,Cx3cl1,Kat2b,Cdkn2d,Fas,Ahr,Tspo,Cd80,Il27,Nampt,Jarid2,Csf3,Pdgfb,Cxcl10,Ptafr,Dnaja2,Ptger4,Pf4,Vegfc,Bambi,Thbs1,Birc2,Cd40,Src,Ccnd1,Kdm5b,Mdm2,Pnp2,Casp3,Il1a,Hif1a,Calcrl,Lif,Marcksl1,Hlx,Hck,Notch1,Cd164,Tnfrsf8,Ptch1,Ifit3,Eef1e1,Sirt1,Jag1,Htra1,Adrb2,Stat1,Nox1,Cflar,Clcf1,Flt1,Chst11,Nod2,Edn1,Egr1,Atf3,Angpt1,Tnfrsf14,Htr2a,Ppp1r15a,Ccl5,Cxcl2,Inhba,Il12rb1,Sh3bp4,Rapgef2,Nrp2,Crkl,Vcam1,Bcl6,H2-Q6,Tnf,Errfi1,Hdac1,Tnc,Cd74,Rnf139,Nupr1,Parp10,Tnfaip3,Etv5,Sgk3,Atm,Fabp7,Csf1,Lyn,Trib1,Ptk2,Cdkn1a,Jak2,Syk,Sod2,Eif2ak2,Nr4a1,Plac8,Spn,Pde5a,Irs2,Col18a1,Nck1,Il15,Trp53i11,Cd86,Junb,Tyk2,Wars,Btg2,Il12b,Ptgs2,Cd55,Ptprj,Timp1,Acvrl1,Fgr,Intu,Sphk1,Pml,H2-Q7,Hhex,Ripk3,Bmp2,Il10,Dach1,Timeless,Mafg,Irf1,Tnfsf4,Ebi3,Igf1r,Hcls1,Kdr,Jun,Ccl12,Nfkbia,H2-Q4,Cx3cr1,Myc,Peli1,Il6,Ccr3,Spry2,Il4ra,Etv3,Phip,Prnp,Plau |
| 2.461e-17 | -38.24 | nucleus | cellular component | GO:0005634 | 6691 | 600 | 20747 | 1409 |
Dtx2,Vps54,Atm,Gk,Mtus1,Kmt5a,Prdx1,Gdf15,Samsn1,Asf1a,Hmgn3,Ikbkg,Phf11c,Mefv,Rgcc,Irf8,Bcorl1,Maml2,Ifi204,Abtb2,Tcf4,Upp1,Parp11,Slc16a3,Plekha5,Dcp1a,Jmjd6,Dyrk2,Dync1h1,Spn,Keap1,Mark2,Src,Zfp800,Sh3bgrl2,Stap1,Noct,Eya4,Pde4b,Nlrp3,Bnip3,Cdyl2,Dnaja1,Junb,Fignl2,Syne2,Klf8,Sirt1,Ifi214,Rapgef5,Il15,Mdn1,Cx3cr1,Fam111a,Psmb6,Clic4,Wdr43,Dnase1l3,Chmp4b,Trib3,Cnp,Mpp7,Dcp2,Tle3,Spry2,Phlda1,Slfn1,Cdk5r1,Csrnp1,Oas2,Casp3,Ptpn2,Dr1,Filip1l,Grk3,Wars,Rcl1,Prag1,Rnf14,Sp140,Ciapin1,Usb1,Txn1,Higd1a,Ifi207,Gadd45g,Mndal,Myc,Cebpd,Arid5a,Tnks1bp1,Igf2bp2,Mov10,Sema4a,Gadd45b,Il15ra,Myd88,Taf4b,Nfil3,Eef1e1,Fam53c,Itpr1,Ppp4r2,Mecp2,Peli1,Egr3,Ifi209,Cep350,Rgs3,Dst,Cycs,Rnf34,Crkl,Cd38,Hlx,Snx10,Zyx,Ogfr,Irak3,Ppp2r5a,Trim26,Zfp945,Hdac1,Nr1h3,Tyk2,9130023H24Rik,Errfi1,Phf6,Tulp3,Itgav,Smg7,Mx2,Tet2,Ccnj,Map2k4,Crbn,Pdk3,Trip13,Prpf4,Casz1,Slfn5,Mafg,Ier3,Asap3,Dmwd,Cutc,Nfkbiz,Maff,Nr3c1,Aftph,Chd9,Rsad2,Slc44a1,Dock4,Nfkbia,Lnpk,Ago3,Tut7,Rbbp8,Mfap3l,Kat2b,Csrp1,Etv6,Stat3,Dck,Tgs1,Mcmbp,Plk2,Ikbke,Rbms2,Rfx5,Nck1,Hmga1,Ezr,Eif2ak2,Tiparp,Prnp,Vezt,Spire1,Plekhg1,Nfxl1,Prdm1,Casp8,Mdfic,Actb,Trmt1l,Psme2,Bcl9,Irak2,Ccne1,Plac8,Tmem176b,Kdm4a,Zfp513,Sinhcaf,Dusp8,Rhoc,Pbx1,Dnaja2,Cgas,Gja1,Hmga2,Mppe1,Oas3,Pfkfb3,H3f3b,Slc30a1,Pnpt1,Pou3f1,Lap3,Btg2,Oas1a,Arl4a,Birc2,Bcl6,Smc5,Oas1g,Hat1,Hopx,Cacybp,Tor3a,Slfn9,Ifi213,Psme1,Perm1,Dock10,Dusp2,Socs1,Carmil1,Foxp4,Rabgef1,Rsbn1,Anp32a,Isg20,Ncoa7,Kdr,Plekha2,Ncoa5,Dusp16,Zhx2,Morc3,Lhx2,Crlf3,Ralgds,Herc6,Mmp14,Cnot4,Med21,Nek6,Ptch1,Nfkbie,Isg15,Spred1,Daxx,Lyn,Pla2g4a,Trim30a,Stat4,Apba1,Hmox1,Stx6,Phf11d,Stat1,Gpc1,Timeless,Mt1,Adar,Prdx5,Tent4a,Prpf38a,Uaca,Plagl1,Gem,Spen,Rbpms,Adrb2,Katna1,Prkx,Mier3,Sesn3,Wdfy1,Rars,Flt1,Zbtb5,Syk,Mycl,Hsph1,Tab2,Plagl2,Gch1,Top3a,Tbc1d1,Igf1r,Tma16,Zfp40,Rrs1,Hspa2,Prkce,Egr2,Sap30,Tnfrsf1b,Sp110,Gbp3,Znfx1,Txnrd1,Jak2,Egln3,Ciita,Nxf1,Dtx3l,Egr1,Nmral1,Snapc1,Brwd3,Rbms1,Nr4a1,Stk40,Kdm6b,Phf11b,Stip1,Dusp1,Ikzf1,Parp12,Sp100,Ctsc,AA467197,Mx1,Phf11a,Etv5,Ccdc86,Mafk,Cpd,Bcor,Oasl2,Irf1,Jun,Cyth3,Zeb1,Psmb9,Ankrd17,Lgals9,Klf2,Uba7,Cdyl,Etnk1,Noc4l,P4ha2,Cop1,Yju2,Ptges,Magohb,Casp2,Rbl1,Casp7,Clcn7,Agtrap,Pou2f2,Pdgfc,Swap70,Mvp,Kdm5b,Dse,Fos,Sh3bp4,Resf1,Batf,Pml,Tasor2,Lox,Dusp5,Mapkapk2,Osbpl3,Klf6,Brd2,Phlpp2,Aim2,Fabp7,Trib1,Nmi,Tra2a,Arid5b,Irf7,Ddx4,Gsdmd,Tfec,Klf3,Fas,Cited2,Xaf1,Ubash3b,Rap1gap2,Rai14,Psmb10,Sbds,Dnajb4,Nampt,Irf4,Irf2,Hap1,Pcgf5,Cenpj,Samhd1,Fubp1,Nsd3,Jdp2,Cept1,Psmb8,Hspa1b,Plk3,Ube2e1,Rab3ip,Ccng2,Flnb,Parp3,Tal2,Alas1,Nfkbid,Fosb,Zc3hav1,Cdkn1a,Aff1,Socs7,Apaf1,Sde2,Kpna3,Psip1,Etv3,Spata13,Hhex,Mcm9,Optn,Rmdn3,Pik3r5,Atf3,Gfi1,Pdgfrb,Ier2,Tpx2,Jarid2,Zc3h12a,Ubr4,Acsl5,Oas1b,Parp14,Bbx,Sik3,Casp1,Zfp281,Myo10,Map2k1,Mt2,4932438A13Rik,Psma6,Ep400,Ascc3,Nfkbil1,Serpina3g,Ccnd1,Zup1,Relb,Ccnd2,Sertad3,Ifi205,Armc8,Helz2,Hcls1,Med13,Cdkn2d,Oasl1,Pkp4,Hspa1a,Palld,Hilpda,Cenpe,Dek,Rnf114,Smox,Dpy19l1,Ass1,Dennd1b,Tent2,Hif1a,Setdb2,Uchl1,Pttg1,Plscr1,Hivep3,Ell2,Themis2,Notch1,Rpgrip1l,Zfp319,Serpinb6b,Phip,Akt3,Trim21,Glrx,Parp10,Stxbp1,Cpeb4,Dusp14,Tap2,Mapkbp1,Ifi35,Tlk2,Clic5,Mxd1,Iigp1,Ifi211,Batf2,Ifrd1,Pdlim7,Vrk2,Sqstm1,Parp9,Ahr,Ifi208,Serpinb9,Cers6,Zfp36,Ifi203,Tcea1,Gbp2,Trip10,Usp25,Nos2,Dnajb2,Tnip1,Slc9a1,Ptger4,Ptgs2,Notch2,Ahrr,Aebp2,Tor1aip2,Mcm6,Aldh1b1,Birc3,Slc2a1,Ednrb,Max,Ets2,Sphk1,Golga3,Ifih1,Marcks,Hivep2,Prdm9,Dusp4,Cacna1d,Hinfp,Polr2g,Htr2b,Nfkb2,Ptk2,Tor1aip1,Pnp2,Mamld1,Malt1,Psmd10,Mtdh,Apobec3,Dach1,Adam19,Rcan1,Usp18,Nupr1,Nfkb1,Usp31,Nlrc5,Phlpp1,Ranbp2,Zmynd15,4930453N24Rik,Stat2,Stat5a,Pim1,Olr1,Shfl,Itpkc,Spic,Rel,Arid4a,N4bp1,Rgs14,Hck,Nfkbib,Mdm2,Zbp1,Riox2,Mcm10,Rilpl1,Usp12,Nr4a3,Sav1,Lipe,Klf7,Tshz1,Tnfaip3,Triobp |
| 2.563e-17 | -38.20 | regulation of T cell activation | biological process | GO:0050863 | 306 | 66 | 20694 | 1406 |
Il1b,Pik3r6,Nlrp3,Cd274,Cd83,Lgals9,Tnfrsf1b,Zc3h12a,Itgal,Fgl2,Il18,Tnfsf14,Ripk3,Tnfrsf14,Cav1,Tarm1,Il4ra,Il12rb1,Casp3,Nfkbiz,Cd86,Tnfsf9,Prnp,Peli1,Egr3,H2-Ab1,Icosl,Hsph1,Spn,Hlx,Ripk2,Il2rg,Arg2,Il6,Cd80,Zeb1,Cgas,Il12b,Ccdc88b,Cd74,Ctla2a,Ptpn2,Malt1,Pde5a,Bcl6,Ccl5,Il15,Nfkbid,Ifnb1,Vcam1,Rasgrp1,Sdc4,Tnfsf4,Ikzf1,Ccl2,Irf1,Nck1,Il27,Prdm1,Socs1,Ap3b1,Adora2a,Slfn1,Stat5a,H2-Aa,Syk |
| 2.665e-17 | -38.16 | ion binding | molecular function | GO:0043167 | 5422 | 514 | 20217 | 1400 |
Phf11a,Hk1,Dync1h1,Prnp,Jak2,Gbp8,Ppa1,Mthfr,Nkiras1,Dtx3l,Fabp7,Dhx58,Lmo4,Snx2,Acsl1,Sele,Kif3c,Kcnj2,Ago3,Hivep2,Cdkn1a,Psd,Gpc1,Mapkapk2,Fcho2,Adar,Pdgfrb,Ripk3,Cpd,Mob3c,Rab20,Itga9,Eif2ak2,Stat5a,Rhoq,Itpkc,Endod1,P4ha2,Gng12,Pml,Rab21,Hinfp,Cutc,Traf2,Apaf1,Prrg4,Gclc,Wars,Pim3,Kdm4a,Mitd1,Rsad2,Pde3b,Zfp319,Prdm9,Tab2,Dst,Nox1,Lipg,Srxn1,Ppm1k,Ube2f,Trafd1,Rhof,Crbn,Nos2,Rasgrp1,Noct,Tor3a,Lpcat2,Klf6,Rhoc,Arhgap26,Pdk3,Aoah,Nr3c1,Pim1,Rubcnl,Gmppb,Ddx58,Tuba4a,Stk40,Smc5,Zyx,Clec4e,Itgav,Col11a2,Pf4,Plekhn1,Cyth3,Ascc3,Cpeb4,Clec4n,Sat1,Dennd1b,Ranbp2,Il1a,Trim56,Hspa1b,Vrk2,Ccl7,Tap1,Mob3b,Gbp2,Dtx2,Bcl6,Acp5,Slc25a25,Rhoh,Gbp3,Ift22,Mocs1,Ptch1,Inpp5b,Rabgef1,Axl,Gbgt1,Inpp1,Riox2,Plekha4,Dck,Rcn1,Tgtp1,Dcp2,Itga5,Mdm2,Asah2,Gsdmd,Trim36,Hsph1,Pde1b,Prdm1,Atm,Sell,Adap2,Lrp4,Trim13,Acvr1b,Hdc,Mx1,Adhfe1,Gpd2,Rras2,Rap2c,F10,Yju2,Zc3hav1,Zswim4,Zcchc2,Cop1,Lcn2,Mid1,Slfn8,Fam20c,Hmox1,Cp,Ksr1,Ikzf1,Sap30,Mmp14,Irgm1,Dyrk2,Ptk2,Ext1,Gca,Atp2b4,Notch2,Trim26,Nr1h3,Atp13a1,Dgka,Katna1,Cd34,Ddx4,Pla2g7,Nod2,Lyn,Prkce,Arl5b,Ptafr,Ampd3,Htr2a,Adprm,Mcm10,Clec4d,Snn,Hspa1a,Hk3,Egr1,Hk2,Mgat1,Ccl5,Nt5c3,Adam19,Klf3,Egr3,Klf7,Parp12,Traf1,Ctsc,Lacc1,Prag1,Ankib1,Slfn5,Pgk1,Plod3,Myo1b,Tiparp,Eya4,Birc3,Ehd1,Txnrd1,Abcc5,Mthfd1l,Znrf1,Enpp4,Irak3,Sec24a,Ak4,Gtpbp2,Smpdl3b,Tlk2,Acpp,Trib3,Dtnb,Znrf3,Kdr,Atp10a,Oas2,Lnpep,Clcn5,Sqstm1,Myo10,Nsd3,Nr4a3,Mefv,Zc3h12c,Fgr,Pgs1,Pgm1,Casz1,Cd300lf,Gfpt1,Arl4a,Asns,Trim14,Rars,Ikbkg,Map2k4,Met,Mcm9,Itgal,Parp9,Tap2,Xaf1,Tent2,Hck,Mt2,Cdk5r1,Top3a,Gna15,Mark2,Kif9,Eno2,Gem,Cd69,Vcan,Rhou,Pim2,Timp1,Layn,Prkx,Acsl5,Mov10,Jmjd6,Siglece,Ciapin1,Tank,Syk,Lox,Mcm6,Plcl2,Plek,Ifih1,Ptgs2,Gbp7,Zmynd15,Zc3h12a,Cmpk2,Tulp3,Phf11d,Zhx2,Tet2,Grk3,Trib1,Plscr1,Tent4a,Gch1,Arg2,Pde4b,Ep400,Ptges,Htr2b,Oasl1,B4galt4,Phyh,Pla2g4a,Adrb2,Abcc1,Pdss1,Lnpk,Egln3,Ube2e2,Gda,Actb,Hivep3,Rab32,Cnot4,Klf2,Car13,Extl2,Slfn9,Sco1,Notch1,Asap3,Papss2,Trim21,Pde5a,Foxp4,Rab9,Fabp3,Tshz1,Parp14,Zfp281,Ddhd1,Reps1,Rab10,Samhd1,Map4k4,Nlrp3,Klf8,Sphk1,Agrn,Phf6,Zfp36,Flt1,Fchsd2,Ltbp2,Setdb2,Ldlr,Irak2,Lhx2,Plekha5,Oasl2,Rnf34,Acvr1,Akt3,Ube2e1,Scyl2,Pcgf5,Prkar2b,Idi1,Trmt1l,S100a8,Ass1,Mmp9,Kmo,Nod1,Helz2,Cox17,Itga4,Rapgef2,Etnk1,Rnf139,Phlpp1,Zfp513,Plekhf2,Ccl8,Rnf14,Kdm5b,Ccl2,Slc25a12,Gbp9,Gbp2b,Col27a1,Plod2,Swap70,Pik3cd,Plekha2,Rnf145,Hsd17b12,Mmp25,Sesn3,Iigp1,Zfp800,Antxr1,Irgq,Sgk3,Usp12,Leng9,Trim34a,Kdm6b,P2ry2,Igf1r,Gk,Arl5c,Rnf135,Itpr1,Zbtb5,Hspa2,Src,C1ra,Hcar2,Trim12a,Gfi1,Oas3,Sod2,Sec24b,Cenpe,Lpar1,Rnf31,Pikfyve,Rac3,Gbe1,Mmp13,Mppe1,Aida,Egr2,Plk2,Dnaja2,Sik3,Gsr,Nr4a1,Sirt1,Nlrc5,Tax1bp1,Trip13,Mt1,Chd9,Morc3,Abcb1a,Nrp2,Tpm4,Atp11a,Lrp8,Rnf19b,Optn,Me1,Rnf114,Rsbn1,Alas1,Pnp2,Znfx1,Apobec3,Apba1,Thbs1,Ch25h,Map2k1,Tcea1,Rnd3,Map3k8,Jag1,Dnaja1,Csrp1,Cacna1d,Mlkl,Pcx,Nek6,Pfkl,Cemip2,Cept1,Acvrl1,Wdfy1,Adgre4,Ikbke,Micall2,P4ha1,Cxcl10,Map3k6,Rnf24,Plk3,Stard5,Rnd1,Nlrc4,Pdlim7,Zup1,Ciita,Mul1,Ube2l6,Col18a1,Pde7b,Birc2,Ubr4,Tnfsf10,Tnfaip3,Rab19,Tut7,Isg20,Rnf19a,Arf4,Lap3,Snx10,Phlpp2,Ppm1l,Aebp2,Tyk2,Mthfd2,Ripk2,Zeb1,Rffl,Traf5,Trim30a,Cgas,Clcn7 |
| 2.686e-17 | -38.16 | LIANG_SILENCED_BY_METHYLATION_2 | MSigDB lists | LIANG_SILENCED_BY_METHYLATION_2 | 46 | 26 | 15632 | 1249 |
Slpi,Xaf1,Oas2,Inhba,Oas1a,Ccl5,Ifit1bl2,Lcn2,Irf7,Ifit3,Tnfsf10,Serpinb2,Cxcl1,Stat1,Oas1g,Uchl1,C3,Ifit3b,Ptgs2,Il6,Ifi44,Sod2,Ifit1bl1,Ifit2,Tnfaip3,Icam1 |
| 2.793e-17 | -38.12 | negative regulation of leukocyte activation | biological process | GO:0002695 | 182 | 49 | 20694 | 1406 |
Bcl6,Pde5a,Samsn1,Ptpn2,Cd74,Parp3,Cst7,Nr1h3,Ifnb1,Nfkbid,Fas,Rabgef1,Prdm1,Milr1,Irf1,Il10,Fcgr2b,Sdc4,Tnfsf4,H2-Aa,Adora2a,Slfn1,Socs1,Cx3cl1,Cd300lf,Fgl2,Zc3h12a,Axl,Lgals9,Cd274,Casp3,Tarm1,Il4ra,Lyn,Tnfrsf14,Tnfaip3,Hmox1,Cd200,Spn,Prnp,Peli1,H2-Ab1,Cd86,Ldlr,Cd80,Atm,Arg2,Abr,Hlx |
| 2.804e-17 | -38.11 | GSE6269_FLU_VS_E_COLI_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_E_COLI_INF_PBMC_UP | 158 | 49 | 15632 | 1249 |
Smg7,Isg15,Usp18,Cd74,H2-Q7,Rsad2,Atp13a1,Ifi44,Ifi209,Oas3,Ifi205,H2-Q6,N4bp1,Ifi213,Gtpbp2,Oas1g,Herc6,Larp1,Uba7,Parp12,Tyk2,Oas2,Ifi208,Irf7,Brd2,Ifi207,Mark2,Adar,Zbp1,Ifi214,Ddx60,Zyx,Agrn,H2-Q4,Eif2ak2,Actb,Ifi204,Mmp9,Oasl1,Mtdh,Ifi35,Pou2f2,Xaf1,Ifi203,Oas1a,Trim21,Trim14,Ifi211,Mndal |
| 2.975e-17 | -38.05 | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_UP | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_UP | 188 | 54 | 15632 | 1249 |
Cish,Rnf24,Gbp4,Gbp9,Tbc1d1,Nfkbie,Zfp800,Mdm2,Clmp,Slc25a37,Relb,Mcoln2,Ch25h,Cd74,Slc2a6,Antxr1,Tlr1,Phlda1,Sap30,Adora2a,Cxcl2,Nfkbid,Csf3,Tshz1,Med21,Osm,Clic4,Nfkb2,Il1rn,Snn,Herc6,Il12b,Map3k8,Adora2b,Chic2,Lrch1,Tor1aip2,4932438A13Rik,Clec4e,Il15,Tap1,Enpp4,Col18a1,Nck1,Flnb,Csf1,Hivep3,Jdp2,Nfkb1,Hdc,Gbp7,Clcn7,Cdkn1a,Map2k4 |
| 3.078e-17 | -38.02 | positive regulation of kinase activity | biological process | GO:0033674 | 517 | 91 | 20694 | 1406 |
Map2k4,Fcgr1,Adrb2,Tlr9,Eif2ak2,Map3k8,Cenpe,Atp2b4,Ptk2,Pdgfrb,Fzd5,Pde5a,Gadd45g,Htr2a,Csf1,Lrp8,Spry2,Nod2,Mtcp1,Edn1,Stap1,Map2k1,Fpr2,Src,Map4k4,Tab2,Mul1,Ripk2,Lpar1,Irgm2,Tnfsf15,Traf2,Flt1,Nek6,Pdgfb,Ranbp2,Il18,Irak2,Pim1,Ripk3,Jak2,Tlr6,Crkl,Rasgrp1,Sdc4,Cdkn1a,Angpt1,Met,Pik3r5,Tnf,Mapkbp1,Mdfic,Daxx,Kitl,Tpx2,Syk,Agrn,Il12b,Il1rn,Tlr1,Gadd45b,Cd74,Malt1,Gdf15,Egr1,Rgcc,Fgr,Map3k6,Cd40,Bmp2,Prnp,Thbs1,Rapgef2,Hsph1,Mmd,Higd1a,Ccnd2,Acsl1,Il1b,Pik3r6,Lgals9,Pdgfc,Sirt1,Mlkl,Ccnd1,Cdk5r1,Psmd10,Lyn,Lmo4,Htr2b,Ikbkg |
| 3.410e-17 | -37.92 | regulation of interleukin-1 production | biological process | GO:0032652 | 91 | 34 | 20694 | 1406 |
Casp4,Hdac1,Casp8,Casp1,Pml,Cx3cr1,Ptger4,Arg2,Ripk2,Ifi204,Ccl3,Aim2,Cx3cl1,Ifi211,Acp5,Gsdmd,Fzd5,Malt1,Zc3h12a,Lgals9,Nlrp3,Mefv,Mndal,Sphk1,Ifi205,Errfi1,Ifnar1,Jak2,Nod1,Nod2,Tnfaip3,Hk1,Tlr2,Egr1 |
| 3.845e-17 | -37.80 | hemopoiesis | biological process | GO:0030097 | 656 | 106 | 20694 | 1406 |
Il6,Atm,Hif1a,Bcl2a1d,Cnn2,Cd34,Spn,Plscr1,Tnfsf9,Sema4a,Samd9l,Casp3,Relb,Lyn,Clcf1,Pbx1,Ahr,Plcl2,Fam20c,Sirt1,Ifna1,Fubp1,Tet2,Axl,Irf8,Hhex,Cited2,Syk,Kdr,Rsad2,Kitl,Sod2,Jun,Tnf,Ifna6,Angpt1,Ikzf1,Pml,Ccr1,Ciapin1,Casp8,Jmjd6,Ifnb1,Notch2,Egr1,Bcl6,Junb,Malt1,Cd74,Il12b,Ifna5,Ifna4,Heatr9,Tmod3,Batf2,Csf3,Stat3,Src,H2-Ab1,Clec5a,Snx10,Tnfsf8,Rrs1,Dock10,Ptprj,Hcls1,Tcea1,Jak2,Inhba,Tnfaip3,Ripk3,Clec4d,Tlr2,Adar,Gpr18,Clec4e,Pou2f2,Cd300lf,Tiparp,Gfi1,Rhoh,Herc6,Ptger4,Azi2,Arid4a,Ifna2,Apobec3,Stat5a,Slamf8,Batf,Irf1,Klf2,Tent2,Stap1,Fas,Il15,Csf1,Gadd45g,Cebpd,Pdgfrb,Irf4,Ptpn2,Fzd5,Ppp4r2,Prkx,Etv6 |
| 3.850e-17 | -37.80 | GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP | MSigDB lists | GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP | 189 | 54 | 15632 | 1249 |
Myadm,Ccr1,Osm,Cd274,Cd86,Tmeff1,Cxcl2,Hk2,Stx11,Dusp5,Ptger4,Pim1,Cxcl1,Tcf4,Arid5a,Cish,Egr2,D1Ertd622e,Fgl2,Mcoln2,Prdm1,Zfp281,Batf,Mdfic,Gbp2,Tnfrsf1b,Hdc,Gem,Gbp7,Casp4,Il10,Pstpip2,Cd69,Pim2,Ell2,Ptk2,Ier3,Trib1,Cd300lf,Sh3bgrl2,Nfil3,Pmepa1,Plac8,Jun,Tiparp,Fcgr2b,Phlpp1,Cdkn2d,Tmem176b,Dmxl2,Ccnd2,Ubash3b,Pfkfb3,Ahr |
| 3.850e-17 | -37.80 | GSE14769_20MIN_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_20MIN_VS_360MIN_LPS_BMDM_DN | 189 | 54 | 15632 | 1249 |
Aim2,Ch25h,Magohb,Arg2,Agtrap,Sell,Timp1,Ttc39c,Swap70,Itpr1,D1Ertd622e,Oaf,Slc31a1,Usp42,Lox,Kif3c,Zhx2,Tcea1,Sp110,Ccnj,Txn1,Brwd3,Flrt2,Sipa1l1,Rab10,H2-Aa,Maff,Dgka,Plagl1,Nr1h3,Sgcb,Gpc1,Lpcat2,Aff1,Ppfibp1,Rbl1,Crbn,Trim36,Ass1,Trmt1l,Tmem184b,Katna1,Ppfia3,Tnfsf4,Casp7,Cacna1d,Gfpt1,Orai2,Tmem219,Procr,Zeb1,Bcl9,Tifa,Ccdc25 |
| 3.953e-17 | -37.77 | GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_UP | MSigDB lists | GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_UP | 183 | 53 | 15632 | 1249 |
Fos,Mrpl52,Nr4a1,Bcl2l11,Bcl2a1b,Dusp2,Trim13,Etv3,Nkiras1,P2ry14,Gmppb,Cdk5r1,Nfkbiz,Atf3,Egr1,Palld,Atp11b,Slc25a25,Gem,Tnfrsf1b,Ppp1r15b,Cd69,Leng9,Zfp36,Trib1,Egr3,Filip1l,Ccl4,Dusp1,Bcl2a1d,Egr2,Traf1,Ier2,Malt1,Plk3,Csrnp1,Tnfaip3,Sla,Ppp1r15a,Samsn1,Fosb,Junb,Dusp6,Nfkbid,Maff,Arl5b,Phf6,Map3k8,Nr4a3,Kdm6b,Dusp5,Bcl2a1a,Bambi |
| 3.973e-17 | -37.76 | RASHI_NFKB1_TARGETS | MSigDB lists | RASHI_NFKB1_TARGETS | 17 | 16 | 15632 | 1249 |
Lcn2,Birc3,Nfkbia,Dusp6,Mdm2,Btg2,Csf1,Nfkbib,Irf1,Map3k8,Dusp16,Relb,Tnfaip3,Cxcl1,Nfkb2,Tnip1 |
| 3.996e-17 | -37.76 | negative regulation of cellular protein metabolic process | biological process | GO:0032269 | 1051 | 146 | 20694 | 1406 |
Trim21,Edn1,Serpinb2,Dusp16,Xrn1,Birc2,Prkar2b,Dnaja1,Serpine1,Spry2,Dnajb2,Ptpn2,Ctla2a,Zfp36,Svbp,Dtx3l,Irak3,Gadd45g,Nr1h3,Rnf34,Plekhn1,Socs3,Plpp3,Atp2b4,Mov10,Phactr4,Socs1,Serpina3g,Adora2a,Eif2ak2,Slfn1,Tspo,Irf1,Ppp1r14b,Hdac1,Phlpp1,Ddit4,Nr4a1,Ppp1r15b,Sco1,Plaur,Birc3,Il10,Mllt6,Parp14,Ezr,Bcor,Timp1,Prdx5,Errfi1,Spint2,Crkl,Adar,Tnfaip3,Trib1,Zc3h12a,Swap70,Rnf139,Il18,Serpinb9b,Pid1,Rgs14,Usp25,Spred1,Lif,Gbp4,Serpina3f,Serpinb6b,Mvp,Stat3,Src,Ptprj,Tlk2,Jarid2,Wars,Igf1r,Larp1,Rabgef1,Serpinb9,Pmepa1,Uchl1,Kat2b,Cdkn2d,Ednrb,Ppp1r15a,Actb,Samsn1,Aida,Dusp4,Gclc,Spred3,Gadd45b,Cst7,C3,Dusp6,Ric1,Ubash3b,Tnf,Jun,Rffl,Angpt1,Met,Nck1,Ago3,Caml,Parp10,Atf3,Cdkn1a,Pml,Casp3,Plat,Myadm,Tnfsf14,Psmd10,Prkce,Lyn,Cav1,Ncoa7,Tnip1,Sirt1,Mmp9,Btg2,Mdm2,Il1b,Isg15,Hhex,Trib3,Dusp1,Il6,Kdm4a,Slpi,Ptgs2,Dusp8,Cflar,Bcl2a1d,Prnp,Dusp5,Fam129a,Cdyl,Hspa1b,Thbs1,Hsph1,Fam72a,Cpeb4,N4bp1,Dusp2 |
| 4.407e-17 | -37.66 | myeloid leukocyte activation | biological process | GO:0002274 | 120 | 39 | 20694 | 1406 |
Tlr3,Tlr6,Jak2,Lcp2,Lyn,Notch2,Relb,Jmjd6,Ifnb1,Ccl5,Nr4a3,Il15,Prkce,Tlr2,Slc7a2,Dnase1l3,Fcgr4,Irf4,Il18,Rhoh,Tlr1,Syk,Jun,Cx3cl1,Batf2,Tnf,Milr1,Tlr9,Pilrb1,Tnfsf9,Batf,Cx3cr1,Fpr2,Casp1,Nampt,Rasgrp1,Stx11,Il18rap,Fcgr2b |
| 4.543e-17 | -37.63 | GO_RESPONSE_TO_NITROGEN_COMPOUND | MSigDB lists | GO_RESPONSE_TO_NITROGEN_COMPOUND | 808 | 135 | 15632 | 1249 |
Prkce,Peli1,Il6,Edn1,Sdc2,Nod2,Slc7a11,Ccl12,Agrn,Nfkbia,Ezr,Ifit1bl1,Jun,Fos,Htr2a,Pde3b,Gng11,Adar,Plau,Ifna1,Atp2b4,Egr1,Phip,Sirt1,Jag1,Ccne1,Casp4,P2ry2,Il10,Gna15,Socs7,Prkar2b,Igf1r,Socs3,Stat1,Tnfsf4,Adrb2,Pde1b,Egr2,Rhoq,Casp3,Ccnd1,Mdm2,Casp1,Dusp1,Src,Birc2,P2ry12,Psmb9,Timp1,Nod1,Notch1,Mthfr,Agtrap,Socs1,Sell,Sphk1,Hif1a,Icam1,Ddx58,Ifna6,Pdgfb,Btg2,Junb,Nampt,Ifit1bl2,Klf2,Gng12,Ldha,Ptger4,Ptafr,Ptgs2,Pla2g4a,Ifnb1,Ifna5,Ass1,Klf3,Nr4a1,Eif2ak2,Ptpn2,Tspo,Zc3hav1,Fas,Cdk5r1,Mul1,Irs2,Sdc1,Kat2b,Zeb1,Slc9a1,Nfkb1,Cav1,Gfpt1,Jak2,Cdkn1a,Ptk2,Max,Cpeb4,Hmgcs1,Lyn,Stat3,Errfi1,Klf6,Tnf,Stat5a,Homer1,Traf2,Gnb4,Tnfaip3,Irak3,Ifna2,Pdgfc,Fabp3,Stxbp3,Rab10,Fzd1,Rapgef2,Sh3bp4,Gja1,Ccl5,Pde4b,Fosb,Atp6v1d,Ppp1r15a,Asns,Vcam1,Il1b,Htr2b,Ppp2r2a,Ripk2,Gng4,Hmox1,Tlr3,Nr4a3,Trib3 |
| 4.563e-17 | -37.63 | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | 234 | 61 | 15632 | 1249 |
Fpr1,Ttc39b,Tgfbi,Hp,Tfec,Gca,Osbpl3,Vcam1,Ccl5,Plek,AA467197,Ifi208,Slco3a1,Upp1,Prdm1,Mdfic,Gda,Ifi209,Ifi205,P4ha2,Ifi213,Fgl2,Cp,Sema4a,Cacnb3,Ifi204,Mmp9,Ell2,Il13ra1,C3,Nfil3,Igf1r,Fscn1,Casp4,Mndal,Lcn2,Hdc,Itgal,S100a8,Il18rap,Tmem176a,Ifi203,Stat4,Plscr1,Slpi,Isg20,Ifi211,P2ry14,Ifi214,Rtp4,Sgms2,Ccnd2,Tmem176b,Ifi207,Clec4e,Gpc1,Zbp1,Rras2,Fos,Rab32,Igsf6 |
| 4.599e-17 | -37.62 | positive regulation of protein kinase activity | biological process | GO:0045860 | 476 | 86 | 20694 | 1406 |
Egr1,Lrp8,Csf1,Rgcc,Spry2,Mtcp1,Nod2,Edn1,Stap1,Map3k6,Cd40,Il1rn,Agrn,Il12b,Gadd45b,Tlr1,Cd74,Ptk2,Malt1,Fzd5,Pdgfrb,Pde5a,Gdf15,Gadd45g,Htr2a,Mapkbp1,Tnf,Eif2ak2,Daxx,Mdfic,Map3k8,Kitl,Cenpe,Tpx2,Syk,Atp2b4,Rasgrp1,Sdc4,Map2k4,Cdkn1a,Met,Angpt1,Fcgr1,Pik3r5,Tlr9,Adrb2,Pim1,Ccnd1,Cdk5r1,Psmd10,Ripk3,Jak2,Tlr6,Htr2b,Ikbkg,Crkl,Il1b,Pik3r6,Lgals9,Pdgfc,Sirt1,Il18,Mlkl,Irak2,Tab2,Mul1,Lpar1,Mmd,Ripk2,Tnfsf15,Irgm2,Flt1,Higd1a,Ccnd2,Traf2,Acsl1,Nek6,Pdgfb,Bmp2,Map2k1,Prnp,Src,Hsph1,Map4k4,Rapgef2,Thbs1 |
| 4.795e-17 | -37.58 | YANG_BCL3_TARGETS_UP | MSigDB lists | YANG_BCL3_TARGETS_UP | 337 | 76 | 15632 | 1249 |
Mov10,Ifit3,Psmb8,Pdk3,Ednrb,Rasgrp1,Acsl1,Fam111a,Ifit3b,Etnk1,Ifi35,Tnfsf4,Oasl1,Agpat4,Dnajb2,Eif2ak2,Nr4a1,Sod2,Rapgef5,Ccl12,Parp14,Ctsc,Edn1,Il6,Sdc1,Pgm1,Ccnd2,Pttg1,Rtp4,Ddx60,Olr1,Tap1,Vps54,Serpine1,Ascc3,Irf7,Slc7a8,Gch1,Mmp13,Uba7,Ube2l6,Nmi,Tgfbi,Phyh,Nr4a3,Cxcl10,Hp,Herc6,Cd55,Cmpk2,Sp110,Glrx,Serpinb2,Plat,Psmb9,Timp1,Tnf,Lipe,Ifit2,Clmp,Fgl2,Dhx58,Rsad2,C1ra,Cp,Usp18,Calcrl,Stat2,Dtx3l,Gbp3,Trim12c,Fabp3,Ch25h,Gbp2,Sgk3,Gnb4 |
| 5.065e-17 | -37.52 | negative regulation of protein metabolic process | biological process | GO:0051248 | 1116 | 152 | 20694 | 1406 |
Plekhn1,Rnf34,Socs3,Plpp3,Phactr4,Mov10,Atp2b4,Serpina3g,Socs1,Slfn1,Adora2a,Eif2ak2,Tspo,Ppp1r14b,Irf1,Hdac1,Phlpp1,Plaur,Ppp1r15b,Nr4a1,Ddit4,Sco1,Birc3,Ezr,Parp14,Mllt6,Il10,Edn1,Serpinb2,Trim21,Xrn1,Birc2,Dusp16,Dnaja1,Prkar2b,Spry2,Serpine1,Dnajb2,Ptpn2,Ctla2a,Zfp36,Dtx3l,Irak3,Svbp,Gadd45g,Nr1h3,Usp25,Lif,Spred1,Serpina3f,Nos2,Gbp4,Mvp,Serpinb6b,Src,Stat3,Tlk2,Nmi,Ldlr,Ptprj,Hap1,Jarid2,Prdx5,Bcor,Timp1,Spint2,Errfi1,Crkl,Adar,Tnfaip3,Trib1,Swap70,Zc3h12a,Rnf139,Il18,Serpinb9b,Pid1,Rgs14,Dusp6,Ric1,Ubash3b,Tnf,Jun,Rffl,Met,Angpt1,Nck1,Caml,Ago3,Parp10,Cdkn1a,Atf3,Pml,Wars,Igf1r,Larp1,Rabgef1,Serpinb9,Pmepa1,Uchl1,Cdkn2d,Kat2b,Ppp1r15a,Samsn1,Actb,Ednrb,Dusp4,Aida,Spred3,Gadd45b,Gclc,Cst7,C3,Dusp1,Il6,Slpi,Kdm4a,Dusp8,Ptgs2,Cflar,Bcl2a1d,Prnp,Hspa1b,Cdyl,Dusp5,Fam129a,Fam72a,Hsph1,Cpeb4,Thbs1,N4bp1,Dusp2,Casp3,Itgav,Plat,Myadm,Tnfsf14,Psmd10,Prkce,Lyn,Cav1,Nfkb1,Tnip1,Ncoa7,Mmp9,Sirt1,Mdm2,Btg2,Il1b,Hhex,Isg15,Trib3 |
| 5.132e-17 | -37.51 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_UP | 184 | 53 | 15632 | 1249 |
Arhgef3,Ogfrl1,Errfi1,Egr2,Icam1,Mapkbp1,Med21,Samsn1,Cd274,Brd2,Plek,Junb,Maff,Inhba,Mmp13,Fpr1,Osgin2,Adora2b,Pim1,Ptger4,Serpinb2,Cxcl1,Jun,Nfkbia,Dtnb,Ccl2,Il6,Il4i1,Mmp14,Igsf6,Parp14,Arl4a,Phip,Nck1,Nfkbiz,Atf3,Olr1,Dusp14,Slamf7,Pim3,Slc25a25,Casp4,Gem,Irf8,Birc3,Met,Rnf19a,St3gal5,Zfp36,Srxn1,Rab20,Dusp16,Tnip1 |
| 5.132e-17 | -37.51 | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_DN | 184 | 53 | 15632 | 1249 |
Hmox1,Slc31a1,Chic2,Il18,Map3k8,Il1rn,Pkp4,Glrx,Pde4b,Nampt,Ccl5,Tshz1,Brd2,Plk2,Reps1,Hk2,Fabp3,Cd14,Cd38,Mdfic,Gbp2,Klhl25,Ttc39c,Slc39a4,Mtdh,Denr,Cd200,Mafg,Fscn1,Znrf1,Cd82,Esd,Frmd6,Birc3,Lmo4,Srxn1,Flnb,Tdrd7,Atf3,Palld,Gbe1,Clec4e,Zbp1,Olr1,Me1,Map3k6,Rab32,Sod2,Trmt1l,Gclm,Fcgr2b,Mmp14,Cpd |
| 5.132e-17 | -37.51 | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 184 | 53 | 15632 | 1249 |
Sipa1l1,Map2k1,Samsn1,Pde4b,Maff,G3bp2,Pdlim7,Slc43a3,Dnaja2,Zhx2,Snn,Plaur,Snapc1,Bcl2a1a,Eno1,Serp1,Slc16a3,Tnf,Psma6,Bcl2a1d,B3gnt5,Nfkbie,Gpr84,Sphk1,Icam1,Cd83,Gna15,Nfkb1,P4ha1,Stx6,Stat4,Ier3,Ell2,Cdkn1a,Fam162a,Dock4,Tiparp,Hmga1,Sod2,Bcl2a1b,Pik3r5,Sqstm1,Ppp1r14b,Nfkbia,Gadd45g,Aftph,Dusp2,Il4ra,Etv3,Mapkapk2,Olr1,Chmp4b,Fbrsl1 |
| 5.537e-17 | -37.43 | LINDGREN_BLADDER_CANCER_CLUSTER_2B | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2B | 345 | 77 | 15632 | 1249 |
Bcl2a1b,Ccl12,Gadd45b,Nfkbia,Nr4a1,Jun,Pdpn,Ccl2,Peli1,Fcgr2b,Col18a1,Egr1,Nek6,Palld,Nfkbiz,Gng11,Rnd3,Samhd1,Aff1,Birc3,Gem,Cav1,Itgal,Isg20,Cnn3,Socs3,Filip1l,Pim2,Ebi3,Hmgcs1,Ptk2,Pik3cd,Adam19,Nfil3,Lrrc8c,Cst7,Tpst1,Cd302,Tcf4,Tnc,C1ra,Bcl2a1d,Fgl2,Sele,Nfkbie,Glipr2,Rhoh,Hhex,Itga4,Ier2,Ch25h,Malt1,Traf1,Sell,Icam1,Il1a,Tnfaip3,Csrp1,Myadm,H2-Eb1,Rgl1,Slc7a2,Pdgfrb,Lcp2,Samsn1,Nrp2,Adora2a,Dusp5,H2-Ab1,Il2rg,Slc43a3,Mob3b,Clic4,Pcdh7,Bcl2a1a,Vcam1,Plaur |
| 5.919e-17 | -37.37 | regulation of response to cytokine stimulus | biological process | GO:0060759 | 115 | 38 | 20694 | 1406 |
Irf7,Cav1,Tlr2,Csf1,Ccl5,Ddx58,Adar,Rabgef1,Ifih1,Vrk2,Sphk1,Zbp1,Stap1,Axl,Gfi1,Cd74,Il1rn,Irak2,Cd300lf,Irak3,Ptpn2,Irgm2,Mul1,Parp9,Ripk2,Rffl,Ikbke,Socs1,Syk,Il6,Nlrc5,Traf2,Casp1,Parp14,Samhd1,Casp4,Angpt1,Irgm1 |
| 6.199e-17 | -37.32 | positive regulation of transferase activity | biological process | GO:0051347 | 586 | 98 | 20694 | 1406 |
Map2k4,Fcgr1,Tlr9,Arrdc4,Adrb2,Eif2ak2,Map3k8,Cenpe,Atp2b4,Dcun1d3,Ptk2,Pdgfrb,Fzd5,Pde5a,Myc,Dtx3l,Gadd45g,Htr2a,Csf1,Lrp8,Spry2,Nod2,Mtcp1,Stap1,Edn1,Map2k1,Fpr2,Src,Map4k4,Tab2,Lpar1,Mul1,Ripk2,Irgm2,Tnfsf15,Traf2,Flt1,Pdgfb,Nek6,Ranbp2,Il18,Irak2,Pim1,Cd200,Ripk3,Trib1,Tlr6,Jak2,Crkl,Rasgrp1,Sdc4,Cdkn1a,Angpt1,Met,Pik3r5,Mapkbp1,Tnf,Mdfic,Daxx,Kitl,Tpx2,Syk,Agrn,Il12b,Il1rn,Tlr1,Gadd45b,Cd74,Malt1,Gdf15,Egr1,Rgcc,Fgr,Map3k6,Cd40,Bmp2,Prnp,Thbs1,Rapgef2,Hsph1,Mmd,Higd1a,Ccnd2,Acsl1,Pik3r6,Il1b,Trib3,Lgals9,Pdgfc,Sirt1,Mlkl,Ccnd1,Cdk5r1,Psmd10,Lyn,Htr2b,Lmo4,Ikbkg |
| 6.407e-17 | -37.29 | GSE17721_POLYIC_VS_CPG_1H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_1H_BMDC_DN | 191 | 54 | 15632 | 1249 |
Kpna3,Ell2,Cd200,Rcsd1,Tlr2,Tnip1,Rabgef1,Zfp36,Nfkbib,Rnf19a,Nck1,Pgs1,Nr1h3,Gadd45b,Adhfe1,Bcl2l11,Sqstm1,Spic,Fos,Tiparp,Peli1,Dtnb,St3gal1,Ptger4,Rnf19b,Rtn1,Serpinb9,Fpr1,Slfn3,Il1rn,Il15ra,Dcbld2,Hcar2,Tfec,Slfn4,Lcp2,Samsn1,Cd274,Med21,Stxbp3,Hk2,Adora2a,Cd14,Apaf1,Phldb1,Acpp,Tbc1d1,Rab21,Rffl,Dusp8,Tlk2,Nfkbie,Errfi1,Prdx5 |
| 6.731e-17 | -37.24 | MARZEC_IL2_SIGNALING_UP | MSigDB lists | MARZEC_IL2_SIGNALING_UP | 111 | 40 | 15632 | 1249 |
Tnfsf14,Il10,Ptch1,Osm,Birc3,Ccne1,Tnfrsf1b,Dusp6,Eef1e1,Hk2,Il18rap,Phlda1,Trib3,Acvr1b,Pim1,Ier3,Serpinb9,Prkx,Tnfsf10,Hspa1a,Gadd45b,Ccnd1,Dusp4,Stat3,Myc,Dusp2,Pnp2,Cish,Il1a,Ccnd2,Cdk5r1,Socs1,Mapkapk2,Lif,Csrnp1,Spred1,Ahr,Rras2,Tnfrsf8,Bmp2 |
| 6.770e-17 | -37.23 | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | 210 | 57 | 15632 | 1249 |
Gna15,Casp8,Casp4,Tnfrsf1b,Ltbp2,Procr,Ampd3,Phf11d,Tlr2,Acsl1,Dram1,Itga5,Clcf1,Siglece,Rbms1,Msr1,Rab32,Cnn2,Nod2,Fcgr2b,Ctsc,Pdpn,Il4ra,Hk3,Phf11c,Plau,Phf11a,Lcp2,Serpine1,Slamf8,Tgfbi,Nr4a3,Lox,Ptger4,Il15ra,Dcbld2,Plaur,Thbs1,Acpp,Swap70,Timp1,Dse,Mgat1,P4ha2,Phf11b,Casp1,Slc16a3,Sat1,Rab11fip1,Ly75,Plk3,Itga4,Mvp,Tnfaip3,Relb,Batf,Cd14 |
| 6.806e-17 | -37.23 | GSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN | 179 | 52 | 15632 | 1249 |
Ifi44,Pnp2,Batf2,Casp3,Dhx58,Hspa2,Treml2,Slc2a1,Rbbp8,1600014C10Rik,Smg7,Nod1,Cd83,Daxx,Notch1,Pml,Csrnp1,Dtx3l,Upp1,Ube2l6,Rapgef2,Sh3bp4,Ascc3,Cnp,Ppm1k,Slfn9,Trafd1,Naa25,Il12b,Nr4a3,Slfn8,Dnaja1,Znfx1,Rbm43,Sgcb,Hinfp,Tpx2,Il4ra,Tmtc2,Ccnd2,Nfkbib,Trim14,Hat1,Cd69,Abtb2,Ubr4,Kdr,Cdkn1a,Stat1,Dgkh,Ddx4,Trib1 |
| 6.863e-17 | -37.22 | GSE8835_HEALTHY_VS_CLL_CD8_TCELL_DN | MSigDB lists | GSE8835_HEALTHY_VS_CLL_CD8_TCELL_DN | 173 | 51 | 15632 | 1249 |
P4ha2,Slc15a3,Errfi1,Kdm5b,Cers6,Ch25h,Gbp3,Gys1,Rnaset2a,Ppp1r15a,Osm,Serpine1,Caml,Antxr1,Bst1,G3bp2,Csf3,Smox,Hp,Tgfbi,Pilrb1,Bambi,Gcnt2,Ptges,Fam43a,Aoah,Rnf114,Ptpn2,Trip10,Fcgr2b,Scarf1,Ppfia3,Nfkbiz,Cx3cl1,Il4ra,Pilrb2,S100a8,Tnfsf14,Heatr6,Slpi,Egln3,Mtdh,Mmp9,Oasl1,Lpar1,Whamm,Cd300lf,Tnfaip2,Tnip1,Fam162a,Rnaset2b |
| 6.903e-17 | -37.21 | GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION | 276 | 67 | 15632 | 1249 |
Cd38,Ccdc88b,Cd83,Fgr,Cd74,Malt1,H2-Q7,Prdm1,Hlx,Pnp2,Cd40,Bcl6,H2-Q6,Traf2,Src,Axl,Hsph1,Il1b,Thbs1,Vcam1,Il12b,Nr4a3,Il18,Map3k8,Ptafr,Adora2b,Ripk2,H2-Ab1,Cd55,Bst1,Il12rb1,H2-Aa,Icosl,Pik3r6,Cd274,Cd86,Ccl5,Plek,H2-Eb1,Tnfrsf14,Cd80,Il15,Irs2,Il4ra,Nlrp3,Nck1,Ap3b1,Nod2,Mmp14,Stap1,Peli1,Il6,Ccl12,Syk,H2-Q4,Spn,Cdkn1a,Clcf1,Jak2,Lyn,Egr3,Ebi3,Tnfsf4,Rasgrp1,Rictor,Cav1,Tnfsf14 |
| 7.805e-17 | -37.09 | SMID_BREAST_CANCER_BASAL_UP | MSigDB lists | SMID_BREAST_CANCER_BASAL_UP | 586 | 108 | 15632 | 1249 |
Fabp7,Ifi211,Isg20,Cnn3,Slpi,Lmo4,Plod2,Mndal,S100a8,Lhx2,Nfil3,Rbms1,Fscn1,Dnajb4,Odc1,Ifi204,Lyn,Dennd2a,Ifrd1,Mid1,Pla2g4a,Mmp14,Hmga1,Ppp1r14b,Bcl2a1b,Sod2,Ifi207,Col4a2,Slc16a1,Rtp4,Cx3cl1,Ifi214,Tpx2,Ddit4,Tmeff1,Col11a2,Asns,Cdyl,Ccl5,Stip1,Adora2b,Rcan1,Ogfrl1,Phgdh,Cp,Itgb8,Ifi209,Slc25a37,Klf6,Cd38,Atp11a,Upp1,Ifih1,Smpdl3b,Ifi203,Met,Trip13,Plscr1,Marco,Lcn2,Psat1,Ccne1,Trem1,Socs3,Chst11,Sdc2,Edn1,Peli1,Myc,Pdpn,Cenpe,Ccl12,Tap1,Angpt1,Rnd3,Rras2,Plagl1,Pttg1,Lrp8,Wars,Slc2a6,Slc7a5,Phlda1,Ifi208,Lad1,Igf2bp2,Bcl2a1a,Serpinb2,Prkx,Clic4,Mob3b,Slamf8,Slc43a3,Ptgs2,Lox,Cxcl10,Uchl1,Bcl2a1d,Ifi205,Gpsm2,Eno1,Ifi213,Apobec3,Myo10,Icam1,St3gal6,Mcm10,Pml |
| 7.963e-17 | -37.07 | response to chemical | biological process | GO:0042221 | 4862 | 462 | 20694 | 1406 |
Cx3cr1,Il10,Cnp,Ppp1r15b,Irf1,Gk,Serpina3g,Cmklr1,Gbp7,Hspa1a,Mmp14,Tgtp2,Ccr3,Ptgir,Casp7,Itga4,Gclm,Hvcn1,Esd,Fas,Socs7,Dnaja1,Edn1,Sema4c,Ifi203,Hap1,Casp1,Jarid2,Ldlr,Il18rap,Idi1,Casp4,Nfkbil1,Mul1,Ripk2,Traf2,Ifna5,Gfi1,Sele,Zc3h12a,Il18,Sbds,Slc31a1,Nfkbib,Atf3,Ccl12,Asah2,Slc13a3,Prdx1,Angpt1,Fam162a,Jun,Plk3,Tnf,Daxx,Il1a,Cited2,Selenow,Stxbp1,Bambi,Cd180,Il13ra1,Gclc,Arid5b,Slc25a12,Nqo1,Slc16a1,Irs2,Kat2b,Icam1,Mtdh,Gbp8,Pfkl,Cd86,Ppp2r2a,Pik3cd,Hsph1,Rapgef2,Plscr1,Ifit2,Ier2,Ptgs2,Ifi213,Nfil3,Cyfip1,Slpi,Klf6,H2-Eb1,Lgals9,Il15ra,Cd274,Cd83,Ccl22,Etv3,Mmp9,Sirt1,Klf7,Cav1,Osm,Cxcl11,Acod1,Itpr1,Birc3,Ifit3,Slamf8,Nfkbia,Adrb2,Slc30a1,Evl,Ccl2,Stat5a,Pdpn,Socs1,Pnpt1,Eif2ak2,Gm4951,Eef1e1,Kif5c,Ifna2,Socs3,Ptk2,Slc25a22,Ch25h,Kdm5b,Fosb,Nr1h3,Ccl8,Gm12185,Pdgfrb,Ptpn2,Fzd5,Dnajb2,Nupr1,Csf1,Gsr,Il15,Hspa2,Rhoq,Fpr2,Stat2,Snx10,Pdk3,Map2k1,Nr3c1,Peli1,Slc25a25,Flt1,Zc3hav1,Akt3,Gramd1a,Nlrp3,Ifi211,Ifi47,Tnfrsf1b,Rnf139,Itga9,Pgk1,Inhba,Irf7,Tnfaip3,Ddx58,Vasn,Sphk1,Lrp11,Timp1,Jak2,Tlr6,Ifi207,Trim56,Casp8,Pla2g4a,Etv5,Cp,Abcc1,Abtb2,Ifna6,Stra6l,Gpr35,Acvrl1,Agtrap,P2ry12,Mt2,H2-Aa,Cacybp,Gm5431,Srxn1,P2ry13,Il12b,Agrn,Mefv,Ifitm1,Bnip3,Ifi214,Ednrb,Cd14,Tnip3,Clic4,Stxbp3,Tmem67,Bmp2,Nrp2,Lhx2,Cpeb4,Nmral1,Il2rg,Saa3,Phgdh,Lox,Acvr1b,Dusp1,Trib3,Acp2,Il1b,Isg15,Ifna1,Acp5,Nfkb1,Keap1,Cdk5r1,Prkce,Slc30a4,Ifi205,Tlr3,Ifnar1,S100a8,Nr4a1,Acvr1,Tnfsf4,Hdac1,Cdc42ep4,Shfl,Ehd1,Egln3,Aim2,Adora2a,Abcb1a,Atp2b4,Ptger4,Mmp13,Irak3,Zfp36,Serpine1,Nod2,Flrt2,Igtp,H2-Q7,Tap2,Trim21,Stap1,Homer1,Cmpk2,Xcr1,Ptprj,Nmi,Stx11,Ass1,Nfkbie,Cd69,Gcnt2,Csf3,Cdc42ep2,Ifi208,Irgm2,Ifna4,Sesn3,Gbp4,Tab2,Nos2,Scn1b,Cxcl9,Pid1,Gm4841,Notch1,Irak2,Cd300lf,Tiparp,Pim1,Hmox1,Tlr2,Uaca,Flnb,Gsta3,Zyx,Pml,Ccr1,Rab20,Noct,Col4a2,Sod2,Fzd1,Ifi204,Ccl3,Sh3bp4,Stat4,Syk,Pde3b,Ccl4,Cd74,Tlr1,Pde4b,Oas2,Actb,Malt1,Junb,Fpr1,Nod1,Srm,Ifnb1,Cdkn2d,Ccl5,Cxcl2,Vrk2,Igf1r,Larp1,Phip,Nox1,F830016B08Rik,Stoml1,Timeless,Cd38,Tank,Hspa1b,Abr,Fos,Ahrr,Tent4a,Atm,Cd80,Higd1a,Acsl1,Ifit1,Gbp2b,Hp,Trim13,Axl,Irf8,Sell,Lyn,Il4ra,Slc7a11,Ifi209,Ahr,Usp18,Ptch1,Htr2b,Stip1,Ezr,Ddit4,Glrx,Slc9a1,Gbp2,Tlr9,Pf4,Apaf1,Cxcl1,Ccl7,Mecp2,Vegfc,Iigp1,Ccl9,Zeb1,Olfr56,Myc,Htr2a,Fcgr4,Dcp1a,Spry2,Dock4,Pde1b,Tgtp1,Ifih1,Klf2,Csf3r,Ntng2,Ccrl2,Birc2,Lcn2,Hcls1,Gbp3,Sema3c,H2-Ab1,Egr3,Stat3,Src,Lpar1,Lrch1,Ikbke,Serpina3f,Ebi3,Ero1l,Pdgfb,Ak4,Klrk1,Cxcl10,Xaf1,Ptafr,Mndal,Optn,Abcc4,Trib1,Il12rb1,Cxcl3,Adar,Ripk3,Crkl,Stat1,Flrt3,Prdx5,Gch1,Arid5a,Fcgr2b,Me1,Irgm1,Myd88,Serp1,Met,Cx3cl1,Kdr,Egr2,Gbp9,Il1rn,Cgas,Kdm6b,Gdf15,Ppp1r15a,Calcrl,Rab10,Egr1,Rgcc,Fut8,Ext1,Cxcl14,Hmgcs1,Eno1,Vcam1,Rel,Sema4a,Ctsc,Mt1,Thbs1,Prnp,Trem1,Vasp,Ciita,Cflar,Jag1,Il6,9930111J21Rik1,Hif1a,Mapkapk2,Mdm2,Slc7a2,Pdgfc,Palld,Relb,Ccnd1,Nr4a3,Hk2,Gja1,Itgav,Rtp4,Casp3 |
| 8.451e-17 | -37.01 | regulation of MAP kinase activity | biological process | GO:0043405 | 305 | 65 | 20694 | 1406 |
Tlr9,Pik3r5,Met,Map2k4,Rasgrp1,Syk,Dusp6,Map3k8,Kitl,Eif2ak2,Mdfic,Mapkbp1,Tnf,Dusp4,Gadd45g,Gdf15,Aida,Htr2a,Pde5a,Irak3,Fzd5,Pdgfrb,Cd74,Spred3,Gadd45b,Il1rn,Cd40,Dnaja1,Igf1r,Map3k6,Dusp16,Edn1,Nod2,Spry2,Uchl1,Thbs1,Src,Dusp5,Dusp2,Map2k1,Bmp2,Ptprj,Pdgfb,Spred1,Dusp1,Flt1,Traf2,Ksr1,Mul1,Ripk2,Lpar1,Dusp8,Mlkl,Pdgfc,Rgs14,Trib3,Il1b,Pik3r6,Crkl,Jak2,Tlr6,Htr2b,Cav1,Lyn,Trib1 |
| 8.595e-17 | -36.99 | GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_DN | MSigDB lists | GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_DN | 186 | 53 | 15632 | 1249 |
Ccl22,Etv3,Tnfrsf14,Tap1,Il15,Sdc4,Cd80,Slamf7,Trip10,Gadd45b,Nfkbia,Sqstm1,Edn1,Irf1,Ebi3,Cdkn1a,Fscn1,Tnip1,Tnfaip2,Rel,Birc3,Tnfrsf1b,Nfkb1,Zeb1,Psme2,F11r,Psmb10,Traf1,Marcksl1,Psme1,Relb,Mvp,Tnfaip3,Lipg,Cd40,Tank,Stat5a,Dusp1,Cers6,Nr3c1,Ly75,Il15ra,Trafd1,Snn,Nfkb2,Plk2,Pde4b,Txn1,Map4k4,Tbc1d13,Icosl,Nrp2,Slc2a6 |
| 8.788e-17 | -36.97 | GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN | 162 | 49 | 15632 | 1249 |
Isg15,Cd74,Usp18,Pml,H2-Q7,Etv5,Ifi209,Oas3,Ifi205,H2-Q6,N4bp1,Ifi213,Rsad2,Ccdc86,Ifi44,Slc43a3,Grina,Oas1g,Larp1,Herc6,Rnf19b,Ifit1bl2,Rgl1,Oas2,Ifi208,Nmi,Ifi214,Ifi207,Zyx,H2-Q4,Ifit1bl1,Eif2ak2,Igsf6,Mthfd2,Ifit3b,Tlr2,Ifi204,Ptgir,Oasl1,Ifi35,Actb,Mndal,Ifit3,Xaf1,Ifi203,Oas1a,Plscr1,Cnn3,Ifi211 |
| 8.847e-17 | -36.96 | GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_DN | 180 | 52 | 15632 | 1249 |
Glrx,Rsbn1,Plat,Gcnt2,Slamf8,Cox18,St3gal1,Ripk2,Smc5,Wars,Sh3bp4,Dgka,Fosb,Csrp1,Rnf34,Gbp3,Mxd1,Glipr2,Mdm2,Tlk2,Atp13a1,Arhgef3,Ankrd17,Dusp1,Klf6,Ddhd1,Plod3,Casp1,Ap3m2,Arf4,Tax1bp1,Ebi3,Cpeb4,Ccrl2,Sirt1,Cysltr2,Casp8,Psmb8,Chmp4b,Enpp4,Atp11b,Cd80,Xrn1,Tra2a,Parp14,Nat2,Fos,Trip10,Dnaja1,Gramd1a,Spn,Rnf114 |
| 8.847e-17 | -36.96 | GSE17721_LPS_VS_POLYIC_16H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_16H_BMDC_DN | 180 | 52 | 15632 | 1249 |
Nlgn2,Rbms1,Kdr,Ldlr,Ccl4,Ifit3b,Stat4,Mmd,Ifit3,Plekha2,Ccne1,Rbms2,Rbm43,Kat2b,Tpx2,Gmppb,Ddx60,Cept1,Rin2,Triobp,Parp9,Edn1,Dcbld2,Gcnt2,Grina,Slc43a3,Fam53c,Psmb6,Oas2,Tbc1d13,Parp12,Scn1b,Cd86,Jarid2,Slc7a8,Ccnj,Brd2,Myo10,Prpf38a,Bfar,F11r,Sphk1,Irf2,Glipr2,Tlk2,Atp13a1,Rsad2,Ythdf1,1110038F14Rik,Nr3c1,Sat1,Rbbp8 |
| 8.847e-17 | -36.96 | GSE17721_CTRL_VS_POLYIC_12H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_12H_BMDC_DN | 180 | 52 | 15632 | 1249 |
Atp13a1,Hdac1,Plekhf2,Phldb1,Timp1,Cd83,Bfar,Plagl2,Gbp2,Mcmbp,Pml,Gbp3,Tab2,Tyk2,Ccl5,Cacybp,Fzd5,Gca,Slc29a3,Mitd1,Epsti1,Pkp4,Ripk2,Clec5a,Pim1,Ccl2,Pcx,Vcan,Rnf114,Rab32,Hmga1,Znfx1,Zbp1,Kif9,Hinfp,Ciita,Angpt1,Slc28a2,Palld,Stxbp1,Ociad1,Cnn3,Syne2,Rbms1,Arf4,Fscn1,Cdkn1a,Dusp16,Igf1r,Dtx2,Ddx4,Ms4a6d |
| 8.897e-17 | -36.96 | MODULE_44 | MSigDB lists | MODULE_44 | 298 | 70 | 15632 | 1249 |
Zyx,Ifit1bl1,Dusp2,Ctsc,Ikzf1,Il4ra,Ifi214,Sdc1,Tap1,Ifi207,Tnfrsf14,Cd34,Casp4,Lmo4,Mndal,Cav1,Ifit3,Irf8,Ikbkg,Tnfrsf1b,Birc3,S100a8,Ifi203,Cd69,Plscr1,Slpi,Isg20,Ifi211,Ifit3b,Ifi204,Stat1,Mmp9,Ifi35,Hcls1,Rgs1,Adam19,Birc2,Bcl6,Ifi209,Ifi205,Mtus1,Psmb9,Itpr1,Stat5a,Ifi213,Ccng2,Fgl2,Ifi44,Isg15,Sell,Nupr1,Rhoh,Tnfaip3,Crim1,Sla,Cd14,Lcp2,Psd4,Ifit1bl2,Dgka,Hap1,H2-Aa,Ifi208,Ube2l6,Ddit4,Il2rg,Tgfbi,H2-Ab1,Acp2,Vcam1 |
| 8.940e-17 | -36.95 | negative regulation of viral process | biological process | GO:0048525 | 99 | 35 | 20694 | 1406 |
Hdac1,Trim26,Oas3,Plscr1,Pml,Trim56,Isg20,Parp10,Slpi,Apobec3,Ccl4,Oas1a,Shfl,Jun,Oasl2,Rsad2,Fam111a,Oasl1,Tnf,Eif2ak2,Ifitm1,Zc3h12a,Zfp36,Zc3hav1,Trim13,Oas1b,Isg15,Trim21,Stat1,Resf1,Ifnb1,Oas1g,Ccl5,Adar,Trim14 |
| 9.106e-17 | -36.94 | regulation of apoptotic signaling pathway | biological process | GO:2001233 | 412 | 78 | 20694 | 1406 |
Bcl2l11,Plscr1,Src,Bcl2a1a,Thbs1,Hsph1,Map2k1,Ctsc,Casp2,Hif1a,Higd1a,Traf2,Ptgs2,Cflar,Traf1,Bcl2a1d,Mul1,Sirt1,Mmp9,Ier3,Mdm2,Il1b,Acsl5,Pmaip1,Grina,Ikbkg,Itgav,Jak2,Ripk3,Psmd10,Hmox1,Osm,Inhba,Cav1,Tnfaip3,Tnfsf10,Pf4,Apaf1,Hdac1,Nck1,Asah2,Tnfsf4,Eya4,Acvr1,Plaur,Pml,Casp8,Cx3cr1,S100a8,Atf3,Bcl2a1b,Rnf34,Eef1e1,Ppp2r1b,Adora2a,Daxx,Cx3cl1,Tnf,Fam162a,Sod2,Rffl,Plagl2,Ptpn2,Bnip3,Myc,Gclm,Gclc,Sgk3,Cd74,Phip,Nox1,Dnaja1,Icam1,Fas,Nupr1,Cdkn2d,Ifnb1,Serpine1 |
| 9.212e-17 | -36.92 | G_IRG_dom | interpro domains | IPR030385 | 16 | 15 | 19984 | 1430 |
Iigp1,Gm5431,Ifi47,Gm12185,Irgm1,Gm4841,F830016B08Rik,Tgtp1,9930111J21Rik2,9930111J21Rik1,Irgm2,Irgq,Gm12250,Igtp,Gm4951 |
| 1.022e-16 | -36.82 | GO_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 877 | 142 | 15632 | 1249 |
Dusp8,Cish,Dbnl,Casp3,Psma6,Ccnd1,Hsph1,Src,Dusp1,Cd40,Psmb9,Rgs14,Bmp2,Nod1,Mdfic,Ripk3,Daxx,Pml,Hhex,Malt1,Psme1,Ube2e1,Socs1,Fgr,Tnfsf15,Pdgfb,Txn1,Pik3r6,Thbs1,Uchl1,Dusp5,Ptprj,Fpr1,Il12b,Cxcl10,Pim1,Il6,Ppp2r5a,Edn1,Spry2,Nod2,Pik3r5,Flrt3,Cenpe,Nlrc5,Map3k6,Flt1,Psmd10,Adar,Htr2a,Angpt1,Mark2,Atp2b4,Lrp8,Tlr6,Mapkapk2,Arrdc4,Ccnd2,Rasgrp1,Sirt1,Ccne1,Psmb8,Prkar2b,Socs7,Igf1r,Socs3,Acsl1,Adrb2,Aida,Hspa2,Errfi1,Tnf,Traf2,Irak3,Tnfaip3,Mvp,Pdgfc,Rgs3,Psmb10,Tab2,Cd74,Rapgef2,Ccl5,Dusp6,Map2k1,Pdgfrb,Fzd5,Lcp2,Flrt2,Kitl,Irak2,Pilrb1,Htr2b,Il1b,Psmb6,Ripk2,Crkl,Tlr3,Map3k8,Trib3,Adora2b,Stap1,Dusp2,Gadd45g,Dusp4,Pde5a,S1pr2,Syk,Gadd45b,Eif2ak2,Dnaja1,Ptpn2,Pilrb2,Sdc4,Rbl1,Dusp14,Spred1,Cdkn2d,Nck1,Tpx2,Irs2,Mul1,Cdk5r1,Ubash3b,Kat2b,Psme2,Csf1,Mmd,Ikbkg,Dcun1d3,Atm,Lmo4,Cav1,Rap2c,Jak2,Cdkn1a,Dusp16,Tlr9,Ptk2,Lyn,Lpar1,Trib1 |
| 1.147e-16 | -36.70 | GSE2585_CD80_HIGH_VS_LOW_AIRE_KO_MTEC_UP | MSigDB lists | GSE2585_CD80_HIGH_VS_LOW_AIRE_KO_MTEC_UP | 181 | 52 | 15632 | 1249 |
Tpi1,Abr,Nfkbiz,Pilra,Flrt3,Rab32,Spsb1,Zyx,Gpr18,Il6,Fcgr2b,Vcan,Denr,Cd200,Il13ra1,Filip1l,Acsl1,Tnfaip2,Adam19,Orai2,Trem1,Ahrr,Nos2,Heatr6,Cav1,Rel,Itgal,Met,Egln3,Jag1,Ch25h,Traf1,Il1a,Sla,Irak3,Cst7,Dusp1,Acpp,Rhoq,Hmox1,Zc3h12a,Fpr1,Tgfbi,Grina,Htr2b,Myadm,Slc4a7,Osm,Antxr1,Cxcl2,Sh3bp4,Csf3 |
| 1.176e-16 | -36.68 | GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_DN | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_DN | 169 | 50 | 15632 | 1249 |
Itgav,Trim36,Nr4a1,Nfkbia,Ppfibp1,Irs2,Arl4a,Atf3,Nfkbiz,Kctd12,Rap1gap2,Il18rap,Ccrl2,Stat4,Zfp36,Srxn1,Cysltr2,Plod2,Gfi1,Cdkn1a,Ldlr,Ier3,Mafg,Odc1,Kif5c,Ell2,Sema4c,Cish,Slc39a4,Nr3c1,Ehd1,Mdfic,Sla,Mapkbp1,Lif,Plk3,Malt1,Itga4,Ppp2r3a,Arl5b,Btg2,Fosb,Samsn1,Asns,Ccl5,Bambi,Vcam1,Nsmaf,Il18,Zc3h12a |
| 1.355e-16 | -36.54 | GSE17721_CTRL_VS_CPG_8H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_8H_BMDC_DN | 194 | 54 | 15632 | 1249 |
Plscr1,Eef1e1,Dach1,Cav1,Plekha2,Lmo4,Lap3,Dusp16,Lhx2,Mtdh,Mthfd2,Rcsd1,Parp14,Ppp2r5a,Stard5,Ifnb1,Nfkbia,Gramd1a,Morc3,Ccl12,Sqstm1,Agrn,Zbp1,Abr,Mapkapk2,Lrp8,Kat2b,Gbe1,Nr1h3,Stxbp3,Hk2,Igsf9,Myo1b,Samsn1,Cnp,Vps54,Gtpbp2,Ralgds,Mitd1,Ptges,Hcar2,Ripk2,Arid5b,Gbp9,Gbp4,Hdac1,Fgl2,Stk40,Ddhd1,Ttc39c,Cutc,Plagl2,Prpf38a,Gbp2 |
| 1.427e-16 | -36.49 | GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | 188 | 53 | 15632 | 1249 |
Slc29a3,Ikbke,Epsti1,Pkp4,Ripk2,Cxcl10,Il2rg,Tmem229b,Tyk2,Gch1,Csrp1,Cd274,Lad1,Sla,Cd83,Sgk3,Rgs3,Psme1,Ifih1,Spata13,Cd74,Gbp4,Gbp9,Gypc,Ifnar1,Ifit2,Mgat1,Arhgef3,Asf1a,Vrk2,Stat1,Rcsd1,Pik3cd,Psme2,Rasgrp1,Stat4,Mmd,Tnfrsf1b,Psmb8,Ptch1,Fbxo4,Tap1,Atp11b,Prnp,Cyth3,Stap1,Irgm2,Il18bp,Ap3b1,Phlpp1,Bcl2l11,Nr4a1,Spn |
| 1.485e-16 | -36.45 | GSE22886_DC_VS_MONOCYTE_DN | MSigDB lists | GSE22886_DC_VS_MONOCYTE_DN | 182 | 52 | 15632 | 1249 |
Psmb10,Sell,Itga4,Ier2,Irak3,Gbp2,Crlf3,Cd14,Csf3r,Rhbdf2,Klf6,Dusp1,Casp1,Arhgap26,Cebpd,Fpr1,Cd55,Smc5,Sp110,Tnfsf10,Gca,Klf2,Irf7,Gch1,Dusp6,Ext1,Irs2,Cdkn2d,Il15,Fos,Ptpn2,Cx3cr1,Gsdmd,Gadd45b,4932438A13Rik,Nod2,Vcan,Peli1,Irf1,Lyn,Pik3cd,Tlr2,Igf1r,Notch2,Pid1,Itgal,P2ry2,Sik3,Tnfrsf1b,Rap1gap2,Plscr1,Zfp36 |
| 1.485e-16 | -36.45 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP | 182 | 52 | 15632 | 1249 |
Hk1,Gem,Sco1,Tifa,Zfp36,Nfkbib,Ccrl2,Socs3,Rab20,Ldlr,Tnfaip2,Ets2,Hmga1,Ppp2r5a,Il6,Lrch1,Usp25,Irs2,Enpp4,Pde4b,Rrs1,Ppp1r15a,Cd86,Phlda1,Maff,Cxcl2,Nfkbid,Pcgf5,Kdm6b,Map3k8,Il12b,Nr4a3,Ptgs2,Serpinb2,Rsbn1,Trafd1,Il1b,Txnrd1,Tnf,Ehd1,Dse,Slc15a3,Csrnp1,Prdm1,Marcksl1,Ch25h,St3gal6,Traf1,Atp11a,Icam1,Smg7,Tnfaip3 |
| 1.485e-16 | -36.45 | GSE22432_MULTIPOTENT_PROGENITOR_VS_CDC_UP | MSigDB lists | GSE22432_MULTIPOTENT_PROGENITOR_VS_CDC_UP | 182 | 52 | 15632 | 1249 |
Dgka,Asah2,Gch1,Brd2,Slc7a8,Trafd1,Slfn9,Plcl2,Arid5b,Slamf8,Tlr3,Mlkl,Treml2,Mafk,Ccnd1,Tpst1,Cst7,Ddhd1,Dpy19l1,Bfar,Ifih1,Gbp3,Cd180,Pml,Nupr1,Csrnp1,Psme1,Pou2f2,Psme2,Gbp7,Gem,Plekhg1,Acsl1,Tmod3,Ebi3,Endod1,Peli1,Slfn8,Slc7a11,Slc28a2,Slfn5,Samhd1,Tap1,Chmp4b,Gpc1,Col4a2,Herc3,Rbms2,Aldh1b1,Coa5,Usp25,Fas |
| 1.489e-16 | -36.44 | positive regulation of leukocyte cell-cell adhesion | biological process | GO:1903039 | 203 | 51 | 20694 | 1406 |
H2-Aa,Syk,Ap3b1,Tnf,Socs1,Stat5a,Ikzf1,Ccl2,Irf1,Nck1,Tnfsf4,Rasgrp1,Vcam1,Il15,Icam1,Ccl5,Nfkbid,Malt1,Itga4,Bcl6,Il12b,Cd74,Ccdc88b,Ptafr,Cd80,Il6,Il2rg,Hlx,Ripk2,Icosl,Tnfsf9,H2-Ab1,Egr3,Spn,Hsph1,Cd86,Nfkbiz,Nr4a3,Tnfsf14,Il12rb1,Il4ra,Tnfrsf14,Cav1,Il18,Itgal,Nlrp3,Cd83,Cd274,Il1b,Pik3r6,Lgals9 |
| 1.494e-16 | -36.44 | HALLMARK_APOPTOSIS | MSigDB lists | HALLMARK_APOPTOSIS | 158 | 48 | 15632 | 1249 |
Timp1,Tnf,Casp1,Ccnd1,Gsr,Casp3,Sat1,Il1a,Cd38,Cd14,Bmp2,Pdgfrb,Gch1,Btg2,Il18,Hmox1,Il1b,Tnfsf10,Plat,Dnaja1,Jun,Gadd45b,Sqstm1,Sod2,Bcl2l11,Ifnb1,Il6,Ccnd2,Fas,Atf3,Tap1,Tspo,Gna15,Cav1,Casp4,Casp8,Eno2,Birc3,Casp2,Cd69,Isg20,Irf1,Ier3,Casp7,Ptk2,Egr3,Cdkn1a,Cflar |
| 1.524e-16 | -36.42 | GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_UP | MSigDB lists | GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_UP | 176 | 51 | 15632 | 1249 |
Egln3,Fam20c,Ccl4,Cdkn1a,Trem1,Pfkl,Esd,Ell2,Socs3,Tlr2,Ier3,Pdpn,Il6,Myc,Spry2,Fcgr2b,Ppp1r14b,Bcl2a1b,Jun,Ets2,Hmga1,Plau,Sdc4,Tpi1,Egr1,Il4ra,Phlda1,Cxcl2,Maff,Ccr1,Osm,Tap2,Ikbke,Bcl2a1a,Ptges,Pf4,Ldha,Slc15a3,Ccdc86,Micall2,Gpr84,Bcl2a1d,C1ra,Slc2a1,Hspa1a,Gys1,Cd14,Csrnp1,Nupr1,Upp1,F11r |
| 1.531e-16 | -36.42 | IL2_UP.V1_UP | MSigDB lists | IL2_UP.V1_UP | 164 | 49 | 15632 | 1249 |
Lrp8,Egr1,Ahr,Fos,Flt1,Gadd45b,Dusp4,Dusp2,Spry2,Itga9,Trib1,Pim2,Rac3,Egr3,Ap3m2,Adam19,Siglece,Ptch1,Tnfsf14,Il10,Tnfrsf1b,Abtb2,Il18rap,Cd69,Kctd12,Sphk1,Socs1,Il1a,Lif,Aim2,Rgs3,Bmp2,Rhbdf2,Klf6,Egr2,Rab11fip1,Cish,Pim1,Kcna3,Tlr3,Osm,Fzd5,Dusp6,Junb,Maff,Stx11,Hk2,Cxcl2,Slc7a5 |
| 1.540e-16 | -36.41 | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | 170 | 50 | 15632 | 1249 |
Nr4a1,Tiparp,Fos,Dusp2,Usp25,Atf3,Arl4a,Etv3,Pfkfb3,Mcm9,Rel,Dcp1a,Cd69,Socs3,Egr3,Rgs1,Nfil3,Cdkn1a,Dusp1,Ifit2,Otud1,Egr2,Sat1,Dhx58,B3gnt5,Mafk,Lif,Csrnp1,Hif1a,Cd83,Junb,Jarid2,Nampt,Fosb,Med21,Osm,Plk2,Samsn1,Arl5b,Btg2,Stx11,Wars,Ripk2,Fam53c,Ptger4,Nr4a3,Cxcl10,Ptgs2,Serpinb2,Cxcl1 |
| 1.618e-16 | -36.36 | GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN | MSigDB lists | GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN | 88 | 35 | 15632 | 1249 |
Il1b,Cxcl1,Tnfsf10,Ifi204,H2-Ab1,Ptger4,Tnfsf4,Cd200,Inhba,Ifi203,Cxcl2,Ifi211,H2-Aa,Ifi208,Mndal,Birc3,Dusp6,Ifi207,Enpp4,Ppfibp1,Gbp2,Sell,Ifi214,Ch25h,Hlx,Tra2a,Rbpms,Optn,Ccng2,Ifi205,Cd40,Tcf4,Ifi209,Ifi213,Sod2 |
| 1.628e-16 | -36.35 | cytokine activity | molecular function | GO:0005125 | 214 | 53 | 20217 | 1400 |
Il12b,Tnfsf8,Il15,Ccl5,Cxcl3,Ccl22,Tnfsf9,Csf3,Cxcl14,Ifna4,Nampt,Cxcl10,Il6,Ifna2,Ifna5,Tnf,Ifna1,Cxcl11,Timp1,Cxcl1,Lif,Cxcl2,Pf4,Ccl4,Il10,Cxcl9,Il27,Cx3cl1,Inhba,Tnfsf4,Ifna6,Il1b,Kitl,Ccl12,Clcf1,Il1a,Il1rn,Osm,Tnfsf10,Gdf15,Ccl7,Ebi3,Edn1,Csf1,Bmp2,Ccl9,Ccl3,Ifnb1,Il18,Ccl2,Tnfsf15,Ccl8,Tnfsf14 |
| 1.641e-16 | -36.35 | regulation of mononuclear cell proliferation | biological process | GO:0032944 | 225 | 54 | 20694 | 1406 |
Stat5a,Slfn1,Syk,H2-Aa,Bst1,Il10,Cdkn1a,Sdc4,Tnfsf4,Fcgr2b,Tlr9,Prdm1,Il27,Nck1,Irf1,Myd88,Irs2,Il15,Ccl5,Csf1,Cd40,Vcam1,Cd74,Ccdc88b,Il12b,Pde5a,Bcl6,Ripk2,Cd80,Il6,Atm,Arg2,Cd86,Spn,Cd38,Icosl,H2-Ab1,Peli1,Prnp,Tnfsf9,Il12rb1,Tarm1,Tnfrsf14,Lyn,Ripk3,Clcf1,Ahr,Casp3,Lgals9,Cd274,Il1b,Il18,Itgal,Tnfrsf1b |
| 1.727e-16 | -36.29 | regulation of interleukin-1 beta production | biological process | GO:0032651 | 74 | 30 | 20694 | 1406 |
Ifi211,Acp5,Malt1,Fzd5,Gsdmd,Zc3h12a,Mefv,Nlrp3,Mndal,Sphk1,Ifi205,Errfi1,Ifnar1,Jak2,Nod1,Nod2,Tnfaip3,Hk1,Tlr2,Egr1,Casp4,Casp8,Pml,Casp1,Cx3cr1,Arg2,Ripk2,Ccl3,Ifi204,Aim2 |
| 1.834e-16 | -36.24 | GSE29618_MONOCYTE_VS_MDC_UP | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_UP | 189 | 53 | 15632 | 1249 |
Klf7,Pilra,Il15,Irs2,Nlrp3,Dmxl2,Egr1,Cpd,Rin2,Vcan,Peli1,Sod2,Bcl2a1b,Nfkbia,Aoah,Trem1,Ldlr,Rbms1,Notch2,Acsl1,Ier3,Ell2,Dram1,Pla2g7,Oas1a,Marco,Tnfrsf1b,S100a8,Irak3,Plagl2,Cd14,Slco3a1,Fgr,Upp1,Hif1a,Bcl2a1d,Egr2,Csf3r,Bcl2a1a,Cxcl1,Fpr1,Oas1g,Hmox1,Rnf19b,Bst1,Btg2,Ext1,Map4k4,Tuba4a,Dusp6,Nampt,Slc31a2,Ccr1 |
| 1.851e-16 | -36.23 | GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 442 | 89 | 15632 | 1249 |
Rapgef2,Dusp6,Fzd5,Map2k1,Pdgfrb,Kitl,Irak2,Il1b,Htr2b,Tlr3,Crkl,Ripk2,Adora2b,Trib3,Map3k8,Hspa2,Tnf,Traf2,Rgs3,Pdgfc,Tnfaip3,Irak3,Cd74,Tab2,Ikbkg,Cav1,Jak2,Dusp16,Cdkn1a,Tlr9,Trib1,Lpar1,Lyn,Dusp2,S1pr2,Pde5a,Dusp4,Gadd45g,Gadd45b,Eif2ak2,Syk,Dnaja1,Spred1,Dusp14,Cdkn2d,Kat2b,Cdk5r1,Mul1,Pdgfb,Tnfsf15,Pik3r6,Thbs1,Ptprj,Dusp5,Uchl1,Pim1,Fpr1,Casp3,Dbnl,Dusp8,Ccnd1,Dusp1,Src,Rgs14,Cd40,Nod1,Bmp2,Daxx,Mdfic,Malt1,Hhex,Sirt1,Rasgrp1,Igf1r,Prkar2b,Aida,Acsl1,Edn1,Spry2,Nod2,Map3k6,Flt1,Pik3r5,Psmd10,Htr2a,Atp2b4,Mapkapk2,Tlr6,Ccnd2 |
| 1.907e-16 | -36.20 | GSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_UP | MSigDB lists | GSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_UP | 153 | 47 | 15632 | 1249 |
Arl5b,Phlda1,Adora2a,Nfkbid,Cd274,Ppp2r2a,Zc3h12a,Smox,Usp31,Nr4a3,Pim1,Adora2b,Cish,Dusp8,Slc15a3,Nr3c1,Usp53,Zswim4,Ankrd17,Cd83,Tnfaip3,Relb,Csrnp1,Mxd1,Plk3,Traf1,Icam1,Cd69,Nfkb1,Rabgef1,Birc3,Abtb2,Sik3,Tmem67,Dnajb2,Ell2,Mafg,Odc1,Dusp2,Dusp4,Cpd,Itgav,Bcl2l11,Gadd45b,Dusp14,Nfkbiz,Etv3 |
| 1.917e-16 | -36.19 | GSE24726_WT_VS_E2_2_KO_PDC_DN | MSigDB lists | GSE24726_WT_VS_E2_2_KO_PDC_DN | 183 | 52 | 15632 | 1249 |
Dram1,Ptk2,Il13ra1,Dnajb2,Cflar,Clec4n,Rnf19a,Met,Egln3,Atxn7l1,Ubash3b,Ciapin1,Egr1,Klf7,Ahr,Mrpl52,Aoah,Pik3r5,Parp9,Pdpn,Slc44a1,Smox,Parp3,Hcar2,Cmklr1,Acsl5,Nfkb2,Tor1aip1,Samsn1,Irf7,Slc13a3,Plek,Slc31a2,Spint2,Gpr132,Nrp2,H2-Aa,Gbgt1,Usp18,Isg15,Psmb10,Traf1,Hvcn1,Gbp2,Ube2f,Traf2,Acpp,P4ha2,Stk40,Cebpd,Stat3,Egr2 |
| 1.979e-16 | -36.16 | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_UP | MSigDB lists | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_UP | 177 | 51 | 15632 | 1249 |
Nfkbia,Gsdmd,Mllt6,Pcx,Cpd,Trim13,Gmppb,Tmem176b,Pgs1,Col18a1,F10,Birc3,Rnf14,Tmem176a,Procr,Srxn1,Odc1,Tlr2,Ebi3,Il13ra1,Trem1,Agpat4,Hsd17b7,Ust,Fam20c,P4ha2,Dusp1,Psmb10,Malt1,Rgs3,Ube2f,Tal2,Samsn1,Cd274,Fubp1,Pik3r6,Junb,Hsd17b12,Snx10,Bst1,Tbc1d13,Maff,Nrp2,Antxr1,Phlda1,Tgfbi,Stip1,Cxcl1,Il1rn,Pcdh7,Ikbke |
| 1.979e-16 | -36.16 | GSE3039_NKT_CELL_VS_B2_BCELL_DN | MSigDB lists | GSE3039_NKT_CELL_VS_B2_BCELL_DN | 177 | 51 | 15632 | 1249 |
Rab19,Sphk1,Csrnp1,Tnfaip3,Klhl25,Slc2a1,Usp53,Slc16a3,Mafk,B3gnt5,Cish,Slc15a3,Grina,Trib3,Ptgs2,Nr4a3,Smox,Pcgf5,Ldha,Il1b,Hcar2,Dusp6,Gch1,Cxcl2,Maff,Irs2,Tpi1,Klf7,Sdc4,Trp53i11,Cd80,Ets2,Nlrc5,Sod2,Dusp4,Cxcl14,Edn1,Tlr2,Uaca,Dusp16,Trem1,Cdkn1a,Nfil3,Pmepa1,Rbms1,Ccl4,Cav1,Ccrl2,Csf1,Procr,Atxn7l1 |
| 2.182e-16 | -36.06 | SMIRNOV_RESPONSE_TO_IR_6HR_DN | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_6HR_DN | 109 | 39 | 15632 | 1249 |
Cdk5r1,Tpx2,Hhex,Itga4,Ier2,Aim2,Egr1,Tle3,Traf5,Gpr18,Tnf,Cenpe,Klf6,Slc16a3,Ccng2,D1Ertd622e,Bnip3,Dusp2,Myc,Trib1,Egr3,Cd55,Oas1g,Rnaset2b,Rgs1,Ldlr,Ccl4,Rnaset2a,Klf2,Lcp2,Ccr1,P4ha1,Oas1a,Kctd12,Egln3,Cd69,Maff,Hk2,Zfp36 |
| 2.246e-16 | -36.03 | POOLA_INVASIVE_BREAST_CANCER_UP | MSigDB lists | POOLA_INVASIVE_BREAST_CANCER_UP | 248 | 62 | 15632 | 1249 |
Irf8,Cd69,Stat4,Pla2g7,Trip13,Isg20,Mmp9,Tnfsf4,Hcls1,Ccl4,Rhof,Bcl2a1b,Bcl2l11,Plac8,Vcan,Chst11,Ctsc,Ikzf1,Tpx2,Pttg1,Lrp8,Serpine1,Lcp2,Hopx,Samsn1,Cd86,Gdf15,Plek,Ccr1,Fcgr4,Mmp13,Inhba,Slc7a5,H2-Aa,Cxcl10,Il2rg,Il18,Slamf8,Abcc4,Tfec,Plaur,Bcl2a1a,Vcam1,Gpsm2,Cd40,Cst7,Sp140,Slc16a3,Apobec3,Bcl2a1d,Rsad2,Tnc,Sell,Traf1,Calcrl,Cd74,Kmo,Ch25h,Itga4,Aim2,Cd38,Sla |
| 2.280e-16 | -36.02 | NAGASHIMA_EGF_SIGNALING_UP | MSigDB lists | NAGASHIMA_EGF_SIGNALING_UP | 53 | 27 | 15632 | 1249 |
Trib1,Nr4a3,Ier3,Egr3,Kdm6b,Dusp5,Maff,Zfp36,Phlda1,Gem,Fosb,Junb,Atf3,Ier2,Egr1,Lif,Edn1,Dusp2,Egr2,Myc,Fos,Ets2,Jun,Tiparp,Dusp1,Nr4a1,Klf6 |
| 2.471e-16 | -35.94 | GSE17721_LPS_VS_CPG_8H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_8H_BMDC_UP | 184 | 52 | 15632 | 1249 |
Acpp,Hspa2,Ythdf1,Sat1,Cish,Pde1b,Cd180,Upp1,Slco3a1,Prdm1,Crim1,Rab3ip,Prpf38a,Myd88,Cd274,Tap2,Pdgfrb,Wars,Cxcl10,Keap1,Sec24b,Dek,Ncoa5,Edn1,Ctsc,Parp14,Katna1,Il6,Slc44a1,Kat2b,Tpx2,Tlr6,Rbl1,Zbp1,Slamf7,Gng11,Ifit3,Plekha2,Casp4,Ankib1,Ccne1,Csf1,Timeless,Ep400,Lpar1,Ifit3b,Azi2,Ifi35,Dusp16,Actb,Cd300lf,Ccl4 |
| 2.471e-16 | -35.94 | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_DN | 184 | 52 | 15632 | 1249 |
Upp1,Stat2,Arg2,Fabp3,Stat5a,Csf3r,Cd40,Ly75,Prdx5,Cebpd,Ptprj,Smc5,Cxcl10,Fpr1,Il1rn,Jarid2,Pde4b,Gch1,Serpine1,Icosl,Ube2l6,Wars,Tbc1d13,Maff,Atf3,Mapkapk2,Irs2,Gmppb,Prdx1,Olr1,Ets2,Fcgr2b,Tor1aip2,Dusp2,Katna1,Stard5,Cpd,Egr3,Mtmr14,Mtdh,Dtx2,Ell2,Oasl1,Denr,Ier3,Notch2,Frmd6,Marco,P2ry2,Atxn7l1,Plscr1,Rnf19a |
| 2.471e-16 | -35.94 | GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_DN | 184 | 52 | 15632 | 1249 |
Dtwd1,Stxbp1,Ifnb1,Tor1aip2,Igsf6,Stard5,Cited2,Ets2,Flt1,Rab32,Bcl2l11,Sbds,Dusp16,Frmd6,Clcf1,Endod1,Mtmr14,Socs3,Rnf19a,Syne2,Plscr1,Marco,Sema3c,Cav1,Casp4,Lmo4,Tnfrsf1b,Stau1,Mdfic,Olfml3,Tnfrsf8,Arg2,Marcksl1,Klhl25,Hspa1a,Csf3r,Ehd1,Phldb1,Spryd7,Tfec,Il1rn,Slfn3,Ralgds,Clec5a,Osgin2,Smc5,Ppp2r3a,Maff,Stxbp3,Samsn1,Slfn4,Pde4b |
| 2.535e-16 | -35.91 | positive regulation of MAPK cascade | biological process | GO:0043410 | 525 | 90 | 20694 | 1406 |
Tlr2,Cysltr2,Sphk1,Crkl,Jak2,Tlr6,Marco,Scimp,Notch1,Zc3h12a,Ripk2,Lpar1,Mul1,Pdgfb,Lif,Flt1,Traf2,Fpr2,Ptprj,Map2k1,Map4k4,Src,Gcnt2,Spry2,Nod2,Edn1,Sema4c,Ccl9,Pde5a,Ccl8,Htr2a,Gadd45g,Fzd5,Pdgfrb,Map3k8,Glipr2,Eif2ak2,Ccl7,Map2k4,Tlr9,Adrb2,Ccl2,Osm,Prkce,Tlr3,Htr2b,Il1b,Pik3r6,Mlkl,Ccl22,Pdgfc,Cflar,Ksr1,Mid1,Il6,Bmp2,Rapgef2,Thbs1,Notch2,Nod1,Ccl5,Icam1,Map3k6,Cd40,Igf1r,Nox1,Cd74,C3,Il1rn,Gadd45b,Gdf15,Jun,Kitl,Mapkbp1,Tnf,Cx3cl1,Il1a,Ccl3,Mdfic,Syk,Kdr,Ccl4,Ccr1,Ccl12,Rasgrp1,Fcgr2b,Pik3r5,Met,Myd88,Angpt1 |
| 2.563e-16 | -35.90 | GSE22589_SIV_VS_HIV_AND_SIV_INFECTED_DC_UP | MSigDB lists | GSE22589_SIV_VS_HIV_AND_SIV_INFECTED_DC_UP | 178 | 51 | 15632 | 1249 |
Mapkapk2,Rtp4,Clec4e,F10,Col4a2,Dnase1l3,Enpp4,Rnf114,Nfkbia,Ppp2r5a,Parp9,Tmod3,Stat1,Oasl1,Ifit3b,Slc25a22,Irf1,Rnf14,Tor3a,Ifit3,Ccrl2,Csrnp1,Mxd1,Ch25h,Socs1,Ddx58,Stat2,Usp18,Myd88,Nod1,Tnfaip3,Ifit2,Ehd1,Acpp,Psmb9,Setdb2,Batf2,Mlkl,Dhx58,Treml2,Ptafr,Cmpk2,Ccl5,4933430I17Rik,Irf7,Lcp2,Col11a2,Stxbp3,Tlr1,Sap30,Tbc1d13 |
| 2.563e-16 | -35.90 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN | 178 | 51 | 15632 | 1249 |
Zeb1,Plscr1,Nfkb1,Ppp1r15b,Jak2,Cd300lf,Map2k4,Filip1l,Itpkc,Cd200,4932438A13Rik,Ifrd1,Peli1,Nlrc5,Atp11b,Adar,Slc16a1,Slamf7,Tmtc2,Pgs1,Atf3,Mapkapk2,Nfkbid,Oas2,Slc7a5,Asns,Ppp1r15a,Tap2,Lcp2,Vps54,Mthfd1l,Junb,Plek,Zhx2,Clic4,Ttc39b,Tapbpl,Nr4a3,Larp1,Usp31,Treml2,Stk40,Cish,Arhgef3,Mgat1,Relb,Gys1,Lipg,Calcrl,Icam1,Mthfr |
| 2.613e-16 | -35.88 | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_UP | MSigDB lists | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_UP | 160 | 48 | 15632 | 1249 |
Cd38,Ifih1,Mxd1,Prdm1,Aim2,Fgl2,Mlkl,Carhsp1,Pnp2,Slc15a3,Phf11b,Insl6,Il1b,Cmklr1,Clec4d,Cxcl10,Ttc39b,Bst1,Sap30,Hopx,Snx10,Ifit1bl2,Myadm,Gch1,Phf11c,Pilra,Phf11a,Pttg1,Rtp4,Chst11,Fcgr2b,Nfkbia,Cx3cr1,Ifit1bl1,Trem1,Rgs1,Ccl4,Odc1,Phf11d,Ier3,Tnfsf4,Ell2,Pla2g7,Il18rap,Isg20,Cysltr2,Plscr1,Gem |
| 2.807e-16 | -35.81 | regulation of cellular response to stress | biological process | GO:0080135 | 665 | 105 | 20694 | 1406 |
Scarf1,Akt3,Hk3,Zc3h12a,Dek,Tlr6,Sphk1,Map2k1,Map4k4,Ripk2,Parp9,Mul1,Arg2,Traf2,Spred1,Usp25,Ppp4r2,Fzd5,Ptpn2,Gadd45g,Dtx3l,Myc,Fas,Nupr1,Radx,Nod2,Sema4c,Edn1,Dnaja1,Glrx,Map2k4,Ppp1r15b,Ezr,Il10,Tlr9,Phlpp1,Eif2ak2,Pnpt1,Eef1e1,Hmga2,Il1b,Pmaip1,Grina,Sirt1,Ier3,Mlkl,Mdm2,Psmd10,Spire1,Nr4a3,Kremen1,Slc7a11,Ncoa7,Lyn,Ikbkg,Tlr3,Bmp2,Plscr1,Fbxo4,Cd34,Hsph1,Plk2,Timeless,Mid1,Ptgs2,Dusp1,Hif1a,Atm,Gadd45b,Spred3,Cgas,Txn1,Il1rn,Cd74,Parp3,Ppp1r15a,Aida,Bcl6,Nod1,Cdkn2d,Tmem67,Fignl2,Nox1,Rbl1,Igf1r,Fut8,Kmt5a,Fcgr2b,Eya4,Rasgrp1,Gch1,Nampt,Pml,Met,Myd88,Prdx1,Nck1,Bfar,Il1a,Mdfic,Mapkbp1,Tnf,Fzd1,Sod2,Syk |
| 2.813e-16 | -35.81 | GO_INTERFERON_GAMMA_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_INTERFERON_GAMMA_MEDIATED_SIGNALING_PATHWAY | 66 | 30 | 15632 | 1249 |
Mid1,Irf4,Oas3,H2-Q6,H2-Q4,Gbp2,Hck,Fcgr1,Ciita,Trim12c,Icam1,Pml,Irf2,H2-Q7,Oas2,Oas1a,H2-Aa,Trim26,Trim21,Irf7,Irf8,H2-Eb1,Jak2,Vcam1,Ptafr,Irf1,Stat1,Oas1g,Oasl1,H2-Ab1 |
| 3.177e-16 | -35.69 | JISON_SICKLE_CELL_DISEASE_UP | MSigDB lists | JISON_SICKLE_CELL_DISEASE_UP | 185 | 52 | 15632 | 1249 |
Atf3,Il15,Trp53i11,Prdx1,Gng11,Fcgr1,Tap1,Gadd45b,H2-Q4,Ifit1bl1,Cox17,Ptk2,Casp7,Ifi35,Oasl1,Stat1,Ifit3b,Jak2,Cdkn1a,Vrk2,Psmb8,Ifit3,Marco,St3gal5,Psme2,Ccrl2,Tdrd7,H2-Q7,Gbp2,Ifit2,Axl,Txnrd1,H2-Q6,Timp1,Psmb9,Ifi44,Rnf24,Nfkbie,Rsad2,H2-Ab1,Smox,Hmox1,Cxcl10,Clic4,Tfec,Snn,Plek,Txn1,Ifit1bl2,Rgl1,Atp6v1d,Ube2l6 |
| 3.242e-16 | -35.67 | immune response-regulating signaling pathway | biological process | GO:0002764 | 221 | 53 | 20694 | 1406 |
Icosl,Cd38,Spn,Cacnb3,Cd86,Trim12c,Fpr2,Klrk1,Tifa,Ripk2,Irgm2,Bcl2a1d,Zc3h12a,Irak2,Cd300lf,Lgals9,Mapkapk2,Tlr6,Lcp2,Tlr3,Crkl,Nfkbiz,Ddx58,Clec4e,Nr4a3,Prkce,Clec4d,Tlr2,Themis2,Lyn,Tnip1,Myd88,Fcgr1,Tlr9,Nfkbia,Fcgr2b,Cmklr1,Syk,Tnf,Fcgr4,Malt1,Cd14,Fpr1,Rnf31,Pde4b,Irak3,Tlr1,Ifih1,Cd40,Dennd1b,Tnip3,Nod2,Nfkbid |
| 3.315e-16 | -35.64 | G_IRG | prosite domains | PS51716 | 16 | 15 | 13278 | 1037 |
Irgm2,Irgm1,Gm12185,Irgq,Ifi47,Iigp1,9930111J21Rik1,Tgtp1,Igtp,Gm5431,F830016B08Rik,Gm12250,Gm4841,9930111J21Rik2,Gm4951 |
| 3.357e-16 | -35.63 | GERY_CEBP_TARGETS | MSigDB lists | GERY_CEBP_TARGETS | 132 | 43 | 15632 | 1249 |
Sat1,Mafk,Hsph1,Dusp1,Ifi213,Ifi209,Ifi205,Hspa1a,Ier2,Ifi208,Btg2,Gch1,Junb,Ppp1r15a,Slfn4,Serpinb2,Plat,Slfn3,Glrx,Plaur,Hmox1,Hp,Trib3,Pim1,Gadd45g,Ifrd1,Vcan,Gadd45b,Fos,Ifi207,Atf3,Ifi214,Prnp,Ifi211,Procr,Ifi203,S100a8,Mndal,Lcn2,Dnajb2,C3,Acsl1,Ifi204 |
| 3.453e-16 | -35.60 | GO_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | MSigDB lists | GO_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 167 | 49 | 15632 | 1249 |
Tlr6,Nek6,Mul1,Trim13,Zc3hav1,Peli1,Prkce,Nod2,Pim2,Mtdh,Tlr9,Tlr2,Lpar1,Cflar,Ikbkg,Rnf31,Birc3,Clec4n,Casp8,Tnfsf14,Rel,Malt1,Sphk1,Trim12c,Tab2,Il1a,Nod1,Traf5,Myd88,Rhoc,Casp1,Tnf,Cd40,Ankrd17,Birc2,Traf2,Hmox1,Traf3ip2,Ripk2,Tlr3,Il18,Il12b,Ptgs2,Ikbke,Tnfsf10,Htr2b,Il1b,Gja1,Plk2 |
| 3.453e-16 | -35.60 | GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_DN | MSigDB lists | GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_DN | 167 | 49 | 15632 | 1249 |
Plat,Zhx2,Il15ra,Dusp5,Serpinb9,Il12b,Ptgs2,Gpr132,Ppp2r3a,AA467197,Nfkbid,Map4k4,Gch1,Pde4b,Igsf8,Med21,Lad1,Mapkbp1,Relb,Rab3ip,Csrnp1,Prrg4,Lrch3,Tpst1,Swap70,Ldlr,Ppp2r1b,Tnfaip2,Fscn1,Clcf1,Cdkn1a,Ptgir,Cd200,Il13ra1,Ebi3,Sema4c,Hmgcs1,Irf1,Med13,Isg20,Cnn3,Abtb2,Zbtb5,Optn,Sod2,Gramd1a,Gadd45b,Casz1,Trip10 |
| 3.942e-16 | -35.47 | MODULE_436 | MSigDB lists | MODULE_436 | 116 | 40 | 15632 | 1249 |
Samsn1,Cd86,Ifit1bl2,Rnf31,Oas1a,Csf3,Kctd12,Pou2f2,Ube2l6,H2-Aa,Rcsd1,Fpr1,H2-Ab1,Ifi35,Cd200,Oas1g,Stat1,Trem1,Plcl2,Adam19,Tnfsf10,Thbs1,H2-Q6,Oas3,H2-Q4,Nlrc5,Ifit1bl1,Mecp2,Sdc2,Cebpd,Rsad2,Parp14,Peli1,Cd74,Isg15,H2-Q7,Hvcn1,Tap1,Gbp2,Cd14 |
| 4.076e-16 | -35.44 | GSE29618_MONOCYTE_VS_PDC_UP | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_UP | 186 | 52 | 15632 | 1249 |
Tnfaip2,Trem1,Nfil3,Trib1,Acsl1,Ier3,Rab20,Tlr2,Pla2g7,Tnfrsf1b,Marco,Pilra,Il15,Tspo,Egr1,Irs2,Nlrp3,Peli1,Nod2,Rin2,Rab32,Aoah,Bcl2a1b,Sod2,Il1rn,Bcl2a1a,Rnf19b,Hmox1,Cdc42ep4,Fpr1,Bst1,Hk2,Nampt,Slc31a2,Csrp1,Cd86,Cd14,Sla,Irak3,Gbp2,Hck,Ier2,Upp1,Hif1a,Slco3a1,Fgr,Fgl2,Bcl2a1d,Casp1,Timp1,Bcl6,P2ry13 |
| 4.076e-16 | -35.44 | GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_DN | MSigDB lists | GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_DN | 186 | 52 | 15632 | 1249 |
Ier3,Ifit3b,Ell2,Oasl1,Ccl4,Rgs1,Adam19,Gna15,Tnfsf14,Ifit3,Ltbp2,Tnfrsf1b,Nfkb1,Htra1,Mapkapk2,Prpf4,Tmem184b,Hmga1,Sqstm1,Slc7a11,Ifit1bl1,Nqo1,Dusp2,Tgfbi,Il1b,Htr2b,Inpp1,Serpinb2,Thbs1,Serpine1,Fubp1,Ppp1r15a,Flrt2,Map4k4,Ifit1bl2,Slc7a8,Vasp,Dgka,Cxcl2,Snx2,Ddit4,Traf1,Cd180,Timp1,Txnrd1,Slc16a3,Phldb1,Ifit2,Dock10,Ifi44,Pnp2,Tnfsf8 |
| 4.274e-16 | -35.39 | GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP | 180 | 51 | 15632 | 1249 |
Denr,Rab20,Arf4,Tax1bp1,Tnip1,Birc3,Zeb1,Nfkbib,Atf3,Irs2,Pim3,Klf7,Nr4a1,Gadd45b,Bcl2l11,Sqstm1,Pik3r5,Rhof,Ptpn2,Ets2,Mllt6,St3gal1,Fndc3a,4930453N24Rik,Nr4a3,Map4k4,Ppp1r15a,Pdgfb,Caml,Slc7a5,Maff,Slc30a4,Csrnp1,Il1a,Icam1,Relb,Tnfaip3,Src,Klf6,Dusp1,Phldb1,Arid5a,Swap70,Arhgef3,Cd40,Hspa1a,Egr2,Rnf24,Ccdc86,Tlk2,Mafk |
| 4.520e-16 | -35.33 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_UP | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_UP | 162 | 48 | 15632 | 1249 |
Zbp1,Cd80,Pfkfb3,Samhd1,Tpx2,Gpr141,Fcgr2b,Rapgef5,Cenpe,Nlrc5,Cd300lf,Notch2,C3,Mmp9,Ell2,Stat1,Tlr9,Slpi,Trip13,Tifa,Rap1gap2,Il18rap,Pou2f2,Smpdl3b,Gem,Hdc,Lcn2,Casp4,Irf8,Cd83,Nod1,Gda,Notch1,Pml,Mxd1,Fgr,Slc15a3,Arhgap26,Fgl2,Osbpl3,Cxcl10,Fpr1,Ptafr,Tgfbi,Phlpp2,Ccl5,Cd274,Asns |
| 4.666e-16 | -35.30 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | biological process | GO:0002822 | 187 | 48 | 20694 | 1406 |
Rsad2,Tnf,H2-Q6,Arid5a,Tnfsf4,Fcgr2b,Fcgr1,Il27,Irf1,Nod2,Nfkbid,Ifnb1,H2-Q7,Tap2,Cd40,Parp3,C3,Cd55,Il12b,Nectin2,Bcl6,Fzd5,Malt1,Hlx,Ripk2,Il6,Traf2,Pvr,Spn,H2-Ab1,H2-M2,Tnfaip3,Il4ra,H2-T22,Il12rb1,Ripk3,Clcf1,H2-Q4,Nfkbiz,H2-T10,Lgals9,Il1b,Cd274,Nlrp3,H2-T24,Zc3h12a,Tnfrsf1b,Il18 |
| 4.889e-16 | -35.25 | regulation of lymphocyte proliferation | biological process | GO:0050670 | 223 | 53 | 20694 | 1406 |
Cd274,Il1b,Lgals9,Il18,Itgal,Tnfrsf1b,Ripk3,Clcf1,Ahr,Il12rb1,Tarm1,Tnfrsf14,Lyn,Casp3,Cd86,Icosl,Peli1,H2-Ab1,Tnfsf9,Prnp,Spn,Cd38,Ripk2,Arg2,Cd80,Atm,Il6,Il12b,Cd74,Ccdc88b,Bcl6,Pde5a,Il15,Ccl5,Irs2,Vcam1,Cd40,Tnfsf4,Sdc4,Fcgr2b,Il10,Cdkn1a,Myd88,Irf1,Tlr9,Prdm1,Il27,Nck1,Slfn1,Stat5a,Bst1,H2-Aa,Syk |
| 4.919e-16 | -35.25 | MODULE_345 | MSigDB lists | MODULE_345 | 106 | 38 | 15632 | 1249 |
Cd14,Hvcn1,Gbp2,Tap1,H2-Q7,Cd74,Isg15,Sell,Parp14,Peli1,Ifi44,Sdc2,Mecp2,Rsad2,Cebpd,H2-Q4,Ifit1bl1,H2-Q6,Oas3,Adam19,Thbs1,Tnfsf10,Trem1,Ifi35,H2-Ab1,Stat1,Oas1g,Fpr1,Ube2l6,H2-Aa,Csf3,Oas1a,Pou2f2,Kctd12,Ifit1bl2,Rnf31,Cd86,Samsn1 |
| 4.964e-16 | -35.24 | positive regulation of hydrolase activity | biological process | GO:0051345 | 680 | 106 | 20694 | 1406 |
Psme2,Cflar,Abr,Plscr1,Tank,Plek,Rapgef2,Bmp2,Rgs3,F11r,Htr2b,Asap3,Tbc1d13,Lyn,Cav1,Psme1,Sirt1,Arf4,Ccl22,Pmaip1,Ccl4,Ric1,Syk,Tnf,Cx3cl1,Ccl3,Jun,Fam162a,Arhgap26,Tnfsf10,Ift57,Ccl12,Rasgrp1,Casp8,Pml,Dnajb4,Cd40,Tagap,Ccl5,Icam1,Nod1,Malt1,Ppp1r15a,Tor1aip2,Mmp25,Tbc1d1,Agrn,Mefv,Flt1,Ptafr,Dnaja2,Ripk2,Mul1,Lpar1,Tnfsf15,Cdc42ep2,Bcl2l11,Stat3,Casp4,Map4k4,Dock10,Map2k1,Casp1,Jak2,Stat1,Nlrc4,Uaca,Rin2,Rap1gap2,Crkl,Cd200,Ripk3,Cycs,Ahsa1,Ranbp2,Nlrp3,Rgs14,Zc3hav1,Sele,Rgs1,Aim2,Ccl7,Ccl2,Apaf1,Adrb2,Ppp1r15b,S100a8,Sipa1l1,Elmod2,Tor1aip1,Hspa2,Antxr1,Dnaja1,Pkp4,Dennd1b,Fas,Dock4,Adap2,Dnajb2,Pdgfrb,Myc,Ccl8,Htr2a,Ccl9,Rhoc,Nr1h3 |
| 5.188e-16 | -35.20 | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | MSigDB lists | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | 232 | 59 | 15632 | 1249 |
Bcl2a1b,Tagln,Trip10,Cyfip1,Tspan3,Ctsc,Rin2,Vcan,Ifi214,Ccnd2,Col4a2,Me1,Ifi207,Tnfrsf1b,Hk1,Ltbp2,Lmo4,Mndal,Gem,Akt3,Procr,Ifi211,Ifi203,Pim2,Ier3,Lyn,Mthfd2,Irf1,Ifi204,Hcls1,Gypc,Ifi213,Tcf4,Ifi209,Slc2a1,Ifi205,Pnp2,Bcl2a1d,Fgl2,Cd74,Hif1a,Sla,Traf5,Ccl5,Tuba4a,Ifi208,Slc7a5,Dgka,Dusp5,H2-Ab1,Il2rg,Nsmaf,Lox,Ikbke,Ralgds,Bcl2a1a,Pgk1,Plaur,Il15ra |
| 5.219e-16 | -35.19 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_DN | 187 | 52 | 15632 | 1249 |
Samd9l,Spry2,Irgm2,Mmp14,Ppp2r5a,Rnf114,Sod2,Ass1,Samhd1,Col4a2,Cdc42ep2,Sass6,Evl,Stat4,Ccrl2,Eef1e1,Alas1,Pdss1,Plscr1,Ogfr,Jak2,Cd300lf,Tmem123,Mlkl,C1ra,Cp,Ly75,Rbbp8,Src,Tnf,Pbx1,Sla,Upp1,Gbp3,Arg2,Nfkbid,Inhba,Spint2,Flrt2,Lgals9,Asns,Tap2,Junb,Snx10,Plaur,Pf4,Dek,Acsl5,Thbs1,Chic2,Fpr1,Larp1 |
| 5.721e-16 | -35.10 | GSE360_CTRL_VS_T_GONDII_DC_DN | MSigDB lists | GSE360_CTRL_VS_T_GONDII_DC_DN | 175 | 50 | 15632 | 1249 |
Dusp1,Cp,Ly75,Sat1,Cebpd,Psma6,Rsad2,Traf1,Cd83,Traf5,Tnfaip3,Relb,Map2k1,Nrp2,Stx11,Rapgef2,Dusp5,Ptger4,St3gal1,Nr4a3,Ak4,Sec24a,Nfkb2,Il15ra,Sod2,Agrn,Nfkbia,Gadd45b,Trip10,Dusp4,Tra2a,Ifrd1,Col4a2,Zbtb5,Tap1,Klf7,Nfkb1,Ifit3,Psme2,Isg20,Il13ra1,Cd200,Socs3,Ifi35,Adrb2,Ifit3b,Trib1,Rgs1,Tnfaip2,Cflar |
| 5.993e-16 | -35.05 | GO_REGULATION_OF_RESPONSE_TO_WOUNDING | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_WOUNDING | 374 | 79 | 15632 | 1249 |
Tnip1,Ccl4,Jak2,Lyn,Mefv,Adrb2,Tlr2,Socs3,C3,Tnfsf4,Tlr9,Smpdl3b,Pla2g7,Rictor,Casp4,Nos2,Cav1,Il10,Tnfrsf1b,Nfkb1,Ednrb,Birc3,S100a8,Rabgef1,Enpp4,Il15,Plau,Cd34,Nlrp3,Nr1h3,Cx3cl1,Ubash3b,Abr,Scarf1,Nod2,Il6,Ccl2,Prkce,Pla2g4a,Edn1,Zyx,Ptpn2,Ccl12,Syk,Cx3cr1,Spn,Il1b,Plaur,Plat,Serpinb2,Thbs1,Il18,Il12b,Ptgs2,Adora2b,Zc3h12a,Cd55,Tlr3,Ptger4,Pdgfb,Serpine1,Slc7a2,Map2k1,Osm,Hopx,Ccl5,Gja1,Plek,Ccl3,Tnfaip3,Hck,Myd88,Calcrl,Psma6,Sele,Birc2,Bcl6,Casp1,Tnf |
| 6.306e-16 | -35.00 | GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | MSigDB lists | GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 869 | 139 | 15632 | 1249 |
Socs1,Sell,Sphk1,Hif1a,Ddx58,Icam1,Mthfr,Notch1,Daxx,Bmp2,Cd83,Rbbp8,Birc2,P2ry12,Psmb9,Casp1,Dusp1,Src,Ccnd1,Acvr1,Mdm2,Casp3,Nr3c1,Lox,Cxcl10,Ptafr,Serpinb9,Pim1,Ptgs2,Zc3h12a,Ldha,Ptger4,Thbs1,Il1rn,Klf2,Junb,Nampt,Ifit1bl2,Ifna6,Pdgfb,Btg2,Il4ra,Egr1,Lrp8,Atp2b4,Htr2a,Adar,Plau,Ifna1,Tiparp,Jun,Tet2,Fos,Msr1,Slc7a11,Ccl12,Nfkbia,Ezr,Ifit1bl1,Nqo1,Sdc2,Prkce,Il6,Peli1,Edn1,Adrb2,Acsl1,Socs3,Stat1,Prkar2b,Ptch1,P2ry2,Il10,Ccne1,Irak3,Ifna2,Cd38,P2ry13,Homer1,Tnf,Klf6,Mecp2,Errfi1,Stat3,Tnc,Nr4a3,Il18,Ripk2,Hmox1,Tlr3,Htr2b,Keap1,Ptges,Il1b,Ppp2r2a,Vcam1,Pdgfrb,Fosb,Ppp1r15a,Asns,Dusp6,Ccl5,Pde4b,Fzd1,Mmp13,Rapgef2,Inhba,Nr1h3,Mul1,Sdc1,Cdkn2d,Fas,Zc3hav1,Ahr,Tspo,Slc16a1,Il15,Cited2,Dnaja1,Ass1,Nr4a1,Eif2ak2,Ifnb1,Ifna5,Mmp14,Pla2g4a,Lyn,C3,Hmgcs1,Cdkn1a,Pmepa1,Jak2,Casp8,Cav1,Ednrb,Nfkb1,Rnf14,Med13,Slc9a1 |
| 6.603e-16 | -34.95 | CHICAS_RB1_TARGETS_SENESCENT | MSigDB lists | CHICAS_RB1_TARGETS_SENESCENT | 498 | 95 | 15632 | 1249 |
Tnfaip3,Phgdh,Cers6,Slc25a37,Lrp11,Vcam1,Cxcl1,Ripk2,St3gal1,Frmd4a,Mcm6,Trib3,Ddit4,Fzd1,AA467197,Cxcl2,Inhba,Serpine1,Cacybp,Cd274,Ddx60,Gclm,Mllt6,Sod2,Psip1,Bcl2a1b,Gbp2b,Cd82,Vrk2,Mmp9,C3,Egr3,Ifit3b,Odc1,Psme2,Tifa,Isg20,Cnn3,Zeb1,Spen,Pou2f2,Kctd12,Mmd,Jdp2,Gem,Mcmbp,Lif,Dtx3l,Isg15,Il1a,Fut8,Bcl2a1d,Dync1h1,Rbbp8,Acpp,Bcl2a1a,Dek,Dio2,Dcbld2,Dusp5,Cxcl10,Slamf8,Slc43a3,Ptgs2,Phlda1,Tnfsf15,Ube2l6,Csf3,Gch1,Nampt,Jarid2,Slc7a2,Rnaset2a,Samhd1,Egr1,Nfkbiz,Plagl1,Il6,Bbx,Peli1,Flt1,Rhof,Jun,Rnaset2b,Trem1,Dck,Gpd2,Plscr1,Hat1,Cd69,Ccne1,Eno2,Birc3,Psmb8,Ifit3 |
| 6.605e-16 | -34.95 | LENAOUR_DENDRITIC_CELL_MATURATION_DN | MSigDB lists | LENAOUR_DENDRITIC_CELL_MATURATION_DN | 123 | 41 | 15632 | 1249 |
Sod2,Tnf,Nfkbia,Itpr1,Gsr,Fgl2,Sdc2,Mapkapk2,Marcksl1,Isg15,Cd180,Cd14,Tal2,Olr1,Me1,Tuba4a,Tnfrsf1b,Brd2,Dusp6,S100a8,Nampt,Irf7,Itgal,Ampd3,Plscr1,Htra1,Pdlim7,Tlr1,Btg2,Cxcl2,Bst1,Mmp9,C3,Rtn1,Ptafr,Ier3,Il2rg,Cxcl1,Pf4,Il1b,Plaur |
| 6.632e-16 | -34.95 | cell surface | cellular component | GO:0009986 | 941 | 132 | 20747 | 1409 |
Prnp,H2-Ab1,Cd69,Tlr3,Nectin2,Il1a,Gsr,Mmp25,Hilpda,Spn,B430306N03Rik,Cd274,Cd14,Itgal,Icam1,Tmem123,Eno2,Agrn,Ciita,Slco3a1,Pvr,Tnfrsf14,Plau,Hspa2,Cav1,Eno1,Acvr1b,H2-T10,Fzd1,Cx3cl1,H2-M2,Nod2,Vcan,Pdgfc,Itga5,H2-Q7,Slamf7,Cd74,H2-Q4,Cd200,Ccr3,Clic4,H2-Aa,Ldlr,Cd86,Ly6c2,H2-T24,Cx3cr1,Il15,Ptprj,Clec5a,H2-Q6,Sdc2,Notch1,Slc7a11,Raet1e,H2-T22,Adora2b,Vasn,Il12rb1,Ebi3,Cd38,Adam19,P2ry12,Itgb8,Cxcl10,Plat,Kdr,Tlr2,Cacna1d,Cd83,Fcgr4,Il6,Icosl,Clec2d,Treml4,Pdpn,Bmp2,Nlgn2,Thbs1,Fas,Xcr1,Il15ra,Fcgr1,Cd34,Sdc1,Treml2,Vcam1,Acvrl1,Fzd5,Ly6a,Notch2,Lipg,Slc9a1,Csf3r,Sell,Antxr1,Fcgr2b,Tnf,Il2rg,Cd200r4,Ccr1,Abcb1a,Pdgfb,Klrk1,Il13ra1,Ccrl2,Lpar1,Plaur,Cd80,H60b,Tnfsf4,Ly75,Cxcl9,Itgav,Axl,Lrp8,Il12b,Pdgfrb,Gpc1,Dcbld2,Cd55,A530064D06Rik,Rtp4,Lrp4,Cd40,Adgre4,Adgrg6,Itga4,Sdc4,Siglece,C3 |
| 6.668e-16 | -34.94 | GSE7460_TCONV_VS_TREG_THYMUS_DN | MSigDB lists | GSE7460_TCONV_VS_TREG_THYMUS_DN | 188 | 52 | 15632 | 1249 |
Ahr,Tmem176b,Prnp,Plagl1,Fcgr2b,Gadd45g,Dusp4,Phlpp1,Chst11,Bcl2a1b,Rgs1,Adam19,Sh3bgrl2,Notch2,Fam162a,Kif5c,Ebi3,Odc1,Plscr1,Oas1a,Tnfrsf1b,Casp4,Tnfsf14,Cd83,Mdfic,Cd38,Crim1,Prdm1,Mxd1,Rnf135,Gbp3,Itgb8,Cish,Tnfsf8,Pnp2,Bcl2a1d,Fgl2,Cd40,Osbpl3,Nfxl1,Bcl2a1a,Oas1g,Dusp5,Ptger4,Map3k8,Pim1,Nrp2,Stx11,Ccl5,Gch1,Myadm,Snx10 |
| 6.668e-16 | -34.94 | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP | 188 | 52 | 15632 | 1249 |
Xaf1,Mov10,Gbp7,Gem,Abtb2,Pmepa1,Wdr43,Cflar,Col27a1,Irf1,Asb13,Ifrd1,Tor1aip2,Myc,Ass1,Zc3hav1,Pfkfb3,Pnpt1,Adar,P2ry14,Il12rb1,Wars,Uba7,Slc7a5,Cd86,Nampt,Epsti1,Stip1,Trafd1,Dek,Inpp1,Lrp11,Tnfsf10,Tmem229b,Cxcl10,Naa25,Smox,Atp10a,Parp3,Treml2,Mlkl,Minpp1,Gbp4,Gbp9,Setdb2,Birc2,Axl,Hsph1,Ifit1,Gbp2,St3gal6,Trim12c |
| 6.845e-16 | -34.92 | WORSCHECH_TUMOR_REJECTION_UP | MSigDB lists | WORSCHECH_TUMOR_REJECTION_UP | 59 | 28 | 15632 | 1249 |
Ifi214,Stat2,Ccl22,Il1a,Tlr6,Nfkbiz,Ifi207,Ifi209,Ifi205,Msr1,Ifit1bl1,Ifi213,Il4i1,Irf4,Il2rg,Ifi204,Il1b,Tagap,Ccl4,Cxcl1,Mndal,Ccl5,Tnfrsf1b,Ifit1bl2,Ifi203,Ccrl2,Ifi208,Ifi211 |
| 7.357e-16 | -34.85 | regulation of cytokine-mediated signaling pathway | biological process | GO:0001959 | 105 | 35 | 20694 | 1406 |
Stap1,Sphk1,Zbp1,Vrk2,Rabgef1,Csf1,Adar,Ccl5,Cav1,Irf7,Ptpn2,Irak3,Irak2,Cd300lf,Il1rn,Gfi1,Cd74,Axl,Traf2,Syk,Nlrc5,Il6,Socs1,Ikbke,Irgm2,Ripk2,Parp9,Rffl,Mul1,Angpt1,Irgm1,Casp4,Samhd1,Parp14,Casp1 |
| 7.728e-16 | -34.80 | GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_UP | 158 | 47 | 15632 | 1249 |
Slc16a3,Slc2a1,P2ry13,Stat3,Gpr84,Ccnd1,Treml2,Rhoh,Ch25h,Sla,Myd88,Cd38,Etv5,Sesn3,Gja1,Ccr1,Klf2,Ddit4,Hk2,Hp,Mcm6,Grina,Thbs1,Htr2b,Pgk1,Spsb1,Cx3cr1,Pdpn,Ccr3,Fcgr2b,Nek6,Tpi1,Pgm1,Ccnd2,Cd34,Ahr,Klf7,P4ha1,C1rl,Nos2,Tnfsf14,Slc39a14,Socs3,Sema4c,Pmepa1,Nfil3,Pfkl |
| 8.027e-16 | -34.76 | LINDSTEDT_DENDRITIC_CELL_MATURATION_B | MSigDB lists | LINDSTEDT_DENDRITIC_CELL_MATURATION_B | 51 | 26 | 15632 | 1249 |
Maff,Adora2a,Usp12,Psme2,Rel,Nfkb1,Birc3,Il15ra,Tnip1,Nfkb2,Tnfaip2,Cflar,Lyn,Nr4a3,Casp7,Dusp4,Optn,Nfkbia,Relb,Tnfaip3,Tap1,Cd80,Sdc4,Cd83,Traf1,Marcksl1 |
| 8.142e-16 | -34.74 | MODULE_208 | MSigDB lists | MODULE_208 | 97 | 36 | 15632 | 1249 |
Isg15,Cd74,Pttg1,Gbp2,Hvcn1,Cd14,Il15,Oas3,Nlrc5,Ifit1bl1,Klf6,Cebpd,Sdc2,Ifi44,Peli1,Fpr1,Kcna3,Oas1g,Cd200,Ifi35,H2-Ab1,Trem1,Thbs1,Tnfsf10,Adam19,Cmklr1,Vcam1,Cd86,Samsn1,Rnf31,Ifit1bl2,Kctd12,Csf3,Oas1a,Plscr1,H2-Aa |
| 9.516e-16 | -34.59 | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN | 177 | 50 | 15632 | 1249 |
Gadd45b,Nfkbia,Bcl2a1b,Sod2,Ets2,Gclm,Parp14,Ncoa5,Scarf1,Ddx60,Fbxo4,Clec4e,Tap1,P4ha1,Ifit3,Mov10,Procr,Slpi,Stat4,Ebi3,C3,Irf1,Ifit3b,Ier3,Abcc1,Sp140,Txnrd1,Psmb9,Serp1,Mgat1,B3gnt5,Bcl2a1d,Ch25h,Il1a,Dtx3l,Sphk1,Txn1,Tap2,Map2k1,Atp6v1d,Parp12,Psmb6,Grina,Mob3b,Ak4,Nr4a3,Bcl2a1a,Il1rn,Prkx,Plaur |
| 9.623e-16 | -34.58 | MODULE_15 | MSigDB lists | MODULE_15 | 340 | 74 | 15632 | 1249 |
Ctsc,Myc,Fos,Tspan3,Jun,Ets2,Zyx,Slc7a11,Ifi207,Angpt1,Cd34,Pttg1,Ccnd2,Cdk5r1,Gbe1,Ifi214,Atf3,Ifi203,Cd69,Eef1e1,Ifi211,Fabp7,Gna15,Lmo4,Mndal,Psmb8,Nfil3,Adam19,Rgs1,Hcls1,Ifi204,Lyn,Rac3,Pim2,Pnp2,Traf2,Psmb9,Slc2a1,Ifi205,Csf3r,Birc2,Ifi209,Ifi213,Cst7,Sell,Plk3,Itga4,Hhex,Oas2,Hap1,Dgka,Maff,Ube2l6,Ddit4,Nmi,Ifi208,H2-Aa,Lcp2,Hopx,Ppp1r15a,Fosb,Serpine1,Junb,Plek,Jarid2,Psd4,Il1b,Glrx,Cxcl1,Pim1,Mcm6,Nsmaf,Il2rg,H2-Ab1 |
| 1.009e-15 | -34.53 | GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_DN | MSigDB lists | GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_DN | 165 | 48 | 15632 | 1249 |
Il12rb1,Inhba,Wars,Ube2l6,H2-Aa,Irf7,Sipa1l1,Card6,Plaur,Epsti1,Ppp2r2a,Il1b,Bcl2a1a,Cxcl1,Serpinb2,Ptgs2,H2-Ab1,Dusp5,Bcl2a1d,Rsad2,Pnp2,Psmb9,H2-Q6,Dync1h1,Tnf,Casp1,Stat2,Cd74,Gbp3,H2-Q7,Trim21,Psme2,Cenpj,Psmb8,Plekhn1,Irf1,Stat1,Ifrd1,Scarf1,Samd9l,Parp14,Dnaja1,D16Ertd472e,Nlrc5,H2-Q4,Bcl2a1b,Tap1,Rtp4 |
| 1.102e-15 | -34.44 | GO_CELL_ACTIVATION | MSigDB lists | GO_CELL_ACTIVATION | 534 | 99 | 15632 | 1249 |
Bcl6,Klf6,Treml2,Rsad2,Batf2,Tnfsf8,Cd74,Psmb10,Ifna2,Batf,Lcp2,Fzd5,Plek,Ccl5,Csrp1,Icosl,Stxbp3,Nr4a3,Il18,Tlr3,Ripk2,Htr2b,Vcam1,Nfkb2,Ptpn2,Spn,Syk,Ifnb1,Ifna5,Cx3cl1,Fas,Nck1,Stxbp1,Il15,Slamf7,Cd80,Clec4e,Casp8,Atm,Pou2f2,Csf1,Lyn,Dgkh,Notch2,Swap70,P2ry12,Itpr1,Timp1,Cd40,Axl,Src,Ifnar1,Icam1,Cd180,Jmjd6,Malt1,Hhex,Itga4,Rhoh,Ripk3,Relb,Cd86,Slc7a2,Pik3r6,Dgka,Tlr1,Ifna6,Cxcl10,Il12b,Clec4d,Ptger4,Pf4,Plcl2,Jun,Cx3cr1,Slc7a11,Pik3r5,Irf4,Edn1,Ikzf1,Prkce,Il6,Pdpn,Egr1,Ifna1,Itgal,Il10,Tnfsf14,Gna15,Rasgrp1,Plscr1,Irf1,Sema4a,Pik3cd,Azi2,Tnfsf4,Ebi3,Clcf1,Actb |
| 1.116e-15 | -34.43 | developmental process | biological process | GO:0032502 | 5572 | 510 | 20694 | 1406 |
Ifna6,Nck1,Acvrl1,Slfn5,Phf6,Cdkn1a,Rbbp8,Casp8,Pikfyve,Zfp513,Katna1,Gys1,Pla2g4a,Etv5,Vezt,Sdc4,Cacybp,Sik3,Inpp5b,P2ry12,P2ry2,Ifitm1,Bnip3,Ednrb,Psmb10,Agrn,Il12b,Mosmo,Clic4,Stxbp3,Tmem67,Slc7a5,Srgn,Nrp2,Lhx2,Tnfsf9,Casp2,Bmp2,Nfkb2,Acvr1b,Ttc39c,Cnn2,Phgdh,Lox,Btg2,Lrrc8c,Ifna1,Acp5,Tet2,Diaph2,Il1b,Acp2,Sla,Nfkb1,Rcn1,Keap1,Cdk5r1,Slamf8,Med21,Slc30a1,Adrb2,Evl,Batf,Ccl2,Psmb8,Azi2,Herc6,Golga3,Apobec3,Kif5c,Tnc,Ifna2,Arid4a,Socs3,Stat5a,Pdpn,Socs1,Pnpt1,Plagl1,Pdgfrb,Cebpd,Ptpn2,Fzd5,Ptk2,Prag1,Rac3,Kdm5b,Prkx,Etv6,Nr1h3,Tle3,Spen,Antxr1,Hspa2,Ifrd1,Sipa1l1,Igsf9,Col18a1,Csf1,Nupr1,Il15,Nr3c1,Bcl2l11,Odc1,Fpr2,Snx10,Eif4g2,Map2k1,Dock10,Slc25a25,Lif,Flt1,Arg2,Vcan,Heatr9,Psma6,Gpc1,Plac8,Tnfrsf1b,Rgs14,Akt3,Rap1gap2,Sphk1,Tcea1,Jak2,Errfi1,Inhba,Tnfaip3,Rictor,Angpt1,Ikzf1,Atf3,Rasgrp1,Ccl12,Taf4b,Cited2,Stxbp1,Tcf4,Jun,Rsad2,Tnf,Il1a,Rpgrip1l,Col27a1,Aida,Arid5b,Insl6,Pou3f1,Tnfaip2,Nlgn2,Mycl,Rbl1,Psd,Uchl1,Irs2,Kat2b,Jmjd6,Icam1,Pik3cd,Rapgef2,Spn,Plscr1,Tpi1,Rap2c,Marf1,Ddx4,Cyfip1,Casz1,Bcl9,Syne2,Mmd,Ier2,Ptgs2,Mgat1,Plcl2,Etv3,Mmp9,Sirt1,Il15ra,Cd164,Dbnl,Sqstm1,Tagln,Samd9l,Itpr1,Tmeff1,Acod1,F11r,Klf7,Cav1,Osm,Pbx1,Myadm,Spire1,Irf1,Cx3cr1,Dach1,Il10,Rab21,Asf1a,Cnp,Intu,Map2k4,Plpp3,Cenpe,Lnpk,Usp42,Kif3c,Tspo,Itga4,Irf4,Mmp14,Sav1,Ccr3,Casp7,Socs7,Rai14,Trip13,Edn1,Sema4c,Frmd6,Papss2,Fas,B3gnt5,Casp4,Tut7,Clec5a,Hsd17b7,Micall2,Hap1,Casp1,Jarid2,Ldlr,Rrs1,Rilpl1,Mthfr,Ifna5,Lrp4,Hlx,Mul1,Stk40,Gpd2,Serpinb6b,Tmod3,Sgcb,Zc3h12a,Il18,Prokr1,Trip10,Gfi1,Scarf1,Foxp4,Sbds,Gpr18,H3f3b,Zfp281,Ift57,Mafk,Serp1,Myd88,Met,Arid5a,Shisa3,Fcgr2b,Col11a2,Kdr,Egr2,Setdb2,Kitl,Cx3cl1,Bcl6,Plod3,Fabp7,Gdf15,Mmp25,Slc4a7,Pdlim7,Rcan1,Mark2,Rnd1,Cgas,Kdm6b,Gadd45b,Spred3,Ext1,Cxcl14,Eno1,Vcam1,Calcrl,Zhx2,Notch2,Rab10,Egr1,Thbs1,Plk2,Cd34,Prnp,Fbxo4,Sema4a,Samhd1,Il6,Kdm4a,Hif1a,Itga5,Vasp,Cflar,Sap30,Jag1,Mdm2,Clmp,Pdgfc,Palld,Fubp1,Mapkapk2,Tal2,Ppp2r3a,Hmga2,Itgav,Cemip2,Gja1,Dnaaf3,Casp3,Zmynd15,Relb,Ccnd1,Nr4a3,Slc9a1,Apaf1,Spic,Bbx,Ezr,Ddit4,Sdc2,Mecp2,Ppp2r1b,Phactr4,Tulp3,Vegfc,Znrf3,Hopx,Myc,Plagl2,Ppp4r2,Dync1i2,Zeb1,Klf2,Ntng2,Triobp,Csrnp1,Birc2,Spry2,Sema3c,Egr3,H2-Ab1,Plekha5,Hck,Stat3,Src,Lst1,Hcls1,4932438A13Rik,Dst,Ero1l,Pdgfb,Klrk1,Mafg,Lpar1,Arl4a,Batf2,Dnase1l3,Pou2f2,Swap70,Mthfd1l,Apba1,Crkl,Bcor,Stat1,Flrt3,Spint2,Adar,Maff,Ripk3,Prdm1,Col4a2,Pml,Ccr1,Ciapin1,Eya4,Syk,Pde3b,Sod2,Fzd1,Zswim4,Snx2,Ifi204,Ccl3,Sec24b,Actb,Malt1,Junb,C3,Cd74,Fgr,Ankrd17,Fndc3a,Igf1r,Nox1,Wars,Tshz1,Ifnb1,Ccl5,Timeless,Cd38,Slc39a13,Cdyl,Adgrl2,Atm,Nes,Mturn,Rmdn3,Abr,Fos,Bcl2a1d,Arf4,Csrp1,Fam20c,Txnrd1,Hp,Irf8,Axl,Gpsm2,Pik3r6,Hhex,Rab32,Ptch1,Htr2b,Lmo4,Atp11a,Chst11,Lyn,Slc7a11,Kremen1,Parp11,Sdc1,Ahr,Clcf1,Hdac1,Ust,Adgrg6,Adam19,Plau,S100a8,Nr4a1,Hinfp,Plaur,Acvr1,Tnfsf4,Xkr8,Abcb1a,Ptger4,Mov10,Mmp13,Ets2,Ehd1,Adora2a,Rnf114,Gadd45g,Zfp36,Morc3,Itgb8,Clic5,Nectin2,Hivep3,Tent2,D16Ertd472e,Tsku,Stap1,Xrn1,Homer1,Serpine1,Tmem176b,Adap2,Flrt2,Lrp8,H2-Q7,Map4k4,Csf3,Icosl,Ptprj,Tlk2,Tnfsf8,Scn1b,Spred1,Htra1,Ifna4,Smc5,Tab2,Nos2,Cd300lf,Tiparp,Pid1,Rhoh,Notch1,Flnb,Tdrd7,Gsta3,Clec4e,Hmox1,Tlr2,Clec4d |
| 1.123e-15 | -34.42 | regulation of reactive oxygen species metabolic process | biological process | GO:2000377 | 198 | 49 | 20694 | 1406 |
Klrk1,Pdgfb,Il6,Hif1a,Arg2,Cflar,Ptgs2,Cd34,Thbs1,Stat3,Fpr2,Ass1,Pdk3,Hk2,Acod1,Tlr6,Jak2,Cav1,Ripk3,Tlr2,Trim30a,Arf4,Il18,Acp5,Sirt1,Ier3,Zc3h12a,Hp,Pid1,Il1b,Atp2b4,Syk,Ptger4,Cxcl1,Sod2,Tspo,Tnf,Plau,Il10,Cx3cr1,Birc3,Cdkn1a,Gch1,Klf2,Birc2,Nox1,Icam1,Bnip3,Pdgfrb |
| 1.157e-15 | -34.39 | GSE360_DC_VS_MAC_M_TUBERCULOSIS_UP | MSigDB lists | GSE360_DC_VS_MAC_M_TUBERCULOSIS_UP | 184 | 51 | 15632 | 1249 |
Psme2,Isg20,Trim14,Etv6,Nfkb1,Ifit3,Ccl4,Oasl1,Pim2,Ifi35,Ifit3b,Irf1,Trib1,Il6,Gpr35,Ctsc,Agrn,Ccl12,Ifit1bl1,Gadd45b,Dnase1l3,Palld,Ccl22,Nrp2,Uba7,Oas2,Ccl5,Brd2,Ifit1bl2,Slc7a8,Txn1,Il1rn,Trafd1,Sp110,Dusp5,H2-Ab1,Ptger4,Smox,Cxcl10,Kif3c,Cers6,Rbpms,Txnrd1,Cst7,Dync1h1,Rbbp8,Traf5,Cd83,Ch25h,Traf1,Stat2 |
| 1.162e-15 | -34.39 | response to protozoan | biological process | GO:0001562 | 37 | 21 | 20694 | 1406 |
Batf2,Il4ra,Irgm2,Gbp7,Gbp9,Iigp1,Gbp2b,Il6,Gbp8,Cd40,Il12b,Gbp3,Ccdc88b,Il10,Irf8,Ier3,Irf4,Batf,Gbp2,Pf4,Spn |
| 1.218e-15 | -34.34 | Immunity-related_GTPase-like | interpro domains | IPR007743 | 15 | 14 | 19984 | 1430 |
Irgm1,Gm4841,Gm12185,F830016B08Rik,Ifi47,Tgtp1,9930111J21Rik2,Gm5431,Iigp1,9930111J21Rik1,Gm12250,Gm4951,Igtp,Irgm2 |
| 1.255e-15 | -34.31 | GO_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE | 125 | 41 | 15632 | 1249 |
Lyn,Serpinb9,Il12b,Ifi204,Hmox1,Cd55,Tnfsf4,Trafd1,Mndal,Samsn1,Il10,Rabgef1,Ifi203,Ifi208,Nmi,Ifi211,Nr1h3,Il4ra,Ifi214,Mul1,Hlx,H2-Q7,Abr,Angpt1,Irak3,Tnfaip3,Tap1,Ifi207,Adar,Ifi209,Bcl6,Ptpn2,Ifi205,H2-Q6,Tnf,H2-Q4,Spn,Nlrc5,Ifi213,Dhx58,Ifnb1 |
| 1.267e-15 | -34.30 | negative regulation of cytokine production | biological process | GO:0001818 | 258 | 57 | 20694 | 1406 |
Relb,Nfkb1,Tnfaip3,Hmox1,Tlr2,Trim30a,Cd200,Gpr18,Errfi1,Acod1,Tlr6,Axl,Lgals9,Cd274,Cd83,Nlrp3,Dhx58,Acp5,Sirt1,Zc3h12a,Mul1,Gbp4,Il6,Arg2,Rel,Nmi,Nfkbil1,Cd34,Thbs1,Prnp,Nod2,Ifnb1,Rgcc,Srgn,Rabgef1,Klf2,Mefv,Il12b,Bcl6,Irak3,Zfp36,Tspo,Cx3cl1,Mapkbp1,Tnf,Ptger4,Cmklr1,D1Ertd622e,Il10,Pml,Ezr,Cx3cr1,Tnfsf4,Fcgr2b,Tlr9,Angpt1,Met |
| 1.274e-15 | -34.30 | CASTELLANO_NRAS_TARGETS_UP | MSigDB lists | CASTELLANO_NRAS_TARGETS_UP | 69 | 30 | 15632 | 1249 |
Il1rn,Fndc3a,Stat1,Il13ra1,Ifi35,Ifi204,Ifi208,Ifi211,Kctd12,Ifi203,Mmp13,Gja1,Ifit1bl2,Psmb8,Mndal,Lcn2,Tap1,Ifi207,Cx3cl1,Ifih1,Ifi214,Isg15,Usp18,Sdc1,Irgm2,Nqo1,Ifit1bl1,Ifi213,Ifi209,Ifi205 |
| 1.276e-15 | -34.30 | GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_UP | MSigDB lists | GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_UP | 172 | 49 | 15632 | 1249 |
Slc31a2,Arl5b,Pdgfb,Maff,Dusp5,Zc3h12a,Ptger4,Kdm6b,Spata5l1,Osgin2,Cldnd1,Sec24b,Plaur,Slc16a3,Ehd1,Eno1,Tank,Fchsd2,Ccng2,Mafk,Ch25h,Sertad3,Sav1,Bfar,Mcmbp,Ahrr,Birc3,Zc3h12c,Rel,Ppp4r2,Usp12,Ell2,Tmod3,Sema4c,Ccl4,Rgs1,Gfpt1,Cflar,Fam162a,Trim36,Jun,Dusp2,Gpr35,Chst11,Nck1,Atf3,Etv3,Pim3,Sdc4 |
| 1.282e-15 | -34.29 | positive regulation of cell population proliferation | biological process | GO:0008284 | 969 | 134 | 20694 | 1406 |
Itga4,Myc,Htr2a,Pdgfrb,Ptk2,Kdm5b,Ccr3,Edn1,Serpine1,Col18a1,Nod2,Csf1,Il15,Hdac1,Adrb2,Tlr9,Plau,Ccl2,Cx3cr1,Il10,Nr4a1,Tnfsf4,Mecp2,Vegfc,Ptger4,Bst1,Tnc,Tspo,Stat5a,Cxcl1,Plac8,Optn,Abcc4,Itgal,Il18,Pid1,Akt3,Notch1,Marcksl1,Sphk1,Crkl,Timp1,Stat1,Jak2,Tnfaip3,Il12rb1,Rictor,Pim1,Traf5,Hmox1,Cox17,Peli1,Egr3,Stat3,Csf3,Hck,Gcnt2,Icosl,Odc1,Hcls1,Lif,Pdgfb,Cxcl10,Flt1,Htra1,Ptafr,Hlx,Ripk2,Bcl6,Ednrb,Ccdc88b,Cd74,Il12b,Nlgn2,Igf1r,Cd40,Nox1,Phip,Vcam1,Notch2,Calcrl,Irs2,Ccl5,Egr1,Sinhcaf,Nck1,Acvrl1,Myd88,Atf3,Cdkn1a,Pml,Nampt,Pla2g4a,Etv5,Taf4b,Syk,Kdr,Bambi,Kitl,Jun,Cx3cl1,Tnf,Mdm2,Pdgfc,Sirt1,Mmp9,Il1b,Cd274,Hmga2,Itpr1,Itgav,Htr2b,Lyn,Cav1,Osm,Ccnd1,Pbx1,Nr4a3,Clcf1,Thbs1,Cd38,Lhx2,Spn,Tnfsf9,Adora2b,Bmp2,Cd86,Il6,Cd80,Ccnd2,Hilpda,Hif1a,Cflar,Ptgs2 |
| 1.287e-15 | -34.29 | GSE14386_UNTREATED_VS_IFNA_TREATED_ACT_PBMC_MS_PATIENT_DN | MSigDB lists | GSE14386_UNTREATED_VS_IFNA_TREATED_ACT_PBMC_MS_PATIENT_DN | 148 | 45 | 15632 | 1249 |
Zc3h12c,Ifit3,Ptch1,Birc3,Ccrl2,Fabp7,Isg20,Ifit3b,Dusp16,Nfil3,Ets2,Eif2ak2,Nr4a1,Ccl12,Bcl2l11,Vcan,Taf4b,Irf4,Ubash3b,Rtp4,Arrdc4,Irf7,Nampt,Bst1,Maff,Pde7b,Parp12,Stx11,Phlda1,Cxcl10,Serpinb9,Fpr1,P2ry13,Fgl2,Rsad2,Stat3,Ifi44,Cd180,Ddx58,Hif1a,Mxd1,Ier2,Cd38,Mdfic,Batf |
| 1.287e-15 | -34.29 | GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE | 148 | 45 | 15632 | 1249 |
Dhx58,H2-Q6,Ifi205,Ifi209,Ifi213,Tnfaip3,Irak3,Calcrl,H2-Q7,Nmi,Ifi208,Ifit1bl2,Trafd1,Il12b,Serpinb9,Ptger4,Zc3h12a,Ptpn2,Eif2ak2,Spn,Nlrc5,Cx3cr1,Ifit1bl1,H2-Q4,Ifi207,Tap1,Adar,Ifi214,Mul1,Nr1h3,Nlrp3,Abr,Smpdl3b,Ifi203,Ifi211,Htra1,Il10,Mndal,Rabgef1,Tnfrsf1b,Nfkb1,Ifi204,Adrb2,Mefv,Socs3 |
| 1.334e-15 | -34.25 | IIGP | pfam domains | PF05049 | 15 | 14 | 18711 | 1348 |
Gm12185,Iigp1,9930111J21Rik2,Irgm1,Gm5431,Gm4841,Gm4951,Igtp,Gm12250,Irgm2,Tgtp1,9930111J21Rik1,Ifi47,F830016B08Rik |
| 1.374e-15 | -34.22 | KRASNOSELSKAYA_ILF3_TARGETS_UP | MSigDB lists | KRASNOSELSKAYA_ILF3_TARGETS_UP | 44 | 24 | 15632 | 1249 |
Ifi205,Ifi209,Psmb9,Ifi213,Ifit1bl1,Ifi214,Isg15,Tap1,Ifi207,Plau,Mndal,Ifit3,Ifit1bl2,Ifi203,Xaf1,Oas1a,Plscr1,Ifi208,Ifi211,Ifit3b,Ifi204,Oas1g,Stat1,Ifi35 |
| 1.392e-15 | -34.21 | GO_REGULATION_OF_MAP_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_MAP_KINASE_ACTIVITY | 306 | 69 | 15632 | 1249 |
Cd40,Rgs14,Traf2,Dusp1,Tnf,Src,Dbnl,Dusp8,Cd74,Tab2,Mdfic,Irak3,Daxx,Pdgfc,Rgs3,Bmp2,Nod1,Map2k1,Pdgfrb,Pik3r6,Fzd5,Dusp6,Pdgfb,Map3k8,Fpr1,Trib3,Adora2b,Ripk2,Dusp5,Uchl1,Ptprj,Crkl,Htr2b,Il1b,Thbs1,Irak2,Kitl,Dnaja1,Syk,Pik3r5,Flt1,Gadd45b,Eif2ak2,Map3k6,Pde5a,Dusp4,Gadd45g,Nod2,S1pr2,Dusp2,Spry2,Edn1,Mul1,Tlr6,Mapkapk2,Dusp14,Spred1,Htr2a,Cav1,Ikbkg,Rasgrp1,Lyn,Trib1,Lpar1,Aida,Tlr9,Dusp16,Igf1r,Jak2 |
| 1.414e-15 | -34.19 | GO_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | GO_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 335 | 73 | 15632 | 1249 |
Tlr2,Trib1,Mtdh,Tlr9,Tnfsf4,Gfi1,Tax1bp1,Jak2,Cflar,Ptch1,Il10,Ikbkg,Nfkb1,Rnf31,S100a8,Sirt1,Med13,Nfkbib,Trim21,Trim14,Nlrp3,Trim13,Prnp,Lrp8,Jun,Nlrc4,Fos,Psmd10,Syk,Nlrc5,Nfkbia,Eif2ak2,Nod2,Peli1,Il6,Arid5b,Pim1,Hmox1,Zc3h12a,Ripk2,Tlr3,Il1b,Keap1,Nfkb2,Irak2,Cmklr1,Fzd1,Nfkbid,Trim26,Sphk1,Traf1,Trim12c,Tab2,Ddx58,Icam1,Parp10,Aim2,Nfkbil1,Malt1,Irak3,Tnfaip3,Hck,Ripk3,Pbx1,Nod1,Sgk3,Traf5,Sav1,Cd40,Hspa1a,Traf2,Tnf,Psma6 |
| 1.427e-15 | -34.18 | HORIUCHI_WTAP_TARGETS_UP | MSigDB lists | HORIUCHI_WTAP_TARGETS_UP | 264 | 63 | 15632 | 1249 |
Ifit3b,Cd200,Casp7,Endod1,Nfil3,Dnajb2,Col27a1,Gfpt1,Ifit3,Ednrb,Birc3,Jag1,Zscan29,St3gal5,Csf1,Prnp,Atf3,Sdc4,Il15,Rapgef5,Sod2,Ccl12,Tagln,Hivep2,Flt1,Dusp4,Ifrd1,Peli1,Kcnj2,Arid5b,Hmox1,Pcgf5,Dusp5,Tlr3,Smox,Htr2b,Tfec,Lacc1,Epsti1,Inpp1,Gcnt2,Bambi,Vcam1,Acsl5,Cxcl1,Cxcl2,Bst1,Ifih1,Icam1,Itga4,Tnfaip3,Olfml3,Itpr1,Casp1,Ifit2,Tapbp,Rsad2,Cebpd,Sele,Arhgap26,Ly75,Ifi44,Nr3c1 |
| 1.477e-15 | -34.15 | GSE17721_LPS_VS_POLYIC_1H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_1H_BMDC_UP | 185 | 51 | 15632 | 1249 |
Tnfaip2,Frmd6,Cdkn1a,Azi2,Tlr2,Csf1,Plscr1,Flnb,Zfp36,Sirt1,Zc3h12c,Lap3,Hdc,Pim3,Rnd3,Dusp14,Nlrp3,Cdk5r1,Irf4,Il18bp,Ifnb1,Gadd45b,Bcl2l11,Fos,Msr1,Tiparp,Ets2,Slfn3,Tnfsf10,Tfec,Ptger4,Chic2,Cdc42ep4,St7,Maff,Slc4a7,Junb,Lcp2,Slfn4,Klf2,Med21,Il1a,Spata13,Icam1,Dusp8,Errfi1,Cebpd,Klf6,Timp1,Arhgef3,Serp1 |
| 1.484e-15 | -34.14 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP | 52 | 26 | 15632 | 1249 |
Slc7a11,Ifi213,Klf6,Ifi205,Ifi209,Nqo1,Vcan,Rbpms,Tmem176b,Ch25h,Ifi214,Gbp2,Ifi207,Dusp6,Gdf15,Mndal,Phlda1,Ifi208,Ifi211,Ifi203,Cd200,Uchl1,Acsl1,Ifi204,Plat,Il1rn |
| 1.569e-15 | -34.09 | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_24H_INCUBATION_DN | MSigDB lists | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_24H_INCUBATION_DN | 179 | 50 | 15632 | 1249 |
Casp1,Axl,Carhsp1,Arhgap26,Nupr1,Rab19,Sla,Cd83,Batf,Ripk3,Jarid2,Rgl1,Samsn1,Hap1,Stx11,Il12rb1,Zc3h12a,Oas1g,Rnf19b,St3gal1,Ttc39b,Il18,Map3k8,Arid5b,Kcna3,Glrx,Pkp4,Gadd45b,Plac8,Cyfip1,Abcb1a,Dusp4,Chst11,Mapkapk2,Fas,Fbxo4,Cd80,Casp4,Mcm9,Plscr1,Ksr1,Oas1a,Rnf19a,Cd200,Ell2,Endod1,Fam111a,Adam19,Znrf1,Cacna1d |
| 1.754e-15 | -33.98 | negative regulation of phosphorylation | biological process | GO:0042326 | 460 | 81 | 20694 | 1406 |
Crkl,Casp3,Errfi1,Ppp2r5a,Tnfaip3,Cav1,Lyn,Trib1,Tnip1,Adar,Myadm,Psmd10,Zc3h12a,Ier3,Il18,Sirt1,Trib3,Rgs14,Pid1,Il1b,Rhoh,Hhex,Il6,Spred1,Lif,Dusp1,Gbp4,Dusp8,Mvp,Fam72a,Hsph1,Prnp,Dusp5,Stat3,Fam129a,Ptprj,Dusp2,Igf1r,Prkar2b,Dnaja1,Wars,Stap1,Dusp16,Uchl1,Spry2,Kat2b,Irs2,Cdkn2d,Nupr1,Pmepa1,Rabgef1,Irak3,Gadd45g,Aida,Dusp4,Actb,Ppp1r15a,Ptpn2,Samsn1,Spred3,Gadd45b,Plpp3,Ubash3b,Dusp6,Socs3,Jun,Socs1,Adora2a,Slfn1,Phlpp1,Nck1,Irf1,Angpt1,Met,Birc3,Cdkn1a,Atf3,Parp14,Ezr,Ddit4,Ppp1r15b |
| 1.806e-15 | -33.95 | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | 218 | 56 | 15632 | 1249 |
Zhx2,Dusp5,Nr4a3,Phyh,Tbc1d13,Spint2,Inhba,Csrp1,Map4k4,Txn1,Fzd5,Cd86,Traf5,Cd83,Itga4,Marcksl1,St3gal6,Traf1,Fchsd2,Ly75,Rab9,Rab11fip1,Casp3,Ccng2,Cers6,Cebpd,Plekha5,N4bp1,Ldlr,Adam19,Fscn1,Gfpt1,Cflar,Cdkn1a,Filip1l,Il13ra1,Ebi3,Ms4a6d,Zfp36,Egln3,Jag1,Birc3,Cep350,Cd80,Sdc4,Bcor,Ccl22,Ccl2,Peli1,Irf4,Optn,Vcan,Plac8,Gadd45b,Map3k6,Trip10 |
| 1.858e-15 | -33.92 | regulation of secretion by cell | biological process | GO:1903530 | 831 | 120 | 20694 | 1406 |
Rhbdf2,Nos2,Ripk2,Tnfsf15,Traf2,Arg2,Ptafr,Lif,Sec24a,Hap1,Casp1,Clec5a,Src,Gpr68,Map4k4,Casp4,Nr3c1,Ddx58,Cd200,Clec4e,Frmd4a,Hmgn3,Hmox1,Tlr2,Inhba,Tnfaip3,Jak2,Tlr6,Sphk1,Nlrp3,Notch1,Zc3h12a,Tnfrsf1b,Apba1,Clec4n,Aim2,Socs1,Adora2a,Rab11fip1,Mmp13,Vegfc,Ptger4,Tnfsf4,Glrx,Rab21,Il10,Ezr,Hdac1,Tlr9,Adrb2,Slc30a1,Hcar2,Nod2,Edn1,Ifih1,Kmo,Kdm5b,Nr1h3,Fzd5,Htr2a,Abr,Hif1a,Il6,Adora2b,Rab9,Cd38,Cd34,Sdc1,Clcf1,Prkce,Klf7,Tnfrsf14,Lyn,Il4ra,Osm,Gja1,Htr2b,Rims3,Ifnar1,Il1b,Hmga2,Pim3,Cd274,Lgals9,Sirt1,Cx3cl1,Tnf,Mapkbp1,P2ry2,Ccl3,Il1a,P2ry12,Cacna1d,Rsad2,Stxbp1,Syk,Pde3b,Rasgrp1,Arid5a,Sdc4,Pml,Serp1,Angpt1,Rab10,Ccl5,Srgn,Rabgef1,Rgcc,Hk1,Slc16a1,Irs2,Stxbp3,Fgr,Nlgn2,Pfkl,Cd40,Il1rn,Tlr1,Gsdmd,Cd14 |
| 1.881e-15 | -33.91 | GSE17721_LPS_VS_CPG_16H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_16H_BMDC_UP | 186 | 51 | 15632 | 1249 |
Asb13,Pmepa1,Wdr43,Gfi1,Cdkn1a,Cflar,Gbp7,Nos2,Lap3,P4ha1,Rabgef1,Psmb8,Tdrd7,Psme2,Ppp4r2,Atxn7l1,Trim21,Sass6,P2ry14,Slc30a1,Samhd1,Col4a2,Il15,F10,Ptpn2,Msr1,Plac8,Hivep2,Crbn,Klf3,Ccl2,Atp10a,Slc29a3,Slfn3,Irf7,Slfn4,Eya4,Ifih1,Pml,Itga4,Mapkbp1,Csf3r,Cd40,Tpst1,Psmb9,Slc25a37,Rsad2,Aebp2,Top3a,Carhsp1,Batf2 |
| 2.008e-15 | -33.84 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_DN | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_DN | 180 | 50 | 15632 | 1249 |
Wdr43,Fam102b,Znrf1,Adam19,Pik3cd,Etnk1,Pim2,C3,Socs3,Mmd,Syne2,Csf1,Cysltr2,Atp2b4,Il4ra,Nfkbiz,Lrp8,Taf4b,Irf4,Ikzf1,Il6,Myc,Ccl12,Srm,Slc37a3,Il1b,Pim1,Arid5b,Pcgf5,Ldha,Slc25a12,Cxcl2,Slc7a5,Lcp2,Rrs1,4930523C07Rik,Junb,Mthfd1l,Batf,Rab19,Il1a,Hif1a,Upp1,Tab2,Socs1,Cish,Itgb8,Arid5a,Bcl6,Eno1 |
| 2.008e-15 | -33.84 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN | 180 | 50 | 15632 | 1249 |
Cd86,Asns,4930523C07Rik,Dusp6,Wars,Fzd1,Tlr1,Slc43a3,Ptafr,Bcl2a1a,Il1rn,Tnfsf10,Clic4,Homer1,Psmb9,Txnrd1,Mecp2,Psma6,Bcl2a1d,Phgdh,Sat1,Rnf24,Egr2,Psmb10,Rgs3,Gbp2,Sav1,Cd14,Ifit3,Tnfsf14,Lap3,Lmo4,Pstpip2,St3gal5,Rcn1,Acvr1b,Ifit3b,Mthfd2,Lyn,C3,Jak2,Tspan3,Dock4,Sqstm1,Dhrs9,Bcl2a1b,Cpd,Etv3,Slc30a1,Atf3 |
| 2.008e-15 | -33.84 | GSE30083_SP2_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP2_VS_SP4_THYMOCYTE_DN | 180 | 50 | 15632 | 1249 |
Ms4a6d,Ifit3b,Endod1,Socs3,Clcf1,Gna15,Ifit3,Irf8,Gem,Stat4,Oas1a,Syne2,Tap1,Sdc4,Pde3b,Spn,Ifit1bl1,Klf3,Fam43a,Rin2,Ttc39b,Oas1g,5430427O19Rik,Daam1,Hopx,Ifit1bl2,Snx10,Plek,Tlr1,Aim2,Itga4,Hhex,Lif,Hvcn1,Daxx,Cd38,Traf5,Nod1,Crlf3,1600014C10Rik,Dse,Ttc39c,Casp1,Fgl2,Ccnd1,Gpr68,Rab21,Rhoq,Ly75,Ifi44 |
| 2.034e-15 | -33.83 | BAELDE_DIABETIC_NEPHROPATHY_DN | MSigDB lists | BAELDE_DIABETIC_NEPHROPATHY_DN | 397 | 81 | 15632 | 1249 |
Prkar2b,Rbms1,Cflar,Tmem123,Tax1bp1,Odc1,Mthfd2,Ifi35,Mtdh,Cd200,Stat1,Oas1a,Htra1,Plscr1,Sema3c,Plod2,Clic5,Birc3,Dusp14,Tap1,Zc3hav1,Sdc4,Palld,Vcan,Ap3b1,Sdc2,Optn,Rai14,Tspan3,Cited2,Dnaja1,Morc3,Ifit1bl1,Agrn,Itgav,Cxcl1,Rsbn1,Rcan1,Mcm6,Lox,Arid5b,Ptger4,Cd55,Oas1g,Wars,Oas2,Maff,Ube2l6,Nmi,Phlpp2,Myo1b,Flrt2,Med21,Serpine1,Nampt,Ifit1bl2,Pde4b,Gja1,Crim1,Cd164,Bmp2,St3gal6,Isg15,Nupr1,Mecp2,Cers6,Cebpd,Hspa2,C1ra,Tapbp,Psma6,Rab21,Nr3c1,Ifi44,Psmb9,Timp1,Birc2,Dusp1,Axl,Casp1,N4bp1 |
| 2.039e-15 | -33.83 | RODWELL_AGING_KIDNEY_UP | MSigDB lists | RODWELL_AGING_KIDNEY_UP | 420 | 84 | 15632 | 1249 |
H2-Ab1,Usp31,Rtn1,Tgfbi,Slamf8,Map3k8,Vcam1,Bcl2a1a,Irak2,Lacc1,Vegfc,Trafd1,Slc12a9,Ccr1,Mthfd1l,Ccl5,Lcp2,Asns,Antxr1,Stoml1,Inhba,AA467197,Parp12,H2-Q7,Ddx58,Klf8,Dtx3l,Psmb10,Gnb4,Cd14,Cd38,Mvp,Axl,Plod3,Casp1,Ifnar1,H2-Q6,Psmb9,Timp1,Mgat1,Micall2,Tnc,Carhsp1,Ly75,Slc15a3,Glipr2,Tapbp,C1ra,Bcl2a1d,Dram1,Socs3,Ms4a6d,Pik3cd,Lyn,Fscn1,Tnfaip2,Rgs1,Col27a1,Hcls1,Abcc1,Psmb8,Birc3,Irf8,Psme2,Cd69,Nfkbiz,Fas,Ccnd2,Tap1,Samhd1,Nlrc5,Cx3cr1,H2-Q4,Ccl12,Tagln,Ppp1r14b,Bcl2a1b,Msr1,Ikzf1,Parp14,Il4i1,Vcan,Samd9l,Cxcl14 |
| 2.183e-15 | -33.76 | TSAI_RESPONSE_TO_IONIZING_RADIATION | MSigDB lists | TSAI_RESPONSE_TO_IONIZING_RADIATION | 144 | 44 | 15632 | 1249 |
Tnfrsf8,Cd80,Cd83,Batf,Plau,Col4a2,Plagl2,Tnfaip3,Tle3,Ahr,Cd164,Fas,Traf1,Pttg1,Myc,Irf4,Ccng2,Nfkbie,Casp1,Plod3,Nfkbia,Stat5a,Axl,Tank,Eno1,Tnfsf10,Ccl4,Nfkb2,Cflar,Jak2,Cdkn1a,Vegfc,Stat1,Max,Cxcl10,Nr4a3,Btg2,Dusp6,Gdf15,Nfkb1,Junb,Ccr1,Birc3,Med21 |
| 2.251e-15 | -33.73 | GSE9509_10MIN_VS_30MIN_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN | MSigDB lists | GSE9509_10MIN_VS_30MIN_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN | 150 | 45 | 15632 | 1249 |
Itgav,Flrt3,Tle3,Rbl1,Foxp4,Rnd3,Slc25a25,Cd34,Gmppb,Dtwd1,Sgms2,Pttg1,St3gal3,Abr,Pou2f2,Trip13,Timeless,Gem,Gfi1,Cd82,Arf4,Fam102b,Mthfd2,Acvr1b,Tmod3,Mecp2,Glipr2,N4bp1,Klf6,Sphk1,Icam1,Itga4,Hk2,Vasp,Cxcl2,Csf3,Tmeff1,Pdgfrb,Gja1,Bambi,Gtpbp2,Fpr1,Cox18,Grina,Fam53c |
| 2.256e-15 | -33.73 | GO_LOCOMOTION | MSigDB lists | GO_LOCOMOTION | 1009 | 153 | 15632 | 1249 |
Csf3r,Tnf,Slc16a3,Sele,F11r,Cd74,Asap3,Ccl3,Flrt2,Map2k1,Pdgfrb,Pde4b,Ccr1,Gja1,Ccl5,Rapgef2,Cxcl2,Vasp,Ext1,Nrp2,Ddit4,Arid5b,Nr4a3,Htr2b,Il1b,Cxcl1,Vcam1,Kitl,Plat,Dnaja1,Spn,Nr4a1,Itgav,Syk,Vcan,Parp9,Phactr4,Mmp14,Fpr2,Sdc1,Cx3cl1,Cdk5r1,Nck1,Evl,Palld,Klf7,Olr1,Sdc4,Cd34,Cd80,Slc16a1,Gpc1,Tspo,Cav1,Sema3c,S100a8,Ednrb,Syne2,Slc9a1,Pstpip2,Lpar1,Itga9,Ddx4,Lyn,Sema4c,Ptk2,Egr3,Itga5,Mmp9,Lhx2,Arf4,Jak2,Fscn1,Ccl4,Ldlr,P2ry12,Hspa1a,Src,Axl,Insl6,Acvr1,Acvrl1,Fut8,Egr2,Icam1,Spata13,Hif1a,Fgr,Sell,Itga4,Ier2,Pml,Notch1,Rhoc,Hck,Cd86,Slc7a8,Tyk2,Inpp5b,Pdgfb,Scn1b,Slc7a5,Clec5a,Fpr1,Ptafr,Il12b,Cxcl10,Ptprj,Cd55,Vegfc,Plaur,Pf4,Cmklr1,Prkx,Bambi,Thbs1,Dock4,Ezr,Cx3cr1,Flt1,Sbds,Ccl12,Flrt3,Slc7a11,Sdc2,Cxcl14,Ccr3,Edn1,Il6,Pdpn,Ccl2,Ccl22,Tnfrsf14,Mark2,Atp2b4,Angpt1,Plau,Htr2a,Itgal,Il10,Ccrl2,Met,Procr,Pik3cd,Sema4a,Kpna3,Nox1,Stat1,Kif5c,Trem1,Xcr1,Socs7,Kdr |
| 2.256e-15 | -33.73 | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_DN | 162 | 47 | 15632 | 1249 |
Sla,Marcksl1,Prdm1,Carhsp1,Errfi1,Fgl2,Phf11b,Casp1,Insl6,Swap70,Ttc39c,Osbpl3,Clic4,Prkx,Ptprj,Dusp5,Serpinb9,Sap30,Phlda1,Slc4a7,Plek,Snx10,Myadm,Ccl5,Hopx,Slamf7,Cd80,Phf11a,Atp2b4,Phf11c,Chst11,Cox17,Nr4a1,Rgs1,Ccl4,Nfil3,Dgkh,Phf11d,Cysltr2,Nfkbib,Plscr1,Smpdl3b,Rap1gap2,Il18rap,S100a8,Gem,Casp4 |
| 2.402e-15 | -33.66 | WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP | MSigDB lists | WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP | 57 | 27 | 15632 | 1249 |
Gbp4,Ly75,Gbp9,Ifi44,Ctsc,Psmb9,Casp1,Plac8,Cd14,Slc16a1,Psmb10,Arg2,Socs1,Upp1,Nfkbiz,Uba7,Tap2,Ccl5,Psmb8,Sp110,Dusp28,Cmpk2,Lyn,Tlr2,Stat1,Casp7,H2-Ab1 |
| 2.421e-15 | -33.65 | regulation of transport | biological process | GO:0051049 | 1936 | 221 | 20694 | 1406 |
Clec5a,Map4k4,Casp4,Ptprj,Casp1,Hap1,Traf2,Scn1b,Rhbdf2,Gbp4,Nos2,Ripk2,Mul1,Zc3h12a,Cd300lf,Tomm70a,Notch1,Sele,Pid1,Crbn,Uaca,Frmd4a,Tlr2,Hmox1,Clec4e,Hdac1,Tnfsf4,Il10,Rab21,S100a8,Mmp13,Atp2b4,Ptger4,Abcb1a,Adora2a,Aim2,Ehd1,Rab11fip1,Tspo,Clic5,Homer1,Edn1,Stap1,Dnaja1,Nod2,Serpine1,Hvcn1,Rab9,Cd38,Stoml1,Adora2b,Cyfip1,Ptgs2,Abr,Sirt1,Mmp9,Ier3,Cd274,Acsl5,Axl,Lgals9,Il15ra,Itpr1,Htr2b,Ptch1,Rims3,Clcf1,Slc31a2,Ahr,Sdc1,Il4ra,Slc7a11,Osm,Klf7,Lyn,Cav1,Angpt1,Rab20,Rasgrp1,Ccl12,Pml,Ccr1,Ccl4,Stxbp1,Syk,Pde3b,Ccl3,Il1a,Tnf,Mapkbp1,Plk3,Rsad2,Gsdmd,Actb,Oas2,Pde4b,Lipg,Sec24b,Tlr1,C3,Cd74,Fabp3,Dync1h1,Cd40,Pfkl,Fgr,Nlgn2,Icam1,Hk1,Ccl5,Rabgef1,Irs2,Slc16a1,Hck,Src,Nr3c1,Gpr68,Cox17,Map2k1,Sec24a,Hcls1,Fpr2,Kcnj2,Arg2,Ptafr,Cxcl10,Lif,Pdgfb,Tnfsf15,Kcna3,Rnf139,Apba1,Tnfrsf1b,Clec4n,Nlrp3,Akt3,Jak2,Tlr6,Sphk1,Hmgn3,Ddx58,Cd200,Inhba,Tnfaip3,Ccl2,Tlr9,Adrb2,Slc30a1,Nfkbia,Fcgr1,Slc9a1,Scyl2,Glrx,Ezr,Mllt6,Vegfc,Mecp2,Socs1,Cxcl1,Pdgfrb,Fzd5,Htr2a,Myc,Nr1h3,Kmo,Kdm5b,Ptk2,Rhoq,Ifih1,Hspa2,Il15,Hcar2,Prnp,Cd34,Cacnb3,Thbs1,Gem,Hif1a,Il6,Cnn2,Il2rg,Ttc39b,Mdm2,Pim3,Hmga2,Il1b,Pmaip1,Trib3,Ifnar1,Itgav,Gja1,Hk2,Nr4a3,Cdk5r1,Prkce,Tnfrsf14,Serp1,Met,Rtn2,Gpr35,Sdc4,Fcgr2b,Arid5a,Pla2g4a,Siglece,Ubash3b,Mdfic,P2ry2,Cx3cl1,Cacna1d,P2ry12,Cd14,Ednrb,Agrn,Il1rn,Txn1,Stxbp3,Clic4,Rgcc,Srgn,Rab10 |
| 2.439e-15 | -33.65 | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP | MSigDB lists | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP | 116 | 39 | 15632 | 1249 |
Fpr1,H2-Ab1,Stat1,Traf3ip2,Slfn3,Vcam1,Ccl4,Slfn4,Lcp2,Snx10,Nampt,Pdk3,Ccr1,S100a8,Ccl5,Wars,Btg2,Procr,H2-Aa,Slpi,Cd74,Gbp3,Nfkbiz,Tlr6,Samhd1,Tap1,Hck,Cd14,Fcgr1,Psmb9,Msr1,Plac8,Casp1,Ccl12,Fgl2,Il18bp,Tapbp,Ctsc,Irgm2 |
| 2.501e-15 | -33.62 | regulation of anatomical structure morphogenesis | biological process | GO:0022603 | 1071 | 143 | 20694 | 1406 |
Abr,Cflar,Jag1,Ptgs2,Il6,Cyfip1,Hif1a,Itga5,Casz1,Sema4a,Ddhd1,Bmp2,Cd34,Thbs1,Plk2,Rapgef2,Il4ra,Cdk5r1,Myadm,Tnfsf14,Hk2,Tlr3,Dbnl,Rhof,Itpr1,Gja1,Ppp2r3a,Hmga2,Hhex,Il1b,Pik3r6,Sirt1,Mmp9,Fzd1,Tcf4,Il1a,Ccl3,Cx3cl1,Zswim4,Tnf,Cited2,Pde3b,Kdr,Bambi,Pml,Brwd3,Ccl12,Etv5,Col4a2,Met,Acvrl1,Rgcc,Icam1,Ccl5,Cd40,Fgr,Mtdh,Wars,Phip,C3,Mark2,Agrn,Rnd1,Il1rn,Gdf15,Bnip3,Sec24b,Lrp4,Mul1,Lpar1,Spred1,Lif,Cxcl9,Cxcl10,Flt1,Lst1,Stat2,Map2k1,Eif4g2,Sema3c,Stat3,Hck,Cdc42ep2,Src,Pgk1,Tnfaip3,Cysltr2,Hmox1,Rnd3,Pim1,Crkl,Sphk1,Bcor,Stat1,Akt3,Notch1,Rhoh,Il18,Zc3h12a,Tnfrsf1b,Ehd1,Pdpn,Rhou,Mov10,Ptger4,Vegfc,Mecp2,Znrf3,Rab21,Il10,Ezr,Cx3cr1,Acvr1,Sdc2,Ust,Adrb2,Pf4,Fmnl2,Plau,Ccl2,Cdc42ep4,Serpine1,Carmil1,Spry2,Csf1,Lrp8,Ifrd1,Klf2,Rhoq,Sema4c,Sipa1l1,Edn1,Triobp,Ptk2,Phldb1,Ccr3,Itgb8,Prag1,Rhoc,Rac3,Ccl8,Myo10,Myc |
| 2.589e-15 | -33.59 | UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN | MSigDB lists | UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN | 34 | 21 | 15632 | 1249 |
Klf2,Gem,Cited2,Nr4a1,Dusp1,Sele,Kcnj2,Zfp36,Egr2,Rcan1,Ptgs2,Nr4a3,Map3k8,Arid5b,Egr3,Atf3,Hlx,Ell2,Egr1,Cxcl1,Bmp2 |
| 2.676e-15 | -33.55 | negative regulation of protein modification process | biological process | GO:0031400 | 601 | 96 | 20694 | 1406 |
Errfi1,Bcor,Crkl,Adar,Tnfaip3,Trib1,Il18,Zc3h12a,Swap70,Pid1,Rgs14,Lif,Spred1,Mvp,Gbp4,Ptprj,Jarid2,Dusp16,Trim21,Prkar2b,Dnaja1,Dnajb2,Spry2,Ptpn2,Gadd45g,Svbp,Dtx3l,Irak3,Socs3,Atp2b4,Phactr4,Plpp3,Slfn1,Adora2a,Socs1,Tspo,Irf1,Ppp1r14b,Phlpp1,Hdac1,Ppp1r15b,Ddit4,Mllt6,Parp14,Ezr,Casp3,Psmd10,Prkce,Myadm,Ncoa7,Tnip1,Lyn,Cav1,Sirt1,Isg15,Hhex,Il1b,Trib3,Dusp1,Kdm4a,Il6,Dusp8,Cdyl,Fam129a,Dusp5,Prnp,N4bp1,Hsph1,Fam72a,Dusp2,Wars,Igf1r,Pmepa1,Rabgef1,Kat2b,Cdkn2d,Uchl1,Actb,Samsn1,Ppp1r15a,Aida,Dusp4,Gclc,Gadd45b,Spred3,Dusp6,Ubash3b,Tnf,Jun,Angpt1,Met,Nck1,Parp10,Caml,Cdkn1a,Atf3 |
| 3.033e-15 | -33.43 | WIERENGA_STAT5A_TARGETS_UP | MSigDB lists | WIERENGA_STAT5A_TARGETS_UP | 188 | 51 | 15632 | 1249 |
Vasn,Sh3bp4,Phlda1,Ddit4,Btg2,Osm,Samsn1,Klf2,Plekha4,Ccl5,Cxcl10,Arid5b,Pim1,Mob3b,Trib3,Ak4,Dusp5,Hspa2,Cish,Cst7,Slc25a37,P4ha2,Klf6,Myo10,Cd83,Nod1,Traf1,Arg2,Gbp3,Tulp3,Ch25h,Il18rap,St3gal5,Psat1,Nfil3,Rgs1,Trib1,Stap1,Il4i1,Bbx,Ccl12,Sqstm1,Gadd45b,Olr1,Tle3,Plau,Arl4a,Il4ra,Ccl22,Ccnd2,Egr1 |
| 3.033e-15 | -33.43 | GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 188 | 51 | 15632 | 1249 |
Inpp1,Cmpk2,Parp3,Trim26,Inpp5b,Tlr1,Card6,Klf2,Irf7,Nod1,Myd88,Hvcn1,Relb,Pml,Ddx58,Sell,Egr2,Treml2,Glipr2,Rsad2,Tapbp,Cst7,Klhl25,Rgs1,Cd82,Ifi35,Ptgir,Stat1,Oasl1,Cd200,Ifit3b,Sema4a,Trim14,Psme2,Slc39a14,Xaf1,Tnfrsf1b,Nfkb1,Ifit3,Slfn5,Tap1,Ddx60,Ccnd2,Parp14,Irf4,Mllt6,Gadd45g,Cnn2,Spn,Nr4a1,Gpr18 |
| 3.268e-15 | -33.35 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_UP | 182 | 50 | 15632 | 1249 |
Il1rn,Rcl1,Ldha,Map3k8,Trib3,Phlda1,Snx2,Csf3,Gja1,Tuba4a,Cd86,Traf5,Batf,Clcn5,Cd38,Mcoln2,Ier2,Hlx,Arg2,Atp11a,Spata13,Rhoq,Dusp8,Cp,Glipr2,Ccnd1,Dusp1,Ppp2r1b,Tax1bp1,Kdr,Fam162a,Casp7,Lyn,Cnn3,Hk1,Ednrb,S100a8,Lcn2,Casp4,Il10,Slc16a1,Pim3,Rbms2,Pfkfb3,Tmem176b,Gmppb,Trim13,Fpr2,Cxcl14,Ets2 |
| 3.796e-15 | -33.20 | GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN | 164 | 47 | 15632 | 1249 |
Dhx58,Rsad2,Ifi44,Rbbp8,Casp1,Ifnar1,Phf11b,Cd164,Sgk3,Isg15,Ifih1,Usp18,Slc25a12,Nmi,Tlr1,Dusp6,Gch1,Card6,Ccr1,Slc31a2,Cmpk2,Epsti1,Fmnl2,Sec24a,Slc31a1,Herc6,Parp9,Ctsc,Rnf114,Eif2ak2,Phf11c,Tap1,Prpf4,Fbxo4,Phf11a,Ddx60,Nck1,Xaf1,Plscr1,Psme2,Ifit3,Vrk2,Ifit3b,Azi2,Phf11d,Stat1,Casp7 |
| 4.006e-15 | -33.15 | immune response-activating signal transduction | biological process | GO:0002757 | 204 | 49 | 20694 | 1406 |
Cd300lf,Irak2,Zc3h12a,Mapkapk2,Lgals9,Tlr3,Crkl,Nfkbiz,Tlr6,Lcp2,Tnip1,Lyn,Themis2,Prkce,Tlr2,Nr4a3,Clec4e,Ddx58,Cacnb3,Spn,Cd38,Icosl,Fpr2,Trim12c,Cd86,Klrk1,Bcl2a1d,Irgm2,Ripk2,Tifa,Irak3,Rnf31,Pde4b,Cd14,Fpr1,Malt1,Tlr1,Ifih1,Nfkbid,Nod2,Tnip3,Dennd1b,Tlr9,Nfkbia,Myd88,Fcgr2b,Syk,Cmklr1,Tnf |
| 4.073e-15 | -33.13 | negative regulation of immune response | biological process | GO:0050777 | 155 | 42 | 20694 | 1406 |
Hmox1,Tap2,Adar,Serpinb9,Rabgef1,Nod2,Il4ra,Ifnb1,Tnfaip3,Tnfrsf14,Acod1,Tap1,Il12b,Clec2d,Dhx58,Lgals9,Parp3,Fgl2,Zc3h12a,Ptpn2,Samsn1,Irak3,Bcl6,Tnf,Abr,Hlx,Mul1,Arg2,Nlrc5,Tnfsf4,Fcgr2b,Samhd1,Trafd1,Nmi,Il10,Ccr1,Parp14,Irf1,Angpt1,Spn,Smpdl3b,Slamf8 |
| 4.156e-15 | -33.11 | GSE17721_CTRL_VS_LPS_1H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_1H_BMDC_DN | 183 | 50 | 15632 | 1249 |
Errfi1,Tpst1,Ehd1,Icam1,Ier2,Maff,Inhba,Ppp1r15a,Brwd3,Ccr1,Serpinb2,Mitd1,Arid5b,Map3k8,Fpr1,Chic2,Zc3h12a,Ripk2,Ptger4,Ifnb1,Rin2,Igsf6,Dusp2,Ccl2,Rai14,Cited2,Tiparp,Jun,Fos,Tagln,Nr4a1,Clec4e,Rnd3,Irs2,Atf3,Zfp36,Flnb,Plscr1,Procr,Zc3h12c,Cdkn1a,Tnfaip2,Cflar,Znrf1,Asb13,Ier3,Mefv,Dnajb4,Oasl1,Ebi3 |
| 4.156e-15 | -33.11 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_DN | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_DN | 183 | 50 | 15632 | 1249 |
Map4k4,Cd274,Samsn1,Csf3,Traf3ip2,Zc3h12a,Pim1,Ptgs2,Plat,Cxcl1,Snapc1,Il15ra,Slc37a3,Slc25a37,Klf6,Acpp,Itgb8,Stat3,Rab21,Hlx,Socs1,Rnd1,Tnfrsf8,Batf,Zfp319,Tnfrsf1b,P2ry2,Il10,Pdss1,Pou2f2,Stat4,Pim2,Socs3,Ier3,Tnip3,Gadd45b,Flt1,Trim36,Plac8,Gramd1a,Ptpn2,Trip10,Mrpl52,Il6,Rin2,Papss2,Fpr2,Etv3,Pfkfb3,Enpp4 |
| 4.156e-15 | -33.11 | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDC_UP | 183 | 50 | 15632 | 1249 |
Bfar,Isg15,Gbp4,Gbp9,Sat1,Oaf,Tapbp,Mdm2,Plekhf2,Rbbp8,Rgs14,Keap1,Epsti1,Dio2,Ripk2,Cdc42ep4,Tmem229b,Slamf8,Caml,Dgka,Il12rb1,Slc12a9,Cdyl,Irf7,Cd274,Klf2,Cd86,Slamf7,Pnpt1,Kif9,Hinfp,Dnase1l3,P2ry14,Arl4a,Gmppb,Pttg1,Kat2b,Ap3b1,Ptpn2,Cd300lf,Nlgn2,Lrrc8c,Ap3m2,Tnfsf4,Tlr9,Mtmr14,Acsl1,Usp12,Pla2g7,Adap2 |
| 4.250e-15 | -33.09 | positive regulation of NF-kappaB transcription factor activity | biological process | GO:0051092 | 129 | 38 | 20694 | 1406 |
Trim14,Tlr2,Traf5,Icam1,Ripk3,Cav1,Nod1,Nod2,Tlr6,Ikbkg,Nlrc4,Sphk1,Mtdh,Cd40,Tlr3,Il1b,Nlrp3,Trim13,Malt1,Il18,Irak3,Irak2,Rnf31,Tnfrsf8,Tnf,Psma6,Cx3cl1,Aim2,Eif2ak2,Ripk2,Traf1,Cflar,Traf2,Il18rap,Cx3cr1,Myd88,Stat3,Tlr9 |
| 4.427e-15 | -33.05 | regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050730 | 265 | 57 | 20694 | 1406 |
Plpp3,Vegfc,Ptger4,Syk,Bst1,Socs3,Kitl,Socs1,Tnf,Fcgr1,Hdac1,Angpt1,Irf1,Parp14,Cd40,Stap1,Nod2,Lrp8,Ccl5,Il15,Icam1,Htr2a,Ptpn2,Samsn1,Pdgfrb,Cd74,Il12b,Agrn,Il6,Pdgfb,Cd80,Lif,Itga5,Ripk2,Parp9,Lrp4,Mvp,Hsph1,Fam72a,Prnp,Src,Csf3,Hcls1,Ptprj,Rap2c,Jak2,Errfi1,Ifnar1,Lyn,Cav1,Tnfrsf14,Osm,Rictor,Prkce,Clcf1,Pdgfc,Il18 |
| 4.443e-15 | -33.05 | GO_LEUKOCYTE_ACTIVATION | MSigDB lists | GO_LEUKOCYTE_ACTIVATION | 387 | 79 | 15632 | 1249 |
Psmb10,Jmjd6,Cd74,Cd180,Icam1,Rhoh,Hhex,Itga4,Malt1,Relb,Ifna2,Ripk3,Batf,Cd40,Bcl6,Swap70,Ifnar1,Axl,Klf6,Rsad2,Treml2,Tnfsf8,Batf2,Il18,Nr4a3,Clec4d,Il12b,Ripk2,Tlr3,Ptger4,Vcam1,Plcl2,Slc7a2,Fzd5,Cd86,Lcp2,Ccl5,Ifna6,Tlr1,Stxbp3,Icosl,Cx3cl1,Egr1,Fas,Nck1,Cd80,Clec4e,Slamf7,Ifna1,Il15,Ptpn2,Jun,Syk,Spn,Cx3cr1,Ifnb1,Ifna5,Il6,Prkce,Ikzf1,Edn1,Irf4,Azi2,Lyn,Pik3cd,Sema4a,Irf1,Ebi3,Tnfsf4,Notch2,Clcf1,Casp8,Tnfsf14,Itgal,Il10,Atm,Pou2f2,Rasgrp1,Csf1 |
| 4.444e-15 | -33.05 | positive regulation of biosynthetic process | biological process | GO:0009891 | 2005 | 226 | 20694 | 1406 |
Med21,Slc9a1,Adrb2,Pf4,Tlr9,Nfkbia,Spic,Batf,Ccl2,Maml2,Mllt6,Mecp2,Rbpms,Arid4a,Cenpj,Stat5a,Ell2,Plagl1,Myc,Htr2a,Fzd5,Ptpn2,Plagl2,Dcp1a,Cebpd,Pdgfrb,Zeb1,Etv6,Fosb,Nr1h3,Spen,Klf2,Ifrd1,Csrnp1,Birc2,Rhoq,Aff1,Nupr1,Il15,Nr3c1,Egr3,Src,Stat3,Fpr2,Stat2,Tfec,Eif4g2,Hcls1,Map2k1,Klrk1,Pdgfb,Lif,Mafg,Ptafr,Wdr43,Plac8,Pou2f2,Nlrp3,Tcea1,Jak2,Tlr6,Prdx5,Stat1,Irf7,Inhba,Maff,Ddx58,Hmgn3,Nck1,Zfp281,Acvrl1,Met,Myd88,Serp1,Nampt,Etv5,Pla2g4a,Arid5a,Nlrc5,Cacybp,Egr2,Kdr,Cx3cl1,Mdfic,Ppp1r15a,Kdm6b,Agrn,Egr1,Rgcc,Lhx2,Thbs1,Prdm9,Fbxo4,Rel,Bmp2,Il6,Nfkb2,Hif1a,Acvr1b,Ciita,Tnfrsf8,Jag1,Mapkapk2,Fubp1,Tet2,Polr2g,Il1b,Hmga2,Tlr3,Ifnar1,Ikbkg,Crlf3,Pcx,Nfkb1,Relb,Nr4a3,Hdac1,Irf1,Il10,Irf2,Hinfp,Acvr1,Nr4a1,Map2k4,Ptger4,Ets2,Dtx3l,Irf4,Hivep3,Med13,Edn1,Serpine1,Hmga1,Nod2,Nsd3,Dyrk2,Icosl,Csf3,Hivep2,Ldlr,Ass1,Tnfsf8,Parp9,Nos2,Rnf14,Ythdf1,Zc3h12a,Il18,Pid1,Gfi1,Notch1,Pim1,Tlr2,Il27,Ikzf1,Atf3,Pml,Sertad3,Taf4b,Pim2,Stat4,Cited2,Syk,Bambi,Tcf4,Pcgf5,Sod2,Jun,Fzd1,Tnf,Il1a,Daxx,Ccl3,Max,Arid5b,Junb,Fabp3,Pou3f1,Cd74,Tlr1,Mycl,Mtdh,Psip1,Cd40,Larp1,Igf1r,Phip,Nox1,Dr1,Ifnb1,Irs2,Jmjd6,Kat2b,Ccl5,Icam1,Hsph1,Cd38,Spn,Plscr1,Fam129a,Adora2b,Rap2c,Nfil3,Atm,Klf6,Casz1,Bcl9,Ier2,Fos,Ptgs2,Ahrr,Arf4,Sirt1,Acsl5,Irf8,Hhex,Helz2,Htr2b,Lmo4,Ptch1,Klf7,Osm,Ncoa7,Tnip1,Pbx1,Ahr |
| 4.707e-15 | -32.99 | SMID_BREAST_CANCER_LUMINAL_B_DN | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_B_DN | 497 | 93 | 15632 | 1249 |
Slc25a37,Klf6,Ifi209,Tnc,Phgdh,Sat1,Sele,Ch25h,Cd38,Tnfaip3,Ccl5,Rcan1,Il2rg,Vcam1,Cxcl1,Plac8,Sod2,Bcl2a1b,Ass1,Gpr18,Pla2g4a,Ctsc,Stap1,Mmp14,Vcan,Dtnb,Mid1,Fas,P2ry14,Ifi214,Cx3cl1,Papss2,Col4a2,Slc16a1,Ifi207,S100a8,Cav1,Gem,Lmo4,Mndal,Ifi211,Fabp7,Isg20,Slpi,C3,Dnajb4,Ifi204,Lyn,Rbms1,Fscn1,Nfil3,Ifi213,Ifi205,Bcl2a1d,Nfkbil1,Pml,Icam1,Sell,Lad1,Ifi208,Wars,Ptger4,H2-Ab1,Slc43a3,Ptgs2,Cxcl10,Bcl2a1a,Clic4,Prkx,Igf2bp2,Abcc4,Ccl12,Tagln,Edn1,Ikzf1,Ccl2,Peli1,Pdpn,Il6,Plagl1,Rnd3,Rras2,Tap1,Angpt1,Psat1,Birc3,Marco,Ptch1,Lcn2,Ifi203,Cd69,Met,Pik3cd |
| 4.769e-15 | -32.98 | anatomical structure development | biological process | GO:0048856 | 5251 | 483 | 20694 | 1406 |
Il6,Kdm4a,Itga5,Hif1a,Vasp,Cflar,Sap30,Jag1,Thbs1,Plk2,Cd34,Sema4a,Samhd1,Gja1,Dnaaf3,Itgav,Cemip2,Casp3,Zmynd15,Relb,Ccnd1,Nr4a3,Mdm2,Clmp,Pdgfc,Palld,Fubp1,Mapkapk2,Tal2,Hmga2,Ppp2r3a,Col11a2,Kdr,Setdb2,Egr2,Kitl,Cx3cl1,Zfp281,H3f3b,Ift57,Mafk,Myd88,Serp1,Met,Arid5a,Fcgr2b,Shisa3,Ext1,Cxcl14,Eno1,Vcam1,Calcrl,Notch2,Zhx2,Rab10,Egr1,Plod3,Bcl6,Fabp7,Gdf15,Mmp25,Slc4a7,Pdlim7,Rcan1,Mark2,Rnd1,Kdm6b,Cgas,Spred3,Gadd45b,Dst,Pdgfb,Mafg,Lpar1,Batf2,Sema3c,H2-Ab1,Egr3,Plekha5,Stat3,Src,Lst1,Hcls1,4932438A13Rik,Crkl,Stat1,Bcor,Flrt3,Spint2,Adar,Maff,Ripk3,Dnase1l3,Pou2f2,Swap70,Mthfd1l,Apba1,Mecp2,Ppp2r1b,Tulp3,Vegfc,Phactr4,Znrf3,Hopx,Slc9a1,Apaf1,Spic,Bbx,Ezr,Ddit4,Sdc2,Klf2,Ntng2,Triobp,Csrnp1,Birc2,Spry2,Myc,Plagl2,Ppp4r2,Dync1i2,Zeb1,Atm,Nes,Mturn,Fos,Abr,Bcl2a1d,Cd38,Timeless,Slc39a13,Cdyl,Adgrl2,Ptch1,Lmo4,Htr2b,Chst11,Atp11a,Lyn,Slc7a11,Kremen1,Sdc1,Ahr,Clcf1,Arf4,Csrp1,Fam20c,Txnrd1,Hp,Axl,Irf8,Gpsm2,Pik3r6,Hhex,Syk,Pde3b,Sod2,Fzd1,Zswim4,Snx2,Ccl3,Ifi204,Prdm1,Col4a2,Pml,Ccr1,Ciapin1,Eya4,Fgr,Ankrd17,Igf1r,Fndc3a,Wars,Nox1,Tshz1,Ifnb1,Ccl5,Sec24b,Actb,Malt1,Junb,C3,Cd74,Scn1b,Spred1,Htra1,Ifna4,Tab2,Nos2,Map4k4,Csf3,Icosl,Ptprj,Tlk2,Tnfsf8,Tdrd7,Flnb,Gsta3,Clec4e,Tlr2,Clec4d,Hmox1,Tiparp,Cd300lf,Pid1,Rhoh,Notch1,Abcb1a,Ptger4,Mov10,Mmp13,Ets2,Ehd1,Adora2a,Rnf114,Hdac1,Ust,Adgrg6,Adam19,Plau,S100a8,Nr4a1,Hinfp,Plaur,Acvr1,Tnfsf4,Xkr8,D16Ertd472e,Tent2,Tsku,Stap1,Homer1,Serpine1,Adap2,Flrt2,Lrp8,H2-Q7,Gadd45g,Zfp36,Morc3,Itgb8,Clic5,Nectin2,Hivep3,Nfkb2,Acvr1b,Ttc39c,Cnn2,Phgdh,Lox,Nrp2,Lhx2,Tnfsf9,Casp2,Bmp2,Nfkb1,Rcn1,Keap1,Cdk5r1,Btg2,Ifna1,Acp5,Tet2,Diaph2,Il1b,Acp2,Cacybp,Sik3,Inpp5b,P2ry12,P2ry2,Ifna6,Nck1,Acvrl1,Phf6,Cdkn1a,Rbbp8,Pikfyve,Casp8,Zfp513,Katna1,Pla2g4a,Gys1,Etv5,Vezt,Sdc4,Mosmo,Clic4,Stxbp3,Tmem67,Slc7a5,Srgn,Ifitm1,Ednrb,Psmb10,Agrn,Il12b,Slc25a25,Lif,Flt1,Arg2,Vcan,Heatr9,Psma6,Gpc1,Nr3c1,Bcl2l11,Odc1,Fpr2,Snx10,Eif4g2,Map2k1,Dock10,Rap1gap2,Sphk1,Tcea1,Jak2,Errfi1,Inhba,Tnfaip3,Rictor,Tnfrsf1b,Rgs14,Akt3,Azi2,Golga3,Herc6,Apobec3,Kif5c,Ifna2,Tnc,Arid4a,Socs3,Stat5a,Pdpn,Pnpt1,Plagl1,Med21,Slamf8,Slc30a1,Evl,Ccl2,Batf,Antxr1,Hspa2,Spen,Ifrd1,Sipa1l1,Igsf9,Col18a1,Csf1,Nupr1,Il15,Cebpd,Pdgfrb,Ptpn2,Fzd5,Ptk2,Prag1,Prkx,Etv6,Rac3,Kdm5b,Nr1h3,Tle3,Ddx4,Cyfip1,Casz1,Bcl9,Syne2,Mmd,Ier2,Ptgs2,Mgat1,Rapgef2,Spn,Plscr1,Tpi1,Rap2c,Marf1,Dbnl,Tagln,Itpr1,Acod1,Tmeff1,Samd9l,F11r,Klf7,Cav1,Osm,Myadm,Pbx1,Spire1,Plcl2,Mmp9,Sirt1,Il15ra,Cd164,Cited2,Stxbp1,Tcf4,Jun,Rsad2,Tnf,Il1a,Angpt1,Ikzf1,Atf3,Ccl12,Taf4b,Nlgn2,Mycl,Psd,Uchl1,Jmjd6,Irs2,Kat2b,Icam1,Rpgrip1l,Col27a1,Aida,Arid5b,Insl6,Pou3f1,Tnfaip2,Mthfr,Rilpl1,Ifna5,Lrp4,Mul1,Hlx,Stk40,Gpd2,Tmod3,Serpinb6b,B3gnt5,Casp4,Tut7,Hsd17b7,Clec5a,Micall2,Hap1,Casp1,Jarid2,Ldlr,Rrs1,Foxp4,Sbds,Gpr18,Sgcb,Zc3h12a,Il18,Prokr1,Trip10,Gfi1,Scarf1,Plpp3,Cenpe,Lnpk,Kif3c,Tspo,Irf1,Dach1,Cx3cr1,Rab21,Asf1a,Il10,Cnp,Intu,Map2k4,Socs7,Trip13,Edn1,Sema4c,Frmd6,Papss2,Fas,Itga4,Irf4,Mmp14,Sav1,Casp7,Ccr3 |
| 5.042e-15 | -32.92 | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP | 159 | 46 | 15632 | 1249 |
Evl,Egr1,Il4ra,Irs2,Pikfyve,Traf5,Rras2,Cd83,Ciita,Zbp1,Ezr,Cnn2,Bcl2a1b,Plekhf2,Sp140,Gpr18,Swap70,Jun,Fcgr2b,Peli1,Rhoq,Myc,Aftph,Stap1,Bcl2a1d,Ift57,Cd55,Cd200,Mob3b,Arid5b,Bcl2a1a,Clic4,Birc3,Junb,4930523C07Rik,Atm,Tuba4a,Klf2,Casp4,Sipa1l1,Plekha2,Ampd3,Snx2,Usp12,Hk2,Cd69 |
| 5.227e-15 | -32.88 | GO_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | 50 | 25 | 15632 | 1249 |
Ifi204,Serpinb9,Trafd1,Mndal,Ifi203,Ifi211,Ifi208,Nmi,Ifi214,Nr1h3,Mul1,H2-Q7,Ifi207,Irak3,Tnfaip3,Tap1,Adar,H2-Q6,Ifi209,Ptpn2,Ifi205,H2-Q4,Nlrc5,Ifi213,Dhx58 |
| 5.598e-15 | -32.82 | GO_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION | 230 | 57 | 15632 | 1249 |
H2-Q4,Spn,Syk,Ccl12,Cited2,Il6,Nod2,Ap3b1,Nck1,Il4ra,Cx3cl1,Nlrp3,Il15,Cd80,Tnfrsf14,Cav1,Tnfsf14,Rictor,Rasgrp1,Ebi3,Tnfsf4,Egr3,Lyn,Src,Hsph1,Tnf,Traf2,H2-Q6,Pnp2,Hlx,Itga4,H2-Q7,Malt1,Cd74,Cd83,Ccdc88b,Myo10,H2-Eb1,Ccl5,Cd86,Cd274,Pik3r6,Icosl,H2-Aa,Piezo1,Il12rb1,Cd55,H2-Ab1,Ripk2,Ptafr,Il18,Map3k8,Il12b,Nr4a3,Vcam1,Gcnt2,Il1b |
| 6.085e-15 | -32.73 | MODULE_64 | MSigDB lists | MODULE_64 | 499 | 93 | 15632 | 1249 |
Sla,Cd14,H2-Q6,Csf3r,Slc16a3,Tnc,Il2rg,Map3k8,Tlr3,Il1b,Htr2b,Cxcl1,Osm,H2-Eb1,Ccr1,Gja1,Dusp6,Inhba,Fpr2,Cx3cl1,P2ry14,Cdk5r1,Fas,Hk3,Ahr,Olr1,Il15,Spn,Mmp14,Dusp2,Lpar1,Ptgir,C3,Cdkn1a,Ccl4,Ldlr,Cd82,Cav1,Tnfrsf1b,Ednrb,Csf1,Calcrl,Stat2,Icam1,Il1a,Fgr,Sell,H2-Q7,Lif,Cd83,Bmp2,Cd40,Axl,Gypc,Fpr1,Ptafr,Cxcl10,Cd55,Dusp5,Plaur,Il15ra,Pf4,Tnfsf10,Cd86,Nampt,Csf3,Pdgfb,Tlr1,Il4ra,Pfkfb3,Fcgr1,Gng11,Htr2a,H2-Q4,Cx3cr1,Flt1,Ccl12,Cxcl14,Kcnj2,Il6,Pdpn,Ccl2,Igsf6,Adrb2,Tlr2,Tnfsf4,Stat1,Gna15,Tnfsf14,Itgal,Jag1,Stat4,Cd69 |
| 6.484e-15 | -32.67 | positive regulation of cellular catabolic process | biological process | GO:0031331 | 357 | 68 | 20694 | 1406 |
Nupr1,Nod2,Dnajb2,Irs2,Nod1,Trim21,Tmem67,Mtdh,Larp1,Gclc,Mefv,Rnf19b,Cop1,Ptk2,Zfp36,Myc,Bnip3,Dtx3l,Htr2a,Tnf,Plk3,Pnpt1,Hspa1a,Kdr,Plekhn1,Sh3bp4,Mov10,Pim2,Ezr,Irgm1,Tlr9,Rnf19a,Adrb2,Hmox1,Psmd10,Tlr2,Tnfaip3,Trib1,Ikbkg,Hk2,Il1b,Trib3,Zc3hav1,Trim13,Polr2g,Acsl5,Zc3h12a,Tnfrsf1b,Rnf139,Sirt1,Optn,Btg2,Mdm2,Rnf14,Ankib1,Mul1,Ripk2,Irgm2,Sesn3,Hif1a,Il6,Atm,Ctsc,Ldlr,Map2k1,Bcl2l11,Hspa1b,Plk2 |
| 6.540e-15 | -32.66 | GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_UP | MSigDB lists | GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_UP | 160 | 46 | 15632 | 1249 |
Ccl4,Gbp2b,Rgs1,Nfil3,Ell2,Odc1,Phf11d,Plscr1,Cysltr2,Il18rap,Smpdl3b,Dach1,S100a8,Gem,Tnfsf14,Gna15,Phf11a,Phf11c,Atp2b4,Pttg1,Fcgr2b,Cpd,Cx3cr1,Gadd45b,Zyx,Prkx,Dusp5,Ptprj,Ttc39b,Serpinb9,Phlda1,Myadm,Snx10,Slc4a7,Hopx,Irak3,Cd38,Prdm1,Hif1a,Carhsp1,Fgl2,Arhgap26,Casp1,Insl6,Cst7,Phf11b |
| 6.563e-15 | -32.66 | MITSIADES_RESPONSE_TO_APLIDIN_UP | MSigDB lists | MITSIADES_RESPONSE_TO_APLIDIN_UP | 382 | 78 | 15632 | 1249 |
H3f3b,Rpgrip1l,Rbms1,Arf4,Idi1,Ldlr,Trib1,Irf1,Etnk1,Oasl1,Oas1a,Ksr1,Isg20,St3gal5,Plscr1,Sik3,Gem,Tor3a,Prpf4,Tle3,Pfkfb3,Pde3b,Nxf1,Irs2,Ifrd1,Ift57,Stap1,Dusp2,Tgs1,Jun,Nfkbia,Flt1,Gadd45b,Ifit1bl1,Morc3,Ezr,Rnf114,Trmt1l,Bcl2l11,Sqstm1,Tnfsf10,Cldnd1,Phyh,Nr4a3,Arid5b,Kdm6b,Fam53c,Dusp5,Oas1g,Rapgef2,Maff,Pdgfb,Ext1,Phlda1,Klf2,Samsn1,Ppp1r15a,Irf7,Fosb,Nampt,Jarid2,Ifit1bl2,Brd2,Dusp6,Icam1,Kmo,Socs1,Arg2,Jmjd6,Rab9,Egr2,Mtus1,Timp1,Armcx6,Parp8,Dusp1,Klf6,Src |
| 6.659e-15 | -32.64 | locomotion | biological process | GO:0040011 | 1169 | 151 | 20694 | 1406 |
Cxcl11,Sdc1,Nr4a3,Cdk5r1,Klf7,Sell,Itgav,Htr2b,Gja1,Ptch1,Rhof,Asap3,Plat,Il1b,Lgals9,Axl,Palld,Arf4,Ccl22,Saa3,Lox,Syne2,Vasp,Ier2,Hif1a,Ddx4,Cyfip1,Sema4a,Trem1,Nrp2,Thbs1,Pik3cd,Rapgef2,Lhx2,Cd34,Spn,Ccl5,Cxcl2,Icam1,Nox1,Ext1,Cxcl14,Vcam1,Nlgn2,Fut8,Agrn,Il12b,Il1rn,Mark2,Rcan1,Ednrb,Actb,Fpr1,Pde4b,Fscn1,Arid5b,Insl6,Cx3cl1,Tnf,Ccl3,Inpp5b,Kitl,P2ry12,Ccl4,Kdr,Egr2,Bambi,Syk,Katna1,Ccl12,Sdc4,Abcc1,Pml,Ccr1,Spata13,Acvrl1,Gpr35,Angpt1,Met,Nck1,Pstpip2,Sbds,Tnfaip3,Cxcl3,Flrt3,Crkl,Notch1,Sele,Itga9,Gpc1,Lpar1,Cxcl10,Flt1,Ptafr,Vcan,Scn1b,Cxcl9,Pdgfb,Ptprj,Map2k1,Pvr,Fpr2,Xcr1,Egr3,Src,Sema3c,Lrp8,Dock4,Carmil1,Flrt2,Ntng2,Csf3r,Ccrl2,Sema4c,Socs7,Dnaja1,Itgb8,Prag1,Rhoc,Ch25h,Prkx,Rac3,Ccl9,Ccr3,Ptk2,Mmp14,Pdgfrb,Ccl8,Myo10,Itga4,Pdpn,Ccl7,Tspo,Cxcl1,Cmklr1,Kif5c,Mcoln2,Atp2b4,Phactr4,Vegfc,Ddit4,Nr4a1,Sdc2,Acvr1,Cx3cr1,S100a8,Ccl2,Plau,Slamf8,Pf4,Evl |
| 6.682e-15 | -32.64 | GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_DN | MSigDB lists | GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_DN | 185 | 50 | 15632 | 1249 |
Il15ra,Rcl1,Bcl2a1a,Cxcl1,Clec4d,Cdc42ep4,Ptger4,Mmp13,Cxcl2,Hk2,Phlda1,Gch1,Atp11a,Il1a,Traf1,Mcoln2,Mdm2,Ccng2,Prdx5,Bcl2a1d,Dusp1,Ehd1,Klf6,Tnf,Dync1h1,Dusp16,Hsd17b7,Rbms1,Arf4,Tax1bp1,Tnip1,Zc3h12c,Il10,Mov10,Cep350,Clec4e,Fpr2,Nr1h3,Egr1,Ifrd1,Tor1aip2,Dusp2,Il4i1,Peli1,Cyfip1,Cited2,Nr4a1,Gadd45b,Bcl2a1b,Bcl2l11 |
| 7.222e-15 | -32.56 | GSE30083_SP1_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP4_THYMOCYTE_DN | 179 | 49 | 15632 | 1249 |
Ifih1,Dtx3l,Traf5,Nod1,Myd88,Crlf3,1600014C10Rik,Rab3ip,Hvcn1,Dpy19l1,Dse,Tbc1d1,Stat3,Rab21,Rhoq,Ifi44,Ly75,Tnfsf8,Herc6,Oas1g,Traf3ip2,Ttc39b,Ikbke,Trafd1,Klf2,Irf7,Tlr1,Oas2,Ubash3b,Pde3b,Atp11b,Tap1,Nlrc5,Spn,Klf3,Irgm2,Cd200r4,Samd9l,Endod1,Oasl1,Ms4a6d,Clcf1,Adam19,Gbp7,Plekha2,Ampd3,Oas1a,Syne2,Tdrd7 |
| 7.586e-15 | -32.51 | FEVR_CTNNB1_TARGETS_UP | MSigDB lists | FEVR_CTNNB1_TARGETS_UP | 633 | 109 | 15632 | 1249 |
Junb,Maff,Dgka,Oas2,Btg2,Ttc39b,Tgfbi,Pim1,Oas1g,Smox,Cmpk2,Gng12,Slc2a1,Hspa1a,Src,Dusp1,Gsr,Dusp8,Casp3,Sphk1,Stat2,Hif1a,Relb,Hck,Ifit1,Casp4,Ifit3,P4ha1,Clic5,Oas1a,Rnf19a,Procr,Gpd2,Irf1,Socs3,Stat1,Il13ra1,Ap3m2,Gfi1,Socs7,Agpat4,Cacna1d,Zyx,Jun,Fos,Triobp,Gpr35,Abcb1a,Sgms2,Atf3,Abr,Samhd1,Tap1,Mark2,Gclc,Cdc42ep2,Zbp1,Ciita,Pdgfrb,Irf7,Tap2,Ccl5,Dusp6,Igsf9,Plek,Bst1,Car13,H2-Aa,Trim26,Nrp2,Slc31a1,Hp,Gtpbp2,Bcl6,Serp1,Dhx58,Rab21,D1Ertd622e,Stat3,F11r,Upp1,Usp18,Csrnp1,Mvp,Tnfaip3,Plekhg1,Syne2,Egln3,Pstpip2,Ifit3b,Rab20,Oasl1,C3,Hmgcs1,Dnajb2,Hsd17b7,Cdkn1a,Jak2,Rnf114,Klf3,Gadd45b,Gadd45g,Optn,Stxbp1,Ddx60,Atp11b,Me1,Klf7,Il15 |
| 8.327e-15 | -32.42 | system development | biological process | GO:0048731 | 4277 | 408 | 20694 | 1406 |
Ifna4,Nos2,Tab2,Scn1b,Spred1,Htra1,Ptprj,Tnfsf8,Map4k4,Icosl,Csf3,Clec4e,Clec4d,Hmox1,Tlr2,Flnb,Tdrd7,Gsta3,Rhoh,Notch1,Tiparp,Cd300lf,Ehd1,Adora2a,Mov10,Ptger4,Mmp13,S100a8,Acvr1,Plaur,Nr4a1,Tnfsf4,Hdac1,Ust,Adgrg6,Adam19,Plau,Adap2,Serpine1,Flrt2,Lrp8,Tent2,D16Ertd472e,Stap1,Tsku,Homer1,Clic5,Itgb8,Hivep3,Gadd45g,Mturn,Bcl2a1d,Fos,Abr,Atm,Nes,Adgrl2,Cd38,Timeless,Lyn,Chst11,Kremen1,Slc7a11,Ahr,Clcf1,Ptch1,Htr2b,Lmo4,Hp,Gpsm2,Axl,Irf8,Pik3r6,Hhex,Fam20c,Arf4,Sod2,Fzd1,Zswim4,Ifi204,Ccl3,Syk,Pde3b,Ccr1,Ciapin1,Pml,Eya4,Prdm1,Col4a2,Ifnb1,Ccl5,Ankrd17,Fgr,Igf1r,Fndc3a,Tshz1,Wars,Nox1,Cd74,C3,Sec24b,Actb,Malt1,Junb,Lpar1,Batf2,Dst,Pdgfb,Lst1,Hcls1,4932438A13Rik,Sema3c,Plekha5,H2-Ab1,Egr3,Src,Stat3,Maff,Adar,Ripk3,Crkl,Flrt3,Stat1,Bcor,Spint2,Pou2f2,Swap70,Mthfd1l,Hopx,Mecp2,Phactr4,Tulp3,Vegfc,Bbx,Sdc2,Ddit4,Slc9a1,Apaf1,Spry2,Klf2,Triobp,Csrnp1,Ntng2,Birc2,Ppp4r2,Dync1i2,Zeb1,Myc,Vasp,Cflar,Sap30,Jag1,Il6,Kdm4a,Hif1a,Sema4a,Samhd1,Plk2,Thbs1,Cd34,Relb,Ccnd1,Nr4a3,Casp3,Dnaaf3,Cemip2,Itgav,Gja1,Mapkapk2,Fubp1,Tal2,Hmga2,Ppp2r3a,Mdm2,Clmp,Pdgfc,Palld,Kitl,Cx3cl1,Col11a2,Kdr,Egr2,Arid5a,Fcgr2b,H3f3b,Ift57,Mafk,Met,Serp1,Calcrl,Zhx2,Notch2,Egr1,Rab10,Cxcl14,Ext1,Vcam1,Rcan1,Mark2,Kdm6b,Rnd1,Plod3,Bcl6,Fabp7,Slc4a7,Pdlim7,Hlx,Mul1,Lrp4,Stk40,Gpd2,Serpinb6b,Tmod3,Mthfr,Ifna5,Hap1,Micall2,Jarid2,Ldlr,Rrs1,B3gnt5,Hsd17b7,Clec5a,Sbds,Gpr18,Foxp4,Prokr1,Trip10,Gfi1,Scarf1,Sgcb,Zc3h12a,Il18,Tspo,Plpp3,Kif3c,Cx3cr1,Cnp,Rab21,Il10,Intu,Map2k4,Irf1,Papss2,Fas,Socs7,Edn1,Sema4c,Mmp14,Sav1,Casp7,Ccr3,Itga4,Irf4,Mmd,Bcl9,Syne2,Ier2,Ptgs2,Cyfip1,Casz1,Rapgef2,Spn,Plscr1,Cav1,Klf7,Osm,Pbx1,Spire1,Dbnl,Samd9l,Acod1,Tmeff1,Itpr1,Il15ra,Cd164,Plcl2,Sirt1,Mmp9,Tcf4,Jun,Rsad2,Tnf,Il1a,Cited2,Stxbp1,Atf3,Ccl12,Ikzf1,Angpt1,Uchl1,Irs2,Kat2b,Jmjd6,Icam1,Mycl,Nlgn2,Psd,Pou3f1,Tnfaip2,Col27a1,Rpgrip1l,Insl6,Arid5b,Heatr9,Gpc1,Psma6,Slc25a25,Lif,Flt1,Vcan,Arg2,Fpr2,Odc1,Snx10,Eif4g2,Dock10,Map2k1,Nr3c1,Bcl2l11,Tnfaip3,Inhba,Sphk1,Rap1gap2,Tcea1,Jak2,Errfi1,Rgs14,Akt3,Tnfrsf1b,Stat5a,Pdpn,Plagl1,Azi2,Herc6,Kif5c,Apobec3,Ifna2,Arid4a,Tnc,Socs3,Slamf8,Evl,Batf,Ccl2,Col18a1,Igsf9,Nupr1,Csf1,Il15,Antxr1,Spen,Ifrd1,Sipa1l1,Ptk2,Etv6,Prkx,Rac3,Kdm5b,Prag1,Fzd5,Ptpn2,Pdgfrb,Cebpd,Cnn2,Ttc39c,Lox,Phgdh,Nfkb2,Acvr1b,Bmp2,Lhx2,Nrp2,Tnfsf9,Nfkb1,Cdk5r1,Rcn1,Tet2,Il1b,Acp2,Btg2,Ifna1,Acp5,P2ry12,P2ry2,Cacybp,Sik3,Cdkn1a,Zfp513,Casp8,Pikfyve,Etv5,Gys1,Pla2g4a,Katna1,Sdc4,Nck1,Ifna6,Acvrl1,Slc7a5,Srgn,Clic4,Mosmo,Stxbp3,Tmem67,Il12b,Agrn,Ednrb |
| 8.463e-15 | -32.40 | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | MSigDB lists | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | 161 | 46 | 15632 | 1249 |
Cox17,Chst11,Nr4a1,Cx3cr1,Spn,Zyx,Slamf7,Phf11a,Phf11c,Atp2b4,Pttg1,Nfkbib,Plscr1,Cysltr2,Rap1gap2,Il18rap,Smpdl3b,S100a8,Gem,Itgal,Gna15,Gbp2b,Rgs1,Ccl4,Nfil3,Dgkh,Phf11d,Carhsp1,Insl6,Casp1,Phf11b,Ttc39c,Sla,Prdm1,Ier2,Phlda1,Sap30,Myadm,Ccl5,Slc4a7,Plek,Snx10,Dusp5,Ptprj,Serpinb9,Ttc39b |
| 8.578e-15 | -32.39 | molecular function regulator | molecular function | GO:0098772 | 1730 | 204 | 20217 | 1400 |
Gpsm2,Dnaja2,Rgs1,Socs1,Prkce,Csf1,Bmp2,Cav1,Stoml1,Prdx5,Tnfsf15,Pik3r6,Il10,Cxcl9,Rgl1,Flrt3,Ccl4,Inhba,Slpi,Cx3cl1,Sipa1l1,Elmod2,Il1b,Serpina3g,Ifna6,Dnajb2,Osm,Atp2b4,Ccl12,Adap2,Mmp25,Ppp1r15b,Sgk3,Cdkn2d,Ppp1r14b,Ifna2,Crim1,Cxcl1,Ctla2b,Itpr1,Abr,Il12b,Rcan1,Il15,Rab3ip,Rgs3,Ccl22,Ppp1r12b,Sema4a,Cxcl14,Nck1,Rin2,Hsph1,Trib3,Ccl3,Ccne1,Vegfc,Tnfsf14,Dennd2a,Serpinb2,Socs3,Birc3,Serpina3f,Cst7,Ppp2r3a,Kitl,Serpine1,Birc2,Tnfsf10,Gdf15,Sh3bp4,Il1rn,Clcf1,Tbc1d13,Nampt,Ctsc,Gclm,Ikbke,Tbc1d1,Ppp2r5a,Ralgds,Cxcl10,Ppp4r2,Rap1gap2,Insl6,Rgcc,Cxcl11,Spred1,Rgs14,Ifna1,Rapgef5,Ppp1r15a,Ccng2,Kat2b,Map2k1,Wfdc17,Ccl5,Jag1,Malt1,Dnaja1,Nsmaf,Ebi3,Htr2b,Cflar,Adrb2,Serpinb6b,Tor1aip1,Dnajb4,Serpinb9b,Ccnj,Arhgef3,Cxcl2,C3,Dock10,Pik3r5,Cacnb3,Apaf1,Ccnd1,Trib1,Sema4c,Ahsa1,Mtcp1,Irgm2,Dock4,Wars,Ppp2r1b,Gem,Slc30a1,Cdkn1a,Psd,Tagap,Bcl2a1d,Timp1,Tor1aip2,Tnf,Ripk3,Tank,Rictor,Cxcl3,Dtx3l,Parp9,Ric1,Tnfsf9,Cdk5r1,Edn1,Nupr1,Ccl7,Serpinb9,Ccl9,Scn1b,Rhoh,Cox17,Psme1,Spint2,Ifnb1,Pttg1,Il18,Rapgef2,Dennd6b,Rabgef1,Osgin2,Daxx,Cdc42ep2,Ccl8,Psme2,Ccl2,Lif,Psd4,Pf4,Cyth3,Il27,Cish,Dennd1b,Ranbp2,Tnfsf4,Il1a,Prkar2b,Pdgfb,Arhgap26,Dcp1a,Ifna4,Il6,Saa3,Casp3,Jun,Ifna5,Phactr4,Agrn,Pdgfc,Ppp2r2a,Notch1,Asap3,Ccnd2,Tnfsf8,Cd55,Nos2,Sema3c,Lgals9,Rasgrp1,Spata13,Spry2,Csf3,Socs7,Flrt2 |
| 8.766e-15 | -32.37 | GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 446 | 86 | 15632 | 1249 |
Pim1,Adora2b,Map3k8,Fpr1,Crkl,Tlr3,Dusp5,Ripk2,Il1b,Htr2b,Pilrb1,Thbs1,Irak2,Kitl,Lcp2,Fzd5,Map2k1,Pdgfrb,Pik3r6,Txn1,Dusp6,Ccl5,Rapgef2,Pdgfb,Tnfsf15,Tab2,Cd74,Fgr,Malt1,Daxx,Ripk3,Pdgfc,Mdfic,Nod1,Bmp2,Traf2,Cd40,Src,Hsph1,Tnf,Ccnd1,Hspa2,Dbnl,Lpar1,Adrb2,Lyn,Acsl1,Ptk2,Tlr9,Cdkn1a,Prkar2b,Jak2,Lmo4,Ikbkg,Sirt1,Mmd,Rasgrp1,Csf1,Ccnd2,Cdk5r1,Mul1,Tpx2,Mapkapk2,Tlr6,Lrp8,Atp2b4,Mark2,Angpt1,Sdc4,Pilrb2,Htr2a,Psmd10,Flt1,Gadd45b,Eif2ak2,Map3k6,Cenpe,Syk,Pik3r5,Nod2,S1pr2,Pde5a,Gadd45g,Edn1,Spry2,Stap1 |
| 9.173e-15 | -32.32 | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP | 180 | 49 | 15632 | 1249 |
Rab20,Ell2,Ebi3,Pmepa1,Abcc1,Rgs1,Casp4,Gem,Il10,Jdp2,Smpdl3b,Psme2,Tmtc2,Ahr,Dusp14,Dnase1l3,Hk3,Bcl2a1b,Spsb1,Chst11,Tapbpl,Adora2b,Dusp5,Rnf19b,Xkr8,5430427O19Rik,Glrx,Tnfsf10,Bcl2a1a,Asns,Samsn1,Slc4a7,Stx11,Ppp2r3a,Il12rb1,Psmb10,Prdm1,Myo10,Plagl2,Mgat1,Itpr1,Cst7,Ehd1,Bcl2a1d,Mlkl,Cdyl2,Fchsd2,Slc39a4,Stat3 |
| 9.173e-15 | -32.32 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_DN | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_DN | 180 | 49 | 15632 | 1249 |
Src,Hivep2,Spsb1,Sod2,Bcl2l11,Slc7a11,Dock4,D16Ertd472e,Fcgr2b,Rab21,Rnf24,Nod2,Cpd,Fpr2,Ifih1,Sphk1,Nlrp3,Sertad3,Notch1,Daxx,Zc3hav1,Plagl2,Tnfrsf1b,Gch1,Ppp1r15a,Irf7,Plscr1,Scn1b,Zfp36,Wars,Pla2g7,Rnf19a,Il18rap,Cxcl2,Cd69,Tdrd7,Ell2,Zc3h12a,Chic2,Itga9,Serpinb9,Ier3,Map3k8,Zcchc2,Cflar,Tnfsf10,H3f3b,Glrx,Keap1 |
| 9.181e-15 | -32.32 | GO_POSITIVE_REGULATION_OF_CELL_ADHESION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_ADHESION | 354 | 74 | 15632 | 1249 |
Tnfrsf14,Angpt1,Il15,Sdc4,Cd80,Cyth3,Nlrp3,Cx3cl1,Il4ra,Nck1,Ap3b1,Nod2,Triobp,Prkce,Il6,Cited2,H2-Q4,Spn,Syk,Ccl12,Itgav,Jak2,Kdr,Lyn,Egr3,Tnfsf4,Ebi3,Rac3,Itga5,Rictor,Rasgrp1,Csf1,Tnfsf14,Cav1,Plekha2,Myo10,Cd83,Ccdc88b,Cd74,Malt1,H2-Q7,Itga4,Hlx,Pnp2,H2-Q6,Traf2,Src,Hsph1,Tnf,Vegfc,Il1b,Vcam1,Gcnt2,Nr4a3,Il12b,Ptafr,Il18,Map3k8,H2-Ab1,Ptger4,Ptprj,Cd55,Ripk2,Il12rb1,Icosl,Piezo1,H2-Aa,Cd274,Cd86,Pik3r6,Hsd17b12,H2-Eb1,Myadm,Ccl5 |
| 9.337e-15 | -32.30 | response to lipid | biological process | GO:0033993 | 749 | 110 | 20694 | 1406 |
Lgals9,Mapkapk2,Axl,Irf8,Il1b,Cd274,Acp5,Lyn,Cav1,Nfkb1,Ahr,Cxcl11,Prkce,Nr4a3,Acod1,Ptch1,Ifnar1,Cd86,Plscr1,Cflar,Abr,Ptgs2,Lox,Atm,Il6,Slpi,Cd80,Cd180,Il1rn,Il12b,Pde4b,Malt1,Ednrb,Cd14,Junb,Ifnb1,Cdkn2d,Cxcl2,Ccl5,Tnip3,Mtdh,Ccl12,Arid5a,Gch1,Myd88,Noct,Jun,Tnf,Daxx,Gramd1a,Pid1,Gfi1,Nlrp3,Irak2,Tnfrsf1b,Zc3h12a,Il18,Tnfaip3,Trib1,Inhba,Cxcl3,Pim1,Tlr2,Nfkbib,Jak2,Stat1,Cmpk2,Casp1,Ldlr,Pdk3,Ass1,Map2k1,Nr3c1,Nfkbil1,Peli1,Src,Stat3,Lpar1,Ripk2,Irgm2,Tab2,Nos2,Klrk1,Cxcl9,Cxcl10,Ptafr,Ptgir,Nr1h3,Irak3,Fcgr4,Pdgfrb,Zfp36,Serpine1,Nod2,Fas,Dnaja1,Stap1,Cx3cr1,Il10,Nr4a1,Ddit4,Glrx,Tnfsf4,Gbp2,Nfkbia,Pf4,Ccl2,Cxcl1,Eif2ak2,Ptger4 |
| 9.672e-15 | -32.27 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP | 193 | 51 | 15632 | 1249 |
Parp9,Pilrb2,Cdc42ep2,Rbl1,Samhd1,Ccnd2,Prnp,Cysltr2,Trim14,Slpi,Etv6,Rabgef1,Birc3,P4ha1,Cflar,Max,Dram1,Ifi35,Dtx2,Oasl1,Stat1,Setdb2,Ifi44,Insl6,Clmp,1600014C10Rik,Ifit1,Hck,Relb,Jmjd6,Socs1,Dtx3l,Sap30,Slc7a5,Nmi,Cxcl2,AA467197,Samsn1,Tor1aip1,Slfn4,Ppm1k,Osm,Vps54,Pilrb1,Slfn3,Tnfsf10,Clic4,Pcgf5,Clec5a,Trib3,Cox18 |
| 9.952e-15 | -32.24 | BURTON_ADIPOGENESIS_PEAK_AT_2HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_2HR | 47 | 24 | 15632 | 1249 |
Thbs1,Pim1,Dnajb4,Ptgs2,Ier3,Btg2,Zfp36,Phlda1,Hk2,Junb,Tnfrsf1b,Sema3c,Ppp1r15a,Fosb,Serpine1,Il6,Myc,Errfi1,Cebpd,Gadd45g,Dusp1,Nr4a1,Fos,Ets2 |
| 9.952e-15 | -32.24 | GO_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | 47 | 24 | 15632 | 1249 |
Ifi214,Nlrp3,Sphk1,Aim2,Pml,Ifi207,Tnfaip3,Nod1,Ifi205,Ifi209,Ifi213,Gsdmd,Casp1,Ifnar1,Errfi1,Nod2,Ifi204,Mefv,Zc3h12a,Jak2,Mndal,Ifi203,Ifi211,Ifi208 |
| 1.004e-14 | -32.23 | regulation of ERK1 and ERK2 cascade | biological process | GO:0070372 | 310 | 62 | 20694 | 1406 |
Cd74,C3,Ccl9,Ccl8,Dusp4,Htr2a,Ptpn2,Pdgfrb,Spry2,Notch2,Nod1,Nod2,Ccl5,Icam1,Atf3,Ccr1,Ezr,Ccl12,Rasgrp1,Phlpp1,Ccl2,Angpt1,Jun,Glipr2,Cx3cl1,Ccl3,Ccl7,Il1a,Syk,Dusp6,Kdr,Ccl4,Rgs14,Il1b,Notch1,Scimp,Ccl22,Pdgfc,Cav1,Lyn,Tnip1,Cysltr2,Tlr2,Clcf1,Crkl,Htr2b,Errfi1,Marco,Fpr2,Bmp2,Map2k1,Rapgef2,Src,Gcnt2,Ripk2,Cflar,Il6,Pdgfb,Lif,Spred1,Flt1,Dusp1 |
| 1.066e-14 | -32.17 | GSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_UP | MSigDB lists | GSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_UP | 187 | 50 | 15632 | 1249 |
Stard7,Tagap,Ap3m2,Cflar,Jak2,Ifit3b,Ccrl2,Oas1a,Ube2e2,Rap1gap2,Ifit3,Casp4,Pilra,Sdc4,Rras2,Fbrsl1,Cdc42ep2,Lrp8,Abcb1a,Ikzf1,Igsf6,Il4i1,Stard5,Slc44a1,Cyfip1,Rhof,Spn,Syk,Rnf114,Slfn3,Rtn1,Oas1g,Dgka,Icosl,Slfn4,Rgl1,Card6,Hck,Crlf3,Nod1,Itga4,Nfkbie,Aebp2,Cebpd,Sat1,Swap70,Klhl25,Tcf4,Birc2,Casp1 |
| 1.066e-14 | -32.17 | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_DN | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_DN | 187 | 50 | 15632 | 1249 |
Gbp2,Hvcn1,Psmb10,Cd74,Marcksl1,Cdyl2,Treml2,Gbp4,Gbp9,Slc15a3,Fut8,Oaf,Psmb9,N4bp1,Casp1,Insl6,Il2rg,Oas1g,Il12rb1,Scn1b,Ube2l6,Irf7,Cd86,Plk2,Lgals9,Csrp1,Ifit1bl2,Samhd1,Ahr,Zbp1,Prdx1,Ccnd2,Il18bp,Irgm2,Fos,Ifit1bl1,Agpat4,Asf1a,Irf1,Stat1,Cd200,Casp7,Hat1,Etv6,Egln3,Oas1a,Isg20,Cnn3,Casp4,Il10 |
| 1.074e-14 | -32.17 | positive regulation of T cell activation | biological process | GO:0050870 | 187 | 46 | 20694 | 1406 |
Spn,Hsph1,Icosl,Tnfsf9,H2-Ab1,Egr3,Cd86,Cd80,Il6,Il2rg,Hlx,Ripk2,Il18,Itgal,Lgals9,Nlrp3,Cd274,Cd83,Pik3r6,Il1b,Nfkbiz,Il4ra,Il12rb1,Tnfrsf14,Cav1,Tnfsf14,Nck1,Ikzf1,Ccl2,Irf1,Tnfsf4,Rasgrp1,H2-Aa,Syk,Stat5a,Ap3b1,Socs1,Bcl6,Malt1,Cd74,Ccdc88b,Il12b,Vcam1,Nfkbid,Il15,Ccl5 |
| 1.086e-14 | -32.15 | GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 200 | 52 | 15632 | 1249 |
Apaf1,Nod1,Rnf34,Pml,Aim2,Prdx5,Mdm2,Rffl,Casp3,Cycs,Ifi209,Birc2,Ifi205,Psmb9,Traf2,Casp1,Src,Tnf,Ifi213,Plaur,Thbs1,Tnfsf10,Serpinb9,Ifi208,Tnfsf15,Ifi207,Ifi214,Mul1,Nlrp3,Cdkn2d,Fas,Ift57,Il6,Myc,Nlrc4,Bcl2l11,Fam162a,Jak2,Mefv,Ifi204,Mmp9,Casp7,Casp2,Egln3,Ifi203,Sirt1,Ifi211,Mndal,Casp8,Tnfsf14,Birc3,S100a8 |
| 1.106e-14 | -32.14 | GSE43863_NAIVE_VS_MEMORY_TH1_CD4_TCELL_D150_LCMV_UP | MSigDB lists | GSE43863_NAIVE_VS_MEMORY_TH1_CD4_TCELL_D150_LCMV_UP | 138 | 42 | 15632 | 1249 |
Ripk2,Ifit3b,Cxcl10,Irf1,Cmpk2,Trafd1,Sp110,Il15ra,Epsti1,Vegfc,Lhx2,Gch1,Hk1,Lcp2,Cd274,Klf2,Ifit3,Psme2,Ube2l6,Isg20,Trim21,Wars,Atf3,Aim2,Rtp4,Isg15,Ddx58,Stat2,Cd74,Ciita,Tap1,Gbp2,Ccl12,Nlrc5,D16Ertd472e,Psmb9,Tnc,Parp14,Cebpd,Stk40,Samd9l,Vcan |
| 1.129e-14 | -32.11 | GO_REGULATION_OF_INFLAMMATORY_RESPONSE | MSigDB lists | GO_REGULATION_OF_INFLAMMATORY_RESPONSE | 261 | 61 | 15632 | 1249 |
Ccl12,Cx3cr1,Spn,Zyx,Ptpn2,Ccl2,Il6,Pla2g4a,Nod2,Abr,Nr1h3,Cx3cl1,Nlrp3,Il15,Nfkb1,Tnfrsf1b,Ednrb,Birc3,Rabgef1,S100a8,Nos2,Casp4,Il10,Pla2g7,Smpdl3b,Rictor,Socs3,C3,Tlr9,Tnfsf4,Mefv,Lyn,Adrb2,Tlr2,Ccl4,Tnip1,Jak2,Casp1,Tnf,Birc2,Bcl6,Psma6,Sele,Calcrl,Myd88,Ccl3,Tnfaip3,Hck,Ccl5,Serpine1,Slc7a2,Osm,Zc3h12a,Tlr3,Cd55,Ptger4,Il18,Il12b,Ptgs2,Adora2b,Il1b |
| 1.142e-14 | -32.10 | BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS | MSigDB lists | BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS | 29 | 19 | 15632 | 1249 |
Oas1a,Xaf1,Tdrd7,Oas2,Plscr1,Ifit3,Irf7,Eif2ak2,S100a8,Agrn,Tap1,Tnfsf10,Fpr2,Isg15,Ifit3b,Ifi35,Oas1g,Stat1,Oasl1 |
| 1.150e-14 | -32.10 | positive regulation of cellular biosynthetic process | biological process | GO:0031328 | 1964 | 221 | 20694 | 1406 |
Ikzf1,Il27,Pim2,Taf4b,Sertad3,Pml,Atf3,Bambi,Syk,Cited2,Stat4,Il1a,Ccl3,Daxx,Tnf,Fzd1,Tcf4,Sod2,Jun,Pcgf5,Junb,Arid5b,Max,Tlr1,Cd74,Pou3f1,Fabp3,Dr1,Phip,Igf1r,Larp1,Psip1,Cd40,Mtdh,Mycl,Icam1,Ccl5,Irs2,Jmjd6,Kat2b,Ifnb1,Fam129a,Plscr1,Spn,Cd38,Hsph1,Rap2c,Adora2b,Casz1,Klf6,Atm,Nfil3,Ahrr,Ptgs2,Fos,Ier2,Bcl9,Sirt1,Arf4,Hhex,Acsl5,Irf8,Lmo4,Ptch1,Htr2b,Helz2,Pbx1,Ahr,Ncoa7,Tnip1,Osm,Klf7,Irf1,Hdac1,Map2k4,Nr4a1,Acvr1,Irf2,Hinfp,Il10,Ets2,Ptger4,Irf4,Dtx3l,Hivep3,Med13,Edn1,Nsd3,Hmga1,Nod2,Csf3,Hivep2,Dyrk2,Icosl,Tnfsf8,Ass1,Ldlr,Rnf14,Nos2,Parp9,Il18,Zc3h12a,Ythdf1,Notch1,Gfi1,Pid1,Tlr2,Pim1,Myd88,Serp1,Met,Acvrl1,Nck1,Zfp281,Arid5a,Pla2g4a,Etv5,Nampt,Egr2,Cacybp,Nlrc5,Mdfic,Cx3cl1,Ppp1r15a,Agrn,Kdm6b,Rgcc,Egr1,Fbxo4,Prdm9,Thbs1,Lhx2,Bmp2,Rel,Acvr1b,Hif1a,Nfkb2,Il6,Jag1,Tnfrsf8,Ciita,Hmga2,Il1b,Fubp1,Tet2,Polr2g,Mapkapk2,Ifnar1,Ikbkg,Tlr3,Nr4a3,Relb,Nfkb1,Pcx,Crlf3,Batf,Spic,Pf4,Tlr9,Adrb2,Nfkbia,Slc9a1,Med21,Mllt6,Maml2,Arid4a,Cenpj,Rbpms,Mecp2,Plagl1,Ell2,Stat5a,Plagl2,Pdgfrb,Cebpd,Dcp1a,Fzd5,Ptpn2,Htr2a,Myc,Nr1h3,Zeb1,Fosb,Etv6,Rhoq,Birc2,Csrnp1,Klf2,Ifrd1,Spen,Il15,Nupr1,Aff1,Stat3,Src,Egr3,Nr3c1,Map2k1,Eif4g2,Hcls1,Stat2,Tfec,Fpr2,Ptafr,Mafg,Lif,Pdgfb,Klrk1,Wdr43,Pou2f2,Plac8,Nlrp3,Stat1,Jak2,Tlr6,Tcea1,Hmgn3,Ddx58,Maff,Inhba,Irf7 |
| 1.228e-14 | -32.03 | regulation of neuron death | biological process | GO:1901214 | 370 | 69 | 20694 | 1406 |
Cx3cr1,Il10,Casp8,Ddit4,Ccl12,Rras2,Map2k4,Abcc1,Fcgr2b,Hdac1,Angpt1,Jun,Sod2,Fzd1,Egln3,Cx3cl1,Tnf,Daxx,Adora2a,Ccl3,Mecp2,Stxbp1,Kdr,Agrn,Kmo,Gclc,Gclm,Nqo1,Csf1,Ccl5,Egr1,Fas,Rel,Casp2,Mt1,Cpeb4,Hsph1,Cd34,Nr3c1,Prnp,Csf3,Stat3,Bcl2l11,Fos,Atm,Il6,Nes,Rilpl1,Hif1a,Axl,Pmaip1,Chmp4b,Il1b,Btg2,Optn,Tnfrsf1b,Il18,Sirt1,Ncoa7,Slc7a11,Cd200,Nr4a3,Clcf1,Hmox1,Cdk5r1,Itpr1,Jak2,Tlr6,Casp3 |
| 1.254e-14 | -32.01 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_DN | 175 | 48 | 15632 | 1249 |
Ifi214,Ifi207,Pfkfb3,Nlrc5,Fam43a,Cept1,Rnf145,Ifi204,Mthfd2,Tnfsf4,Stat1,Pim2,Il13ra1,Frmd6,Znrf1,Mndal,Birc3,Tnfrsf1b,Ifi203,Ifi211,Tifa,Slc39a13,Il1a,Dtx3l,Jmjd6,Socs1,Prdm1,Aim2,Malt1,Etv5,Apaf1,Mvp,Batf,Bmp2,Arid5a,Ifi209,Bcl6,Ifi205,Ifi213,Dusp1,Stat3,Ak4,Serpinb9,Prkx,Plat,Rrs1,Ifi208,Slc7a5 |
| 1.280e-14 | -31.99 | GO_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION | MSigDB lists | GO_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION | 290 | 65 | 15632 | 1249 |
Nr4a3,Il12b,Il18,Map3k8,H2-Ab1,Cd55,Ripk2,Il1b,Vcam1,Cd274,Cd86,Pik3r6,H2-Eb1,Ccl5,Nfkbid,Il12rb1,Icosl,H2-Aa,Cd74,H2-Q7,Malt1,Hlx,Ripk3,Cd83,Ccdc88b,H2-Q6,Traf2,Bcl6,Src,Hsph1,Casp3,Pnp2,Irf1,Adrb2,Lyn,Egr3,Tnfsf4,Ebi3,Il10,Tnfsf14,Cav1,Rictor,Rasgrp1,Zeb1,Ubash3b,Prnp,Il4ra,Nlrp3,Nck1,Tnfrsf14,Il15,Il27,Cd80,Ptpn2,H2-Q4,Spn,Ccl12,Syk,Ap3b1,Nod2,Pde5a,Ifnb1,Irf4,Peli1,Il6 |
| 1.337e-14 | -31.95 | ENK_UV_RESPONSE_EPIDERMIS_DN | MSigDB lists | ENK_UV_RESPONSE_EPIDERMIS_DN | 473 | 89 | 15632 | 1249 |
Acsl1,Filip1l,Ell2,Dck,Rnaset2b,Irf8,Gna15,Dcp1a,Rnf19a,Sirt1,Il4ra,Plagl1,Ccl22,Mapkapk2,Egr1,Abr,Atf3,Pfkfb3,Plau,Hivep2,Ezr,Cxcl14,Nod2,Peli1,Rai14,Spry2,Pim1,Chic2,Ptgs2,Tgfbi,Ptger4,Cd55,Glrx,Abcc4,Plaur,Klf2,Rnaset2a,Nampt,Jarid2,Stx11,Hk2,Slc7a5,Phlda1,Slco3a1,Hif1a,Mxd1,Gbp2,Cd83,Crlf3,Psmb9,Hsph1,Lztfl1,Ccnd1,Dusp8,Pnp2,Egr2,Trib1,Dnajb4,Odc1,Egr3,Gsta3,Dnajb2,Fscn1,Adap2,Isg20,Irs2,Stxbp1,Tle3,Itgav,Ass1,Klf3,Katna1,Dusp2,Map3k8,Rcan1,Phyh,Ppp2r2a,Cxcl1,Fosb,Dusp6,Pde4b,Ext1,Ch25h,Tnfaip3,Pdgfc,Tcf4,Homer1,Txnrd1,Phgdh |
| 1.342e-14 | -31.94 | GSE31622_WT_VS_KLF3_KO_BCELL_DN | MSigDB lists | GSE31622_WT_VS_KLF3_KO_BCELL_DN | 188 | 50 | 15632 | 1249 |
Mcm10,Rnf135,Ube2f,Ccdc88b,Crlf3,Myd88,Mcmbp,Mvp,Plod3,Axl,Ttc39c,Tnfsf8,Nr3c1,Sele,Rnf19b,Shisa3,Grina,Nfkb2,Prkx,Brwd3,Osm,Cd86,Stx11,Lrp8,Tmem176b,Mul1,Pttg1,Zbtb5,Pfkfb3,Tle3,Pik3r5,Slc7a11,Gsdmd,Spn,Klf3,Znfx1,Gpr35,Socs3,Mafg,Rab20,Aida,Itga9,Trib1,Ccl4,Stard7,Nos2,Timeless,Pou2f2,Egln3,Slamf9 |
| 1.342e-14 | -31.94 | GSE17721_LPS_VS_CPG_2H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_2H_BMDC_UP | 188 | 50 | 15632 | 1249 |
Rnd3,Sdc4,Rtp4,Nxf1,Trim13,Ddx60,Ifrd1,Fos,Znfx1,Ass1,Fam43a,Nfil3,Frmd6,Dusp16,Polr2g,Lpar1,Zfp36,Trim21,Ptch1,Gem,Psmb8,Isg15,Calcrl,Cd180,Lif,Magohb,Marcksl1,Ccng2,B3gnt5,Tnfsf8,Lrp4,Cst7,Gypc,Slc25a37,Dusp1,Cmpk2,Cldnd1,Pcdh7,Tapbpl,Gpr85,Rcan1,Fam53c,Larp1,Maff,Inhba,Mmp13,Trim26,Plk2,Gja1,Brd2 |
| 1.407e-14 | -31.89 | GSE29618_BCELL_VS_PDC_UP | MSigDB lists | GSE29618_BCELL_VS_PDC_UP | 163 | 46 | 15632 | 1249 |
Plekha2,Birc3,Cd69,Mmd,Isg20,Fam111a,Ppfibp2,Jun,Bcl2a1b,Nfkbia,Ezr,Ift57,Stap1,Peli1,Myc,Fcgr2b,Pikfyve,Irs2,Il4ra,Egr1,Evl,Klf7,Rras2,Klf2,Tuba4a,Junb,Hk2,Parp12,Snx2,Arid5b,Kcna3,Cd55,Clic4,Bcl2a1a,Tank,Swap70,Plekhf2,Sp140,Dusp1,Bcl2a1d,Hif1a,Rhoh,Ier2,Aim2,Cd83,Traf5 |
| 1.446e-14 | -31.87 | regulation of transcription by RNA polymerase II | biological process | GO:0006357 | 2015 | 225 | 20694 | 1406 |
Mycl,Mtdh,Psip1,Rbl1,Cd40,Tshz1,Phip,Dr1,Ifnb1,Jmjd6,Jdp2,Kat2b,Max,Arid5b,Junb,Pou3f1,Stat4,Cited2,Pcgf5,Jun,Tcf4,Sod2,Fzd1,Plk3,Tnf,Daxx,Ifi204,Ccl3,Il1a,Mxd1,Prdm1,Ikzf1,Atf3,Brwd3,Pml,Taf4b,Sqstm1,Helz2,Lmo4,Ptch1,Cav1,Klf7,Osm,Tnip1,Ncoa7,Ahr,Ifi209,Pbx1,Arf4,Etv3,Klf3,Sirt1,Irf8,Hhex,Nfil3,Atm,Klf6,Bcl9,Ier2,Fos,Ahrr,Ifi213,Hsph1,Timeless,Mier3,Plscr1,Nfxl1,Edn1,Nod2,Hmga1,Irf4,Zfp36,Med13,Atp2b4,Ets2,Hdac1,Irf1,Dach1,Il10,Hinfp,Acvr1,Irf2,Nr4a1,Foxp4,Klf8,Tlr2,Hmox1,Zc3h12a,Il18,Pid1,Gfi1,Notch1,Htra1,Ifi208,Parp9,Gbp4,Csf3,Hivep2,Ifi203,Ccne1,Jarid2,Tnfsf8,Kmt5a,Dnajb4,Eno1,Brd2,Zhx2,Notch2,Egr1,Rgcc,Bcl6,Ifi214,Gdf15,Ppp1r15a,Ednrb,Txn1,Kdm6b,Agrn,Nlrc5,Egr2,Kdr,Cx3cl1,Zfp281,Nck1,Mafk,Acvrl1,Met,Phf6,Ifi207,Nampt,Etv5,Arid5a,Ifi205,Tlr3,Ikbkg,Crlf3,Nfkb1,Relb,Ccnd1,Psmd10,Nr4a3,Rfx5,Mdm2,Btg2,Pttg1,Trib3,Tet2,Fubp1,Il1b,Tal2,Hmga2,Il6,Nfkb2,Acvr1b,Hif1a,Ciita,Sap30,Mamld1,Jag1,Lhx2,Prdm9,Nmral1,Rel,Zbtb5,Bmp2,Spen,Ifrd1,Klf2,Csrnp1,Rhoq,Myc,Ptpn2,Fzd5,Plagl2,Cebpd,Fosb,Zeb1,Etv6,Nr1h3,Mecp2,Arid4a,Aebp2,Stat5a,Ell2,Hopx,Plagl1,Slfn1,Med21,Slc9a1,Adrb2,Nfkbia,Tlr9,Pf4,Spic,Batf,Maml2,Mllt6,Ezr,Tcea1,Jak2,Stat1,Bcor,Irf7,Inhba,Ddx58,Maff,Hmgn3,Ifi211,Sp140,Plac8,Pou2f2,Mndal,Nlrp3,Pdgfb,Lif,Mafg,Ptafr,Batf2,Nr3c1,Egr3,Stat3,Stat2,Tfec,Hcls1,Map2k1 |
| 1.471e-14 | -31.85 | GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_UP | 182 | 49 | 15632 | 1249 |
Htra1,Plscr1,Rhou,Cep350,Plekha2,Tax1bp1,Plekhn1,Kif5c,Mtmr14,Il4i1,Bbx,Abcb1a,Rin2,Psd,Ccl12,Rnf114,Morc3,Tiparp,Psmd10,Pfkfb3,F10,Kif9,Rbms2,Sgcb,Spred1,Nxf1,Arrdc4,Prnp,Kat2b,Wdfy1,Ccl5,Ccr1,Junb,Jarid2,Asns,Rnf19b,Crkl,Tmem229b,Batf2,Sat1,Aebp2,Dusp1,Src,Rgs14,Mvp,Mdfic,Irf2,Nfkbil1,Hif1a |
| 1.471e-14 | -31.85 | GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN | 182 | 49 | 15632 | 1249 |
Il15ra,Il2rg,Tapbpl,Hp,Oas1g,Ube2l6,Stxbp3,Tap2,Rnaset2a,Ripk3,Cd38,Hck,Myd88,Usp18,Psmb10,Agtrap,Psme1,C1ra,Prdx5,Pnp2,Eno1,Tpst1,Cst7,Rnaset2b,Sema4a,Ifi35,Oasl1,Stat1,C3,Oas1a,Xaf1,Rasgrp1,Psme2,Atxn7l1,Marco,Psmb8,Dach1,Hk3,Tap1,Pilra,Tspo,Fpr2,P2ry14,Fcgr2b,Mmp14,Gsdmd,Aoah,Ass1,Sod2 |
| 1.473e-14 | -31.85 | ICSBP_Q6 | MSigDB lists | ICSBP_Q6 | 228 | 56 | 15632 | 1249 |
Ifit3,Mov10,Sik3,Psmb8,Nfkb1,Syne2,Med13,Ifit3b,Ptk2,Casp7,Cpeb4,Ifi35,Gsdmd,Il18bp,Ifnb1,Bbx,Tap1,Il27,Col4a2,Zbp1,Adar,Tor1aip1,Dgka,Parp12,Uba7,Arl5b,Tnfsf15,Phf6,Tapbpl,Atp10a,Ripk2,Dio2,Pkp4,Tfec,Sp110,Thbs1,Itpr1,Psmb9,Zmynd15,P2ry13,Armcx6,Sp140,Prdx5,Tapbp,Fut8,Batf2,Slc15a3,Ifi44,Ly75,Usp18,Socs1,Isg15,Ifih1,Dtx3l,Pigv,Tsku |
| 1.595e-14 | -31.77 | innate immune response-activating signal transduction | biological process | GO:0002758 | 69 | 27 | 20694 | 1406 |
Irak3,Irak2,Cd300lf,Cd14,Mapkapk2,Lgals9,Tlr1,Ifih1,Tlr3,Tlr6,Nod2,Tnip1,Prkce,Tnip3,Tlr2,Clec4e,Ddx58,Tlr9,Nfkbia,Myd88,Cd86,Trim12c,Klrk1,Irgm2,Ripk2,Tifa,Tnf |
| 1.688e-14 | -31.71 | KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY | 52 | 25 | 15632 | 1249 |
Nfkbib,Ikbkg,Ccl5,Nfkb1,Card6,Birc3,Casp8,Cxcl1,Il1b,Ripk2,Il18,Mefv,Il6,Ccl2,Nod2,Ccl12,Casp1,Nfkbia,Tnf,Birc2,Nlrc4,Nod1,Tnfaip3,Nlrp3,Tab2 |
| 1.697e-14 | -31.71 | positive regulation of transport | biological process | GO:0051050 | 1075 | 141 | 20694 | 1406 |
Hcls1,Ptprj,Sec24a,Hap1,Fpr2,Kcnj2,Casp1,Clec5a,Src,Casp4,Cox17,Gpr68,Nr3c1,Ripk2,Tnfsf15,Cxcl10,Ptafr,Scn1b,Pdgfb,Lif,Nlrp3,Akt3,Sele,Zc3h12a,Tomm70a,Clec4n,Cd300lf,Clec4e,Ddx58,Tlr2,Frmd4a,Jak2,Sphk1,Uaca,Glrx,Tnfsf4,Scyl2,S100a8,Ezr,Mllt6,Il10,Rab21,Ccl2,Fcgr1,Slc9a1,Adrb2,Nfkbia,Aim2,Adora2a,Tspo,Cxcl1,Ehd1,Mmp13,Abcb1a,Mecp2,Ptger4,Vegfc,Kmo,Nr1h3,Ptk2,Fzd5,Pdgfrb,Hcar2,Il15,Serpine1,Nod2,Edn1,Stap1,Homer1,Rhoq,Hspa2,Ifih1,Adora2b,Prnp,Rab9,Cd38,Cacnb3,Cd34,Ptgs2,Il2rg,Abr,Hif1a,Il6,Il1b,Cd274,Il15ra,Lgals9,Pmaip1,Acsl5,Axl,Sirt1,Mdm2,Sdc1,Prkce,Cdk5r1,Clcf1,Nr4a3,Cav1,Tnfrsf14,Osm,Il4ra,Gja1,Htr2b,Ptch1,Itpr1,Ifnar1,Ccl12,Arid5a,Pla2g4a,Rasgrp1,Fcgr2b,Sdc4,Ccr1,Met,Serp1,Angpt1,Tnf,Plk3,Cx3cl1,Ccl3,Il1a,P2ry2,P2ry12,Cacna1d,Stxbp1,Ccl4,Syk,Tlr1,Fabp3,C3,Gsdmd,Ednrb,Cd14,Lipg,Ccl5,Hk1,Rgcc,Irs2,Dync1h1,Nlgn2,Fgr |
| 1.772e-14 | -31.66 | lymphocyte activation | biological process | GO:0046649 | 425 | 75 | 20694 | 1406 |
Axl,Rhoh,Hhex,Pou2f2,Plcl2,Itgal,Ifna1,Swap70,Il18,Fgl2,Tnfaip3,Relb,Gpr18,Clec4e,Ahr,Clec4d,Ripk3,Clcf1,Itgav,Gja1,Ifnar1,Sema4a,Cd86,Ptprj,Dock10,Tnfsf8,Stx11,Pik3cd,Spn,H2-Ab1,Icosl,Stat3,Ripk2,Bcl2a1d,Ifna4,Ebi3,Il6,Atm,Klrk1,Raet1e,Ifna5,Cd74,Cd180,Il12b,Bcl6,Gadd45g,Malt1,Irf4,Ptpn2,Fzd5,Treml2,Psmb10,Notch2,Ifnb1,Jmjd6,Egr1,Il15,Fas,Icam1,Cd40,H60b,Tnfsf4,Nck1,Slamf8,Ifna6,Prdx1,Ikzf1,Irf1,Batf,Stat5a,Rsad2,Azi2,Ptger4,Syk,Ifna2 |
| 1.772e-14 | -31.66 | positive regulation of catabolic process | biological process | GO:0009896 | 425 | 75 | 20694 | 1406 |
Map2k1,Ctsc,Ldlr,Bcl2l11,Hspa1b,Plk2,Ankib1,Rnf14,Irgm2,Sesn3,Mul1,Ripk2,Hif1a,Il6,Atm,Ppp2r3a,Il1b,Polr2g,Acsl5,Zc3hav1,Trib3,Trim13,Rnf139,Sirt1,Zc3h12a,Ier3,Tnfrsf1b,Arel1,Tiparp,Btg2,Optn,Mdm2,Hmox1,Prkce,Tlr2,Psmd10,Trim30a,Trib1,Tnfaip3,Ikbkg,Gja1,Hk2,Pim2,Ezr,Irgm1,Tlr9,Adrb2,Rnf19a,Pnpt1,Tnf,Plk3,Hspa1a,Plekhn1,Kdr,Mov10,Sh3bp4,Gclc,Mefv,Ptk2,Rnf19b,Cop1,Zfp36,Htr2a,Myc,Dtx3l,Bnip3,Nupr1,Nod2,Dnajb2,Irs2,Nod1,Tmem67,Trim21,Larp1,Mtdh |
| 1.786e-14 | -31.66 | cell chemotaxis | biological process | GO:0060326 | 204 | 48 | 20694 | 1406 |
Trem1,Egr3,Xcr1,Flt1,Cxcl10,Pdgfb,Cxcl9,Lox,Saa3,Lpar1,Itga9,Ccl22,Il1b,Crkl,Cxcl11,Cxcl3,Sbds,Ccl2,Gpr35,Pf4,Slamf8,Abcc1,Ccl12,Nr4a1,Ccr1,Cx3cr1,S100a8,Ccl4,Syk,Ccl7,Ccl3,Cx3cl1,Cxcl1,Ednrb,Pdgfrb,Ccl8,Pde4b,Ccr3,Ccl9,Ch25h,Il1rn,Vcam1,Ccrl2,Cxcl14,Csf3r,Dock4,Cxcl2,Ccl5 |
| 1.841e-14 | -31.63 | KIM_LRRC3B_TARGETS | MSigDB lists | KIM_LRRC3B_TARGETS | 48 | 24 | 15632 | 1249 |
H2-Q7,Cd74,Isg15,Ifi214,Ifi207,Tap1,Ifi213,Ifit1bl1,H2-Q4,H2-Q6,Ifi205,Ifi209,Ifi44,Tapbp,H2-Ab1,Ifi204,Ifit1bl2,Ccl5,Mndal,Ifi211,Psme2,Ifi208,Oas2,Ifi203 |
| 1.853e-14 | -31.62 | cell migration | biological process | GO:0016477 | 837 | 118 | 20694 | 1406 |
Carmil1,Lrp8,Dock4,Socs7,Csf3r,Ccrl2,Sema4c,Ptk2,Mmp14,Itgb8,Rhoc,Prag1,Prkx,Ch25h,Rac3,Ccl9,Ccr3,Ccl8,Itga4,Pdgfrb,Tspo,Cxcl1,Pdpn,Ccl7,Mcoln2,Phactr4,Cx3cr1,S100a8,Nr4a1,Ddit4,Acvr1,Sdc2,Slamf8,Pf4,Ccl2,Plau,Sbds,Tnfaip3,Cxcl3,Crkl,Flrt3,Sele,Notch1,Itga9,Lpar1,Gpc1,Cxcl9,Pdgfb,Cxcl10,Flt1,Vcan,Pvr,Xcr1,Sema3c,Egr3,Src,Ccl5,Cxcl2,Icam1,Fut8,Nox1,Cxcl14,Vcam1,Mark2,Il12b,Il1rn,Pde4b,Fscn1,Arid5b,Ednrb,Kitl,P2ry12,Cx3cl1,Tnf,Ccl3,Syk,Ccl4,Bambi,Kdr,Pml,Ccr1,Spata13,Katna1,Ccl12,Abcc1,Sdc4,Nck1,Pstpip2,Acvrl1,Gpr35,Met,Sell,Cxcl11,Sdc1,Cdk5r1,Plat,Itgav,Htr2b,Gja1,Rhof,Asap3,Axl,Il1b,Arf4,Ccl22,Palld,Syne2,Saa3,Lox,Hif1a,Sema4a,Nrp2,Thbs1,Pik3cd,Rapgef2,Cd34,Spn,Trem1 |
| 1.856e-14 | -31.62 | GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_DN | MSigDB lists | GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_DN | 183 | 49 | 15632 | 1249 |
P2ry14,Cdc42ep2,Fcgr1,Tap1,Igsf6,Irf4,Ctsc,Ifi35,Irf1,Acvr1b,Tnfaip2,Jak2,Cdkn1a,Vrk2,Prkar2b,S100a8,Psmb8,Sik3,Casp4,Alas1,Psme2,St3gal5,Ier2,Sell,Socs1,Psmb10,Stat2,Hck,Gbp2,Cd38,Rgs3,Stat5a,Psmb9,Fchsd2,Tapbp,Fgl2,H2-Ab1,Cd55,Cxcl10,Il2rg,Prkx,Trafd1,Ccl5,Plek,Tap2,H2-Aa,Ext1,Ube2l6,Wars |
| 1.856e-14 | -31.62 | GSE36009_WT_VS_NLRP10_KO_DC_DN | MSigDB lists | GSE36009_WT_VS_NLRP10_KO_DC_DN | 183 | 49 | 15632 | 1249 |
Rffl,Irgq,Stk40,Ift57,Cpd,Bcl2a1d,Acvr1,Ifnar1,Bcl2a1b,Pik3r5,Gramd1a,Slc2a1,Tank,Swap70,Klhl25,Extl2,Relb,Mark2,Spred1,Klf7,Mcoln2,Nupr1,Etv3,Fam133b,Cyth3,Pdlim7,Plscr1,Sap30,Srxn1,Hivep3,Jdp2,Tnfrsf1b,Nfkb1,Birc3,Tnfaip2,Fam20c,Nfkb2,Hcls1,Bcl2a1a,Acsl5,Pcdh7,Abcc1,Rcl1,Filip1l,St3gal1,Mtmr14,Rab20,Mafg,Adora2b |
| 1.880e-14 | -31.60 | GO_POSITIVE_REGULATION_OF_MAPK_CASCADE | MSigDB lists | GO_POSITIVE_REGULATION_OF_MAPK_CASCADE | 428 | 83 | 15632 | 1249 |
Il1a,Icam1,Tab2,Cd74,Trim12c,Lif,Daxx,Pdgfc,Ccl3,Mdfic,Nod1,Bmp2,Traf2,Cd40,Src,Tnf,Glipr2,Dbnl,Adora2b,Map3k8,Fpr1,Crkl,Tlr3,Ripk2,Zc3h12a,Dusp5,Il1b,Htr2b,Thbs1,Gcnt2,Kitl,Irak2,Fzd5,Osm,Pdgfrb,Map2k1,Pik3r6,Ccr1,Dusp6,Ccl5,Rapgef2,Pdgfb,Ccl22,Cx3cl1,Mul1,Fas,Tlr6,Mapkapk2,Tnfrsf14,Angpt1,Htr2a,Jun,Eif2ak2,Map3k6,Gadd45b,Flt1,Ccl12,Syk,Pik3r5,Nod2,S1pr2,Mid1,Pde5a,Gadd45g,Edn1,Spry2,Prkce,Il6,Ccl2,Lpar1,Adrb2,Nox1,Sema4c,Tlr9,C3,Jak2,Ccl4,Kdr,Tnfrsf1b,Ikbkg,Rasgrp1,Ksr1,Cysltr2 |
| 1.946e-14 | -31.57 | regulation of peptide transport | biological process | GO:0090087 | 767 | 111 | 20694 | 1406 |
Cd34,Cacnb3,Cd38,Prnp,Il6,Hif1a,Ptgs2,Mdm2,Sirt1,Lgals9,Cd274,Hmga2,Pim3,Il1b,Ifnar1,Htr2b,Gja1,Il4ra,Slc7a11,Osm,Klf7,Lyn,Tnfrsf14,Clcf1,Cdk5r1,Prkce,Serp1,Angpt1,Pml,Arid5a,Rasgrp1,Pde3b,Syk,Rsad2,Cacna1d,Mdfic,Il1a,Ccl3,Cx3cl1,Plk3,Tnf,Mapkbp1,Cd14,Gsdmd,Cd74,Tlr1,Txn1,Cd40,Pfkl,Fgr,Nlgn2,Irs2,Slc16a1,Rgcc,Hk1,Ccl5,Srgn,Rabgef1,Gpr68,Casp4,Map4k4,Src,Clec5a,Casp1,Hap1,Sec24a,Hcls1,Lif,Arg2,Traf2,Tnfsf15,Ripk2,Rhbdf2,Gbp4,Nos2,Tomm70a,Clec4n,Zc3h12a,Tnfrsf1b,Nlrp3,Uaca,Tlr6,Jak2,Tnfaip3,Frmd4a,Hmgn3,Tlr2,Ddx58,Cd200,Clec4e,Tlr9,Hdac1,Ccl2,Il10,Ezr,S100a8,Tnfsf4,Glrx,Ptger4,Vegfc,Mmp13,Rab11fip1,Adora2a,Aim2,Socs1,Fzd5,Nr1h3,Ifih1,Dnaja1,Nod2,Hcar2 |
| 1.957e-14 | -31.56 | GO_CYTOKINE_RECEPTOR_BINDING | MSigDB lists | GO_CYTOKINE_RECEPTOR_BINDING | 250 | 59 | 15632 | 1249 |
Tnfsf8,Casp3,Stat3,Tnf,Traf2,Bmp2,Myd88,Ifna2,Ccl3,Lif,Traf1,Il1a,Tnfsf15,Ifna6,Tyk2,Cxcl2,Csf3,Il12rb1,Inhba,Ccl5,Gdf15,Osm,Kitl,Bambi,Tnfsf10,Il1rn,Cxcl1,Pf4,Il1b,Vegfc,Il12b,Cxcl10,Il6,Ccl2,Stap1,Cxcl14,Ifna5,Ifnb1,Ccl12,Ifna1,Il27,Il15,Spred1,Cx3cl1,Ccl22,Csf1,Ccrl2,Casp8,Tnfsf14,Il10,Ccl4,Jak2,Clcf1,Cflar,Itga5,Stat1,Tlr9,Ebi3,Tnfsf4 |
| 1.969e-14 | -31.56 | GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | 264 | 61 | 15632 | 1249 |
Wdr59,Ifi208,Fzd1,Ccl5,Gja1,Ppp1r15a,Asns,Il1b,Tlr3,Ptger4,Hmox1,Zc3h12a,Adora2b,Ptgs2,Pim1,Tnc,Slc39a4,Mdm2,Axl,Ifi213,Casp1,Ifi209,Cd40,Slc2a1,Ifi205,Myd88,Tnfrsf8,Upp1,Hif1a,Icam1,Sphk1,Slc9a1,Ifi211,Sirt1,Ifi203,Casp2,Nfkb1,Ccne1,Tnfsf14,Cav1,Mndal,Casp8,Cdkn1a,Cpeb4,Max,Ifi204,Irf1,Map2k4,Lyn,Bnip3,Kcnj2,Gsdmd,Cnn2,Eif2ak2,Fos,Jun,Il15,Ifi207,Fas,Atf3,Ifi214 |
| 2.001e-14 | -31.54 | GO_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 1683 | 220 | 15632 | 1249 |
Cebpd,Psma6,Egr2,Hspa1a,Cd40,Hsph1,Src,Mdfic,Relb,Notch1,Tnfrsf8,Crlf3,Traf1,Trim12c,Sertad3,Ddx58,Hif1a,Il1a,Calcrl,Lif,Malt1,Irf2,Adora2a,Csf3,Pdgfb,Klf2,Nampt,Arid4a,Pf4,Thbs1,Bambi,Nsmaf,Cxcl10,Ptafr,Zc3h12a,Ptger4,Nod2,Edn1,Irf4,Fos,Agrn,Nlrc5,Htr2a,Ciita,Nlrp3,Plagl1,Egr1,Atf3,Ifi203,Met,Hivep3,Sirt1,Jag1,Ptch1,Irf8,Ccne1,Tnip1,Cflar,Adrb2,Dyrk2,Stat1,Nox1,Prdx5,Ythdf1,Mecp2,Tnfsf8,Stat3,Tcf4,Ifi209,Plagl2,Irak3,Cd38,Pdgfc,Pbx1,Batf,Sav1,Fabp3,Zfp281,Tab2,Csrnp1,Aim2,Pdgfrb,Irf7,Osm,Med21,Serpine1,Fzd5,Htr2b,Il1b,Kitl,Nr4a3,Adora2b,Ripk2,Pcgf5,Hmox1,Pla2g4a,Ptpn2,Cited2,Hmga1,Spic,Nlrc4,Psip1,Rbl1,Ahr,Klf7,Cd80,Il27,Nr1h3,Kat2b,Pou2f2,Ifi211,Zeb1,Trim14,Nos2,Lmo4,Rel,Pid1,Rnf14,Lhx2,Ifi204,Pim2,Ptgir,Mtdh,Tlr9,Acvrl1,Acvr1,Rhoq,Nr3c1,Ifi205,Ifnar1,Ifi213,Ripk3,Bmp2,Nod1,Sphk1,Icam1,Hhex,Maff,Tlr1,Ifi208,Cd86,Junb,Il12b,Ptgs2,Kdm6b,Larp1,Myc,Il6,Ikzf1,Jun,Tet2,Ccl12,Nfkbia,Hinfp,Phip,Trim13,Tlr6,Lrp8,Mapkapk2,Plscr1,Bcl9,Il10,Rnf31,Igf1r,Asf1a,Kdr,Hcls1,Tlr2,Mafg,Irf1,Acvr1b,Ebi3,Mafk,Hdac1,Serp1,Traf2,Tnf,Klf6,Ncoa7,Etv5,Traf5,Fzd1,Inhba,Trim26,Fosb,Ppp1r15a,Ccl5,Irak2,Nfkb2,Arid5b,Tlr3,Ifnb1,Ets2,Syk,Ass1,Sqstm1,Eif2ak2,Nr4a1,Plac8,Spn,Ifi207,Il15,Irs2,Ifi214,Nck1,Etv6,Nfkbib,Med13,Slc9a1,Trim21,Mndal,Ahrr,Ikbkg,Nfkb1,Atm,S100a8,Ldlr,Arf4,Polr2g,Jak2 |
| 2.029e-14 | -31.53 | regulation of lymphocyte mediated immunity | biological process | GO:0002706 | 190 | 46 | 20694 | 1406 |
Fcgr1,H60b,H2-Q6,Tnfsf4,Fcgr2b,Arid5a,Rasgrp1,Rsad2,Stat5a,Tnf,Bcl6,Fzd5,Malt1,C3,Cd55,Parp3,Nectin2,Clec2d,Il12b,Cd40,Nod2,Ifnb1,H2-Q7,Tap2,Serpinb9,Spn,H2-M2,Pvr,Il18rap,Raet1e,Klrk1,Il6,Traf2,H2-T24,Il18,Tnfrsf1b,Lgals9,Tap1,Nlrp3,Il1b,Pik3r6,H2-T10,H2-T22,Clcf1,Ripk3,H2-Q4 |
| 2.032e-14 | -31.53 | GO_POSITIVE_REGULATION_OF_LOCOMOTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_LOCOMOTION | 382 | 77 | 15632 | 1249 |
Tnfsf14,Sema3c,P2ry2,Pla2g7,Met,Syne2,Trim21,Csf1,Lpar1,Acvr1b,Lyn,Pik3cd,Sema4a,Sema4c,Ptk2,Mmp9,Itga5,Igf1r,Jak2,Kdr,Ccl4,Dock4,Jun,Flt1,Itgav,Ccl12,Cxcl14,Edn1,Il6,Mmp14,Prkce,Cx3cl1,Irs2,Col18a1,Tnfrsf14,Angpt1,Rras2,Plau,F10,Cd274,Serpine1,Pdgfrb,Ccr1,Ccl5,Myadm,Rapgef2,Cxcl2,Nrp2,Pdgfb,Ptgs2,Ptafr,Cxcl10,Ptger4,Zc3h12a,Vegfc,Pf4,Il1b,Cmklr1,Cxcl1,Gcnt2,Kitl,Thbs1,Swap70,Tnf,Src,Stat5a,Acvr1,Glipr2,Cd74,Icam1,Hif1a,Sphk1,Fgr,Itga4,Pdgfc,Notch1,Bmp2 |
| 2.102e-14 | -31.49 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | 223 | 55 | 15632 | 1249 |
Slc7a11,Bcl2l11,Sqstm1,Fos,Jun,Zyx,Gclm,Ifrd1,Dusp4,Nqo1,Gadd45g,Atf3,Fas,Palld,Il15,Atp2b4,Me1,Ubr4,Gem,Zfp36,Stx6,Casp7,Filip1l,Ell2,Dnajb4,Cdkn1a,Dnajb2,Dusp1,P4ha2,Hsph1,Klf6,Dync1h1,Slc16a3,Hspa1a,Sat1,Rab21,Mdm2,Gsr,Mxd1,Upp1,Jmjd6,Slco3a1,Gdf15,Tuba4a,Ppp1r15a,Plk2,Serpine1,Slc7a5,Wars,Maff,Smox,Hmox1,Plat,Kitl,Stip1 |
| 2.116e-14 | -31.49 | GSE17721_CTRL_VS_LPS_24H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_24H_BMDC_DN | 190 | 50 | 15632 | 1249 |
Pim1,Grina,Tgfbi,Smc5,Htr2b,Mitd1,Slfn9,Cacybp,Plk2,Ccl5,Tshz1,Stxbp3,Rab10,Itga4,Traf5,Slc2a1,Gypc,P4ha2,Stat5a,Psma6,Hdac1,Ier3,Odc1,Mtmr14,Etnk1,Cdkn1a,Dusp16,Lhx2,Kdr,Clcf1,Gbp7,Irf8,Sema3c,Hk1,Psmb8,Tdrd7,Hat1,Atxn7l1,St3gal5,Pdss1,Cnn3,Gbe1,Nr1h3,Etv3,Slc28a2,Hinfp,Map3k6,Cpd,Cox17,Slfn8 |
| 2.312e-14 | -31.40 | GO_POSITIVE_REGULATION_OF_CELL_DEATH | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_DEATH | 559 | 99 | 15632 | 1249 |
Abr,Atf3,Trim13,Nlrp3,Bcl2l11,Jun,Il6,Myc,Nqo1,Casp7,Nox1,Adrb2,Il10,Cysltr2,Sirt1,Eef1e1,Casp2,Pml,Hif1a,Nod1,Tnfrsf8,Bmp2,Ripk3,Daxx,Notch1,Src,Dusp1,Casp1,Cd40,Casp3,Bcl2a1d,Ldha,Zc3h12a,Ptgs2,Nsmaf,Il12b,Bcl2a1a,Thbs1,Tnfsf10,Plaur,Hcar2,Phlda1,Tnfsf15,Nfkbid,Fas,Nck1,Col18a1,Mul1,Cdk5r1,Tspo,Gadd45b,Eif2ak2,Sqstm1,Bcl2a1b,Nlrc4,Dnaja1,Ptpn2,Bnip3,Ctsc,Pla2g4a,Gadd45g,Ifnb1,Ift57,Mmp9,Lpar1,Lyn,Jak2,Ppp2r1b,Fam162a,Cdkn1a,S100a8,Atm,Dcun1d3,Cav1,Casp8,Slc9a1,Egln3,Nupr1,Sav1,Apaf1,Plagl2,Tnf,Ifit2,Traf2,Arhgef3,Bcl6,Cycs,Hp,Tlr3,Ripk2,Nr4a3,Il1b,Ccl5,Dusp6,Ppp1r15a,Osm,Ddit4,Inhba,Rapgef2 |
| 2.339e-14 | -31.39 | GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 184 | 49 | 15632 | 1249 |
Tnfrsf8,Cd83,Sphk1,B3gnt5,Mafk,Nfkbie,N4bp1,Tnf,Serp1,Eno1,Snapc1,Ptges,Zhx2,Stip1,Lacc1,Plaur,Dusp5,Ldha,Mcm6,Map3k8,Slc43a3,Stx11,Maff,Nfkbid,G3bp2,Rapgef2,Map4k4,Pde4b,Sipa1l1,Tpi1,Mapkapk2,Il4ra,Etv3,Cyth3,Dusp2,Aftph,Sod2,Pik3r5,Nfkbia,Hivep2,Hmga1,Tiparp,Rgs1,Arf4,Cdkn1a,Dusp16,Ell2,Mafg,Gna15 |
| 2.339e-14 | -31.39 | GSE3039_B2_VS_B1_BCELL_UP | MSigDB lists | GSE3039_B2_VS_B1_BCELL_UP | 184 | 49 | 15632 | 1249 |
Spire1,Slamf8,Acp2,Pilrb1,Sipa1l1,Junb,Ifit1bl2,Phlpp2,Ube2l6,Hck,Crim1,Pdgfc,Bmp2,Cd40,Slc25a37,Ccnd1,Arhgap26,Itga9,Ap3m2,Rims3,Marco,Atm,Tmem176a,Ccrl2,Zfp36,Slpi,Tifa,Isg20,Nr1h3,Plagl1,Cyth3,Tmem176b,Tnfrsf14,Enpp4,Slamf7,Ciita,Pilrb2,Fbrsl1,Dock4,Tspan3,B4galt4,Agrn,Nr4a1,Ifit1bl1,Cx3cr1,Phlpp1,Stard5,Bbx,Irgm2 |
| 2.473e-14 | -31.33 | GO_REGULATION_OF_INTERLEUKIN_1_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_1_PRODUCTION | 57 | 26 | 15632 | 1249 |
Tnfaip3,Ifi207,Nod1,Jak2,Ifi214,Nlrp3,Mefv,Sphk1,Ifi204,Pml,Zc3h12a,Aim2,Ptger4,Ifi203,Nod2,Errfi1,Ifi208,Ifi211,Ifi209,Mndal,Ifi205,Il10,Ifnar1,Casp1,Gsdmd,Ifi213 |
| 2.649e-14 | -31.26 | GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN | 191 | 50 | 15632 | 1249 |
Arf4,Tnip1,Ldlr,Esd,Cdkn1a,Ptk2,Ptgir,Ell2,Gpd2,Nfkbib,Stat4,Tnfrsf1b,Mov10,Zc3h12c,Hdc,Cd80,Tspo,Tor1aip2,Irgm2,Ifrd1,Cnot4,Hivep2,Gadd45b,Nfkbia,Bcl2l11,Itgav,Znfx1,Tiparp,Nfkb2,Cmpk2,Larp1,Ptger4,Rnf19b,Fndc3a,Serpinb9,Nr4a3,Ext1,Cxcl2,Adora2a,Cd83,Myd88,Ifit1,Usp18,Isg15,Traf1,Aebp2,Mafk,Ehd1,Traf2,Arhgef3 |
| 2.766e-14 | -31.22 | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | 793 | 126 | 15632 | 1249 |
Nfkb1,Sema3c,Sik3,Casp8,Cep350,Plod2,Zeb1,Spen,Med13,Usp12,Tdrd7,Syne2,Ptk2,Lpar1,Lyn,Map2k4,Rbms1,Ust,Ldlr,Chd9,Wdr43,Abcc1,Ptpn2,Cnot4,Ap3b1,Rin2,Ifrd1,Phlpp1,Dusp4,Mid1,Nck1,Pikfyve,Klf7,Aff1,Atp11b,Cdyl,Gja1,Flrt2,Map2k1,Serpine1,Ext1,Stxbp3,Phlpp2,Slc25a12,Snx2,Rapgef2,Ppp2r3a,Adora2b,Arid5b,Sec24a,Pkp4,Ppp2r2a,Klf6,Txnrd1,Homer1,Ankrd17,Tpst1,Rab21,Rbpms,Mecp2,Tlk2,Cers6,Tab2,Flnb,St3gal5,Plscr1,Hat1,Kpna3,Filip1l,Kif5c,Ell2,Ier3,Igf1r,Hivep2,Cenpe,Tiparp,Jun,Dock4,Ppp2r5a,Myc,Bbx,4932438A13Rik,Phip,Gbe1,Dmxl2,Rras2,Atp2b4,Arid4a,Slc4a7,Jarid2,Nampt,Rgl1,Myo1b,Daam1,Fubp1,Ascc3,Sipa1l1,Dusp5,Smc5,Fndc3a,Nsmaf,Dek,Rsbn1,Serpinb2,Plaur,Vegfc,Zhx2,Sec24b,Dusp1,N4bp1,Itpr1,Swap70,Tank,Nr3c1,Mdn1,Fut8,Fchsd2,Acvr1,Ccnd1,Kdm5b,Ube2e1,Malt1,Hif1a,Crim1,Myo10,Mdfic |
| 2.945e-14 | -31.16 | HALLMARK_MTORC1_SIGNALING | MSigDB lists | HALLMARK_MTORC1_SIGNALING | 198 | 51 | 15632 | 1249 |
Sqstm1,Slc7a11,Ctsc,Ifrd1,Tpi1,Gbe1,Gclc,Prdx1,Me1,P4ha1,Psat1,Plod2,Nfkbib,Eef1e1,Egln3,Ppa1,Hmgcs1,Mthfd2,Idi1,Ldlr,Nfil3,Cdkn1a,Pfkl,Txnrd1,Serp1,Eno1,Slc2a1,Pnp2,Phgdh,Gsr,Fgl2,Nupr1,Sla,Tuba4a,Nampt,Atp6v1d,Asns,Ppp1r15a,Cacybp,Slc7a5,Btg2,Ddit4,Hk2,Wars,Ldha,Ak4,Trib3,Pgk1,Tcea1,Glrx,Stip1 |
| 3.185e-14 | -31.08 | DELYS_THYROID_CANCER_UP | MSigDB lists | DELYS_THYROID_CANCER_UP | 424 | 82 | 15632 | 1249 |
Mvp,Gbp2,Rgs3,Etv5,Upp1,Atp11a,Icam1,Lif,Prdm1,Plk3,Bcl2a1d,Ccnd1,Pnp2,Tnc,Rbbp8,Timp1,Mtus1,Lrp4,Armcx6,P4ha2,Igf2bp2,Thbs1,Pcdh7,Il1rn,Cxcl1,Bcl2a1a,Hmox1,Dusp5,Hp,Cd55,Wars,Inhba,Slc7a5,Tnfsf15,Scn1b,Nrp2,Gdf15,Map4k4,Dusp6,Ccr1,Tspo,Sdc4,Plau,Sdc1,Ccnd2,Fas,Abr,Pcx,Dusp4,Cpd,Pde5a,Vcan,Ccl2,Igsf6,Ctsc,Ggct,Tiparp,Msr1,Bcl2a1b,Agrn,Cx3cr1,Map3k6,Cdkn1a,Trem1,Lyn,Ier3,Tlr2,Odc1,Ms4a6d,Itga9,Stat1,C3,Il13ra1,Endod1,Met,St3gal5,Slpi,Med13,Trim14,Bcl9,Lcn2,Marco |
| 3.232e-14 | -31.06 | GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP | MSigDB lists | GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP | 179 | 48 | 15632 | 1249 |
Il1rn,Cxcl1,Bcl2a1a,Il1b,Plaur,Igf2bp2,Ripk2,Kdm6b,Clec5a,Phlda1,Pdlim7,Cxcl2,AA467197,Nampt,Osm,Tnfaip3,Malt1,Mxd1,Traf1,Sell,Fgr,Upp1,Bcl2a1d,Arhgap26,Glipr2,Ehd1,Slc25a37,Acpp,Nfil3,Trem1,Mthfd2,Sema4a,Tnip3,Ccrl2,Birc3,Marco,Clec4e,Slamf7,Pfkfb3,Olr1,Nlrp3,Sgms2,Tmtc2,Dusp2,Nod2,Dhrs9,Bcl2a1b,Plac8 |
| 3.232e-14 | -31.06 | GSE11057_PBMC_VS_MEM_CD4_TCELL_UP | MSigDB lists | GSE11057_PBMC_VS_MEM_CD4_TCELL_UP | 179 | 48 | 15632 | 1249 |
Tmem176b,Fpr2,Sgms2,Lpcat2,Gng11,Clec4e,Spred1,Hk3,Rab32,Aoah,Tet2,Pla2g4a,Igsf6,Il13ra1,Tnfaip2,Cd300lf,Trem1,Prkar2b,Hdc,Pla2g7,Mxd1,Cd180,Tnfrsf8,Pdgfc,Hvcn1,Swap70,P2ry12,P2ry13,Tcf4,Csf3r,Slc15a3,B3gnt5,Rtn1,Hmox1,Il18,Ptafr,Il1rn,Cmklr1,Serpinb2,Fmnl2,Tfec,Pf4,Ccr1,Slc31a2,Dusp6,Cd86,Slc2a6,Bst1 |
| 3.232e-14 | -31.06 | GSE12366_GC_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_GC_VS_NAIVE_BCELL_DN | 179 | 48 | 15632 | 1249 |
Mob3b,Fndc3a,Cd55,Herc6,Klf2,Pde4b,Hk2,Dgka,Ifi208,Dtx3l,Sell,Hhex,Parp10,H2-Q7,Cd83,Ifi209,Ifi205,Psmb9,H2-Q6,Casp1,Plod3,Ifit2,Dusp1,Ifi213,Dock10,Cish,Ifi204,Stat1,Il13ra1,Dyrk2,Max,Pmepa1,Ust,Notch2,Rbms1,Mndal,Ifi203,Cd69,Ifi211,Ifi214,Ddx60,Ifi207,Zbp1,Rhof,H2-Q4,Parp9,Mllt6,Abcb1a |
| 3.690e-14 | -30.93 | GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_DN | MSigDB lists | GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_DN | 186 | 49 | 15632 | 1249 |
Ifit1,Nupr1,Isg15,Traf1,Egr2,Psma6,Rsad2,Bcl2a1d,Plod3,Tank,Acpp,Slfn3,Bcl2a1a,Gng12,Serpinb9,Ccl5,Dusp6,Gch1,Slc4a7,Junb,Hsd17b12,Rrs1,Irf7,Slfn4,Pnpt1,Il15,Stxbp1,Nxf1,Il6,Myc,Slc44a1,Prkce,Ctsc,Ifnb1,Itgav,Bcl2a1b,Nfkbia,Gadd45b,Ldlr,Idi1,Ccl4,Cd82,Ell2,Gpd2,Rcn1,Pou2f2,Lap3,Gem,Il10 |
| 3.827e-14 | -30.89 | negative regulation of viral life cycle | biological process | GO:1903901 | 82 | 29 | 20694 | 1406 |
Slpi,Oas1a,Apobec3,Oasl2,Rsad2,Shfl,Eif2ak2,Fam111a,Tnf,Oasl1,Trim26,Oas3,Plscr1,Pml,Trim56,Isg20,Parp10,Resf1,Trim21,Ifnb1,Oas1g,Ccl5,Adar,Ifitm1,Zc3h12a,Zc3hav1,Trim13,Isg15,Oas1b |
| 3.992e-14 | -30.85 | defense response to protozoan | biological process | GO:0042832 | 34 | 19 | 20694 | 1406 |
Irf8,Il10,Ccdc88b,Il12b,Gbp3,Pf4,Gbp2,Batf,Irf4,Irgm2,Il4ra,Batf2,Cd40,Il6,Gbp8,Gbp9,Iigp1,Gbp2b,Gbp7 |
| 4.074e-14 | -30.83 | GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN | 180 | 48 | 15632 | 1249 |
Rnf139,Ier2,Hhex,Traf1,Usp18,Sla,Cd14,Traf5,Ifnar1,Dusp1,Tnf,Kdm6b,Cxcl10,Map3k8,Tmem229b,Pim1,Brd2,Gdf15,Junb,Pde4b,Igsf8,Osm,Ppp1r15a,Phlda1,Phlpp2,Ext1,Btg2,Cxcl2,Egr1,Nfkbiz,Slamf7,Nfkbia,Cyfip1,Fos,Dusp2,Gadd45g,Parp9,Psd,Socs3,Ier3,Rgs1,Ccl4,Gfpt1,Dusp16,Zfp36,Bcl9,Dcp1a,Ccrl2 |
| 4.074e-14 | -30.83 | GO_MYELOID_CELL_DIFFERENTIATION | MSigDB lists | GO_MYELOID_CELL_DIFFERENTIATION | 180 | 48 | 15632 | 1249 |
Adar,Ifi207,Ifi214,Ikzf1,Irf4,Ptpn2,Jun,Tet2,Hcls1,Fam20c,Jak2,Gfi1,Mmp9,Tmod3,Pik3cd,Lyn,Ifi204,Csf1,Ifi211,Ifi203,Sirt1,Mndal,Casp8,Irf8,Batf,Relb,Pml,Hhex,Jmjd6,Pde1b,Batf2,Casp3,Src,Tnf,Ifi213,Bcl6,Ifi209,Ifi205,Prkx,Clec5a,Ifi208,Csf3,Inhba,Snx10,Arid4a,Junb,Cd86,Klf2 |
| 4.311e-14 | -30.78 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | biological process | GO:0002460 | 158 | 41 | 20694 | 1406 |
Relb,Nod2,Il4ra,Irf7,Icam1,Fas,Dennd1b,Serpinb9,C1rl,Gadd45g,Pou2f2,Bcl6,Fgl2,Il18,Irf4,Swap70,Cd55,Cd74,C3,C1ra,Il12b,Serpinb9b,Nfkb2,Raet1e,Il6,Il18bp,Jag1,Spn,Treml4,Fcgr1,Icosl,Myd88,Batf,Stat3,H2-Ab1,Sema4a,H60b,Fcgr2b,Stx11,Il18rap,Ctsc |
| 4.345e-14 | -30.77 | regulation of protein transport | biological process | GO:0051223 | 726 | 106 | 20694 | 1406 |
Traf2,Arg2,Nos2,Rhbdf2,Gbp4,Ripk2,Tnfsf15,Clec5a,Src,Map4k4,Casp4,Gpr68,Hcls1,Sec24a,Hap1,Casp1,Jak2,Tlr6,Uaca,Cd200,Clec4e,Ddx58,Tlr2,Frmd4a,Hmgn3,Tnfaip3,Tnfrsf1b,Zc3h12a,Clec4n,Tomm70a,Nlrp3,Mmp13,Vegfc,Ptger4,Socs1,Aim2,Adora2a,Rab11fip1,Ccl2,Hdac1,Tlr9,Glrx,Tnfsf4,Ezr,Il10,Dnaja1,Ifih1,Hcar2,Nod2,Fzd5,Nr1h3,Hif1a,Il6,Ptgs2,Prnp,Cd38,Cacnb3,Cd34,Htr2b,Gja1,Ifnar1,Prkce,Cdk5r1,Lyn,Tnfrsf14,Klf7,Osm,Il4ra,Slc7a11,Sirt1,Mdm2,Il1b,Pim3,Cd274,Lgals9,Syk,Pde3b,Plk3,Tnf,Mapkbp1,Cx3cl1,Ccl3,Il1a,Mdfic,Cacna1d,Rsad2,Serp1,Angpt1,Rasgrp1,Arid5a,Pml,Nlgn2,Fgr,Cd40,Pfkl,Rabgef1,Ccl5,Srgn,Hk1,Rgcc,Slc16a1,Irs2,Gsdmd,Cd14,Txn1,Tlr1 |
| 4.670e-14 | -30.69 | regulation of defense response to virus | biological process | GO:0050688 | 77 | 28 | 20694 | 1406 |
Ccl5,Ddx58,Il15,Il12rb1,Stat1,Elmod2,Ankrd17,Cgas,Dhx58,Il1b,Traf3ip2,Il12b,Zc3hav1,Ddx60,Ifna1,Zc3h12a,Fgl2,Dtx3l,Aim2,Gbp4,Parp9,Mul1,Apobec3,Htra1,Pml,Treml4,Spn,Il27 |
| 4.862e-14 | -30.65 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 269 | 61 | 15632 | 1249 |
Il15,Zc3hav1,Ddx60,Trim13,Cx3cl1,Bnip3,Pla2g4a,Il6,Ccl2,Nod2,Cxcl14,Scarf1,Sqstm1,Ccl12,Jak2,Kdr,Ccl4,Tnip1,Tlr9,Tnfsf4,C3,Lpar1,Adrb2,Tlr2,Csf1,Pla2g7,Sirt1,Met,S100a8,Tnfsf14,Nod1,Ccl3,Cd74,Cd180,Hif1a,Dhx58,Tnf,Swap70,Ankrd17,Cmklr1,Cxcl1,Thbs1,Vegfc,Pf4,Il1b,Tlr3,Larp1,Ptger4,Ripk2,Adora2b,Ptgs2,Il18,Cxcl10,Il12b,Pdgfb,Cxcl2,Ccr1,Ccl5,Serpine1,Osm,Pdgfrb |
| 4.982e-14 | -30.63 | Type II interferon signaling (IFNG) | WikiPathways | WP1253 | 33 | 22 | 4813 | 540 |
Stat1,Stat2,Ifit2,Ifnb1,Cxcl9,Icam1,Il1b,Eif2ak2,Tap1,Jak2,Nos2,Irf8,Irf4,Isg15,Irf2,Socs1,Ciita,Psmb9,Irf1,Cxcl10,Gbp2b,Socs3 |
| 4.983e-14 | -30.63 | TBK1.DF_UP | MSigDB lists | TBK1.DF_UP | 255 | 59 | 15632 | 1249 |
Slco3a1,Il1a,Tnfaip3,Rgs3,Lipg,Cd83,Tpst1,Swap70,Plekhf2,Dpy19l1,Hspa2,Nfkbie,Acvr1,Pnp2,Slc39a4,Rab21,Minpp1,Grina,Chic2,Zc3h12a,Dusp5,Hmox1,Plaur,Gca,Cxcl1,Daam1,Gch1,Snx10,Tbc1d13,Ppp2r3a,Slc30a1,Ciapin1,Atf3,Abr,Dusp14,Atp11b,Gng11,Plau,Extl2,Tmem184b,Itgav,Trim36,Ift57,Vcan,Rin2,Peli1,Pik3cd,Mmp9,Endod1,Casp7,Nfil3,Igf1r,Tnfaip2,Chd9,Pid1,Nfkb1,S100a8,Rabgef1,Eno2 |
| 5.124e-14 | -30.60 | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN | 181 | 48 | 15632 | 1249 |
Timp1,P2ry13,Bcl6,Oas3,Cst7,Casp1,Fgl2,Cebpd,Sat1,Fgr,Apaf1,Irak3,Hck,Cd86,Tuba4a,Csrp1,Fzd1,Hk2,Sap30,Il18,Ptger4,Ldha,Rtn1,Il1b,Il1rn,Acsl5,Cnn2,Aoah,Rab32,Vcan,Igsf6,Nlrp3,Evl,Egr1,Tpi1,Ahr,Ciita,Pilra,Pid1,Kctd12,Pstpip2,Tlr2,Sema4a,Mthfd2,Ppa1,Itga5,Tmem123,Tnfaip2 |
| 5.186e-14 | -30.59 | regulation of secretion | biological process | GO:0051046 | 911 | 124 | 20694 | 1406 |
Nod2,Hcar2,Ifih1,Edn1,Kmo,Kdm5b,Nr1h3,Htr2a,Fzd5,Rab11fip1,Aim2,Socs1,Adora2a,Vegfc,Ptger4,Mmp13,S100a8,Rab21,Il10,Ezr,Tnfsf4,Glrx,Hdac1,Slc30a1,Tlr9,Adrb2,Inhba,Tnfaip3,Ddx58,Clec4e,Cd200,Hmgn3,Frmd4a,Tlr2,Hmox1,Sphk1,Tlr6,Jak2,Notch1,Nlrp3,Clec4n,Zc3h12a,Tnfrsf1b,Apba1,Ripk2,Tnfsf15,Rhbdf2,Nos2,Lif,Traf2,Arg2,Ptafr,Hap1,Casp1,Sec24a,Gpr68,Casp4,Map4k4,Nr3c1,Clec5a,Src,Slc16a1,Irs2,Ccl5,Srgn,Rab10,Rabgef1,Rgcc,Hk1,Fgr,Nlgn2,Pfkl,Cd40,Stxbp3,Cd74,Il1rn,Tlr1,Oas2,Ednrb,Gsdmd,Cd14,Cacna1d,P2ry12,Rsad2,Cx3cl1,Tnf,Mapkbp1,P2ry2,Il1a,Ccl3,Syk,Pde3b,Stxbp1,Pml,Rasgrp1,Arid5a,Sdc4,Serp1,Angpt1,Klf7,Lyn,Tnfrsf14,Il4ra,Osm,Sdc1,Clcf1,Prkce,Htr2b,Gja1,Rims3,Ifnar1,Lgals9,Il1b,Hmga2,Pim3,Cd274,Sirt1,Abr,Il6,Hif1a,Adora2b,Cd38,Cd34,Rab9 |
| 5.224e-14 | -30.58 | regulation of establishment of protein localization | biological process | GO:0070201 | 758 | 109 | 20694 | 1406 |
Dnaja1,Ifih1,Nod2,Hcar2,Fzd5,Nr1h3,Ptger4,Vegfc,Cenpj,Mmp13,Rab11fip1,Adora2a,Aim2,Socs1,Tlr9,Hdac1,Ccl2,Il10,Ezr,Tnfsf4,Glrx,Uaca,Jak2,Tlr6,Tnfaip3,Hmgn3,Frmd4a,Tlr2,Ddx58,Cd200,Clec4e,Clec4n,Tomm70a,Zc3h12a,Tnfrsf1b,Nlrp3,Arg2,Traf2,Tnfsf15,Ripk2,Gbp4,Rhbdf2,Nos2,Gpr68,Map4k4,Casp4,Src,Clec5a,Casp1,Hap1,Sec24a,Hcls1,Cd40,Pfkl,Fgr,Nlgn2,Irs2,Slc16a1,Rgcc,Hk1,Ccl5,Srgn,Rabgef1,Cd14,Gsdmd,Tlr1,Txn1,Pde3b,Syk,Rsad2,Cacna1d,Mdfic,Ccl3,Il1a,Cx3cl1,Plk3,Tnf,Mapkbp1,Serp1,Angpt1,Pml,Rasgrp1,Arid5a,Ifnar1,Gja1,Htr2b,Slc7a11,Il4ra,Osm,Klf7,Tnfrsf14,Lyn,Cdk5r1,Prkce,Mdm2,Sirt1,Pmaip1,Lgals9,Cd274,Pim3,Il1b,Il6,Hif1a,Ptgs2,Cd34,Cacnb3,Cd38,Hsph1,Prnp |
| 5.348e-14 | -30.56 | GO_REGULATION_OF_CYTOKINE_SECRETION | MSigDB lists | GO_REGULATION_OF_CYTOKINE_SECRETION | 126 | 39 | 15632 | 1249 |
Tlr2,Lyn,Clec5a,Zc3h12a,Ptger4,Tlr9,Tnfsf4,Htr2b,Il1b,Cd274,Il10,Rabgef1,H2-Eb1,Clec4n,Rasgrp1,Tlr1,Fgr,Socs1,Cx3cl1,Nlrp3,Il4ra,Il1a,Pml,Tlr6,Aim2,Angpt1,Tnfrsf14,Cd14,Clec4e,Cd34,Ifnar1,Casp1,Syk,Src,Gsdmd,Ezr,Tnf,Nod2,Il6 |
| 5.720e-14 | -30.49 | VANTVEER_BREAST_CANCER_ESR1_DN | MSigDB lists | VANTVEER_BREAST_CANCER_ESR1_DN | 228 | 55 | 15632 | 1249 |
Tnf,Apobec3,Eno1,Birc2,Gpsm2,Tbc1d1,Phgdh,Nfkbie,Bcl2a1d,Hif1a,Cd180,Ncoa7,Myo10,Tnfaip3,Ccl5,Lad1,Asns,Nmi,Slc2a6,Wars,Rcan1,Chic2,Slamf8,Slc43a3,Pim1,Mcm6,Bcl2a1a,Il15ra,Snn,Ass1,Sod2,Bcl2a1b,Rnf114,D16Ertd472e,Ctsc,Dusp2,Katna1,Optn,Ifrd1,Mid1,Nck1,Cx3cl1,Hk3,Psat1,Plekhg1,Marco,Lmo4,Fabp7,Plscr1,Rnf145,Odc1,Lyn,Fscn1,Rbms1,Tmem123 |
| 6.107e-14 | -30.43 | GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP | 169 | 46 | 15632 | 1249 |
Sp110,Tnfsf10,Irf7,Sipa1l1,Klf2,Dusp6,Gch1,Junb,Jarid2,4930523C07Rik,Ext1,Sell,Psmb10,Ier2,Itga4,Irak3,Tnfrsf8,Crlf3,Csf3r,Rgs14,Casp1,Dusp1,Klf6,Ccng2,Cebpd,Arhgap26,Sema4a,Lyn,Pik3cd,Notch2,Sik3,Tnfrsf1b,Rap1gap2,Zfp36,Spen,Nxf1,Nlrp3,Cdkn2d,Il15,Gadd45b,Crbn,Cx3cr1,Plac8,Nod2,4932438A13Rik,Peli1 |
| 6.107e-14 | -30.43 | GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_DN | MSigDB lists | GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_DN | 169 | 46 | 15632 | 1249 |
Chst11,Cd200r4,Gadd45b,Phf11a,Phf11c,Pttg1,Plscr1,Cysltr2,Smpdl3b,Jdp2,Psmb8,Itgal,Rgs1,Gbp2b,Ell2,Phf11d,Carhsp1,Pnp2,Casp3,Dhx58,Rsad2,Gsr,Arhgap26,Cst7,Insl6,Phf11b,Rbbp8,Swap70,Sla,Prpf38a,Cd38,Prdm1,Ifih1,Usp18,Myadm,Snx10,Acsl5,Trafd1,Il15ra,Dusp5,Ptprj,Ptger4,Cxcl10,Nsmaf,Nr4a3,Mcm6 |
| 6.185e-14 | -30.41 | pattern recognition receptor signaling pathway | biological process | GO:0002221 | 67 | 26 | 20694 | 1406 |
Tnip3,Prkce,Tlr2,Clec4e,Ddx58,Nod2,Tnip1,Tlr6,Ifih1,Tlr3,Tlr1,Mapkapk2,Lgals9,Cd14,Irak3,Cd300lf,Irak2,Tnf,Irgm2,Ripk2,Tifa,Cd86,Trim12c,Myd88,Nfkbia,Tlr9 |
| 6.236e-14 | -30.41 | GO_RESPONSE_TO_ABIOTIC_STIMULUS | MSigDB lists | GO_RESPONSE_TO_ABIOTIC_STIMULUS | 965 | 144 | 15632 | 1249 |
Cnn2,Plac8,Eif2ak2,Psip1,Dnaja1,Cited2,Bnip3,Pla2g4a,Mmp14,Fas,Cdkn2d,Col18a1,Ifi214,Cx3cl1,Tspo,Ifi207,Atm,Nfkb1,Dcun1d3,Cav1,Nos2,Plod2,Mndal,Casp8,Slc9a1,Ifi211,Egln3,Hmgcs1,Cpeb4,Lpar1,Ifi204,Dnajb4,Rcsd1,Map2k4,Lyn,Clcn7,Fam162a,Cdkn1a,Tnf,Ifi209,Tnc,Tlk2,Errfi1,Mecp2,Gpr68,Hspa2,Plk3,F11r,Kmo,Rnf34,Myd88,Cd14,Hvcn1,Apaf1,Cd38,Gja1,Ccl5,Asns,Ppp1r15a,Fosb,Pdgfrb,Osm,Ddit4,Icosl,Vasn,Mmp13,Tlr3,Hmox1,Vcam1,Lrp11,Plat,Snn,Il1b,Htr2b,Flt1,Nfkbia,Ccl12,Fos,Jun,Kcnj2,Edn1,Il6,Myc,Prkce,Sdc2,Egr1,Trim13,Plau,Gclc,Htr2a,Atp2b4,Pdk3,Tnfsf14,Ptch1,Timeless,Sirt1,Ifi203,Casp2,Nox1,Socs3,Irf1,Adrb2,Src,Ifi213,Dusp1,N4bp1,Casp1,Psmb9,Rgs14,Itpr1,Cd40,Birc2,Ifi205,Slc2a1,Hspa1a,Casp3,Pde1b,Mdm2,Ccnd1,Pml,Mthfr,Hif1a,Icam1,Il1a,Agtrap,Tnfrsf8,Bmp2,Notch1,Daxx,Relb,Txn1,Junb,Btg2,Pdgfb,Ifi208,Ptger4,Dnaja2,Ldha,Ptgs2,Ptafr,Il12b,Cxcl10,Thbs1,Tfec |
| 6.433e-14 | -30.37 | GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_DN | 182 | 48 | 15632 | 1249 |
S100a8,Tnfrsf1b,Itgal,Ifit3,Tnfsf14,Hdc,Lcn2,Isg20,Il18rap,Ifit3b,Jak2,Igf1r,Nfil3,Gadd45b,Ifit1bl1,Trmt1l,Bcl2l11,Ets2,Katna1,Nek6,Tlr6,Ifit1bl2,Gch1,Cd274,G3bp2,AA467197,Pde7b,Stx11,Herc6,Clec4d,Cdc42ep4,Ikbke,Irak2,Glrx,Hcar2,Ppp2r2a,Tnf,Plekhf2,N4bp1,Mtus1,Slc15a3,Trim12c,Pigv,Rnf135,Isg15,Slco3a1,Sla,Ifit1 |
| 6.579e-14 | -30.35 | negative regulation of viral genome replication | biological process | GO:0045071 | 57 | 24 | 20694 | 1406 |
Eif2ak2,Tnf,Oasl1,Fam111a,Rsad2,Oasl2,Shfl,Apobec3,Oas1a,Slpi,Parp10,Isg20,Plscr1,Oas3,Adar,Ccl5,Ifnb1,Oas1g,Resf1,Isg15,Oas1b,Zc3hav1,Zc3h12a,Ifitm1 |
| 7.210e-14 | -30.26 | GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_UP | MSigDB lists | GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_UP | 189 | 49 | 15632 | 1249 |
Il15ra,Bcl2a1a,Nfkb2,Ptgs2,Rtn1,Wars,Gpr132,Btg2,Nmi,Plk2,Gnb4,Gys1,Pbx1,F11r,Usp18,Mxd1,Psme1,Pml,Ccnd1,Errfi1,Bcl2a1d,Psma6,Birc2,Tpst1,Parp8,Tnf,Plekha5,Cdkn1a,Xcr1,Adam19,Kdr,Cacnb3,Mthfd2,Sema4a,Gpd2,Trip13,Timeless,Nfkbib,Irf8,Casp4,Olr1,Gclc,Ciapin1,Nek6,Irf4,Tor1aip2,Il4i1,Znfx1,Bcl2a1b |
| 7.210e-14 | -30.26 | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN | 189 | 49 | 15632 | 1249 |
Pttg1,Ifi214,Fas,Ifi207,Atp2b4,Ahr,Prdx1,Zbp1,Ezr,Nod2,Optn,Chst11,Ifi204,Endod1,Actb,Tnip1,Cd82,Adam19,Mndal,Tor3a,Tnfrsf1b,Ifi203,Rap1gap2,Etv6,Syne2,Ifi211,Tifa,Cd74,Rnf135,Rnf139,Mcoln2,Ncoa7,Ttc39c,Timp1,Ifi209,Tank,Ifi205,Klf6,Ifi213,Acvr1,Rab11fip1,Rnf19b,Ldha,Dusp5,Osbpl3,Cldnd1,Snx10,Ifi208,Piezo1 |
| 7.210e-14 | -30.26 | GSE18893_TCONV_VS_TREG_24H_CULTURE_DN | MSigDB lists | GSE18893_TCONV_VS_TREG_24H_CULTURE_DN | 189 | 49 | 15632 | 1249 |
Casp7,Egr3,Stat1,Oasl1,Ifit3b,Cflar,Trem1,Psat1,Ifit3,Bcl9,Tifa,Trip13,Timeless,Hivep3,Sdc4,Lpcat2,Cenpe,Rapgef5,Tspan3,Ets2,Pla2g4a,Il4i1,Slc43a3,Inpp1,Cmpk2,Dusp6,Asah2,Dmwd,Irf7,Tlr1,Tmem26,Nfkbid,Slc30a4,Zfp513,Kmo,Ifih1,Pbx1,Ifit1,Etv5,Relb,Ifit2,Bcl6,Rbbp8,Ifi44,Slc15a3,Hdac1,Dhx58,Cers6,Ccng2 |
| 7.392e-14 | -30.24 | BROCKE_APOPTOSIS_REVERSED_BY_IL6 | MSigDB lists | BROCKE_APOPTOSIS_REVERSED_BY_IL6 | 133 | 40 | 15632 | 1249 |
Maff,Eef1e1,Pou2f2,Oas1a,Nmi,Zfp36,Plscr1,Nampt,Junb,Tnfsf10,Ldlr,Map3k8,Pim1,Irf1,Pim2,Dusp5,Stat1,Oas1g,Socs3,Ell2,Dnaja2,Irf4,Stat3,Tmem184b,Jun,Bcl6,Acpp,Ccl12,Bcl2l11,Gadd45b,Hck,Atp2b4,Sla,Socs1,St3gal6,Cd180,Icam1,Mapkapk2,Prdm1,Ier2 |
| 7.427e-14 | -30.23 | GO_POSITIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | 145 | 42 | 15632 | 1249 |
Jak2,Tnfsf10,Fam162a,Casp7,Ifi204,Mefv,Ifi211,Tnfsf15,Ifi208,Psme2,Sirt1,Egln3,Casp2,Ifi203,S100a8,Cav1,Casp8,Mndal,Nod1,Apaf1,Ifi207,Psme1,Aim2,Fas,Pml,Mul1,Ifi214,Nlrp3,Stat3,Casp3,Cycs,Mmp14,Myc,Ift57,Ifi213,Tnf,Casp1,Bcl2l11,Traf2,Nlrc4,Ifi205,Ifi209 |
| 7.492e-14 | -30.22 | regulation of proteolysis | biological process | GO:0030162 | 732 | 106 | 20694 | 1406 |
Serpinb9b,Nlrp3,Tnfrsf1b,Zc3h12a,Rnf139,Trib1,Cycs,Jak2,Prdx5,Stat1,Timp1,Spint2,Nlrc4,Uaca,Tlk2,Casp1,Src,Bcl2l11,Stat3,Casp4,Serpina3f,Rnf14,Serpinb6b,Ripk2,Mul1,Tnfsf15,Usp25,Nr1h3,Cop1,Rnf19b,Mmp14,Ptk2,Ctla2a,Myc,Nupr1,Fas,Gsap,Serpine1,Dnajb2,Serpinb2,Trim21,Birc2,Antxr1,Plaur,Sco1,Nr4a1,S100a8,Psmb8,Birc3,Il10,Hdac1,Psmb9,Apaf1,Serpina3g,Aim2,Adora2a,Rnf34,Hspa1a,Il1b,Trib3,Pmaip1,Psme1,Sirt1,Mmp9,Mdm2,Tnfsf14,Psmd10,Lyn,Cav1,Tnip1,Plat,Ctsc,Hspa1b,Tank,Plk2,Thbs1,N4bp1,Ptgs2,Ankib1,Cflar,Bcl2a1d,Psme2,Il6,Slpi,Mefv,Gclc,Cst7,C3,Malt1,Mmp25,Serpinb9,Nod1,Cdkn2d,Tmem67,Caml,Casp8,Pml,Tnfsf10,Ift57,Rnf19a,Plk3,Tnf,Rffl,Fam162a,Inpp5b,Syk |
| 7.806e-14 | -30.18 | negative regulation of protein phosphorylation | biological process | GO:0001933 | 419 | 73 | 20694 | 1406 |
Hhex,Il1b,Trib3,Rgs14,Pid1,Il18,Sirt1,Zc3h12a,Psmd10,Adar,Myadm,Tnip1,Trib1,Lyn,Tnfaip3,Cav1,Errfi1,Casp3,Crkl,Dusp2,Ptprj,Dusp5,Fam129a,Prnp,Hsph1,Fam72a,Mvp,Gbp4,Dusp8,Dusp1,Spred1,Lif,Il6,Gadd45b,Spred3,Actb,Ppp1r15a,Samsn1,Ptpn2,Aida,Gadd45g,Dusp4,Irak3,Pmepa1,Rabgef1,Kat2b,Cdkn2d,Uchl1,Spry2,Dusp16,Wars,Igf1r,Prkar2b,Dnaja1,Ppp1r15b,Ddit4,Ezr,Parp14,Cdkn1a,Atf3,Irf1,Angpt1,Met,Phlpp1,Nck1,Slfn1,Adora2a,Socs1,Jun,Socs3,Dusp6,Ubash3b,Plpp3 |
| 8.060e-14 | -30.15 | GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 183 | 48 | 15632 | 1249 |
Ifnb1,Dhx58,Errfi1,Il6,Bcl6,Axl,Ezr,Tnf,Nlrc5,Tnfaip3,Relb,Irak3,Angpt1,Tspo,Cd34,Cd83,Ifih1,Nlrp3,Rnf135,Isg15,Mul1,Cx3cl1,Ddx58,Prnp,Pml,Nfkbil1,Uba7,Inhba,Nmi,Ube2l6,Cd274,Il10,Rel,Klf2,Nfkb1,Rabgef1,H2-Eb1,Thbs1,Tax1bp1,Ikbke,Cmklr1,Il12b,Mefv,Zc3h12a,Hmox1,Ptger4,Tnfsf4,Tlr9 |
| 8.060e-14 | -30.15 | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDC_DN | 183 | 48 | 15632 | 1249 |
Cox17,Dtnb,Cpd,Fcgr2b,Peli1,Rai14,Gramd1a,Sod2,Ppp1r14b,Ahr,Slc28a2,Col4a2,Ccnd2,Palld,Pou2f2,Tdrd7,Egln3,Srxn1,Slpi,Lmo4,Dach1,Cacna1d,Ell2,Hdac1,Mecp2,Gsr,Ttc39c,Slc2a1,Notch1,Mdfic,Gbp2,Traf5,Arg2,Socs1,Reps1,Icosl,Asns,Plk2,Serpine1,Pde4b,Rgl1,Brwd3,Pkp4,Gca,Clec5a,Map3k8,Clec4d,Hmox1 |
| 8.579e-14 | -30.09 | cytokine production | biological process | GO:0001816 | 161 | 41 | 20694 | 1406 |
Aim2,Ptgs2,Nos2,Mcoln2,Azi2,Hif1a,Ptafr,Casp1,Trim56,Rel,Tnfsf4,Il18rap,Rasgrp1,Tlr9,Spn,Trem1,Batf,Myd88,Nod2,Nod1,Irf7,Notch2,Lyn,Rgcc,Tlr2,Dennd1b,Ifnar1,Nlrc4,Itgav,Tlr6,Lcp2,Rnf19b,Isg15,Notch1,Nlrp3,Il12b,Il1b,Gadd45g,Optn,Il18,Sirt1 |
| 8.980e-14 | -30.04 | GSE17721_LPS_VS_POLYIC_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_4H_BMDC_UP | 190 | 49 | 15632 | 1249 |
1110038F14Rik,Ccdc86,Ly75,Hspa1a,Ctu1,Calcrl,Isg15,Vasp,Sap30,Igsf9,Snx10,Tshz1,Acsl5,Pcdh7,Nfkb2,Fndc3a,Tra2a,Ncoa5,Parp9,Slc44a1,Ets2,Aoah,Gadd45b,Crbn,Ahr,Pilra,Hinfp,Sgcb,Col4a2,Ccl22,Plagl1,Pikfyve,Ube2e2,Akt3,Itgal,Lcn2,Rabgef1,Jdp2,Igf1r,Pmepa1,Sh3bgrl2,Fam20c,Asf1a,Kdr,Lpar1,Azi2,Acsl1,Endod1,Cd200 |
| 9.005e-14 | -30.04 | GO_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY | 122 | 38 | 15632 | 1249 |
Rnf31,Nfkb1,Ikbkg,S100a8,Nfkbib,Trim14,Tlr2,Ripk2,Tlr9,Mtdh,Tlr3,Il1b,Irak2,Nfkb2,Cflar,Hspa1a,Cd40,Nlrc4,Traf2,Nfkbia,Eif2ak2,Tnf,Psma6,Nod2,Il6,Traf1,Trim12c,Sphk1,Nlrp3,Icam1,Trim13,Tab2,Malt1,Aim2,Irak3,Ripk3,Traf5,Nod1 |
| 9.035e-14 | -30.04 | negative regulation of phosphate metabolic process | biological process | GO:0045936 | 568 | 89 | 20694 | 1406 |
Il1b,Hhex,Trib3,Ier3,Sirt1,Myadm,Ahr,Psmd10,Lyn,Cav1,Ppp2r5a,Tnip1,Casp3,Marf1,Dusp2,Prnp,Dusp5,Plek,Fam129a,Fam72a,Hsph1,Dusp8,Dusp1,Il6,Gadd45b,Spred3,Ppp1r15a,Actb,Samsn1,Dusp4,Aida,Rabgef1,Pmepa1,Uchl1,Cdkn2d,Irs2,Kat2b,Wars,Igf1r,Cdkn1a,Atf3,Met,Angpt1,Nck1,Tnf,Jun,Dusp6,Ubash3b,Rhoh,Rgs14,Pid1,Swap70,Zc3h12a,Il18,Adar,Trib1,Tnfaip3,Errfi1,Crkl,Ptprj,Stat3,Gbp4,Mvp,Pdgfb,Spred1,Lif,Ptpn2,Irak3,Gadd45g,Nupr1,Spry2,Stap1,Dusp16,Dnaja1,Prkar2b,Ddit4,Ppp1r15b,Birc3,Parp14,Ezr,Ppp1r14b,Irf1,Phlpp1,Socs1,Adora2a,Slfn1,Socs3,Plpp3,Phactr4 |
| 9.035e-14 | -30.04 | negative regulation of phosphorus metabolic process | biological process | GO:0010563 | 568 | 89 | 20694 | 1406 |
Dusp5,Fam129a,Plek,Prnp,Hsph1,Fam72a,Dusp2,Marf1,Dusp1,Il6,Dusp8,Sirt1,Ier3,Hhex,Il1b,Trib3,Casp3,Psmd10,Myadm,Ahr,Tnip1,Lyn,Cav1,Ppp2r5a,Met,Angpt1,Nck1,Cdkn1a,Atf3,Dusp6,Ubash3b,Tnf,Jun,Actb,Ppp1r15a,Samsn1,Dusp4,Aida,Spred3,Gadd45b,Wars,Igf1r,Rabgef1,Pmepa1,Cdkn2d,Irs2,Kat2b,Uchl1,Stat3,Ptprj,Pdgfb,Spred1,Lif,Mvp,Gbp4,Il18,Zc3h12a,Swap70,Rhoh,Rgs14,Pid1,Errfi1,Crkl,Adar,Trib1,Tnfaip3,Ppp1r14b,Irf1,Phlpp1,Ddit4,Ppp1r15b,Ezr,Parp14,Birc3,Socs3,Phactr4,Plpp3,Adora2a,Slfn1,Socs1,Ptpn2,Gadd45g,Irak3,Dusp16,Stap1,Dnaja1,Prkar2b,Nupr1,Spry2 |
| 9.241e-14 | -30.01 | multicellular organism development | biological process | GO:0007275 | 4896 | 450 | 20694 | 1406 |
Ehd1,Rnf114,Adora2a,Mov10,Ptger4,Mmp13,Ets2,S100a8,Nr4a1,Acvr1,Plaur,Hinfp,Tnfsf4,Hdac1,Ust,Adgrg6,Adam19,Plau,Serpine1,Adap2,Flrt2,Lrp8,H2-Q7,Tent2,D16Ertd472e,Tsku,Stap1,Homer1,Morc3,Itgb8,Clic5,Hivep3,Gadd45g,Zfp36,Ifna4,Tab2,Nos2,Scn1b,Spred1,Htra1,Ptprj,Tlk2,Tnfsf8,Map4k4,Csf3,Icosl,Clec4e,Tlr2,Clec4d,Hmox1,Tdrd7,Flnb,Gsta3,Rhoh,Notch1,Tiparp,Cd300lf,Sod2,Fzd1,Zswim4,Ifi204,Ccl3,Syk,Pde3b,Pml,Ciapin1,Ccr1,Eya4,Prdm1,Col4a2,Ifnb1,Ccl5,Fgr,Ankrd17,Fndc3a,Igf1r,Wars,Nox1,Tshz1,C3,Cd74,Sec24b,Malt1,Actb,Junb,Mturn,Fos,Abr,Bcl2a1d,Atm,Nes,Adgrl2,Timeless,Cd38,Atp11a,Chst11,Lyn,Slc7a11,Kremen1,Ahr,Clcf1,Lmo4,Htr2b,Ptch1,Txnrd1,Hp,Irf8,Axl,Gpsm2,Pik3r6,Hhex,Arf4,Fam20c,Hopx,Mecp2,Phactr4,Vegfc,Tulp3,Znrf3,Bbx,Ddit4,Sdc2,Slc9a1,Apaf1,Spic,Spry2,Klf2,Ntng2,Csrnp1,Triobp,Birc2,Ppp4r2,Dync1i2,Zeb1,Myc,Plagl2,Lpar1,Batf2,Dst,Pdgfb,Mafg,Lst1,Hcls1,4932438A13Rik,Sema3c,H2-Ab1,Egr3,Plekha5,Stat3,Src,Maff,Adar,Ripk3,Crkl,Stat1,Bcor,Flrt3,Spint2,Pou2f2,Swap70,Mthfd1l,Apba1,Kitl,Cx3cl1,Col11a2,Egr2,Kdr,Setdb2,Arid5a,Fcgr2b,Shisa3,H3f3b,Zfp281,Ift57,Mafk,Serp1,Met,Zhx2,Notch2,Calcrl,Rab10,Egr1,Ext1,Cxcl14,Eno1,Vcam1,Rcan1,Mark2,Rnd1,Kdm6b,Cgas,Spred3,Gadd45b,Plod3,Bcl6,Fabp7,Slc4a7,Pdlim7,Vasp,Sap30,Cflar,Jag1,Il6,Kdm4a,Itga5,Hif1a,Sema4a,Samhd1,Thbs1,Plk2,Cd34,Relb,Ccnd1,Nr4a3,Itgav,Gja1,Dnaaf3,Cemip2,Casp3,Fubp1,Mapkapk2,Tal2,Ppp2r3a,Hmga2,Mdm2,Pdgfc,Clmp,Palld,Tspo,Plpp3,Cenpe,Lnpk,Kif3c,Dach1,Cx3cr1,Rab21,Il10,Cnp,Intu,Map2k4,Irf1,Papss2,Fas,Socs7,Edn1,Sema4c,Mmp14,Sav1,Casp7,Ccr3,Itga4,Irf4,Lrp4,Mul1,Hlx,Stk40,Gpd2,Tmod3,Serpinb6b,Mthfr,Ifna5,Micall2,Hap1,Jarid2,Ldlr,Rrs1,B3gnt5,Clec5a,Hsd17b7,Sbds,Gpr18,Foxp4,Trip10,Prokr1,Gfi1,Scarf1,Sgcb,Zc3h12a,Il18,Tcf4,Jun,Rsad2,Tnf,Il1a,Cited2,Stxbp1,Atf3,Ccl12,Angpt1,Ikzf1,Uchl1,Kat2b,Jmjd6,Irs2,Icam1,Mycl,Nlgn2,Psd,Pou3f1,Tnfaip2,Rpgrip1l,Col27a1,Arid5b,Aida,Insl6,Syne2,Bcl9,Mmd,Ier2,Ptgs2,Mgat1,Ddx4,Cyfip1,Casz1,Tpi1,Rapgef2,Spn,Plscr1,Klf7,Cav1,Osm,Pbx1,Spire1,Dbnl,Samd9l,Itpr1,Tmeff1,Acod1,Il15ra,Cd164,Plcl2,Mmp9,Sirt1,Stat5a,Pdpn,Plagl1,Azi2,Golga3,Herc6,Kif5c,Apobec3,Arid4a,Socs3,Ifna2,Tnc,Med21,Slamf8,Slc30a1,Evl,Ccl2,Batf,Igsf9,Col18a1,Nupr1,Csf1,Il15,Antxr1,Spen,Ifrd1,Sipa1l1,Ptk2,Prag1,Etv6,Kdm5b,Prkx,Rac3,Nr1h3,Tle3,Pdgfrb,Cebpd,Ptpn2,Fzd5,Heatr9,Psma6,Gpc1,Slc25a25,Lif,Flt1,Arg2,Vcan,Odc1,Fpr2,Snx10,Eif4g2,Map2k1,Dock10,Nr3c1,Bcl2l11,Inhba,Tnfaip3,Rictor,Rap1gap2,Sphk1,Tcea1,Jak2,Errfi1,Rgs14,Akt3,Tnfrsf1b,Inpp5b,P2ry12,P2ry2,Cacybp,Sik3,Cdkn1a,Phf6,Rbbp8,Casp8,Pikfyve,Zfp513,Gys1,Katna1,Pla2g4a,Etv5,Vezt,Sdc4,Ifna6,Nck1,Acvrl1,Slc7a5,Srgn,Mosmo,Clic4,Stxbp3,Tmem67,Il12b,Agrn,Ifitm1,Ednrb,Ttc39c,Cnn2,Phgdh,Lox,Nfkb2,Acvr1b,Bmp2,Nrp2,Lhx2,Tnfsf9,Nfkb1,Rcn1,Keap1,Cdk5r1,Tet2,Diaph2,Il1b,Acp2,Btg2,Ifna1,Acp5 |
| 9.503e-14 | -29.98 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | MSigDB lists | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | 28 | 18 | 15632 | 1249 |
Map2k4,Nfkbil1,Tnfaip3,Cflar,Nfkb2,Traf2,Birc2,Casp8,Jun,Birc3,Tnf,Nfkbia,Ikbkg,Nfkb1,Tnfrsf1b,Nfkbie,Casp3,Nfkbib |
| 9.562e-14 | -29.98 | signal transduction | biological process | GO:0007165 | 4751 | 439 | 20694 | 1406 |
Sipa1l1,Rhoq,Dgkh,Spen,S1pr2,Gng11,Nupr1,Csf1,Il15,Hcar2,Gpr84,Fzd5,Ptpn2,Pdgfrb,Ccl8,Rac3,Prkx,Tle3,Nr1h3,Ptk2,Rnf34,Socs3,Ifna2,Azi2,Socs1,Pdpn,Eif2ak2,Gpr85,Map3k8,Stat5a,Ccl2,Batf,Nfkbia,Adrb2,Jak2,Lcp2,Tlr6,Errfi1,Sphk1,Rab19,Tyk2,Ddx58,Traf5,Irf7,Inhba,Rictor,P2ry14,Tnfrsf1b,Itga9,Rgs14,Akt3,Flt1,Lif,Asb13,Tnfsf15,Peli1,Bcl2a1a,Bcl2l11,Nr3c1,Pdk3,Trim12c,Dock10,Map2k1,Fpr2,Stat2,Ogfrl1,Daam1,Tnip3,Ednrb,Cd14,Bnip3,Ifitm1,Il12b,P2ry13,Sik3,Bcl2a1b,Mt2,P2ry2,P2ry12,Inpp5b,Arhgap26,Acvrl1,Agtrap,Gpr35,Nck1,Ifna6,Cdkn1a,Pikfyve,Spata13,Casp8,Ifnar1,Plat,Tlr3,Nfkbiz,Cdk5r1,Prkce,Ppp2r5a,Ppm1l,Nfkb1,Ifna1,Gpr141,Mlkl,Il1b,Isg15,Trib3,Pmaip1,G3bp2,Dusp1,Acvr1b,Nfkb2,Saa3,Tnfrsf8,Lox,Il2rg,Plek,Cpeb4,Nrp2,Bmp2,Casp2,Edn1,Sema4c,Cish,Gng12,Socs7,Dnaja1,Prkar2b,Fas,Lnpep,Dtx3l,Itga4,Sav1,Ogfr,Rhoc,Ccr3,Ptgir,Sgk3,Cmklr1,Plpp3,Irf1,Ppp1r15b,Map2k4,Cx3cr1,Rab21,Marco,Nfkbib,Gpr18,Zc3h12a,Il18,Prokr1,Traf2,Ifna5,Nek6,Mvp,Ripk2,Mul1,Tifa,Lrp4,Hivep2,Casp4,Nfkbil1,Dgka,Il18rap,Hap1,Ccne1,Casp1,Mtdh,Cd40,Irs2,Jmjd6,Arid5b,Il13ra1,Bambi,Cited2,Tnf,Mapkbp1,Plk3,Il1a,Daxx,Jun,Angpt1,Rras2,Caml,Ccl12,Rasgrp1,Atf3,Itpr1,Dbnl,Cxcl11,Cav1,Osm,Sirt1,Ccl22,Plcl2,Cd274,Il15ra,Lgals9,Ralgds,Cyfip1,Klf6,Gna15,Bcl9,Traf1,Pde7b,Ksr1,Plscr1,Rapgef2,Pik3cd,Spn,Cd86,Rap2c,Ppp1r12b,Adora2b,Ccrl2,Csrnp1,Csf3r,Pde1b,Ifih1,Dennd1b,Dock4,Dcp1a,Fcgr4,Pde5a,Myc,Htr2a,Ccl9,Olfr56,Znrf3,Iigp1,Cenpj,Mecp2,Phactr4,Tulp3,Vegfc,Rhou,Ccl7,Cxcl1,Fcgr1,Slc9a1,Pf4,Apaf1,Tlr9,Ddit4,Scyl2,Maml2,Ezr,Flrt3,Stat1,Rin2,Crkl,Cysltr2,Ripk3,Trib1,Cxcl3,Il12rb1,Gnb4,Cxcl10,Ptafr,Ero1l,Ebi3,Pdgfb,Klrk1,Ikbke,Lpar1,Ggct,Src,Stat3,Hck,Gpr68,Sema3c,Lcn2,Rapgef5,Vcam1,Fut8,Egr1,Tagap,Rab10,Calcrl,Notch2,Ppp1r15a,Bcl6,Gdf15,Il1rn,Rnd1,Mark2,Rcan1,Kdr,Nlrc5,Ubash3b,Cx3cl1,Mdfic,Pilra,Cacna1d,Kitl,Met,Serp1,Myd88,Ift57,Fcgr2b,Casp3,Itgav,Gja1,Ikbkg,Rhof,Ccnd1,Nr4a3,Relb,Pdgfc,Mdm2,Gpr132,Dtx2,Hmga2,Mapkapk2,Itga5,Hif1a,Il6,Jag1,Prnp,Plk2,Mt1,Cacnb3,Grk3,Gem,Rel,Sema4a,Stap1,Homer1,Lrp8,Adap2,Nfkbid,Flrt2,Nod2,Zfp36,Irak3,Itgb8,Ptger4,Aim2,Adora2a,Adgrg6,Cdc42ep4,Rgl1,Acvr1,Plaur,Nr4a1,Adgre4,Uaca,Clec4e,Rnd3,Pim1,Tlr2,Clec4d,Hmox1,Themis2,Plpp1,Itgal,Tiparp,Irak2,Cd300lf,Rhoh,Notch1,Rgs1,Cxcl9,Nos2,Sesn3,Ifna4,Irgm2,Icosl,Cdc42ep2,Dyrk2,Gcnt2,Gng4,Map4k4,Tlk2,Nmi,Ptprj,Xcr1,Phip,Nox1,Map3k6,Fgr,Igf1r,Larp1,Cxcl2,Ccl5,Ifnb1,Nod1,Malt1,Fpr1,Rnf31,Pde4b,Oas2,Ift22,Tlr1,Cd74,C3,Ccl4,Stat4,Syk,Pde3b,Ccl3,Ifi204,Sod2,Fzd1,Rab20,Col4a2,Pik3r5,Zyx,Ccr1,Pml,Slc39a4,Htr2b,Ptch1,Rab32,Sdc1,Ahr,Clcf1,Lyn,Kremen1,Tnip1,Il4ra,Ier3,Arf4,Pik3r6,Hhex,Hp,Gpsm2,Axl,Acsl1,Atm,Cd80,Bcl2a1d,Abr,Fos,Rab9,Tank,Cd38,Rgs3,Adgrl2,Stoml1,Arhgef3 |
| 9.615e-14 | -29.97 | positive regulation of proteolysis | biological process | GO:0045862 | 342 | 64 | 20694 | 1406 |
Tmem67,Antxr1,Fas,Nupr1,Nod1,Dnajb2,Malt1,Mmp25,Myc,Mefv,Gclc,Mmp14,Ptk2,Cop1,Rnf19b,Hspa1a,Syk,Plk3,Tnf,Aim2,Fam162a,Tnfsf10,Ift57,Apaf1,Rnf19a,Casp8,Pml,S100a8,Nlrc4,Jak2,Stat1,Uaca,Psmd10,Tnip1,Trib1,Lyn,Cav1,Cycs,Sirt1,Psme1,Rnf139,Tnfrsf1b,Zc3h12a,Mdm2,Nlrp3,Il1b,Pmaip1,Trib3,Psme2,Ankib1,Rnf14,Cflar,Tnfsf15,Mul1,Ripk2,Src,Hspa1b,Bcl2l11,Tank,Stat3,Plk2,Casp4,Ctsc,Casp1 |
| 9.724e-14 | -29.96 | regulation of viral process | biological process | GO:0050792 | 183 | 44 | 20694 | 1406 |
Cd74,Trim13,Zc3hav1,Notch1,Isg15,Nectin2,Chmp4b,Oas1b,Ifitm1,Zfp36,Zc3h12a,Ifnb1,Oas1g,Pcx,Trim30a,Adar,Trim14,Ccl5,Larp1,Stau1,Resf1,Trim21,Stat1,Isg20,Trim56,Pml,Parp10,Trim26,Hdac1,Plscr1,Oas3,Rsad2,Oasl2,Jun,Shfl,Eif2ak2,Mdfic,Tnf,Oasl1,Fam111a,Slpi,Apobec3,Oas1a,Ccl4 |
| 9.786e-14 | -29.96 | GSE17721_POLYIC_VS_CPG_12H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_12H_BMDC_UP | 171 | 46 | 15632 | 1249 |
Prdm9,Tlr3,Tnfsf10,Gca,Dio2,Slc12a9,Csrp1,Caml,Snx2,Spint2,Tbc1d13,Ch25h,Mthfr,Myd88,Bfar,Rhoc,Klf6,Sat1,Glipr2,Tmod3,Irf1,Pik3cd,Arf4,Kdr,Cd300lf,Asf1a,Nfil3,Casp4,Stat4,Tmem176b,Egr1,Kat2b,Pttg1,Gmppb,Mul1,Aldh1b1,Fbxo4,Angpt1,Atp11b,Dnase1l3,Flt1,Tmem184b,Nat2,Slc44a1,Ap3b1,Triobp |
| 9.872e-14 | -29.95 | GO_CELL_MOTILITY | MSigDB lists | GO_CELL_MOTILITY | 762 | 121 | 15632 | 1249 |
Prkx,Thbs1,Bambi,Pf4,Vegfc,Cxcl10,Il12b,Slc7a5,Inpp5b,Pdgfb,Tyk2,Slc7a8,Rhoc,Hck,Notch1,Pml,Itga4,Ier2,Fgr,Sell,Icam1,Hif1a,Spata13,Fut8,Acvrl1,Acvr1,Insl6,Src,Axl,P2ry12,Kdr,Socs7,Trem1,Stat1,Nox1,Pik3cd,Sema4a,Procr,Itgal,Il10,Plau,Angpt1,Atp2b4,Mark2,Ccl22,Ccl2,Pdpn,Il6,Edn1,Cxcl14,Sdc2,Sbds,Slc7a11,Ccl12,Flrt3,Cx3cr1,Flt1,Dock4,Kitl,Plat,Vcam1,Cxcl1,Il1b,Htr2b,Arid5b,Ddit4,Cxcl2,Rapgef2,Gja1,Ccl5,Pde4b,Ccr1,Map2k1,Pdgfrb,Ccl3,Asap3,F11r,Cd74,Sele,Slc16a3,Tnf,Csf3r,Ccl4,Fscn1,Arf4,Jak2,Mmp9,Itga5,Sema4c,Egr3,Ptk2,Lyn,Ddx4,Lpar1,Itga9,Slc9a1,Pstpip2,Syne2,Ednrb,S100a8,Cav1,Sema3c,Slc16a1,Tspo,Sdc4,Cd34,Olr1,Palld,Nck1,Cx3cl1,Cdk5r1,Sdc1,Mmp14,Parp9,Phactr4,Vcan,Itgav,Syk,Spn,Nr4a1,Dnaja1 |
| 1.012e-13 | -29.92 | Innate Immune System | REACTOME pathways | R-MMU-168249 | 1177 | 175 | 8608 | 757 |
Atp6v1d,Clec4d,Ppp2r1b,Prkce,Zbp1,Fcgr2b,Armc8,Casp1,Psme2b,Fcgr4,Cd55,Pnp2,Klrk1,Psmd10,Map2k1,Rnaset2a,Map3k8,Tnfrsf1b,Bst1,Cdkn1a,Ifnb1,Irak2,Sell,Cd300e,Fcgr1,Ifna4,Pde1b,Rnaset2b,Nos2,Ptafr,Ctsc,H2-T22,Il1b,Rab10,Phlpp2,Angpt1,Fpr1,Cxcl1,Plaur,Apaf1,Ikbke,Psmb9,Cyfip1,Mefv,Nlrp3,Myd88,Hspa1b,Relb,H2-Q4,Irf7,Itgav,Pdgfrb,Ifna2,Ksr1,Tlr6,Nfkbia,Dync1h1,Plau,S100a8,Irs2,Rictor,Fos,Ampd3,Tlr3,Dusp6,Serpina3f,Trim56,Gpr84,Atp11b,Rapgef2,Met,Psmb8,Ripk2,Atp11a,Nr4a1,Peli1,Ifna5,Lyn,Fgl2,Tlr9,Gca,Nod2,Lcp2,Fgr,Jun,Nfkb2,Pdzd11,Pik3cd,Ifna6,Hp,Clec4n,H2-T24,Psmb10,Hk3,Myo10,Jak2,Mmp9,Cd86,Olr1,Actb,Plac8,Ppp2r5a,Tab2,Ubr4,Tarm1,Dusp4,Pgm1,Aim2,Psmb6,H2-T10,Psme1,Nod1,Fpr2,H2-Q7,Cd80,Trem1,Ptk2,Ier3,Tlr2,Casp8,H2-Q6,Tnfaip3,Nfkbib,Syk,Ptprj,Tlr1,Rap2c,Src,Cxcl3,Dbnl,Rhof,C1ra,Map2k4,Nfkb1,Spred1,Enpp4,Irf2,Clec5a,Mapkapk2,Acpp,Cd14,Cd180,H2-M2,Malt1,Phlpp1,Mmp25,Hvcn1,Nck1,Ikbkg,Mvp,Trim21,Cnn2,Ifna1,Irf1,Il2rg,Cxcl2,Gsdmd,Pdgfb,Pfkl,Kitl,Txn1,Serpinb6b,Prkar2b,Dusp5,C3,Rasgrp1,Slpi,Psme2,Tax1bp1,Psma6,Trib3,Lcn2,Ddx58,Mdm2,Itgal |
| 1.113e-13 | -29.83 | localization of cell | biological process | GO:0051674 | 952 | 127 | 20694 | 1406 |
Gpc1,Lpar1,Flt1,Cxcl10,Vcan,Pdgfb,Cxcl9,Map2k1,Pvr,Xcr1,Egr3,Src,Sema3c,Tnfaip3,Sbds,Cxcl3,Flrt3,Crkl,Notch1,Sele,Itga9,Pdpn,Ccl7,Tspo,Cxcl1,Mcoln2,Phactr4,Atp2b4,Acvr1,Sdc2,Nr4a1,Ddit4,S100a8,Cx3cr1,Ccl2,Plau,Slamf8,Pf4,Lrp8,Dock4,Carmil1,Ccrl2,Csf3r,Sema4c,Socs7,Dnaja1,Rac3,Ccl9,Prkx,Ch25h,Prag1,Itgb8,Rhoc,Ccr3,Mmp14,Ptk2,Pdgfrb,Myo10,Itga4,Ccl8,Saa3,Lox,Syne2,Ier2,Hif1a,Ddx4,Sema4a,Trem1,Rapgef2,Nrp2,Pik3cd,Thbs1,Spn,Cd34,Sdc1,Cxcl11,Cdk5r1,Sell,Gja1,Htr2b,Itgav,Asap3,Rhof,Plat,Il1b,Axl,Palld,Ccl22,Arf4,Tnf,Cx3cl1,Ccl3,P2ry12,Inpp5b,Kitl,Bambi,Kdr,Ccl4,Syk,Ccl12,Katna1,Sdc4,Abcc1,Spata13,Ccr1,Pml,Gpr35,Acvrl1,Met,Nck1,Pstpip2,Cxcl2,Ccl5,Icam1,Cxcl14,Nox1,Vcam1,Fut8,Il1rn,Il12b,Mark2,Actb,Ednrb,Fscn1,Pde4b,Insl6,Arid5b |
| 1.113e-13 | -29.83 | cell motility | biological process | GO:0048870 | 952 | 127 | 20694 | 1406 |
Mmp14,Ptk2,Ch25h,Prkx,Rac3,Ccl9,Prag1,Itgb8,Rhoc,Ccr3,Itga4,Myo10,Ccl8,Pdgfrb,Carmil1,Lrp8,Dock4,Socs7,Dnaja1,Ccrl2,Csf3r,Sema4c,S100a8,Cx3cr1,Acvr1,Sdc2,Nr4a1,Ddit4,Slamf8,Pf4,Plau,Ccl2,Tspo,Cxcl1,Pdpn,Ccl7,Mcoln2,Phactr4,Atp2b4,Sele,Notch1,Itga9,Tnfaip3,Sbds,Cxcl3,Crkl,Flrt3,Pvr,Xcr1,Map2k1,Sema3c,Egr3,Src,Lpar1,Gpc1,Pdgfb,Cxcl9,Flt1,Cxcl10,Vcan,Mark2,Il1rn,Il12b,Fscn1,Pde4b,Insl6,Arid5b,Actb,Ednrb,Cxcl2,Ccl5,Icam1,Fut8,Cxcl14,Nox1,Vcam1,Spata13,Ccr1,Pml,Ccl12,Katna1,Abcc1,Sdc4,Nck1,Pstpip2,Acvrl1,Gpr35,Met,P2ry12,Kitl,Inpp5b,Tnf,Cx3cl1,Ccl3,Syk,Bambi,Kdr,Ccl4,Axl,Il1b,Ccl22,Arf4,Palld,Sell,Sdc1,Cxcl11,Cdk5r1,Plat,Htr2b,Gja1,Itgav,Rhof,Asap3,Sema4a,Rapgef2,Thbs1,Nrp2,Pik3cd,Spn,Cd34,Trem1,Syne2,Ier2,Saa3,Lox,Ddx4,Hif1a |
| 1.122e-13 | -29.82 | positive regulation of protein secretion | biological process | GO:0050714 | 301 | 59 | 20694 | 1406 |
Ifnar1,Gja1,Htr2b,Jak2,Frmd4a,Prkce,Tlr2,Ddx58,Clec4e,Il4ra,Osm,Tnfrsf14,Sirt1,Clec4n,Cd274,Nlrp3,Il1b,Lgals9,Hif1a,Il6,Tnfsf15,Ripk2,Src,Clec5a,Cd34,Gpr68,Cd38,Casp4,Sec24a,Casp1,Ifih1,Fgr,Nlgn2,Rgcc,Hcar2,Hk1,Irs2,Nod2,Cd14,Fzd5,Gsdmd,Tlr1,Mmp13,Syk,Ptger4,Vegfc,Ccl3,Adora2a,Il1a,Aim2,Tnf,Cacna1d,Serp1,Tnfsf4,Glrx,Rasgrp1,Arid5a,Il10,Ezr |
| 1.127e-13 | -29.81 | leukocyte differentiation | biological process | GO:0002521 | 369 | 67 | 20694 | 1406 |
Rhoh,Hhex,Axl,Ifna1,Sirt1,Cd300lf,Plcl2,Pou2f2,Fam20c,Clec4e,Ahr,Gpr18,Clcf1,Ripk3,Tlr2,Clec4d,Lyn,Tnfaip3,Relb,Ptprj,Tnfsf8,Dock10,Sema4a,Snx10,H2-Ab1,Tnfsf9,Stat3,Csf3,Src,Spn,Batf2,Ifna4,Bcl2a1d,Ifna5,Il6,Atm,Il12b,Cd74,Fzd5,Malt1,Ptpn2,Irf4,Junb,Bcl6,Gadd45g,Csf1,Egr1,Fas,Il15,Notch2,Jmjd6,Ifnb1,Casp8,Batf,Irf1,Ikzf1,Ifna6,Slamf8,Tnf,Jun,Rsad2,Stat5a,Ifna2,Azi2,Cited2,Syk,Ptger4 |
| 1.138e-13 | -29.80 | negative regulation of cell population proliferation | biological process | GO:0008285 | 677 | 100 | 20694 | 1406 |
Spint2,Stat1,Jak2,Hmox1,Tlr2,Cd200,Ptges,Tarm1,Inhba,Trib1,Tnfaip3,Rnf139,Optn,Notch1,Slfn2,Arg2,Flt1,Slfn3,Lif,Stat3,H2-Ab1,Peli1,Map2k1,Ptprj,Jarid2,Fas,Il15,Nupr1,Dnajb2,Spry2,Fzd5,Ptpn2,Myc,Pde5a,Ptgir,Sav1,Zeb1,Morc3,Eef1e1,Vegfc,Slfn1,Eif2ak2,Adora2a,Pdpn,Tspo,Irf1,Hdac1,Intu,Il10,Dach1,Ptch1,Gja1,Casp3,Ahr,Lyn,Cav1,Tnfrsf14,Mmp9,Etv3,Btg2,Cd274,Il1b,Pmaip1,Lgals9,Pttg1,Dusp1,Cd80,Atm,Il6,Ptgs2,Fbxo4,Prnp,Spn,Thbs1,Rapgef2,Bmp2,Cd86,Adora2b,Rgcc,Kat2b,Cdkn2d,Bcl6,Il12b,Cited2,H2-Aa,Sh3bp4,Il1a,Tnf,Jun,Sod2,Acvrl1,Ift57,Prdm1,Pim2,Sdc4,Fcgr2b,Parp10,Ccl12,Pml,Cdkn1a |
| 1.176e-13 | -29.77 | GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | 218 | 53 | 15632 | 1249 |
Casp8,Csf1,Zeb1,Tmem176a,Rasgrp1,Egr3,Tnfsf4,Trib1,Irf1,Lyn,Hcls1,Syk,Fos,Ptpn2,Jun,Irf4,Mmp14,Il6,Myc,Ap3b1,Ifnb1,Tmem176b,Fas,Ubash3b,Nlrp3,Il4ra,Il15,Il27,Cd80,Ccr1,Ccl5,Cd86,Irf7,Pik3r6,Nfkbid,Il12rb1,Inhba,Tlr3,Ripk2,Il12b,Kitl,Il1b,Pf4,Tnf,Axl,Bcl6,Pnp2,Gpr68,Hlx,Prdm1,Lif,Cd74,Cd83 |
| 1.185e-13 | -29.76 | GO_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 95 | 33 | 15632 | 1249 |
Nod1,Apaf1,Ifi207,Fas,Pml,Nlrp3,Ifi214,Mul1,Casp3,Cycs,Ift57,Tnf,Ifi213,Bcl2l11,Casp1,Nlrc4,Traf2,Ifi209,Ifi205,Jak2,Tnfsf10,Fam162a,Casp7,Ifi204,Ifi211,Ifi208,Tnfsf15,Casp2,Egln3,Ifi203,S100a8,Mndal,Casp8 |
| 1.221e-13 | -29.73 | MODULE_177 | MSigDB lists | MODULE_177 | 106 | 35 | 15632 | 1249 |
Ifi209,Ifi205,Ifi213,Nfkbia,Gypc,Nr3c1,Ifi214,Il4ra,Ifi207,Tnfaip3,Cd83,Sla,Cnp,Itgal,Ifit3,Mndal,Nfkb1,Dusp6,Oas1a,Ifi203,Tyk2,Isg20,Ifi211,H2-Aa,Ifi208,Nmi,Ifi204,Il2rg,Ifit3b,St3gal1,Oas1g,Glrx,Dek,Hcls1,Rgs1 |
| 1.247e-13 | -29.71 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | 147 | 42 | 15632 | 1249 |
Slamf7,Cd38,Samhd1,Ahr,Lif,Palld,Mcoln2,Usp18,Atp11a,Isg15,Mpp7,Ikzf1,Irf4,Ifi44,Fgl2,Rsad2,Dusp4,Ifit1bl1,Ifit2,Bcl2l11,Gpr18,Oas3,Adam19,Tnfsf10,Thbs1,Epsti1,Cmpk2,Prkar2b,Atp10a,Oasl1,Stat1,Ptgs2,Ifit3b,Clec4d,Flnb,Xaf1,Oas2,AA467197,Ifit1bl2,Ifit3,Hopx,Gem |
| 1.258e-13 | -29.70 | GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN | MSigDB lists | GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN | 185 | 48 | 15632 | 1249 |
Pdk3,Birc3,Il10,Casp4,Zfp36,Plscr1,Flnb,Il13ra1,Itga5,Pik3cd,Jak2,Tax1bp1,Dusp16,Cyfip1,Msr1,Tor1aip2,Mmp14,Peli1,Egr1,Nr1h3,Irs2,Clec4e,Ahr,Olr1,Nampt,Gch1,Col11a2,Irf7,Phlda1,Bst1,Ptger4,Rnf19b,Kcna3,Rcan1,Ptgs2,Cdc42ep4,Clic4,Rcl1,Dusp1,Tnf,Ehd1,Rhoq,Prdx5,Prdm1,Spata13,Atp11a,Apaf1,Mdfic |
| 1.258e-13 | -29.70 | GSE23925_DARK_ZONE_VS_NAIVE_BCELL_DN | MSigDB lists | GSE23925_DARK_ZONE_VS_NAIVE_BCELL_DN | 185 | 48 | 15632 | 1249 |
Fos,Bcl2l11,Bcl2a1b,Nr4a1,Dusp2,Cdk5r1,Pttg1,Etv3,Egr1,Nfkbiz,Pim3,Lmo4,Gem,Ppp1r15b,Cd69,Leng9,Zfp36,Pik3cd,Trib1,Itpkc,Egr3,Ccl4,Hcls1,Arid5a,Tnf,Dusp1,Bcl2a1d,Egr2,Ccdc86,Oaf,Csrnp1,Ier2,Plk3,Tnfaip3,Ncoa7,Sla,Fosb,Col11a2,Csrp1,Gch1,Dusp6,Junb,Maff,Nfkbid,Arl5b,Phf6,Dusp5,Bcl2a1a |
| 1.291e-13 | -29.68 | GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | MSigDB lists | GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 395 | 77 | 15632 | 1249 |
Htra1,Rasgrp1,Leng9,Rabgef1,Birc3,Il10,Nos2,Clcf1,Trem1,Tnfsf4,C3,Itpkc,Lyn,Irf4,Stap1,Il6,Ifnb1,Eif2ak2,Ifit1bl1,H2-Q4,Spn,Syk,Ccl12,Il27,Il15,Cd80,Tnfrsf14,Tap1,Zc3hav1,Angpt1,Ddx60,Abr,Il4ra,Nlrp3,Mul1,Il12rb1,Fcgr4,Ifit1bl2,Cd86,Fzd5,Pik3r6,Elmod2,Il1b,Tlr3,Cd55,Ripk2,Traf3ip2,Zc3h12a,Hmox1,Adora2b,Nr4a3,Il12b,Serpinb9,Ptafr,Dhx58,Rsad2,Tnf,H2-Q6,Traf2,Ankrd17,Birc2,Bcl6,Cd40,Ripk3,Hck,Tnfaip3,Irak3,H2-Q7,Malt1,Aim2,Hlx,Pml,Icam1,Ddx58,Stat2,Cd74,Fgr |
| 1.371e-13 | -29.62 | regulation of cellular catabolic process | biological process | GO:0031329 | 679 | 100 | 20694 | 1406 |
Psmd10,Ikbkg,Htr2b,Hk2,Il1b,Polr2g,Dram1,Acsl5,Mapkapk2,Trib3,Hp,Trim13,Psme1,Sirt1,Btg2,Mdm2,Ankib1,Hif1a,Psme2,Kdm4a,Tent4a,Il6,Atm,Ctsc,Hspa1b,N4bp1,Plk2,Irs2,Nod1,Tmem67,Larp1,Mtdh,Gclc,Mefv,Carhsp1,Bnip3,Plk3,Tnf,Kdr,Sh3bp4,Ric1,Pim2,Caml,Pml,Pikfyve,Nampt,Noct,Myd88,Irgm1,Rnf19a,Tlr2,Hmox1,Trib1,Tnfaip3,Timp1,Chmp4b,Zc3hav1,Rnf139,Zc3h12a,Tnfrsf1b,Optn,Rnf14,Irgm2,Sesn3,Ripk2,Mul1,Usp25,Map2k1,Ldlr,Tlk2,Eif4g2,Casp1,Bcl2l11,Stat3,Nupr1,Dnajb2,Nod2,Trim21,Tent2,Ptk2,Cop1,Rnf19b,Zfp36,Htr2a,Dtx3l,Myc,Pnpt1,Tspo,Iigp1,Hspa1a,Plekhn1,Atp2b4,Mov10,Sco1,Il10,Ezr,Apaf1,Dcp2,Tlr9,Adrb2 |
| 1.386e-13 | -29.61 | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDC_DN | 192 | 49 | 15632 | 1249 |
Slfn3,Ralgds,Ptges,Slc31a1,Chic2,Rab10,Tmeff1,Oas2,Maff,Snx10,Rgl1,Samsn1,Slfn4,Ppp1r15a,Batf,Mdfic,Arg2,Ifih1,Nr3c1,Hdac1,Esd,Lhx2,Frmd6,Wdr43,Cd200,Denr,Ier3,Cnn3,Atxn7l1,Plscr1,Hat1,Birc3,Tnfrsf1b,Hinfp,Rnd3,Col4a2,Me1,Slc28a2,Atf3,Gbe1,Irgm2,Dusp2,Mmp14,Rai14,Peli1,Cpd,Flt1,Morc3,Ets2 |
| 1.388e-13 | -29.61 | LI_INDUCED_T_TO_NATURAL_KILLER_UP | MSigDB lists | LI_INDUCED_T_TO_NATURAL_KILLER_UP | 275 | 61 | 15632 | 1249 |
Tnfsf10,Irak2,Cldnd1,Gcnt2,Osbpl3,Pilrb1,Glrx,Dusp5,Pdlim7,Slc2a6,AA467197,Stx11,Hk2,Dusp6,Ccl5,Junb,Osm,Hopx,Batf,Mvp,Hvcn1,Hhex,Traf1,St3gal6,Rab19,Upp1,Slc39a4,Cish,Mlkl,Gpr68,Errfi1,Glipr2,Casp1,Tnf,Rgs1,Ccl4,Rbms1,Cdkn1a,Lrrc8c,Nfil3,Egr3,Endod1,Hmgcs1,Sema4a,Ier3,Plscr1,Cd69,Nfkb1,Slamf7,Tspo,Gpc1,Pilrb2,Pim3,Egr1,P2ry14,Ccnd2,Samd9l,Gadd45g,Cx3cr1,Rhof,Gpr18 |
| 1.448e-13 | -29.56 | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_C57BL6_UP | MSigDB lists | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_C57BL6_UP | 160 | 44 | 15632 | 1249 |
Glrx,Cdkn1a,Gcnt2,Ikbke,Plat,Thbs1,Ifi204,Slc43a3,Dnajb4,Mafg,Inhba,Ifi203,Btg2,Ifi211,Ifi208,Cd274,Mndal,Junb,S100a8,Nfkb1,Ahrr,Ifi207,Prdx1,Pim3,Batf,Rbms2,Gclc,Slamf7,Klf8,Icam1,Irs2,Ifi214,Socs1,Lif,Fut8,Pla2g4a,Rnf24,Ifi209,Ifi205,Tnf,Gadd45b,Ifi213,Agrn,Casp1 |
| 1.519e-13 | -29.52 | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP | MSigDB lists | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP | 75 | 29 | 15632 | 1249 |
Lcp2,Plek,Nampt,Nfkb1,Cxcl2,Zfp36,Trib1,Mthfd2,Ier3,Egr3,Tfec,Il1b,Ppp2r2a,Cflar,Cxcl1,Bcl2a1a,Clcn7,Idi1,Gpr18,Ets2,Hmga1,Tank,Tnf,Ccl12,Bcl2a1b,Bcl2a1d,Upp1,Ahr,Plau |
| 1.519e-13 | -29.52 | GNF2_CD53 | MSigDB lists | GNF2_CD53 | 75 | 29 | 15632 | 1249 |
Tap1,Phf11c,Ifi207,Phf11a,Myd88,Crlf3,Ifi214,Psmb10,Sell,Psme1,H2-Q7,Tapbp,Ifi209,Ifi205,Psmb9,H2-Q6,H2-Q4,Phf11b,Ifi213,Sp110,Hcls1,Pik3cd,Phf11d,Ifi204,Ifi203,Ifi208,Ifi211,Mndal,Psmb8 |
| 1.538e-13 | -29.50 | GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_UP | MSigDB lists | GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_UP | 154 | 43 | 15632 | 1249 |
Sp110,Il2rg,Ifi204,Oas1g,Oasl1,Stat1,Larp1,Ifi35,Herc6,Xaf1,Parp12,Ifi203,Oas2,Oas1a,Slc25a12,Stoml1,Ifi208,Trim14,Isg20,Ifi211,Mndal,Irf7,Klf2,Brd2,Lnpep,Ifi207,Adar,Zbp1,Smg7,Isg15,Ifi214,Trim12c,Pml,Ddx60,Rsad2,Ifi44,Bbx,Tcf4,Ifi209,Ifi205,Oas3,Eif2ak2,Ifi213 |
| 1.567e-13 | -29.48 | GSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | 186 | 48 | 15632 | 1249 |
Tnfaip3,Gbp2,Hck,Crim1,Rgs3,Cd164,Nod1,Rhbdf2,Tnf,Bcl2a1d,Egr2,Serpinb9,Oas1g,Fam53c,Lacc1,Ikbke,Bcl2a1a,Sipa1l1,Irf7,Tyk2,Uba7,Stx11,Atf3,Tnfrsf14,Lpcat2,Slc16a1,Mrpl52,Cyfip1,Bcl2a1b,Nfkbia,Il6,Sema4a,Ier3,Dnajb4,Rcn1,Odc1,Ptk2,Endod1,Cd300lf,Tnip1,Itgal,Il10,Atm,S100a8,Abtb2,Il18rap,Oas1a,Plscr1 |
| 1.638e-13 | -29.44 | regulation of catabolic process | biological process | GO:0009894 | 822 | 114 | 20694 | 1406 |
Irs2,Nod1,Mtdh,Larp1,Tmem67,Gclc,Mefv,Bnip3,Carhsp1,Plk3,Tnf,Sh3bp4,Ric1,Pde3b,Kdr,Pml,Nampt,Pikfyve,Caml,Pim2,Rnf19a,Irgm1,Myd88,Noct,Trim30a,Prkce,Psmd10,Hk2,Gja1,Htr2b,Samd9l,Ikbkg,Trib3,Trim13,Hp,Acsl5,Polr2g,Dram1,Mapkapk2,Il1b,Ppp2r3a,Btg2,Mdm2,Arel1,Ier3,Sirt1,Psme1,Ankib1,Il6,Atm,Tent4a,Kdm4a,Psme2,Hif1a,Ctsc,Plk2,N4bp1,Hspa1b,Dnajb2,Nod2,Nupr1,Hcar2,Tent2,Trim21,Cop1,Rnf19b,Ptk2,Myc,Dtx3l,Irak3,Htr2a,Zfp36,Tspo,Pnpt1,Atp2b4,Mov10,Hspa1a,Plekhn1,Iigp1,Il10,Ezr,Sco1,Ddit4,Adrb2,Tlr9,Dcp2,Apaf1,Trib1,Tnfaip3,Tlr2,Hmox1,Timp1,Zc3hav1,Chmp4b,Tiparp,Optn,Zc3h12a,Tnfrsf1b,Rnf139,Mul1,Ripk2,Irgm2,Sesn3,Rnf14,Nos2,Usp25,Odc1,Casp1,Eif4g2,Tlk2,Ldlr,Map2k1,Stat3,Bcl2l11 |
| 1.657e-13 | -29.43 | BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | MSigDB lists | BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | 142 | 41 | 15632 | 1249 |
Ttc39b,Nr4a3,Etnk1,Ell2,Pcgf5,Dusp5,Slc37a3,Trafd1,Il1b,Gfi1,Fam102b,Lcp2,Rrs1,Stat4,Spint2,Cd69,Cysltr2,Csf1,Tab2,Ccl22,Rab19,Slco3a1,Il4ra,Socs1,Nfkbiz,Lif,Tnfrsf14,Batf,Cd83,Eno1,Bcl6,Klf3,Taf4b,Cers6,Dusp4,Ikzf1,Tbc1d1,Casp3,Irf4,Stap1,Cish |
| 1.702e-13 | -29.40 | GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_DN | MSigDB lists | GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_DN | 167 | 45 | 15632 | 1249 |
Pgm1,Il15,Tnfrsf14,Gramd1a,Trip10,Ppa1,Dtx2,Rab20,Irf1,Ccl4,Cd300lf,Tnfaip2,Rgs1,Fscn1,Orai2,Prkar2b,Cdkn1a,Tagap,Nfkb1,Tor3a,Birc3,Flnb,Ampd3,Isg20,Prdm1,Marcksl1,Gbp3,Cst7,Cd40,Rhbdf2,Tbc1d1,Acvrl1,Nfkbie,Tlr3,Il18,Nfkb2,Ikbke,Trafd1,Il1b,Jarid2,Cd274,Slc7a5,Gpr132,Wars,Nfkbid |
| 1.702e-13 | -29.40 | GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_DN | MSigDB lists | GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_DN | 167 | 45 | 15632 | 1249 |
Phf11c,F10,Cd80,Phf11a,Gpr141,Chst11,Dusp4,Stap1,Gadd45b,Dusp16,Cdkn1a,Gbp2b,Odc1,Phf11d,Gpd2,Dgkh,Ell2,Pla2g7,Smpdl3b,Cysltr2,Gda,Hif1a,Mxd1,Prdm1,Arhgap26,Ogfrl1,Casp3,Carhsp1,Homer1,Phf11b,Insl6,Glrx,Prkx,Clec5a,Cxcl10,Nsmaf,Ttc39b,Ptger4,Ptprj,Sap30,Phlda1,Samsn1,Ccr1,Snx10,Myadm |
| 1.774e-13 | -29.36 | ZHENG_BOUND_BY_FOXP3 | MSigDB lists | ZHENG_BOUND_BY_FOXP3 | 453 | 84 | 15632 | 1249 |
Sell,Rab19,Hif1a,Prrg4,Rhoh,Aim2,Prdm1,Irf2,Malt1,Mdfic,Tnfaip3,Rab3ip,Bcl6,Arhgef3,Axl,Klf6,Parp8,Dock10,Mdm2,Gbp4,Gbp9,Map3k8,Ttc39b,Arid5b,Nsmaf,Nr4a3,4930453N24Rik,Ptger4,Vps54,Klf2,Samsn1,Map4k4,Dusp6,Pde4b,Jarid2,Olfr56,AA467197,Ext1,Arl4a,Ubash3b,Etv3,Tlr6,Fas,Nfkbiz,Samhd1,Ahr,Rbl1,Zc3hav1,Hk3,Rras2,Herc3,Cited2,D16Ertd472e,Gpr18,Cx3cr1,Hivep2,Klf3,Ift57,Lrch1,Peli1,Irf4,Rcsd1,Gpd2,Ifit3b,Parp11,Ms4a6d,Trib1,Cd200,Etnk1,Prkar2b,Lrrc8c,Rgs1,Ust,Adam19,Tmem67,Znrf1,Sik3,Ifit3,P4ha1,Abtb2,Eef1e1,Cd69,Syne2,Stat4 |
| 1.780e-13 | -29.36 | taxis | biological process | GO:0042330 | 499 | 81 | 20694 | 1406 |
Evl,Pf4,Slamf8,Met,Ccl2,Angpt1,Gpr35,Ccr1,Cx3cr1,S100a8,Abcc1,Ccl12,Nr4a1,Vegfc,Syk,Egr2,Ccl4,Kif5c,Cmklr1,Cxcl1,Ccl7,Ccl3,Cx3cl1,Ccl8,Pde4b,Fpr1,Ednrb,Pdgfrb,Ccr3,Ccl9,Il1rn,Ch25h,Agrn,Nlgn2,Sema4c,Vcam1,Ccrl2,Cxcl14,Ext1,Ntng2,Csf3r,Flrt2,Dock4,Cxcl2,Ccl5,Lhx2,Sema3c,Nrp2,Pik3cd,Trem1,Egr3,Sema4a,Xcr1,Fpr2,Ptprj,Pdgfb,Cxcl9,Cyfip1,Scn1b,Ptafr,Flt1,Cxcl10,Lpar1,Vasp,Lox,Saa3,Ccl22,Itga9,Palld,Lgals9,Il1b,Crkl,Flrt3,Itgav,Ptch1,Cxcl3,Sbds,Klf7,Cdk5r1,Nr4a3,Cxcl11 |
| 1.780e-13 | -29.36 | DIRMEIER_LMP1_RESPONSE_LATE_UP | MSigDB lists | DIRMEIER_LMP1_RESPONSE_LATE_UP | 52 | 24 | 15632 | 1249 |
Plek,Nfkb1,Tnfrsf1b,Slc7a5,Piezo1,Hmox1,Mthfd2,Lyn,Serpinb9,Cflar,Fscn1,Tnip1,Nfkb2,Stip1,Stat5a,Sqstm1,Swap70,Trip10,Cd40,Ccl22,Traf1,Il4ra,Batf,Mdfic |
| 1.798e-13 | -29.35 | negative regulation of cell-cell adhesion | biological process | GO:0022408 | 186 | 44 | 20694 | 1406 |
Fgl2,Swap70,Zc3h12a,Cd274,Lgals9,Spint2,Jak2,Casp3,Myadm,Il4ra,Tarm1,Tnfaip3,Tnfrsf14,Peli1,H2-Ab1,Prnp,Spn,Map2k1,Ass1,Bmp2,Cd86,Arg2,Cd80,Jag1,Hlx,Ptpn2,Pde5a,Bcl6,Il1rn,Ptk2,Cd74,Rgcc,Ifnb1,Nfkbid,Irf1,Adrb2,Tnfsf4,Sdc4,Il10,H2-Aa,Ubash3b,Adora2a,Slfn1,Socs1 |
| 1.847e-13 | -29.32 | BERENJENO_TRANSFORMED_BY_RHOA_UP | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_UP | 494 | 89 | 15632 | 1249 |
Dusp6,Gja1,Serpine1,Rrs1,Cacybp,Higd1a,Sap30,Inhba,Adora2b,Pgk1,Pkp4,Stip1,Rcl1,Txnrd1,Ifit2,Cycs,Tnc,Errfi1,Tnfaip3,Tmem176a,Mthfd2,Odc1,Cdkn1a,Lrrc8c,Wdr43,Fam162a,Srm,Ppp1r14b,Sod2,Nr4a1,Pla2g4a,Gclm,Ifrd1,Tpi1,Tmem176b,Gpc1,Rbl1,Txn1,Plk2,Phlda1,Hk2,Ldha,Ptger4,Ptgs2,Thbs1,Acsl5,Dek,Plaur,Dusp1,Hsph1,Slc2a1,Timp1,Ly75,Casp3,Gsr,Ccnd1,Mdm2,Mcm10,Slc30a4,Slco3a1,Psat1,Htra1,Trip13,Timeless,Plscr1,Flnb,Procr,Hat1,Ppa1,Ell2,Dck,Gpd2,Ier3,Pfkl,Esd,Tagln,Ccl12,Nfkbia,Hivep2,Ezr,Jun,Myc,Irgm2,Cox17,Nfkbiz,Rars,Gbe1,Pttg1,Pnpt1 |
| 1.851e-13 | -29.32 | signaling | biological process | GO:0023052 | 5023 | 458 | 20694 | 1406 |
Rab21,Cx3cr1,Map2k4,Ppp1r15b,Irf1,Fchsd2,Plpp3,Cmklr1,Sgk3,Ccr3,Ptgir,Sav1,Rhoc,Ogfr,Dtx3l,Itga4,Lnpep,Fas,Prkar2b,Dnaja1,Socs7,Gng12,Cish,Sema4c,Edn1,Casp1,Ccne1,Hap1,Il18rap,Dgka,Nfkbil1,Casp4,Hivep2,Tifa,Lrp4,Ripk2,Mul1,Mvp,Nek6,Ifna5,Traf2,Prokr1,Il18,Zc3h12a,Gpr18,Nfkbib,Marco,Atf3,Rasgrp1,Rras2,Caml,Ccl12,Angpt1,Jun,Il1a,Daxx,Tnf,Plk3,Mapkbp1,Cited2,Stxbp1,Bambi,Il13ra1,Arid5b,Irs2,Jmjd6,Cd40,Mtdh,Adora2b,Ppp1r12b,Rap2c,Cd86,Spn,Pik3cd,Rapgef2,Plscr1,Pde7b,Ksr1,Traf1,Bcl9,Gna15,Klf6,Cyfip1,Ralgds,Hilpda,Lgals9,Il15ra,Cd274,Ccl22,Plcl2,Sirt1,Osm,Cav1,Cxcl11,Dbnl,Itpr1,Adrb2,Nfkbia,Batf,Ccl2,Stat5a,Map3k8,Eif2ak2,Gpr85,Pdpn,Socs1,Azi2,Tnc,Ifna2,Socs3,Rnf34,Ptk2,Nr1h3,Tle3,Prkx,Rac3,Ccl8,Pdgfrb,Fzd5,Ptpn2,Gpr84,Il15,Hcar2,Csf1,Nupr1,Gng11,S1pr2,Spen,Dgkh,Rhoq,Sipa1l1,Stat2,Fpr2,Map2k1,Dock10,Pdk3,Trim12c,Nr3c1,Bcl2l11,Bcl2a1a,Peli1,Tnfsf15,Asb13,Lif,Flt1,Rgs14,Akt3,Itga9,Tnfrsf1b,P2ry14,Rictor,Inhba,Irf7,Traf5,Ddx58,Tyk2,Rab19,Sphk1,Errfi1,Jak2,Lcp2,Tlr6,Pikfyve,Spata13,Casp8,Cdkn1a,Etv5,Ifna6,Nck1,Gpr35,Agtrap,Acvrl1,Arhgap26,Inpp5b,P2ry12,P2ry2,Mt2,Bcl2a1b,Sik3,P2ry13,Agrn,Il12b,Ifitm1,Bnip3,Cd14,Ednrb,Tnip3,Daam1,Ogfrl1,Stxbp3,Casp2,Bmp2,Nrp2,Cpeb4,Plek,Il2rg,Lox,Tnfrsf8,Saa3,Nfkb2,Acvr1b,Dusp1,G3bp2,Pmaip1,Trib3,Isg15,Il1b,Mlkl,Gpr141,Ifna1,Nfkb1,Ppp2r5a,Ppm1l,Prkce,Cdk5r1,Tlr3,Nfkbiz,Plat,Ifnar1,S100a8,Nr4a1,Acvr1,Plaur,Rgl1,Cdc42ep4,Adgrg6,Adora2a,Aim2,Ptger4,Itgb8,Irak3,Zfp36,Nod2,Flrt2,Nfkbid,Adap2,Lrp8,Homer1,Stap1,Xcr1,Stx11,Ptprj,Tlk2,Nmi,Map4k4,Gng4,Gcnt2,Cdc42ep2,Icosl,Dyrk2,Irgm2,Sesn3,Ifna4,Nos2,Cxcl9,Scn1b,Rgs1,Notch1,Rhoh,Tiparp,Irak2,Cd300lf,Itgal,Plpp1,Themis2,Tlr2,Hmox1,Clec4d,Pim1,Rnd3,Clec4e,Uaca,Adgre4,Pml,Ccr1,Zyx,Pik3r5,Col4a2,Rab20,Fzd1,Sod2,Ccl3,Ifi204,Syk,Pde3b,Stat4,Ccl4,C3,Cd74,Tlr1,Oas2,Ift22,Pde4b,Rnf31,Fpr1,Malt1,Ifnb1,Nod1,Ccl5,Cxcl2,Igf1r,Larp1,Fgr,Map3k6,Nox1,Phip,Arhgef3,Stoml1,Adgrl2,Rgs3,Cd38,Tank,Rab9,Abr,Fos,Bcl2a1d,Cd80,Atm,Acsl1,Axl,Gpsm2,Hp,Hhex,Pik3r6,Arf4,Ier3,Tnip1,Il4ra,Kremen1,Lyn,Clcf1,Ahr,Sdc1,Rab32,Ptch1,Slc39a4,Htr2b,Rims3,Pdzd11,Ezr,Dio2,Maml2,Scyl2,Ddit4,Tlr9,Apaf1,Pf4,Slc9a1,Fcgr1,Ppfia3,Cxcl1,Ccl7,Rhou,Tulp3,Phactr4,Vegfc,Mecp2,Cenpj,Iigp1,Znrf3,Olfr56,Ccl9,Htr2a,Pde5a,Myc,Fcgr4,Dcp1a,Dock4,Dennd1b,Ifih1,Pde1b,Csf3r,Csrnp1,Ccrl2,Lcn2,Kcnj2,Sema3c,Gpr68,Hck,Stat3,Src,Egr3,Ggct,Lpar1,Ikbke,Klrk1,Pdgfb,Ero1l,Ebi3,Ptafr,Cxcl10,Gnb4,Apba1,Il12rb1,Cxcl3,Trib1,Ripk3,Cysltr2,Crkl,Rin2,Stat1,Flrt3,Fcgr2b,Ift57,Myd88,Serp1,Met,Kitl,Pilra,Cacna1d,Mdfic,Cx3cl1,Ubash3b,Nlrc5,Kdr,Rcan1,Mark2,Rnd1,Il1rn,Cgas,Gdf15,Bcl6,Ppp1r15a,Calcrl,Notch2,Rab10,Tagap,Egr1,Fut8,Vcam1,Rapgef5,Sema4a,Rel,Gem,Cd34,Grk3,Cacnb3,Mt1,Plk2,Prnp,Jag1,Il6,Hif1a,Itga5,Mapkapk2,Hmga2,Dtx2,Gpr132,Mdm2,Pdgfc,Relb,Nr4a3,Ccnd1,Rhof,Ikbkg,Gja1,Itgav,Casp3 |
| 1.859e-13 | -29.31 | negative regulation of developmental process | biological process | GO:0051093 | 1065 | 137 | 20694 | 1406 |
Il15ra,Trib3,Hhex,Hmga2,Il1b,Mdm2,Mmp9,Sirt1,Kremen1,Il4ra,Lyn,Cav1,Klf7,Cdk5r1,Ahr,Pbx1,Ccnd1,Ptch1,Gja1,Itgav,Sema4a,Bmp2,Cd86,Ctsc,Lhx2,Rapgef2,Plk2,Cd38,Thbs1,Cflar,Abr,Jag1,Kdm4a,Il6,Hif1a,Casz1,Cd74,Parp3,Gdf15,Aida,Bnip3,Bcl6,Ednrb,Ifnb1,Jdp2,Zhx2,Sinhcaf,Rgcc,Srgn,Rbl1,Ankrd17,Cxcl14,Ccr1,Nampt,Pml,Cdkn1a,Katna1,Tmem176a,Pilrb1,Noct,Col4a2,Acvrl1,Tcf4,Sod2,P2ry12,Daxx,Il1a,Tnf,Ubash3b,Pde3b,Cited2,Gfi1,Akt3,Notch1,Tomm70a,Plac8,Fgl2,Il18,Zc3h12a,Trib1,Pgk1,Inhba,Vasn,Tlr2,Rap1gap2,Foxp4,Stat1,Timp1,Bcor,Jarid2,Ldlr,Map4k4,Gpr68,Sema3c,Stat3,Hlx,Mul1,Lpar1,Lrp4,Pdgfb,Spred1,Tmem178,Lif,Cxcl10,Ptk2,Dync1i2,Zeb1,Ccl9,Sav1,Clec2d,Prag1,Myc,Zfp36,Ptpn2,Nfkbid,Spry2,Tmem176b,Serpine1,Fas,Klf2,Ifrd1,Sema4c,Stap1,Cx3cr1,Tnfsf4,Pf4,Adrb2,Nfkbia,Ccl2,Irf1,Stat5a,Tspo,Socs1,Hopx,Ptger4,Tulp3,Mecp2 |
| 1.871e-13 | -29.31 | GO_REGULATION_OF_HYDROLASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_HYDROLASE_ACTIVITY | 1205 | 168 | 15632 | 1249 |
Ifi208,Tnfsf15,Pdgfb,Inpp5b,Ifit1bl2,Rgl1,Sipa1l1,Tnfsf10,Thbs1,Serpinb2,Elmod2,Tcea1,Plaur,Oas1g,Ptafr,Serpinb9,Rffl,Dennd1b,Tbc1d1,Casp3,Mdm2,Ppp6r1,Cst7,Casp1,Src,Ifi213,Birc2,Cd40,Ifi205,Timp1,Psmb9,Rgs14,P2ry12,Ahsa1,Bmp2,Nod1,Rhoc,Ripk3,Crim1,Pml,Rhoh,Psme1,Spata13,Icam1,Plscr1,Ifi203,Casp2,Rasgrp1,Sirt1,Oas1a,Birc3,Rabgef1,Psmb8,Tnfsf14,Gna15,Rgs1,Tagap,Casp7,Mefv,Adrb2,Il6,Ppp2r5a,Ccl2,Myc,Prkce,Spry2,Agrn,Bcl2l11,Ccl12,Ifit1bl1,Flt1,Dock4,Jun,Htr2a,Cdc42ep2,Angpt1,Abr,Nlrp3,Pttg1,Ccl22,Tbc1d13,Ppp2r3a,Spint2,Sh3bp4,Rapgef2,Ccl5,Psd4,Plek,Serpine1,Pdgfrb,Ppp1r15a,Tor1aip1,Kitl,Ralgds,Ppp2r2a,Htr2b,Pkp4,Cdc42ep4,Il2rg,Cycs,Stat3,Hspa2,Dock10,Prdx5,Sele,Errfi1,Arhgap26,Tnf,Bcl6,Ifi209,Oas3,Traf2,Arhgef3,Rnf34,Ccl3,Apaf1,Rgs3,Rab3ip,Asap3,Aim2,F11r,Psme2,Slpi,Cnn3,Ifi211,Rap1gap2,Egln3,Rictor,S100a8,Adap2,Mndal,Casp8,Cav1,Plekhg1,Ppp2r1b,Ccl4,Arf4,Jak2,Wdr43,Fam162a,Dennd2a,Ptgir,Mmp9,C3,Tlr9,Ptk2,Lpar1,Ifi204,Mmp14,Tor1aip2,Ift57,Psd,Rin2,Rapgef5,Eif2ak2,Trip10,Nlrc4,Ifi207,Spred1,Cdkn2d,Fas,Nck1,Cx3cl1,Irs2,Mul1,Nr1h3,Ifi214,Cyth3 |
| 1.949e-13 | -29.27 | GSE43955_10H_VS_30H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_10H_VS_30H_ACT_CD4_TCELL_UP | 187 | 48 | 15632 | 1249 |
Ptch1,Lmo4,Marco,Cav1,Eno2,Stx6,St3gal5,Flnb,Trim21,Cacnb3,Ppa1,Ets2,Dnaja1,Cpd,Peli1,Ccl2,Il6,Nr1h3,Nkiras1,Ccl22,Tlr6,Usp25,Igsf8,Ppp1r15a,Vasp,Cxcl2,Scn1b,Reps1,Kcna3,Pcgf5,Glrx,Pgk1,Plaur,Vegfc,Plat,Vcam1,Pcdh7,Hspa1a,Ifit2,P4ha2,Tnf,Ccng2,Rsad2,Il1a,Upp1,F11r,Ch25h,Stau1 |
| 1.953e-13 | -29.26 | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_DN | 174 | 46 | 15632 | 1249 |
Plekha2,Gem,Birc3,Dcun1d3,P4ha1,Eef1e1,Egln3,Rasgrp1,Rcn1,Nfil3,Cdkn1a,Cd300lf,Itgav,Srm,Gadd45g,Pcx,Myc,Prnp,Etv3,Atf3,Spred1,Pim3,Pfkfb3,Asns,Pde4b,Hk2,Sap30,Trib3,Chic2,4930453N24Rik,Smox,Smc5,Pcgf5,Ppp2r2a,Sec24a,Arid5a,Slc2a1,Tnf,Errfi1,Cish,Hif1a,Jmjd6,Socs1,Malt1,Csrnp1,Gys1 |
| 1.953e-13 | -29.26 | positive regulation of peptide secretion | biological process | GO:0002793 | 330 | 62 | 20694 | 1406 |
Il6,Lif,Hif1a,Ripk2,Tnfsf15,Casp4,Cd38,Gpr68,Cd34,Clec5a,Src,Casp1,Sec24a,Jak2,Gja1,Htr2b,Ifnar1,Tnfrsf14,Osm,Il4ra,Clec4e,Ddx58,Tlr2,Prkce,Clcf1,Frmd4a,Clec4n,Sirt1,Lgals9,Il1b,Nlrp3,Cd274,Ptger4,Vegfc,Syk,Mmp13,Cacna1d,Tnf,Aim2,Il1a,Ccl3,Adora2a,Serp1,S100a8,Ezr,Il10,Rasgrp1,Arid5a,Glrx,Tnfsf4,Nlgn2,Fgr,Ifih1,Nod2,Irs2,Hcar2,Hk1,Rgcc,Fzd5,Gsdmd,Cd14,Tlr1 |
| 2.032e-13 | -29.22 | regulation of cysteine-type endopeptidase activity | biological process | GO:2000116 | 240 | 51 | 20694 | 1406 |
Plaur,Nr4a1,Casp8,Pml,S100a8,Birc3,Tnfsf10,Psmb9,Apaf1,Ift57,Adora2a,Tnf,Aim2,Rffl,Fam162a,Rnf34,Syk,Mefv,Cst7,Malt1,Myc,Fas,Serpinb9,Nod1,Cdkn2d,Birc2,Casp1,Hspa1b,Src,Bcl2l11,Casp4,Thbs1,Ptgs2,Bcl2a1d,Cflar,Tnfsf15,Ripk2,Mul1,Il6,Nlrp3,Pmaip1,Mmp9,Sirt1,Mdm2,Tnfsf14,Cycs,Nlrc4,Jak2,Prdx5,Stat1,Uaca |
| 2.034e-13 | -29.22 | GO_CELLULAR_RESPONSE_TO_LIPID | MSigDB lists | GO_CELLULAR_RESPONSE_TO_LIPID | 430 | 81 | 15632 | 1249 |
Cd180,Hif1a,Icam1,Nfkbil1,Daxx,Tnfaip3,Hck,Cd14,Cd40,Tnf,Axl,Src,Mdm2,Errfi1,Acvr1,Tnc,Nr3c1,Pim1,Il18,Serpinb9,Ptafr,Il12b,Cxcl10,Nr4a3,Ptger4,Zc3h12a,Ripk2,Cmpk2,Il1b,Irak2,Cd86,Serpine1,Pde4b,Ccl5,Csf3,Inhba,Fzd1,Nr1h3,Nlrp3,Fas,Lrp8,Ahr,Plau,Il15,Cd80,Tspo,Dnaja1,Cx3cr1,Nfkbia,Nr4a1,Ass1,Ccl12,Ifnb1,Edn1,Il6,Prkce,Stap1,Lpar1,Tnip3,Lyn,Tlr2,Tnfsf4,Mtdh,Hmgcs1,Pmepa1,Gfi1,Jak2,Il10,Pid1,Irf8,Nos2,P2ry2,Ptch1,Pdk3,Nfkb1,Ccne1,Rnf14,Tnfrsf1b,Ednrb,Med13,Nfkbib |
| 2.072e-13 | -29.21 | GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP | 149 | 42 | 15632 | 1249 |
Arl5b,Btg2,Maff,Nfkbid,Gch1,Ifit1bl2,Rel,Cd274,Gca,Dnajb2,Tagap,Dusp16,Ell2,Zc3h12a,Kdm6b,Cxcl10,Nr4a3,Adrb2,Katna1,Dusp8,Tor1aip2,Psd,Tra2a,Sbds,Tagln,Ifit1bl1,Nr4a1,Homer1,Fbrsl1,Slc25a25,Relb,Zc3hav1,Tnfaip3,Egr1,Mthfr,Csrnp1,Mxd1,Plk3,Atf3,Traf1,Rnd1,Fam133b |
| 2.148e-13 | -29.17 | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN | 168 | 45 | 15632 | 1249 |
Flnb,Slamf9,Trem1,Sema4c,Tlr2,Pla2g4a,Slc44a1,Fam43a,Fos,Ets2,Pfkfb3,Aff1,Olr1,Tpi1,Gbe1,Phlda1,Vasp,Cxcl2,AA467197,Ccl5,Tuba4a,Lcp2,Klf2,Il1rn,Cxcl1,Cldnd1,Sec24a,Pgk1,Il1b,Ldha,Zc3h12a,Ak4,Slc43a3,Ptgs2,Osgin2,Gpr84,Errfi1,Mafk,Tnf,Slc25a37,Timp1,Plk3,Tab2,Il1a,Sell |
| 2.184e-13 | -29.15 | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | MSigDB lists | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | 131 | 39 | 15632 | 1249 |
Maff,Isg20,Zeb1,Ddit4,Phlda1,Asns,Ppp1r15a,Klf2,Psat1,Plek,Dnajb2,Glrx,Gtpbp2,Asf1a,Trib3,Trib1,Dnajb4,Mafg,Arid5b,Cd55,Fndc3a,Hmox1,Dusp5,Ifrd1,Ccng2,Gclm,Sat1,Rab9,Jun,Morc3,Klf6,P4ha2,Dusp1,Sqstm1,Slc7a11,Il15,Rnd3,Atf3,Palld |
| 2.195e-13 | -29.15 | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN | 181 | 47 | 15632 | 1249 |
Ppp2r5a,Igsf6,Ctsc,Kcnj2,Sod2,Bcl2a1b,Ifit1bl1,Pilra,Fas,Slpi,Bcorl1,Casp4,Ifit3,Tnfrsf1b,S100a8,Nfil3,Trem1,Cflar,Ier3,Acsl1,Ifit3b,Trib1,Mppe1,Bcl2a1d,Cebpd,Fgl2,P2ry13,Cd302,Csf3r,Slc16a3,Hck,Hlx,Vasp,Bst1,Nmi,Ifit1bl2,Fcgr4,Slc31a2,Txn1,Nampt,Plek,Gca,Tnfsf10,Bcl2a1a,Fpr1,Ptgs2,Xkr8 |
| 2.236e-13 | -29.13 | CUI_TCF21_TARGETS_2_DN | MSigDB lists | CUI_TCF21_TARGETS_2_DN | 744 | 118 | 15632 | 1249 |
Cd38,Zfp319,Tnfaip3,Sgk3,Prdm1,Arhgap26,Rbpms,Cers6,Itgb8,Mtus1,Homer1,Cxcl1,Kitl,Plat,Rcan1,Usp42,Il2rg,Arid5b,Spire1,Tlr3,Atp10a,Vasn,Parp12,Wdfy1,Stxbp3,Hopx,Vps54,Golga3,Pde4b,Cdyl,Dusp6,Myadm,Enpp4,Slfn5,Zc3hav1,Gpc1,Slc48a1,Pgm1,Usp25,Palld,Ifrd1,Rin2,Optn,Phlpp1,Parp14,Tor1aip2,Lrch1,Cited2,Klf3,Rapgef5,H3f3b,Frmd6,Nfil3,Rbms1,Dnajb4,Itga9,Cpeb4,Uaca,Mmd,Rictor,Med13,Atxn7l1,Plekhg1,Plod2,Gem,Ednrb,Crim1,Myo10,Calcrl,St3gal6,Hhex,Itga4,Hlx,Malt1,Lztfl1,Tbc1d1,Hspa1a,Fmnl2,Thbs1,Nsmaf,Ptprj,Cd55,Ptger4,Fndc3a,Tmem26,Rilpl1,Pdgfb,Ppm1k,Myo1b,Arid4a,Jarid2,Rras2,Pfkfb3,Sdc2,Abcb1a,Bbx,Dock4,Tiparp,Nfkbia,Flt1,Hivep2,Fam43a,Armc8,Sh3bgrl2,Cflar,Gpd2,Ifi35,Endod1,Stat1,Ell2,Tmod3,Il13ra1,Ccrl2,Plscr1,Htra1,Dach1,Clic5,Lnpep |
| 2.272e-13 | -29.11 | MODULE_76 | MSigDB lists | MODULE_76 | 76 | 29 | 15632 | 1249 |
Fos,Bcl6,Tpst1,Cd40,Aoah,Ccl12,Cxcl14,Ccl2,Ly75,Il1a,Fpr2,Cx3cl1,Cd14,Ccr1,Nfkb1,Pla2g7,Adora2a,Nmi,Tlr1,Ptgs2,Cxcl10,Tlr2,Ptafr,Fpr1,Tlr3,C3,Il1b,Cxcl1,Ccl4 |
| 2.293e-13 | -29.10 | MODULE_292 | MSigDB lists | MODULE_292 | 108 | 35 | 15632 | 1249 |
H2-Aa,Plscr1,Csf3,Oas1a,Pou2f2,Kctd12,Dgka,Ifit1bl2,Cd86,Samsn1,Vcam1,Thbs1,Tnfsf10,Adam19,Trem1,Ifi35,H2-Ab1,Oas1g,Cd200,Fpr1,Peli1,Ifi44,Sdc2,Mecp2,Cebpd,Nlrc5,Ifit1bl1,Sp140,Oas3,Cd14,Hvcn1,Gbp2,Cd74,Isg15,Sell |
| 2.419e-13 | -29.05 | GSE7852_TREG_VS_TCONV_LN_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_LN_UP | 188 | 48 | 15632 | 1249 |
Ahr,Ppm1l,Ubash3b,Plagl1,Nfkbiz,Dusp4,Phlpp1,Irf4,Itgav,Frmd6,Rgs1,Odc1,Ebi3,Endod1,Ccrl2,Trim14,Casp4,Rel,Zc3h12c,Irf8,Tnfrsf1b,Gbp2,Mdfic,Nod1,Cd83,Rnf135,Gbp3,Mxd1,Gpr68,Fgl2,Cish,Slc2a1,Swap70,Cst7,Axl,Klf6,Glrx,Osbpl3,Map3k8,Hk2,Il12rb1,Vps54,Cd86,Lad1,Hopx,Cd274,Samsn1,Myadm |
| 2.621e-13 | -28.97 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN | 195 | 49 | 15632 | 1249 |
Igsf6,Slc15a3,Rhoq,Kcnj2,Cebpd,Vcan,Fgl2,Rin2,Ogfrl1,Syk,Rab32,Rhbdf2,Csf3r,Cyfip1,Dse,Cd14,Pilra,Hck,Hk3,Hlx,Nlrp3,Dmxl2,Cd74,Slc2a6,Kctd12,Wars,Dusp6,Ccr1,Slc31a2,Fcgr4,Snx10,Adap2,Irf8,Marco,Cd86,Gca,Tnfaip2,Clic4,Il1rn,Tfec,Plaur,Il13ra1,Hmox1,Tlr2,Lyn,Fpr1,Acsl1,Slc43a3,Tgfbi |
| 2.658e-13 | -28.96 | negative regulation of lymphocyte activation | biological process | GO:0051250 | 152 | 39 | 20694 | 1406 |
Nfkbid,Tarm1,Ifnb1,Il4ra,Lyn,Tnfaip3,Tnfrsf14,Fas,Casp3,Cd74,Axl,Parp3,Lgals9,Cd274,Bcl6,Pde5a,Fgl2,Samsn1,Ptpn2,Zc3h12a,Hlx,Adora2a,Slfn1,Socs1,Cd80,H2-Aa,Atm,Arg2,Il10,Fcgr2b,Tnfsf4,Sdc4,Cd86,Spn,Prdm1,Irf1,Prnp,H2-Ab1,Peli1 |
| 2.675e-13 | -28.95 | GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | MSigDB lists | GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | 92 | 32 | 15632 | 1249 |
Cd86,Cd274,Il10,Rasgrp1,Zfp36,Tlr1,Ptafr,Il12b,Tlr2,Tlr9,Tlr3,Ptger4,Ripk2,Zc3h12a,Pf4,Jak2,Thbs1,Spn,Axl,Ccl12,Nod2,Errfi1,Nfkbil1,Mapkapk2,Irak3,Angpt1,Tnfaip3,Nod1,Cd34,Cd14,Tnfrsf8,Tspo |
| 2.735e-13 | -28.93 | GSE3982_MAST_CELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_NEUTROPHIL_DN | 182 | 47 | 15632 | 1249 |
Mmp25,Acsl1,Map2k4,Ifi204,Pim2,Gsta3,Mndal,Ikbkg,Syne2,Ifi203,Zeb1,Ifi211,Isg20,Ifi214,Kat2b,Tlr6,Cdkn2d,Vcpip1,Ifi207,Cdc42ep2,Htr2a,Pfkfb3,Herc3,Cx3cr1,Cxcl14,Ptafr,Pim1,Kcna3,Xkr8,Glrx,Slc12a9,Junb,Slc31a2,Vasp,Ifi208,Ifih1,Tnfaip3,Apaf1,Cd14,Ifi205,Bcl6,Ifi209,Psmb9,Klhl25,Ifi213,Slc15a3,Stat3 |
| 2.958e-13 | -28.85 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_UP | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_UP | 163 | 44 | 15632 | 1249 |
Cd38,Tnfaip3,Plk3,Lrp8,Icam1,Fpr2,Trim13,Traf1,Sphk1,Itgb8,Rai14,Gpr68,Gsr,Psma6,Slc7a11,Sod2,N4bp1,Tpst1,Acsl5,Irak2,Trem1,Plaur,Il1b,Ebi3,Zc3h12a,Rcn1,Clec5a,Tnip3,Odc1,Ak4,Acvr1b,Slc43a3,Srxn1,Procr,Tmeff1,Pdlim7,Slc7a5,Pdss1,Ampd3,Cxcl2,AA467197,Met,Txn1,Rrs1 |
| 2.994e-13 | -28.84 | leukocyte migration | biological process | GO:0050900 | 196 | 45 | 20694 | 1406 |
Flt1,Ccl4,Cxcl10,Mcoln2,Pdgfb,Syk,Cxcl9,Tnf,Cx3cl1,Ccl7,Ccl3,Cxcl1,Gpr35,Ccl2,Trem1,Slamf8,Spn,Cd34,Pf4,Ccl12,Cx3cr1,S100a8,Ccr1,Csf3r,Vcam1,Crkl,Cxcl2,Ccl5,Cxcl11,Icam1,Sell,Sbds,Cxcl3,Ednrb,Itga9,Itga4,Ccl8,Pde4b,Ccl22,Ccl9,Il1rn,Il1b,Ch25h,Ccr3,Sele |
| 3.125e-13 | -28.79 | regulation of endopeptidase activity | biological process | GO:0052548 | 368 | 66 | 20694 | 1406 |
Birc2,Serpinb2,Fas,Serpinb9,Cdkn2d,Nod1,Serpine1,Malt1,Myc,Mefv,C3,Cst7,Rnf34,Syk,Adora2a,Serpina3g,Tnf,Aim2,Rffl,Fam162a,Tnfsf10,Psmb9,Apaf1,Ift57,Hdac1,Plaur,Nr4a1,Casp8,Pml,Birc3,S100a8,Psmb8,Nlrc4,Prdx5,Jak2,Timp1,Stat1,Uaca,Tnfsf14,Lyn,Cycs,Psme1,Mmp9,Sirt1,Mdm2,Nlrp3,Serpinb9b,Pmaip1,Psme2,Slpi,Il6,Serpinb6b,Serpina3f,Ptgs2,Tnfsf15,Cflar,Bcl2a1d,Mul1,Ripk2,Src,Hspa1b,Bcl2l11,Stat3,Casp4,Thbs1,Casp1 |
| 3.151e-13 | -28.79 | negative regulation of cell adhesion | biological process | GO:0007162 | 283 | 56 | 20694 | 1406 |
Cd86,Bmp2,Ass1,Map2k1,Thbs1,Spn,Prnp,H2-Ab1,Peli1,Src,Gcnt2,Hlx,Jag1,Cd80,Dusp1,Arg2,Lgals9,Notch1,Cd274,Swap70,Zc3h12a,Fgl2,Tnfrsf14,Tnfaip3,Tarm1,Il4ra,Myadm,Casp3,Jak2,Spint2,Il10,Sdc4,Tnfsf4,Adrb2,Acvrl1,Angpt1,Irf1,Socs1,Slfn1,Adora2a,Ubash3b,H2-Aa,Pde3b,Tnc,Cd74,Mmp14,Ptk2,Il1rn,Rnd1,Bcl6,Pde5a,Ptpn2,Serpine1,Ifnb1,Nfkbid,Rgcc |
| 3.161e-13 | -28.78 | KRIEG_HYPOXIA_NOT_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_NOT_VIA_KDM3A | 651 | 107 | 15632 | 1249 |
Rnf24,Cp,Ccng2,Mafk,Klf6,Ifit2,P4ha2,Mtus1,Arid5a,Gys1,Sav1,Tnfaip3,Pdgfc,Slc39a13,Tab2,Sap30,Ddit4,Fzd1,Myadm,Ccr1,Map2k1,Pgk1,Pcgf5,Crkl,Spire1,Trib3,Bnip3,Rin2,Sod2,Ppp1r14b,Slc16a1,Fbrsl1,Tpi1,Nek6,Fas,Irs2,Cyth3,Kat2b,Pgm1,Sdc1,Isg20,Hk1,Plod2,Znrf1,Fscn1,Nfil3,Pmepa1,Wdr43,Fam162a,H3f3b,Dram1,Rab20,Rab9,Nr3c1,Ccnd1,Kdm5b,Ifnar1,Dusp1,Eno1,Slc2a1,Swap70,Bfar,Sphk1,Jmjd6,Icam1,Antxr1,Slc7a5,Maff,Hk2,Tuba4a,Mthfd1l,Slc31a2,Rnaset2a,Zhx2,Ldha,Smox,Usp31,Lox,Slc43a3,Ak4,Myc,Il6,Triobp,Nfkbia,Hivep2,Rhof,Zyx,Jun,Tiparp,Gclc,Rras2,Pfkfb3,Gbe1,Plagl1,Trip13,Zc3h7a,Slc39a14,P4ha1,Eno2,Abtb2,Rabgef1,Ogfr,Tnip1,Rnaset2b,Ell2,Dyrk2,Ier3 |
| 3.195e-13 | -28.77 | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_UP | MSigDB lists | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_UP | 157 | 43 | 15632 | 1249 |
Agtrap,Psme1,Mvp,Cd14,Acpp,Traf2,Cst7,Lipe,B3gnt5,Ptafr,Ak4,Slamf8,Smox,Rcl1,Clic4,Pdgfrb,Cd86,Stx11,Rapgef2,Antxr1,Tmtc2,Palld,Tmem176b,Foxp4,Gpr18,Vcan,Kremen1,Prokr1,Uaca,Casp7,Igf1r,Jak2,Hdc,Irf8,Etv6,Dcp1a,Stat4,Ppp4r2,Med13,Flnb,Procr,Ksr1,Csf1 |
| 3.209e-13 | -28.77 | GAURNIER_PSMD4_TARGETS | MSigDB lists | GAURNIER_PSMD4_TARGETS | 67 | 27 | 15632 | 1249 |
Ccl5,Nfkb1,Ccr1,H2-Eb1,Il10,Cd86,H2-Aa,Cxcl2,Il12rb1,C3,Il13ra1,H2-Ab1,Cxcl10,Il12b,Il2rg,Nfkb2,Cxcl1,Ccl12,Tnf,H2-Q4,H2-Q6,Ccl2,Il6,Ccr3,H2-Q7,Il1a,Relb |
| 3.230e-13 | -28.76 | GO_REGULATION_OF_LEUKOCYTE_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_LEUKOCYTE_PROLIFERATION | 196 | 49 | 15632 | 1249 |
Bcl6,Cd40,H2-Q6,Pnp2,Casp3,H2-Q7,Prdm1,Cd74,Ccdc88b,Tnfaip3,Cd38,Ripk3,Ccl5,H2-Eb1,Cd274,Cd86,Icosl,Bst1,Il12rb1,Ripk2,Cd55,Il12b,Il18,Kitl,Vcam1,Il1b,Syk,H2-Q4,Spn,Peli1,Il6,Pde5a,Nck1,Irs2,Prnp,Cd80,Il27,Il15,Ahr,Tnfrsf14,Atm,Il10,Csf1,Tnfsf4,Ebi3,Lyn,Irf1,Clcf1,Cdkn1a |
| 3.261e-13 | -28.75 | response to nitrogen compound | biological process | GO:1901698 | 924 | 123 | 20694 | 1406 |
Casp7,Zeb1,Ptk2,Ptpn2,Htr2a,Irak3,Myc,Itga4,Nod2,Dnajb2,Rhoq,Homer1,Ifih1,Socs7,Pde1b,Tnfsf4,Nr4a1,Ezr,Irf1,Adrb2,Tlr9,Nfkbia,Slc9a1,Hdac1,Adora2a,Serpina3g,Socs1,Stat5a,Ifna2,Atp2b4,Mecp2,Notch1,Nlrp3,Zc3hav1,Akt3,Il18,Rnf139,Tlr2,Ddx58,Tnfaip3,Stat1,Tlr6,Jak2,Crkl,Ldlr,Casp1,Stat2,Fpr2,Stat3,Src,Peli1,Casp4,Serpina3f,Ifna4,Sesn3,Mul1,Ripk2,Ifna5,Traf2,Cgas,Junb,Ednrb,Actb,Pde4b,Icam1,Rab10,Egr1,Irs2,Kat2b,Ifnb1,Nod1,Hmgcs1,Tmem67,Vcam1,Phip,Stxbp3,Igf1r,Larp1,Fcgr2b,Myd88,Agtrap,Ifna6,Daxx,Tnf,P2ry12,Jun,Egr2,Pde3b,Syk,Cacybp,Sh3bp4,Stat4,Il1b,Trib3,Trim13,Sirt1,Mmp9,Pdgfc,Ifna1,Mdm2,Nr4a3,Cdk5r1,Prkce,Ccnd1,Ahr,Nfkb1,Cav1,Sell,Itpr1,Htr2b,Itgav,Casp3,Tlr3,Ppp2r2a,Nmral1,Prnp,Thbs1,Timeless,Cpeb4,Rapgef2,Jag1,Cflar,Cyfip1 |
| 3.365e-13 | -28.72 | cell communication | biological process | GO:0007154 | 5148 | 466 | 20694 | 1406 |
Hmga2,Dtx2,Mapkapk2,Pdgfc,Gpr132,Mdm2,Nr4a3,Ccnd1,Relb,Ikbkg,Rhof,Gja1,Itgav,Casp3,Gem,Sema4a,Rel,Prnp,Cd34,Grk3,Cacnb3,Mt1,Plk2,Jag1,Itga5,Hif1a,Il6,Rnd1,Cgas,Il1rn,Mark2,Rcan1,Ppp1r15a,Gdf15,Bcl6,Rab10,Tagap,Egr1,Notch2,Calcrl,Vcam1,Rapgef5,Fut8,Fcgr2b,Serp1,Myd88,Met,Ift57,Mdfic,Cx3cl1,Kitl,Pilra,Cacna1d,Kdr,Ubash3b,Nlrc5,Gnb4,Apba1,Ripk3,Cysltr2,Il12rb1,Cxcl3,Trib1,Stat1,Flrt3,Crkl,Rin2,Lcn2,Hck,Stat3,Src,Egr3,Ggct,Gpr68,Sema3c,Ikbke,Lpar1,Ptafr,Cxcl10,Pdgfb,Klrk1,Ebi3,Ero1l,Olfr56,Ccl9,Dcp1a,Fcgr4,Htr2a,Myc,Pde5a,Dock4,Dennd1b,Csf3r,Ccrl2,Csrnp1,Ifih1,Pde1b,Scyl2,Ddit4,Ezr,Maml2,Dio2,Ppfia3,Tlr9,Pf4,Apaf1,Slc9a1,Fcgr1,Ccl7,Rhou,Cxcl1,Cenpj,Iigp1,Znrf3,Phactr4,Vegfc,Tulp3,Mecp2,Hhex,Pik3r6,Axl,Gpsm2,Hp,Ier3,Arf4,Clcf1,Sdc1,Ahr,Tnip1,Il4ra,Kremen1,Lyn,Htr2b,Slc39a4,Ptch1,Rims3,Pdzd11,Rab32,Rgs3,Arhgef3,Stoml1,Adgrl2,Tank,Rab9,Cd38,Abr,Fos,Bcl2a1d,Acsl1,Higd1a,Cd80,Atm,Tlr1,C3,Cd74,Fpr1,Gsdmd,Malt1,Ift22,Oas2,Rnf31,Pde4b,Ccl5,Cxcl2,Ifnb1,Nod1,Phip,Nox1,Igf1r,Larp1,Fgr,Map3k6,Pml,Ccr1,Zyx,Col4a2,Rab20,Pik3r5,Ccl3,Ifi204,Fzd1,Sod2,Ccl4,Syk,Pde3b,Stat4,Notch1,Rhoh,Rgs1,Itgal,Tiparp,Cd300lf,Irak2,Tlr2,Clec4d,Hmox1,Pim1,Rnd3,Clec4e,Plpp1,Themis2,Adgre4,Uaca,Stx11,Ptprj,Tlk2,Nmi,Xcr1,Gcnt2,Gng4,Icosl,Cdc42ep2,Dyrk2,Asns,Map4k4,Wdr59,Nos2,Irgm2,Sesn3,Ifna4,Cxcl9,Scn1b,Itgb8,Zfp36,Irak3,Lrp8,Nod2,Flrt2,Nfkbid,Adap2,Homer1,Stap1,Nr4a1,Acvr1,Plaur,S100a8,Cdc42ep4,Adgrg6,Rgl1,Adora2a,Aim2,Ptger4,Isg15,Il1b,Pmaip1,Trib3,Gpr141,Ifna1,Mlkl,Cdk5r1,Prkce,Nfkb1,Ppm1l,Ppp2r5a,Ifnar1,Tlr3,Nfkbiz,Plat,Bmp2,Casp2,Plek,Nmral1,Nrp2,Cpeb4,Lox,Tnfrsf8,Saa3,Il2rg,Acvr1b,Dusp1,G3bp2,Nfkb2,Il12b,Agrn,P2ry13,Cd14,Ednrb,Ifitm1,Bnip3,Tnip3,Stxbp3,Daam1,Ogfrl1,Etv5,Pikfyve,Spata13,Casp8,Cdkn1a,Acvrl1,Agtrap,Gpr35,Ifna6,Nck1,P2ry2,Mt2,Arhgap26,Inpp5b,P2ry12,Bcl2a1b,Sik3,Akt3,Rgs14,Itga9,Tnfrsf1b,P2ry14,Traf5,Ddx58,Tyk2,Rictor,Inhba,Irf7,Errfi1,Jak2,Lcp2,Tlr6,Rab19,Sphk1,Map2k1,Dock10,Trim12c,Pdk3,Stat2,Fpr2,Bcl2l11,Bcl2a1a,Peli1,Nr3c1,Tnfsf15,Asb13,Flt1,Lif,Nr1h3,Tle3,Rac3,Prkx,Ptk2,Pdgfrb,Ptpn2,Fzd5,Ccl8,Il15,Hcar2,Nupr1,Csf1,Gng11,Gpr84,Rhoq,Sipa1l1,S1pr2,Spen,Dgkh,Ccl2,Batf,Adrb2,Nfkbia,Gpr85,Eif2ak2,Pdpn,Socs1,Stat5a,Map3k8,Socs3,Tnc,Ifna2,Rnf34,Azi2,Cd274,Lgals9,Il15ra,Slc2a1,Sirt1,Mmp9,Ccl22,Plcl2,Cxcl11,Osm,Cav1,Itpr1,Dbnl,Ppp1r12b,Rap2c,Cd86,Adora2b,Plscr1,Ldha,Spn,Pik3cd,Rapgef2,Gna15,Ksr1,Pde7b,Traf1,Bcl9,Hilpda,Ralgds,Klf6,Cyfip1,Il13ra1,Arid5b,Irs2,Jmjd6,Uchl1,Cd40,Mtdh,Rasgrp1,Rras2,Caml,Ccl12,Atf3,Angpt1,Il1a,Daxx,Tnf,Plk3,Mapkbp1,Jun,Stxbp1,Bambi,Cited2,Prokr1,Il18,Zc3h12a,Gpr18,Marco,Nfkbib,Il18rap,Dgka,Casp1,Ccne1,Hap1,Hivep2,Nfkbil1,Casp4,Mvp,Tifa,Lrp4,Mul1,Ripk2,Ifna5,Traf2,Nek6,Ptgir,Ccr3,Rhoc,Sav1,Ogfr,Sgk3,Lnpep,Dtx3l,Itga4,Fas,Cish,Sema4c,Edn1,Prkar2b,Dnaja1,Socs7,Gng12,Map2k4,Ppp1r15b,Rab21,Cx3cr1,Irf1,Fchsd2,Cmklr1,Plpp3 |
| 3.373e-13 | -28.72 | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | MSigDB lists | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | 72 | 28 | 15632 | 1249 |
S100a8,Ifit1bl2,Rnaset2a,Ifit3,Asns,Irf7,Pdgfrb,Procr,Slpi,Htra1,Mmp13,Pla2g7,Inhba,Stat1,Mthfd2,Ifit3b,Rnaset2b,Ifit1bl1,Ccl12,Srm,Tnc,Phgdh,Sdc2,Sdc1,Hif1a,Upp1,Gbp3,Isg15 |
| 3.396e-13 | -28.71 | BASAKI_YBX1_TARGETS_DN | MSigDB lists | BASAKI_YBX1_TARGETS_DN | 340 | 69 | 15632 | 1249 |
Sat1,Pnp2,Cers6,Ifi213,Parp8,Ifi205,Ifi209,Cd302,Etv5,Rab3ip,Marcksl1,Ier2,St3gal6,Ddit4,Stxbp3,Antxr1,Ifi208,Phlda1,Maff,Hk2,Junb,Dusp6,Gdf15,Rnaset2a,Tnfsf10,Glrx,Pgk1,Cd55,Dusp5,Ak4,Spry2,Slc44a1,Bbx,Fam43a,Flrt3,Slc7a11,Ass1,Fos,Casz1,Pfkfb3,Ifi207,Nfkbiz,Egr1,Trim13,Xrn1,Gbe1,Dmxl2,Slc30a1,Papss2,Ifi214,Ifi211,Isg20,Slc9a1,Htra1,Slpi,Rictor,Ifi203,Met,Atm,Pdk3,P4ha1,Plod2,Lcn2,Mndal,H3f3b,Rnaset2b,Fam162a,Mtdh,Ifi204 |
| 3.401e-13 | -28.71 | GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | MSigDB lists | GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | 183 | 47 | 15632 | 1249 |
Ppp1r14b,Ets2,D16Ertd472e,Rai14,Egr1,Pgs1,Ciita,Klf7,Rel,Pstpip2,Cnn3,Ppa1,Max,Tlr2,Odc1,Jak2,Hsd17b7,Abcc1,Wdr43,Stat5a,Ehd1,Hsph1,Rbbp8,Cd40,Hdac1,Mcoln2,Socs1,Sphk1,Sla,Myd88,Traf5,Gnb4,Dusp6,Slc4a7,Rgl1,Pdlim7,Phlda1,Inpp5b,Dgka,Nfkbid,Larp1,Gpr85,Spata5l1,Slamf8,Cmklr1,Il1b,Rcl1 |
| 3.402e-13 | -28.71 | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_6H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_6H_UP | 170 | 45 | 15632 | 1249 |
N4bp1,Itgb8,Cish,Mxd1,Socs1,Cd14,Crlf3,Hck,Plagl2,Nampt,Plk2,Samsn1,Ddit4,Bst1,Car13,Traf3ip2,Zc3h12a,Fpr1,Serpinb9,Thbs1,Ptges,Il1b,Sod2,Plac8,Trip10,Tet2,Fcgr2b,Cpd,Nod2,Nfkbiz,Trim13,Fpr2,Etv3,Pfkfb3,Tnfrsf1b,S100a8,P2ry2,Plscr1,Ksr1,Socs3,Sema4c,Lyn,Ier3,Tnip3,Lrrc25 |
| 3.405e-13 | -28.71 | GO_POSITIVE_REGULATION_OF_HEMOPOIESIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_HEMOPOIESIS | 151 | 42 | 15632 | 1249 |
Pf4,Il1b,Hcls1,Kitl,Acvr1b,Trib1,Il12b,Tnfsf4,Egr3,Ripk2,Jag1,Csf3,Il12rb1,Inhba,Rasgrp1,Csf1,Cd86,Pik3r6,Casp8,Ccr1,Ccl5,Il15,Cd83,Cd80,Cd74,Hif1a,Il4ra,Nlrp3,Isg15,Prdm1,Hlx,Lif,Ap3b1,Gpr68,Il6,Pnp2,Mmp14,Fos,Jun,Tnf,Axl,Syk |
| 3.421e-13 | -28.70 | DUTTA_APOPTOSIS_VIA_NFKB | MSigDB lists | DUTTA_APOPTOSIS_VIA_NFKB | 33 | 19 | 15632 | 1249 |
Cd274,Traf2,Casp8,Birc2,Gadd45b,Tnf,Birc3,Bcl2a1b,Sod2,Mdm2,Bcl2a1d,Bnip3,Traf1,Ier3,Fas,Tnfaip3,Cflar,Bcl2a1a,Tnfsf10 |
| 3.496e-13 | -28.68 | endomembrane system | cellular component | GO:0012505 | 3743 | 359 | 20747 | 1409 |
Cav1,Nod2,Atp13a1,Mmd,Irgm1,Rsad2,Rab21,Gpr85,Dock4,Lnpk,Trim13,Pgap2,Plekhf2,Nck1,Reps1,Rab10,St3gal3,Cd274,Tlr9,Adora2a,Plpp3,Ezr,Prnp,Ust,Spire1,Sgms2,Fam241a,Tmtc2,Slc31a1,Rab9,Tlr1,Bcl9,Ktn1,Ksr1,Arl5c,Cd74,Slamf7,Rcn1,H2-Q4,Mppe1,Gm4951,Slc30a1,Pnpt1,Lap3,Tmem178,Itga5,Cst7,Trim36,Gja1,Naa25,Minpp1,Micall2,Mitd1,Fzd5,Vcam1,Cacybp,Bcl6,Kcnj2,Tapbp,Serp1,Dusp2,Gsap,Tor3a,St3gal1,Ehd1,Ap3m2,Rabgef1,Clcn5,Anp32a,Kdr,Irgm2,Dbnl,Carmil1,Whamm,Mmp14,Nfkbie,Ptch1,Sec24b,Lyn,Grina,Rnaset2b,Rasgrp1,Mcoln2,Hmox1,Stx6,Phf11d,Gpc1,Flrt2,Pla2g4a,Ext1,Ap3b1,Hk2,Sgk3,Rapgef2,Apba1,Tap1,Adrb2,Tent4a,Prpf38a,Uaca,Plagl1,Caml,Flt1,Wdfy1,Rab11fip1,Dgkh,B4galt4,Mtus1,Dtx2,Vps54,Chic2,Fam20c,Phf11c,Slc29a3,Gdf15,Znrf1,Dync1h1,Parp11,Slc16a3,Cd14,Myo1b,Tlr3,Arf4,Pde4b,Keap1,St3gal5,Src,Sh3bgrl2,Syne2,Sirt1,Nlrp3,Bnip3,Dnaja1,Flrt3,Ifi47,Rtn2,Nt5c3,Ppp1r15a,Dnase1l3,Chmp4b,Trib3,Dmxl2,Rhou,Degs2,Marf1,Rhbdf2,Plod2,Vcpip1,F830016B08Rik,Ptpn2,Lipg,Rab32,Gramd1a,Myc,Plod3,Stxbp3,Piezo1,Thbs1,Mosmo,Itpr1,Plat,Pgs1,Rnd3,Ift57,Stoml1,Cd38,Snx10,Ppfia3,Dst,Ociad1,Rap2c,Traf2,Ric1,Sema4c,F10,P2ry13,Stau1,Il1b,Lpar1,Ccl2,Hsd17b7,Fcgr2b,Aftph,Ifit2,Pde3b,Asah2,P2ry2,Ppp1r15b,Slc48a1,Fndc3a,Ccnd2,Rnaset2a,Slc31a2,Hilpda,Rnf24,Gcnt2,Edn1,St3gal6,Lpcat2,Slc30a4,Pigv,Plaat3,Smox,Dpy19l1,Ass1,Slc7a11,Notch1,Abcc4,Uchl1,Tlr6,Plscr1,Cpeb4,Stxbp1,Tap2,H2-Q6,Slc39a4,Gm4841,Psd,Dennd6b,9930111J21Rik1,Pf4,Calcrl,Clic5,Tmem67,Iigp1,Cers6,Serpinb9,Gbp2,H2-Q7,Pikfyve,Vrk2,Sqstm1,Slc9a1,Ptgs2,Ptger4,Hp,Trip10,Usp25,Ero1l,Dnajb2,Rffl,Rnf145,Ednrb,Srgn,Tor1aip2,Hsd17b12,Fchsd2,Rnf139,Tlr2,Sphk1,Golga3,Atp11a,Serpine1,Chst11,Rac3,Rtn1,Mgat1,Igtp,Samd9l,Gbp2b,Tor1aip1,Mtdh,Atp11b,Sec24a,Adam19,Cd164,Phlpp1,Ranbp2,Pmepa1,Mmp13,Lrrc8c,Hck,Tgfbi,Acpp,Gbgt1,Atp10a,Inpp5b,Kif3c,Tnf,Fut8,Acsl1,Rrs1,1600014C10Rik,Gch1,Marcksl1,Casp4,Trim12c,Nxf1,Dtx3l,Prkce,Gbp3,Rrbp1,H2-Eb1,Ch25h,Nox1,Shisa3,Nr4a1,Ctsc,Mx1,Bfar,Ifnar1,Fcho2,Phf11a,H2-Ab1,Phf11b,Ccdc88b,Rab20,Cpd,Ldlr,P4ha2,Ankrd17,Gm12185,Cop1,Ccr3,Sele,Ptges,Gm5431,Dse,Sh3bp4,Fos,Stx11,Arl5b,Tspo,Pml,Cxcl14,Agtrap,Sla,Tpst1,Extl2,Osbpl3,Fas,Rap1gap2,Tgtp2,Hap1,Cept1,Ifitm1,Treml4,Arrdc4,Snx2,B3gnt5,Plk3,Slc39a13,Rab3ip,Zc3hav1,Glipr2,Dhrs9,Tgtp1,Optn,Tapbpl,Pdgfrb,Zc3h12a,Acsl5,P4ha1,Scyl2,Slc37a3,Ahsa1,Map2k1,Rab19,Rnf19b |
| 3.566e-13 | -28.66 | chemotaxis | biological process | GO:0006935 | 496 | 80 | 20694 | 1406 |
Ccr3,Agrn,Ch25h,Il1rn,Ccl9,Fpr1,Ednrb,Pdgfrb,Ccl8,Pde4b,Dock4,Ccl5,Cxcl2,Flrt2,Sema4c,Vcam1,Ext1,Ntng2,Csf3r,Ccrl2,Cxcl14,Abcc1,Nr4a1,Ccl12,Ccr1,S100a8,Cx3cr1,Ccl2,Angpt1,Met,Gpr35,Pf4,Evl,Slamf8,Ccl3,Ccl7,Cx3cl1,Cxcl1,Kif5c,Ccl4,Cmklr1,Egr2,Syk,Vegfc,Il1b,Lgals9,Palld,Itga9,Ccl22,Nr4a3,Cdk5r1,Cxcl11,Cxcl3,Klf7,Sbds,Itgav,Ptch1,Flrt3,Crkl,Ptprj,Xcr1,Sema4a,Fpr2,Trem1,Egr3,Sema3c,Pik3cd,Nrp2,Lhx2,Lox,Saa3,Vasp,Lpar1,Ptafr,Cxcl10,Flt1,Cxcl9,Pdgfb,Scn1b,Cyfip1 |
| 3.612e-13 | -28.65 | Hepatitis B | KEGG pathways | mmu05161 | 143 | 43 | 7931 | 713 |
Casp8,Ikbke,Pik3cd,Tlr3,Irf7,Fas,Nfkbia,Ccne1,Mmp9,Tnf,Apaf1,Ifna2,Ifih1,Tlr2,Ifna1,Ddx58,Ifna6,Stat4,Myc,Ccnd1,Myd88,Ikbkg,Ifnb1,Egr3,Map2k4,Cycs,Casp3,Ifna5,Stat3,Ifnar1,Egr2,Stat1,Jun,Nfkb1,Src,Akt3,Cdkn1a,Map2k1,Il6,Stat2,Ifna4,Stat5a,Fos |
| 3.694e-13 | -28.63 | GSE3920_UNTREATED_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_UNTREATED_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP | 139 | 40 | 15632 | 1249 |
Egr3,Smox,Kdm6b,Zc3h12a,Dusp5,Trib3,Adora2b,Nr4a3,Cxcl10,Ccl4,Irak2,Dusp16,Cdkn1a,Pmepa1,Csrp1,Cd274,Rel,Adora2a,Cd69,Plk3,Nfkbiz,Prrg4,Egr1,Lif,Sgms2,Traf1,Rnd3,Plau,Myo10,Tnfaip3,Gadd45b,Ehd1,Tnf,Flrt3,Tet2,Traf2,Katna1,Egr2,Psd,Dusp4 |
| 3.694e-13 | -28.63 | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | MSigDB lists | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | 139 | 40 | 15632 | 1249 |
Isg15,Il4ra,Icam1,Prnp,Upp1,Plau,Gbp2,Mvp,Tagln,Ccl12,Agrn,Itgav,Flt1,Axl,Jun,Tank,Mmp14,Ly75,Il6,Pla2g4a,Ctsc,Vcan,Sele,Uchl1,Hmox1,Itga5,Ier3,Rcn1,Tgfbi,Tfec,Cdkn1a,Vegfc,Ltbp2,Eno2,Serpine1,Plod2,Ext1,Procr,Btg2,Ccrl2 |
| 3.707e-13 | -28.62 | GSE7460_TCONV_VS_TREG_LN_DN | MSigDB lists | GSE7460_TCONV_VS_TREG_LN_DN | 190 | 48 | 15632 | 1249 |
Cish,Nfkbie,Fgl2,Gpr68,Klf6,Axl,Cd83,Cd38,Gbp2,Mdfic,Gbp3,Rnf135,Cxcl2,Hk2,Slc4a7,Cd274,Hopx,Samsn1,Asns,Cd86,Vps54,Osbpl3,Glrx,Ptger4,Map3k8,Abcb1a,Irf4,Stard5,Phlpp1,Dusp4,Ahr,Nfkbiz,Ubash3b,Ppm1l,Trim14,Ccrl2,Tdrd7,Tnfrsf1b,Irf8,Zc3h12c,Gem,Casp4,Sh3bgrl2,Rgs1,Igf1r,Nfil3,Frmd6,Casp7 |
| 3.707e-13 | -28.62 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_DN | 190 | 48 | 15632 | 1249 |
Atp2b4,Rras2,Sgcb,Fbxo4,Ccnd2,Prnp,Gmppb,Pgs1,Lrp8,Cox17,Gadd45g,Cflar,Adam19,Mthfd2,Ifi35,Slc39a14,Mmd,Il18rap,Psme2,Irf8,Hk1,Stau1,Myd88,Rnf34,Batf,Ahsa1,Socs1,Magohb,Lif,Acvr1,Tnfsf8,Rab11fip1,Tnf,Il15ra,Stip1,Trafd1,Prkx,Pim1,Ak4,Cxcl10,Map3k8,Ptger4,Cd55,Wars,Phlpp2,Fubp1,4930523C07Rik,Gch1 |
| 3.828e-13 | -28.59 | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_DN | 177 | 46 | 15632 | 1249 |
Arhgef3,Tbc1d1,Sat1,Stat3,Ccng2,Hdac1,Acvr1,Glipr2,Calcrl,Apaf1,Brd2,Nampt,Txn1,Hk2,Tbc1d13,Traf3ip2,Atp10a,Gpr85,Osgin2,Ikbke,Tnfsf10,Thbs1,Acsl5,Plaur,Itgav,Ccl12,Morc3,Nfkbia,Kremen1,Usp25,Nxf1,Coa5,Cd80,Pim3,Kif9,Rbl1,Dach1,Gem,Tdrd7,C3,Ier3,Tax1bp1,Fam20c,Jak2,Pmepa1,Nlgn2 |
| 3.828e-13 | -28.59 | GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_DN | MSigDB lists | GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_DN | 177 | 46 | 15632 | 1249 |
Ptgir,Ebi3,Mmp25,Tnfaip2,Tnip1,Tnfrsf1b,Nfkb1,Rel,Ubr4,Psme2,Akt3,Tdrd7,Fas,Il4ra,Ccl22,Slamf7,Adar,Sdc4,Tap1,Klf7,Tnfrsf14,Sqstm1,Nfkbia,Gadd45b,Dnaja1,Cdc42ep4,Il1b,Map4k4,Plek,Txn1,Daam1,Slc2a6,Nrp2,Tbc1d13,Psme1,F11r,Tnfaip3,Mvp,Relb,Dusp1,Tank,Cd40,Tpst1,Rab9,Irgq,Tapbp |
| 4.152e-13 | -28.51 | positive regulation of interleukin-1 production | biological process | GO:0032732 | 56 | 23 | 20694 | 1406 |
Egr1,Hk1,Tlr2,Nod2,Nod1,Jak2,Ifnar1,Ifi205,Mndal,Nlrp3,Lgals9,Fzd5,Gsdmd,Malt1,Ifi211,Aim2,Ifi204,Ccl3,Ripk2,Casp1,Casp8,Hdac1,Casp4 |
| 4.215e-13 | -28.49 | regulation of protein localization | biological process | GO:0032880 | 1055 | 135 | 20694 | 1406 |
Ccl2,Tlr9,Hdac1,Glrx,Tnfsf4,Ezr,Il10,Cenpj,Mmp13,Vegfc,Ptger4,Adora2a,Socs1,Aim2,Rab11fip1,Fzd5,Dtx3l,Nr1h3,Mmp14,Rhoq,Stx6,Dnaja1,Ifih1,Hcar2,Nod2,Dnajb2,Src,Clec5a,Map4k4,Casp4,Gpr68,Map2k1,Hcls1,Sec24a,Casp1,Hap1,Ccne1,Arg2,Traf2,Lif,Nos2,Gpc1,Rhbdf2,Gbp4,Tnfsf15,Ripk2,Parp9,Lrp4,Tnfrsf1b,Swap70,Zc3h12a,Tomm70a,Clec4n,Nlrp3,Pid1,Tlr6,Jak2,Crkl,Uaca,Tlr2,Hmgn3,Frmd4a,Cd200,Clec4e,Ddx58,Tnfaip3,Serp1,Angpt1,Rasgrp1,Arid5a,Pml,Sik3,Syk,Pde3b,Lztfl1,Il1a,Ccl3,Mdfic,Tnf,Mapkbp1,Plk3,Cx3cl1,Rsad2,Cacna1d,Cd14,Gsdmd,Actb,Tbc1d1,Tlr1,Txn1,Cd40,Pfkl,Nlgn2,Fgr,Hk1,Rgcc,Rabgef1,Srgn,Ccl5,Irs2,Slc16a1,Rab9,Fbxo4,Prnp,Cacnb3,Cd34,Hsph1,Cd38,Hif1a,Ddx4,Il6,Ptgs2,Mmd,Sirt1,Mdm2,Cd274,Pim3,Il1b,Gpsm2,Pmaip1,Lgals9,Ifnar1,Ptch1,Gja1,Htr2b,Sqstm1,Cdk5r1,Prkce,Osm,Il4ra,Slc7a11,Lyn,Tnfrsf14,Klf7,Ppp2r5a |
| 4.223e-13 | -28.49 | GSE13522_WT_VS_IFNAR_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP | MSigDB lists | GSE13522_WT_VS_IFNAR_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP | 184 | 47 | 15632 | 1249 |
Trib1,Endod1,Casp7,Cd200,Ptgir,Gfi1,Pmepa1,Nfil3,Notch2,Rgs1,Adam19,Il10,Birc3,Hivep3,Isg20,Prnp,Cyth3,Nfkbiz,Dusp14,Samhd1,Plac8,Bcl2l11,Bcl2a1b,Dusp4,Cpd,Parp9,Irf4,Irgm2,Pkp4,Cmpk2,Bcl2a1a,Osbpl3,Hopx,Cd86,Dusp6,Stx11,Traf1,Gbp3,Mxd1,Ncoa7,Plagl2,Mdfic,Swap70,Glipr2,Bcl2a1d,Rsad2,Cish |
| 4.257e-13 | -28.49 | LU_IL4_SIGNALING | MSigDB lists | LU_IL4_SIGNALING | 88 | 31 | 15632 | 1249 |
Bcl6,Cish,Ly75,Il6,Gsr,Fgl2,Nek6,Egr1,Marcksl1,Nfkbiz,Hlx,Socs1,Sell,Il4ra,Kmo,Sla,Batf,Tnfaip3,Ccl5,H2-Eb1,Samsn1,Irf8,Cd86,Spint2,Cd69,Stat4,Tlr3,Ccl4,Cflar,Nfil3,Vegfc |
| 4.523e-13 | -28.42 | GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION | MSigDB lists | GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION | 1622 | 209 | 15632 | 1249 |
Plagl1,Nlrp3,Atf3,Egr1,Ciita,Adar,Fos,Nlrc5,Ezr,Agrn,Nod2,Irf4,Edn1,Pik3cd,Adrb2,Stat1,Actb,Cflar,Tnip1,Irf8,Ptch1,Ccne1,Jag1,Hivep3,Sirt1,Met,Ifi203,Ddx58,Il1a,Hif1a,Sertad3,Trim12c,Traf1,Irf2,Malt1,Lif,Notch1,Relb,Mdfic,Crlf3,Cd40,Hspa1a,Hsph1,Src,Mdm2,Kdm5b,Psma6,Cebpd,Egr2,Ptafr,Serpinb9,Cxcl10,Ptger4,Zc3h12a,Pf4,Thbs1,Bambi,Klf2,Arid4a,Nampt,Csf3,Pdgfb,Kat2b,Nr1h3,Klf7,Ahr,Rbl1,Cd34,Cd80,Nlrc4,Spic,Cited2,Hmga1,Psip1,Ifi204,Tlr9,Mtdh,Pim2,C3,Lhx2,Cav1,Pid1,Rel,Lmo4,Rnf14,Pou2f2,Trim14,Ifi211,Zeb1,Zfp36,Tab2,Zfp281,Prdm1,Aim2,Csrnp1,Cd38,Irak3,Plagl2,Sav1,Batf,Pbx1,Tcf4,Ifi209,Mecp2,Ythdf1,Stat3,Tnfsf8,Il18,Nr4a3,Pcgf5,Ripk2,Il1b,Fzd5,Serpine1,Map2k1,Osm,Irf7,Med21,Gja1,Trim13,Phip,Lrp8,Hinfp,Tet2,Jun,Nfkbia,Ikzf1,Spry2,Il6,Myc,Irf1,Acvr1b,Mafg,Tlr2,Hcls1,Asf1a,Il10,Rnf31,Bcl9,Plscr1,Icam1,Sphk1,Hhex,Ripk3,Nod1,Bmp2,Ifi205,Ifi213,Ifnar1,Acvr1,Acvrl1,Nr3c1,Rhoq,Larp1,Kdm6b,Dek,Cd86,Fubp1,Junb,Maff,Btg2,Ifi208,Ifi214,Nck1,Ifi207,Ets2,Plac8,Nr4a1,Eif2ak2,Sqstm1,Ifnb1,Stap1,H3f3b,Nfil3,Jak2,Arf4,Polr2g,Mndal,S100a8,Nfkb1,Ikbkg,Ahrr,Etv6,Slc9a1,Trim21,Csf1,Nfkbib,Med13,Etv5,Ncoa7,Traf5,Traf2,Serp1,Tnf,Klf6,Hdac1,Mafk,Tnc,Itgb8,Arid5b,Tlr3,Irak2,Nfkb2,Ppp1r15a,Fosb,Ccl5,Inhba,Fzd1,Trim26 |
| 4.564e-13 | -28.42 | positive regulation of macromolecule biosynthetic process | biological process | GO:0010557 | 1869 | 207 | 20694 | 1406 |
Dtx3l,Irf4,Med13,Hivep3,Edn1,Nod2,Hmga1,Nsd3,Hdac1,Irf1,Il10,Map2k4,Nr4a1,Hinfp,Acvr1,Irf2,Ptger4,Ets2,Ythdf1,Il18,Zc3h12a,Gfi1,Pid1,Notch1,Tlr2,Pim1,Hivep2,Csf3,Icosl,Dyrk2,Tnfsf8,Parp9,Rnf14,Arid5b,Max,Junb,Pou3f1,Cd74,Tlr1,Igf1r,Larp1,Psip1,Cd40,Mtdh,Mycl,Dr1,Nox1,Phip,Kat2b,Jmjd6,Irs2,Ifnb1,Il27,Ikzf1,Pml,Atf3,Pim2,Sertad3,Taf4b,Syk,Cited2,Stat4,Bambi,Fzd1,Pcgf5,Jun,Tcf4,Daxx,Ccl3,Il1a,Tnf,Arf4,Sirt1,Irf8,Hhex,Helz2,Ptch1,Lmo4,Ncoa7,Tnip1,Osm,Klf7,Pbx1,Ahr,Spn,Cd38,Hsph1,Fam129a,Plscr1,Rap2c,Klf6,Atm,Nfil3,Casz1,Fos,Ier2,Bcl9,Ahrr,Myc,Cebpd,Plagl2,Dcp1a,Pdgfrb,Fzd5,Nr1h3,Etv6,Zeb1,Fosb,Ifrd1,Klf2,Spen,Rhoq,Birc2,Csrnp1,Il15,Nupr1,Aff1,Tlr9,Adrb2,Pf4,Nfkbia,Slc9a1,Med21,Batf,Ccl2,Spic,Mllt6,Maml2,Mecp2,Arid4a,Cenpj,Rbpms,Stat5a,Plagl1,Ell2,Pou2f2,Plac8,Nlrp3,Tcea1,Stat1,Jak2,Tlr6,Inhba,Irf7,Hmgn3,Ddx58,Maff,Nr3c1,Stat3,Src,Egr3,Tfec,Stat2,Map2k1,Hcls1,Eif4g2,Lif,Pdgfb,Ptafr,Mafg,Wdr43,Ppp1r15a,Agrn,Kdm6b,Rgcc,Egr1,Zfp281,Nck1,Serp1,Myd88,Met,Acvrl1,Nampt,Arid5a,Etv5,Cacybp,Nlrc5,Egr2,Kdr,Mdfic,Cx3cl1,Polr2g,Tet2,Fubp1,Mapkapk2,Hmga2,Il1b,Tlr3,Ifnar1,Ikbkg,Relb,Nfkb1,Crlf3,Nr4a3,Prdm9,Thbs1,Lhx2,Fbxo4,Rel,Bmp2,Nfkb2,Il6,Hif1a,Acvr1b,Ciita,Jag1,Tnfrsf8 |
| 4.576e-13 | -28.41 | GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_DN | MSigDB lists | GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_DN | 191 | 48 | 15632 | 1249 |
Sik3,Ednrb,Slamf9,Dram1,Max,C3,Cdkn1a,Col27a1,Znfx1,Cited2,Gsdmd,Cd200r4,Mid1,Scarf1,Samd9l,Dusp4,Cxcl14,Parp9,Slfn8,Irgm2,Etv3,Ccnd2,Kat2b,Rtp4,Sass6,Lrp8,Usp25,Slc28a2,Vps54,Gch1,Snx2,Ak4,Frmd4a,Tapbpl,Dusp28,Cmpk2,Slfn9,Cd40,Birc2,Treml2,Dennd1b,Icam1,Ddx58,Stat2,Arg2,Irf2,Apaf1,Ifit1 |
| 4.710e-13 | -28.38 | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_17H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_17H_UP | 165 | 44 | 15632 | 1249 |
Traf1,Irs2,Rhoh,Csrnp1,Cdkn2d,Hlx,Tnfaip3,Sla,Pfkfb3,Trip10,Flrt3,Bcl2a1b,Sod2,Slc25a37,Plac8,Dusp4,Mlkl,Bcl2a1d,Kremen1,Itgb8,Arid5b,Tnip3,Ptgs2,Traf3ip2,Smox,Cd55,Sema4c,Ptges,Glrx,Il1b,Agpat4,Trem1,Plaur,Bcl2a1a,Vcam1,Cxcl1,Sik3,Casp4,Gch1,Tnfrsf1b,Rabgef1,Dach1,Nampt,Ddit4 |
| 4.947e-13 | -28.33 | GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 268 | 59 | 15632 | 1249 |
Ikbkg,Rasgrp1,Sirt1,Acsl1,Lpar1,Tlr9,Psmd10,Syk,Pik3r5,Flt1,Gadd45b,Map3k6,Pde5a,Gadd45g,Nod2,S1pr2,Spry2,Edn1,Cdk5r1,Mul1,Ccnd2,Tlr6,Mapkapk2,Atp2b4,Htr2a,Pdgfrb,Map2k1,Pik3r6,Fzd5,Dusp6,Rapgef2,Tnfsf15,Pdgfb,Fpr1,Pim1,Adora2b,Dusp5,Ripk2,Tlr3,Il1b,Htr2b,Thbs1,Irak2,Kitl,Cd40,Traf2,Tnf,Src,Hspa2,Ccnd1,Dbnl,Cd74,Tab2,Malt1,Mdfic,Daxx,Pdgfc,Bmp2,Nod1 |
| 5.016e-13 | -28.32 | MODULE_52 | MSigDB lists | MODULE_52 | 413 | 78 | 15632 | 1249 |
Isg15,Lif,Stau1,Etv5,Crim1,Myo10,Swap70,Birc2,Ifi209,Ifi205,Slc2a1,Tnf,Ifi213,Slc16a3,Cst7,Tnc,D1Ertd622e,Pnp2,Tgfbi,Mcm6,Lox,Gng12,Thbs1,Plat,Asns,Plk2,Serpine1,Ifit1bl2,Pde4b,Junb,Gdf15,Gja1,Dusp6,Maff,Hap1,Ddit4,Ifi208,Slc7a5,Pttg1,Sdc1,Ifi214,Tpx2,Gbe1,Ifi207,Angpt1,Rnd3,Gng11,Tspan3,Zyx,Cited2,Ifit1bl1,Slc7a11,Ccl12,Nqo1,Ctsc,Rai14,Myc,Ifi204,Ier3,Filip1l,Rac3,Cdkn1a,Ldlr,Cav1,Sema3c,Mndal,Plod2,Ikbkg,Mmd,Hat1,Eef1e1,Casp2,Ifi203,Cnn3,Procr,Ifi211,Plscr1,Trip13 |
| 5.164e-13 | -28.29 | positive regulation of lymphocyte differentiation | biological process | GO:0045621 | 108 | 32 | 20694 | 1406 |
Nfkbiz,Il15,Il4ra,Nfkbid,Malt1,Il18,Bcl6,Il1b,Pik3r6,Cd83,Nlrp3,Lgals9,Il15ra,Axl,Cd74,Mmp14,Il6,H2-Aa,Syk,Socs1,Ap3b1,Hlx,Ripk2,Il2rg,Stat5a,Egr3,Tnfsf9,Irf1,Ikzf1,Prdm1,Rasgrp1,Tnfsf4 |
| 5.232e-13 | -28.28 | GSE17721_CTRL_VS_CPG_2H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_2H_BMDC_DN | 185 | 47 | 15632 | 1249 |
Mthfd2,Mtdh,Mtmr14,Cd200,Fscn1,Jak2,Zc3h12c,Tnfrsf1b,Rnf19a,Procr,St3gal5,Ccnd2,Cx3cl1,P2ry14,Cited2,Sod2,Bcl2l11,Sqstm1,Ccl12,Mllt6,Kremen1,Fcgr2b,Slc44a1,Igsf6,St3gal1,Ptges,Samsn1,Serpine1,Igsf8,Snx10,Jarid2,Gch1,Reps1,Phlda1,Kmo,Arg2,Ier2,Itga4,Lif,Cd14,Cd40,Stat5a,Ehd1,Cst7,Ddhd1,Spryd7,Psma6 |
| 5.232e-13 | -28.28 | GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_UP | MSigDB lists | GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_UP | 185 | 47 | 15632 | 1249 |
Egr2,Rhoq,Sat1,Bcl2a1d,Mecp2,Fgl2,Casp1,N4bp1,Ifit2,Tank,Bcl6,Traf5,Mdfic,Ifit1,Ifih1,Usp18,Caml,Ccl5,Slc4a7,Nampt,Bcl2a1a,Hp,Nsmaf,Ttc39b,Phyh,Irgm2,Cpd,Ap3b1,Bcl2l11,Bcl2a1b,Itgav,Cyfip1,Psmd10,Tap1,Ahr,Pttg1,Cyth3,Plscr1,Trim21,Kctd12,Rnf19a,Nfkb1,Tor3a,Irf8,Adam19,Gfi1,Cd200 |
| 5.232e-13 | -28.28 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_DN | 185 | 47 | 15632 | 1249 |
Ifit2,Dync1h1,Psmb9,Hspa1a,Tbc1d1,Mafk,Bcl2a1d,Tapbp,Rsad2,Itga4,Usp18,F11r,Traf1,Crlf3,Daxx,Stau1,Myadm,Rnaset2a,Irf7,St3gal1,Clec4d,Vcam1,Bcl2a1a,Cldnd1,Cmpk2,Bcl2a1b,Agrn,Psip1,Bcl2l11,Tor1aip2,Nfkbiz,Ccl22,Tap1,Tor3a,Irf8,Trim21,Isg20,St3gal5,Stx6,Cacnb3,Azi2,Fam20c,Idi1,Hcls1,Rnaset2b,Frmd6,Abcc1 |
| 5.232e-13 | -28.28 | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_DN | MSigDB lists | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_DN | 185 | 47 | 15632 | 1249 |
Dock10,Rgs14,Arid5a,Crlf3,Irak3,Daxx,Hvcn1,Itga4,Ddx58,Calcrl,Usp18,Gpr132,Inpp5b,Dgka,Slc4a7,Ifit1bl2,Irf7,Osm,Klf2,Tnfsf10,Cmpk2,Mob3b,Peli1,Abcb1a,Irgm2,Samd9l,Rin2,Pik3r5,Trim36,Ifit1bl1,Znfx1,Pgs1,Nck1,Rtp4,Il4ra,Slc30a1,Etv3,Ubash3b,Akt3,Rasgrp1,Xaf1,Rnf19a,Gbp7,Clcf1,Plekhn1,Dyrk2,Pik3cd |
| 5.232e-13 | -28.28 | GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN | 185 | 47 | 15632 | 1249 |
Minpp1,Cycs,Pnp2,Bcl2a1d,Tnf,Plagl2,Arg2,Traf1,Slc7a5,Rapgef2,Daam1,Hopx,Snapc1,Bcl2a1a,Il1b,Dusp5,Nsmaf,Spry2,Irf4,Dusp2,Ifrd1,Cox17,Dusp4,Ezr,Hivep2,Bcl2a1b,Rras2,Prdx1,Hinfp,Ahr,Dusp14,Atf3,Prnp,Nlrp3,Timeless,Il18rap,Tnfrsf1b,Rnf14,Nfkb1,Tnfsf14,Rel,Gem,Ccl4,Gfi1,Cd200,Acsl1,Ier3 |
| 5.275e-13 | -28.27 | GO_POSITIVE_REGULATION_OF_PROTEOLYSIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEOLYSIS | 343 | 69 | 15632 | 1249 |
Tnfsf15,Ifi208,Plk2,Tnfsf10,Keap1,Il1b,Rnf19b,Psmb6,Smc5,Trib3,Cycs,Stat3,Casp3,Mdm2,Psma6,Ifi213,Tnf,Casp1,Traf2,Psmb9,Ifi205,Ifi209,Nod1,Apaf1,Plk3,Ube2e1,Psme1,Aim2,Rnf139,Pml,Psmb10,Ifi211,Psme2,Sirt1,Rnf19a,Egln3,Ifi203,Casp2,Psmb8,S100a8,Ankib1,Rnf14,Tnfrsf1b,Cav1,Casp8,Mndal,Jak2,Fam162a,Dnajb2,Ptk2,Casp7,C3,Trib1,Ifi204,Mefv,Ctsc,Mmp14,Myc,Ift57,Rnf114,Bcl2l11,Psmd10,Nlrc4,Gclc,Ifi207,Fas,Mul1,Ifi214,Nlrp3 |
| 5.342e-13 | -28.26 | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 172 | 45 | 15632 | 1249 |
Pde4b,Higd1a,Sipa1l1,Trim26,Pdlim7,Stx11,Rnf19b,Fcho2,Serpinb9,Plcl2,Sp110,Dusp1,Ifnar1,Abcc5,Dse,Dbnl,Marcksl1,Ier2,Pml,Ddx58,Slc39a13,Sell,Fgr,Myd88,Rgs3,Jdp2,Nfkb1,P2ry2,Srxn1,Etv6,Stx6,Oasl1,Adam19,H3f3b,Eif2ak2,Flt1,Nlrc4,Rhof,Dnaja1,Gpr35,Sdc2,I830077J02Rik,Bcor,Il4ra,Zc3hav1 |
| 5.575e-13 | -28.22 | Legionellosis | KEGG pathways | ko05134 | 58 | 26 | 7931 | 713 |
Cxcl3,Tlr2,Cxcl1,Nfkb1,Apaf1,Hspa1b,Casp1,Tnf,Bnip3,Nlrc4,Nfkbia,Cxcl2,Casp8,Cycs,Casp3,Il18,Cd14,Casp7,Il1b,Il12b,C3,Nfkb2,Hspa1a,Myd88,Il6,Hspa2 |
| 5.575e-13 | -28.22 | Legionellosis | KEGG pathways | mmu05134 | 58 | 26 | 7931 | 713 |
Tlr2,Cxcl1,Cxcl3,Hspa1b,Apaf1,Nfkb1,Nlrc4,Bnip3,Nfkbia,Tnf,Casp1,Casp8,Cxcl2,Casp3,Cycs,Casp7,Cd14,Il18,Il6,Hspa2,Hspa1a,Nfkb2,Myd88,C3,Il1b,Il12b |
| 5.635e-13 | -28.20 | positive regulation of protein serine/threonine kinase activity | biological process | GO:0071902 | 312 | 59 | 20694 | 1406 |
Map3k6,Cd40,Edn1,Spry2,Mtcp1,Nod2,Rgcc,Pde5a,Gadd45g,Htr2a,Gdf15,Fzd5,Pdgfrb,Cd74,Il1rn,Gadd45b,Atp2b4,Syk,Map3k8,Kitl,Tnf,Mapkbp1,Eif2ak2,Mdfic,Pik3r5,Adrb2,Tlr9,Met,Rasgrp1,Map2k4,Crkl,Tlr6,Jak2,Htr2b,Pim1,Ccnd1,Cdk5r1,Psmd10,Mlkl,Pdgfc,Sirt1,Lgals9,Il1b,Pik3r6,Pdgfb,Flt1,Traf2,Ccnd2,Higd1a,Acsl1,Mul1,Lpar1,Ripk2,Irgm2,Rapgef2,Thbs1,Src,Bmp2,Map2k1 |
| 5.640e-13 | -28.20 | GSE17721_0.5H_VS_24H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_24H_POLYIC_BMDC_DN | 192 | 48 | 15632 | 1249 |
Spen,Zeb1,Tnfrsf1b,Pdk3,Irf8,Cd82,Arf4,Plekhn1,Cd200,Mmp14,Katna1,Ppp2r5a,Ift57,Trmt1l,Zbp1,Rbm43,Gng11,Clec4e,Prdx1,Slc28a2,Stxbp1,Abr,Etv3,Stxbp3,Oas2,Snx2,G3bp2,Ccl5,Snx10,Cnp,Slc29a3,Keap1,Epsti1,Ripk2,Smc5,Smox,Atp10a,Clec5a,Chic2,Slc39a4,Fgl2,Ddhd1,Ttc39c,Cd14,Prpf38a,Mcmbp,Notch1,Itga4 |
| 5.640e-13 | -28.20 | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN | 192 | 48 | 15632 | 1249 |
Vcan,Optn,Hivep2,Trp53i11,Ifi207,Tpi1,Ifi214,Psme2,Ampd3,Ifi211,Trim21,Slc9a1,Ifi203,Tnfrsf1b,S100a8,Eno2,Mndal,Tnfaip2,Rgs1,Ldlr,Fscn1,Ptgir,Mmp9,Ifi204,Ifi44,Sat1,Cebpd,Acvrl1,Ifi213,Ifi205,Ifi209,Cd14,Myd88,Rhoc,Nupr1,Sell,Isg15,Tlr1,Ifi208,Ddit4,Oas2,Maff,Ccl5,Plk2,Ppp1r15a,Glrx,Plaur,Rtn1 |
| 5.871e-13 | -28.16 | leukocyte chemotaxis | biological process | GO:0030595 | 128 | 35 | 20694 | 1406 |
Cxcl1,Cx3cl1,Ccl3,Ccl7,Pdgfb,Syk,Cxcl9,Flt1,Ccl4,Cxcl10,Cx3cr1,S100a8,Ccr1,Ccl12,Slamf8,Pf4,Gpr35,Ccl2,Trem1,Sbds,Cxcl3,Cxcl2,Cxcl11,Ccl5,Csf3r,Ccl9,Il1b,Ch25h,Il1rn,Ccr3,Pde4b,Ccl8,Ccl22,Ednrb,Itga9 |
| 5.924e-13 | -28.15 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_DN | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_DN | 166 | 44 | 15632 | 1249 |
Dse,Tpst1,Etv5,Rgs3,Myo10,Tnfaip3,Plagl2,Hck,Marcksl1,Mxd1,Ch25h,Calcrl,Ddit4,Tbc1d13,Csrp1,Fzd5,Samsn1,Rrs1,Ptges,St3gal1,Fpr1,Ccl2,Myc,Pdpn,Vcan,Cpd,Trim36,Nfkbia,Pilra,Clec4e,Dusp14,Pstpip2,Procr,Plscr1,Met,S100a8,Ltbp2,P4ha1,Gna15,Marco,Pid1,Cd82,Mafg,Sema4a |
| 5.935e-13 | -28.15 | GSE30083_SP3_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP3_VS_SP4_THYMOCYTE_DN | 179 | 46 | 15632 | 1249 |
Fam43a,Spry2,Rin2,Cd200r4,Evl,Ubash3b,Sdc4,Tor3a,Tnfsf14,Zc3h12c,Irf8,Gem,Slamf9,Mmd,Stat4,Oas1a,Il18rap,Syne2,Tdrd7,Mppe1,Rcn1,Tagap,Parp8,Casp1,Dse,Rhoq,Ifi44,Fgl2,Ccnd1,Itga4,Hhex,Lif,Traf5,1600014C10Rik,Cd38,Rhoc,Snx10,Plek,Daam1,Hopx,Irf7,Tlr1,Oas1g,Traf3ip2,Ttc39b,5430427O19Rik |
| 6.053e-13 | -28.13 | positive regulation of leukocyte mediated immunity | biological process | GO:0002705 | 170 | 41 | 20694 | 1406 |
C3,Il1b,Il12b,Nlrp3,Nectin2,H2-T24,Fzd5,Malt1,Il18,Nod2,H2-T22,Il4ra,Ddx58,Tap2,H2-Q4,H2-Q7,Clcf1,Fgr,Cd40,H2-T10,Pvr,Adora2b,H2-Q6,H60b,Arid5a,Rasgrp1,Tnfsf4,Il18rap,Fcgr1,H2-M2,Rsad2,Cxcl1,Stat5a,Tnf,Il6,Klrk1,Raet1e,Syk,Traf2,Stxbp1,Ptafr |
| 6.103e-13 | -28.12 | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP | MSigDB lists | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP | 117 | 36 | 15632 | 1249 |
Ifi203,Oas2,Oas1a,G3bp2,Csf3,Jag1,Ifi208,Ifi211,Mndal,Pid1,Plk2,S100a8,Slc4a7,Dcbld2,Thbs1,Clic4,Pcdh7,Ifi204,Ptgs2,Il13ra1,Oas1g,Hmgcs1,Dusp4,Pdpn,Tnc,Ifi205,Ifi209,Ifi213,Ifi207,Gng11,Ifi214,Ddx58,Ccnd2,Prnp,Palld,Nupr1 |
| 6.342e-13 | -28.09 | GO_WOUND_HEALING | MSigDB lists | GO_WOUND_HEALING | 447 | 82 | 15632 | 1249 |
Hmox1,Lox,Plat,Serpinb2,Plaur,Dcbld2,Pf4,Il1b,Plek,Csrp1,Gja1,Lcp2,Pik3r6,Pdgfrb,Pdgfb,Stxbp3,Ifna6,Maff,Adora2a,Dgka,Irf2,Il1a,Hif1a,Pdgfc,Notch1,Ifna2,Rhoc,Src,Ehd1,Klf6,Axl,Timp1,Itpr1,P2ry12,Cd40,Casp3,Tnc,Hdac1,Mafk,Acvrl1,Dgkh,Itga5,C3,Irf1,Itga9,Lyn,Mafg,Adrb2,Actb,Jak2,Cflar,Notch2,H3f3b,Prkar2b,S100a8,Cav1,Gna15,P2ry2,Procr,Bcl9,Plscr1,Stxbp1,Sdc1,Cx3cl1,Papss2,Ifna1,Plau,Cd34,Sdc4,F10,Enpp4,Pik3r5,Syk,Slc7a11,Pdpn,Il6,Prkce,Sdc2,Ifrd1,Ap3b1,Ifna5,Ifnb1 |
| 6.471e-13 | -28.07 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_UP | 186 | 47 | 15632 | 1249 |
Lyn,Irf1,Socs3,Kif5c,Mtdh,Nfil3,Gfi1,Ccl4,Jak2,Ogfr,Cep350,Birc3,Procr,Il4ra,Fcgr1,Il15,Gadd45g,Il18bp,Il6,Map3k8,Tgfbi,Rcan1,Ptgs2,Ptger4,Gng12,Map2k1,Cd86,Ppp1r15a,Gja1,Brwd3,Slc4a7,Junb,Hk2,Gpr132,Sphk1,Gbp3,Rhoh,Mcoln2,Itga4,Hlx,Relb,Myd88,Csf3r,Cebpd,Sele,Fgl2,Errfi1 |
| 6.473e-13 | -28.07 | GO_LEUKOCYTE_CELL_CELL_ADHESION | MSigDB lists | GO_LEUKOCYTE_CELL_CELL_ADHESION | 248 | 56 | 15632 | 1249 |
Rhoh,Malt1,Itga4,Jmjd6,Psmb10,Icam1,Cd74,Batf,Ifna2,Relb,Ripk3,Ifnar1,Tnf,Tnfsf8,Rsad2,Treml2,Sele,Ripk2,Ptger4,Il12b,Clec4d,Vcam1,Il1b,Ccl5,Cd86,Fzd5,Ifna6,Icosl,Egr1,Nck1,Fas,Clec4e,Cd80,Il15,Ifna1,Olr1,Syk,Spn,Ezr,Ptpn2,Il6,Irf4,Ifna5,Ifnb1,Itga5,Ebi3,Tnfsf4,Sema4a,Pik3cd,Azi2,Irf1,Tnip1,S100a8,Casp8,Itgal,Tnfsf14 |
| 6.501e-13 | -28.06 | positive regulation of adaptive immune response | biological process | GO:0002821 | 142 | 37 | 20694 | 1406 |
H2-Ab1,H2-M2,Irf1,Fcgr1,Arid5a,Tnfsf4,Pvr,H2-Q6,Traf2,Il6,Tnf,Hlx,Ripk2,Rsad2,Fzd5,Malt1,Il18,Sirt1,H2-T24,Il12b,Il1b,Nectin2,Cd274,Nlrp3,C3,Cd74,H2-T10,Nfkbiz,Cd40,Clcf1,H2-Q7,Tap2,H2-Q4,H2-T22,Il12rb1,Nod2,Nfkbid |
| 6.581e-13 | -28.05 | negative regulation of inflammatory response | biological process | GO:0050728 | 149 | 38 | 20694 | 1406 |
Ptger4,Socs3,Abr,Cx3cl1,Adora2a,Slamf8,Smpdl3b,Spn,Adrb2,Fpr2,Siglece,Cx3cr1,D1Ertd622e,Il10,Ldlr,Fcgr2b,Aoah,Uaca,Acod1,Tnfaip3,Calcrl,Nfkb1,Nod2,Cd200,Rabgef1,Ptpn2,Tnfrsf1b,Ctla2a,Ier3,Zc3h12a,Zfp36,Acp5,Cst7,Lgals9,Il12b,Mefv,Nlrp3,Nr1h3 |
| 6.674e-13 | -28.04 | GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_UP | MSigDB lists | GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_UP | 173 | 45 | 15632 | 1249 |
Fgr,Myd88,Cd38,Clmp,Tank,Cp,Egr2,C1ra,Parp3,Pcdh7,Gng12,Ptges,Slc4a7,Txn1,Slc13a3,Tuba4a,Gpr132,Ddit4,Rab10,Slc25a12,Spint2,Gbe1,Dmxl2,Klf7,Pik3r5,Psmd10,Msr1,Ctsc,Pdpn,Cpd,Il13ra1,Ptgir,Odc1,Mthfd2,Gpd2,Pdzd11,Jak2,Idi1,Tmem123,Trem1,Stard7,Hsd17b7,Jdp2,Lcn2,Procr |
| 6.939e-13 | -28.00 | GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_DN | MSigDB lists | GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_DN | 193 | 48 | 15632 | 1249 |
Nr1h3,Ubash3b,Tap1,Dnase1l3,Zbp1,Slamf7,Aoah,Spn,Nlrc5,Scarf1,Il18bp,Cd200r4,Dusp2,Mthfd2,Irf1,Parp11,Stat1,Ogfr,Gem,Plekhg1,Stat4,Cd180,Stat2,Pml,Itga4,Hck,Gbp2,Traf5,Rbbp8,Traf2,Cst7,Apobec3,Acvrl1,Batf2,Setdb2,Pnp2,Phgdh,Il2rg,Parp3,Keap1,Epsti1,Lacc1,Cldnd1,Atp6v1d,Tap2,Ccl5,Slc13a3,Il12rb1 |
| 6.939e-13 | -28.00 | GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_DN | 193 | 48 | 15632 | 1249 |
Srxn1,Plscr1,Rnf19a,Tdrd7,Met,Birc3,Rnf14,Irf8,Zc3h12c,Znrf1,Fam20c,Kdr,Tnip1,Dusp16,Cdkn1a,Frmd6,Mthfd2,Gpd2,Nfkbia,Gadd45b,Nr4a1,Sbds,Pim3,Gpc1,Cd80,Nfkbiz,Fas,Ccnd2,Cdk5r1,Parp12,Junb,Brd2,Pdgfrb,Cxcl1,Vcam1,Fam53c,Zc3h12a,Tmem229b,Adora2b,Ptgs2,Map3k8,Pde1b,Mecp2,Parp8,Mapkbp1,Apaf1,Prdm1,Icam1 |
| 7.074e-13 | -27.98 | Adaptive Immune System | REACTOME pathways | R-MMU-1280218 | 594 | 105 | 8608 | 757 |
H2-T10,Psme1,Cd40,Psmb6,Cd74,H2-Q7,Nfkbie,Sell,Fcgr1,Cd300e,Treml2,Cd80,Itga4,H2-Q6,Trem1,Ier3,Cd86,Cd274,Map3k8,Clec2d,Treml4,Ppp2r5a,Tab2,Cdkn1a,Tapbp,Tnfrsf14,Rel,Lcp2,Pik3cd,H2-Eb1,Psmd10,Icosl,Klrk1,Rap1gap2,Psmb10,Vasp,Nectin2,Cd300lf,Herc6,H2-T24,Ppp2r1b,Trim36,Nr4a1,Fbxo4,Psme2b,Tap2,Lyn,Ifitm1,Kif3c,C3,Spsb1,Lnpep,Rasgrp1,Tap1,Psme2,Trib3,Psma6,Mdm2,Met,Znrf1,Psmb8,Itgal,Ripk2,Trim21,Itgav,Nfkbia,Dync1h1,Pdgfrb,Rictor,Evl,Irs2,Kitl,Pdgfb,Cd34,Rnf114,Itpr1,Psmb9,H2-M2,H2-Aa,Malt1,H2-Q4,Phlpp1,Sec24b,Nck1,Ikbkg,Cenpe,Slamf7,Rnf19b,Dtx3l,Syk,Cd200,Nfkbib,H2-T22,Dync1i2,Ptprj,H2-Ab1,Vcam1,Sec24a,Rnf19a,Icam1,Uba7,Phlpp2,Src,Cd200r4,Nfkb1 |
| 7.227e-13 | -27.96 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043281 | 216 | 47 | 20694 | 1406 |
Malt1,Myc,Birc2,Serpinb9,Fas,Cdkn2d,Nod1,Tnfsf10,Ift57,Apaf1,Plaur,Nr4a1,S100a8,Birc3,Casp8,Pml,Rnf34,Syk,Tnf,Adora2a,Rffl,Fam162a,Mmp9,Sirt1,Mdm2,Nlrp3,Pmaip1,Jak2,Prdx5,Stat1,Nlrc4,Uaca,Tnfsf14,Cycs,Hspa1b,Src,Bcl2l11,Casp4,Thbs1,Casp1,Il6,Ptgs2,Mul1,Ripk2,Bcl2a1d,Tnfsf15,Cflar |
| 7.243e-13 | -27.95 | HARRIS_HYPOXIA | MSigDB lists | HARRIS_HYPOXIA | 79 | 29 | 15632 | 1249 |
Hk1,Nfkb1,P4ha1,Txn1,Pdgfb,Hk2,Mmp13,Ldha,Hmox1,Ptgs2,Pgk1,Cdkn1a,Plaur,Pfkl,Tagln,Ccl12,Flt1,Eno1,Slc2a1,Jun,Fos,Il6,Cp,Bnip3,Sat1,Edn1,Ccng2,Lrp8,Hif1a |
| 7.266e-13 | -27.95 | GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 573 | 97 | 15632 | 1249 |
Dbnl,Psma6,Ccnd1,Hsph1,Src,Cd40,Psmb9,Bmp2,Nod1,Mdfic,Ripk3,Daxx,Ube2e1,Malt1,Psme1,Fgr,Tnfsf15,Pdgfb,Txn1,Pik3r6,Thbs1,Dusp5,Fpr1,Pim1,Edn1,Spry2,Nod2,Pik3r5,Cenpe,Map3k6,Flt1,Psmd10,Htr2a,Angpt1,Atp2b4,Mark2,Lrp8,Tlr6,Mapkapk2,Arrdc4,Ccnd2,Rasgrp1,Sirt1,Psmb8,Prkar2b,Acsl1,Adrb2,Hspa2,Tnf,Traf2,Pdgfc,Psmb10,Tab2,Cd74,Rapgef2,Ccl5,Dusp6,Pdgfrb,Map2k1,Fzd5,Lcp2,Irak2,Kitl,Pilrb1,Htr2b,Il1b,Psmb6,Ripk2,Crkl,Tlr3,Map3k8,Trib3,Adora2b,Stap1,Gadd45g,Pde5a,S1pr2,Syk,Gadd45b,Eif2ak2,Sdc4,Pilrb2,Tpx2,Mul1,Cdk5r1,Psme2,Csf1,Mmd,Ikbkg,Dcun1d3,Lmo4,Jak2,Cdkn1a,Tlr9,Ptk2,Lyn,Lpar1 |
| 7.369e-13 | -27.94 | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP | MSigDB lists | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP | 180 | 46 | 15632 | 1249 |
Cd300lf,Cacna1d,Dnajb2,Pmepa1,Vrk2,Flnb,Tnfrsf1b,Casp4,Il10,Zc3h12c,Cd80,Pde3b,Dnase1l3,Tmem176b,Arl4a,4932438A13Rik,Sqstm1,Rapgef5,D16Ertd472e,Cyfip1,Prkx,Ralgds,Plaur,Lacc1,St7,Tmeff1,Nrp2,Rapgef2,Ccl5,Plek,Junb,Txn1,Cd86,Asns,Samsn1,Lcp2,Ncoa7,Dusp8,Casp3,Hspa2,Fgl2,Glipr2,Ehd1,Dusp1,Hspa1a,Arid5a |
| 7.686e-13 | -27.89 | GO_ZYMOGEN_ACTIVATION | MSigDB lists | GO_ZYMOGEN_ACTIVATION | 112 | 35 | 15632 | 1249 |
Apaf1,Ifi207,Nod1,Mul1,Ifi214,Nlrp3,Pml,Fas,Ift57,Mmp14,Cycs,Casp3,Ifi209,Ifi205,Nlrc4,Traf2,Bcl2l11,Casp1,Tnf,Ifi213,Fam162a,Plat,Tnfsf10,Jak2,Ifi204,Casp7,Egln3,Casp2,Ifi203,Ifi208,Tnfsf15,Ifi211,Mndal,Casp8,S100a8 |
| 7.990e-13 | -27.86 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_1H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_1H_UP | 187 | 47 | 15632 | 1249 |
Procr,Pstpip2,Plscr1,Cep350,Birc3,Ednrb,Dusp16,Nfil3,Jak2,Ccl4,Irf1,Dck,Socs3,Gadd45g,Fcgr2b,Il6,Adar,Il4ra,Cdkn2d,Tmeff1,Noc4l,Cd86,Ppp1r15a,Map2k1,Ccr1,Gja1,Il1rn,Rcan1,Map3k8,Cxcl10,Ptger4,Sele,Fgl2,Errfi1,Cebpd,Phgdh,Csf3r,Hck,Batf,Myd88,Sphk1,Gbp3,Socs1,Hlx,Ch25h,Rhoh,Mcoln2 |
| 8.052e-13 | -27.85 | LEONARD_HYPOXIA | MSigDB lists | LEONARD_HYPOXIA | 42 | 21 | 15632 | 1249 |
Serpine1,Slc2a1,Slc16a3,P4ha1,Dusp1,Junb,P4ha2,Hk2,Ccng2,Rasgrp1,Slc7a5,Bnip3,Pdgfb,Sap30,Nr3c1,Ddit4,Jmjd6,Adora2b,Ak4,Pgk1,Nfil3 |
| 8.195e-13 | -27.83 | OKUMURA_INFLAMMATORY_RESPONSE_LPS | MSigDB lists | OKUMURA_INFLAMMATORY_RESPONSE_LPS | 161 | 43 | 15632 | 1249 |
Rel,Birc3,Il18rap,Rasgrp1,Akt3,Acsl1,Cd200,Tnfsf4,Tnip1,Tmem123,Jak2,Fscn1,Orai2,Cited2,Bcl2l11,Slc7a11,Optn,Olr1,Me1,Pilrb2,Sdc4,Ccl5,Rgl1,Slc4a7,Txn1,Phlda1,Tlr1,Ptger4,Thbs1,Pilrb1,Dse,Stat5a,Dock10,Cebpd,Rab9,Sphk1,Arg2,Atp11a,Marcksl1,Relb,Tnfaip3,Etv5,Tnfrsf8 |
| 8.205e-13 | -27.83 | positive regulation of leukocyte migration | biological process | GO:0002687 | 143 | 37 | 20694 | 1406 |
Itga4,Mmp9,Swap70,Cd74,Sele,Mmp14,Lgals9,Il1b,Cxcl14,Edn1,Pla2g7,Sell,Tnfrsf14,Serpine1,Tlr2,Icam1,Tnfsf14,Csf1,Ccl5,Spn,Thbs1,Ccl2,Ccr1,Fpr2,Tnfsf4,Ccl12,Ptprj,Ptger4,Vegfc,Ptafr,Cmklr1,Ccl4,Cxcl10,P2ry12,Kitl,Il1a,Cx3cl1 |
| 8.245e-13 | -27.82 | positive regulation of cytokine secretion | biological process | GO:0050715 | 150 | 38 | 20694 | 1406 |
Lgals9,Il1b,Tlr1,Cd274,Nlrp3,Clec4n,Fzd5,Gsdmd,Cd14,Tnfrsf14,Nod2,Il4ra,Osm,Ddx58,Clec4e,Rgcc,Tlr2,Hk1,Fgr,Ifih1,Htr2b,Ifnar1,Il10,Casp1,Arid5a,Rasgrp1,Casp4,Cd34,Clec5a,Src,Ripk2,Tnfsf15,Aim2,Tnf,Il1a,Ccl3,Syk,Ptger4 |
| 8.522e-13 | -27.79 | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP | 194 | 48 | 15632 | 1249 |
Pilra,Ahr,Egr1,Nlrp3,Peli1,Igsf6,Rin2,Aoah,Rab32,Sod2,Cyfip1,Tnfaip2,Trem1,Nfil3,Trib1,Acsl1,Ier3,Rab20,Tlr2,Hk1,Tnfrsf1b,Pid1,Adap2,Cd14,Gbp2,Hck,Upp1,Slco3a1,Fgr,Sat1,Fgl2,Arhgap26,Cebpd,Casp1,Timp1,Csf3r,Bcl6,Il1rn,Hmox1,Rtn1,Fpr1,Snx2,Hk2,Nampt,Slc31a2,Tuba4a,Gch1,Cd86 |
| 9.114e-13 | -27.72 | GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 998 | 144 | 15632 | 1249 |
C3,Mmp9,Cpeb4,Lyn,Trib1,Ifi204,Cdkn1a,Pmepa1,Dnajb2,Dusp16,Ednrb,Ppp1r15b,Nfkb1,Atm,Casp8,Mndal,Nos2,Pid1,Cav1,Mov10,Zfp36,Slpi,Psme2,Ifi211,Trim21,Bcor,Usp25,Cdkn2d,Nck1,Ifi214,Ubash3b,Kat2b,Tspo,Dusp14,Spred1,Ifi207,Itgav,Eif2ak2,Gadd45b,Ptpn2,Dnaja1,Nlrc4,Dusp2,Dusp4,Psmb6,Trib3,Plat,Il1b,Myadm,Dusp6,Serpine1,Flrt2,Ppp1r15a,Ddit4,Spint2,Inhba,Rnf139,Parp10,Psmb10,Rnf34,Tnfaip3,Mvp,Irak3,Rgs3,Tnf,Ifi209,Stat3,Prdx5,Mecp2,Errfi1,Tlk2,Socs3,Aida,Tnip1,Socs7,Prkar2b,Igf1r,Psmb8,Rabgef1,Birc3,Il10,Tnfsf14,Ifi203,Sirt1,Atf3,Pttg1,Prnp,Gclc,Adar,Angpt1,Atp2b4,Flrt3,Ezr,Jun,Psmd10,Prkce,Il6,Myc,Spry2,Edn1,Zc3h12a,Dusp5,Uchl1,Ptprj,Cd55,Serpinb9,Thbs1,Serpinb2,Plaur,Igf2bp2,Jarid2,Samsn1,Nmi,Ifi208,Btg2,Hap1,Pml,Lif,Psme1,Ube2e1,Hhex,Socs1,Isg15,Kdm4a,Crim1,Cst7,N4bp1,Ifi213,Dusp1,Src,Hsph1,Ifi205,Hspa1a,Birc2,Swap70,Rgs14,Timp1,Psmb9,Dusp8,Cish,Rffl,Casp3,Psma6,Mdm2 |
| 9.132e-13 | -27.72 | GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_DN | 181 | 46 | 15632 | 1249 |
Slc29a3,Trafd1,Epsti1,Igf2bp2,Il12b,Grina,Ube2l6,Tyk2,Car13,Slc13a3,Rhoc,Gbp3,Psmb10,Tulp3,Rab9,Gbp4,Gbp9,B3gnt5,Rsad2,Apobec3,Axl,Serp1,Swap70,Psmb9,Fam20c,Fscn1,Tmem219,Cd200,Slc25a22,Ms4a6d,Cysltr2,Met,Stat4,Plekha2,Il10,Rel,Slc28a2,Chmp4b,Aldh1b1,Gmppb,Ccl2,Ankrd24,Il18bp,Agrn,Jun,Znfx1 |
| 9.132e-13 | -27.72 | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | 181 | 46 | 15632 | 1249 |
Wars,Slc25a12,Trim26,Daam1,Lad1,Rrs1,Map2k1,4930523C07Rik,Zhx2,Snapc1,Cox18,Usp42,Naa25,Herc6,Xkr8,Ptger4,Parp3,Dse,Swap70,Myd88,Batf,Icam1,Zfp281,Sell,Gbp3,Trim12c,Hivep3,Isg20,Akt3,Trim14,Rims3,Fam162a,Jak2,Notch2,Sema4a,Filip1l,Tmod3,Parp9,Samd9l,Ctsc,Spn,Eif2ak2,Nr4a1,Agrn,Tap1,Egr1 |
| 9.132e-13 | -27.72 | GSE34156_TLR1_TLR2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_UP | MSigDB lists | GSE34156_TLR1_TLR2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_UP | 181 | 46 | 15632 | 1249 |
Slamf9,Pstpip2,Lyn,Mefv,Tlr2,Il13ra1,Vrk2,Plekhn1,Cd300lf,Actb,Dock4,Msr1,Syk,Rin2,Vcan,Igsf6,Prkce,Kcnj2,Dmxl2,Cyth3,Fpr2,Clec4e,Pilra,Plau,Cd86,Dusp6,Ccr1,Cxcl2,AA467197,Wars,Nrp2,Ptafr,Tgfbi,Hmox1,Tfec,Lacc1,Dcbld2,Clic4,Dse,Timp1,Src,Slc25a37,Sat1,Hck,Cd14,Gnb4 |
| 9.212e-13 | -27.71 | regulation of toll-like receptor signaling pathway | biological process | GO:0034121 | 63 | 24 | 20694 | 1406 |
Gfi1,Nr1h3,Tlr1,Cd300lf,Irak3,Irf4,Cav1,Irf7,Lyn,Tnfaip3,Nod2,Trim30a,Tlr2,Tlr3,Acod1,Tlr6,Smpdl3b,Treml4,Nfkbil1,Tlr9,Peli1,Irf1,Rsad2,Wdfy1 |
| 9.441e-13 | -27.69 | ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF | 434 | 80 | 15632 | 1249 |
Myd88,Lipg,Crim1,Ier2,Plk3,Lif,Ddx58,Zfp281,Hif1a,Tnc,D1Ertd622e,Sat1,Itgb8,Egr2,Zfp800,Stk40,Ehd1,Klf6,Arhgef3,Homer1,Birc2,Pcdh7,Snapc1,Osbpl3,Thbs1,Serpinb2,Vegfc,St3gal1,Shisa3,Smox,Rnf19b,Ptger4,Pim1,Arid5b,Ext1,Ddit4,Parp12,Hap1,Jarid2,Csrp1,Daam1,Cd274,Herc3,Pim3,Slc25a25,Sdc4,Plau,Gclc,Klf7,Ahr,Bcor,Palld,Irs2,Parp14,Spry2,Lrch1,Myc,Dusp4,Cnn2,Gadd45b,Rapgef5,B4galt4,Jun,Rbms1,Ldlr,Gbp2b,Lrrc8c,Filip1l,Itpkc,Irf1,Lyn,Adrb2,Tlr2,Cnn3,Zfp36,Slpi,Usp12,Rnf19a,Met,Eno2 |
| 9.550e-13 | -27.68 | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 402 | 76 | 15632 | 1249 |
Rgs3,Irak3,Tnfaip3,Rnf34,Cd74,Hif1a,Socs1,Lif,Rhoh,Mdm2,Errfi1,Dhx58,Rffl,Cish,Dusp8,Rgs14,Itpr1,Bcl6,Hsph1,Src,Dusp1,Plaur,Il1b,Thbs1,Grina,Ptprj,Zc3h12a,Uchl1,Dusp5,G3bp2,Sh3bp4,Nfkbid,Ddit4,Flrt2,Plek,Myadm,Dusp6,Atp2b4,Spred1,Dusp14,Pde3b,Prnp,Mul1,Nlrp3,Atf3,Cdkn2d,Optn,Phlpp1,Dusp4,Spry2,Myc,Dusp2,Psmd10,Dnaja1,Ptpn2,Ezr,Nfkbia,Sod2,Flrt3,Igf1r,Dusp16,Socs7,Tnip1,Aida,Tnip3,Lyn,Socs3,Mmp9,Stat1,Sirt1,Nfkbib,Cav1,Il10,Casp8,Rabgef1,Atm |
| 9.748e-13 | -27.66 | positive regulation of interleukin-1 beta production | biological process | GO:0032731 | 48 | 21 | 20694 | 1406 |
Jak2,Ifnar1,Ifi205,Aim2,Egr1,Ccl3,Ifi204,Tlr2,Hk1,Ripk2,Nod2,Nod1,Gsdmd,Malt1,Fzd5,Casp4,Ifi211,Mndal,Nlrp3,Casp1,Casp8 |
| 1.002e-12 | -27.63 | EINAV_INTERFERON_SIGNATURE_IN_CANCER | MSigDB lists | EINAV_INTERFERON_SIGNATURE_IN_CANCER | 24 | 16 | 15632 | 1249 |
Eif2ak2,Ifit1bl1,Morc3,Ifit1bl2,Ifit3,Ube2l6,Ifi44,Oas1a,Oas2,Ifi35,Oas1g,Stat1,Ifit3b,Isg15,Adar,Sp110 |
| 1.006e-12 | -27.63 | animal organ development | biological process | GO:0048513 | 3094 | 306 | 20694 | 1406 |
Klf2,Birc2,Triobp,Csrnp1,Ntng2,Spry2,Il15,Nupr1,Csf1,Myc,Fzd5,Ptpn2,Cebpd,Pdgfrb,Ppp4r2,Rac3,Kdm5b,Prkx,Etv6,Zeb1,Phactr4,Tulp3,Vegfc,Herc6,Azi2,Mecp2,Socs3,Ifna2,Tnc,Arid4a,Apobec3,Stat5a,Plagl1,Hopx,Pdpn,Apaf1,Slamf8,Slc9a1,Batf,Bbx,Ddit4,Tcea1,Crkl,Sphk1,Spint2,Errfi1,Jak2,Flrt3,Bcor,Tnfaip3,Inhba,Ripk3,Adar,Maff,Pou2f2,Mthfd1l,Tnfrsf1b,Akt3,Pdgfb,Lif,Slc25a25,Vcan,Arg2,Flt1,Heatr9,Batf2,Psma6,Nr3c1,Sema3c,Src,Stat3,Bcl2l11,H2-Ab1,Snx10,Odc1,Dock10,4932438A13Rik,Map2k1,Hcls1,Clic4,Vcam1,Tmem67,Cxcl14,Stxbp3,Ext1,Notch2,Zhx2,Calcrl,Egr1,Srgn,Fabp7,Bcl6,Plod3,Pdlim7,Slc4a7,Ednrb,Rcan1,Kdm6b,Agrn,Il12b,Col11a2,Cacybp,Sik3,Egr2,Kdr,P2ry12,Kitl,Ift57,H3f3b,Ifna6,Met,Serp1,Acvrl1,Casp8,Zfp513,Cdkn1a,Fcgr2b,Sdc4,Gys1,Pla2g4a,Arid5a,Casp3,Itgav,Dnaaf3,Gja1,Nfkb1,Relb,Cdk5r1,Rcn1,Nr4a3,Ccnd1,Mdm2,Btg2,Palld,Acp5,Pdgfc,Ifna1,Mapkapk2,Tet2,Fubp1,Hmga2,Ppp2r3a,Tal2,Nfkb2,Il6,Hif1a,Acvr1b,Sap30,Cflar,Jag1,Lox,Phgdh,Cnn2,Ttc39c,Cd34,Lhx2,Nrp2,Thbs1,Tnfsf9,Sema4a,Bmp2,Socs7,D16Ertd472e,Tent2,Sema4c,Homer1,Edn1,Stap1,Tsku,Flrt2,Papss2,Adap2,Serpine1,Fas,Lrp8,Gadd45g,Itga4,Irf4,Mmp14,Hivep3,Casp7,Clic5,Itgb8,Sav1,Ptger4,Mmp13,Hdac1,Irf1,Adgrg6,Adam19,Il10,Cx3cr1,Map2k4,Acvr1,Plaur,Intu,Nr4a1,Flnb,Tdrd7,Foxp4,Gsta3,Sbds,Tlr2,Hmox1,Clec4d,Clec4e,Gpr18,Sgcb,Tiparp,Cd300lf,Gfi1,Trip10,Prokr1,Notch1,Rhoh,Spred1,Htra1,Ifna5,Stk40,Ifna4,Hlx,Lrp4,Tmod3,Serpinb6b,Nos2,Tab2,Gpd2,B3gnt5,Csf3,Clec5a,Jarid2,Hap1,Tnfsf8,Rrs1,Ptprj,Fndc3a,Igf1r,Fgr,Tshz1,Ifnb1,Irs2,Jmjd6,Icam1,Insl6,Arid5b,Col27a1,Sec24b,Rpgrip1l,Junb,Malt1,Pou3f1,Cd74,Cited2,Syk,Pde3b,Rsad2,Fzd1,Jun,Sod2,Il1a,Ifi204,Tnf,Prdm1,Ikzf1,Angpt1,Ciapin1,Ccr1,Pml,Atf3,Eya4,Samd9l,Ptch1,Itpr1,Tmeff1,Htr2b,Lmo4,Slc7a11,Lyn,Cav1,Chst11,Clcf1,Pbx1,Ahr,Fam20c,Plcl2,Sirt1,Mmp9,Gpsm2,Irf8,Axl,Cd164,Hp,Hhex,Atm,Casz1,Bcl2a1d,Fos,Abr,Syne2,Bcl9,Ptgs2,Spn,Rapgef2,Timeless,Plscr1,Adgrl2 |
| 1.071e-12 | -27.56 | positive regulation of gene expression | biological process | GO:0010628 | 1992 | 216 | 20694 | 1406 |
Hif1a,Acvr1b,Kdm4a,Nfkb2,Il6,Jag1,Cnn2,Il2rg,Ciita,Prdm9,Thbs1,Lhx2,Bmp2,Rel,Ifnar1,Ikbkg,Gja1,Tlr3,Nr4a3,Relb,Nfkb1,Crlf3,Mdm2,Hmga2,Il1b,Polr2g,Tet2,Fubp1,Mapkapk2,Egr2,Nlrc5,Mdfic,Cx3cl1,Serp1,Myd88,Met,Acvrl1,Nck1,Zfp281,Arid5a,Etv5,Nampt,Rgcc,Egr1,Tra2a,Ppp1r15a,Agrn,Kdm6b,Ptafr,Mafg,Lif,Pdgfb,Wdr43,Stat3,Src,Egr3,Nr3c1,Map2k1,Hcls1,Eif4g2,Tfec,Stat2,Lcn2,Stat1,Jak2,Tlr6,Tcea1,Hmgn3,Ddx58,Adar,Maff,Inhba,Irf7,Pou2f2,Plac8,Optn,Nlrp3,Tnc,Arid4a,Mecp2,Plagl1,Ell2,Stat5a,Ccl2,Batf,Spic,Nfkbia,Tlr9,Adrb2,Pf4,Slc9a1,Med21,Ezr,Mllt6,Maml2,Rhoq,Csrnp1,Klf2,Ifrd1,Spen,Csf1,Aff1,Spry2,Plagl2,Cebpd,Dcp1a,Fzd5,Myc,Nr1h3,Fosb,Kdm5b,Zeb1,Etv6,Casz1,Klf6,Atm,Tent4a,Nfil3,Ahrr,Fos,Ier2,Bcl9,Fam129a,Plscr1,Cd38,Pik3cd,Hsph1,Ptch1,Lmo4,Helz2,Ahr,Pbx1,Tnip1,Ncoa7,Osm,Klf7,Cav1,Sirt1,Arf4,Hhex,Irf8,Lgals9,Bambi,Cited2,Stat4,Ccl3,Il1a,Daxx,Tnf,Fzd1,Tcf4,Pcgf5,Jun,Noct,Ikzf1,Prdm1,Pim2,Taf4b,Sertad3,Ago3,Pml,Atf3,Dr1,Wars,Phip,Igf1r,Larp1,Cd40,Psip1,Mycl,Ccl5,Serpinb9,Kat2b,Jmjd6,Ifnb1,Junb,Max,Cd74,Pou3f1,Rnf14,Parp9,Csf3,Hivep2,Tnfsf8,Ldlr,Tlr2,Pim1,Il18,Zc3h12a,Ythdf1,Notch1,Gfi1,Pid1,Ets2,Ptger4,Irf1,Adam19,Hdac1,Nr4a1,Irf2,Acvr1,Hinfp,Il10,Stap1,Edn1,Nsd3,Hmga1,Nod2,Serpine1,Zfp36,Irf4,Dtx3l,Med13,Hivep3,Itgb8,Mmp14 |
| 1.085e-12 | -27.55 | Tuberculosis | KEGG pathways | ko05152 | 177 | 48 | 7931 | 713 |
Fcgr2b,C3,Il1b,Il12b,Ripk2,Myd88,Jak2,H2-Ab1,Nod2,Ifna6,Tlr6,Casp3,Cycs,Cd14,Il18,Ifnb1,Ksr1,Tnf,Il10,Casp8,Tlr2,Cd74,Nos2,Ifna1,Sphk1,Apaf1,Ifna2,Tlr9,H2-Eb1,Ciita,Il6,Ifna4,Il1a,Irak2,Fcgr1,Plk3,Fcgr4,Tlr1,Malt1,Syk,Ifna5,H2-Aa,Rfx5,Clec4e,Src,Akt3,Nfkb1,Stat1 |
| 1.085e-12 | -27.55 | Tuberculosis | KEGG pathways | mmu05152 | 177 | 48 | 7931 | 713 |
Apaf1,Ifna2,Sphk1,Tlr9,Tlr2,Ifna1,Cd74,Nos2,Il10,Casp8,Ksr1,Tnf,Cd14,Il18,Ifnb1,Tlr6,Casp3,Cycs,Nod2,Ifna6,Fcgr2b,C3,Il1b,Il12b,Ripk2,H2-Ab1,Jak2,Myd88,Nfkb1,Stat1,Akt3,Src,Rfx5,H2-Aa,Clec4e,Malt1,Syk,Ifna5,Tlr1,Fcgr1,Irak2,Plk3,Fcgr4,H2-Eb1,Il6,Ciita,Il1a,Ifna4 |
| 1.119e-12 | -27.52 | movement of cell or subcellular component | biological process | GO:0006928 | 1356 | 161 | 20694 | 1406 |
Met,Acvrl1,Gpr35,Kif9,Pstpip2,Ift57,Nck1,Sdc4,Abcc1,Ccl12,Rasgrp1,Katna1,Spata13,Ccr1,Pml,Kdr,Bambi,Egr2,Ccl4,Syk,Ccl3,Tnf,Cx3cl1,P2ry12,Cacna1d,Inpp5b,Kitl,Actb,Ednrb,Insl6,Ift22,Arid5b,Fscn1,Pde4b,Il1rn,Agrn,Il12b,Mark2,Vcam1,Dync1h1,Cxcl14,Nox1,Ext1,Fut8,Icam1,Cxcl2,Ccl5,Uchl1,Trem1,Spn,Cd34,Lhx2,Rapgef2,Thbs1,Nrp2,Pik3cd,Sema4a,Hif1a,Cyfip1,Ap3m2,Ddx4,Lox,Saa3,Ier2,Vasp,Syne2,Palld,Ccl22,Arf4,Il1b,Axl,Asap3,Rhof,Htr2b,Gja1,Itgav,Ptch1,Plat,Cdk5r1,Nr4a3,Sdc1,Cxcl11,Sell,Klf7,Plau,Ccl2,Evl,Pf4,Slamf8,Sdc2,Acvr1,Ddit4,Nr4a1,Rab21,S100a8,Cx3cr1,Kif3c,Kif5c,Cenpe,Phactr4,Atp2b4,Mcoln2,Ccl7,Ap3b1,Pdpn,Cxcl1,Tspo,Pdgfrb,Myo10,Itga4,Ccl8,Ccr3,Ch25h,Prkx,Rac3,Ccl9,Rhoc,Prag1,Itgb8,Mmp14,Ptk2,Dync1i2,Sema4c,Ccrl2,Ntng2,Csf3r,Dnaja1,Stau1,Socs7,Ktn1,Dock4,Lrp8,Flrt2,Frmd6,Carmil1,Src,Myo1b,Egr3,Sema3c,Map2k1,Xcr1,Pvr,Hap1,Kcnj2,Vcan,Flt1,Cxcl10,Pdgfb,Cxcl9,Scn1b,Dst,Gpc1,Lpar1,Itga9,Notch1,Sele,Flrt3,Crkl,Cxcl3,Sbds,Tnfaip3 |
| 1.124e-12 | -27.51 | GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | MSigDB lists | GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 699 | 111 | 15632 | 1249 |
Lmo4,Sema3c,Cav1,Csf1,Syne2,Mmp9,Itga5,Ptk2,Sema4c,Lyn,Trib1,Lpar1,Ccl4,Rap2c,Jak2,Itgav,Cited2,Mmp14,Stap1,Col18a1,Evl,Cx3cl1,Irs2,F10,Sdc4,Myadm,Ccl5,Ccr1,Pde4b,Pdgfrb,Serpine1,Cd274,Flrt2,Nrp2,Spint2,Ppp2r3a,Cxcl2,Rapgef2,Hmox1,Gcnt2,Kitl,Cxcl1,Il1b,Tnf,Stat5a,Bcl6,Stat3,Dock10,Glipr2,Cd74,Sgk3,Pdgfc,Dach1,Rabgef1,P2ry2,Tnfsf14,Met,Jag1,Pla2g7,Sema4a,Pik3cd,Acvr1b,Kdr,Igf1r,Ccl12,Flt1,Cx3cr1,Jun,Dock4,Prkce,Il6,Pdpn,Edn1,Kcnj2,Cxcl14,Abr,Plau,Rras2,Angpt1,Tnfrsf14,Pdgfb,Hap1,Zc3h12a,Ptger4,Ptprj,Cxcl10,Ptafr,Ptgs2,Thbs1,Clic4,Prkx,Cmklr1,Pf4,Vegfc,Src,Swap70,P2ry12,Timp1,Rffl,Acvrl1,Acvr1,Itga4,Fgr,Sphk1,Spata13,Hif1a,Icam1,Ddx58,Bmp2,Notch1,Ripk3 |
| 1.130e-12 | -27.51 | GSE17721_CTRL_VS_PAM3CSK4_4H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_4H_BMDC_DN | 182 | 46 | 15632 | 1249 |
Frmd6,Fscn1,Cflar,Mafg,Mtdh,Mtmr14,Ebi3,Socs3,Ell2,Dtx2,Ksr1,Bcl9,Flnb,Lmo4,Nfkb1,Ahr,Olr1,Ccnd2,Stxbp1,Vcan,Cox17,Parp14,Igsf6,Mrpl52,D16Ertd472e,Cited2,Klf3,Sqstm1,Cldnd1,Chic2,Hp,Rab10,Igsf8,Igsf9,Nampt,Txn1,Plagl2,Upp1,Fabp3,Psma6,Slc39a4,Ttc39c,Hspa1a,Stat5a,Plekha5,Gypc |
| 1.211e-12 | -27.44 | GSE17721_LPS_VS_PAM3CSK4_24H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_24H_BMDC_UP | 189 | 47 | 15632 | 1249 |
Tifa,Procr,Stat4,Psmb8,Irf8,Il10,Arf4,Polr2g,Ap3m2,Ifi35,Aida,Irf1,Dnajb4,Parp9,Gadd45g,Rnf114,Spsb1,Gadd45b,Slamf7,F10,Olr1,Slc28a2,Dusp14,Noc4l,Parp12,Tyk2,Snx2,Gdf15,Junb,Samsn1,Atp10a,Ptgs2,1110038F14Rik,Ccng2,Tlk2,Clmp,Ifnar1,Casp1,Ddhd1,Stat5a,Hsph1,Tpst1,Cd83,Mdfic,Daxx,Psme1,Fam133b |
| 1.216e-12 | -27.44 | NF-kappa B signaling pathway | KEGG pathways | ko04064 | 98 | 34 | 7931 | 713 |
Myd88,Nfkb2,Ikbkg,Vcam1,Il1b,Lyn,Icam1,Tab2,Cflar,Tnfaip3,Bcl2a1b,Relb,Plau,Birc3,Tnfsf14,Cd14,Nfkbia,Birc2,Traf1,Ptgs2,Syk,Tnf,Malt1,Traf2,Traf5,Bcl2a1d,Ccl4,Cxcl2,Bcl2a1a,Cd40,Ddx58,Nfkb1,Gadd45b,Atm |
| 1.216e-12 | -27.44 | NF-kappa B signaling pathway | KEGG pathways | mmu04064 | 98 | 34 | 7931 | 713 |
Vcam1,Ikbkg,Nfkb2,Myd88,Tab2,Icam1,Lyn,Il1b,Tnfsf14,Birc3,Cd14,Plau,Relb,Cflar,Bcl2a1b,Tnfaip3,Traf5,Bcl2a1d,Traf2,Ccl4,Cxcl2,Traf1,Birc2,Nfkbia,Malt1,Syk,Tnf,Ptgs2,Atm,Gadd45b,Nfkb1,Cd40,Ddx58,Bcl2a1a |
| 1.243e-12 | -27.41 | CHICAS_RB1_TARGETS_CONFLUENT | MSigDB lists | CHICAS_RB1_TARGETS_CONFLUENT | 502 | 88 | 15632 | 1249 |
Tmem176a,Xaf1,Ifi211,Cnn3,Trim14,Mndal,Sema3c,Cav1,Jdp2,Adam19,Notch2,Mthfd2,Ifi204,Uaca,Itga5,Pde5a,Parp9,Optn,Hmga1,Ass1,Cnn2,Olr1,Klf7,Ifi207,Tspo,Gpc1,Sdc4,Ifi214,Arl4a,Palld,Evl,Ddx60,Sh3bp4,Pdlim7,Serpine1,Asns,Snn,Vcam1,Mcm6,Arid5b,Dock10,Errfi1,Phgdh,Ifi209,Mtus1,Ifit2,Mvp,Olfml3,Nupr1,Ifi203,Hivep3,Jag1,Ptch1,Ltbp2,Psat1,Actb,Cd200,Tnfsf4,Samd9l,Tmem171,Zyx,Tmem200b,Tagln,Atp2b4,Rras2,Tmtc2,Sgms2,Wars,Nmi,Slc7a5,Ifi208,Txn1,Thbs1,Osbpl3,Lox,C1ra,Dennd1b,Carhsp1,Ifi205,Psmb9,Apobec3,Ifi213,Axl,Ehd1,Gbp2,Dtx3l,Hhex,Itga4 |
| 1.286e-12 | -27.38 | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN | 176 | 45 | 15632 | 1249 |
Fgl2,Klf6,Cd302,P2ry13,Cd14,Pdgfc,Hck,Fgr,Sell,Tlr1,Spint2,Slc31a2,Ccr1,Rgl1,Thbs1,Acp2,St3gal1,Hmox1,Slamf8,Spry2,Gpr35,Rin2,Aoah,Ccl12,Syk,Fos,Cited2,Pilra,Clec4e,Tnfrsf14,Samhd1,Evl,Pstpip2,Ccrl2,Kctd12,S100a8,Ltbp2,Marco,Casp8,Adap2,Ccl4,Ppfibp2,Cdkn1a,Dram1,Tlr2 |
| 1.297e-12 | -27.37 | GO_REGULATION_OF_HEMOPOIESIS | MSigDB lists | GO_REGULATION_OF_HEMOPOIESIS | 296 | 62 | 15632 | 1249 |
Cd80,Il15,Il27,Tmem176b,Fas,Nlrp3,Il4ra,Ubash3b,Mmp14,Myc,Il6,Irf4,Ifnb1,Ap3b1,Syk,Eif2ak2,Nfkbia,Ptpn2,Jun,Fos,Hcls1,Egr3,Tnfsf4,Lyn,Trib1,Acvr1b,Irf1,Csf1,Zeb1,Rasgrp1,Tmem176a,Jag1,Casp8,Cd83,Notch1,Lif,Prdm1,Hlx,Isg15,Hif1a,Cd74,Pnp2,Gpr68,Tnf,Axl,Csf3r,Bcl6,Kitl,Il1b,Pf4,Ripk2,Tlr3,Il12b,Nfkbid,Inhba,Il12rb1,Csf3,Ccl5,Ccr1,Irf7,Pik3r6,Cd86 |
| 1.298e-12 | -27.37 | regulation of viral life cycle | biological process | GO:1903900 | 145 | 37 | 20694 | 1406 |
Shfl,Rsad2,Oasl2,Oasl1,Tnf,Fam111a,Eif2ak2,Slpi,Apobec3,Oas1a,Isg20,Trim56,Pml,Parp10,Trim26,Plscr1,Oas3,Pcx,Oas1g,Ifnb1,Trim30a,Adar,Ccl5,Stau1,Larp1,Trim21,Resf1,Trim13,Zc3hav1,Cd74,Oas1b,Chmp4b,Notch1,Nectin2,Isg15,Ifitm1,Zc3h12a |
| 1.343e-12 | -27.34 | BLALOCK_ALZHEIMERS_DISEASE_UP | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_UP | 1529 | 198 | 15632 | 1249 |
Nrp2,Trim26,Brd2,Slc12a9,Atp6v1d,Ppp1r15a,Sec24a,Inpp1,Vcam1,Sp110,Crkl,Il2rg,Trib3,Rnf24,Itgb8,Tnc,Arhgap26,Hdac1,Bcl6,Lipg,Tnfaip3,Asap3,Ch25h,Arg2,Tulp3,Med13,Csf1,Nfkb1,Gem,Cep350,Mndal,Plod2,Sema3c,Ldlr,Vrk2,H3f3b,Max,Sema4c,Vcan,Ifrd1,Sod2,Dhrs9,Eif2ak2,D16Ertd472e,Il15,Tle3,Ifi207,Col18a1,Nck1,Irs2,Ifi214,Slc7a5,Tlr1,Ifi208,Btg2,Tyk2,Maff,Cd86,Tnfsf10,Prkx,Snapc1,Tfec,Dcbld2,Smox,Pim1,Top3a,Rhoq,C1ra,Lrp4,Ifi213,Ifi205,Pml,Sell,Jmjd6,Sphk1,Icam1,Timeless,Igf1r,Il13ra1,Itpkc,Socs3,Mafg,Acsl1,Acvr1b,Il6,Pdpn,Nqo1,Triobp,Nfkbia,Jun,Tiparp,Gclc,Mapkapk2,Sap30,Psd4,Gja1,Pdgfrb,Irf7,Golga3,Ralgds,Kitl,Cxcl1,Hmox1,Nr4a3,Il18,Cdc42ep4,Osgin2,Cp,Rbpms,Plod3,Plekha5,Ifi209,Mgat1,Mtus1,Sav1,Plagl2,Stau1,Zfp36,Spen,Ifi211,Trim14,Ust,Ppp2r1b,Rbms1,Hsd17b7,Dnajb2,Ppfibp2,Oasl1,Ifi204,Odc1,Mid1,Pcx,Gadd45g,Ppp1r14b,Spsb1,Gadd45b,Trip10,Tspo,Pilra,Rbl1,Zc3hav1,Klf7,Aff1,Palld,Tpi1,Kat2b,Pdgfb,Slc4a7,Nampt,Arid4a,Dmwd,Klf2,Rnaset2a,Daam1,Cnp,Gng12,Vegfc,Casp3,Cebpd,Tapbp,N4bp1,Ehd1,Slc2a1,Birc2,Dse,Bfar,Gbp2,Myo10,Cd164,Malt1,Ier2,Slco3a1,Sertad3,Il1a,Ep400,Ampd3,Pdss1,Akt3,Dcp1a,Ifi203,Met,Rnf19a,Ltbp2,Ptch1,Casp4,Tnip1,Cflar,Armc8,Rnaset2b,Igsf6,Tagln,Trmt1l,Agrn,Pfkfb3,Rbms2,Tap1,Angpt1,Plagl1 |
| 1.395e-12 | -27.30 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_UP | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_UP | 183 | 46 | 15632 | 1249 |
Ifi211,Trim14,Tifa,Ube2e2,Ifi203,Kctd12,Xaf1,Psmb8,Irf8,Mndal,Rnaset2b,Lrrc8c,Stat1,Ifi204,Pdzd11,Myc,Parp9,Srm,Ccl12,Spred1,Hk3,Ifi207,Evl,Rtp4,Ifi214,Ifi208,Uba7,Ccr1,Slc7a8,Ccl5,Rnaset2a,Il1rn,Sp110,Slc43a3,Slamf8,Mdn1,Batf2,Egr2,Ccdc86,Atp13a1,Ifi213,Homer1,Ifi205,Ifi209,Ch25h,Trim12c |
| 1.395e-12 | -27.30 | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN | 183 | 46 | 15632 | 1249 |
Ppfibp2,Cdkn1a,Mmp9,Acsl1,Rab20,St3gal5,Pla2g7,Mmd,Kctd12,Irf8,Sema3c,Marco,Plau,Tmem176b,Ccl22,Nlrp3,Slc30a1,Ctsc,Fcgr2b,Sqstm1,Ccl12,Syk,Cyfip1,Fos,Cmklr1,Plaur,Rtn1,Il18,Tlr1,Slc2a6,Snx2,Maff,Rgl1,Serpine1,Cd14,Pdgfc,Hck,Hlx,Kmo,Sat1,Slc15a3,Rhoq,Fgl2,P2ry13,Tcf4,Rhbdf2 |
| 1.395e-12 | -27.30 | GSE29618_PDC_VS_MDC_DN | MSigDB lists | GSE29618_PDC_VS_MDC_DN | 183 | 46 | 15632 | 1249 |
Cd86,Nampt,Junb,Hk2,Stx11,Ptgs2,Rtn1,H2-Ab1,Ptger4,Bcl2a1a,Il1rn,Oas3,Eno1,Bcl6,P2ry13,Timp1,Casp1,Cebpd,Bcl2a1d,Fgl2,Ly75,Fgr,Slco3a1,Hif1a,Hck,Gbp2,Irak3,Apaf1,Pid1,Xaf1,Pstpip2,Trib1,Il13ra1,Ppa1,Tnfaip2,Tiparp,Cyfip1,Bcl2a1b,Aoah,Rab32,Cnn2,Nod2,Evl,Ahr,Pilra,Ciita |
| 1.395e-12 | -27.30 | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | MSigDB lists | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | 183 | 46 | 15632 | 1249 |
Rhoq,Rnf24,B3gnt5,Tlk2,Mafk,Dusp1,Birc2,Swap70,Cd83,Relb,Csrnp1,Slc7a5,Caml,Pdgfb,Plek,Hmox1,Pcgf5,Fam53c,Usp31,Cxcl10,4930453N24Rik,Ifrd1,Cnot4,Cox17,Nr4a1,Trip10,Lrp8,Cyth3,Zeb1,Il18rap,Birc3,Ankib1,Casp4,Tax1bp1,Tnip1,Asf1a,Gfpt1,Arf4,Rbms1,Nfil3,Abcc1,Socs7,Ell2,Azi2,Rab20,Itga9 |
| 1.409e-12 | -27.29 | BOYLAN_MULTIPLE_MYELOMA_PCA1_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA1_UP | 97 | 32 | 15632 | 1249 |
Ifi209,Ifi205,Ifi213,Fgl2,Cp,Igsf6,Ifi214,Ifi207,Zbp1,Itgal,Mndal,Lcn2,Hdc,S100a8,Ccl5,Stat4,Ifi203,Tmem176a,Isg20,Ifi211,Ifi208,Plscr1,Ifi204,Tgfbi,Fpr1,Hp,Mmp9,Ell2,C3,Tfec,Osbpl3,Fscn1 |
| 1.421e-12 | -27.28 | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | 120 | 36 | 15632 | 1249 |
Ripk2,Tnfsf4,Egr3,Il12b,Trib1,Hcls1,Kitl,Pf4,Il1b,Ccl5,Ccr1,Pik3r6,Casp8,Cd86,Csf1,Rasgrp1,Il12rb1,Lif,Prdm1,Hlx,Il4ra,Nlrp3,Cd74,Cd80,Il15,Cd83,Syk,Tnf,Axl,Jun,Fos,Il6,Pnp2,Mmp14,Gpr68,Ap3b1 |
| 1.466e-12 | -27.25 | protein modification process | biological process | GO:0036211 | 2396 | 249 | 20694 | 1406 |
St3gal5,Btg2,Mdm2,Mlkl,Extl2,Tmtc2,Acp2,Dtx2,Il1b,Ppp2r3a,Isg15,Sla,Pim3,Trib3,Mppe1,Tet2,Mapkapk2,Itgav,Tlr3,Ccnd1,Keap1,Prkce,Cdk5r1,Ppp2r5a,Ppm1l,Fbxo4,Thbs1,Plk2,Grk3,Ube2l6,Prdm9,Bmp2,Ubr4,Ccnd2,Acvr1b,Dusp1,Pgap2,Kdm4a,Dusp8,Saa3,Lox,Otud1,Sap30,Ppp1r15a,Plod3,Dusp4,Kdm6b,Cnot4,Plod2,Mark2,Ext1,Ube2e2,Kmt5a,Fut8,Acvrl1,Myd88,Serp1,Met,Nck1,Rnf19a,Uba7,Trim56,Kdr,Setdb2,Dusp6,Egr2,Sik3,Phlpp2,Gfpt1,Ubash3b,Mdfic,Rffl,Spsb1,Rnf139,Ranbp2,Akt3,Usp35,Bcor,Jak2,Hat1,Sphk1,Tyk2,Ripk3,Trib1,Tnfaip3,Il12rb1,Rictor,Peli1,Parp12,Hck,Src,Trim12c,Pdk3,Map2k1,Tpst1,Flt1,Usp12,P4ha2,Lif,Pdgfb,Ikbke,Dpy19l1,Ube2e1,Pdgfrb,Ptpn2,Myc,Prag1,Prkx,Kdm5b,Rnf19b,Ppp4r2,Ptk2,Dusp16,Birc2,Dusp14,Ifih1,Nupr1,Il15,Ccng2,Med21,Parp8,Tlr9,Arrdc4,St3gal1,Scyl2,Birc3,Parp14,Rnf34,Znrf3,Arid4a,Mecp2,Usp31,Dcun1d3,Herc6,Hopx,Eif2ak2,Ppm1k,Map3k8,Stat5a,Trim12a,Sirt1,Arf4,Arel1,Fam20c,Trim13,Axl,Htr2b,Usp18,Trim30a,Parp11,Lyn,St3gal3,Osm,Cdyl,Sde2,Dusp5,Ppp2r2a,Dusp2,Atm,Ankib1,Mgat1,Mmd,Ksr1,Malt1,P4ha1,Rnf31,Dusp28,Parp3,Dr1,Fgr,Vrk2,Map3k6,Igf1r,Ccl5,Hk1,Uchl1,Jmjd6,Kat2b,Bfar,Eya4,Ccl12,Ccnj,Pim2,St3gal6,Parp10,Pml,Rnf135,Stat4,Syk,Mapkbp1,Tnf,Plk3,Trim36,Pcgf5,Zc3h12a,Il18,Tiparp,Irak2,Crbn,Znrf1,Vcpip1,Usp53,Pim1,Tlr2,Plpp1,Gcnt2,Dyrk2,B3gnt5,Map4k4,Ptprj,Tlk2,Ccne1,Jarid2,Traf2,Usp25,Nek6,Rnf14,Nos2,Ripk2,Parp9,Mul1,Irgm2,Stk40,Irf4,Ep400,Zfp36,Dtx3l,Irak3,Ccr3,Mtmr14,Cop1,Morc3,Sgk3,Trim21,Socs7,Nsd3,Ube2f,Klhl25,Pigv,Phlpp1,Hdac1,Ppp1r15b,Acvr1,Map2k4,S100a8,Usp42,Ptger4,Naa25,Egln3 |
| 1.466e-12 | -27.25 | cellular protein modification process | biological process | GO:0006464 | 2396 | 249 | 20694 | 1406 |
Rffl,Mdfic,Ubash3b,Phlpp2,Gfpt1,Sik3,Kdr,Setdb2,Egr2,Dusp6,Trim56,Uba7,Rnf19a,Nck1,Met,Myd88,Serp1,Acvrl1,Fut8,Kmt5a,Ube2e2,Ext1,Mark2,Plod2,Cnot4,Kdm6b,Dusp4,Plod3,Ppp1r15a,Sap30,Otud1,Lox,Dusp8,Saa3,Kdm4a,Pgap2,Dusp1,Acvr1b,Ccnd2,Ubr4,Bmp2,Prdm9,Ube2l6,Grk3,Plk2,Thbs1,Fbxo4,Ppm1l,Ppp2r5a,Cdk5r1,Prkce,Keap1,Ccnd1,Tlr3,Itgav,Mapkapk2,Tet2,Mppe1,Trib3,Ppp2r3a,Pim3,Sla,Isg15,Acp2,Dtx2,Il1b,Tmtc2,Extl2,Mdm2,Mlkl,St3gal5,Btg2,Stat5a,Trim12a,Map3k8,Ppm1k,Eif2ak2,Hopx,Dcun1d3,Herc6,Usp31,Mecp2,Arid4a,Znrf3,Rnf34,Parp14,Birc3,Scyl2,St3gal1,Tlr9,Arrdc4,Parp8,Med21,Ccng2,Il15,Nupr1,Ifih1,Dusp14,Birc2,Dusp16,Ptk2,Rnf19b,Ppp4r2,Kdm5b,Prkx,Prag1,Myc,Ptpn2,Pdgfrb,Ube2e1,Dpy19l1,Ikbke,Pdgfb,Lif,P4ha2,Flt1,Usp12,Tpst1,Map2k1,Trim12c,Pdk3,Src,Hck,Parp12,Peli1,Rictor,Il12rb1,Trib1,Tnfaip3,Ripk3,Tyk2,Hat1,Sphk1,Jak2,Bcor,Usp35,Akt3,Ranbp2,Rnf139,Spsb1,Trim36,Pcgf5,Mapkbp1,Tnf,Plk3,Syk,Rnf135,Stat4,Pml,Parp10,Pim2,St3gal6,Ccl12,Ccnj,Eya4,Bfar,Jmjd6,Kat2b,Uchl1,Hk1,Ccl5,Igf1r,Map3k6,Vrk2,Fgr,Dr1,Dusp28,Parp3,Rnf31,P4ha1,Malt1,Ksr1,Mmd,Mgat1,Ankib1,Atm,Ppp2r2a,Dusp2,Sde2,Cdyl,Dusp5,Osm,St3gal3,Lyn,Parp11,Trim30a,Usp18,Htr2b,Axl,Trim13,Fam20c,Arf4,Arel1,Sirt1,Egln3,Naa25,Ptger4,Usp42,S100a8,Map2k4,Acvr1,Ppp1r15b,Phlpp1,Hdac1,Pigv,Klhl25,Ube2f,Nsd3,Socs7,Trim21,Sgk3,Cop1,Morc3,Mtmr14,Ccr3,Dtx3l,Irak3,Zfp36,Irf4,Ep400,Stk40,Irgm2,Parp9,Ripk2,Mul1,Nos2,Rnf14,Nek6,Usp25,Traf2,Jarid2,Ccne1,Tlk2,Ptprj,Map4k4,B3gnt5,Dyrk2,Gcnt2,Plpp1,Tlr2,Usp53,Pim1,Vcpip1,Znrf1,Crbn,Irak2,Tiparp,Il18,Zc3h12a |
| 1.474e-12 | -27.24 | MARSON_BOUND_BY_FOXP3_STIMULATED | MSigDB lists | MARSON_BOUND_BY_FOXP3_STIMULATED | 920 | 135 | 15632 | 1249 |
Zbtb5,Ifi207,Zc3hav1,Me1,Rbl1,Tle3,Kat2b,Pikfyve,Ifi214,Nr1h3,Tor1aip2,Ctsc,Stap1,Aftph,Cept1,Cpd,Gadd45b,Dhrs9,Gpr18,Cited2,Orai2,Gfpt1,Lrrc25,Jak2,Fam162a,Frmd6,Dnajb4,Tnip3,Ifi204,Ifi211,Srxn1,Csf1,Atm,Dcun1d3,Tnfrsf1b,Rel,Mndal,Apaf1,Rgs3,Parp10,Csrnp1,Prrg4,Zfp281,Fam133b,Tab2,Arg2,Oaf,Stat3,Cdyl2,Fgl2,Ccng2,Klf6,Ifi209,Gtpbp2,Rcl1,Pgk1,Acp2,Arid5b,Ddit4,Arl5b,Slc25a12,Fam72a,Ccr1,Dusp6,Lcp2,Cd274,Tor1aip1,Slfn4,Prdx1,Chmp4b,Etv3,Ccr3,Gpr35,Myc,Ppp2r5a,Fam43a,Cx3cr1,Tiparp,Asf1a,Rgs1,Hcls1,Armc8,Kpna3,Tnfsf4,Tmod3,Ms4a6d,Sema4a,Ier3,Mefv,Gpd2,Ifi203,Birc3,Lnpep,Irf8,Itgal,Tnfsf14,Smg7,Irf2,Rab19,Jmjd6,Fgr,Dennd1b,Cish,Egr2,Kdm5b,Mdm2,Gsr,Ifi213,Hsph1,Gypc,Ifi205,Slc2a1,Slfn3,Slc37a3,Ptger4,Ptprj,Dnaja2,Kcna3,Pim1,Chic2,Cxcl10,Rilpl1,Wdr59,Ifi208,Nfkbid,Adora2a,Dgka,Txn1,Junb,Map4k4,Tshz1,Samsn1,Igsf8,Fubp1,Sipa1l1 |
| 1.554e-12 | -27.19 | positive regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043123 | 112 | 32 | 20694 | 1406 |
Tlr6,Ikbkg,Mtdh,Ankrd17,Tlr3,Traf5,Prkce,Nod2,Nod1,Rnf31,Clec4n,Traf3ip2,Il1b,Il1rn,Zc3hav1,Trim13,Cd74,Traf2,Cx3cl1,Tnf,Tab2,Il1a,Tifa,Ripk2,Peli1,Myd88,Tnfsf10,Tlr9,Pim2,Cx3cr1,Casp1,Casp8 |
| 1.563e-12 | -27.18 | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN | 197 | 48 | 15632 | 1249 |
Dmxl2,Plagl1,Pilra,Syk,Rab32,Igsf6,Rin2,Nod2,Vcan,Mtmr14,Acsl1,Lyn,Sema4a,Tlr2,Ms4a6d,Tnfaip2,Notch2,Siglece,Tnfrsf1b,S100a8,Adap2,Irf8,Etv6,Kctd12,Fgr,Cd14,Irak3,Hck,Slc16a3,Csf3r,Mgat1,Bcl6,Slc15a3,Sat1,Cebpd,Fgl2,Arhgap26,Hmox1,Rtn1,Fpr1,Ptafr,Tgfbi,Gca,Dusp6,Ccr1,Slc31a2,Ext1,Wars |
| 1.582e-12 | -27.17 | response to toxic substance | biological process | GO:0009636 | 328 | 60 | 20694 | 1406 |
Slc30a4,Slc31a1,Sphk1,Gsta3,Casp3,Prdx5,Slc7a11,Nfkb1,Tnfaip3,Ripk3,Nr4a3,Prkce,Hmox1,Ahr,Sirt1,Zc3h12a,Axl,Hp,Pdgfb,Scn1b,Il6,Hif1a,Mt1,Timeless,Src,Lcn2,Ass1,Igf1r,Pde1b,Fas,Esd,Ccl5,Nupr1,Egr1,Bnip3,Pdgfrb,Nqo1,Actb,Kdm6b,Selenow,Abcb1a,Srxn1,Ccl4,Kdr,Sod2,Eif2ak2,Daxx,Ccl7,Adora2a,Tnf,Mt2,Slc30a1,Prdx1,Hdac1,Gk,Cnp,Casp8,S100a8,Abtb2,Ppp1r15b |
| 1.620e-12 | -27.15 | KIM_WT1_TARGETS_UP | MSigDB lists | KIM_WT1_TARGETS_UP | 204 | 49 | 15632 | 1249 |
Csf1,Zeb1,St3gal5,Slpi,Eno2,Nfkb1,Gem,Actb,Hmgcs1,Itpkc,Lpar1,Trib1,Ier3,Spry2,Rai14,Myc,Nr4a1,Nfkbia,Ccl12,Zyx,Hmga1,Rras2,Sdc4,Rnd3,Egr1,Il4ra,Cx3cl1,Phlpp2,Inhba,Maff,Junb,Serpine1,Pcdh7,Nfkb2,Thbs1,Plaur,St3gal1,Kdm6b,Dusp5,Arid5b,Nr3c1,Nfkbie,Cers6,Cd83,Relb,Tnfaip3,Ier2,Lif,Sphk1 |
| 1.625e-12 | -27.15 | GO_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | 76 | 28 | 15632 | 1249 |
Irf1,Ifi204,Tlr2,Tlr3,Tlr9,Ripk2,Nfkb2,Mndal,Irf7,Nfkb1,Ifi203,Ifi211,Ifi208,Ddx58,Ifi214,Ifih1,Rnf135,Ifi207,Zc3hav1,Myd88,Cd14,Zbp1,Ifi209,Ifi205,Ifi213,Ifnar1,Syk,Dhx58 |
| 1.644e-12 | -27.13 | homeostatic process | biological process | GO:0042592 | 1625 | 184 | 20694 | 1406 |
Sesn3,Tmod3,Smc5,Tmem178,1600014C10Rik,Scn1b,Xcr1,Ccne1,Hap1,Smg7,Ldlr,Gcnt2,Hmox1,Gpr18,Marcksl1,Slc31a1,Notch1,Chmp4b,Il18,Ehd1,Tspo,Atp2b4,Ptger4,Hspa1a,Cmklr1,Cx3cr1,Gk,Nod2,Fas,Stau1,Homer1,Xrn1,Edn1,Ccr3,Ptgir,Med13,Slc12a9,Gclm,Rmdn3,Gna15,Atm,Dmxl2,Pik3cd,Cd38,Slc39a13,Slc7a11,Klf7,Lyn,Cav1,Slc31a2,Ahr,Itpr1,Ptch1,Htr2b,Slc39a4,Axl,Txnrd1,Grina,Sirt1,Sod2,Ccl3,Il1a,Cited2,Pde3b,Pml,Ccr1,Prdx1,Ikzf1,Rab20,Jmjd6,Slc16a1,Icam1,Hk1,Ccl5,Cxcl2,Igf1r,Atp13a1,Cd40,Cutc,Nox1,Parp3,Fabp3,Gclc,Pde4b,Lipg,Fpr1,Lpar1,Ero1l,Cxcl10,Mafg,Snx10,Lcn2,Fpr2,Map2k1,Dock10,Sec24a,Pdk3,Hcls1,Ampd3,Bcl2l11,Stat3,Bcl2a1a,Src,Cxcl3,Ncoa5,Tnfaip3,Ripk3,Adar,Tcea1,Stat1,Prdx5,Jak2,Akt3,Hk3,Swap70,Stat5a,Cxcl1,Arid4a,Mllt6,Glrx,Sco1,Adrb2,Tlr9,Slc30a1,Slc9a1,Slamf8,Ccl2,Gsr,Hcar2,Csf1,Klf2,Ccrl2,Ptk2,Nr1h3,Rac3,Htr2a,Vps54,Myc,Pdgfrb,Ptpn2,Lox,Il6,Hif1a,Cd34,Cacnb3,Mt1,Fbxo4,Prnp,Nr4a3,Prkce,Hk2,Slc30a4,Ikbkg,Gja1,Itgav,Casp3,Tet2,Pmaip1,Slc39a14,Tmtc2,Il1b,Ttc39b,Acp5,Cacna1d,P2ry2,Cx3cl1,Mt2,Col11a2,Kdr,Pla2g4a,Cp,Met,Gpr35,Egr1,Clic4,Vcam1,Stxbp3,Slc28a2,Txn1,Il1rn,Bnip3,Bcl6,Ednrb,Slc4a7 |
| 1.655e-12 | -27.13 | REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS | MSigDB lists | REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS | 66 | 26 | 15632 | 1249 |
Casp8,Irf7,Ikbkg,Uba7,Ifna6,Nfkbib,Ube2l6,Irf1,Tax1bp1,Ikbke,Nfkb2,Tank,Traf2,Nfkbia,Nlrc5,Ifnb1,Ifna5,Dhx58,Isg15,Rnf135,Ifih1,Ddx58,Irf2,Tnfaip3,Ifna2,Ifna1 |
| 1.665e-12 | -27.12 | NFKAPPAB_01 | MSigDB lists | NFKAPPAB_01 | 232 | 53 | 15632 | 1249 |
Mob3c,Rbms1,Tnip1,Rap2c,Irf1,Ebi3,Uaca,Mmp9,Zscan29,Etv6,Nfkbib,Tifa,Birc3,Tnfrsf1b,Plau,Sdc4,Il27,Zbtb5,Nod2,S1pr2,Rin2,Ifnb1,Cpd,Il4i1,Lrch1,Slc44a1,Gadd45b,5430427O19Rik,Vcam1,Cxcl1,Il1rn,Ralgds,Nfkb2,Slamf8,Cxcl10,Map3k8,Xkr8,Gng4,Nfkbid,Tnfsf15,Samsn1,Col11a2,Jarid2,Ccl5,Relb,Cd83,Il1a,Icam1,Rnd1,Zmynd15,Cd40,Parp8,Tnf |
| 1.683e-12 | -27.11 | negative regulation of transferase activity | biological process | GO:0051348 | 261 | 52 | 20694 | 1406 |
Pml,Cdkn1a,Nck1,Adora2a,Socs1,Dusp6,Ubash3b,Spred3,Gadd45b,Parp3,Zfp36,Ptpn2,Actb,Dusp4,Gadd45g,Aida,Irak3,Dtx3l,Cdkn2d,Kat2b,Irs2,Spry2,Uchl1,Dusp16,Wars,Dnaja1,Igf1r,Prkar2b,Dusp2,Ptprj,Src,Dusp5,Fam72a,Mvp,Dusp8,Dusp1,Spred1,Il6,Hhex,Rhoh,Il1b,Rgs14,Trib3,Sirt1,Adar,Tnfaip3,Lyn,Trib1,Cav1,Ppp2r5a,Errfi1,Casp3 |
| 1.719e-12 | -27.09 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN | 184 | 46 | 15632 | 1249 |
Fam111a,Kif5c,Ebi3,Dram1,Endod1,Zc3h12c,Tnfrsf1b,Il18rap,Rap1gap2,Mmd,Hivep3,Ccrl2,Plscr1,Ahr,Ppfibp1,Atp2b4,Cd80,Fbxo4,Cyfip1,Itgav,Bcl2a1b,Rin2,Chst11,Stap1,Ttc39b,Map3k8,Nsmaf,Cldnd1,Osbpl3,Bcl2a1a,Vps54,Hopx,Samsn1,Stx11,Phlda1,Icam1,Prdm1,Hhex,Cd38,Ttc39c,Bcl2a1d,Nfkbie,Itgb8,Slc15a3,Egr2,Casp3 |
| 1.719e-12 | -27.09 | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_DN | MSigDB lists | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_DN | 184 | 46 | 15632 | 1249 |
Nfkb1,Ankib1,Ifit3,Psme2,Trim21,Isg20,Cnn3,Hat1,Mtdh,Pik3cd,Map2k4,Mthfd2,Ifit3b,Irf1,Rcn1,Ldlr,Actb,Plac8,Irgm2,Gclm,Cox17,Ccnd2,Adar,Chmp4b,Snx10,Atp6v1d,Noc4l,Wars,Serpinb9,Tnfsf10,Parp8,Arhgef3,Rhoq,Pnp2,Rsad2,Hdac1,Itga4,Isg15,Ifih1,Sell,Gbp3,Agtrap,Usp18,Icam1,Gbp2,Ifit1 |
| 1.719e-12 | -27.09 | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_UP | MSigDB lists | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_UP | 184 | 46 | 15632 | 1249 |
Igsf6,S1pr2,Tra2a,Rab32,Cited2,Pilrb2,Pilra,Nek6,Nck1,Tmem176b,Tpx2,Xrn1,Fpr2,Trip13,Slpi,Spen,Clec4n,S100a8,Pdk3,Ifit3,Tnfaip2,Ifit3b,Gbp4,Gbp9,Phgdh,Hspa2,Insl6,Dusp1,Csf3r,Mtus1,Gnb4,Gbp2,Etv5,Gda,Plk3,Ifih1,Atp11a,Fam72a,Bst1,Txn1,Pilrb1,Vcam1,Il1b,Ldha,St7,Mcm6 |
| 1.719e-12 | -27.09 | GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_UP | MSigDB lists | GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_UP | 184 | 46 | 15632 | 1249 |
Ube2f,Plau,Gnb4,Lrp8,Plk3,Magohb,Prdm1,Traf1,Socs1,P2ry14,Ubtd2,Psma6,Errfi1,Cox17,Aebp2,Taf4b,Gadd45b,Src,Hsph1,Stat5a,Lipe,Homer1,Fam20c,Serpinb2,Cmklr1,Il1rn,Gfi1,Abcc1,Fmnl2,Ppa1,Fndc3a,Kdm6b,Gpr85,Odc1,Alas1,Slc2a6,Procr,Inpp5b,Cnn3,Met,Ccrl2,Slc31a2,Slc4a7,Rgl1,Fubp1,Lcp2 |
| 1.740e-12 | -27.08 | VILIMAS_NOTCH1_TARGETS_UP | MSigDB lists | VILIMAS_NOTCH1_TARGETS_UP | 52 | 23 | 15632 | 1249 |
Cd86,Irf7,Birc2,Nfkbia,Junb,Birc3,Bcl2a1b,Ccl5,Cd69,Bcl2a1d,Egr2,Icam1,Cd74,Il12b,Traf1,Cx3cl1,Egr1,Relb,Cd83,Bcl2a1a,Rras2,Cd80,Nfkb2 |
| 1.750e-12 | -27.07 | regulation of alpha-beta T cell activation | biological process | GO:0046634 | 106 | 31 | 20694 | 1406 |
Cd274,Cd83,Nlrp3,Il12b,Lgals9,Il18,Zc3h12a,Malt1,Bcl6,Il4ra,Tarm1,Nfkbid,Tnfrsf14,Nfkbiz,Tnfsf4,Irf1,Ikzf1,H2-Ab1,Il27,Prdm1,Hsph1,Adora2a,Ap3b1,Socs1,Il2rg,Ripk2,Hlx,Arg2,Syk,Cd80,Il6 |
| 1.758e-12 | -27.07 | side of membrane | cellular component | GO:0098552 | 608 | 90 | 20747 | 1409 |
Xcr1,Fas,Thbs1,Pdpn,Cd34,Sdc1,Fcgr1,Ly6a,Gramd1a,Vcam1,Antxr1,Birc2,Sell,Csf3r,Ebi3,Il12rb1,Dst,Cxcl10,P2ry12,Fgr,Adam19,Fcgr4,Cd83,Tlr2,Kdr,Clec2d,Icosl,Il6,Cd55,Hck,Cd40,Siglece,Lyn,Itga4,Traf2,Gna15,Klrk1,Ccr1,Il2rg,Tnf,Cd200r4,Fcgr2b,Ccrl2,Il13ra1,Traf5,Gnb4,H60b,Cd80,Errfi1,Cxcl9,Itgav,Gem,Ly75,Tmem123,Icam1,Tnfrsf14,H2-M2,Rab21,Gng4,H2-T10,Ezr,Cd69,H2-Ab1,Gsr,Src,Pkp4,Rgs1,Spn,Gng12,Itgal,Cd14,Cd274,Cx3cr1,H2-T24,Cd86,Ldlr,H2-Aa,H2-Q6,Cyth3,Raet1e,H2-T22,Gng11,H2-Q7,Itga5,Cd74,Slamf7,Chmp4b,Ccr3,Rnf31,H2-Q4 |
| 1.857e-12 | -27.01 | GO_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_APOPTOTIC_SIGNALING_PATHWAY | 276 | 59 | 15632 | 1249 |
Ifi203,Casp2,Sirt1,Ifi211,Casp4,Mndal,Casp8,Cav1,Tnfrsf1b,Atm,Cdkn1a,Jak2,Acvr1b,Ifi204,Dyrk2,Uaca,Bnip3,Ggct,Jun,Itgav,Sod2,Bcl2a1b,Bcl2l11,Spn,Ifi207,Tnfrsf14,Ifi214,Fas,Inhba,Ifi208,Ddit4,Ppp1r15a,Il1b,Ikbke,Kitl,Tnfsf10,Bcl2a1a,Trib3,Hmox1,Tlr3,Bcl2a1d,Cycs,Casp3,Ifi209,Cd40,Ifi205,Traf2,Itpr1,Tnf,Ifi213,Ripk3,Apaf1,Cd38,Daxx,Tnfrsf8,Cd14,Il1a,Pml,Nupr1 |
| 1.866e-12 | -27.01 | GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 979 | 141 | 15632 | 1249 |
Pml,Rhoh,Hhex,Nfkbil1,Itga4,Ube2e1,Psme1,Socs1,Crim1,Notch1,Cst7,Src,Ifi213,Dusp1,Birc2,Ifi205,Psmb9,Timp1,Rgs14,Rffl,Cish,Dusp8,Rab9,Casp3,Psma6,Mdm2,Uchl1,Dusp5,Zc3h12a,Ptprj,Serpinb9,Pim1,Serpinb2,Thbs1,Cmklr1,Plaur,Ifit1bl2,Ifi208,Pdgfb,Nfkbid,Nlrp3,Prnp,Pttg1,Adar,Atp2b4,Flrt3,Nlrc5,Ifit1bl1,Nfkbia,Jun,Psmd10,Peli1,Il6,Ppp2r5a,Prkce,Spry2,Nqo1,Socs3,Tnfsf4,Adrb2,Aida,Prkar2b,Socs7,Gfi1,Igf1r,Birc3,Psmb8,Ptch1,Tnfsf14,Il10,Ifi203,Sirt1,Aim2,Parp10,Psmb10,F11r,Pbx1,Rnf34,Irak3,Tnfaip3,Mvp,Rgs3,Tnf,Ifit2,P2ry13,Ifi209,Prdx5,Errfi1,Psmb6,Hmox1,Hp,Trib3,Irak2,Mitd1,Keap1,Il1b,Dusp6,Serpine1,Ppp1r15a,Flrt2,Spint2,Sh3bp4,Cdkn2d,Nck1,Ifi214,Irs2,Ubash3b,Kat2b,Dusp14,Zc3hav1,Ifi207,Spred1,Ppp1r14b,Gadd45b,Dnaja1,Ptpn2,Nlrc4,Dusp2,Dusp4,Mmp9,C3,Tlr9,Lyn,Ifi204,Trib1,Tax1bp1,Jak2,Cdkn1a,Lhx2,Dusp16,Nfkb1,Ednrb,Mndal,Casp8,Cav1,Psme2,Slpi,Med13,Cnn3,Trim21,Ifi211 |
| 1.962e-12 | -26.96 | GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_UP | MSigDB lists | GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_UP | 152 | 41 | 15632 | 1249 |
Rbpms,Pnp2,Egr2,Rnf24,Kcnj2,Pla2g4a,Cd302,Psmd10,Casp1,Gsdmd,Lipe,Daxx,Cd14,Ciita,Fbrsl1,Traf1,Ifih1,Cd74,Usp18,Nupr1,Stxbp1,Tmem176b,Nfkbiz,Pgs1,Tmem176a,Tbc1d13,Parp12,Bst1,Mmd,Slc2a6,Nrp2,Btg2,Golga3,Plekha2,Epsti1,Tnfsf10,Tnip1,Fpr1,Atp10a,Dram1,Ebi3 |
| 2.055e-12 | -26.91 | KUMAR_TARGETS_OF_MLL_AF9_FUSION | MSigDB lists | KUMAR_TARGETS_OF_MLL_AF9_FUSION | 384 | 73 | 15632 | 1249 |
Angpt1,Ifi207,Adar,Gpc1,Fcgr1,Sdc4,F10,Ifi214,Tpi1,Ifnb1,Irf4,Pla2g4a,Ctsc,Cited2,Spic,Psip1,Hivep2,Ifit1bl1,Ifit3b,Ifi204,Odc1,Pim2,Mmp9,Ell2,Dck,Mtdh,Hmgcs1,Ifi203,Pla2g7,Ifi211,Ptch1,Hdc,Mndal,Ifit3,Atm,Cd83,Gnb4,Arg2,Isg15,Spata13,Usp18,Upp1,Mcoln2,Pml,Slc30a4,Ccng2,Rsad2,C1ra,Rbpms,Ifi205,Ifi209,Abcc5,Ifit2,Ifi213,Cmpk2,Pkp4,Gng12,Vcam1,Gtpbp2,Il1rn,Ttc39b,Cdc42ep4,Slc31a1,Ptger4,Cd55,Hk2,Inhba,Ifi208,Map2k1,Irf7,Ccl5,Txn1,Ifit1bl2 |
| 2.114e-12 | -26.88 | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_DN | 185 | 46 | 15632 | 1249 |
Dcbld2,Plcl2,Il1rn,Thbs1,Plat,Ptgs2,Il12b,Gpr85,Serpinb9,Map3k8,Rnf19b,Ppp2r3a,Ext1,Myo1b,Lad1,Fzd5,Apaf1,Plagl2,Ch25h,Mcoln2,Errfi1,Nr3c1,Gpr84,Arhgef3,Dusp16,Tax1bp1,Rcsd1,Ebi3,Mmd,Met,Rhou,Nfkbib,Hdc,Rabgef1,Nfkb1,Klf7,Rras2,Fpr2,P2ry14,Nfkbiz,Dtnb,Edn1,Dusp2,Igsf6,Rab32,Sqstm1 |
| 2.125e-12 | -26.88 | KANG_GIST_WITH_PDGFRA_UP | MSigDB lists | KANG_GIST_WITH_PDGFRA_UP | 57 | 24 | 15632 | 1249 |
Lcp2,Irf8,Mndal,Ifit1bl2,Pde7b,Ifi203,Ifi211,Ifi208,Ifi204,Tgfbi,Cxcl10,Ppp2r1b,Kdr,Ifi209,Ifi205,Ifit1bl1,Ifi213,Cxcl14,Tnc,Pde1b,Usp18,Ifi214,Isg15,Ifi207 |
| 2.218e-12 | -26.83 | GO_POSITIVE_REGULATION_OF_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_PROLIFERATION | 751 | 116 | 15632 | 1249 |
Jun,Ccl12,Cx3cr1,H2-Q4,Flt1,Nod2,Myc,Il6,Peli1,Edn1,Ccr3,Phip,Egr1,Atf3,Htr2a,Plau,Sirt1,Htra1,Adrb2,Stat1,Ebi3,Tnfsf4,Nox1,Igf1r,Kdr,Hcls1,Clcf1,Cd40,Timp1,Acvrl1,Mdm2,Ccnd1,Kdm5b,Pnp2,Sphk1,Calcrl,Hif1a,Pml,Lif,Hlx,Marcksl1,H2-Q7,Hck,Notch1,Bmp2,Cd86,Nampt,Csf3,Pdgfb,Ptafr,Il12b,Cxcl10,Ptgs2,Dnaja2,Cd55,Ptger4,Vegfc,Bambi,Itgav,Syk,Plac8,Spn,Nr4a1,S1pr2,Pla2g4a,Irs2,Cx3cl1,Col18a1,Nck1,Cd80,Tspo,Il15,Cav1,Pid1,Ednrb,Rictor,Csf1,Lyn,Odc1,Ptk2,Egr3,Cdkn1a,Jak2,Bcl6,H2-Q6,Tnf,Stat5a,Hdac1,Mecp2,Tnc,Stat3,Cd74,Tnfaip3,Pdgfc,Etv5,Cd38,Pbx1,Ccdc88b,Osm,Pdgfrb,Cd274,Ccl5,Il12rb1,Bst1,Icosl,Nrp2,Il18,Nr4a3,Hmox1,Ripk2,Crkl,Il1b,Htr2b,Gcnt2,Kitl,Vcam1 |
| 2.268e-12 | -26.81 | regulation of lymphocyte differentiation | biological process | GO:0045619 | 184 | 42 | 20694 | 1406 |
Nfkbiz,Fas,Il15,Il4ra,Nfkbid,Ifnb1,Zc3h12a,Malt1,Ptpn2,Ctla2a,Fgl2,Il18,Bcl6,Pik3r6,Zeb1,Il1b,Cd83,Nlrp3,Lgals9,Il15ra,Axl,Cd74,Mmp14,Il6,H2-Aa,Syk,Ap3b1,Socs1,Ripk2,Hlx,Il2rg,Stat5a,Egr3,Tnfsf9,Irf1,Ikzf1,Slamf8,Tlr9,Il27,Prdm1,Rasgrp1,Tnfsf4 |
| 2.277e-12 | -26.81 | negative regulation of intracellular signal transduction | biological process | GO:1902532 | 504 | 79 | 20694 | 1406 |
Hsph1,Thbs1,Prnp,Bcl2a1a,Src,Dyrk2,Tank,Dusp5,Ptprj,Map2k1,Dusp2,Atm,Lif,Spred1,Dusp1,Hif1a,Lpar1,Mul1,Sesn3,Bcl2a1d,Dusp8,Ptgs2,Mdm2,Optn,Zc3h12a,Mmp9,Sirt1,Rgs14,Grina,Il1b,Dhx58,Rhoh,Nlrp3,Uaca,Itpr1,Stat1,Errfi1,Ikbkg,Tnfaip3,Lyn,Cav1,Tnip1,Myadm,Psmd10,Hdac1,Phlpp1,Met,Atf3,Casp8,Ezr,Plaur,Ddit4,Sh3bp4,Pde3b,Atp2b4,Dusp6,Rnf34,Bcl2a1b,Rffl,Sod2,Mapkbp1,Irak3,Bcl6,Pde4b,Dusp4,Aida,Ptpn2,Rcan1,Cd74,Spred3,Dnaja1,Igf1r,Dusp16,Spry2,Uchl1,Nfkbid,Cdkn2d,Rabgef1,Tnip3 |
| 2.305e-12 | -26.80 | regulation of cytokine biosynthetic process | biological process | GO:0042035 | 107 | 31 | 20694 | 1406 |
Rel,Cx3cr1,Il10,Nmi,Thbs1,Spn,Il27,Tlr9,Icosl,Myd88,Irf1,Stat3,Stat5a,Tnfrsf8,Tnf,Il1a,Il6,Syk,Ptafr,Mapkapk2,Il1b,Tlr1,Irf4,Zfp36,Nfkb1,Egr1,Tlr2,Tlr3,Tlr6,Jak2,Errfi1 |
| 2.370e-12 | -26.77 | GO_RESPONSE_TO_WOUNDING | MSigDB lists | GO_RESPONSE_TO_WOUNDING | 533 | 91 | 15632 | 1249 |
Adrb2,Mafg,Irf1,Prkar2b,Cflar,Actb,P2ry2,Gna15,Plscr1,Procr,Bcl9,Plau,Ifna1,Jun,Slc7a11,Ccl12,Flrt3,Pik3r5,Cx3cr1,Sdc2,Prkce,Il6,Pdpn,Lox,Pf4,Dcbld2,Plaur,Serpinb2,Pik3r6,Dgka,Adora2a,Maff,Ifna6,Pdgfb,Il1a,Hif1a,Irf2,Rhoc,Notch1,Cd40,P2ry12,Itpr1,Timp1,Axl,Ehd1,Src,Acvrl1,Casp3,Lyn,Map2k4,Itga9,C3,Itga5,Dgkh,Max,H3f3b,Notch2,Arf4,Jak2,Cav1,S100a8,Cx3cl1,Papss2,Sdc1,Stxbp1,Enpp4,Tspo,Cd34,F10,Sdc4,Syk,Ifnb1,Ifna5,Ap3b1,Ifrd1,Hmox1,Il1b,Plat,Pdgfrb,Lcp2,Gja1,Csrp1,Ccr1,Plek,Stxbp3,Ifna2,Pdgfc,Klf6,Mafk,Hdac1,Tnc |
| 2.432e-12 | -26.74 | GSE6674_UNSTIM_VS_CPG_STIM_BCELL_UP | MSigDB lists | GSE6674_UNSTIM_VS_CPG_STIM_BCELL_UP | 128 | 37 | 15632 | 1249 |
Csrp1,Ttc9c,Clic5,Serpine1,Adap2,Asah2,Cd86,Marco,St3gal5,Tyk2,Ptgir,Cd200,Xkr8,Max,Il12b,Tnfsf10,Klf6,Axl,Dse,Mtus1,Pde1b,Dbnl,Pla2g4a,Acvrl1,Hdac1,Stxbp1,Rhoh,Ch25h,Psmb10,Slco3a1,Sla,Gys1,Pim3,Myd88,Mvp,Hck,Crim1 |
| 2.504e-12 | -26.71 | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | 32 | 18 | 15632 | 1249 |
Ifi213,Gsdmd,Casp1,Ifnar1,Ifi205,Ifi209,Mndal,Ifi211,Ifi208,Nod2,Ifi203,Aim2,Ifi204,Nlrp3,Ifi214,Jak2,Nod1,Ifi207 |
| 2.588e-12 | -26.68 | ONKEN_UVEAL_MELANOMA_UP | MSigDB lists | ONKEN_UVEAL_MELANOMA_UP | 699 | 110 | 15632 | 1249 |
Slc7a8,Gch1,Ifi208,Wars,Hk2,Ptger4,Larp1,Cd55,Grina,Ak4,Nsmaf,Clic4,Tcea1,Ifi213,Hsph1,Casp1,Plekhf2,Psmb9,Ifi205,Tbc1d1,Cebpd,C1ra,Tapbp,Isg15,Abtb2,P4ha1,Zc3h7a,Htra1,Ifi203,Met,Stat1,Phf11d,Acsl1,Ier3,Actb,Tnfaip2,Asf1a,Kdr,Hcls1,Dock4,Tgs1,Rai14,Tra2a,Nqo1,Abr,Egr1,Lrp8,Ccnd2,Pfkfb3,Phf11c,Hsd17b12,Gdf15,Tor1aip1,Fzd5,Sap30,Ext1,Parp12,Atp10a,Rcan1,Pcdh7,Pilrb1,Sp110,Phf11b,P4ha2,Plod3,Ifi209,1110038F14Rik,Slc39a4,Hdac1,Cers6,Rnf139,Cd74,Fabp3,Traf5,Atm,Gem,Lap3,Mndal,Ifi211,Psme2,Syne2,Kctd12,Ptk2,Egr3,Mtdh,Trib1,Ifi204,Lyn,Rbms1,Cdkn1a,Abcc1,Nfil3,Gsdmd,Sod2,Ass1,Ptpn2,Ets2,Ctsc,Cnot4,Ddx60,Bcor,Col18a1,Cdk5r1,Ifi214,Pilrb2,Sgcb,Phf11a,Ifi207,Me1,Dusp14 |
| 2.597e-12 | -26.68 | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 186 | 46 | 15632 | 1249 |
Il15,Olr1,Tlr6,Nek6,Sgms2,Peli1,Parp14,Spry2,Cpd,Chst11,Slc7a11,Rnf114,Ifit1bl1,Tnfaip2,Gfi1,Igf1r,Tagap,Il13ra1,Ebi3,Acsl1,Ampd3,Alas1,Cd69,Tnfrsf1b,Sik3,Pbx1,Mcm10,Irf2,Pigv,Sertad3,Rsad2,Fgl2,Treml2,N4bp1,Tnf,Slc25a37,Bcl6,Mtus1,Sp110,Xkr8,Pim1,Stx11,Bst1,Nfkbid,Ifit1bl2,Plek |
| 2.597e-12 | -26.68 | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP | 186 | 46 | 15632 | 1249 |
Il1b,Serpinb2,Il2rg,Osgin2,Slc43a3,Pim1,Dusp5,Hk2,Cd274,Myo1b,Crim1,Sav1,Kmo,Il1a,Zfp513,H2-Q7,Rsad2,Cish,Tank,H2-Q6,Dync1h1,Tnf,Abcc1,Cdkn1a,Mob3c,Tnip1,Clcn7,Itga5,C3,Rhou,Ccrl2,Ampd3,Trim21,Ubr4,Zc3h12c,Sdc4,Rtp4,Mllt6,Tgs1,Gpr35,Gclm,Irf4,Dnaja1,Pik3r5,H2-Q4,Hivep2 |
| 2.726e-12 | -26.63 | HIN-200 | interpro domains | IPR040205 | 12 | 11 | 19984 | 1430 |
Ifi205,Ifi211,Ifi204,Ifi209,Ifi214,Ifi203,Ifi213,Ifi208,Ifi207,Mndal,Aim2 |
| 2.825e-12 | -26.59 | GSE3920_UNTREATED_VS_IFNA_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_UNTREATED_VS_IFNA_TREATED_ENDOTHELIAL_CELL_UP | 160 | 42 | 15632 | 1249 |
Itgav,Jun,Serp1,Csf3r,Tpst1,Dock4,Tgs1,Slc15a3,Pdpn,Fgl2,Plk3,Hlx,Ubash3b,Plau,Olfml3,Dusp6,Plek,Slc31a2,Il10,Samsn1,Cd86,Csf1,Nrp2,Fabp7,Tmem176a,Pde7b,Fndc3a,Hmox1,Tlr3,Lyn,Gpd2,Il18,Mafg,Phyh,Rgs1,Slc29a3,Cd300lf,Cflar,Htr2b,Glrx,Dusp16,Fmnl2 |
| 2.825e-12 | -26.59 | GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | MSigDB lists | GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | 200 | 48 | 15632 | 1249 |
Cd200,Rcn1,Rcsd1,Ier3,Ifit3b,Igf1r,Lrrc8c,Ifit3,Ogfr,Ube2e2,Ddx60,Ccl22,Slc30a1,Psip1,Dnaja1,Il4i1,Tlr3,Ptger4,Fndc3a,Adora2b,Mob3b,Ttc39b,Pcdh7,Slfn3,Gtpbp2,Ikbke,Rcl1,Ccnj,Igsf9,Slfn4,Btg2,Phlda1,Sh3bp4,Car13,Parp12,Vasp,Tyk2,Ier2,Tab2,Traf5,Pbx1,Cd14,Ube2f,Mvp,Tank,1110038F14Rik,Cp,Batf2 |
| 2.872e-12 | -26.58 | regulation of cytokine production involved in immune response | biological process | GO:0002718 | 83 | 27 | 20694 | 1406 |
Tlr3,Tlr2,Hmox1,Hk1,Nr4a3,Ddx58,Ifnb1,Nod2,Tnfrsf14,Il18,Malt1,Fzd5,Tnfrsf1b,Irak3,Bcl6,Nlrp3,Il1b,Cd74,Traf2,Il6,Tnf,Rsad2,Angpt1,Tlr9,Tnfsf4,Arid5a,Il10 |
| 2.882e-12 | -26.57 | MODULE_223 | MSigDB lists | MODULE_223 | 141 | 39 | 15632 | 1249 |
Il1a,Cdk5r1,Sell,H2-Q7,Mxd1,Lif,Mthfr,Prdx1,Cd83,Il15,Tspan3,Timp1,H2-Q6,Csf3r,Bcl6,Klf6,H2-Q4,P4ha2,Edn1,Myc,Il6,Tgfbi,Il18,Il2rg,Cxcl10,Hp,Il15ra,Il1b,Cd86,Osm,H2-Eb1,Nampt,Csf3,Cd69,Isg20,Csf1,Pdgfb,Zeb1,Tlr1 |
| 3.000e-12 | -26.53 | GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP | 180 | 45 | 15632 | 1249 |
Mthfd2,Il13ra1,Stat1,Jak2,Lmo4,Gbp7,Pdk3,Psmb8,Tor3a,Plscr1,Isg20,Plagl1,Pgm1,Samhd1,Pnpt1,Cd34,Ptpn2,Znfx1,Sod2,Irgm2,Grina,Cmpk2,Cxcl1,Map2k1,Klf2,Nampt,Snx10,Caml,Ext1,Isg15,Ifih1,Usp18,Pml,Psme1,Myo10,Mvp,Rab3ip,Cd14,Myd88,Ifit2,Cebpd,Rsad2,Ly75,Ccdc86,Mdn1 |
| 3.040e-12 | -26.52 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN | 135 | 38 | 15632 | 1249 |
Pim3,Etv3,Traf1,Isg15,Irs2,Mxd1,Csrnp1,Mafk,Errfi1,Ifnb1,B3gnt5,Rab11fip1,Peli1,Homer1,Gadd45b,Nr4a1,Ifit2,Tnf,Ifit1bl1,Irak2,Ptgs2,Irf1,Cxcl10,Ifit3b,Nr4a3,Ptger4,Kdm6b,Sirt1,Nfkbid,Rnf19a,Zc3h12c,Ifit3,Gem,Irf7,Osm,Nampt,Pde4b,Ifit1bl2 |
| 3.147e-12 | -26.48 | GOZGIT_ESR1_TARGETS_DN | MSigDB lists | GOZGIT_ESR1_TARGETS_DN | 648 | 104 | 15632 | 1249 |
Procr,Rasgrp1,Jag1,Ltbp2,Psmb8,Pdk3,Dach1,Birc3,Lcn2,Ifit3,Kdr,Sh3bgrl2,Tmem219,Igf1r,Stat1,Edn1,Samd9l,Flrt3,Ifit1bl1,Jun,Rbms2,Rnd3,Egr1,Nfkbiz,Ppm1l,Tmtc2,Prnp,Oas2,Sesn3,Ifit1bl2,Slc7a2,Myo1b,Plk2,Ppm1k,Bambi,Thbs1,Tnfsf10,Zhx2,Vegfc,H2-Ab1,Herc6,Ak4,Tgfbi,Dusp8,Dennd1b,Rhoq,Fut8,Timp1,Gbp2,Hhex,Sell,Spata13,Pstpip2,Isg20,Egln3,Xaf1,Hk1,Sema3c,Znrf1,Pmepa1,Frmd6,Abcc1,Egr3,Ifit3b,Mmp25,Lrch1,Nat2,Cnot4,Ahr,Atp11b,Klf7,Nek6,Col18a1,Evl,Papss2,Arl4a,Degs2,Ccl5,Gdf15,Irf7,Kitl,Pcdh7,Sp110,Pcgf5,St3gal1,Arid5b,Batf2,Cp,Itgb8,Sat1,Cers6,Rbpms,Slc16a3,Plekha5,Ifit2,Tcf4,Bcl6,Batf,Tnfaip3,Mvp,Parp10,Arg2,Slc39a13,Usp18 |
| 3.186e-12 | -26.47 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | biological process | GO:0002824 | 135 | 35 | 20694 | 1406 |
Cd274,Nectin2,Nlrp3,Il12b,Il1b,C3,Il18,Fzd5,Malt1,H2-T24,Clcf1,H2-Q4,Tap2,H2-Q7,Il12rb1,H2-T22,Nod2,Nfkbid,H2-T10,Nfkbiz,Cd40,Tnfsf4,Arid5a,H2-Q6,Pvr,Irf1,H2-Ab1,H2-M2,Fcgr1,Tnf,Rsad2,Ripk2,Hlx,Traf2,Il6 |
| 3.287e-12 | -26.44 | cellular response to lipid | biological process | GO:0071396 | 546 | 83 | 20694 | 1406 |
Gbp2,Pf4,Nfkbia,Ccl2,Myd88,Cx3cr1,Il10,Ccl12,Gch1,Arid5a,Nr4a1,Ddit4,Glrx,Tnfsf4,Ptger4,Cxcl1,Tnf,Daxx,Pde4b,Malt1,Fcgr4,Zfp36,Cd14,Cd180,Il1rn,Il12b,Nr1h3,Mtdh,Dnaja1,Stap1,Serpine1,Ifnb1,Nod2,Cxcl2,Ccl5,Tnip3,Nfkbil1,Nr3c1,Src,Plscr1,Cmpk2,Casp1,Pdk3,Ldlr,Cd86,Atm,Il6,Cd80,Klrk1,Cxcl9,Cxcl10,Ptafr,Ripk2,Lpar1,Irgm2,Nos2,Irak2,Tnfrsf1b,Zc3h12a,Il18,Pid1,Gramd1a,Gfi1,Irf8,Axl,Il1b,Nlrp3,Cd274,Nfkbib,Jak2,Stat1,Acod1,Ptch1,Tnfaip3,Lyn,Inhba,Cxcl3,Nfkb1,Ahr,Pim1,Cxcl11,Prkce,Nr4a3 |
| 3.327e-12 | -26.43 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | 194 | 47 | 15632 | 1249 |
Odc1,Ell2,Lrrc8c,Ccl4,Adam19,Casp4,Tnfrsf1b,Il18rap,Plscr1,Nfkbib,Pttg1,Gpc1,Fos,H2-Q4,Gadd45b,Bcl2a1b,Cox17,Fcgr2b,Phyh,Pim1,Rnf19b,Glrx,Bcl2a1a,Cldnd1,Kitl,Tnfsf10,Hopx,Fosb,Snx10,Txn1,Ccl5,St3gal6,Slco3a1,Fgr,Gbp3,Itga4,H2-Q7,Tnfaip3,Mdfic,H2-Q6,Klf6,N4bp1,Cst7,Casp1,Fgl2,Errfi1,Bcl2a1d |
| 3.409e-12 | -26.40 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_DN | 148 | 40 | 15632 | 1249 |
Ifit1bl1,Fam43a,Ifit2,Sp140,Ifi44,Stap1,Dhx58,Samd9l,Atf3,Lif,Palld,Usp18,Ifih1,Isg15,Intu,Slamf7,Ifit1bl2,Pde4b,Fzd5,Ifit3,Osm,Isg20,Plscr1,Sh3bp4,Oas1a,Xaf1,Rhou,Cxcl2,Oas2,Tdrd7,Herc6,Oasl1,Oas1g,Osgin2,Cxcl10,Ifit3b,Ccl4,Tnfsf10,Lacc1,Epsti1 |
| 3.439e-12 | -26.40 | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_DN | MSigDB lists | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_DN | 174 | 44 | 15632 | 1249 |
Ap3b1,Dusp4,Mid1,Parp14,Msr1,Jun,Gadd45b,Sbds,Rtp4,Srxn1,Slpi,St3gal5,Casp4,Adap2,Ikbkg,Hsd17b7,Frmd6,Jak2,Ccl4,Tnip1,Mtmr14,Errfi1,Mdm2,Arid5a,Csf3r,Ehd1,Relb,Pbx1,Arg2,Ch25h,Maff,Gpr132,Phlda1,Slfn4,Rcl1,Vcam1,Slfn3,Ralgds,Clec5a,Slc43a3,Osgin2,Serpinb9,Map3k8,Rnf19b |
| 3.468e-12 | -26.39 | JOHNSTONE_PARVB_TARGETS_3_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_3_UP | 388 | 73 | 15632 | 1249 |
Nfkbia,Nlrc5,Agrn,Sqstm1,Cited2,Optn,Cpd,Col18a1,Prnp,Slc30a1,Nr1h3,Plau,Rras2,Cdc42ep2,Atp2b4,Ppfibp1,Samhd1,Atm,Eno2,Mov10,Sik3,Csf1,Htra1,Flnb,Jag1,Ifi35,C3,Uaca,Rcn1,Trib1,Acsl1,Notch2,Actb,Tnfaip2,Tax1bp1,Ldlr,Tnip1,Rnaset2b,Slc25a37,Dync1h1,Klf6,Ehd1,Psmb9,Timp1,Fut8,Errfi1,Arhgap26,Ccnd1,Cebpd,Prdx5,Tapbp,Lif,Icam1,F11r,Lipg,Mvp,Mdfic,Rnaset2a,Daam1,Ddit4,Phlda1,Parp12,St3gal1,Cd55,Dusp5,Hmox1,Tgfbi,Cdc42ep4,Acsl5,Osbpl3,Thbs1,Tnfsf10,Irak2 |
| 3.523e-12 | -26.37 | positive regulation of cytokine biosynthetic process | biological process | GO:0042108 | 72 | 25 | 20694 | 1406 |
Egr1,Tlr2,Tlr3,Tlr6,Jak2,Mapkapk2,Il1b,Tlr1,Irf4,Stat5a,Tnf,Tnfrsf8,Il1a,Il6,Syk,Ptafr,Rel,Thbs1,Spn,Il27,Tlr9,Icosl,Irf1,Stat3,Myd88 |
| 3.655e-12 | -26.33 | KEGG_LEISHMANIA_INFECTION | MSigDB lists | KEGG_LEISHMANIA_INFECTION | 63 | 25 | 15632 | 1249 |
Il1b,Myd88,Jak2,Fcgr1,Il1a,Tab2,Ptgs2,Il12b,Tlr2,H2-Ab1,Marcksl1,Itga4,C3,Stat1,Nfkbib,H2-Aa,Il10,Fos,Jun,Nos2,Nfkbia,H2-Eb1,Fcgr4,Tnf,Nfkb1 |
| 3.655e-12 | -26.33 | GO_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | MSigDB lists | GO_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 63 | 25 | 15632 | 1249 |
Tnf,Traf2,Birc2,Tank,Nfkbil1,Tab2,Nkiras1,Cd14,Ripk3,Relb,Birc3,Nfkb1,Ikbkg,Rnf31,Tnfsf14,Rel,Tifa,Tlr9,Tlr3,Ripk2,Azi2,Tlr2,Ikbke,Irak2,Nfkb2 |
| 3.690e-12 | -26.33 | GSE3982_DC_VS_NKCELL_UP | MSigDB lists | GSE3982_DC_VS_NKCELL_UP | 181 | 45 | 15632 | 1249 |
Tuba4a,Slc31a2,Ppp2r3a,Nr4a3,Adora2b,Ak4,Slc31a1,Il1rn,P4ha2,Cers6,Treml2,Nfkbie,Socs1,Kmo,Tab2,Magohb,Hlx,Pdgfc,Cd83,Tor3a,Hivep3,Alas1,Ampd3,Csf1,Rab20,Asb13,Il13ra1,Mmp9,Ptk2,Dram1,Cdkn1a,Esd,Tnip1,Fscn1,Dhrs9,Cenpe,Scarf1,Nqo1,Igsf6,Fcgr2b,Ggct,Arl4a,Ccl22,Stxbp1,Atf3 |
| 3.693e-12 | -26.32 | positive regulation of tumor necrosis factor production | biological process | GO:0032760 | 96 | 29 | 20694 | 1406 |
Thbs1,Hdac1,Tlr9,Pf4,Spn,Myd88,Ccl2,Ptprj,Rasgrp1,Arid5a,Ccl4,Ptafr,Ripk2,Tnfrsf8,Ccl3,Fzd5,Il18,Cd14,Lgals9,Mapkapk2,Il12b,Tlr1,Tlr3,Ifih1,Jak2,Nod2,Nod1,Ddx58,Tlr2 |
| 3.700e-12 | -26.32 | phosphorus metabolic process | biological process | GO:0006793 | 1745 | 193 | 20694 | 1406 |
Ikbke,Ak4,Pdgfb,Lif,Ptafr,Flt1,Oas1a,Map2k1,Pdk3,Ampd3,Smpdl3b,Src,Stat3,Hck,Itpkc,Rictor,Il12rb1,Trib1,Pgk1,Cycs,Ripk3,Tyk2,Sphk1,Jak2,Akt3,Hk3,Stat5a,Map3k8,Ppm1k,Eif2ak2,Socs1,Mecp2,Inpp1,Socs3,Scyl2,St3gal1,Tlr9,Cept1,Pgs1,Ccng2,Il15,Dusp14,Dgkh,Rhoq,Ppa1,Dusp16,Ptk2,Ppp4r2,Prkx,Kmo,Prag1,Pde5a,Myc,Ptpn2,Pdgfrb,Ciita,Saa3,Dusp8,Pgap2,Dusp1,Acvr1b,Ccnd2,Bmp2,Samhd1,Grk3,Plk2,Dck,Plek,Ppp2r5a,Ppm1l,Prkce,Cdk5r1,Ccnd1,Tlr3,Hk2,Itgav,Mapkapk2,Mppe1,Trib3,Sla,Ppp2r3a,Pim3,Il1b,Acp2,Extl2,Mlkl,Acp5,Inpp5b,Mdfic,Ubash3b,Gfpt1,Phlpp2,Sik3,Kdr,Dusp6,Plaat3,Nampt,Pikfyve,Eno2,Pla2g4a,Nck1,Met,Myd88,Acvrl1,Fut8,Hmgcs1,Mark2,Dusp4,Ppp1r15a,Stk40,Ripk2,Mul1,Pfkfb3,Gpd2,Nek6,Cmpk2,Ccne1,Dgka,Idi1,Tlk2,Ptprj,Map4k4,Dyrk2,Plpp1,Tlr2,Pim1,Mocs1,Irak2,Il18,Ptger4,Plpp3,Cnp,Map2k4,Acvr1,Ppp1r15b,Phlpp1,Gk,Pigv,Pla2g7,Papss2,Sgms2,Socs7,Cish,Sgk3,Morc3,Mtmr14,Ccr3,Irak3,Zfp36,Ksr1,Oasl2,Mmd,Mgat1,Minpp1,Upp1,Atm,Acsl1,Tpi1,Dusp2,Ppp2r2a,Pik3cd,Plscr1,Dusp5,Osm,Lyn,Htr2b,Axl,Acsl5,Fam20c,Plcl2,Tnf,Mapkbp1,Plk3,Syk,Stat4,Agpat4,Pml,Acpp,Pim2,Ccnj,Eya4,Ccl12,Etnk1,Hk1,Ccl5,Pfkl,Igf1r,Map3k6,Vrk2,Fgr,Dusp28,Lpcat2,Nt5c3 |
| 3.794e-12 | -26.30 | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | MSigDB lists | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | 748 | 115 | 15632 | 1249 |
Ltbp2,Lnpep,Met,Ier3,Ell2,Denr,Ppa1,Tmod3,Clcf1,Tiparp,Bcl2l11,Ccl12,Edn1,Myc,Prnp,Il4ra,Abr,Atf3,Chmp4b,Prdx1,Plau,Lad1,Fubp1,Slc7a8,Txn1,Junb,Btg2,Slc7a5,Tgfbi,Pim1,Mob3b,Cd55,Smox,Zc3h12a,Gng12,Tcea1,Osbpl3,Thbs1,Serpinb2,Dse,Eno1,Parp8,Apobec3,Dennd1b,Pnp2,Malt1,Pml,Mthfr,Myo10,Rhoc,Smg7,Cav1,Plod2,Cep350,Ikbkg,Nfkb1,Trim56,Stx6,Syne2,Slc9a1,Lpar1,Ptk2,Mmp9,Nfil3,Frmd6,Pmepa1,Dnajb2,Cdkn1a,Notch2,Tax1bp1,Chd9,Adam19,Casz1,Ets2,Klf3,Itgav,Syk,Rin2,Ifrd1,Pcx,Arl4a,Spred1,Klf7,Ahr,Olr1,Dusp14,Extl2,Gpc1,Slc48a1,Atp6v1d,Serpine1,Dusp6,Brd2,Ext1,Fcho2,Il18,St7,Ptges,Arhgef3,Tcf4,Klf6,Txnrd1,Phldb1,Mafk,B3gnt5,Sat1,Micall2,Tnc,Upp1,Slc39a13,F11r,Prrg4,Csrnp1,Tsku,Sav1 |
| 3.895e-12 | -26.27 | GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 188 | 46 | 15632 | 1249 |
Klf3,Ifit1bl1,Itgav,Rapgef5,Sbds,Ppp2r5a,Cd200r4,Rin2,Nck1,Il4ra,Slamf7,Il10,Gna15,St3gal5,Ampd3,Mmd,Leng9,Pou2f2,Endod1,Irf1,Chd9,Igf1r,Rnaset2b,Ap3m2,Ttc39c,Itgb8,Rnf139,Icam1,Sell,Crlf3,1600014C10Rik,Sla,Crim1,Hvcn1,Ifit1bl2,Myadm,Hopx,Rnaset2a,Rnf19b,Nr4a3,Tapbpl,Ttc39b,Il18,Sec24a,Inpp1,Glrx |
| 3.911e-12 | -26.27 | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_DN | MSigDB lists | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_DN | 168 | 43 | 15632 | 1249 |
Prkce,Fcgr2b,Chst11,Sbds,Phf11a,Il15,Phf11c,Atp2b4,Pttg1,Cysltr2,Il18rap,Smpdl3b,Stat4,Jdp2,Gem,Itgal,Ccl4,Rgs1,Nfil3,Gpd2,Phf11d,Carhsp1,Pnp2,Mlkl,Arhgap26,Cst7,Insl6,Phf11b,Ttc39c,Swap70,Cd38,Prdm1,Sap30,Myadm,Snx10,Slc4a7,Samsn1,Hopx,Prkx,Ptprj,Serpinb9,Map3k8,Ttc39b |
| 4.032e-12 | -26.24 | GO_LEUKOCYTE_MIGRATION | MSigDB lists | GO_LEUKOCYTE_MIGRATION | 237 | 53 | 15632 | 1249 |
Ccl22,Cx3cl1,Cd34,Slc16a1,Angpt1,Olr1,Cx3cr1,Spn,Flt1,Sbds,Itgav,Ccl12,Slc7a11,Syk,Edn1,Ccl2,Il6,Itga5,Mmp9,Itga9,Lyn,Pik3cd,Ccl4,Trem1,S100a8,Ednrb,Cav1,Il10,Itgal,Procr,Itga4,Cd74,F11r,Icam1,Sell,Ccl3,Hck,Src,Tnf,Slc16a3,Csf3r,Sele,Cxcl10,Vcam1,Pf4,Il1b,Slc7a8,Pde4b,Ccr1,Ccl5,Pdgfb,Slc7a5,Cxcl2 |
| 4.073e-12 | -26.23 | BMI1_DN_MEL18_DN.V1_UP | MSigDB lists | BMI1_DN_MEL18_DN.V1_UP | 130 | 37 | 15632 | 1249 |
Ehd1,Slc7a11,Tagln,Edn1,Itgb8,Ogfrl1,Chst11,Ccnd1,Itga4,Atf3,Lif,Il1a,Arl4a,Tnfrsf8,Cdc42ep2,Klf7,Psat1,Birc3,Csf1,Nrp2,Piezo1,Slc7a5,Inhba,Jag1,Bst1,Itga5,Zc3h12a,Trib3,Tnip3,Pim1,Adrb2,Plat,Adam19,Vegfc,Plaur,Pmepa1,Tfec |
| 4.134e-12 | -26.21 | VERHAAK_AML_WITH_NPM1_MUTATED_DN | MSigDB lists | VERHAAK_AML_WITH_NPM1_MUTATED_DN | 230 | 52 | 15632 | 1249 |
H2-Aa,Ifi208,Sh3bp4,Pde4b,Gja1,Hopx,Zhx2,Ptger4,Clec5a,Ak4,Tgfbi,Ifi44,Rbpms,Ifi213,Cst7,Gypc,Dse,Gpsm2,Ifi205,Csf3r,Ifi209,Traf5,Cd38,Mdfic,Ifi211,Isg20,Flnb,Ifi203,Cd69,Dach1,Cav1,Lcn2,Lmo4,Mndal,Rgs1,Endod1,Cd200,Mmp9,Ptgir,Ifi204,Abcb1a,Stap1,Optn,Ezr,Ass1,Cd34,Ciita,Pde3b,Ifi207,Evl,Ccnd2,Ifi214 |
| 4.174e-12 | -26.20 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | 124 | 36 | 15632 | 1249 |
Vcam1,Adam19,Thbs1,Lpar1,Ifi204,Lox,C3,Ifi203,Tmem176a,Csf1,Ifi211,Noc4l,Phlda1,Plscr1,Ifi208,Mndal,Casp4,Pdk3,Eno2,Ltbp2,Ifi207,Slc16a1,Ifi214,Tmem176b,Evl,Vcan,Errfi1,Cebpd,Tnc,Pdpn,Il6,Ifi205,Tpst1,Ifi209,Ifi213,Ccl12 |
| 4.247e-12 | -26.18 | GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 175 | 44 | 15632 | 1249 |
Pilra,Atp2b4,Olr1,Mapkapk2,Il4ra,I830077J02Rik,Rhof,Dr1,Kpna3,Max,Oasl1,Srxn1,Isg20,Stx6,Jdp2,Nfkb1,P2ry2,Hck,F11r,Tab2,Sertad3,Rab21,Nfkbie,Stk40,Dusp1,Ifnar1,Dse,Zmynd15,Plcl2,Inpp1,Ptges,Sp110,Xkr8,Zc3h12a,Dnaja2,Chic2,Serpinb9,Pdlim7,Nfkbid,Snx10,Tor1aip1,Higd1a,Sipa1l1,Med21 |
| 4.283e-12 | -26.18 | GO_MOVEMENT_OF_CELL_OR_SUBCELLULAR_COMPONENT | MSigDB lists | GO_MOVEMENT_OF_CELL_OR_SUBCELLULAR_COMPONENT | 1162 | 159 | 15632 | 1249 |
Rapgef2,Vasp,Cxcl2,Spint2,Ddit4,Nrp2,Ext1,Flrt2,Pdgfrb,Map2k1,Ccr1,Pde4b,Ccl5,Gja1,Il1b,Htr2b,Vcam1,Cxcl1,Plat,Kitl,Nr4a3,Arid5b,Sele,Stat3,Rab21,Csf3r,Tnf,Slc16a3,Ccl3,F11r,Cd74,Asap3,Syne2,Pstpip2,Slc9a1,Sema3c,Cav1,S100a8,Ednrb,Lhx2,Wdr43,Frmd6,Fscn1,Arf4,Jak2,Ccl4,Itga9,Lpar1,Ddx4,Lyn,Ptk2,Egr3,Sema4c,Itga5,Mmp9,Vcan,Ap3b1,Ift57,Phactr4,Parp9,Mmp14,Dnaja1,Nr4a1,Spn,Syk,Itgav,Klf7,Olr1,Cd34,Sdc4,Kif9,Tspo,Slc16a1,Gpc1,Sdc1,Fpr2,Cdk5r1,Cx3cl1,Evl,Nck1,Palld,Tyk2,Hap1,Pdgfb,Inpp5b,Slc7a5,Scn1b,Myo1b,Igsf8,Txn1,Slc7a8,Plaur,Vegfc,Pf4,Thbs1,Bambi,Prkx,Ptgs2,Il12b,Kif3c,Cxcl10,Fpr1,Uchl1,Acvr1,Acvrl1,Fut8,Egr2,P2ry12,Axl,Src,Dync1h1,Insl6,Notch1,Hck,Rhoc,Icam1,Hif1a,Spata13,Sell,Fgr,Itga4,Ier2,Apba1,Pml,Rasgrp1,Procr,Itgal,Il10,Trem1,Socs7,Ap3m2,Actb,Kdr,Sema4a,Pik3cd,Nox1,Kif5c,Stat1,Sdc2,Cxcl14,Edn1,Kcnj2,Ccl2,Il6,Pdpn,Dock4,Flt1,Cx3cr1,Ezr,Cenpe,Flrt3,Ccl12,Slc7a11,Sbds,Mark2,Atp2b4,Angpt1,Plau,Ccl22 |
| 4.420e-12 | -26.14 | myeloid leukocyte migration | biological process | GO:0097529 | 116 | 32 | 20694 | 1406 |
Ccl12,Cx3cr1,S100a8,Gpr35,Trem1,Ccl2,Pf4,Cx3cl1,Ccl3,Ccl7,Cxcl1,Ccl4,Cxcl10,Flt1,Mcoln2,Cxcl9,Syk,Pdgfb,Il1rn,Ccl9,Il1b,Ccr3,Ednrb,Itga9,Ccl8,Pde4b,Ccl22,Cxcl11,Ccl5,Cxcl2,Cxcl3,Csf3r |
| 4.531e-12 | -26.12 | GSE17721_POLYIC_VS_CPG_16H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_16H_BMDC_UP | 182 | 45 | 15632 | 1249 |
Phip,Aldh1b1,Ciita,Rbm43,Adar,Aff1,Plac8,Sbds,Zyx,Katna1,Slc44a1,Stat1,Asb13,Cdkn1a,Nfil3,Wdr43,Atm,Akt3,Psme2,Tdrd7,Irf2,Fabp3,1600014C10Rik,Cd164,Tnfaip3,Rhoc,Lrp4,Apobec3,Homer1,Gpsm2,1110038F14Rik,Casp3,Phgdh,Ccdc86,Top3a,Ythdf1,Atp10a,Grina,Slamf8,Brwd3,Brd2,Nrp2,Ube2l6,Tbc1d13,Parp12 |
| 4.531e-12 | -26.12 | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_UP | MSigDB lists | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_UP | 182 | 45 | 15632 | 1249 |
Il4i1,Slc44a1,Gadd45g,Gadd45b,Spsb1,Agrn,Spic,Pfkfb3,Gclc,Cd80,Nek6,Prnp,Zfp36,Eno2,Birc3,Dr1,Tnfaip2,Tnip1,Cdkn1a,Abcc1,Wdr43,Kpna3,Ppa1,Gpd2,Pdzd11,Stat3,Glipr2,Mafk,Tnf,Cd40,Cd83,Myo10,Tnfaip3,Relb,Traf1,Sphk1,Plk2,Il1rn,Rnf19b,Ptger4,Dnaja2,Psmb6,Ldha,Cxcl10,St7 |
| 4.580e-12 | -26.11 | KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY | MSigDB lists | KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY | 54 | 23 | 15632 | 1249 |
Il1b,Ccl4,Ikbke,Cxcl10,Il18,Nfkbib,Ifna6,Irf7,Nfkb1,Ccl5,Ikbkg,Ripk3,Ifna2,Ifna1,Zbp1,Adar,Ddx58,Aim2,Ifnb1,Ifna5,Il6,Nfkbia,Casp1 |
| 4.580e-12 | -26.11 | HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP | MSigDB lists | HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP | 54 | 23 | 15632 | 1249 |
Ripk2,Trib1,Ptgs2,Rab20,Ier3,Cxcl1,Ccl4,Plaur,Cdkn1a,Il1b,Glrx,Ppp1r15a,Btg2,Cxcl2,Atf3,Egr1,Nlrp3,Pfkfb3,Klf6,Sod2,Ets2,Egr2,Cebpd |
| 4.758e-12 | -26.07 | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_DN | MSigDB lists | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_DN | 189 | 46 | 15632 | 1249 |
Fgl2,Dusp1,Cd38,Gbp2,Zfp281,Arg2,Dtx3l,Prdm1,Mcoln2,Car13,Cxcl2,Nrp2,Rilpl1,Snx10,Il1b,Il1rn,Pim1,Grina,Fcho2,Ptgs2,Clec4d,Ptger4,St3gal1,Slc31a1,Chst11,Taf4b,Fcgr2b,Tiparp,Jun,Plac8,Ahr,Pfkfb3,Prdx1,Cd80,Clec4e,Nlrp3,Pgs1,Tmem176b,Pstpip2,Csf1,Hdc,Gem,Agpat4,Nfil3,Tnfaip2,Ppa1 |
| 4.849e-12 | -26.05 | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 169 | 43 | 15632 | 1249 |
Tuba4a,Lap3,Plekhg1,Itgal,Tap2,Ubr4,Nmi,Alas1,H2-Aa,St3gal5,Maff,Il12rb1,Pcgf5,Cd200,Oasl1,Dnajb4,Gbp2b,Jak2,Ddhd1,Tagln,Dhrs9,Parp8,H2-Q4,H2-Q6,Arhgef3,Dennd1b,Sat1,Edn1,Ctsc,Scarf1,Parp9,Nfkbie,Prrg4,H2-Q7,Malt1,Gbp3,Sertad3,Dtx3l,Ifih1,Kat2b,Clec4e,Extl2,Rgs3 |
| 4.868e-12 | -26.05 | cell periphery | cellular component | GO:0071944 | 5287 | 470 | 20747 | 1409 |
Pstpip2,Adrb2,Cd80,Sipa1l1,Hcar2,Gem,Vasp,Htra1,Igsf9,Tpm4,Lrp8,Syk,Cd200r4,Flt1,Klra2,Abcc1,Slc16a1,Katna1,Itga4,Lyn,Adgrg6,Daxx,Spred1,Ptch1,Ptgir,Mmp14,Lnpep,Znrf3,Mcoln2,Cemip2,Rasgrp1,Crlf3,Flrt2,Cdc42ep4,Gpc1,Hmox1,Rapgef2,Apba1,Lrp4,Hk2,Gpr132,Gpr18,Plekha2,Kdr,Clcn5,Gpr35,Ptafr,Calhm6,Nrp2,Dbnl,Carmil1,Zhx2,P2ry12,Hvcn1,S1pr2,Treml2,Vcam1,Micall2,Fzd5,Minpp1,Sell,Tapbp,Kcnj2,Birc2,Arl4a,Csf1,Antxr1,Il4ra,Xcr1,Ehd1,Sdc1,Cp,Slamf7,Rhoc,Cd74,Cd300e,H2-Q4,Slc30a1,Oas3,Ddx58,Gja1,Itga5,Cgas,Sgms2,Spire1,Slc31a1,Irak2,Tlr1,H2-Aa,Cflar,Ly6c2,Enpp4,Cdc42ep2,Rab9,Actb,Casp8,S100a8,Tnfsf10,Ksr1,Reps1,Rab10,Sema3c,Plpp3,Adora2a,Tlr9,Cd274,Itgal,Adap2,Mcmbp,Prnp,Vezt,Lcp2,Milr1,Ezr,Tmc3,Scimp,Cav1,Mfap3l,Acvr1b,H2-T10,Nfkbia,Dock4,Rab21,Gpr85,Slc44a1,Cx3cl1,Irgm1,Nod2,Kitl,Hk1,Rras2,Rims3,Msr1,Tarm1,Ms4a4b,Pvr,Stat3,Lpar1,Gypc,Plaur,Stau1,Gnb4,P2ry13,Itgav,Tulp3,Cd302,Hsd17b7,Errfi1,Slc39a14,Pilrb1,Fcgr2b,Marco,Asah2,Il13ra1,Gpsm2,Traf2,Rap2c,Irak3,Siglece,Slc28a2,Slc12a9,Clmp,Adgrl2,Dcbld2,Pcdh7,Homer1,Sema4c,Kremen1,Tmeff1,Stoml1,Rnd3,Il12rb1,Crkl,Cd38,Rnf34,Itgb8,Dst,Rgs3,Ppfia3,Il18,Gramd1a,Cacnb3,Sgcb,Csf3r,Stxbp3,Il18rap,Gpr68,Itpr1,Pdpn,Mosmo,Bmp2,Thbs1,Nlgn2,Myd88,Piezo1,Il15ra,Sema4a,Cdk5r1,Spry2,Slc2a6,Mpp7,Slc7a5,Cnp,Chmp4b,Rhbdf2,Gng11,Rhou,Selenow,Ptpn2,Casp3,Tnfsf14,Syne2,Clec4d,H2-T22,Clic4,Rtn2,Kcna3,Flrt3,Cx3cr1,Clec5a,Tspan3,Nod1,Nectin4,Spn,Dync1h1,Rgs1,Jmjd6,Myo1b,Cd14,Cldnd1,Slc16a3,Cmklr1,Prkar2b,P2ry14,Gng12,Xrn1,Angpt1,Pde4b,Arf4,Tlr3,Nectin2,Src,Gsr,Mmp25,Mark2,Mtus1,Myadm,Atp2b4,Abr,Eno1,Gng4,Chic2,Tmem123,Slc29a3,Bcorl1,Slco3a1,Samsn1,Tnfrsf14,Acpp,Cd180,Lipe,H60b,Traf5,Atp10a,Rilpl1,Ly75,Mdm2,Cxcl9,Triobp,Il2rg,Tnf,Xkr8,Abcb1a,Acsl1,Ccrl2,Pim1,Bst1,Frmd6,Stat2,Phlpp1,Cd164,Hck,Lrrc8c,Rgs14,Psd4,Rhoq,Cd55,Arid4a,Dgka,Jag1,Rhof,Fscn1,Olr1,Tlr2,Cacna1d,Cd83,Rac3,Marcks,Icosl,Clec2d,Atp11a,Sphk1,Gbp2b,Itga9,Cysltr2,Adam19,Fgr,Mtdh,Atp11b,Cxcl10,Ptk2,Slc7a2,Htr2b,Notch2,Ptger4,Ptgs2,Slc9a1,Nos2,Trip10,Dcun1d3,Ets2,Ednrb,Rffl,Slc2a1,Fchsd2,Cd34,Psd,Tmem67,Cd200,Clic5,Calcrl,Pdzd11,H2-Q7,Htr2a,Abcc4,Gca,Rpgrip1l,Notch1,Slc7a11,Pik3r6,Plscr1,Tlr6,Tnfsf9,Uchl1,Prokr1,Cd86,Cpeb4,H2-T24,Stxbp1,Slc7a8,Slc39a4,H2-Q6,Akt3,Palld,Slc31a2,Hspa1a,Pkp4,Hcls1,Gpr84,Cd300lf,Slc30a4,Cd69,Tnfaip2,Rnf114,Slc48a1,Pik3cd,P2ry2,Fpr1,Fzd1,H2-M2,Tnfsf15,Icam1,Agrn,Cd82,Acvr1,Gm5150,Spred3,Axl,Map2k1,Myo10,Ccr1,Pdgfb,Klrk1,Igsf8,Bambi,Rab19,Adgre4,Socs7,Plek,Phldb1,Gna15,Tapbpl,Pdgfrb,Fnbp1l,Pik3r5,Spata13,Cd40,Ifitm1,Cenpj,Samhd1,Fcgr4,Arrdc4,Nampt,Dnajb4,Il6,Stra6l,Treml4,Scn1b,Flnb,Ebi3,Cish,Lratd2,Rhoh,F11r,Acvrl1,Fabp7,Ly6a,Phlpp2,Osbpl3,Rap1gap2,Slc4a7,Fas,Met,Gsdmd,Fcgr1,Plpp1,Rnf31,Ccr3,Sele,Stx11,Swap70,Pdgfc,Agtrap,Rab20,Ripk3,Raet1e,Cpd,Adora2b,Vasn,Ldlr,Etnk1,Spint2,Ptprj,Cyth3,Fpr2,Nox1,Kctd12,Olfr56,Tmem219,H2-Ab1,Fcho2,Gpr141,Ifnar1,Il1a,Mlkl,Hspa2,Smpdl3b,Daam1,Ntng2,Igf1r,Rnd1,Marcksl1,Casp4,Slc13a3,Irs2,Fam129a,Eno2,Jak2,H2-Eb1,Prkce |
| 4.929e-12 | -26.04 | positive regulation of tumor necrosis factor superfamily cytokine production | biological process | GO:1903557 | 97 | 29 | 20694 | 1406 |
Cd14,Il18,Fzd5,Tlr1,Il12b,Mapkapk2,Lgals9,Jak2,Ifih1,Tlr3,Tlr2,Ddx58,Nod1,Nod2,Ccl2,Myd88,Spn,Tlr9,Pf4,Thbs1,Hdac1,Rasgrp1,Ptprj,Arid5a,Ptafr,Ccl4,Ccl3,Tnfrsf8,Ripk2 |
| 4.931e-12 | -26.04 | RICKMAN_METASTASIS_DN | MSigDB lists | RICKMAN_METASTASIS_DN | 231 | 52 | 15632 | 1249 |
Mndal,Gna15,Hk1,Ifi203,Ampd3,Ifi211,Ifi204,Ptgir,Cdkn1a,Ppp2r1b,Cd300lf,Rhof,Morc3,Nlrc5,I830077J02Rik,Il18bp,Ifi214,Sdc1,Mapkapk2,Tap1,Ifi207,Atp2b4,Tspo,Lad1,Tap2,Lcp2,Psd4,Txn1,Vasp,Ifi208,Il18,Ptafr,Slamf8,Ptgs2,Rnf19b,Trafd1,Keap1,Ralgds,Ifi209,Ifi205,Slc2a1,Mtus1,Psmb9,Rgs14,Slc16a3,Casp1,Spryd7,Ifi213,Pml,Prrg4,Gbp2,Myd88 |
| 5.429e-12 | -25.94 | KEGG_JAK_STAT_SIGNALING_PATHWAY | MSigDB lists | KEGG_JAK_STAT_SIGNALING_PATHWAY | 150 | 40 | 15632 | 1249 |
Ifna1,Il15,Spred1,Ifna2,Lif,Stat2,Ccnd2,Il4ra,Socs1,Spry2,Stat3,Myc,Il6,Cish,Ccnd1,Ifna5,Ifnb1,Stat5a,Pik3r5,Ifnar1,Csf3r,Jak2,Clcf1,Il15ra,Socs7,Stat1,Socs3,Il13ra1,Pim1,Pik3cd,Il2rg,Il12b,Akt3,Ifna6,Csf3,Il12rb1,Stat4,Tyk2,Il10,Osm |
| 5.436e-12 | -25.94 | Toxoplasmosis | KEGG pathways | mmu05145 | 108 | 35 | 7931 | 713 |
Il12b,H2-Eb1,Irgm1,Tab2,Ikbkg,Hspa1a,H2-Ab1,Jak2,Igtp,Myd88,Ciita,Hspa2,Birc3,Socs1,Casp3,Cycs,Il10,Ldlr,H2-Aa,Casp8,Nfkbib,Tnf,Pik3r5,Stat3,Nfkbia,Birc2,Nfkb1,Tyk2,Hspa1b,Stat1,Pik3r6,Cd40,Nos2,Akt3,Tlr2 |
| 5.436e-12 | -25.94 | Toxoplasmosis | KEGG pathways | ko05145 | 108 | 35 | 7931 | 713 |
Tab2,H2-Eb1,Irgm1,Il12b,Ciita,Hspa2,Hspa1a,Igtp,H2-Ab1,Ikbkg,Jak2,Myd88,Socs1,Birc3,Cycs,Casp3,H2-Aa,Ldlr,Il10,Casp8,Nfkbib,Tnf,Pik3r5,Birc2,Stat3,Nfkbia,Tyk2,Nfkb1,Hspa1b,Stat1,Akt3,Tlr2,Pik3r6,Cd40,Nos2 |
| 5.547e-12 | -25.92 | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | MSigDB lists | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | 64 | 25 | 15632 | 1249 |
Ddx60,Ch25h,Cx3cl1,Ifih1,Isg15,Ddx58,Lipg,Zc3hav1,Ifit1bl1,Ifit2,Ifi44,Pnp2,Oas1g,Oasl1,Herc6,Ptger4,Ifit3b,Cxcl10,Ccl5,Ifit1bl2,Daam1,Ifit3,Isg20,Oas2,Oas1a |
| 5.554e-12 | -25.92 | GSE34179_THPOK_KO_VS_WT_VA14I_NKTCELL_DN | MSigDB lists | GSE34179_THPOK_KO_VS_WT_VA14I_NKTCELL_DN | 183 | 45 | 15632 | 1249 |
Ripk3,Cd83,Zfp281,Lif,Marcksl1,Mlkl,Cish,Egr2,Stat5a,Hcar2,Clic4,Il1rn,Nr4a3,Dusp5,Cxcl2,Hk2,Csf3,Gbgt1,Golga3,Vps54,Lad1,Plek,Cdk5r1,Nmral1,Ccl22,Ccnd2,Egr1,Irf4,Fos,Nr4a1,Gadd45b,Pmepa1,Ccl4,Fscn1,Polr2g,Mthfd2,Acsl1,Trib1,C3,Denr,Egr3,Cd69,Hivep3,Irf8,Psat1 |
| 5.554e-12 | -25.92 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN | 183 | 45 | 15632 | 1249 |
Kpna3,Larp1,Ell2,Dnaja2,Il12b,Serpinb9,Gpd2,Bcl2a1a,Cflar,Il1rn,Arf4,Ldlr,Ptges,Cdkn1a,Dnajb2,Ppp2r2a,Nampt,Eno2,Map4k4,Plk2,Nos2,Casp4,Srxn1,Rab10,Stxbp3,Plscr1,Stat4,Il18rap,Traf1,Cd83,Prdx1,Hivep2,Ifit2,Slc7a11,Bcl2a1b,Acpp,Irf4,Stat3,Irgm2,Tor1aip2,Pdpn,Cnot4,Mdm2,Aebp2,Bcl2a1d |
| 5.554e-12 | -25.92 | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_UP | MSigDB lists | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_UP | 183 | 45 | 15632 | 1249 |
Hck,Rgs3,Cd38,Notch1,Gbp3,Tab2,Icam1,Fgl2,Arhgap26,Fchsd2,Gbp4,Gbp9,Ttc39c,Dse,Cst7,Parp8,Trafd1,5430427O19Rik,Plaur,Epsti1,Tnfsf10,Frmd4a,Nsmaf,Tapbpl,Usp42,Stoml1,Hopx,Ccl5,Plek,Slamf7,Rbms2,Chst11,Nlrc5,Plac8,Gfi1,Agpat4,Lyn,Irf1,Mppe1,Kctd12,Smpdl3b,Psme2,Bcorl1,Itgal,Clic5 |
| 5.554e-12 | -25.92 | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_UP | MSigDB lists | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_UP | 183 | 45 | 15632 | 1249 |
Zbp1,Ahr,Cdkn2d,Pgs1,Cpd,Il18bp,Spsb1,Mrpl52,Znrf1,Socs3,Ifi35,Zfp36,Cnn3,Srxn1,Zeb1,Fabp7,Syne2,Etv6,Birc3,Irf8,Apaf1,Prdm1,Isg15,Tab2,Zfp281,Hif1a,Icam1,Tnfsf8,Stat3,Acvr1,Txnrd1,N4bp1,Arid5a,Clic4,Ppp2r2a,Dnaja2,Larp1,Fpr1,Serpinb9,Parp12,Oas2,Sesn3,Cdyl,Vps54,Samsn1 |
| 5.555e-12 | -25.92 | PID_IL12_2PATHWAY | MSigDB lists | PID_IL12_2PATHWAY | 69 | 26 | 15632 | 1249 |
Nfkb1,Nos2,Il18rap,Tyk2,Il12rb1,Stat4,Stat1,Ripk2,Il2rg,Il18,Il12b,Ccl4,Nfkb2,Jak2,Il1b,Stat5a,H2-Q4,Gadd45b,Fos,H2-Q6,Stat3,Gadd45g,Hlx,H2-Q7,Socs1,Relb |
| 5.588e-12 | -25.91 | positive regulation of ERK1 and ERK2 cascade | biological process | GO:0070374 | 220 | 46 | 20694 | 1406 |
Scimp,Notch1,Il1b,Pdgfc,Ccl22,Cysltr2,Tlr2,Marco,Htr2b,Crkl,Map2k1,Bmp2,Fpr2,Src,Gcnt2,Rapgef2,Cflar,Ripk2,Flt1,Pdgfb,Il6,Ccl9,Cd74,C3,Pdgfrb,Htr2a,Ccl8,Icam1,Ccl5,Nod1,Nod2,Notch2,Spry2,Ccl12,Rasgrp1,Ccr1,Ccl2,Angpt1,Il1a,Ccl3,Ccl7,Cx3cl1,Glipr2,Jun,Kdr,Ccl4 |
| 5.682e-12 | -25.89 | regulation of defense response to virus by host | biological process | GO:0050691 | 42 | 19 | 20694 | 1406 |
Stat1,Ddx58,Ccl5,Aim2,Il15,Parp9,Mul1,Il12rb1,Ifna1,Zc3h12a,Dtx3l,Treml4,Il27,Cgas,Il1b,Traf3ip2,Il12b,Zc3hav1,Pml |
| 5.764e-12 | -25.88 | plasma membrane | cellular component | GO:0005886 | 5144 | 459 | 20747 | 1409 |
Cmklr1,Slc16a3,Gng12,P2ry14,Prkar2b,Myo1b,Cldnd1,Cd14,Rgs1,Jmjd6,Nod1,Nectin4,Spn,Mmp25,Mark2,Nectin2,Src,Gsr,Pde4b,Arf4,Tlr3,Xrn1,Angpt1,Gng4,Chic2,Atp2b4,Abr,Eno1,Mtus1,Myadm,Samsn1,Tnfrsf14,Slco3a1,Tmem123,Bcorl1,Slc29a3,Slc7a5,Cnp,Chmp4b,Slc2a6,Mpp7,Cdk5r1,Spry2,Casp3,Tnfsf14,Ptpn2,Selenow,Rhbdf2,Gng11,Rhou,H2-T22,Clec4d,Syne2,Tspan3,Clec5a,Cx3cr1,Flrt3,Clic4,Rtn2,Kcna3,Rnd3,Stoml1,Tmeff1,Dst,Rgs3,Itgb8,Rnf34,Cd38,Crkl,Il12rb1,Il18rap,Gpr68,Csf3r,Stxbp3,Cacnb3,Sgcb,Gramd1a,Il18,Il15ra,Sema4a,Nlgn2,Thbs1,Myd88,Piezo1,Itpr1,Pdpn,Mosmo,Bmp2,Itgav,Tulp3,Hsd17b7,Errfi1,Plaur,Gnb4,Stau1,P2ry13,Lpar1,Gypc,Gpsm2,Il13ra1,Asah2,Slc39a14,Pilrb1,Fcgr2b,Marco,Slc12a9,Clmp,Slc28a2,Rap2c,Irak3,Siglece,Traf2,Homer1,Sema4c,Kremen1,Pcdh7,Dcbld2,Adgrl2,Adap2,Mcmbp,Plpp3,Adora2a,Cd274,Tlr9,Itgal,Sema3c,Reps1,Rab10,Tmc3,Scimp,Ezr,Vezt,Prnp,Lcp2,Milr1,Cx3cl1,Irgm1,Nod2,Nfkbia,H2-T10,Dock4,Rab21,Gpr85,Slc44a1,Acvr1b,Cav1,Mfap3l,Stat3,Msr1,Tarm1,Ms4a4b,Pvr,Rras2,Rims3,Hk1,Kitl,H2-Q4,Cd74,Cd300e,Cp,Slamf7,Rhoc,Itga5,Cgas,Gja1,Ddx58,Slc30a1,Oas3,Slc31a1,Sgms2,Spire1,Tnfsf10,Ksr1,S100a8,Casp8,Cflar,Ly6c2,Enpp4,Cdc42ep2,Rab9,Irak2,Tlr1,H2-Aa,Nrp2,Carmil1,Dbnl,Ptafr,Calhm6,Clcn5,Gpr35,Plekha2,Gpr18,Kdr,S1pr2,P2ry12,Hvcn1,Zhx2,Csf1,Arl4a,Birc2,Antxr1,Il4ra,Sell,Tapbp,Kcnj2,Micall2,Fzd5,Minpp1,Treml2,Vcam1,Ehd1,Sdc1,Xcr1,Htra1,Vasp,Igsf9,Lrp8,Sipa1l1,Hcar2,Gem,Cd80,Adrb2,Pstpip2,Abcc1,Slc16a1,Katna1,Klra2,Syk,Cd200r4,Flt1,Cemip2,Rasgrp1,Crlf3,Mcoln2,Ptch1,Lnpep,Mmp14,Ptgir,Znrf3,Adgrg6,Lyn,Itga4,Spred1,Gpr132,Hk2,Rapgef2,Apba1,Lrp4,Hmox1,Flrt2,Cdc42ep4,Gpc1,Olfr56,Tmem219,Nox1,Kctd12,Il1a,H2-Ab1,Fcho2,Gpr141,Ifnar1,Irs2,Fam129a,Casp4,Marcksl1,Slc13a3,Smpdl3b,Ntng2,Daam1,Rnd1,Igf1r,Mlkl,Hspa2,Prkce,Jak2,H2-Eb1,Eno2,Ccr3,Sele,Rnf31,Agtrap,Swap70,Pdgfc,Stx11,Cpd,Adora2b,Vasn,Ripk3,Raet1e,Rab20,Fpr2,Ptprj,Cyth3,Etnk1,Spint2,Ldlr,Stra6l,Treml4,Arrdc4,Nampt,Il6,Dnajb4,Cenpj,Samhd1,Fcgr4,Ifitm1,Lratd2,Ebi3,Flnb,Cish,Scn1b,Osbpl3,Ly6a,Phlpp2,Rhoh,F11r,Acvrl1,Plpp1,Gsdmd,Fcgr1,Slc4a7,Met,Fas,Rap1gap2,Axl,Spred3,Gm5150,Rab19,Bambi,Pdgfb,Klrk1,Igsf8,Map2k1,Myo10,Ccr1,Gna15,Socs7,Plek,Adgre4,Cd40,Spata13,Fnbp1l,Pik3r5,Pdgfrb,Tapbpl,Gpr84,Hcls1,Hspa1a,Slc31a2,Pkp4,Palld,Rnf114,Cd300lf,Slc30a4,Cd69,H2-M2,Tnfsf15,Fpr1,Fzd1,P2ry2,Pik3cd,Slc48a1,Acvr1,Cd82,Agrn,Icam1,Clic5,Calcrl,Pdzd11,Tmem67,Cd200,Psd,H2-Q7,Htr2a,Prokr1,Plscr1,Tlr6,Tnfsf9,Uchl1,Rpgrip1l,Notch1,Slc7a11,Pik3r6,Abcc4,Gca,Slc39a4,Akt3,H2-Q6,H2-T24,Cpeb4,Stxbp1,Slc7a8,Cd86,Atp11a,Sphk1,Rac3,Icosl,Clec2d,Cacna1d,Cd83,Tlr2,Ptk2,Slc7a2,Htr2b,Adam19,Fgr,Mtdh,Cxcl10,Atp11b,Itga9,Cysltr2,Gbp2b,Trip10,Dcun1d3,Nos2,Notch2,Ptgs2,Ptger4,Slc9a1,Cd34,Slc2a1,Fchsd2,Ets2,Ednrb,Rffl,Mdm2,Cxcl9,Atp10a,Ly75,Rilpl1,Cd180,Acpp,Lipe,H60b,Traf5,Ccrl2,Acsl1,Xkr8,Abcb1a,Tnf,Il2rg,Phlpp1,Cd164,Bst1,Stat2,Frmd6,Pim1,Fscn1,Rhof,Olr1,Dgka,Jag1,Rhoq,Cd55,Arid4a,Hck,Lrrc8c,Rgs14,Psd4 |
| 5.872e-12 | -25.86 | anion binding | molecular function | GO:0043168 | 2674 | 273 | 20217 | 1400 |
Dennd1b,Rnf34,Plekha5,Oasl2,Acvr1,Hspa1b,Prkar2b,Ube2e1,Akt3,Scyl2,Pf4,Plekhn1,Irak2,Cyth3,Ascc3,Etnk1,Rapgef2,Gbp3,Rhoh,Ptch1,Mocs1,Ift22,Ccl2,Ccl8,Plekhf2,Kmo,Ass1,Tap1,Ccl7,Vrk2,S100a8,Nod1,Helz2,Gbp2,Tor3a,Parp14,Rasgrp1,Pde5a,Slfn9,Papss2,Ube2f,Nos2,Fabp3,Rab9,Rhof,Agrn,Stk40,Tuba4a,Smc5,Ltbp2,Flt1,Fchsd2,Samhd1,Nlrp3,Map4k4,Pdk3,Arhgap26,Rab10,Rhoc,Pim1,Sphk1,Ddx58,Gmppb,Rubcnl,Apaf1,Gclc,Trib1,Grk3,Tent4a,Gch1,Pim3,Wars,Itpkc,Stat5a,Rhoq,Tulp3,Gng12,Rab21,Gbp7,Cmpk2,P4ha2,Actb,Rab32,Srxn1,Lipg,Pde4b,Ptges,Ep400,Abcc1,Ube2e2,Egln3,Oasl1,Mitd1,Pla2g4a,Phyh,Nkiras1,Dhx58,Fabp7,Parp9,Mcm9,Mthfr,Snx2,Tent2,Acsl1,Hck,Tap2,Dync1h1,Hk1,Fgr,Pgs1,Rars,Map2k4,Met,Arl4a,Cd300lf,Gfpt1,Gbp8,Jak2,Asns,Siglece,Syk,Ripk3,Fcho2,Prkx,Layn,Mapkapk2,Acsl5,Mov10,Pdgfrb,Plek,Plcl2,Eif2ak2,Ifih1,Rab20,Mcm6,Sele,Gem,Vcan,Mark2,Gna15,Kif9,Psd,Pim2,Kif3c,Rhou,Kcnj2,Irak3,Ak4,Abcc5,Mthfd1l,Tlk2,Arf4,Gtpbp2,Rab19,Ehd1,Txnrd1,Ube2l6,Ciita,Ripk2,Clcn5,Mthfd2,Clcn7,Myo10,Cgas,Trib3,Snx10,Atp10a,Tyk2,Oas2,Kdr,Jag1,Ccl5,Map3k8,Rnd3,Hk2,Pcx,Nek6,Dnaja1,Mlkl,Ptafr,Alas1,Pnp2,Map2k1,Thbs1,Hk3,Apba1,Hspa1a,Stard5,Plk3,Prag1,Nlrc4,Myo1b,Plod3,Pgk1,Rnd1,Slfn5,Wdfy1,Ctsc,Pfkl,Acvrl1,Map3k6,Cxcl10,Ikbke,P4ha1,Rac3,Dyrk2,Irgm1,Ptk2,Atp2b4,Aida,Hcar2,Oas3,Ksr1,Pikfyve,Lpar1,Cenpe,Katna1,Dgka,Nlrc5,Sirt1,Cd34,Plk2,Atp13a1,Gsr,Dnaja2,Sik3,Atp11a,Arl5b,Prkce,Lyn,Abcb1a,Pla2g7,Ddx4,Trip13,Chd9,Nod2,Nrp2,Gsdmd,Swap70,Plod2,Atm,Hsph1,Plekha2,Pik3cd,Plekha4,Dck,Gbp9,Axl,Tgtp1,Gbp2b,Igf1r,P2ry2,Fam20c,Slfn8,Itpr1,Hspa2,Src,Arl5c,Gk,Mx1,Sesn3,Rras2,Iigp1,Hsd17b12,Hdc,Adap2,Acvr1b,Lcn2,Zcchc2,Sgk3,Rap2c,Irgq,F10 |
| 6.201e-12 | -25.81 | YAN_ESCAPE_FROM_ANOIKIS | MSigDB lists | YAN_ESCAPE_FROM_ANOIKIS | 26 | 16 | 15632 | 1249 |
Slfn4,Irf7,Nos2,Eif2ak2,Bcl2l11,Nfkb1,Ccl5,Rsad2,Stat2,Irf1,Cxcl10,Cx3cl1,Stat1,Il15,Vcam1,Slfn3 |
| 6.438e-12 | -25.77 | GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_UP | MSigDB lists | GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_UP | 177 | 44 | 15632 | 1249 |
Rap2c,Fscn1,Ifit3b,Irf1,Pim2,Oasl1,Ell2,Pou2f2,Xaf1,Oas1a,Htra1,Ifit3,Zc3hav1,Plau,Nqo1,Il6,Ikzf1,Gclm,Trip10,Sqstm1,Gadd45b,Ifit1bl1,Tnfsf10,Serpinb2,Thbs1,Kitl,Cxcl10,Phyh,Oas1g,Oas2,Vasp,Irf7,Plek,Slc7a8,Rgl1,Ifit1bl2,St3gal6,Isg15,Pml,Rsad2,Ifi44,Csf3r,Phldb1,Ifit2 |
| 6.550e-12 | -25.75 | REACTOME_SIGNALING_BY_ILS | MSigDB lists | REACTOME_SIGNALING_BY_ILS | 102 | 32 | 15632 | 1249 |
Ripk2,Socs3,Stat1,Crkl,Map2k4,Il2rg,Map3k8,Il18,Lyn,Pik3cd,Irak2,Nfkb2,Jak2,Il1rn,Il1b,Ikbkg,Map2k1,Tyk2,Il1a,Tab2,Myd88,Nod1,Hck,Irak3,Casp1,Syk,Sqstm1,Stat5a,Peli1,Il6,Stat3,Nod2 |
| 6.550e-12 | -25.75 | GO_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 102 | 32 | 15632 | 1249 |
Prkce,Nod2,Nfkbia,Tank,Birc2,Myd88,Nod1,Cd14,Tnfaip3,Irak3,Mapkapk2,Tlr6,Ddx58,Cd180,Tab2,Trim12c,Ifih1,Tlr1,Birc3,Ikbkg,Marco,Cd86,Casp8,Irf7,Tnip1,Ikbke,Irak2,Tlr3,Tlr9,Ripk2,Tnip3,Tlr2 |
| 6.567e-12 | -25.75 | catalytic activity | molecular function | GO:0003824 | 5611 | 501 | 20217 | 1400 |
Mgat1,Ccl5,Nt5c3,Usp18,Hk2,Adam19,Malt1,Adprm,Ampd3,Hk3,Hspa1a,Plpp1,Ankib1,Prag1,Rcl1,Plod3,Pgk1,Myo1b,Ctsc,Gclm,Vcam1,Parp12,Parp3,Aldh1b1,Casp1,Nampt,Cdyl2,St3gal3,Ppp2r5a,Enpp4,Znrf1,Irak3,Cnp,Ak4,Peli1,Upp1,Abcc5,Mthfd1l,Smpdl3b,Tlk2,Gtpbp2,Hmga1,Tiparp,Dio2,Dusp6,Txnrd1,Eya4,Agpat4,Birc3,Lnpep,Srm,Myo10,Nsd3,Tmtc2,Mmd,Trib3,Acpp,Dusp2,Oas2,Znrf3,Kdr,Mdm2,Asah2,Dcp2,Gm5431,Pde1b,Psmb6,St3gal6,Prdm1,Atm,Gm12185,Plat,Trim36,Inpp1,Riox2,Dck,Dusp14,Axl,Gbgt1,Tgtp1,Mx2,Degs2,Oas1b,Mid1,Slfn8,Fam20c,Sla,Hmox1,Adhfe1,Mx1,Gpd2,Rras2,Acvr1b,Trim13,Hdc,Cop1,Ust,Adgb,Ero1l,Rap2c,F10,Zc3hav1,Ext1,Psmb8,Irgm1,Dyrk2,Ptk2,Kif5c,Ksr1,Sap30,Casp7,Cp,St3gal5,Mmp14,Otud1,Prdx5,C1rl,Phgdh,Dgka,Katna1,Trim26,Cers6,Atp13a1,Lyn,Prkce,Ddx4,Pla2g7,Nod2,Noct,Tor3a,Lpcat2,Gys1,Ccnd2,Ube2f,Ggct,Hmgcs1,Nos2,Rhof,Usp31,Stk40,Tuba4a,Ptprj,Fbxo4,Htra1,Aoah,Rhoc,Pdk3,Pim1,Acod1,Gmppb,Ddx58,Casp2,Dse,Sat1,Ranbp2,Hspa1b,Pfkfb3,F830016B08Rik,Tgs1,Cycs,Trim56,Tgtp2,AA467197,Hp,Nqo1,Ascc3,Inpp5b,Rhoh,Gbp3,Ift22,Mocs1,Gm4841,Ifi47,Rabgef1,Usp53,Casp8,Tap1,Dusp1,Vrk2,Oas1a,Dtx2,Jarid2,Prdx1,Polr2g,Acp5,Fgl2,Gbp2,Nkiras1,Dtx3l,Dhx58,Ppa1,Cd38,Mthfr,Igtp,Dgkh,Acsl1,Nat2,Rnaset2a,Dync1h1,Dusp4,Hk1,Hdac1,Jak2,Gbp8,Ripk3,Cpd,Mapkapk2,Adar,Pdgfrb,Eif2ak2,Rab20,Eno1,Cdkn1a,Kif3c,Odc1,Ago3,Usp25,Gclc,Traf2,Wars,Cdyl,Pim3,Itpkc,Endod1,Rhoq,Zbp1,Gng12,Rab21,P4ha2,Prdm9,Ppm1k,Psmb10,Lipg,Nox1,Srxn1,Kdm4a,Rsad2,Pde3b,Gng11,Rnd3,Map3k8,Pcx,Nek6,Dnase1l3,Tha1,Mlkl,Ccng2,Apobec3,Alas1,Rsbn1,Pnp2,Ch25h,Map2k1,Parp8,Rnaset2b,Kat2b,Bst1,Rnf24,Plk3,Dusp16,Dusp5,Rnd1,Txn1,Il4i1,Pfkl,Cemip2,Cept1,Acvrl1,Map3k6,Ikbke,P4ha1,Birc2,Ubr4,Herc6,Smox,Pde7b,Dusp8,Rnf19a,Lap3,Oas1g,Parp10,Tnfaip3,Tut7,Pnpt1,Rab19,Ctu1,Isg20,Mul1,Ube2l6,Zup1,Ciita,Ripk2,Rffl,Mthfd2,Arel1,Plpp3,Trim30a,9930111J21Rik1,Psmb9,Cgas,Tyk2,Ccne1,Phlpp2,Ppm1l,Plod2,Tpi1,Rnf145,Pik3cd,Hat1,Gbp9,Uchl1,Casp4,Fut8,Gbp2b,Kdm6b,Igf1r,Hspa2,Src,C1ra,Rnf135,Gk,Mmp25,Sesn3,Iigp1,Hsd17b12,Usp12,Sgk3,Usp35,Mtmr14,Mmp13,Mppe1,Rac3,Gbe1,Egr2,Ldha,Trim12a,Oas3,B3gnt5,Pikfyve,Sod2,Cenpe,Rnf31,Me1,Gsta3,Dusp28,Rnf19b,Pik3r6,Rnf114,Bcor,Esd,Ifnar1,Sirt1,Plk2,Sik3,Gsr,Bmp2,Chd9,Selenow,Abcb1a,Nrp2,Dync1i2,Parp14,Lipe,Dhrs9,Sgms2,Dpy19l1,Ddhd1,Trim21,Pde5a,Ppp2r2a,Slfn9,Usb1,Fignl2,Papss2,Rab9,Casp3,Minpp1,Trim12c,Flt1,Samhd1,Map4k4,Dcp1a,Gng4,Tpst1,Rab10,Sphk1,Uba7,Oasl2,Rnf34,Acvr1,Naa25,Prkar2b,Ubash3b,Akt3,Ube2e1,Scyl2,Setdb2,Rbbp8,Irak2,Ifnb1,Psma6,Etnk1,Rnf139,Phlpp1,Hsd17b7,Rnf14,Kdm5b,Chst11,Plau,Mmp9,Ass1,Kmo,Idi1,Trmt1l,Helz2,Parp9,Mcm9,Tent2,Hck,Cdk5r1,Tap2,Xrn1,Pgm1,Zc3h12c,Fgr,Pgs1,Parp11,Map2k4,Rars,Met,Plaat3,Arl4a,Gfpt1,Asns,Jmjd6,Ciapin1,Tank,Syk,Prkx,Psat1,Acsl5,Mov10,Plcl2,Ifih1,Ccr1,Lox,Mcm6,Ppp2r1b,Eno2,Gem,Gna15,Top3a,Mark2,Kif9,Pim2,Rhou,Ccnd1,Trib1,Tet2,Vcpip1,Grk3,Gch1,Tent4a,Irgm2,Bfar,Gcnt2,Hmga2,Glrx,Acp2,Kmt5a,St3gal1,Gbp7,Ptgs2,Cmpk2,Zc3h12a,Gm4951,Gda,Med21,Gnb4,Ccnj,Extl2,Car13,Rab32,Cnot4,Ptpn2,Pigv,Arg2,Pde4b,Ep400,Rhbdf2,Ptges,Abcc1,Pdss1,Egln3,Usp42,Ube2e2,Oasl1,B4galt4,Pla2g4a,Cflar,Phyh |
| 6.795e-12 | -25.71 | GSE17721_12H_VS_24H_PAM3CSK4_BMDC_UP | MSigDB lists | GSE17721_12H_VS_24H_PAM3CSK4_BMDC_UP | 184 | 45 | 15632 | 1249 |
Ccdc25,Eef1e1,S100a8,Ifit3,Gem,Arf4,Dr1,Rbms1,Cdkn1a,Casp7,Etnk1,Ptgir,Mefv,Ifit3b,Ccl2,Myc,Gadd45b,Ppp1r14b,Rras2,Sgcb,Slc25a25,Olr1,Evl,Nek6,P2ry14,Inhba,Tbc1d13,Ccnj,Nampt,Brd2,Plk2,Atp10a,Mob3b,Cxcl10,Nr4a3,Kdm5b,Acvrl1,Dusp1,Myd88,Ube2f,Hvcn1,Prpf38a,Rhoc,Icam1,Fgr |
| 6.795e-12 | -25.71 | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_CORTICOSTERONE_TREATED_DN | MSigDB lists | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_CORTICOSTERONE_TREATED_DN | 184 | 45 | 15632 | 1249 |
Nupr1,Marcksl1,Sav1,Ripk3,Clcn5,Cd38,Ifnar1,Csf3r,Tank,Phgdh,Glipr2,Hp,St3gal1,Fpr1,Ikbke,Sec24b,Pgk1,Il1b,Phlda1,Ddit4,Mmp13,Tlr6,Nek6,Nck1,Slc16a1,Rnd3,Spred1,Ccl12,Mrpl52,Dusp2,Ncoa5,Mtmr14,Pdzd11,Mefv,Lyn,Rab20,Ldlr,Ccl4,Znrf1,Rnf14,Casp4,P2ry2,Heatr6,Etv6,Jag1 |
| 6.826e-12 | -25.71 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_UP | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_UP | 151 | 40 | 15632 | 1249 |
Scarf1,Samd9l,Rsad2,Ifrd1,Casp1,Hivep2,Tnf,Dync1h1,H2-Q4,Nlrc5,H2-Q6,Arhgef3,Psmb9,Rbm43,1600014C10Rik,Fcgr1,Tap1,H2-Q7,Rtp4,Psmb10,Ddx58,Stat2,Cd74,Psme2,Ube2l6,Trim21,Trim56,Wars,Inhba,Il12rb1,Card6,Ubr4,Serpinb2,Ppp2r2a,Plaur,Rcl1,Dusp5,Stat1,Adrb2,Usp42 |
| 6.826e-12 | -25.71 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_DN | 151 | 40 | 15632 | 1249 |
Rab21,Cycs,Nqo1,Cers6,Cox17,Acvr1,Vcan,Srm,Ezr,Ifit1bl1,Spn,Hsph1,Ptpn2,Tspo,Slc48a1,Mvp,Stxbp1,Palld,Papss2,Kdm4a,Nkiras1,Ccl22,Htra1,Trim21,Rab10,Eno2,Ifit1bl2,Abtb2,Irf7,Myo1b,Pcdh7,Zhx2,Gsta3,Parp3,Mtdh,Arid5b,Il12b,Lpar1,Chic2,Osgin2 |
| 6.938e-12 | -25.69 | phosphate-containing compound metabolic process | biological process | GO:0006796 | 1722 | 190 | 20694 | 1406 |
Ppm1k,Map3k8,Stat5a,Socs1,Eif2ak2,Mecp2,Socs3,Inpp1,St3gal1,Scyl2,Tlr9,Pgs1,Cept1,Ccng2,Il15,Dgkh,Dusp14,Rhoq,Dusp16,Ppa1,Ppp4r2,Ptk2,Kmo,Prag1,Prkx,Myc,Pde5a,Pdgfrb,Ptpn2,Ikbke,Lif,Pdgfb,Ak4,Oas1a,Flt1,Ptafr,Ampd3,Pdk3,Map2k1,Smpdl3b,Itpkc,Stat3,Hck,Src,Cycs,Pgk1,Trib1,Il12rb1,Rictor,Tyk2,Ripk3,Sphk1,Jak2,Akt3,Hk3,Inpp5b,Mdfic,Ubash3b,Plaat3,Kdr,Dusp6,Sik3,Gfpt1,Phlpp2,Eno2,Pikfyve,Nampt,Pla2g4a,Nck1,Acvrl1,Myd88,Met,Hmgcs1,Mark2,Dusp4,Ppp1r15a,Ciita,Dusp8,Saa3,Ccnd2,Acvr1b,Pgap2,Dusp1,Samhd1,Bmp2,Plk2,Grk3,Plek,Dck,Ppm1l,Ppp2r5a,Ccnd1,Cdk5r1,Prkce,Tlr3,Hk2,Itgav,Trib3,Mppe1,Mapkapk2,Acp2,Il1b,Ppp2r3a,Sla,Pim3,Mlkl,Acp5,Plpp3,Ptger4,Cnp,Ppp1r15b,Acvr1,Map2k4,Phlpp1,Pigv,Gk,Pla2g7,Papss2,Sgms2,Socs7,Cish,Mtmr14,Morc3,Sgk3,Ccr3,Irak3,Zfp36,Ripk2,Mul1,Stk40,Gpd2,Pfkfb3,Nek6,Ccne1,Cmpk2,Ptprj,Tlk2,Idi1,Dgka,Map4k4,Dyrk2,Plpp1,Pim1,Tlr2,Mocs1,Irak2,Il18,Mapkbp1,Tnf,Plk3,Stat4,Syk,Agpat4,Pml,Eya4,Ccnj,Ccl12,Pim2,Acpp,Etnk1,Ccl5,Hk1,Fgr,Vrk2,Map3k6,Igf1r,Pfkl,Dusp28,Lpcat2,Nt5c3,Mmd,Oasl2,Ksr1,Minpp1,Atm,Upp1,Acsl1,Tpi1,Ppp2r2a,Dusp2,Pik3cd,Dusp5,Plscr1,Lyn,Osm,Htr2b,Axl,Acsl5,Plcl2,Fam20c |
| 7.089e-12 | -25.67 | neutrophil chemotaxis | biological process | GO:0030593 | 74 | 25 | 20694 | 1406 |
Ccl12,S100a8,Ccl2,Trem1,Pf4,Cx3cl1,Ccl7,Ccl3,Cxcl1,Cxcl10,Ccl4,Cxcl9,Syk,Ccl9,Il1rn,Il1b,Itga9,Ccl8,Pde4b,Ccl22,Cxcl2,Cxcl11,Ccl5,Cxcl3,Csf3r |
| 7.573e-12 | -25.61 | cellular response to stress | biological process | GO:0033554 | 1434 | 165 | 20694 | 1406 |
Trib1,Tnfaip3,Pgk1,Vasn,Hmox1,Mcm10,Ripk3,Susd6,Uaca,Sphk1,Errfi1,Prdx5,Jak2,Mcm6,Rgs14,Notch1,Optn,Rnf139,Tnfrsf1b,Zc3h12a,Sesn3,Ripk2,Mul1,Parp9,Ikbke,Smc5,Wdr59,Ak4,Nek6,Ero1l,Traf2,Tfec,Lcn2,Ass1,Map2k1,Tlk2,Pdk3,Tnks1bp1,Casp4,Map4k4,Dyrk2,Bcl2a1a,Src,Bcl2l11,Asns,Dnajb2,Hmga1,Fas,Gsr,Nupr1,Dnaja1,Klf2,Trip13,Hspa2,Ptk2,Myc,Dtx3l,Zfp36,Pdgfrb,Egln3,Ascc3,Map3k8,Eif2ak2,Pnpt1,Ptger4,Tnc,Rnf34,Hspa1a,Asf1a,Map2k4,Hinfp,Ddit4,Ppp1r15b,Apaf1,Adrb2,Slc9a1,Hdac1,Batf,Slc7a11,Relb,Cav1,Lyn,Prkce,Ccnd1,Hk2,Sqstm1,Ikbkg,Casp3,Itpr1,Slc39a4,Mapkapk2,Pmaip1,Axl,Pttg1,Trim13,Trib3,Hmga2,Lrrc8c,Mdm2,Mlkl,Btg2,Mmp9,Sirt1,Slc2a1,Ier3,Bcl2a1d,Mcm9,Cflar,Fos,Ptgs2,Atm,Il6,Hif1a,Higd1a,Zbtb5,Casp2,Marf1,Samhd1,Cpeb4,Thbs1,Timeless,Hspa1b,Fam129a,Tank,Cdkn2d,Rgcc,Egr1,Vrk2,Ube2e2,Tmem67,Nox1,Parp3,Cgas,Kdm6b,Bcl6,Bnip3,Ppp1r15a,Nqo1,Sod2,Rcsd1,Jun,Fam162a,Daxx,Il1a,Ifi204,Mdfic,Tnf,Mapkbp1,Plk3,Cited2,Syk,Srxn1,Bcl2a1b,Rbbp8,Pml,Atf3,Cdkn1a,Parp10,Uba7,Eya4,Etv5,Prdx1,Nck1,Serp1,Myd88 |
| 7.617e-12 | -25.60 | regulation of vasculature development | biological process | GO:1901342 | 340 | 60 | 20694 | 1406 |
Sod2,Tcf4,Il1a,Cx3cl1,Pde3b,Vegfc,Ptger4,Mecp2,Kdr,Il10,Pml,Cx3cr1,Adrb2,Pf4,Ccl2,Col4a2,Acvrl1,Serpine1,Spry2,Rgcc,Ccl5,Egr1,Cd40,Klf2,Mtdh,Wars,C3,Ccr3,Itgb8,Cflar,Ptgs2,Lif,Spred1,Pdgfb,Hif1a,Itga5,Cxcl10,Flt1,Sema4a,Cd34,Thbs1,Plk2,Rapgef2,Stat3,Pgk1,Cysltr2,Hmox1,Hk2,Tlr3,Sphk1,Stat1,Akt3,Hmga2,Hhex,Notch1,Pik3r6,Il1b,Sirt1,Mmp9,Zc3h12a |
| 7.905e-12 | -25.56 | GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_DN | MSigDB lists | GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_DN | 178 | 44 | 15632 | 1249 |
Sdc2,Mllt6,Arhgap26,Irf4,Slfn8,Tank,Spic,Mrpl52,Pik3r5,Ifnar1,Cnn2,Ehd1,Irak3,Gbp2,Notch1,Usp18,Il1a,Itga4,Ddx60,Xaf1,Parp12,Slamf9,Flnb,Psme2,Tlr1,Gbp7,Cenpj,Rims3,Plekha2,Layn,Asah2,Mov10,Vegfc,Ppfibp2,Inpp1,Slfn9,Osbpl3,Cacna1d,Il18,Fam111a,Slc43a3,Kcna3,Ptgir,Ell2 |
| 7.905e-12 | -25.56 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_UP | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_UP | 178 | 44 | 15632 | 1249 |
Trip10,Mrpl52,Agrn,Flt1,Mmp14,Il6,Gmppb,Slamf7,Prdx1,Psat1,Rtn2,Pdss1,Ampd3,Akt3,Rcn1,Tnip3,C3,Socs3,Etnk1,Ebi3,Casp7,Ust,Cflar,Gfpt1,Fscn1,Txnrd1,Psma6,Itgb8,Crim1,Ahsa1,Batf,Txn1,Tbc1d13,Inhba,Csf3,Tnfsf15,Il12b,Ak4,Ptprj,Keap1,Stip1,Il15ra,Plat,Acsl5 |
| 8.563e-12 | -25.48 | GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 152 | 40 | 15632 | 1249 |
H2-Q6,Traf2,Ankrd17,Cd40,Tnf,H2-Q4,Ccl12,Syk,Rsad2,Dhx58,Stap1,Il6,Cd74,Fgr,Il4ra,Nlrp3,Malt1,Ddx60,H2-Q7,Hlx,Tnfrsf14,Zc3hav1,Cd80,Fzd5,Cd86,Nos2,Rabgef1,Il12rb1,Rasgrp1,Adora2b,Nr4a3,Il12b,Lyn,Ptafr,Tnfsf4,C3,Ripk2,Hmox1,Il1b,Clcf1 |
| 8.657e-12 | -25.47 | regulation of leukocyte chemotaxis | biological process | GO:0002688 | 112 | 31 | 20694 | 1406 |
Ccl2,Thbs1,Slamf8,Mtus1,Ptprj,Ccl12,Fpr2,Ccr1,Ccl4,Cxcl10,Cmklr1,Bst1,Dusp1,Vegfc,Cx3cl1,Swap70,Il1b,Lgals9,Cd74,Edn1,Stap1,Cxcl14,Csf1,Ccl5,Gpr18,Tnfsf14,Serpine1,Lyn,Sell,Nod2,Pla2g7 |
| 8.735e-12 | -25.46 | AMIT_SERUM_RESPONSE_40_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_40_MCF10A | 30 | 17 | 15632 | 1249 |
Egr1,Atf3,Fpr1,Il1a,Thbs1,Clic4,Cxcl1,Nr4a1,Nampt,Dusp1,Klf6,Jun,Cited2,Fosb,Fos,Zfp36,Cxcl2 |
| 8.934e-12 | -25.44 | GRUETZMANN_PANCREATIC_CANCER_UP | MSigDB lists | GRUETZMANN_PANCREATIC_CANCER_UP | 332 | 65 | 15632 | 1249 |
Casp1,Txnrd1,Tank,Slc2a1,Eno1,Pnp2,Acvr1,Ccng2,Gbp2,Tnfaip3,Dusp6,Lcp2,Cd86,Lad1,Pdgfrb,Serpine1,Bst1,Dgka,Spint2,Cd55,Dusp5,Oas1g,Ldha,Ptgs2,Mcm6,Il1rn,Plat,Inpp1,Plaur,Pgk1,Eif2ak2,Cyfip1,Trip10,Dnaja1,Ctsc,Vcan,Atf3,Sdc1,Prnp,Arl4a,Il4ra,Plau,Prdx1,Tspo,Gpc1,Tap1,Birc3,P4ha1,Cav1,Gem,Casp4,Lmo4,Lcn2,Plod2,Isg20,Slpi,Alas1,Ampd3,Oas1a,Mmd,Dyrk2,Stat1,Mmp9,Rcn1,Cflar |
| 9.103e-12 | -25.42 | negative regulation of kinase activity | biological process | GO:0033673 | 231 | 47 | 20694 | 1406 |
Dusp6,Ubash3b,Adora2a,Socs1,Nck1,Cdkn1a,Dusp16,Wars,Dnaja1,Prkar2b,Igf1r,Cdkn2d,Irs2,Kat2b,Spry2,Uchl1,Actb,Ptpn2,Dusp4,Aida,Gadd45g,Irak3,Gadd45b,Spred3,Dusp1,Spred1,Il6,Mvp,Dusp8,Dusp5,Fam72a,Dusp2,Ptprj,Errfi1,Casp3,Adar,Trib1,Lyn,Cav1,Tnfaip3,Ppp2r5a,Sirt1,Hhex,Il1b,Rhoh,Rgs14,Trib3 |
| 9.131e-12 | -25.42 | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 172 | 43 | 15632 | 1249 |
Icam1,Sertad3,Jmjd6,Csrnp1,Etv5,Tnfaip3,Tnfrsf8,Gys1,Eno1,Rhbdf2,Nfkbie,Bcl2a1d,Psma6,Rab21,Slc43a3,Grina,Slc31a1,Zc3h12a,Snapc1,Nfxl1,Bcl2a1a,Ppp1r15a,Serpine1,Osm,Map2k1,Hk2,Sap30,Nxf1,Nfkbiz,Tpi1,Chmp4b,Gramd1a,Nr4a1,Bcl2a1b,Ppp1r14b,Nod2,Il18bp,Il4i1,Fam162a,Tnip1,Gna15,Tnfrsf1b,Ampd3 |
| 9.185e-12 | -25.41 | positive regulation of RNA metabolic process | biological process | GO:0051254 | 1704 | 188 | 20694 | 1406 |
Nampt,Arid5a,Etv5,Zfp281,Nck1,Met,Acvrl1,Mdfic,Cx3cl1,Nlrc5,Egr2,Agrn,Kdm6b,Tra2a,Ppp1r15a,Rgcc,Egr1,Rel,Bmp2,Prdm9,Lhx2,Ciita,Jag1,Nfkb2,Il6,Hif1a,Acvr1b,Polr2g,Fubp1,Tet2,Hmga2,Il1b,Btg2,Relb,Nfkb1,Crlf3,Nr4a3,Tlr3,Ikbkg,Ifnar1,Mllt6,Maml2,Tlr9,Pf4,Nfkbia,Adrb2,Slc9a1,Med21,Batf,Spic,Stat5a,Pnpt1,Plagl1,Ell2,Mecp2,Cenpj,Arid4a,Plekhn1,Rbpms,Nr1h3,Fosb,Etv6,Zeb1,Myc,Dcp1a,Cebpd,Plagl2,Fzd5,Nupr1,Aff1,Ifrd1,Klf2,Spen,Rhoq,Birc2,Csrnp1,Stat2,Tfec,Map2k1,Hcls1,Nr3c1,Stat3,Src,Egr3,Wdr43,Lif,Pdgfb,Mafg,Zc3hav1,Nlrp3,Pou2f2,Plac8,Tnfrsf1b,Inhba,Irf7,Hmgn3,Ddx58,Maff,Tcea1,Stat1,Jak2,Pml,Atf3,Pim2,Sertad3,Taf4b,Ikzf1,Fzd1,Pcgf5,Tcf4,Jun,Ccl3,Il1a,Daxx,Tnf,Cited2,Stat4,Bambi,Cd74,Pou3f1,Arid5b,Max,Junb,Kat2b,Jmjd6,Ifnb1,Igf1r,Psip1,Cd40,Mtdh,Mycl,Dr1,Phip,Rap2c,Cd38,Hsph1,Plscr1,Fos,Ier2,Bcl9,Ahrr,Klf6,Atm,Nfil3,Casz1,Irf8,Hhex,Arf4,Sirt1,Tnip1,Ncoa7,Osm,Klf7,Ahr,Pbx1,Helz2,Lmo4,Ptch1,Il10,Nr4a1,Hinfp,Acvr1,Irf2,Hdac1,Irf1,Mov10,Ets2,Med13,Hivep3,Dtx3l,Zfp36,Irf4,Hmga1,Nod2,Nsd3,Edn1,Tnfsf8,Csf3,Hivep2,Parp9,Rnf14,Gfi1,Pid1,Notch1,Il18,Zc3h12a,Tlr2,Pim1 |
| 9.379e-12 | -25.39 | GO_REGULATION_OF_PEPTIDASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PEPTIDASE_ACTIVITY | 348 | 67 | 15632 | 1249 |
Psme1,Aim2,Pml,Rnf34,Nod1,Crim1,Apaf1,Ifi213,Tnf,Src,Casp1,Cst7,Timp1,Psmb9,Traf2,Ifi205,Ifi209,Birc2,Cycs,Casp3,Stat3,Rffl,Mdm2,Prdx5,Serpinb9,Serpinb2,Tnfsf10,Thbs1,Plaur,Serpine1,Tnfsf15,Ifi208,Spint2,Fas,Cdkn2d,Pttg1,Ifi214,Mul1,Nlrp3,Ifi207,Bcl2l11,Nlrc4,Mmp14,Il6,Myc,Ift57,Casp7,C3,Mmp9,Ifi204,Mefv,Jak2,Fam162a,S100a8,Psmb8,Birc3,Cav1,Tnfsf14,Casp8,Mndal,Ifi211,Slpi,Psme2,Sirt1,Casp2,Ifi203,Egln3 |
| 9.860e-12 | -25.34 | REACTOME_HEMOSTASIS | MSigDB lists | REACTOME_HEMOSTASIS | 437 | 78 | 15632 | 1249 |
Gnb4,Ifna2,Irf2,Fgr,Sell,F11r,Pde1b,Dock10,Mafk,Hdac1,Slc16a3,Ehd1,Src,P2ry12,Timp1,Serpinb2,Plat,Thbs1,Abcc4,Pf4,Gng12,Vegfc,Plaur,Gng4,Kif3c,Ifna6,Slc7a5,Stxbp3,Pdgfb,Dgka,Maff,Tuba4a,Plek,Slc7a8,Irf7,Serpine1,Pik3r6,Lcp2,Pde3b,Slc16a1,Gng11,F10,Plau,Kif9,Ifna1,Angpt1,Olr1,Lrp8,Prkce,Ppp2r5a,Pla2g4a,Ifna5,Pde5a,Ifnb1,Slc7a11,Syk,Itgav,Pik3r5,Spn,Dock4,Ppp2r1b,Jak2,Prkar2b,Trem1,H3f3b,Ptgir,Itga5,Dgkh,Ptk2,Lyn,Mafg,Irf1,Akt3,Rasgrp1,Nos2,Itgal,Cav1,Gna15 |
| 1.003e-11 | -25.33 | SCHOEN_NFKB_SIGNALING | MSigDB lists | SCHOEN_NFKB_SIGNALING | 34 | 18 | 15632 | 1249 |
Edn1,Jag1,Ccl12,Birc3,Nfkbia,Gadd45b,Bcl6,Tpst1,Thbs1,Cxcl1,Il1b,Mmp9,C3,Csrnp1,Hhex,Ptger4,Ptgs2,Il1a |
| 1.012e-11 | -25.32 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_DN | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_DN | 186 | 45 | 15632 | 1249 |
Batf,Myo10,Crim1,Hlx,Psma6,Txnrd1,Clic4,Plat,Keap1,Il15ra,Il2rg,Il12b,Ak4,Nrp2,Vasp,Csf3,Inhba,Txn1,Slamf7,Prdx1,Gmppb,Il6,Mmp14,Gclm,Edn1,Nqo1,Optn,Ass1,Trim36,Trip10,Fscn1,Cflar,C3,Ebi3,Casp7,Dram1,Tnip3,Pdss1,Rtn2,Akt3,Egln3,Usp12,Psat1,Sema3c,Pid1 |
| 1.022e-11 | -25.31 | kinase binding | molecular function | GO:0019900 | 797 | 108 | 20217 | 1400 |
Marcks,Ppp1r12b,Angpt1,Fas,Cdk5r1,Nck1,Slc2a1,Fgr,Map2k4,Rictor,Jak2,Syk,Stat3,Tpx2,Mapkapk2,Pdgfrb,Plek,Src,Lrp4,Cdkn2d,Cdkn1a,Stap1,Sdc4,Rhou,Cacnb3,Trib1,Ccnd1,Rac3,Mvp,Relb,Traf2,Ptk2,Irgm2,Atp2b4,Gch1,Dock4,Wars,Ksr1,Rhoq,Sipa1l1,Cenpe,Cav1,Actb,Ccnj,Ptpn2,Tax1bp1,Sirt1,Ezr,Gja1,Pde3b,Prkce,Socs1,Nod2,Irs2,Rnd3,Lipe,Spry2,Nek6,Mlkl,Gys1,Errfi1,Ccnd2,Ccng2,Ptafr,Ppp1r15a,Map2k1,Nos2,Kat2b,Rhof,Zfp36,Spred1,Tuba4a,Ptprj,Hcls1,Rgs14,Itgav,Trim12c,Cenpj,Rnd1,Pfkl,Casp1,Acvrl1,Rhoc,Klrk1,Rgcc,Nr3c1,Ppp2r5a,Hif1a,Prkar2b,Tnfaip3,Fzd5,Akt3,Bcl2l11,Stxbp1,Rffl,Sqstm1,Rapgef2,Rhoh,Nr4a3,Tnip1,Daxx,Spred3,Dusp1,Trib3,Vrk2,Dusp2,Il15ra,Ccne1 |
| 1.024e-11 | -25.30 | granulocyte chemotaxis | biological process | GO:0071621 | 81 | 26 | 20694 | 1406 |
Syk,Cxcl9,Ccl4,Cxcl10,Cxcl1,Cx3cl1,Ccl3,Ccl7,Pf4,Trem1,Ccl2,S100a8,Ccl12,Csf3r,Cxcl3,Cxcl2,Cxcl11,Ccl5,Ccl8,Pde4b,Ccl22,Itga9,Il1b,Il1rn,Ccl9,Ccr3 |
| 1.038e-11 | -25.29 | Interleukin_8-like_sf | interpro domains | IPR036048 | 37 | 18 | 19984 | 1430 |
Ccl22,Cxcl11,Cxcl10,Ccl8,Ccl7,Cxcl14,Ccl9,Ccl12,Ccl5,Cxcl1,Cxcl3,Cxcl2,Ccl2,Ccl3,Pf4,Cx3cl1,Ccl4,Cxcl9 |
| 1.038e-11 | -25.29 | Chemokine_IL8-like_dom | interpro domains | IPR001811 | 37 | 18 | 19984 | 1430 |
Cxcl10,Ccl7,Ccl8,Cxcl14,Ccl9,Ccl12,Ccl22,Cxcl11,Cxcl1,Ccl2,Cxcl2,Ccl3,Cxcl3,Pf4,Ccl4,Cx3cl1,Cxcl9,Ccl5 |
| 1.046e-11 | -25.28 | GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_DN | 166 | 42 | 15632 | 1249 |
Mcm6,Nr4a3,Cd200,Bcl2a1a,Snapc1,Gem,Med21,Sipa1l1,Tnfsf14,Dcun1d3,Ttc9c,Ccrl2,Nfkbid,Phlda1,Btg2,Arg2,Nlrp3,Mul1,Nkiras1,Egr1,Lif,Ier2,Prpf38a,Dusp14,Sla,Pfkfb3,Rnf34,Prdx1,Rras2,Bcl2a1b,Txnrd1,Gadd45b,Nr4a1,Tnf,Dusp4,Bcl2a1d,Ifrd1,Gpr35,Dusp2,Egr2,Irf4,Cycs |
| 1.053e-11 | -25.28 | regulation of peptidase activity | biological process | GO:0052547 | 443 | 71 | 20694 | 1406 |
Fam162a,Rffl,Aim2,Tnf,Serpina3g,Adora2a,Syk,Rnf34,S100a8,Psmb8,Birc3,Pml,Casp8,Nr4a1,Plaur,Hdac1,Ift57,Apaf1,Psmb9,Tnfsf10,Serpine1,Nod1,Cdkn2d,Serpinb9,Fas,Antxr1,Serpinb2,Birc2,Cst7,C3,Mefv,Myc,Mmp25,Malt1,Ripk2,Mul1,Bcl2a1d,Cflar,Tnfsf15,Ptgs2,Serpina3f,Serpinb6b,Il6,Slpi,Psme2,Casp1,Thbs1,Casp4,Stat3,Tank,Bcl2l11,Src,Hspa1b,Cycs,Cav1,Lyn,Tnfsf14,Uaca,Timp1,Stat1,Prdx5,Jak2,Nlrc4,Spint2,Pmaip1,Serpinb9b,Nlrp3,Mdm2,Sirt1,Psme1,Mmp9 |
| 1.065e-11 | -25.27 | GO_RESPONSE_TO_TUMOR_NECROSIS_FACTOR | MSigDB lists | GO_RESPONSE_TO_TUMOR_NECROSIS_FACTOR | 207 | 48 | 15632 | 1249 |
Tnfsf15,Klf2,Ccl5,Gch1,Vcam1,Ptgs2,Psmb6,Zc3h12a,Psma6,Sele,Casp3,Birc2,Cd40,Psmb9,Traf2,Tnf,Ccl3,Daxx,Tnfrsf8,Cd14,Psmb10,Icam1,Aim2,Psme1,Sirt1,Psme2,Casp8,Tnfsf14,Pid1,Nfkb1,Tnfrsf1b,Birc3,Psmb8,Ccl4,Jak2,Stat1,Tnfsf4,Il18bp,Ccl2,Il6,Edn1,Psmd10,Ass1,Ccl12,Tnfrsf14,Cx3cl1,Ccl22,Fas |
| 1.072e-11 | -25.26 | GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_DN | MSigDB lists | GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_DN | 153 | 40 | 15632 | 1249 |
Sema4a,Nr4a3,Mmp25,Cdkn1a,Adam19,Flrt2,Myo1b,Samsn1,Ppp1r15a,Plod2,Junb,Slc7a8,Dusp6,Myadm,Gja1,Ccrl2,Nfkbid,Cd69,Cxcl2,Kctd12,Pde7b,Calcrl,Prnp,Irs2,Nfkbiz,Csrnp1,Zc3hav1,Tnfaip3,Lpcat2,B4galt4,Ets2,Dusp1,Gadd45b,Nfkbia,Nr4a1,Klf6,Itgav,Lztfl1,Fgl2,Nr3c1 |
| 1.094e-11 | -25.24 | positive regulation of protein transport | biological process | GO:0051222 | 434 | 70 | 20694 | 1406 |
Cd38,Gpr68,Casp4,Cd34,Cacnb3,Clec5a,Prnp,Src,Casp1,Sec24a,Hcls1,Il6,Hif1a,Ripk2,Tnfsf15,Ptgs2,Mdm2,Clec4n,Tomm70a,Zc3h12a,Sirt1,Lgals9,Il1b,Cd274,Nlrp3,Uaca,Htr2b,Gja1,Jak2,Ifnar1,Tnfrsf14,Il4ra,Osm,Ddx58,Clec4e,Frmd4a,Cdk5r1,Prkce,Tlr2,Serp1,Ccl2,Il10,Ezr,Rasgrp1,Arid5a,Tnfsf4,Glrx,Syk,Ptger4,Vegfc,Mmp13,Cacna1d,Aim2,Plk3,Tnf,Ccl3,Adora2a,Il1a,Gsdmd,Fzd5,Cd14,Tlr1,Fgr,Nlgn2,Ifih1,Nod2,Irs2,Rgcc,Hcar2,Hk1 |
| 1.124e-11 | -25.21 | positive regulation of establishment of protein localization | biological process | GO:1904951 | 453 | 72 | 20694 | 1406 |
Hk1,Hcar2,Rgcc,Nod2,Irs2,Ifih1,Nlgn2,Fgr,Tlr1,Cd14,Fzd5,Gsdmd,Il1a,Ccl3,Adora2a,Tnf,Plk3,Aim2,Cacna1d,Cenpj,Mmp13,Ptger4,Vegfc,Syk,Glrx,Tnfsf4,Arid5a,Rasgrp1,Ezr,Il10,Serp1,Ccl2,Prkce,Tlr2,Cdk5r1,Frmd4a,Clec4e,Ddx58,Osm,Il4ra,Tnfrsf14,Ifnar1,Jak2,Htr2b,Gja1,Uaca,Nlrp3,Cd274,Il1b,Pmaip1,Lgals9,Sirt1,Zc3h12a,Tomm70a,Mdm2,Clec4n,Ptgs2,Tnfsf15,Ripk2,Hif1a,Il6,Hcls1,Sec24a,Casp1,Src,Clec5a,Prnp,Cacnb3,Cd34,Casp4,Cd38,Gpr68 |
| 1.156e-11 | -25.18 | IL8 | pfam domains | PF00048 | 37 | 18 | 18711 | 1348 |
Pf4,Cx3cl1,Cxcl14,Ccl12,Cxcl2,Cxcl9,Ccl2,Cxcl11,Ccl8,Ccl4,Ccl3,Ccl9,Ccl5,Cxcl10,Ccl7,Cxcl1,Cxcl3,Ccl22 |
| 1.160e-11 | -25.18 | protein kinase binding | molecular function | GO:0019901 | 717 | 100 | 20217 | 1400 |
Lrp4,Stap1,Cdkn2d,Cdkn1a,Rhou,Sdc4,Stat3,Syk,Pdgfrb,Tpx2,Mapkapk2,Src,Plek,Fgr,Rictor,Map2k4,Jak2,Marcks,Angpt1,Ppp1r12b,Cdk5r1,Nck1,Sirt1,Ptpn2,Gja1,Ezr,Prkce,Pde3b,Nod2,Socs1,Actb,Cav1,Ccnj,Ksr1,Rhoq,Sipa1l1,Cenpe,Ccnd1,Trib1,Cacnb3,Traf2,Ptk2,Relb,Mvp,Rac3,Dock4,Wars,Gch1,Atp2b4,Irgm2,Rhoc,Acvrl1,Rgcc,Nr3c1,Zfp36,Rgs14,Hcls1,Ptprj,Tuba4a,Spred1,Trim12c,Itgav,Rnd1,Cenpj,Ccng2,Ccnd2,Errfi1,Ppp1r15a,Ptafr,Nos2,Map2k1,Rhof,Kat2b,Irs2,Lipe,Rnd3,Nek6,Spry2,Gys1,Mlkl,Trib3,Dusp1,Vrk2,Dusp2,Ccne1,Il15ra,Sqstm1,Rapgef2,Rffl,Rhoh,Nr4a3,Spred3,Daxx,Tnip1,Bcl2l11,Stxbp1,Hif1a,Prkar2b,Akt3,Fzd5 |
| 1.173e-11 | -25.17 | negative regulation of catalytic activity | biological process | GO:0043086 | 751 | 102 | 20694 | 1406 |
Zfp36,Ptpn2,Gadd45g,Dtx3l,Irak3,Spry2,Serpine1,Birc2,Dusp16,Serpinb2,Dnaja1,Prkar2b,Plaur,Nr4a1,Birc3,Ppp1r14b,Adora2a,Serpina3g,Socs1,Rnf34,Phactr4,Atp2b4,Notch1,Rhoh,Serpinb9b,Gfi1,Rgs14,Adar,Trib1,Tnfaip3,Errfi1,Spint2,Prdx5,Timp1,Ptprj,Src,Serpinb6b,Mvp,Serpina3f,Parp9,Lrch1,Arg2,Spred1,Gadd45b,Spred3,Cd55,C3,Parp3,P2ry13,Cst7,Actb,Ppp1r15a,Nqo1,Dusp4,Aida,Serpinb9,Cdkn2d,Kat2b,Irs2,Crim1,Uchl1,Wars,Igf1r,Pml,Cdkn1a,Nck1,Tnf,Rffl,Dusp6,Ubash3b,Sh3bp4,Hhex,Il1b,Hp,Cnn3,Trib3,Mmp9,Sirt1,Mdm2,Tnfsf14,Ahr,Nfkb1,Lyn,Cav1,Ppp2r5a,F11r,Casp3,Dusp2,Marf1,Ppp1r12b,Hspa1b,Dusp5,Prnp,Fam72a,Thbs1,Dusp8,Ptgs2,Bcl2a1d,Cflar,Dusp1,Slpi,Il6 |
| 1.184e-11 | -25.16 | Apoptosis | WikiPathways | WP1254 | 83 | 33 | 4813 | 540 |
Traf1,Cycs,Tnfrsf1b,Ikbkg,Casp4,Casp3,Jun,Irf4,Birc3,Irf7,Irf1,Cflar,Traf2,Nfkbib,Map2k4,Fas,Apaf1,Tnf,Igf1r,Myc,Casp1,Mdm2,Nfkbia,Casp2,Irf2,Birc2,Bcl2l11,Pmaip1,Nfkbie,Nfkb1,Tnfsf10,Casp7,Casp8 |
| 1.185e-11 | -25.16 | GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN | MSigDB lists | GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN | 180 | 44 | 15632 | 1249 |
Hmgcs1,Sema4c,Dnajb2,Tagap,Cd82,Casp4,Mov10,Birc3,St3gal5,Pstpip2,Bcl9,Il4ra,Xrn1,Ubash3b,Etv3,Nek6,Ppfibp1,Dusp14,Tap1,Plau,Bcl2a1b,Morc3,I830077J02Rik,Il18,Map3k8,Phyh,Trafd1,Plaur,Bcl2a1a,Osm,Samsn1,Hopx,Jarid2,Socs1,Lif,Marcksl1,Rhoc,Hvcn1,Crlf3,Psmb9,Itpr1,Bcl2a1d,Stk40,Rab9 |
| 1.187e-11 | -25.16 | Fluid shear stress and atherosclerosis | KEGG pathways | ko05418 | 145 | 41 | 7931 | 713 |
Vcam1,Nox1,Il1a,Ikbkg,Nqo1,Rac3,Icam1,Il1b,Ccl12,Sdc1,Map2k4,Sdc4,Sqstm1,Fos,Ccl2,Edn1,Dusp1,Hmox1,Actb,Cav1,Mmp9,Kdr,Tnf,Sdc2,Pik3cd,Klf2,Plat,Pdgfb,Gsta3,Ptk2,Akt3,Src,Acvr1,Gpc1,Sele,Itgav,Txn1,Jun,Ass1,Nfkb1,Keap1 |
| 1.187e-11 | -25.16 | Fluid shear stress and atherosclerosis | KEGG pathways | mmu05418 | 145 | 41 | 7931 | 713 |
Nqo1,Nox1,Ikbkg,Il1a,Vcam1,Il1b,Icam1,Rac3,Ccl12,Sdc1,Sqstm1,Sdc4,Map2k4,Ccl2,Fos,Edn1,Dusp1,Mmp9,Cav1,Hmox1,Actb,Tnf,Kdr,Plat,Klf2,Pik3cd,Sdc2,Gsta3,Pdgfb,Itgav,Sele,Gpc1,Src,Acvr1,Akt3,Ptk2,Txn1,Nfkb1,Keap1,Jun,Ass1 |
| 1.187e-11 | -25.16 | GO_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | MSigDB lists | GO_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | 147 | 39 | 15632 | 1249 |
Stap1,Ifnb1,Rsad2,Spn,H2-Q4,Tnf,Ccl12,Syk,H2-Q6,Traf2,Bcl6,Cd40,Ripk3,Tap1,Abr,Malt1,H2-Q7,Icam1,Fgr,Nlrp3,Il4ra,Il12rb1,Rasgrp1,Rabgef1,Il10,Fzd5,Nos2,Pik3r6,Clcf1,Il1b,Tnfsf4,Tlr3,C3,Hmox1,Adora2b,Il12b,Ptafr,Lyn,Serpinb9 |
| 1.189e-11 | -25.16 | GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_UP | MSigDB lists | GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_UP | 160 | 41 | 15632 | 1249 |
Psmb8,Card6,Tap2,Marco,Sipa1l1,Ube2l6,H2-Aa,Psme2,Slpi,Il12rb1,Wars,Hivep3,H2-Ab1,Slc31a1,Stat1,Irf1,Ptgs2,Slamf8,Clec5a,Mmp25,Vcam1,Bcl2a1a,Tnf,Nlrc5,Bcl2a1b,Casp1,Psmb9,Tiparp,Parp14,Oaf,Pnp2,Rsad2,Bcl2a1d,Samd9l,Ier2,Cd74,Stat2,Ccnd2,Gbp3,Rtp4,Gbp2 |
| 1.216e-11 | -25.13 | GO_CYTOKINE_PRODUCTION | MSigDB lists | GO_CYTOKINE_PRODUCTION | 110 | 33 | 15632 | 1249 |
Il1b,Trem1,Pik3cd,Azi2,Lyn,Ptafr,Il18,Tlr2,Il12b,Ptgs2,Tnfsf4,Tlr9,Cd55,Rasgrp1,Trim56,Sirt1,Nos2,Irf7,Lcp2,S100a8,Notch1,Nod1,Batf,Nlrp3,Hif1a,Tlr6,Aim2,Nod2,Pnp2,Dennd1b,Nlrc4,Ifnar1,Casp1 |
| 1.232e-11 | -25.12 | GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_UP | MSigDB lists | GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_UP | 187 | 45 | 15632 | 1249 |
Slc7a2,Cnp,Stxbp3,Gpr132,Rab10,Adora2b,Fndc3a,Dnaja2,Hp,Ptges,Tcea1,Txnrd1,Abcc5,Prdx5,Tapbp,Agtrap,Prdm1,Cd38,Nos2,Zc3h12c,Ubr4,Tor3a,Alas1,Fabp7,Cacnb3,Irf1,Cd200,C3,Gsta3,Abcc1,Dnajb2,Esd,Asf1a,Clcn7,Ass1,Spsb1,Nqo1,Cxcl14,S1pr2,Gbe1,Trim13,Usp25,Tap1,Olr1,Prdx1 |
| 1.232e-11 | -25.12 | GSE17721_POLYIC_VS_CPG_6H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_6H_BMDC_UP | 187 | 45 | 15632 | 1249 |
Rap2c,Inpp1,Asf1a,Nfil3,Lhx2,Fam53c,Mcm6,Chic2,Wdfy1,Spen,Bcl9,Spint2,Oas2,Snx2,Sesn3,Brwd3,Ankib1,Cep350,Plekha2,Casp8,Ptch1,Fcgr1,Mvp,Rab3ip,Stxbp1,Mthfr,Sphk1,Xrn1,Fgr,Aftph,Ctsc,Rin2,Acvr1,Kdm5b,Mafk,Psip1,Phldb1,Plekhf2,Morc3,Parp8,Spsb1,Birc2,Gpsm2,Homer1,Rgs14 |
| 1.232e-11 | -25.12 | GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP | 187 | 45 | 15632 | 1249 |
Cd302,Dusp1,Egr2,Rab19,Ier2,Plk3,Irak3,Tnfaip3,Gda,Fosb,Ppp1r15a,Cd274,Junb,Maff,Nfkbid,Arl5b,Map3k8,Phf6,Dusp5,Ptger4,Prkx,Pilrb1,Dnaja1,Fos,Sbds,Nr4a1,Dusp2,P2ry14,Arrdc4,Cdk5r1,Etv3,Egr1,Nfkbiz,Pim3,Pilrb2,Gem,Plekhg1,Ppp1r15b,Cd69,Zfp36,Adrb2,Trib1,Filip1l,Gfi1,Ccl4 |
| 1.238e-11 | -25.11 | GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 835 | 123 | 15632 | 1249 |
Agrn,Bcl2l11,Ccl12,Flt1,Dock4,Jun,Myc,Ccl2,Prkce,Abr,Nlrp3,Ccl22,Htr2a,Cdc42ep2,Angpt1,Rabgef1,Gna15,Plscr1,Casp2,Rasgrp1,Ifi203,Sirt1,Casp7,Mefv,Adrb2,Rgs1,Tagap,Casp1,Ifi213,Cd40,Ifi205,Rgs14,P2ry12,Dennd1b,Tbc1d1,Casp3,Pml,Psme1,Icam1,Spata13,Ahsa1,Bmp2,Nod1,Rhoc,Ripk3,Rgl1,Sipa1l1,Ifi208,Tnfsf15,Inpp5b,Pdgfb,Ptafr,Tnfsf10,Elmod2,Tcea1,Rapgef5,Trip10,Nlrc4,Mmp14,Tor1aip2,Ift57,Psd,Rin2,Nck1,Fas,Irs2,Nr1h3,Mul1,Ifi214,Cx3cl1,Cyth3,Ifi207,S100a8,Adap2,Mndal,Casp8,Cav1,Plekhg1,Psme2,Ifi211,Egln3,Rap1gap2,Dennd2a,Ptgir,Ptk2,Ifi204,Lpar1,Ccl4,Arf4,Jak2,Fam162a,Tnf,Ifi209,Traf2,Arhgef3,Stat3,Cycs,Dock10,Hspa2,Sele,Errfi1,Arhgap26,Asap3,Aim2,F11r,Ccl3,Rgs3,Apaf1,Rab3ip,Ccl5,Psd4,Plek,Pdgfrb,Ppp1r15a,Tor1aip1,Tbc1d13,Rapgef2,Cdc42ep4,Il2rg,Kitl,Ralgds,Htr2b,Pkp4 |
| 1.239e-11 | -25.11 | tube development | biological process | GO:0035295 | 931 | 119 | 20694 | 1406 |
Hlx,Stk40,Spred1,Lif,Pdgfb,Mthfr,Flt1,Arg2,Vcan,Ptprj,Ldlr,Map2k1,Sema3c,Nr3c1,Egr3,Bcl2l11,Src,Hmox1,Crkl,Gsta3,Stat1,Spint2,Errfi1,Foxp4,Notch1,Tiparp,Zc3h12a,Il18,Mthfd1l,Pdpn,Hopx,Vegfc,Phactr4,Ptger4,Tulp3,Tnc,Nr4a1,Intu,Acvr1,Apaf1,Plau,Ccl2,Spry2,Col18a1,Csf1,Klf2,Edn1,Sema4c,Ptk2,Mmp14,Sav1,Itgb8,Prkx,Kdm5b,Zeb1,Ccr3,Myc,Pdgfrb,Fzd5,Vasp,Ptgs2,Phgdh,Lox,Jag1,Hif1a,Sema4a,Bmp2,Nrp2,Timeless,Thbs1,Lhx2,Cav1,Slc7a11,Pbx1,Ahr,Nr4a3,Gja1,Ptch1,Cemip2,Lmo4,Itgav,Casp3,Gpsm2,Pik3r6,Hmga2,Hhex,Clmp,Pdgfc,Sirt1,Jun,Fzd1,Cx3cl1,Pde3b,Syk,Cited2,Kdr,Pml,Casp8,Ccl12,Sdc4,Ift57,Prdm1,Acvrl1,Col4a2,Angpt1,Met,Calcrl,Notch2,Jmjd6,Clic4,Nox1,Wars,Tmem67,Tnfaip2,Rpgrip1l,Plod3,Sec24b,Ednrb,Junb |
| 1.300e-11 | -25.07 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | 141 | 38 | 15632 | 1249 |
Azi2,Tlr2,Trib1,Smc5,Nfil3,Gfi1,Glrx,Rbms1,Fosb,Sik3,Sipa1l1,Klf2,Slc31a2,Rap1gap2,Jag1,St3gal5,Zfp36,Sap30,Spen,Dmxl2,Arl4a,Irs2,Plagl1,Atp2b4,Pde3b,Jun,Cited2,Tank,Timp1,Fos,Plekha5,Klf6,Dusp1,Nfkbia,Cebpd,Chst11,Ly75,Spry2 |
| 1.358e-11 | -25.02 | negative regulation of response to biotic stimulus | biological process | GO:0002832 | 88 | 27 | 20694 | 1406 |
Fgl2,Ptpn2,Irak3,Tap1,Clec2d,Dhx58,Lgals9,Acod1,Tap2,Adar,Serpinb9,Tnfaip3,Trib1,Nfkbil1,Prdm1,Smpdl3b,Slamf8,Samhd1,Trafd1,Nmi,Parp14,Ccr1,Arg2,Htra1,Nlrc5,Mapkbp1,Mul1 |
| 1.379e-11 | -25.01 | GSE19401_UNSTIM_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_UNSTIM_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN | 174 | 43 | 15632 | 1249 |
Nfkb1,Gem,Stat4,Cflar,Fscn1,Tnfaip2,Ccl4,Tnip1,Nfkbia,Hmga1,Scarf1,Gadd45g,Nqo1,Atf3,Sdc4,Cdc42ep2,Cd80,Junb,Ccl5,Lad1,Serpine1,Icosl,Slc7a5,Adora2a,Serpinb9,Vcam1,Thbs1,Nfkb2,Il15ra,Il1b,Tnf,Ehd1,Gypc,Slc16a3,Cd40,Marcksl1,Sell,Traf1,Cd83,Hck,Tnfaip3,Plagl2,Relb |
| 1.379e-11 | -25.01 | GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_UP | MSigDB lists | GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_UP | 174 | 43 | 15632 | 1249 |
F11r,Upp1,Il1a,Pigv,Stau1,Ncoa7,Hivep2,Flt1,Bcl2a1b,Casp1,Arhgef3,Rbbp8,Pnp2,Kremen1,Errfi1,Rsad2,Bcl2a1d,Gpr68,Cd55,St3gal1,Stat1,Dusp5,C3,Acvr1b,Ptgs2,Cxcl1,Bcl2a1a,Cldnd1,Cd82,Serpinb2,Fmnl2,Plaur,Rcl1,Gng12,Il1b,Card6,Pid1,Reps1,Trim21,Htra1,Met,Hk2,Cxcl2 |
| 1.427e-11 | -24.97 | positive regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050731 | 194 | 42 | 20694 | 1406 |
Jak2,Stap1,Cd40,Ccl5,Lrp8,Icam1,Clcf1,Il15,Tnfrsf14,Lyn,Nod2,Rictor,Osm,Il18,Htr2a,Agrn,Il12b,Cd74,Itga5,Il6,Plpp3,Syk,Lif,Ptger4,Vegfc,Pdgfb,Cd80,Tnf,Kitl,Lrp4,Parp9,Ripk2,Prnp,Angpt1,Csf3,Src,Hdac1,Fcgr1,Hsph1,Ptprj,Hcls1,Parp14 |
| 1.447e-11 | -24.96 | GSE19888_ADENOSINE_A3R_INH_VS_INH_PRETREAT_AND_ACT_WITH_TCELL_MEMBRANES_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_VS_INH_PRETREAT_AND_ACT_WITH_TCELL_MEMBRANES_MAST_CELL_UP | 181 | 44 | 15632 | 1249 |
Il15,Rtp4,Irgm2,Parp14,Pdpn,Samd9l,Rab32,Tagap,Ms4a6d,Irf1,Akt3,Oas1a,Tor3a,Irf8,Casp4,Gbp7,Ifit1,Hck,Magohb,Mthfr,Nupr1,Ddx58,Usp18,Stat2,Gbp3,Isg15,Dtx3l,Gbp9,Gbp4,Ogfrl1,Rsad2,Casp1,Ifnar1,Clmp,P2ry13,Snapc1,Oas1g,Fndc3a,Ext1,Wdfy1,Trim26,Oas2,Parp12,Samsn1 |
| 1.447e-11 | -24.96 | GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN | 181 | 44 | 15632 | 1249 |
Ksr1,Inpp5b,Csf1,Tlr1,Ube2e2,Stx11,Vasp,Etv6,Tmem176a,Hopx,Vps54,Fubp1,Sipa1l1,Snapc1,Cldnd1,Mitd1,Stip1,Ldha,Ppa1,Map3k8,Sema4a,Parp14,Ctsc,Stat3,Myc,Glipr2,Samd9l,Hsph1,Dnaja1,Bcl6,Tiparp,Slc2a1,Myd88,Tnfrsf8,Samhd1,Hlx,Prdm1,Mxd1,Stat2,Hif1a,P2ry14,Gmppb,Il4ra,Socs1 |
| 1.482e-11 | -24.93 | positive regulation of nucleic acid-templated transcription | biological process | GO:1903508 | 1608 | 179 | 20694 | 1406 |
Stat3,Src,Egr3,Nr3c1,Map2k1,Hcls1,Tfec,Stat2,Mafg,Lif,Pdgfb,Wdr43,Pou2f2,Plac8,Nlrp3,Stat1,Jak2,Tcea1,Hmgn3,Ddx58,Maff,Inhba,Irf7,Batf,Spic,Pf4,Tlr9,Nfkbia,Adrb2,Slc9a1,Med21,Mllt6,Maml2,Cenpj,Arid4a,Rbpms,Mecp2,Plagl1,Ell2,Stat5a,Dcp1a,Plagl2,Cebpd,Fzd5,Myc,Nr1h3,Fosb,Etv6,Zeb1,Rhoq,Birc2,Csrnp1,Klf2,Ifrd1,Spen,Nupr1,Aff1,Prdm9,Lhx2,Bmp2,Rel,Acvr1b,Hif1a,Nfkb2,Il6,Jag1,Ciita,Hmga2,Il1b,Fubp1,Tet2,Ikbkg,Ifnar1,Tlr3,Nr4a3,Relb,Nfkb1,Crlf3,Met,Acvrl1,Nck1,Zfp281,Arid5a,Etv5,Nampt,Egr2,Nlrc5,Mdfic,Cx3cl1,Ppp1r15a,Agrn,Kdm6b,Rgcc,Egr1,Csf3,Hivep2,Tnfsf8,Rnf14,Parp9,Il18,Zc3h12a,Notch1,Gfi1,Pid1,Tlr2,Pim1,Irf1,Hdac1,Nr4a1,Hinfp,Acvr1,Irf2,Il10,Ets2,Irf4,Dtx3l,Hivep3,Med13,Edn1,Nsd3,Hmga1,Nod2,Plscr1,Cd38,Hsph1,Rap2c,Casz1,Klf6,Atm,Nfil3,Ahrr,Fos,Ier2,Bcl9,Sirt1,Arf4,Hhex,Irf8,Ptch1,Lmo4,Helz2,Ahr,Pbx1,Ncoa7,Tnip1,Osm,Klf7,Ikzf1,Pim2,Taf4b,Sertad3,Pml,Atf3,Bambi,Cited2,Stat4,Ccl3,Daxx,Il1a,Tnf,Fzd1,Pcgf5,Tcf4,Jun,Junb,Arid5b,Max,Cd74,Pou3f1,Dr1,Phip,Igf1r,Cd40,Psip1,Mtdh,Mycl,Kat2b,Jmjd6,Ifnb1 |
| 1.522e-11 | -24.91 | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | 449 | 79 | 15632 | 1249 |
Tlk2,Mecp2,Acvr1,Cers6,Fut8,Mdn1,Nr3c1,Fchsd2,Homer1,Swap70,Ankrd17,Klf6,Dusp1,Crim1,Myo10,Tab2,Rapgef2,Ppp2r3a,Ext1,Phlpp2,Myo1b,Flrt2,Serpine1,Fubp1,Map2k1,Ascc3,Cdyl,Slc4a7,Jarid2,Vegfc,Pkp4,Sec24b,Ppp2r2a,Zhx2,Sec24a,Arid5b,Smc5,Fndc3a,Rin2,Ifrd1,Phlpp1,4932438A13Rik,Cnot4,Mid1,Myc,Bbx,Jun,Tiparp,Ptpn2,Cenpe,Hivep2,Klf7,Aff1,Atp11b,Rras2,Phip,Gbe1,Pikfyve,Nck1,Usp12,Tdrd7,Zeb1,Spen,Flnb,Med13,Sema3c,Cep350,Casp8,Sik3,Wdr43,Rbms1,Ldlr,Chd9,Lyn,Map2k4,Kpna3,Ptk2,Filip1l,Kif5c |
| 1.562e-11 | -24.88 | positive regulation of RNA biosynthetic process | biological process | GO:1902680 | 1609 | 179 | 20694 | 1406 |
Pim1,Tlr2,Pid1,Gfi1,Notch1,Zc3h12a,Il18,Parp9,Rnf14,Tnfsf8,Hivep2,Csf3,Nod2,Hmga1,Nsd3,Edn1,Hivep3,Med13,Dtx3l,Irf4,Ets2,Il10,Nr4a1,Acvr1,Hinfp,Irf2,Hdac1,Irf1,Klf7,Tnip1,Ncoa7,Osm,Ahr,Pbx1,Helz2,Lmo4,Ptch1,Irf8,Hhex,Arf4,Sirt1,Bcl9,Fos,Ier2,Ahrr,Atm,Nfil3,Klf6,Casz1,Rap2c,Cd38,Hsph1,Plscr1,Jmjd6,Kat2b,Ifnb1,Mtdh,Mycl,Igf1r,Cd40,Psip1,Phip,Dr1,Cd74,Pou3f1,Max,Arid5b,Junb,Tcf4,Pcgf5,Jun,Fzd1,Tnf,Ccl3,Daxx,Il1a,Stat4,Cited2,Bambi,Atf3,Pml,Pim2,Sertad3,Taf4b,Ikzf1,Inhba,Irf7,Maff,Ddx58,Hmgn3,Tcea1,Stat1,Jak2,Nlrp3,Plac8,Pou2f2,Wdr43,Lif,Pdgfb,Mafg,Stat2,Tfec,Hcls1,Map2k1,Nr3c1,Egr3,Stat3,Src,Nupr1,Aff1,Spen,Ifrd1,Klf2,Csrnp1,Rhoq,Birc2,Zeb1,Fosb,Etv6,Nr1h3,Myc,Plagl2,Cebpd,Dcp1a,Fzd5,Stat5a,Ell2,Plagl1,Mecp2,Rbpms,Cenpj,Arid4a,Maml2,Mllt6,Slc9a1,Med21,Tlr9,Nfkbia,Adrb2,Pf4,Spic,Batf,Crlf3,Relb,Nfkb1,Nr4a3,Tlr3,Ikbkg,Ifnar1,Fubp1,Tet2,Il1b,Hmga2,Ciita,Jag1,Il6,Nfkb2,Acvr1b,Hif1a,Rel,Bmp2,Lhx2,Prdm9,Egr1,Rgcc,Agrn,Kdm6b,Ppp1r15a,Cx3cl1,Mdfic,Nlrc5,Egr2,Nampt,Arid5a,Etv5,Nck1,Zfp281,Acvrl1,Met |
| 1.593e-11 | -24.86 | GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_DN | 168 | 42 | 15632 | 1249 |
Fcgr4,Pdk3,Nampt,Htra1,Ccrl2,Prdm9,Dram1,Slc31a1,Ptgs2,Mppe1,Lyn,Fpr1,Acsl1,Cdc42ep4,Rab20,Bcl2a1a,Bambi,Gca,Tnfsf10,Lhx2,Trem1,Il1b,Socs7,Rab32,Bcl2a1b,Dhrs9,Slc16a3,Sod2,Slc7a11,Sat1,Kcnj2,Prkce,Sdc2,Fgl2,Treml2,Bcl2a1d,Cebpd,Fas,Tlr6,Lif,Apba1,Dnase1l3 |
| 1.764e-11 | -24.76 | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 182 | 44 | 15632 | 1249 |
Gadd45b,Nfkbia,Nr4a1,Edn1,Gpr35,Tpi1,Chmp4b,Olr1,Gna15,Birc3,Rabgef1,Ppp1r15b,Cd69,Trib1,Hmgcs1,Ell2,Rbbp8,Kdm5b,Nfkbie,Psma6,Rab21,Rab9,Icam1,Sertad3,Malt1,Lif,Irak3,Tnfaip3,Serpine1,Map2k1,Osm,G3bp2,Arl5b,Ak4,Slc43a3,Grina,Nr4a3,Ptger4,Scyl2,Zhx2,Cxcl1,Gtpbp2,Irak2,Cldnd1 |
| 1.764e-11 | -24.76 | GSE6674_ANTI_IGM_VS_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_ANTI_IGM_VS_CPG_STIM_BCELL_DN | 182 | 44 | 15632 | 1249 |
Atf3,Lrp8,Lif,Csrnp1,Gmppb,Arl4a,Il4ra,Socs1,Spred1,Tnf,Txnrd1,Srm,Arid5a,Irf4,Ccdc86,Myc,Cish,Taf4b,Gadd45g,Larp1,Ptger4,Rnf19b,Rcn1,Pim1,Map3k8,Spata5l1,Ppp2r1b,Rgs1,Sec24a,Slc37a3,Frmd6,Wdr43,Hsd17b7,Cdkn1a,Cdyl,Slc4a7,Tuba4a,Dcun1d3,Rrs1,Casp8,Osm,Noc4l,Eef1e1,Hk2 |
| 1.796e-11 | -24.74 | Cytosolic DNA-sensing pathway | KEGG pathways | ko04623 | 61 | 25 | 7931 | 713 |
Ikbkg,Ifna4,Cgas,Il6,Ripk3,Il1b,Zbp1,Ifna6,Ccl5,Adar,Ifnb1,Il18,Aim2,Nfkbia,Ifna5,Irf7,Nfkbib,Casp1,Cxcl10,Ikbke,Ccl4,Ddx58,Ifna1,Nfkb1,Ifna2 |
| 1.796e-11 | -24.74 | Cytosolic DNA-sensing pathway | KEGG pathways | mmu04623 | 61 | 25 | 7931 | 713 |
Ikbkg,Ifna4,Il6,Cgas,Ripk3,Il1b,Zbp1,Ifna6,Ccl5,Adar,Ifnb1,Il18,Aim2,Nfkbia,Ifna5,Irf7,Casp1,Nfkbib,Cxcl10,Ikbke,Ccl4,Ddx58,Ifna1,Nfkb1,Ifna2 |
| 1.816e-11 | -24.73 | GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_DN | 189 | 45 | 15632 | 1249 |
Rcsd1,Mefv,Odc1,Fam162a,Tnfrsf1b,Zc3h12c,Csf1,Etv6,Rasgrp1,Stx6,Rnf19a,Irs2,P2ry14,Clec4e,Rnd3,Rbl1,Olr1,Nfkbia,Ets2,Ccl2,Cxcl10,Arid5b,Map3k8,Il1rn,Hcar2,Dusp6,Junb,Pde4b,Map2k1,Ppp1r15a,Maff,Inhba,Prdm1,Ier2,Gbp3,Cd38,Ddhd1,Hsph1,Bcl6,Itpr1,Arhgef3,Pnp2,Ccng2,Mecp2,Errfi1 |
| 1.816e-11 | -24.73 | GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_DN | 189 | 45 | 15632 | 1249 |
Igsf6,Ccl2,Vcan,Palld,Atf3,Clec4e,Rnd3,Olr1,Birc3,Marco,Irf8,Plscr1,St3gal5,Tdrd7,Rnf19a,Mefv,Cflar,Fscn1,Cdkn1a,Frmd6,Dusp16,Stat5a,Hsph1,Csf3r,Arid5a,Stat3,Stk40,Errfi1,Icam1,Spata13,Brd2,Gch1,Pde4b,Myo1b,Slfn4,Rilpl1,Btg2,Fam53c,St3gal1,Map3k8,Osgin2,Rcan1,Ralgds,Slfn3,Hcar2 |
| 1.830e-11 | -24.72 | WINZEN_DEGRADED_VIA_KHSRP | MSigDB lists | WINZEN_DEGRADED_VIA_KHSRP | 94 | 30 | 15632 | 1249 |
Nfkbiz,F11r,Bmp2,Sdc4,Pdgfc,Ifit1bl1,Tnf,Ifit2,Il6,Edn1,Spry2,Sdc2,Sele,Errfi1,Dusp5,Cpeb4,Ptger4,Adrb2,Cxcl10,Ptgs2,Cxcl1,Plaur,Gdf15,Dusp6,Ifit1bl2,Gem,Zfp36,Cxcl2,Jag1,Inhba |
| 1.845e-11 | -24.72 | GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN | 196 | 46 | 15632 | 1249 |
Il15ra,Ptges,Slc29a3,Serpinb9,Nr4a3,Ptger4,Gng4,AA467197,Tmeff1,Ppp1r15a,Plek,Mdfic,Lipg,Ier2,Malt1,Plk3,H2-Q7,Csrnp1,D1Ertd622e,Sat1,Egr2,Slc15a3,Ly75,H2-Q6,Cst7,Tagap,Lrrc8c,Gfi1,Jak2,Rab20,Il13ra1,Tnfsf14,Vezt,Casp4,Ahr,Dusp14,Pim3,Ubash3b,Plagl1,Atf3,Egr1,Chst11,Dusp4,Tiparp,H2-Q4,Itgav |
| 1.888e-11 | -24.69 | positive regulation of leukocyte proliferation | biological process | GO:0070665 | 143 | 35 | 20694 | 1406 |
Cd86,Tnfsf4,Cdkn1a,Tnfsf9,Peli1,Icosl,Myd88,Nck1,Cd38,Spn,Tlr9,Ripk2,Kitl,Stat5a,Bst1,Il6,Cd80,Syk,Il1b,Il12b,Cd274,Ccdc88b,Cd74,Itgal,Il18,Bcl6,Csf1,Ccl5,Il15,Clcf1,Lyn,Il12rb1,Irs2,Vcam1,Cd40 |
| 1.911e-11 | -24.68 | PID_IL23_PATHWAY | MSigDB lists | PID_IL23_PATHWAY | 35 | 18 | 15632 | 1249 |
Il18,Il12b,Socs3,Stat1,Il1b,Jak2,Nos2,Nfkb1,Ccl12,Stat5a,Tnf,Nfkbia,Il18rap,Tyk2,Il12rb1,Stat4,Il6,Stat3 |
| 1.913e-11 | -24.68 | neutrophil migration | biological process | GO:1990266 | 83 | 26 | 20694 | 1406 |
Cxcl1,Cx3cl1,Ccl3,Ccl7,Mcoln2,Cxcl9,Syk,Ccl4,Cxcl10,S100a8,Ccl12,Pf4,Trem1,Ccl2,Cxcl3,Cxcl2,Cxcl11,Ccl5,Csf3r,Il1rn,Ccl9,Il1b,Ccl8,Pde4b,Ccl22,Itga9 |
| 1.913e-11 | -24.68 | T cell activation | biological process | GO:0042110 | 269 | 51 | 20694 | 1406 |
Il12b,Cd74,Treml2,Fzd5,Ptpn2,Malt1,Irf4,Psmb10,Gadd45g,Egr1,Fas,Icam1,Il15,Jmjd6,Ifnb1,Tnfsf4,Batf,Irf1,Ikzf1,Ifna6,Nck1,Rsad2,Stat5a,Ifna2,Azi2,Syk,Ptger4,Rhoh,Itgal,Ifna1,Fgl2,Gpr18,Clec4e,Ripk3,Clec4d,Relb,Gja1,Itgav,Ifnar1,Tnfsf8,Stx11,Sema4a,Stat3,Icosl,Spn,Ripk2,Bcl2a1d,Ifna4,Ifna5,Il6,Ebi3 |
| 1.938e-11 | -24.67 | localization | biological process | GO:0051179 | 4605 | 416 | 20694 | 1406 |
Mmp14,Ccr3,Rhoc,Svbp,Itga4,Dtx3l,Hvcn1,Frmd6,Rubcnl,Dnaja1,Socs7,Stau1,Sema4c,Edn1,Rab21,Cnp,Cx3cr1,Tspo,Fchsd2,Rab11fip1,Kif3c,Hspa1a,Cenpe,Sele,Trip10,Scarf1,Chmp4b,Tomm70a,Sbds,Fam53c,Marcksl1,Nfkbib,Slc31a1,Marco,Casp1,Micall2,Pvr,Hap1,Rrs1,Ldlr,Lrp4,Mul1,Rhbdf2,Slc29a3,Rilpl1,Parp3,Tnfaip2,Tbc1d1,Arid5b,Slc25a12,Insl6,Fscn1,Lipg,Jmjd6,Uchl1,Slc16a1,Icam1,Hk1,Atp13a1,Nlgn2,Dync1h1,Arl5b,Igf2bp2,Dennd2a,Rasgrp1,Ccl12,Slc13a3,Pstpip2,Angpt1,Ikzf1,Daxx,Tnf,Osbpl3,Stxbp1,Bambi,Lgals9,Cd274,Ccl22,Slc2a1,Cav1,Spire1,Slc31a2,Cxcl11,Myadm,Tbc1d13,Dbnl,Sqstm1,Samd9l,Itpr1,F11r,Slc25a37,Spn,Pik3cd,Rapgef2,Plscr1,Ier2,Reps1,Syne2,Stard7,Anp32a,Kpna3,Ddx4,Ptk2,Slc25a22,Rab3ip,Nr1h3,Prag1,Rac3,Ch25h,Prkx,Ccl8,Pdgfrb,Hspa2,Tor1aip1,Antxr1,Rhoq,Stx6,D1Ertd622e,Nfkbia,Adrb2,Arrdc4,Slc30a1,Stard5,Slamf8,Ccl2,Stat5a,Pnpt1,Pdpn,Kif5c,Gramd1a,Rgs14,Nlrp3,Orai2,Itga9,Inhba,Tnfaip3,Rab19,Lrp11,Tlr6,Lcp2,Snx10,Fpr2,Map2k1,Ly75,Tmc3,Nxf1,Treml4,Bcl2l11,Aftph,Kcna3,Gpc1,Slc25a25,Vcan,Flt1,Ccdc88b,Slc28a2,Il12b,Agrn,Traf3ip2,Bnip3,Cd14,Ednrb,Slc7a5,Slc37a3,Srgn,Chic2,Clic4,Stxbp3,Mfsd7a,Spata13,Pikfyve,Cdkn1a,Sdc4,Abcc1,Pla2g4a,Katna1,Etv5,Cp,Nck1,Fnbp1l,Acvrl1,Gpr35,Stra6l,Inpp5b,Rffl,P2ry12,Slc16a3,Pmaip1,Isg15,Slc39a14,Il1b,Lrrc8c,Slc15a3,Keap1,Cdk5r1,Slc30a4,Plat,Nrp2,Plek,Mcm9,Lox,Mid1,Saa3,Pgap2,G3bp2,Morc3,Nectin2,Itgb8,Clic5,Slc12a9,Zfp36,Nod2,Tmsb10,Carmil1,Tap2,Lrp8,Homer1,S100a8,Xkr8,Nr4a1,Acvr1,Hinfp,Clcn7,Plau,Ehd1,Aim2,Atp2b4,Mcoln2,Abcb1a,Plekhf2,Notch1,Cd302,Itgal,Tlr2,Xcr1,Stx11,Nfkbie,Myo1b,Cyth3,Nos2,Cxcl9,Atp10a,Scn1b,Cd74,Fabp3,Ift22,Pde4b,Sec24b,Actb,Malt1,Ccl5,Rabgef1,Cxcl2,Phip,Nox1,Msr1,Pml,Slc44a1,Ccr1,Arl5c,Milr1,Rab20,Fcho2,Snx2,Ccl3,Syk,Sh3bp4,Ric1,Ccl4,Axl,Irf8,Acsl5,Gpsm2,Tap1,Hhex,Arf4,Ier3,Slc7a11,Chst11,Atp11a,Sell,Lyn,Slc7a8,Abcc5,Parp11,Sdc1,Rab32,Ptch1,Htr2b,Slc39a4,Pdzd11,Rims3,Stoml1,Slc39a13,Rab9,Whamm,Slc43a3,Cox18,Atm,Acsl1,Rnf19b,Ccl9,Htr2a,Vps54,Myc,Myo10,Dcp1a,Spry2,Dock4,Slc48a1,Dennd1b,Csf3r,Ccrl2,Calhm6,Ezr,Dio2,Scyl2,Ddit4,Sdc2,Pf4,Fcgr1,Slc9a1,Gbp2,Ppfia3,Cxcl1,Ccl7,Ap3b1,Rhou,Phactr4,Tulp3,Mecp2,Ranbp2,Pou2f2,Abcc4,Optn,Apba1,Cxcl3,Adar,Mpp7,Crkl,Rin2,Slco3a1,Nlrc4,Flrt3,Lcn2,Kcnj2,4932438A13Rik,Sec24a,Sema3c,Hck,Stat3,Src,Egr3,Lpar1,Piezo1,Arl4a,Pdgfb,Dst,Ero1l,Ptafr,Cxcl10,Mark2,Txn1,Il1rn,Bcl6,Plod3,Ppp1r15a,Slc4a7,Tor1aip2,Notch2,Calcrl,Rab10,Fut8,Vcam1,Cxcl14,Fcgr2b,Ift57,Myd88,Serp1,Met,Rtn2,Magohb,Kitl,Cacna1d,Cx3cl1,Atp6v1d,Kdr,Egr2,Mppe1,Mapkapk2,Mdm2,Slc7a2,Palld,Clcn5,Nr4a3,Psmd10,Ccnd1,Hk2,Asap3,Ikbkg,Rhof,Itgav,Gja1,Rtp4,Sema4a,Rrbp1,Gem,Grk3,Cd34,Cacnb3,Thbs1,Trem1,Atp11b,Il6,Ap3m2,Hif1a |
| 2.067e-11 | -24.60 | GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 176 | 43 | 15632 | 1249 |
Dgka,Stat4,G3bp2,Nfkbib,Arl5b,Plekha2,Atp6v1d,Rel,Gna15,Tnfrsf1b,Ptges,Snn,Zhx2,Cldnd1,Chd9,Cxcl1,Gtpbp2,Ier3,Mafg,Grina,Slc43a3,Zc3h12a,Fndc3a,Ell2,Slc31a1,B3gnt5,Ccng2,Gadd45g,Kdm5b,Nfkbie,Mllt6,Serp1,Ddhd1,Nr4a1,Gadd45b,Plagl2,Tnfaip3,Olr1,Chmp4b,Sav1,Icam1,Lif,Malt1 |
| 2.105e-11 | -24.58 | IL-17 signaling pathway | KEGG pathways | mmu04657 | 91 | 31 | 7931 | 713 |
Tnf,Cxcl10,Ptgs2,Mmp9,Nfkbia,Fosb,Cxcl2,S100a8,Casp8,Lcn2,Traf5,Ikbke,Traf2,Cxcl1,Cxcl3,Ccl7,Jun,Nfkb1,Tab2,Il1b,Il6,Ikbkg,Ccl12,Usp25,Fos,Ccl2,Csf3,Tnfaip3,Casp3,Traf3ip2,Mmp13 |
| 2.105e-11 | -24.58 | IL-17 signaling pathway | KEGG pathways | ko04657 | 91 | 31 | 7931 | 713 |
Casp3,Tnfaip3,Ccl2,Csf3,Fos,Mmp13,Traf3ip2,Ikbkg,Il6,Il1b,Tab2,Usp25,Ccl12,Cxcl3,Ccl7,Cxcl1,Nfkb1,Jun,Nfkbia,Mmp9,Ptgs2,Tnf,Cxcl10,Traf2,Ikbke,Traf5,Casp8,Lcn2,S100a8,Cxcl2,Fosb |
| 2.199e-11 | -24.54 | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_UP | 190 | 45 | 15632 | 1249 |
Gpr35,Ctsc,Rin2,Rnf114,Crbn,Spsb1,Morc3,Dnaja1,Tspo,Pnpt1,Tmem176b,Rars,Pttg1,Timeless,Tifa,Csf1,Il18rap,Tor3a,Ptch1,Rgs1,Tax1bp1,Notch2,Ddx4,Batf2,Gbp4,Gbp9,Rsad2,Plekhf2,Klf6,Gpsm2,Tpst1,P2ry12,Rgs14,Homer1,Nupr1,Mcm10,Icam1,Usp18,Uba7,Brwd3,Igsf9,Plk2,Gca,Gcnt2,Ttc39b |
| 2.199e-11 | -24.54 | GSE43957_UNTREATED_VS_NACL_TREATED_ANTI_CD3_CD28_STIM_CD4_TCELL_DN | MSigDB lists | GSE43957_UNTREATED_VS_NACL_TREATED_ANTI_CD3_CD28_STIM_CD4_TCELL_DN | 190 | 45 | 15632 | 1249 |
Nfil3,Dusp16,Kdr,Clic4,Dr1,Map3k8,Mthfd2,Irf1,Adora2b,Rcan1,C3,Rac3,Ptger4,Rnf19b,Kpna3,Hk2,Noc4l,Ddit4,Procr,Fabp7,Cep350,Irf8,Il10,Ahr,Fcgr1,Myd88,Gmppb,Sphk1,Il4ra,Icam1,Cdkn2d,Mcoln2,Hlx,Ch25h,Sele,Errfi1,Ccl2,Pdpn,Egr2,Dusp2,Tor1aip2,Cd40,Txnrd1,Bcl2l11,Gadd45b |
| 2.336e-11 | -24.48 | MAHADEVAN_RESPONSE_TO_MP470_UP | MSigDB lists | MAHADEVAN_RESPONSE_TO_MP470_UP | 15 | 12 | 15632 | 1249 |
Vcam1,Cxcl10,Oas1g,Rsad2,Xaf1,Oas2,Cxcl2,Oas1a,Asns,Ccl5,Sod2,Psat1 |
| 2.466e-11 | -24.43 | regulation of chemotaxis | biological process | GO:0050920 | 213 | 44 | 20694 | 1406 |
Sell,Lyn,Tnfsf14,Gpr18,Swap70,Lgals9,Notch1,Il1b,Pdgfb,Dusp1,Cxcl10,Lpar1,Mtus1,Sema3c,Thbs1,Sema4a,Fpr2,Ptprj,Sema4c,Edn1,Stap1,Cxcl14,Nod2,Pla2g7,Serpine1,Ccl5,Csf1,Ptpn2,Pdgfrb,Cd74,Agrn,Vegfc,Bst1,Kdr,Ccl4,Cmklr1,P2ry12,Zswim4,Cx3cl1,Slamf8,Met,Ccl2,Ccr1,Ccl12 |
| 2.530e-11 | -24.40 | positive regulation of response to cytokine stimulus | biological process | GO:0060760 | 50 | 20 | 20694 | 1406 |
Zbp1,Nlrc5,Ifih1,Traf2,Ripk2,Irf7,Parp9,Irgm2,Ddx58,Ikbke,Csf1,Tlr2,Cd300lf,Casp4,Irgm1,Casp1,Axl,Cd74,Parp14,Gfi1 |
| 2.571e-11 | -24.38 | GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN | MSigDB lists | GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN | 157 | 40 | 15632 | 1249 |
Clec4e,Fcgr1,Nfkbiz,Irs2,Il1a,F11r,Upp1,Pnp2,Gpr68,Triobp,Bcl2a1d,Kremen1,Casp1,Bcl2a1b,Crbn,Tpst1,Bcl6,Arhgef3,Serpinb2,Cxcl1,Bcl2a1a,Il1b,Dusp28,Gng12,Rcl1,Fmnl2,Plaur,C3,Cd55,Nsmaf,Ptgs2,Acvr1b,Htra1,Procr,Cxcl2,Met,Hk2,Card6,Rabgef1,Pid1 |
| 2.608e-11 | -24.37 | GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_UP | MSigDB lists | GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_UP | 184 | 44 | 15632 | 1249 |
Samhd1,Col4a2,Nek6,Parp9,Slfn8,Fos,Gpr18,Cnn2,Nlrc5,Gramd1a,Pmepa1,Cd82,Sema4a,Cacnb3,Irf1,Oasl1,C3,Xaf1,Psme2,Hdc,Nfkb1,Tnfrsf1b,Tor3a,Gda,Arg2,Gbp3,Ddx58,C1ra,Dhx58,Rsad2,Aebp2,Ccnd1,Cish,Cd40,Timp1,Swap70,Slfn9,Dusp5,Parp3,Tlr1,Lad1,Klf2,Ccl5,Plek |
| 2.608e-11 | -24.37 | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | MSigDB lists | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | 184 | 44 | 15632 | 1249 |
Peli1,Irgm2,Pde5a,Cnn2,Gpr18,Gclc,Lpcat2,Ppm1l,Eef1e1,Tnfsf14,Gna15,Fscn1,Hsd17b7,Ap3m2,Stard7,Socs3,Adrb2,Ms4a6d,Rab21,D1Ertd622e,Glipr2,Arhgap26,Dpy19l1,Psmb9,Ube2f,Crlf3,Nod1,Myo10,Rhoc,Crim1,Cd38,Psme1,Prdm1,H2-Aa,Snx10,Fzd5,Daam1,Ppm1k,Cnp,Epsti1,Ripk2,Nsmaf,Tapbpl,4930453N24Rik |
| 2.608e-11 | -24.37 | GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | 184 | 44 | 15632 | 1249 |
Ccnd2,Tpx2,Atf3,Rbl1,Sgcb,Pnpt1,Zbp1,Gadd45b,Rnf114,Parp9,Samd9l,Ifnb1,Slfn8,Stap1,Tlr9,Etnk1,Ppa1,Jak2,Ccl4,Ubr4,Il10,Oas1a,Hivep3,Etv6,Rasgrp1,Akt3,Pigv,Isg15,Gbp3,1600014C10Rik,Cd40,Cish,Serpinb9,Dnaja2,Oas1g,Il15ra,Cmpk2,Zhx2,Slfn9,Igsf8,Snx2,Mmp13,Inpp5b,Slc2a6 |
| 2.708e-11 | -24.33 | regulation of T cell differentiation | biological process | GO:0045580 | 152 | 36 | 20694 | 1406 |
Ripk2,Hlx,Stat5a,Il2rg,Ap3b1,Socs1,Il6,Syk,H2-Aa,Rasgrp1,Tnfsf4,Il27,Prdm1,Tnfsf9,Egr3,Ikzf1,Irf1,Nfkbid,Ifnb1,Il4ra,Il15,Nfkbiz,Lgals9,Cd74,Zeb1,Pik3r6,Il1b,Nlrp3,Cd83,Bcl6,Ctla2a,Malt1,Ptpn2,Zc3h12a,Il18,Fgl2 |
| 2.743e-11 | -24.32 | tube morphogenesis | biological process | GO:0035239 | 710 | 97 | 20694 | 1406 |
Hmox1,Foxp4,Spint2,Notch1,Il18,Mthfd1l,Zc3h12a,Tiparp,Hlx,Flt1,Mthfr,Pdgfb,Spred1,Ldlr,Ptprj,Src,Bcl2l11,Egr3,Nr3c1,Csf1,Spry2,Col18a1,Sema4c,Edn1,Ccr3,Zeb1,Prkx,Kdm5b,Itgb8,Mmp14,Ptk2,Fzd5,Pdgfrb,Myc,Pdpn,Tnc,Vegfc,Phactr4,Ptger4,Tulp3,Acvr1,Nr4a1,Ccl2,Plau,Apaf1,Nr4a3,Ahr,Pbx1,Cav1,Casp3,Itgav,Lmo4,Cemip2,Gja1,Ptch1,Hhex,Hmga2,Pik3r6,Sirt1,Lox,Jag1,Ptgs2,Vasp,Hif1a,Bmp2,Sema4a,Lhx2,Timeless,Thbs1,Nrp2,Jmjd6,Notch2,Calcrl,Tmem67,Nox1,Wars,Clic4,Tnfaip2,Junb,Sec24b,Cx3cl1,Fzd1,Jun,Kdr,Cited2,Syk,Pde3b,Sdc4,Ccl12,Casp8,Pml,Met,Angpt1,Col4a2,Acvrl1,Prdm1,Ift57 |
| 2.747e-11 | -24.32 | MODULE_38 | MSigDB lists | MODULE_38 | 421 | 75 | 15632 | 1249 |
Upp1,Fgr,Plk3,Mthfr,Etv5,Crim1,Mvp,Tnfaip3,Cd14,Csf3r,Slc2a1,Tnf,Slc16a3,Ccnd1,Rbpms,Hspa2,Pnp2,Tgfbi,Pim1,Serpinb9,Hmox1,Dusp5,Glrx,Ppp1r15a,Lad1,Hopx,Serpine1,Fosb,Pdgfrb,Slc7a8,Junb,Gdf15,Psd4,Maff,Hap1,Dgka,Pdgfb,Scn1b,Etv3,Sdc1,Il4ra,Cdk5r1,Atf3,Plau,Cd34,Gng11,Zyx,Cited2,Ets2,Trip10,Flt1,Gadd45g,Dusp4,Ctsc,Fcgr2b,Pdpn,Ier3,Lyn,Itga5,Dnajb2,Cdkn1a,Hcls1,Adam19,Cav1,S100a8,Tnfrsf1b,Ikbkg,Ccne1,Ltbp2,Jag1,Smpdl3b,Pou2f2,Cnn3,Procr,Alas1 |
| 2.770e-11 | -24.31 | GNF2_INPP5D | MSigDB lists | GNF2_INPP5D | 63 | 24 | 15632 | 1249 |
Ifi204,Phf11d,Hcls1,Psd4,Psmb8,Mndal,Ifi208,Ifi211,Ifi203,H2-Q7,Psme1,Psmb10,Ifi214,Phf11a,Phf11c,Tap1,Ifi207,Phf11b,Ifi213,H2-Q4,Ifi205,Ifi209,H2-Q6,Tapbp |
| 2.905e-11 | -24.26 | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | MSigDB lists | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | 151 | 39 | 15632 | 1249 |
Ifi44,Stat3,Sat1,Gadd45g,Pcx,Errfi1,Sod2,Klf6,Nfkbia,Ifi213,Ifi209,Bcl6,Cited2,Ifi205,Tnfaip3,Gbp2,Mvp,Ifi207,Egr1,Nck1,Psme1,Atf3,Ifi214,F11r,Ifi208,Ifi211,Cxcl2,Ifi203,Birc3,S100a8,Mndal,Gem,Sema3c,Il1rn,Nfil3,Mmp25,Acsl1,Rnf145,Ifi204 |
| 2.947e-11 | -24.25 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_DN | 171 | 42 | 15632 | 1249 |
Atp10a,Endod1,Ebi3,Scyl2,Dck,Pim1,Rgs1,Ralgds,Sec24a,Prkx,Tagap,Agpat4,Slc4a7,Junb,Il10,Hopx,Plk2,Fosb,Btg2,Stat4,Sirt1,Rap1gap2,Leng9,Cd69,Adora2a,Il18rap,Plk3,Atf3,Itga4,Jmjd6,Slc16a1,Atp2b4,Olfml3,Tnfaip3,Dusp14,Dusp1,Nr4a1,Klf6,Cited2,Pnp2,Chst11,Hspa2 |
| 2.947e-11 | -24.25 | IL15_UP.V1_UP | MSigDB lists | IL15_UP.V1_UP | 171 | 42 | 15632 | 1249 |
Ahr,Rgs3,Slamf7,Bmp2,Socs1,Il1a,Egr1,Lrp8,Lif,Aim2,Acvrl1,Dusp4,Mafk,Egr2,Dusp2,Cish,Rab11fip1,Spry2,Kcnj2,Fos,Gadd45b,Ap3m2,Ccl4,Adam19,Trib1,Pim1,Pim2,Tlr3,Egr3,Il18rap,Hk2,Maff,Cd69,Kctd12,Slc7a5,Osm,Ptch1,Fzd5,Il10,Ccne1,Dusp6,Junb |
| 3.117e-11 | -24.19 | GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 931 | 132 | 15632 | 1249 |
Cd86,Plk2,Klf2,Ube2l6,Pdgfb,Nmi,Nfkbid,Uba7,Ptger4,Zc3h12a,Ptgs2,Cxcl10,Il12b,Cmklr1,Serpinb2,Thbs1,Plaur,Zhx2,Pf4,Axl,Lrp4,Timp1,Acvrl1,Hlx,Nfkbil1,Hhex,Lif,Pml,Calcrl,Ddx58,Hif1a,Isg15,Cd83,Bmp2,Notch1,Relb,Rabgef1,Il10,P2ry2,Ptch1,Procr,Jag1,Tnfsf4,Stat1,Irf1,Mefv,Sema4a,Adrb2,Gfi1,Cx3cr1,Nlrc5,Ezr,Nfkbia,Ccl12,Dock4,Edn1,Myc,Il6,Abr,Prnp,Il4ra,Nlrp3,Plau,Ciita,Pde3b,Atp2b4,Angpt1,H2-Eb1,Pde4b,Ccr1,Gja1,Cd274,Serpine1,Rapgef2,Inhba,Vasn,Tlr3,Hmox1,Adora2b,Ikbke,Plat,Il1b,Tnf,Bcl6,Stat3,Rab11fip1,Mecp2,Errfi1,Dhx58,Gpr68,Cd74,Tulp3,Ifih1,Rnf135,Sav1,Pbx1,Cd38,Irak3,Tnfaip3,Nfkb1,Ednrb,Cav1,Sema3c,Rel,Tmem176a,Rap1gap2,Sema4c,Tlr9,Ptk2,Lpar1,Trib1,Lyn,Jak2,Tax1bp1,Plac8,Ptpn2,Katna1,Stap1,Ifrd1,Ifnb1,Pde5a,Tmem176b,Evl,Bcor,Ubash3b,Nr1h3,Cx3cl1,Mul1,Cdk5r1,Col4a2,Cd34,Tspo |
| 3.163e-11 | -24.18 | GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_DN | MSigDB lists | GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_DN | 185 | 44 | 15632 | 1249 |
Zbp1,Pnpt1,Rnd3,Ahr,Nr1h3,Fpr2,Etv3,Trim13,Dusp4,Sod2,Ptpn2,Mrpl52,Chd9,Ccl4,Ldlr,Plekhn1,Stat1,Ptk2,Pstpip2,Adap2,Gbp7,Sgk3,Ddx58,Calcrl,Rab11fip1,Gsr,Mafk,Txnrd1,Ehd1,Oas3,Arid5a,Vcam1,Glrx,Zc3h12a,Map3k8,Ext1,Btg2,Parp12,Gja1,Junb,Jarid2,Slc4a7,Tor1aip1,Plk2 |
| 3.163e-11 | -24.18 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_UP | 185 | 44 | 15632 | 1249 |
Errfi1,Txnrd1,Myd88,Batf,Ch25h,Slc30a4,Mcoln2,Rhoh,Nupr1,Socs1,Gbp3,Ddit4,Reps1,Gja1,Lcp2,Col11a2,Igsf8,Ptger4,Ptgs2,Rcan1,Cxcl10,Map3k8,Fcgr2b,Dtnb,Gadd45b,Srm,Ccl12,Tiparp,Cdkn2d,Il4ra,Procr,Plscr1,Stat4,Met,Ptch1,Casp4,Gbp7,Rbms1,Jak2,Ccl4,Nfil3,Il13ra1,Socs3,Irf1 |
| 3.186e-11 | -24.17 | FRIDMAN_IMMORTALIZATION_DN | MSigDB lists | FRIDMAN_IMMORTALIZATION_DN | 40 | 19 | 15632 | 1249 |
Ifi213,Ifi205,Irf7,Ifi209,Mndal,Serpine1,Htra1,Ifi208,Ifi211,Hspa2,Ifi203,Cxcl14,Optn,Filip1l,Ifi214,Ifi204,Cdkn1a,Ahr,Ifi207 |
| 3.220e-11 | -24.16 | LEE_RECENT_THYMIC_EMIGRANT | MSigDB lists | LEE_RECENT_THYMIC_EMIGRANT | 199 | 46 | 15632 | 1249 |
Taf4b,Spry2,Jun,Plac8,Ifi207,Ubash3b,Pgm1,Mpp7,Ifi214,Nfkbiz,Bcor,Ccrl2,Rhou,Eef1e1,Ifi203,Ifi211,Plscr1,Vezt,Mndal,Pmepa1,Rgs1,Ifi204,Socs3,Tmod3,Aebp2,Lztfl1,Rsad2,Ccng2,Fut8,Egr2,Ifi209,Tcf4,Ifi205,Ifi213,Slc25a37,Tnfaip3,Gnb4,Atp11a,Isg15,Ifi208,Mthfd1l,Cmpk2,Htr2b,Tnfsf10,Ptger4,Pcgf5 |
| 3.245e-11 | -24.15 | response to interleukin-1 | biological process | GO:0070555 | 91 | 27 | 20694 | 1406 |
Src,Ccl2,Irf1,Tank,Myd88,Ccl12,Ccl4,Il6,Ccl3,Il1a,Ccl7,Saa3,Cx3cl1,Ripk2,Zc3h12a,Ccl22,Irak3,Ccl8,Irak2,Ccl9,Il1b,Sele,Acod1,Egr1,Ccl5,Nfkb1,Serpine1 |
| 3.337e-11 | -24.12 | DANG_REGULATED_BY_MYC_DN | MSigDB lists | DANG_REGULATED_BY_MYC_DN | 235 | 51 | 15632 | 1249 |
Rsad2,Ccng2,Mdm2,Errfi1,Ccnd1,Casp3,Phldb1,Casp1,Dusp1,Gbp2,Fzd1,Inhba,Pdlim7,Rab10,Pdgfb,Serpine1,Pdgfrb,Irf7,Ppp1r15a,Myo1b,Dusp6,Brd2,Ifit1bl2,Plaur,Thbs1,Vcam1,Cxcl10,Lox,Pim1,Hmox1,Oas1g,Gadd45g,Cpd,Myc,Edn1,Ifit1bl1,Plac8,Hivep2,Klf7,Gpc1,Tspo,Fas,Oas1a,Cav1,Itgal,Cdkn1a,H3f3b,Arf4,Acsl1,Ier3,Ifi35 |
| 3.338e-11 | -24.12 | PUJANA_ATM_PCC_NETWORK | MSigDB lists | PUJANA_ATM_PCC_NETWORK | 1291 | 169 | 15632 | 1249 |
Ifi44,Hdac1,Rsad2,Dock10,Ccng2,Tnf,Stat5a,Ifi209,Bcl6,Cd38,Plagl2,Aim2,Rnf139,Tulp3,Atp11a,Sap30,Nrp2,Icosl,Stxbp3,Eya4,Inhba,Snx2,Plek,Psd4,Rrs1,Ikbke,Nfkb2,Pgk1,Sp110,Parp3,Il2rg,Mcm6,Fcgr2b,Nat2,Katna1,Ap3b1,Psip1,Rnf114,Syk,Gpr18,Ptpn2,Trp53i11,Il15,Ifi207,Atp11b,Prpf4,Zc3hav1,Me1,Fas,Nck1,Dcp2,Ciapin1,Ifi214,Ifi211,Psme2,Pou2f2,Etv6,Atm,Nfkb1,Ikbkg,Rel,Mndal,Nos2,Casp8,Jak2,Clcn7,Ppp2r1b,Adam19,Abcc1,Wdr43,Mtdh,Max,Pim2,Ifi204,Odc1,Dnajb4,Lyn,Ifit3b,Mthfd2,Nr3c1,Casp3,Fchsd2,Ly75,Mdm2,Gsr,Ifi213,Sp140,Ppp6r1,Cd40,Tank,Slc2a1,Rbbp8,Ifi205,Crlf3,Ahsa1,Smg7,Itga4,Ube2e1,Psme1,Irf2,Lif,Rhoh,Apba1,Kdm4a,Ifi208,Nmi,Csf3,Hk2,Oas2,Jarid2,Gch1,Fubp1,Osbpl3,Plcl2,Dek,Tcea1,Zhx2,Tfec,Smc5,Ldha,Oas1g,Nsmaf,Ikzf1,Irf4,Myc,Taf4b,Tra2a,Flt1,Bcl2l11,Slc7a11,Ciita,Pfkfb3,Rbms2,Adar,Htr2a,Tap1,Tlr6,Phip,Nlrp3,Ampd3,Ep400,Timeless,Oas1a,Eef1e1,Hat1,Casp2,Rasgrp1,Ifi203,Psmb8,Ccne1,Itgal,Ifit3,Irf8,Dr1,Actb,Cflar,Tmem123,Hcls1,Asf1a,Stard7,Casp7,Dck,Stat1,Il13ra1,Itpkc,Dyrk2,Acvr1b,Gpd2,Pik3cd |
| 3.348e-11 | -24.12 | GO_LYMPHOCYTE_ACTIVATION | MSigDB lists | GO_LYMPHOCYTE_ACTIVATION | 326 | 63 | 15632 | 1249 |
Rhoh,Malt1,Hhex,Itga4,Jmjd6,Psmb10,Cd180,Icam1,Cd74,Batf,Relb,Ifna2,Ripk3,Ifnar1,Axl,Klf6,Bcl6,Cd40,Swap70,Tnfsf8,Rsad2,Treml2,Ripk2,Ptger4,Il12b,Clec4d,Il18,Plcl2,Vcam1,Cd86,Fzd5,Ifna6,Icosl,Egr1,Nck1,Fas,Slamf7,Cd80,Clec4e,Il15,Ifna1,Syk,Spn,Ptpn2,Il6,Irf4,Ikzf1,Ifnb1,Ifna5,Tnfsf4,Ebi3,Sema4a,Azi2,Pik3cd,Irf1,Clcf1,Notch2,Atm,Casp8,Itgal,Il10,Tnfsf14,Pou2f2 |
| 3.537e-11 | -24.07 | SEMENZA_HIF1_TARGETS | MSigDB lists | SEMENZA_HIF1_TARGETS | 36 | 18 | 15632 | 1249 |
P4ha2,Flt1,Hk1,Nos2,Serpine1,Eno1,Slc2a1,Cited2,Bnip3,Edn1,Cp,Hk2,Tpi1,Hmox1,Ldha,Pfkl,Pgk1,Cdkn1a |
| 3.537e-11 | -24.07 | GEISS_RESPONSE_TO_DSRNA_UP | MSigDB lists | GEISS_RESPONSE_TO_DSRNA_UP | 36 | 18 | 15632 | 1249 |
Tap1,Tnfaip3,Plaur,Tnfaip2,Ccl4,Adar,Cflar,Traf1,Irf1,Atf3,Nmi,Sat1,Bnip3,Birc2,Gch1,Nfkbia,Ifit1bl2,Ifit1bl1 |
| 3.604e-11 | -24.05 | GSE3982_NEUTROPHIL_VS_NKCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_NKCELL_UP | 172 | 42 | 15632 | 1249 |
Hlx,Mxd1,Slco3a1,Arl4a,Nlrp3,Tab2,Ddx58,Fpr2,Atp11a,Sla,Fcgr1,Cdc42ep2,Pfkfb3,Vcpip1,Gbp2,Klf7,Ifit2,Cd302,Acpp,Rnf24,Peli1,Ogfrl1,Mmp9,Stat1,Xkr8,Acsl1,Map2k4,Lyn,Rab20,Il1rn,Cflar,Glrx,Slc31a2,Ccr1,Mfap3l,Klf2,Rel,Ampd3,Plscr1,Slpi,Ext1,Tyk2 |
| 3.629e-11 | -24.04 | cellular response to chemokine | biological process | GO:1990869 | 79 | 25 | 20694 | 1406 |
Ccr1,Ccl12,Pf4,Gpr35,Ccl2,Lrch1,Cxcl1,Cx3cl1,Ccl3,Lox,Ccl7,Cxcl9,Cxcl10,Ccl4,Dusp1,Ccl9,Ccr3,Ccl8,Ccl22,Zc3h12a,Cxcl3,Cxcl2,Ccl5,Cxcl11,Ccrl2 |
| 3.629e-11 | -24.04 | response to chemokine | biological process | GO:1990868 | 79 | 25 | 20694 | 1406 |
Cxcl10,Ccl4,Ccrl2,Dusp1,Cxcl9,Cxcl11,Cx3cl1,Ccl5,Cxcl2,Lox,Ccl7,Ccl3,Lrch1,Cxcl1,Cxcl3,Zc3h12a,Gpr35,Ccl2,Ccl8,Pf4,Ccl22,Ccl9,Ccl12,Ccr3,Ccr1 |
| 3.641e-11 | -24.04 | positive regulation of nucleobase-containing compound metabolic process | biological process | GO:0045935 | 1862 | 199 | 20694 | 1406 |
Irf4,Zfp36,Dtx3l,Med13,Hivep3,Edn1,Nsd3,Nod2,Hmga1,Irf1,Hdac1,Nr4a1,Hinfp,Irf2,Acvr1,Tnfsf4,Il10,Ets2,Mov10,Zc3h12a,Il18,Notch1,Pid1,Gfi1,Pim1,Tlr2,Hivep2,Csf3,Tnfsf8,Rnf14,Nos2,Parp9,Junb,Max,Arid5b,Parp3,Pou3f1,Cd74,Phip,Dr1,Mtdh,Mycl,Igf1r,Psip1,Cd40,Kat2b,Jmjd6,Ifnb1,Ikzf1,Eya4,Pim2,Taf4b,Sertad3,Atf3,Pml,Bambi,Stat4,Cited2,Tnf,Daxx,Il1a,Ccl3,Tcf4,Pcgf5,Jun,Fzd1,Sirt1,Arf4,Hhex,Irf8,Ptch1,Lmo4,Helz2,Ahr,Pbx1,Clcf1,Spire1,Klf7,Tnip1,Ncoa7,Osm,Plscr1,Cd38,Timeless,Hsph1,Rap2c,Adora2b,Casz1,Atm,Nfil3,Klf6,Ahrr,Bcl9,Fos,Ier2,Dcp1a,Pdgfrb,Plagl2,Cebpd,Fzd5,Myc,Htr2a,Etv6,Fosb,Zeb1,Nr1h3,Csrnp1,Rhoq,Birc2,Spen,Ifrd1,Klf2,Nupr1,Aff1,Spic,Batf,Slc9a1,Med21,Pf4,Adrb2,Tlr9,Nfkbia,Maml2,Mllt6,Plekhn1,Rbpms,Cenpj,Arid4a,Mecp2,Ell2,Pnpt1,Plagl1,Stat5a,Tnfrsf1b,Plac8,Pou2f2,Nlrp3,Zc3hav1,Stat1,Jak2,Tcea1,Ddx58,Maff,Hmgn3,Inhba,Irf7,Egr3,Stat3,Src,Nr3c1,Hcls1,Map2k1,Tfec,Stat2,Mafg,Lif,Pdgfb,Wdr43,Ppp1r15a,Tra2a,Agrn,Kdm6b,Egr1,Rgcc,Acvrl1,Met,Nck1,Zfp281,Arid5a,Etv5,Nampt,Egr2,Nlrc5,Cx3cl1,Mdfic,Btg2,Il1b,Hmga2,Polr2g,Tet2,Fubp1,Ifnar1,Ikbkg,Tlr3,Nr4a3,Crlf3,Relb,Nfkb1,Fbxo4,Lhx2,Prdm9,Bmp2,Rel,Hif1a,Acvr1b,Il6,Nfkb2,Jag1,Ciita |
| 3.769e-11 | -24.00 | positive regulation of transcription by RNA polymerase II | biological process | GO:0045944 | 1246 | 146 | 20694 | 1406 |
Rhoq,Csrnp1,Edn1,Klf2,Ifrd1,Nod2,Hmga1,Irf4,Fzd5,Plagl2,Cebpd,Myc,Med13,Nr1h3,Etv6,Zeb1,Fosb,Arid4a,Ets2,Plagl1,Ell2,Stat5a,Irf1,Batf,Spic,Tlr9,Pf4,Adrb2,Nfkbia,Med21,Hdac1,Slc9a1,Irf2,Acvr1,Nr4a1,Mllt6,Il10,Maml2,Jak2,Stat1,Tcea1,Tlr2,Hmgn3,Ddx58,Maff,Irf7,Inhba,Il18,Zc3h12a,Pou2f2,Plac8,Nlrp3,Notch1,Gfi1,Pid1,Mafg,Pdgfb,Lif,Csf3,Stat3,Hivep2,Egr3,Nr3c1,Tnfsf8,Map2k1,Hcls1,Stat2,Tfec,Dr1,Phip,Cd40,Psip1,Mycl,Rgcc,Egr1,Ifnb1,Kat2b,Jmjd6,Junb,Max,Kdm6b,Agrn,Pou3f1,Egr2,Cited2,Nlrc5,Stat4,Daxx,Ccl3,Il1a,Tnf,Cx3cl1,Pcgf5,Jun,Tcf4,Met,Ikzf1,Acvrl1,Zfp281,Nck1,Taf4b,Etv5,Arid5a,Nampt,Pml,Atf3,Ikbkg,Lmo4,Tlr3,Helz2,Nr4a3,Ahr,Pbx1,Osm,Nfkb1,Relb,Ncoa7,Tnip1,Crlf3,Klf7,Sirt1,Arf4,Hhex,Hmga2,Il1b,Irf8,Fubp1,Tet2,Hif1a,Acvr1b,Klf6,Nfkb2,Atm,Il6,Jag1,Ahrr,Ier2,Fos,Bcl9,Ciita,Plscr1,Prdm9,Lhx2,Hsph1,Bmp2,Rel |
| 3.771e-11 | -24.00 | MODULE_18 | MSigDB lists | MODULE_18 | 432 | 76 | 15632 | 1249 |
Rac3,Ier3,Ifi204,Ikbkg,Plod2,Mndal,Cav1,Sema3c,Plscr1,St3gal5,Nfkbib,Trip13,Cnn3,Fabp7,Ifi211,Procr,Eef1e1,Hat1,Casp2,Ifi203,Smpdl3b,Ifi214,Tpx2,Gbe1,Cdk5r1,Sdc1,Pttg1,Ciapin1,Gng11,Htr2a,Rnd3,Angpt1,Ifi207,Slc7a11,Ifit1bl1,Tspan3,Myc,Ctsc,Gclm,Nqo1,Dusp4,Ap3b1,Mcm6,Rcan1,Plat,Bambi,Gng12,Gdf15,Dusp6,Cdyl,Ifit1bl2,Jarid2,Serpine1,Plk2,Asns,Cnp,Tor1aip1,Ifi208,Slc7a5,Ddit4,Hap1,Myo10,Etv5,Crim1,Slc16a3,Apobec3,Cst7,Tnf,Ifi213,Ifi209,Slc2a1,Ifi205,Rbbp8,Mtus1,D1Ertd622e,Tnc |
| 3.870e-11 | -23.98 | GO_CYTOKINE_ACTIVITY | MSigDB lists | GO_CYTOKINE_ACTIVITY | 193 | 45 | 15632 | 1249 |
Ccl12,Il6,Ccl2,Edn1,Ifna5,Ifnb1,Cxcl14,Cx3cl1,Ccl22,Il15,Il27,Ifna1,Il10,Tnfsf14,Csf1,Tnfsf4,Ebi3,Ccl4,Clcf1,Tnf,Timp1,Tnfsf8,Lif,Il1a,Bmp2,Ccl3,Ifna2,Ccl5,Gdf15,Nampt,Osm,Tnfsf15,Ifna6,Cxcl2,Inhba,Csf3,Cxcl10,Il12b,Il18,Tnfsf10,Kitl,Cxcl1,Il1rn,Il1b,Pf4 |
| 3.917e-11 | -23.96 | MODULE_119 | MSigDB lists | MODULE_119 | 133 | 36 | 15632 | 1249 |
H2-Q7,Sell,Xrn1,Pttg1,Cd74,Stat2,Pnpt1,Il15,Samhd1,Hvcn1,Casp1,Armcx6,H2-Q4,Nlrc5,H2-Q6,Irf4,Abcb1a,Pim2,Cd200,Mthfd2,Kcna3,Irf1,Tnfaip2,Vcam1,Plcl2,Acp2,Sp110,Rnf31,Irf7,Samsn1,Isg20,Syne2,Spint2,Dgka,Pou2f2,Stat4 |
| 4.060e-11 | -23.93 | GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_UP | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_UP | 146 | 38 | 15632 | 1249 |
Parp9,Dhx58,Sat1,Parp14,Il4i1,Ly75,Oas3,Dnaja1,Ifnar1,Slamf7,Adar,Stat2,Cyth3,Dmxl2,Ifih1,Dtx3l,Nupr1,Tdrd7,Nrp2,Akt3,Psme2,Sema3c,Irf7,Tor3a,Abtb2,Epsti1,Htr2b,Trafd1,Rgs1,Tnfaip2,Pim1,Il12b,Sema4a,Cdc42ep4,Ebi3,Pcgf5,Stat1,Mmp9 |
| 4.130e-11 | -23.91 | GO_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | 91 | 29 | 15632 | 1249 |
Tnf,Axl,H2-Q4,Ifnar1,H2-Q6,Il27,Cd14,Ripk3,H2-Q7,Prnp,Isg15,Il12rb1,Inhba,Rasgrp1,Pde4b,H2-Eb1,Fzd5,Cd274,Irf8,Il10,Il1b,Tlr9,Tnfsf4,Tlr3,Ebi3,Zc3h12a,Ripk2,Il18,Il12b |
| 4.399e-11 | -23.85 | GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP | 173 | 42 | 15632 | 1249 |
Ppm1k,Sco1,Lgals9,Slfn4,Igsf8,Inhba,Stx11,Oas2,Isg20,Slc9a1,Timeless,Ms4a6d,Slc25a22,Sema4c,Casp7,Epsti1,Tmem219,Ap3m2,Trafd1,Slfn3,Gtpbp2,Ccl4,Tnip1,Psmb9,Oas3,Nlrc5,Plac8,Hdac1,Cdyl2,Stk40,Pla2g4a,Stat2,Spata13,Coa5,Sertad3,Pml,Enpp4,Rhoc,Mapkbp1,Zbp1,Pde3b,Lpcat2 |
| 4.427e-11 | -23.84 | GO_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 45 | 20 | 15632 | 1249 |
Irak3,Tnfaip3,Gfi1,Cd14,Lyn,Nr1h3,Tlr2,Irf1,Tlr3,Tlr9,Nfkbil1,Rsad2,Smpdl3b,Peli1,Wdfy1,Irf4,Birc2,Irf7,Cav1,Birc3 |
| 4.544e-11 | -23.81 | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_DN | 180 | 43 | 15632 | 1249 |
P2ry13,Timp1,Dse,Plod3,Parp8,Cebpd,Slc15a3,Ifi44,Cd74,Ch25h,Hck,Atp6v1d,Rnaset2a,Cd86,Plek,Tlr1,Il18,Fndc3a,H2-Ab1,Tfec,Gca,Cmklr1,Ccl12,Syk,Sdc2,Rin2,Ctsc,Nr1h3,Tmem176b,Slamf7,Il10,Tmem176a,Kctd12,Tdrd7,Jag1,Pla2g7,Mmd,St3gal5,Sema4a,Cdkn1a,Agpat4,Rnaset2b,Ust |
| 4.629e-11 | -23.80 | GSE10325_BCELL_VS_MYELOID_DN | MSigDB lists | GSE10325_BCELL_VS_MYELOID_DN | 187 | 44 | 15632 | 1249 |
Icam1,Myd88,Tnfrsf8,Dusp1,Casp1,P2ry13,Cd302,Sat1,Fgl2,Cebpd,Hmox1,Adora2b,Slc43a3,Tgfbi,Fpr1,Il1rn,Cmklr1,Plaur,Ccr1,Slc31a2,Dusp6,Nlrp3,Pilra,Hk3,Rab32,Aoah,Dhrs9,Cyfip1,Fos,Igsf6,Rin2,Nod2,Cpd,Dram1,Ptgir,Oasl1,Ms4a6d,Tlr2,Tnfaip2,Pdk3,Tnfrsf1b,Gna15,Htra1,Kctd12 |
| 4.629e-11 | -23.80 | GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_UP | MSigDB lists | GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_UP | 187 | 44 | 15632 | 1249 |
Pim3,Crlf3,Cd80,Enpp4,Ifit1,Tnfaip3,Prdm1,Plk3,Egr1,Csrnp1,Hif1a,Il1a,Jmjd6,Rnd1,Gpr84,Il6,Dusp2,Errfi1,Tnf,Nfkbia,P2ry13,Jun,Slfn3,Rsbn1,Dek,Irak2,Ralgds,Serpinb2,Rnaset2b,Il1b,Tfec,Itpkc,Chic2,Tlr1,Stxbp3,Ccrl2,Cd69,Pde4b,Plk2,Samsn1,Rnaset2a,Slfn4,Osm,Gem |
| 4.629e-11 | -23.80 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_UP | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_UP | 187 | 44 | 15632 | 1249 |
P2ry14,Papss2,Ifi214,Aff1,Ifi207,Srm,Dhrs9,Il18bp,Mllt6,Myc,Ccl2,Fcgr2b,Rcsd1,Ifi204,Mob3c,Tnfaip2,Tnip1,Lrrc25,Mndal,Atm,Birc3,Ifi203,St3gal5,Ifi211,Slco3a1,Hlx,Ifi205,Tcf4,P2ry13,Ifi209,P2ry12,Ifi213,Ehd1,Mcm6,Il2rg,Cxcl1,Pik3r6,Nampt,Plek,Oas2,Slc25a12,Ifi208,Nrp2,Ext1 |
| 4.658e-11 | -23.79 | GSE360_CTRL_VS_L_MAJOR_DC_DN | MSigDB lists | GSE360_CTRL_VS_L_MAJOR_DC_DN | 194 | 45 | 15632 | 1249 |
Fcgr2b,Ets2,Itgav,Sod2,Ccl12,Ahr,Tap1,Arl4a,Irs2,Pou2f2,Tdrd7,Psme2,Slpi,Il10,Eno2,Adam19,Rgs1,Cflar,Ier3,Irf1,Trib1,Mmp9,Ell2,Ifi35,Rhoq,Cd40,Timp1,Psmb9,Tnf,Klf6,Tnfaip3,Batf,Marcksl1,Psme1,Ddit4,Ube2l6,Rgl1,Nampt,Zhx2,Il1rn,Serpinb9,Pim1,Dusp5,Rnf19b,Kdm6b |
| 4.663e-11 | -23.79 | membrane raft | cellular component | GO:0045121 | 364 | 61 | 20747 | 1409 |
Cd14,Prkar2b,Tlr2,Kdr,Hspa1a,Src,P2ry12,Angpt1,Lcp2,Prnp,Ezr,Birc2,Cav1,Myadm,Igf1r,Eno1,Slc9a1,Ptgs2,Fcgr1,Jak2,Birc3,Slc2a1,Tnfrsf1b,Eno2,Hk1,Pdpn,Itpr1,Icam1,Fas,Ednrb,Lrp8,Sele,Adrb2,Lipe,Asah2,Gja1,Pikfyve,Casp3,Tnf,Fcgr2b,Grk3,Tlr6,Plscr1,Lyn,Sdc4,Traf2,Ptch1,Casp8,Lrp4,Actb,Tlr1,Ldlr,Kcna3,Gpc1,Hck,Pgk1,Cd55,Ppp2r1b,Hmox1,Rhoq,Cflar |
| 5.077e-11 | -23.70 | circulatory system development | biological process | GO:0072359 | 919 | 116 | 20694 | 1406 |
Prokr1,Notch1,Sgcb,Tiparp,Il18,Tnfrsf1b,Zc3h12a,Hmox1,Crkl,Sphk1,Errfi1,Foxp4,Flrt3,Bcor,Map2k1,Ldlr,Ptprj,Sema3c,Egr3,Tab2,Pdgfb,Lif,Spred1,Vcan,Flt1,Ptk2,Ccr3,Casp7,Prkx,Itgb8,Sav1,Itga4,Fzd5,Pdgfrb,Flrt2,Col18a1,Adap2,Antxr1,Edn1,Map2k4,Tnfsf4,Acvr1,Nr4a1,Slc9a1,Plau,Ccl2,Adgrg6,Adam19,Pdpn,Hopx,Vegfc,Ptger4,Plpp3,Socs3,Mmp13,Hhex,Pik3r6,Mdm2,Sirt1,Mmp9,Cav1,Ahr,Casp3,Lmo4,Cemip2,Itgav,Ptch1,Htr2b,Gja1,Dnaaf3,Sema4a,Bmp2,Rapgef2,Thbs1,Nrp2,Lox,Jag1,Ptgs2,Atm,Hif1a,Tnfaip2,Kdm6b,Sec24b,Rpgrip1l,Pdlim7,Junb,Slc4a7,Jmjd6,Calcrl,Notch2,Egr1,Ankrd17,Clic4,Vcam1,Tmem67,Wars,Nox1,Casp8,Cdkn1a,Ccl12,Gys1,Prdm1,Ift57,Met,Col4a2,Angpt1,Acvrl1,Fzd1,Sod2,Jun,Cx3cl1,Cacybp,Syk,Pde3b,Cited2,Kdr |
| 5.078e-11 | -23.70 | positive regulation of transcription, DNA-templated | biological process | GO:0045893 | 1550 | 172 | 20694 | 1406 |
Nr3c1,Egr3,Src,Stat3,Tfec,Stat2,Hcls1,Map2k1,Pdgfb,Lif,Mafg,Wdr43,Plac8,Pou2f2,Nlrp3,Tcea1,Jak2,Stat1,Irf7,Inhba,Ddx58,Maff,Hmgn3,Med21,Slc9a1,Tlr9,Adrb2,Nfkbia,Pf4,Spic,Batf,Maml2,Mllt6,Mecp2,Arid4a,Stat5a,Ell2,Plagl1,Myc,Fzd5,Dcp1a,Plagl2,Cebpd,Fosb,Etv6,Zeb1,Nr1h3,Spen,Klf2,Ifrd1,Csrnp1,Rhoq,Aff1,Lhx2,Prdm9,Rel,Bmp2,Il6,Nfkb2,Hif1a,Acvr1b,Ciita,Jag1,Fubp1,Tet2,Il1b,Hmga2,Tlr3,Ifnar1,Ikbkg,Crlf3,Nfkb1,Relb,Nr4a3,Zfp281,Nck1,Acvrl1,Met,Nampt,Etv5,Arid5a,Nlrc5,Egr2,Cx3cl1,Mdfic,Ppp1r15a,Kdm6b,Agrn,Egr1,Rgcc,Hivep2,Csf3,Tnfsf8,Parp9,Rnf14,Zc3h12a,Il18,Pid1,Gfi1,Notch1,Pim1,Tlr2,Hdac1,Irf1,Il10,Irf2,Acvr1,Hinfp,Nr4a1,Ets2,Dtx3l,Irf4,Med13,Hivep3,Edn1,Nod2,Hmga1,Nsd3,Hsph1,Cd38,Plscr1,Nfil3,Atm,Klf6,Casz1,Bcl9,Ier2,Fos,Ahrr,Arf4,Sirt1,Irf8,Hhex,Helz2,Lmo4,Ptch1,Klf7,Osm,Ncoa7,Tnip1,Pbx1,Ahr,Ikzf1,Atf3,Pml,Sertad3,Taf4b,Pim2,Stat4,Cited2,Bambi,Jun,Tcf4,Pcgf5,Fzd1,Tnf,Ccl3,Il1a,Daxx,Max,Junb,Cd74,Pou3f1,Mycl,Cd40,Psip1,Igf1r,Phip,Dr1,Ifnb1,Jmjd6,Kat2b |
| 5.120e-11 | -23.70 | CHYLA_CBFA2T3_TARGETS_UP | MSigDB lists | CHYLA_CBFA2T3_TARGETS_UP | 361 | 67 | 15632 | 1249 |
Nek6,P2ry14,Nr1h3,Cdk5r1,Ubash3b,Sgms2,Ccnd2,Clec4e,Cd34,F10,Olr1,Slc28a2,Hk3,Ass1,Cx3cr1,Gadd45b,Flt1,Tet2,Dusp2,Igsf6,Ctsc,Fcgr2b,Uaca,Ebi3,Dram1,Mefv,Chd9,Sh3bgrl2,Gfi1,Ppfibp2,Trem1,Plekha2,Hdc,Slpi,Alas1,Egln3,Hivep3,Csrnp1,Slco3a1,Gbp3,Klf8,Gys1,Hvcn1,Casp1,Cst7,Plod3,Parp8,Ttc39c,Arid5a,Mtus1,Arhgef3,Rhoq,C1ra,Cers6,Rbpms,Ptprj,Hp,Atp10a,Clec4d,Tgfbi,Clec5a,Ikbke,Serpinb2,Gca,Tfec,Ppm1k,H2-Aa |
| 5.130e-11 | -23.69 | GO_REGULATION_OF_PROTEIN_SECRETION | MSigDB lists | GO_REGULATION_OF_PROTEIN_SECRETION | 353 | 66 | 15632 | 1249 |
Slc16a1,Clec4e,Pim3,Cd34,Angpt1,Tnfrsf14,Tlr6,Nlrp3,Irs2,Cx3cl1,Il4ra,Nr1h3,Il6,Prkce,Nod2,Syk,Gsdmd,Ezr,Jak2,Cacna1d,Nlgn2,Pfkl,Tnfsf4,Tlr9,Lyn,Tlr2,Rasgrp1,Clec4n,Rabgef1,Nos2,Il10,Cd14,Cd38,Pml,Aim2,Fgr,Socs1,Hif1a,Il1a,Rab11fip1,Rsad2,Gpr68,Ifnar1,Casp1,Tnf,Src,Serp1,Cd40,Slc2a1,Rhbdf2,Traf2,Itpr1,Sec24a,Hcar2,Il1b,Htr2b,Vegfc,Zc3h12a,Ptger4,Clec5a,Tlr1,Mmp13,Gja1,Ccl5,H2-Eb1,Cd274 |
| 5.238e-11 | -23.67 | membrane microdomain | cellular component | GO:0098857 | 365 | 61 | 20747 | 1409 |
Tlr6,Plscr1,Lyn,Sdc4,Traf2,Ptch1,Actb,Casp8,Lrp4,Hck,Ldlr,Tlr1,Kcna3,Gpc1,Rhoq,Hmox1,Cflar,Pgk1,Ppp2r1b,Cd55,Sele,Lrp8,Adrb2,Lipe,Gja1,Asah2,Pikfyve,Casp3,Fcgr2b,Tnf,Grk3,Birc2,Cav1,Myadm,Ptgs2,Igf1r,Eno1,Slc9a1,Jak2,Birc3,Slc2a1,Fcgr1,Tnfrsf1b,Icam1,Pdpn,Hk1,Itpr1,Eno2,Ednrb,Fas,Cd14,Prkar2b,Kdr,Tlr2,Hspa1a,Src,P2ry12,Prnp,Lcp2,Angpt1,Ezr |
| 5.360e-11 | -23.65 | GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_UP | MSigDB lists | GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_UP | 174 | 42 | 15632 | 1249 |
Pml,Stat2,Socs1,Psmb10,Nr1h3,P2ry14,Fcgr1,Cd38,Gbp2,Tap1,Stat5a,Psmb9,Ptpn2,Mgat1,Ggct,Ctsc,Bbx,Ifi44,Fgl2,Cers6,Dtnb,Ifi35,Pim1,Irf1,Cxcl10,Tnfsf10,Tnfaip2,Prkx,Ppfibp2,Sp110,Trafd1,Slc31a2,Gch1,Tap2,Ube2l6,Alas1,St3gal5,Ccrl2,Wars,Oas2,Spint2,Xaf1 |
| 5.360e-11 | -23.65 | GSE36826_WT_VS_IL1R_KO_SKIN_DN | MSigDB lists | GSE36826_WT_VS_IL1R_KO_SKIN_DN | 174 | 42 | 15632 | 1249 |
Sgcb,Gclc,Gng11,Olr1,Lrp8,Traf1,Irf4,Pnp2,Aftph,Stard5,Vcan,Tra2a,Dusp1,Slc25a37,Spn,Cst7,Slc7a11,Ppp1r14b,Dse,Orai2,Actb,Thbs1,Hcls1,H3f3b,Trem1,Igf2bp2,Cdkn1a,Pf4,Ldha,Fpr1,Spen,Pdlim7,Dgka,Nampt,Eif4g2,Dusp6,Ikbkg,Rel,Pid1,Ppp1r15a,Gna15,Lad1 |
| 5.442e-11 | -23.63 | regulation of smooth muscle cell proliferation | biological process | GO:0048660 | 163 | 37 | 20694 | 1406 |
Cav1,Calcrl,Trib1,Tnfaip3,Ccl5,Egr1,Nr4a3,Hmox1,Il15,Igf1r,Nox1,Stat1,Jak2,Edn1,Ptk2,Il12b,Ptgir,Myc,Mdm2,Abcc4,Pdgfrb,Il18,Mmp9,Jun,Sod2,Ptgs2,Cx3cl1,Tnf,Il6,Pdgfb,Hif1a,Ptafr,Cdkn1a,Il10,Nampt,Thbs1,Myd88 |
| 5.457e-11 | -23.63 | LI_WILMS_TUMOR_ANAPLASTIC_DN | MSigDB lists | LI_WILMS_TUMOR_ANAPLASTIC_DN | 13 | 11 | 15632 | 1249 |
Ifi213,Ifi205,Ifi214,Mndal,Ifi209,Ifi204,Ifi208,Ifi211,Ifi203,Stat4,Ifi207 |
| 5.495e-11 | -23.62 | MCDOWELL_ACUTE_LUNG_INJURY_UP | MSigDB lists | MCDOWELL_ACUTE_LUNG_INJURY_UP | 41 | 19 | 15632 | 1249 |
Tgfbi,Sphk1,Il4ra,Lox,Ptges,Cdkn1a,Klf6,Dusp1,Nfkbia,Nr4a1,S100a8,Txnrd1,Fos,Lcn2,Btg2,Tnc,Myc,Zfp36,Pla2g7 |
| 5.509e-11 | -23.62 | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN | 181 | 43 | 15632 | 1249 |
Isg20,Zeb1,Zfp36,Junb,Hk1,Gja1,Irf8,P2ry2,Casp4,Ldlr,Tax1bp1,Ralgds,Trafd1,Ptger4,Azi2,Fcgr2b,Stat3,Abcb1a,Cp,Dusp2,Cebpd,Stat5a,Spsb1,Hivep2,Bcl2l11,N4bp1,Zyx,Bcl6,Tiparp,Batf,Myd88,Pfkfb3,Apaf1,Tle3,Ahr,Hck,Ier2,Psme1,Cdkn2d,Zfp281,Atp11a,Pgm1,Arg2 |
| 5.509e-11 | -23.62 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_DN | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_DN | 181 | 43 | 15632 | 1249 |
Hhex,Psme1,Tpi1,F11r,Ifi214,Rnf34,Myd88,Hinfp,Ifi207,Mvp,Tap1,Ifi213,Ifit2,Crbn,Psmb9,Ifi209,Ifi205,Tbc1d1,Dennd1b,Fgl2,Nod2,Triobp,Cebpd,Oas1g,Stat1,Hmox1,Il13ra1,Ifi204,Tgfbi,Cxcl10,Jak2,Tnfsf10,Vrk2,Fcgr4,Slc31a2,Cd86,Lap3,Mndal,Ifi211,Ifi208,Htra1,Oas1a,Ifi203 |
| 5.509e-11 | -23.62 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 181 | 43 | 15632 | 1249 |
Gclm,Ctsc,Nod2,Ogfrl1,Ifi213,Tnf,Ttc39c,Ifi205,Ifi209,Atp2b4,Rgs3,Ifi207,Mdfic,Ahr,Fas,Pttg1,Cd74,Ifi214,Ifi211,Sap30,Ifi208,Piezo1,Ifi203,Rhou,Stx11,Txn1,Tor3a,Ccl5,Hopx,Mndal,Osbpl3,Gbp2b,Adam19,Ust,Cldnd1,Il15ra,Pfkl,Dusp16,Lacc1,Tlr3,Dusp5,Ldha,Ifi204 |
| 5.509e-11 | -23.62 | GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_UP | MSigDB lists | GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_UP | 181 | 43 | 15632 | 1249 |
Mlkl,Tbc1d1,Sat1,Timp1,Zmynd15,Rhbdf2,Upp1,Gbp3,Fgr,Bst1,Pdgfb,Gpr132,Slc7a5,Ccl5,Trafd1,Il1b,Snn,Ikbke,Il18,Cd55,Ripk2,Hivep2,Ccl12,Olr1,Rnd3,Mmd,Ampd3,Psme2,C1rl,Tnfrsf1b,Agpat4,Ppfibp2,Cdkn1a,Cd300lf,Tnfaip2,Fam20c,Irf1,Rcn1,Acsl1,Rab20,Mtmr14,Endod1,C3 |
| 5.586e-11 | -23.61 | GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN | 188 | 44 | 15632 | 1249 |
Glrx,Gca,Fpr1,Ptafr,Rtn1,Ext1,Ccr1,Slc31a2,Snx10,Dusp6,Irak3,Cd14,Fgr,Arhgap26,Fgl2,Cebpd,Rhoq,Slc15a3,Bcl6,Mgat1,Csf3r,Casp1,Notch2,Siglece,Tnfaip2,Tlr2,Sema4a,Acsl1,Mtmr14,Kctd12,Plscr1,Adap2,Tnfrsf1b,Hk3,Pilra,Plagl1,Nlrp3,Dmxl2,Vcan,Rin2,Nod2,Igsf6,Rab32,Syk |
| 5.587e-11 | -23.61 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP | 70 | 25 | 15632 | 1249 |
Sqstm1,Slc7a11,Klf6,Dusp1,Tiparp,Jun,Myc,Gclm,Spry2,Ccng2,Acvr1,Egr1,Prnp,Cdc42ep2,Pim3,Slc25a25,Ahr,Gdf15,Slc4a7,Zfp36,Rictor,Spire1,Cldnd1,Cflar,Zcchc2 |
| 5.597e-11 | -23.61 | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN | 195 | 45 | 15632 | 1249 |
Trib1,Acsl1,Rab20,Sema4a,Siglece,Trem1,Nfil3,Tnfrsf1b,Gna15,Pid1,Atf3,Slc30a1,Nlrp3,Pilra,Aoah,Rab32,Cyfip1,Zyx,Cpd,Hmox1,Rtn1,Fpr1,Cdc42ep4,Il1rn,Plaur,Slc31a2,Ccr1,Nampt,Dusp6,Cd86,Ext1,Bst1,Stx11,Fzd1,Upp1,Icam1,St3gal6,Slco3a1,Cd14,Irak3,Csf3r,Eno1,Cd302,Ogfrl1,Cebpd |
| 5.597e-11 | -23.61 | negative regulation of protein kinase activity | biological process | GO:0006469 | 210 | 43 | 20694 | 1406 |
Trib3,Rgs14,Il1b,Spred3,Gadd45b,Hhex,Irak3,Gadd45g,Aida,Dusp4,Actb,Ptpn2,Sirt1,Uchl1,Spry2,Tnfaip3,Cav1,Trib1,Lyn,Kat2b,Cdkn2d,Adar,Prkar2b,Igf1r,Dnaja1,Wars,Casp3,Dusp16,Errfi1,Cdkn1a,Ptprj,Dusp2,Nck1,Fam72a,Dusp5,Dusp8,Mvp,Adora2a,Il6,Spred1,Ubash3b,Dusp6,Dusp1 |
| 5.668e-11 | -23.59 | granulocyte migration | biological process | GO:0097530 | 93 | 27 | 20694 | 1406 |
Pf4,Trem1,Ccl2,S100a8,Ccl12,Mcoln2,Cxcl9,Syk,Ccl4,Cxcl10,Cxcl1,Cx3cl1,Ccl7,Ccl3,Ccl8,Pde4b,Ccl22,Itga9,Ccl9,Il1b,Il1rn,Ccr3,Csf3r,Cxcl3,Cxcl2,Ccl5,Cxcl11 |
| 5.869e-11 | -23.56 | leukocyte mediated immunity | biological process | GO:0002443 | 171 | 38 | 20694 | 1406 |
C1rl,Serpinb9,Dennd1b,Nr4a3,Icam1,Fas,Irf7,Lyn,Nod2,Il4ra,Serpinb9b,Il12b,C1ra,Rnf19b,C3,Cd74,Cd55,Swap70,Fgl2,Il18,Pou2f2,Jag1,Raet1e,Ctsc,Rasgrp1,Il18rap,Stx11,Fcgr2b,H60b,H2-Ab1,Trem1,Batf,Myd88,Icosl,Fcgr1,Milr1,Treml4,Prdx1 |
| 6.005e-11 | -23.54 | enzyme regulator activity | molecular function | GO:0030234 | 958 | 121 | 20217 | 1400 |
Nck1,Hsph1,Rin2,Cdk5r1,Ppp1r12b,Parp9,Dtx3l,Rgs3,Rictor,Rcan1,Crim1,Ctla2b,Abr,Timp1,Ppp1r14b,Ripk3,Tank,Tor1aip2,Bcl2a1d,Cdkn1a,Tagap,Cdkn2d,Adap2,Ppp1r15b,Mmp25,Ppp2r1b,Dnajb2,Dock4,Wars,Ahsa1,Atp2b4,Irgm2,Mtcp1,Pik3r5,Elmod2,Ccnd1,Serpina3g,Trib1,Apaf1,Slpi,Sipa1l1,C3,Ccnj,Serpinb9b,Pik3r6,Tor1aip1,Dnajb4,Serpinb6b,Cav1,Prdx5,Cflar,Socs1,Bmp2,Prkce,Dnaja2,Htr2b,Gpsm2,Rgs1,Nsmaf,Malt1,Dnaja1,Socs7,Spry2,Lgals9,Ccl5,Wfdc17,Cd55,Kat2b,Nos2,Map2k1,Asap3,Ppp1r15a,Ppp2r2a,Notch1,Ccng2,Ccnd2,Rgs14,Casp3,Spred1,Jun,Agrn,Phactr4,Ppp2r5a,Ralgds,Ikbke,Tbc1d1,Ppp4r2,Rap1gap2,Rgcc,Arhgap26,Gclm,Dcp1a,Ctsc,Sh3bp4,Pdgfb,Tbc1d13,Prkar2b,Ppp2r3a,Ranbp2,Serpine1,Birc2,Birc3,Cst7,Serpina3f,Cish,Socs3,Serpinb2,Cdc42ep2,Daxx,Tnfsf14,Psme2,Spint2,Cox17,Rhoh,Psme1,Rapgef2,Pttg1,Serpinb9,Ccne1,Nupr1,Trib3 |
| 6.025e-11 | -23.53 | KEGG_APOPTOSIS | MSigDB lists | KEGG_APOPTOSIS | 81 | 27 | 15632 | 1249 |
Nfkbia,Tnf,Pik3r5,Traf2,Birc2,Cycs,Casp3,Fas,Il1a,Myd88,Apaf1,Irak3,Atm,Birc3,Ikbkg,Nfkb1,Casp8,Akt3,Endod1,Casp7,Pik3cd,Cflar,Tnfsf10,Prkx,Irak2,Il1b,Prkar2b |
| 6.025e-11 | -23.53 | FRIDMAN_SENESCENCE_UP | MSigDB lists | FRIDMAN_SENESCENCE_UP | 81 | 27 | 15632 | 1249 |
Ifi213,Ifi209,Ifi205,Cited2,Optn,Mdm2,Ccnd1,Cxcl14,Hspa2,Cdkn2d,Ifi214,Isg15,Ifi207,Tnfaip3,Mndal,Serpine1,Irf7,Ifi211,Ifi208,Ifi203,Stat1,Filip1l,Ifi204,Tnfaip2,Thbs1,Serpinb2,Cdkn1a |
| 6.177e-11 | -23.51 | RADAEVA_RESPONSE_TO_IFNA1_UP | MSigDB lists | RADAEVA_RESPONSE_TO_IFNA1_UP | 60 | 23 | 15632 | 1249 |
Socs1,Isg15,Psme1,Adar,Eif2ak2,Ifit2,Ifit1bl1,Rsad2,Casp3,Ifi44,Irf1,Cxcl10,Ifi35,Casp7,Stat1,Oas1g,Vcam1,Tnfsf10,Irf7,Ifit1bl2,Oas1a,Ube2l6,Plscr1 |
| 6.242e-11 | -23.50 | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | 135 | 36 | 15632 | 1249 |
Pnp2,Il6,Peli1,H2-Q6,Cd40,Bcl6,Spn,H2-Q4,Syk,Cd38,Il15,Ccdc88b,Cd80,Cd74,Irs2,H2-Q7,Nck1,Bst1,Il12rb1,Icosl,Csf1,Cd274,Cd86,Ccl5,Il1b,Cdkn1a,Clcf1,Vcam1,Kitl,Il12b,Lyn,Il18,Ebi3,Cd55,Tnfsf4,Ripk2 |
| 6.596e-11 | -23.44 | GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | MSigDB lists | GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 1382 | 177 | 15632 | 1249 |
Tnc,Errfi1,Tnf,Klf6,Tnfaip3,Rab10,Fzd1,Inhba,Rapgef2,Sh3bp4,Gdf15,Ccl5,Pde4b,Fosb,Atp6v1d,Ppp1r15a,Asns,Flrt2,Vcam1,Ppp2r2a,Trib3,Ifnb1,Ass1,Syk,Nr4a1,Dnaja1,Irs2,Sdc1,Med13,Slc9a1,Nfkb1,Plod2,Casp8,Polr2g,Jak2,Pmepa1,Cdkn1a,H3f3b,Ptk2,Max,Lyn,Rhoq,Pde1b,Nr3c1,Acvrl1,Acvr1,Lrp4,Casp1,Dusp1,Timp1,Psmb9,Bmp2,Nod1,Daxx,Pml,Sphk1,Sell,Icam1,Btg2,Junb,Il1rn,Ptgs2,Il6,Nqo1,Sdc2,Ccl12,Slc7a11,Cx3cr1,Nfkbia,Jun,Pde3b,Gclc,Plau,Il4ra,Phip,P2ry2,Il10,Hcls1,Prkar2b,Igf1r,Socs3,Tnfsf4,Acsl1,Stat3,Mecp2,Plod3,Stat5a,Homer1,Gnb4,Irak3,Pdgfc,Apaf1,Cd38,Fabp3,F11r,Stxbp3,Mmp13,Gja1,Pdgfrb,Gcnt2,Htr2b,Il1b,Keap1,Hmox1,Gng4,Ripk2,Nr4a3,Mmp14,Pla2g4a,Klf3,Cited2,Ptpn2,Tspo,Col4a2,Ahr,Me1,Spred1,Fas,Nr1h3,Kat2b,Zeb1,Rnf14,Cav1,Pid1,Gfpt1,C3,Hmgcs1,Cpeb4,Egr3,Egr2,Fut8,Casp3,Mdm2,Ccnd1,Kdm5b,Src,Ehd1,Birc2,Rbbp8,P2ry12,Notch1,Mthfr,Ier2,Agtrap,Socs1,Hif1a,Pdgfb,Nampt,Klf2,Thbs1,Bambi,Gng12,Ldha,Ptger4,Ptafr,Serpinb9,Lox,Prkce,Edn1,Nod2,Flrt3,Ezr,Zyx,Fos,Gng11,Htr2a,Atp2b4,Egr1,Jag1,Sirt1,Ltbp2,Ccne1,Casp4,Ptch1,Socs7,Stat1,Adrb2 |
| 6.667e-11 | -23.43 | GSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN | MSigDB lists | GSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN | 182 | 43 | 15632 | 1249 |
Pdss1,Ociad1,Trim21,Vasp,Pde7b,Lnpep,Snx10,Tor3a,Mov10,Nfkb2,Ikbke,Slfn9,Notch2,Keap1,Lacc1,Denr,Atp10a,Usp31,Etnk1,Fam111a,Lyn,Serpinb9,Rcan1,Osgin2,Dusp2,Slfn8,Mdn1,Parp14,Dhx58,Nfkbie,Arhgap26,Plekhf2,Klf3,Dync1h1,Rhbdf2,Itpr1,Swap70,Lpcat2,1600014C10Rik,Daxx,Tlr6,Fas,Dcp2 |
| 6.667e-11 | -23.43 | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_UP | 182 | 43 | 15632 | 1249 |
Gtpbp2,Il15ra,Serpinb9,Map3k8,Il12b,Cxcl10,Tlr1,Car13,Uba7,Brwd3,Asns,Lad1,Crim1,Prpf38a,Slco3a1,Fabp3,Dbnl,Lztfl1,Clcf1,Rap2c,Cd300lf,Rgs1,Tmem219,Vrk2,Endod1,Tmod3,Asb13,Akt3,Htra1,Lap3,Ogfr,Hdc,Rras2,Sgcb,F10,Cyth3,Edn1,Dusp2,Gadd45b,Sqstm1,Sbds,Ccl12,Spic |
| 6.750e-11 | -23.42 | HAN_JNK_SINGALING_UP | MSigDB lists | HAN_JNK_SINGALING_UP | 33 | 17 | 15632 | 1249 |
Ccnd2,Usp18,Tgfbi,Lox,Gbp3,Cxcl10,Ifit3b,Isg15,Dusp16,Ifit3,Jun,Dusp1,Ifit1bl1,Ifit1bl2,Ccl5,Ube2l6,Tnc |
| 7.032e-11 | -23.38 | MAHAJAN_RESPONSE_TO_IL1A_UP | MSigDB lists | MAHAJAN_RESPONSE_TO_IL1A_UP | 76 | 26 | 15632 | 1249 |
Il1b,Il15ra,Thbs1,Serpinb2,Tnfaip2,Kdr,Cxcl1,Acvr1b,Pim2,Oasl1,Stat1,Cxcl2,Adora2a,Stat4,Isg20,Ccl5,Slc16a1,Sdc1,Il1a,Mafk,Il6,Myc,Sod2,Ifit2,Dusp1,Flt1 |
| 7.032e-11 | -23.38 | GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | MSigDB lists | GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | 76 | 26 | 15632 | 1249 |
H2-Q6,Bcl6,Hsph1,H2-Q4,Syk,Ap3b1,Irf4,Pnp2,Il6,Il4ra,Nlrp3,H2-Q7,Hlx,Tnfrsf14,Cd83,Il27,Cd80,Cd86,Il12rb1,Irf1,Il12b,Il18,Ebi3,Cd55,Tnfsf4,Ripk2 |
| 7.248e-11 | -23.35 | DAUER_STAT3_TARGETS_UP | MSigDB lists | DAUER_STAT3_TARGETS_UP | 46 | 20 | 15632 | 1249 |
Atf3,Socs3,C3,Dusp5,Stat2,Icam1,Trib1,Pfkfb3,Ldlr,Thbs1,Slc4a7,Sod2,Ccl12,Bcl6,Jun,Stat3,Flnb,Zfp36,Maff,Cebpd |
| 7.272e-11 | -23.34 | PASINI_SUZ12_TARGETS_DN | MSigDB lists | PASINI_SUZ12_TARGETS_DN | 285 | 57 | 15632 | 1249 |
Thbs1,Gng12,Serpinb9,Phlda1,Pdlim7,Btg2,Pdgfb,Csrp1,Dusp6,Myadm,Plk2,Bmp2,Gbp2,Ube2e1,Glipr2,Errfi1,Klf6,Axl,Dusp1,Idi1,Tmem123,Rbms1,Cdkn1a,Filip1l,Kif5c,Dyrk2,Ier3,Trib1,Csf1,Stx6,Jag1,Abtb2,Plod2,Cav1,Sema3c,Rras2,Rnd3,Dusp14,Klf7,Lrp8,Palld,Irs2,Prnp,Phip,Sdc1,Myc,Mmp14,Dusp4,Vcan,Itgav,Tagln,Flrt3,Cnn2,Spsb1,Zyx,Cited2,Jun |
| 7.443e-11 | -23.32 | regulation of viral genome replication | biological process | GO:0045069 | 94 | 27 | 20694 | 1406 |
Zc3h12a,Ifitm1,Isg15,Notch1,Oas1b,Zc3hav1,Resf1,Larp1,Stau1,Ccl5,Adar,Oas1g,Ifnb1,Oas3,Plscr1,Parp10,Isg20,Apobec3,Oas1a,Slpi,Eif2ak2,Fam111a,Tnf,Oasl1,Oasl2,Rsad2,Shfl |
| 7.443e-11 | -23.32 | antigen processing and presentation | biological process | GO:0019882 | 94 | 27 | 20694 | 1406 |
Rab32,H2-T10,H2-T22,Relb,Rab10,Tap2,H2-Q4,H2-Q7,Icam1,H2-T24,Psme1,Cd74,Tap1,H2-Aa,Psme2,H2-Eb1,Ap3b1,Treml4,Fcgr1,Psmb9,H2-M2,H2-Ab1,Psmb8,H2-Q6,Tapbp,Tapbpl,Fcgr2b |
| 7.667e-11 | -23.29 | GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_WITH_EGR2_DELETED_UP | MSigDB lists | GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_WITH_EGR2_DELETED_UP | 169 | 41 | 15632 | 1249 |
Fscn1,Cd300lf,Rgs1,Fam20c,Tnfaip2,Cdkn1a,Snn,Mtmr14,Cd55,Osgin2,Rab20,Pdgfb,Icosl,Slc7a5,Psme2,Ampd3,Nfkbid,Wars,Mmd,AA467197,Tbc1d13,Birc3,Myadm,Cd274,Cd83,Col4a2,Chmp4b,Marcksl1,Itga4,Upp1,Gbp3,Sat1,Tbc1d1,S1pr2,Mlkl,Acvrl1,Dusp1,Hivep2,Ccl12,Rhbdf2,Cd40 |
| 7.667e-11 | -23.29 | GSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_UP | MSigDB lists | GSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_UP | 169 | 41 | 15632 | 1249 |
Wars,Maff,Ube2l6,Zfp36,Irf8,Lap3,Psmb8,Csrp1,Hk1,Gch1,Il15ra,Trafd1,Jak2,Cxcl1,Ldlr,Ralgds,Tnfaip2,Irf1,Pim1,Arid5b,Cdc42ep4,Mthfd2,Casp7,Dram1,Ripk2,C3,Itpkc,Cebpd,Gclm,Stat3,Cish,Psmb9,Morc3,Sod2,Ccl12,Il15,Icam1,Psmb10,Socs1,Fas,Rars |
| 7.772e-11 | -23.28 | macromolecule modification | biological process | GO:0043412 | 2576 | 256 | 20694 | 1406 |
Ccnd2,Pgap2,Dusp1,Acvr1b,Kdm4a,Saa3,Dusp8,Lox,Sap30,Otud1,Fbxo4,Plk2,Thbs1,Prdm9,Ube2l6,Grk3,Bmp2,Ubr4,Itgav,Tlr3,Ccnd1,Cdk5r1,Prkce,Keap1,Ppm1l,Ppp2r5a,Mlkl,Mdm2,St3gal5,Btg2,Extl2,Il1b,Dtx2,Acp2,Tmtc2,Isg15,Sla,Pim3,Ppp2r3a,Trib3,Mapkapk2,Mppe1,Tet2,Kdr,Dusp6,Setdb2,Egr2,Phlpp2,Gfpt1,Sik3,Ubash3b,Mdfic,Rffl,Acvrl1,Met,Myd88,Serp1,Nck1,Rnf19a,Uba7,Trim56,Ext1,Kmt5a,Ube2e2,Fut8,Ppp1r15a,Plod3,Dusp4,Kdm6b,Cnot4,Mark2,Plod2,Flt1,Usp12,P4ha2,Pdgfb,Lif,Dpy19l1,Ikbke,Ube2e1,Peli1,Src,Parp12,Hck,Pdk3,Trim12c,Map2k1,Tpst1,Jak2,Bcor,Usp35,Hat1,Sphk1,Tyk2,Adar,Ripk3,Trib1,Tnfaip3,Rictor,Il12rb1,Spsb1,Rnf139,Ranbp2,Akt3,Znrf3,Apobec3,Rnf34,Arid4a,Usp31,Mecp2,Dcun1d3,Herc6,Hopx,Eif2ak2,Ppm1k,Map3k8,Trim12a,Stat5a,Ascc3,Parp8,Med21,Tlr9,Arrdc4,St3gal1,Scyl2,Birc3,Parp14,Birc2,Dusp16,Ifih1,Dusp14,Nupr1,Il15,Ccng2,Ptpn2,Pdgfrb,Myc,Kdm5b,Prkx,Prag1,Ppp4r2,Rnf19b,Ptk2,Atm,Ddx4,Ankib1,Mgat1,Mmd,Ksr1,Sde2,Cdyl,Dusp5,Dusp2,Ppp2r2a,Htr2b,Usp18,Trim30a,Parp11,Lyn,Osm,St3gal3,Sirt1,Fam20c,Ctu1,Arf4,Arel1,Trim13,Axl,Stat4,Rnf135,Syk,Tnf,Mapkbp1,Plk3,Trim36,Pcgf5,Bfar,Eya4,Ccnj,Ccl12,Parp10,St3gal6,Pim2,Pml,Dr1,Map3k6,Fgr,Vrk2,Igf1r,Ccl5,Hk1,Uchl1,Kat2b,Jmjd6,Malt1,P4ha1,Rnf31,Dusp28,Parp3,Traf2,Usp25,Nek6,Nos2,Rnf14,Ripk2,Mul1,Parp9,Stk40,Irgm2,Dyrk2,Gcnt2,Map4k4,Trmt1l,B3gnt5,Tlk2,Ptprj,Ccne1,Jarid2,Crbn,Znrf1,Vcpip1,Pim1,Usp53,Tlr2,Plpp1,Zc3h12a,Il18,Tiparp,Irak2,Usp42,Tgs1,Ptger4,Naa25,Egln3,Klhl25,Pigv,Phlpp1,Hdac1,Acvr1,Ppp1r15b,Map2k4,S100a8,Trim21,Socs7,Nsd3,Ube2f,Irf4,Ep400,Zfp36,Irak3,Dtx3l,Ccr3,Morc3,Cop1,Mtmr14,Sgk3 |
| 7.914e-11 | -23.26 | GSE360_T_GONDII_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_T_GONDII_VS_M_TUBERCULOSIS_DC_DN | 176 | 42 | 15632 | 1249 |
Ifi35,Lpar1,Ifit3b,Acsl1,Lyn,Bcl2a1a,Tnfaip2,Ccl4,Glrx,S100a8,Psmb8,Gch1,Dusp6,Myo1b,Ifit3,Ube2l6,Isg20,Trim21,Trim14,St3gal5,Psme2,Kctd12,Uba7,Atf3,Myd88,Prdx1,Fcgr1,Cd14,Cd38,Etv5,Tap1,Ccl12,Casp1,Bcl2a1b,Psmb9,Fos,Ptpn2,Mafk,Arhgap26,Sdc2,Psma6,Bcl2a1d |
| 8.056e-11 | -23.24 | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 183 | 43 | 15632 | 1249 |
Chmp4b,Tnfrsf14,Olr1,Bcor,Hmga1,Gadd45b,Hivep2,Bcl2a1b,Sod2,Ier3,Stat4,Stx6,Zc3h7a,Ampd3,Gna15,Tnfaip3,Cd83,Sav1,Nfkbie,Kdm5b,Ccng2,B3gnt5,Bcl2a1d,Rab21,Slc15a3,Zmynd15,Eno1,Serp1,Plaur,Snn,Ptges,Zhx2,Bcl2a1a,Snapc1,Grina,Slc43a3,Il2rg,Zc3h12a,Nfkbid,Maff,Arl5b,Rgl1,Pde4b |
| 8.056e-11 | -23.24 | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP | 183 | 43 | 15632 | 1249 |
Rnf19a,Ccrl2,Ksr1,Sik3,Plekha2,Gfi1,Cflar,Idi1,Cacnb3,Tnip3,Sema4a,Chst11,Slfn8,Dusp2,Prkce,Ezr,Spn,Atp2b4,Abr,Fas,Mapkapk2,Lrp8,Wdfy1,Slfn4,Pde4b,Slfn3,Slfn9,Fcho2,Spire1,Glipr2,Gpr68,Stk40,Nr3c1,Rhbdf2,P4ha2,Dpy19l1,Ncoa7,Ripk3,Tnfaip3,Nod1,Slco3a1,Rnf135,Aim2 |
| 8.056e-11 | -23.24 | GSE15330_LYMPHOID_MULTIPOTENT_VS_PRO_BCELL_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_PRO_BCELL_DN | 183 | 43 | 15632 | 1249 |
Hif1a,Zfp281,Prdm1,Batf,1600014C10Rik,Mafk,Tbc1d1,Pnp2,Cox18,Osgin2,Serpinb9,Traf3ip2,Zc3h12a,Ldha,Dnaja2,Clic4,Nampt,Pde4b,Maff,Stxbp3,Tlr1,Ccnd2,Pgs1,Rbl1,Samhd1,Parp9,Irf4,Tor1aip2,Gpr35,Ms4a6d,Ifi35,Cd200,Socs3,Vrk2,Frmd6,Jak2,Adam19,Ogfr,Casp4,Psmb8,Rnf14,Rnf19a,Pdss1 |
| 8.056e-11 | -23.24 | GSE10325_CD4_TCELL_VS_MYELOID_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_MYELOID_DN | 183 | 43 | 15632 | 1249 |
Rhoq,Slc15a3,Sat1,Nfkbie,Fgl2,Rin2,Syk,Slc16a3,Dhrs9,Rab32,Rhbdf2,P2ry13,Bcl6,Dse,Msr1,Myd88,Hck,Clcn5,Tlr6,Hhex,Fgr,Icam1,Kmo,Htra1,Slc2a6,Wars,Plek,Ccr1,Slc31a2,Snx10,Irf8,Cd86,Clic4,Notch2,Cdkn1a,Plaur,Il13ra1,H2-Ab1,Mtmr14,Lyn,Trib1,Slc43a3,Adora2b |
| 8.096e-11 | -23.24 | GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN | 190 | 44 | 15632 | 1249 |
Slc31a1,Zhx2,Dusp28,Txn1,Flrt2,Lad1,Med21,Gpr132,Rilpl1,Aim2,Atp11a,Jmjd6,Agtrap,Myo10,Armcx6,Usp53,Itpr1,Ttc39c,Dse,Oaf,Rab21,Tbc1d1,Dennd1b,Cish,Rnf24,Dock10,Trib1,Cacna1d,Tmem67,Tmem219,Zeb1,Spen,Plscr1,Ciapin1,Pikfyve,Olr1,Trim36,Crbn,Ezr,Plac8,Ccl12,Tspan3,Katna1,Ppfia3 |
| 8.104e-11 | -23.24 | DEATH-like_dom_sf | interpro domains | IPR011029 | 84 | 26 | 19984 | 1430 |
Cflar,Ifih1,Nod1,Mefv,Ripk2,Apaf1,Ifi203,Birc3,Card6,Nfkb2,Casp8,Mndal,Casp1,Fas,Irak3,Casp4,Malt1,Myd88,Nlrc4,Nfkb1,Casp2,Nlrp3,Birc2,Nod2,Aim2,Irak2 |
| 8.549e-11 | -23.18 | GO_REGULATION_OF_PROTEOLYSIS | MSigDB lists | GO_REGULATION_OF_PROTEOLYSIS | 648 | 100 | 15632 | 1249 |
Spint2,Serpine1,Ppp1r15a,Keap1,Il1b,Plat,Trib3,Psmb6,Prdx5,Tlk2,Cycs,Stat3,Ifi209,Traf2,Tnf,Apaf1,Rnf34,Psmb10,Rnf139,Plk3,Aim2,Egln3,Slpi,Psme2,Ifi211,Trim21,Casp8,Mndal,Cav1,Rnf14,Tnfrsf1b,Atm,S100a8,Dnajb2,Fam162a,Jak2,Trib1,Ifi204,C3,Mmp9,Ptk2,Ift57,Mmp14,Ctsc,Nlrc4,Rnf114,Ifi207,Mul1,Ifi214,Cdkn2d,Fas,Tnfsf15,Ifi208,Inpp5b,Plk2,Plaur,Thbs1,Tnfsf10,Serpinb2,Serpinb9,Smc5,Rnf19b,Cd55,Psma6,Mdm2,Rffl,Casp3,Ifi205,Birc2,Psmb9,Timp1,Casp1,Cst7,N4bp1,Ifi213,Dusp1,Src,Crim1,Nod1,Pml,Ube2e1,Psme1,Ifi203,Casp2,Rnf19a,Sirt1,Il10,Tnfsf14,Psmb8,Ankib1,Birc3,Mefv,Casp7,Il6,Myc,Psmd10,Bcl2l11,Gclc,Nlrp3,Pttg1 |
| 8.663e-11 | -23.17 | HINATA_NFKB_IMMU_INF | MSigDB lists | HINATA_NFKB_IMMU_INF | 16 | 12 | 15632 | 1249 |
Nfkb1,Ccl12,Nfkbia,Il6,Cxcl2,Irf1,Icam1,Tnfaip2,Cd83,Cxcl1,Olr1,Il1b |
| 8.742e-11 | -23.16 | GO_RESPONSE_TO_OXYGEN_LEVELS | MSigDB lists | GO_RESPONSE_TO_OXYGEN_LEVELS | 294 | 58 | 15632 | 1249 |
Plau,Egr1,Fas,Cx3cl1,Mmp14,Prkce,Edn1,Bnip3,Sdc2,Ccl12,Flt1,Cited2,Cdkn1a,Fam162a,Socs3,Nox1,Cpeb4,Adrb2,Lpar1,Slc9a1,Egln3,Sirt1,Atm,Pdk3,Plod2,Nos2,Cav1,Bmp2,Notch1,Cd38,Daxx,Apaf1,Mthfr,Pml,Plk3,Agtrap,Hif1a,Icam1,Casp3,Mecp2,Mdm2,Casp1,Src,Birc2,Itpr1,Thbs1,Plat,Vcam1,Il1b,Ldha,Hmox1,Ptgs2,Ddit4,Pdgfb,Mmp13,Vasn,Pdgfrb,Ppp1r15a |
| 8.816e-11 | -23.15 | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_48H_DN | 143 | 37 | 15632 | 1249 |
Timp1,Bcl6,Jun,Plac8,P4ha2,Ifit2,Bcl2a1b,Rsad2,Bcl2a1d,Gpr68,Stat3,Ntng2,Cyth3,Isg15,Socs1,Znrf3,Atf3,Egr1,Csrnp1,Mthfr,Rgs3,Klf7,Pde3b,Igsf9,Dcun1d3,Tbc1d13,Etv6,Phlda1,Tnfsf15,Phyh,Parp11,Tnfsf4,Dnajb2,Cmpk2,Gfi1,Bcl2a1a,Irak2 |
| 9.063e-11 | -23.12 | positive regulation of mononuclear cell proliferation | biological process | GO:0032946 | 136 | 33 | 20694 | 1406 |
Cdkn1a,Tnfsf4,Cd86,Spn,Tlr9,Nck1,Cd38,Icosl,Myd88,Tnfsf9,Peli1,Stat5a,Ripk2,Cd80,Syk,Il6,Bst1,Cd74,Ccdc88b,Cd274,Il1b,Il12b,Bcl6,Il18,Itgal,Irs2,Il12rb1,Il15,Clcf1,Ccl5,Csf1,Cd40,Vcam1 |
| 9.063e-11 | -23.12 | lymphocyte mediated immunity | biological process | GO:0002449 | 136 | 33 | 20694 | 1406 |
Raet1e,Jag1,Prdx1,Fcgr1,Treml4,Myd88,Batf,Icosl,H2-Ab1,H60b,Il18rap,Stx11,Fcgr2b,Ctsc,Nod2,Il4ra,Irf7,Fas,Icam1,C1rl,Dennd1b,Serpinb9,Pou2f2,Fgl2,Il18,Swap70,C3,Cd55,Cd74,C1ra,Rnf19b,Il12b,Serpinb9b |
| 9.112e-11 | -23.12 | TLR4 (Toll-like receptor 4) signaling pathway | Lipid Maps pathways | TLR4 | 67 | 34 | 416 | 80 |
Irak3,Nfkb2,Myd88,Ccl5,Il1b,Ifna1,Ikbkg,Ikbke,Fos,Map2k4,Icam1,Ccl3,Vcam1,Ptgs2,Nfkbib,Tab2,Nfkbia,Nfkb1,Ccl4,Map3k8,Tnfaip3,Jun,Nfkbie,Relb,Ifnb1,Casp8,Cd14,Rel,Il1a,Map2k1,Nos2,Il6,Irf7,Tnf |
| 9.150e-11 | -23.11 | GO_POSITIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 212 | 47 | 15632 | 1249 |
Trim14,Trim21,Nfkbib,S100a8,Rnf31,Nfkb1,Ikbkg,Il10,Cflar,Jak2,Tlr9,Mtdh,Tlr2,Il6,Nod2,Nfkbia,Eif2ak2,Nlrc4,Lrp8,Trim13,Nlrp3,Trim26,Fzd1,Nfkb2,Irak2,Il1b,Tlr3,Ripk2,Arid5b,Psma6,Tnf,Traf2,Hspa1a,Cd40,Nod1,Traf5,Sav1,Ripk3,Irak3,Malt1,Aim2,Ddx58,Icam1,Tab2,Traf1,Trim12c,Sphk1 |
| 9.286e-11 | -23.10 | AMIT_EGF_RESPONSE_40_HELA | MSigDB lists | AMIT_EGF_RESPONSE_40_HELA | 42 | 19 | 15632 | 1249 |
Btg2,Il6,Zfp36,Dusp2,Ppp1r15a,Klf2,Jun,Klf6,Nr4a1,Dusp1,Junb,Ldlr,Ptgs2,Ier3,Ier2,Egr3,Atf3,Egr1,Dusp5 |
| 9.385e-11 | -23.09 | Leishmaniasis | KEGG pathways | ko05140 | 65 | 25 | 7931 | 713 |
Fos,Itga4,Myd88,H2-Ab1,Il1a,Jak2,C3,Tab2,Il1b,H2-Eb1,Il12b,Fcgr4,Fcgr1,Marcksl1,Tlr2,Nos2,Stat1,Jun,Nfkb1,Nfkbia,Ptgs2,Tnf,Nfkbib,H2-Aa,Il10 |
| 9.385e-11 | -23.09 | Leishmaniasis | KEGG pathways | mmu05140 | 65 | 25 | 7931 | 713 |
Fos,Itga4,C3,Tab2,Il12b,H2-Eb1,Il1b,Myd88,Jak2,Il1a,H2-Ab1,Fcgr1,Fcgr4,Tlr2,Nos2,Marcksl1,Jun,Nfkb1,Stat1,Ptgs2,Nfkbib,Tnf,Nfkbia,H2-Aa,Il10 |
| 9.397e-11 | -23.09 | purine ribonucleoside triphosphate binding | molecular function | GO:0035639 | 1707 | 187 | 20217 | 1400 |
Itpkc,Rhoq,Rab21,Gbp7,Cmpk2,Apaf1,Gclc,Trib1,Grk3,Tent4a,Gch1,Wars,Pim3,Ep400,Abcc1,Ube2e2,Oasl1,Actb,Rab32,Srxn1,Dync1h1,Fgr,Pgs1,Hk1,Map2k4,Rars,Met,Jak2,Gbp8,Arl4a,Asns,Nkiras1,Dhx58,Mcm9,Tent2,Hck,Acsl1,Tap2,Gem,Gna15,Mark2,Kif9,Pim2,Kif3c,Rhou,Ripk3,Syk,Mapkapk2,Prkx,Pdgfrb,Mov10,Acsl5,Ifih1,Eif2ak2,Mcm6,Rab20,Irak2,Ascc3,Oasl2,Acvr1,Hspa1b,Akt3,Ube2e1,Scyl2,Ass1,Tap1,Vrk2,Nod1,Helz2,Gbp2,Etnk1,Rhoh,Gbp3,Ift22,Mocs1,Slfn9,Ube2f,Papss2,Rab9,Rhof,Tor3a,Samhd1,Nlrp3,Map4k4,Rab10,Rhoc,Pdk3,Pim1,Gmppb,Sphk1,Ddx58,Stk40,Tuba4a,Smc5,Flt1,Hcar2,Ksr1,Oas3,Pikfyve,Cenpe,Irgm1,Dyrk2,Rac3,Ptk2,Atp2b4,Dgka,Katna1,Nlrc5,Plk2,Sik3,Dnaja2,Atp13a1,Atp11a,Prkce,Lyn,Arl5b,Chd9,Trip13,Ddx4,Abcb1a,Nod2,Gbp9,Dck,Axl,Tgtp1,Gbp2b,Swap70,Atm,Pik3cd,Hsph1,Mx1,Iigp1,Rras2,Acvr1b,Sgk3,Rap2c,Irgq,P2ry2,Igf1r,Slfn8,Fam20c,Hspa2,Src,Gk,Arl5c,Ehd1,Ube2l6,Ciita,Irak3,Ak4,Abcc5,Mthfd1l,Arf4,Tlk2,Gtpbp2,Rab19,Trib3,Oas2,Tyk2,Atp10a,Kdr,Ripk2,Clcn5,Clcn7,Myo10,Cgas,Map2k1,Hk3,Hspa1a,Rnd3,Map3k8,Hk2,Pcx,Nek6,Dnaja1,Mlkl,Pfkl,Acvrl1,Map3k6,Ikbke,Plk3,Prag1,Pgk1,Myo1b,Nlrc4,Slfn5,Rnd1 |
| 9.558e-11 | -23.07 | lymphocyte differentiation | biological process | GO:0030098 | 272 | 50 | 20694 | 1406 |
Ifna1,Pou2f2,Plcl2,Hhex,Rhoh,Axl,Ripk3,Clcf1,Clec4d,Clec4e,Gpr18,Ahr,Relb,Tnfaip3,Stat3,H2-Ab1,Spn,Tnfsf8,Dock10,Ptprj,Sema4a,Ifna5,Atm,Il6,Bcl2a1d,Ifna4,Ptpn2,Fzd5,Malt1,Irf4,Gadd45g,Bcl6,Il12b,Cd74,Fas,Il15,Egr1,Jmjd6,Ifnb1,Notch2,Irf1,Batf,Ikzf1,Ifna6,Slamf8,Ifna2,Syk,Ptger4,Stat5a,Rsad2 |
| 9.592e-11 | -23.07 | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | 177 | 42 | 15632 | 1249 |
Zc3h12a,C3,Ldha,Casp7,Ifi35,Fpr1,Irf1,Aida,Plat,Serpinb2,Il1rn,Cacna1d,Jak2,Trafd1,H3f3b,Plaur,Rcl1,Rabgef1,4930523C07Rik,Snx10,Myo1b,Tap2,Alas1,Hk2,Palld,Atf3,Nlrp3,Papss2,Sav1,Irak3,Ahr,Gadd45b,Slc25a37,Cd40,Rhoq,Edn1,Hspa2,Psma6,Dhx58,Nfkbie,Optn,Ogfrl1 |
| 9.660e-11 | -23.06 | regulation of angiogenesis | biological process | GO:0045765 | 307 | 54 | 20694 | 1406 |
Il1a,Cx3cl1,Tcf4,Kdr,Vegfc,Pde3b,Mecp2,Pml,Il10,Cx3cr1,Ccl2,Col4a2,Acvrl1,Adrb2,Pf4,Rgcc,Ccl5,Spry2,Serpine1,Wars,Klf2,Cd40,Mtdh,Ccr3,Itgb8,C3,Ptgs2,Itga5,Hif1a,Flt1,Cxcl10,Spred1,Lif,Sema4a,Stat3,Cd34,Plk2,Thbs1,Hmox1,Cysltr2,Pgk1,Stat1,Hk2,Tlr3,Sphk1,Hhex,Notch1,Hmga2,Il1b,Pik3r6,Akt3,Sirt1,Mmp9,Zc3h12a |
| 9.670e-11 | -23.06 | GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_UP | MSigDB lists | GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_UP | 150 | 38 | 15632 | 1249 |
Socs1,Irs2,Stat2,Plk3,Gbp2,Tnfaip3,Ahr,Slfn5,Atp11b,Slc48a1,Tspo,Crlf3,Sgcb,Tet2,N4bp1,Dock10,Tapbp,Nqo1,Rffl,Fchsd2,Parp14,Ifit3b,Azi2,Trafd1,Ccl4,Jak2,Irf7,Ifit3,Rnf31,Brd2,Jarid2,Slc31a2,Xaf1,Wars,Zeb1,Gpr132,Tmeff1,Zc3h7a |
| 9.670e-11 | -23.06 | HALLMARK_UV_RESPONSE_UP | MSigDB lists | HALLMARK_UV_RESPONSE_UP | 150 | 38 | 15632 | 1249 |
Alas1,Btg2,Rasgrp1,Ccne1,Tuba4a,Gch1,Eno2,Junb,Fosb,Asns,Cnp,Cxcl1,Lhx2,Stip1,Hmox1,Lyn,Irf1,Grina,Il6,Nat2,Mmp14,Casp3,Abcb1a,Hspa2,Sqstm1,Sod2,Bcl2l11,Nr4a1,Nfkbia,Mgat1,Dnaja1,Fos,Bmp2,Tap1,Mark2,Atf3,Nxf1,Icam1 |
| 9.717e-11 | -23.05 | GSE43955_1H_VS_10H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_1H_VS_10H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 184 | 43 | 15632 | 1249 |
Hlx,Usp18,Relb,Txnrd1,Csf3r,Cp,Dbnl,Top3a,Fgl2,Rcan1,Clic4,Igf2bp2,Il1b,Glrx,Slc7a8,Gja1,Irf7,Pdgfb,Stxbp3,Col18a1,Col4a2,Tap1,Olr1,Nr4a1,Plac8,Sod2,Cyfip1,Cxcl14,Ifi35,Kif5c,Dck,Ifit3b,Lyn,Gpd2,Frmd6,Pdk3,Ltbp2,Ifit3,Il10,Zc3h12c,Cnn3,Flnb,Tmem176a |
| 9.717e-11 | -23.05 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_DN | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_DN | 184 | 43 | 15632 | 1249 |
Mcm6,Casp7,Endod1,Cd200,Dusp5,Nfil3,Glrx,Gfi1,Sh3bgrl2,Tnip1,Irak2,Adam19,Ralgds,Lad1,Hopx,Jdp2,Il12rb1,Hivep3,Stx11,Trim14,Ube2l6,Phlda1,Trip13,Prnp,Icam1,Mxd1,Etv5,Mdfic,Nod1,Cd83,Cyfip1,Tspan3,Axl,Src,Stat5a,Nfkbia,Cst7,Phlpp1,Gadd45g,Dusp4,Gpr68,Irf4,Egr2 |
| 9.717e-11 | -23.05 | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | 184 | 43 | 15632 | 1249 |
Hat1,Ccrl2,St3gal5,Rel,Birc3,Dusp16,Fscn1,Tlr2,Acsl1,Cacnb3,Slc44a1,Abcb1a,Pla2g4a,Ctsc,B4galt4,Trim36,Lpcat2,Nmral1,Tyk2,Vasp,Pdgfb,Il1b,Acp2,Serpinb2,Gca,Irak2,Rcan1,Adora2b,Slc31a1,Tlr3,Cebpd,Dock10,Cdyl2,Cd40,Apobec3,Lipe,Rgs3,Ube2f,Bmp2,Nod1,Magohb,Malt1,Ube2e1 |
| 9.723e-11 | -23.05 | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN | 191 | 44 | 15632 | 1249 |
Ccl5,Myadm,Snx10,Eya4,Map3k8,Serpinb9,Traf3ip2,Glrx,Il15ra,Cldnd1,Plat,Bcl2a1a,N4bp1,Plekha5,Cst7,Casp1,Bcl2a1d,Fgl2,Errfi1,Cish,St3gal6,Traf1,Mcoln2,Prdm1,Mdfic,Casp4,Irf8,Tnfrsf1b,Il18rap,Kctd12,Plscr1,Ier3,Sema4a,Odc1,Ell2,Ccl4,Cyfip1,Bcl2a1b,Gclm,Fcgr2b,Abcb1a,Samhd1,Gpc1,Il15 |
| 9.732e-11 | -23.05 | positive regulation of T cell differentiation | biological process | GO:0045582 | 95 | 27 | 20694 | 1406 |
Il1b,Pik3r6,Nlrp3,Cd83,Lgals9,Cd74,Malt1,Il18,Bcl6,Nfkbid,Il4ra,Nfkbiz,Rasgrp1,Tnfsf4,Tnfsf9,Egr3,Ikzf1,Irf1,Socs1,Ap3b1,Hlx,Ripk2,Stat5a,Il2rg,Il6,Syk,H2-Aa |
| 9.819e-11 | -23.04 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE | 77 | 26 | 15632 | 1249 |
Bcl2l11,Bcl2a1b,Ifi213,Tnf,Ifi205,Ifi209,Bcl2a1d,Pml,Nupr1,Ifi214,Ifi207,Tnfrsf1b,Atm,Mndal,Ifi208,Ifi211,Ddit4,Casp2,Ifi203,Sirt1,Dyrk2,Hmox1,Ifi204,Ikbke,Bcl2a1a,Cdkn1a |
| 1.060e-10 | -22.97 | PID_IL27_PATHWAY | MSigDB lists | PID_IL27_PATHWAY | 26 | 15 | 15632 | 1249 |
Stat2,Il12b,Il18,Ebi3,Stat1,Il1b,Il27,Jak2,Tnf,Stat5a,Stat4,Il12rb1,Tyk2,Stat3,Il6 |
| 1.085e-10 | -22.94 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | 131 | 35 | 15632 | 1249 |
Angpt1,Palld,Ddx60,Isg15,Ifih1,Usp18,Ddx58,Ifi44,Abcb1a,Rsad2,Rbpms,Ifit1bl1,Eif2ak2,Ifit2,Oas3,Gpr18,Thbs1,Prkar2b,Epsti1,Oas1g,Stat1,Herc6,Ifit3b,Ptgs2,Ddit4,Xaf1,Oas2,Oas1a,Gja1,Gdf15,Gch1,Ifit1bl2,Irf7,Hopx,Ifit3 |
| 1.095e-10 | -22.94 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN | 164 | 40 | 15632 | 1249 |
Ptgs2,Pim1,Trib1,Mefv,Acsl1,Egr3,Socs3,Ell2,Rcl1,Trem1,Zhx2,Il1b,Cxcl1,Adam19,Serpinb2,Fosb,S100a8,4930523C07Rik,Nampt,Ccr1,Dusp6,Ccrl2,Btg2,Zfp36,Slpi,Tlr1,Fpr2,Sell,Ier2,Hlx,Tlr6,Egr1,Ehd1,Ccl12,Treml2,Irf4,Myc,Egr2,Cish,Pnp2 |
| 1.095e-10 | -22.94 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_1H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_1H_CD4_TCELL_DN | 164 | 40 | 15632 | 1249 |
Lif,Bcor,Egr1,Rtp4,Arg2,Rras2,Rnf34,Pfkfb3,Dusp14,Prpf38a,Bcl2a1b,Tnf,Nr4a1,Gpr18,Nat2,Egr2,Cish,Irf4,Bcl2a1d,Dnaja2,Cd200,Egr3,Kdm6b,Nr4a3,Ifit3b,Snapc1,Bcl2a1a,Pmepa1,Hsd17b7,Ttc9c,Med21,Gem,Tnfsf14,Ifit3,Phlda1,Pdss1,Arl5b,Tlr1,Stx6,Nfkbid |
| 1.121e-10 | -22.91 | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION | 38 | 18 | 15632 | 1249 |
Ifi205,Mndal,Ifi209,Ifi213,Gsdmd,Casp1,Ifnar1,Nod2,Ifi203,Ifi211,Ifi208,Ifi204,Ifi214,Nlrp3,Aim2,Ifi207,Jak2,Nod1 |
| 1.147e-10 | -22.89 | GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 392 | 70 | 15632 | 1249 |
Rhoh,Lif,Hhex,Socs1,Mvp,Tnfaip3,Irak3,Rgs3,Dusp1,Hsph1,Rgs14,Dusp8,Cish,Stat3,Casp3,Errfi1,Dusp5,Uchl1,Zc3h12a,Ptprj,Trib3,Il1b,Myadm,Dusp6,Samsn1,Flrt2,Ppp1r15a,Ddit4,Inhba,Cdkn2d,Atf3,Nck1,Irs2,Prnp,Kat2b,Ubash3b,Adar,Dusp14,Angpt1,Spred1,Flrt3,Gadd45b,Ezr,Ptpn2,Jun,Dnaja1,Psmd10,Stap1,Dusp2,Ppp2r5a,Myc,Il6,Spry2,Dusp4,Socs3,Lyn,Trib1,Aida,Tnip1,Cdkn1a,Socs7,Prkar2b,Pmepa1,Dusp16,Igf1r,Ppp1r15b,Rabgef1,Pid1,Cav1,Sirt1 |
| 1.147e-10 | -22.89 | HAN_SATB1_TARGETS_DN | MSigDB lists | HAN_SATB1_TARGETS_DN | 392 | 70 | 15632 | 1249 |
Mcmbp,Cd164,St3gal6,Lif,Ccng2,Hspa2,Lztfl1,Rab11fip1,Nr3c1,Oas3,Cd40,Itpr1,Casp1,Ifnar1,Ifit2,Dusp1,Il1b,Glrx,Plat,Il18,Tgfbi,Ptgs2,Ak4,Oas1g,Maff,Inhba,Tnfsf15,Antxr1,Slc2a6,Ddit4,Tuba4a,Pde4b,Tap1,Atp11b,Samhd1,Klf7,Tspo,Slc16a1,Cd34,Rnd3,Papss2,Slc30a1,Stxbp1,Cpd,Sdc2,Gpr35,Il6,Bnip3,Cited2,Ccl12,Slc7a11,Sqstm1,Flt1,Armc8,Cd82,Ifit3b,Pik3cd,Dnajb4,Lpar1,Hmgcs1,Casp7,Oas1a,Slpi,Isg20,Casp4,Plod2,Ifit3,P4ha1,Atm,Eno2 |
| 1.147e-10 | -22.89 | leukocyte activation involved in immune response | biological process | GO:0002366 | 167 | 37 | 20694 | 1406 |
Relb,Ifnb1,Tnfaip3,Notch2,Lyn,Icam1,Nr4a3,Prkce,Clec4d,Clec4e,Dnase1l3,Gadd45g,Plcl2,Fgl2,Itgal,Swap70,Ifna1,Irf4,Cd180,Il12b,Syk,Ptger4,Il6,Ifna2,Ifna5,Ifna4,Spn,Milr1,Ifna6,Stat3,Batf,Icosl,Sema4a,Cx3cr1,Stx11,Dock10,Rasgrp1 |
| 1.167e-10 | -22.87 | BURTON_ADIPOGENESIS_PEAK_AT_8HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_8HR | 47 | 20 | 15632 | 1249 |
Ifi208,Srxn1,Ifi211,Ifi203,Fgl2,Ifi213,Plac8,Hsph1,Ifi205,Mndal,Ifi209,Slc16a1,Rras2,Samhd1,Rcl1,Ifi207,Ppa1,Itga5,Ifi214,Ifi204 |
| 1.170e-10 | -22.87 | GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP | 185 | 43 | 15632 | 1249 |
Tor3a,Il18rap,Rnf19a,Trim56,Trim21,Ier3,Mppe1,Rcn1,Cd200,Dyrk2,Etnk1,Tmem123,Orai2,Jun,Gadd45g,Peli1,Parp14,Il4ra,Etv3,Ccnd2,Ubash3b,Egr1,Zbp1,Osm,Vps54,Cd274,Ppm1k,Cnp,Slc4a7,Dgka,Btg2,Grina,Epsti1,Il15ra,Inpp1,Osbpl3,Nfkbie,Rab21,Sell,Tab2,Irak3,Cd164,Crlf3 |
| 1.179e-10 | -22.86 | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | 125 | 34 | 15632 | 1249 |
Fas,Il1a,Rtp4,Myd88,Plau,Bmp2,Apaf1,Nfkbia,Casp1,Timp1,Tank,Jun,Casp3,Il6,Pnp2,Gsr,Tlr3,Casp7,Egr3,Ak4,Cflar,Idi1,Tnfsf10,Plat,Plaur,Il1b,Cdkn1a,Birc3,Ccne1,Gja1,Cav1,Pdgfrb,Btg2,Fzd1 |
| 1.193e-10 | -22.85 | regulation of autophagy | biological process | GO:0010506 | 248 | 47 | 20694 | 1406 |
Htr2b,Ikbkg,Hk2,Hmox1,Tlr2,Tnfaip3,Zc3h12a,Sirt1,Optn,Chmp4b,Trib3,Trim13,Dram1,Hif1a,Atm,Kdm4a,Mul1,Ripk2,Irgm2,Sesn3,Bcl2l11,Stat3,Plk2,Eif4g2,Map2k1,Casp1,Trim21,Mtdh,Larp1,Nupr1,Nod2,Nod1,Bnip3,Mefv,Ptk2,Kdr,Iigp1,Sh3bp4,Plk3,Tspo,Irgm1,Tlr9,Adrb2,Pim2,Il10,Pikfyve,Nampt |
| 1.211e-10 | -22.83 | GO_SINGLE_ORGANISM_CELL_ADHESION | MSigDB lists | GO_SINGLE_ORGANISM_CELL_ADHESION | 434 | 75 | 15632 | 1249 |
Nck1,Fas,Stxbp1,Egr1,Cdk5r1,Ifna1,Cd34,Il15,Cd80,Clec4e,Olr1,Ezr,Spn,Itgav,Syk,Slc7a11,Ptpn2,Irf4,Pdpn,Il6,Ifnb1,Ifna5,Tnfsf4,Ebi3,Itga5,Irf1,Pik3cd,Azi2,Sema4a,Actb,Tnip1,Nlgn2,S100a8,Tnfsf14,Itgal,Vezt,Casp8,Itga4,Malt1,Rhoh,Cd74,Icam1,Psmb10,Jmjd6,Batf,Ripk3,Ifna2,Relb,Tnf,Axl,Src,Ifnar1,P2ry12,Micall2,Tnfsf8,Sele,Treml2,Rsad2,Ptger4,Fndc3a,Ripk2,Il12b,Clec4d,Vcam1,Pkp4,Il1b,Plek,Csrp1,Ccl5,Cd86,Fzd5,Icosl,Stxbp3,Ifna6,Antxr1 |
| 1.229e-10 | -22.82 | DOANE_RESPONSE_TO_ANDROGEN_DN | MSigDB lists | DOANE_RESPONSE_TO_ANDROGEN_DN | 221 | 48 | 15632 | 1249 |
Tmem123,Rbms1,Cacna1d,Cdkn1a,Kif5c,Casp7,Plscr1,Slc9a1,Psmb8,Eno2,Heatr6,Plod2,Sema3c,Cdc42ep2,Gpc1,Samhd1,Palld,Evl,Rai14,Edn1,Dusp4,Tra2a,Psip1,H2-Q4,Thbs1,Slc29a3,Bambi,Sp110,Rtn1,Herc6,Noc4l,Oas2,Dusp6,Cdyl,Pde4b,Sipa1l1,Traf5,Asap3,H2-Q7,Arg2,Kmo,Tnc,Abcc5,Apobec3,Arhgef3,H2-Q6,Itpr1,Traf2 |
| 1.233e-10 | -22.82 | ubiquitin-like protein ligase binding | molecular function | GO:0044389 | 321 | 56 | 20217 | 1400 |
Ikbkg,Hspa1a,Triobp,Uchl1,Tpi1,Nek6,Dnaja1,Tnfrsf14,Mdm2,Dtx3l,Parp9,Cdkn1a,Ddx58,Ikbke,Isg15,H2-Ab1,Stat2,Tnfrsf1b,Traf1,Cacybp,Src,Nfkbia,Stat1,Tank,Syk,Mid1,Jun,Myc,Mul1,Sipa1l1,Ube2l6,Pml,Rnf31,Dio2,Cd40,Egr2,Prkar2b,Hspa1b,Ubash3b,Fzd5,Dnajb2,Usp25,Hif1a,Trib1,Rnf34,Traf2,Ptk2,Lyn,Caml,Trib3,Kdm4a,Casp8,Daxx,Sqstm1,Traf5,Rffl |
| 1.248e-10 | -22.80 | BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN | 30 | 16 | 15632 | 1249 |
Peli1,Ifi44,Ifi208,Ifi211,Ifi203,Ezr,Ifi213,Ifi209,Mndal,Ifi205,Ifi207,Stat1,Ptger4,Ifi214,Ifi204,Icam1 |
| 1.268e-10 | -22.79 | regulation of organelle organization | biological process | GO:0033043 | 1233 | 143 | 20694 | 1406 |
Tmsb10,Carmil1,Nupr1,Nsd3,Fas,Trip13,Sipa1l1,Stap1,Edn1,Resf1,Rhoq,Phldb1,Gda,Rac3,Rhoc,Myc,Pdgfrb,Fchsd2,Tspo,Rhou,Mecp2,Ptger4,Cenpe,Hspa1a,Lnpk,Bst1,Cenpj,Ezr,Mllt6,Plaur,Evl,Dcp2,Adrb2,Cdc42ep4,Rictor,Rnd3,Tlr2,Sphk1,Bcor,Gfi1,Rhoh,Chmp4b,Optn,Swap70,Lpar1,Mul1,Irgm2,Smc5,Tmod3,Dst,Nek6,Pdgfb,Lif,Mthfr,Hap1,Jarid2,Stat2,Tlk2,Smg7,Hcls1,Map2k1,Cdc42ep2,Src,Csf3,Hck,Bcl2l11,Notch2,Jdp2,Kat2b,Icam1,Rgcc,Fgr,Igf1r,Phip,Tmem67,Dync1h1,Parp3,Mark2,Agrn,Rnd1,Bcl6,Sec24b,Fscn1,Bnip3,Trim36,Fam162a,Tnf,Cx3cl1,Daxx,Il1a,Tpx2,Kdr,Stxbp1,Pikfyve,Pml,Arid5a,Pla2g4a,Parp10,Sdc4,Nck1,H3f3b,Irgm1,Kif9,Met,Tnfsf10,Cav1,Osm,Sdc1,Myadm,Prkce,Psmd10,Spire1,Cdk5r1,Dbnl,Hk2,F11r,Asap3,Rhof,Pttg1,Gpsm2,Pmaip1,Il1b,Ier3,Sirt1,Mmp9,Palld,Syne2,Vasp,Mid1,Cyfip1,Atm,Kdm4a,G3bp2,Higd1a,Hif1a,Ddhd1,Plk2,Hsph1,Prdm9,Whamm,Hspa1b,Fbxo4,Plek |
| 1.296e-10 | -22.77 | lipopolysaccharide-mediated signaling pathway | biological process | GO:0031663 | 34 | 16 | 20694 | 1406 |
Il1b,Ccl12,Myd88,Il18,Cd14,Malt1,Nfkbia,Irak2,Prkce,Ccl5,Tnf,Ripk2,Lyn,Ptafr,Stat1,Mtdh |
| 1.333e-10 | -22.74 | GO_MYELOID_LEUKOCYTE_DIFFERENTIATION | MSigDB lists | GO_MYELOID_LEUKOCYTE_DIFFERENTIATION | 95 | 29 | 15632 | 1249 |
Cd86,Casp8,Mndal,Junb,Snx10,Sirt1,Csf3,Ifi203,Ifi211,Csf1,Ifi208,Ifi204,Pik3cd,Mmp9,Fam20c,Ifi205,Jun,Ifi209,Ifi213,Tnf,Src,Irf4,Batf2,Pde1b,Ifi214,Hhex,Ifi207,Relb,Batf |
| 1.336e-10 | -22.74 | negative regulation of secretion by cell | biological process | GO:1903531 | 232 | 45 | 20694 | 1406 |
Cd34,Map4k4,Abr,Rhbdf2,Lif,Il6,Arg2,Lgals9,Nlrp3,Notch1,Pim3,Il1b,Sirt1,Tnfrsf1b,Zc3h12a,Osm,Tnfaip3,Klf7,Hmox1,Frmd4a,Cd200,Tlr6,Ezr,Il10,Pml,Tnfsf4,Slc30a1,Hdac1,Angpt1,Rsad2,Rab11fip1,P2ry12,Tnf,Mapkbp1,Cx3cl1,Ptger4,Pde3b,Nr1h3,Il1rn,Rgcc,Rabgef1,Srgn,Pfkl,Edn1,Stxbp3 |
| 1.362e-10 | -22.72 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP | 107 | 31 | 15632 | 1249 |
Relb,Vcpip1,Etv5,Ahsa1,Sav1,Jmjd6,Znrf3,Atf3,Mxd1,Ccng2,Ifrd1,Mafk,Rnf24,Pnp2,Casp3,Dnaja1,Hsph1,Nfil3,Plaur,Stip1,Kitl,Mafg,Spire1,Rcan1,Trib1,Cpeb4,Cxcl2,Inhba,Srxn1,Zc3h12c,Samsn1 |
| 1.365e-10 | -22.71 | GO_REGULATION_OF_LEUKOCYTE_MIGRATION | MSigDB lists | GO_REGULATION_OF_LEUKOCYTE_MIGRATION | 132 | 35 | 15632 | 1249 |
Serpine1,Tnfsf14,Ccl5,Rabgef1,Ccr1,Cxcl2,Pla2g7,Csf1,Cxcl10,Ptafr,Lyn,Hmox1,Ptger4,Il1b,Pf4,Vegfc,Thbs1,Kitl,Ccl4,Cxcl1,Cmklr1,P2ry12,Swap70,Ccl12,Tnf,Cxcl14,Stap1,Il6,Cx3cl1,Icam1,Cd74,Abr,Itga4,Ripk3,Tnfrsf14 |
| 1.374e-10 | -22.71 | positive regulation of lymphocyte mediated immunity | biological process | GO:0002708 | 138 | 33 | 20694 | 1406 |
Traf2,Il6,Raet1e,Klrk1,Tnf,Rsad2,Stat5a,H2-M2,Fcgr1,Rasgrp1,Arid5a,Tnfsf4,Il18rap,Pvr,H60b,H2-Q6,H2-T10,Cd40,Clcf1,H2-Q4,H2-Q7,Tap2,H2-T22,Nod2,Malt1,Fzd5,Il18,H2-T24,Il12b,Il1b,Nectin2,Nlrp3,C3 |
| 1.384e-10 | -22.70 | chemokine activity | molecular function | GO:0008009 | 43 | 18 | 20217 | 1400 |
Cxcl14,Cxcl1,Ccl8,Ccl12,Ccl2,Ccl22,Cxcl11,Cxcl3,Ccl5,Ccl3,Ccl9,Cx3cl1,Cxcl10,Cxcl9,Ccl7,Cxcl2,Pf4,Ccl4 |
| 1.393e-10 | -22.69 | carbohydrate derivative binding | molecular function | GO:0097367 | 2106 | 220 | 20217 | 1400 |
Mlkl,Dnaja1,Nek6,Pcx,Hk2,Map3k8,Rnd3,Tnc,Ccl5,Hspa1a,Hk3,Map2k1,Thbs1,Pnp2,Ptafr,Rnd1,Slfn5,Myo1b,Nlrc4,Pgk1,Prag1,Plk3,Ikbke,Map3k6,Cxcl10,Acvrl1,Pfkl,Rab19,Gtpbp2,Tlk2,Arf4,Mthfd1l,Tlr2,Abcc5,Ak4,Irak3,Ciita,Ube2l6,Ehd1,Cgas,Myo10,Clcn7,Clcn5,Ripk2,Kdr,Atp10a,Oas2,Tyk2,Trib3,Hsph1,Pik3cd,Atm,Swap70,Gbp2b,Tgtp1,Axl,Dck,Gbp9,Arl5c,Gk,Src,Hspa2,Fam20c,Slfn8,P2ry2,Igf1r,Irgq,Rap2c,Sgk3,Acvr1b,Hsd17b12,Sell,Rras2,Iigp1,Mx1,Atp2b4,Ptk2,Irgm1,Rac3,Dyrk2,Lpar1,Cenpe,Pikfyve,Oas3,Ksr1,Hcar2,Nod2,Nrp2,Ddx4,Abcb1a,Trip13,Chd9,Arl5b,Lyn,Prkce,Atp11a,Atp13a1,Sik3,Dnaja2,Plk2,Nlrc5,Katna1,Dgka,Lgals9,Tor3a,Rhof,Rab9,Nos2,Papss2,Ube2f,Slfn9,Pde5a,Flt1,Ltbp2,Smc5,Cd14,Tuba4a,Stk40,Agrn,Sphk1,Ddx58,Gmppb,Pim1,Pdk3,Rhoc,Rab10,Nlrp3,Map4k4,Samhd1,Scyl2,Ube2e1,Akt3,Hspa1b,Prkar2b,Acvr1,Oasl2,Ascc3,Irak2,Pf4,Ccl8,Ccl2,Ptch1,Mocs1,Ift22,Gbp3,Rhoh,Etnk1,Gbp2,Helz2,Nod1,Vrk2,Ass1,Ccl7,Tap1,Tap2,Acsl1,Hck,Tent2,Mcm9,Dhx58,Parp9,Nkiras1,Asns,Gfpt1,Gbp8,Arl4a,Jak2,Met,Rars,Map2k4,Hk1,Fgr,Pgs1,Prnp,Dync1h1,Rab20,Mcm6,Eif2ak2,Ifih1,Mov10,Pdgfrb,Acsl5,Prkx,Layn,Mapkapk2,Syk,Ripk3,Siglece,Kif3c,Rhou,Pim2,Kif9,Mark2,Gna15,Vcan,Gem,Sele,Pim3,Wars,Tent4a,Gch1,Grk3,Gclc,Trib1,Apaf1,Cmpk2,Gbp7,Rab21,Rhoq,Itpkc,Srxn1,Lipg,Rab32,Extl2,Actb,Oasl1,Ube2e2,Abcc1,Ep400,Pde4b |
| 1.400e-10 | -22.69 | external side of plasma membrane | cellular component | GO:0009897 | 430 | 67 | 20747 | 1409 |
H2-T24,Cx3cr1,Cd55,Cd86,Ldlr,H2-Aa,H2-Q6,Cd40,Siglece,Raet1e,Itga4,H2-T22,Klrk1,Fcgr2b,Ccr1,Cd200r4,Il2rg,Tnf,H2-Q7,Ccrl2,Itga5,Il13ra1,Cd80,H60b,Cd74,Slamf7,Itgav,Cxcl9,Ccr3,H2-Q4,Ly75,Thbs1,Xcr1,Fas,Tmem123,Icam1,Pdpn,Sdc1,Tnfrsf14,Cd34,Fcgr1,Ly6a,Vcam1,H2-M2,Antxr1,Csf3r,H2-T10,Sell,Ebi3,H2-Ab1,Cd69,Il12rb1,Adam19,Cxcl10,Gsr,P2ry12,Fcgr4,Cd83,Kdr,Spn,Tlr2,Il6,Itgal,Clec2d,Cd14,Cd274,Icosl |
| 1.401e-10 | -22.69 | GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_DN | 179 | 42 | 15632 | 1249 |
Brd2,Psmb8,Ifit1bl2,Rgl1,Ppp1r15a,St3gal5,Plscr1,Procr,Trim21,Tdrd7,Oasl1,Ell2,Fndc3a,Rnf19b,Ifi35,Nsmaf,Gpd2,Map3k8,Lpar1,Ak4,Phyh,Il1rn,Vrk2,Sp110,Ppp2r2a,N4bp1,Dusp1,Ifit1bl1,Gpr18,Ccdc86,Nat2,Ctsc,Dock10,4932438A13Rik,Irf2,Rars,Slc30a1,Isg15,Nr1h3,Adar,Gng11,Cd164 |
| 1.401e-10 | -22.69 | GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_UP | 179 | 42 | 15632 | 1249 |
Plekhf2,Trip10,Birc2,Phgdh,Sat1,Ctsc,Nat2,Ap3b1,Hdac1,Nck1,Tab2,Arl4a,Pfkfb3,Slc12a9,Cdyl,Rel,Irf8,Plekha2,Bcl9,Ociad1,Slc9a1,Akt3,Nfkbib,Psme2,Tifa,Stat4,Spint2,Tlr9,Casp7,Larp1,Tmod3,Smc5,Psmb6,Cox18,Il2rg,Cdc42ep4,Prkx,Dio2,Plekhn1,Cdkn1a,Nlgn2,Lrrc8c |
| 1.407e-10 | -22.68 | GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_DN | MSigDB lists | GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_DN | 186 | 43 | 15632 | 1249 |
Ifit1,Hvcn1,Slfn5,Irak3,Crlf3,Ddx58,Etv3,Calcrl,Usp18,Ubash3b,Rtp4,Il4ra,Pgs1,Nck1,Itga4,Rin2,Dock10,Samd9l,Abcb1a,Rgs14,Arid5a,Trim36,Ifit1bl1,Plekhn1,Clcf1,Tnfsf10,Prkx,Mob3b,Ifit3b,Ifi35,Rnf19a,Slamf9,Rasgrp1,Dgka,Oas2,Xaf1,Inpp5b,Akt3,Klf2,Ifit3,Osm,Slc4a7,Ifit1bl2 |
| 1.407e-10 | -22.68 | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 186 | 43 | 15632 | 1249 |
Nfkbiz,Egr1,Cdkn2d,Rhoh,Hif1a,Isg15,Pnpt1,Ifit1,Rab3ip,Daxx,Notch1,Mark2,Ezr,Plac8,Ehd1,Srm,Irgm2,Minpp1,Ppp2r5a,Dusp2,Rsad2,Acvrl1,St3gal1,Nr4a3,Znrf1,Ikbke,Ldlr,Plaur,Frmd6,Pdk3,Eif4g2,Map4k4,Cacybp,Atp6v1d,Irf7,Isg20,Cnn3,Ddit4,Ext1,Inpp5b,Ampd3,Rnf19a,Dgka |
| 1.407e-10 | -22.68 | GSE17721_PAM3CSK4_VS_CPG_24H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_24H_BMDC_DN | 186 | 43 | 15632 | 1249 |
Tor3a,Slc13a3,Nampt,Mov10,Gem,Psme2,Tlr1,Dck,Ripk2,Cd200,Dr1,Slfn9,Tmem219,Epsti1,Cmpk2,Trafd1,Pmepa1,Dync1h1,Ifit2,Spsb1,Gadd45b,Agrn,Ddhd1,Cyfip1,Cd40,Tor1aip2,Slfn8,Gbp9,Gbp4,Ccl2,Ccdc86,Mmp14,Mdm2,Acvr1,Pgs1,Nupr1,Cyth3,Psmb10,Mapkbp1,Gng11,1600014C10Rik,Tspo,Gbp2 |
| 1.442e-10 | -22.66 | positive regulation of peptidase activity | biological process | GO:0010952 | 176 | 38 | 20694 | 1406 |
Mmp25,Myc,Psme1,Sirt1,Malt1,Pmaip1,Nlrp3,Mefv,Antxr1,Uaca,Nlrc4,Stat1,Jak2,Nod1,Cycs,Lyn,Cav1,Fas,Apaf1,Ift57,Casp4,Tank,Stat3,Bcl2l11,Tnfsf10,Pml,Casp1,Casp8,S100a8,Syk,Psme2,Cflar,Tnfsf15,Fam162a,Mul1,Ripk2,Aim2,Tnf |
| 1.582e-10 | -22.57 | THUM_SYSTOLIC_HEART_FAILURE_UP | MSigDB lists | THUM_SYSTOLIC_HEART_FAILURE_UP | 362 | 66 | 15632 | 1249 |
H2-Ab1,Uchl1,Il2rg,Spire1,Vcam1,Cxcl1,Clic4,Plat,Thbs1,Tnfsf10,Htr2b,Nampt,Plk2,Phlda1,Pdlim7,Prdm1,Calcrl,Cd74,St3gal6,Cd14,Pdgfc,Casp1,Plekhf2,P2ry13,Eno1,Tank,Cp,Ccng2,Etnk1,Ptk2,Max,Oasl1,Stat1,Ms4a6d,Dnajb4,Lyn,Jak2,Actb,Notch2,Ccl4,Mier3,Clic5,Rnf14,Ltbp2,Irf8,Lap3,Cnn3,Zeb1,Rictor,Fas,St3gal3,Mapkapk2,Prnp,Sgcb,Slc16a1,Ppfibp1,Ezr,Cx3cr1,Gadd45b,Dhrs9,Msr1,Ctsc,Edn1,Pla2g4a,Sdc2,Vcan |
| 1.605e-10 | -22.55 | phosphorylation | biological process | GO:0016310 | 1024 | 124 | 20694 | 1406 |
Tlr9,Gk,Acvr1,St3gal1,Scyl2,Map2k4,Mecp2,Ptger4,Socs3,Inpp1,Map3k8,Stat5a,Socs1,Eif2ak2,Irak3,Myc,Pdgfrb,Zfp36,Morc3,Ptk2,Sgk3,Prag1,Prkx,Ccr3,Socs7,Dgkh,Cish,Ccng2,Papss2,Sgms2,Il15,Map4k4,Itpkc,Stat3,Hck,Dyrk2,Src,Ccne1,Cmpk2,Tlk2,Pdk3,Map2k1,Dgka,Lif,Pdgfb,Ak4,Nek6,Flt1,Mul1,Ripk2,Stk40,Ikbke,Irak2,Hk3,Il18,Akt3,Sphk1,Jak2,Cycs,Pgk1,Trib1,Il12rb1,Rictor,Pim1,Tyk2,Ripk3,Tlr2,Etnk1,Acvrl1,Myd88,Met,Eno2,Pml,Pikfyve,Ccl12,Ccnj,Pim2,Stat4,Syk,Kdr,Sik3,Plk3,Tnf,Mapkbp1,Mdfic,Mark2,Fgr,Vrk2,Map3k6,Igf1r,Pfkl,Ccl5,Hk1,Pik3cd,Plk2,Grk3,Dck,Tpi1,Bmp2,Atm,Ccnd2,Acvr1b,Ciita,Mmd,Ksr1,Saa3,Mlkl,Fam20c,Trib3,Axl,Mapkapk2,Il1b,Sla,Pim3,Tlr3,Hk2,Htr2b,Itgav,Ppm1l,Lyn,Osm,Ccnd1,Prkce,Cdk5r1 |
| 1.627e-10 | -22.54 | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN | 166 | 40 | 15632 | 1249 |
4930523C07Rik,Junb,Plek,Slc7a2,Il1rn,Tnfsf10,Nfil3,Ptges,Snn,Ifi35,Fam53c,Stat1,Trib1,Acsl1,Ddx4,Rab20,Stat3,Ppp2r5a,Slc15a3,Ogfrl1,Dhx58,Cxcl14,Cnn2,Dusp1,Abcc5,Fos,Csf3r,Dock4,Zyx,Pfkfb3,Fcgr1,Cdc42ep2,Slc48a1,Gbp2,Tnfaip3,Atf3,Irf2,Psme1,Pml,Icam1 |
| 1.670e-10 | -22.51 | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_UP | MSigDB lists | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_UP | 173 | 41 | 15632 | 1249 |
Stat1,Ptgir,Etnk1,Ms4a6d,Irf1,Nfkb2,Sh3bgrl2,Ppfibp2,Ankib1,Jarid2,Col11a2,Cacybp,Rel,Psme2,Nmi,Cnn3,Il12rb1,Ifih1,Fabp3,Gbp3,Usp18,Icam1,Tnfrsf8,Relb,Gbp2,Ifit1,Bcl2l11,Sqstm1,Cnn2,Nr4a1,Hivep2,Gadd45b,Cd40,Ptpn2,Psmb9,Egr2,Ikzf1,Irgm2,Irf4,Abcb1a,Cox17 |
| 1.679e-10 | -22.51 | GO_REGULATION_OF_PROTEIN_LOCALIZATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_LOCALIZATION | 859 | 122 | 15632 | 1249 |
Bambi,Hcar2,Vegfc,Zc3h12a,Ptger4,Il12b,Clec5a,Ptgs2,Tlr1,Csf3,G3bp2,Txn1,Mdfic,Lif,Pml,Nfkbil1,Trim12c,Socs1,Fgr,Sphk1,Hif1a,Ddx58,Il1a,Rab9,Rhoq,Tbc1d1,Lztfl1,Mdm2,Ifnar1,Casp1,Lrp4,Hsph1,Src,Slc2a1,Cd40,Itpr1,Swap70,Hcls1,Cacna1d,Nlgn2,Pfkl,Stard7,Dyrk2,Tnfsf4,Tlr2,Rasgrp1,Sirt1,Rnf31,Rabgef1,Clec4n,Ptch1,Il10,Tnfsf14,Prdx1,Angpt1,Tnfrsf14,Tlr6,Il4ra,Nlrp3,Prnp,Prkce,Ppp2r5a,Il6,Nod2,Ccl12,Bcl2l11,Nfkbia,Ezr,Psmd10,Sec24a,Il1b,Keap1,Htr2b,Tlr3,Il18,Fzd1,Mmp13,Gja1,Ccl5,H2-Eb1,Cd274,Fzd5,Cd14,Plagl2,Cd38,Plk3,Parp10,Aim2,Rab11fip1,Micall2,Gpr68,Rsad2,Nfkbie,Rbpms,Tnf,Rhbdf2,Serp1,Traf2,Jak2,Cdkn1a,Dnajb2,Tlr9,Lyn,Nfkbib,Slc9a1,Stx6,Rhou,Mmd,Casp8,Nos2,Pid1,Clec4e,Slc16a1,Cd34,Pim3,Cdk5r1,Cx3cl1,Nr1h3,Irs2,Syk,Gsdmd,Dnaja1 |
| 1.684e-10 | -22.50 | GO_REGULATION_OF_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CATABOLIC_PROCESS | 692 | 104 | 15632 | 1249 |
Pikfyve,Cdk5r1,Irs2,Ifi214,Usp25,Zc3hav1,Ifi207,Tspo,Rnf114,Sqstm1,Bnip3,Ctsc,Rab20,Trib1,Odc1,Ifi204,Pim2,Dram1,Ptk2,Mtdh,Dnajb2,Ldlr,Polr2g,Mndal,Nos2,Cav1,Rnf14,Tnfrsf1b,Atm,Zfp36,Psme2,Ifi211,Trim21,Psmb10,Tab2,Rnf139,Plk3,Tnfaip3,Irak3,Apaf1,Ifi209,Tnf,Tlk2,Stat3,Trib3,Ripk2,Psmb6,Hp,Keap1,Il1b,Htr2b,Atp6v1d,Fzd5,Gja1,Ppp2r3a,Sh3bp4,Ddit4,Trim13,Atp2b4,Chmp4b,Pde3b,Gclc,Htr2a,Pnpt1,Tiparp,Psmd10,Ezr,Prkce,Adrb2,Mefv,Kdr,Il10,Psmb8,Ankib1,Ifi203,Met,Rnf19a,Sirt1,Hif1a,Kdm4a,Pml,Psme1,Ube2e1,Nod1,Ifi205,Itpr1,Timp1,Psmb9,Casp1,N4bp1,Dusp1,Ifi213,Psma6,Mdm2,Casp3,Zc3h12a,Uchl1,Smc5,Rnf19b,Larp1,Hcar2,Plk2,Ifi208,Btg2 |
| 1.689e-10 | -22.50 | GSE2585_CTEC_VS_THYMIC_DC_DN | MSigDB lists | GSE2585_CTEC_VS_THYMIC_DC_DN | 187 | 43 | 15632 | 1249 |
Cxcl10,Pcdh7,Plat,Irak2,Ptges,Samsn1,Osm,Sap30,Tlr1,Nfkbid,Stoml1,Hap1,Maff,Pml,Rnd1,Nod1,Bmp2,1600014C10Rik,Slc25a37,Plod3,Ctu1,Cp,Tapbp,Sema4c,Adam19,Pfkl,Gfi1,Pmepa1,Nfkb1,Gbp7,Nfkbib,Slamf9,Rasgrp1,Tmem176a,Mapkapk2,Egr1,Arrdc4,P2ry14,Enpp4,Olr1,Cx3cr1,Irgm2,Mllt6 |
| 1.689e-10 | -22.50 | GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_DN | MSigDB lists | GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_DN | 187 | 43 | 15632 | 1249 |
1110038F14Rik,Gbp4,Gbp9,Psmb9,Ifit2,Crim1,Ifit1,Rab3ip,Gbp2,Ahsa1,Usp18,Psme1,Parp12,Gch1,Epsti1,Cmpk2,Ikbke,Slfn9,Larp1,Oas1g,Parp9,Slfn8,Parp14,Gramd1a,Rnf114,Bcl2l11,Agrn,Rtp4,Gmppb,Ddx60,Oas1a,Usp12,Zeb1,Ifit3,Psmb8,Wdr43,Znrf1,Tnip1,Rnf145,Irf1,Ifit3b,Ifi35,Stat1 |
| 1.689e-10 | -22.50 | GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_DN | MSigDB lists | GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_DN | 187 | 43 | 15632 | 1249 |
Rhoc,Mdfic,Pilrb2,Nod1,Slamf7,Gpc1,Rab19,Gbp3,Traf1,St3gal6,Mcoln2,Tpi1,Errfi1,Arhgap26,B3gnt5,Bcl2a1d,Fcgr2b,Carhsp1,Ttc39c,Slc2a1,Plac8,Cst7,Apobec3,Bcl2a1b,Epsti1,Pkp4,Nfil3,Bcl2a1a,Pilrb1,Ralgds,Rcn1,Endod1,Ptger4,Kif5c,Stat4,Rap1gap2,Stx11,Il18rap,Cysltr2,Plscr1,Hopx,Igsf8,Txn1 |
| 1.701e-10 | -22.49 | GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | MSigDB lists | GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 471 | 79 | 15632 | 1249 |
Ptafr,Nr4a3,Trib3,Ptgs2,Ripk2,Gng4,Tlr3,Htr2b,Il1b,Gng12,Atp6v1d,Ppp1r15a,Klf2,Ccl5,Ifit1bl2,Pde4b,Nampt,Fzd1,Sh3bp4,Rapgef2,Rab10,Agtrap,Socs1,Hif1a,Icam1,Pdgfc,Gnb4,Nod1,Traf2,P2ry12,Stat5a,Tnf,Klf6,Src,Mdm2,Errfi1,Rhoq,Stat3,Lyn,Cpeb4,Tnfsf4,Ptk2,Max,Prkar2b,Socs7,Igf1r,Jak2,Gfpt1,P2ry2,Casp4,Cav1,Gna15,Nfkb1,Slc9a1,Zeb1,Mul1,Irs2,Cdk5r1,Kat2b,Phip,Egr1,Fas,Zc3hav1,Atp2b4,Adar,Gng11,Pde3b,Plau,Ptpn2,Ass1,Agrn,Ccl12,Ezr,Ifit1bl1,Klf3,Nr4a1,Ifnb1,Nod2,Edn1 |
| 1.768e-10 | -22.46 | Signaling by Interleukins | REACTOME pathways | R-MMU-449147 | 388 | 73 | 8608 | 757 |
Irs2,Ppp2r5a,Tab2,Socs3,Pdgfb,Kitl,Il1rn,Jak2,Map2k1,Map3k8,Pdgfrb,Il1a,Ksr1,Il2rg,Psme2,Csf3,Psma6,Stat3,Ptk2,Met,Psmb8,Ripk2,Osm,Psmb6,Dusp6,Psme1,Dusp5,Irak2,Nod1,Rasgrp1,Stat1,Rapgef2,Ebi3,Irak3,Casp1,Il6,Src,Angpt1,Psme2b,Lgals9,Il12rb1,Nfkb1,Spred1,Il18,Nod2,Il15,Lif,Ppp2r1b,Syk,Il1b,Il18bp,Peli1,Tyk2,Casp3,Myd88,Il10,Psmd10,Psmb10,Csf3r,Clcf1,Ikbkg,Il27,Il13ra1,Il15ra,Il12b,Il4ra,Crkl,Nfkb2,Psmb9,Sqstm1,Pik3cd,Il18rap,Stat5a |
| 1.791e-10 | -22.44 | MODULE_456 | MSigDB lists | MODULE_456 | 102 | 30 | 15632 | 1249 |
Ifit1bl2,Samsn1,Tlr1,Mmd,Stat4,Stx11,Ptger4,Dusp5,Slc43a3,Trib3,Asb13,Nr4a3,Nfkb2,Prkar2b,Cdkn1a,Il1b,Tnf,Ifit1bl1,Nfkbia,Swap70,Bcl6,Oas3,Il6,Sele,Hif1a,Traf1,Cd83,Ripk3,Cd38,Tnfaip3 |
| 1.965e-10 | -22.35 | GNF2_CARD15 | MSigDB lists | GNF2_CARD15 | 63 | 23 | 15632 | 1249 |
Pilra,Cd14,Fcgr1,Hk3,Hck,Dusp1,Casp1,Fos,Cd302,Igsf6,Vcan,Nod2,Fgl2,Ms4a6d,Tlr2,Fpr1,Tnfaip2,Ccr1,Dusp6,Tnfrsf1b,Cd86,Bst1,Stx11 |
| 1.968e-10 | -22.35 | SMID_BREAST_CANCER_NORMAL_LIKE_UP | MSigDB lists | SMID_BREAST_CANCER_NORMAL_LIKE_UP | 430 | 74 | 15632 | 1249 |
Rbms1,Ppp2r1b,C3,Ms4a6d,Ifi204,Lyn,Pik3cd,Ifi211,Zeb1,Isg20,Ifi203,Cd69,Kctd12,Met,Birc3,Tnfrsf1b,Itgal,Irf8,Cav1,Gem,Mndal,Ciita,F10,Zbp1,Gng11,Ifi207,Col18a1,P2ry14,Nlrp3,Ifi214,Spry2,Ctsc,Stap1,Il6,Dtnb,Aoah,Hivep2,Plac8,Ccl12,Gpr18,Cxcl1,Vcam1,Plcl2,Sp110,H2-Ab1,Ptger4,Il2rg,Ifi208,Ccl5,Flrt2,Lcp2,Sla,Cd38,Ch25h,Hhex,Itga4,Cd180,Cd74,Sell,Slco3a1,Ly75,Sele,Dock10,C1ra,Acvrl1,Ifi213,Sp140,Casp1,Arid5a,Ifi205,Tcf4,Cd40,Cd302,Ifi209 |
| 1.972e-10 | -22.35 | regulation of T cell proliferation | biological process | GO:0042129 | 170 | 37 | 20694 | 1406 |
Il27,Spn,Nck1,Icosl,Irf1,Tnfsf9,Prnp,Peli1,H2-Ab1,Sdc4,Tnfsf4,Cd86,Cd80,H2-Aa,Syk,Il6,Arg2,Stat5a,Ripk2,Slfn1,Pde5a,Il18,Tnfrsf1b,Itgal,Lgals9,Ccdc88b,Cd274,Il1b,Il12b,Vcam1,Casp3,Tarm1,Il12rb1,Tnfrsf14,Il15,Ripk3,Ccl5 |
| 1.976e-10 | -22.34 | REACTOME_ADAPTIVE_IMMUNE_SYSTEM | MSigDB lists | REACTOME_ADAPTIVE_IMMUNE_SYSTEM | 481 | 80 | 15632 | 1249 |
H2-Eb1,Cd274,Lcp2,Cd86,Tap2,Ube2l6,Icosl,H2-Aa,Vasp,Uba7,Ripk2,Psmb6,Trib3,Kif3c,Map3k8,Vcam1,Keap1,Sec24b,Dync1h1,Src,H2-Q6,Psmb9,Cd40,Nfkbie,Mdm2,Psma6,Malt1,Psme1,H2-Q7,Ube2e1,Icam1,Tab2,Cd74,Sell,Socs1,Psmb10,Dtx3l,Rnf34,Ube2f,Psmb8,Lnpep,Ikbkg,Itgal,Rel,Ubr4,Trim21,Akt3,Nfkbib,Psme2,Ube2e2,Rictor,Rasgrp1,Rap1gap2,C3,Socs3,Pik3cd,Lyn,Asb13,Ppp2r1b,Cdkn1a,Nr4a1,Spsb1,Nfkbia,Trim36,H2-Q4,Syk,Itgav,Psmd10,Fcgr2b,Ctsc,Ppp2r5a,Phlpp1,Evl,Nck1,Cd34,Fbxo4,Cd80,Fcgr1,Tnfrsf14,Tap1 |
| 1.992e-10 | -22.34 | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | 195 | 44 | 15632 | 1249 |
Mndal,Rhou,Ifi203,Akt3,Ifi211,Tifa,Ifi204,Trib1,Abcc1,Vrk2,Cd82,Adam19,Ezr,Spsb1,Nod2,Ctsc,Pttg1,Ifi214,Fas,Ifi207,Atp2b4,Ahr,Rapgef2,Sap30,Piezo1,Ifi208,Arid5b,Rnf19b,Dusp5,Osbpl3,Cldnd1,Ifi209,Ifi205,Dpy19l1,Ifi213,Gpr68,Rab11fip1,Dennd1b,Cd74,Rnf135,Prdm1,Rgs3,Ncoa7,Batf |
| 2.019e-10 | -22.32 | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN | MSigDB lists | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN | 174 | 41 | 15632 | 1249 |
Keap1,Vrk2,Jak2,Ptgs2,Oas1g,Stat1,Ifi35,Ptprj,Oas2,Rap1gap2,Xaf1,Parp12,Oas1a,Psme2,Plscr1,Ube2l6,Myo1b,4930523C07Rik,Plek,Gbp2,Rbl1,Ppfibp1,Cd38,Slamf7,Batf,Trim12c,Atp11a,Usp18,Ddx60,Aim2,Rsad2,Stap1,Ifi44,Pla2g4a,Oas3,Trip10,Homer1,Ifnar1,Apobec3,Usp53,Eif2ak2 |
| 2.024e-10 | -22.32 | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_UP | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_UP | 188 | 43 | 15632 | 1249 |
Samsn1,Cdyl,Vasp,Pdgfb,Pdlim7,Piezo1,Rcan1,Il2rg,Rtn1,Ldha,Acp2,Pilrb1,Inpp1,Bcl6,Lipe,Stat3,Spata13,Rab19,Slc39a13,Nupr1,Rgs3,Itgal,Tnfrsf1b,Slamf9,Socs3,Trem1,Agpat4,Lrrc8c,Ppp2r1b,Hmga1,Ets2,Rhof,Ezr,Spn,Ifrd1,Gpr35,Ccnd2,Evl,Spred1,Pilra,Pilrb2,Col4a2,Lpcat2 |
| 2.024e-10 | -22.32 | GSE7852_LN_VS_FAT_TCONV_DN | MSigDB lists | GSE7852_LN_VS_FAT_TCONV_DN | 188 | 43 | 15632 | 1249 |
Rap1gap2,Kctd12,Tnfsf14,Il10,Nfil3,Cdkn1a,Agpat4,Mmp9,Sema4c,Ier3,Odc1,Abcb1a,Bcl2a1b,Sod2,Hivep2,Nr4a1,Atp2b4,Nfkbiz,Atf3,Trim13,Sap30,Cxcl2,Myadm,Plek,Txn1,Fosb,Ppp1r15a,Hopx,Samsn1,Bcl2a1a,Epsti1,Dusp5,Rnf19b,Phf6,Pnp2,Bcl2a1d,Arhgap26,Casp1,Plekhf2,Dpy19l1,Ttc39c,Mdfic,Prdm1 |
| 2.024e-10 | -22.32 | GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_DN | 188 | 43 | 15632 | 1249 |
Prdm1,Pgs1,St3gal6,Slco3a1,Prnp,Usp18,Pttg1,Batf,Myd88,Il15,Klf7,Plekha5,Slc7a11,Plac8,Stat5a,Ehd1,Jun,Il6,Gadd45g,Ldha,Socs3,Tmod3,Tnfsf4,Rnf19b,Map3k8,Acsl1,Serpinb9,St7,Adrb2,Cacnb3,Pim1,Cldnd1,Tax1bp1,Tnfsf10,Igf2bp2,Gja1,Ahrr,Jarid2,Casp4,Gem,Hopx,Ksr1,Adora2a |
| 2.025e-10 | -22.32 | membrane region | cellular component | GO:0098589 | 377 | 61 | 20747 | 1409 |
Lrp8,Sele,Adrb2,Lipe,Gja1,Asah2,Casp3,Pikfyve,Tnf,Fcgr2b,Grk3,Plscr1,Tlr6,Traf2,Sdc4,Lyn,Ptch1,Lrp4,Casp8,Actb,Gpc1,Tlr1,Kcna3,Ldlr,Hck,Ppp2r1b,Cd55,Pgk1,Cflar,Hmox1,Rhoq,Cd14,Prkar2b,Tlr2,Kdr,Hspa1a,P2ry12,Src,Angpt1,Lcp2,Prnp,Ezr,Birc2,Myadm,Cav1,Eno1,Slc9a1,Igf1r,Ptgs2,Fcgr1,Slc2a1,Birc3,Jak2,Tnfrsf1b,Eno2,Pdpn,Icam1,Itpr1,Hk1,Ednrb,Fas |
| 2.034e-10 | -22.32 | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_UP | 181 | 42 | 15632 | 1249 |
Timp1,Gypc,Rnf114,Parp8,Mdm2,Kdm5b,Il4i1,Sat1,Slfn8,Ifih1,Rnf135,Mthfr,Prpf38a,Gbp2,Pnpt1,Cd80,Zbp1,Ciita,F10,Rnf34,Casp4,Ptch1,Cd86,Samsn1,Ifit3,Eno2,Slc12a9,Dgka,Car13,Psme2,Cdc42ep4,Asb13,Nr4a3,Ifit3b,Pim1,Ldha,Parp3,Mtmr14,Ptges,Slfn9,Rgs1,Il1rn |
| 2.034e-10 | -22.32 | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_DN | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_DN | 181 | 42 | 15632 | 1249 |
Frmd4a,Rcsd1,Mefv,Tgfbi,Epsti1,Adam19,Ikbke,Fam102b,Igsf8,Pik3r6,Gbp7,Tnfsf14,4930523C07Rik,Tor3a,Tyk2,Rhou,Slc25a12,Hivep3,Slpi,Sell,Papss2,Nmral1,Mthfr,Fas,Slfn5,Notch1,F10,Kif9,Tmem184b,Serp1,Cd302,Itpr1,Ttc39c,Arid5a,Agrn,Dpy19l1,Ift57,Glipr2,Lztfl1,Arhgap26,Pnp2,Ctsc |
| 2.034e-10 | -22.32 | GSE43955_10H_VS_60H_ACT_CD4_TCELL_DN | MSigDB lists | GSE43955_10H_VS_60H_ACT_CD4_TCELL_DN | 181 | 42 | 15632 | 1249 |
Myo10,Traf5,Slc16a1,Pgm1,Pttg1,Irs2,Tmem176b,Cdkn2d,Mcoln2,Glipr2,Errfi1,Prdx5,Irf4,Fcgr2b,Dusp8,Zyx,Spsb1,Klf3,Dusp1,N4bp1,Bcl2l11,Igf1r,Cflar,Kdr,Plat,Serpinb2,Tgfbi,Rcan1,Adora2b,Il12b,Degs2,Hk2,Ddit4,Phlda1,Flnb,Il10,Casp4,Fosb,Tor3a,Junb,Gja1,Hk1 |
| 2.082e-10 | -22.29 | positive regulation of cellular component organization | biological process | GO:0051130 | 1219 | 141 | 20694 | 1406 |
Mecp2,Lnpk,Cenpe,Kif3c,Cenpj,Fchsd2,Ehd1,Pdpn,Aim2,Fcgr1,Adrb2,Evl,Cdc42ep4,Rab21,Plaur,Scyl2,D16Ertd472e,Stap1,Edn1,Triobp,Rhoq,Resf1,Serpine1,Carmil1,Flrt2,Nsd3,Lrp8,Fas,Ccl8,Pdgfrb,Gda,Phldb1,Rhoc,Rac3,Scn1b,Lif,Cxcl9,Pdgfb,Lrp4,Lpar1,Mul1,Irgm2,Smc5,Piezo1,Map4k4,Nr3c1,Csf3,Hck,Bcl2l11,Src,Cdc42ep2,Lcn2,Hap1,Jarid2,Ptprj,Eif4g2,Map2k1,Sphk1,Crkl,Flrt3,Tlr6,Rictor,Mpp7,Optn,Swap70,Sele,Scarf1,Syk,Kdr,Fam162a,P2ry12,Fzd1,Cx3cl1,Tnf,P2ry2,Il1a,Daxx,Nck1,Irgm1,Angpt1,Met,Tnfsf10,Ikzf1,Pml,Pla2g4a,Arid5a,Sdc4,Nlgn2,Igf1r,Nox1,Phip,Wars,Dync1h1,Tmem67,Kat2b,Jdp2,Rgcc,Icam1,Fscn1,Bcl6,Bnip3,Gdf15,Ppp1r15a,Cd14,C3,Mark2,Agrn,Atm,Il6,Cyfip1,G3bp2,Hif1a,Vasp,Cflar,Rapgef2,Prdm9,Whamm,Plek,Fbxo4,Ddhd1,Adgrl2,Sema4a,Dbnl,Hk2,Itpr1,Lyn,Cav1,Il4ra,Myadm,Tnfsf14,Ahr,Sdc1,Spire1,Prkce,Palld,Mmp9,Sirt1,Axl,Pmaip1,Gpsm2,Il1b |
| 2.082e-10 | -22.29 | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | MSigDB lists | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | 147 | 37 | 15632 | 1249 |
Dse,Nod2,Kdm5b,Mecp2,Dusp4,Sphk1,Marcksl1,Egr1,Rgs3,Irak3,Hck,Pfkfb3,Plau,Sla,Cd14,Gna15,Marco,Adap2,P2ry2,Ccr1,Tnfrsf1b,Bst1,Maff,Slc7a5,Pdlim7,Tgfbi,Mafg,Ier3,Acsl1,Fpr1,Tlr2,Hmox1,Cdkn1a,Ptges,Thbs1,Serpinb2,Rgs1 |
| 2.104e-10 | -22.28 | GO_CELLULAR_RESPONSE_TO_STRESS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_STRESS | 1422 | 179 | 15632 | 1249 |
Kat2b,Nek6,Cdkn2d,Fas,Tspo,Cited2,Hmga1,Parp9,Bnip3,Map2k4,Ifi204,Cpeb4,Dnajb2,Fam162a,Gfpt1,Cav1,Tnfrsf1b,Egln3,Il18rap,Ifi211,Tab2,Plk3,Stau1,Apaf1,Ube2f,Batf,Rnf34,Ifi209,Prdx5,Slc39a4,Map3k8,Adora2b,Ripk2,Parp3,Hmox1,Ikbke,Irf7,Map2k1,Mmp13,Ddit4,Pttg1,Plagl1,Egr1,Atf3,Tnks1bp1,Pnpt1,Fos,Bcl2l11,Map3k6,Nod2,Prkce,Edn1,Adrb2,Dyrk2,Nox1,Trem1,Rims3,Casp4,Mcm9,Ifi203,Casp2,Sirt1,Isg15,Il1a,Hif1a,Stat2,Mdfic,Relb,Notch1,Hspa1a,Slc2a1,Rbbp8,Itpr1,Rgs14,Src,Ccnd1,Mdm2,Casp3,Cxcl10,Zc3h12a,Ptger4,Tcea1,Thbs1,Ascc3,Klf2,Plk2,Ube2l6,Wdr59,Mul1,Ifi214,Nck1,Ifi207,Dnaja1,Syk,Ass1,Sod2,Bcl2a1b,Sqstm1,Eif2ak2,Cnot4,Lyn,Rcsd1,Trib1,Max,Cdkn1a,Vrk2,Jak2,Polr2g,Plod2,Cenpj,Mndal,Ppp1r15b,Ikbkg,Nfkb1,Atm,Slc9a1,Upp1,Rnf139,Nupr1,Tnfaip3,Etv5,Serp1,Bcl6,Traf2,Klf6,Tnf,Errfi1,Tlk2,Tnc,Trib3,Crkl,Irak2,Asns,Ppp1r15a,Ccl5,Fcgr4,Vasn,Eya4,Trim13,Mapkapk2,Hinfp,Plau,Prdx1,Jun,Ccl12,Nfkbia,Nqo1,Il18bp,Myc,Il6,Itpkc,Asf1a,Tmem67,Pdk3,Leng9,Ube2e2,Trip13,Timeless,Dtx3l,Sphk1,Icam1,Pml,Mcm10,Daxx,Nod1,Ifi205,Ifi213,Bcl2a1d,Dbnl,Top3a,Ptgs2,Smc5,Kdm6b,Tfec,Bcl2a1a,Uba7,Hk2,Ifi208,Btg2 |
| 2.198e-10 | -22.24 | GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_DEVELOPMENT | 1576 | 194 | 15632 | 1249 |
Gfi1,Nlgn2,Clcf1,Adrb2,Stat1,Rasgrp1,Jag1,Sirt1,Cysltr2,Ptch1,Psmb8,Nlrp3,Egr1,4932438A13Rik,Edn1,Irf4,Fos,Psmd10,Agrn,Flrt3,Flt1,Sec24b,Pf4,Zhx2,Vegfc,Thbs1,Bambi,Cxcl10,Zc3h12a,Ptger4,Csf3,Pdgfb,Sipa1l1,Plk2,Daam1,Notch1,Cd83,Isg15,Hif1a,Il1a,Lif,Hlx,Psma6,Kdm5b,Ccnd1,Pnp2,Cd40,P2ry12,Rgs14,Ust,Lpar1,C3,Rac3,Mtdh,Egr3,Rap1gap2,Tmem176a,Spen,Zeb1,Cav1,Ednrb,Gpc1,Cd80,Tspo,Col4a2,Il27,Cd34,Cx3cl1,Znrf3,Cdk5r1,Kat2b,Ubash3b,Bcor,Fas,Scarf1,S1pr2,Mmp14,Pla2g4a,Cited2,Ptpn2,Keap1,Il1b,Kitl,Gcnt2,Hmox1,Psmb6,Ripk2,Ppp2r3a,Serpine1,Map2k1,Pdgfrb,Irf7,Fzd5,Hopx,Gja1,Ccr1,Irak3,Pbx1,Sav1,Psmb10,Prdm1,Mecp2,Glipr2,Stat3,Tcf4,Csf3r,Phldb1,Hcls1,Kdr,Fam20c,Mafg,Sema4a,Irf1,Acvr1b,Tnfsf4,P2ry2,Il10,Mark2,Pde3b,Plau,Il4ra,Lrp8,Sdc2,Myc,Il6,Ccr3,Jun,Ccl12,Cx3cr1,Nfkbia,Prkx,Il1rn,Il12b,Ptgs2,Maff,Hap1,Wars,Nfkbid,Scn1b,Pik3r6,Cd86,Bmp2,Sphk1,Pml,Hhex,Psme1,Acvrl1,Acvr1,Psmb9,Timp1,Lrp4,Axl,Lyn,Trib1,Itga5,Sema4c,Ptk2,Mmd,Psme2,Csf1,Casp8,Sema3c,Il15,Mul1,Tmem176b,Ifnb1,Ifrd1,Phlpp1,Ap3b1,Stap1,Katna1,Syk,Eif2ak2,Tlr3,Fzd1,Rapgef2,Il12rb1,Inhba,Vasn,Ppp1r15a,Flrt2,Ccl5,Myadm,Dusp6,Tnfaip3,Etv5,Tulp3,Cd74,Nupr1,Gpr68,Errfi1,Rab21,Bcl6,Tnf |
| 2.312e-10 | -22.19 | regulation of production of molecular mediator of immune response | biological process | GO:0002700 | 148 | 34 | 20694 | 1406 |
Tlr3,Cd40,Ddx58,Clcf1,Nr4a3,Hk1,Tlr2,Hmox1,Tnfrsf14,Tnfaip3,Il4ra,Nod2,Ifnb1,Tnfrsf1b,Malt1,Fzd5,Il18,Bcl6,Irak3,Il1b,Cgas,Nlrp3,Parp3,Cd74,Traf2,Il6,Tnf,Rsad2,Angpt1,Tlr9,Arid5a,Tnfsf4,Fcgr2b,Il10 |
| 2.321e-10 | -22.18 | GESERICK_TERT_TARGETS_DN | MSigDB lists | GESERICK_TERT_TARGETS_DN | 20 | 13 | 15632 | 1249 |
Junb,Nr4a1,Gadd45b,Dusp6,Fosb,Btg2,Egr2,Zfp36,Errfi1,Gadd45g,Nfkbiz,Ier3,Nfil3 |
| 2.321e-10 | -22.18 | TIAN_TNF_SIGNALING_NOT_VIA_NFKB | MSigDB lists | TIAN_TNF_SIGNALING_NOT_VIA_NFKB | 20 | 13 | 15632 | 1249 |
Maff,Dusp2,Ext1,Fosb,Tiparp,Jun,Ppp1r15a,Klf6,Nr4a1,Junb,Ptges,Ier3,Egr1 |
| 2.354e-10 | -22.17 | cell activation involved in immune response | biological process | GO:0002263 | 171 | 37 | 20694 | 1406 |
Clec4e,Icam1,Nr4a3,Clec4d,Prkce,Lyn,Tnfaip3,Notch2,Relb,Ifnb1,Itgal,Ifna1,Swap70,Irf4,Fgl2,Dnase1l3,Gadd45g,Plcl2,Il12b,Cd180,Ifna5,Ifna2,Il6,Syk,Ptger4,Ifna4,Batf,Stat3,Icosl,Milr1,Ifna6,Spn,Rasgrp1,Stx11,Dock10,Cx3cr1,Sema4a |
| 2.381e-10 | -22.16 | positive regulation of organelle organization | biological process | GO:0010638 | 583 | 82 | 20694 | 1406 |
Mecp2,Kdr,Lnpk,Cenpe,Cenpj,Fchsd2,Fam162a,Tnf,Cx3cl1,Daxx,Il1a,Nck1,Evl,Adrb2,Irgm1,Met,Cdc42ep4,Tnfsf10,Pml,Plaur,Pla2g4a,Arid5a,Sdc4,Igf1r,Edn1,Stap1,Phip,Tmem67,Dync1h1,Resf1,Carmil1,Jdp2,Kat2b,Nsd3,Icam1,Rgcc,Fas,Fscn1,Bcl6,Bnip3,Pdgfrb,Gda,Rac3,Rhoc,Cyfip1,Atm,Pdgfb,Lif,G3bp2,Hif1a,Lpar1,Mul1,Vasp,Irgm2,Smc5,Prdm9,Whamm,Fbxo4,Src,Cdc42ep2,Plek,Csf3,Hck,Bcl2l11,Hap1,Ddhd1,Jarid2,Sphk1,Hk2,Cav1,Rictor,Sdc1,Prkce,Spire1,Optn,Swap70,Mmp9,Sirt1,Palld,Gpsm2,Pmaip1,Il1b |
| 2.399e-10 | -22.15 | GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN | MSigDB lists | GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN | 168 | 40 | 15632 | 1249 |
Rsad2,Dhx58,Ifi44,Sat1,Oas3,Agrn,Plac8,Eif2ak2,Relb,Ncoa7,Ube2f,Zbp1,Myd88,Isg15,Sphk1,Usp18,Fas,Ddx60,Xaf1,Parp12,Oas2,Plscr1,Alas1,Irf7,Mov10,Il10,Mthfd1l,S100a8,Cmpk2,Epsti1,Ldlr,Bambi,Arf4,Mthfd2,Tlr2,Fndc3a,Oasl1,Ldha,Herc6,Ifi35 |
| 2.444e-10 | -22.13 | GSE17721_0.5H_VS_24H_LPS_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_24H_LPS_BMDC_DN | 182 | 42 | 15632 | 1249 |
Stxbp3,Rab10,Ube2l6,G3bp2,Ccl5,Snx10,Asns,Sema3c,Slfn4,Marco,Irf8,Kdr,Slfn9,Mitd1,Slfn3,Arf4,Gtpbp2,Xcr1,Vegfc,Etnk1,St3gal1,Mafg,Chic2,Tgfbi,Grina,Slc39a4,Irgm2,Slfn8,Pcx,Cpd,Gypc,P4ha2,Slc28a2,Tap1,Mdfic,Nupr1,Cdkn2d,Itga4,Gbe1,Fabp3,Gbp3,Nkiras1 |
| 2.444e-10 | -22.13 | positive regulation of secretion by cell | biological process | GO:1903532 | 474 | 71 | 20694 | 1406 |
Sphk1,Jak2,Gja1,Htr2b,Ifnar1,Tnfrsf14,Osm,Il4ra,Sdc1,Clec4e,Ddx58,Prkce,Tlr2,Clcf1,Frmd4a,Clec4n,Sirt1,Lgals9,Il1b,Nlrp3,Cd274,Il6,Lif,Ptafr,Hif1a,Ripk2,Tnfsf15,Casp4,Gpr68,Cd38,Nr3c1,Cd34,Clec5a,Src,Rab9,Adora2b,Casp1,Sec24a,Nlgn2,Fgr,Ifih1,Edn1,Irs2,Nod2,Hcar2,Hk1,Rgcc,Fzd5,Gsdmd,Cd14,Kmo,Tlr1,Vegfc,Ptger4,Syk,Mmp13,Stxbp1,Cacna1d,Tnf,Aim2,Adora2a,Ccl3,Il1a,Serp1,Ezr,Il10,Arid5a,Rasgrp1,Glrx,Sdc4,Tnfsf4 |
| 2.486e-10 | -22.12 | chemokine receptor binding | molecular function | GO:0042379 | 66 | 22 | 20217 | 1400 |
Cx3cl1,Cxcl2,Pf4,Ccl4,Cxcl9,Ccl12,Cxcl14,Nes,Ccl5,Ccrl2,Cxcl3,Ccl22,Cxcl10,Ccl9,Ccl3,Ccl7,Ccl2,Cxcl1,Ccl8,Stat1,Stat3,Cxcl11 |
| 2.512e-10 | -22.10 | MODULE_118 | MSigDB lists | MODULE_118 | 374 | 67 | 15632 | 1249 |
Rai14,Myc,Ctsc,Nqo1,Bcl2a1b,Ccl12,Slc7a11,Ifit1bl1,Zyx,Fos,Rnd3,Plau,Tpx2,Ccnd2,Pttg1,Trip13,Ppp4r2,Cnn3,Casp2,Ikbkg,Eno2,Psmb8,S100a8,Plod2,Cav1,Ldlr,Ccl4,Adam19,Rgs1,Cdkn1a,Mmp9,Rac3,Ier3,Pnp2,Tnc,D1Ertd622e,Bcl2a1d,Slc16a3,Cst7,Tnf,Slc2a1,Sla,Myo10,Hck,Crim1,Mthfr,Isg15,H2-Aa,Slc7a5,Ddit4,Maff,Hap1,Ccl5,Gdf15,Gja1,Dusp6,Pde4b,Ifit1bl2,Junb,Serpine1,Plat,Thbs1,Bcl2a1a,Gng12,Il2rg,Mcm6,Lox |
| 2.593e-10 | -22.07 | Hepatitis C | KEGG pathways | mmu05160 | 134 | 37 | 7931 | 713 |
Oas1a,Stat2,Ifna4,Irf1,Ikbkg,Ifna6,Ppp2r1b,Cdkn1a,Socs3,Eif2ak2,Ifnb1,Oas1b,Nr1h3,Ifna5,Irf7,Ifit1bl1,Nfkbia,Stat3,Oas2,Oas3,Tnf,Ifnar1,Ifit1,Ikbke,Traf2,Tlr3,Pik3cd,Ldlr,Oas1g,Ppp2r2a,Akt3,Ifna1,Ddx58,Stat1,Tyk2,Ifna2,Nfkb1 |
| 2.593e-10 | -22.07 | Hepatitis C | KEGG pathways | ko05160 | 134 | 37 | 7931 | 713 |
Stat1,Nfkb1,Tyk2,Ifna2,Oas1g,Ifna1,Ddx58,Ppp2r2a,Akt3,Ikbke,Traf2,Ifit1,Ldlr,Pik3cd,Tlr3,Nfkbia,Stat3,Ifna5,Irf7,Ifit1bl1,Ifnar1,Tnf,Oas2,Oas3,Ifnb1,Oas1b,Nr1h3,Cdkn1a,Ifna6,Ppp2r1b,Socs3,Eif2ak2,Ifna4,Irf1,Ikbkg,Oas1a,Stat2 |
| 2.673e-10 | -22.04 | GO_RECEPTOR_BINDING | MSigDB lists | GO_RECEPTOR_BINDING | 1305 | 167 | 15632 | 1249 |
Rnd1,Cd74,Ifna2,Ccl3,Pdgfc,Ncoa7,Myd88,Traf2,Homer1,H2-Q6,Tnf,Prdx5,Itgb8,Tnfsf8,Stat3,Il18,Nr4a3,Ripk2,Il1b,Kitl,Plat,Pilrb1,Vcam1,Cxcl1,Serpine1,Pdgfrb,Osm,Tap2,Flrt2,Gdf15,Ccl5,Gja1,Fzd1,Cxcl2,Rapgef2,Inhba,Snx2,Il12rb1,Mmp13,Icosl,Cx3cl1,Irs2,Cdk5r1,Znrf3,Rtp4,Nck1,Spred1,Pilrb2,Pilra,Il27,Il15,Dnaja1,Hmga1,Ptpn2,Ets2,Sqstm1,Syk,Ifnb1,Ifna5,S1pr2,Mmp14,Stap1,Lyn,Itga5,Oasl1,C3,Tlr9,Sema4c,Ptk2,Ccl4,Jak2,Arf4,Rpgrip1l,Nos2,Casp8,Cav1,Sema3c,Ikbkg,Rnf14,Ednrb,S100a8,Med13,Csf1,Traf1,Fgr,Socs1,Hif1a,Icam1,Il1a,Lif,H2-Q7,Hck,Daxx,Notch1,Bmp2,Hspa1a,Timp1,Lrp4,Insl6,Src,Tapbp,Mdm2,Casp3,Fpr1,Clec4d,Il12b,Cxcl10,Tgfbi,Scyl2,Uchl1,Traf3ip2,Ptprj,Pf4,Plaur,Vegfc,Tnfsf10,Thbs1,Bambi,Il1rn,Plcl2,Sipa1l1,Cd86,Nampt,Tyk2,Csf3,Tlr1,Ifna6,Tnfsf15,Pdgfb,Ccl22,Phip,Tlr6,Angpt1,Tap1,Cdc42ep2,Ifna1,Dock4,Ccl12,Flrt3,H2-Q4,Cxcl14,Il18bp,Ccl2,Il6,Edn1,Adrb2,Tlr2,Sema4a,Stat1,Cd200,Kif5c,Ebi3,Tnfsf4,Nlgn2,Igf1r,Kdr,Cflar,Clcf1,Ptch1,Gna15,Tnfsf14,Il10,Ccne1,Jag1,Ccrl2,Sirt1,Plscr1 |
| 2.706e-10 | -22.03 | positive regulation of lymphocyte proliferation | biological process | GO:0050671 | 134 | 32 | 20694 | 1406 |
Il12rb1,Irs2,Clcf1,Il15,Ccl5,Cd40,Vcam1,Cd74,Ccdc88b,Cd274,Il12b,Il1b,Bcl6,Il18,Itgal,Stat5a,Ripk2,Syk,Cd80,Il6,Bst1,Cdkn1a,Tnfsf4,Cd86,Tlr9,Spn,Cd38,Nck1,Myd88,Icosl,Peli1,Tnfsf9 |
| 2.732e-10 | -22.02 | positive regulation of myeloid cell differentiation | biological process | GO:0045639 | 99 | 27 | 20694 | 1406 |
Lif,Hif1a,Acvr1b,Kitl,Jun,Fos,Stat5a,Tnf,Jag1,Ccl3,Gpr68,Pf4,Csf3,Stat3,Ikzf1,Casp8,Ccr1,Hcls1,Stat1,Inhba,Notch2,Trib1,Ccl5,Csf1,Cd74,Il12b,Isg15 |
| 2.778e-10 | -22.00 | Malaria | KEGG pathways | mmu05144 | 49 | 21 | 7931 | 713 |
Tlr2,Cd40,Csf3,Ccl2,Sele,Itgal,Tlr9,Thbs1,Il18,Il6,Vcam1,Myd88,Tnf,Icam1,Il1b,Gypc,Sdc2,Il10,Met,Ccl12,Sdc1 |
| 2.778e-10 | -22.00 | Malaria | KEGG pathways | ko05144 | 49 | 21 | 7931 | 713 |
Sdc2,Met,Il10,Ccl12,Sdc1,Gypc,Tnf,Icam1,Il1b,Il6,Vcam1,Myd88,Thbs1,Il18,Tlr9,Tlr2,Cd40,Sele,Csf3,Ccl2,Itgal |
| 2.826e-10 | -21.99 | HALLMARK_GLYCOLYSIS | MSigDB lists | HALLMARK_GLYCOLYSIS | 197 | 44 | 15632 | 1249 |
Txn1,Hk2,Sap30,Ddit4,Ext1,Ak4,Adora2b,Tgfbi,Ldha,Pgk1,Glrx,Eno1,Tpst1,Homer1,Slc16a3,P4ha2,Fut8,Gys1,Plod2,P4ha1,Eno2,Pdk3,Met,Egln3,Isg20,Ier3,Il13ra1,Fam162a,Gfpt1,Cited2,B4galt4,Agrn,Pcx,Sdc2,Vcan,Irs2,Gmppb,Sdc1,Pgm1,Tpi1,Rars,Me1,Gpc1,Gclc |
| 2.893e-10 | -21.96 | positive regulation of smooth muscle cell proliferation | biological process | GO:0048661 | 106 | 28 | 20694 | 1406 |
Egr1,Ccl5,Hmox1,Nr4a3,Calcrl,Edn1,Jak2,Nox1,Stat1,Igf1r,Ptk2,Pdgfrb,Mmp9,Il18,Myc,Mdm2,Abcc4,Tnf,Ptgs2,Cx3cl1,Jun,Ptafr,Hif1a,Il6,Pdgfb,Nampt,Myd88,Thbs1 |
| 2.893e-10 | -21.96 | GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_DN | MSigDB lists | GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_DN | 190 | 43 | 15632 | 1249 |
Slc2a1,Il6,Fcgr2b,Cebpd,Gadd45g,Errfi1,Mcoln2,Cdkn2d,Tpi1,Ch25h,Sphk1,Gmppb,Pttg1,Ube2f,Myd88,Ahr,Rgl1,Cep350,Hdc,Gbp7,Irf8,Ifit3,Noc4l,Plscr1,Procr,Ddit4,Maff,Rac3,Socs3,Ptger4,Ifit3b,Cxcl10,Map3k8,Phyh,Rcan1,Irf1,Plat,Ccl4,Gtpbp2,Dr1,Nfil3,Dusp16,Pfkl |
| 2.895e-10 | -21.96 | response to peptide | biological process | GO:1901652 | 334 | 56 | 20694 | 1406 |
Stat1,Tlr6,Jak2,Cav1,Tnfaip3,Nfkb1,Nr4a3,Mdm2,Il18,Sirt1,Mmp9,Trib3,Akt3,Notch1,Cyfip1,Ripk2,Sesn3,Serpina3f,Jag1,Timeless,Casp4,Prnp,Stat3,Src,Fpr2,Stat2,Socs7,Igf1r,Phip,Stxbp3,Rhoq,Vcam1,Kat2b,Irs2,Nod2,Nod1,Rab10,Egr1,Icam1,Itga4,Ednrb,Ptpn2,Ptk2,Stat4,Cacybp,Pde3b,Egr2,Stat5a,Serpina3g,Slc9a1,Adrb2,Nfkbia,Agtrap,Irf1,Nr4a1,Fcgr2b |
| 2.900e-10 | -21.96 | GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 1049 | 141 | 15632 | 1249 |
Kat2b,Mul1,Cx3cl1,Il15,Cd34,Cd80,Gpc1,Tspo,Hmga1,Cited2,Syk,S1pr2,Ap3b1,Scarf1,Pde5a,Bnip3,Pla2g4a,Mmp14,Lpar1,Trib1,Lyn,Mtdh,Egr3,Itga5,Rac3,C3,Jak2,Casp8,Nfkb1,Mmd,Csf1,Zeb1,Spen,Cd74,Prdm1,Etv5,Irak3,Tnfaip3,Sav1,Bcl6,Serp1,Tcf4,Tnf,Phldb1,Ddhd1,Glipr2,Mecp2,Gpr68,Rab21,Hmox1,Ripk2,Il1b,Kitl,Gcnt2,Flrt2,Hopx,Serpine1,Pdgfrb,Map2k1,Ccr1,Gdf15,Gja1,Ccl5,Myadm,Inhba,Il12rb1,Rapgef2,Pdlim7,Nlrp3,Il4ra,Lrp8,Egr1,Mark2,Htr2a,Msr1,Fos,Jun,Ezr,Cx3cr1,Flt1,Agrn,Flrt3,Triobp,Ccr3,Edn1,Il6,Myc,Acvr1b,Adrb2,Tnfsf4,Socs3,Nlgn2,Clcf1,Hcls1,Kdr,Fam20c,Tnfsf14,P2ry2,Ptch1,Ccne1,Jag1,Sirt1,Eef1e1,Rasgrp1,Cysltr2,Il1a,Hif1a,Isg15,Sphk1,Hlx,Pml,Lif,Notch1,Cd83,Bmp2,Rgs14,Cd40,Src,Ehd1,Axl,Acvr1,Ccnd1,Kdm5b,Acvrl1,Pnp2,Ptgs2,Il12b,Ptger4,Zc3h12a,Vegfc,Pf4,Cmklr1,Bambi,Thbs1,Cd86,Pik3r6,Junb,Csf3,Hap1,Pdgfb,Scn1b |
| 2.906e-10 | -21.96 | GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP | MSigDB lists | GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP | 169 | 40 | 15632 | 1249 |
Isg20,Ccne1,Csrp1,Psat1,Ifit1bl2,Casp4,Plod2,Ifit3,Cd86,Adam19,Gca,Clic4,Acsl5,Trafd1,Stat1,Ifit3b,Cxcl10,Mcm6,Nr4a3,Aida,Egr2,Ly75,Rsad2,Dhx58,Cd200r4,Fgl2,Eif2ak2,Ifit1bl1,Cenpe,Rbbp8,Zbp1,Cd38,Ripk3,Ddx60,Aim2,Tpx2,Ifih1,Kdm4a,Cyth3,Usp18 |
| 2.932e-10 | -21.95 | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | 183 | 42 | 15632 | 1249 |
Map3k8,Trib1,Egr3,Cldnd1,Irak2,Gca,Cenpj,Layn,Heatr6,Sipa1l1,Osm,Gna15,Tnfrsf1b,Hk1,Birc3,Mthfd1l,Ttc9c,Snx10,Tor3a,Pde4b,Nampt,Slc39a14,Sap30,Kat2b,Pttg1,Lrp8,Prdm1,Plagl2,Batf,Eno1,Rbbp8,Cyfip1,Swap70,Tnf,Gpr68,Nod2,Nfkbie,Chst11,Rab11fip1,Dusp2,Irf4,Sat1 |
| 2.932e-10 | -21.95 | GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_UP | MSigDB lists | GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_UP | 183 | 42 | 15632 | 1249 |
Ass1,Agrn,Ppp1r14b,Oas3,Gbp4,Gbp9,Parp14,Tapbp,Parp9,Ddx60,Psme1,Il4ra,Traf1,Rtp4,Usp18,Lipg,Prpf38a,Gbp2,Tap1,Mark2,Csrp1,Adap2,Ifit3,Rnaset2a,Cysltr2,Srxn1,Parp12,Oas1a,Oas1g,Stat1,Ifi35,Cxcl10,Tapbpl,Ifit3b,Grina,Inpp1,Tnfaip2,Pmepa1,Trafd1,Keap1,Ptges,Rnaset2b |
| 2.932e-10 | -21.95 | GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDC_UP | 183 | 42 | 15632 | 1249 |
Lpar1,Ttc39b,Ddx4,Actb,Rbms1,Kdr,Gca,Asf1a,Rnaset2b,Epsti1,Dio2,Nlgn2,Ankib1,Atm,Mov10,Rnaset2a,Irf8,Akt3,Htra1,Dgka,Oas2,Tbc1d13,Egr1,Rnf135,Slc30a1,Isg15,Arrdc4,Rbms2,Cd80,Fbxo4,Cd164,Apaf1,Klf3,Lrp4,Rgs14,Tpst1,Stat3,Abcb1a,Batf2,Ogfrl1,Psd,Nfkbie |
| 2.937e-10 | -21.95 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN | 176 | 41 | 15632 | 1249 |
Dusp1,Gadd45b,N4bp1,Pik3r5,P2ry12,Tpst1,Ets2,Sat1,Peli1,Stk40,Nupr1,Cyth3,Cd180,Rnf135,Dtx3l,Gbe1,Sgk3,Tle3,Irak3,Rgl1,Fcgr4,Slc31a2,Il10,Samsn1,Plod2,Adap2,Plekha2,Sap30,Htra1,Gbgt1,Stx6,Ell2,Fcho2,Arid5b,Map3k8,Azi2,Tlr2,Cmklr1,Ralgds,Lacc1,Tagap |
| 2.996e-10 | -21.93 | GO_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS | 92 | 28 | 15632 | 1249 |
Nmi,Tlr1,Inhba,Nfkb1,Cd86,Il10,Thbs1,Il1b,Igf2bp2,Hmox1,Tlr3,Ebi3,Tlr9,Ptafr,Il12b,Irf1,Il6,Irf4,Errfi1,Syk,Spn,Tnf,Cd80,Tnfrsf8,Il27,Tlr6,Mapkapk2,Il1a |
| 2.996e-10 | -21.93 | ZHU_CMV_24_HR_UP | MSigDB lists | ZHU_CMV_24_HR_UP | 92 | 28 | 15632 | 1249 |
Trim12c,Isg15,Egr1,Mark2,Tap1,Eno1,Nfkbia,Nr4a1,Ifit1bl1,Psma6,Pla2g4a,Pnp2,Pim1,Irf1,Cd55,Oas1g,Stip1,Nampt,Ifit1bl2,Eno2,Gch1,Tuba4a,Nfkb1,Oas1a,Slc39a14,Trim21,Trim26,Alas1 |
| 3.200e-10 | -21.86 | positive regulation of chemokine production | biological process | GO:0032722 | 62 | 21 | 20694 | 1406 |
Il1b,Cd74,Lgals9,Adora2b,Il18,Myd88,Tlr9,Hdac1,P2ry2,Tlr2,Il1a,Eif2ak2,Ccl5,Egr1,Tnf,Il4ra,Nod2,Ripk2,Tlr3,Il6,Mcoln2 |
| 3.274e-10 | -21.84 | GO_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | 123 | 33 | 15632 | 1249 |
Cd86,Pik3r6,Nfkbid,Inhba,Il12rb1,Rasgrp1,Zeb1,Irf1,Il12b,Egr3,Tnfsf4,Ripk2,Il1b,Ptpn2,Bcl6,Axl,Syk,Ap3b1,Ifnb1,Irf4,Mmp14,Pnp2,Il6,Cd74,Il4ra,Nlrp3,Fas,Hlx,Prdm1,Il15,Cd83,Il27,Cd80 |
| 3.336e-10 | -21.82 | defense response to bacterium | biological process | GO:0042742 | 264 | 48 | 20694 | 1406 |
Gsdmd,Il12b,Gbp8,Ankrd17,Fgr,Notch2,Serpine1,Ifnb1,Nod1,Nod2,Serpinb9,Slamf8,Gbp2,Fcgr1,Tlr9,Myd88,Il10,Syk,Gbp7,Iigp1,Gbp9,Tnf,Plac8,Optn,Ifna1,Acp5,Hp,Irf8,Nlrp3,Isg15,Nlrc4,Tnfrsf14,Clec4e,Tlr2,Clec4d,Spn,Trem1,Hck,Fpr2,Lcn2,Gbp3,Tnfsf8,Slpi,Klrk1,Gbp2b,Ripk2,Irgm2,Nos2 |
| 3.415e-10 | -21.80 | toll-like receptor signaling pathway | biological process | GO:0002224 | 51 | 19 | 20694 | 1406 |
Tlr1,Cd86,Mapkapk2,Lgals9,Myd88,Cd14,Tlr9,Nfkbia,Irak2,Cd300lf,Irak3,Prkce,Tnip3,Tlr2,Tnf,Tnip1,Ripk2,Tlr6,Tlr3 |
| 3.444e-10 | -21.79 | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP | 163 | 39 | 15632 | 1249 |
Inhba,Rnf19a,Ccrl2,Egln3,Cxcl2,Srxn1,Csf1,Tnfsf15,Tnfsf14,Gem,Rabgef1,Txn1,Cdkn1a,Snapc1,Cxcl1,Rgs1,Ptgs2,Trib1,Nsmaf,Rab20,Fndc3a,Dusp5,B3gnt5,Dusp4,Edn1,Egr2,Pnp2,Homer1,Jun,Ets2,Dusp1,Usp53,Txnrd1,Dusp14,Ubash3b,Upp1,Sgms2,St3gal6,Csrnp1 |
| 3.451e-10 | -21.79 | HALLMARK_P53_PATHWAY | MSigDB lists | HALLMARK_P53_PATHWAY | 191 | 43 | 15632 | 1249 |
Ralgds,Trafd1,Hmox1,Rnf19b,Trib3,Ddit4,Btg2,Dgka,Plk2,Ppp1r15a,Bmp2,Notch1,Apaf1,Nupr1,Lif,Mxd1,Plk3,Socs1,Sphk1,Sertad3,Il1a,Upp1,Sat1,Mdm2,Casp1,Abcc5,Rhbdf2,Cd82,Cdkn1a,Fam162a,Dram1,Ier3,Acvr1b,Procr,Tap1,Atf3,Fas,Cdk5r1,Sdc1,Ccnd2,Slc7a11,Jun,Fos |
| 3.451e-10 | -21.79 | MANALO_HYPOXIA_UP | MSigDB lists | MANALO_HYPOXIA_UP | 191 | 43 | 15632 | 1249 |
Zhx2,Vegfc,Sec24a,Tapbpl,Lox,Tgfbi,Ak4,Maff,Inhba,Phlda1,Ddit4,Pdgfb,Serpine1,Dusp6,Tnfaip3,Tsku,Rgs3,Ccng2,Bcl6,Gypc,P4ha2,Axl,Ier3,Acvr1b,Cd200,Filip1l,Egln3,Htra1,Plod2,P4ha1,Eno2,Tnfrsf14,Gpc1,Col4a2,Gbe1,Cx3cl1,Col18a1,Rai14,Edn1,Bnip3,Spsb1,Hivep2,Gadd45b |
| 3.512e-10 | -21.77 | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | 184 | 42 | 15632 | 1249 |
Gja1,Nampt,Plek,Tor3a,Samsn1,Akt3,Rasgrp1,Hivep3,Ptger4,Casp7,Tnfsf4,Rcsd1,Cd82,Bcl2a1a,Frmd6,Nfil3,Epsti1,Bcl2a1b,Dusp2,Gbp4,Slc15a3,Gbp9,Parp14,Irgm2,Dock10,Ccng2,Dusp4,Cpd,Bcl2a1d,Mapkapk2,Lif,Mxd1,Slc30a1,Icam1,Prnp,Stat2,Pde3b,1600014C10Rik,Extl2,Tap1,Relb,Ahr |
| 3.534e-10 | -21.76 | GSE360_CTRL_VS_L_DONOVANI_DC_DN | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_DC_DN | 177 | 41 | 15632 | 1249 |
Cd83,Cd34,Relb,Angpt1,Ahr,Traf1,Irs2,Il4ra,Fcgr2b,Rhoq,Rai14,Ly75,Ifrd1,Cebpd,Nfkbia,Ehd1,Gypc,Cst7,Sqstm1,N4bp1,Ets2,Adam19,Ccl4,Nfkb2,Il15ra,Kdm6b,Casp7,Dusp5,Ell2,Mmp9,Il2rg,Ier3,Nrp2,Slpi,Tdrd7,Stx11,Txn1,Eno2,Rgl1,Hopx,Map2k1 |
| 3.659e-10 | -21.73 | positive regulation of autophagy | biological process | GO:0010508 | 121 | 30 | 20694 | 1406 |
Hk2,Larp1,Mtdh,Ikbkg,Trim21,Nod1,Nod2,Tlr2,Hmox1,Bnip3,Optn,Sirt1,Zc3h12a,Trim13,Mefv,Sh3bp4,Hif1a,Kdr,Sesn3,Irgm2,Mul1,Ripk2,Plk3,Adrb2,Tlr9,Plk2,Bcl2l11,Irgm1,Map2k1,Pim2 |
| 3.667e-10 | -21.73 | regulation of leukocyte apoptotic process | biological process | GO:2000106 | 107 | 28 | 20694 | 1406 |
Fcgr2b,Tnfsf4,Hcls1,Casp8,Il10,Bcl2a1a,Rapgef2,Pik3cd,Stat5a,Kitl,Hif1a,Arg2,Cd274,Cd74,Axl,Sirt1,Il18,Myc,Hcar2,Ripk3,Nr4a3,Serpinb9,Ccl5,Nfkbid,Slc7a11,Irs2,Nod2,Lyn |
| 3.747e-10 | -21.70 | response to type I interferon | biological process | GO:0034340 | 23 | 13 | 20694 | 1406 |
Shfl,Irf7,Ifnb1,Ikbke,Stat1,Ifnar1,Trim56,Stat2,Isg15,Ifitm1,Oas2,Ifna1,Myd88 |
| 3.801e-10 | -21.69 | REACTOME_ACTIVATED_TLR4_SIGNALLING | MSigDB lists | REACTOME_ACTIVATED_TLR4_SIGNALLING | 87 | 27 | 15632 | 1249 |
Irak2,Ikbke,Nfkb2,Ppp2r1b,Tlr2,Map2k4,Tlr3,Ripk2,Nfkbib,Tlr1,Map2k1,Irf7,Dusp6,Ikbkg,Irak3,Myd88,Nod1,Cd14,Tab2,Tlr6,Mapkapk2,Nod2,Dusp4,Peli1,Fos,Jun,Nfkbia |
| 3.801e-10 | -21.69 | IRF1_01 | MSigDB lists | IRF1_01 | 228 | 48 | 15632 | 1249 |
Ccl5,Stx11,Pcgf5,Tmem229b,Slamf8,Cxcl10,Lox,Dio2,Il15ra,Tfec,5430427O19Rik,Ehd1,Psmb9,Sat1,Egr2,Tlk2,Prdx5,Atp13a1,Tapbp,Hlx,Lif,Ddx58,Usp18,Pigv,Dtx3l,Psmb10,Isg15,Pdgfc,Psmb8,Ltbp2,Lmo4,Trim21,Med13,Syne2,Xaf1,Kpna3,Gsdmd,Casz1,Bbx,Il6,Chst11,Ifnb1,Atf3,Bcor,Il27,Col4a2,Tap1,Dnase1l3 |
| 3.873e-10 | -21.67 | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_UP | MSigDB lists | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_UP | 150 | 37 | 15632 | 1249 |
Dusp1,Klf3,Cx3cr1,Cst7,Casp1,Cd200r4,Rsad2,Bbx,Ddx58,Ccnd2,Stat2,Ifih1,Irf2,Ddx60,Nck1,Cd38,Klf2,Gem,Cep350,Plod2,Casp4,Junb,Arid4a,Abtb2,Ccl5,Isg20,Slpi,Phyh,Nsmaf,Nr4a3,Tnfsf4,Cd55,Kif5c,Lrrc8c,Gca,Tnfsf10,Chd9 |
| 3.930e-10 | -21.66 | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | MSigDB lists | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | 105 | 30 | 15632 | 1249 |
Jag1,Kctd12,Ddit4,Fabp7,Phlda1,Plk2,Ppp1r15a,Asns,Serpine1,Eno2,Psat1,Gdf15,Fam162a,Dcbld2,Pgk1,Glrx,Ldlr,Thbs1,Ak4,Trib3,Nox1,Hmox1,Vcan,Cxcl14,Phgdh,Jun,Slc7a11,Slc30a1,Atf3,Nupr1 |
| 4.050e-10 | -21.63 | Hemostasis | REACTOME pathways | R-MMU-109582 | 515 | 88 | 8608 | 757 |
F11r,Maff,Prkce,Pf4,Lyn,Slc16a3,Stxbp3,Ifna5,Ehd1,Srgn,Fgr,Lcp2,Pcdh7,Itga5,Ptgir,Serpine1,Slc16a1,Ifna6,Pik3cd,Sdc1,Sdc2,Gpc1,Gna15,Jak2,Olr1,Serpinb2,Pik3r6,Kif9,Mafk,Ifnb1,Lrp8,Carmil1,Dgkh,Sell,H3f3b,Pde1b,Slc7a11,Cd74,Ifna4,Nos2,Pde5a,Trem1,Ptk2,Procr,Itga4,Endod1,Sdc4,Sele,Atp2b4,Syk,P2ry12,Dgka,Vegfc,Src,Gtpbp2,F10,Angpt1,Plat,Irf2,Plaur,Timp1,Itpr1,Cav1,Mafg,Cenpe,Irf7,Pdpn,Slc7a5,Pde3b,Spn,Ifna2,Plau,Slc7a8,Il2rg,Ifna1,Irf1,Pla2g4a,Thbs1,Pdgfb,Tuba4a,Kif3c,Serpina3f,Prkar2b,Rasgrp1,Plek,Pik3r5,Itgal,Abcc4 |
| 4.071e-10 | -21.62 | vasculature development | biological process | GO:0001944 | 559 | 79 | 20694 | 1406 |
Pdpn,Cx3cl1,Jun,Socs3,Kdr,Vegfc,Ptger4,Cited2,Syk,Pde3b,Plpp3,Tnfsf4,Ccl12,Acvr1,Nr4a1,Casp8,Ccl2,Col4a2,Angpt1,Plau,Acvrl1,Prdm1,Egr1,Jmjd6,Col18a1,Calcrl,Notch2,Edn1,Wars,Nox1,Ankrd17,Clic4,Antxr1,Tnfaip2,Ccr3,Prkx,Itgb8,Ptk2,Junb,Fzd5,Slc4a7,Pdgfrb,Sec24b,Lox,Jag1,Ptgs2,Hif1a,Flt1,Pdgfb,Lif,Spred1,Map2k1,Ldlr,Ptprj,Sema4a,Egr3,Rapgef2,Nrp2,Sema3c,Thbs1,Hmox1,Ahr,Cav1,Errfi1,Itgav,Gja1,Cemip2,Crkl,Sphk1,Notch1,Hhex,Pik3r6,Prokr1,Sirt1,Il18,Zc3h12a,Sgcb,Mdm2,Tiparp |
| 4.095e-10 | -21.62 | cellular response to toxic substance | biological process | GO:0097237 | 151 | 34 | 20694 | 1406 |
Kdr,Srxn1,Il6,Selenow,Pdgfb,Tnf,Ccl7,Daxx,Sod2,Src,Timeless,Prdx1,Abtb2,S100a8,Lcn2,Prdx5,Slc31a1,Sphk1,Esd,Egr1,Ripk3,Hmox1,Prkce,Tnfaip3,Nfkb1,Zc3h12a,Nqo1,Pdgfrb,Actb,Sirt1,Bnip3,Kdm6b,Hp,Axl |
| 4.101e-10 | -21.61 | negative regulation of innate immune response | biological process | GO:0045824 | 57 | 20 | 20694 | 1406 |
Ptpn2,Smpdl3b,Slamf8,Irak3,Clec2d,Trafd1,Samhd1,Dhx58,Nmi,Tap1,Lgals9,Ccr1,Parp14,Acod1,Nlrc5,Adar,Serpinb9,Tap2,Mul1,Tnfaip3 |
| 4.177e-10 | -21.60 | GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_DN | 164 | 39 | 15632 | 1249 |
Zyx,Csf3r,Dse,Timp1,Sod2,Cpd,Vcan,Nod2,Slc15a3,Slco3a1,Hif1a,Icam1,Prrg4,Egr1,Cdkn2d,Mxd1,Tle3,P2ry2,Gna15,Ppp1r15a,S100a8,Plek,Bst1,Rtn2,Rab20,Tlr2,Fpr1,Acsl1,Grina,Socs3,Max,Rnf19b,Cdkn1a,Tfec,Nfil3,Plaur,Arf4,Fscn1,Il1rn |
| 4.199e-10 | -21.59 | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_UP | 185 | 42 | 15632 | 1249 |
Socs3,Rnf19b,Rab20,Arid5b,Slfn9,Gfi1,Lrrc8c,Nfil3,Pmepa1,Rcl1,Hk1,Junb,Slc13a3,Snx10,Vps54,Ext1,Egln3,Etv6,Oas2,Nek6,Cdkn2d,Pgs1,Prdm1,Slc30a4,Il4ra,Icam1,Ciapin1,Calcrl,Batf,Ahr,Chmp4b,Txnrd1,Plac8,Jun,Ptpn2,Timp1,Tnfsf8,Slfn8,Irf4,Fut8,Gsr,Gadd45g |
| 4.199e-10 | -21.59 | GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP | MSigDB lists | GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP | 185 | 42 | 15632 | 1249 |
Casp4,Rrs1,Hopx,Ccne1,Ccr1,Tyk2,Cxcl2,Pdlim7,Timeless,Flnb,St3gal5,Procr,Ext1,Sema4a,Il2rg,Cox18,Ell2,Itga5,Hmox1,Abcc1,Igf2bp2,Esd,Tnfaip2,Ikbke,Inpp1,Kdr,Clcn7,Slc2a1,Eno1,Msr1,Txnrd1,Cx3cr1,Gsr,Vcan,Ccl2,Gclm,Fgr,Sdc1,Plk3,Abr,Myo10,Bmp2 |
| 4.238e-10 | -21.58 | KRAS.DF.V1_UP | MSigDB lists | KRAS.DF.V1_UP | 171 | 40 | 15632 | 1249 |
Vcan,Ccng2,Hspa2,Fut8,Spry2,Peli1,Pdpn,Nat2,Ifi44,Arhgef3,Bcl6,Ifit1bl1,Map3k6,Flrt3,Mvp,Plau,Gng11,Cutc,Bmp2,Lrp8,Inhba,Csf3,Cxcl2,Akt3,Isg20,Sap30,Procr,Pid1,Serpine1,Ifit1bl2,Slc4a7,Gch1,Vegfc,Glrx,Jak2,Hcls1,Plat,Tlr2,Etnk1,Ifi35 |
| 4.238e-10 | -21.58 | GSE37301_CD4_TCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE37301_CD4_TCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 171 | 40 | 15632 | 1249 |
Evl,Usp18,Ifih1,Psmb10,Traf1,Rtp4,Rras2,Nod1,Cd83,Ahr,Rbl1,Hivep2,Bcl2l11,Arid5a,Itpr1,Serp1,Ikzf1,Tnfsf8,Phlpp1,Arhgap26,Max,Endod1,Trib1,Sema4a,Tmem67,Vcam1,Tnip1,Ikbke,Ppfibp2,Zhx2,Abtb2,Pde4b,Jarid2,Sesn3,Ccl5,Map4k4,Cd86,Tnfsf14,Plscr1,Rnf19a |
| 4.238e-10 | -21.58 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN | 171 | 40 | 15632 | 1249 |
Slc31a1,Kif5c,Acsl1,Tlr2,Irf1,Ptgs2,Bcl2a1a,Cxcl1,Wdr43,Csrp1,Pde4b,Nampt,Slc4a7,Plod2,Serpine1,Psme2,Zfp36,Htra1,Inpp5b,Ddit4,Vasp,Slc30a4,Aim2,Socs1,Kat2b,Gys1,Olr1,Gbp2,Tnfaip3,Cd38,Bcl2a1b,P4ha2,Ptpn2,Timp1,Psmb9,Mmp14,Tnc,Nqo1,Bcl2a1d,Vcan |
| 4.244e-10 | -21.58 | GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_UP | MSigDB lists | GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_UP | 178 | 41 | 15632 | 1249 |
Tap1,Sla,Ifih1,Psmb10,Rhoh,Psme1,H2-Q7,Prkce,Gpr18,Psmb9,Timp1,H2-Q6,Cst7,H2-Q4,Hsd17b7,H3f3b,Bambi,Tnfsf10,Slc25a22,Ifit3b,Irf1,Slamf8,Stat1,Ifi35,Hmgcs1,Stat4,Ccrl2,Phlda1,Psme2,Antxr1,Nmi,Isg20,Trim21,Bcl9,Ube2l6,Atp6v1d,Lcp2,Ifit3,Ccr1,Jarid2,Psmb8 |
| 4.252e-10 | -21.58 | Chagas disease (American trypanosomiasis) | KEGG pathways | mmu05142 | 101 | 31 | 7931 | 713 |
Tnf,Fas,Nfkbia,Pik3cd,Il10,Casp8,Akt3,Tlr2,Ppp2r2a,Nos2,Gna15,Jun,Nfkb1,Ccl3,Tlr9,C3,Il12b,Il1b,Il6,Ikbkg,Myd88,Ccl12,Ppp2r1b,Tlr6,Fos,Ccl2,Cflar,Map2k4,Ccl5,Serpine1,Ifnb1 |
| 4.252e-10 | -21.58 | Chagas disease (American trypanosomiasis) | KEGG pathways | ko05142 | 101 | 31 | 7931 | 713 |
Ccl12,Ppp2r1b,Il12b,Il1b,C3,Myd88,Ikbkg,Il6,Serpine1,Ifnb1,Ccl2,Cflar,Fos,Tlr6,Ccl5,Map2k4,Il10,Pik3cd,Casp8,Tnf,Nfkbia,Fas,Nfkb1,Jun,Tlr9,Ccl3,Nos2,Tlr2,Ppp2r2a,Akt3,Gna15 |
| 4.498e-10 | -21.52 | HIN200/IF120x | interpro domains | IPR004021 | 10 | 9 | 19984 | 1430 |
Ifi207,Aim2,Mndal,Ifi214,Ifi204,Ifi211,Ifi209,Ifi205,Ifi203 |
| 4.723e-10 | -21.47 | GO_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | MSigDB lists | GO_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | 200 | 44 | 15632 | 1249 |
Cav1,Rictor,Lyn,Socs3,Itga5,Jak2,Clcf1,Hcls1,Rap2c,Ptpn2,Syk,Il6,Stap1,Prkce,Lrp8,Tnfrsf14,Angpt1,Il15,Cd80,Htr2a,Samsn1,Osm,Ccl5,Csf3,Pdgfb,Il18,Il12b,Ptger4,Ripk2,Vegfc,Kitl,Cd40,Src,Hsph1,Lrp4,Ifnar1,Errfi1,Stat3,Cd74,Icam1,Socs1,Lif,Pdgfc,Mvp |
| 4.771e-10 | -21.46 | HIN | pfam domains | PF02760 | 10 | 9 | 18711 | 1348 |
Ifi203,Aim2,Ifi209,Mndal,Ifi205,Ifi204,Ifi211,Ifi207,Ifi214 |
| 4.869e-10 | -21.44 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | 355 | 64 | 15632 | 1249 |
Sdc2,B4galt4,Tspan3,Ets2,Rhof,Fam43a,Ezr,H2-Q4,Syk,Psip1,Bcl2l11,Bcl2a1b,Spred1,Pde3b,Fbxo4,Gpc1,Arl4a,Jag1,Syne2,Met,Procr,Isg20,Ptch1,Lmo4,Plod2,Mob3c,Cdkn1a,Pmepa1,Cflar,Cacna1d,Ldlr,Rap2c,Dram1,Il13ra1,Stat1,Itga5,Mafk,Gpr68,B3gnt5,Bcl2a1d,H2-Q6,Mtus1,P4ha2,Ehd1,Klf6,Myo10,Batf,Pbx1,H2-Q7,Lrch3,Ppp2r3a,Hk2,Sap30,Pdlim7,Daam1,Slc4a7,Il15ra,Vegfc,Plaur,Igf2bp2,Ptges,Bcl2a1a,Kif3c,Cd55 |
| 4.889e-10 | -21.44 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN | 193 | 43 | 15632 | 1249 |
Tnfrsf1b,Casp4,Plscr1,Il18rap,Ell2,Odc1,Ccl4,Adam19,Lrrc8c,Bcl2a1b,H2-Q4,Gadd45b,Fos,Fcgr2b,Cox17,Ccl5,Snx10,Txn1,Fosb,Hopx,Rnf19b,Pim1,Cldnd1,Tnfsf10,Bcl2a1a,Glrx,N4bp1,Cst7,Casp1,Klf6,H2-Q6,Cish,Bcl2a1d,Fgl2,Errfi1,Itga4,H2-Q7,Slco3a1,St3gal6,Fgr,Gbp3,Tnfaip3,Mdfic |
| 4.889e-10 | -21.44 | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN | 193 | 43 | 15632 | 1249 |
Hopx,Myadm,Gja1,Ccl5,Txn1,Snx10,Adora2a,Hk2,Serpinb9,Rnf19b,Glrx,Cldnd1,Bcl2a1a,H2-Q6,Casp1,Bcl2a1d,Errfi1,Fgl2,Carhsp1,Rhoq,Casp3,Fgr,Gbp3,St3gal6,H2-Q7,Itga4,Prdm1,Mdfic,Sla,Casp4,Itgal,Il18rap,Plscr1,Ell2,Casp7,Ccl4,Actb,Bcl2a1b,H2-Q4,Cox17,Fcgr2b,Pttg1,Prdx1 |
| 5.014e-10 | -21.41 | GSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_DN | MSigDB lists | GSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_DN | 186 | 42 | 15632 | 1249 |
Cd38,Herc3,Gbp3,Aldh1b1,Ccnd2,Cd74,Cdkn2d,Bcor,Asap3,Hspa2,B3gnt5,Treml2,Nfkbie,Prkce,Ppp2r5a,D1Ertd622e,Ikzf1,Tank,P2ry12,Gpr18,Gsdmd,Snn,Adam19,Tmem123,Tax1bp1,Lyn,Kcna3,Ripk2,Uchl1,Ell2,Stx11,Slamf9,Slpi,H2-Aa,Tifa,Trim26,Plekha2,Heatr6,Atp6v1d,Cnp,Dcun1d3,Birc3 |
| 5.014e-10 | -21.41 | GSE17721_LPS_VS_POLYIC_12H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_12H_BMDC_DN | 186 | 42 | 15632 | 1249 |
Flt1,Phldb1,Clmp,Itpr1,Gpsm2,Sat1,Phgdh,Batf2,Nat2,Ap3b1,Tmem176b,Nck1,Hhex,Sdc1,Rnf34,Gng11,Rgs3,Prpf38a,Rhoc,Angpt1,Atp11b,Samhd1,Slc12a9,Cdyl,Clec4n,Slfn4,Tap2,Ptch1,Eya4,Rhou,Tlr3,Tlr9,Irf1,Ddx4,Vcam1,Slfn3,Asf1a,Tnfsf10,Gcnt2,Epsti1,Il15ra,Nfil3 |
| 5.014e-10 | -21.41 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_UP | 186 | 42 | 15632 | 1249 |
Stap1,Abcb1a,Lztfl1,Chst11,Fgl2,Cept1,Plac8,Ifit1bl1,Acpp,Ttc39c,Pde3b,Slamf7,Rnf34,Gbp2,Ncoa7,Tmem176b,Prdm1,Rnf135,Ccnd2,Cysltr2,Rasgrp1,Tmem176a,Il18rap,Trim56,Il12rb1,Ahrr,Jdp2,Ccl5,Ccr1,Ifit1bl2,Hopx,Ppm1k,Rgs1,Adam19,Mitd1,Inpp1,Ldlr,Osbpl3,Stat1,Nr4a3,Fam111a,Rcn1 |
| 5.014e-10 | -21.41 | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN | MSigDB lists | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN | 186 | 42 | 15632 | 1249 |
Cdkn1a,Dnajb2,Epsti1,Ralgds,Bcl2a1a,Osbpl3,Ier3,Kif5c,Endod1,Tlr3,Adora2a,Il18rap,Stx11,Smpdl3b,Plscr1,Srxn1,Cysltr2,Pid1,Asns,Tnfsf14,Jdp2,Myadm,Ccl5,Gbp3,Traf1,Cdk5r1,St3gal6,Plagl1,Hif1a,Tpi1,Gpr68,B3gnt5,Bcl2a1d,Arhgap26,Abcb1a,Trip10,Tspan3,Ttc39c,Casp1,Cst7,Apobec3,Bcl2a1b |
| 5.088e-10 | -21.40 | GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_DN | MSigDB lists | GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_DN | 179 | 41 | 15632 | 1249 |
Relb,Ifit1,Rtp4,Sell,Dmxl2,Spata13,Icam1,Pml,B3gnt5,Rsad2,Ifi44,Gbp9,Rhoq,Gbp4,Ikzf1,Tpst1,Ifit1bl1,Plac8,Glrx,Hsd17b7,Nlgn2,Bambi,Ccl4,Clcf1,Notch2,Osbpl3,Ms4a6d,Osgin2,Ak4,Traf3ip2,Oasl1,Syne2,Ccdc25,Vasn,H2-Aa,Bcorl1,Reps1,Gbp7,Cd86,Ccl5,Ifit1bl2 |
| 5.156e-10 | -21.39 | NFKB_C | MSigDB lists | NFKB_C | 245 | 50 | 15632 | 1249 |
Ptges,5430427O19Rik,Zhx2,Ralgds,Nfkb2,Vcam1,Il1rn,Cxcl10,Map3k8,Phf6,Ptgs2,Slamf8,Gng4,Ptprj,Tnfsf15,Rab10,Col11a2,Ccl5,Rgl1,Rnd1,Il1a,Icam1,Cd74,Zfp800,Egr2,Itgb8,Cd40,Parp8,Mob3c,Tnip1,Rap2c,Irf1,Tnip3,Uaca,Egr3,Nfkbib,Lcn2,Nos2,Il27,Ccl22,Ifnb1,S1pr2,Mllt6,Rin2,Il4i1,Lrch1,Dnaja1,Fos,Gadd45b,Nfkbia |
| 5.338e-10 | -21.35 | response to endogenous stimulus | biological process | GO:0009719 | 1213 | 139 | 20694 | 1406 |
Me1,Myd88,Col4a2,Acvrl1,Agtrap,Pml,Zyx,Fcgr2b,Cacybp,Syk,Cited2,Pde3b,Sh3bp4,Stat4,Egr2,Bambi,P2ry12,Jun,Daxx,Tnf,Gdf15,Pde4b,Junb,Ednrb,Actb,Gclc,Il1rn,Igf1r,Fut8,Larp1,Hmgcs1,Vcam1,Phip,Stxbp3,Irs2,Kat2b,Ifnb1,Nod1,Icam1,Rab10,Egr1,Timeless,Cd38,Rapgef2,Cpeb4,Nmral1,Prnp,Bmp2,Il6,Cyfip1,Acsl1,Acvr1b,Fos,Ier2,Cflar,Lox,Mdm2,Sirt1,Pdgfc,Trib3,Htr2b,Acod1,Itpr1,Casp3,Nfkb1,Lyn,Cav1,Nr4a3,Cdk5r1,Prkce,Ccnd1,Ahr,Apaf1,Tlr9,Adrb2,Slc9a1,Ccl2,Irf1,Il10,Ezr,Tnfsf4,Glrx,Ddit4,Nr4a1,Acvr1,Atp2b4,Ptger4,Mecp2,Mmp13,Stat5a,Ehd1,Socs1,Serpina3g,Itga4,Zfp36,Dcp1a,Pdgfrb,Ptpn2,Ptk2,Mmp14,Casp7,Nr1h3,Zeb1,Dnaja1,Socs7,Rhoq,Nod2,Flrt2,Serpine1,Fas,Nr3c1,Casp4,Gcnt2,Stat3,Src,Egr3,Stat2,Fpr2,Map2k1,Ass1,Hcls1,Ldlr,Sesn3,Ripk2,Serpina3f,Nos2,Il18,Akt3,Pid1,Nlrp3,Notch1,Crkl,Stat1,Timp1,Jak2,Tlr6,Flrt3,Inhba,Tlr2 |
| 5.362e-10 | -21.35 | regulation of T cell mediated immunity | biological process | GO:0002709 | 95 | 26 | 20694 | 1406 |
Rsad2,Il6,Traf2,Pvr,H2-Q6,Arid5a,Tnfsf4,Spn,H2-M2,Ifnb1,H2-T22,Nod2,H2-Q7,Tap2,H2-Q4,Ripk3,H2-T10,Il1b,Il12b,Nlrp3,Nectin2,H2-T24,Malt1,Tnfrsf1b,Fzd5,Il18 |
| 5.446e-10 | -21.33 | response to organic cyclic compound | biological process | GO:0014070 | 707 | 93 | 20694 | 1406 |
Il18,Zc3h12a,Tiparp,Gramd1a,Zc3hav1,Jak2,Stat1,Ddx58,Pim1,Inhba,Src,Stat3,Peli1,Nr3c1,Ass1,Idi1,Map2k1,Casp1,Ifna5,Pdgfb,Nos2,Ifna4,Ripk2,Mul1,Zfp36,Htr2a,Irak3,Nr1h3,Casp7,Homer1,Dnaja1,Ifih1,Fas,Nod2,Tlr9,Nfkbia,Slc9a1,Glrx,Ddit4,Nr4a1,Ifit3,Ezr,Il10,Ifna2,Atp2b4,Mecp2,Adora2a,Eif2ak2,Socs1,Stat5a,Ifna1,Cd83,Il1b,Casp3,Acod1,Ptch1,Itpr1,Htr2b,Tlr3,Usp18,Prkce,Nr4a3,Ahr,Nfkb1,Slc7a11,Cav1,Sell,Rapgef2,Ppp2r2a,Bmp2,Il6,Lox,Saa3,Cflar,Junb,Actb,Pde4b,Cgas,Il1rn,P2ry13,Hmgcs1,Larp1,Egr1,Ccl5,Ifnb1,Cdkn2d,Slc16a1,Ifna6,Ccl12,Daxx,Tnf,P2ry12,Jun |
| 5.647e-10 | -21.29 | DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS | MSigDB lists | DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS | 21 | 13 | 15632 | 1249 |
Sele,Il6,Ccl2,Edn1,Nos2,Ccl5,Tnf,Il1b,Kitl,Vcam1,Il18,Icam1,Ptgs2 |
| 5.652e-10 | -21.29 | purine ribonucleotide binding | molecular function | GO:0032555 | 1780 | 190 | 20217 | 1400 |
Nek6,Pcx,Mlkl,Dnaja1,Hk2,Rnd3,Map3k8,Hk3,Map2k1,Hspa1a,Pgk1,Nlrc4,Myo1b,Slfn5,Rnd1,Plk3,Prag1,Map3k6,Ikbke,Acvrl1,Pfkl,Arf4,Tlk2,Rab19,Gtpbp2,Ak4,Irak3,Mthfd1l,Abcc5,Ube2l6,Ehd1,Ciita,Clcn7,Cgas,Myo10,Ripk2,Clcn5,Atp10a,Oas2,Tyk2,Kdr,Trib3,Atm,Pik3cd,Hsph1,Swap70,Tgtp1,Gbp2b,Dck,Gbp9,Axl,Src,Hspa2,Arl5c,Gk,P2ry2,Igf1r,Slfn8,Fam20c,Sgk3,Irgq,Rap2c,Iigp1,Rras2,Mx1,Acvr1b,Atp2b4,Ptk2,Rac3,Irgm1,Dyrk2,Pikfyve,Cenpe,Ksr1,Oas3,Hcar2,Prkce,Lyn,Arl5b,Atp11a,Nod2,Chd9,Trip13,Abcb1a,Ddx4,Nlrc5,Dgka,Katna1,Dnaja2,Sik3,Atp13a1,Plk2,Tor3a,Rhof,Rab9,Pde5a,Ube2f,Papss2,Slfn9,Flt1,Smc5,Tuba4a,Stk40,Gmppb,Ddx58,Sphk1,Pim1,Map4k4,Nlrp3,Samhd1,Rhoc,Rab10,Pdk3,Prkar2b,Hspa1b,Scyl2,Akt3,Ube2e1,Acvr1,Oasl2,Irak2,Ascc3,Etnk1,Ift22,Mocs1,Rhoh,Gbp3,Helz2,Nod1,Gbp2,Tap1,Ass1,Vrk2,Hck,Acsl1,Tent2,Tap2,Dhx58,Nkiras1,Mcm9,Met,Map2k4,Rars,Asns,Jak2,Gbp8,Arl4a,Dync1h1,Pgs1,Fgr,Hk1,Ifih1,Eif2ak2,Rab20,Mcm6,Ripk3,Syk,Mov10,Acsl5,Pdgfrb,Mapkapk2,Prkx,Pim2,Kif3c,Rhou,Gem,Kif9,Gna15,Mark2,Wars,Pim3,Tent4a,Gch1,Gclc,Trib1,Apaf1,Grk3,Rab21,Cmpk2,Gbp7,Itpkc,Rhoq,Srxn1,Rab32,Actb,Ube2e2,Abcc1,Oasl1,Ep400,Pde4b |
| 5.696e-10 | -21.29 | regulation of NIK/NF-kappaB signaling | biological process | GO:1901222 | 102 | 27 | 20694 | 1406 |
Tlr9,Prdx1,Birc3,Glrx,Ago3,Traf2,Tnfsf15,Eif2ak2,Tnf,Irak2,Il18,Cd14,Zc3h12a,Malt1,Tlr1,Nlrp3,Il1b,Tlr3,Uaca,Sphk1,Ikbkg,Birc2,Edn1,Nod2,Nod1,Tlr2,Tnfsf14 |
| 5.835e-10 | -21.26 | regulation of interferon-gamma production | biological process | GO:0032649 | 109 | 28 | 20694 | 1406 |
Pde4b,Cd14,Il18,Fzd5,Zc3h12a,Axl,Irf8,Lgals9,Cd274,Isg15,Il1b,Il12b,Tlr3,Ifnar1,Il12rb1,Nod2,Ripk3,Il27,Tlr9,Prnp,Tnfsf9,Il10,Tnfsf4,Arid5a,Rasgrp1,Klrk1,Ripk2,Tnf |
| 5.866e-10 | -21.26 | macrophage activation | biological process | GO:0042116 | 47 | 18 | 20694 | 1406 |
Tlr6,Jak2,Tlr3,Syk,Cx3cl1,Tnf,Tlr2,Prkce,Jun,Jmjd6,Ifnb1,Slc7a2,Tlr9,Tlr1,Cx3cr1,Fpr2,Casp1,Nampt |
| 5.880e-10 | -21.25 | heterocyclic compound binding | molecular function | GO:1901363 | 4975 | 442 | 20217 | 1400 |
Pdk3,Rhoc,Ift57,Nr3c1,Ddx60,Ddx58,Junb,Gmppb,Pim1,Ifi213,Smc5,Nfil3,Stk40,Rbms2,Tuba4a,Ets2,Larp1,Ube2f,Irf2,Tlr9,Rhof,Nos2,Slc48a1,Atf3,Dr1,Bbx,Tor3a,Noct,Mtdh,Shfl,Hlx,Klf6,Oas1a,Vrk2,Tap1,Gbp2,Polr2g,Prdx1,Jarid2,Bcl6,Mocs1,Ift22,Gbp3,Fos,Rhoh,Rabgef1,Mycl,Pou2f2,Cpeb4,Ascc3,Ranbp2,Cycs,Ifi207,Hspa1b,Aim2,Ago3,Kif3c,Hivep2,Pdgfrb,Adar,Mapkapk2,Ripk3,Eno1,Rab20,N4bp1,Eif2ak2,Hdac1,Hk1,Dync1h1,Gbp8,Jak2,Cyfip1,Mthfr,Dhx58,Arid4a,Nkiras1,Lmo4,Acsl1,Ifit1bl2,Tlr3,Zfp945,Zfp319,Prdm9,Mecp2,Etv6,Srxn1,Tfec,Ankrd17,Sbds,Zbp1,Rhoq,Stat5a,Fubp1,Endod1,Itpkc,Rab21,Pml,Hinfp,Gclc,Apaf1,Pim3,Wars,Rel,Egr3,Klf7,Sp110,Ifi204,Prag1,Slfn5,Myo1b,Pgk1,Htr2a,Mcm10,Hspa1a,Egr1,Hk3,Ifi209,Hk2,Tal2,Nt5c3,Mndal,Klf3,Zfp40,Trib3,Kdr,Arid5b,Atp10a,Oas2,Ythdf1,Clcn5,Radx,Dach1,Myo10,Nr4a3,Eif4g2,Tiparp,Nfkb2,Txnrd1,Ehd1,Mthfd1l,Abcc5,Ak4,Cnp,Prpf4,Irak3,Hmga1,Gtpbp2,Tlk2,Zc3h7a,Hdc,Acvr1b,Ifit1bl1,Rras2,Stat2,Mx1,Zc3hav1,Rap2c,Adgb,Ahr,Lcn2,Zcchc2,Myc,Maff,Slfn8,Fam20c,Oas1b,Stat3,G3bp2,Hmox1,Mier3,Psip1,Axl,Dck,Rcan1,Cebpd,Tgtp1,Aff1,Dcp2,Mdm2,Hsph1,Atm,Prdm1,Mafk,Atp13a1,Igf2bp2,Cers6,Nr1h3,Gpsm2,Katna1,Dgka,Nod2,Ddx4,Spen,Arl5b,Lyn,Prkce,Max,Prdx5,Sp140,Phgdh,Ifit1,Sap30,Ikzf1,Ksr1,Ifi205,Ptk2,Ifit2,Irgm1,Dyrk2,Ahrr,Atp2b4,Rab10,Nlrp3,Rbm43,Map4k4,Samhd1,Sphk1,Klf8,Jun,Zfp36,Phf6,Csrnp1,Flt1,Papss2,Notch1,Slfn9,Foxp4,Trim21,Pde5a,Rab9,Tshz1,Lipe,Carhsp1,Zfp281,Parp14,Hopx,Nupr1,Trmt1l,Kmo,Ass1,Helz2,Jdp2,Nod1,Mxd1,Etnk1,Psma6,Ifi214,Zfp513,Kdm5b,Rbbp8,Batf,Setdb2,Nfxl1,Lhx2,Irak2,Acvr1,Oasl2,Stat4,Hif1a,Pcgf5,Scyl2,Ube2e1,Akt3,Prkar2b,Kif9,Mark2,Top3a,Gna15,Gem,Rhou,Pim2,Irf1,Mov10,Rfx5,Acsl5,Prkx,Syk,Tnf,Jmjd6,Mcm6,Ifih1,Pgs1,Fgr,Asns,Hmgn3,Arl4a,Casz1,Met,Map2k4,Rars,Pou3f1,Mcm9,Parp9,Xrn1,Tap2,Irf7,Tra2a,Hck,Sde2,Tent2,Tdrd7,Htr2b,Ep400,Dek,9130023H24Rik,Pde4b,Oasl1,Ube2e2,Abcc1,Hivep3,Actb,Taf4b,Cnot4,Rab32,Klf2,Plagl2,Irf8,Hmga2,Cmpk2,Zc3h12a,Ptgs2,Gbp7,Hhex,Tcf4,Grk3,Relb,Tet2,Irf4,Zhx2,Rbms1,Trib1,Snapc1,Plscr1,Marf1,Nxf1,Gch1,Tent4a,Acvrl1,Pfkl,Ikbke,Map3k6,Rbl1,Plk3,Rnd1,Nlrc4,Pnp2,Alas1,Apobec3,Znfx1,Kat2b,Timeless,Map2k1,Map3k8,Rnd3,Tcea1,Plagl1,Mlkl,Dnaja1,Dnase1l3,Nek6,Pcx,Arid5a,Mafg,Stau1,Sp100,H3f3b,Tyk2,Aebp2,Rbpms,Zeb1,Ripk2,Cgas,Trim30a,Clcn7,Ciita,Zup1,Ube2l6,Ifi208,Batf2,Ctu1,Isg20,Rab19,Tut7,Pnpt1,Magohb,Tnfaip3,Oas1g,Arf4,Iigp1,Irgq,Zfp800,Crlf3,Sgk3,P2ry2,Igf1r,Kdm6b,Gk,Arl5c,Etv3,Stat1,Src,Hspa2,Zbtb5,Gbp9,Gbp2b,Ifi211,Swap70,Fosb,Nfkb1,Pbx1,Pik3cd,Gsr,Dnaja2,Sik3,Nr4a1,Plk2,Nlrc5,Sirt1,Abcb1a,Ier2,Morc3,Chd9,Trip13,Atp11a,Me1,Smg7,Bcor,Rnf114,Spic,Oas3,Gfi1,Hcar2,Slpi,Denr,Cenpe,Sod2,Pikfyve,Rac3,Etv5,Ifi203,Rrs1,Egr2 |
| 5.936e-10 | -21.24 | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | MSigDB lists | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | 216 | 46 | 15632 | 1249 |
Cpeb4,Mmp9,C3,Pou2f2,Pstpip2,Gem,Birc3,Ccne1,Atp11b,Plau,Slc16a1,Ubash3b,Ccnd2,Nfkbiz,Chst11,Dock4,Hmga1,Bcl2a1b,Plaur,Stip1,Bcl2a1a,Nfkb2,Irak2,Serpinb2,Frmd4a,Spire1,St3gal1,Cd55,Scyl2,Pcgf5,Zc3h12a,Maff,Cxcl2,Phlda1,Slc7a2,Nampt,Gch1,Tnfaip3,Bmp2,Il1a,Sphk1,Prdm1,Bcl2a1d,Slc39a4,Dpy19l1,Slc16a3 |
| 5.977e-10 | -21.24 | GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_UP | MSigDB lists | GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_UP | 187 | 42 | 15632 | 1249 |
Rtn2,Plscr1,St3gal5,Ifi208,Ifi211,Rap1gap2,Ifi203,Map4k4,Rabgef1,Eno2,Ptch1,Mndal,Vezt,Pcdh7,Armc8,Cd200,Il13ra1,Gpr85,Ifi204,Rcan1,Rai14,Nat2,Irgq,B3gnt5,C1ra,Ifnar1,Ifi213,Klf3,Ifi205,Ifi209,Ttc39c,Cyfip1,Ube2f,Myd88,Col4a2,Extl2,Sgcb,Angpt1,Ifi207,Stxbp1,Ifi214,Tmtc2 |
| 5.977e-10 | -21.24 | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN | 187 | 42 | 15632 | 1249 |
Rbl1,Tnfaip3,Nod1,Xrn1,Traf1,Trim13,Ccl22,Phip,Ddx60,Gadd45g,B3gnt5,Top3a,Egr2,Micall2,Ankrd17,Homer1,Zswim4,Apobec3,Sec24b,Rgs1,Gca,Fam111a,Nr4a3,Chic2,Phf6,Dck,Oas1g,Filip1l,Dyrk2,Rhou,Parp12,Dcp1a,Dgka,Cd69,Oas1a,Rnf19a,Trim26,Sap30,Vps54,Ppp1r15a,Rnf14,Abtb2 |
| 6.014e-10 | -21.23 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | 527 | 84 | 15632 | 1249 |
Fndc3a,Oas1g,Hp,Lox,Arid5b,Ptgs2,Tnfsf10,Plat,Ralgds,Bambi,Pcdh7,Pilrb1,Snn,Glrx,Zhx2,Pgk1,Card6,Junb,Nampt,Pde4b,Slc7a2,Tnfsf15,Nrp2,Hk2,Arg2,Rnf135,Pigv,Gys1,Sav1,Tsku,Ncoa7,Dusp1,Bcl6,Otud1,Timp1,Cp,Rab9,Itgb8,Ccng2,Cebpd,Tapbp,Kdm5b,C3,Socs3,Azi2,Trib1,Tnfaip2,Col27a1,Nfil3,P4ha1,S100a8,Birc3,Eno2,C1rl,Lcn2,Plod2,Gna15,Slpi,Ksr1,Syne2,Egln3,Trim56,Oas1a,Nck1,Dtwd1,Papss2,Sdc1,Pgm1,Plagl1,Pilrb2,Ahr,Chmp4b,Rnf114,Ass1,Agrn,Bcl2l11,Sod2,Cited2,Ets2,Fos,Il6,Bnip3,Cpd,Tra2a |
| 6.039e-10 | -21.23 | positive regulation of inflammatory response | biological process | GO:0050729 | 138 | 32 | 20694 | 1406 |
Il6,Ptger4,Stat5a,Ptgs2,Tnf,Ccl3,Fcgr1,Tlr9,Nfkbia,Myd88,S100a8,Adora2b,Ctsc,Pla2g4a,Ldlr,Tnfsf4,Tlr3,Nfkbiz,Jak2,Stap1,Tlr6,Serpine1,Nod2,Tnip1,Osm,Tarm1,Nupr1,Ccl5,Tlr2,Pde5a,C3,Il1b |
| 6.091e-10 | -21.22 | GSE7852_LN_VS_FAT_TREG_DN | MSigDB lists | GSE7852_LN_VS_FAT_TREG_DN | 180 | 41 | 15632 | 1249 |
Zc3hav1,Tmtc2,Sgms2,Slco3a1,Carhsp1,Ets2,Dusp1,Sqstm1,Agpat4,Glrx,Prkar2b,Plcl2,Osbpl3,Bambi,Ralgds,Idi1,Dnajb4,Cxcl10,Rab20,Nr4a3,Mafg,Ier3,Dram1,Zc3h12a,Ell2,Il12rb1,Rapgef2,Rap1gap2,Syne2,Il18rap,Maff,Sap30,Flnb,Phlda1,Samsn1,Hopx,Fzd5,Rabgef1,Jdp2,Gch1,Brd2 |
| 6.091e-10 | -21.22 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_UP | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_UP | 180 | 41 | 15632 | 1249 |
Ppm1l,Ccnd2,Asap3,Nfkbil1,Plk3,Nfkbiz,Dusp14,Cd80,Tet2,Otud1,Dusp1,Psma6,Stk40,Cox17,Myc,Il6,Slc15a3,Rnf24,Dusp8,Il4i1,Stap1,Il12b,Slc43a3,Odc1,Socs3,Denr,Traf3ip2,Dtx2,Ebi3,Igf2bp2,Tnip1,Lad1,Il10,Ccl5,Eif4g2,Maff,Eef1e1,Leng9,Hivep3,Wdr59,Pstpip2 |
| 6.091e-10 | -21.22 | HOXA9_DN.V1_UP | MSigDB lists | HOXA9_DN.V1_UP | 180 | 41 | 15632 | 1249 |
Cd86,Plk2,Ascc3,Mndal,S100a8,Snx10,Gdf15,Map4k4,Bst1,Ifi203,Tdrd7,Parp12,Ifi211,Ifi208,Ms4a6d,Ifi204,Ptger4,Il13ra1,Fndc3a,Tfec,Zcchc2,Jak2,Arhgef3,Gpr18,Fos,Ifi205,Ifi209,Ifi213,Arhgap26,Vcan,Nod2,Fgl2,Ift57,Ifi214,Slc30a1,St3gal6,Isg15,Fas,Ifi207,Samhd1,Sgk3 |
| 6.091e-10 | -21.22 | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_DN | 180 | 41 | 15632 | 1249 |
Tlr2,Cxcl10,Irf1,Ptgs2,Ptges,Cdkn1a,Sp110,Il15ra,Tnfaip2,Nfkb2,Cflar,Casp4,Gch1,Ccl5,Cxcl2,Stat4,Jag1,Htra1,Zfp36,Psme2,Ube2l6,Sap30,Inpp5b,Isg20,Reps1,Kat2b,Aim2,Tnfaip3,Gbp2,Cd38,Stau1,Batf,Plau,Ptpn2,Psmb9,Fos,Dusp1,Tnf,Dusp4,Optn,Il6 |
| 6.144e-10 | -21.21 | cellular response to nitrogen compound | biological process | GO:1901699 | 574 | 80 | 20694 | 1406 |
Mdm2,Pdgfc,Il18,Sirt1,Zc3hav1,Trib3,Akt3,Nlrp3,Crkl,Tlr3,Itpr1,Stat1,Htr2b,Jak2,Casp3,Tlr6,Cav1,Nfkb1,Ddx58,Ahr,Nr4a3,Tlr2,Cdk5r1,Timeless,Thbs1,Rapgef2,Cpeb4,Casp4,Nmral1,Prnp,Stat3,Src,Fpr2,Cyfip1,Traf2,Mul1,Ripk2,Sesn3,Cflar,Pde4b,Itga4,Ptpn2,Actb,Ptk2,Cgas,Zeb1,Casp7,Socs7,Igf1r,Larp1,Ifih1,Phip,Rhoq,Vcam1,Kat2b,Nod2,Irs2,Ifnb1,Nod1,Rab10,Egr1,Icam1,Slc9a1,Tlr9,Adrb2,Agtrap,Irf1,Ezr,Nr4a1,Tnfsf4,Fcgr2b,Sh3bp4,Mecp2,Pde3b,Atp2b4,P2ry12,Stat5a,Socs1,Tnf,Daxx |
| 6.284e-10 | -21.19 | GO_REGULATION_OF_ERK1_AND_ERK2_CASCADE | MSigDB lists | GO_REGULATION_OF_ERK1_AND_ERK2_CASCADE | 209 | 45 | 15632 | 1249 |
Pdgfrb,Cav1,Ccl5,Dusp6,Ccr1,Rasgrp1,Rapgef2,Cysltr2,Pdgfb,Lyn,C3,Ripk2,Htr2b,Il1b,Gcnt2,Ccl4,Kdr,Tnip1,Jun,Ptpn2,Rgs14,Ccl12,Syk,Ezr,Tnf,Src,Dusp1,Nod2,Errfi1,Glipr2,Ccl2,Il6,Spry2,Cx3cl1,Cd74,Ccl22,Icam1,Lif,Atf3,Angpt1,Ccl3,Pdgfc,Bmp2,Htr2a,Nod1 |
| 6.591e-10 | -21.14 | response to oxidative stress | biological process | GO:0006979 | 332 | 55 | 20694 | 1406 |
Rgs14,Hp,Txnrd1,Axl,Zc3h12a,Sirt1,Mmp9,Hmox1,Nr4a3,Ripk3,Tnfaip3,Nfkb1,Slc7a11,Prdx5,Jak2,Casp3,Itgav,Sphk1,Uaca,Map2k1,Lcn2,Prnp,Src,Cd38,Thbs1,Ptgs2,Cflar,Fos,Traf2,Hif1a,Il6,1600014C10Rik,Kdm6b,Gclc,Rcan1,Pdgfrb,Nqo1,Gclm,Bnip3,Gsr,Nox1,Vrk2,Psip1,Etv5,Ppp1r15b,Abcc1,Pml,Hdac1,Prdx1,Plk3,Pnpt1,Sod2,Jun,Rbpms,Srxn1 |
| 6.731e-10 | -21.12 | MODULE_121 | MSigDB lists | MODULE_121 | 89 | 27 | 15632 | 1249 |
Cd86,Osm,Nampt,Csf3,Isg20,Zeb1,Csf1,Pdgfb,Il18,Il2rg,Cxcl10,Vegfc,Il15ra,Il1b,Tspan3,Timp1,Bcl6,Klf6,Edn1,Myc,Il6,Il1a,Cdk5r1,Mxd1,Lif,Prdx1,Il15 |
| 6.734e-10 | -21.12 | organic cyclic compound binding | molecular function | GO:0097159 | 5073 | 449 | 20217 | 1400 |
Gbp9,Gbp2b,Ifi211,Fosb,Swap70,Pbx1,Nfkb1,Pik3cd,Iigp1,Zfp800,Irgq,Sgk3,Crlf3,Igf1r,P2ry2,Kdm6b,Etv3,Stat1,Arl5c,Gk,Hspa2,Zbtb5,Src,Hcar2,Gfi1,Spic,Oas3,Sod2,Denr,Cenpe,Slpi,Pikfyve,Rac3,Etv5,Ifi203,Egr2,Rrs1,Plk2,Nr4a1,Dnaja2,Sik3,Gsr,Nlrc5,Sirt1,Abcb1a,Morc3,Ier2,Chd9,Trip13,Atp11a,Me1,Rnf114,Smg7,Bcor,Alas1,Pnp2,Znfx1,Apobec3,Kat2b,Map2k1,Timeless,Map3k8,Tcea1,Rnd3,Plagl1,Dnaja1,Dnase1l3,Mlkl,Arid5a,Pcx,Nek6,Pfkl,Acvrl1,Ikbke,Map3k6,Rbl1,Stard5,Plk3,Rnd1,Nlrc4,Zup1,Ciita,Ube2l6,Ifi208,Batf2,Magohb,Tnfaip3,Oas1g,Ctu1,Isg20,Rab19,Tut7,Pnpt1,Arf4,Mafg,Stau1,Sp100,H3f3b,Tyk2,Aebp2,Rbpms,Ripk2,Zeb1,Trim30a,Cgas,Clcn7,Pgs1,Fgr,Arl4a,Casz1,Hmgn3,Asns,Rars,Map2k4,Pou3f1,Met,Mcm9,Parp9,Xrn1,Tap2,Sde2,Tent2,Irf7,Tra2a,Hck,Mark2,Top3a,Gna15,Kif9,Gem,Rhou,Irf1,Pim2,Prkx,Acsl5,Rfx5,Mov10,Jmjd6,Syk,Tnf,Mcm6,Ifih1,Irf8,Hmga2,Ptgs2,Gbp7,Hhex,Tcf4,Cmpk2,Zc3h12a,Zhx2,Rbms1,Grk3,Relb,Irf4,Tet2,Trib1,Snapc1,Plscr1,Marf1,Nxf1,Gch1,Tent4a,Pde4b,Tdrd7,Htr2b,Ep400,9130023H24Rik,Dek,Oasl1,Adrb2,Abcc1,Ube2e2,Taf4b,Hivep3,Actb,Rab32,Gramd1a,Cnot4,Plagl2,Klf2,Notch1,Slfn9,Papss2,Trim21,Pde5a,Foxp4,Rab9,Tshz1,Lipe,Zfp281,Parp14,Carhsp1,Hopx,Rab10,Samhd1,Nlrp3,Rbm43,Map4k4,Klf8,Sphk1,Jun,Csrnp1,Phf6,Zfp36,Flt1,Batf,Setdb2,Rbbp8,Irak2,Nfxl1,Lhx2,Oasl2,Acvr1,Hif1a,Stat4,Ube2e1,Akt3,Pcgf5,Scyl2,Prkar2b,Nupr1,Trmt1l,Kmo,Ass1,Nod1,Helz2,Jdp2,Psma6,Mxd1,Etnk1,Zfp513,Ifi214,Kdm5b,Axl,Rcan1,Dck,Cebpd,Aff1,Tgtp1,Dcp2,Mdm2,Hsph1,Mafk,Atm,Prdm1,Ifit1bl1,Hdc,Acvr1b,Mx1,Stat2,Rras2,Rap2c,Adgb,Zc3hav1,Zcchc2,Lcn2,Ahr,Fam20c,Slfn8,Oas1b,Myc,Maff,G3bp2,Stat3,Hmox1,Psip1,Mier3,Ifit1,Sap30,Ikzf1,Ksr1,Ifi205,Ahrr,Ifit2,Irgm1,Dyrk2,Ptk2,Slc16a1,Atp2b4,Gpsm2,Nr1h3,Atp13a1,Igf2bp2,Cers6,Katna1,Dgka,Ddx4,Spen,Nod2,Max,Arl5b,Lyn,Prkce,Prdx5,Phgdh,Sp140,Htr2a,Mcm10,Hspa1a,Egr1,Hk3,Ifi209,Hk2,Tal2,Nt5c3,Mndal,Klf3,Klf7,Egr3,Sp110,Prag1,Ifi204,Slfn5,Tspo,Myo1b,Pgk1,Eif4g2,Tiparp,Nfkb2,Ehd1,Txnrd1,Abcc5,Mthfd1l,Irak3,Prpf4,Ak4,Cnp,Hmga1,Gtpbp2,Zc3h7a,Tlk2,Zfp40,Trib3,Kdr,Atp10a,Oas2,Arid5b,Ythdf1,Clcn5,Radx,Dach1,Myo10,Nr4a3,Hk1,Hdac1,Dync1h1,Osbpl3,Gbp8,Jak2,Cyfip1,Mthfr,Nkiras1,Dhx58,Arid4a,Lmo4,Acsl1,Ifit1bl2,Aim2,Kif3c,Ago3,Hivep2,Mapkapk2,Pdgfrb,Adar,Ripk3,N4bp1,Eno1,Rab20,Eif2ak2,Stat5a,Fubp1,Ankrd17,Sbds,Zbp1,Rhoq,Itpkc,Endod1,Rab21,Pml,Hinfp,Apaf1,Gclc,Rel,Pim3,Wars,Tlr3,Zfp945,Prdm9,Zfp319,Etv6,Mecp2,Tfec,Srxn1,Irf2,Tlr9,Ube2f,Rhof,Slc48a1,Nos2,Atf3,Dr1,Tor3a,Bbx,Noct,Shfl,Mtdh,Klf6,Hlx,Pdk3,Rhoc,Ift57,Ddx60,Nr3c1,Pim1,Ddx58,Gmppb,Junb,Stk40,Rbms2,Tuba4a,Ifi213,Smc5,Nfil3,Ets2,Larp1,Pou2f2,Cpeb4,Ascc3,Ranbp2,Cycs,Hspa1b,Ifi207,Oas1a,Vrk2,Tap1,Gbp2,Prdx1,Bcl6,Jarid2,Polr2g,Gbp3,Fos,Rhoh,Ptch1,Ift22,Mocs1,Rabgef1,Mycl |
| 6.760e-10 | -21.11 | BOSCO_TH1_CYTOTOXIC_MODULE | MSigDB lists | BOSCO_TH1_CYTOTOXIC_MODULE | 101 | 29 | 15632 | 1249 |
Cd38,Il15,Usp18,Rtp4,Socs1,Isg15,Ch25h,Ifnb1,Irf4,Abcb1a,Fcgr2b,Il4i1,Batf2,Gbp9,Gbp4,Rhbdf2,Il15ra,Cmpk2,Cd300e,Cmklr1,Adam19,Tmem229b,Itga9,Cxcl10,Smox,Herc6,Stat4,Il10,Rgl1 |
| 6.777e-10 | -21.11 | SCY | smart domains | SM00199 | 35 | 17 | 9567 | 823 |
Cxcl9,Cxcl3,Ccl3,Cxcl2,Cx3cl1,Ccl12,Ccl7,Ccl5,Pf4,Cxcl10,Ccl22,Ccl4,Ccl2,Cxcl1,Ccl8,Cxcl11,Ccl9 |
| 6.837e-10 | -21.10 | ribonucleotide binding | molecular function | GO:0032553 | 1796 | 191 | 20217 | 1400 |
Rac3,Dyrk2,Irgm1,Ptk2,Atp2b4,Hcar2,Ksr1,Oas3,Pikfyve,Cenpe,Dgka,Katna1,Nlrc5,Plk2,Dnaja2,Sik3,Atp13a1,Atp11a,Prkce,Lyn,Arl5b,Chd9,Trip13,Abcb1a,Ddx4,Nod2,Swap70,Atm,Pik3cd,Hsph1,Dck,Gbp9,Axl,Tgtp1,Gbp2b,P2ry2,Igf1r,Fam20c,Slfn8,Hspa2,Src,Arl5c,Gk,Mx1,Iigp1,Rras2,Acvr1b,Sgk3,Rap2c,Irgq,Irak3,Ak4,Abcc5,Mthfd1l,Arf4,Tlk2,Gtpbp2,Rab19,Ehd1,Ube2l6,Ciita,Ripk2,Clcn5,Clcn7,Myo10,Cgas,Trib3,Oas2,Tyk2,Atp10a,Kdr,Rnd3,Map3k8,Hk2,Pcx,Nek6,Dnaja1,Mlkl,Map2k1,Hk3,Hspa1a,Plk3,Prag1,Pgk1,Nlrc4,Myo1b,Slfn5,Rnd1,Pfkl,Acvrl1,Map3k6,Ikbke,Apaf1,Trib1,Gclc,Grk3,Gch1,Tent4a,Wars,Pim3,Itpkc,Rhoq,Rab21,Gbp7,Cmpk2,Actb,Rab32,Srxn1,Pde4b,Ep400,Abcc1,Ube2e2,Oasl1,Nkiras1,Dhx58,Mcm9,Tent2,Hck,Acsl1,Tap2,Dync1h1,Fgr,Pgs1,Hk1,Map2k4,Rars,Met,Jak2,Gbp8,Arl4a,Asns,Ripk3,Syk,Mapkapk2,Prkx,Pdgfrb,Acsl5,Mov10,Ifih1,Eif2ak2,Rab20,Mcm6,Gem,Gna15,Mark2,Kif9,Pim2,Rhou,Kif3c,Oasl2,Acvr1,Prkar2b,Hspa1b,Akt3,Ube2e1,Scyl2,Irak2,Ascc3,Etnk1,Rhoh,Gbp3,Ift22,Mocs1,Ass1,Tap1,Vrk2,Nod1,Helz2,Gbp2,Tor3a,Pde5a,Slfn9,Ube2f,Papss2,Nos2,Rab9,Rhof,Stk40,Tuba4a,Smc5,Flt1,Samhd1,Nlrp3,Map4k4,Rhoc,Rab10,Pdk3,Pim1,Gmppb,Ddx58,Sphk1 |
| 6.964e-10 | -21.09 | GO_REGULATION_OF_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_CELL_DIFFERENTIATION | 1372 | 172 | 15632 | 1249 |
Sema3c,Cav1,Casp8,Lmo4,Jdp2,Ednrb,Nfkb1,Mmd,Tmem176a,Rap1gap2,Csf1,Zeb1,Spen,Trib1,Lpar1,Lyn,Ptk2,Egr3,Sema4c,Rac3,Jak2,Ust,Ptpn2,Eif2ak2,Syk,Itgav,Ap3b1,Ifrd1,S1pr2,Ifnb1,Pde5a,Scarf1,Stap1,Mmp14,Katna1,Ubash3b,Kat2b,Cdk5r1,Mul1,Nr1h3,Cx3cl1,Tmem176b,Fas,Cd34,Il15,Il27,Tspo,Cd80,Gpc1,Flrt2,Hopx,Irf7,Map2k1,Ccr1,Dusp6,Myadm,Gja1,Gdf15,Ccl5,Vasn,Il12rb1,Inhba,Rapgef2,Fzd1,Pdlim7,Trib3,Il18,Tlr3,Ripk2,Il1b,Keap1,Kitl,Gcnt2,Ankrd17,Tcf4,Csf3r,Bcl6,Tnf,Phldb1,Mecp2,Glipr2,Errfi1,Hdac1,Gpr68,Rab21,Stat3,Cd74,Prdm1,Etv5,Sav1,Pbx1,Tnfsf14,Ptch1,P2ry2,Ccne1,Sirt1,Jag1,Rasgrp1,Acvr1b,Irf1,Sema4a,Mafg,Tnfsf4,Socs3,Stat1,Gfi1,Clcf1,Cflar,Fam20c,Hcls1,Kdr,Msr1,Fos,Jun,Nfkbia,Cx3cr1,Sdc2,4932438A13Rik,Cxcl14,Triobp,Irf4,Edn1,Spry2,Il6,Myc,Nlrp3,Il4ra,Lrp8,Mark2,Htr2a,Cd86,Plk2,Sipa1l1,Pik3r6,Junb,Nfkbid,Csf3,Hap1,Maff,Pdgfb,Scn1b,Ptgs2,Il12b,Cxcl10,Ptger4,Zc3h12a,Vegfc,Pf4,Zhx2,Cmklr1,Bambi,Prkx,Rgs14,P2ry12,Birc2,Ehd1,Axl,Lrp4,Acvr1,Ccnd1,Acvrl1,Pnp2,Hif1a,Sphk1,Isg15,Hlx,Pml,Lif,Daxx,Notch1,Cd83,Bmp2 |
| 7.029e-10 | -21.08 | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 573 | 89 | 15632 | 1249 |
Gadd45b,Dnaja1,Ptpn2,Dusp2,Dusp4,Nck1,Bcor,Cdkn2d,Kat2b,Ubash3b,Tspo,Spred1,Dusp14,Ppp1r15b,Cav1,Pid1,Trim21,Psme2,Trib1,Lyn,Dusp16,Dnajb2,Pmepa1,Cdkn1a,Tnf,Mecp2,Errfi1,Parp10,Psmb10,Rgs3,Irak3,Tnfaip3,Mvp,Dusp6,Myadm,Ppp1r15a,Flrt2,Ddit4,Psmb6,Trib3,Il1b,Ezr,Flrt3,Psmd10,Jun,Spry2,Myc,Il6,Prkce,Atf3,Prnp,Adar,Gclc,Atp2b4,Angpt1,Psmb8,Rabgef1,Sirt1,Socs3,Aida,Tnip1,Igf1r,Prkar2b,Socs7,Hsph1,Dusp1,N4bp1,Psmb9,Swap70,Rgs14,Hspa1a,Casp3,Cish,Dusp8,Psma6,Hhex,Ube2e1,Psme1,Lif,Pml,Kdm4a,Isg15,Socs1,Jarid2,Samsn1,Ptprj,Zc3h12a,Dusp5,Uchl1 |
| 7.065e-10 | -21.07 | GSE2706_R848_VS_LPS_8H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_LPS_8H_STIM_DC_DN | 153 | 37 | 15632 | 1249 |
Osm,Lad1,Map4k4,Dcun1d3,Snx10,Birc3,4930523C07Rik,Oas2,Il12rb1,Rnf19a,Nrp2,Ttc39b,Fndc3a,Ifi35,Tnfsf4,Tfec,Rap2c,Jak2,N4bp1,Gypc,Plekhf2,Slc25a37,Mecp2,Peli1,Rab9,Rab11fip1,Slco3a1,Gbe1,Tab2,Prrg4,Aim2,Ube2e1,Ddx60,Mvp,Cd80,Il15,Sdc4 |
| 7.065e-10 | -21.07 | GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_UP | 153 | 37 | 15632 | 1249 |
Whamm,Rgs1,Serpinb2,Zc3h12a,Usp42,Mmp25,Nr4a3,Cxcl10,Btg2,Zfp36,Rictor,Cd69,Dcp1a,Pde4b,Junb,Nampt,Jarid2,Plk2,Rel,Osm,Med21,Pim3,Zbtb5,Lipg,Tle3,Plk3,Atf3,Lif,Csrnp1,Hif1a,Etv3,Mafk,Nr4a1,Fos,Arid5a,Otud1,Tiparp |
| 7.279e-10 | -21.04 | GSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | 181 | 41 | 15632 | 1249 |
Ankib1,Slc4a7,Tuba4a,Lcp2,Rrs1,Lap3,Osm,Noc4l,G3bp2,Eef1e1,Etv6,Naa25,Usp31,Ppa1,Odc1,Spata5l1,Zcchc2,Ppp2r1b,Ldlr,Cd82,Slc37a3,Il15ra,Wdr43,Hsd17b7,Tnf,Srm,Irf4,D1Ertd622e,Myc,Mafk,Gadd45g,Dusp4,Plk3,Lrp8,Gmppb,Arl4a,Socs1,Pikfyve,Pim3,Spred1,Mdfic |
| 7.279e-10 | -21.04 | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B2_BCELL_DN | MSigDB lists | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B2_BCELL_DN | 181 | 41 | 15632 | 1249 |
Phlpp1,Ifrd1,Mlkl,Timp1,Ets2,Tiparp,Bcl2l11,Ifnar1,Trp53i11,Zbp1,Sphk1,Psme1,Tpi1,Lif,Mmd,Ccrl2,Maff,Tmeff1,Ext1,Slc7a5,Ifit3,Slc7a2,Eno2,Dusp6,Rcl1,Esd,Pgk1,Il1b,Ccl4,Irak2,Idi1,Slamf8,Kcna3,Arid5b,Ifit3b,Spire1,Tlr2,Herc6,Smox,Ldha,Uaca |
| 7.359e-10 | -21.03 | negative regulation of biosynthetic process | biological process | GO:0009890 | 1521 | 165 | 20694 | 1406 |
Pdgfb,Gbp4,Ifi208,Parp9,Znfx1,Src,Stat3,Nr3c1,Hcls1,Nmi,Nfkbie,Ifi203,Ccne1,Jarid2,Prdx5,Bcor,Errfi1,Foxp4,Klf8,Hat1,Sphk1,Cdyl2,Zc3h12a,Rnf139,Ifi211,Mndal,Notch1,Pid1,Gfi1,Plekhn1,Ets2,Hspa1a,Arid4a,Cenpj,Mecp2,Ptger4,Mov10,Atp2b4,Hopx,Slfn1,Eif2ak2,Tspo,Aebp2,Irf1,Hdac1,Dcp2,Pf4,Hinfp,Tnfsf4,Dach1,Ezr,Il10,Edn1,Xrn1,Spen,Klf2,Nsd3,Ptpn2,Cebpd,Zfp36,Myc,Zeb1,Etv6,Kdm5b,Tle3,Nr1h3,Dusp1,Hif1a,Nfil3,Il6,Kdm4a,Ahrr,Ifi213,Ciita,Sap30,Cflar,Nmral1,Cdyl,Plek,Dusp5,Rapgef2,Cpeb4,Cd38,Timeless,Mier3,Cd34,Bmp2,Adora2b,Rel,Zbtb5,Itgav,Ptch1,Gja1,Riox2,Ifi205,Sqstm1,Ifi209,Ahr,Ccnd1,Psmd10,Cdk5r1,Nr4a3,Cav1,Zmynd15,Klf7,Nfkb1,Relb,Klf3,Etv3,Sirt1,Acp5,Mdm2,Rfx5,Btg2,Il1b,Hhex,Hmga2,Trib3,Irf8,Gfpt1,Cited2,Plk3,Tnf,Daxx,Ifi204,Mdfic,Jun,Tcf4,Fzd1,Acvrl1,Mafk,Ikzf1,Met,Nck1,Zfp281,Mxd1,Prdm1,Arid5a,Ago3,Atf3,Phf6,Ifi207,Pml,Rbbp8,Dnajb4,Dr1,Eno1,Kmt5a,Mtdh,Rbl1,Larp1,Egr1,Zhx2,Notch2,Jdp2,Ppp1r15a,Ednrb,Junb,Bcl6,Max,Ifi214,Arid5b,Txn1,Gclc,Parp3 |
| 7.368e-10 | -21.03 | GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDC_UP | 174 | 40 | 15632 | 1249 |
Aebp2,Rai14,Spic,Arhgef3,Tnf,Gadd45b,Rab32,Prnp,Fam133b,Ccl22,Icam1,Isg15,P2ry14,Arg2,Fabp3,Traf1,Itga4,Evl,Sh3bp4,Degs2,Car13,Icosl,Ampd3,Nfkbib,Lcp2,Rel,Slc7a2,Igsf9,Rabgef1,Ppp1r15b,Lhx2,Cdkn1a,Znrf1,Plcl2,Dnajb4,Cdc42ep4,Acsl1,Gpr85,Mtmr14,Dtx2 |
| 7.393e-10 | -21.03 | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | MSigDB lists | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | 210 | 45 | 15632 | 1249 |
Agrn,Fos,Ets2,Vcan,Mid1,Atf3,Egr1,Phip,Zbtb5,Aff1,Cav1,Zfp36,Jag1,Sema4c,Itga5,Dyrk2,Mafg,Gfpt1,Rap2c,Cd82,Rgs1,Tcf4,Nr3c1,Rhoq,Egr2,Pnp2,Hhex,Pbx1,Etv5,Notch1,Myo10,Map4k4,Ppp1r15a,Myo1b,Ext1,Snx2,Larp1,Kdm6b,Dusp5,Ptgs2,Cdc42ep4,Mcm6,Ikbke,Sec24a,Dio2 |
| 7.481e-10 | -21.01 | negative regulation of peptide secretion | biological process | GO:0002792 | 162 | 35 | 20694 | 1406 |
Cx3cl1,Rhbdf2,Tnf,Mapkbp1,Rab11fip1,Rsad2,Arg2,Il6,Pde3b,Ptger4,Tnfsf4,Il10,Pml,Ezr,Angpt1,Hdac1,Map4k4,Cd34,Srgn,Cd200,Rabgef1,Frmd4a,Rgcc,Klf7,Tnfaip3,Tlr6,Pfkl,Il1b,Pim3,Nr1h3,Nlrp3,Lgals9,Cd74,Zc3h12a,Sirt1 |
| 7.594e-10 | -21.00 | UROSEVIC_RESPONSE_TO_IMIQUIMOD | MSigDB lists | UROSEVIC_RESPONSE_TO_IMIQUIMOD | 18 | 12 | 15632 | 1249 |
Ifi35,Oasl1,Stat1,Oas1g,Isg15,Trafd1,Irf7,Isg20,Il6,Oas1a,Rsad2,Oas2 |
| 7.913e-10 | -20.96 | HINATA_NFKB_TARGETS_FIBROBLAST_UP | MSigDB lists | HINATA_NFKB_TARGETS_FIBROBLAST_UP | 78 | 25 | 15632 | 1249 |
Sele,Il6,Mmp14,Birc2,Nfkbia,Sod2,Ccl12,Relb,Olr1,Tnfaip3,Rnd3,Cd83,Icam1,Cxcl2,Serpine1,Nfkb1,Gch1,Abcc1,Il1b,Nfkb2,Serpinb2,Sec24a,Tnfaip2,Irf1,Ier3 |
| 7.947e-10 | -20.95 | ZHAN_MULTIPLE_MYELOMA_LB_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_LB_DN | 33 | 16 | 15632 | 1249 |
Rsad2,Xaf1,Parp8,Dusp6,Zc3h12c,Casp4,Traf5,Ddx60,Ifi35,Stat1,Hif1a,Usp18,Irf1,Stat2,Rtp4,Psmb10 |
| 7.947e-10 | -20.95 | AMIT_EGF_RESPONSE_60_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_60_MCF10A | 33 | 16 | 15632 | 1249 |
Ier3,Trib1,Ptgs2,Zc3h12a,Egr1,Ptger4,Ier2,Tnfaip3,Klf7,Rnd3,Cxcl1,Jun,Plk2,Junb,Inhba,Il6 |
| 7.973e-10 | -20.95 | negative regulation of NF-kappaB transcription factor activity | biological process | GO:0032088 | 77 | 23 | 20694 | 1406 |
Acod1,Trim21,Nfkbib,Psmd10,Cd200,Nfkbid,Nod2,Tnfaip3,Sirt1,Zc3h12a,Irak3,Irak2,Nlrp3,Gfi1,Cmklr1,Nlrc5,Aim2,Peli1,Nfkbia,Tlr9,Nfkbil1,Tax1bp1,Parp10 |
| 7.980e-10 | -20.95 | GO_RESPONSE_TO_PEPTIDE | MSigDB lists | GO_RESPONSE_TO_PEPTIDE | 384 | 67 | 15632 | 1249 |
Igf1r,Prkar2b,Socs7,Gfpt1,Jak2,Lyn,Ptk2,Max,Socs3,Stat1,Jag1,Sirt1,Slc9a1,Cav1,Il10,Casp4,Nfkb1,Gng11,Pde3b,Kat2b,Phip,Irs2,Fas,Egr1,Nod2,Edn1,Il6,Ptpn2,Klf3,Nr4a1,Nfkbia,Ass1,Ccl12,Gng12,Il1b,Trib3,Nr4a3,Gng4,Ripk2,Fzd1,Rab10,Btg2,Pdgfb,Stxbp3,Klf2,Atp6v1d,Nampt,Junb,Ccl5,Gja1,Notch1,Tnfaip3,Gnb4,Nod1,Hif1a,Agtrap,Fabp3,Socs1,Mdm2,Errfi1,Stat3,Egr2,Rhoq,Timp1,Src,Klf6,Stat5a |
| 8.153e-10 | -20.93 | GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 196 | 43 | 15632 | 1249 |
Tlr6,Mapkapk2,Mul1,Cd74,Tab2,Bmp2,Htr2a,Nod1,Mdfic,Pdgfc,Daxx,Pik3r5,Syk,Src,Tnf,Flt1,Map3k6,Cd40,Traf2,Dbnl,Edn1,Pde5a,Nod2,S1pr2,Dusp5,Ripk2,Tlr9,Fpr1,Lpar1,Adora2b,Kitl,Irak2,Thbs1,Htr2b,Il1b,Ikbkg,Dusp6,Pik3r6,Map2k1,Pdgfrb,Fzd5,Pdgfb,Rasgrp1 |
| 8.157e-10 | -20.93 | NFKB_Q6_01 | MSigDB lists | NFKB_Q6_01 | 218 | 46 | 15632 | 1249 |
Dusp6,Ccl5,Arl5b,Tnfsf15,Nfkbid,Csf3,Ptprj,Gng4,Slamf8,Vcam1,Il1rn,Ralgds,Nfkb2,Ptges,5430427O19Rik,Cd40,Nr3c1,Zfp800,Icam1,Rnd1,Batf,Smg7,Relb,Birc3,Tnfrsf1b,Nfkbib,Cd69,Ebi3,Mtmr14,Uaca,Mmp9,Tnip3,Rbms1,Znrf1,Col27a1,Tnip1,Rap2c,Mob3c,Nfkbia,Gadd45b,Il4i1,Slc44a1,S1pr2,Rin2,Ifnb1,Il27 |
| 8.215e-10 | -20.92 | GRANDVAUX_IRF3_TARGETS_UP | MSigDB lists | GRANDVAUX_IRF3_TARGETS_UP | 15 | 11 | 15632 | 1249 |
Nr3c1,Ifi44,Oas2,Rsad2,Ifit2,Ifit1bl1,Ifit1bl2,Ifit3,Ifit3b,Arg2,Isg15 |
| 8.263e-10 | -20.91 | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN | 147 | 36 | 15632 | 1249 |
Dync1h1,H2-Q4,Tnf,Nlrc5,Dnaja1,Eno1,H2-Q6,Psmb9,Irf4,Parp14,H2-Q7,Gbp3,Cd74,Slc16a1,Gbp2,Rhoc,Samhd1,Psmb8,Txn1,Ascc3,Sipa1l1,Tap2,Psme2,Ube2l6,Trim26,Trim21,Wars,Il12rb1,Inhba,Stat1,H2-Ab1,Mmp25,Tmem229b,Irf1,Ap3m2,Trafd1 |
| 8.455e-10 | -20.89 | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP | 189 | 42 | 15632 | 1249 |
Rasgrp1,Trim21,Btg2,Gbp7,Klf2,Lcp2,Irf8,4930523C07Rik,Birc3,Pde4b,Gfi1,Epsti1,Inpp1,Znrf1,Mppe1,Filip1l,Ripk2,Egr3,Ptger4,Ifi35,Samd9l,Parp9,Tapbp,Stap1,Slc44a1,Pde1b,Egr2,Ikzf1,Parp14,Klf7,Aff1,Apaf1,Zbp1,Rtp4,Socs1,Pttg1,Usp18,Csrnp1,Cdkn2d,Marcksl1,Atf3,Lrch3 |
| 8.511e-10 | -20.88 | regulation of tyrosine phosphorylation of STAT protein | biological process | GO:0042509 | 71 | 22 | 20694 | 1406 |
Il6,Lif,Ptger4,Socs3,Parp9,Tnf,Socs1,Hdac1,Irf1,Parp14,Hcls1,Cd40,Jak2,Cav1,Lyn,Osm,Ccl5,Clcf1,Il15,Ptpn2,Il18,Il12b |
| 8.668e-10 | -20.87 | SAGIV_CD24_TARGETS_DN | MSigDB lists | SAGIV_CD24_TARGETS_DN | 42 | 18 | 15632 | 1249 |
Isg20,Pdgfb,Gem,Ppp1r15a,Cav1,Gdf15,Apobec3,Relb,Trafd1,Cdkn1a,Thbs1,Plau,Sphk1,Adrb2,Icam1,Oasl1,Dusp5,Atf3 |
| 8.668e-10 | -20.87 | GO_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS | MSigDB lists | GO_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS | 42 | 18 | 15632 | 1249 |
G3bp2,Nfkbib,Tnfsf14,Psmd10,Il10,Tnf,Nfkbia,Il1b,Prdx1,Il18,Nlrp3,Sphk1,Tlr2,Il12b,Ptgs2,Zc3h12a,Tlr3,Tlr9 |
| 8.685e-10 | -20.86 | GSE3982_DC_VS_MAC_LPS_STIM_DN | MSigDB lists | GSE3982_DC_VS_MAC_LPS_STIM_DN | 182 | 41 | 15632 | 1249 |
Gpr132,Htra1,Ifit3,Sik3,Abtb2,Ccnj,Rabgef1,Gng12,Il1b,Gcnt2,Ccl4,Adora2b,Clec5a,Cxcl10,Adrb2,Ifit3b,Rnf19b,Traf3ip2,Dusp5,Vcan,Tnc,Edn1,Stard5,Msr1,Ezr,Ifit2,Hivep2,Apobec3,Angpt1,Mcmbp,Zc3hav1,Gbp2,Pfkfb3,Fcgr1,Cd14,Slamf7,Stat2,Kmo,Ddx58,Papss2,Rnd1 |
| 8.685e-10 | -20.86 | GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | 182 | 41 | 15632 | 1249 |
Stat5a,Srm,Arid5a,Tspan3,Ankrd17,Bcl6,Eno1,Mdn1,Ikzf1,Stat3,Myc,Cish,Taf4b,Nfkbiz,Lrp8,Ubash3b,Hif1a,Socs1,Pfkfb3,Atp2b4,Notch1,Mthfd1l,Junb,Rrs1,Slc7a5,Slc39a14,Met,Larp1,Naa25,Ldha,Socs3,Pim2,Dyrk2,C3,Pim1,Arid5b,Znrf1,Sp110,Wdr43,Pgk1,Il1b |
| 8.685e-10 | -20.86 | GSE36527_CD62L_HIGH_CD69_NEG_VS_CD62L_LOW_CD69_POS_TREG_KLRG1_NEG_DN | MSigDB lists | GSE36527_CD62L_HIGH_CD69_NEG_VS_CD62L_LOW_CD69_POS_TREG_KLRG1_NEG_DN | 182 | 41 | 15632 | 1249 |
Parp9,Gadd45g,Parp14,Tnfsf8,Cish,Arid5a,D16Ertd472e,Rnf114,Txnrd1,Bcl2l11,Myd88,Batf,Hif1a,Slc39a13,Socs1,Il4ra,Mpp7,Plk3,Prdm1,Rhoh,Cdkn2d,Rnf19a,Vps54,Junb,Ccne1,Il15ra,Cdkn1a,Xcr1,Tnfaip2,Rgs1,Pim1,4930453N24Rik,Irf1,Cxcl10,Ttc39b,Rnf19b,Ifi35,Pim2,Ldha,Stat1,Socs3 |
| 8.829e-10 | -20.85 | GSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_DN | 175 | 40 | 15632 | 1249 |
Ier3,Map3k8,Slc31a1,Hmox1,Ell2,Ripk2,Frmd6,Hcar2,Cdkn1a,Ptges,Esd,Dusp16,Serpinb2,Jak2,Znrf1,Fscn1,Asns,Samsn1,Dach1,Eef1e1,Syne2,Flnb,Rab10,Srxn1,Zeb1,Gbp3,Palld,Ahr,Plagl2,Mdfic,Cd38,Notch1,Rnd3,N4bp1,Rab32,Psma6,Cpd,Mecp2,Slc44a1,Mmp14 |
| 8.980e-10 | -20.83 | negative regulation of transport | biological process | GO:0051051 | 538 | 76 | 20694 | 1406 |
Agrn,Txn1,Il1rn,Nr1h3,Cd74,Myc,Htr2a,Srgn,Rabgef1,Rgcc,Icam1,Irs2,Stxbp3,Edn1,Rhoq,Pfkl,Tnfsf4,Fcgr2b,Siglece,Il10,Pml,Ezr,Gpr35,Angpt1,Hdac1,Tlr9,Slc30a1,Cx3cl1,Tnf,Mapkbp1,Mdfic,Rab11fip1,P2ry12,Rsad2,Pde3b,Ptger4,Il1b,Pim3,Nlrp3,Notch1,Lgals9,Pid1,Zc3h12a,Ier3,Tnfrsf1b,Mmp9,Sirt1,Cd300lf,Cd200,Ahr,Frmd4a,Prkce,Hmox1,Tlr2,Klf7,Cav1,Tnfaip3,Osm,Itgav,Crbn,Tlr6,Gem,Stoml1,Thbs1,Map4k4,Cd34,Cacnb3,Gbp4,Rhbdf2,Ptgs2,Cnn2,Abr,Arg2,Il6,Cyfip1,Lif |
| 9.024e-10 | -20.83 | MODULE_2 | MSigDB lists | MODULE_2 | 352 | 63 | 15632 | 1249 |
Cd34,Gng11,Tnfrsf14,Me1,Ahr,Angpt1,Atf3,Ccnd2,Gbe1,Optn,Nr4a1,Ccl12,Fos,Tspan3,Ets2,Jun,Rgs1,Ldlr,Cdkn1a,Nfil3,Dnajb2,Kif5c,Cd200,Ier3,Acsl1,Zeb1,Fabp7,Cnn3,Slpi,Mmd,S100a8,Eno2,Tnfrsf1b,Ltbp2,Cav1,Gem,Lmo4,Crim1,Tnfaip3,Nupr1,Tnc,Rbpms,Ccnd1,Mtus1,Birc2,Bcl6,Gng12,H2-Ab1,Rtn1,Tgfbi,Ddit4,Ube2l6,H2-Aa,Csf3,Maff,Junb,Rgl1,Dusp6,Csrp1,Gdf15,Gja1,Ppp1r15a,Pdgfrb |
| 9.134e-10 | -20.81 | ubiquitin protein ligase binding | molecular function | GO:0031625 | 302 | 52 | 20217 | 1400 |
Sqstm1,Rffl,Traf5,Daxx,Casp8,Trib3,Kdm4a,Lyn,Caml,Trib1,Usp25,Hif1a,Ptk2,Traf2,Rnf34,Ubash3b,Egr2,Prkar2b,Hspa1b,Dnajb2,Fzd5,Dio2,Cd40,Ube2l6,Pml,Mul1,Sipa1l1,Rnf31,Tank,Syk,Myc,Mid1,Jun,Src,Cacybp,Nfkbia,H2-Ab1,Isg15,Tnfrsf1b,Traf1,Ddx58,Cdkn1a,Ikbke,Mdm2,Tpi1,Nek6,Tnfrsf14,Dnaja1,Triobp,Uchl1,Ikbkg,Hspa1a |
| 9.165e-10 | -20.81 | regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070302 | 237 | 44 | 20694 | 1406 |
Fzd5,Aida,Gadd45g,Il1rn,Gadd45b,Nox1,Edn1,Sema4c,Igf1r,Dnaja1,Fas,Nod2,Nod1,Myd88,Met,Phlpp1,Tlr9,Prdx1,Rasgrp1,Map2k4,Fcgr2b,Ezr,Syk,Tnf,Mapkbp1,Mdfic,Eif2ak2,Il1a,Zc3h12a,Mlkl,Il1b,Tlr6,Sphk1,Tlr3,Lyn,Map4k4,Hsph1,Bmp2,Map2k1,Traf2,Dusp1,Mid1,Mul1,Ripk2 |
| 9.168e-10 | -20.81 | LINDSTEDT_DENDRITIC_CELL_MATURATION_C | MSigDB lists | LINDSTEDT_DENDRITIC_CELL_MATURATION_C | 62 | 22 | 15632 | 1249 |
Il4ra,Cx3cl1,Plagl1,Atf3,Enpp4,Trip10,Arid5a,Stat5a,Ly75,Casp3,Stat3,Cd200,Tnfsf4,Nfil3,Trafd1,Prkar2b,Igf1r,Rgs1,Cd86,Lad1,Mmd,Zeb1 |
| 9.279e-10 | -20.80 | GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 436 | 73 | 15632 | 1249 |
Zc3hav1,Ahr,Atp2b4,Slc16a1,Adar,Plau,Il15,Nr1h3,Mul1,Lrp8,Egr1,Fas,Ifnb1,Il6,Edn1,Tiparp,Dnaja1,Msr1,Ccl12,Ass1,Nfkbia,Nr4a1,Ezr,Ifit1bl1,Pmepa1,Jak2,Stat1,Hmgcs1,Med13,Slc9a1,Ptch1,Casp8,P2ry2,Il10,Cav1,Ccne1,Rnf14,Nfkb1,Daxx,Bmp2,Hif1a,Errfi1,Acvr1,Mdm2,Stat3,Casp3,Nr3c1,Tnc,P2ry13,P2ry12,Src,Tnf,Klf6,Il1b,Htr2b,Keap1,Nr4a3,Serpinb9,Ptafr,Il18,Pim1,Ptgs2,Zc3h12a,Tlr3,Fzd1,Inhba,Rapgef2,Pdgfb,Klf2,Ppp1r15a,Ccl5,Ifit1bl2,Pde4b |
| 9.555e-10 | -20.77 | PI3K-Akt signaling pathway | KEGG pathways | mmu04151 | 341 | 66 | 7931 | 713 |
Angpt1,Phlpp2,Pdgfb,Akt3,Ppp2r2a,Nr4a1,Sgk3,Thbs1,Nfkb1,Ddit4,Ifna5,Itga5,Bcl2l11,Pik3r5,Ifnar1,Syk,Itgb8,Phlpp1,Gnb4,Igf1r,Csf3r,Mdm2,Col4a2,Flt1,Mtcp1,Il6,Ifna4,Pdgfrb,Osm,Csf1,Lpar1,Cdkn1a,Ppp2r5a,Map2k1,Itga9,Tlr2,Ptk2,Ifna1,Itgav,Pik3r6,Ccnd2,Ifna2,Tnc,Ccne1,Kdr,Il2rg,Gng12,Gng11,Pik3cd,Pdgfc,Ppp2r3a,Csf3,Ifnb1,Itga4,Kitl,Gng4,Ccnd1,Il4ra,Jak2,Ikbkg,Vegfc,Ifna6,Ppp2r1b,Myc,Gys1,Met |
| 9.555e-10 | -20.77 | PI3K-Akt signaling pathway | KEGG pathways | ko04151 | 341 | 66 | 7931 | 713 |
Bcl2l11,Ifnar1,Syk,Itgb8,Pik3r5,Itga5,Ifna5,Gnb4,Phlpp1,Ppp2r2a,Akt3,Pdgfb,Angpt1,Phlpp2,Thbs1,Ddit4,Nfkb1,Nr4a1,Sgk3,Osm,Pdgfrb,Il6,Ifna4,Map2k1,Itga9,Lpar1,Csf1,Ppp2r5a,Cdkn1a,Col4a2,Flt1,Mdm2,Igf1r,Csf3r,Mtcp1,Kdr,Il2rg,Ccne1,Gng11,Pik3cd,Gng12,Tlr2,Ptk2,Pik3r6,Ifna1,Itgav,Ifna2,Ccnd2,Tnc,Vegfc,Ccnd1,Jak2,Ikbkg,Il4ra,Myc,Met,Gys1,Ppp2r1b,Ifna6,Ppp2r3a,Csf3,Pdgfc,Kitl,Gng4,Ifnb1,Itga4 |
| 9.598e-10 | -20.76 | JACKSON_DNMT1_TARGETS_UP | MSigDB lists | JACKSON_DNMT1_TARGETS_UP | 73 | 24 | 15632 | 1249 |
Ccl12,Eif2ak2,Ifit1bl1,Hsph1,Hmga1,Ccng2,Isg15,Hif1a,Junb,Ifit1bl2,Irf7,Sema3c,Ifit3,Slpi,Zfp36,Phlda1,Csf1,Procr,Socs3,Cxcl10,Ifit3b,Ptgs2,Jak2,Cdkn1a |
| 9.612e-10 | -20.76 | tissue development | biological process | GO:0009888 | 1681 | 178 | 20694 | 1406 |
Atm,Ptgs2,Bcl9,Fos,Timeless,Slc39a13,Rapgef2,Rap2c,Ptch1,Htr2b,Tmeff1,Lmo4,F11r,Tagln,Myadm,Pbx1,Ahr,Chst11,Cav1,Csrp1,Fam20c,Hhex,Txnrd1,Gpsm2,Cited2,Il1a,Jun,Fzd1,Angpt1,Ikzf1,Prdm1,Atf3,Pml,Fgr,Ankrd17,Fndc3a,Igf1r,Icam1,Junb,Rpgrip1l,Col27a1,Sec24b,Arid5b,Pou3f1,Rilpl1,Mthfr,Lrp4,Hlx,Gsta3,Foxp4,Flnb,Tdrd7,Sbds,Tiparp,Sgcb,Notch1,Trip10,Gfi1,Mmp13,Ets2,Plau,Hdac1,Nr4a1,Acvr1,Intu,Plaur,Map2k4,Il10,Edn1,Homer1,Sema4c,Frmd6,Itga4,Sav1,Itgb8,Clic5,Hivep3,Mmp14,Itga5,Acvr1b,Hif1a,Il6,Phgdh,Lox,Jag1,Vasp,Sap30,Cflar,Thbs1,Nrp2,Lhx2,Bmp2,Sema4a,Itgav,Gja1,Casp3,Ccnd1,Nr4a3,Palld,Btg2,Mdm2,Hmga2,Egr2,Kdr,Sik3,Cacybp,Col11a2,Kitl,Acvrl1,Myd88,Met,Ift57,Arid5a,Pla2g4a,Sdc4,Cdkn1a,Casp8,Ext1,Vcam1,Tmem67,Clic4,Srgn,Egr1,Notch2,Ednrb,Slc4a7,Ifitm1,Plod3,Agrn,Kdm6b,Rcan1,Flt1,Arg2,Vcan,Slc25a25,Lif,Pdgfb,Psma6,Src,Sema3c,Nr3c1,Map2k1,4932438A13Rik,Snx10,Stat1,Jak2,Flrt3,Spint2,Errfi1,Maff,Inhba,Mthfd1l,Socs3,Arid4a,Tnc,Tulp3,Phactr4,Vegfc,Pdpn,Plagl1,Stat5a,Slc9a1,Apaf1,Ezr,Ntng2,Triobp,Ifrd1,Klf2,Csf1,Nupr1,Spry2,Col18a1,Pdgfrb,Fzd5,Myc,Prkx,Zeb1,Kdm5b |
| 9.640e-10 | -20.76 | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP | 197 | 43 | 15632 | 1249 |
Sat1,Peli1,Rin2,Vcan,H2-Q4,Dusp1,Nfkbia,Sod2,Sqstm1,H2-Q6,Csf3r,Pilra,Cd14,Klf7,Irak3,H2-Q7,Egr1,Prrg4,Upp1,Icam1,Slco3a1,Dmxl2,Btg2,Ext1,Snx2,Pla2g7,Bst1,S100a8,Nampt,Tnfrsf1b,Dusp6,Klf2,Marco,Sipa1l1,Cxcl1,Rbms1,Trem1,Glrx,Dram1,Hmox1,Ell2,Acsl1,Ier3 |
| 9.738e-10 | -20.75 | HIN_200 | prosite domains | PS50834 | 10 | 9 | 13278 | 1037 |
Ifi211,Ifi209,Ifi214,Ifi203,Aim2,Mndal,Ifi205,Ifi207,Ifi204 |
| 9.754e-10 | -20.75 | purine nucleotide binding | molecular function | GO:0017076 | 1792 | 190 | 20217 | 1400 |
Grk3,Apaf1,Gclc,Trib1,Tent4a,Gch1,Pim3,Wars,Rhoq,Itpkc,Gbp7,Cmpk2,Rab21,Actb,Rab32,Srxn1,Pde4b,Ep400,Oasl1,Abcc1,Ube2e2,Mcm9,Nkiras1,Dhx58,Tap2,Tent2,Acsl1,Hck,Hk1,Fgr,Pgs1,Dync1h1,Arl4a,Gbp8,Jak2,Asns,Rars,Map2k4,Met,Prkx,Mapkapk2,Pdgfrb,Mov10,Acsl5,Syk,Ripk3,Rab20,Mcm6,Eif2ak2,Ifih1,Mark2,Gna15,Kif9,Gem,Kif3c,Rhou,Pim2,Oasl2,Acvr1,Ube2e1,Akt3,Scyl2,Hspa1b,Prkar2b,Ascc3,Irak2,Gbp3,Rhoh,Mocs1,Ift22,Etnk1,Vrk2,Ass1,Tap1,Gbp2,Nod1,Helz2,Tor3a,Slfn9,Papss2,Ube2f,Pde5a,Rab9,Rhof,Stk40,Tuba4a,Smc5,Flt1,Pdk3,Rab10,Rhoc,Samhd1,Nlrp3,Map4k4,Pim1,Ddx58,Sphk1,Gmppb,Dyrk2,Irgm1,Rac3,Ptk2,Atp2b4,Hcar2,Oas3,Ksr1,Cenpe,Pikfyve,Plk2,Atp13a1,Sik3,Dnaja2,Katna1,Dgka,Nlrc5,Abcb1a,Ddx4,Trip13,Chd9,Nod2,Atp11a,Arl5b,Prkce,Lyn,Swap70,Hsph1,Pik3cd,Atm,Axl,Gbp9,Dck,Gbp2b,Tgtp1,Slfn8,Fam20c,Igf1r,P2ry2,Gk,Arl5c,Hspa2,Src,Acvr1b,Mx1,Rras2,Iigp1,Rap2c,Irgq,Sgk3,Abcc5,Mthfd1l,Irak3,Ak4,Gtpbp2,Rab19,Tlk2,Arf4,Ciita,Ehd1,Ube2l6,Clcn5,Ripk2,Myo10,Cgas,Clcn7,Trib3,Kdr,Oas2,Tyk2,Atp10a,Map3k8,Rnd3,Hk2,Dnaja1,Mlkl,Pcx,Nek6,Hspa1a,Map2k1,Hk3,Prag1,Plk3,Rnd1,Slfn5,Nlrc4,Myo1b,Pgk1,Pfkl,Acvrl1,Ikbke,Map3k6 |
| 9.860e-10 | -20.74 | negative regulation of apoptotic signaling pathway | biological process | GO:2001234 | 229 | 43 | 20694 | 1406 |
Icam1,Cdkn2d,Serpine1,Phip,Dnaja1,Gclc,Sgk3,Cd74,Gclm,Cx3cl1,Tnf,Rffl,Sod2,Bcl2a1b,Rnf34,Tnfsf4,Asah2,Plaur,Acvr1,Eya4,Cx3cr1,Pf4,Hdac1,Hmox1,Psmd10,Tnfaip3,Ikbkg,Itgav,Il1b,Grina,Sirt1,Mmp9,Ier3,Mdm2,Ptgs2,Cflar,Bcl2a1d,Hif1a,Higd1a,Map2k1,Src,Bcl2a1a,Hsph1 |
| 9.934e-10 | -20.73 | GO_POSITIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS | 57 | 21 | 15632 | 1249 |
Irf4,Tlr1,Cd86,Tnf,Spn,Syk,Il1b,Il27,Thbs1,Cd80,Tnfrsf8,Il1a,Irf1,Il12b,Ptafr,Tlr9,Ebi3,Tlr3,Mapkapk2,Tlr6,Hmox1 |
| 1.003e-09 | -20.72 | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN | 190 | 42 | 15632 | 1249 |
Tspan3,Cyfip1,Syk,Fgl2,Tbc1d1,Ctsc,Igsf6,Rhoq,Slc15a3,Ccl2,Kmo,Fgr,Papss2,Nr1h3,Nlrp3,Tmem176b,Palld,Pdgfc,Hk3,Hck,Plau,Pilra,Cd14,Cd86,S100a8,Slc31a2,Ccr1,Rgl1,Inhba,Tlr1,Slc2a6,Acvr1b,Slamf8,Acsl1,Ripk2,Rtn1,Hmox1,Ppfibp2,Tfec,Cdkn1a,Siglece,Slc29a3 |
| 1.008e-09 | -20.72 | positive regulation of vasculature development | biological process | GO:1904018 | 204 | 40 | 20694 | 1406 |
Mmp9,Sirt1,Zc3h12a,Ccr3,Hmga2,Notch1,Itgb8,Pik3r6,Il1b,C3,Akt3,Hk2,Tlr3,Cd40,Mtdh,Sphk1,Cysltr2,Hmox1,Ccl5,Egr1,Serpine1,Stat3,Acvrl1,Cd34,Thbs1,Plk2,Rapgef2,Il10,Cx3cr1,Itga5,Hif1a,Flt1,Kdr,Pdgfb,Vegfc,Il1a,Cx3cl1,Ptgs2,Cflar,Sod2 |
| 1.008e-09 | -20.72 | protein-containing complex binding | molecular function | GO:0044877 | 1236 | 142 | 20217 | 1400 |
Pim1,Micall2,Nr3c1,Isg15,Ifna4,Vcam1,Acvrl1,Itgav,Myo1b,Larp1,Lztfl1,Dbnl,Ifna1,Phf6,Ifna5,Casp3,Hcls1,Scarf1,Thbs1,Apba1,Ppp2r2a,Htr2a,Mlkl,Irs2,Tapbp,Tgfbi,Nes,Nod1,H3f3b,Kdr,Ccne1,Mmp9,H2-Q4,Plpp3,Casp8,Myo10,Psmb9,Pttg1,Ifnb1,Icam1,Ptch1,Ythdf1,Fscn1,Bcl2l11,Msr1,Cpeb4,Ciita,Fcgr1,Ldlr,Pdgfb,Fzd5,Hif1a,Syne2,Tlr2,Acvr1,Cdkn1a,Gpc1,Ahr,Antxr1,Whamm,Clic4,Gna15,Hsd17b12,Acvr1b,Itpr1,Ifih1,Src,Nfkbia,Rnf135,Itga9,Jmjd6,Fcgr2b,Igf1r,Syk,Cpd,Ifna2,Ripk3,Myc,Rictor,Met,Hmgn3,Prnp,Triobp,Mllt6,Tapbpl,Hdac1,Hk1,Fgr,Snx2,Pstpip2,Phip,Cdk5r1,Atm,Mdm2,Marcks,Rcsd1,Srgn,Itga5,Mcm9,Itgal,Mthfr,Fas,Fcgr4,Max,Lyn,Dync1i2,Adrb2,Tpm4,Carmil1,Cflar,Nod2,Katna1,H2-Q7,Ptpn2,Tagln,Sirt1,Gpsm2,Ezr,Plk2,S1pr2,Gnb4,Rab32,Itgb8,H2-Q6,Cav1,Lrp8,Cd74,Sipa1l1,Cx3cl1,Tulp3,Mmp14,Zc3h12a,Cenpe,Sbds,Tnks1bp1,Dnajb2,Mmp13,Il1b,Ifna6,Ccnd1,Ptk2,Traf2 |
| 1.009e-09 | -20.71 | GSE17974_0H_VS_0.5H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_0.5H_IN_VITRO_ACT_CD4_TCELL_DN | 148 | 36 | 15632 | 1249 |
Sesn3,Gja1,Gem,Arl5b,Fabp7,Btg2,Cd69,Nfkbid,Slc25a12,Slc31a1,Egr3,Nr4a3,Idi1,Bcl2a1a,5430427O19Rik,Tagap,Txnrd1,Bcl2a1b,Gadd45b,Nr4a1,Tnf,Dock4,Gpr18,Dusp2,Egr2,Dusp4,Bcl2a1d,Ifrd1,Bcor,Egr1,Ier2,Dtwd1,Slc30a1,Etv3,Pfkfb3,Prpf38a |
| 1.056e-09 | -20.67 | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN | 176 | 40 | 15632 | 1249 |
Cd86,Ccr1,Cxcl2,AA467197,Slamf9,Wars,Nrp2,Pstpip2,Tlr2,Lyn,Acsl1,Ptafr,Tgfbi,Il13ra1,Tfec,Lacc1,Fam20c,Clic4,Siglece,Actb,Msr1,Timp1,Dse,Slc25a37,Acvrl1,Vcan,Rin2,Igsf6,Kcnj2,Sat1,P2ry14,Dmxl2,Fpr2,Cyth3,Hck,Cd14,Plau,Pilra,Gnb4,Sgk3 |
| 1.063e-09 | -20.66 | regulation of interleukin-12 production | biological process | GO:0032655 | 54 | 19 | 20694 | 1406 |
Tlr9,Thbs1,Irak3,Acp5,Irf1,Tnfsf9,Irf8,Il10,Rel,Tnfsf4,Mefv,Il12b,Tlr3,Cd40,Cmklr1,Tlr6,Nod2,Nfkb1,Tlr2 |
| 1.071e-09 | -20.65 | GO_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 79 | 25 | 15632 | 1249 |
Prkce,Birc2,Tank,Nfkbia,Irak3,Cd14,Myd88,Tab2,Cd180,Mapkapk2,Tlr6,Tlr1,Irf7,Casp8,Cd86,Ikbkg,Birc3,Tnip1,Ikbke,Irak2,Tlr2,Tnip3,Ripk2,Tlr3,Tlr9 |
| 1.077e-09 | -20.65 | SWEET_LUNG_CANCER_KRAS_UP | MSigDB lists | SWEET_LUNG_CANCER_KRAS_UP | 446 | 74 | 15632 | 1249 |
Ctsc,Fcgr2b,Msr1,Cited2,Ppp1r14b,Me1,F10,Slc16a1,Prnp,Sdc1,Il4ra,Tpi1,Col18a1,Pla2g7,Slpi,Marco,Lap3,Lcn2,Hdc,Psat1,Pdk3,Hk1,Fam162a,Pfkl,Nfil3,Cdkn1a,Adam19,Ell2,Socs3,Errfi1,Ccnd1,Sat1,Ly75,Hspa1a,Tank,Hsph1,Axl,Ehd1,Clcn5,Relb,Mdfic,Cd14,Cd74,Atp11a,Hif1a,Arg2,Hhex,Itga4,Ch25h,Psme1,Bst1,Hk2,Vasp,Hap1,Phlda1,H2-Aa,Serpine1,Map2k1,Snx10,Gja1,Gch1,Dusp6,Pgk1,Glrx,Acsl5,Cldnd1,Thbs1,Tgfbi,Grina,Il18,St7,H2-Ab1,Ldha,Slc31a1 |
| 1.108e-09 | -20.62 | negative regulation of T cell activation | biological process | GO:0050868 | 119 | 29 | 20694 | 1406 |
Tarm1,Ifnb1,Nfkbid,Il4ra,Tnfrsf14,Casp3,Cd74,Lgals9,Cd274,Bcl6,Pde5a,Fgl2,Ptpn2,Zc3h12a,Hlx,Adora2a,Slfn1,Socs1,Cd80,H2-Aa,Arg2,Tnfsf4,Sdc4,Cd86,Spn,Irf1,Prnp,H2-Ab1,Peli1 |
| 1.138e-09 | -20.59 | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN | 198 | 43 | 15632 | 1249 |
Hk3,Tspo,Pilra,Dmxl2,Nlrp3,Cpd,Nod2,Rin2,Vcan,Igsf6,Kcnj2,Ets2,Cyfip1,Rab32,Tnfaip2,Actb,Asb13,Tlr2,Acvr1b,Itga5,Kctd12,Pstpip2,Adap2,P2ry2,Gna15,Marco,Tnfrsf1b,Hk1,St3gal6,Slco3a1,Upp1,Fgl2,Arhgap26,Sat1,Csf3r,Timp1,Plaur,Il1rn,Tgfbi,Hmox1,Hk2,Dusp6,Slc31a2 |
| 1.140e-09 | -20.59 | HUMMERICH_SKIN_CANCER_PROGRESSION_UP | MSigDB lists | HUMMERICH_SKIN_CANCER_PROGRESSION_UP | 85 | 26 | 15632 | 1249 |
Junb,Lcn2,Casp8,Mmp13,H2-Ab1,Hmox1,Mmp9,Itga5,Rcan1,Il1rn,Rbms1,Vcam1,Pgk1,Cdkn1a,Gadd45b,Sod2,Casp1,Fos,Eno1,Stat3,Myc,Mmp14,Col18a1,Il4ra,Socs1,Rhoc |
| 1.157e-09 | -20.58 | negative regulation of gene expression | biological process | GO:0010629 | 1709 | 180 | 20694 | 1406 |
Tent4a,Ddx4,Atm,Nfil3,Olr1,Ifi213,Ahrr,Mier3,Timeless,Cd38,Pik3cd,Dusp5,Helz2,Sqstm1,Ptch1,Klf7,Cav1,Myadm,Ifi209,Ahr,Sirt1,Etv3,Klf3,Irf8,Lgals9,Hhex,Cited2,Fzd1,Jun,Tcf4,Ifi204,Daxx,Tnf,Plk3,Prdm1,Mxd1,Noct,Ikzf1,Pml,Ccr1,Atf3,Parp10,Ago3,Larp1,Rbl1,Mtdh,Dr1,Msr1,Jdp2,Arid5b,Max,Junb,Gclc,Znfx1,Ifi208,Parp9,Gbp4,Nos2,Tut7,Jarid2,Ccne1,Ifi203,Nfkbie,Smg7,Ldlr,Klf8,Foxp4,Tiparp,Zc3h12a,Gfi1,Notch1,Mov10,Ets2,Hdac1,Irf1,Dach1,Tnfsf4,Hinfp,Tent2,Xrn1,Edn1,Serpine1,Nsd3,Zfp36,Ctla2a,Itgb8,Kdm4a,Acvr1b,Hif1a,Sap30,Ciita,Cd34,Thbs1,Cpeb4,Lhx2,Nmral1,Zbtb5,Rel,Bmp2,Ifi205,Gja1,Relb,Nfkb1,Zmynd15,Pcx,Keap1,Nr4a3,Psmd10,Cdk5r1,Ccnd1,Btg2,Mdm2,Rfx5,Polr2g,Trib3,Hmga2,Il1b,Kdr,Magohb,Mdfic,Zfp281,Nck1,Met,Acvrl1,Mafk,Ifi207,Cdkn1a,Phf6,Arid5a,Kmt5a,Eno1,Dnajb4,Notch2,Zhx2,Egr1,Ifi214,Bcl6,Ednrb,Ppp1r15a,Cst7,Txn1,Pdgfb,Nr3c1,Stat3,Src,Map2k1,Hcls1,Crkl,Hat1,Bcor,Prdx5,Adar,Ifi211,Rnf139,Mndal,Mecp2,Arid4a,Plekhn1,Aebp2,Pnpt1,Eif2ak2,Slfn1,Hopx,Dcp2,Gtpbp2,Ezr,Parp14,Birc3,Klf2,Spen,Birc2,Zc3h7a,Myc,Dcp1a,Cebpd,Ptpn2,Nr1h3,Zeb1,Etv6,Kdm5b |
| 1.190e-09 | -20.55 | regulation of CD4-positive, alpha-beta T cell activation | biological process | GO:2000514 | 66 | 21 | 20694 | 1406 |
Irf1,Il18,Malt1,Zc3h12a,Il27,Bcl6,Nlrp3,Cd83,Cd274,Tnfsf4,Lgals9,Arg2,Nfkbiz,Il6,Socs1,Nfkbid,Tarm1,Il4ra,Il2rg,Ripk2,Hlx |
| 1.200e-09 | -20.54 | CHASSOT_SKIN_WOUND | MSigDB lists | CHASSOT_SKIN_WOUND | 10 | 9 | 15632 | 1249 |
Rel,Klf2,Fos,Jun,Fosb,Junb,Egr3,Egr1,Egr2 |
| 1.205e-09 | -20.54 | PILON_KLF1_TARGETS_DN | MSigDB lists | PILON_KLF1_TARGETS_DN | 1807 | 213 | 15632 | 1249 |
Kpna3,Casp7,Dyrk2,Dck,Stat1,Fam111a,Pik3cd,Cflar,Socs7,Armc8,Psmb8,Psat1,Birc3,Irf8,Itgal,Ep400,Sirt1,Dcp1a,Hat1,Pgs1,Ccnd2,Dtwd1,Fcgr1,Vcpip1,Rab32,Igsf6,Tra2a,Dnaja2,Nsmaf,Acsl5,Gng12,Abcc4,Sec24b,Slc4a7,Jarid2,Tshz1,Cnp,Sipa1l1,Inpp5b,Noc4l,Marcksl1,Itga4,Cd180,Bfar,Smg7,Notch1,Cd164,Apobec3,Itpr1,Casp3,Fut8,Pnp2,Fchsd2,Mtdh,Rnf145,Notch2,Rbms1,Ppp2r1b,Abcc1,Wdr43,Rnf14,Cnn3,Alas1,Atxn7l1,Rap1gap2,Stx6,Il18rap,Coa5,Kat2b,Papss2,Cd34,Pilrb2,Tspo,Aff1,Hk3,Rbl1,Atp11b,Klf3,Morc3,Itgav,Ptpn2,Pla2g4a,Ctsc,Parp9,Hp,Pcgf5,Frmd4a,Mcm6,Cldnd1,Rcl1,Ccr1,Cdyl,Tor1aip1,Med21,Sap30,Reps1,H2-Aa,Snx2,Atp11a,Tab2,Psmb10,Myd88,Ube2f,Gda,Apaf1,Stat5a,Dpy19l1,Mtus1,Ankrd17,Csf3r,Ogfrl1,Aebp2,Ythdf1,Ebi3,Tmod3,Acvr1b,Aida,Sema4a,Gpd2,Acsl1,Cd300lf,Tmem123,Stard7,Igf1r,Ankib1,Gna15,Plekha2,Lcn2,Bcl9,Trip13,Timeless,Plscr1,Etv3,Nmral1,Trim13,Rras2,Pde3b,Samhd1,Cyfip1,Myc,Ppp2r5a,Kdm6b,Larp1,Tgfbi,Plcl2,Prkx,Caml,Nmi,Nfkbid,G3bp2,Magohb,Ube2e1,Hhex,Sell,Fgr,Dtx3l,Ripk3,Cst7,Plekhf2,Swap70,Nr3c1,Dennd1b,Setdb2,Top3a,Rffl,Gsr,Mppe1,Rcsd1,Fam102b,Rap2c,Vrk2,Nfkb1,Ikbkg,Sik3,Casp8,Lap3,Trim21,Ppp4r2,Kctd12,Etv6,Nck1,Extl2,Tle3,Plac8,Spn,Syk,D16Ertd472e,Fcgr2b,Cept1,Ifrd1,Naa25,Usp42,Il2rg,Pilrb1,Slc29a3,Inpp1,Ppp2r2a,Ttc9c,Brd2,Rrs1,Vps54,Fam133b,Sgk3,Sla,Klf6,D1Ertd622e,Cycs,Rab21,Phgdh,Treml2,Hdac1,Dock10,Cers6 |
| 1.206e-09 | -20.54 | GO_ADAPTIVE_IMMUNE_RESPONSE | MSigDB lists | GO_ADAPTIVE_IMMUNE_RESPONSE | 228 | 47 | 15632 | 1249 |
Bcl6,Swap70,Dbnl,Dennd1b,C1ra,Cd74,Icam1,Batf,Ifna2,Relb,H2-Eb1,Irf7,Tap2,Cd86,Ifna6,Icosl,Ripk2,Cd55,H2-Ab1,Rnf19b,Il18,Il12b,Clec4d,Nfkb2,Syk,Il6,Ctsc,Irf4,Ifnb1,Ifna5,Il18bp,Tlr6,Fas,Il4ra,Slamf7,Ifna1,Tap1,Clec4n,C1rl,Pou2f2,Jag1,C3,Ebi3,Pik3cd,Lyn,Sema4a,Jak2 |
| 1.218e-09 | -20.53 | apoptotic signaling pathway | biological process | GO:0097190 | 274 | 48 | 20694 | 1406 |
Ikbke,Bcl2a1d,Acvr1b,Ero1l,Atm,Casp1,Casp2,Lcn2,Plscr1,Bcl2a1a,Dyrk2,Bcl2l11,Ggct,Spn,Casp4,Hmox1,Cav1,Inhba,Jak2,Casp3,Itgav,Itpr1,Tlr3,Uaca,Il1b,Pmaip1,Trib3,Sirt1,Il18,Tnfrsf1b,Ier3,Daxx,Il1a,Ifi204,Tnf,Sod2,Jun,Kitl,Bcl2a1b,Ddit4,Casp8,Pml,Cdkn1a,Apaf1,Fas,Nupr1,Myc,Bnip3 |
| 1.230e-09 | -20.52 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_DN | 149 | 36 | 15632 | 1249 |
Ier2,Egr1,Bcor,Etv3,Pfkfb3,Prpf38a,Nr4a1,Tnf,Txnrd1,Bcl2a1b,Gpr18,Cycs,Dusp2,Egr2,Dusp4,Bcl2a1d,Egr3,Slc31a1,Dnajb4,Mthfd2,Nr4a3,Bcl2a1a,Vcam1,Snapc1,Tagap,Birc3,Sesn3,Med21,Gem,Btg2,Arl5b,Timeless,Tlr1,Phlda1,Nfkbid,Cd69 |
| 1.231e-09 | -20.52 | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_UP | MSigDB lists | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_UP | 184 | 41 | 15632 | 1249 |
Hivep3,Rapgef2,Il12rb1,Pdgfb,Lcp2,Itgal,Gem,Lmo4,Map4k4,Tuba4a,Glrx,Rbms1,Orai2,Cd82,Hcls1,Ppp2r1b,Tmem229b,4930453N24Rik,Rnf145,Irf1,Slc43a3,Sema4a,Dyrk2,Dusp2,Acpp,Mrpl52,Casp1,Bcl2l11,N4bp1,Notch1,Rgs3,Hvcn1,Slc28a2,Tle3,Myd88,Trp53i11,Rab19,Dcp2,Slco3a1,Psmb10,Abr |
| 1.231e-09 | -20.52 | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP | 184 | 41 | 15632 | 1249 |
Phlda1,Sap30,Ddit4,Gpr132,Btg2,Il12rb1,Mmd,Psd4,Jdp2,Card6,Pde4b,Klf2,Cnp,Tnip1,Gfi1,Glrx,Traf3ip2,Filip1l,Ptgir,Fam111a,Dnajb4,Parp11,Dusp2,Stard5,Gpr68,Ifnar1,Cited2,Rhof,Rgs14,Sla,Crlf3,Nod1,Traf5,Tnfaip3,Rgs3,Hvcn1,Rhoh,Mthfr,Irf2,Nck1,Rab19 |
| 1.231e-09 | -20.52 | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP | 184 | 41 | 15632 | 1249 |
Il2rg,Dusp5,C3,Keap1,Il1b,Cdkn1a,Mob3c,Tnip1,Serpinb2,Clcn7,Ubr4,Cd274,Hk2,AA467197,Pla2g7,Ccrl2,Trim56,Ampd3,Med13,Trim21,Sphk1,Kmo,Il1a,H2-Q7,Rhoc,Crim1,1600014C10Rik,Sav1,Sdc4,H2-Q6,Src,H2-Q4,Dync1h1,Hivep2,Scarf1,Mllt6,Ncoa5,Mecp2,Cish,Gpr35,Gclm |
| 1.234e-09 | -20.51 | positive regulation of defense response to virus by host | biological process | GO:0002230 | 29 | 14 | 20694 | 1406 |
Ccl5,Ddx58,Aim2,Parp9,Il12rb1,Stat1,Il12b,Cgas,Traf3ip2,Pml,Zc3h12a,Treml4,Dtx3l,Il27 |
| 1.261e-09 | -20.49 | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_UP | MSigDB lists | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_UP | 177 | 40 | 15632 | 1249 |
Csrnp1,Malt1,Aim2,Ier2,Aldh1b1,Nlrp3,Etv3,Rnd3,Ahr,Flrt3,Dusp1,Fos,Arid5a,Dusp2,Gadd45g,Zfp800,Filip1l,Socs3,Kdm6b,Adrb2,Ier3,Map3k8,Ptgs2,Irf1,Sec24a,Ccl4,Cxcl1,Cflar,Dr1,Il1b,Nfil3,Pde4b,Osm,Il10,Zfp36,Plscr1,Btg2,Cd69,Cxcl2,Met |
| 1.281e-09 | -20.48 | GSE6259_33D1_POS_DC_VS_CD4_TCELL_DN | MSigDB lists | GSE6259_33D1_POS_DC_VS_CD4_TCELL_DN | 163 | 38 | 15632 | 1249 |
Cpeb4,Acsl1,Fcho2,Fam20c,Ikbke,Vcam1,Cmklr1,Rgl1,Layn,Lcp2,Tlr1,Gbgt1,Rasgrp1,Tmem176a,Rhoh,Nupr1,Gbp3,Dmxl2,Irs2,Lpcat2,Tnfaip3,Olfml3,Slc28a2,Cd38,Hk3,Pdgfc,Etv5,Itgav,Dusp1,Aoah,Src,P2ry13,Csf3r,Arhgef3,P2ry12,Dse,Mtus1,Cp |
| 1.288e-09 | -20.47 | NFKB_Q6 | MSigDB lists | NFKB_Q6 | 236 | 48 | 15632 | 1249 |
Plau,Pde3b,Bcor,Il4i1,Mllt6,Rin2,Ifnb1,Nfkbia,Rap2c,Tnip1,Mob3c,Nlgn2,Tnfsf4,Ptgir,Uaca,Spen,Nfkbib,Rel,Lmo4,Cd83,Smg7,Rgs3,Prrg4,Icam1,Rnd1,Parp8,Cd40,Tank,Il1rn,Cxcl1,Vcam1,Nfkb2,Stip1,Zhx2,5430427O19Rik,Ptges,Ptprj,Xkr8,Ptgs2,Slamf8,Map3k8,Cxcl10,Tnfsf15,Nfkbid,Rgl1,Ccl5,Cd86,Samsn1 |
| 1.304e-09 | -20.46 | positive regulation of MAP kinase activity | biological process | GO:0043406 | 231 | 43 | 20694 | 1406 |
Il1rn,Gadd45b,Cd74,Pdgfrb,Fzd5,Pde5a,Gadd45g,Gdf15,Htr2a,Nod2,Edn1,Map3k6,Cd40,Rasgrp1,Map2k4,Met,Pik3r5,Tlr9,Mapkbp1,Tnf,Mdfic,Eif2ak2,Map3k8,Kitl,Syk,Pik3r6,Il1b,Pdgfc,Mlkl,Htr2b,Tlr6,Jak2,Crkl,Bmp2,Map2k1,Src,Thbs1,Mul1,Ripk2,Lpar1,Traf2,Flt1,Pdgfb |
| 1.311e-09 | -20.45 | cardiovascular system development | biological process | GO:0072358 | 573 | 79 | 20694 | 1406 |
Notch1,Hhex,Pik3r6,Prokr1,Il18,Sirt1,Zc3h12a,Tiparp,Sgcb,Mdm2,Hmox1,Ahr,Cav1,Errfi1,Cemip2,Gja1,Itgav,Crkl,Sphk1,Map2k1,Ptprj,Ldlr,Sema4a,Egr3,Nrp2,Sema3c,Thbs1,Rapgef2,Jag1,Lox,Ptgs2,Hif1a,Flt1,Lif,Spred1,Pdgfb,Ccr3,Tnfaip2,Itgb8,Prkx,Ptk2,Junb,Pdgfrb,Fzd5,Slc4a7,Sec24b,Egr1,Jmjd6,Notch2,Col18a1,Calcrl,Nox1,Wars,Edn1,Antxr1,Clic4,Ankrd17,Tnfsf4,Nr4a1,Acvr1,Ccl12,Casp8,Col4a2,Ccl2,Angpt1,Plau,Acvrl1,Prdm1,Cx3cl1,Pdpn,Jun,Socs3,Kdr,Cited2,Syk,Pde3b,Vegfc,Ptger4,Plpp3 |
| 1.342e-09 | -20.43 | GARY_CD5_TARGETS_UP | MSigDB lists | GARY_CD5_TARGETS_UP | 431 | 72 | 15632 | 1249 |
Bcl2a1d,Tbc1d1,Sat1,Phgdh,Tcf4,Slc25a37,Relb,Tnfaip3,Cd83,Fgr,Cd74,Icam1,Wars,Wdfy1,Btg2,Ddit4,Caml,Asns,Myadm,Junb,Plek,Pgk1,Nfkb2,Pilrb1,Bcl2a1a,Il2rg,Grina,Dusp5,Pcgf5,Cd55,Kdm6b,Ifrd1,Hmga1,Spic,Agrn,Bcl2a1b,Sqstm1,Bcl2l11,Slc7a11,Ppp1r14b,Gramd1a,Nfkbia,Tspo,Herc3,Pilrb2,Gbe1,Pou2f2,Cd69,Tifa,Rims3,Ogfr,Il10,P4ha1,Tor3a,Eno2,Psat1,Socs7,Cdkn1a,Fam162a,Esd,Pfkl,Tagap,Ccl4,Ldlr,Rgs1,Ust,Irf1,Stat1,Pim2,Uaca,Hmgcs1,Tlr9 |
| 1.365e-09 | -20.41 | GO_MEMBRANE_MICRODOMAIN | MSigDB lists | GO_MEMBRANE_MICRODOMAIN | 275 | 53 | 15632 | 1249 |
Icam1,Cd14,Hck,Tnf,Lipe,Src,Lrp4,P2ry12,Traf2,Slc2a1,Birc2,Casp3,Rhoq,Sele,Cd55,Hmox1,Kcna3,Ptgs2,Pgk1,Myadm,Gja1,Lcp2,Tlr1,Fas,Lrp8,Tlr6,Prnp,Pikfyve,Sdc4,Htr2a,Gpc1,Atp2b4,Spred1,Angpt1,Olr1,Ezr,Tlr2,Adrb2,Lyn,Cflar,Jak2,Ppp2r1b,Kdr,Prkar2b,Birc3,Ednrb,Hk1,Tnfrsf1b,Cav1,Casp8,Ptch1,Slc9a1,Plscr1 |
| 1.373e-09 | -20.41 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | 331 | 60 | 15632 | 1249 |
Myd88,Slc30a4,Prdm1,Mxd1,Upp1,Hif1a,Il1a,Cish,Carhsp1,Pnp2,Gpr68,Mafk,N4bp1,Ehd1,Klf6,P4ha2,Slc2a1,Elmod2,Pcdh7,Plaur,Slc31a1,Ldha,Ttc39b,Rcan1,Slc7a5,Rab10,Inhba,Card6,Tuba4a,Slc31a2,Lpcat2,Dusp14,Zc3hav1,Klf7,Rars,Arrdc4,Sgms2,Sdc1,Slc44a1,Pdpn,Stard5,Ezr,Arf4,Frmd6,Lrrc8c,Cdkn1a,Agpat4,Trem1,Ell2,Il13ra1,Cpeb4,Htra1,Alas1,Slc9a1,Egln3,Slamf9,Dcun1d3,S100a8,Casp4,Gna15 |
| 1.380e-09 | -20.40 | REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS | MSigDB lists | REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS | 43 | 18 | 15632 | 1249 |
Tab2,Nlrp3,Mefv,Aim2,Ripk2,Tnfaip3,Nod1,Irak2,Nlrc4,Casp8,Casp4,Birc2,Txn1,Birc3,Casp1,Ikbkg,Nod2,Casp2 |
| 1.392e-09 | -20.39 | regulation of interleukin-6 production | biological process | GO:0032675 | 150 | 33 | 20694 | 1406 |
Tnfsf4,Arid5a,Il10,Adora2b,Myd88,Stat3,Met,Tnfsf9,Tlr9,Il1a,Tnf,Ripk2,Ptafr,Il6,Tlr1,Il1b,Il1rn,Mapkapk2,Lgals9,Zc3h12a,Irak3,Tlr2,Ddx58,Trim30a,Cd200,Rabgef1,Nod2,Nod1,Tnfaip3,Tlr6,Tlr3,Klf2,Ifih1 |
| 1.440e-09 | -20.36 | GO_CELL_CHEMOTAXIS | MSigDB lists | GO_CELL_CHEMOTAXIS | 143 | 35 | 15632 | 1249 |
Pde4b,Ccr1,S100a8,Ccl5,Ednrb,Il10,Pdgfrb,Pdgfb,Cxcl2,Egr3,Lpar1,Itga9,Pik3cd,Cxcl10,Vcam1,Cxcl1,Ccl4,Trem1,Pf4,Il1b,Cx3cr1,Flt1,Nr4a1,Sbds,Syk,Ccl12,Csf3r,Dock4,Edn1,Ccl2,Il6,Cxcl14,Ccl22,Cx3cl1,Ccl3 |
| 1.492e-09 | -20.32 | regulation of myeloid cell differentiation | biological process | GO:0045637 | 215 | 41 | 20694 | 1406 |
Zfp36,Ptpn2,Myc,Isg15,Cnot4,Clec2d,Il12b,Cd74,Csf3r,Stat1,Fas,Csf1,Ccl5,Ifnb1,Notch2,Lyn,Trib1,Inhba,Ikzf1,Stat3,Csf3,Pilrb1,Nfkbia,Pf4,Gpr68,Hcls1,Casp8,Ccr1,Hif1a,Acvr1b,Ubash3b,Tmem178,Lif,Jag1,Lox,Ccl3,Tnf,Stat5a,Fos,Jun,Kitl |
| 1.497e-09 | -20.32 | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_DN | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_DN | 150 | 36 | 15632 | 1249 |
Fcgr2b,Ift57,S1pr2,Ncoa5,Insl6,Slc16a3,Ezr,Dnaja1,Homer1,Rgs14,Arid5a,Gng11,Rab3ip,Csrnp1,Nfkbil1,Kdm4a,Kmo,Med13,Phlpp2,Gpr132,Usp35,Jag1,Jdp2,Ttc9c,Abtb2,Sik3,Plekha2,Hcls1,Osbpl3,Dusp16,Esd,Ell2,Endod1,Fam53c,Arid5b,Ptgs2 |
| 1.503e-09 | -20.32 | positive regulation of cytokine-mediated signaling pathway | biological process | GO:0001961 | 44 | 17 | 20694 | 1406 |
Zbp1,Nlrc5,Traf2,Irf7,Parp9,Ripk2,Irgm2,Ikbke,Csf1,Cd300lf,Casp4,Irgm1,Casp1,Axl,Cd74,Parp14,Gfi1 |
| 1.504e-09 | -20.32 | GO_REGULATION_OF_T_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_T_CELL_DIFFERENTIATION | 98 | 28 | 15632 | 1249 |
Ptpn2,Bcl6,Syk,Ap3b1,Ifnb1,Irf4,Pnp2,Il6,Cd74,Nlrp3,Il4ra,Hlx,Cd83,Il15,Il27,Cd80,Cd86,Pik3r6,Nfkbid,Il12rb1,Rasgrp1,Zeb1,Irf1,Il12b,Egr3,Tnfsf4,Ripk2,Il1b |
| 1.504e-09 | -20.32 | GO_POSITIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | 98 | 28 | 15632 | 1249 |
Ptgs2,Adora2b,Tlr2,Il12b,Il18,Ptger4,Tnfsf4,Tlr3,Tlr9,C3,Il1b,Jak2,Ccl4,Tnip1,Osm,Serpine1,S100a8,Ccl5,Pla2g7,Cx3cl1,Ccl3,Il15,Tnf,Ccl12,Nod2,Pla2g4a,Il6,Ccl2 |
| 1.520e-09 | -20.30 | blood vessel development | biological process | GO:0001568 | 524 | 74 | 20694 | 1406 |
Sec24b,Junb,Pdgfrb,Fzd5,Ptk2,Ccr3,Tnfaip2,Itgb8,Prkx,Antxr1,Ankrd17,Clic4,Wars,Nox1,Edn1,Jmjd6,Calcrl,Notch2,Col18a1,Egr1,Prdm1,Angpt1,Ccl2,Plau,Col4a2,Acvrl1,Casp8,Tnfsf4,Nr4a1,Ccl12,Acvr1,Syk,Pde3b,Cited2,Vegfc,Ptger4,Plpp3,Socs3,Kdr,Jun,Cx3cl1,Tiparp,Mdm2,Il18,Sirt1,Zc3h12a,Prokr1,Notch1,Hhex,Pik3r6,Crkl,Sphk1,Cemip2,Gja1,Itgav,Cav1,Hmox1,Ahr,Nrp2,Thbs1,Sema3c,Rapgef2,Egr3,Sema4a,Map2k1,Ptprj,Ldlr,Spred1,Pdgfb,Hif1a,Flt1,Lox,Jag1,Ptgs2 |
| 1.530e-09 | -20.30 | GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 157 | 37 | 15632 | 1249 |
Dhrs9,Homer1,Cited2,Cd40,Csf3r,Gpr84,Fgl2,Cebpd,Dusp4,Stk40,Nfkbiz,Ier2,Agtrap,Tmc3,Lipg,Crim1,Ppfibp1,Dusp14,Ccl5,Il10,Mov10,Tnfsf14,Lmo4,Gpr132,Slc2a6,Nfkbid,Adora2a,Maff,Stx11,Hk2,Il18rap,Mmp9,Pim1,Kcna3,Clec4d,Map3k8,Pmepa1 |
| 1.531e-09 | -20.30 | GSE25087_TREG_VS_TCONV_ADULT_UP | MSigDB lists | GSE25087_TREG_VS_TCONV_ADULT_UP | 171 | 39 | 15632 | 1249 |
Abcc1,Cldnd1,Fcho2,Dusp5,Ell2,Rnf19a,Il12rb1,Slc7a5,Tifa,Map2k1,Casp8,Samsn1,Tnfrsf1b,Rbl1,Vcpip1,Ahr,Atp2b4,Slc16a1,Sdc4,Traf5,Mapkbp1,Irs2,Slco3a1,Tab2,Kat2b,B3gnt5,Optn,S1pr2,Fgl2,Rab11fip1,Ntng2,Irf4,Tiparp,Ttc39c,Cst7,Casp1,Sod2,Bcl2l11,Fam43a |
| 1.531e-09 | -20.30 | GSE25087_FETAL_VS_ADULT_TCONV_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TCONV_UP | 171 | 39 | 15632 | 1249 |
Trip13,Ppp4r2,Slc7a5,Tifa,Ccrl2,Il12rb1,Cxcl2,Dach1,Ahrr,Nfkb1,Plekhg1,Lmo4,Cxcl1,Orai2,Fscn1,Rgs1,Nfkb2,Stip1,Abcc1,Pgk1,Stat1,Rcn1,Il2rg,Ctsc,Dennd1b,S1pr2,Bcl2l11,Plekha5,Hmga1,Tiparp,Rbbp8,Prdx1,Lpcat2,Slc16a1,Cd38,Pdgfc,Clcn5,Prpf4,Psme1 |
| 1.531e-09 | -20.30 | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_UP | 171 | 39 | 15632 | 1249 |
Rgs1,Nfil3,Fam162a,Igf1r,Ldha,Cd200,Ripk2,Dusp5,Arl5c,Nr4a3,4930453N24Rik,Alas1,Spint2,Egln3,Slamf9,Jag1,Mmd,Dcun1d3,Hsd17b12,Cd86,Cd274,Hopx,Traf5,Mcoln2,Fas,Socs1,Traf1,Fabp3,Ccl22,Ly75,Ccl2,Cish,Acvrl1,Bcl2l11,Gramd1a,P4ha2,Cd40,Rhof,Trip10 |
| 1.543e-09 | -20.29 | Transcriptional misregulation in cancer | KEGG pathways | ko05202 | 174 | 42 | 7931 | 713 |
Hdac1,Aff1,Rel,Myc,Fcgr1,Met,Nupr1,Cdkn1a,Klf3,Hhex,Il6,Cd14,Hmga2,Nfkbiz,Birc3,Flt1,Plau,Mdm2,H3f3b,Bcl2a1b,Igf1r,Nr4a3,Pbx1,Dusp6,Pml,Plat,Cd86,Etv6,Bcl2a1d,Zeb1,Etv5,Traf1,Fut8,Mmp9,Atm,Ccnd2,Nfkb1,Bcl6,Ptk2,Cd40,Bcl2a1a,Max |
| 1.543e-09 | -20.29 | Transcriptional misregulation in cancer | KEGG pathways | mmu05202 | 174 | 42 | 7931 | 713 |
Atm,Ccnd2,Nfkb1,Bcl6,Ptk2,Bcl2a1a,Cd40,Max,Dusp6,Pbx1,Pml,Plat,Etv6,Bcl2a1d,Cd86,Etv5,Zeb1,Traf1,Fut8,Mmp9,Cd14,Hmga2,Nfkbiz,Birc3,Mdm2,Plau,Flt1,H3f3b,Bcl2a1b,Igf1r,Nr4a3,Rel,Myc,Hdac1,Aff1,Fcgr1,Nupr1,Met,Cdkn1a,Klf3,Il6,Hhex |
| 1.566e-09 | -20.27 | GO_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | 30 | 15 | 15632 | 1249 |
Ccl12,Ccl5,Nfkbia,Tnf,Prkce,Tlr2,Ptafr,Lyn,Il18,Ripk2,Mtdh,Il1b,Hck,Irak2,Cd14 |
| 1.566e-09 | -20.27 | WORSCHECH_TUMOR_EVASION_AND_TOLEROGENICITY_UP | MSigDB lists | WORSCHECH_TUMOR_EVASION_AND_TOLEROGENICITY_UP | 30 | 15 | 15632 | 1249 |
Ccl4,Cx3cl1,Il2rg,Il12b,Cxcl10,Il6,Il4i1,Ifrd1,Stat4,Ifnb1,Nfkb1,Ifnar1,Ccl12,Lcp2,Irf7 |
| 1.623e-09 | -20.24 | negative regulation of cytokine secretion | biological process | GO:0050710 | 67 | 21 | 20694 | 1406 |
Angpt1,Zc3h12a,Cd34,Tnfsf4,Nlrp3,Il10,Pml,Ezr,Lgals9,Arg2,Tlr6,Ptger4,Il6,Rgcc,Srgn,Cx3cl1,Cd200,Mapkbp1,Rabgef1,Tnf,Tnfaip3 |
| 1.623e-09 | -20.24 | Apoptosis | KEGG pathways | mmu04210 | 136 | 36 | 7931 | 713 |
Jun,Apaf1,Atm,Ctsc,Parp3,Gadd45b,Nfkb1,Akt3,Tnfsf10,Bcl2a1a,Casp8,Casp2,Bcl2a1d,Traf2,Pik3cd,Actb,Fas,Traf1,Birc2,Nfkbia,Daxx,Bcl2l11,Tnf,Tuba4a,Casp7,Pmaip1,Birc3,Casp3,Cycs,Fos,Bcl2a1b,Cflar,Map2k1,Gadd45g,Ikbkg,Itpr1 |
| 1.623e-09 | -20.24 | Apoptosis | KEGG pathways | ko04210 | 136 | 36 | 7931 | 713 |
Gadd45b,Nfkb1,Apaf1,Jun,Ctsc,Atm,Parp3,Bcl2a1a,Akt3,Tnfsf10,Pik3cd,Traf2,Casp8,Casp2,Bcl2a1d,Tnf,Tuba4a,Bcl2l11,Daxx,Nfkbia,Actb,Traf1,Fas,Birc2,Pmaip1,Birc3,Casp7,Bcl2a1b,Cflar,Fos,Cycs,Casp3,Map2k1,Itpr1,Ikbkg,Gadd45g |
| 1.689e-09 | -20.20 | MODULE_53 | MSigDB lists | MODULE_53 | 374 | 65 | 15632 | 1249 |
Trip13,Ppp4r2,Casp2,Cd69,Hat1,Eef1e1,Psmb8,S100a8,Eno2,Ikbkg,Gna15,Rgs1,Adam19,Hcls1,Ccl4,Pim2,Rac3,Mmp9,Ier3,Ctsc,Myc,Ifit1bl1,Slc7a11,Ccl12,Bcl2a1b,Fos,Ets2,Jun,Zyx,Plau,Tap1,Atf3,Pttg1,Ccnd2,Tpx2,Ddit4,Ube2l6,Slc7a5,H2-Aa,Hap1,Junb,Ifit1bl2,Ccl5,Asns,Serpine1,Fosb,Cxcl1,Bcl2a1a,Glrx,Dusp5,Mcm6,Il2rg,D1Ertd622e,Pnp2,Bcl2a1d,Tnf,Cst7,Swap70,Slc2a1,Sla,Hck,Mthfr,Lif,Fgr,Isg15 |
| 1.698e-09 | -20.19 | GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 758 | 108 | 15632 | 1249 |
Dusp6,Flrt2,Ppp1r15a,Serpine1,Sh3bp4,Spint2,Hp,Psmb6,Trib3,Il1b,Tnf,Ifi209,P2ry13,Errfi1,Prdx5,F11r,Psmb10,Rnf34,Rgs3,Tnfaip3,Mvp,Irak3,Ednrb,Nfkb1,Cav1,Casp8,Mndal,Ifi211,Cnn3,Slpi,Psme2,Tlr9,C3,Mmp9,Trib1,Ifi204,Lyn,Dusp16,Cdkn1a,Gadd45b,Ppp1r14b,Nlrc4,Ptpn2,Dnaja1,Dusp2,Dusp4,Nck1,Cdkn2d,Ubash3b,Kat2b,Irs2,Ifi214,Spred1,Ifi207,Dusp14,Ifit1bl2,Ifi208,Ptprj,Dusp5,Uchl1,Serpinb9,Thbs1,Serpinb2,Plaur,Dusp1,Ifi213,Src,Cst7,Rgs14,Psmb9,Timp1,Ifi205,Birc2,Casp3,Dusp8,Cish,Rffl,Mdm2,Psma6,Ube2e1,Psme1,Hhex,Rhoh,Pml,Socs1,Notch1,Crim1,Psmb8,Birc3,Tnfsf14,Sirt1,Ifi203,Socs3,Aida,Igf1r,Socs7,Gfi1,Prkar2b,Ifit1bl1,Flrt3,Psmd10,Spry2,Il6,Ppp2r5a,Nqo1,Pttg1,Adar,Atp2b4 |
| 1.733e-09 | -20.17 | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP | 186 | 41 | 15632 | 1249 |
Atf3,Atp11a,Icam1,Kdm4a,Batf,Slamf7,Klf7,Aff1,Tap1,Gbp2,Zc3hav1,Relb,Psmb9,D16Ertd472e,Phgdh,Gbp4,Gbp9,Ifrd1,Stk40,Ptger4,Filip1l,Fndc3a,Trib3,Irf1,Junb,Jdp2,Ppp1r15b,Asns,Lmo4,Gbp7,Vps54,Ddit4,Zfp36,Atxn7l1,Slc7a5,Trim56,Rasgrp1,Oas2,AA467197,Eef1e1,Maff |
| 1.790e-09 | -20.14 | GSE40443_INDUCED_VS_TOTAL_TREG_DN | MSigDB lists | GSE40443_INDUCED_VS_TOTAL_TREG_DN | 179 | 40 | 15632 | 1249 |
Ifit1bl2,Mthfd1l,Cnp,Psme2,Tlr1,Oas1a,Oas1g,Socs3,Traf3ip2,Pim2,Casp7,Mefv,Ms4a6d,Pim1,Rcn1,Slfn9,Cmpk2,Epsti1,Il15ra,Ifit1bl1,Dpy19l1,Klf3,Oas3,Psmb9,Dse,Myc,Ifi44,Peli1,Cish,Irgm2,Stat3,Slfn8,Psme1,Ifih1,Usp18,Nod1,Traf5,Myo10,Hvcn1,Tnfrsf14 |
| 1.820e-09 | -20.12 | GO_PHOSPHATE_CONTAINING_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_PHOSPHATE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 1805 | 212 | 15632 | 1249 |
Il15,Mul1,Irs2,Pgm1,Nck1,Pde5a,Dusp4,Phlpp1,Cept1,Sqstm1,Syk,Eif2ak2,Vrk2,Dusp16,Jak2,Lyn,Mppe1,Trib1,Ptk2,Mmd,Psme2,Sik3,Hk1,Ikbkg,Nfkb1,Ppp1r15b,Atm,Lipg,Sgk3,Upp1,Tlk2,Cycs,Ddhd1,Tnf,Dusp28,Ppp2r2a,Acp2,Inpp1,Irak2,Il2rg,Trib3,Crkl,Tlr3,Pde7b,Rapgef2,Il12rb1,Eya4,Phlpp2,Ppp1r15a,Ccl5,Dusp6,Pde4b,Plek,Samhd1,Mark2,Pde3b,Ppm1l,Sgms2,Mapkapk2,Myc,Slc44a1,Pik3r5,Ccl12,Igf1r,Kdr,Fam20c,Gpd2,Tlr2,Acvr1b,Itpkc,Etnk1,Smpdl3b,Plscr1,Eno2,Pdk3,Ripk3,Daxx,Bmp2,Nod1,Sphk1,Fgr,Pml,Psme1,Acvrl1,Acvr1,Rhoq,Pde1b,Dbnl,Eno1,Psmb9,Lipe,Axl,Dusp1,Cmpk2,Prkx,Pim1,Scyl2,Dusp5,Ptprj,Hk2,Dgka,Tyk2,Pik3r6,Cd86,Map4k4,Gch1,Me1,Dusp14,Hk3,Spred1,Cd80,Lpcat2,Pim3,Papss2,Pikfyve,Cdk5r1,Ubash3b,Tpi1,Nek6,Dusp2,Pla2g4a,Ptpn2,Itgav,Morc3,Idi1,Gfpt1,Map2k4,Pim2,Tlr9,Dgkh,Rictor,Cav1,Irak3,Gda,Pigv,Psmb10,Tab2,Kmo,Plk3,Prdx5,Mecp2,Stat3,Stat5a,Pgk1,Il1b,Htr2b,Ikbke,Kitl,Il18,Map3k8,Adora2b,Psmb6,Ripk2,St3gal1,Ppp2r3a,Pdgfrb,Map2k1,Osm,Angpt1,Slc25a25,Ciita,Pfkfb3,Pgs1,Nod2,Prkce,Psmd10,Flt1,Map3k6,Pfkl,Agpat4,Pik3cd,Ppa1,Dck,Dyrk2,Mtmr14,Nox1,Met,Rasgrp1,Oas1a,Ampd3,Akt3,Ksr1,Ccne1,Psmb8,Hck,Mdfic,Calcrl,Lif,Psma6,Mlkl,Stk40,Ccnd1,Dusp8,Pnp2,Minpp1,Hspa1a,Acpp,Src,Plaur,Ptafr,Ak4,Ldha,Oas1g,Ptger4,Oas2,Adora2a,Pdgfb,Inpp5b,Ppm1k,Cnp,Plk2,Nampt |
| 1.831e-09 | -20.12 | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN | 172 | 39 | 15632 | 1249 |
Cd86,S100a8,Ccr1,Slc31a2,Plek,Rgl1,Tmem176a,Tlr1,Slc2a6,St3gal5,Ms4a6d,Tgfbi,Rab20,Lyn,Ripk2,Rtn1,Cdkn1a,Acp2,Fscn1,Mgat1,Cd302,Bcl6,Ccl12,Plod3,Sqstm1,Fcgr2b,Tbc1d1,Igsf6,Ly75,Rhoq,Ccl22,Kmo,Il4ra,Dmxl2,Ddx60,Hlx,Pdgfc,Hck,Cd83 |
| 1.837e-09 | -20.11 | KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY | 64 | 22 | 15632 | 1249 |
Ikbke,Azi2,Cxcl10,Il12b,Nfkbib,Ifna6,Nfkb1,Ikbkg,Casp8,Irf7,Ifna1,Ifna2,Ifih1,Isg15,Ddx58,Dhx58,Ifna5,Ifnb1,Tnf,Nfkbia,Tank,Traf2 |
| 1.858e-09 | -20.10 | FARMER_BREAST_CANCER_CLUSTER_1 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_1 | 39 | 17 | 15632 | 1249 |
Ifi44,Oas2,Rsad2,Xaf1,Oas1a,Ifit1bl2,Ifit1bl1,Oas3,Lcp2,Ifit3,Gpr18,Cd38,Oasl1,Oas1g,Herc6,Ifit3b,Isg15 |
| 1.911e-09 | -20.08 | MODULE_537 | MSigDB lists | MODULE_537 | 19 | 12 | 15632 | 1249 |
Bnip3,Bcl2a1d,Nfkb1,Bcl2a1b,Birc3,Birc2,Serpinb2,Bcl2a1a,Cflar,Tnfaip3,Ier3,Il1a |
| 1.916e-09 | -20.07 | regulation of cell killing | biological process | GO:0031341 | 129 | 30 | 20694 | 1406 |
Lgals9,Cd55,Il12b,Clec2d,Pik3r6,Tap1,Nectin2,Dnase1l3,H2-T24,H2-T22,Serpinb9,Ripk3,H2-Q4,H2-Q7,Tap2,Stap1,H2-T10,Pvr,H60b,H2-Q6,Rasgrp1,Il18rap,H2-M2,Ccl2,Bcl2l11,Cxcl1,Stat5a,Nos2,Raet1e,Klrk1 |
| 1.939e-09 | -20.06 | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | 99 | 28 | 15632 | 1249 |
Ccl4,Kitl,Thbs1,Cmklr1,Cxcl1,Pf4,Il1b,Vegfc,Ptger4,Ptafr,Cxcl10,Csf1,Cxcl2,Pla2g7,Ccl5,Ccr1,Serpine1,Tnfsf14,Tnfrsf14,Itga4,Cx3cl1,Cd74,Icam1,Il6,Cxcl14,Ccl12,Tnf,Swap70 |
| 1.954e-09 | -20.05 | HELLER_HDAC_TARGETS_DN | MSigDB lists | HELLER_HDAC_TARGETS_DN | 262 | 51 | 15632 | 1249 |
Ccnd1,Dock10,Serp1,Tcf4,Hspa1a,Hsph1,Phf11b,Apobec3,Pbx1,Sla,Cd180,St3gal6,Psmb10,Aim2,Ube2e1,Magohb,Rhoh,Maff,Slc7a5,Ppp1r15a,Rrs1,Ccr1,Gja1,Dusp6,Zhx2,Trib3,Il2rg,St7,Tapbpl,Nsmaf,Larp1,Hmox1,Ctsc,Myc,Slc7a11,Olr1,Ppfibp1,Phf11c,Phf11a,Sdc1,Ccnd2,Cdk5r1,Fas,Atf3,Lrp8,Isg20,Psat1,Eif4g2,Cflar,Phf11d,Dnajb4 |
| 1.993e-09 | -20.03 | negative regulation of protein secretion | biological process | GO:0050709 | 152 | 33 | 20694 | 1406 |
Angpt1,Map4k4,Hdac1,Cd34,Tnfsf4,Ezr,Il10,Pml,Arg2,Il6,Ptger4,Pde3b,Mapkbp1,Tnf,Cx3cl1,Rhbdf2,Rab11fip1,Rsad2,Zc3h12a,Il1b,Nlrp3,Nr1h3,Pim3,Lgals9,Tlr6,Pfkl,Rabgef1,Cd200,Srgn,Rgcc,Frmd4a,Tnfaip3,Klf7 |
| 1.994e-09 | -20.03 | GO_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS | MSigDB lists | GO_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS | 87 | 26 | 15632 | 1249 |
Nfkbie,Psmd10,Tnf,Nfkbia,Prdx1,Ddx58,Sphk1,Nlrp3,Nfkbil1,G3bp2,Csf3,Slc9a1,Nfkbib,Tnfsf14,Il10,Keap1,Il1b,Hcls1,Ptgs2,Il18,Il12b,Tlr2,Tlr9,Tlr3,Zc3h12a,Dyrk2 |
| 1.994e-09 | -20.03 | BROWNE_HCMV_INFECTION_12HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_12HR_UP | 93 | 27 | 15632 | 1249 |
Trim21,Plscr1,Oas2,Xaf1,Stx11,Mfap3l,Rel,Asns,Ldlr,Stip1,Rnf19b,Pim2,Tlr2,Gpd2,Map2k4,Mmp14,Ccdc86,Ifi44,Ifrd1,Phactr4,Homer1,Zbtb5,Bmp2,Tap1,Plagl2,Tle3,Pml |
| 2.008e-09 | -20.03 | GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | MSigDB lists | GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | 603 | 91 | 15632 | 1249 |
Htr2a,Chmp4b,Tnfrsf14,Tap1,Ccr3,Nfkbia,Cx3cr1,H2-Q4,Ifit1bl1,Ccl12,Bcl2l11,Jun,Zyx,Cflar,Tnip1,Kdr,Trem1,Gfi1,Kpna3,Stat1,Fam111a,Sirt1,Psmb8,Ubr4,Daxx,Mdfic,Hck,H2-Q7,Pml,Ddx58,Kdm4a,Icam1,Stat2,Trim12c,Isg15,Rab9,Ccdc86,Mdm2,Src,Axl,Psmb9,Hspa1a,Dek,Cd55,Zc3h12a,Clec5a,Serpinb9,Caml,Ifit1bl2,Cd86,Pilra,Cd80,Zc3hav1,Rbl1,Kat2b,Nxf1,Fcgr2b,Bnip3,Pcx,Eif2ak2,Morc3,Syk,Itgav,Psip1,Hmga1,Ccl4,Ldlr,Vrk2,Itga5,Lyn,Spen,Ikbkg,Cav1,Casp8,F11r,Ifih1,Psmb10,Stat3,Hdac1,Dhx58,Rsad2,H2-Q6,Ankrd17,Vcam1,Mitd1,Sp110,Psmb6,Il2rg,Ccl5,Tap2,Irf7 |
| 2.038e-09 | -20.01 | negative regulation of cellular biosynthetic process | biological process | GO:0031327 | 1483 | 160 | 20694 | 1406 |
Mndal,Notch1,Pid1,Gfi1,Zc3h12a,Rnf139,Ifi211,Bcor,Prdx5,Foxp4,Klf8,Errfi1,Cdyl2,Sphk1,Hat1,Hcls1,Nmi,Nfkbie,Ccne1,Ifi203,Jarid2,Stat3,Src,Nr3c1,Gbp4,Parp9,Ifi208,Znfx1,Pdgfb,Etv6,Kdm5b,Zeb1,Nr1h3,Tle3,Cebpd,Ptpn2,Zfp36,Myc,Nsd3,Edn1,Xrn1,Spen,Klf2,Hinfp,Tnfsf4,Dach1,Il10,Ezr,Irf1,Hdac1,Dcp2,Hopx,Slfn1,Eif2ak2,Aebp2,Tspo,Hspa1a,Plekhn1,Ets2,Arid4a,Cenpj,Mecp2,Atp2b4,Mov10,Il1b,Hmga2,Hhex,Trib3,Irf8,Klf3,Etv3,Acp5,Sirt1,Btg2,Mdm2,Rfx5,Ccnd1,Ahr,Ifi209,Nr4a3,Psmd10,Cdk5r1,Klf7,Zmynd15,Cav1,Relb,Nfkb1,Gja1,Ptch1,Riox2,Sqstm1,Ifi205,Bmp2,Rel,Zbtb5,Nmral1,Plek,Cdyl,Dusp5,Cd38,Timeless,Cpeb4,Rapgef2,Cd34,Mier3,Ahrr,Ifi213,Ciita,Sap30,Hif1a,Dusp1,Il6,Nfil3,Kdm4a,Txn1,Gclc,Parp3,Ednrb,Ppp1r15a,Junb,Max,Bcl6,Arid5b,Ifi214,Egr1,Zhx2,Notch2,Jdp2,Dnajb4,Eno1,Dr1,Mtdh,Kmt5a,Larp1,Rbl1,Ago3,Arid5a,Ifi207,Phf6,Atf3,Pml,Rbbp8,Mafk,Acvrl1,Ikzf1,Met,Mxd1,Nck1,Zfp281,Prdm1,Tnf,Plk3,Mdfic,Ifi204,Daxx,Tcf4,Jun,Fzd1,Gfpt1,Cited2 |
| 2.042e-09 | -20.01 | DAPIN | prosite domains | PS50824 | 23 | 13 | 13278 | 1037 |
Ifi208,Ifi204,Mefv,Ifi205,Ifi207,Ifi213,Aim2,Mndal,Nlrp3,Ifi209,Ifi203,Ifi214,Ifi211 |
| 2.049e-09 | -20.01 | cellular response to interleukin-1 | biological process | GO:0071347 | 74 | 22 | 20694 | 1406 |
Il6,Ccl4,Saa3,Cx3cl1,Ccl3,Il1a,Ccl7,Irf1,Tank,Ccl2,Ccl12,Acod1,Serpine1,Nfkb1,Egr1,Ccl5,Irak3,Ccl8,Irak2,Ccl22,Zc3h12a,Ccl9 |
| 2.052e-09 | -20.00 | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_DN | 187 | 41 | 15632 | 1249 |
Filip1l,Rab20,Frmd4a,Ttc39b,Acsl1,Rap2c,Zcchc2,Notch2,Arf4,Agpat4,Lnpep,S100a8,Birc3,Snx10,Rims3,Casp8,Vps54,Itgal,Lcp2,Fabp7,Ext1,Pstpip2,Syne2,Mmd,Dmxl2,Icam1,Ccnd2,Il1a,Cdc42ep2,Slc16a1,Myd88,Nod1,Herc3,Olr1,Tle3,Syk,Stat5a,Ly75,Stard5,Samd9l,Aebp2 |
| 2.059e-09 | -20.00 | negative regulation of DNA-binding transcription factor activity | biological process | GO:0043433 | 160 | 34 | 20694 | 1406 |
Trib1,Tnfaip3,Nod2,Nfkbid,Pim1,Nupr1,Pbx1,Cd200,Keap1,Hmox1,Psmd10,Nfkbib,Igf1r,Trim21,Acod1,Ptch1,Gfi1,Nlrp3,Med13,Irak2,Irak3,Zc3h12a,Sirt1,Aim2,Nlrc5,Cmklr1,Tnfsf4,Parp10,Tax1bp1,Nfkbil1,Tlr9,Nfkbia,Peli1,Prnp |
| 2.162e-09 | -19.95 | PID_TNF_PATHWAY | MSigDB lists | PID_TNF_PATHWAY | 44 | 18 | 15632 | 1249 |
Tab2,Traf1,Nsmaf,Stat1,Tnfaip3,Cav1,Traf2,Birc2,Casp8,Birc3,Tnf,Txn1,Map4k4,Nfkb1,Ikbkg,Sqstm1,Tnfrsf1b,Rffl |
| 2.170e-09 | -19.95 | positive regulation of CD4-positive, alpha-beta T cell differentiation | biological process | GO:0043372 | 30 | 14 | 20694 | 1406 |
Malt1,Il18,Irf1,Nlrp3,Tnfsf4,Cd83,Il6,Nfkbiz,Socs1,Hlx,Ripk2,Nfkbid,Il4ra,Il2rg |
| 2.182e-09 | -19.94 | GO_LYMPHOCYTE_DIFFERENTIATION | MSigDB lists | GO_LYMPHOCYTE_DIFFERENTIATION | 202 | 43 | 15632 | 1249 |
Ifna2,Relb,Ripk3,Clec4e,Il15,Batf,Ifna1,Jmjd6,Cd74,Rhoh,Egr1,Malt1,Itga4,Fas,Hhex,Ifnb1,Ifna5,Rsad2,Tnfsf8,Il6,Irf4,Ikzf1,Ptpn2,Bcl6,Syk,Axl,Klf6,Spn,Plcl2,Vcam1,Clcf1,Notch2,Sema4a,Il12b,Clec4d,Pik3cd,Irf1,Ptger4,Pou2f2,Ifna6,Il10,Fzd5,Atm |
| 2.185e-09 | -19.94 | GSE2585_CTEC_VS_MTEC_THYMUS_UP | MSigDB lists | GSE2585_CTEC_VS_MTEC_THYMUS_UP | 173 | 39 | 15632 | 1249 |
Nupr1,Ch25h,Agtrap,Fcgr1,Cd14,Pilrb2,Rhoc,Aoah,Trip10,Arid5a,Cyfip1,Slc15a3,Scarf1,Mmp9,Mtdh,Ebi3,Hp,Rab20,Fpr1,Ak4,Bambi,Cxcl1,Pilrb1,Dcbld2,Fam162a,Gja1,S100a8,Dach1,Map2k1,Osm,Serpine1,Tnfsf14,Antxr1,Slpi,Ddit4,Cnn3,Leng9,Hk2,Ccrl2 |
| 2.199e-09 | -19.94 | positive regulation of alpha-beta T cell activation | biological process | GO:0046635 | 68 | 21 | 20694 | 1406 |
Il12b,Tnfsf4,Cd83,Nlrp3,H2-Ab1,Malt1,Irf1,Il18,Ikzf1,Hsph1,Ap3b1,Socs1,Ripk2,Hlx,Il4ra,Il2rg,Nfkbid,Il6,Nfkbiz,Syk,Cd80 |
| 2.200e-09 | -19.93 | negative regulation of secretion | biological process | GO:0051048 | 261 | 46 | 20694 | 1406 |
Ezr,Pml,Il10,Tnfsf4,Slc30a1,Hdac1,Angpt1,Rsad2,Rab11fip1,P2ry12,Mapkbp1,Tnf,Cx3cl1,Ptger4,Pde3b,Cd74,Nr1h3,Il1rn,Rgcc,Rabgef1,Srgn,Pfkl,Edn1,Stxbp3,Cd34,Map4k4,Abr,Rhbdf2,Lif,Il6,Arg2,Lgals9,Nlrp3,Notch1,Pim3,Il1b,Sirt1,Tnfrsf1b,Zc3h12a,Osm,Tnfaip3,Klf7,Hmox1,Frmd4a,Cd200,Tlr6 |
| 2.216e-09 | -19.93 | GO_RESPONSE_TO_OXIDATIVE_STRESS | MSigDB lists | GO_RESPONSE_TO_OXIDATIVE_STRESS | 335 | 60 | 15632 | 1249 |
Tnfaip3,Cd38,Etv5,Stau1,Pml,Plk3,Sphk1,Hif1a,Cycs,Casp3,Gsr,Prdx5,Mdm2,Txnrd1,Dusp1,Klf6,Src,Hspa1a,Rgs14,Traf2,Il1b,Zc3h12a,Ldha,Hmox1,Kdm6b,Hp,Nr4a3,Ptgs2,Ccl5,Txn1,Pdgfrb,Klf2,Gclc,Pnpt1,Prdx1,Olr1,Fas,Sdc1,Kat2b,Prnp,Mmp14,Il6,Pla2g4a,Edn1,Bnip3,Gclm,Nqo1,Il18bp,Slc7a11,Sod2,Psip1,Jun,Fos,Jak2,Vrk2,Srxn1,Il18rap,Sirt1,Ppp1r15b,Nfkb1 |
| 2.225e-09 | -19.92 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_DN | 159 | 37 | 15632 | 1249 |
Pfkfb3,Tle3,Samhd1,Mdfic,Lif,Fas,Malt1,P2ry14,Znrf3,Gbp3,Cyth3,Il1a,Lrch1,Kcnj2,Ccl12,Ifit2,Jun,Otud1,Itpr1,Tnfsf10,Gca,Il1b,Abcc4,Lacc1,Dusp16,Tnfsf4,Atp10a,Gpd2,Ifit3b,Ptgs2,Tifa,Plscr1,Ddit4,Stx11,Hap1,Med21,Ifit3 |
| 2.225e-09 | -19.92 | GSE4590_SMALL_VS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_SMALL_VS_LARGE_PRE_BCELL_UP | 159 | 37 | 15632 | 1249 |
Pla2g4a,Slc15a3,Cpd,Slc25a37,Gadd45b,Plac8,Ankrd17,Rnd3,Clec4e,Cd38,Hck,Slc28a2,Tlr6,Cd180,Nrp2,Tmem26,Pla2g7,Vasp,Eif4g2,S100a8,Dusp6,Sesn3,Zc3h12c,Cd274,Plk2,Cxcl1,Slc29a3,Ptger4,Arl5c,Ptprj,Tlr3,Dusp5,Rnf145,Clec4d,Ptafr,Il18,Ier3 |
| 2.255e-09 | -19.91 | regulation of stress-activated MAPK cascade | biological process | GO:0032872 | 235 | 43 | 20694 | 1406 |
Eif2ak2,Il1a,Mdfic,Tnf,Mapkbp1,Syk,Ezr,Fcgr2b,Map2k4,Rasgrp1,Prdx1,Tlr9,Phlpp1,Met,Myd88,Nod1,Nod2,Fas,Dnaja1,Igf1r,Sema4c,Edn1,Nox1,Gadd45b,Il1rn,Aida,Gadd45g,Fzd5,Ripk2,Mul1,Mid1,Dusp1,Traf2,Map2k1,Bmp2,Hsph1,Map4k4,Tlr3,Sphk1,Tlr6,Il1b,Mlkl,Zc3h12a |
| 2.258e-09 | -19.91 | regulation of leukocyte mediated cytotoxicity | biological process | GO:0001910 | 108 | 27 | 20694 | 1406 |
Serpinb9,Ripk3,H2-Q7,H2-Q4,Tap2,H2-T22,Stap1,H2-T10,Clec2d,Il12b,Pik3r6,Nectin2,Tap1,Lgals9,Dnase1l3,H2-T24,Stat5a,Cxcl1,Raet1e,Klrk1,Rasgrp1,Il18rap,Pvr,H2-Q6,H60b,H2-M2,Ccl2 |
| 2.277e-09 | -19.90 | GO_TAXIS | MSigDB lists | GO_TAXIS | 419 | 70 | 15632 | 1249 |
Flrt2,Map2k1,Pdgfrb,Ccr1,Pde4b,Ccl5,Vasp,Cxcl2,Nrp2,Ext1,Pdgfb,Scn1b,Cxcl10,Nr4a3,Fpr1,Ptafr,Ptprj,Vegfc,Plaur,Il1b,Pf4,Cxcl1,Vcam1,Cmklr1,Csf3r,Egr2,Ccl3,Il10,Sema3c,S100a8,Ednrb,Ccrl2,Met,Itga9,Lpar1,Sema4a,Pik3cd,Ptk2,Egr3,Sema4c,Kif5c,Trem1,Lhx2,Xcr1,Ccl4,Dock4,Nr4a1,Flt1,Spn,Ezr,Cx3cr1,Syk,Flrt3,Ccl12,Itgav,Sbds,Cxcl14,Edn1,Ccr3,Il6,Ccl2,Fpr2,Ccl22,Cdk5r1,Cx3cl1,Evl,Klf7,Angpt1,Plau,Gpc1 |
| 2.285e-09 | -19.90 | GO_RESPONSE_TO_HORMONE | MSigDB lists | GO_RESPONSE_TO_HORMONE | 857 | 118 | 15632 | 1249 |
Notch1,Daxx,Agtrap,Socs1,Sphk1,Hif1a,Icam1,Egr2,Rhoq,Nr3c1,Casp3,Acvr1,Ccnd1,Mdm2,Dusp1,Src,Rbbp8,Timp1,Thbs1,Il1rn,Gng12,Ldha,Ptger4,Lox,Ptafr,Serpinb9,Ptgs2,Pdgfb,Btg2,Nampt,Junb,Gclc,Pde3b,Gng11,Egr1,Il4ra,Phip,Prkce,Il6,Edn1,Nqo1,Ccl12,Jun,Fos,Hcls1,Socs7,Prkar2b,Igf1r,Socs3,Stat1,Tnfsf4,Adrb2,Acsl1,Sirt1,Ccne1,Ptch1,Il10,Gnb4,Cd38,Fabp3,Tnc,Stat3,Mecp2,Errfi1,Plod3,Stat5a,Tnf,Il1b,Keap1,Gng4,Hmox1,Nr4a3,Trib3,Stxbp3,Rab10,Fzd1,Mmp13,Inhba,Gja1,Ccl5,Pdgfrb,Atp6v1d,Fosb,Asns,Tspo,Me1,Ahr,Fas,Irs2,Nr1h3,Sdc1,Kat2b,Mmp14,Pla2g4a,Ifnb1,Ass1,Nr4a1,Ptpn2,Cited2,Dnaja1,Gfpt1,Jak2,Cdkn1a,Pmepa1,H3f3b,C3,Max,Ptk2,Hmgcs1,Lyn,Med13,Slc9a1,Rnf14,Nfkb1,Casp8,Plod2,Pid1,Cav1 |
| 2.309e-09 | -19.89 | regulation of cellular component biogenesis | biological process | GO:0044087 | 923 | 111 | 20694 | 1406 |
Rhoc,Rac3,Rab3ip,Gda,Ptk2,Mmp14,Phldb1,Fzd5,Myo10,Nupr1,Fas,Tmsb10,Carmil1,Dnajb2,Flrt2,Ntng2,Edn1,Sipa1l1,Stap1,Rhoq,Birc2,Hspa2,Antxr1,Ezr,Cdc42ep4,Evl,Aim2,Eif2ak2,Fchsd2,Hspa1a,Cenpj,Mecp2,Ptger4,Chmp4b,Notch1,Swap70,Mpp7,Tlr2,Rictor,Crbn,Tlr6,Flrt3,Sphk1,Ptprj,Hcls1,Hap1,Bcl2l11,Csf3,Hck,Src,Cdc42ep2,Map4k4,Wdr43,Tmod3,Piezo1,Lpar1,Irgm2,Xaf1,Agrn,Mefv,Fscn1,Pmepa1,Rgcc,Icam1,Kat2b,Wars,Dync1h1,Tmem67,Dr1,Nlgn2,Sdc4,Parp10,Pikfyve,Acvrl1,Kif9,Ikzf1,Met,H3f3b,Nck1,Cx3cl1,Tnf,P2ry12,Fzd1,Stxbp1,Kdr,Syk,Gpsm2,Palld,Trim30a,Ahr,Sdc1,Myadm,Spire1,Prkce,Cav1,Gja1,Lmo4,Asap3,Dbnl,Adgrl2,Sema4a,Whamm,Plek,Hspa1b,Plk2,Rapgef2,Vasp,Syne2,G3bp2,Atm,Cyfip1 |
| 2.321e-09 | -19.88 | positive regulation of secretion | biological process | GO:0051047 | 529 | 74 | 20694 | 1406 |
Serp1,Rasgrp1,Arid5a,Tnfsf4,Sdc4,Glrx,S100a8,Il10,Ezr,Mmp13,Stxbp1,Syk,Vegfc,Ptger4,Aim2,Tnf,P2ry2,Il1a,Adora2a,Ccl3,Cacna1d,Ednrb,Gsdmd,Fzd5,Cd14,Kmo,Tlr1,Edn1,Fgr,Nlgn2,Ifih1,Rgcc,Hcar2,Hk1,Irs2,Nod2,Clec5a,Rab9,Src,Cd38,Gpr68,Casp4,Cd34,Nr3c1,Sec24a,Adora2b,Casp1,Hif1a,Ptafr,Il6,Lif,Ripk2,Tnfsf15,Sirt1,Clec4n,Il1b,Cd274,Nlrp3,Lgals9,Gja1,Htr2b,Jak2,Ifnar1,Sphk1,Ddx58,Sdc1,Clec4e,Clcf1,Frmd4a,Tlr2,Prkce,Tnfrsf14,Il4ra,Osm |
| 2.326e-09 | -19.88 | response to hypoxia | biological process | GO:0001666 | 193 | 38 | 20694 | 1406 |
Kdr,Plekhn1,Flt1,Higd1a,Hif1a,Mecp2,Atm,Ak4,Vegfc,Cited2,Plk3,Nos2,Fam162a,Plau,Cd38,Slc9a1,Adrb2,Pdk3,Bmp2,Ddit4,Casp1,Pml,Edn1,Itpr1,Birc2,Plat,Egr1,Vasn,Prkce,Hmox1,Rgcc,Cav1,Pgk1,Sirt1,Il18,Bnip3,Myc,Notch1 |
| 2.371e-09 | -19.86 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE_BY_P53_CLASS_MEDIATOR | 35 | 16 | 15632 | 1249 |
Ifi207,Cdkn1a,Ifi204,Ifi214,Nupr1,Pml,Dyrk2,Sirt1,Ifi203,Ddit4,Ifi211,Ifi208,Mndal,Ifi209,Ifi205,Ifi213 |
| 2.413e-09 | -19.84 | OISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN | MSigDB lists | OISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN | 248 | 49 | 15632 | 1249 |
Gna15,Gem,Procr,Ksr1,Smpdl3b,Rcn1,Mthfd2,Rbms1,Cd82,Plac8,Cnn2,Syk,Tagln,Cited2,Rhof,Mmp14,Rin2,Palld,Papss2,Arl4a,Cdc42ep2,Ahr,Cdyl,Hopx,Nrp2,Ddit4,Bst1,Vasp,Dgka,Stx11,Hk2,Rnf19b,Traf3ip2,Ptgs2,Il2rg,Acsl5,Vcam1,Inpp1,Vegfc,Igf2bp2,Timp1,Fut8,Ly75,Arhgap26,Irf2,Marcksl1,Myd88,Cd164,Irak3 |
| 2.416e-09 | -19.84 | PID_AP1_PATHWAY | MSigDB lists | PID_AP1_PATHWAY | 76 | 24 | 15632 | 1249 |
Hif1a,Egr1,Atf3,H2-Q7,Plau,Jun,H2-Q6,Timp1,Fos,Ccl12,Bcl2l11,Dusp1,H2-Q4,Ccnd1,Il6,Myc,Nr3c1,Edn1,Mafg,Mmp9,Fosb,Il10,Gja1,Junb |
| 2.425e-09 | -19.84 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_DN | 188 | 41 | 15632 | 1249 |
Rars,Trim13,Tnfrsf8,Cd83,Relb,Ifit1,Plod3,Bcl2a1b,Bcl2l11,Sqstm1,Dusp1,Tnf,Bcl6,Dusp2,Dusp8,Ccng2,Bcl2a1d,Rin2,Pim2,Rac3,Kif5c,Psmb6,Rnf19b,Mtmr14,Cdc42ep4,Plat,Tnfaip2,Hcls1,Cxcl1,Bcl2a1a,Il1b,Trafd1,Gch1,Tnfrsf1b,Slc7a8,Irf7,Zc3h12c,Alas1,St3gal5,Tmem176a,Rnf19a |
| 2.438e-09 | -19.83 | MAHADEVAN_RESPONSE_TO_MP470_DN | MSigDB lists | MAHADEVAN_RESPONSE_TO_MP470_DN | 16 | 11 | 15632 | 1249 |
Dusp5,Atf3,Nfil3,Gem,Ppp1r15a,Gdf15,Sod2,Gadd45b,Dusp1,Maff,Myc |
| 2.438e-09 | -19.83 | XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR | MSigDB lists | XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR | 16 | 11 | 15632 | 1249 |
Ifit1bl2,Ifit1bl1,Isg15,Irf7,Oas3,Plscr1,Thbs1,Slc9a1,Zeb1,Maff,Plaur |
| 2.447e-09 | -19.83 | response to organonitrogen compound | biological process | GO:0010243 | 825 | 102 | 20694 | 1406 |
Icam1,Egr1,Rab10,Nod1,Irs2,Kat2b,Tmem67,Vcam1,Hmgcs1,Stxbp3,Phip,Igf1r,Larp1,Junb,Actb,Ednrb,Pde4b,Tnf,Jun,P2ry12,Egr2,Cacybp,Pde3b,Syk,Sh3bp4,Stat4,Fcgr2b,Myd88,Agtrap,Prkce,Nr4a3,Ahr,Ccnd1,Nfkb1,Sell,Cav1,Casp3,Itpr1,Htr2b,Il1b,Trim13,Trib3,Sirt1,Mmp9,Pdgfc,Mdm2,Jag1,Cyfip1,Ppp2r2a,Prnp,Nmral1,Rapgef2,Cpeb4,Timeless,Nod2,Dnajb2,Homer1,Rhoq,Pde1b,Socs7,Casp7,Zeb1,Ptk2,Ptpn2,Htr2a,Myc,Itga4,Irak3,Adora2a,Socs1,Serpina3g,Stat5a,Atp2b4,Mecp2,Nr4a1,Ezr,Irf1,Nfkbia,Tlr9,Adrb2,Hdac1,Slc9a1,Tlr2,Tnfaip3,Tlr6,Jak2,Stat1,Notch1,Nlrp3,Akt3,Il18,Rnf139,Serpina3f,Sesn3,Ripk2,Ldlr,Stat2,Casp1,Fpr2,Src,Stat3,Casp4 |
| 2.457e-09 | -19.82 | GO_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | MSigDB lists | GO_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | 119 | 31 | 15632 | 1249 |
Clcf1,Il1b,Tnfsf4,C3,Ripk2,Irf1,Il12b,Il12rb1,Sirt1,Fzd5,Samsn1,Il10,Irf7,Il27,Cd80,Ripk3,Tnfaip3,Hlx,H2-Q7,Malt1,Il4ra,Nlrp3,Rsad2,Ifnb1,Spn,H2-Q4,Tnf,Traf2,H2-Q6,Cd40,Bcl6 |
| 2.502e-09 | -19.81 | regulation of interleukin-1 beta secretion | biological process | GO:0050706 | 40 | 16 | 20694 | 1406 |
Arg2,Ifnar1,Ripk2,Tnfaip3,Nod2,Aim2,Tlr2,Ccl3,Hk1,Casp4,Zc3h12a,Gsdmd,Fzd5,Pml,Casp1,Nlrp3 |
| 2.525e-09 | -19.80 | GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_DN | MSigDB lists | GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_DN | 181 | 40 | 15632 | 1249 |
Ddx58,Ifih1,Rtp4,Nxf1,Pde3b,Ifit1,Slfn5,Plac8,Ifit2,Usp53,Bcl2l11,Ets2,Ikzf1,Irgm2,Slfn8,Ppp2r5a,Mmp14,Parp9,Rsad2,Ptgir,Filip1l,Phf6,Gpd2,Nr4a3,Ifit3b,Sema4a,Slfn9,Clic4,Adam19,Cmpk2,Pde4b,4930523C07Rik,Dusp6,Ifit3,Il10,Lmo4,Plekha2,Cnn3,Nrp2,Dgka |
| 2.525e-09 | -19.80 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDC_DN | 181 | 40 | 15632 | 1249 |
Pttg1,Ifih1,Isg15,Psme1,Rars,Mcm10,Rhoc,Olfml3,Slc28a2,Msr1,Arid5a,Fos,Trip10,Il18bp,Cept1,Parp9,Dhx58,Ikzf1,Fut8,Katna1,Aftph,Slc15a3,Mcm6,Pdzd11,Ifi35,Pim2,Mitd1,Rap2c,Kdr,Tor1aip1,Slc31a2,Tor3a,Bst1,Snx2,Met,Uba7,Sap30,Isg20,Ociad1,Nmi |
| 2.525e-09 | -19.80 | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN | 181 | 40 | 15632 | 1249 |
Il1a,Ifih1,Sphk1,Fas,Psme1,Prrg4,Notch1,Tle3,F10,Sla,Gpr18,Tet2,Hspa1a,Agrn,Casp1,Cdyl2,Phlpp1,Nqo1,Cpd,Phgdh,Lrch1,Rab11fip1,Trib3,Cd200,Igf1r,Jak2,Rsbn1,Ralgds,Cd86,Il10,Vps54,Slc13a3,Nfkbid,Egln3,Ppp2r3a,Etv6,Cnn3,Ksr1,Bcl9,Atxn7l1 |
| 2.525e-09 | -19.80 | GSE22432_MULTIPOTENT_PROGENITOR_VS_PDC_UP | MSigDB lists | GSE22432_MULTIPOTENT_PROGENITOR_VS_PDC_UP | 181 | 40 | 15632 | 1249 |
Rtp4,Gbp3,Ifih1,Arl4a,Pttg1,Ccnd2,Stxbp1,Prpf38a,Tap1,Ifit1,Traf2,Cst7,Parp8,Plac8,Stk40,Rsad2,Glipr2,Treml2,Arid5b,Acsl1,Slamf8,Stat1,Hmox1,Endod1,Xkr8,Htr2b,Glrx,Cmpk2,Acp2,Trafd1,Ppp2r2a,Rgs1,Gtpbp2,Golga3,Nos2,Mov10,Asah2,Tor3a,Tdrd7,Rab10 |
| 2.525e-09 | -19.80 | GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_DN | MSigDB lists | GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_DN | 181 | 40 | 15632 | 1249 |
Adar,Hvcn1,Ahr,Icam1,Rtp4,Gbp3,Slc30a1,Ifih1,Nlrp3,Fgl2,Mlkl,Cebpd,Prdx5,Rsad2,Acvrl1,Plac8,Agrn,Msr1,Cited2,Serp1,Cd40,Plcl2,Slfn3,Adam19,Epsti1,Smox,Ifi35,Dyrk2,Tgfbi,Fam111a,Rcsd1,Slpi,Timeless,Tdrd7,Slc31a2,Slc7a8,Lgals9,Hopx,Slfn4,Ogfr |
| 2.525e-09 | -19.80 | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN | MSigDB lists | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN | 181 | 40 | 15632 | 1249 |
Ifi35,Gng4,Rtn1,Irf1,Serpinb9,Idi1,Dio2,Ptges,Wdr43,Trafd1,Psmb8,Nfkb1,Nmi,Zfp36,Rnf19a,Inhba,Kctd12,Psme1,Ier2,Egr1,Mapkapk2,Hif1a,Gbp3,Psmb10,Rgs3,Gbp2,Mdfic,Tle3,Nr4a1,Src,Cnn2,Hsph1,Psmb9,Dnaja1,Dusp2,Egr2,Fgl2,Hdac1,Prdx5,Tapbp |
| 2.531e-09 | -19.79 | lymphocyte activation involved in immune response | biological process | GO:0002285 | 123 | 29 | 20694 | 1406 |
Stx11,Dock10,Sema4a,Stat3,Batf,Icosl,Ifna6,Spn,Ifna4,Ifna5,Ifna2,Il6,Ptger4,Il12b,Cd180,Swap70,Ifna1,Itgal,Irf4,Fgl2,Plcl2,Gadd45g,Clec4e,Icam1,Clec4d,Tnfaip3,Notch2,Relb,Ifnb1 |
| 2.588e-09 | -19.77 | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | 94 | 27 | 15632 | 1249 |
Glrx,Pgk1,Fam162a,Vegfc,Plaur,Lox,Ak4,Egln3,Hk2,Pdgfb,Serpine1,Cav1,P4ha1,Gja1,Eno2,Gys1,Pfkfb3,Gbe1,Egr1,Ccng2,Bnip3,Cited2,Slc2a1,Itpr1,Fos,P4ha2,Plac8 |
| 2.598e-09 | -19.77 | GOLDRATH_ANTIGEN_RESPONSE | MSigDB lists | GOLDRATH_ANTIGEN_RESPONSE | 320 | 58 | 15632 | 1249 |
Mdfic,Mcm10,Prdm1,Itga4,H2-Q7,St3gal6,Cd74,Rhoq,Slc39a4,Carhsp1,Cish,Casp3,Hspa2,Fgl2,Errfi1,N4bp1,Casp1,Dusp1,H2-Q6,Clic4,Glrx,Slc31a1,Ptger4,H2-Ab1,Ttc39b,Serpinb9,Pim1,H2-Aa,Il12rb1,Ccl5,Myadm,Snx10,Txn1,Slc4a7,Hopx,Sgcb,Tpi1,Pgm1,Irf4,H2-Q4,Gadd45b,Cited2,Cyfip1,Ccl4,Nfil3,Ell2,C3,Lyn,Ier3,Mthfd2,Odc1,Plscr1,Trip13,Slpi,Hat1,Il18rap,Gem,Irf8 |
| 2.603e-09 | -19.77 | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_DN | MSigDB lists | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_DN | 174 | 39 | 15632 | 1249 |
Mtmr14,Endod1,Ripk2,Irf1,Rcsd1,Mcm6,Dek,Vcam1,Nfxl1,Rgs1,Gca,Abcc1,Cmpk2,Ccnj,Slc4a7,Nfkb1,Serpine1,Gem,Zc3h7a,Trim21,Csf1,Trip13,Stx6,Cxcl2,Il1a,Socs1,Arrdc4,Sgcb,Apaf1,Enpp4,Dync1h1,Klhl25,Homer1,Arhgef3,Tcf4,Tmem184b,Sat1,Casp3,Nfkbie |
| 2.657e-09 | -19.75 | regulation of chemokine production | biological process | GO:0032642 | 88 | 24 | 20694 | 1406 |
Adora2b,Myd88,Hdac1,Tlr9,Tnf,P2ry2,Eif2ak2,Il1a,Mul1,Ripk2,Arg2,Mcoln2,Il6,Il1b,Mefv,Lgals9,Cd74,Il18,Ccl5,Egr1,Tlr2,Il4ra,Nod2,Tlr3 |
| 2.727e-09 | -19.72 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_UP | 23 | 13 | 15632 | 1249 |
Ifi213,Ifi205,Ifi209,Mndal,Ifi208,Ifi211,Ifi203,Cd200,Tmem176b,Ifi214,Arid5b,Ifi204,Ifi207 |
| 2.758e-09 | -19.71 | negative regulation of nucleobase-containing compound metabolic process | biological process | GO:0045934 | 1395 | 152 | 20694 | 1406 |
Nupr1,Nsd3,Radx,Edn1,Spen,Tent2,Klf2,Kdm5b,Etv6,Zeb1,Tle3,Nr1h3,Ptpn2,Cebpd,Zfp36,Myc,Hopx,Slfn1,Aebp2,Ets2,Hspa1a,Arid4a,Cenpj,Mecp2,Hinfp,Ddit4,Tnfsf4,Dach1,Ezr,Irf1,Hdac1,Dcp2,Prdx5,Bcor,Klf8,Foxp4,Hat1,Cdyl2,Mndal,Notch1,Pid1,Gfi1,Zc3h12a,Ifi211,Gbp4,Ifi208,Parp9,Znfx1,Pdgfb,Hcls1,Nfkbie,Ifi203,Ccne1,Jarid2,Src,Stat3,Nr3c1,Egr1,Notch2,Zhx2,Jdp2,Dnajb4,Dr1,Eno1,Kmt5a,Mtdh,Rbl1,Larp1,Cgas,Txn1,Gclc,Parp3,Ppp1r15a,Ednrb,Junb,Bcl6,Max,Arid5b,Ifi214,Plk3,Tnf,Ifi204,Daxx,Mdfic,Jun,Tcf4,Fzd1,Cited2,Arid5a,Atf3,Phf6,Ifi207,Rbbp8,Pml,Acvrl1,Mafk,Met,Ikzf1,Noct,Myd88,Nck1,Zfp281,Mxd1,Prdm1,Ifi209,Ahr,Ccnd1,Psmd10,Cdk5r1,Nr4a3,Cav1,Klf7,Zmynd15,Nfkb1,Relb,Gja1,Ptch1,Riox2,Ifi205,Sqstm1,Il1b,Hhex,Hmga2,Trib3,Mapkapk2,Irf8,Etv3,Klf3,Ier3,Sirt1,Mdm2,Rfx5,Btg2,Ifi213,Ahrr,Ciita,Sap30,Dusp1,Hif1a,Nfil3,Tent4a,Atm,Kdm4a,Bmp2,Rel,Zbtb5,Nmral1,Cdyl,Dusp5,Timeless,Cd38,Mier3 |
| 2.810e-09 | -19.69 | GROSS_ELK3_TARGETS_DN | MSigDB lists | GROSS_ELK3_TARGETS_DN | 31 | 15 | 15632 | 1249 |
Fam162a,Cxcl1,Gbe1,Ptgs2,Upp1,Csrnp1,Socs3,Maff,Rsad2,Slpi,Il6,Ifi44,Bnip3,Oas3,Plek |
| 2.810e-09 | -19.69 | WANG_METHYLATED_IN_BREAST_CANCER | MSigDB lists | WANG_METHYLATED_IN_BREAST_CANCER | 31 | 15 | 15632 | 1249 |
Dusp1,Klf6,Gdf15,Myo1b,Cav1,Zyx,Slc9a1,Slc7a5,Inhba,Maff,Upp1,Irs2,Sphk1,Thbs1,Etv5 |
| 2.810e-09 | -19.69 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP | 31 | 15 | 15632 | 1249 |
Cdc42ep2,Dusp14,Tfec,Cdkn1a,Atp11b,Etv5,Cd55,Plagl1,Osgin2,Trib3,Prnp,Errfi1,Gch1,Src,Klf2 |
| 2.830e-09 | -19.68 | negative regulation of leukocyte cell-cell adhesion | biological process | GO:1903038 | 131 | 30 | 20694 | 1406 |
Arg2,H2-Aa,Cd80,Socs1,Slfn1,Adora2a,Hlx,Peli1,H2-Ab1,Prnp,Irf1,Spn,Cd86,Sdc4,Tnfsf4,Ass1,Casp3,Tnfrsf14,Il4ra,Tarm1,Ifnb1,Nfkbid,Zc3h12a,Ptpn2,Fgl2,Pde5a,Bcl6,Cd274,Lgals9,Cd74 |
| 2.863e-09 | -19.67 | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP | 189 | 41 | 15632 | 1249 |
Bcl6,Gpsm2,Klf6,Ifit2,Casp1,Insl6,Phlpp1,Dhx58,Rsad2,B3gnt5,Ccng2,Gbp9,Gbp4,Prkce,Calcrl,Kmo,Slco3a1,P2ry14,Rtp4,Agtrap,Sell,Gbp3,Slc30a4,Tmem176b,Mdfic,Rbm43,Casp4,Atp6v1d,Oas1a,Cysltr2,Tifa,Irf1,Ms4a6d,Smox,Oas1g,Traf3ip2,Uchl1,Vegfc,Dio2,Frmd6,Gtpbp2 |
| 2.863e-09 | -19.67 | GSE7852_TREG_VS_TCONV_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_UP | 189 | 41 | 15632 | 1249 |
Cish,Itgb8,Fcgr2b,Cpd,Dusp4,Phlpp1,Ogfrl1,N4bp1,Tank,Swap70,Cd80,Sdc4,Cd83,Mdfic,Plagl2,Relb,Mapkapk2,Arrdc4,Ppm1l,Plagl1,Ubash3b,Prnp,Isg20,Reps1,Trim14,Nfkb1,Tnfrsf1b,Birc3,Vps54,Irf8,Rgs1,Tmem123,Cldnd1,Tnip1,Sh3bgrl2,Abcc1,Pmepa1,Endod1,Ebi3,Arid5b,Map3k8 |
| 2.863e-09 | -19.67 | GSE17721_CTRL_VS_POLYIC_2H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_2H_BMDC_DN | 189 | 41 | 15632 | 1249 |
Ifit1,Cd14,Crlf3,Jmjd6,Icam1,Spata13,Tab2,Nupr1,Marcksl1,Ier2,Prdm1,Nck1,Cpd,Gsr,Rai14,Peli1,Gpr84,Klhl25,Cst7,Crbn,Gramd1a,Cdkn1a,Abcc1,Hcar2,Clcf1,Cflar,Arid5b,Rtn1,Ell2,Egr3,Endod1,Ccrl2,Inhba,Csf1,Zc3h7a,P2ry2,Ppp1r15a,Gch1,Brd2,Jarid2,Junb |
| 2.868e-09 | -19.67 | GO_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS | 257 | 50 | 15632 | 1249 |
Cdkn1a,Ifi204,Irf1,Rcsd1,Map2k4,Nox1,Sirt1,Casp2,Ifi203,Ifi211,Slc9a1,Cav1,Tnfsf14,Casp8,Mndal,Atm,Nfkb1,Ifi207,Tspo,Ifi214,Fas,Egr1,Kcnj2,Bnip3,Myc,Cnn2,Il1b,Ptgs2,Ptafr,Ptger4,Tlr3,Ifi208,Ppp1r15a,Gja1,Hvcn1,Relb,Myd88,Tnfrsf8,Hif1a,Errfi1,Tlk2,Mdm2,Gpr68,Psmb9,Ifi205,Ifi209,Cd40,Ifi213,Casp1,N4bp1 |
| 2.960e-09 | -19.64 | chemokine-mediated signaling pathway | biological process | GO:0070098 | 69 | 21 | 20694 | 1406 |
Ccl4,Cxcl10,Ccrl2,Cxcl9,Ccl7,Ccl3,Ccl5,Cxcl11,Cx3cl1,Cxcl2,Cxcl1,Cxcl3,Ccl2,Gpr35,Ccl22,Pf4,Ccl8,Ccr3,Ccl9,Ccl12,Ccr1 |
| 2.974e-09 | -19.63 | REACTOME_TOLL_RECEPTOR_CASCADES | MSigDB lists | REACTOME_TOLL_RECEPTOR_CASCADES | 107 | 29 | 15632 | 1249 |
Irf7,Map2k1,Dusp6,Ikbkg,Nfkbib,Tlr1,Tlr2,Map2k4,Ripk2,Tlr9,Tlr3,Ikbke,Nfkb2,Irak2,Ppp2r1b,Jun,Fos,Nfkbia,Dusp4,Nod2,Peli1,Cd180,Tab2,Mapkapk2,Tlr6,Irak3,Cd14,Myd88,Nod1 |
| 2.991e-09 | -19.63 | GSE28726_NAIVE_VS_ACTIVATED_NKTCELL_DN | MSigDB lists | GSE28726_NAIVE_VS_ACTIVATED_NKTCELL_DN | 182 | 40 | 15632 | 1249 |
Ccl4,Bcl2a1a,Cflar,Gfi1,Ap3m2,Acp2,Cd200,Dusp5,Ripk2,Egr3,Mthfd2,Ier3,Acsl1,Slc7a5,Bcl9,Il18rap,Eef1e1,Nfkb1,Tnfrsf1b,Eif4g2,Gem,Rrs1,Lcp2,Daam1,Rras2,Plagl2,Ahr,Palld,Atf3,Traf1,Il4ra,Pnp2,Egr2,Cycs,Bcl2a1d,Cox17,Ifrd1,Bcl2l11,Bcl2a1b,Ezr |
| 2.991e-09 | -19.63 | GSE31082_DP_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DP_VS_CD8_SP_THYMOCYTE_DN | 182 | 40 | 15632 | 1249 |
Crim1,Batf,Rbm43,Adar,Traf1,Rars,Cept1,Dock10,Irf4,Dusp2,Ly75,Arhgef3,Eno1,Axl,Rnf114,Agrn,Zhx2,Notch2,Snapc1,Sec24a,Odc1,Nr4a3,Acsl1,Naa25,Herc6,Parp3,Ppa1,Stat4,Hivep3,Wars,Oas2,Tdrd7,Inpp5b,Icosl,Trim14,Flnb,Lad1,Cd86,Plekha2,Atm |
| 2.991e-09 | -19.63 | GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_DN | 182 | 40 | 15632 | 1249 |
Mdm2,Gpr84,Batf2,Klhl25,Acpp,Arhgef3,Ets2,Hsph1,Spryd7,Ddhd1,Cd38,Klf7,Slc25a25,Icam1,Spata13,P2ry14,Marcksl1,Csf3,Rnf19a,Ccrl2,Vasp,Ppp2r3a,Btg2,Procr,Srxn1,Ampd3,Trip13,Marco,Casp4,Nampt,Tnfrsf1b,Csrp1,Rcl1,Clcf1,Rnf145,Fpr1,Tlr2,Ptk2,Socs3,Itga5 |
| 2.991e-09 | -19.63 | GSE9037_WT_VS_IRAK4_KO_LPS_1H_STIM_BMDM_UP | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_LPS_1H_STIM_BMDM_UP | 182 | 40 | 15632 | 1249 |
Cd40,Jun,Mtus1,Syk,Gypc,Plac8,Tnf,Fam43a,Dusp4,Mdm2,Taf4b,Lztfl1,Myc,Il6,Gclm,1110038F14Rik,Pla2g4a,Trim13,Zfp513,Egr1,Csrnp1,Tmem176b,Slc48a1,Pim3,Sdc4,Pfkfb3,Cenpj,Gem,Ptch1,Tshz1,Stx6,Slpi,Rab20,Tgfbi,Slc31a1,Rnf19b,Kdm6b,Dio2,Slc29a3,Clcn7 |
| 3.031e-09 | -19.61 | Jak-STAT signaling pathway | KEGG pathways | mmu04630 | 158 | 39 | 7931 | 713 |
Ifna2,Tyk2,Ccnd2,Stat1,Il13ra1,Ifna1,Akt3,Il10,Socs7,Pik3cd,Il15ra,Il12rb1,Ifnar1,Il2rg,Stat3,Ifna5,Pim1,Cish,Socs1,Ifnb1,Csf3,Ptpn2,Csf3r,Stat5a,Lif,Socs3,Myc,Stat4,Cdkn1a,Ifna6,Osm,Il12b,Il15,Jak2,Ifna4,Il4ra,Il6,Ccnd1,Stat2 |
| 3.031e-09 | -19.61 | Jak-STAT signaling pathway | KEGG pathways | ko04630 | 158 | 39 | 7931 | 713 |
Pim1,Cish,Ifnb1,Socs1,Csf3r,Lif,Stat5a,Csf3,Ptpn2,Cdkn1a,Stat4,Ifna6,Socs3,Myc,Il4ra,Ifna4,Jak2,Ccnd1,Stat2,Il6,Il12b,Osm,Il15,Stat1,Il13ra1,Ccnd2,Ifna2,Tyk2,Ifna1,Akt3,Il12rb1,Il10,Il15ra,Pik3cd,Socs7,Stat3,Ifna5,Il2rg,Ifnar1 |
| 3.063e-09 | -19.60 | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN | MSigDB lists | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN | 120 | 31 | 15632 | 1249 |
Tiparp,Jun,Klf6,Gadd45b,Dusp4,Ifrd1,Peli1,Dusp2,Irs2,Slc30a1,Prnp,Rnf139,Csrnp1,Mxd1,Tnfaip3,Fosb,Sik3,Ppp1r15a,Rel,Ppp1r15b,Nampt,Cd69,G3bp2,Zfp36,Map3k8,Nr4a3,Etnk1,Kdm6b,Ptger4,H3f3b,Rgs1 |
| 3.193e-09 | -19.56 | GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_UP | MSigDB lists | GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_UP | 197 | 42 | 15632 | 1249 |
Bcl2a1a,Inpp1,Rcan1,Tmem229b,Lyn,Nr4a3,Dnaja2,Snx2,Kctd12,H2-Aa,Zc3h12c,Casp4,Tor3a,Birc3,Slc4a7,Eif4g2,Ppp1r15b,Cd38,Mdfic,Hck,Ciita,Crlf3,Cd83,Fcgr1,Upp1,Cd74,Icam1,Sell,Bcl2a1d,Ctsc,Fcgr2b,Nat2,Rhoq,Slc44a1,Il4i1,Cyfip1,Bcl6,Tcf4,Mgat1,Cd40,Bcl2a1b,Syk |
| 3.274e-09 | -19.54 | MODULE_3 | MSigDB lists | MODULE_3 | 380 | 65 | 15632 | 1249 |
Pdlim7,Slc7a5,Ifi208,Maff,Dusp6,Gja1,Gdf15,Map4k4,Serpine1,Plk2,Thbs1,Gng12,Plaur,Cd55,Mcm6,Lox,Pnp2,Ccnd1,Apobec3,Slc16a3,Ifi213,Ifi205,Birc2,Ifi209,Swap70,Mtus1,Myo10,Crim1,Stau1,Plk3,Calcrl,Trip13,Ifi211,Procr,Cnn3,Ifi203,Eef1e1,Ltbp2,Plod2,Mndal,Casp4,Cav1,Ldlr,Cdkn1a,Rac3,Itga5,Ier3,Rcn1,Ifi204,Ctsc,Nqo1,Ccl12,Cited2,Zyx,Tspan3,Cyfip1,Gng11,Rnd3,Extl2,Dusp14,Ifi207,Gbe1,Tpx2,Ifi214,Pttg1 |
| 3.284e-09 | -19.53 | GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 501 | 79 | 15632 | 1249 |
Sirt1,Rabgef1,Ppp1r15b,Ednrb,Cav1,Pid1,Tnip1,Igf1r,Dusp16,Prkar2b,Pmepa1,Cdkn1a,Socs7,Socs3,Aida,Lpar1,Trib1,Lyn,Edn1,Spry2,Ppp2r5a,Il6,Myc,Stap1,Dusp2,Dusp4,Ezr,Gadd45b,Flrt3,Psmd10,Dnaja1,Ptpn2,Jun,Adar,Tspo,Spred1,Angpt1,Dusp14,Nck1,Atf3,Cdkn2d,Ubash3b,Kat2b,Prnp,Irs2,Ddit4,Pdgfb,Inhba,Plek,Dusp6,Myadm,Ppp1r15a,Samsn1,Flrt2,Il1b,Ptprj,Uchl1,Zc3h12a,Dusp5,Trib3,Casp3,Stat3,Cish,Dusp8,Errfi1,Tnf,Hsph1,Dusp1,Rgs14,Swap70,P2ry13,Rgs3,Irak3,Mvp,Tnfaip3,Hhex,Lif,Rhoh,Socs1 |
| 3.288e-09 | -19.53 | KEGG_MAPK_SIGNALING_PATHWAY | MSigDB lists | KEGG_MAPK_SIGNALING_PATHWAY | 258 | 50 | 15632 | 1249 |
Hspa2,Casp3,Dusp8,Traf2,Hspa1a,Dusp1,Tnf,Daxx,Relb,Cd14,Il1a,Tab2,Rapgef2,Pdgfb,Pdgfrb,Map2k1,Dusp6,Map4k4,Gng12,Il1b,Prkx,Nfkb2,Map3k8,Crkl,Dusp5,Dusp4,Gadd45g,Pla2g4a,Dusp2,Myc,Fos,Jun,Nr4a1,Gadd45b,Map3k6,Dusp14,Rras2,Fas,Mapkapk2,Rasgrp1,Akt3,Flnb,Nfkb1,Ikbkg,Dusp16,Cacna1d,Cacnb3,Map2k4,Max,Rac3 |
| 3.302e-09 | -19.53 | negative regulation of macromolecule biosynthetic process | biological process | GO:0010558 | 1434 | 155 | 20694 | 1406 |
Hmga2,Hhex,Il1b,Irf8,Trib3,Sirt1,Klf3,Etv3,Btg2,Rfx5,Mdm2,Nr4a3,Psmd10,Cdk5r1,Ccnd1,Ifi209,Ahr,Relb,Nfkb1,Zmynd15,Klf7,Cav1,Riox2,Ptch1,Gja1,Itgav,Ifi205,Sqstm1,Bmp2,Zbtb5,Rel,Dusp5,Cdyl,Nmral1,Mier3,Cd38,Timeless,Cpeb4,Ifi213,Ahrr,Sap30,Ciita,Hif1a,Dusp1,Kdm4a,Il6,Nfil3,Gclc,Txn1,Parp3,Junb,Ednrb,Ppp1r15a,Arid5b,Ifi214,Max,Bcl6,Egr1,Jdp2,Notch2,Zhx2,Eno1,Dr1,Dnajb4,Larp1,Rbl1,Mtdh,Kmt5a,Ago3,Arid5a,Pml,Rbbp8,Ifi207,Atf3,Phf6,Ikzf1,Met,Acvrl1,Mafk,Prdm1,Mxd1,Zfp281,Nck1,Mdfic,Ifi204,Daxx,Tnf,Plk3,Fzd1,Jun,Tcf4,Gfpt1,Cited2,Notch1,Mndal,Gfi1,Rnf139,Zc3h12a,Ifi211,Foxp4,Errfi1,Klf8,Bcor,Prdx5,Cdyl2,Hat1,Nfkbie,Hcls1,Nmi,Jarid2,Ccne1,Ifi203,Stat3,Src,Nr3c1,Gbp4,Znfx1,Parp9,Ifi208,Pdgfb,Nr1h3,Tle3,Kdm5b,Etv6,Zeb1,Zfp36,Cebpd,Ptpn2,Myc,Nsd3,Xrn1,Edn1,Klf2,Spen,Tnfsf4,Hinfp,Il10,Ezr,Dach1,Irf1,Dcp2,Pf4,Hdac1,Eif2ak2,Slfn1,Hopx,Aebp2,Arid4a,Cenpj,Hspa1a,Plekhn1,Ets2,Mov10,Ptger4,Mecp2 |
| 3.375e-09 | -19.51 | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 190 | 41 | 15632 | 1249 |
Hk3,Apaf1,Klf7,Pfkfb3,Clec4e,Cdc42ep2,Icam1,Ifih1,Slco3a1,Irf2,H2-Q7,Cdkn2d,Fgl2,Triobp,Micall2,Slc15a3,Ppp2r5a,H2-Q6,Zyx,Bcl6,Rhbdf2,Ifit1bl1,Klf6,H2-Q4,Cflar,Zcchc2,Tnfaip2,Mppe1,Mafg,Map2k4,Rnf19b,Xkr8,Mmp9,Rapgef2,Pstpip2,Slpi,Nmi,Lcn2,Sipa1l1,Ifit1bl2,Psd4 |
| 3.401e-09 | -19.50 | WIERENGA_STAT5A_TARGETS_GROUP2 | MSigDB lists | WIERENGA_STAT5A_TARGETS_GROUP2 | 50 | 19 | 15632 | 1249 |
Olr1,Nfil3,Rgs1,Cd83,Plau,Traf1,Cxcl10,Arid5b,Mob3b,Ccl22,Stap1,Btg2,Klf2,Ccl12,Ccl5,Sqstm1,Gadd45b,Klf6,Psat1 |
| 3.401e-09 | -19.50 | PRAMOONJAGO_SOX4_TARGETS_UP | MSigDB lists | PRAMOONJAGO_SOX4_TARGETS_UP | 50 | 19 | 15632 | 1249 |
Bnip3,Ampd3,Phlda1,Maff,Ccng2,Dusp4,Sod2,Gdf15,Serpine1,Jun,Tiparp,Myd88,Rnd3,Nfil3,Il1b,Tnfaip3,Ak4,Trib3,Ier3 |
| 3.420e-09 | -19.49 | transmembrane receptor protein tyrosine kinase signaling pathway | biological process | GO:0007169 | 347 | 55 | 20694 | 1406 |
Hap1,Ptprj,Nrp2,Rapgef2,Hck,Stat3,Src,Mvp,Lox,Pdgfb,Flt1,Rgs14,Axl,Mapkapk2,Tiparp,Arf4,Pdgfc,Lyn,Nr4a3,Cdk5r1,Plat,Crkl,Jak2,Casp3,Lcp2,Flrt3,Adgre4,Ddit4,Caml,Nck1,Angpt1,Ccl2,Col4a2,Met,Stat5a,Syk,Ubash3b,Vegfc,Kdr,Ptk2,Arid5b,Gdf15,Pdgfrb,Ptpn2,Irs2,Flrt2,Csf1,Fgr,Socs7,Igf1r,Phip,Sipa1l1,Stap1,Csrnp1,Rhoq |
| 3.539e-09 | -19.46 | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDC_UP | 183 | 40 | 15632 | 1249 |
Vcan,Sele,Ccng2,Ifnb1,Tnc,Dusp2,Tnfsf8,Dusp8,Ccl2,Il6,Egr2,Timp1,Cited2,Jun,Gadd45b,Nr4a1,Tnf,Cd83,Pbx1,Gpc1,Rtp4,Irs2,Tmem176b,Atf3,Nfkbiz,Ier2,Sirt1,Stat4,Inhba,Csf1,Phlda1,Slfn4,Lad1,Slc12a9,Jarid2,Cxcl1,Slfn3,Serpinb2,Arid5b,Ebi3 |
| 3.539e-09 | -19.46 | GSE2585_CTEC_VS_THYMIC_MACROPHAGE_UP | MSigDB lists | GSE2585_CTEC_VS_THYMIC_MACROPHAGE_UP | 183 | 40 | 15632 | 1249 |
Bst1,Egln3,Xaf1,Hk2,Slpi,Ppp1r15a,Tnfsf14,Heatr6,Sesn3,Cflar,Plat,Gcnt2,Xkr8,Smox,St3gal1,Mtdh,C3,Dtx2,Stat1,Cpd,Scarf1,Fcgr2b,Slc39a4,Gbp9,Slc15a3,Rhoq,Gbp4,Psmd10,Ptpn2,Eno1,Zmynd15,Rnf114,Cst7,Ccdc88b,Lpcat2,Ccnd2,Agtrap,Irs2,Isg15,Il4ra |
| 3.539e-09 | -19.46 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN | 183 | 40 | 15632 | 1249 |
Myadm,Ahrr,Gem,Lgals9,Vasp,Ell2,Ptprj,Endod1,Ttc39b,Lyn,Rab20,Chd9,Tnfsf10,Rgs1,Pmepa1,Spsb1,Rhof,Dock4,Cd40,Tcf4,Fchsd2,Slc44a1,Dusp2,Irf4,Stat3,Cpd,Fgl2,Vcan,Treml2,Rhoh,Mxd1,Ppm1l,Arrdc4,Spata13,1600014C10Rik,Ube2f,Tle3,Ahr,Rab3ip,Cd38 |
| 3.539e-09 | -19.46 | GSE17721_POLYIC_VS_CPG_4H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_4H_BMDC_DN | 183 | 40 | 15632 | 1249 |
Aoah,Trmt1l,D16Ertd472e,Hspa1a,Gpr84,Rffl,Ly75,Il4i1,Mdm2,Vcan,P2ry14,Nlrp3,Slc25a25,Sdc4,Hinfp,Pilra,Sla,Clcn5,Tnfaip3,Hck,Lcp2,Lcn2,Heatr6,Rab10,Akt3,Csf1,Car13,Ube2e2,Eef1e1,Cpeb4,Dnaja2,Cd200,Rnf145,Trib1,Sema4a,Fscn1,Acsl5,Fam20c,Pkp4,Ptges |
| 3.578e-09 | -19.45 | T cell activation involved in immune response | biological process | GO:0002286 | 76 | 22 | 20694 | 1406 |
Ifna4,Il6,Ptger4,Ifna5,Ifna2,Sema4a,Stx11,Ifna6,Spn,Stat3,Batf,Relb,Ifnb1,Clec4e,Icam1,Clec4d,Il12b,Gadd45g,Ifna1,Itgal,Irf4,Fgl2 |
| 3.677e-09 | -19.42 | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | 176 | 39 | 15632 | 1249 |
Egln3,Ppp2r3a,Etv6,Ddit4,Cnn3,Dmwd,Il10,Zc3h12c,Gch1,Hk1,Snx10,Eno2,Nfil3,Pfkl,Prkx,Cflar,Mthfd2,Ier3,Trib3,Uaca,Ptgir,Smox,Acvrl1,Ly75,Pdpn,Irf4,D1Ertd622e,Slc2a1,Hspa1a,Eno1,P4ha2,Gys1,Slamf7,Nek6,Tpi1,Marcksl1,Atf3,Prdm1,Hlx |
| 3.709e-09 | -19.41 | regulation of type 2 immune response | biological process | GO:0002828 | 31 | 14 | 20694 | 1406 |
Cd74,Tnfsf4,Nlrp3,Bcl6,Il18,Irf1,Hlx,Nod2,Il4ra,Ifnb1,Rsad2,Clcf1,Il6,Arg2 |
| 3.732e-09 | -19.41 | GO_REGULATION_OF_T_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_T_CELL_PROLIFERATION | 141 | 34 | 15632 | 1249 |
Il12rb1,Icosl,Cd86,Cd274,Il10,Ccl5,H2-Eb1,Il1b,Vcam1,Il18,Il12b,Irf1,Ripk2,Ebi3,Cd55,Tnfsf4,Pde5a,Il6,Peli1,Pnp2,Casp3,H2-Q6,Syk,H2-Q4,Spn,Ripk3,Tnfrsf14,Cd80,Ccdc88b,Il15,Il27,Prnp,Nck1,H2-Q7 |
| 3.836e-09 | -19.38 | response to drug | biological process | GO:0042493 | 821 | 101 | 20694 | 1406 |
Timeless,Thbs1,Cd38,Prnp,Ppp2r2a,Tent4a,Il6,Fos,Cflar,Jag1,Slc7a2,Mmp9,Sirt1,Hp,Axl,Il1b,Gja1,Htr2b,Acod1,Itgav,Casp3,Sell,Cav1,Slc7a11,Nfkb1,Ahr,Nr4a3,Prkce,Cdk5r1,Slc13a3,Stra6l,Casp8,Abcc1,Ccl4,Kdr,P2ry12,Jun,Sod2,Fzd1,Tnf,Daxx,Pde4b,Bnip3,Slc25a12,Nqo1,Actb,Junb,Kdm6b,Igf1r,Larp1,Ifnb1,Nod1,Egr1,Nr3c1,Cd69,Src,Lcn2,Casp1,Nfkbie,Slc25a25,Pdgfb,Traf2,Ripk2,Nos2,Abcc4,Zc3h12a,Notch1,Slc31a1,Sphk1,Crkl,Stat1,Jak2,Inhba,Tnfaip3,Ripk3,Hmox1,Hdac1,Slamf8,Tlr9,Nfkbia,Gk,Ddit4,Ppp1r15b,Mecp2,Abcb1a,Atp2b4,Aim2,Pdpn,Ccl7,Adora2a,Myc,Gclm,Htr2a,Pdgfrb,Slc25a22,Nr1h3,Pde1b,Edn1,Homer1,Serpine1,Nod2 |
| 3.839e-09 | -19.38 | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP | MSigDB lists | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP | 267 | 51 | 15632 | 1249 |
Dcbld2,Plaur,Fmnl2,Thbs1,Plcl2,Cxcl1,Mcm6,Oas1g,Tlr3,Pde7b,Hk2,Fubp1,Dusp6,Slc4a7,Tnfaip3,Cd38,Ripk3,St3gal6,Sphk1,Upp1,Usp18,Mlkl,Cp,Ifi44,Egr2,Timp1,Parp8,Klf6,Dusp16,Idi1,Socs3,Egln3,Oas1a,Smpdl3b,Tifa,Plscr1,Pstpip2,Lcn2,Mfap3l,Tspo,Rtp4,Arl4a,Ddx60,Cpd,Mid1,Dusp4,Edn1,Irgm2,Ikzf1,Ccl12,Rab32 |
| 3.869e-09 | -19.37 | organonitrogen compound metabolic process | biological process | GO:1901564 | 4394 | 387 | 20694 | 1406 |
Mlkl,St3gal5,Btg2,Il1b,Acp2,Isg15,Sla,Pim3,Trib3,Tet2,Ifnar1,Plat,Tlr3,Cdk5r1,Prkce,Keap1,Ppp2r5a,Ppm1l,Dck,Cpeb4,Ube2l6,Bmp2,Casp2,Dusp1,Pgap2,Acvr1b,Saa3,Lox,Phgdh,Otud1,Psmb10,Tha1,Bnip3,Tmem67,Srgn,Acvrl1,Nck1,Mthfd2,Rnf19a,Uba7,Eno2,Nampt,Casp8,Denr,Trim56,Dusp6,Sik3,Rffl,Spsb1,Rnf139,Akt3,Jak2,Sphk1,Tyk2,Irf7,Tnfaip3,Pgk1,Inhba,Ptges,Rictor,Peli1,Phlda1,Pdk3,Trim12c,Eif4g2,Map2k1,Odc1,Usp12,Flt1,Oas1a,Arg2,Lif,Gpc1,Dpy19l1,Psma6,Ube2e1,Tnfsf15,Ptpn2,Pdgfrb,Kdm5b,Prkx,Prag1,Gda,Ptk2,Rhoq,Dusp14,Nupr1,Il15,Gsr,Ccng2,Dnajb2,Cept1,Med21,Psmb9,Gtpbp2,Arrdc4,Birc3,Psmb8,Rnf34,Apobec3,Arid4a,Eef1e1,Herc6,Eif2ak2,Map3k8,Ppm1k,Stat5a,Mmp9,Sirt1,Arel1,Adhfe1,Trim30a,Osm,St3gal3,Plscr1,Sde2,Dusp5,Mrpl52,Ppp2r2a,Tpi1,F10,Mgat1,Mmd,Ksr1,Oasl2,P4ha1,Lpcat2,Nt5c3,Adgb,Gclc,Parp3,Dr1,Nlgn2,Pfkl,Hk1,Uchl1,Kat2b,Jmjd6,Angpt1,Dse,Ccl12,Cpd,Parp10,Asah2,Armc8,Acpp,St3gal6,Rnf135,Plk3,Tnf,Mapkbp1,Lap3,Pcgf5,Zc3h12a,Fgl2,Il18,Chmp4b,Mocs1,Crbn,Usp53,Casp4,B3gnt5,Ldlr,Ccne1,Jarid2,Casp1,Traf2,Mthfr,Usp25,Nek6,Rnf14,Mvp,Ripk2,Mul1,Stk40,Ep400,Irf4,Lnpep,Dtx3l,Gclm,Svbp,Ccr3,Casp7,Cers6,C1ra,Mtmr14,Mmp14,Sgk3,Socs7,Nsd3,Ube2f,Papss2,Klhl25,Pigv,Phlpp1,Rars,Ppp1r15b,Map2k4,Usp42,Naa25,Mdm2,Extl2,Dtx2,Tmtc2,Ppp2r3a,Mapkapk2,Mppe1,Casp3,Cemip2,Itgav,Alas1,Il4i1,Hk2,Ccnd1,Prnp,Fbxo4,Trem1,Plk2,Thbs1,Prdm9,Grk3,Ctsc,Samhd1,Ubr4,Ccnd2,Hif1a,Kdm4a,Dusp8,Sap30,Cflar,Ppp1r15a,Plod3,Mmp25,Dusp4,Kdm6b,Cnot4,Mark2,Plod2,Ext1,Vcam1,Hmgcs1,Kmt5a,Ube2e2,Fut8,Met,Serp1,Myd88,Psat1,Gch1,Setdb2,Kdr,Egr2,Plaat3,Phlpp2,Gfpt1,Ubash3b,Mdfic,Mthfd1l,Hk3,Ranbp2,Bcor,Usp35,Hat1,Ripk3,Trib1,Il12rb1,Src,Hck,Parp12,Smpdl3b,Tapbp,Ampd3,Tpst1,Ero1l,P4ha2,Pdgfb,Ak4,Ikbke,Pde5a,Myc,Kmo,Ppp4r2,Rnf19b,Birc2,Dusp16,Pde1b,Ifih1,Parp8,Tlr9,St3gal1,Scyl2,Dio2,Parp14,Znrf3,Usp31,Mecp2,Dcun1d3,Hopx,Trim12a,Fam20c,Arf4,Trim13,Txnrd1,Axl,Acsl5,Htr2b,Ptch1,Usp18,C1rl,Parp11,Lyn,Chst11,Tnip1,Slc7a11,Cdyl,Sat1,Degs2,Dusp2,Acsl1,Upp1,Atm,Ankib1,Olr1,Malt1,Rnf31,Psmb6,Dusp28,Wars,Map3k6,Fgr,Vrk2,Larp1,Igf1r,Ccl5,Srm,Nod1,Bfar,Ccnj,Eya4,Pim2,Pml,Smox,Stat4,Syk,Trim36,Sod2,Irak2,Tiparp,Gsta3,Znrf1,Vcpip1,Pim1,Tlr2,Hmox1,Plpp1,Asns,Dyrk2,Gcnt2,Map4k4,Tlk2,Ptprj,Ass1,Cmpk2,Htra1,Nos2,Parp9,Irgm2,Zfp36,Irak3,Gadd45g,Itgb8,Enpp4,Morc3,Cop1,Trim21,Sgms2,Carmil1,Pla2g7,Adam19,Plau,Hdac1,Acvr1,S100a8,Mmp13,Hdc,Ptger4,Egln3 |
| 3.952e-09 | -19.35 | REACTOME_IL1_SIGNALING | MSigDB lists | REACTOME_IL1_SIGNALING | 36 | 16 | 15632 | 1249 |
Sqstm1,Ikbkg,Map2k1,Peli1,Nod2,Ripk2,Map3k8,Map2k4,Il1a,Tab2,Irak2,Myd88,Nod1,Il1rn,Il1b,Irak3 |
| 3.959e-09 | -19.35 | regulation of alpha-beta T cell differentiation | biological process | GO:0046637 | 70 | 21 | 20694 | 1406 |
Prdm1,Il27,Bcl6,Ikzf1,Irf1,Il18,Malt1,Zc3h12a,Nlrp3,Cd83,Tnfsf4,Nfkbiz,Syk,Il6,Nfkbid,Il4ra,Il2rg,Hlx,Ripk2,Ap3b1,Socs1 |
| 4.063e-09 | -19.32 | GO_RESPONSE_TO_INTERLEUKIN_1 | MSigDB lists | GO_RESPONSE_TO_INTERLEUKIN_1 | 102 | 28 | 15632 | 1249 |
Ccl4,Irak2,Ptger4,Zc3h12a,Ripk2,Nfkb1,Ccl5,Klf2,P2ry2,Myd88,Cd38,Ccl3,Irak3,Fas,Mthfr,Egr1,Icam1,Ccl22,Hif1a,Sphk1,Cx3cl1,Edn1,Ccl2,Il6,Sele,Src,Ccl12,Psmb9 |
| 4.063e-09 | -19.32 | GROSS_HYPOXIA_VIA_HIF1A_DN | MSigDB lists | GROSS_HYPOXIA_VIA_HIF1A_DN | 102 | 28 | 15632 | 1249 |
Dusp14,Gys1,Pim3,Pfkfb3,Gbe1,Csrnp1,Atf3,Gadd45g,Prdx5,Cpd,Errfi1,Bnip3,Edn1,Spry2,Eno1,Slc2a1,Fos,Nfkbia,Il18,Traf3ip2,Sh3bp4,Zfp36,Sik3,Higd1a,Cav1,Samsn1,Lnpep,Eno2 |
| 4.067e-09 | -19.32 | WANG_CISPLATIN_RESPONSE_AND_XPC_DN | MSigDB lists | WANG_CISPLATIN_RESPONSE_AND_XPC_DN | 221 | 45 | 15632 | 1249 |
Ifi209,Bcl6,Ifi205,Tank,Phf11b,Ifi213,Txnrd1,Acvr1,Glipr2,Ccng2,Casp3,Pnp2,Hif1a,Hlx,Myo1b,Slc31a2,Stoml1,Ifi208,Dnaja2,Vegfc,Acp2,Trip10,Jun,Dusp2,Ifi214,Ifi207,Phf11c,Herc3,Gpc1,Phf11a,Cdc42ep2,Mndal,Casp4,Stx6,Ifi203,Slc9a1,Ifi211,Csf1,Med13,Phf11d,Ifi204,Egr3,Stat1,Filip1l,Cdkn1a |
| 4.180e-09 | -19.29 | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | 184 | 40 | 15632 | 1249 |
Gna15,Cd86,Sh3bp4,Fzd1,Kctd12,Pstpip2,Rcan1,Tgfbi,Il18,Sema4a,Ldha,Il13ra1,Rtn1,Actb,Il1rn,Tnfaip2,Cyfip1,Timp1,P2ry13,Eno1,Cd302,Ets2,Tiparp,Aoah,Rab32,Casp1,Cst7,Ogfrl1,Cebpd,Igsf6,Icam1,St3gal6,Slc30a1,Atf3,Tpi1,Apaf1,Samhd1,Ahr,Rhoc,Myd88 |
| 4.180e-09 | -19.29 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_UP | 184 | 40 | 15632 | 1249 |
Uchl1,Pcgf5,Pdzd11,Ifit3b,Irf1,Cacnb3,Rcan1,Ldlr,Plat,Asf1a,Cxcl1,Trafd1,Plaur,Il15ra,Tor3a,Psmb8,Lap3,Irf7,Hdc,Cav1,Klf2,Ifit3,Stxbp1,Evl,Isg15,Cyth3,Icam1,Adar,Prdx1,Olr1,Tap1,Ifit1,Daxx,Spsb1,Hspa1a,Ppp2r5a,D1Ertd622e,Abcb1a,Rsad2,C1ra |
| 4.180e-09 | -19.29 | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP | MSigDB lists | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP | 184 | 40 | 15632 | 1249 |
Mxd1,Mthfr,Usp25,Ddx58,Cd74,Papss2,Dtx3l,Zbp1,Plagl2,Ifit2,Nr4a1,Dse,Birc2,Rab21,Slfn8,Parp14,Irgm2,Gbp9,Rnf24,Gbp4,Il18bp,Hdac1,Tapbp,Tlr3,Rtn1,Stat1,Rcn1,Grina,Parp11,Ms4a6d,Sema4a,Gfpt1,Ust,Slfn9,Ppp2r1b,Tagap,Birc3,Tuba4a,Vps54,Gbp7 |
| 4.200e-09 | -19.29 | response to dsRNA | biological process | GO:0043331 | 64 | 20 | 20694 | 1406 |
Peli1,Ifna1,Irak3,Ifna6,Nfkbia,Cgas,Zc3hav1,Stat1,Ifna5,Ifna2,Ifih1,Tlr3,Ddx58,Ripk2,Mul1,Cav1,Ifnb1,Ifna4,Nfkb1,Nod2 |
| 4.360e-09 | -19.25 | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_DN | MSigDB lists | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_DN | 177 | 39 | 15632 | 1249 |
Usp18,Cd74,P2ry14,Hhex,Mapkapk2,Dnase1l3,Gclc,Cd302,Tcf4,Tmem184b,Plac8,Ctsc,Fchsd2,Stap1,Ms4a6d,Tgfbi,Lyn,Cd55,Fndc3a,Scyl2,Traf3ip2,Igf1r,Tfec,Jak2,Ppp1r15a,Irf8,Fosb,Casp4,Irf7,Cdyl,Nampt,Sh3bp4,Ccdc25,Stat4,Hk2,Rap1gap2,Kctd12,Tlr1,Slc7a5 |
| 4.429e-09 | -19.24 | FERRARI_RESPONSE_TO_FENRETINIDE_UP | MSigDB lists | FERRARI_RESPONSE_TO_FENRETINIDE_UP | 20 | 12 | 15632 | 1249 |
Ptgs2,Irf1,Sema3c,St3gal1,Atf3,Cxcl2,Sele,Klf7,Bmp2,Slc7a5,Cxcl1,Ddit4 |
| 4.445e-09 | -19.23 | JIANG_HYPOXIA_NORMAL | MSigDB lists | JIANG_HYPOXIA_NORMAL | 284 | 53 | 15632 | 1249 |
Ap3m2,Fam162a,H3f3b,Ell2,Pim2,Rab20,Zfp36,P4ha1,Eno2,Plod2,Cav1,Adar,Sdc4,Nek6,Slc30a1,Ccnd2,Bnip3,Cpd,Kremen1,Sod2,Rnf114,Gadd45b,Nfkbia,Rhof,Cited2,Jun,Ralgds,Gtpbp2,Igf2bp2,Hmox1,Lox,Ak4,G3bp2,Snx10,Serpine1,Ppp1r15a,Tsku,Plagl2,Pdgfc,Cd164,Stau1,Nupr1,Ube2e1,Dtx3l,Psmb10,Upp1,Hif1a,Sat1,Klf6,Dusp1,Ankrd17,Slc2a1,Timp1 |
| 4.448e-09 | -19.23 | GO_NEGATIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 90 | 26 | 15632 | 1249 |
Birc3,Tnfsf14,Mndal,Casp8,Ifi211,Ifi208,Ifi203,Mmp9,Ifi204,Serpinb9,Thbs1,Plaur,Src,Ifi213,Nlrc4,Ifi209,Birc2,Ifi205,Il6,Rffl,Mdm2,Prdx5,Cdkn2d,Ifi214,Rnf34,Ifi207 |
| 4.451e-09 | -19.23 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | MSigDB lists | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | 366 | 63 | 15632 | 1249 |
Hspa2,Dhx58,Tnf,Gypc,Tpst1,Tsku,Pml,Cd180,Icam1,Upp1,Cd74,F11r,Ifih1,Oas2,Dusp6,Ccl5,Gdf15,Asns,Tap2,Irf7,Serpine1,Plat,Nfkb2,Plaur,Il1b,Trafd1,Zhx2,Cd55,Dusp5,Uchl1,Oas1g,Kcnj2,Bnip3,Peli1,Trim36,Slc7a11,Sod2,Ciita,Herc3,Trp53i11,Ahr,Ccl22,Cx3cl1,Ksr1,Csf1,Procr,Cnn3,Isg20,Oas1a,Tmem176a,Psmb8,Birc3,Psat1,Hdc,Fscn1,Ccl4,Agpat4,Lhx2,Cdkn1a,C3,Cd200,Ptgir,Ier3 |
| 4.491e-09 | -19.22 | protein phosphorylation | biological process | GO:0006468 | 769 | 96 | 20694 | 1406 |
Ccng2,Il15,Irak3,Myc,Zfp36,Pdgfrb,Sgk3,Ptk2,Morc3,Ccr3,Prag1,Prkx,Ptger4,Stat5a,Map3k8,Eif2ak2,Tlr9,Map2k4,Scyl2,St3gal1,Acvr1,Jak2,Il12rb1,Rictor,Trib1,Ripk3,Tlr2,Pim1,Tyk2,Irak2,Il18,Akt3,Lif,Nek6,Pdgfb,Flt1,Stk40,Mul1,Ripk2,Ikbke,Map4k4,Hck,Src,Dyrk2,Ccne1,Map2k1,Pdk3,Tlk2,Igf1r,Vrk2,Fgr,Map3k6,Hk1,Ccl5,Mark2,Syk,Stat4,Sik3,Kdr,Mdfic,Tnf,Mapkbp1,Plk3,Myd88,Met,Acvrl1,Pml,Pim2,Ccnj,Ccl12,Tlr3,Itgav,Htr2b,Osm,Ppm1l,Lyn,Cdk5r1,Prkce,Ccnd1,Fam20c,Mlkl,Axl,Mapkapk2,Trib3,Pim3,Sla,Il1b,Atm,Acvr1b,Ccnd2,Ksr1,Mmd,Saa3,Grk3,Plk2,Bmp2 |
| 4.511e-09 | -19.22 | GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | 237 | 47 | 15632 | 1249 |
Dusp1,Rgs14,Casp3,Cish,Dusp8,Errfi1,Hhex,Socs1,Rgs3,Tnfaip3,Mvp,Irak3,Dusp6,Flrt2,Ptprj,Uchl1,Dusp5,Trib3,Il1b,Gadd45b,Flrt3,Ptpn2,Dnaja1,Spry2,Dusp2,Il6,Ppp2r5a,Dusp4,Nck1,Cdkn2d,Kat2b,Ubash3b,Irs2,Adar,Spred1,Dusp14,Cav1,Sirt1,Socs3,Trib1,Aida,Lyn,Dusp16,Igf1r,Socs7,Cdkn1a,Prkar2b |
| 4.537e-09 | -19.21 | GO_NEGATIVE_REGULATION_OF_CELL_ACTIVATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_ACTIVATION | 142 | 34 | 15632 | 1249 |
Atm,Rabgef1,H2-Eb1,Il10,Samsn1,Cd274,Pdgfb,Nfkbid,Inhba,Zc3h12a,Hmox1,Tnfsf4,Adrb2,Lyn,Irf1,Spn,Axl,Ptpn2,Bcl6,Peli1,Casp3,Ifnb1,Pde5a,Abr,Fas,Prdm1,Hlx,Il4ra,Nr1h3,Cd74,Prnp,Ubash3b,Tnfaip3,Tnfrsf14 |
| 4.626e-09 | -19.19 | GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP | 149 | 35 | 15632 | 1249 |
Traf1,Il4ra,Etv3,Usp18,Stat2,Slamf7,Pnpt1,Sp140,Ifit2,Ifit1bl1,Nlrc5,Samd9l,Ly75,Ifi44,Parp14,Ifit3b,Ak4,Dtx2,Gng4,Pcgf5,Stat1,Ebi3,Sp110,Whamm,Fscn1,Ifit3,Lad1,Ccl5,Txn1,Ifit1bl2,Leng9,Oas2,Dgka,Xaf1,Isg20 |
| 4.669e-09 | -19.18 | GSE29618_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DN | 192 | 41 | 15632 | 1249 |
Glrx,Pgk1,Trem1,Plaur,Cxcl1,Notch2,Rab20,Acsl1,Ptafr,Cdc42ep4,Trib1,Ptgs2,Rtn1,Hmox1,Fzd1,Bst1,Wars,Ext1,Pid1,Dusp6,Slc31a2,Plek,Ccr1,Ahr,Cd14,Myd88,Pilra,Slco3a1,Nlrp3,Tpi1,Cebpd,Rin2,Mgat1,Eno1,Csf3r,Timp1,Cyfip1,Casp1,Sod2,Rab32,Aoah |
| 4.732e-09 | -19.17 | KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS | MSigDB lists | KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS | 41 | 17 | 15632 | 1249 |
C3,Il13ra1,Ccl22,Il1a,Il2rg,Il18,Cxcl10,Cxcl1,Il15,Xcr1,Il1b,Tnf,Ccr1,Tnfrsf1b,Ccl5,Casp1,Ccl12 |
| 4.732e-09 | -19.17 | STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN | MSigDB lists | STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN | 41 | 17 | 15632 | 1249 |
Oas1a,Xaf1,Ifit1bl1,Ifit1bl2,Tagln,Irf7,Oas3,Sp110,Ddx60,Ifi35,Herc6,Stat1,Asap3,Oas1g,Ddx58,Dtx3l,Isg15 |
| 4.733e-09 | -19.17 | positive regulation of endopeptidase activity | biological process | GO:0010950 | 157 | 33 | 20694 | 1406 |
Uaca,Nlrc4,Jak2,Stat1,Nod1,Lyn,Cycs,Fas,Myc,Psme1,Sirt1,Malt1,Pmaip1,Nlrp3,Mefv,Syk,Psme2,Tnfsf15,Ripk2,Mul1,Fam162a,Tnf,Aim2,Ift57,Apaf1,Casp4,Tnfsf10,Bcl2l11,Stat3,Casp8,Casp1,Pml,S100a8 |
| 4.755e-09 | -19.16 | GO_POSITIVE_REGULATION_OF_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSPORT | 858 | 117 | 15632 | 1249 |
Gpr68,Hspa2,Sele,Rbpms,Micall2,Rab21,Serp1,Homer1,Tnf,Plagl2,Cd38,Cd14,Lipg,Sgk3,Aim2,Plk3,Inhba,Mmp13,Serpine1,Pdgfrb,Fzd5,Cd274,Gja1,Ccl5,H2-Eb1,Ccr1,Il1b,Htr2b,Sec24a,Il18,Nr4a3,Adora2b,Tlr3,Stap1,Pla2g4a,Itgav,Syk,Gsdmd,Clec4e,Tspo,Sdc4,Cd34,Nr1h3,Irs2,Cdk5r1,Sdc1,Stxbp1,Rhou,Slc9a1,Casp8,Cav1,Ednrb,S100a8,Ccl4,Jak2,C3,Tlr9,Mdm2,Rhoq,Rab9,P2ry12,Ifnar1,Casp1,Ehd1,Axl,Src,Sphk1,Fgr,Ddx58,Hif1a,Il1a,Lif,Hap1,Csf3,Scn1b,Pdgfb,Hcar2,Glrx,Vegfc,Bambi,Ptafr,Il12b,Cxcl10,Ptgs2,Clec5a,Scyl2,Zc3h12a,Ptger4,Nod2,Il6,Prkce,Kcnj2,Edn1,Bcl2l11,Ccl12,Ezr,Nfkbia,Angpt1,Tnfrsf14,Il4ra,Nlrp3,Abr,Rasgrp1,Sirt1,P2ry2,Ptch1,Tnfsf14,Il10,Rnf31,Clec4n,Nlgn2,Stard7,Hcls1,Cacna1d,Adrb2,Tlr2,Tnfsf4 |
| 4.757e-09 | -19.16 | regulation of receptor signaling pathway via JAK-STAT | biological process | GO:0046425 | 165 | 34 | 20694 | 1406 |
Parp14,Il10,Hcls1,Ifna6,Hdac1,Irf1,Ifna4,Parp9,Tnf,Socs1,Ptger4,Lif,Il6,Ifna2,Cenpj,Socs3,Ifna5,Notch1,Hmga2,Il12b,Il18,Ptpn2,Ifna1,Ifnb1,Osm,Crlf3,Lyn,Cav1,Cdk5r1,Il15,Clcf1,Ccl5,Cd40,Jak2 |
| 4.843e-09 | -19.15 | Chemokine signaling pathway | KEGG pathways | mmu04062 | 187 | 43 | 7931 | 713 |
Nfkb1,Stat1,Cx3cl1,Ccl3,Ccl7,Cxcl3,Akt3,Ptk2,Src,Cxcl1,Ccl9,Ccl4,Cxcl2,Pik3cd,Gng11,Gnb4,Gng12,Cxcl11,Ccr3,Nfkbib,Cxcl10,Hck,Ccl22,Stat3,Nfkbia,Gng4,Grk3,Ccl2,Fgr,Pf4,Cx3cr1,Ccl5,Ccr1,Ccl12,Ccl8,Map2k1,Cxcl9,Lyn,Jak2,Ikbkg,Xcr1,Stat2,Crkl |
| 4.843e-09 | -19.15 | Chemokine signaling pathway | KEGG pathways | ko04062 | 187 | 43 | 7931 | 713 |
Ccl5,Ccr1,Fgr,Ccl2,Cx3cr1,Pf4,Grk3,Gng4,Xcr1,Ikbkg,Jak2,Crkl,Stat2,Lyn,Cxcl9,Ccl12,Map2k1,Ccl8,Cxcl3,Ccl7,Cxcl1,Src,Akt3,Ptk2,Cx3cl1,Stat1,Ccl3,Nfkb1,Nfkbia,Stat3,Hck,Cxcl10,Nfkbib,Ccr3,Ccl22,Gng12,Cxcl11,Cxcl2,Ccl4,Ccl9,Gnb4,Gng11,Pik3cd |
| 4.935e-09 | -19.13 | regulation of interleukin-1 secretion | biological process | GO:0050704 | 47 | 17 | 20694 | 1406 |
Casp4,Fzd5,Gsdmd,Zc3h12a,Casp1,Pml,Nlrp3,Ptger4,Ifnar1,Arg2,Tnfaip3,Ripk2,Nod2,Aim2,Ccl3,Tlr2,Hk1 |
| 5.161e-09 | -19.08 | ZHENG_FOXP3_TARGETS_IN_THYMUS_UP | MSigDB lists | ZHENG_FOXP3_TARGETS_IN_THYMUS_UP | 178 | 39 | 15632 | 1249 |
Sik3,Vps54,Jarid2,Pde4b,Abtb2,Cd69,Stat4,Tlr1,Ext1,Arid5b,Ttc39b,Smc5,Etnk1,Esd,Slc37a3,Rgs1,Chd9,D16Ertd472e,Cited2,Arhgef3,Gpr18,Hivep2,Klf3,Klf6,Dock10,Errfi1,Peli1,Lrch1,Irf4,Nr3c1,Arl4a,Hif1a,Nfkbiz,Malt1,Mdfic,Tnfaip3,Zc3hav1,Samhd1,Sla |
| 5.264e-09 | -19.06 | positive regulation of T cell mediated immunity | biological process | GO:0002711 | 71 | 21 | 20694 | 1406 |
H2-Q6,Pvr,Nlrp3,Tnfsf4,Nectin2,Il1b,Arid5a,Il12b,H2-T24,Il18,Fzd5,Malt1,H2-M2,Rsad2,H2-T22,H2-Q4,H2-Q7,Tap2,Il6,H2-T10,Traf2 |
| 5.353e-09 | -19.05 | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 171 | 38 | 15632 | 1249 |
Nfkbia,Gramd1a,Ppp1r14b,Sqstm1,Pik3r5,Eno1,Mgat1,Bnip3,Nfkbie,Il18bp,Nod2,Psma6,Tpi1,Icam1,Nxf1,Gbe1,Gys1,Tnfrsf8,Etv5,P4ha1,Tnfrsf1b,Nfkb1,Gna15,Osm,Serpine1,Icosl,Ddit4,Sap30,Rnf19a,Hk2,Ldha,Slc43a3,Nfxl1,Snapc1,Sec24a,Tnip1,Fam162a,Pgk1 |
| 5.353e-09 | -19.05 | GSE19198_1H_VS_24H_IL21_TREATED_TCELL_DN | MSigDB lists | GSE19198_1H_VS_24H_IL21_TREATED_TCELL_DN | 171 | 38 | 15632 | 1249 |
Hk3,Me1,Cd83,Slamf7,Traf1,Ifih1,Fas,Micall2,Aftph,Ly75,Fchsd2,Egr2,Cd40,Ehd1,Slc7a11,Stard7,Tnfsf10,Slc29a3,Mob3b,Nr4a3,Il2rg,Naa25,Ripk2,Slc25a12,Rasgrp1,Oas2,Xaf1,Uba7,Ociad1,Slc2a6,Psme2,Itgal,Cd274,Cd86,Plek,Tor3a,Birc3,Ccl5 |
| 5.353e-09 | -19.05 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | 171 | 38 | 15632 | 1249 |
Itgal,Hopx,Tnfrsf1b,Ccl5,Rhou,Syne2,Rap1gap2,Srxn1,Sap30,Map3k8,Adrb2,Ptprj,Sema4c,Tlr3,Gfi1,Osbpl3,Slc2a1,Rhbdf2,Cst7,Casp1,Sp140,Dpy19l1,Klf6,Gsr,Gpr68,Optn,Chst11,Ctsc,Gclm,Slco3a1,Kat2b,Mcoln2,Fas,Mdfic,Rgs3,Atp2b4,Slamf7,Il15 |
| 5.480e-09 | -19.02 | GO_POSITIVE_REGULATION_OF_PROTEIN_SECRETION | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_SECRETION | 193 | 41 | 15632 | 1249 |
Ptger4,Tnfsf4,Clec5a,Jak2,Sec24a,Vegfc,Nlgn2,Il1b,Htr2b,Hcar2,Clec4n,H2-Eb1,Gja1,Il10,Cd274,Mmp13,Rasgrp1,Aim2,Il1a,Hif1a,Fgr,Nlrp3,Irs2,Il4ra,Cd34,Cd14,Clec4e,Cd38,Tnfrsf14,Src,Ezr,Tnf,Gsdmd,Ifnar1,Syk,Casp1,Serp1,Prkce,Il6,Nod2,Gpr68 |
| 5.494e-09 | -19.02 | GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_DN | 164 | 37 | 15632 | 1249 |
Ifit1bl2,Pdk3,Ifit3,Sema3c,P2ry2,Slpi,Bst1,Xkr8,Dram1,Ptgs2,Mppe1,Ddx4,Mefv,Ifit3b,Bcl2a1a,Bambi,Gca,Tnfaip2,Cd82,Trem1,Socs7,Il1b,Ifit1bl1,Rapgef5,Bcl2a1b,Sod2,Dhrs9,Slc7a11,Csf3r,Bcl6,P2ry13,Kcnj2,Igsf6,Treml2,Bcl2a1d,Tlr6,Clec4e |
| 5.503e-09 | -19.02 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | 143 | 34 | 15632 | 1249 |
Ptger4,Tlr3,Tlr9,Tnfsf4,C3,Adora2b,Ptgs2,Il12b,Tlr2,Il18,Jak2,Thbs1,Tnip1,Ccl4,Il1b,S100a8,Plek,Ccl5,Hopx,Osm,Serpine1,Pla2g7,Cx3cl1,Il15,Enpp4,Ccl3,Tnf,Ccl12,Pla2g4a,Prkce,Il6,Ccl2,Nod2,Scarf1 |
| 5.579e-09 | -19.00 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 150 | 35 | 15632 | 1249 |
Cdkn1a,Ikbke,Bcl2a1a,Jak2,Trib3,Ifi204,Dyrk2,Hmox1,Ifi203,Casp2,Sirt1,Ifi208,Ifi211,Ddit4,Mndal,Casp4,Ppp1r15a,Tnfrsf1b,Atm,Ifi207,Apaf1,Ifi214,Nupr1,Pml,Bcl2a1d,Cycs,Bnip3,Ifi205,Ifi209,Itpr1,Traf2,Bcl2l11,Bcl2a1b,Ifi213,Tnf |
| 5.597e-09 | -19.00 | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | MSigDB lists | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | 385 | 65 | 15632 | 1249 |
Gfpt1,Arf4,Lpar1,Tmod3,Il13ra1,Ell2,Itga5,Dram1,Endod1,Slc39a14,Htra1,Casp4,Sema3c,Cav1,P4ha1,Dusp14,Tspo,Plau,Papss2,Nqo1,Vcan,Mmp14,Rai14,Tmem184b,Zyx,Itgav,Rab32,Cnn2,Glrx,Ptges,Gng12,Dcbld2,Plaur,Vegfc,Plat,Sec24a,Thbs1,Clic4,Osbpl3,Lox,Nsmaf,Tgfbi,Atp10a,Fzd1,Snx2,Inhba,Ext1,Pdgfrb,Myo1b,Klf2,Gja1,Rhoc,Pdgfc,Sphk1,Tapbp,Ccnd1,Rab21,Tpst1,Serp1,Swap70,Timp1,Dusp1,Ehd1,Axl,Klf6 |
| 5.598e-09 | -19.00 | response to tumor necrosis factor | biological process | GO:0034612 | 158 | 33 | 20694 | 1406 |
Il6,Ccl4,Traf2,Tnf,Aim2,Cx3cl1,Ccl7,Ccl3,Nfkbia,Tank,Irf1,Ccl2,Birc3,Casp8,Ccl12,Gch1,Sphk1,Jak2,Acod1,Stat1,Birc2,Nfkb1,Ccl5,Fas,Ccl8,Ccl22,Tnfrsf1b,Zc3h12a,Zfp36,Cd14,Sirt1,Pid1,Ccl9 |
| 5.806e-09 | -18.96 | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN | 186 | 40 | 15632 | 1249 |
Chmp4b,Cd164,Relb,Tle3,Pfkfb3,Batf,Fcgr1,Fpr2,Hif1a,Kat2b,Cyth3,Nck1,Nupr1,Glipr2,Cebpd,Pla2g4a,Dusp2,Myc,Pdpn,Fos,Ezr,Lipe,Dusp16,Dr1,Tax1bp1,Clic4,Ier3,Map2k4,Pik3cd,Casp7,Rasgrp1,Rhou,Fabp7,Zfp36,Phlda1,Irf8,Cd86,Casp4,Serpine1,Junb |
| 5.806e-09 | -18.96 | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP | MSigDB lists | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP | 186 | 40 | 15632 | 1249 |
Parp14,Casp3,Stard5,Gbp9,Gbp4,Tapbp,Stat5a,Rapgef5,Swap70,Birc2,Rhof,Bcl6,Aff1,Crim1,Relb,Plagl2,Irf2,Mapkapk2,Cyth3,Tulp3,Hif1a,Icam1,Nfkbib,Birc3,Jdp2,Tap2,Lad1,Rel,Hopx,Casp4,Plod2,Clic4,Tmem123,Ralgds,Dusp16,Zhx2,Gfi1,Rnf19b,Cd200,Ripk2 |
| 5.818e-09 | -18.96 | GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | 62 | 21 | 15632 | 1249 |
Cd83,Cd80,Il12b,Nlrp3,Il18,Il4ra,H2-Q7,Cd55,Hlx,Tnfsf4,Ebi3,Ripk2,Ap3b1,Il12rb1,Pnp2,Il6,H2-Q6,Cd86,Hsph1,H2-Q4,Syk |
| 5.945e-09 | -18.94 | GTPase activity | molecular function | GO:0003924 | 291 | 49 | 20217 | 1400 |
Gbp2,Gng11,9930111J21Rik1,Rab32,Ifi47,Gm4841,Gnb4,Ift22,Gbp3,Rhoh,Gm4951,Gbp7,Rab21,Tgtp2,Gng12,Rhoq,Rab19,Gtpbp2,F830016B08Rik,Irgm2,Gch1,Irgm1,Rac3,Rap2c,Rhou,Rhoc,Rab10,Gng4,Gna15,Rras2,Iigp1,Gem,Mx1,Rnd1,Rab20,Tuba4a,Mx2,Rhof,Gbp2b,Gbp8,Arl4a,Rab9,Tgtp1,Gbp9,Gm12185,Igtp,Gm5431,Rnd3,Nkiras1 |
| 6.100e-09 | -18.91 | GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_DN | MSigDB lists | GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_DN | 179 | 39 | 15632 | 1249 |
Myd88,Cd80,Tle3,Marcksl1,Nr1h3,Ikzf1,Minpp1,Slc15a3,Il4i1,Mecp2,Psma6,I830077J02Rik,Cebpd,Ift57,Dusp1,Fos,Nlrc4,Serp1,Mgat1,Rhof,Tank,Cited2,Nfxl1,Acsl5,Casp7,Rcn1,Kcna3,Grina,Trim14,Phlda1,Nmi,Mmd,Rhou,Slc31a2,Eif4g2,Hsd17b12,Ppp1r15b,Dcun1d3,Sema3c |
| 6.100e-09 | -18.91 | GSE28737_WT_VS_BCL6_HET_FOLLICULAR_BCELL_DN | MSigDB lists | GSE28737_WT_VS_BCL6_HET_FOLLICULAR_BCELL_DN | 179 | 39 | 15632 | 1249 |
Ifih1,Nupr1,Lrp8,Slc28a2,Zbp1,Nod1,P2ry13,Mtus1,Rnf114,Syk,Txnrd1,Gpr68,Ccnd1,Fgl2,Ogfrl1,Optn,Stap1,Prkce,Gbp9,Slc15a3,Gbp4,Fcgr2b,Sat1,Ctsc,Clec5a,Ptgs2,Cox18,Zc3h12a,Stat1,Tfec,Ap3m2,Cd300lf,Gbp7,Tnfrsf1b,Uba7,Pla2g7,Nmi,Slc2a6,Pstpip2 |
| 6.100e-09 | -18.91 | GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | MSigDB lists | GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | 179 | 39 | 15632 | 1249 |
Trim12c,Plagl1,Hif1a,Usp25,Ddx60,Tnfaip3,Phf11c,Phf11a,Myd88,Rhbdf2,Homer1,Casp1,Phf11b,Eif2ak2,Nfkbia,Rab32,Ifit2,Crbn,Dhx58,Ifrd1,Rin2,Nfkbie,Il6,Rab9,Phf11d,Atp10a,Ap3m2,Gtpbp2,Zcchc2,Ogfr,Cnp,Plekha4,Sema3c,Csrp1,Rgl1,Hk2,Tdrd7,Trim26,Akt3 |
| 6.100e-09 | -18.91 | GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_UP | 179 | 39 | 15632 | 1249 |
Sertad3,Cdk5r1,Plagl1,Mxd1,Olfml3,Tnks1bp1,Hk3,Pdgfc,Csf3r,Usp53,Abcc5,Ifit1bl1,Nr4a1,Dusp1,Prdx5,Dusp2,Ccr3,Tnc,Mefv,Ms4a6d,Irf1,Ptgs2,Trib1,Grina,Mmp9,Hp,Kdm6b,Dgkh,Armc8,Sp110,Adam19,Fosb,Osm,Ifit1bl2,Dach1,Uba7,Slpi,Cnn3,Ube2l6 |
| 6.129e-09 | -18.91 | GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3 | MSigDB lists | GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3 | 11 | 9 | 15632 | 1249 |
Irf1,Irf7,Ifi35,Eif2ak2,Stat1,Gbp2,Irgm2,Isg20,Adar |
| 6.352e-09 | -18.87 | KEGG_CHEMOKINE_SIGNALING_PATHWAY | MSigDB lists | KEGG_CHEMOKINE_SIGNALING_PATHWAY | 172 | 38 | 15632 | 1249 |
Ccl3,Hck,Gng11,Gnb4,Fgr,Cx3cl1,Ccl22,Stat2,Cxcl14,Ccl2,Ccr3,Stat3,Ccl12,Pik3r5,Nfkbia,Cx3cr1,Xcr1,Pf4,Gng12,Ccl4,Prkx,Cxcl1,Jak2,Cxcl10,Lyn,Pik3cd,Gng4,Stat1,Ptk2,Crkl,Cxcl2,Nfkbib,Akt3,Map2k1,Nfkb1,Ikbkg,Ccl5,Ccr1 |
| 6.443e-09 | -18.86 | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 950 | 126 | 15632 | 1249 |
Pou2f2,Etv6,Med13,Slc9a1,Zeb1,Ifi211,Lmo4,Mndal,Rel,Pid1,Nfkb1,Ikbkg,Ahrr,Lhx2,Arf4,Ifi204,Tlr9,Ifnb1,Hmga1,Cited2,Ets2,Spic,Psip1,Sqstm1,Plac8,Nr4a1,Ahr,Rbl1,Ifi207,Nr1h3,Ifi214,Kat2b,Nck1,Inhba,Serpine1,Fosb,Osm,Med21,Irf7,Fzd5,Il1b,Nfkb2,Nr4a3,Ripk2,Pcgf5,Tlr3,Hdac1,Mafk,Tnfsf8,Stat3,Ifi209,Tcf4,Tnf,Klf6,Plagl2,Etv5,Ncoa7,Pbx1,Batf,Csrnp1,Met,Ifi203,Jag1,Sirt1,Plscr1,Bcl9,Il10,Irf8,Hcls1,Tnip1,Mafg,Tlr2,Adrb2,Irf1,Acvr1b,Stat1,Nod2,Myc,Il6,Ikzf1,Irf4,Edn1,Jun,Fos,Tet2,Agrn,Nlrc5,Nfkbia,Ciita,Nlrp3,Plagl1,Phip,Egr1,Atf3,Maff,Csf3,Ifi208,Pdgfb,Klf2,Nampt,Arid4a,Junb,Pf4,Cxcl10,Zc3h12a,Kdm6b,Acvrl1,Cebpd,Acvr1,Rhoq,Egr2,Nr3c1,Cd40,Ifi205,Hsph1,Ifi213,Relb,Notch1,Bmp2,Crlf3,Hif1a,Ddx58,Il1a,Lif,Hhex,Irf2 |
| 6.544e-09 | -18.84 | vascular process in circulatory system | biological process | GO:0003018 | 200 | 38 | 20694 | 1406 |
Pdgfb,Ptafr,Hif1a,Kdr,Ccl4,Abr,Sod2,Adora2a,P2ry2,Tnf,Cx3cl1,Ptgs2,Adrb2,Nr3c1,Cd38,Angpt1,Dusp5,Adora2b,Map2k1,Gch1,Ptprj,Edn1,Gja1,Htr2b,Kat2b,Cav1,Dock4,Icam1,Ahr,Htr2a,Pde5a,Plod3,Gclm,Sirt1,Il18,Ednrb,Ptk2,Gclc |
| 6.674e-09 | -18.82 | G protein-coupled receptor binding | molecular function | GO:0001664 | 292 | 49 | 20217 | 1400 |
Ccl2,Ccl8,Rapgef2,Bambi,Ptch1,Tyk2,Rtp4,Ccl9,Adrb2,Ccl3,Znrf3,Ccl7,S1pr2,Edn1,Ccl12,Marco,Grk3,Rpgrip1l,Tulp3,Cx3cl1,Fzd1,Cxcl2,C3,Ccl4,Pf4,Fcgr1,Cxcl9,Cxcl1,Stat1,Stat3,P2ry2,Homer1,Cxcl11,Cxcl10,Gna15,Adora2a,Ednrb,Cxcl14,Dnaja1,Nes,Ccl5,Cxcl3,Ccrl2,Ccl22,Hspa1a,Jak2,Prnp,Uchl1,Fpr1 |
| 6.827e-09 | -18.80 | GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_UP | MSigDB lists | GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_UP | 187 | 40 | 15632 | 1249 |
Smox,Il13ra1,Pim1,Clec4d,Ier3,Trem1,Igf1r,Hcar2,Ccr1,Rabgef1,S100a8,Dusp6,Map4k4,Hdc,Lcn2,Csf1,Pdlim7,Slpi,Rictor,Plk3,Csrnp1,Upp1,Arrdc4,Arg2,Sphk1,Dmxl2,Plau,Cd14,Pbx1,Klf7,Ahr,Mtus1,Slc2a1,Ets2,P2ry13,Micall2,Fcgr2b,Rnf24,Tra2a,Ccng2 |
| 6.827e-09 | -18.80 | GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | MSigDB lists | GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | 187 | 40 | 15632 | 1249 |
Ikzf1,Tor1aip2,Fcgr2b,Pdpn,Lipe,Csf3r,Bcl6,Batf,Pfkfb3,Fcgr1,Apaf1,Relb,Tle3,Hck,Ier2,Usp18,Cyth3,Sphk1,Psmb10,Arg2,Isg20,Zfp36,Snx2,Gja1,Irf8,Sema3c,Lgals9,P2ry2,Clcn7,Acsl5,Idi1,Ldlr,Tax1bp1,Ralgds,Dusp16,Abcc1,Larp1,Rac3,Map2k4,Pik3cd |
| 6.875e-09 | -18.80 | positive regulation of reactive oxygen species metabolic process | biological process | GO:2000379 | 106 | 26 | 20694 | 1406 |
Thbs1,Plau,Cdkn1a,Fpr2,Ass1,Il6,Klrk1,Pdgfb,Tspo,Sod2,Cxcl1,Tnf,Ptgs2,Zc3h12a,Pdgfrb,Il18,Pid1,Il1b,Klf2,Jak2,Tlr6,Acod1,Nox1,Tlr2,Icam1,Ripk3 |
| 7.159e-09 | -18.75 | I-kappaB kinase/NF-kappaB signaling | biological process | GO:0007249 | 48 | 17 | 20694 | 1406 |
Malt1,Tank,Irf1,Irak2,Tlr9,Nfkbil1,Nfkbia,Rel,Azi2,Tlr3,Ikbke,Saa3,Ripk3,Tlr2,Tifa,Ripk2,Relb |
| 7.199e-09 | -18.75 | GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_DN | MSigDB lists | GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_DN | 180 | 39 | 15632 | 1249 |
Gnb4,Rras2,Bmp2,Rhoc,Mdfic,Prdm1,Csrnp1,Mcoln2,Trim13,Cd74,Il1a,Hif1a,Ubtd2,Slc15a3,Nfkbie,Srm,Timp1,Cyfip1,Cxcl1,Tnip1,Irak2,Wdr43,Tfec,Mtdh,Dtx2,Slamf8,Srxn1,H2-Aa,Nfkbib,Slamf9,Met,Tmem176a,Egln3,Rasgrp1,Slc7a8,Hsd17b12,Gch1,Marco,Rrs1 |
| 7.199e-09 | -18.75 | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_UP | MSigDB lists | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_UP | 180 | 39 | 15632 | 1249 |
Mgat1,Bcl6,Cd40,Swap70,Apobec3,Plac8,Lipe,Fam43a,Triobp,Dusp4,Prkce,Stap1,Ctsc,Irgq,Pikfyve,Fgr,Nmral1,Irak3,Hvcn1,Slc48a1,Rel,Birc3,Slc4a7,Plek,Pou2f2,Tdrd7,Stoml1,Slc2a6,Akt3,Icosl,Il18,Ell2,Filip1l,Ripk2,Egr3,5430427O19Rik,Chd9,Clic4,Tmem123 |
| 7.199e-09 | -18.75 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_UP | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_UP | 180 | 39 | 15632 | 1249 |
Myo1b,Golga3,Rgl1,Txn1,P4ha1,Inhba,Pla2g7,Parp12,Tbc1d13,Pdss1,Gpd2,Il12b,Ebi3,Dtx2,Stip1,Il15ra,Abcc1,Keap1,Gfpt1,Fscn1,Clic4,Dnaja1,Trip10,Agrn,Txnrd1,Slc7a11,Trmt1l,Sdc2,Nqo1,Gclm,Ccl22,Rtp4,Evl,Lrp8,Crim1,Prdx1,Pilra,Cd80,Slamf7 |
| 7.199e-09 | -18.75 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_DN | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_DN | 180 | 39 | 15632 | 1249 |
Gca,Ikbke,Clic4,Ell2,Egr3,Cpeb4,Azi2,Acsl1,Grina,Clec5a,Slc43a3,Ptgs2,Pdlim7,Dusp6,Map4k4,Slc31a2,Sipa1l1,Sema3c,Tspo,Slc48a1,Gbp2,Irak3,Hvcn1,Hlx,Agtrap,Nlrp3,Fpr2,Prnp,Upp1,Sgms2,Rhoq,Egr2,Cpd,B3gnt5,Nqo1,Acvr1,Ogfrl1,Mdm2,Sod2 |
| 7.462e-09 | -18.71 | negative regulation of growth | biological process | GO:0045926 | 280 | 47 | 20694 | 1406 |
Irf8,Mndal,Notch1,Tomm70a,Plac8,Sirt1,Crlf3,Inhba,Osgin2,Cdk5r1,Tlr2,Sqstm1,Ptch1,Gja1,Jarid2,Sema4a,Ptprj,Sema3c,Gng4,Mul1,Hif1a,Acvr1b,Ptk2,Sav1,Il12b,Bcl6,Gdf15,Notch2,Cdkn2d,Nod2,Dnajb2,Ifrd1,Sema4c,Cdkn1a,Il10,Pml,Sertad3,Dcbld2,Adrb2,Acvrl1,Myd88,Tnf,Pnpt1,Mecp2,Sh3bp4,Cited2,Dcun1d3 |
| 7.519e-09 | -18.71 | HALLMARK_KRAS_SIGNALING_UP | MSigDB lists | HALLMARK_KRAS_SIGNALING_UP | 195 | 41 | 15632 | 1249 |
Gypc,Ikzf1,Tor1aip2,Abcb1a,Spry2,Gadd45g,Lif,Prdm1,Tmem176b,Traf1,Ccnd2,Gng11,Fbxo4,Bmp2,Plau,Tnfaip3,Etv5,Tnfrsf1b,Dusp6,Birc3,Psmb8,Ppp1r15a,Irf8,Slpi,Scn1b,Tmem176a,Usp12,Mmd,Inhba,Mmp9,Kif5c,Il2rg,Cxcl10,Ptgs2,Trib1,Plat,Cmklr1,Il1b,Glrx,Plaur,Dcbld2 |
| 7.524e-09 | -18.71 | MEK_UP.V1_DN | MSigDB lists | MEK_UP.V1_DN | 173 | 38 | 15632 | 1249 |
Casp8,Irf7,Snx10,Ifit1bl2,S100a8,Oas1a,Rasgrp1,Oas2,Tdrd7,Trim14,Ube2l6,Stxbp3,Ifi35,Herc6,Egr3,Oas1g,Oasl1,Kif5c,Igf1r,Prkar2b,Sp110,Rsbn1,Jak2,Oas3,Ifit1bl1,Ass1,Ift57,Minpp1,Ifi44,Myc,Usp18,Ddx58,Isg15,Ifih1,Atf3,Ddx60,Samhd1,Tap1 |
| 7.614e-09 | -18.69 | ROETH_TERT_TARGETS_UP | MSigDB lists | ROETH_TERT_TARGETS_UP | 14 | 10 | 15632 | 1249 |
Ifi44,Gpr35,Pla2g4a,Rsad2,Oasl1,Ifit1bl1,Herc6,Ifit1bl2,Ifit3b,Ifit3 |
| 7.614e-09 | -18.69 | GILMORE_CORE_NFKB_PATHWAY | MSigDB lists | GILMORE_CORE_NFKB_PATHWAY | 14 | 10 | 15632 | 1249 |
Rel,Ikbkg,Nfkb1,Nfkbia,Nfkbiz,Relb,Nfkbie,Nfkb2,Ikbke,Nfkbib |
| 7.638e-09 | -18.69 | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | 86 | 25 | 15632 | 1249 |
Cd40,H2-Q6,Traf2,Ccl12,Syk,H2-Q4,Tnf,Rsad2,Stap1,Fgr,Nlrp3,Il4ra,H2-Q7,Malt1,Nos2,Fzd5,Rasgrp1,Il12rb1,Il12b,Ptafr,Adora2b,C3,Tnfsf4,Il1b,Clcf1 |
| 7.788e-09 | -18.67 | GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_DN | MSigDB lists | GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_DN | 166 | 37 | 15632 | 1249 |
Rnd1,Socs1,Hlx,Rhoh,Slc28a2,Sav1,B4galt4,Bcl6,Gadd45b,Ifit2,Ccl12,Cxcl14,Gadd45g,Kcnj2,Cish,Aftph,Peli1,Trib1,Pim1,Acvr1b,Irf1,Cxcl10,Ifit3b,Rnf19b,Ppa1,Socs3,Tfec,Cdkn1a,Tax1bp1,Ifit3,Lcp2,Fzd5,Lap3,Plek,Ccnj,Dusp6,Zfp36 |
| 7.885e-09 | -18.66 | GO_VASCULATURE_DEVELOPMENT | MSigDB lists | GO_VASCULATURE_DEVELOPMENT | 440 | 71 | 15632 | 1249 |
Sema3c,Cav1,Sirt1,Jag1,Sema4a,Ptk2,Nox1,Egr3,Socs3,Itga5,Tnfaip2,Kdr,Tiparp,Jun,Nr4a1,Flt1,Ccl12,Syk,Itgav,Edn1,Mmp14,Pdpn,Cx3cl1,Egr1,Col18a1,Ahr,Angpt1,Cd34,Plau,Col4a2,Sgcb,Pde3b,Fzd5,Pdgfrb,Map2k1,Serpine1,Pik3r6,Junb,Gja1,Wars,Rapgef2,Nrp2,Pdgfb,Ptgs2,Tgfbi,Lox,Il18,Ptger4,Crkl,Zc3h12a,Hmox1,Vegfc,Sec24b,Thbs1,Prkx,Clic4,Ankrd17,Errfi1,Acvr1,Mdm2,Acvrl1,Sat1,Itgb8,Hif1a,Calcrl,Jmjd6,Sphk1,Prdm1,Hhex,Lif,Notch1 |
| 7.897e-09 | -18.66 | GSE14415_INDUCED_VS_NATURAL_TREG_UP | MSigDB lists | GSE14415_INDUCED_VS_NATURAL_TREG_UP | 138 | 33 | 15632 | 1249 |
Adrb2,Mppe1,Kif5c,Cd55,Tnfsf4,Rgs1,Ccl4,Chd9,Arf4,Gem,Casp4,Klf2,Gch1,Card6,Ccl5,Junb,Leng9,Plscr1,Srxn1,Fabp3,Ifih1,Nkiras1,Pttg1,Calcrl,Ddx60,Il15,Traf5,Casp1,Dusp1,Parp8,Ythdf1,Ankrd24,Nr3c1 |
| 8.017e-09 | -18.64 | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_4H_UP | MSigDB lists | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_4H_UP | 188 | 40 | 15632 | 1249 |
Gcnt2,Glrx,Rtn1,Oas1g,Ebi3,Sema4a,Tgfbi,Cacnb3,St3gal5,Flnb,Ksr1,Btg2,Vasp,Hk2,Oas1a,Pla2g7,Ppp1r15b,Tnfrsf1b,Jarid2,Rgl1,Snx10,Pde4b,Prdx1,Tap1,Ahr,Tmem176b,Marcksl1,Traf1,Ifih1,Cd74,Fcgr2b,Gsr,Mafk,Ccnd1,Aebp2,Itgav,Txnrd1,Jun,Cd302,Psmb9 |
| 8.017e-09 | -18.64 | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_UP | MSigDB lists | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_UP | 188 | 40 | 15632 | 1249 |
Cish,Gbp9,Gbp4,Dusp4,Cpd,Phlpp1,Slc16a3,Lipe,Rhof,Trp53i11,Nod1,Crim1,Gbp3,Cyth3,Nfkbib,Plscr1,Tdrd7,Hk2,Stx11,Stat4,Jdp2,Gch1,Tnfrsf1b,Nfkb1,Eno2,Igsf9,Rims3,Gna15,Cd86,Notch2,Pmepa1,Abcc1,Zc3h12a,Smox,Ptger4,Rnf19b,Nr4a3,Nsmaf,Ttc39b,Aida |
| 8.017e-09 | -18.64 | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN | 188 | 40 | 15632 | 1249 |
Cebpd,Fgl2,Nod2,Rin2,Vcan,Arhgap26,Slc15a3,Igsf6,Bcl6,Mgat1,Csf3r,Fos,Casp1,Syk,Rab32,Irak3,Hck,Hk3,Cd14,Pilra,Dmxl2,Fgr,Kctd12,Plscr1,Adap2,Irf8,Dusp6,Snx10,S100a8,Slc31a2,Ccr1,Glrx,Gca,Tnfaip2,Notch2,Siglece,Fpr1,Tlr2,Sema4a,Mtmr14 |
| 8.017e-09 | -18.64 | GSE7831_CPG_VS_INFLUENZA_STIM_PDC_1H_DN | MSigDB lists | GSE7831_CPG_VS_INFLUENZA_STIM_PDC_1H_DN | 188 | 40 | 15632 | 1249 |
Il13ra1,Kif5c,Hmox1,Ifi35,Rab20,Mthfd2,Lpar1,Ldlr,Clic4,Jak2,Sh3bgrl2,Trafd1,Ppp2r2a,Gng12,Ccr1,Birc3,Snx10,Marco,Ampd3,H2-Aa,Btg2,Hap1,Uba7,Nek6,Traf1,F11r,1600014C10Rik,Cd80,Cd14,Ciita,Cd83,Slc25a25,Mapkbp1,Ahr,Ass1,Jun,Psmb9,Cyfip1,Abcb1a,Ccnd1 |
| 8.320e-09 | -18.60 | GO_NEGATIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | 33 | 15 | 15632 | 1249 |
Dhx58,Uba7,Nmi,Ube2l6,Il10,Rel,Nlrc5,Relb,Tnfaip3,Tax1bp1,Ikbke,Rnf135,Ifih1,Isg15,Ddx58 |
| 8.320e-09 | -18.60 | PLASARI_TGFB1_TARGETS_1HR_UP | MSigDB lists | PLASARI_TGFB1_TARGETS_1HR_UP | 33 | 15 | 15632 | 1249 |
Serpine1,Gadd45b,Nr4a1,Junb,Spsb1,Gadd45g,Egr2,Il6,Spata13,Ptgs2,Cdk5r1,Ier3,Egr3,Csrnp1,Lif |
| 8.416e-09 | -18.59 | GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 330 | 58 | 15632 | 1249 |
Grina,Hmox1,Plaur,Pf4,Il1b,Acsl5,Thbs1,Tnfsf10,Serpine1,Osm,Inhba,Cd74,Il1a,Icam1,Hif1a,Traf1,Pml,Ripk3,Apaf1,Tnfaip3,Plagl2,Rnf34,Traf2,Hspa1a,Src,Hsph1,Tnf,Acvr1,Rffl,Nox1,Mmp9,Fam162a,Jak2,Cflar,Ppp2r1b,Cav1,Casp8,S100a8,Sirt1,Casp2,Phip,Mul1,Cx3cl1,Fas,Nck1,Atf3,Cdkn2d,Gclc,Psmd10,Ptpn2,Cx3cr1,Sod2,Itgav,Bcl2l11,Ifnb1,Bnip3,Ctsc,Gclm |
| 8.483e-09 | -18.59 | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_DN | MSigDB lists | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_DN | 181 | 39 | 15632 | 1249 |
Slc39a4,Parp14,Tor1aip2,Abcb1a,Dnaja1,Tcf4,Tmem184b,Slc2a1,Pde3b,Rras2,Rgs3,Ifit1,Ncoa7,Notch1,Ddx60,Socs1,Oas2,Spint2,Oas1a,Ccne1,Tshz1,Nampt,Ccr1,Gem,Fzd5,Cacybp,Marco,Znrf1,Abcc1,Ppfibp2,Dusp16,Oasl1,Socs3,Oas1g,Pim2,Pcgf5,Ptk2,Spata5l1,Dnajb4 |
| 8.483e-09 | -18.59 | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDC_DN | 181 | 39 | 15632 | 1249 |
Me1,Ahr,Bfar,Slc39a13,Upp1,Gmppb,Rars,Usp25,Hdac1,Cpd,Ift57,Nqo1,Parp14,Irgm2,Mmp14,Ccl2,Mrpl52,Psmb9,Rab32,Stat5a,Cst7,Agrn,Il15ra,Htr2b,Wdr43,Kdr,Hcls1,Chic2,Ier3,Mtmr14,Ripk2,Zc3h12a,Tdrd7,Hat1,Slc7a5,Plscr1,Fzd5,Dach1,Igsf9 |
| 8.753e-09 | -18.55 | enzyme linked receptor protein signaling pathway | biological process | GO:0007167 | 566 | 76 | 20694 | 1406 |
Ptk2,Pdgfrb,Dcp1a,Ptpn2,Lnpep,Gdf15,Arid5b,Csf1,Egr1,Irs2,Flrt2,Phip,Csrnp1,Stap1,Sipa1l1,Rhoq,Socs7,Fgr,Igf1r,Fut8,Ddit4,Acvr1,Caml,Zyx,Pml,Acvrl1,Ccl2,Angpt1,Col4a2,Myd88,Met,Nck1,Jun,Stat5a,Bambi,Kdr,Cited2,Syk,Ubash3b,Vegfc,Rgs14,Axl,Mapkapk2,Pdgfc,Sirt1,Tiparp,Arf4,Nr4a3,Cdk5r1,Ppm1l,Inhba,Lyn,Lcp2,Jak2,Flrt3,Casp3,Adgre4,Plat,Crkl,Ptprj,Bmp2,Stoml1,Hap1,Stat3,Gcnt2,Hck,Src,Nrp2,Rapgef2,Mvp,Lox,Fos,Flt1,Acvr1b,Lif,Pdgfb |
| 8.900e-09 | -18.54 | GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_DN | 174 | 38 | 15632 | 1249 |
Ube2l6,Trim14,Lnpep,Psmb8,Irf7,Lap3,Tnfsf14,Arf4,Vrk2,Trafd1,Acp2,Plaur,Tmod3,Zc3h12a,Ldha,Rnf19b,Etnk1,Hmgcs1,Arid5b,Trib1,Ptgs2,Myc,Nr3c1,Rab21,Dhx58,Cox17,Ogfrl1,Rapgef5,Tnf,Ets2,Zbp1,Adar,Pilra,Plagl2,Irak3,Marcksl1,Mxd1,Irf2 |
| 8.900e-09 | -18.54 | GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 174 | 38 | 15632 | 1249 |
Eno2,Birc3,Igsf9,Mov10,Rims3,Irf7,Wdr59,Phlda1,Smox,Herc6,Oasl1,Ptgir,Cacnb3,Nr4a3,Pkp4,Pmepa1,Abcc1,Zhx2,Spsb1,Stat5a,Insl6,Slc16a3,Homer1,Arid5a,Ets2,Tcf4,Tnfsf8,Fchsd2,Ifi44,Dhx58,Gadd45g,Mxd1,Atp11a,Tulp3,Ifih1,Ifit1,Rab3ip,Plagl2 |
| 8.900e-09 | -18.54 | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_UP | 174 | 38 | 15632 | 1249 |
Rnaset2a,Klf2,Oas2,Parp12,Pla2g7,Zfp36,St3gal5,Ddit4,Ube2l6,Ier3,Cd200,Sp110,Fam162a,Rnaset2b,Ralgds,Prkx,Cxcl1,H2-Q6,Arid5a,Casp1,Flt1,Nfkbia,Plac8,H2-Q4,Ifi44,Il6,Ccnd2,Tmem176b,H2-Q7,Ier2,Tap1,Hck,Rhoc,Mark2,Pdgfc,Tnfrsf14,Zbp1,Cd14 |
| 9.058e-09 | -18.52 | AACTTT_UNKNOWN | MSigDB lists | AACTTT_UNKNOWN | 1691 | 198 | 15632 | 1249 |
Bcl2a1a,Tnfsf10,Ptgs2,Tlr1,Nfkbid,Gch1,Crim1,Ube2e1,Apba1,Dtx3l,Sphk1,Nr3c1,Rhoq,Bcl2a1d,Axl,Igf1r,Prkar2b,Irf1,Bcl9,Ube2e2,Dach1,Il10,Lrp8,Tmtc2,Prnp,Sass6,Spry2,Pdpn,Myc,Nfkbia,Jun,Nfkb2,Ppp2r2a,Phf6,Tmem229b,Gpr85,Nrp2,Tmeff1,Arl5b,Inhba,Sh3bp4,Eya4,Pde4b,Fosb,Rgs3,Etv5,Klf8,D1Ertd622e,Tlk2,Klf6,Tnf,Traf2,Bcl6,P2ry13,Rap2c,Pmepa1,Ptk2,Sema4c,Trib1,Slc9a1,Ppp4r2,Med13,Mmd,Etv6,Gem,Cep350,Extl2,Tle3,Cyth3,Arl4a,Gmppb,Vcan,Cept1,Ifnb1,Bcl2a1b,Rapgef5,D16Ertd472e,Casz1,Dnaja1,Thbs1,Clic4,Zhx2,Sec24b,Rnf19b,Dnaja2,Lox,Pdgfb,Rilpl1,Csf3,Slc4a7,Jarid2,Sesn3,Daam1,Notch1,Hlx,Hif1a,Socs1,Slco3a1,Cish,Fchsd2,Egr2,Zfp800,Src,Hsph1,Gypc,Actb,Cacna1d,Trem1,Agpat4,Adrb2,Akt3,Cysltr2,Jag1,Cd69,Hat1,Psat1,Lnpep,Ubr4,Ptch1,Htr2a,Atp2b4,Pgs1,Atf3,Plagl1,Kcnj2,Igsf6,Chst11,Ncoa5,Flrt3,Fos,Dock4,Pcdh7,Kitl,Snn,Htr2b,St3gal1,Gng4,Pcgf5,Nr4a3,Sap30,Ext1,Reps1,Car13,Mmp13,Ppp2r3a,Ccr1,Hsd17b12,Cdyl,Brwd3,Gja1,Cd274,Fzd5,Sav1,Gnb4,Ube2f,Pbx1,Stau1,Olfml3,Tsku,Prdm1,Csrnp1,Slc39a13,Tab2,Stat3,Ntng2,Cp,Mecp2,Rbpms,Abcc5,Homer1,Tcf4,Rbms1,Ust,Col27a1,Lhx2,Dgkh,Egr3,Cacnb3,Tnip3,Rnf145,Zeb1,Atxn7l1,Usp12,Egln3,Syne2,Stx6,Rnf14,Rel,Pid1,Cd34,Sdc4,Nek6,Bcor,Usp25,Nxf1,Pikfyve,Mid1,Ift57 |
| 9.126e-09 | -18.51 | REACTOME_TRIF_MEDIATED_TLR3_SIGNALING | MSigDB lists | REACTOME_TRIF_MEDIATED_TLR3_SIGNALING | 69 | 22 | 15632 | 1249 |
Tab2,Map2k4,Tlr3,Ripk2,Mapkapk2,Ripk3,Nod1,Zbp1,Ikbke,Irak2,Ppp2r1b,Nfkb2,Fos,Jun,Irf7,Map2k1,Nfkbia,Dusp6,Ikbkg,Nod2,Dusp4,Nfkbib |
| 9.295e-09 | -18.49 | QI_HYPOXIA | MSigDB lists | QI_HYPOXIA | 132 | 32 | 15632 | 1249 |
Dusp1,P4ha2,Bcl2l11,Homer1,Slc2a1,Bnip3,Gpr35,Triobp,Ccng2,Gbe1,Jmjd6,Cdc42ep2,Hk1,Gch1,P4ha1,Higd1a,Plod2,Plekha2,Sap30,Ddit4,Ampd3,Rnf19a,Fzd1,Hk2,Egln3,Hmox1,Il13ra1,Ier3,Lox,Whamm,Pfkl,Cdkn1a |
| 9.400e-09 | -18.48 | GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_DN | MSigDB lists | GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_DN | 189 | 40 | 15632 | 1249 |
Hopx,Casp8,Lmo4,Eif4g2,Slc4a7,Ppp1r15b,Ccrl2,G3bp2,Kctd12,Tmem176a,Il18rap,Uba7,H2-Aa,Serpinb9,Ptger4,Casp7,Mmp9,Trafd1,Bcl2a1a,Vcam1,Cd82,Cyfip1,Psmb9,Parp8,Bcl2a1b,Rin2,Fgl2,Bcl2a1d,Slc44a1,Spata13,Icam1,Nxf1,St3gal6,Prdm1,Gbp2,Mdfic,Relb,Rnf34,Crlf3,Gpc1 |
| 9.400e-09 | -18.48 | GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP | MSigDB lists | GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP | 189 | 40 | 15632 | 1249 |
Slc7a5,Eef1e1,Eif4g2,Nfkb1,Rnf14,Lcp2,Tnfsf14,Gem,Rrs1,Cflar,Bcl2a1a,Snapc1,Adam19,Il1b,Pgk1,Wdr43,Nfil3,Kdm6b,Dusp5,Cd200,Mthfd2,Acsl1,Irf4,Cycs,Pnp2,Egr2,Cox17,Rsad2,Bcl2a1d,Hivep2,Ezr,Tnf,Bcl2a1b,Rras2,Prdx1,Dusp14,Plagl2,Ahr,Atf3,Ccnd2 |
| 9.490e-09 | -18.47 | DAPIN | interpro domains | IPR004020 | 27 | 13 | 19984 | 1430 |
Ifi207,Ifi213,Ifi208,Ifi204,Ifi209,Ifi211,Ifi214,Mefv,Aim2,Mndal,Ifi205,Ifi203,Nlrp3 |
| 9.501e-09 | -18.47 | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP | 204 | 42 | 15632 | 1249 |
Casp8,Mndal,Klf2,Gch1,Birc3,Ifi203,Rap1gap2,Slc25a12,Stat4,Slc39a14,Ifi208,Piezo1,Ifi211,Mcm6,Ifi204,Gfi1,Sp110,Hcls1,Cflar,Ifi205,Rbbp8,Ifi209,H2-Q6,Sp140,Apobec3,P4ha2,Ifi213,Ehd1,Cenpe,H2-Q4,Hdac1,Optn,Fut8,Arg2,Traf1,Tpx2,Ifi214,Kat2b,H2-Q7,Cd38,Ifi207,Batf |
| 9.769e-09 | -18.44 | GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | 75 | 23 | 15632 | 1249 |
Mmp14,Pnp2,Il6,Rasgrp1,Ap3b1,Il12rb1,Syk,Axl,Pik3r6,Cd86,Cd80,Il15,Cd83,Il1b,Ripk2,Egr3,Tnfsf4,Hlx,Prdm1,Il12b,Il4ra,Nlrp3,Cd74 |
| 9.826e-09 | -18.44 | glial cell activation | biological process | GO:0061900 | 38 | 15 | 20694 | 1406 |
Tlr9,Nampt,Casp1,Fpr2,Cx3cr1,Tlr1,Il1b,Tlr3,Jak2,Tlr6,Jun,Tlr2,Adora2a,Tnf,Cx3cl1 |
| 9.873e-09 | -18.43 | RIG-I-like receptor signaling pathway | KEGG pathways | mmu04622 | 68 | 23 | 7931 | 713 |
Il12b,Nfkbib,Cxcl10,Tnf,Ifna5,Irf7,Azi2,Ifna4,Nfkbia,Ikbkg,Tank,Isg15,Ifna6,Casp8,Ikbke,Traf2,Ifna1,Ddx58,Ifih1,Dhx58,Ifna2,Nfkb1,Ifnb1 |
| 9.873e-09 | -18.43 | RIG-I-like receptor signaling pathway | KEGG pathways | ko04622 | 68 | 23 | 7931 | 713 |
Nfkb1,Ifna2,Ifna1,Ddx58,Ifih1,Dhx58,Isg15,Traf2,Ikbke,Casp8,Nfkbib,Cxcl10,Tnf,Nfkbia,Ifna5,Irf7,Ifnb1,Tank,Ifna6,Il12b,Ifna4,Ikbkg,Azi2 |
| 9.980e-09 | -18.42 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_DN | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_DN | 182 | 39 | 15632 | 1249 |
Casp1,Cst7,Bcl2a1b,Gadd45g,Bcl2a1d,Lztfl1,Mecp2,Fgl2,Cish,Abcb1a,Sat1,Gbp3,Icam1,Hif1a,Kat2b,Tpi1,Aim2,Gbp2,Mdfic,Ripk3,Casp4,Vps54,Txn1,Slc4a7,Il18rap,Il12rb1,Tlr1,St3gal5,Ksr1,Csf1,Ttc39b,Ptafr,Socs3,Gfi1,Glrx,Pmepa1,Il15ra,Rgs1,Bcl2a1a |
| 9.980e-09 | -18.42 | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_UP | MSigDB lists | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_UP | 182 | 39 | 15632 | 1249 |
Ifit1bl1,Crbn,Gbp4,Nat2,Gbp9,Rffl,Cish,Ikzf1,B3gnt5,Mllt6,Cdkn2d,Rhoh,Nck1,Slco3a1,Sell,Sgcb,Gbp2,Ripk3,Daxx,Tuba4a,Lnpep,Ifit1bl2,Mthfd1l,Gbp7,Casp8,Lgals9,Rasgrp1,Snx2,Rnf19a,Slc25a12,Cd200,Dyrk2,Il2rg,Mppe1,Cmklr1,Pgk1,Sp110,Frmd6,Igf2bp2 |
| 1.018e-08 | -18.40 | cellular response to peptide | biological process | GO:1901653 | 229 | 41 | 20694 | 1406 |
Cav1,Irs2,Nod2,Kat2b,Nod1,Nfkb1,Rab10,Nr4a3,Icam1,Socs7,Igf1r,Stat1,Phip,Jak2,Tlr6,Rhoq,Vcam1,Trib3,Akt3,Ptk2,Itga4,Mdm2,Ptpn2,Il18,Sirt1,Ripk2,Stat5a,Cyfip1,Pde3b,Fpr2,Nr4a1,Fcgr2b,Timeless,Slc9a1,Casp4,Adrb2,Prnp,Agtrap,Irf1,Stat3,Src |
| 1.019e-08 | -18.40 | regulation of nitric oxide biosynthetic process | biological process | GO:0045428 | 67 | 20 | 20694 | 1406 |
Sod2,Cav1,Tspo,Tlr2,Icam1,Tnf,Ptgs2,Klf2,Klrk1,Atp2b4,Il6,Tlr6,Jak2,Il10,Cx3cr1,Ass1,Il1b,Cd34,Acp5,Zc3h12a |
| 1.026e-08 | -18.40 | GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN | 197 | 41 | 15632 | 1249 |
Ncoa7,Gbp2,Gnb4,F10,Intu,P2ry14,Psmb10,Gbp3,Itga4,H2-Q7,Nupr1,Fgl2,Parp14,Gbp4,Gbp9,Cp,Znfx1,H2-Q6,Itpr1,H2-Q4,Plac8,Ifit2,Syk,Cd300lf,Aida,Irf1,Slamf8,Il2rg,Ifit3b,Etnk1,Dennd2a,Bst1,Uba7,Tdrd7,Ube2l6,Tifa,Lgals9,Ifit3,Irf8,Gbp7,Hdc |
| 1.026e-08 | -18.39 | LIM_MAMMARY_STEM_CELL_UP | MSigDB lists | LIM_MAMMARY_STEM_CELL_UP | 434 | 70 | 15632 | 1249 |
Clmp,Lrp4,Gypc,Phldb1,Axl,Tpst1,Tcf4,Egr2,Dock10,Fgl2,Rbpms,Prdm1,Malt1,Sphk1,Slco3a1,Upp1,Icam1,1600014C10Rik,Gnb4,Tsku,Etv5,Gja1,Dusp6,Dmwd,Plekha4,Cnp,Flrt2,Antxr1,Pdlim7,Nrp2,Ext1,Ptgs2,Thbs1,Pcdh7,Il1b,Dcbld2,Bcl2l11,Tagln,Myc,Pdpn,Il6,Cxcl14,Vcan,Bcor,Col18a1,Fas,Prnp,Ccnd2,Gng11,Cdc42ep2,Sgcb,Col4a2,Rnd3,Spred1,Dcun1d3,Ednrb,Gem,Cav1,Sema3c,Htra1,Akt3,Pla2g7,Jag1,Egr3,Rcsd1,Itga9,Lrrc8c,Cdkn1a,Nlgn2,Agpat4 |
| 1.027e-08 | -18.39 | PYRIN | pfam domains | PF02758 | 27 | 13 | 18711 | 1348 |
Ifi205,Ifi209,Ifi207,Ifi204,Ifi211,Ifi203,Aim2,Ifi213,Mndal,Ifi214,Ifi208,Mefv,Nlrp3 |
| 1.027e-08 | -18.39 | positive regulation of alpha-beta T cell differentiation | biological process | GO:0046638 | 49 | 17 | 20694 | 1406 |
Malt1,Irf1,Il18,Ikzf1,Cd83,Tnfsf4,Nlrp3,Il6,Syk,Nfkbiz,Socs1,Ap3b1,Ripk2,Hlx,Il4ra,Il2rg,Nfkbid |
| 1.056e-08 | -18.37 | CROONQUIST_STROMAL_STIMULATION_UP | MSigDB lists | CROONQUIST_STROMAL_STIMULATION_UP | 53 | 19 | 15632 | 1249 |
Ier2,Nupr1,Pim2,Tgfbi,Ier3,Lox,Fscn1,Cxcl1,Ccl4,Rgs1,Nfkbia,Dusp1,Ppp1r15a,Fos,Serpine1,Fosb,Il6,Vcan,Cxcl2 |
| 1.056e-08 | -18.37 | GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 332 | 58 | 15632 | 1249 |
Spred1,Dusp14,Adar,Ubash3b,Kat2b,Irs2,Nck1,Cdkn2d,Dusp4,Spry2,Dusp2,Il6,Ppp2r5a,Psmd10,Ptpn2,Dnaja1,Gadd45b,Flrt3,Dusp16,Igf1r,Cdkn1a,Socs7,Prkar2b,Trib1,Aida,Lyn,Socs3,Sirt1,Psme2,Cav1,Psmb8,Rgs3,Mvp,Tnfaip3,Irak3,Socs1,Psmb10,Ube2e1,Psme1,Hhex,Pml,Errfi1,Psma6,Casp3,Dusp8,Cish,Rgs14,Psmb9,Dusp1,Src,Il1b,Trib3,Ptprj,Dusp5,Uchl1,Psmb6,Flrt2,Dusp6 |
| 1.057e-08 | -18.37 | regulation of receptor signaling pathway via STAT | biological process | GO:1904892 | 170 | 34 | 20694 | 1406 |
Ifna1,Ptpn2,Il18,Il12b,Hmga2,Notch1,Cd40,Jak2,Crlf3,Cav1,Lyn,Osm,Ifnb1,Ccl5,Clcf1,Il15,Cdk5r1,Hdac1,Ifna6,Irf1,Il10,Parp14,Hcls1,Il6,Lif,Ptger4,Ifna2,Socs3,Cenpj,Ifna5,Parp9,Ifna4,Tnf,Socs1 |
| 1.065e-08 | -18.36 | KIM_HYPOXIA | MSigDB lists | KIM_HYPOXIA | 25 | 13 | 15632 | 1249 |
Tpi1,Ldha,Icam1,Gys1,Eno2,Serpine1,Slc2a1,Jun,Il6,Ampd3,Bnip3,Sap30,Ccng2 |
| 1.067e-08 | -18.36 | negative regulation of neuron death | biological process | GO:1901215 | 247 | 43 | 20694 | 1406 |
Itpr1,Jak2,Slc7a11,Ncoa7,Cd200,Nr4a3,Clcf1,Hmox1,Optn,Btg2,Tnfrsf1b,Sirt1,Axl,Chmp4b,Il6,Nes,Hif1a,Mt1,Hsph1,Cpeb4,Cd34,Csf3,Stat3,Rel,Csf1,Ccl5,Gclm,Gclc,Mecp2,Stxbp1,Kdr,Sod2,Jun,Fzd1,Cx3cl1,Adora2a,Hdac1,Angpt1,Cx3cr1,Il10,Ccl12,Map2k4,Abcc1 |
| 1.101e-08 | -18.32 | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_UP | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_UP | 190 | 40 | 15632 | 1249 |
Kctd12,Tmem176a,Uba7,Il18rap,Il12rb1,Pla2g7,Gem,Lmo4,Irf8,Hopx,Ccl5,Tnfrsf1b,Psmb8,Cd82,Adam19,Vcam1,Bcl2a1a,Nsmaf,Map3k8,Lyn,Kcna3,Mmp9,Ell2,Casp7,Bcl2a1d,Fgl2,Rin2,Il4i1,Bcl2a1b,Sod2,Plac8,Notch1,Rgs3,Gpc1,St3gal6,Icam1,Mapkapk2,Tmem176b,Psme1,Hhex |
| 1.127e-08 | -18.30 | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN | MSigDB lists | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN | 48 | 18 | 15632 | 1249 |
Adora2a,Ifnb1,Tuba4a,Axl,Serpine1,Jun,Gem,Traf2,Plk2,Ccl4,Ralgds,Rras2,Cflar,Il15,Ahr,Vegfc,Arl4a,Il2rg |
| 1.160e-08 | -18.27 | response to interferon-alpha | biological process | GO:0035455 | 24 | 12 | 20694 | 1406 |
Ifitm1,Myc,Plscr1,Axl,Ifit3,Tgtp1,Ifnar1,Ifit1,Ifit2,Eif2ak2,Ifi204,Adar |
| 1.172e-08 | -18.26 | GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_DN | MSigDB lists | GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_DN | 183 | 39 | 15632 | 1249 |
Rgs3,Tal2,Cd80,Batf,Il4ra,St3gal6,Nfkbiz,Stk40,Errfi1,Dusp2,Carhsp1,Il6,Syk,Bcl2l11,Nr4a1,Hivep2,Nfkbia,Ehd1,Ezr,Dusp16,Plaur,Thbs1,Tnip1,Cxcl1,Cdc42ep4,Odc1,Adora2b,Pim2,Socs3,Ell2,Cxcl2,Ccrl2,Csf3,Slc7a5,Rrs1,Fosb,Hopx,Plk2,Nfkb1 |
| 1.172e-08 | -18.26 | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_DN | MSigDB lists | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_DN | 183 | 39 | 15632 | 1249 |
Asns,Slfn4,Casp4,Atp6v1d,Sik3,Abtb2,Stat4,Rnf19a,Cd69,Caml,Trib3,Ddx4,Pcgf5,Lacc1,Tagap,Il15ra,Gfi1,Cdkn1a,Jak2,Snapc1,Slfn3,Cflar,Bcl2a1a,Clic4,Rbbp8,Gadd45b,Bcl2a1b,4932438A13Rik,Nfkbie,Bcl2a1d,Sat1,Edn1,Tnfsf8,Ifih1,Nfkbil1,Egr1,Rgs3,Myd88,Pde3b |
| 1.172e-08 | -18.26 | GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_UP | MSigDB lists | GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_UP | 183 | 39 | 15632 | 1249 |
Vasp,Slc7a5,Phlpp2,Lcp2,Daam1,Rrs1,Eif4g2,Eno2,Rnf14,Nfkb1,Gfi1,Wdr43,Bcl2a1a,Cflar,Snapc1,Fscn1,Adam19,Serpinb2,Ccl4,Nsmaf,Mthfd2,Ier3,Egr3,Kdm6b,Cd200,Dusp5,Bcl2a1d,Irf4,Cycs,Egr2,Homer1,Zyx,Hivep2,Bcl2a1b,Ahr,Prdx1,Rras2,Traf1,Atf3 |
| 1.175e-08 | -18.26 | regulation of B cell activation | biological process | GO:0050864 | 131 | 29 | 20694 | 1406 |
Samsn1,Bcl6,Parp3,Cd74,Mmp14,Casp3,Cd40,Ahr,Clcf1,Fas,Tnfaip3,Lyn,Irs2,Nod2,Peli1,Slamf8,Cd38,Prdm1,Tlr9,Fcgr2b,Tnfsf4,Cdkn1a,Il10,Bst1,Il6,Atm,Syk,Stat5a,Il2rg |
| 1.189e-08 | -18.25 | myeloid cell differentiation | biological process | GO:0030099 | 239 | 42 | 20694 | 1406 |
Csf3,Batf,Ikzf1,Plscr1,Src,Clec5a,Tnfsf9,Pml,Ccr1,Snx10,Casp8,Hcls1,Cited2,Arid4a,Jun,Tmod3,Batf2,Tnf,Fam20c,Cd300lf,Bcl6,Junb,Sirt1,Ptpn2,Irf4,Tet2,Irf8,Hhex,Prkx,Tcea1,Klf2,Casp3,Jak2,Stap1,Relb,Jmjd6,Notch2,Lyn,Tlr2,Il15,Adar,Csf1 |
| 1.216e-08 | -18.22 | DAZARD_RESPONSE_TO_UV_NHEK_DN | MSigDB lists | DAZARD_RESPONSE_TO_UV_NHEK_DN | 284 | 52 | 15632 | 1249 |
Adrb2,Ptk2,Dtx2,Dyrk2,Stard7,Chd9,Ldlr,Cep350,Casp8,Ccne1,Nfkb1,Spen,Trim13,Phip,Pikfyve,Nck1,Klf7,Aff1,Ahr,Gclc,Dock4,Tiparp,Morc3,Hivep2,Rapgef5,Phlpp1,Rin2,Cnot4,Myc,Bbx,Adora2b,Arid5b,Smc5,Fndc3a,Vegfc,Zhx2,Keap1,Rsbn1,Flrt2,Rrs1,Cdyl,Jarid2,Rapgef2,Ddit4,Mtus1,Birc2,N4bp1,Tlk2,Mecp2,Cers6,Cebpd,Nr3c1 |
| 1.228e-08 | -18.22 | FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS | MSigDB lists | FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS | 268 | 50 | 15632 | 1249 |
Rgl1,Gch1,Gdf15,Flrt2,Plk2,Ascc3,Serpine1,Icosl,Btg2,Snx2,Dgka,Rnf19b,Tlr3,Fcho2,Bcl6,Stat3,Fchsd2,Mdm2,Plk3,Prdm1,Lif,Pml,Nupr1,Apaf1,Tsku,Mfap3l,Lnpep,Pstpip2,Csf1,Slc9a1,Pou2f2,Stx6,Dram1,Itpkc,Trib1,Ier3,Cflar,Cd82,Cdkn1a,Tet2,Tgs1,Vcan,Atf3,Fas,Gbe1,Slc30a1,Gpc1,Dusp14,Ppfibp1,Zc3hav1 |
| 1.239e-08 | -18.21 | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_UP | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_UP | 176 | 38 | 15632 | 1249 |
Ahr,Tap1,Hck,Daxx,Zbp1,Slamf7,Slco3a1,Klf8,Ier2,Prdm1,Mlkl,Cdyl2,Dusp2,Zyx,Rhof,Arid5a,Cyfip1,Tet2,Apobec3,Srm,Cenpe,Ehd1,Nlrc5,Keap1,Ldlr,Ptafr,Mcm6,Slc43a3,Trib1,Hmox1,Oas1g,Mtmr14,Ebi3,Rasgrp1,Oas1a,Slc7a5,Hk1,Ccne1 |
| 1.287e-08 | -18.17 | GSE38304_MYC_NEG_VS_POS_GC_BCELL_UP | MSigDB lists | GSE38304_MYC_NEG_VS_POS_GC_BCELL_UP | 191 | 40 | 15632 | 1249 |
Dyrk2,Ptgir,Egr3,Ifit3b,Nr4a3,Frmd6,Pmepa1,Card6,4930523C07Rik,Pde4b,Birc3,Irf7,Ptch1,Gbp7,Cenpj,Ifit3,Arl5b,Med13,St3gal5,Bcl9,Cnn3,Trim56,Cdkn2d,Marcksl1,Il4ra,Zfp281,Sgk3,Myo10,Atp11b,Slfn5,Rab3ip,Ifnar1,Gypc,Ets2,Egr2,Nr3c1,Ccng2,Cers6,Acvrl1,Lztfl1 |
| 1.287e-08 | -18.17 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | 191 | 40 | 15632 | 1249 |
Ttc39c,Dnaja1,Slc2a1,Cx3cr1,Bcl2a1b,Chst11,Bcl2a1d,Stap1,Rab19,Etv5,Slc28a2,Plau,Cd80,Plk2,Samsn1,Osm,Ttc9c,Ccne1,Sh3bp4,Ccrl2,Pde7b,Rap1gap2,Tmeff1,Akt3,Phlda1,Noc4l,Rcn1,Kcna3,Dnajb4,Spata5l1,Sema4c,Ptk2,Ptgir,Esd,Dcbld2,Pgk1,Cdkn1a,Htr2b,Bcl2a1a,Cd300lf |
| 1.287e-08 | -18.17 | GO_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 191 | 40 | 15632 | 1249 |
Gsdmd,Axl,Ifi213,Eif2ak2,Fos,Ifi209,Slc2a1,Jun,Ifi205,Tnc,Slc39a4,Mdm2,Atf3,Upp1,Icam1,Sphk1,Ifi214,Il15,Ifi207,Ccl5,Ccne1,Asns,Ppp1r15a,Cav1,Mndal,Wdr59,Ifi211,Ifi208,Sirt1,Fzd1,Ifi203,Cpeb4,Max,Hmox1,Zc3h12a,Adora2b,Ifi204,Pim1,Lyn,Cdkn1a |
| 1.299e-08 | -18.16 | MODULE_6 | MSigDB lists | MODULE_6 | 376 | 63 | 15632 | 1249 |
Nqo1,Cpd,Ctsc,Zyx,Jun,Ets2,Cited2,Tspan3,Fos,Ccl12,Nr4a1,Gadd45b,Gclc,Cd34,Il4ra,Cx3cl1,Sdc1,Egr1,Atf3,Slpi,Cnn3,Lcn2,Lmo4,Gem,Cav1,Tnfrsf1b,S100a8,Cdkn1a,Ldlr,Rgs1,Tnfaip2,Ier3,Lyn,Ell2,Hspa2,Rbpms,Ccnd1,Tnc,Birc2,Bcl6,Mtus1,Mvp,Tnfaip3,Crim1,Cd14,Nupr1,Plk3,Ch25h,Maff,Dgka,Ddit4,Fosb,Pdgfrb,Ppp1r15a,Gdf15,Ccl5,Dusp6,Junb,Tnfsf10,Tgfbi,Dusp5,Cd55,H2-Ab1 |
| 1.310e-08 | -18.15 | ELVIDGE_HIF1A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_TARGETS_DN | 82 | 24 | 15632 | 1249 |
Nr3c1,Bnip3,Fos,Slc2a1,Cited2,P4ha2,Pfkfb3,Gys1,Gbe1,Egln3,Hk2,Maff,Pdgfb,Isg20,Cav1,Eno2,P4ha1,Gja1,Fam162a,Vegfc,Glrx,Pgk1,Ak4,Lox |
| 1.341e-08 | -18.13 | GO_PHOSPHORYLATION | MSigDB lists | GO_PHOSPHORYLATION | 1141 | 144 | 15632 | 1249 |
Il2rg,Map3k8,Il18,Trib3,Adora2b,Psmb6,Ripk2,Tlr3,St3gal1,Crkl,Pgk1,Htr2b,Il1b,Inpp1,Irak2,Ikbke,Kitl,Osm,Map2k1,Pdgfrb,Ccl5,Dusp6,Il12rb1,Rapgef2,Psmb10,Tab2,Plk3,Irak3,Sgk3,Tnf,Stat5a,Tlk2,Mecp2,Stat3,Cycs,Map2k4,Lyn,Trib1,Pim2,Tlr9,Ptk2,Dgkh,Vrk2,Jak2,Sik3,Cav1,Nfkb1,Ikbkg,Hk1,Atm,Mmd,Rictor,Psme2,Papss2,Mul1,Irs2,Cdk5r1,Pikfyve,Tpi1,Nek6,Hk3,Spred1,Cd80,Pim3,Il15,Sqstm1,Itgav,Syk,Morc3,Eif2ak2,Dusp4,Ak4,Pim1,Scyl2,Ldha,Dusp5,Ptger4,Cmpk2,Prkx,Pik3r6,Cd86,Plk2,Map4k4,Hk2,Dgka,Tyk2,Pdgfb,Sphk1,Fgr,Pml,Lif,Psme1,Mdfic,Hck,Ripk3,Daxx,Bmp2,Nod1,Eno1,Psmb9,Lipe,Src,Axl,Acvrl1,Psma6,Stk40,Mlkl,Acvr1,Ccnd1,Dbnl,Pik3cd,Tlr2,Acvr1b,Dck,Itpkc,Dyrk2,Etnk1,Igf1r,Pfkl,Kdr,Fam20c,Ccne1,Eno2,Pdk3,Psmb8,Met,Rasgrp1,Akt3,Ksr1,Ppm1l,Sgms2,Mapkapk2,Angpt1,Mark2,Pfkfb3,Ciita,Psmd10,Pik3r5,Ccl12,Flt1,Map3k6,Nod2,Myc,Prkce |
| 1.375e-08 | -18.10 | GO_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | MSigDB lists | GO_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 184 | 39 | 15632 | 1249 |
Pdgfrb,Klf2,Ppp1r15b,Txn1,Il18rap,Sirt1,Nr4a3,Ldha,Hmox1,Kdm6b,Hp,Il1b,Jun,Fos,Traf2,Txnrd1,Sod2,Dusp1,Src,Klf6,Prdx5,Gsr,Nqo1,Il18bp,Mdm2,Il6,Edn1,Pla2g4a,Cycs,Casp3,Bnip3,Sphk1,Sdc1,Hif1a,Plk3,Fas,Tnfaip3,Olr1,Prdx1 |
| 1.431e-08 | -18.06 | GO_LEUKOCYTE_CHEMOTAXIS | MSigDB lists | GO_LEUKOCYTE_CHEMOTAXIS | 101 | 27 | 15632 | 1249 |
Cxcl2,Pdgfb,Il10,Pde4b,Ccr1,S100a8,Ccl5,Ednrb,Trem1,Pf4,Il1b,Ccl4,Itga9,Pik3cd,Cxcl10,Edn1,Ccl2,Il6,Csf3r,Cx3cr1,Flt1,Sbds,Syk,Ccl12,Ccl3,Ccl22,Cx3cl1 |
| 1.444e-08 | -18.05 | small molecule binding | molecular function | GO:0036094 | 2406 | 235 | 20217 | 1400 |
Me1,Phgdh,Gpsm2,Plk2,Sik3,Dnaja2,Gsr,Atp13a1,Dgka,Katna1,Sirt1,Nlrc5,Chd9,Trip13,Ddx4,Abcb1a,Nod2,Atp11a,Lyn,Prkce,Arl5b,Irgm1,Dyrk2,Rac3,Ptk2,Atp2b4,Hcar2,Ksr1,Oas3,Sod2,Cenpe,Pikfyve,Slfn8,Fam20c,P2ry2,Igf1r,Arl5c,Gk,Hspa2,Itpr1,Src,Acvr1b,Adap2,Hdc,Sesn3,Mx1,Iigp1,Rras2,Adgb,Rap2c,Irgq,Sgk3,Lcn2,Plod2,Swap70,Pik3cd,Hsph1,Atm,Axl,Gbp9,Dck,Gbp2b,Tgtp1,Clcn5,Ripk2,Myo10,Cgas,Clcn7,Trib3,Kdr,Tyk2,Oas2,Atp10a,Abcc5,Mthfd1l,Irak3,Cnp,Ak4,Gtpbp2,Rab19,Arf4,Tlk2,Ciita,Ehd1,Ube2l6,Txnrd1,Prag1,Stard5,Plk3,Slfn5,Rnd1,Tspo,Plod3,Pgk1,Myo1b,Nlrc4,Pfkl,Acvrl1,Ikbke,P4ha1,Map3k6,Rnd3,Map3k8,Hk2,Nt5c3,Dnaja1,Mlkl,Pcx,Nek6,Alas1,Pnp2,Hspa1a,Map2k1,Hk3,Actb,Mecp2,Rab32,Gramd1a,Srxn1,Pde4b,Ep400,Oasl1,Phyh,Abcc1,Egln3,Ube2e2,Grk3,Apaf1,Gclc,Trib1,Gch1,Tent4a,Wars,Pim3,Rhoq,Itpkc,Gbp7,P4ha2,Cmpk2,Rab21,Layn,Mapkapk2,Prkx,Acsl5,Pdgfrb,Mov10,Siglece,Ripk3,Syk,Mcm6,Rab20,Plcl2,Ifih1,Eif2ak2,Gna15,Mark2,Kif9,Sele,Gem,Vcan,Kif3c,Rhou,Pim2,Mcm9,Mthfr,Nkiras1,Fabp7,Dhx58,Tap2,Tent2,Hck,Acsl1,Fgr,Pgs1,Hk1,Osbpl3,Dync1h1,Jak2,Gbp8,Gfpt1,Arl4a,Asns,Map2k4,Rars,Met,Rhoh,Gbp3,Mocs1,Ift22,Ptch1,Etnk1,Vrk2,S100a8,Tap1,Ass1,Kmo,Gbp2,Nod1,Helz2,Oasl2,Acvr1,Akt3,Ube2e1,Scyl2,Prkar2b,Hspa1b,Ascc3,Irak2,Clec4n,Tuba4a,Stk40,Smc5,Flt1,Rab10,Rhoc,Pdk3,Samhd1,Nlrp3,Map4k4,Pim1,Gmppb,Ddx58,Sphk1,Parp14,Tor3a,Gys1,Slfn9,Ube2f,Papss2,Pde5a,Rab9,Rhof,Hmgcs1,Fabp3,Nos2 |
| 1.449e-08 | -18.05 | cellular component organization | biological process | GO:0016043 | 4997 | 428 | 20694 | 1406 |
Mcm9,Phgdh,Lox,Ttc39c,Cnn2,Nfkb2,G3bp2,Cep350,Nrp2,Lhx2,Plek,Keap1,Cdk5r1,Prkce,Tet2,Pmaip1,Pim3,Diaph2,Acp2,Lrrc8c,Hsd17b12,Btg2,Mlkl,Spaca6,Arhgap26,P2ry12,Sik3,Spata13,Denr,Pikfyve,Sdc4,Abcc1,Katna1,Etv5,Fnbp1l,Nck1,Gpr35,Mtfr2,Srgn,Daam1,Clic4,Brd2,Tmem67,Stxbp3,Ccdc88b,Agrn,Bnip3,Psmb10,Kcna3,Ube2e1,Gpc1,Marcks,Snx10,Map2k1,Dock10,Eif4g2,Nr3c1,Cox17,Sass6,Treml4,Bcl2l11,Rictor,Tnfaip3,Hmgn3,Dek,Rap1gap2,Jak2,Akt3,Rgs14,Pdss1,Nlrp3,Ascc3,Aebp2,Pnpt1,Pdpn,Arid4a,Tnc,Kif5c,D1Ertd622e,Birc3,Sco1,Evl,Stard5,Slamf8,Ccl2,Igsf9,Col18a1,Nupr1,S1pr2,Ifrd1,Antxr1,Tor1aip1,Hspa2,Dgkh,Rhoq,Stx6,Sipa1l1,Ptk2,Rab3ip,Rac3,Kdm5b,Etv6,Pdgfrb,Fzd5,Syne2,Ddx4,Cyfip1,Marf1,Rapgef2,Plscr1,Klf7,Cav1,Spire1,Myadm,Sqstm1,Dbnl,Tagln,Itpr1,Samd9l,F11r,Kctd12,Slc2a1,Sirt1,Mmp9,Jun,Tcf4,Pcgf5,Daxx,Tuba4a,Plk3,Tnf,Tpx2,Stxbp1,Acpp,Rasgrp1,Tmem123,Ccl12,Pstpip2,Angpt1,Ikzf1,Kif9,Kat2b,Jmjd6,Uchl1,Slc16a1,Icam1,Pfkl,Rbl1,Psd,Nlgn2,Dync1h1,Dr1,Parp3,Gclc,Lpcat2,Max,Rpgrip1l,Col27a1,Lipg,Fscn1,P4ha1,Znfx1,Tifa,Lrp4,Mul1,Tmod3,Traf2,Mthfr,Rilpl1,Tgfbi,Jarid2,Micall2,Ccne1,Hap1,Rrs1,Smg7,Casp4,Top3a,Sbds,Mx1,Marco,Trip10,Scarf1,Chmp4b,Sgcb,Tomm70a,Mdn1,Zc3h12a,Fchsd2,Lnpk,Cenpe,Hspa1a,Asf1a,Rab21,Cnp,Cx3cr1,Intu,Fmnl2,Frmd6,Rubcnl,Fas,Nsd3,Pkp4,Trip13,Stau1,Sema4c,Edn1,Mmp14,Rhoc,Itga4,Dtx3l,Gclm,Irf4,Ep400,Atp11b,Cflar,Sap30,Vasp,Kdm4a,Il6,Itga5,Sema4a,Ddhd1,Gem,Samhd1,Cd34,Cacnb3,Prdm9,Thbs1,Plk2,Fbxo4,Chd9,Prnp,Nr4a3,Psmd10,Hk2,Rhof,Gja1,Dnaaf3,Itgav,Rtp4,Casp3,Pttg1,Hmga2,Mdm2,Palld,Pdgfc,Cx3cl1,Atp6v1d,Col11a2,Gfpt1,Plaat3,Setdb2,Egr2,Kdr,Fcgr2b,Gch1,Ift57,Me1,H3f3b,Met,Irgm1,Rab10,Kmt5a,Ext1,Plod2,Mark2,Rnd1,Kdm6b,Mmp25,Bcl6,Plod3,Pdlim7,Ppp1r15a,Tor1aip2,Lpar1,Ikbke,Pdgfb,Dst,Ero1l,Lst1,Lcn2,Kcnj2,Sec24a,Hcls1,Tapbp,Sema3c,Stat3,Src,Ggct,Cycs,Ripk3,Adar,Mpp7,Crkl,Hat1,Nlrc4,Spint2,Bcor,Flrt3,Mcm6,Dnase1l3,Abcc4,Optn,Apba1,Swap70,Hopx,Rhou,Ap3b1,Phactr4,Mecp2,Cenpj,Ezr,Ddit4,Sdc2,Pf4,Apaf1,Fcgr1,Slc9a1,Spry2,Klf2,Birc2,Ntng2,Triobp,Vps54,Myc,Rsbn1,Plagl2,Abr,Cox18,Nes,Atm,Adgrl2,Tpm4,Cdyl,Ltbp2,Coa5,Whamm,Atp11a,Lyn,Parp11,Ahr,Rab32,Ptch1,Axl,Gpsm2,Txnrd1,Cnn3,Hhex,Arf4,Csrp1,Ier3,Trim36,Sod2,Fcho2,Snx2,Bcorl1,Brwd3,Pml,Ciapin1,Zyx,Pim2,Ago3,Eya4,Noct,Col4a2,Rab20,Ccl5,Igf1r,Psip1,Cutc,Nox1,Phip,Fignl2,Msr1,C3,Cd74,Ift22,Sec24b,Gsdmd,Actb,Malt1,Irgm2,Smc5,Atp10a,Scn1b,Mcmbp,Stx11,Tapbpl,Tlk2,Map4k4,Myo1b,Csf3,Mitd1,Cdc42ep2,Mx2,Hmox1,Tlr2,Rnd3,Vcpip1,Flnb,Znrf1,Pid1,Notch1,Rhoh,Ehd1,Adora2a,Mcoln2,Abcb1a,Mmp13,Xkr8,Hdac1,Cdc42ep4,Adgrg6,Nod2,Pla2g7,Flrt2,Carmil1,Tmsb10,Tap2,Lrp8,Homer1,Xrn1,Trim21,Tsku,Nectin2,Clic5,Slc12a9 |
| 1.458e-08 | -18.04 | cytokine secretion | biological process | GO:0050663 | 50 | 17 | 20694 | 1406 |
Notch2,Lyn,Nod2,Nos2,Aim2,Tlr2,Mcoln2,Lcp2,Tlr6,Itgav,Nlrc4,Rnf19b,Notch1,Nlrp3,Isg15,Optn,Trem1 |
| 1.459e-08 | -18.04 | GO_DEFENSE_RESPONSE_TO_BACTERIUM | MSigDB lists | GO_DEFENSE_RESPONSE_TO_BACTERIUM | 177 | 38 | 15632 | 1249 |
Trem1,Il12b,Clec4d,Tlr2,Hp,Tlr9,Tlr3,Ripk2,Slpi,Tlr1,Il10,Irf8,Serpine1,Nos2,S100a8,Tnfrsf14,Nod1,Myd88,Clec4e,Isg15,Fgr,H2-Q7,Tlr6,Optn,Nod2,Ifnb1,Gbp9,Gbp4,Il6,Tnfsf8,Nlrc4,H2-Q6,Ankrd17,Tnf,Spn,H2-Q4,Plac8,Syk |
| 1.459e-08 | -18.04 | GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_DN | 177 | 38 | 15632 | 1249 |
Rab20,Gpd2,Mefv,Azi2,Filip1l,Parp3,Mtmr14,Il1b,Acp2,Serpinb2,Dek,Znrf1,Il1rn,Osbpl3,Il10,Klf2,Rap1gap2,Stx11,Uba7,Nfkbid,Bst1,Csf1,Gbp3,Zfp281,Ccnd2,Rnf139,Usp25,Cdkn2d,Magohb,Lipg,Batf,Psmb9,Gpr18,Dock10,Slc39a4,Dusp2,Ccdc86,Gpr84 |
| 1.508e-08 | -18.01 | ZHENG_IL22_SIGNALING_UP | MSigDB lists | ZHENG_IL22_SIGNALING_UP | 54 | 19 | 15632 | 1249 |
Rtn1,C3,Hp,Arrdc4,Cd14,Plat,Pfkfb3,Olr1,Pf4,Apaf1,Cd38,Ccl5,S100a8,Timp1,Tifa,Slpi,Fzd1,Cxcl2,Inhba |
| 1.508e-08 | -18.01 | GO_POSITIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | 54 | 19 | 15632 | 1249 |
Tlr1,Nod2,Rasgrp1,Spn,Ccl12,Cd86,Nod1,Jak2,Cd14,Tnfrsf8,Thbs1,Pf4,Tlr9,Tlr3,Mapkapk2,Ripk2,Ptafr,Tlr2,Il12b |
| 1.511e-08 | -18.01 | microglial cell activation | biological process | GO:0001774 | 29 | 13 | 20694 | 1406 |
Nampt,Casp1,Fpr2,Cx3cr1,Tlr1,Tlr9,Jun,Tlr2,Tnf,Cx3cl1,Tlr3,Jak2,Tlr6 |
| 1.511e-08 | -18.01 | leukocyte activation involved in inflammatory response | biological process | GO:0002269 | 29 | 13 | 20694 | 1406 |
Jak2,Tlr6,Tlr3,Tnf,Cx3cl1,Tlr2,Jun,Tlr9,Tlr1,Fpr2,Cx3cr1,Nampt,Casp1 |
| 1.514e-08 | -18.01 | cellular macromolecule metabolic process | biological process | GO:0044260 | 4068 | 359 | 20694 | 1406 |
Aff1,Dusp16,Birc2,Ifih1,Ppp4r2,Rnf19b,Dcp1a,Myc,Ell2,Hopx,Trim12a,Znrf3,Dcun1d3,Mecp2,Usp31,Scyl2,St3gal1,Ezr,Parp14,Tlr9,Parp8,Ripk3,Mcm10,Il12rb1,Trib1,Bcor,Usp35,Stat1,Hat1,Ranbp2,Mcm6,Swap70,Dnase1l3,Fam111a,Ikbke,Pdgfb,P4ha2,Tpst1,Stat3,Parp12,Hck,Src,Rbms1,Tnks1bp1,Egr1,Zhx2,Calcrl,Ext1,Fut8,Ube2e2,Kmt5a,Cnot4,Cgas,Kdm6b,Plod2,Mark2,Ppp1r15a,Dusp4,Plod3,Mdfic,Magohb,Phlpp2,Gfpt1,Egr2,Setdb2,Kdr,Ubash3b,Myd88,Serp1,Met,Ccnd1,Itgav,Hmga2,Ppp2r3a,Tmtc2,Dtx2,Mppe1,Mapkapk2,Pttg1,Extl2,Mdm2,Dusp8,Sap30,Hif1a,Ccnd2,Kdm4a,Ctsc,Samhd1,Ubr4,Fbxo4,Slfn8,Grk3,Prdm9,Thbs1,Plk2,Xrn1,Trim21,Tent2,Cop1,Morc3,Zfp36,Irak3,Egln3,Mmp13,Ptger4,Tgs1,Hinfp,Acvr1,S100a8,Hdac1,Tlr2,Pim1,Plpp1,Lipe,Vcpip1,Znrf1,Tiparp,Irak2,Smc5,Nos2,Irgm2,Parp9,Mcmbp,Aoah,Ptprj,Tlk2,Nmi,Gcnt2,Dyrk2,Icosl,Trmt1l,Map4k4,Ccl5,Cdkn2d,Wars,Igf1r,Larp1,Vrk2,Fgr,Map3k6,Dusp28,Junb,Malt1,Psmb6,Oas2,Rnf31,Trim36,Syk,Stat4,Pim2,Ago3,Eya4,Ccnj,Pml,Col4a2,Noct,Bfar,Parp11,Ahr,Tnip1,Chst11,Lyn,Htr2b,Lmo4,Helz2,Usp18,Axl,Trim13,Arf4,Fam20c,Ankib1,Fos,Tent4a,Atm,Dusp2,Isg20,Cdyl,Timeless,Il15,Nupr1,Dnajb2,Snapc1,Ccng2,Dusp14,Gbe1,Prag1,Fosb,Prkx,Kdm5b,Ptk2,Pdgfrb,Ptpn2,Pnpt1,Eif2ak2,Ascc3,Stat5a,Ppm1k,Map3k8,Arid4a,Apobec3,Rnf34,Herc6,Eef1e1,Psmb8,Birc3,Batf,Arrdc4,Dcp2,Gtpbp2,Psmb9,Med21,Tyk2,Rictor,Inhba,Tnfaip3,Jak2,Tcea1,Sphk1,Akt3,Rnf139,Spsb1,Psma6,Dpy19l1,Gpc1,Ube2e1,Flt1,Usp12,Lif,Map2k1,Pdk3,Eif4g2,Trim12c,Phlda1,Peli1,Nr3c1,Tmem67,Agrn,Psmb10,Bnip3,Rffl,Sik3,Dusp6,Uba7,Gys1,Rbbp8,Trim56,Casp8,Denr,Acvrl1,Rnf19a,Nck1,Keap1,Prkce,Cdk5r1,Ppm1l,Ppp2r5a,Tlr3,Isg15,Sla,Pim3,Il1b,Acp2,Tet2,Polr2g,Trib3,Btg2,St3gal5,Mlkl,Lox,Saa3,Otud1,Mcm9,Acvr1b,Pgap2,Dusp1,Bmp2,Ube2l6,Cpeb4,Ube2f,Nsd3,Hmga1,Trip13,Socs7,Ccr3,Med13,Sgk3,Mtmr14,Ep400,Irf4,Dtx3l,Naa25,Usp42,Hspa1a,Map2k4,Ppp1r15b,Asf1a,Il10,Pigv,Klhl25,Rars,Phlpp1,Usp53,Top3a,Crbn,Mocs1,Chmp4b,Il18,Zc3h12a,Rnf14,Stk40,Mul1,Ripk2,Traf2,Nek6,Usp25,Rnaset2a,Smg7,Jarid2,Ccne1,Hivep2,Tut7,B3gnt5,Hk1,Jmjd6,Kat2b,Uchl1,Dr1,Parp3,P4ha1,Tnf,Plk3,Mapkbp1,Pcgf5,Jun,Tcf4,Rnf135,Armc8,St3gal6,Parp10,Taf4b,Caml,Ccl12,Dse,Trim30a,St3gal3,Osm,Cav1,Sirt1,Arel1,Mgat1,Ksr1,Mmd,Ddx4,Nfil3,Ppp2r2a,Mrpl52,Marf1,Sde2,Dusp5 |
| 1.534e-08 | -17.99 | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | 170 | 37 | 15632 | 1249 |
Cish,Atp13a1,Gsr,Glipr2,Optn,Casp1,Abcc5,Sqstm1,Zbp1,Ahsa1,Sgk3,Ahr,Nfkbiz,Fas,Irs2,Slco3a1,Upp1,Kat2b,Cyth3,Tab2,Tlr1,St3gal5,Spen,Trim26,Tdrd7,Syne2,G3bp2,Txn1,4930523C07Rik,Birc3,Klf2,Tnfsf14,Rsbn1,Il15ra,Zc3h12a,Sema4c,Mafg |
| 1.548e-08 | -17.98 | Inflammatory bowel disease (IBD) | KEGG pathways | ko05321 | 59 | 21 | 7931 | 713 |
Il18,Nfkb1,Jun,Stat1,Tlr2,Il10,H2-Aa,Nod2,Stat4,Il12rb1,Tnf,Il1b,H2-Eb1,Il12b,Il2rg,Stat3,H2-Ab1,Il1a,Il4ra,Il18rap,Il6 |
| 1.548e-08 | -17.98 | Inflammatory bowel disease (IBD) | KEGG pathways | mmu05321 | 59 | 21 | 7931 | 713 |
Jun,Il18,Nfkb1,Stat1,Tlr2,H2-Aa,Nod2,Il10,Il12rb1,Stat4,Tnf,H2-Eb1,Il2rg,Il12b,Il1b,Il6,H2-Ab1,Stat3,Il1a,Il18rap,Il4ra |
| 1.556e-08 | -17.98 | positive regulation of NIK/NF-kappaB signaling | biological process | GO:1901224 | 75 | 21 | 20694 | 1406 |
Tlr1,Glrx,Ago3,Il1b,Tlr9,Irak2,Il18,Cd14,Malt1,Nod2,Nod1,Tnfsf15,Tlr2,Eif2ak2,Tnfsf14,Tnf,Tlr3,Sphk1,Ikbkg,Traf2,Edn1 |
| 1.572e-08 | -17.97 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 254 | 48 | 15632 | 1249 |
Edn1,Stap1,Ptpn2,Cx3cr1,Ifit1bl1,Spn,Eif2ak2,Ccl12,Chmp4b,Cd34,Plau,Tspo,Ubash3b,Nr1h3,Nlrp3,Mul1,Abr,Smpdl3b,Fabp7,Htra1,Il10,Sema3c,Rabgef1,Nfkb1,Tnfrsf1b,Trib1,Mefv,Adrb2,Sema4a,Sema4c,Socs3,Dhx58,Notch1,Tnfaip3,Calcrl,Nfkbil1,Prdm1,Pdgfb,Serpine1,Ifit1bl2,Gja1,Plaur,Thbs1,Plat,Serpinb2,Il12b,Ptger4,Zc3h12a |
| 1.598e-08 | -17.95 | GSE25677_MPL_VS_R848_STIM_BCELL_DN | MSigDB lists | GSE25677_MPL_VS_R848_STIM_BCELL_DN | 163 | 36 | 15632 | 1249 |
Akt3,Med13,Snx2,Stat4,Rictor,Dgka,Pde4b,Card6,Myadm,Irf8,Plekha2,Jak2,Plcl2,Socs7,Cd55,Cd200,Aida,Gpd2,Nr4a3,Fchsd2,Stap1,Arhgap26,B3gnt5,Gramd1a,Cnn2,Klf6,Klf3,Ifnar1,Arhgef3,Bcl6,Samhd1,Ier2,Irf2,Rhoh,Isg15,Sell |
| 1.611e-08 | -17.94 | GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN | MSigDB lists | GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN | 185 | 39 | 15632 | 1249 |
Sell,Agtrap,Itga4,Pml,Chmp4b,Slc48a1,Arhgef3,Tnf,Parp8,Cst7,Hdac1,Kdm5b,Rsad2,Tapbp,Ifnb1,Tbc1d1,Gclm,Rhoq,Pdpn,Pnp2,Irf1,Pim1,Ier3,Mthfd2,Mtdh,Pkp4,Slfn3,Acsl5,Ldlr,Slfn4,Atp6v1d,Ankib1,Snx10,Ccne1,Brwd3,Wars,Kctd12,Cnn3,Trim21 |
| 1.611e-08 | -17.94 | GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_DN | 185 | 39 | 15632 | 1249 |
Ctsc,Fcgr2b,Stat3,Ccr3,Gadd45g,Hdac1,Il18bp,Txnrd1,Ifnar1,Tiparp,Slc2a1,Timp1,Myd88,Ahr,Nupr1,Cdkn2d,Tlr6,Prdm1,Il4ra,H2-Aa,Noc4l,Zfp36,G3bp2,Asns,Ccl4,Kdr,Abcc1,Nfil3,Hmox1,Ppa1,Socs3,Kif5c,Pdzd11,Acsl1,Gpd2,Ier3,Tgfbi,Pim1,4930453N24Rik |
| 1.611e-08 | -17.94 | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_UP | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_UP | 185 | 39 | 15632 | 1249 |
Psme2,Usp12,Inhba,Slc25a12,Stat4,Spint2,Ifit1bl2,Txn1,Nfkb1,Tnfrsf1b,Ppp1r15a,Ogfr,Tnip1,Pfkl,Pgk1,Il1b,Fndc3a,Mmp9,Pim1,Ier3,Sat1,Il6,Gadd45g,Ehd1,Ifit1bl1,N4bp1,Sod2,Agrn,Dock4,Gys1,Crim1,Olr1,Gbp2,Tnfaip3,Tap1,Marcksl1,Icam1,Gbe1,Sell |
| 1.662e-08 | -17.91 | DNA-binding transcription factor activity, RNA polymerase II-specific | molecular function | GO:0000981 | 764 | 95 | 20217 | 1400 |
Stat2,Ahr,Irf1,Hivep2,Stat3,Myc,Zbtb5,Eno1,Etv3,Stat1,Pou3f1,Ifi211,Cebpd,Nfkb1,Pbx1,Fosb,Prdm1,Irf7,Sirt1,Nr4a1,Nr1h3,Max,Ier2,Mecp2,Etv6,Klf2,Plagl2,Tfec,Hmga2,Spic,Ikzf1,Gfi1,Irf8,Fubp1,Stat5a,Tcf4,Hhex,Ifi205,Etv5,Irf4,Relb,Hinfp,Egr2,Rel,Ifi203,Plscr1,Egr3,Klf7,Junb,Klf8,Nr3c1,Ets2,Phf6,Csrnp1,Nfil3,Ifi204,Ifi213,Jun,Foxp4,Notch1,Irf2,Atf3,Egr1,Zfp281,Plagl1,Ifi209,Tal2,Btg2,Klf3,Klf6,Mndal,Mafg,Jdp2,Arid5b,Jarid2,Aebp2,Bcl6,Zeb1,Mxd1,Pttg1,Fos,Nr4a3,Ifi214,Mycl,Dach1,Nfkb2,Batf,Pou2f2,Lhx2,Nfxl1,Stat4,Hif1a,Ifi208,Ifi207,Hmga1 |
| 1.677e-08 | -17.90 | positive regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070304 | 173 | 34 | 20694 | 1406 |
Mapkbp1,Mid1,Tnf,Mdfic,Eif2ak2,Il1a,Mul1,Ripk2,Traf2,Syk,Rasgrp1,Bmp2,Map2k4,Fcgr2b,Myd88,Met,Map4k4,Tlr9,Lyn,Nod2,Nod1,Nox1,Tlr6,Edn1,Sema4c,Sphk1,Tlr3,Il1b,Il1rn,Gadd45b,Zc3h12a,Fzd5,Mlkl,Gadd45g |
| 1.684e-08 | -17.90 | GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | 142 | 33 | 15632 | 1249 |
Birc2,Tnf,Ass1,Syk,Bnip3,Edn1,Stat3,Il6,Icam1,Hif1a,Ripk3,Atp2b4,Cd34,Plau,Tspo,Cav1,Pid1,Il10,Klf2,Pdgfrb,Pdk3,Gch1,Hk2,Pdgfb,Ptgs2,Hp,Ptger4,Zc3h12a,Il1b,Cdkn1a,Arf4,Jak2,Thbs1 |
| 1.701e-08 | -17.89 | SMIRNOV_RESPONSE_TO_IR_2HR_UP | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_2HR_UP | 44 | 17 | 15632 | 1249 |
Gdf15,Slc7a11,Plk2,Ppp1r15a,Jun,Rab11fip1,Mdm2,Fas,Atf3,Rnf19b,Ptger4,Pim1,Ier3,Slc30a1,Cd83,H3f3b,Cdkn1a |
| 1.710e-08 | -17.88 | REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE | MSigDB lists | REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE | 77 | 23 | 15632 | 1249 |
Tlr1,Nfkbib,Map2k1,Dusp6,Ikbkg,Irak2,Nfkb2,Ppp2r1b,Tlr2,Map2k4,Ripk2,Nod2,Dusp4,Peli1,Fos,Jun,Nfkbia,Irak3,Myd88,Nod1,Tab2,Tlr6,Mapkapk2 |
| 1.714e-08 | -17.88 | GSE30083_SP1_VS_SP3_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP3_THYMOCYTE_DN | 178 | 38 | 15632 | 1249 |
Slfn5,Daxx,Hvcn1,Rab3ip,Pde3b,Tspo,Crlf3,Traf5,Rnf135,Ifih1,Usp18,Cers6,Cd200r4,Peli1,Ifi44,Ppp2r5a,Rab21,Tbc1d1,Irgm2,Klf3,Ifit1bl1,Ms4a6d,Oas1g,Herc6,Syne2,Dgka,Oas2,Oas1a,Slc25a12,Tlr1,Alas1,Piezo1,Pstpip2,Plekha2,Irf7,Klf2,Ifit1bl2,Pde4b |
| 1.714e-08 | -17.88 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_UP | 178 | 38 | 15632 | 1249 |
G3bp2,Ampd3,H2-Aa,Map2k1,Tnfrsf1b,Plaur,Zhx2,Vrk2,Cdkn1a,Il1rn,Fscn1,Vcam1,Cflar,Rgs1,Tnfaip2,Rcan1,Acsl1,Ier3,Mthfd2,Ldha,Mmp9,Dusp5,Optn,Rbpms,Gadd45g,Sat1,Gpr35,Ets2,Nfkbia,Cst7,Tnfaip3,Icam1,Irs2,Dmxl2,Traf1,Cdk5r1,Marcksl1,Cdkn2d |
| 1.714e-08 | -17.88 | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_DN | 178 | 38 | 15632 | 1249 |
Apaf1,Irf2,Sphk1,Sertad3,Nkiras1,Bbx,Egr2,Cebpd,C1ra,Spryd7,Hspa1a,Tank,Hcls1,Dek,Cxcl1,Il1b,Abcc1,Hcar2,Trem1,Vegfc,Rnaset2b,Mmp9,Clec4d,Ier3,Clec5a,Ak4,Bcl9,Cxcl2,Spint2,Kctd12,Ube2e2,Dusp6,Tuba4a,Hsd17b12,Dach1,Clec4n,Rnaset2a,Myo1b |
| 1.752e-08 | -17.86 | GSE7852_TREG_VS_TCONV_FAT_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_FAT_UP | 193 | 40 | 15632 | 1249 |
Stx11,Zfp36,Atxn7l1,Arl5b,Phlda1,Piezo1,Isg20,Gem,Hopx,Samsn1,Jdp2,Rabgef1,Cdkn1a,Glrx,Lrrc8c,Osbpl3,Cxcl10,Il18,Zc3h12a,Ebi3,Hmgcs1,Dusp4,Nfkbie,Lztfl1,Fgl2,Swap70,Cyfip1,Sqstm1,Itgav,Dusp1,Zc3hav1,Relb,Enpp4,Dmxl2,Ppm1l,Tmtc2,Mapkapk2,Nfkbiz,Atf3,Prdm1 |
| 1.765e-08 | -17.85 | blood vessel morphogenesis | biological process | GO:0048514 | 422 | 61 | 20694 | 1406 |
Kdr,Syk,Pde3b,Cited2,Ptger4,Vegfc,Cx3cl1,Jun,Plau,Angpt1,Ccl2,Col4a2,Acvrl1,Prdm1,Nr4a1,Ccl12,Acvr1,Casp8,Wars,Nox1,Edn1,Clic4,Jmjd6,Notch2,Col18a1,Calcrl,Junb,Pdgfrb,Fzd5,Sec24b,Ccr3,Tnfaip2,Itgb8,Prkx,Ptk2,Hif1a,Flt1,Spred1,Pdgfb,Lox,Jag1,Ptgs2,Egr3,Thbs1,Nrp2,Ptprj,Ldlr,Sema4a,Cemip2,Gja1,Itgav,Hmox1,Ahr,Cav1,Il18,Sirt1,Zc3h12a,Tiparp,Hhex,Notch1,Pik3r6 |
| 1.767e-08 | -17.85 | negative regulation of protein serine/threonine kinase activity | biological process | GO:0071901 | 118 | 27 | 20694 | 1406 |
Dusp6,Dusp1,Spred1,Dusp8,Dusp5,Ptprj,Dusp2,Cdkn1a,Casp3,Dusp16,Prkar2b,Dnaja1,Uchl1,Lyn,Spry2,Cav1,Tnfaip3,Kat2b,Cdkn2d,Sirt1,Irak3,Aida,Dusp4,Il1b,Spred3,Hhex,Rgs14 |
| 1.772e-08 | -17.85 | regulation of cell shape | biological process | GO:0008360 | 149 | 31 | 20694 | 1406 |
Myo10,Ptk2,Mark2,Rnd1,Prag1,Rhoc,Rhoh,Fgr,Rhoq,Rhof,Phip,Icam1,Rnd3,Fmnl2,Ccl2,Hck,Cdc42ep4,Cdc42ep2,Lst1,Brwd3,Ezr,Sema4a,Ccl12,Il6,Cyfip1,Kdr,Bambi,Lpar1,Ccl3,Pdpn,Rhou |
| 1.786e-08 | -17.84 | negative regulation of transcription by RNA polymerase II | biological process | GO:0000122 | 879 | 104 | 20694 | 1406 |
Hdac1,Dach1,Ezr,Hinfp,Mecp2,Ets2,Aebp2,Hopx,Slfn1,Myc,Ptpn2,Zfp36,Etv6,Zeb1,Nr1h3,Spen,Klf2,Edn1,Nr3c1,Ifi203,Ccne1,Jarid2,Hcls1,Pdgfb,Ifi208,Parp9,Gbp4,Ifi211,Gfi1,Mndal,Notch1,Bcor,Klf8,Foxp4,Nck1,Zfp281,Mxd1,Prdm1,Mafk,Met,Ikzf1,Atf3,Phf6,Ifi207,Arid5a,Cited2,Tcf4,Jun,Plk3,Tnf,Ifi204,Daxx,Bcl6,Max,Ifi214,Arid5b,Ppp1r15a,Ednrb,Junb,Txn1,Kmt5a,Mtdh,Rbl1,Dnajb4,Dr1,Eno1,Zhx2,Notch2,Jdp2,Egr1,Timeless,Mier3,Rel,Zbtb5,Bmp2,Nfil3,Hif1a,Ciita,Sap30,Ahrr,Ifi213,Mdm2,Rfx5,Btg2,Klf3,Etv3,Sirt1,Trib3,Irf8,Il1b,Hhex,Hmga2,Sqstm1,Ifi205,Ptch1,Cav1,Klf7,Nfkb1,Relb,Ahr,Ifi209,Ccnd1,Psmd10,Nr4a3 |
| 1.796e-08 | -17.83 | GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 263 | 49 | 15632 | 1249 |
Lpar1,Adrb2,Jak2,Prkar2b,Ikbkg,Tlr6,Mapkapk2,Tpx2,Mul1,Pilrb2,Mark2,Angpt1,Map3k6,Flt1,Gadd45b,Eif2ak2,Syk,S1pr2,Nod2,Gadd45g,Tlr3,Crkl,Dusp5,Ripk2,Adora2b,Fpr1,Map3k8,Pilrb1,Thbs1,Irak2,Il1b,Txn1,Dusp6,Map2k1,Pdgfb,Tnfsf15,Malt1,Tab2,Cd74,Nod1,Bmp2,Daxx,Pdgfc,Ripk3,Mdfic,Src,Tnf,Traf2,Dbnl |
| 1.809e-08 | -17.83 | GO_REGULATION_OF_PROTEIN_IMPORT | MSigDB lists | GO_REGULATION_OF_PROTEIN_IMPORT | 171 | 37 | 15632 | 1249 |
Rbpms,Nfkbie,Il6,Psmd10,Nfkbia,Tnf,Mdfic,Angpt1,Prdx1,Ddx58,Nlrp3,Sphk1,Parp10,Nfkbil1,Sirt1,Csf3,G3bp2,Fzd1,Slc9a1,Nfkbib,Il10,Tnfsf14,Txn1,Keap1,Il1b,Cdkn1a,Jak2,Bambi,Hcls1,Ptgs2,Il12b,Tlr2,Il18,Tlr9,Tlr3,Zc3h12a,Dyrk2 |
| 1.829e-08 | -17.82 | GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | 60 | 20 | 15632 | 1249 |
Rsad2,Ifnb1,Bcl6,Fzd5,Traf2,Il10,H2-Q6,H2-Q4,Tnf,Angpt1,Irak3,Tnfrsf14,Nlrp3,Nr4a3,Cd74,Hmox1,Tlr3,Tnfsf4,H2-Q7,Malt1 |
| 1.885e-08 | -17.79 | GSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_DN | 186 | 39 | 15632 | 1249 |
Clic4,Cd300lf,Fam20c,Gca,Siglece,Tfec,Il13ra1,Ptafr,Rab20,Tgfbi,Grina,Alas1,Pstpip2,Nrp2,Rhou,AA467197,Kctd12,Wars,Slc31a2,Cd86,Cd14,Gnb4,Plau,Pilra,Hck,Dmxl2,Nr1h3,Fpr2,Igsf6,Kcnj2,Sat1,Vcan,Src,Aoah,Slc25a37,Tcf4,Dock4,Dse,Swap70 |
| 1.885e-08 | -17.79 | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_DN | MSigDB lists | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_DN | 186 | 39 | 15632 | 1249 |
Gnb4,Rhoc,Chmp4b,Marcksl1,P2ry14,Ccl22,Coa5,Gsr,B3gnt5,Ccng2,Sdc2,Glipr2,Insl6,Swap70,Idi1,Cldnd1,Gca,Fscn1,Pmepa1,Dnajb2,Epsti1,Ell2,Socs3,Cd200,Hmgcs1,Serpinb9,Rcsd1,Tapbpl,Trib1,Ep400,Htra1,Rab10,Inpp5b,Kctd12,Spint2,Map4k4,Csrp1,Txn1,Lad1 |
| 1.892e-08 | -17.78 | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP | 164 | 36 | 15632 | 1249 |
Arid5b,Kcna3,Odc1,Cd200,Pim2,Sp110,Adam19,Sipa1l1,Plekha2,Map4k4,4930523C07Rik,Birc3,Cd69,Rasgrp1,Snx2,Pikfyve,Cdk5r1,Il4ra,Kmo,Rhoh,Cd83,Traf5,Rras2,Tcf4,Swap70,Gpr18,Sp140,Plekhf2,Ehd1,Ezr,Ift57,Stap1,Fchsd2,Peli1,Myc,Fut8 |
| 1.907e-08 | -17.78 | GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 1633 | 191 | 15632 | 1249 |
Ptch1,Irf8,Htra1,Ifi203,Met,Sirt1,Jag1,Stat1,Adrb2,Tnip1,Dr1,Gfi1,Agrn,Nlrc5,Ezr,Fos,Psmd10,Edn1,Irf4,Nod2,Egr1,Atf3,Nlrp3,Plagl1,Ciita,Atp2b4,Nampt,Jarid2,Arid4a,Klf2,Pdgfb,Csf3,Zc3h12a,Cxcl10,Ptafr,Nfxl1,Pf4,Tcea1,Zhx2,Hsph1,Rbbp8,Cd40,Egr2,Cebpd,Ccnd1,Mdm2,Lif,Irf2,Hif1a,Il1a,Ddx58,Stat2,Tal2,Crlf3,Relb,Notch1,Ednrb,Rnf14,Lmo4,Pid1,Rel,Cav1,Zfp36,Ifi211,Spen,Zeb1,Egln3,Pou2f2,Zscan29,Tlr9,Mtdh,Ifi204,Lhx2,Psip1,Hmga1,Cited2,Spic,Bcor,Nr1h3,Kat2b,Rbl1,Ahr,Klf7,Foxp4,Brwd3,Med21,Osm,Irf7,Serpine1,Hopx,Fzd5,Sap30,Ripk2,Pcgf5,Hmox1,Nr4a3,Il1b,Stat5a,Ifi209,Tcf4,Batf2,Tnfsf8,Stat3,Mecp2,Aebp2,Csrnp1,Plk3,Prdm1,Zfp281,Pbx1,Batf,Plagl2,Dach1,Il10,Timeless,Plscr1,Bcl9,Tlr2,Mafg,Acvr1b,Irf1,Hcls1,Nfkbia,Jun,Tet2,Myc,Il6,Ikzf1,Lrp8,Nfkbiz,Etv3,Phip,Hinfp,Txn1,Junb,Ifi208,Btg2,Maff,Nfkbid,Kdm6b,Dek,Lrp4,Ifi213,Ifi205,Eno1,Rhoq,Nr3c1,Acvrl1,Acvr1,Mxd1,Hhex,Bmp2,Daxx,Ahrr,Jdp2,Nfkb1,Ikbkg,Mndal,Med13,Slc9a1,Etv6,Max,Arf4,Nfil3,Sqstm1,Sod2,Nr4a1,Plac8,Ets2,Ifnb1,Nck1,Ifi214,Ifi207,Brd2,Fosb,Ppp1r15a,Fzd1,Inhba,Tlr3,Arid5b,Trib3,Nfkb2,Tnf,Klf6,Bcl6,Arid5a,Mafk,Hdac1,Nupr1,Ncoa7,Etv5 |
| 1.959e-08 | -17.75 | GSE13547_WT_VS_ZFX_KO_BCELL_DN | MSigDB lists | GSE13547_WT_VS_ZFX_KO_BCELL_DN | 157 | 35 | 15632 | 1249 |
Rbbp8,Casp1,Insl6,Nr4a1,Phf11b,Gadd45b,Plac8,Psma6,Cox17,Chst11,Carhsp1,Irf4,Prdm1,Phf11c,Slamf7,Phf11a,Batf,Gem,Fosb,Myadm,Snx10,Hat1,Smpdl3b,Trip13,Phlda1,Cxcl10,Serpinb9,Phf11d,Ldha,Glrx,Nfil3,Pgk1,Rgs1,Clic4,Osbpl3 |
| 1.959e-08 | -17.75 | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_DN | 157 | 35 | 15632 | 1249 |
Rap2c,Clcf1,Cflar,Arf4,Ak4,Dnaja2,Fndc3a,Egr3,Prdm9,Met,Stat4,Rnf19a,Wars,Ppp4r2,Arl5b,Nrp2,Osm,Lad1,Map4k4,Birc3,Myo10,Tnfaip3,Rab3ip,Il15,Tab2,Ube2e1,Tnfsf8,Rab11fip1,Peli1,Jun,Birc2,Cd40,Homer1,Plekhf2,Slc25a37 |
| 1.964e-08 | -17.75 | GO_SIDE_OF_MEMBRANE | MSigDB lists | GO_SIDE_OF_MEMBRANE | 380 | 63 | 15632 | 1249 |
Lyn,Ptk2,Itga5,Jak2,Rgs1,Tmem123,Ldlr,Gna15,Gem,Rnf31,Cd69,Sdc1,Cyth3,Fas,Chmp4b,Tnfrsf14,Cd34,F10,Gng11,Cd80,Dnaja1,Ezr,H2-Q4,Spn,Syk,Itgav,Pdpn,Il6,Cxcl10,Il2rg,H2-Ab1,Gng4,Gng12,Pkp4,Vcam1,Thbs1,Cd274,Cd86,Ccr1,H2-Eb1,Il12rb1,Tyk2,H2-Aa,Icam1,Cd74,Fgr,Sell,H2-Q7,Hck,Cd83,Traf5,Cd14,P2ry12,H2-Q6,Traf2,Birc2,Cd40,Src,Tnf,Errfi1,Gsr,Tapbp,Rab21 |
| 1.969e-08 | -17.74 | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | 96 | 26 | 15632 | 1249 |
P4ha1,Nampt,Cav1,Zfp36,Isg20,Dusp5,Pim2,Slc31a1,Ldha,Ldlr,Cflar,Gfpt1,Nfil3,Pgk1,Apobec3,Nr4a1,Pnp2,Myc,Cycs,Casp3,Atf3,Itga4,Prdm1,Slamf7,Tnfaip3,Cd38 |
| 1.969e-08 | -17.74 | negative regulation of tumor necrosis factor superfamily cytokine production | biological process | GO:1903556 | 63 | 19 | 20694 | 1406 |
Irak3,Nfkbil1,Cd34,Zc3h12a,Acp5,Sirt1,Il10,Axl,Cd274,Ptger4,Tlr6,Arg2,Errfi1,Tnfaip3,Tspo,Nod2,Trim30a,Cx3cl1,Gpr18 |
| 1.972e-08 | -17.74 | Osteoclast differentiation | KEGG pathways | mmu04380 | 129 | 33 | 7931 | 713 |
Traf2,Fosb,Pik3cd,Nfkbia,Ifnar1,Syk,Tnf,Stat1,Nfkb1,Tyk2,Jun,Acp5,Akt3,Fcgr4,Csf1,Fcgr1,Socs3,Map2k1,Nox1,Ikbkg,Il1a,Nfkb2,Stat2,Junb,Il1b,Fcgr2b,Tab2,Lcp2,Socs1,Ifnb1,Sqstm1,Fos,Relb |
| 1.972e-08 | -17.74 | Osteoclast differentiation | KEGG pathways | ko04380 | 129 | 33 | 7931 | 713 |
Csf1,Fcgr4,Map2k1,Socs3,Fcgr1,Stat2,Nfkb2,Il1a,Ikbkg,Nox1,Lcp2,Tab2,Fcgr2b,Il1b,Junb,Ifnb1,Socs1,Sqstm1,Fos,Relb,Traf2,Pik3cd,Fosb,Nfkbia,Tnf,Syk,Ifnar1,Stat1,Jun,Tyk2,Nfkb1,Acp5,Akt3 |
| 1.973e-08 | -17.74 | GO_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION | 26 | 13 | 15632 | 1249 |
Cd86,Bcl6,Il12rb1,Irf4,Il6,Nlrp3,Il4ra,Il12b,Tnfsf4,Hlx,Ripk2,Il27,Cd80 |
| 1.991e-08 | -17.73 | negative regulation of establishment of protein localization | biological process | GO:1904950 | 208 | 38 | 20694 | 1406 |
Nlrp3,Nr1h3,Pim3,Txn1,Il1b,Lgals9,Zc3h12a,Rgcc,Frmd4a,Cd200,Rabgef1,Srgn,Tnfaip3,Klf7,Tlr6,Pfkl,Dnaja1,Tnfsf4,Ezr,Il10,Pml,Angpt1,Cd34,Map4k4,Hsph1,Hdac1,Mdfic,Mapkbp1,Tnf,Rhbdf2,Cx3cl1,Gbp4,Rsad2,Rab11fip1,Arg2,Ptger4,Pde3b,Il6 |
| 2.004e-08 | -17.73 | GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN | 150 | 34 | 15632 | 1249 |
Mthfr,Ddx60,Atf3,P2ry14,Stat2,Zbp1,Gclc,Slfn5,Hk3,Ifit2,Zyx,Oas3,Znfx1,Ifi44,Kcnj2,Tapbp,Dock10,Samd9l,Cpeb4,Atp10a,Cxcl10,Ifit3b,Parp11,Trib3,Clic4,Rgs1,Trafd1,Keap1,Psmb8,Irf7,Mov10,Ifit3,Parp12,Xaf1 |
| 2.012e-08 | -17.72 | GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_DN | MSigDB lists | GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_DN | 179 | 38 | 15632 | 1249 |
Pim2,Map2k4,Irf1,Ifi204,Cxcl1,Jak2,Atm,Gem,Mndal,Rel,Plscr1,Psme2,Ifi208,Ube2l6,Ifi211,Ifi203,Slc25a12,Rhoh,Atf3,Traf1,Arg2,Ifi214,Isg15,Pttg1,Mdfic,Gbp2,Ifi207,Apobec3,Ifi213,Ifi205,Rbbp8,Bcl6,Ifi209,B4galt4,Il6,Ifi44,Sat1,Nfkbie |
| 2.015e-08 | -17.72 | negative regulation of immune effector process | biological process | GO:0002698 | 134 | 29 | 20694 | 1406 |
Tap2,Hmox1,Rabgef1,Serpinb9,Il4ra,Nod2,Ifnb1,Tnfaip3,Fgl2,Zc3h12a,Bcl6,Irak3,Tap1,Clec2d,Dhx58,Lgals9,Parp3,Htra1,Tnf,Abr,Hlx,Mul1,Angpt1,Irf1,Spn,Slamf8,Tnfsf4,Fcgr2b,Il10 |
| 2.025e-08 | -17.72 | nucleoside phosphate binding | molecular function | GO:1901265 | 2021 | 203 | 20217 | 1400 |
Gna15,Mark2,Kif9,Gem,Kif3c,Rhou,Pim2,Mapkapk2,Prkx,Acsl5,Mov10,Pdgfrb,Ripk3,Syk,Mcm6,Rab20,Ifih1,Eif2ak2,Fgr,Pgs1,Hk1,Dync1h1,Jak2,Arl4a,Gbp8,Asns,Rars,Map2k4,Met,Mcm9,Mthfr,Nkiras1,Dhx58,Tap2,Tent2,Hck,Acsl1,Pde4b,Ep400,Oasl1,Abcc1,Ube2e2,Actb,Mecp2,Rab32,Srxn1,Rhoq,Itpkc,Gbp7,Cmpk2,Rab21,Grk3,Apaf1,Gclc,Trib1,Gch1,Tent4a,Wars,Pim3,Rhoc,Rab10,Pdk3,Samhd1,Map4k4,Nlrp3,Pim1,Gmppb,Sphk1,Ddx58,Tuba4a,Stk40,Smc5,Flt1,Slfn9,Ube2f,Papss2,Pde5a,Rab9,Rhof,Nos2,Parp14,Tor3a,Vrk2,Tap1,Ass1,Kmo,Gbp2,Nod1,Helz2,Rhoh,Gbp3,Ift22,Mocs1,Etnk1,Ascc3,Irak2,Oasl2,Acvr1,Akt3,Ube2e1,Scyl2,Prkar2b,Hspa1b,Acvr1b,Mx1,Iigp1,Rras2,Rap2c,Irgq,Sgk3,Slfn8,Fam20c,P2ry2,Igf1r,Gk,Arl5c,Hspa2,Src,Axl,Gbp9,Dck,Gbp2b,Tgtp1,Swap70,Pik3cd,Hsph1,Atm,Gpsm2,Plk2,Sik3,Dnaja2,Gsr,Atp13a1,Dgka,Katna1,Sirt1,Nlrc5,Trip13,Chd9,Ddx4,Abcb1a,Nod2,Atp11a,Prkce,Lyn,Arl5b,Me1,Phgdh,Hcar2,Ksr1,Oas3,Cenpe,Pikfyve,Rac3,Dyrk2,Irgm1,Ptk2,Atp2b4,Pfkl,Acvrl1,Ikbke,Map3k6,Prag1,Plk3,Slfn5,Rnd1,Pgk1,Nlrc4,Myo1b,Hspa1a,Map2k1,Hk3,Rnd3,Map3k8,Hk2,Nt5c3,Dnaja1,Mlkl,Pcx,Nek6,Trib3,Kdr,Tyk2,Oas2,Atp10a,Clcn5,Ripk2,Myo10,Cgas,Clcn7,Ciita,Ehd1,Ube2l6,Txnrd1,Abcc5,Mthfd1l,Irak3,Cnp,Ak4,Gtpbp2,Rab19,Arf4,Tlk2 |
| 2.025e-08 | -17.72 | nucleotide binding | molecular function | GO:0000166 | 2021 | 203 | 20217 | 1400 |
Etnk1,Rhoh,Gbp3,Ift22,Mocs1,Nod1,Helz2,Gbp2,Tap1,Ass1,Kmo,Vrk2,Prkar2b,Hspa1b,Akt3,Ube2e1,Scyl2,Oasl2,Acvr1,Irak2,Ascc3,Flt1,Stk40,Tuba4a,Smc5,Pim1,Gmppb,Sphk1,Ddx58,Samhd1,Nlrp3,Map4k4,Rhoc,Rab10,Pdk3,Parp14,Tor3a,Nos2,Rab9,Rhof,Pde5a,Slfn9,Ube2f,Papss2,Rab32,Srxn1,Mecp2,Actb,Abcc1,Ube2e2,Oasl1,Pde4b,Ep400,Tent4a,Gch1,Wars,Pim3,Apaf1,Trib1,Gclc,Grk3,Rab21,Gbp7,Cmpk2,Itpkc,Rhoq,Ifih1,Eif2ak2,Rab20,Mcm6,Ripk3,Syk,Mapkapk2,Prkx,Pdgfrb,Mov10,Acsl5,Pim2,Rhou,Kif3c,Gem,Gna15,Mark2,Kif9,Tent2,Hck,Acsl1,Tap2,Nkiras1,Dhx58,Mcm9,Mthfr,Rars,Map2k4,Met,Jak2,Gbp8,Arl4a,Asns,Dync1h1,Pgs1,Fgr,Hk1,Clcn7,Myo10,Cgas,Ripk2,Clcn5,Tyk2,Atp10a,Oas2,Kdr,Trib3,Arf4,Tlk2,Gtpbp2,Rab19,Irak3,Cnp,Ak4,Abcc5,Mthfd1l,Ehd1,Ube2l6,Txnrd1,Ciita,Pgk1,Myo1b,Nlrc4,Slfn5,Rnd1,Plk3,Prag1,Map3k6,Ikbke,Pfkl,Acvrl1,Pcx,Nek6,Dnaja1,Mlkl,Nt5c3,Rnd3,Map3k8,Hk2,Map2k1,Hk3,Hspa1a,Phgdh,Me1,Atp11a,Lyn,Prkce,Arl5b,Trip13,Chd9,Abcb1a,Ddx4,Nod2,Dgka,Katna1,Sirt1,Nlrc5,Gpsm2,Plk2,Gsr,Sik3,Dnaja2,Atp13a1,Atp2b4,Irgm1,Rac3,Dyrk2,Ptk2,Pikfyve,Cenpe,Hcar2,Ksr1,Oas3,Hspa2,Src,Gk,Arl5c,Igf1r,P2ry2,Slfn8,Fam20c,Sgk3,Rap2c,Irgq,Mx1,Iigp1,Rras2,Acvr1b,Atm,Pik3cd,Hsph1,Swap70,Tgtp1,Gbp2b,Gbp9,Dck,Axl |
| 2.041e-08 | -17.71 | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 194 | 40 | 15632 | 1249 |
Relb,Cd38,Sla,Sav1,Hif1a,Spata13,Cyth3,Mxd1,Ccng2,Bcl2a1d,Rin2,Pnp2,Tpst1,Homer1,Cyfip1,Ifnar1,Rapgef5,Bcl2a1b,Gadd45b,Stat5a,Glrx,Ralgds,Chd9,Tnip1,Bcl2a1a,Nfxl1,Il18,Pim1,Cd200,Kif5c,Ptprj,Egln3,Mmd,Gem,Gbp7,Il10,Cd274,Hopx,Slc4a7,Nampt |
| 2.041e-08 | -17.71 | GSE23568_ID3_KO_VS_WT_CD8_TCELL_DN | MSigDB lists | GSE23568_ID3_KO_VS_WT_CD8_TCELL_DN | 194 | 40 | 15632 | 1249 |
C1ra,Fcgr2b,Irf4,Ctsc,Prkce,Carhsp1,Il4i1,Rhoq,Tcf4,Tpst1,Cd40,Plac8,Syk,Clcn5,Hck,Ciita,Cd83,Hhex,Mcoln2,Pml,Snx2,Pla2g7,Kctd12,Cnn3,H2-Aa,Irf8,Zc3h12c,Jarid2,Slc4a7,Tor3a,Myadm,Clic4,Nr4a3,Adrb2,Map3k8,Gpd2,Lyn,Tmod3,Ell2,Slc31a1 |
| 2.049e-08 | -17.70 | GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 764 | 105 | 15632 | 1249 |
Junb,Cd86,Pik3r6,Scn1b,Csf3,Hap1,Ptger4,Zc3h12a,Ptgs2,Il12b,Cmklr1,Bambi,Vegfc,Pf4,Ehd1,Axl,Rgs14,Pnp2,Acvr1,Acvrl1,Hlx,Lif,Pml,Hif1a,Sphk1,Isg15,Cd83,Bmp2,Notch1,Ccne1,Tnfsf14,P2ry2,Ptch1,Jag1,Rasgrp1,Tnfsf4,Socs3,Acvr1b,Clcf1,Kdr,Hcls1,Fam20c,Cx3cr1,Fos,Msr1,Jun,Edn1,Il6,Triobp,Lrp8,Nlrp3,Il4ra,Htr2a,Mark2,Ccr1,Ccl5,Gja1,Gdf15,Myadm,Hopx,Map2k1,Pdlim7,Rapgef2,Inhba,Il12rb1,Ripk2,Gcnt2,Kitl,Il1b,Tnf,Tcf4,Bcl6,Rab21,Glipr2,Gpr68,Prdm1,Cd74,Sav1,Etv5,Nfkb1,Casp8,Zeb1,Csf1,Spen,Mmd,Egr3,Rac3,Lpar1,Trib1,Lyn,Jak2,Syk,Mmp14,S1pr2,Ap3b1,Pde5a,Scarf1,Kat2b,Mul1,Cx3cl1,Cd34,Il15,Gpc1,Cd80,Tspo |
| 2.102e-08 | -17.68 | Interferon Signaling | REACTOME pathways | R-MMU-913531 | 61 | 21 | 8608 | 757 |
Socs1,Ifna2,Stat1,Ifna4,Ifna6,Ifna1,Flnb,Ifnb1,Jak2,Ifnar1,Stat2,Isg15,Socs3,Eif4g2,Ube2l6,Ptpn2,Ifna5,Tyk2,Uba7,Usp18,Ube2e1 |
| 2.120e-08 | -17.67 | SINGH_NFE2L2_TARGETS | MSigDB lists | SINGH_NFE2L2_TARGETS | 15 | 10 | 15632 | 1249 |
Txnrd1,Hmox1,Txn1,Me1,Gsr,Nqo1,Abcc1,Gclc,Gclm,Prdx1 |
| 2.150e-08 | -17.66 | positive regulation of apoptotic signaling pathway | biological process | GO:2001235 | 183 | 35 | 20694 | 1406 |
Adora2a,Daxx,Fam162a,Traf2,Ppp2r1b,Eef1e1,Ctsc,Plaur,S100a8,Atf3,Casp2,Pml,Casp8,Bcl2l11,Tnfsf10,Plscr1,Thbs1,Nck1,Apaf1,Nupr1,Ripk3,Fas,Inhba,Cav1,Osm,Ifnb1,Nox1,Jak2,Pmaip1,Plagl2,Ptpn2,Mmp9,Sirt1,Bnip3,Myc |
| 2.201e-08 | -17.63 | GSE23321_CENTRAL_MEMORY_VS_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE23321_CENTRAL_MEMORY_VS_NAIVE_CD8_TCELL_UP | 187 | 39 | 15632 | 1249 |
Cxcl2,Inhba,Med13,Ampd3,Phlda1,Csf1,Osm,Sipa1l1,Irf7,Lcn2,Marco,Vezt,S100a8,5430427O19Rik,Fam162a,Serpinb2,Fam20c,Fpr1,Dnajb4,Ptgs2,Mmp9,Slc39a4,Tiparp,Acpp,Fos,Mtus1,Agrn,Nr4a1,Adhfe1,Plac8,Cd38,Jmjd6,Sell,Pigv,Il1a,Upp1,Egr1,Plk3,Nfkbiz |
| 2.201e-08 | -17.63 | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP | 187 | 39 | 15632 | 1249 |
P4ha1,Slc31a2,Tor3a,Atp6v1d,Irf8,Csf1,Bst1,Mmp9,Nr4a3,Lpar1,Tgfbi,Slamf8,Ms4a6d,Cdkn1a,Nfil3,Prkar2b,Agpat4,Fam162a,Txnrd1,Flt1,Igsf6,Slc15a3,Fcgr2b,Ggct,Spry2,Ctsc,Cpd,Chst11,Nfkbie,Sdc2,Stxbp1,Fgr,Slc30a1,Kmo,Slc48a1,Cd83,Sdc4,Pdgfc,Hk3 |
| 2.235e-08 | -17.62 | PID_HIV_NEF_PATHWAY | MSigDB lists | PID_HIV_NEF_PATHWAY | 35 | 15 | 15632 | 1249 |
Nfkb1,Nfkbia,Birc3,Tnf,Casp8,Traf2,Cycs,Casp3,Casp2,Casp7,Fas,Traf1,Cflar,Daxx,Apaf1 |
| 2.244e-08 | -17.61 | neuroinflammatory response | biological process | GO:0150076 | 40 | 15 | 20694 | 1406 |
Tlr3,Tlr6,Jak2,Jun,Adora2a,Tlr2,Tnf,Cx3cl1,Tlr9,Nampt,Casp1,Fpr2,Cx3cr1,Tlr1,Il1b |
| 2.326e-08 | -17.58 | negative regulation of nucleic acid-templated transcription | biological process | GO:1903507 | 1204 | 132 | 20694 | 1406 |
Parp9,Ifi208,Znfx1,Gbp4,Pdgfb,Ifi203,Ccne1,Jarid2,Hcls1,Nfkbie,Nr3c1,Src,Hat1,Cdyl2,Prdx5,Bcor,Foxp4,Klf8,Gfi1,Mndal,Notch1,Ifi211,Aebp2,Hopx,Slfn1,Mecp2,Ets2,Hspa1a,Arid4a,Cenpj,Dach1,Ezr,Hinfp,Tnfsf4,Hdac1,Irf1,Nsd3,Spen,Klf2,Edn1,Kdm5b,Zeb1,Etv6,Tle3,Nr1h3,Myc,Ptpn2,Cebpd,Zfp36,Ciita,Sap30,Ifi213,Ahrr,Nfil3,Kdm4a,Hif1a,Rel,Zbtb5,Bmp2,Cd38,Timeless,Mier3,Nmral1,Dusp5,Cdyl,Cav1,Klf7,Zmynd15,Nfkb1,Relb,Ahr,Ifi209,Ccnd1,Psmd10,Cdk5r1,Nr4a3,Ifi205,Sqstm1,Ptch1,Riox2,Trib3,Irf8,Il1b,Hhex,Hmga2,Rfx5,Mdm2,Btg2,Etv3,Klf3,Sirt1,Jun,Tcf4,Fzd1,Plk3,Tnf,Ifi204,Daxx,Mdfic,Cited2,Atf3,Phf6,Ifi207,Rbbp8,Pml,Arid5a,Nck1,Zfp281,Mxd1,Prdm1,Mafk,Ikzf1,Met,Zhx2,Notch2,Jdp2,Egr1,Kmt5a,Mtdh,Rbl1,Dnajb4,Dr1,Eno1,Txn1,Gclc,Bcl6,Max,Ifi214,Arid5b,Ppp1r15a,Ednrb,Junb |
| 2.358e-08 | -17.56 | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN | 180 | 38 | 15632 | 1249 |
Egr2,Rhoq,Pdpn,Sqstm1,Rapgef5,Plac8,Hspa1a,Timp1,Tnfaip3,Nek6,Prdm1,Slc30a4,Malt1,Arrdc4,Upp1,Kat2b,Zfp36,Cysltr2,Etv6,Egln3,AA467197,Rapgef2,Gja1,Slc13a3,Plek,Vps54,Serpine1,Gem,Ppp1r15a,Polr2g,Jak2,Il1rn,Socs3,Fndc3a,Cd200,Ptprj,Smox,Cox18 |
| 2.358e-08 | -17.56 | GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_UP | MSigDB lists | GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_UP | 180 | 38 | 15632 | 1249 |
Tle3,Ppfibp1,Mdfic,Clcn5,Cd38,Fbxo4,Batf,Rab19,Fas,Marcksl1,Malt1,Arhgap26,Tnfsf8,Fut8,Tnc,Abcb1a,Bcl6,Casp1,Gadd45b,Hivep2,Trim36,Pkp4,Ttc39b,Cxcl10,Kcna3,Ell2,Oas1g,Cd200,Endod1,Stx11,Snx2,Il12rb1,Oas1a,Plscr1,Pdlim7,Cysltr2,Casp4,Samsn1 |
| 2.368e-08 | -17.56 | response to decreased oxygen levels | biological process | GO:0036293 | 218 | 39 | 20694 | 1406 |
Sirt1,Il18,Bnip3,Myc,Notch1,Birc2,Edn1,Itpr1,Plat,Prkce,Vasn,Hmox1,Rgcc,Egr1,Cav1,Pgk1,Plau,Adrb2,Cpeb4,Slc9a1,Cd38,Pdk3,Bmp2,Ddit4,Pml,Casp1,Hif1a,Flt1,Plekhn1,Kdr,Higd1a,Ak4,Vegfc,Cited2,Mecp2,Atm,Plk3,Nos2,Fam162a |
| 2.373e-08 | -17.56 | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN | MSigDB lists | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN | 195 | 40 | 15632 | 1249 |
Ccl22,Ciapin1,Cd14,Gclc,Rras2,Sod2,Ppp1r14b,Hsph1,Dnaja1,Myc,Cish,Mdn1,Tnc,Stat3,Gadd45g,Stk40,Ppa1,Ldha,Ell2,Socs3,Hmgcs1,Itga9,Idi1,Ldlr,Thbs1,Cxcl1,Nfil3,Pmepa1,Pgk1,Tfec,Cdkn1a,Esd,Gja1,Lcn2,Cacybp,Phlda1,Rhou,Eef1e1,Tmem176a,Slc39a14 |
| 2.445e-08 | -17.53 | negative regulation of RNA biosynthetic process | biological process | GO:1902679 | 1205 | 132 | 20694 | 1406 |
Nfkb1,Relb,Cav1,Klf7,Zmynd15,Psmd10,Cdk5r1,Nr4a3,Ahr,Ifi209,Ccnd1,Ifi205,Sqstm1,Riox2,Ptch1,Irf8,Trib3,Hhex,Hmga2,Il1b,Rfx5,Mdm2,Btg2,Sirt1,Etv3,Klf3,Sap30,Ciita,Ahrr,Ifi213,Kdm4a,Nfil3,Hif1a,Zbtb5,Rel,Bmp2,Mier3,Cd38,Timeless,Cdyl,Dusp5,Nmral1,Jdp2,Zhx2,Notch2,Egr1,Rbl1,Kmt5a,Mtdh,Dr1,Eno1,Dnajb4,Gclc,Txn1,Arid5b,Ifi214,Bcl6,Max,Junb,Ppp1r15a,Ednrb,Fzd1,Jun,Tcf4,Ifi204,Daxx,Mdfic,Plk3,Tnf,Cited2,Rbbp8,Pml,Phf6,Atf3,Ifi207,Arid5a,Prdm1,Zfp281,Nck1,Mxd1,Met,Ikzf1,Mafk,Hat1,Cdyl2,Klf8,Foxp4,Prdx5,Bcor,Gfi1,Notch1,Mndal,Ifi211,Znfx1,Parp9,Ifi208,Gbp4,Pdgfb,Jarid2,Ifi203,Ccne1,Nfkbie,Hcls1,Nr3c1,Src,Nsd3,Klf2,Spen,Edn1,Tle3,Nr1h3,Etv6,Kdm5b,Zeb1,Myc,Zfp36,Ptpn2,Cebpd,Aebp2,Slfn1,Hopx,Mecp2,Cenpj,Arid4a,Ets2,Hspa1a,Ezr,Dach1,Tnfsf4,Hinfp,Hdac1,Irf1 |
| 2.445e-08 | -17.53 | transcription regulator activity | molecular function | GO:0140110 | 1333 | 145 | 20217 | 1400 |
Med21,Taf4b,Prdm9,Mecp2,Etv6,Bcor,Tfec,Klf2,Plagl2,Nr4a1,Nr1h3,Sirt1,Bcl9,Ier2,Spen,Max,Relb,Irf4,Zhx2,Hinfp,Etv5,Ccnd1,Ncoa7,Ifi203,Plscr1,Cdyl,Rel,Egr2,Kmt5a,Irf8,Stat5a,Fubp1,Hmga2,Ikzf1,Sap30,Spic,Gfi1,Ifi205,Hhex,Tcf4,Pml,Rfx5,Myc,Maff,Stat3,Jmjd6,Eno1,Stat1,Etv3,Mier3,Zbtb5,Psip1,Stat2,Rap2c,Ahr,Hivep2,Irf1,Fosb,Nfkb1,Maml2,Parp9,Pbx1,Irf7,Prdm1,Mafk,Hdac1,Med13,Riox2,Cebpd,Aff1,Pou3f1,Ifi211,Rbpms,Fos,Zeb1,Mxd1,Sqstm1,Pttg1,Ifi214,Daxx,Nsd3,Dach1,Zfp513,Mycl,Kdm5b,Nr4a3,Nupr1,Mafg,Tle3,Trib3,Helz2,Arid5b,Jdp2,Aebp2,Bcl6,Jarid2,Ifi208,Stat4,Batf2,Birc2,Hif1a,Pcgf5,Hmga1,Ifi207,Rbbp8,Pou2f2,Batf,Nfkb2,Nfxl1,Lhx2,Ifi204,Ifi213,Nfil3,Jun,Ets2,Phf6,Csrnp1,Cenpj,Klf7,Egr3,Nr3c1,Cdyl2,Junb,Klf8,Cited2,Ifi209,Tal2,Btg2,Zfp281,Plagl1,Mtdh,Mndal,Klf3,Klf6,Arid5a,Notch1,Nmi,Irf2,Foxp4,Znfx1,Hspa1a,Kat2b,Egr1,Dr1,Atf3 |
| 2.473e-08 | -17.52 | Rheumatoid arthritis | KEGG pathways | ko05323 | 82 | 25 | 7931 | 713 |
Il18,Ccl2,Flt1,Fos,Ccl5,Ccl12,Csf1,Icam1,Il1b,H2-Eb1,Il15,Il1a,H2-Ab1,Il6,Jun,Ccl3,Itgal,Tlr2,Acp5,Angpt1,Cd80,H2-Aa,Cd86,Tnf,Atp6v1d |
| 2.473e-08 | -17.52 | Rheumatoid arthritis | KEGG pathways | mmu05323 | 82 | 25 | 7931 | 713 |
Il18,Ccl5,Fos,Flt1,Ccl2,Csf1,Ccl12,Il6,H2-Ab1,Il1a,Il15,Il1b,H2-Eb1,Icam1,Ccl3,Jun,Angpt1,Tlr2,Acp5,Itgal,Cd86,H2-Aa,Cd80,Atp6v1d,Tnf |
| 2.489e-08 | -17.51 | GO_RESPONSE_TO_TOXIC_SUBSTANCE | MSigDB lists | GO_RESPONSE_TO_TOXIC_SUBSTANCE | 226 | 44 | 15632 | 1249 |
Fas,Slc30a1,Sdc1,Prdx1,Ciita,Ahr,Sod2,Ass1,Ccl12,Slc7a11,Eif2ak2,Fos,Il6,Pla2g4a,Nqo1,Lyn,Ccl4,Jak2,Cdkn1a,Abtb2,Casp8,Slc9a1,Srxn1,Nupr1,Slc30a4,Hif1a,Txnrd1,Casp3,Gsr,Prdx5,Mdm2,Kdm5b,Hp,Kdm6b,Ptgs2,Il1b,Ccl5,Slc7a8,Pdgfrb,Asns,Cnp,Ppp1r15a,Scn1b,Rab10 |
| 2.506e-08 | -17.50 | positive regulation of CD4-positive, alpha-beta T cell activation | biological process | GO:2000516 | 35 | 14 | 20694 | 1406 |
Tnfsf4,Cd83,Nlrp3,Il18,Irf1,Malt1,Socs1,Il4ra,Il2rg,Nfkbid,Ripk2,Hlx,Nfkbiz,Il6 |
| 2.531e-08 | -17.49 | GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | 45 | 17 | 15632 | 1249 |
Ap3b1,Il12rb1,Irf4,Pnp2,Il6,Cd86,Bcl6,Syk,Cd83,Il27,Cd80,Il12b,Nlrp3,Il4ra,Hlx,Tnfsf4,Ripk2 |
| 2.531e-08 | -17.49 | host cell cytoplasm | cellular component | GO:0030430 | 17 | 10 | 20747 | 1409 |
Irgm2,Gbp2b,Gbp2,Gbp9,Gbp7,Iigp1,Gbp8,Sco1,Gbp3,Pf4 |
| 2.531e-08 | -17.49 | host cell cytoplasm part | cellular component | GO:0033655 | 17 | 10 | 20747 | 1409 |
Gbp3,Pf4,Gbp8,Sco1,Iigp1,Gbp7,Irgm2,Gbp2,Gbp2b,Gbp9 |
| 2.542e-08 | -17.49 | inactivation of MAPK activity | biological process | GO:0000188 | 17 | 10 | 20694 | 1406 |
Dusp2,Spred3,Dusp8,Cav1,Dusp5,Dusp16,Dusp1,Dusp6,Spred1,Dusp4 |
| 2.568e-08 | -17.48 | GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP | MSigDB lists | GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP | 188 | 39 | 15632 | 1249 |
Hk2,Kctd12,Cnn3,Plscr1,Klf2,Zc3h12c,Ccr1,Myadm,Plaur,Nfil3,Clic4,Tmem123,Pim1,Lyn,Map3k8,Slc31a1,Ctsc,Myc,Prkce,Rgs14,Homer1,Serp1,Tpst1,Tcf4,Mgat1,Tiparp,Plac8,Syk,Casp1,Cd38,Hck,Ciita,Gbp3,Sell,Hhex,Itga4,Ube2e1,Pml,Mcoln2 |
| 2.623e-08 | -17.46 | positive regulation of myeloid leukocyte differentiation | biological process | GO:0002763 | 64 | 19 | 20694 | 1406 |
Casp8,Cd74,Ccr1,Il12b,Hcls1,Gpr68,Pf4,Ikzf1,Kitl,Trib1,Jun,Notch2,Fos,Stat5a,Ccl5,Csf1,Tnf,Ccl3,Lif |
| 2.636e-08 | -17.45 | anatomical structure morphogenesis | biological process | GO:0009653 | 2216 | 215 | 20694 | 1406 |
Inhba,Flrt3,Bcor,Spint2,Errfi1,Crkl,Akt3,Mthfd1l,Gpc1,Flt1,Dst,Pdgfb,Lif,Dock10,Map2k1,Snx10,Lst1,Egr3,Src,Stat3,Bcl2l11,Sema3c,Nr3c1,Csf1,Col18a1,Spry2,Csrnp1,Triobp,Ntng2,Antxr1,Klf2,Kdm5b,Prkx,Zeb1,Rac3,Ptk2,Fzd5,Pdgfrb,Myc,Pdpn,Hopx,Pnpt1,Stat5a,Kif5c,Tnc,Socs3,Ppp2r1b,Phactr4,Vegfc,Tulp3,Sdc2,Ccl2,Evl,Apaf1,Cdk5r1,Nr4a3,Casp3,Itgav,Cemip2,Gja1,Hmga2,Ppp2r3a,Tet2,Pdgfc,Palld,Acp5,Mdm2,Ttc39c,Lox,Jag1,Vasp,Cflar,Itga5,Hif1a,Il6,Nfkb2,Bmp2,Sema4a,Lhx2,Nrp2,Thbs1,Rab10,Notch2,Calcrl,Zhx2,Ext1,Vcam1,Tmem67,Clic4,Kdm6b,Agrn,Slc4a7,Psmb10,Plod3,Bcl6,Ifitm1,Cx3cl1,Egr2,Kdr,Sik3,Col11a2,Sdc4,Casp8,Pikfyve,Acvrl1,Met,Serp1,Zfp281,Ift57,Hmox1,Tlr2,Foxp4,Flnb,Tdrd7,Notch1,Pid1,Gfi1,Zc3h12a,Il18,Tiparp,Tmod3,Hlx,Lrp4,Stk40,Rilpl1,Mthfr,Scn1b,Spred1,Ldlr,Ptprj,Micall2,Casp1,Map4k4,Lrp8,Serpine1,Frmd6,Flrt2,Edn1,Tsku,Sema4c,Socs7,Clic5,Itgb8,Sav1,Ccr3,Nectin2,Mmp14,Itga4,Adora2a,Ets2,Mmp13,Lnpk,Plpp3,Ptger4,Acvr1,Intu,Nr4a1,Cnp,Il10,Adgrg6,Plau,Hdac1,Ahr,Pbx1,Cav1,Chst11,Klf7,Tmeff1,Htr2b,Ptch1,Lmo4,Dbnl,Pik3r6,Hhex,Txnrd1,Axl,Sirt1,Csrp1,Fam20c,Ptgs2,Abr,Casz1,Cyfip1,Atm,Nes,Timeless,Uchl1,Jmjd6,Tshz1,Nox1,Wars,Fgr,Igf1r,Tnfaip2,Actb,Junb,Sec24b,Col27a1,Rpgrip1l,Arid5b,Tnf,Snx2,Jun,Fzd1,Stxbp1,Syk,Pde3b,Cited2,Eya4,Ccl12,Pml,Ikzf1,Angpt1,Col4a2,Prdm1 |
| 2.687e-08 | -17.43 | IRF2_01 | MSigDB lists | IRF2_01 | 117 | 29 | 15632 | 1249 |
Rel,Osm,Psmb8,Xaf1,Syne2,Med13,Tmem229b,Cxcl10,Pcgf5,Il15ra,5430427O19Rik,Psmb9,Casz1,Gsdmd,Tapbp,Prdx5,Ifnb1,Bbx,Usp18,Ddx58,Pigv,Dtx3l,Psme1,Atf3,Lif,Pdgfc,Dnase1l3,Tap1,Il27 |
| 2.755e-08 | -17.41 | TTCYNRGAA_STAT5B_01 | MSigDB lists | TTCYNRGAA_STAT5B_01 | 299 | 53 | 15632 | 1249 |
Gmppb,Sdc1,Plagl1,Ccnd2,Nek6,Palld,Usp25,Aff1,Extl2,Zyx,Dock4,Tet2,Ccl12,Flt1,Dusp4,Il18bp,Irf4,Tmod3,Itpkc,Dtx2,Nfil3,Prkar2b,Irf8,Ccdc25,Plscr1,Bcl9,Sertad3,Icam1,Tab2,Apba1,Lif,Irf2,Prdm1,Olfml3,Tsku,Rgs3,Etv5,Batf,Bcl6,Birc2,Abcc5,Mecp2,Cish,Rffl,Nr4a3,Osm,Lcp2,Ccl5,Map4k4,Ppp2r3a,Dgka,Maff,Vasn |
| 2.759e-08 | -17.41 | GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP | MSigDB lists | GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP | 181 | 38 | 15632 | 1249 |
Tnfaip3,Tnfrsf14,Cd83,Pfkfb3,Arl4a,Socs1,Upp1,Fpr2,Ier2,Plk3,Arhgap26,Sat1,Bcl6,Dusp1,Nfkbia,Nfil3,Il1b,Trem1,Nfkb2,Rgs1,Cxcl1,Fpr1,Trib1,Socs3,Dusp5,Hp,Egr3,Rnf19b,Stx11,Vasp,G3bp2,Zfp36,Ddit4,Fosb,P2ry2,Ppp1r15a,Nampt,Junb |
| 2.759e-08 | -17.41 | GSE7460_TREG_VS_TCONV_ACT_UP | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_UP | 181 | 38 | 15632 | 1249 |
Slc44a1,Slc15a3,Cers6,Dusp4,Cpd,Spsb1,Tank,Sdc4,Cd38,Tnfaip3,Gbp2,Nfkbiz,Mxd1,Egr1,Rhoh,Tab2,Icam1,Plagl1,Atp11a,Phip,Ppm1l,Gbp3,Ube2l6,Plscr1,Stx11,Cd69,Myadm,Cd274,Gbp7,Gem,Cldnd1,Tnfsf10,Sec24a,Rgs1,Pmepa1,Stat1,Dusp5,Lyn |
| 2.786e-08 | -17.40 | YAGI_AML_WITH_T_8_21_TRANSLOCATION | MSigDB lists | YAGI_AML_WITH_T_8_21_TRANSLOCATION | 324 | 56 | 15632 | 1249 |
Timeless,Etv6,Pou2f2,Nfkb1,Rel,Cav1,Orai2,Fscn1,Asf1a,Tnfaip2,Abcc1,Tnfsf4,Cd200,Socs3,Ptgir,Mppe1,Rcn1,Ap3b1,Sqstm1,Agrn,Tspan3,Ciita,Cd34,Dusp14,Abr,Nck1,Cdkn2d,Plagl1,Sap30,H2-Aa,Uba7,Arid4a,Fzd5,Med21,Sipa1l1,Cldnd1,Ikbke,Acp2,H2-Ab1,Traf3ip2,Ak4,Il2rg,Arid5b,Ly75,Ccnd1,Hdac1,Cers6,Gypc,Txnrd1,Swap70,Itpr1,Csf3r,Crlf3,Sla,Nupr1,Cd74 |
| 2.816e-08 | -17.39 | response to exogenous dsRNA | biological process | GO:0043330 | 58 | 18 | 20694 | 1406 |
Cav1,Mul1,Ripk2,Ifnb1,Ifna4,Nod2,Ddx58,Ifih1,Tlr3,Stat1,Ifna5,Ifna2,Zc3hav1,Cgas,Irak3,Ifna6,Nfkbia,Ifna1 |
| 2.819e-08 | -17.38 | MODULE_321 | MSigDB lists | MODULE_321 | 104 | 27 | 15632 | 1249 |
Myc,Ctsc,Gclm,Itgav,Slc16a3,Klf6,Cnn2,Lpcat2,Gbe1,Ccnd2,Prnp,Nek6,Col18a1,Fas,Phlda1,Ext1,Nrp2,Procr,Casp4,Psmb8,Lrrc8c,Nfil3,Dcbld2,Lrp11,Adora2b,Itga5,Ldha |
| 2.820e-08 | -17.38 | GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 124 | 30 | 15632 | 1249 |
Cd55,Hmox1,Mmp9,Il18,Il15ra,S100a8,Ifit1bl2,Plekha4,Igsf8,Gbgt1,Trim56,Irf2,Evl,Hhex,Itga4,Pml,Ciita,Extl2,Slfn5,Cnn2,Cx3cr1,Ifit1bl1,Lipe,Cyfip1,Rhbdf2,Csf3r,Ctsc,Cp,Stard5,Ccnd1 |
| 2.848e-08 | -17.37 | GO_POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | 152 | 34 | 15632 | 1249 |
Htr2a,Cd80,Il15,Angpt1,Tnfrsf14,Lrp8,Lif,Icam1,Cd74,Stap1,Il6,Stat3,Syk,Lrp4,Hsph1,Src,Cd40,Hcls1,Kitl,Clcf1,Jak2,Vegfc,Ripk2,Socs3,Itga5,Ptger4,Il12b,Il18,Lyn,Pdgfb,Rictor,Csf3,Ccl5,Osm |
| 2.853e-08 | -17.37 | regulation of CD4-positive, alpha-beta T cell differentiation | biological process | GO:0043370 | 52 | 17 | 20694 | 1406 |
Socs1,Ripk2,Hlx,Il4ra,Il2rg,Nfkbid,Il6,Nfkbiz,Tnfsf4,Cd83,Nlrp3,Zc3h12a,Malt1,Irf1,Il18,Bcl6,Il27 |
| 2.853e-08 | -17.37 | STAT_01 | MSigDB lists | STAT_01 | 227 | 44 | 15632 | 1249 |
Prdm1,Apba1,Icam1,Sertad3,Batf,Etv5,Abcc5,Bcl6,Rffl,Cish,Mecp2,Nr4a3,Map4k4,Osm,Rab10,Vasn,Maff,Ppp2r3a,Usp25,Nek6,Sdc1,Ccnd2,Gmppb,Flt1,Ccl12,Tet2,Dock4,Jun,Psd,Cnot4,Il18bp,Dusp4,Itpkc,Dtx2,Tmod3,Irf1,Cacna1d,Nfil3,Dcun1d3,Irf8,Bcl9,Plscr1,Ccdc25,Il18rap |
| 2.920e-08 | -17.35 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION | MSigDB lists | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION | 31 | 14 | 15632 | 1249 |
Ifna2,Ifna1,Ikbke,Irf1,Ddx58,Ifih1,Rnf135,Irf2,Ifnb1,Ifna5,Ifna6,Traf2,Irf7,Tank |
| 2.923e-08 | -17.35 | GO_RESPONSE_TO_MECHANICAL_STIMULUS | MSigDB lists | GO_RESPONSE_TO_MECHANICAL_STIMULUS | 204 | 41 | 15632 | 1249 |
Asns,Cav1,Tnfsf14,Fosb,Ptch1,Casp8,Junb,Nfkb1,Gja1,Mmp13,Casp2,Btg2,Slc9a1,Irf1,Ptgs2,Map2k4,Cxcl10,Tlr3,Ptger4,Il1b,Lrp11,Fos,Cd40,Jun,Cnn2,Src,Nfkbia,Eif2ak2,Casp1,Ccl12,Bnip3,Tnc,Edn1,Kcnj2,Il6,Mmp14,Hif1a,Fas,Myd88,Tnfrsf8,Htr2a |
| 2.991e-08 | -17.33 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP | 189 | 39 | 15632 | 1249 |
Cd34,Samhd1,Hck,Hhex,Nek6,Cd180,Arrdc4,Pla2g4a,Rhoq,Rai14,Ogfrl1,Fgl2,Ccnd1,Rab32,Swap70,Gcnt2,Rgs1,Abcc1,Tfec,Ebi3,Endod1,Ptk2,Parp3,Acvr1b,Itga9,Ier3,Lyn,Procr,Il18rap,Tdrd7,Kctd12,Plek,Ccl5,Myadm,Dusp6,Cd86,Tnfsf14,Samsn1,Gem |
| 3.064e-08 | -17.30 | JAATINEN_HEMATOPOIETIC_STEM_CELL_DN | MSigDB lists | JAATINEN_HEMATOPOIETIC_STEM_CELL_DN | 212 | 42 | 15632 | 1249 |
Igsf6,Pnp2,Vcan,Fgl2,Cebpd,Cx3cr1,Cst7,Bcl2l11,Pik3r5,Gpr18,Cited2,Cd14,Tnfaip3,Hck,Samhd1,Cdkn2d,Upp1,Cdk5r1,Fgr,Isg20,Kctd12,Rasgrp1,Stx11,Il18rap,Ccr1,S100a8,Fcgr4,Ccl5,Klf2,Cd86,Il1rn,Serpinb2,Thbs1,Rgs1,Ccl4,Pf4,Rtn1,Il13ra1,Mmp9,Tgfbi,Ms4a6d,Fpr1 |
| 3.090e-08 | -17.29 | negative regulation of RNA metabolic process | biological process | GO:0051253 | 1292 | 139 | 20694 | 1406 |
Txn1,Gclc,Max,Bcl6,Arid5b,Ifi214,Ednrb,Ppp1r15a,Junb,Zhx2,Notch2,Jdp2,Egr1,Mtdh,Kmt5a,Larp1,Rbl1,Dnajb4,Eno1,Dr1,Ifi207,Atf3,Phf6,Rbbp8,Pml,Arid5a,Mxd1,Zfp281,Nck1,Prdm1,Mafk,Myd88,Noct,Met,Ikzf1,Tcf4,Jun,Fzd1,Plk3,Tnf,Mdfic,Ifi204,Daxx,Cited2,Trib3,Irf8,Mapkapk2,Il1b,Hmga2,Hhex,Btg2,Mdm2,Rfx5,Klf3,Etv3,Sirt1,Zmynd15,Klf7,Cav1,Relb,Nfkb1,Ccnd1,Ifi209,Ahr,Nr4a3,Psmd10,Cdk5r1,Ifi205,Sqstm1,Ptch1,Riox2,Rel,Zbtb5,Bmp2,Timeless,Cd38,Mier3,Nmral1,Dusp5,Cdyl,Ciita,Sap30,Ahrr,Ifi213,Tent4a,Nfil3,Kdm4a,Hif1a,Kdm5b,Zeb1,Etv6,Nr1h3,Tle3,Myc,Cebpd,Ptpn2,Zfp36,Nsd3,Tent2,Spen,Klf2,Edn1,Dach1,Ezr,Hinfp,Tnfsf4,Hdac1,Irf1,Aebp2,Hopx,Slfn1,Mecp2,Hspa1a,Ets2,Arid4a,Cenpj,Gfi1,Mndal,Notch1,Ifi211,Zc3h12a,Cdyl2,Hat1,Bcor,Prdx5,Foxp4,Klf8,Ccne1,Ifi203,Jarid2,Hcls1,Nfkbie,Nr3c1,Src,Parp9,Ifi208,Znfx1,Gbp4,Pdgfb |
| 3.113e-08 | -17.28 | AKT_UP_MTOR_DN.V1_UP | MSigDB lists | AKT_UP_MTOR_DN.V1_UP | 167 | 36 | 15632 | 1249 |
Rab3ip,Mvp,Hck,Atf3,Plagl1,Arrdc4,Sphk1,Edn1,Dusp8,Slc44a1,Dusp1,Flt1,Ifit1bl1,Klf6,Msr1,Sh3bgrl2,Plat,Nfkb2,Igf1r,Nfil3,Rnf19b,H2-Ab1,Ptprj,Cd55,Ak4,Adora2b,Gpd2,Pdzd11,Plscr1,S100a8,Pdk3,Junb,Ifit1bl2,Tor3a,Gch1,Plk2 |
| 3.179e-08 | -17.26 | STAT5B_01 | MSigDB lists | STAT5B_01 | 220 | 43 | 15632 | 1249 |
Ccl5,Map4k4,Irf8,Lcp2,Osm,Bcl9,Plscr1,Ccdc25,Vasn,Dgka,Maff,Dtx2,Tmod3,Itpkc,Irf1,Nr4a3,Prkar2b,Nfil3,Nfkbia,Ccl12,Fos,Bcl6,Zyx,Dock4,Irf4,Fut8,Cish,Mecp2,Psd,Irf2,Prdm1,Palld,Apba1,Nek6,Lif,Usp25,Plagl1,Sdc1,Icam1,Gmppb,Batf,Etv5,Olfml3 |
| 3.203e-08 | -17.26 | cellular response to drug | biological process | GO:0035690 | 350 | 53 | 20694 | 1406 |
P2ry12,Tnf,Aim2,Daxx,Ccl7,Atp2b4,Kdr,Ccl4,Ddit4,Slamf8,Tlr9,Serpine1,Ifnb1,Nod1,Nod2,Egr1,Larp1,Kdm6b,Myc,Bnip3,Pde4b,Actb,Nqo1,Pdgfrb,Ripk2,Cflar,Nos2,Il6,Pdgfb,Traf2,Lcn2,Thbs1,Timeless,Nr3c1,Cd69,Prnp,Src,Tnfaip3,Nfkb1,Ahr,Prkce,Hmox1,Cdk5r1,Ripk3,Sphk1,Slc31a1,Crkl,Jak2,Acod1,Axl,Il1b,Zc3h12a,Sirt1 |
| 3.224e-08 | -17.25 | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_UP | 182 | 38 | 15632 | 1249 |
Gtpbp2,Plcl2,Smc5,Rnf19b,Slc25a22,Cox18,Tmem229b,Timeless,Oas2,Stat4,Brd2,Ccnj,Pdk3,Slc12a9,Atp6v1d,Irf7,Asns,Extl2,Rnf34,Prpf38a,Ripk3,Ddx60,Ifih1,Nxf1,Nat2,Batf2,1110038F14Rik,Sat1,Rsad2,Ccng2,Atp13a1,Hdac1,Apobec3,Klf6,Birc2,Gpsm2,Rbbp8,Rgs14 |
| 3.224e-08 | -17.25 | GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 182 | 38 | 15632 | 1249 |
Csf3,Met,Hk2,Csf1,Isg20,Cnn3,Phlda1,Flnb,Sema3c,Il10,Irf8,Irf7,Casp4,Birc3,Gja1,Glrx,Frmd6,Serpinb2,Clic4,Adora2b,Ptgs2,Rnf19b,Ell2,Tnc,Cish,Plac8,Tagln,Ifnar1,Myo10,Olr1,1600014C10Rik,Pttg1,Il1a,Tmem176b,Nfkbiz,Prdm1,Slc30a4,Nupr1 |
| 3.318e-08 | -17.22 | regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001236 | 161 | 32 | 20694 | 1406 |
Serpine1,Inhba,Tnfaip3,Cav1,Icam1,Hmox1,Phip,Itgav,Sgk3,Acsl5,Il1b,Gclc,Gclm,Rffl,Cflar,Traf1,Cx3cl1,Tnf,Ppp2r1b,Rnf34,Traf2,Cx3cr1,Atf3,Pml,Casp8,Eya4,Acvr1,Tnfsf4,Thbs1,Pf4,Tnfsf10,Src |
| 3.322e-08 | -17.22 | PEDRIOLI_MIR31_TARGETS_DN | MSigDB lists | PEDRIOLI_MIR31_TARGETS_DN | 334 | 57 | 15632 | 1249 |
Slc7a11,Sod2,Sbds,Ifit1bl1,Plac8,Pla2g4a,Tmem171,Prokr1,Samd9l,Nqo1,Nod2,Nfkbiz,Cx3cl1,Vcpip1,Ednrb,Birc3,Ifit3,Tnfsf14,Trim14,Rhou,Smpdl3b,Usp12,Endod1,Tlr2,Ifit3b,Rcsd1,Chd9,Txnrd1,Slc16a3,Ifit2,Klf6,Csf3r,Mdn1,Mafk,Sele,Fgl2,Hlx,Ifih1,Icam1,Myd88,Gbp2,Tnfaip3,Relb,Cd164,Gch1,4930523C07Rik,Ifit1bl2,Flrt2,Ppm1k,Slc31a1,Cd55,Nr4a3,Irak2,Nfkb2,Cxcl1,Vcam1,Glrx |
| 3.322e-08 | -17.22 | intrinsic apoptotic signaling pathway in response to DNA damage | biological process | GO:0008630 | 78 | 21 | 20694 | 1406 |
Dyrk2,Bcl2a1a,Sirt1,Bcl2l11,Tnfrsf1b,Ier3,Myc,Ddit4,Pmaip1,Pml,Cdkn1a,Bcl2a1b,Uaca,Atm,Ifi204,Hmox1,Tnf,Nupr1,Ikbke,Bcl2a1d,Sod2 |
| 3.358e-08 | -17.21 | WANG_SMARCE1_TARGETS_DN | MSigDB lists | WANG_SMARCE1_TARGETS_DN | 309 | 54 | 15632 | 1249 |
Etv3,Plagl1,Kat2b,Il4ra,Rras2,Gng11,Tap1,Samhd1,Srm,Sod2,Hmga1,Cited2,Ctsc,Bnip3,Mid1,Dusp4,Casp7,Hmgcs1,Dennd2a,Dck,Trib1,Psmb8,S100a8,Ccne1,Sema3c,Cav1,Lap3,Alas1,Lif,Slc25a37,Hsph1,Psmb9,Oas3,Rab9,Ogfrl1,B3gnt5,Ptger4,Uchl1,Spata5l1,Cxcl1,Bambi,Slc4a7,Dusp6,Gdf15,Cacybp,Tap2,Plk2,Higd1a,Tmeff1,Bst1,AA467197,Cxcl2,Parp12,Hk2 |
| 3.386e-08 | -17.20 | GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 153 | 34 | 15632 | 1249 |
Map3k8,Il18,Frmd4a,Ifit3b,Tlr2,St3gal1,Tlr3,Socs3,Rac3,Plaur,Notch2,Tnfaip2,Ifit3,Irf7,Ccl5,Psd4,Ube2e2,Met,Rasgrp1,Kctd12,Nmi,Calcrl,Ddx58,Pigv,Usp25,Enpp4,Myo10,Arid5a,Spic,Csf3r,Rin2,Acvrl1,Pde5a,Stard5 |
| 3.413e-08 | -17.19 | GNF2_CD33 | MSigDB lists | GNF2_CD33 | 51 | 18 | 15632 | 1249 |
Ier2,Ms4a6d,Tlr2,Nlrp3,Tnfaip2,Cd14,Fcgr1,Hk3,Dusp1,Dusp6,Casp1,Fos,Cd302,Vcan,Bst1,Nod2,Fgl2,Stx11 |
| 3.436e-08 | -17.19 | regulation of cell cycle | biological process | GO:0051726 | 958 | 110 | 20694 | 1406 |
Pdgfrb,Gadd45g,Myc,Birc2,Edn1,Trim21,Trip13,Hspa2,Pkp4,Nupr1,Ccng2,Irf1,Hinfp,Nr4a1,Il10,Dach1,Cenpj,Hspa1a,Cenpe,Phactr4,Dcun1d3,Atp2b4,Mecp2,Slfn1,Pnpt1,Pdpn,Stat5a,Notch1,Chmp4b,Sphk1,Pim1,Tnfaip3,Inhba,Src,Stat3,Bcl2l11,Asns,Map2k1,Ccne1,Pdgfb,Nek6,Lif,Tmod3,Smc5,Junb,Actb,Gadd45b,Il12b,Parp3,Tmem67,Dync1h1,Phip,Rbl1,Igf1r,Ankrd17,Ube2e2,Rgcc,Cdkn2d,Kat2b,Notch2,Met,Asah2,Ccnj,Ccl12,Pml,Cdkn1a,Plaat3,Cited2,Tpx2,Il1a,Tnf,Plk3,Trim36,Jun,Sirt1,Psme1,Ier3,Gpr132,Mdm2,Btg2,Hhex,Hmga2,Pim3,Il1b,Gpsm2,Pttg1,Casp3,Ptch1,Cdk5r1,Psmd10,Prkce,Nr4a3,Pbx1,Ccnd1,Osm,Crlf3,Hspa1b,Fbxo4,Sde2,Whamm,Prdm9,Plk2,Timeless,Thbs1,Bmp2,Casp2,Psme2,Ccnd2,Atm,Ptgs2 |
| 3.441e-08 | -17.18 | SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | MSigDB lists | SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | 62 | 20 | 15632 | 1249 |
Ifi211,Stat3,Ifi208,Inhba,Ifi203,Spint2,Plac8,Ifi213,Armcx6,Mndal,Ifi209,Ifi205,Thbs1,Ifi207,Pmepa1,Stat1,Il13ra1,Uchl1,Ifi204,Ifi214 |
| 3.472e-08 | -17.18 | GO_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | MSigDB lists | GO_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | 146 | 33 | 15632 | 1249 |
Glipr2,Nod2,Il6,Ccl2,Spry2,Jun,Ccl12,Src,Tnf,Ccl3,Angpt1,Pdgfc,Bmp2,Htr2a,Nod1,Cx3cl1,Icam1,Ccl22,Cd74,Rasgrp1,Rapgef2,Pdgfb,Cysltr2,Pdgfrb,Ccl5,Ccr1,Il1b,Htr2b,Ccl4,Kdr,Gcnt2,C3,Ripk2 |
| 3.479e-08 | -17.17 | GSE43955_1H_VS_20H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_1H_VS_20H_ACT_CD4_TCELL_UP | 190 | 39 | 15632 | 1249 |
Hck,Aff1,Adar,Clec4e,Pnpt1,Batf,Nr1h3,Slc30a1,Il4ra,Ch25h,Evl,Ier2,Prdx5,Bcl2a1d,Mdm2,Il4i1,Il6,Ikzf1,Cited2,Msr1,Ppp1r14b,Bcl2a1b,Aoah,Tnf,Dusp16,Tnip1,Bcl2a1a,Cxcl1,Dr1,Il1rn,Rtn1,Maff,Ppp4r2,Gpr132,Cep350,Ppp1r15a,Mov10,Ednrb,Gch1 |
| 3.491e-08 | -17.17 | regulation of neuron apoptotic process | biological process | GO:0043523 | 266 | 44 | 20694 | 1406 |
Atm,Nes,Hif1a,Mt1,Hsph1,Cpeb4,Nr3c1,Prnp,Bcl2l11,Casp2,Jak2,Casp3,Clcf1,Nr4a3,Hmox1,Cdk5r1,Optn,Btg2,Il18,Sirt1,Axl,Pmaip1,Il1b,Mecp2,Stxbp1,Kdr,Jun,Sod2,Egln3,Cx3cl1,Tnf,Ccl3,Adora2a,Hdac1,Angpt1,Cx3cr1,Ccl12,Map2k4,Egr1,Fas,Gclm,Nqo1,Agrn,Gclc |
| 3.527e-08 | -17.16 | DUNNE_TARGETS_OF_AML1_MTG8_FUSION_DN | MSigDB lists | DUNNE_TARGETS_OF_AML1_MTG8_FUSION_DN | 27 | 13 | 15632 | 1249 |
Ifi214,Ifi204,Ifi207,Cd34,Ifi209,Mndal,Ifi205,Samsn1,Dusp6,Ifi213,Ifi203,Ifi208,Ifi211 |
| 3.550e-08 | -17.15 | GNF2_CBFB | MSigDB lists | GNF2_CBFB | 36 | 15 | 15632 | 1249 |
Hdac1,Ifi203,Ifi211,Ifi208,Ifi205,Ifi209,Mndal,Psmb8,Ifi213,Ifi207,Polr2g,Ifi204,Fam111a,Ifi214,Psmb10 |
| 3.550e-08 | -17.15 | GO_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | MSigDB lists | GO_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | 36 | 15 | 15632 | 1249 |
Ripk2,Tnfsf4,Cd55,Hlx,Il4ra,Nlrp3,Il12b,Cd80,Il27,Cd83,Bcl6,Cd86,Il6,Irf4,Il12rb1 |
| 3.585e-08 | -17.14 | GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 948 | 123 | 15632 | 1249 |
Junb,Nampt,Klf2,Pdgfb,Ptger4,Ptgs2,Serpinb9,Ptafr,Bambi,Gng12,Src,Ehd1,Dusp1,Lrp4,P2ry12,Fut8,Nr3c1,Rhoq,Mdm2,Acvr1,Kdm5b,Acvrl1,Pml,Icam1,Hif1a,Agtrap,Socs1,Nod1,Bmp2,Daxx,Notch1,Ltbp2,Ccne1,Il10,Casp4,P2ry2,Sirt1,Tnfsf4,Acsl1,Igf1r,Prkar2b,Socs7,Cx3cr1,Ezr,Ccl12,Flrt3,Fos,Zyx,Jun,Edn1,Il6,Prkce,Nod2,Egr1,Phip,Plau,Gng11,Pde3b,Atp2b4,Pde4b,Gdf15,Ccl5,Ppp1r15a,Asns,Flrt2,Atp6v1d,Fosb,Pdgfrb,Rab10,Inhba,Rapgef2,Sh3bp4,Fzd1,Ripk2,Gng4,Trib3,Nr4a3,Gcnt2,Htr2b,Il1b,Tnf,Stat5a,Klf6,Plod3,Stat3,Tnc,Errfi1,F11r,Gnb4,Pdgfc,Apaf1,Rnf14,Nfkb1,Cav1,Pid1,Plod2,Slc9a1,Zeb1,Med13,Hmgcs1,Cpeb4,Ptk2,Max,Egr3,Lyn,Polr2g,Gfpt1,Jak2,Pmepa1,Klf3,Nr4a1,Ass1,Syk,Dnaja1,Ptpn2,Ifnb1,Fas,Kat2b,Irs2,Nr1h3,Col4a2,Spred1,Ahr |
| 3.597e-08 | -17.14 | chemical homeostasis | biological process | GO:0048878 | 1108 | 123 | 20694 | 1406 |
Slc30a4,Hk2,Slc39a4,Ptch1,Itpr1,Htr2b,Itgav,Gja1,Cav1,Klf7,Slc7a11,Prkce,Slc31a2,Ttc39b,Sirt1,Grina,Il1b,Tmtc2,Slc39a14,Il6,Hif1a,Rmdn3,Gna15,Slc39a13,Cd38,Mt1,Cacnb3,Dmxl2,Prnp,Clic4,Cd40,Igf1r,Atp13a1,Stxbp3,Cutc,Nox1,Vcam1,Slc16a1,Cxcl2,Ccl5,Hk1,Icam1,Lipg,Bnip3,Slc4a7,Ednrb,Fpr1,Fabp3,Gclc,Pde3b,Kdr,Cacna1d,Sod2,Mt2,Cx3cl1,Ccl3,P2ry2,Gpr35,Rab20,Met,Ccr1,Pml,Cp,Pla2g4a,Marcksl1,Slc31a1,Jak2,Stat1,Ncoa5,Cxcl3,Gpr18,Hmox1,Swap70,Il18,Hk3,Ero1l,Scn1b,1600014C10Rik,Tmem178,Mafg,Cxcl10,Lpar1,Sesn3,Src,Stat3,Fpr2,Hap1,Lcn2,Snx10,Xcr1,Ldlr,Pdk3,Sec24a,Map2k1,Stau1,Edn1,Ccrl2,Homer1,Myc,Gclm,Slc12a9,Htr2a,Ptpn2,Ptk2,Med13,Nr1h3,Ccr3,Ptgir,Ptger4,Atp2b4,Cmklr1,Tspo,Cxcl1,Ehd1,Slamf8,Slc9a1,Adrb2,Slc30a1,Gk,Ccl2,Cx3cr1,Mllt6,Sco1 |
| 3.652e-08 | -17.13 | GO_POSITIVE_REGULATION_OF_CYTOKINE_SECRETION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYTOKINE_SECRETION | 86 | 24 | 15632 | 1249 |
Htr2b,Il1b,Ptger4,Clec5a,Rasgrp1,Clec4n,Il10,Cd274,Cd34,Clec4e,Cd14,Tnfrsf14,Aim2,Il1a,Fgr,Il4ra,Nlrp3,Nod2,Src,Gsdmd,Tnf,Syk,Ifnar1,Casp1 |
| 3.717e-08 | -17.11 | MODULE_312 | MSigDB lists | MODULE_312 | 46 | 17 | 15632 | 1249 |
Fas,Il1a,Ccnd2,Ier3,Bcl2a1a,Cflar,Tnfsf10,Serpinb2,Il1b,Birc3,Dusp6,Nfkb1,Bcl2a1b,Birc2,Bnip3,Cd69,Bcl2a1d |
| 3.717e-08 | -17.11 | KHETCHOUMIAN_TRIM24_TARGETS_UP | MSigDB lists | KHETCHOUMIAN_TRIM24_TARGETS_UP | 46 | 17 | 15632 | 1249 |
Egr1,Stat1,Icam1,Col4a2,Vcam1,Cd38,Cdkn1a,Hck,Junb,Itgav,Casp1,Fos,Itgal,Serpine1,Btg2,Rai14,Cp |
| 3.761e-08 | -17.10 | GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN | MSigDB lists | GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN | 183 | 38 | 15632 | 1249 |
Morc3,Dock4,Ankrd17,Ptpn2,Itpr1,Ly75,Gadd45g,Cebpd,Ifrd1,Optn,Nfkbie,Rhoh,Hhex,Hlx,Il4ra,Trim13,Kmo,Relb,Tnfaip3,Hck,Crim1,Klf7,Rnf14,Psd4,Tor1aip1,Zfp36,Oas2,Cd69,Spint2,Cxcl2,Oas1a,Oas1g,Cd55,Kdm6b,Map3k8,Tlr2,Gca,Cxcl1 |
| 3.761e-08 | -17.10 | GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_DN | 183 | 38 | 15632 | 1249 |
Smpdl3b,Rasgrp1,Nrp2,Rab10,Trim21,Zc3h12c,Ubr4,Txn1,Ankib1,Jdp2,Rcl1,Frmd6,Jak2,Asf1a,Kcna3,Ms4a6d,Gpr85,Arid5b,Hp,Tlk2,Mdm2,Dtnb,Prdx5,Cp,Katna1,Tspan3,Traf2,Klf3,Itgav,Prpf38a,Slc28a2,Fbxo4,Spata13,Sdc1,Usp18,Kat2b,Calcrl,Magohb |
| 3.761e-08 | -17.10 | GSE38304_MYC_NEG_VS_POS_GC_BCELL_DN | MSigDB lists | GSE38304_MYC_NEG_VS_POS_GC_BCELL_DN | 183 | 38 | 15632 | 1249 |
Bcl2a1b,Apobec3,Ttc39c,Tbc1d1,B3gnt5,Bcl2a1d,Arhgap26,Mcoln2,Tpi1,Abr,Gbp3,Traf1,Gbe1,St3gal6,Pttg1,Prnp,Slamf7,Traf5,Rhoc,Hopx,Gna15,Asns,Plscr1,Cysltr2,Adora2a,Stx11,Il12rb1,Smpdl3b,Tmod3,Ell2,Endod1,Tlr3,Rab20,Mafg,Pim1,Bcl2a1a,Ap3m2,Pkp4 |
| 3.856e-08 | -17.07 | MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP | MSigDB lists | MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP | 161 | 35 | 15632 | 1249 |
Tnc,Sat1,Mmp14,Cp,Egr2,Vcan,Cpd,Ehd1,Tagln,Itgav,Slc2a1,Ets2,Lipg,Cd14,Crim1,Pdgfc,Tle3,Marcksl1,Fabp3,Arl4a,Cnn3,Htra1,Vasn,Jag1,Gja1,Hk1,Tuba4a,Ogfr,Plod2,Plat,Kdr,Dusp16,Cdkn1a,Il13ra1,Ier3 |
| 3.856e-08 | -17.07 | GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | 161 | 35 | 15632 | 1249 |
Parp8,Ogfrl1,Samd9l,Pde5a,Fut8,Pla2g4a,Gbp4,Gbp9,Calcrl,Ddx58,Papss2,Gbp3,Itga4,Aim2,Ddx60,Mcoln2,Prrg4,Rab3ip,Ncoa7,Crlf3,Snx10,Slc25a12,Tifa,Atxn7l1,Rcn1,Pik3cd,Frmd4a,Etnk1,Arl5c,Cd200,Pcgf5,Cdkn1a,Idi1,Ldlr,Chd9 |
| 3.924e-08 | -17.05 | regulation of endothelial cell proliferation | biological process | GO:0001936 | 130 | 28 | 20694 | 1406 |
Flt1,Kdr,Vegfc,Pdgfb,Tnf,Jun,Stat5a,Egr3,Acvrl1,Ccl2,Stat3,Thbs1,Nr4a1,Bmp2,Ccl12,Adora2b,Il10,Stat1,Gja1,Htr2b,Rgcc,Hmox1,Cav1,Rictor,Sirt1,Itga4,Ccr3,Akt3 |
| 3.935e-08 | -17.05 | positive regulation of cytokine production involved in immune response | biological process | GO:0002720 | 53 | 17 | 20694 | 1406 |
Fzd5,Malt1,Il18,Arid5a,Il1b,Tnfsf4,Nlrp3,Cd74,Traf2,Il6,Ddx58,Nr4a3,Hk1,Tlr2,Tnfrsf14,Nod2,Rsad2 |
| 4.009e-08 | -17.03 | GO_REGULATION_OF_SECRETION | MSigDB lists | GO_REGULATION_OF_SECRETION | 650 | 92 | 15632 | 1249 |
Irs2,Nr1h3,Cx3cl1,Slc30a1,Sdc1,Stxbp1,Slc16a1,Clec4e,Pim3,Cd34,Sdc4,Syk,Gsdmd,Lyn,Tlr9,Jak2,Nos2,Ednrb,S100a8,Cd74,Aim2,Cd38,Cd14,Serp1,Rhbdf2,Traf2,Tnf,Rsad2,Gpr68,Rab11fip1,Rab21,Adora2b,Hmox1,Htr2b,Il1b,Sec24a,Osm,Cd274,Ccl5,Gja1,H2-Eb1,Inhba,Mmp13,Stxbp3,Nlrp3,Il4ra,Tlr6,Abr,Angpt1,Tnfrsf14,Htr2a,Ezr,Nod2,Il6,Prkce,Edn1,Tlr2,Tnfsf4,Nlgn2,Pfkl,Cacna1d,P2ry2,Rims3,Il10,Clec4n,Rabgef1,Rasgrp1,Sphk1,Socs1,Fgr,Il1a,Hif1a,Pml,Lif,Notch1,Cd40,Slc2a1,P2ry12,Itpr1,Casp1,Ifnar1,Src,Kdm5b,Rab9,Ptafr,Clec5a,Zc3h12a,Ptger4,Hcar2,Vegfc,Hap1,Tlr1 |
| 4.019e-08 | -17.03 | positive regulation of cysteine-type endopeptidase activity | biological process | GO:2001056 | 138 | 29 | 20694 | 1406 |
Sirt1,Malt1,Myc,Nlrp3,Mefv,Pmaip1,Nlrc4,Stat1,Jak2,Uaca,Fas,Nod1,Cycs,Bcl2l11,Tnfsf10,Ift57,Apaf1,Casp4,Pml,Casp1,Casp8,S100a8,Syk,Aim2,Tnf,Tnfsf15,Fam162a,Mul1,Ripk2 |
| 4.019e-08 | -17.03 | cellular response to tumor necrosis factor | biological process | GO:0071356 | 138 | 29 | 20694 | 1406 |
Nfkb1,Ccl5,Fas,Jak2,Acod1,Stat1,Birc2,Pid1,Ccl9,Ccl8,Ccl22,Tnfrsf1b,Zc3h12a,Zfp36,Sirt1,Tnf,Cx3cl1,Aim2,Ccl7,Ccl3,Il6,Ccl4,Traf2,Birc3,Ccl12,Nfkbia,Ccl2,Tank,Irf1 |
| 4.039e-08 | -17.02 | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 176 | 37 | 15632 | 1249 |
Tnfaip3,Ahsa1,Ube2f,Slc30a1,Upp1,Mapkapk2,Egr1,Csrnp1,Ythdf1,Mdm2,Dusp8,Dusp2,Dennd1b,Tbc1d1,Spry2,Serp1,Bcl6,Sqstm1,Hsph1,Nr4a1,Gadd45b,Stip1,Dusp16,Azi2,Pim1,Dyrk2,Cxcl2,Nfkbid,Phlpp2,Arl5b,Med13,Gem,Plk2,Tnfrsf1b,Dusp6,Jarid2,Hsd17b12 |
| 4.041e-08 | -17.02 | GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_UP | MSigDB lists | GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_UP | 191 | 39 | 15632 | 1249 |
Wars,Rapgef2,Ccrl2,Hk2,Maff,Psme2,Gem,Eno2,Txn1,Slc31a2,S100a8,P4ha1,Pgk1,Cdkn1a,Snapc1,Bcl2a1a,Cflar,Cldnd1,Adam19,Adora2b,Arid5b,Mthfd2,Cd55,Ldha,Phlpp1,Ifrd1,Bcl2a1d,Dusp4,Nr3c1,Jun,Ets2,Gpsm2,Ezr,Klf6,Bcl2a1b,Fcgr1,Prnp,Ccnd2,Rnf139 |
| 4.136e-08 | -17.00 | GO_ENZYME_BINDING | MSigDB lists | GO_ENZYME_BINDING | 1618 | 188 | 15632 | 1249 |
Pml,Mcm10,Fgr,Sell,Sphk1,Daxx,Ppp6r1,Lrp4,Lipe,Eno1,Timp1,Carhsp1,Rffl,Acvrl1,Uchl1,Ptprj,Ptgs2,Dio2,Tuba4a,Snx10,Dmxl2,Etv3,Pde3b,Hinfp,Nfkbia,Jun,Cyfip1,Ppp2r5a,Spry2,Triobp,Acvr1b,Hcls1,Prkar2b,Rnf31,Ankib1,Plscr1,Rnf139,Tulp3,Cd74,Traf5,Tnfaip3,Tnf,Zmynd15,Traf2,Hspa2,Errfi1,Hdac1,Sele,Phf6,Trib3,Ppp2r2a,Plek,Ppp1r15a,Tbc1d13,Sh3bp4,Stxbp1,Nck1,Irs2,Tpx2,Mul1,Syk,Sqstm1,Dnaja1,Stap1,Tor1aip2,Phactr4,Ap3b1,Ptk2,Lyn,Trib1,Ldlr,Whamm,Jak2,Cdkn1a,Vrk2,Dcun1d3,Ikbkg,Casp8,Cenpj,Slpi,Slc9a1,Rhoh,Malt1,Traf1,Trim12c,Socs1,Kdm4a,Hif1a,Smg7,Bfar,Notch1,Ehd1,Src,Tank,Hspa1a,Slc2a1,Cd40,Rgs14,Egr2,Casp3,Tbc1d1,Mlkl,Ccnd1,Mdm2,Ldha,Rnf19b,Ptafr,Serpinb9,Fmnl2,Plaur,Daam1,Ranbp2,Adora2a,Csf3,Egr1,Ccnd2,Cdc42ep2,Tnks1bp1,Angpt1,Atp2b4,Tnfrsf14,Ezr,Dock4,Prkce,Nod2,Stat1,Nox1,Adrb2,Tnip1,Cflar,Actb,Pfkl,Ccne1,Rabgef1,Ksr1,Casp2,Met,Rnf19a,Sirt1,Prdm1,Gys1,Ube2f,Rnf34,Mvp,Stau1,Rab11fip1,Stat3,Micall2,Mecp2,Hmox1,Nr4a3,Cdc42ep4,Ikbke,Map2k1,Pdgfrb,Serpine1,Tor1aip1,Fzd5,Nek6,Bcor,Cdkn2d,Usp25,Tpi1,Fas,Cdk5r1,Kat2b,Sdc4,Spred1,Rnf114,Itgav,Ptpn2,Hmga1,Cited2,Dusp2,Pla2g4a,Bnip3,Ctsc,Gclm,Mid1,Optn,Cacnb3,Tax1bp1,Dnajb2,Tnfrsf1b,Rnf14,Cav1,Zfp36,Rictor |
| 4.147e-08 | -17.00 | BIOCARTA_HIVNEF_PATHWAY | MSigDB lists | BIOCARTA_HIVNEF_PATHWAY | 57 | 19 | 15632 | 1249 |
Fas,Casp7,Ptk2,Traf1,Cflar,Apaf1,Daxx,Birc3,Tnf,Nfkbia,Nfkb1,Tnfrsf1b,Traf2,Birc2,Casp8,Cycs,Casp3,Mdm2,Casp2 |
| 4.165e-08 | -16.99 | HOELZEL_NF1_TARGETS_UP | MSigDB lists | HOELZEL_NF1_TARGETS_UP | 126 | 30 | 15632 | 1249 |
Ifi205,Ifi209,Plekha5,Ifi213,Dusp4,Acvrl1,Arhgap26,Ifi214,Upp1,Fas,Ifi207,Clcn5,Rnd3,Serpine1,Mndal,Plk2,Gdf15,Sesn3,Ifi203,Met,Phlda1,Ifi208,Ifi211,Ifi204,Traf3ip2,Endod1,Dram1,Dcbld2,Pcdh7,Osbpl3 |
| 4.275e-08 | -16.97 | GO_REGULATION_OF_VASCULATURE_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_VASCULATURE_DEVELOPMENT | 230 | 44 | 15632 | 1249 |
Tnfaip3,Notch1,Sphk1,Il1a,Hif1a,Lif,Pml,Hhex,Acvrl1,Il1b,Pf4,Vegfc,Thbs1,Cxcl10,Ptgs2,Zc3h12a,Hmox1,Ptger4,Rapgef2,Wars,Pdgfb,Pik3r6,Serpine1,Ppp1r15a,Ccl5,Pde3b,Cd34,Col4a2,Cx3cl1,Egr1,Il6,Ccr3,Ccl12,Flt1,Cx3cr1,Kdr,Sema4a,Adrb2,C3,Stat1,Itga5,Mtdh,Sirt1,Cysltr2 |
| 4.304e-08 | -16.96 | GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_DN | 169 | 36 | 15632 | 1249 |
Plau,Il15,Gbp2,Fabp3,Il6,Tlk2,Optn,Vcan,Acvr1,Dtnb,Cxcl1,Ccl4,Nfkb2,Tnfaip2,Il15ra,Acp2,Il1b,Cdkn1a,Ptges,Irf1,Ptgs2,Acsl1,Tlr2,Ube2l6,Inpp5b,Psme2,Scn1b,Zfp36,Htra1,Stat4,Bst1,Etv6,Slc4a7,Slc31a2,Ccl5,Marco |
| 4.382e-08 | -16.94 | GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | 184 | 38 | 15632 | 1249 |
Pde5a,Cers6,Kremen1,Arhgap26,Cd200r4,4932438A13Rik,Peli1,Slfn8,Tbc1d1,Dse,Usp53,Crbn,Gramd1a,Ifit1bl1,Daxx,Ifit1,Adar,Sgk3,Prdm1,Kctd12,Syne2,Rap1gap2,Rasgrp1,Parp12,Zfp36,Stxbp3,Ampd3,H2-Aa,Ppm1k,Lnpep,Ccl5,4930523C07Rik,Ifit1bl2,Epsti1,Slfn9,Rsbn1,Tmem229b,Acvr1b |
| 4.382e-08 | -16.94 | GSE360_DC_VS_MAC_L_DONOVANI_UP | MSigDB lists | GSE360_DC_VS_MAC_L_DONOVANI_UP | 184 | 38 | 15632 | 1249 |
Trp53i11,Cd83,Rbms2,Daxx,Relb,Angpt1,Mvp,Dnase1l3,Ch25h,Palld,Calcrl,Ccl22,Nlrp3,Ctsc,Casp3,Ly75,Rhoq,Gpr35,Scarf1,Dpy19l1,Nfkbia,Cst7,Ppp6r1,Rbbp8,Vcam1,Cflar,Adam19,Ppfibp2,Casp7,Pim2,Cd200,Kcna3,H2-Aa,Nmi,Alas1,Birc3,Txn1,Cd86 |
| 4.393e-08 | -16.94 | symbiont-containing vacuole | cellular component | GO:0020003 | 14 | 9 | 20747 | 1409 |
Gbp8,Iigp1,Gbp3,Pf4,Irgm2,Gbp2,Gbp2b,Gbp9,Gbp7 |
| 4.529e-08 | -16.91 | cellular protein metabolic process | biological process | GO:0044267 | 2960 | 272 | 20694 | 1406 |
St3gal5,Btg2,Mdm2,Mlkl,Extl2,Trib3,Mppe1,Tet2,Mapkapk2,Tmtc2,Il1b,Dtx2,Acp2,Pim3,Isg15,Ppp2r3a,Sla,Tlr3,Itgav,Ppm1l,Ppp2r5a,Ccnd1,Keap1,Cdk5r1,Prkce,Thbs1,Plk2,Cpeb4,Grk3,Ube2l6,Prdm9,Fbxo4,Ubr4,Ctsc,Bmp2,Kdm4a,Ccnd2,Acvr1b,Pgap2,Dusp1,Otud1,Sap30,Dusp8,Saa3,Lox,Plod3,Bnip3,Dusp4,Ppp1r15a,Psmb10,Plod2,Mark2,Kdm6b,Cnot4,Ube2e2,Kmt5a,Fut8,Ext1,Tmem67,Nck1,Rnf19a,Acvrl1,Serp1,Myd88,Met,Trim56,Denr,Casp8,Uba7,Ubash3b,Egr2,Setdb2,Dusp6,Kdr,Sik3,Gfpt1,Phlpp2,Rffl,Mdfic,Spsb1,Rnf139,Akt3,Ranbp2,Hat1,Sphk1,Bcor,Usp35,Jak2,Tnfaip3,Trib1,Il12rb1,Rictor,Tyk2,Ripk3,Peli1,Hck,Parp12,Src,Tpst1,Pdk3,Trim12c,Eif4g2,Map2k1,P4ha2,Lif,Pdgfb,Usp12,Flt1,Ube2e1,Ikbke,Psma6,Dpy19l1,Myc,Pdgfrb,Ptpn2,Ppp4r2,Rnf19b,Ptk2,Prag1,Kdm5b,Prkx,Dusp14,Ifih1,Dusp16,Birc2,Ccng2,Dnajb2,Nupr1,Il15,Parp8,Med21,Gtpbp2,Arrdc4,Tlr9,Psmb9,Birc3,Psmb8,Parp14,St3gal1,Scyl2,Mecp2,Usp31,Dcun1d3,Herc6,Eef1e1,Rnf34,Znrf3,Arid4a,Map3k8,Ppm1k,Trim12a,Stat5a,Hopx,Eif2ak2,Arel1,Arf4,Fam20c,Sirt1,Trim13,Axl,Usp18,Htr2b,Lyn,St3gal3,Osm,Parp11,Trim30a,Sde2,Cdyl,Dusp5,Mrpl52,Dusp2,Ppp2r2a,Atm,Mmd,Ksr1,Ankib1,Mgat1,Rnf31,Psmb6,Malt1,P4ha1,Parp3,Dusp28,Vrk2,Fgr,Map3k6,Igf1r,Larp1,Wars,Dr1,Uchl1,Jmjd6,Kat2b,Ccl5,Hk1,Bfar,Pml,Ccnj,Eya4,Ccl12,St3gal6,Pim2,Armc8,Parp10,Stat4,Rnf135,Syk,Pcgf5,Trim36,Mapkbp1,Plk3,Tnf,Irak2,Tiparp,Zc3h12a,Il18,Chmp4b,Mocs1,Znrf1,Vcpip1,Crbn,Plpp1,Usp53,Pim1,Tlr2,B3gnt5,Map4k4,Gcnt2,Dyrk2,Ccne1,Jarid2,Ptprj,Tlk2,Usp25,Nek6,Traf2,Mul1,Parp9,Ripk2,Irgm2,Stk40,Rnf14,Nos2,Dtx3l,Irak3,Irf4,Ep400,Zfp36,Mtmr14,Cop1,Morc3,Sgk3,Ccr3,Socs7,Trim21,Nsd3,Ube2f,Hdac1,Phlpp1,Rars,Klhl25,Pigv,S100a8,Ppp1r15b,Acvr1,Map2k4,Ptger4,Mmp13,Usp42,Egln3,Naa25 |
| 4.684e-08 | -16.88 | RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways | REACTOME pathways | R-MMU-168928 | 53 | 19 | 8608 | 757 |
Ikbkg,Irf2,Irf7,Nfkb1,Ddx58,Myd88,Ifna5,Tax1bp1,Ifna6,Ifna1,Irf1,Ifna4,Nfkbia,Nfkb2,Ifna2,Ikbke,Tnfaip3,Nfkbib,Ifnb1 |
| 4.721e-08 | -16.87 | GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_DN | MSigDB lists | GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_DN | 177 | 37 | 15632 | 1249 |
Slc2a6,Etv6,Stx11,Eef1e1,Mthfd1l,Map2k1,Lap3,Cacna1d,Ikbke,Abcc4,Nfil3,Parp3,Map3k8,Il2rg,D1Ertd622e,Irgm2,Stap1,Aebp2,Taf4b,Nr4a1,Nfkbia,Nlrc5,Casp1,Ppp1r14b,Arid5a,Tank,Birc2,Rhof,Ciita,Plagl2,Nfkbiz,Psme1,Plk3,Bcor,Icam1,Sell,Psmb10 |
| 4.759e-08 | -16.86 | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN | 155 | 34 | 15632 | 1249 |
Fabp3,Tulp3,Trim13,Upp1,Mcoln2,Slfn5,Daxx,Cd83,Pfkfb3,Cd40,Txnrd1,N4bp1,Src,Mllt6,Rin2,Ubtd2,Rai14,Lyn,Fpr1,Ptgs2,Dtx2,Actb,Acsl5,Casp4,Rrs1,Map4k4,Brd2,Rabgef1,Junb,Pou2f2,Dcp1a,Ampd3,Scn1b,Btg2 |
| 4.787e-08 | -16.85 | host cell part | cellular component | GO:0033643 | 22 | 11 | 20747 | 1409 |
Pf4,Gbp3,Axl,Iigp1,Sco1,Gbp8,Gbp7,Gbp9,Gbp2b,Gbp2,Irgm2 |
| 4.808e-08 | -16.85 | positive regulation of T-helper cell differentiation | biological process | GO:0045624 | 22 | 11 | 20694 | 1406 |
Nfkbiz,Il6,Irf1,Il18,Malt1,Il4ra,Nfkbid,Ripk2,Hlx,Tnfsf4,Nlrp3 |
| 4.810e-08 | -16.85 | SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP | MSigDB lists | SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP | 32 | 14 | 15632 | 1249 |
Ptges,Thbs1,Egr1,Hmox1,Socs3,Ier2,Stk40,Egr2,Phlda1,Srxn1,Slc2a1,Dusp6,Ccl12,Spsb1 |
| 4.833e-08 | -16.85 | AMIT_SERUM_RESPONSE_60_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_60_MCF10A | 52 | 18 | 15632 | 1249 |
Plk2,Ets2,Inhba,Tnc,Rcan1,Ptgs2,Trib1,Irs2,Map3k8,Ier2,Egr3,Ptger4,Ell2,Egr1,Zc3h12a,Dusp5,Klf7,Tnfaip3 |
| 4.984e-08 | -16.81 | positive regulation of stress-activated MAPK cascade | biological process | GO:0032874 | 172 | 33 | 20694 | 1406 |
Gadd45b,Il1rn,Il1b,Gadd45g,Mlkl,Fzd5,Zc3h12a,Nod1,Nod2,Tlr3,Sphk1,Sema4c,Tlr6,Edn1,Nox1,Fcgr2b,Map2k4,Bmp2,Rasgrp1,Tlr9,Map4k4,Met,Myd88,Ripk2,Mul1,Eif2ak2,Il1a,Mdfic,Mid1,Tnf,Mapkbp1,Syk,Traf2 |
| 4.998e-08 | -16.81 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | 653 | 92 | 15632 | 1249 |
Lif,Ddx58,Ifi213,Ttc39c,Dse,Slc2a1,Tank,Ifi205,Rbbp8,Eno1,Usp31,Dusp5,Scyl2,Ak4,Clic4,Gng12,Dcbld2,Igf2bp2,Glrx,Nampt,Mthfd1l,Plk2,Ascc3,Slc7a5,Nmi,Ifi208,Wars,Hk2,Rars,Phip,Xrn1,Rnd3,Plau,Rras2,Pnpt1,Rab32,Cenpe,Slc7a11,Tmod3,Denr,Ier3,Eif4g2,Psat1,Birc3,Lnpep,Ifit3,Casp4,Plscr1,Ifi203,Eef1e1,Ifih1,Etv5,Ifit2,Slc16a3,Txnrd1,Ifi209,Tnc,Ogfrl1,Trib3,Adora2b,Spire1,Gtpbp2,Mitd1,Irak2,Stip1,Cdyl,Gdf15,Tap2,Asns,Fas,Tpx2,Ifi214,Slc16a1,Ifi207,Slfn5,Atp11b,Trim36,Ppp1r14b,Tor1aip2,Vcan,Ifrd1,Ifi204,Ifit3b,Mthfd2,Rbms1,Gfpt1,Ldlr,Sema3c,Mndal,Ifi211,Ppp4r2,Xaf1 |
| 5.008e-08 | -16.81 | regulation of phagocytosis | biological process | GO:0050764 | 101 | 24 | 20694 | 1406 |
Fcgr2b,Ptprj,Fpr2,Siglece,Hck,Ccl2,Fcgr1,Cnn2,Tnf,Il2rg,Abr,Syk,Il1b,Ptk2,C3,Il15ra,Cd300lf,Tlr2,Il15,Nod2,Stap1,Itgav,Sphk1,Fgr |
| 5.008e-08 | -16.81 | regulation of reactive oxygen species biosynthetic process | biological process | GO:1903426 | 101 | 24 | 20694 | 1406 |
Il1b,Sirt1,Acp5,Zc3h12a,Cav1,Tlr2,Icam1,Klf2,Tlr6,Jak2,Il10,Cx3cr1,Ass1,Cd34,Stat3,Cflar,Tspo,Sod2,Tnf,Ptgs2,Klrk1,Atp2b4,Il6,Arg2 |
| 5.043e-08 | -16.80 | PID_PDGFRB_PATHWAY | MSigDB lists | PID_PDGFRB_PATHWAY | 127 | 30 | 15632 | 1249 |
Dock4,Ptpn2,Jun,Fos,Itgav,Pik3r5,Tagln,Src,Stat5a,Eif2ak2,Myc,Prkce,Stat3,Pla2g4a,Sphk1,Fgr,Nck1,Hck,Sla,Pik3r6,Map2k1,Pdgfrb,Pdgfb,Ksr1,Pik3cd,Lyn,Map2k4,Stat1,Ptprj,Jak2 |
| 5.048e-08 | -16.80 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_DN | 170 | 36 | 15632 | 1249 |
Slc39a14,Hivep3,Nfkbid,Stx6,Phlda1,Ifit3,Med21,Rrs1,Ttc9c,Mob3c,Keap1,Il1rn,Serpinb2,Ifit3b,Egr3,Cd200,Treml2,Irf4,Parp14,Gclm,Cish,Rab11fip1,Egr2,Ccdc86,Homer1,Rbbp8,Tnf,Srm,Cd38,Crim1,Prpf38a,Dusp14,Sdc4,Rtp4,Gmppb,Lif |
| 5.099e-08 | -16.79 | GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_UP | MSigDB lists | GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_UP | 185 | 38 | 15632 | 1249 |
H2-Aa,Inpp5b,Rhou,Ccl5,Hsd17b12,Cd86,Kitl,Clcn7,Ppfibp2,Pkp4,Dio2,Igf2bp2,C3,Ppa1,Mmp9,Ell2,Fam111a,Mthfd2,Serpinb9,Il2rg,Odc1,Cp,Ifi44,Spry2,Il18bp,Ccnd1,Cst7,Agrn,Dusp1,Spic,Tspan3,Ttc39c,Ahsa1,Zfp513,Evl,Nr1h3,Pttg1,Cd74 |
| 5.099e-08 | -16.79 | GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 185 | 38 | 15632 | 1249 |
Traf5,Tsku,Pml,Ccl22,Il1a,Pttg1,Upp1,Traf1,Irs2,Cish,Pnp2,Il6,Egr2,Ccnd1,Rsad2,P4ha2,Vcam1,Pcdh7,Plat,Kdr,Il15ra,Gfi1,Cmpk2,Frmd6,Dnajb2,Kpna3,Itga5,Rcn1,Rcan1,Cacnb3,Ak4,Csf1,Phlda1,Ccrl2,Mmp13,Cxcl2,Tuba4a,Cav1 |
| 5.099e-08 | -16.79 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN | 185 | 38 | 15632 | 1249 |
Ube2l6,Mmd,Pla2g7,Bst1,Tmem176a,Syne2,Rgl1,Txn1,Cav1,Lcp2,Il10,Kitl,Ralgds,Cd82,Ptger4,Hmox1,Ttc39b,Rab20,Abcb1a,Aebp2,Tra2a,Nfkbie,Cxcl14,Axl,Nfkbia,Parp8,Itgav,Mrpl52,Col4a2,1600014C10Rik,Clec4e,Fcgr1,Cdc42ep2,Myo10,Mapkapk2,Nr1h3,Dmxl2,P2ry14 |
| 5.173e-08 | -16.78 | GO_NEGATIVE_REGULATION_OF_CELL_ADHESION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_ADHESION | 208 | 41 | 15632 | 1249 |
Nfkbid,Spint2,H2-Eb1,Myadm,Cd274,Il10,Serpine1,Il1rn,Jak2,Gcnt2,Thbs1,Tnfsf4,Ptk2,Irf1,Tgfbi,Adrb2,Casp3,Tnc,Peli1,Mmp14,Acvrl1,Ifnb1,Pde5a,Spn,Src,Ass1,Swap70,Bcl6,Ptpn2,Bmp2,Pde3b,Cd164,Tnfrsf14,Notch1,Angpt1,Hlx,Ubash3b,Prnp,Cd74,Il4ra,Rnd1 |
| 5.338e-08 | -16.75 | leukocyte cell-cell adhesion | biological process | GO:0007159 | 48 | 16 | 20694 | 1406 |
Il1b,Sele,Cx3cr1,S100a8,Itgal,Spn,Itga4,Icam1,Tnf,Ccl5,Olr1,Tnip1,Sell,Vcam1,Itga5,Syk |
| 5.354e-08 | -16.74 | GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP | 163 | 35 | 15632 | 1249 |
Pml,Pgs1,Nxf1,Hif1a,Upp1,Adar,Tnfaip3,Pik3r5,Eif2ak2,Flt1,Oas3,Ifi44,Fchsd2,1110038F14Rik,Phlpp1,Herc6,Ifit3b,Snn,Cmpk2,Epsti1,Fmnl2,Tnfrsf1b,Rgl1,Rims3,Lap3,Vps54,Ifit3,Irf8,St3gal5,Ext1,Ksr1,Etv6,Oas2,Parp12,Wars |
| 5.354e-08 | -16.74 | GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_DN | MSigDB lists | GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_DN | 163 | 35 | 15632 | 1249 |
Itga4,Prdm1,Cd38,Atp2b4,Il15,Slamf7,Ttc39c,Ptpn2,Parp8,Cst7,Casp1,Pik3r5,Mlkl,Fcgr2b,Tnfsf8,Grina,Ttc39b,Ptger4,Ptprj,Ell2,Epsti1,Osbpl3,Rgs1,Adam19,Itgal,Hopx,Asns,Tnfsf14,Casp4,Snx10,Myadm,Ccl5,Tnfrsf1b,Smpdl3b,Il18rap |
| 5.369e-08 | -16.74 | eosinophil chemotaxis | biological process | GO:0048245 | 18 | 10 | 20694 | 1406 |
Ccl7,Ccr3,Ccl12,Ccl9,Ccl5,Cx3cl1,Ccl2,Ccl4,Ccl22,Ccl8 |
| 5.426e-08 | -16.73 | GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION | 1341 | 161 | 15632 | 1249 |
Nlrp3,Etv3,Trim13,Prnp,Lrp8,Egr1,Atf3,Gclc,Adar,Ciita,Hinfp,Tiparp,Jun,Psmd10,Nfkbia,Ezr,Nlrc5,Peli1,Myc,Edn1,Ikzf1,Irf1,Acvr1b,Stat1,Tnfsf4,Gfi1,Hcls1,Dr1,Ptch1,Irf8,Dach1,Birc3,Ifi203,Hat1,Sirt1,Timeless,Hif1a,Kdm4a,Pml,Irf2,Mxd1,Hhex,Nfkbil1,Mdfic,Relb,Daxx,Notch1,Bmp2,Ifi205,Rbbp8,Eno1,Birc2,Ifi213,Src,Ccnd1,Kdm5b,Mdm2,Setdb2,Pim1,Zc3h12a,Cd55,Zhx2,Igf2bp2,Thbs1,Nfxl1,Cmklr1,Junb,Jarid2,Txn1,Arid4a,Hap1,Nfkbid,Ifi208,Pdgfb,Btg2,Cdk5r1,Nr1h3,Ifi214,Bcor,Nck1,Rbl1,Ahr,Ifi207,Cd34,Ets2,Hmga1,Cited2,Nlrc4,Eif2ak2,Pcx,Ddx4,Trib1,Ifi204,Max,Cpeb4,Tlr9,Mtdh,Cdkn1a,Nfil3,H3f3b,Ccl4,Tax1bp1,Polr2g,Nos2,Mndal,Rel,Mov10,Cav1,Ahrr,Jdp2,Ednrb,Nfkb1,Etv6,Med13,Zfp36,Zeb1,Ifi211,Spen,Trim14,Trim21,Zfp281,Rnf139,Plk3,Parp10,Prdm1,Aim2,Tnfaip3,Irak3,Cd38,Pbx1,Bcl6,Zmynd15,Ifi209,Arid5a,Tnf,Prdx5,Mecp2,Hdac1,Aebp2,Itgb8,Stat3,Nr4a3,Arid5b,Trib3,Hmox1,Keap1,Il1b,Nfkb2,Irak2,Irf7,Map2k1,Serpine1,Fosb,Hopx,Ppp1r15a,Myadm,Ccl5,Gja1,Ccr1,Fzd1,Sap30 |
| 5.450e-08 | -16.73 | KIM_GLIS2_TARGETS_UP | MSigDB lists | KIM_GLIS2_TARGETS_UP | 94 | 25 | 15632 | 1249 |
Tgfbi,Irf1,Tlr2,Cxcl10,H2-Ab1,C3,Socs3,Pf4,Vcam1,Lad1,Casp4,Serpine1,Psmb8,Ltbp2,Ccl5,H2-Aa,Icam1,Cd74,Isg15,Cx3cl1,Col18a1,Psmb9,Ccl12,Cxcl14,Mmp14 |
| 5.450e-08 | -16.73 | GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 94 | 25 | 15632 | 1249 |
Rffl,Gclm,Acvr1,Itgav,Tnf,Cx3cr1,Src,Hspa1a,Traf2,Gclc,Rnf34,Tnfaip3,Fas,Cx3cl1,Phip,Il1a,Icam1,Serpine1,Casp8,Thbs1,Tnfsf10,Cflar,Pf4,Il1b,Hmox1 |
| 5.483e-08 | -16.72 | GO_RESPONSE_TO_INORGANIC_SUBSTANCE | MSigDB lists | GO_RESPONSE_TO_INORGANIC_SUBSTANCE | 452 | 70 | 15632 | 1249 |
Hp,Kdm6b,Ldha,Hmox1,Zc3h12a,Ptgs2,Nr4a3,Vcam1,Clic4,Lrp11,Thbs1,Il1b,Ptges,Keap1,Junb,Cd86,Ppp1r15a,Klf2,Fosb,Pdgfrb,Slc25a12,Slc30a4,Hif1a,Icam1,Il1a,Sphk1,Cd14,Hvcn1,Daxx,Tnfaip3,Klf6,Src,Dusp1,Traf2,Homer1,Casp3,Cp,Mdm2,Ccnd1,Mecp2,Hmgcs1,Tnfsf4,C3,S100a8,Nfkb1,Ppp1r15b,Cav1,Casp8,Ptch1,Sirt1,Il18rap,Fas,Col18a1,Prnp,Sdc1,Slc30a1,Prdx1,Tspo,Atp2b4,Olr1,Ass1,Sod2,Fos,Jun,Bnip3,Edn1,Pla2g4a,Il6,Il18bp,Nqo1 |
| 5.495e-08 | -16.72 | Viral myocarditis | KEGG pathways | mmu05416 | 85 | 25 | 7931 | 713 |
Cycs,Casp3,H2-T22,H2-Q4,H2-Q7,Sgcb,H2-T24,Cd55,H2-Ab1,Ccnd1,H2-Eb1,Icam1,Rac3,Cd40,Itgal,Eif4g2,H2-M2,Casp8,Cd86,H2-Q6,Cd80,H2-Aa,Cav1,Actb,H2-T10 |
| 5.510e-08 | -16.71 | GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN | MSigDB lists | GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN | 178 | 37 | 15632 | 1249 |
Plod3,Aoah,Itpr1,Mtus1,B4galt4,Igsf6,Gpr35,Ubtd2,Prdx5,Lrp8,Papss2,Atp11a,Sgms2,Gpc1,F10,Rnd3,Ppfibp1,Olr1,Rab3ip,Hdc,Slc7a2,Lmo4,Lcn2,Rnaset2a,Alas1,Tlr1,Pstpip2,Slc25a12,C3,Rnf19b,Sema4a,Mefv,Clec5a,Cflar,Tfec,Dio2,Rnaset2b |
| 5.510e-08 | -16.71 | GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_UP | MSigDB lists | GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_UP | 178 | 37 | 15632 | 1249 |
Bcl2a1a,Nfkb2,Clic4,Rap2c,Snn,H2-Ab1,Endod1,Trib3,Map3k8,Acsl1,Nr4a3,Btg2,Akt3,Usp12,Rapgef2,Stx11,Maff,Vasp,Cd69,Nampt,Tnfrsf1b,Gch1,Ppp1r15a,Sipa1l1,Cdc42ep2,Gbp2,Kmo,P2ry14,Fabp3,Phgdh,Tlk2,Bcl2a1d,Nr4a1,Bcl2a1b,Sod2,Arid5a,Rbbp8 |
| 5.510e-08 | -16.71 | GSE16266_CTRL_VS_LPS_STIM_MEF_UP | MSigDB lists | GSE16266_CTRL_VS_LPS_STIM_MEF_UP | 178 | 37 | 15632 | 1249 |
Slc7a5,Tlr1,Icosl,Stx6,Hivep3,Sh3bp4,Junb,Serpine1,Lcp2,Thbs1,Rgs1,Chd9,Siglece,Pmepa1,Hmox1,Ell2,Itga5,Ier3,Rffl,Stk40,Chst11,Nfkbie,Itgav,Nfkbia,Dusp1,Trim36,Morc3,Swap70,Gnb4,Olr1,Tle3,Tsku,Notch1,Nek6,Bcor,Plk3,Ier2 |
| 5.535e-08 | -16.71 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | 264 | 48 | 15632 | 1249 |
Ifih1,Socs1,Mcmbp,Cd14,Rbbp8,Dpy19l1,Minpp1,Ptgs2,Cxcl10,Fmnl2,Tfec,Kitl,Cd274,Ascc3,Fcgr4,Gja1,Inhba,Tnfsf15,Prnp,Papss2,Znrf3,Fas,Ddx60,Col4a2,Il15,Plau,Dock4,Cenpe,Nfkbia,Itgav,Ccl12,Vcan,Ctsc,Slc44a1,Igsf6,Rcn1,Etnk1,Dram1,Stat1,Cd200,Vrk2,Col27a1,Vezt,Cenpj,Pla2g7,Slc39a14,Xaf1,Akt3 |
| 5.615e-08 | -16.70 | GO_REGULATION_OF_AUTOPHAGY | MSigDB lists | GO_REGULATION_OF_AUTOPHAGY | 240 | 45 | 15632 | 1249 |
Tab2,Trim13,Kdm4a,Hif1a,Ifi214,Cdk5r1,Pikfyve,Chmp4b,Ifi207,Nod1,Tspo,Itpr1,Ifi209,Ifi205,Ifi213,Sqstm1,Casp1,Tlk2,Bnip3,Casp3,Ifi204,Mefv,Adrb2,Rab20,Mtdh,Larp1,Dram1,Pim2,Uchl1,Ripk2,Zc3h12a,Htr2b,Kdr,Fzd5,Plk2,Mndal,Atp6v1d,Atm,Sh3bp4,Sirt1,Met,Ifi203,Trim21,Ifi211,Ifi208 |
| 5.709e-08 | -16.68 | GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY | 58 | 19 | 15632 | 1249 |
Nlrp3,Nfkbil1,Tlr9,Parp10,Aim2,Zc3h12a,Tnfaip3,Gfi1,Irak3,Cmklr1,Irak2,Tax1bp1,Psmd10,Nfkbia,Nlrc5,Sirt1,Nfkbid,Trim21,Peli1 |
| 5.709e-08 | -16.68 | MODULE_254 | MSigDB lists | MODULE_254 | 58 | 19 | 15632 | 1249 |
Bnip3,Cd69,Bcl2a1d,Dusp6,Nfkb1,Bcl2a1b,Birc3,Birc2,Tnfsf14,Serpinb2,Tnfsf10,Bcl2a1a,Cflar,Il1b,Nupr1,Fas,Ier3,Ccnd2,Il1a |
| 5.887e-08 | -16.65 | GO_CELL_PROLIFERATION | MSigDB lists | GO_CELL_PROLIFERATION | 627 | 89 | 15632 | 1249 |
Tgfbi,Pim1,Uchl1,Larp1,Il15ra,Prkx,Plcl2,Igsf8,Ascc3,Cd86,Junb,Txn1,Ifi208,Ifna6,Il1a,Cd180,Hhex,Mcm10,Irf2,Mxd1,Malt1,Notch1,Bmp2,Cd40,Ifi205,Src,Ifi213,Acvrl1,Ccnd1,Azi2,Stat1,Ebi3,Tnfsf4,Ptch1,Tnfsf14,Il10,Dach1,Met,Ifi203,Egr1,Prdx1,Ifna1,Sbds,Il6,Pdpn,Abcb1a,Nr4a3,Hmox1,Ripk2,Kitl,Map2k1,Osm,Pdgfrb,Rab10,Ddit4,Psmb10,Cd74,Prdm1,Ifna2,Lipg,Ifi209,Txnrd1,Tnf,Tnfsf8,Stat3,Ifi204,Pim2,Fscn1,Mndal,Etv6,Isg20,Csf1,Zeb1,Fabp7,Ifi211,Tpx2,Ifi214,Irs2,Znrf3,Cdk5r1,Ifi207,Tspo,Il15,Cd34,Cited2,Syk,Ifna5,Ifnb1,Mmp14 |
| 5.924e-08 | -16.64 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | 186 | 38 | 15632 | 1249 |
Cd200,Fndc3a,Smox,Irak2,Tnip1,Snapc1,Gch1,Gja1,Plek,Gem,Serpine1,Tnfsf14,Etv6,Car13,Slc39a14,Inhba,Nek6,Cdkn2d,Nfkbiz,Malt1,Rnd1,Traf1,Upp1,Myo10,Hvcn1,Cst7,Rapgef5,Crbn,Plac8,Gpr18,Timp1,Carhsp1,Rab11fip1,Stard5,Rhoq,Cpd,Gadd45g,Mdm2 |
| 5.924e-08 | -16.64 | GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP | MSigDB lists | GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP | 186 | 38 | 15632 | 1249 |
Acvr1b,Nr4a3,Rcsd1,Notch2,Tmem123,Cep350,Psd4,Dusp6,Snx2,Kctd12,Rasgrp1,Tlr1,Rab19,Spata13,Cd74,Dtx3l,Irf2,Rnf139,Crim1,Rab3ip,Crlf3,Nod1,Traf5,1600014C10Rik,Itpr1,Psmb9,Cd40,Tpst1,Klf3,Hivep2,Morc3,Rapgef5,Arhgap26,Triobp,Tapbp,Abcb1a,Bbx,Pde1b |
| 5.924e-08 | -16.64 | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_DN | 186 | 38 | 15632 | 1249 |
Epsti1,Rnaset2b,Socs3,Sema4a,Frmd4a,Nsmaf,Lyn,Rcn1,Plscr1,Kctd12,Snx2,Tnfrsf1b,Slc4a7,Mthfd1l,Plekha2,Rnaset2a,Fzd5,Asns,Ube2f,Myd88,Traf5,Ahr,Psme1,Aim2,Gbp3,Rnf135,Slco3a1,Rab19,Myc,Abcb1a,Spry2,Ctsc,Arhgap26,Rab32,Plac8,Dpy19l1,Cx3cr1,Trip10 |
| 5.924e-08 | -16.64 | GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_CD4_SP_THYMOCYTE_DN | 186 | 38 | 15632 | 1249 |
Rhof,Birc2,Dock4,Oas3,Dusp1,Ifnar1,Rnf114,Mllt6,Parp9,Triobp,Tnfsf8,Setdb2,Stat2,Zfp281,Etv3,Zfp513,Slc28a2,Relb,Tap1,Crlf3,Myd88,Bfar,Daam1,Abtb2,Jarid2,Akt3,Trim26,Irf1,Arid5b,Herc6,Parp3,Slc37a3,Sp110,Zhx2,Gsta3,Jak2,Gtpbp2,Tnip1 |
| 5.934e-08 | -16.64 | MODULE_169 | MSigDB lists | MODULE_169 | 88 | 24 | 15632 | 1249 |
Ccl5,Psmb8,Txn1,Cd86,Rgs1,Ccl4,Bcl2a1a,Prkar2b,Abcc1,Il15ra,Asb13,Ier3,Dusp2,Bcl2a1d,Bcl2a1b,Dhrs9,Bcl6,Fos,Crlf3,Hck,Ahr,Ripk3,Itga4,Isg15 |
| 5.950e-08 | -16.64 | MODULE_47 | MSigDB lists | MODULE_47 | 209 | 41 | 15632 | 1249 |
Cd34,Plau,Pfkfb3,Col4a2,Gng11,Palld,Col18a1,Plagl1,Hif1a,Tnc,Pdpn,Il6,Vcan,C1ra,Cnn2,Phldb1,Tagln,Jun,Tcf4,Thbs1,Plaur,Cdkn1a,Pmepa1,Filip1l,Tgfbi,Lox,Fpr1,Zeb1,Cnn3,Htra1,Bst1,Mmd,Inhba,Sh3bp4,Egln3,P4ha1,Ltbp2,Gja1,Sema3c,Pdgfrb,Serpine1 |
| 6.050e-08 | -16.62 | positive regulation of epithelial cell proliferation | biological process | GO:0050679 | 199 | 36 | 20694 | 1406 |
Itga4,Myc,Sirt1,Akt3,Notch1,Hmga2,Ccr3,Kdm5b,Itpr1,Htr2b,Rictor,Nod2,Tnfaip3,Cav1,Notch2,Hmox1,Nr4a3,Ccl5,Ccnd1,Ccl2,Stat3,Acvrl1,Egr3,Il10,Adora2b,Bmp2,Nr4a1,Vegfc,Pdgfb,Il6,Htra1,Kdr,Ccnd2,Cflar,Stat5a,Jun |
| 6.091e-08 | -16.61 | PID_P53_DOWNSTREAM_PATHWAY | MSigDB lists | PID_P53_DOWNSTREAM_PATHWAY | 128 | 30 | 15632 | 1249 |
Mdm2,Vcan,Bcl2a1d,Dusp1,Bcl2a1b,Casp1,Nlrc4,Bcl6,Jun,Apaf1,Tap1,Prdm1,Fas,Atf3,Plk3,Col18a1,Lif,Pml,Cx3cl1,Btg2,Ddit4,Met,Map4k4,Gdf15,Cav1,Serpine1,Bcl2a1a,Cd82,Cdkn1a,Dusp5 |
| 6.103e-08 | -16.61 | REACTOME_NOD1_2_SIGNALING_PATHWAY | MSigDB lists | REACTOME_NOD1_2_SIGNALING_PATHWAY | 28 | 13 | 15632 | 1249 |
Ripk2,Tab2,Irak2,Nod1,Tnfaip3,Casp1,Ikbkg,Birc3,Casp8,Birc2,Casp4,Casp2,Nod2 |
| 6.112e-08 | -16.61 | regulation of growth | biological process | GO:0040008 | 733 | 89 | 20694 | 1406 |
Sertad3,Cdkn1a,Pml,Acvrl1,Serp1,Myd88,Ikzf1,Dcbld2,Tnf,Daxx,Dusp6,Sh3bp4,Cited2,Agrn,Il12b,C3,Bcl6,Gdf15,Notch2,Cdkn2d,Phip,Sema4a,Cd38,Acvr1b,Hif1a,Cyfip1,Hmga2,Ppp2r3a,Pttg1,Irf8,Sirt1,Ahr,Cdk5r1,Psmd10,Crlf3,Osm,Gja1,Ptch1,Sqstm1,Dbnl,Il10,Rab21,Ezr,Slc9a1,Adrb2,Hopx,Socs1,Pnpt1,Stat5a,Socs3,Mecp2,Dcun1d3,Ptger4,Ogfr,Sav1,Ptk2,Mmp14,Vps54,Csf1,Serpine1,Dnajb2,Nod2,Edn1,Sema4c,Cish,Socs7,Ifrd1,Ptprj,Eif4g2,4932438A13Rik,Jarid2,Stat3,Gng4,Bcl2l11,Sema3c,Nr3c1,Mul1,Hlx,Mndal,Notch1,Trip10,Plac8,Tomm70a,Pim1,Tlr2,Osgin2,Inhba,Sphk1,Crkl |
| 6.127e-08 | -16.61 | metabolic process | biological process | GO:0008152 | 7286 | 588 | 20694 | 1406 |
Dnase1l3,Optn,Hk3,Mthfd1l,Swap70,Mcm6,Ranbp2,Crkl,Hat1,Usp35,Bcor,Stat1,Prdx5,Il12rb1,Cycs,Trib1,Ripk3,Mcm10,Adar,Tnks1bp1,Smpdl3b,Parp12,Stat3,Hck,Src,Itpkc,Rbms1,Tpst1,4932438A13Rik,Tapbp,Ampd3,Pdgfb,Ak4,P4ha2,Ero1l,Ptafr,Phyh,Ikbke,Fam111a,Pde5a,Myc,Rsbn1,Dcp1a,Plagl2,Rnf19b,Ppp4r2,Kmo,Ifih1,Pde1b,Dusp16,Ppa1,Birc2,Aff1,Tlr9,Parp8,Pgs1,Parp14,Ezr,Dio2,Scyl2,Glrx,Ddit4,St3gal1,Dcun1d3,Mecp2,Usp31,Znrf3,Trim12a,Hopx,Ell2,Extl2,Slc7a2,Mdm2,Dram1,Mppe1,Mapkapk2,Pttg1,Hmga2,Ppp2r3a,Tmtc2,Dtx2,Hk2,Alas1,Il4i1,Itgav,Cemip2,Casp3,Pcx,Nr4a3,Ccnd1,Slfn8,Grk3,Prdm9,Thbs1,Plk2,Trem1,Fbxo4,Prnp,Ubr4,Ddhd1,Samhd1,Ctsc,Kdm4a,Hif1a,Ccnd2,Pgm1,Cflar,Sap30,Ciita,Dusp8,Dusp4,Mmp25,Plod3,Ppp1r15a,Plod2,Mark2,Cnot4,Il1rn,Txn1,Kdm6b,Cgas,Fut8,Ube2e2,Kmt5a,Hmgcs1,Vcam1,Ext1,Zhx2,Calcrl,Egr1,Me1,Myd88,Serp1,Psat1,Rcl1,Met,Irgm1,Gch1,Ubash3b,Phlpp2,Gfpt1,Plaat3,Kdr,Setdb2,Egr2,Magohb,Mdfic,Tiparp,Irak2,Vcpip1,Znrf1,Lipe,Gsta3,Plpp1,Tlr2,Hmox1,Pim1,Trmt1l,Map4k4,Gcnt2,Dyrk2,Icosl,Asns,Cmpk2,Aoah,Ass1,Ptprj,Tlk2,Nmi,1600014C10Rik,Htra1,Mcmbp,Irgm2,Sesn3,Parp9,Endod1,Smc5,Nos2,Gadd45g,Irak3,Zfp36,Cop1,Morc3,Dhrs9,Enpp4,Itgb8,Clic5,Tent2,Xrn1,Trim21,Pla2g7,Carmil1,Sgms2,B4galt4,Yju2,Hdac1,Plau,Adam19,Gbgt1,S100a8,Tnfsf4,Hinfp,Acvr1,Ptger4,Mov10,Hdc,Tgs1,Mmp13,Egln3,Arf4,Fam20c,Irf8,Axl,Acsl5,Txnrd1,Trim13,Hhex,Helz2,Usp18,Lmo4,Ptch1,Htr2b,Tnip1,Slc7a11,Chst11,Lyn,C1rl,Parp11,Ahr,Timeless,Degs2,Sat1,Cdyl,Isg20,Dusp2,Aldh1b1,Atm,Tent4a,Upp1,Acsl1,Higd1a,Olr1,Fos,Rnaset2b,Ahrr,Ankib1,Minpp1,Psmb6,Oas2,Rnf31,Junb,Prpf4,Malt1,C3,Cd74,Dusp28,Igf1r,Larp1,Psip1,Vrk2,Fgr,Map3k6,Wars,Nox1,Nod1,Cdkn2d,Srm,Ccl5,Prdm1,Bfar,Noct,Col4a2,Pml,Ciapin1,Pim2,Zc3h12c,Ago3,Eya4,Ccnj,Syk,Stat4,Smox,Agpat4,Trim36,Sod2,Rnf139,Spsb1,Akt3,Pdss1,Tcea1,Sphk1,Tlr6,Jak2,Rictor,Ptges,Pgk1,Inhba,Tnfaip3,Irf7,Tyk2,Nr3c1,Nxf1,Phlda1,Peli1,Odc1,Map2k1,Pdk3,Trim12c,Eif4g2,Lif,Slc25a25,Arg2,Oas1a,Usp12,Flt1,Tnfsf15,Ube2e1,Psma6,Dpy19l1,Gpc1,Wdr43,Pdgfrb,Ptpn2,Gda,Ptk2,Slc25a22,Nr1h3,Gbe1,Prag1,Kdm5b,Prkx,Ch25h,Fosb,Dusp14,Dgkh,Rhoq,Snapc1,Zc3h7a,Dnajb2,Ccng2,Gsr,Il15,Nupr1,Arrdc4,Dcp2,Gtpbp2,Adrb2,Psmb9,Med21,Batf,Cept1,Birc3,Psmb8,Herc6,Eef1e1,Socs3,Arid4a,Inpp1,Rnf34,Kif5c,Apobec3,Slfn9,Ascc3,Stat5a,Map3k8,Ppm1k,Pnpt1,Eif2ak2,Pdpn,Socs1,Hsd17b12,Btg2,St3gal5,Ttc39b,Mlkl,Acp5,Tet2,Polr2g,Trib3,Pim3,Isg15,Sla,Acp2,Il1b,Tlr3,Plat,Ifnar1,Ppm1l,Ppp2r5a,Keap1,Prkce,Cdk5r1,Ube2l6,Cpeb4,Plek,Dck,Casp2,Bmp2,Acvr1b,Pgap2,Dusp1,Otud1,Mcm9,Phgdh,Lox,Saa3,Bnip3,Tha1,Psmb10,Tra2a,Agrn,Tmem67,Mtfr2,Srgn,Rnf19a,Mthfd2,Fnbp1l,Nck1,Acvrl1,Trim56,Rbbp8,Nampt,Denr,Pikfyve,Casp8,Eno2,Uba7,Gys1,Pla2g4a,Cp,Srxn1,Sik3,Dusp6,Inpp5b,Rffl,Fgl2,Il18,Mdn1,Zc3h12a,Mocs1,Chmp4b,Crbn,Top3a,Sbds,Usp53,Tut7,B3gnt5,Casp4,Hivep2,Hsd17b7,Casp1,Jarid2,Ccne1,Hap1,Rrs1,Rnaset2a,Dgka,Idi1,Ldlr,Smg7,Nek6,Usp25,Mthfr,Traf2,Stk40,Lrp4,Mul1,Ripk2,Mvp,Pfkfb3,Gpd2,Rnf14,Svbp,Dtx3l,Gclm,Usb1,Ep400,Lnpep,Irf4,Sgk3,Mmp14,Mtmr14,C1ra,Cers6,Ccr3,Casp7,Med13,Prkar2b,Trip13,Socs7,Cish,Edn1,Hmga1,Papss2,Rubcnl,Fas,Ube2f,Nsd3,Esd,Rars,Phlpp1,Pigv,Gk,Klhl25,Asf1a,Il10,Cnp,Map2k4,Gmppb,Ppp1r15b,Plpp3,Usp42,Hspa1a,Tspo,Naa25,Plcl2,Arel1,Ctu1,Mmp9,Sirt1,Sqstm1,Riox2,Acod1,St3gal3,Osm,Cav1,Trim30a,Adhfe1,Pbx1,Pik3cd,Dusp5,Sde2,Ldha,Plscr1,F10,Tpi1,Ppp2r2a,Marf1,Mrpl52,Ddx4,Nfil3,Oasl2,Ksr1,Mmd,Mgat1,Ptgs2,Arid5b,Slc25a12,Lipg,P4ha1,Nqo1,Parp3,Gclc,Nt5c3,Lpcat2,Adgb,Pfkl,Nlgn2,Dr1,Jmjd6,Kat2b,Uchl1,Slc16a1,Hk1,Dse,Prdx1,Etnk1,Angpt1,Prpf38a,Atf3,Armc8,Acpp,Asah2,St3gal6,Parp10,Taf4b,Cpd,Ccl12,Caml,Selenow,Rnf135,Tcf4,Jun,Pcgf5,Lap3,Mapkbp1,Tnf,Plk3 |
| 6.282e-08 | -16.58 | GO_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | 64 | 20 | 15632 | 1249 |
Il12rb1,Rasgrp1,Fzd5,Irf8,H2-Q6,Tnf,Pde4b,H2-Q4,Ifnar1,Il1b,Il27,Cd14,Il18,Il12b,Tlr3,Tlr9,Ebi3,Tnfsf4,H2-Q7,Ripk2 |
| 6.285e-08 | -16.58 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP | 194 | 39 | 15632 | 1249 |
Dusp5,Casp7,Rnf19b,Asb13,4930453N24Rik,Adam19,Cmpk2,Cdkn1a,Stip1,Casp8,Irf7,Cnp,Tap2,Rel,Tlr1,Antxr1,Hat1,Uba7,Hivep3,Pml,Irf2,Rars,Il4ra,Arrdc4,Trim12c,Upp1,Fpr2,Ddx58,Slfn5,Tap1,Chmp4b,Cst7,Stat5a,Nlrc5,Eif2ak2,1110038F14Rik,Tapbp,Dhx58,Samd9l |
| 6.293e-08 | -16.58 | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP | 164 | 35 | 15632 | 1249 |
Eif2ak2,Ifit1bl1,Cenpe,Casp1,Gpsm2,Ifi44,Cd200r4,Fgl2,Optn,Mlkl,Phactr4,Rsad2,Aim2,Nkiras1,Pttg1,Rtp4,Ifih1,Tpx2,Cd38,Hck,Ifit1bl2,Il10,Plk2,Casp8,Plod2,Casp4,Srxn1,Isg20,Plscr1,Xaf1,Dram1,Tnfsf4,Osgin2,Cmklr1,Gfpt1 |
| 6.293e-08 | -16.58 | GSE18281_MEDULLARY_THYMOCYTE_VS_WHOLE_MEDULLA_THYMUS_DN | MSigDB lists | GSE18281_MEDULLARY_THYMOCYTE_VS_WHOLE_MEDULLA_THYMUS_DN | 164 | 35 | 15632 | 1249 |
Mndal,Cd274,Ltbp2,Ccr1,Ifi203,Stoml1,Nmi,Ifi208,Ifi211,Ifi204,Oasl1,Ppa1,Herc6,Ppp2r2a,Fmnl2,Tank,Ifi205,Ifi209,Znfx1,Ifi213,Spn,Dhx58,Sat1,Parp14,Rtp4,Arl4a,Ifi214,Pttg1,Ddx58,Stat2,Rnf139,Usp25,Rars,Ifi207,Adar |
| 6.412e-08 | -16.56 | regulation of myeloid leukocyte differentiation | biological process | GO:0002761 | 125 | 27 | 20694 | 1406 |
Fos,Stat5a,Kitl,Jun,Ccl3,Tnf,Tmem178,Lif,Ubash3b,Ccr1,Casp8,Hcls1,Pf4,Pilrb1,Gpr68,Ikzf1,Ifnb1,Trib1,Notch2,Lyn,Ccl5,Csf1,Cd74,Clec2d,Il12b,Myc,Ptpn2 |
| 6.417e-08 | -16.56 | positive regulation of protein complex assembly | biological process | GO:0031334 | 217 | 38 | 20694 | 1406 |
Tlr6,Wars,Cav1,Carmil1,Rictor,Mpp7,Ahr,Prkce,Spire1,Fas,Icam1,Fscn1,Palld,Gda,Rac3,Rhoc,Cyfip1,Mecp2,Atm,Syk,G3bp2,P2ry12,Fchsd2,Vasp,Tnf,Aim2,Piezo1,Nck1,Evl,Whamm,Src,Ikzf1,Cdc42ep4,Met,Cdc42ep2,Bcl2l11,Plek,Csf3 |
| 6.421e-08 | -16.56 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_DN | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_DN | 179 | 37 | 15632 | 1249 |
Ubash3b,Cd180,Etv3,Ccl22,Rab19,Intu,Papss2,Sav1,Nod1,Pfkfb3,Vcpip1,Tnfaip3,Tap1,Nlrc5,Swap70,Rbbp8,Hmga1,Ccnd1,Mid1,Gsr,B3gnt5,Acvr1b,Cacnb3,Spata5l1,Fam111a,Inpp1,Tmem123,Fam20c,Lacc1,Abcc1,Plekhg1,Slc7a2,Ociad1,Cnn3,Alas1,Ccdc25,Stat4 |
| 6.447e-08 | -16.56 | GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | MSigDB lists | GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 436 | 68 | 15632 | 1249 |
Ifi205,Slc2a1,Ifi209,Ifi213,Src,Axl,Ccnd1,Mdm2,Cp,Slc39a4,Tnc,Sphk1,Icam1,Upp1,Mthfr,Apaf1,Lipg,Asns,Ppp1r15a,Ccl5,Fzd1,Ifi208,Wdr59,Cxcl10,Pim1,Adora2b,Ptgs2,Zc3h12a,Ldha,Hmox1,Il1b,Lrp11,Vcam1,Jun,Fos,Ccl12,Ass1,Eif2ak2,Gsdmd,Nqo1,Il6,Pla2g4a,Ifi214,Cdkn2d,Atf3,Ifi207,Tspo,Slc16a1,Il15,Slc25a25,Mndal,Cav1,Ccne1,Clic5,Ifi203,Hat1,Sirt1,Zfp36,Ifi211,Adrb2,Lyn,Acsl1,Ifi204,Socs3,Max,Cpeb4,Hmgcs1,Cdkn1a |
| 6.781e-08 | -16.51 | negative regulation of leukocyte proliferation | biological process | GO:0070664 | 88 | 22 | 20694 | 1406 |
Arg2,Casp3,H2-Aa,Cd80,Atm,Slfn1,Tarm1,Tnfrsf14,Lyn,Peli1,H2-Ab1,Prnp,Spn,Prdm1,Pde5a,Cd274,Sdc4,Fcgr2b,Cd86,Ccl12,Il10,Lgals9 |
| 6.873e-08 | -16.49 | GSE36826_WT_VS_IL1R_KO_SKIN_UP | MSigDB lists | GSE36826_WT_VS_IL1R_KO_SKIN_UP | 187 | 38 | 15632 | 1249 |
Pdgfc,Ahr,Irs2,Nr1h3,Lrch3,Abr,Nupr1,Mdm2,Mecp2,Gadd45g,Dtnb,Cebpd,Ccng2,Sat1,Top3a,Tcf4,Aoah,Abcc5,Dhrs9,Slc7a11,Rnaset2b,Dnajb2,Htr2b,Notch2,Tax1bp1,Slc29a3,Tnfaip2,Pik3cd,Sema4a,Rab20,H2-Ab1,Dyrk2,Caml,H2-Aa,Cd86,Rnaset2a,Cep350,Plekha2 |
| 6.873e-08 | -16.49 | GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN | MSigDB lists | GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN | 187 | 38 | 15632 | 1249 |
Ociad1,Caml,St3gal5,Plscr1,Kctd12,Nfkb1,Ccl5,Bcl2a1a,Phyh,Odc1,Rcn1,Ttc39b,Minpp1,Rhoq,Slc44a1,Fgl2,Cox17,Rsad2,Bcl2a1d,Cpd,Plac8,Itgav,Bcl2a1b,Bcl2l11,Cst7,Casp1,Cyfip1,Psmd10,Tcf4,Traf5,Prpf38a,Mdfic,Rars,Mcoln2,Cyth3,Ciapin1,St3gal6,Gbe1 |
| 6.873e-08 | -16.49 | GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_UP | MSigDB lists | GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_UP | 187 | 38 | 15632 | 1249 |
Tapbp,Rin2,Rhoq,Gclm,Eno1,Swap70,Lipe,Spsb1,Eif2ak2,Tap1,Gpc1,Prdx1,Usp18,Tpi1,Hhex,Evl,Psme1,Procr,Caml,Nos2,Mov10,Rnaset2a,Tor3a,Tcea1,Lrrc8c,Gsta3,Rnaset2b,Esd,Pfkl,Polr2g,Kif3c,Mthfd2,Irf1,Cacnb3,Stat1,Hmox1,Gng4,Uchl1 |
| 6.873e-08 | -16.49 | GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_DN | 187 | 38 | 15632 | 1249 |
Myo10,Gbp2,Prpf38a,Sdc4,F10,Tal2,Cd80,Upp1,Socs1,Gbe1,Nr1h3,Nck1,Mapkapk2,Edn1,Tbc1d1,Rffl,Aoah,Parp8,Gramd1a,Pkp4,Lhx2,Rcl1,Rnaset2b,Gsta3,Slfn3,Gfpt1,Il2rg,Endod1,Kif5c,Rnf19a,Bcl9,Srxn1,Gbgt1,Plscr1,Slfn4,Rnaset2a,Slc4a7,Jdp2 |
| 6.912e-08 | -16.49 | GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | 172 | 36 | 15632 | 1249 |
Aftph,Cish,Carhsp1,Cycs,Stat3,Irgq,Bcl2a1d,Rbpms,Bcl2a1b,Dnaja1,Gpr18,Arid5a,Myd88,Gbp2,Tle3,Bcor,Cdkn2d,Malt1,Il4ra,Il1a,Icam1,Prnp,Rasgrp1,Rap1gap2,Stat4,Lmo4,Klf2,Tnfsf14,Bcl2a1a,Pgk1,Ap3m2,Kdm6b,Endod1,Hp,Pim1,Tgfbi |
| 7.027e-08 | -16.47 | GO_MONOCYTE_DIFFERENTIATION | MSigDB lists | GO_MONOCYTE_DIFFERENTIATION | 24 | 12 | 15632 | 1249 |
Ifi213,Jun,Ifi205,Mndal,Ifi209,Pde1b,Ifi208,Ifi211,Ifi203,Ifi214,Ifi204,Ifi207 |
| 7.109e-08 | -16.46 | 2-5-oligoadenylate_synth_CS | interpro domains | IPR006117 | 8 | 7 | 19984 | 1430 |
Oas1g,Oas2,Oas1a,Oas1b,Oasl2,Oasl1,Oas3 |
| 7.279e-08 | -16.44 | HIF-1 signaling pathway | KEGG pathways | mmu04066 | 104 | 28 | 7931 | 713 |
Nfkb1,Eno1,Angpt1,Timp1,Nos2,Akt3,Hk2,Pik3cd,Stat3,Hmox1,Edn1,Slc2a1,Serpine1,Ldha,Igf1r,Flt1,Cdkn1a,Hif1a,Hk1,Egln3,Pgk1,Pfkl,Hk3,Map2k1,Nox1,Pfkfb3,Il6,Eno2 |
| 7.298e-08 | -16.43 | positive regulation of tyrosine phosphorylation of STAT protein | biological process | GO:0042531 | 55 | 17 | 20694 | 1406 |
Tnf,Ccl5,Il15,Clcf1,Lyn,Parp9,Osm,Jak2,Il6,Ptger4,Cd40,Lif,Hcls1,Il12b,Parp14,Il18,Hdac1 |
| 7.305e-08 | -16.43 | GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_UP | MSigDB lists | GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_UP | 136 | 31 | 15632 | 1249 |
Cflar,Mppe1,Ifit3b,Adrb2,Cd55,Srxn1,Ifit3,Hopx,Cd86,Gem,Ttc9c,Ifit1bl2,Ccl5,Cd38,Ncoa7,Dusp14,Mdfic,Traf5,Ddx58,Ddx60,Samd9l,Hspa2,Rsad2,Fcgr2b,Rab21,Ggct,Stap1,Ifi44,Homer1,Ifit1bl1,Ccl12 |
| 7.319e-08 | -16.43 | transferase activity | molecular function | GO:0016740 | 2228 | 217 | 20217 | 1400 |
Pgs1,Fgr,Parp11,Hk1,Nat2,Jak2,Gfpt1,Map2k4,Plaat3,Met,Cd38,Dgkh,Dtx3l,Parp9,Tent2,Hck,Cdk5r1,Mark2,Cdkn1a,Pim2,Mapkapk2,Psat1,Prkx,Pdgfrb,Ripk3,Ciapin1,Syk,Eif2ak2,Kmt5a,Itpkc,Gcnt2,Cmpk2,St3gal1,Traf2,Grk3,Ccnd1,Trib1,Bfar,Tent4a,Cdyl,Pim3,Ptges,Pigv,Oasl1,B4galt4,Pdss1,Ube2e2,Prdm9,Med21,Cnot4,Extl2,Ccnj,Ube2f,Papss2,Trim21,Ccnd2,Hmgcs1,Parp14,Lpcat2,Dpy19l1,Gys1,Sgms2,Tpst1,Pdk3,Map4k4,Uba7,Pim1,Gmppb,Sphk1,Stk40,Fbxo4,Flt1,Trim12c,Setdb2,Irak2,Oasl2,Rnf34,Acvr1,Naa25,Sat1,Ranbp2,Akt3,Tgs1,Ube2e1,Scyl2,Trim56,Pfkfb3,Vrk2,Oas1a,Trmt1l,Dtx2,Polr2g,Ifnb1,Etnk1,Rnf139,Rabgef1,Rnf14,Chst11,Axl,Gbgt1,Hat1,Dck,Fut8,Mdm2,Trim36,Pik3cd,St3gal6,Prdm1,Atm,Rnf145,Acvr1b,Trim13,Zc3hav1,Sgk3,Cop1,Ust,Mid1,Oas1b,Fam20c,Igf1r,Sla,Gk,Rnf135,Src,B3gnt5,Trim12a,Ksr1,Oas3,Rnf31,Pikfyve,St3gal5,Dyrk2,Ptk2,Gbe1,Ext1,Egr2,Trim26,Plk2,Sik3,Cers6,Dgka,Nrp2,Lyn,Prkce,Rnf19b,Gsta3,Rnf114,Bcor,Pik3r6,Alas1,Pnp2,Ccng2,Kat2b,Map2k1,Parp8,Hk3,Map3k8,Hk2,Mgat1,Ccl5,Nt5c3,Malt1,Mlkl,Nek6,Pfkl,Parp12,Parp3,Cept1,Acvrl1,Nampt,Ikbke,Map3k6,St3gal3,Prag1,Ankib1,Bst1,Rnf24,Plk3,Pgk1,Plod3,Tiparp,Agpat4,Ciita,Birc3,Mul1,Ube2l6,Herc6,Znrf1,Birc2,Irak3,Ubr4,Ak4,Peli1,Upp1,Parp10,Oas1g,Tnfaip3,Pnpt1,Tut7,Ctu1,Rnf19a,Tlk2,Mmd,Trib3,Znrf3,Ccne1,Kdr,Oas2,Tyk2,Ripk2,Rffl,Nsd3,Trim30a,Tmtc2,Cgas,Arel1,Srm |
| 7.340e-08 | -16.43 | GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 129 | 30 | 15632 | 1249 |
Tlr3,Ptger4,Pik3cd,Lyn,Il12b,Sema4a,Nr4a3,Clec4d,Notch2,Plcl2,Cd86,Itgal,Ifna6,Stxbp3,Rasgrp1,Icam1,Cd180,Ifna1,Batf,Clec4e,Relb,Ifna2,Cx3cr1,Syk,Swap70,Irf4,Il6,Prkce,Ifnb1,Ifna5 |
| 7.385e-08 | -16.42 | GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_DN | MSigDB lists | GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_DN | 165 | 35 | 15632 | 1249 |
Sav1,Tnfrsf14,Rab3ip,Ahr,Slc28a2,Slc30a4,Csrnp1,Egr1,Socs1,Gbp3,Papss2,Spry2,Egr2,Errfi1,Dusp4,Nr4a1,Nfkbia,Ppp1r14b,Slc7a11,Bcl2l11,Rgs14,Ets2,Ralgds,Ppfibp2,Epsti1,Pmepa1,Arl5c,Itpkc,Socs3,Cacnb3,Nr4a3,Nfkbid,Spint2,Maff,Dusp6 |
| 7.385e-08 | -16.42 | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_DN | MSigDB lists | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_DN | 165 | 35 | 15632 | 1249 |
Ttc39c,Tspan3,Swap70,Plac8,Ehd1,Tnf,Itgav,Fgl2,Nfkbie,Gpr68,Cpd,Tmem171,Cish,Traf1,Nek6,Apaf1,Cd38,Atp2b4,Irak3,Cd86,Asns,Zc3h12c,Plod2,Ccr1,Dcun1d3,Isg20,Trib1,Kcna3,Grina,Fndc3a,Cdkn1a,Glrx,Osbpl3,Znrf1,Tnfsf10 |
| 7.472e-08 | -16.41 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP | 180 | 37 | 15632 | 1249 |
Irf8,Cd86,Gem,Jarid2,Plek,Myadm,Sesn3,Il18rap,H2-Aa,Ddx4,Il18,Acsl1,Lyn,Ebi3,Parp3,Rgs1,Slc29a3,Cd300lf,Gcnt2,D16Ertd472e,Bcl6,Parp8,Gramd1a,Ccnd1,Prkce,Ifi44,Rhoq,Bbx,Slco3a1,P2ry14,Hhex,Nek6,Hck,Bfar,Cd34,Il15,Clec4e |
| 7.472e-08 | -16.41 | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | 180 | 37 | 15632 | 1249 |
Igf1r,Hsd17b7,Dnajb2,Cflar,Znrf1,Ikbke,Nr4a3,Dgka,Dcp1a,Kctd12,Ddit4,Cnn3,Zfp36,Ampd3,P4ha1,Dusp6,Notch1,Rab3ip,Crlf3,Ccnd2,Cyth3,Sell,Il4ra,Evl,Tlr6,Cnot4,Ncoa5,Atp13a1,Tapbp,Peli1,Slc44a1,Egr2,Myc,Ets2,Tcf4,Parp8,Abcc5 |
| 7.595e-08 | -16.39 | GNF2_CASP1 | MSigDB lists | GNF2_CASP1 | 102 | 26 | 15632 | 1249 |
Ms4a6d,Tlr2,Hcls1,Tnfaip2,Cd86,Ccr1,Junb,Tnfrsf1b,Bst1,Stx11,Plscr1,Sell,Fgr,Ier2,Hk3,Samhd1,Hck,Pilra,Myd88,Cd302,Dusp1,Aoah,Casp1,Nod2,Fgl2,Igsf6 |
| 7.742e-08 | -16.37 | MODULE_300 | MSigDB lists | MODULE_300 | 33 | 14 | 15632 | 1249 |
Il18,Traf1,Stat1,Cd38,Ahr,Tnfaip3,Il1b,Cd14,Traf2,Cd40,Nfkbia,Tnfrsf1b,Casp1,Dusp6 |
| 7.763e-08 | -16.37 | negative regulation of MAP kinase activity | biological process | GO:0043407 | 68 | 19 | 20694 | 1406 |
Rgs14,Il1b,Ptprj,Spred3,Dusp2,Irak3,Dusp4,Aida,Dusp5,Cav1,Lyn,Spry2,Uchl1,Dusp8,Dnaja1,Spred1,Dusp6,Dusp1,Dusp16 |
| 7.795e-08 | -16.37 | VANHARANTA_UTERINE_FIBROID_DN | MSigDB lists | VANHARANTA_UTERINE_FIBROID_DN | 59 | 19 | 15632 | 1249 |
Klf2,Bcl6,Ptch1,Jun,Cited2,Ezr,Birc3,Gadd45b,Nampt,Hivep2,C1ra,Maff,Nr3c1,Odc1,Trib1,Ier2,Atf3,Egr1,Mdfic |
| 7.822e-08 | -16.36 | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP | MSigDB lists | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP | 158 | 34 | 15632 | 1249 |
Ifnb1,Il6,Timp1,Flt1,Tnf,Itgav,Angpt1,Plau,Col4a2,Hif1a,Calcrl,Sphk1,Col18a1,Jag1,Cxcl2,Pdgfb,Nrp2,Il10,Ccl5,Plaur,Vegfc,Il1b,Pf4,Cxcl1,Notch2,Plat,Tnfaip2,Kdr,Ptgs2,Cxcl10,Il18,Arl5c,Mmp9,Hmox1 |
| 7.964e-08 | -16.35 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | 188 | 38 | 15632 | 1249 |
Oas1g,Uchl1,Trib3,Cxcl10,Bcl2a1a,Trem1,Wdr43,Ifit1bl2,Gdf15,Dusp6,Adap2,Slc9a1,Csf1,Ext1,Phlda1,Flnb,Trip13,Inhba,Oas1a,Ch25h,Usp18,Ccnd2,Cd180,Isg15,Arl4a,Arg2,Fabp3,Slc16a1,Olr1,Dusp14,Ppfibp1,Ifit1bl1,Bcl2a1b,Dhrs9,Ppp1r14b,Homer1,Ifi44,Bcl2a1d |
| 7.964e-08 | -16.35 | GSE27786_LIN_NEG_VS_CD8_TCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_CD8_TCELL_DN | 188 | 38 | 15632 | 1249 |
Slfn9,Cd82,Ap3m2,Socs3,Stat1,Parp3,Itpkc,Tmod3,Chic2,Asb13,Spata5l1,Nmi,Slc39a14,Stoml1,Ankib1,Itgal,Plekha2,Irf7,Ifit1,Cd38,Mark2,Mcmbp,Tnks1bp1,Psme1,Ccnd2,Pttg1,Ddx58,Slc30a1,Rtp4,Trim12c,Slfn8,Cept1,Mdm2,Aebp2,Samd9l,Nlrc5,Crbn,Cst7 |
| 8.048e-08 | -16.34 | positive regulation of interleukin-6 production | biological process | GO:0032755 | 96 | 23 | 20694 | 1406 |
Ifih1,Tlr3,Tlr6,Nod1,Nod2,Ddx58,Tlr2,Lgals9,Il1rn,Il1b,Tlr1,Il6,Ptafr,Ripk2,Tnf,Il1a,Tlr9,Tnfsf9,Myd88,Stat3,Adora2b,Arid5a,Tnfsf4 |
| 8.070e-08 | -16.33 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | 173 | 36 | 15632 | 1249 |
Irf8,Lcp2,Itgal,Hdc,Birc3,Tuba4a,Csf1,Slc7a5,Tgfbi,Slc43a3,Acsl1,Egr3,Smox,Cd55,Dyrk2,Abcc4,Cflar,Il1rn,Cd82,Rgs14,Mgat1,Plac8,Ccl12,Cst7,Slc16a3,Ccnd1,Nod2,Gsr,Gpr35,Fpr2,Socs1,Slco3a1,Rhoh,Bcor,Slc48a1,Sla |
| 8.070e-08 | -16.33 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_UP | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_UP | 173 | 36 | 15632 | 1249 |
Egr3,Ebi3,Ifi35,Itga5,Bcl2a1a,Rnaset2b,Pmepa1,Rnaset2a,Samsn1,Gna15,Nfkbib,Slc39a14,Il12rb1,Rasgrp1,Cd180,Kmo,Traf1,Cd83,Batf,Myd88,Cd164,Mvp,Tap1,Srm,Bcl2a1b,Dhrs9,Irf4,Parp14,Dusp2,Il4i1,Ly75,Egr2,Nfkbie,B3gnt5,Bcl2a1d,Gadd45g |
| 8.207e-08 | -16.32 | GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY | 151 | 33 | 15632 | 1249 |
Nr3c1,Stat3,Nod2,Nr4a1,Nfkbia,Flt1,Src,Dnaja1,Rnf34,Nod1,Tnfaip3,Ahr,Daxx,Pml,Nr1h3,Ifih1,Ddx58,Tab2,Med13,Ccne1,Ikbkg,Rnf14,Pdk3,Casp8,Irf7,Irak2,Notch2,Jak2,Pmepa1,Dcbld2,Ripk2,Nr4a3,Pim1 |
| 8.265e-08 | -16.31 | PYRIN | smart domains | SM01289 | 27 | 13 | 9567 | 823 |
Ifi204,Ifi203,Ifi213,Ifi211,Mndal,Ifi214,Ifi205,Nlrp3,Mefv,Ifi207,Ifi208,Aim2,Ifi209 |
| 8.382e-08 | -16.29 | GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_UP | MSigDB lists | GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_UP | 196 | 39 | 15632 | 1249 |
Zc3h12c,Irf8,Ccr1,Pdk3,Tor3a,Myadm,Snx2,Kctd12,Plscr1,Lyn,Il18,Map3k8,Mtdh,Tmod3,Ell2,Clic4,Cyfip1,Tiparp,Tpst1,Tcf4,Cd40,Plac8,Syk,Fgl2,Fcgr2b,Ctsc,Carhsp1,Prkce,Il4i1,Myc,Rhoq,Cd180,Tmem176b,Hhex,Mcoln2,Pml,Hck,Il15,Ciita |
| 8.398e-08 | -16.29 | PID_HIF1_TFPATHWAY | MSigDB lists | PID_HIF1_TFPATHWAY | 65 | 20 | 15632 | 1249 |
Pfkl,Pgk1,Pfkfb3,Hif1a,Hmox1,Ldha,Egln3,Hk2,Abcb1a,Edn1,Bnip3,Cp,Fos,Cited2,Slc2a1,Jun,Eno1,Nos2,Serpine1,Hk1 |
| 8.465e-08 | -16.28 | GO_REGULATION_OF_TYPE_I_INTERFERON_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_TYPE_I_INTERFERON_MEDIATED_SIGNALING_PATHWAY | 38 | 15 | 15632 | 1249 |
Adar,Ifna6,Ifna1,Ifna2,Tyk2,Ifnb1,Ifna5,Stat1,Ifnar1,Nlrc5,Mul1,Irf7,Ptpn2,Usp18,Stat2 |
| 8.465e-08 | -16.28 | KERLEY_RESPONSE_TO_CISPLATIN_UP | MSigDB lists | KERLEY_RESPONSE_TO_CISPLATIN_UP | 38 | 15 | 15632 | 1249 |
Cxcl14,Dgka,Btg2,Procr,Ddit4,Cav1,Plk2,Serpine1,Gdf15,Cdkn1a,Plat,Ier3,Fas,Plk3,Dram1 |
| 8.473e-08 | -16.28 | GO_CELLULAR_RESPONSE_TO_MECHANICAL_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_MECHANICAL_STIMULUS | 77 | 22 | 15632 | 1249 |
Tnfrsf8,Myd88,Il1b,Fas,Tlr3,Ptger4,Map2k4,Irf1,Ptgs2,Hif1a,Slc9a1,Bnip3,Kcnj2,Casp2,Nfkb1,Gja1,Casp1,Cnn2,Cd40,Casp8,Cav1,Tnfsf14 |
| 8.561e-08 | -16.27 | GO_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS | MSigDB lists | GO_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS | 116 | 28 | 15632 | 1249 |
Relb,Batf,Il4ra,Icam1,Cd74,Tlr6,Fas,C1ra,Il18bp,Dennd1b,Il6,Irf4,Ctsc,Bcl6,Swap70,Nfkb2,Il12b,Sema4a,Il18,C3,H2-Ab1,Cd55,Ebi3,Pou2f2,Jag1,C1rl,Irf7,H2-Eb1 |
| 8.565e-08 | -16.27 | regulation of type I interferon production | biological process | GO:0032479 | 82 | 21 | 20694 | 1406 |
Zc3hav1,Rel,Nmi,Cgas,Dhx58,Tlr9,Myd88,Irf1,Cd14,Relb,Irf7,Tlr2,Ddx58,Gbp4,Syk,Tlr3,Ifih1,Rnf135,Ifnar1,Stat1,Acod1 |
| 8.604e-08 | -16.27 | COLINA_TARGETS_OF_4EBP1_AND_4EBP2 | MSigDB lists | COLINA_TARGETS_OF_4EBP1_AND_4EBP2 | 326 | 55 | 15632 | 1249 |
Usp18,Gbp3,Isg15,Slco3a1,Ripk3,Gbp2,Cd14,Psmb9,Cd302,Ifit2,Slc16a3,Ccnd1,C1ra,Pnp2,Cp,Ifi44,Fchsd2,Parp3,Abcc4,Vcam1,Acsl5,Osbpl3,Il1rn,Thbs1,Tor1aip1,Nampt,Ccl5,Sesn3,Car13,Parp12,Phlda1,Rtp4,Tpx2,Sdc4,Zbp1,Gng11,Irgm2,Pdpn,Ifi35,Il13ra1,C3,Stat1,Pfkl,Ppfibp2,Plod2,Lcn2,Atm,Psmb8,Eno2,Tor3a,Nfkb1,Ltbp2,Smpdl3b,Hat1,Fabp7 |
| 8.652e-08 | -16.26 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_UP | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_UP | 166 | 35 | 15632 | 1249 |
Hlx,Slc30a4,Marcksl1,Traf1,Olr1,Tnfaip3,Slc16a3,Casp1,P4ha2,Nfkbia,Tank,Pdpn,Gpr35,Nqo1,Dusp4,Dusp5,Kif5c,Map3k8,Il12b,Tnip1,Il1rn,Cflar,Il1b,Ptges,Plaur,Nfkb1,Pde4b,Slc13a3,Dach1,Daam1,Lcp2,Nrp2,Cxcl2,Rapgef2,Pla2g7 |
| 8.670e-08 | -16.26 | cell population proliferation | biological process | GO:0008283 | 576 | 74 | 20694 | 1406 |
Fubp1,Txnrd1,Hmga2,Notch1,Hhex,Plcl2,Il18,Ifna1,Itgal,Sbds,Nr4a3,Mcm10,Ccnd1,Pim1,Riox2,Samd9l,Gja1,Ptch1,Tgfbi,Il18rap,Map2k1,Bmp2,Cd34,Stat3,Fbxo4,Src,Ifna4,Ripk2,Mvp,Pdgfb,Il6,Ebi3,Ifna5,Cd180,Mmp14,Cd74,Il12b,Prkx,Etv6,Fabp7,Myc,Lipg,Junb,Psmb10,Pdgfrb,Malt1,Ifnb1,Uchl1,Notch2,Il15,Nupr1,Csf1,Rab10,Egr1,Larp1,Dach1,Tnfsf4,Ddit4,Irf2,Prdx1,Prdm1,Ifna6,H3f3b,Met,Ascc3,Cx3cl1,Pdpn,Tnf,Cited2,Stat4,Azi2,Abcb1a,Ifna2,Znrf3 |
| 8.683e-08 | -16.26 | GSE17721_POLYIC_VS_CPG_8H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_8H_BMDC_UP | 181 | 37 | 15632 | 1249 |
Tlr9,Atp10a,Endod1,Dio2,Ccl4,Tnfsf10,Pcdh7,Rbms1,Fzd5,Plk2,Cd274,Sesn3,Tor3a,Dgka,Sh3bp4,Zc3h7a,Ociad1,Tpx2,Slc30a1,Pttg1,Nck1,Ddx60,Prpf38a,Dnase1l3,Apaf1,Rbms2,Bcl6,Tpst1,Morc3,Klf3,Crbn,Tapbp,Cept1,Hdac1,Gbp4,Gbp9,Batf2 |
| 8.731e-08 | -16.25 | PDGF_ERK_DN.V1_DN | MSigDB lists | PDGF_ERK_DN.V1_DN | 137 | 31 | 15632 | 1249 |
Bcl9,Rtn2,Zfp324,Maff,Junb,Dusp6,Nfil3,Smox,Dyrk2,Dtx2,Trib1,Il2rg,Mafg,Spry2,Myc,Dusp8,Tnfsf8,Phlpp1,Ccng2,Morc3,Dusp1,Nfkbia,Ppp6r1,Klhl25,Mgat1,Jun,Zbtb5,Hinfp,Irf2,Egr1,Rnf139 |
| 8.739e-08 | -16.25 | protein metabolic process | biological process | GO:0019538 | 3559 | 316 | 20694 | 1406 |
Ctsc,Bmp2,Casp2,Ubr4,Trem1,Fbxo4,Prnp,Ube2l6,Grk3,Prdm9,Thbs1,Cpeb4,Plk2,Lox,Dusp8,Saa3,Otud1,Cflar,Sap30,Acvr1b,Hif1a,Pgap2,Dusp1,Ccnd2,Kdm4a,Isg15,Sla,Ppp2r3a,Pim3,Tmtc2,Il1b,Acp2,Dtx2,Mppe1,Tet2,Mapkapk2,Trib3,Extl2,St3gal5,Btg2,Mdm2,Mlkl,Keap1,Prkce,Cdk5r1,Ccnd1,Ppp2r5a,Ppm1l,Ifnar1,Itgav,Casp3,Tlr3,Plat,Uba7,Trim56,Casp8,Denr,Myd88,Serp1,Met,Acvrl1,Rnf19a,Nck1,Mdfic,Rffl,Sik3,Phlpp2,Gfpt1,Kdr,Egr2,Dusp6,Setdb2,Ubash3b,Cnot4,Kdm6b,Plod2,Mark2,Psmb10,Ppp1r15a,Mmp25,Dusp4,Bnip3,Plod3,Srgn,Tmem67,Ext1,Fut8,Ube2e2,Kmt5a,Map2k1,Pdk3,Eif4g2,Trim12c,Tpst1,Hck,Parp12,Phlda1,Src,Peli1,Psma6,Ikbke,Dpy19l1,Gpc1,Tnfsf15,Ube2e1,Flt1,Usp12,Lif,Pdgfb,P4ha2,Ero1l,Ranbp2,Akt3,Rnf139,Spsb1,Ripk3,Tyk2,Il12rb1,Rictor,Pgk1,Inhba,Trib1,Irf7,Tnfaip3,Usp35,Bcor,Jak2,Sphk1,Hat1,Scyl2,St3gal1,Parp14,Birc3,Psmb8,Arrdc4,Gtpbp2,Tlr9,Psmb9,Med21,Parp8,Eif2ak2,Hopx,Stat5a,Trim12a,Ppm1k,Map3k8,Arid4a,Rnf34,Znrf3,Dcun1d3,Herc6,Eef1e1,Mecp2,Usp31,Prag1,Prkx,Kdm5b,Ptk2,Ppp4r2,Rnf19b,Pdgfrb,Ptpn2,Myc,Il15,Nupr1,Dnajb2,Ccng2,Dusp16,Birc2,Dusp14,Ifih1,Ppp2r2a,Dusp2,Mrpl52,F10,Dusp5,Cdyl,Sde2,Mgat1,Ankib1,Ksr1,Olr1,Mmd,Atm,Axl,Trim13,Sirt1,Mmp9,Arf4,Arel1,Fam20c,Parp11,C1rl,Trim30a,Tnip1,St3gal3,Osm,Chst11,Lyn,Htr2b,Ptch1,Usp18,Armc8,St3gal6,Pim2,Parp10,Cpd,Ccnj,Ccl12,Eya4,Pml,Dse,Bfar,Tnf,Plk3,Mapkbp1,Lap3,Pcgf5,Trim36,Syk,Rnf135,Stat4,Adgb,Dusp28,Parp3,P4ha1,Malt1,Psmb6,Rnf31,Hk1,Ccl5,Kat2b,Jmjd6,Nod1,Uchl1,Dr1,Wars,Igf1r,Larp1,Fgr,Vrk2,Map3k6,Nlgn2,Ptprj,Ldlr,Tlk2,Casp1,Jarid2,Ccne1,Gcnt2,Dyrk2,B3gnt5,Map4k4,Casp4,Mvp,Rnf14,Nos2,Irgm2,Stk40,Parp9,Ripk2,Mul1,Htra1,Traf2,Nek6,Usp25,Mocs1,Chmp4b,Fgl2,Il18,Zc3h12a,Irak2,Tiparp,Tlr2,Pim1,Usp53,Plpp1,Crbn,Vcpip1,Znrf1,Map2k4,Ppp1r15b,Acvr1,S100a8,Plau,Pigv,Adam19,Klhl25,Rars,Phlpp1,Hdac1,Naa25,Egln3,Usp42,Mmp13,Ptger4,Casp7,Ccr3,Sgk3,Mmp14,Mtmr14,C1ra,Morc3,Cop1,Zfp36,Lnpep,Ep400,Irf4,Gadd45g,Svbp,Dtx3l,Irak3,Ube2f,Nsd3,Trim21,Socs7 |
| 8.914e-08 | -16.23 | negative regulation of tumor necrosis factor production | biological process | GO:0032720 | 62 | 18 | 20694 | 1406 |
Zc3h12a,Acp5,Sirt1,Irak3,Cd34,Nfkbil1,Axl,Il10,Tlr6,Arg2,Errfi1,Ptger4,Cx3cl1,Trim30a,Gpr18,Tspo,Tnfaip3,Nod2 |
| 9.078e-08 | -16.21 | DODD_NASOPHARYNGEAL_CARCINOMA_DN | MSigDB lists | DODD_NASOPHARYNGEAL_CARCINOMA_DN | 1176 | 144 | 15632 | 1249 |
Itgav,Eif2ak2,Ifrd1,Vcan,Tor1aip2,Ctsc,Ggct,Tpx2,Papss2,Znrf3,Tpi1,Fas,Ddx60,Rbl1,Slc16a1,Cd80,Clec4e,Col4a2,Pilra,Il15,Lap3,Cenpj,Cav1,Vezt,Xaf1,Stx6,Etv6,Mmd,Map2k4,Mthfd2,Ifit3b,Tnip3,Dram1,Wdr43,Vrk2,Lhx2,Col27a1,Ccl4,Fscn1,Oas3,Ddhd1,Dpy19l1,Rsad2,Ifi44,1110038F14Rik,Cycs,Phgdh,Ifih1,Gbp3,Usp18,Zfp281,Plagl2,Cd14,Ube2f,Vps54,Serpine1,Med21,Asns,Cacybp,Cd274,Gja1,Fcgr4,Ccr1,Parp12,Inhba,Tmeff1,Ext1,Frmd4a,Mcm6,Ripk2,Naa25,Pgk1,Rcl1,Pkp4,Kitl,Dock4,Msr1,Bcl2l11,Ccl12,Cenpe,Taf4b,Sdc2,Rai14,Slc44a1,Ccl2,Myc,Igsf6,Tgs1,Sass6,Prnp,Pttg1,Ccnd2,Adar,Pnpt1,Plau,Ifit3,Ankib1,Psat1,Eef1e1,Pla2g7,Slc39a14,Pdss1,Timeless,Akt3,Aida,Rcn1,Ppa1,Stat1,Denr,Cd200,Etnk1,Tnfsf4,Ap3m2,Eno1,Rbbp8,Gpsm2,Tank,Src,Axl,Minpp1,Socs1,Icam1,Ddx58,Mcm10,Marcksl1,Magohb,Mcmbp,Bfar,Ascc3,Fubp1,Snx10,Mthfd1l,Tnfsf15,Slc7a5,Rilpl1,Cxcl10,Ptgs2,Scyl2,Ldha,Usp31,Fmnl2,Il15ra,Gca,Dek |
| 9.200e-08 | -16.20 | KIM_WT1_TARGETS_8HR_UP | MSigDB lists | KIM_WT1_TARGETS_8HR_UP | 159 | 34 | 15632 | 1249 |
Aff1,Pdgfc,Zc3hav1,Il4ra,Sphk1,Cx3cl1,Rhoq,Bcl2a1d,Hsph1,Bcl2a1b,Swap70,Jun,Hmga1,Zyx,Rhof,Bcl2a1a,Pcdh7,Adam19,Plaur,Glrx,St3gal1,Trib1,Pim1,Dnajb4,Lyn,Pik3cd,Csf1,Spen,Maff,Junb,Eno2,Tuba4a,Gem,Serpine1 |
| 9.200e-08 | -16.20 | GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_UP | MSigDB lists | GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_UP | 159 | 34 | 15632 | 1249 |
Nfkbia,Dusp1,Apobec3,Txnrd1,Ccl12,Tpst1,Rhof,Ets2,Jun,Tnc,Cycs,Optn,Psme1,Atf3,Csrnp1,Upp1,Hif1a,Zbtb5,Sdc4,Bmp2,Tnfaip3,Ednrb,Tifa,Rhou,Cxcl2,Rtn1,Ptgs2,Ier3,Map3k8,Cxcl10,Fam111a,Cxcl1,Col27a1,Dusp16 |
| 9.202e-08 | -16.20 | signaling receptor activator activity | molecular function | GO:0030546 | 494 | 67 | 20217 | 1400 |
Cxcl14,Flrt2,Tnfsf9,Csf3,Ccl22,Sema4a,Ccl5,Jag1,Cxcl3,Tnfsf8,Il15,Sema3c,Il12b,Cxcl1,Pdgfc,Cxcl11,Timp1,Tnf,Ifna5,Ifna2,Ifna1,Il6,Insl6,Saa3,Cxcl10,Nampt,Ifna4,Il1a,Il1rn,Osm,Tnfsf10,Gdf15,Ccl12,Pdgfb,Sema4c,Clcf1,Kitl,Tnfsf4,Ifna6,Il1b,Inhba,Cx3cl1,Il27,Flrt3,Il10,Cxcl9,Cxcl2,Lif,Pf4,Ccl4,Osgin2,Tnfsf14,Ccl8,Cdc42ep2,Ccl2,Tnfsf15,Ifnb1,Il18,Vegfc,Ccl9,Ccl3,Bmp2,Csf1,Prkce,Ebi3,Edn1,Ccl7 |
| 9.216e-08 | -16.20 | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | 189 | 38 | 15632 | 1249 |
Osbpl3,Bcl2a1a,Nfil3,Dusp5,Endod1,Map3k8,Lyn,Plscr1,Pdlim7,Stx11,Tdrd7,Mmd,Vps54,Tnfsf14,Gna15,Samsn1,Ahr,Rhoc,Ppfibp1,Cd38,Hhex,Plk3,Malt1,Gbp3,Ubash3b,Cd74,Rab19,Slc15a3,Tnfsf8,Slc39a4,Casp3,Bcl2a1d,Gpr68,Chst11,Itgav,Bcl2a1b,Cst7,Casp1 |
| 9.216e-08 | -16.20 | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_DN | 189 | 38 | 15632 | 1249 |
Bcl2a1a,Irak2,Ralgds,Igf1r,Frmd6,Gfi1,Ebi3,Cd200,Map3k8,Plscr1,Slc4a7,P4ha1,Lad1,Samsn1,Vps54,Sav1,Nod1,Cd83,Batf,Spred1,Samhd1,Cyth3,Kat2b,Prnp,Icam1,Ppm1l,Arrdc4,Gbp3,Cish,Phlpp1,Bcl2a1d,Gadd45g,Cpd,Bcl2a1b,Rapgef5,Tspan3,Homer1,Swap70 |
| 9.397e-08 | -16.18 | LEE_NEURAL_CREST_STEM_CELL_DN | MSigDB lists | LEE_NEURAL_CREST_STEM_CELL_DN | 103 | 26 | 15632 | 1249 |
Palld,Plagl1,Etv5,Enpp4,Notch1,Mtus1,Fos,Fut8,Spry2,Sat1,Lztfl1,Cd82,Lhx2,Agpat4,Mfap3l,Gdf15,Dusp6,Fzd5,Plk2,Nos2,Hdc,Fabp7,Pstpip2,Htra1,Maff,Syne2 |
| 9.408e-08 | -16.18 | GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP | MSigDB lists | GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP | 174 | 36 | 15632 | 1249 |
Tlr1,Egln3,Maff,Nampt,Ccnj,Ifit3,P2ry2,Rbms1,Bcl2a1a,Rap2c,Kitl,Ldlr,Gng12,Pim1,Trib1,Irf1,Ifit3b,Ier3,Fpr1,Sat1,Arhgap26,Nfkbie,Bcl2a1d,Nfkbia,Tnf,Flrt3,Bcl2a1b,Bcl6,Cd83,Zbp1,Bmp2,Tnfrsf8,Hk3,Hlx,Upp1,Nlrp3 |
| 9.408e-08 | -16.18 | GSE1460_DP_VS_CD4_THYMOCYTE_DN | MSigDB lists | GSE1460_DP_VS_CD4_THYMOCYTE_DN | 174 | 36 | 15632 | 1249 |
Fcgr2b,Ifi44,Rsad2,Bcl2a1d,Plac8,Ehd1,Casp1,Sp140,Bcl2a1b,B4galt4,Gbp2,Ahr,Evl,Ddx60,Abr,Asap3,Ccnd2,Sell,Il4ra,Oas2,Pde4b,Tuba4a,Klf2,Lap3,Bcl2a1a,Rgs1,Tnfsf10,Inpp1,Ppfibp2,Sp110,Cd55,Stat1,Acvr1b,Nr4a3,Fpr1,Pik3cd |
| 9.409e-08 | -16.18 | positive regulation of angiogenesis | biological process | GO:0045766 | 185 | 34 | 20694 | 1406 |
Itga5,Hif1a,Flt1,Kdr,Vegfc,Il1a,Cx3cl1,Ptgs2,Stat3,Acvrl1,Cd34,Thbs1,Plk2,Il10,Cx3cr1,Hk2,Tlr3,Cd40,Mtdh,Sphk1,Cysltr2,Hmox1,Ccl5,Serpine1,Mmp9,Sirt1,Zc3h12a,Ccr3,Hmga2,Itgb8,Il1b,Pik3r6,C3,Akt3 |
| 9.457e-08 | -16.17 | SWEET_LUNG_CANCER_KRAS_DN | MSigDB lists | SWEET_LUNG_CANCER_KRAS_DN | 396 | 63 | 15632 | 1249 |
Sema3c,Ifit3,Cav1,Ptch1,Gbp7,S100a8,Ednrb,Ccrl2,Kctd12,Rcn1,Ms4a6d,Adrb2,Ifit3b,Acsl1,C3,Gsta3,Abcc1,Kdr,Tspan3,Ets2,Jun,Flt1,Nfkbia,Gadd45b,Tagln,Psip1,Cxcl14,Edn1,Prkce,Pgm1,Cyth3,Papss2,Fas,Klf7,Ahr,Angpt1,Gng11,Klf2,Hopx,Myo1b,Pdgfrb,Tmeff1,Slc7a5,Lox,Hp,Il1b,Ptges,Clic4,Kitl,Arhgef3,Tcf4,Dusp1,Fgl2,Acvrl1,Cp,Usp18,Calcrl,Gbp3,Ifih1,Psmb10,Slco3a1,Hck,Gnb4 |
| 9.459e-08 | -16.17 | negative regulation of cellular component organization | biological process | GO:0051129 | 718 | 87 | 20694 | 1406 |
Stat1,Crbn,Bcor,Rap1gap2,Tlr2,Tnfrsf1b,Swap70,Notch1,Chmp4b,Gfi1,Xaf1,Cxcl10,Lif,Tmod3,Mul1,Lpar1,Lrp4,Src,Map4k4,Sema3c,Ldlr,Jarid2,Sema4c,Birc2,Stap1,Ifrd1,Trip13,Antxr1,Hspa2,Nupr1,Dnajb2,Spry2,Carmil1,Tmsb10,Irak3,Nr1h3,Prag1,Mmp14,Ptk2,Dync1i2,Rab3ip,Cenpe,Ptger4,Mecp2,Tspo,Evl,Dcp2,Mllt6,Lmo4,Dbnl,Psmd10,Cdk5r1,Myadm,Trim30a,Osm,Kremen1,Cav1,Sirt1,Ier3,Mdm2,Pttg1,Il15ra,Higd1a,Kdm4a,Atm,Mid1,Cflar,Prnp,Plk2,Rapgef2,Cd38,Sema4a,Tmem67,Rgcc,Rabgef1,Pmepa1,Kat2b,Bnip3,Mefv,Stxbp1,Tnf,Met,Acvrl1,H3f3b,Katna1,Pml,Siglece |
| 9.870e-08 | -16.13 | regulation of interleukin-17 production | biological process | GO:0032660 | 33 | 13 | 20694 | 1406 |
Osm,Nod2,Il15,Tlr2,Sphk1,Il6,Arg2,Arid5a,Il12b,Tnfsf4,Prnp,Myd88,Il18 |
| 1.001e-07 | -16.12 | Ig-like_fold | interpro domains | IPR013783 | 736 | 92 | 19984 | 1430 |
Sema3c,Nectin4,H2-T24,F11r,Slamf9,B430306N03Rik,Nfkb2,Axl,Cd86,Vasn,Trem1,Tnc,Kdr,Tapbp,Il18rap,Met,Pvr,Cd274,Cd300lf,Vcam1,Cd83,Ptprj,Pilrb2,A530064D06Rik,H2-Eb1,Fndc3a,Arel1,Tapbpl,Flrt2,Milr1,Treml2,Mfap3l,Ebi3,Slamf8,Icosl,Gm5150,Igsf6,Flt1,Sema4c,Rel,Siglece,Pdgfrb,Igsf9,Cd200r4,Tarm1,Palld,Fcgr2b,Fcgr1,Igf1r,Il13ra1,Cd300e,H2-T22,Clmp,Scn1b,Fcgr4,Nxpe3,Malt1,Ifnar1,H2-Q7,Il4ra,H2-Q6,Cd80,H2-M2,H2-Ab1,Gbe1,Lrp11,Inpp5b,Sema4a,Mid1,Slamf7,Pilrb1,Cd200,Relb,Crlf3,Il12rb1,Icam1,Il12b,H2-Q4,Il2rg,Treml4,Nectin2,Nfkb1,Igsf8,Pilra,Csf3r,Vcan,C3,Flnb,Il18bp,Trim36,H2-Aa,H2-T10 |
| 1.008e-07 | -16.11 | GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP | MSigDB lists | GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP | 182 | 37 | 15632 | 1249 |
Kcnj2,Igsf6,Vcan,Src,Aoah,Slc25a37,Dse,Msr1,Dock4,Tcf4,Gnb4,Pilra,Plau,Cd14,Hck,Fpr2,Dmxl2,Pstpip2,Nrp2,Alas1,Wars,Rhou,AA467197,Cd86,Clic4,Gca,Cd300lf,Fam20c,Tfec,Vrk2,Hmox1,Il13ra1,Tgfbi,Ptafr,Fpr1,Rab20,Tlr2 |
| 1.008e-07 | -16.11 | GSE19401_UNSTIM_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_UNSTIM_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_UP | 182 | 37 | 15632 | 1249 |
Rsad2,Tapbp,Fgl2,Ly75,Itpr1,Fos,Plod3,Srm,Slc16a3,Apobec3,Dusp1,Spn,Mvp,Hk3,Tspo,Fcgr1,Fgr,Psmb10,Ccl22,Ier2,Aim2,H2-Aa,St3gal5,Pdgfb,Ddit4,Irf7,Lmo4,Fosb,Itgal,S100a8,Dnajb2,Stip1,Ikbke,Il2rg,Psmb6,Mmp9,H2-Ab1 |
| 1.011e-07 | -16.11 | GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 145 | 32 | 15632 | 1249 |
Hmox1,Il1b,Pf4,Tnfsf10,Thbs1,Ppp2r1b,Cflar,Acsl5,Casp8,Serpine1,Cav1,Inhba,Traf1,Cx3cl1,Il1a,Phip,Icam1,Pml,Atf3,Fas,Tnfaip3,Gclc,Rnf34,Hspa1a,Traf2,Itgav,Cx3cr1,Tnf,Src,Acvr1,Rffl,Gclm |
| 1.011e-07 | -16.11 | regulation of neuroinflammatory response | biological process | GO:0150077 | 28 | 12 | 20694 | 1406 |
Ldlr,Ctsc,Cst7,Tnfrsf1b,Cd200r4,Cd200,Nupr1,Cx3cl1,Ptgs2,Stap1,Sphk1,Atm |
| 1.012e-07 | -16.11 | GSE19198_6H_VS_24H_IL21_TREATED_TCELL_UP | MSigDB lists | GSE19198_6H_VS_24H_IL21_TREATED_TCELL_UP | 167 | 35 | 15632 | 1249 |
Ccl5,Plek,Tor3a,Birc3,Serpine1,Itgal,Tnfsf14,Cd86,Pdlim7,Psme2,Rab10,Uba7,Nr4a3,Il2rg,Cd82,Slc29a3,Plaur,Slc7a11,Txnrd1,Cd40,Aftph,Egr2,Ly75,Rhoq,Edn1,Micall2,Nfkbie,Marcksl1,Atf3,Traf1,Nr1h3,Slamf7,Cd83,Sgcb,Olr1 |
| 1.012e-07 | -16.11 | GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN | MSigDB lists | GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN | 167 | 35 | 15632 | 1249 |
Map4k4,Card6,Myadm,Klf2,Flnb,Med13,Cd69,Dgka,Snx2,Rictor,Stat4,Smc5,Dyrk2,Cd200,Cd55,Nr4a3,Aida,Klf6,Gramd1a,Bcl6,Cited2,Arhgef3,Fchsd2,Stap1,Tbc1d1,B3gnt5,Sele,Mecp2,Egr1,Rhoh,Irf2,Isg15,Sell,Ciita,Samhd1 |
| 1.019e-07 | -16.10 | negative regulation of protein transport | biological process | GO:0051224 | 203 | 36 | 20694 | 1406 |
Pfkl,Tlr6,Tnfaip3,Klf7,Rabgef1,Cd200,Srgn,Frmd4a,Rgcc,Zc3h12a,Lgals9,Il1b,Txn1,Nlrp3,Pim3,Nr1h3,Il6,Ptger4,Pde3b,Arg2,Rab11fip1,Rsad2,Mapkbp1,Tnf,Cx3cl1,Gbp4,Rhbdf2,Mdfic,Map4k4,Hdac1,Cd34,Angpt1,Ezr,Il10,Pml,Tnfsf4 |
| 1.024e-07 | -16.09 | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 644 | 90 | 15632 | 1249 |
Mdm2,Casp3,Fut8,Dbnl,Hspa1a,Hsph1,Daxx,Mdfic,Bfar,Nod1,Bmp2,Il1a,Hif1a,Pml,Txn1,Gch1,Map4k4,Dek,Grina,Larp1,Zc3h12a,Uchl1,Nod2,Edn1,Myc,Psmd10,Map3k6,Ezr,Bcl2l11,Chmp4b,Prdx1,Pnpt1,Trim13,Tlr6,Mapkapk2,Sirt1,Rasgrp1,Met,Eef1e1,Igf1r,Kdr,Aida,Adrb2,Ier3,Fignl2,Nox1,Traf2,Bcl6,Tnf,Cd74,Fzd5,Ppp1r15a,Map2k1,Atp6v1d,Il1b,Nr4a3,Tlr3,Hp,Ripk2,Phlpp1,Scarf1,Mid1,Gadd45g,Bnip3,Ptpn2,Hmga1,Dnaja1,Gadd45b,Eif2ak2,Syk,Sqstm1,Sod2,Spred1,Cd34,Tspo,Cdk5r1,Pikfyve,Mul1,Nck1,Nek6,Cdkn2d,Usp25,Ppp4r2,Cav1,Atm,Ppp1r15b,Rab20,Lyn,Sema4c,Tlr9 |
| 1.041e-07 | -16.08 | SMIRNOV_RESPONSE_TO_IR_6HR_UP | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_6HR_UP | 138 | 31 | 15632 | 1249 |
Gdf15,Map4k4,Gch1,Pde4b,Plk2,Btg2,Procr,Pstpip2,Csf1,Stx6,Itpkc,Tnfsf4,Rnf19b,Dram1,Ier3,Cdc42ep4,Dnajb4,Inpp1,Ralgds,Cdkn1a,Apobec3,Dse,Mdm2,Fas,Atf3,Slc30a1,Socs1,Sdc1,Dusp14,Apaf1,Notch1 |
| 1.047e-07 | -16.07 | NFKAPPAB65_01 | MSigDB lists | NFKAPPAB65_01 | 221 | 42 | 15632 | 1249 |
Sdc4,Il27,Relb,Rnd1,Icam1,Slc44a1,Lrch1,Ifnb1,S1pr2,Mllt6,Rin2,Nfkbia,Gadd45b,Parp8,Dock4,Cd40,Zmynd15,Rap2c,Tnip1,Nfkb2,Rbms1,Ptges,Mob3c,Itpkc,Uaca,Gng4,Mmp9,Cxcl10,Map3k8,Ier3,Slamf8,Tnfsf15,Nfkbib,Zeb1,Cd69,Nfkbid,Tnfrsf1b,Ccl5,Birc3,Rel,Cd86,Col11a2 |
| 1.048e-07 | -16.07 | positive regulation of neuron death | biological process | GO:1901216 | 120 | 26 | 20694 | 1406 |
Casp2,Casp8,Ddit4,Map2k4,Fcgr2b,Nr3c1,Prnp,Bcl2l11,Jun,Fos,Tnf,Daxx,Ccl3,Atm,Pmaip1,Kmo,Agrn,Il1b,Optn,Nqo1,Il18,Egr1,Fas,Cdk5r1,Casp3,Tlr6 |
| 1.056e-07 | -16.06 | AMIT_SERUM_RESPONSE_120_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_120_MCF10A | 60 | 19 | 15632 | 1249 |
Pim1,Irs2,Sertad3,Sphk1,Cxcl10,Cd55,Lif,Plaur,Plagl2,Rnd3,Clcf1,Bmp2,Ets2,Ezr,Junb,Gadd45b,Maff,Trim21,Edn1 |
| 1.059e-07 | -16.06 | P-loop_NTPase | interpro domains | IPR027417 | 876 | 105 | 19984 | 1430 |
Helz2,Spata5l1,Ddx58,Arl5c,Abcc5,Gbp2,Chd9,Rhoc,Smc5,Iigp1,Rab32,Slfn9,Gm4841,Rab21,Fignl2,Ifi47,Znfx1,Ep400,Mcm6,Tap1,Gm12250,Mx1,Ddx4,Rab19,Irgm1,Nlrp3,Mcm9,Myo1b,Ddx60,Trip13,Katna1,Dck,Gbp7,Mdn1,Gbp3,Tap2,Gbp9,Rab9,Nlrc5,Rac3,Cacnb3,F830016B08Rik,Apaf1,Gbp4,Gtpbp2,Ascc3,Rab20,Rhof,Cmpk2,Ust,Pfkfb3,Cenpe,Nod2,Mx2,Gm12185,Mov10,Abcc4,Kif3c,Arf4,Ak4,Ehd1,Arl4a,Ifi44,Ciita,Papss2,Slfn5,Gm4070,Tpst1,Rnd3,Dhx58,Gvin1,Abcb1a,Myo10,Rras2,Ift22,Gm5431,Abcc1,Tor3a,Rap2c,Gna15,Gbp2b,9930111J21Rik2,Rnd1,Mthfd1l,Cnp,Nlrc4,Rhoq,Dync1h1,Gem,Gbp8,Igtp,Irgm2,Kif5c,Mpp7,Slfn8,Rhou,Arl5b,Tgtp1,Rab10,Rhoh,Nkiras1,9930111J21Rik1,Gm4951,Kif9,Ifih1 |
| 1.064e-07 | -16.06 | eosinophil migration | biological process | GO:0072677 | 19 | 10 | 20694 | 1406 |
Ccl8,Ccl22,Ccl4,Ccl2,Ccl5,Cx3cl1,Ccl9,Ccl12,Ccr3,Ccl7 |
| 1.064e-07 | -16.06 | positive regulation of T cell cytokine production | biological process | GO:0002726 | 19 | 10 | 20694 | 1406 |
Fzd5,Malt1,Traf2,Il18,Il6,Il1b,Arid5a,Nlrp3,Tnfsf4,Rsad2 |
| 1.065e-07 | -16.06 | GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_DN | MSigDB lists | GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_DN | 190 | 38 | 15632 | 1249 |
Traf1,Ifih1,Atp11a,Icam1,Pttg1,Tmem176b,Psme1,Prdm1,Fas,Notch1,Rgs3,Gpc1,Myd88,Batf,Eno1,Ifit2,Klf3,Stk40,Cish,Mthfd2,Cxcl10,Ifit3b,Pim1,Ptger4,Glrx,Frmd6,Pkp4,Cd82,Atp6v1d,Ifit3,Hopx,Ccl5,Psmb8,Tmem176a,Stx6,Il18rap,Nmi,Reps1 |
| 1.080e-07 | -16.04 | GSE29618_BCELL_VS_MDC_UP | MSigDB lists | GSE29618_BCELL_VS_MDC_UP | 160 | 34 | 15632 | 1249 |
Zhx2,Adam19,Arid5b,Kcna3,Odc1,Pim2,Ell2,Rasgrp1,Snx2,Isg20,Plekha2,Klf2,Tuba4a,Map4k4,Birc3,Klf7,Rras2,Pikfyve,Il4ra,Rhoh,Egr1,Aim2,Ift57,Optn,Stap1,Peli1,Fchsd2,Myc,Swap70,Itpr1,Gpr18,Tspan3,Sp140,Ezr |
| 1.086e-07 | -16.04 | GO_RESPONSE_TO_DRUG | MSigDB lists | GO_RESPONSE_TO_DRUG | 424 | 66 | 15632 | 1249 |
Vegfc,Il1b,Htr2b,Thbs1,Ak4,Ptgs2,Lox,Tlr3,Ptger4,Slc31a1,Ldha,Inhba,Mmp13,Fzd1,Pdgfb,Cd86,Ppp1r15a,Fosb,Pde4b,Junb,Ccl5,Dusp6,Cd38,Icam1,Hif1a,Fabp3,Socs1,Aim2,Mthfr,Mdm2,Ccnd1,Stat3,Casp3,Pnp2,Psmb9,Src,Abcc1,Prkar2b,Cdkn1a,Lyn,Acsl1,Hmgcs1,Socs3,Cd69,Slc9a1,Cav1,Sema3c,Il10,Nos2,Ptch1,Ccne1,Htr2a,Tspo,Prnp,Fas,Col18a1,Lrp8,Gclm,Edn1,Abcb1a,Myc,Il6,Fos,Jun,Ass1,Ccl12 |
| 1.095e-07 | -16.03 | GSE7852_THYMUS_VS_FAT_TREG_DN | MSigDB lists | GSE7852_THYMUS_VS_FAT_TREG_DN | 175 | 36 | 15632 | 1249 |
Cdkn1a,Dnajb2,Il15ra,Adrb2,Ier3,Zc3h12a,Ell2,Mmp9,Dram1,Rap1gap2,Maff,Stx11,Il18rap,Il12rb1,Nfkbib,Flnb,Phlda1,Samsn1,Fzd5,Jdp2,Brd2,Gch1,Tshz1,Rhoc,Enpp4,Pim3,Nfkbie,S1pr2,Abcb1a,Ccr3,Tiparp,Sqstm1,Itgav,Apobec3,Trim36,Tnf |
| 1.095e-07 | -16.03 | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_DN | 175 | 36 | 15632 | 1249 |
Eef1e1,Tdrd7,Rasgrp1,Psme2,Htra1,Trim21,Dusp6,Brd2,Ifit1bl2,Fcgr4,Wdr43,Stip1,Gcnt2,Acsl1,Serpinb9,Cxcl10,Tlr2,Dnajb4,Slc31a1,Hp,Rsad2,Mid1,Optn,Nat2,Cd40,Psmb9,Fos,Sod2,Ifit1bl1,Eif2ak2,Pbx1,Isg15,Nr1h3,Lrp8,Prdm1,Fas |
| 1.110e-07 | -16.01 | JAK-STAT signaling | KEGG pathways | mmu_M00684 | 19 | 11 | 7931 | 713 |
Stat5a,Stat1,Cish,Socs1,Tyk2,Jak2,Stat3,Stat2,Stat4,Socs3,Socs7 |
| 1.110e-07 | -16.01 | JAK-STAT signaling | KEGG pathways | M00684 | 19 | 11 | 7931 | 713 |
Tyk2,Stat1,Cish,Socs1,Stat5a,Socs3,Socs7,Stat4,Stat3,Jak2,Stat2 |
| 1.118e-07 | -16.01 | Epstein-Barr virus infection | KEGG pathways | mmu05169 | 214 | 44 | 7931 | 713 |
Traf2,H2-Q6,Traf5,H2-M2,Il10,Pik3cd,Stat3,Cd38,Nfkbia,Traf1,Syk,Nfkbib,H2-T10,Hspa1b,Nfkb1,Jun,Tyk2,Cd40,Itgal,Ddx58,Akt3,H2-Q7,Cdkn1a,Eif2ak2,Hdac1,H2-T24,Myc,Hspa1a,Ikbkg,Nfkb2,Hspa2,Lyn,Icam1,Tab2,Nfkbie,Spn,Polr2g,Map2k4,H2-T22,Tnfaip3,Fgr,H2-Q4,Relb,Mdm2 |
| 1.118e-07 | -16.01 | Epstein-Barr virus infection | KEGG pathways | ko05169 | 214 | 44 | 7931 | 713 |
Akt3,Hspa1b,Nfkb1,Tyk2,Jun,Stat3,Traf1,Nfkbib,Syk,H2-T10,Traf5,H2-M2,H2-T22,Fgr,Tnfaip3,Mdm2,Spn,Nfkbie,Nfkb2,Icam1,Cdkn1a,H2-Q7,H2-T24,Hdac1,Ddx58,Itgal,Cd40,Cd38,Nfkbia,Traf2,H2-Q6,Il10,Pik3cd,Polr2g,Map2k4,H2-Q4,Relb,Hspa1a,Ikbkg,Hspa2,Lyn,Tab2,Eif2ak2,Myc |
| 1.118e-07 | -16.01 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | 389 | 62 | 15632 | 1249 |
Slc9a1,Rtn2,Flnb,Jag1,Kctd12,Met,Birc3,Abtb2,Hk1,Fscn1,Lhx2,Cdkn1a,Prkar2b,Ptk2,Kif5c,C3,Il13ra1,Stat1,Odc1,Pik3cd,Ier3,Ddx4,Abcb1a,Dusp2,Nat2,4932438A13Rik,Nr4a1,Ifit1bl1,Sqstm1,Agrn,Fos,Pfkfb3,Sdc4,Il15,Ahr,Egr1,H2-Aa,Ifit1bl2,Klf2,Plk2,Fzd5,Atp6v1d,Tfec,Ptger4,Stat3,Micall2,Sat1,Egr2,Kdm5b,Hspa2,Dusp1,Slc16a3,Swap70,Dse,Timp1,Gpsm2,Bcl6,Sgk3,Marcksl1,Tulp3,Arg2,Pigv |
| 1.143e-07 | -15.98 | GSE13547_WT_VS_ZFX_KO_BCELL_UP | MSigDB lists | GSE13547_WT_VS_ZFX_KO_BCELL_UP | 153 | 33 | 15632 | 1249 |
Rhoh,Ddx60,Aim2,Ifih1,Ccnd2,Pttg1,Cyth3,Cd83,Dnase1l3,Cd38,Klf3,Cd200r4,Kif5c,Cd55,Tnfsf4,Nr4a3,Nsmaf,Ier3,Chic2,Rgs1,Sec24a,Chd9,Ccl4,Snn,Ccl5,Abtb2,Cdyl,Plod2,Il10,Slpi,Akt3,Isg20,Rap1gap2 |
| 1.159e-07 | -15.97 | LENAOUR_DENDRITIC_CELL_MATURATION_UP | MSigDB lists | LENAOUR_DENDRITIC_CELL_MATURATION_UP | 104 | 26 | 15632 | 1249 |
Ccl22,Ccnd2,Cd74,Fabp3,Nr1h3,Cd83,Sla,Dnase1l3,Dusp1,Cited2,Irf4,Ctsc,Ccl2,Ccng2,H2-Ab1,Dusp5,Nr4a3,Arf4,Birc3,Gdf15,Sema3c,Cd86,Csf1,Inhba,Mmd,Spint2 |
| 1.168e-07 | -15.96 | GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_DN | 183 | 37 | 15632 | 1249 |
Rasgrp1,Maff,Tifa,Csf1,Rel,Junb,Hsd17b12,Nampt,Pde4b,Hsd17b7,Vrk2,Hcar2,Ldlr,Clcf1,Cxcl10,Chic2,Ptger4,Errfi1,Rin2,Cish,Ccl2,Jun,Ets2,Arhgef3,Msr1,Plekhf2,Ccl12,Mdfic,Olfml3,Olr1,Spred1,Slc25a25,Pim3,Nlrp3,Il1a,Kat2b,Nck1 |
| 1.168e-07 | -15.96 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP | 183 | 37 | 15632 | 1249 |
Icam1,Usp18,P2ry14,Slco3a1,Il4ra,Tmem176b,Rgs3,Samhd1,Cd34,Gclc,Clec4e,Sla,Cd302,Rab32,Casp1,Ccnd1,Fgl2,Ogfrl1,B3gnt5,Pla2g4a,Rai14,Itga9,Ddx4,Ier3,Lyn,Ptk2,Igf2bp2,Cd300lf,Gcnt2,Irf8,Tnfsf14,Cd86,Gem,Plek,Birc3,Myadm,Oas2 |
| 1.168e-07 | -15.96 | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | 183 | 37 | 15632 | 1249 |
Cdkn1a,Fam162a,Clcn7,Tgfbi,Lpar1,Dnajb4,Oas1g,Il13ra1,Spint2,Oas1a,Ccrl2,Pdss1,Alas1,Rtn2,Csf1,Adap2,Fzd5,Tor3a,Hck,Pdgfc,Cd83,Nlrp3,Kmo,Stxbp1,Atf3,Nqo1,Cers6,Rin2,Sdc2,Fchsd2,Slc15a3,Igsf6,Ctsc,Tcf4,Arid5a,Txnrd1,Rab32 |
| 1.169e-07 | -15.96 | AGE-RAGE signaling pathway in diabetic complications | KEGG pathways | ko04933 | 100 | 27 | 7931 | 713 |
Tnf,Stat3,Pik3cd,Akt3,Sele,Jun,Nfkb1,Stat1,Il1b,Vegfc,Icam1,Egr1,Vcam1,Il6,Ccnd1,Nox1,Il1a,Jak2,Ccl12,Col4a2,Ccl2,Stat5a,Prkce,Casp3,Serpine1,Pim1,Edn1 |
| 1.169e-07 | -15.96 | AGE-RAGE signaling pathway in diabetic complications | KEGG pathways | mmu04933 | 100 | 27 | 7931 | 713 |
Pik3cd,Stat3,Tnf,Stat1,Nfkb1,Jun,Sele,Akt3,Ccl12,Il1a,Nox1,Jak2,Vcam1,Il6,Ccnd1,Il1b,Vegfc,Egr1,Icam1,Pim1,Edn1,Serpine1,Casp3,Prkce,Stat5a,Ccl2,Col4a2 |
| 1.183e-07 | -15.95 | BIOCARTA_IL10_PATHWAY | MSigDB lists | BIOCARTA_IL10_PATHWAY | 17 | 10 | 15632 | 1249 |
Tnf,Stat5a,Stat1,Hmox1,Stat2,Il1a,Il10,Stat3,Il6,Stat4 |
| 1.220e-07 | -15.92 | GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP | MSigDB lists | GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP | 44 | 16 | 15632 | 1249 |
Cxcl10,Ptgs2,Prkar2b,Il1b,Serpinb2,Rgs1,Rras2,Il1rn,Cxcl1,Jun,Ccl5,Sod2,Gadd45b,Maff,Inhba,Ddit4 |
| 1.220e-07 | -15.92 | GNF2_CD1D | MSigDB lists | GNF2_CD1D | 44 | 16 | 15632 | 1249 |
Ms4a6d,Tlr2,Tnfaip2,Cd14,Hk3,Hck,Dusp1,Casp1,Tnfrsf1b,Cd86,Fos,Cd302,Igsf6,Fgl2,Nod2,Stx11 |
| 1.220e-07 | -15.92 | GO_STAT_CASCADE | MSigDB lists | GO_STAT_CASCADE | 44 | 16 | 15632 | 1249 |
Clcf1,Il15,Jak2,Socs3,Stat1,Lif,Socs1,Lyn,Stat2,Nmi,Stat3,Stat4,Ifnar1,Ccl12,Stat5a,Osm |
| 1.220e-07 | -15.92 | GO_RESPONSE_TO_EXOGENOUS_DSRNA | MSigDB lists | GO_RESPONSE_TO_EXOGENOUS_DSRNA | 44 | 16 | 15632 | 1249 |
Tlr3,Ripk2,Ddx58,Mul1,Ifna1,Irak3,Ifna2,Zc3hav1,Ifit1bl2,Ifit1bl1,Eif2ak2,Nfkbia,Cav1,Ifna6,Ifna5,Ifnb1 |
| 1.249e-07 | -15.90 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043280 | 121 | 26 | 20694 | 1406 |
Myc,Sirt1,Malt1,Pmaip1,Nlrp3,Uaca,Nlrc4,Stat1,Jak2,Nod1,Cycs,Fas,Apaf1,Ift57,Casp4,Bcl2l11,Tnfsf10,Pml,Casp1,Casp8,S100a8,Syk,Tnfsf15,Fam162a,Mul1,Tnf |
| 1.253e-07 | -15.89 | REACTOME_REGULATION_OF_IFNA_SIGNALING | MSigDB lists | REACTOME_REGULATION_OF_IFNA_SIGNALING | 25 | 12 | 15632 | 1249 |
Ifnb1,Tyk2,Ifna5,Ifna2,Ifna6,Ifna1,Socs1,Usp18,Stat2,Ifnar1,Stat1,Socs3 |
| 1.274e-07 | -15.88 | DORN_ADENOVIRUS_INFECTION_24HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_24HR_DN | 39 | 15 | 15632 | 1249 |
Ier3,Ell2,Egr3,Nfkb2,Cd83,Rnd3,Fubp1,Plk2,Txnrd1,Junb,Nr4a1,Nfkbia,Ifit2,Ccnd1,Il6 |
| 1.274e-07 | -15.88 | GO_CELLULAR_RESPONSE_TO_GLUCOSE_STARVATION | MSigDB lists | GO_CELLULAR_RESPONSE_TO_GLUCOSE_STARVATION | 39 | 15 | 15632 | 1249 |
Ifi207,Ifi214,Ifi204,Upp1,Zc3h12a,Cpeb4,Ifi203,Ifi208,Ifi211,Mndal,Ifi209,Ifi205,Slc2a1,Asns,Ifi213 |
| 1.276e-07 | -15.87 | receptor ligand activity | molecular function | GO:0048018 | 488 | 66 | 20217 | 1400 |
Nampt,Ifna4,Il6,Cxcl10,Saa3,Insl6,Cxcl11,Timp1,Ifna1,Tnf,Ifna2,Ifna5,Pdgfc,Cxcl1,Il12b,Tnfsf8,Il15,Sema3c,Ccl22,Sema4a,Cxcl3,Ccl5,Jag1,Cxcl14,Csf3,Flrt2,Tnfsf9,Ebi3,Edn1,Ccl7,Ccl3,Ccl9,Bmp2,Csf1,Ifnb1,Vegfc,Il18,Osgin2,Tnfsf14,Ccl8,Cdc42ep2,Tnfsf15,Ccl2,Il10,Cxcl9,Flrt3,Cxcl2,Lif,Ccl4,Pf4,Inhba,Cx3cl1,Il27,Kitl,Il1b,Tnfsf4,Ifna6,Tnfsf10,Gdf15,Il1rn,Il1a,Osm,Sema4c,Clcf1,Ccl12,Pdgfb |
| 1.281e-07 | -15.87 | regulation of protein complex assembly | biological process | GO:0043254 | 425 | 59 | 20694 | 1406 |
Palld,Spire1,Tlr2,Prkce,Trim30a,Ahr,Mpp7,Myadm,Rictor,Cav1,Crbn,Lmo4,Tlr6,Dbnl,Hcls1,Csf3,Plek,Hck,Bcl2l11,Src,Cdc42ep2,Whamm,Tmod3,Piezo1,Irgm2,Vasp,Xaf1,G3bp2,Atm,Cyfip1,Mefv,Rhoc,Rac3,Gda,Fscn1,Fas,Icam1,Pmepa1,Tmsb10,Carmil1,Birc2,Dr1,Wars,Cdc42ep4,Met,Ikzf1,Kif9,Evl,H3f3b,Nck1,Eif2ak2,Aim2,Tnf,P2ry12,Fchsd2,Stxbp1,Syk,Ptger4,Mecp2 |
| 1.297e-07 | -15.86 | 25A_SYNTH_2 | prosite domains | PS00833 | 8 | 7 | 13278 | 1037 |
Oasl1,Oas1g,Oas3,Oas1a,Oas1b,Oas2,Oasl2 |
| 1.307e-07 | -15.85 | GO_MYELOID_LEUKOCYTE_ACTIVATION | MSigDB lists | GO_MYELOID_LEUKOCYTE_ACTIVATION | 85 | 23 | 15632 | 1249 |
Jmjd6,Cx3cl1,Rhoh,Relb,Batf,Jun,Syk,Cx3cr1,Prkce,Batf2,Irf4,Nr4a3,Lyn,Pik3cd,Tlr3,Slc7a2,Lcp2,Cd86,Ccl5,Rasgrp1,Tlr1,Stxbp3,Csf1 |
| 1.307e-07 | -15.85 | GO_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | MSigDB lists | GO_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | 85 | 23 | 15632 | 1249 |
Tnfsf14,Swap70,Serpine1,Ccr1,Ccl5,Ccl12,Pla2g7,Cxcl14,Cxcl2,Csf1,Il6,Stap1,Cd74,Lyn,Cx3cl1,Cxcl10,Vegfc,Pf4,Il1b,Cmklr1,Cxcl1,Ccl4,Thbs1 |
| 1.323e-07 | -15.84 | MAPK signaling pathway | KEGG pathways | ko04010 | 252 | 49 | 7931 | 713 |
Map3k6,Daxx,Fas,Dusp5,Tnf,Traf2,Gng12,Rapgef2,Map3k8,Cacnb3,Gadd45b,Ikbkg,Hspa1a,Hspa2,Crkl,Il1b,Tab2,Rac3,Cacna1d,Myc,Casp3,Dusp16,Map2k4,Mapkapk2,Dusp2,Relb,Cd14,Map4k4,Flnb,Dusp6,Pdgfb,Max,Akt3,Hspa1b,Nr4a1,Nfkb1,Jun,Pla2g4a,Nfkb2,Il1a,Dusp8,Gadd45g,Rasgrp1,Pdgfrb,Dusp4,Map2k1,Fos,Rras2,Dusp1 |
| 1.323e-07 | -15.84 | MAPK signaling pathway | KEGG pathways | mmu04010 | 252 | 49 | 7931 | 713 |
Akt3,Max,Pdgfb,Pla2g4a,Jun,Nfkb1,Nr4a1,Hspa1b,Map4k4,Dusp6,Flnb,Fos,Dusp1,Rras2,Dusp4,Pdgfrb,Rasgrp1,Gadd45g,Dusp8,Il1a,Nfkb2,Map2k1,Map3k8,Gadd45b,Cacnb3,Tnf,Dusp5,Fas,Daxx,Map3k6,Rapgef2,Gng12,Traf2,Relb,Dusp2,Mapkapk2,Map2k4,Dusp16,Casp3,Cd14,Tab2,Rac3,Il1b,Hspa2,Crkl,Hspa1a,Ikbkg,Myc,Cacna1d |
| 1.330e-07 | -15.83 | cation binding | molecular function | GO:0043169 | 3560 | 320 | 20217 | 1400 |
Egln3,Lnpk,Pde3b,Rsad2,Pdss1,Pla2g4a,Phyh,Adrb2,B4galt4,Kdm4a,Htr2b,Arg2,Ppm1k,Extl2,Klf2,Car13,Nox1,Cnot4,Dst,Hivep3,Prdm9,Zfp319,Gda,Tab2,Pml,Phf11d,Zc3h12a,P4ha2,Zmynd15,Ptgs2,Endod1,Gch1,Tent4a,Plscr1,Prrg4,Gclc,Cutc,Tet2,Traf2,Hinfp,Zhx2,Gpc1,Hivep2,Cdkn1a,Ago3,Rhou,Vcan,Eno2,Cd69,Gem,Sele,Gna15,Top3a,Mark2,Ifih1,Itga9,Mob3c,Lox,Ciapin1,Tank,Cpd,Jmjd6,Adar,Timp1,Trim14,Rars,Ikbkg,Casz1,Jak2,Prnp,Pgm1,Mefv,Phf11a,Zc3h12c,Mt2,Cdk5r1,Tent2,Lmo4,Xaf1,Dhx58,Dtx3l,Itgal,Ppa1,Acp5,Helz2,Slc25a25,Dtx2,Bcl6,Mob3b,Mmp9,Trmt1l,S100a8,Idi1,Rnf14,Kdm5b,Plekhf2,Rabgef1,Zfp513,Rnf139,Phlpp1,Inpp5b,Mocs1,Ptch1,Cox17,Itga4,Clec4n,Lhx2,Cpeb4,Ldlr,Col11a2,Setdb2,Il1a,Pcgf5,Trim56,Ranbp2,Sat1,Acvr1,Oasl2,Rnf34,Sphk1,Ddx58,Pim1,Klf8,Nr3c1,Aoah,Samhd1,Ltbp2,Itgav,Phf6,Agrn,Zfp36,Zyx,Clec4e,Crbn,Nos2,Foxp4,Pde5a,Trim21,Trafd1,Asap3,Slfn9,Notch1,Sco1,Reps1,Klf6,Ddhd1,Noct,Zfp281,Lpcat2,Tshz1,Rasgrp1,Prkce,Atp11a,Nrp2,Tpm4,Mt1,Morc3,Sirt1,Tax1bp1,Dgka,Sik3,Dnaja2,Nr4a1,Atp13a1,Notch2,Nr1h3,Trim26,Rnf114,Me1,Lrp8,Optn,Rnf19b,Pikfyve,Mmp14,Rnf31,Sod2,Sec24b,Ksr1,Ikzf1,Sap30,Oas3,Trim12a,Gfi1,Cp,Atp2b4,Egr2,Gca,Mmp13,Ext1,Mppe1,Gbe1,Dyrk2,Zswim4,Usp12,Leng9,Cop1,Lcn2,Zcchc2,F10,Antxr1,Zc3hav1,Yju2,Zfp800,Gpd2,Mmp25,Adhfe1,Sesn3,Acvr1b,Lrp4,Adap2,Trim13,Sell,C1ra,Itpr1,Zbtb5,Hmox1,Rnf135,Kdm6b,Trim34a,Mid1,Slfn8,Fam20c,Col27a1,Rcn1,Dck,Inpp1,Riox2,Gbgt1,Slc25a12,Prdm1,Rnf145,Pde1b,Trim36,Mdm2,Asah2,Plod2,Dcp2,Itga5,Aebp2,Oas2,Atp10a,Ppm1l,Phlpp2,Znrf3,Dtnb,Acpp,Nr4a3,Cgas,Trim30a,Nsd3,Sqstm1,Zeb1,Rffl,Traf5,Mthfd2,Lnpep,Txnrd1,Mul1,Ehd1,Birc3,Eya4,Pdlim7,Zup1,Tiparp,Rnf19a,Lap3,Smpdl3b,Tut7,Isg20,Tnfsf10,Tnfaip3,Ubr4,Sec24a,Znrf1,Enpp4,Birc2,Irak3,Pde7b,Col18a1,Map3k6,Lacc1,Micall2,P4ha1,Adgre4,Wdfy1,Cemip2,Cept1,Traf1,Acvrl1,Pfkl,Klf7,Egr3,Parp12,Plod3,Rnf24,Ankib1,Egr1,Ch25h,Thbs1,Snn,Mcm10,Clec4d,Apobec3,Znfx1,Adprm,Htr2a,Ampd3,Rsbn1,Nek6,Klf3,Adam19,Pcx,Cacna1d,Dnaja1,Csrp1,Nt5c3,Jag1,Mgat1,Tcea1,Map3k8 |
| 1.341e-07 | -15.82 | negative regulation of lymphocyte proliferation | biological process | GO:0050672 | 84 | 21 | 20694 | 1406 |
Tarm1,Lyn,Tnfrsf14,Slfn1,H2-Aa,Cd80,Atm,Arg2,Casp3,Il10,Lgals9,Sdc4,Cd274,Fcgr2b,Cd86,Prdm1,Spn,Pde5a,Peli1,H2-Ab1,Prnp |
| 1.341e-07 | -15.82 | negative regulation of mononuclear cell proliferation | biological process | GO:0032945 | 84 | 21 | 20694 | 1406 |
Slfn1,Lyn,Tnfrsf14,Tarm1,Casp3,Arg2,Atm,Cd80,H2-Aa,Cd86,Fcgr2b,Cd274,Sdc4,Lgals9,Il10,Prnp,Peli1,H2-Ab1,Pde5a,Spn,Prdm1 |
| 1.344e-07 | -15.82 | MODULE_123 | MSigDB lists | MODULE_123 | 215 | 41 | 15632 | 1249 |
P2ry14,Etv3,Kdm4a,Tulp3,Stat2,Egr1,Irf2,Atf3,Mxd1,Tle3,Klf7,Batf,Gpsm2,Jun,Ets2,Cited2,Bcl6,Fos,Eif2ak2,Klf6,Mecp2,Egr2,Myc,Nr3c1,Adrb2,Mafg,Fpr1,Rcan1,Irf1,Stat1,Ptger4,Cdkn1a,Lhx2,Nfkb2,Cxcl1,Snapc1,Rel,Nfkb1,Junb,Etv6,Zfp324 |
| 1.345e-07 | -15.82 | activation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0006919 | 77 | 20 | 20694 | 1406 |
Bcl2l11,Casp4,Myc,Apaf1,Ift57,Nlrp3,S100a8,Pml,Casp1,Pmaip1,Casp8,Stat1,Jak2,Nlrc4,Tnf,Fam162a,Cycs,Mul1,Tnfsf15,Nod1 |
| 1.351e-07 | -15.82 | GSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP | MSigDB lists | GSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP | 184 | 37 | 15632 | 1249 |
Tmem184b,Tet2,Plekhf2,Rnf114,N4bp1,Tmem171,Ifih1,Sass6,Pttg1,Dcp2,Stat2,Usp25,Irf2,Mxd1,Angpt1,Ifit1,Enpp4,Crlf3,Zbtb5,Irf7,Marco,Gch1,Tdrd7,Oas1a,Car13,Snx2,Timeless,Cxcl10,Frmd4a,Nr4a3,Dusp5,Dck,Oas1g,Dusp28,Cmpk2,Col27a1,Cflar |
| 1.352e-07 | -15.82 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP | 21 | 11 | 15632 | 1249 |
Dusp6,Cpeb4,Slc4a7,Malt1,Gem,Sgms2,Rcan1,Idi1,Tmem171,Etv5,Stip1 |
| 1.362e-07 | -15.81 | CREL_01 | MSigDB lists | CREL_01 | 239 | 44 | 15632 | 1249 |
Zscan29,Cd69,Zeb1,Med13,Rel,Birc3,Tnfrsf1b,Mob3c,Rbms1,Tnip1,Rap2c,Ier3,Mmp9,Itpkc,S1pr2,Rin2,Mllt6,Ifnb1,Lrch1,Slc44a1,Dock4,Nfkbia,Gadd45b,Zbtb5,Il27,Sdc4,Nfkbid,Tnfsf15,Col11a2,Cd86,Ccl5,Dusp6,Ptges,Nfkb2,Slamf8,Map3k8,Cxcl10,Gng4,Ehd1,Parp8,Relb,Cd74,Icam1,Apba1 |
| 1.365e-07 | -15.81 | BLUM_RESPONSE_TO_SALIRASIB_UP | MSigDB lists | BLUM_RESPONSE_TO_SALIRASIB_UP | 231 | 43 | 15632 | 1249 |
Il6,Phgdh,Acvr1,Ifrd1,Sqstm1,Nfkbia,Rab32,Birc2,Mgat1,Zyx,Serp1,Timp1,Tnfaip3,Relb,Egr1,Usp25,Nupr1,Atf3,Sphk1,Isg20,Cxcl2,Maff,Wars,Rnf14,Nampt,Psat1,Casp4,Ppp1r15a,Asns,Inpp1,Gtpbp2,Gfpt1,Arf4,Cdkn1a,Tcea1,Ell2,Cd55,Mthfd2,Nsmaf,Mafg,Azi2,Chic2,Trib3 |
| 1.378e-07 | -15.80 | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | 169 | 35 | 15632 | 1249 |
Irf7,Ifit3,Tnfsf15,Spint2,Zc3h12a,Parp3,Pim2,Arid5b,Ifit3b,Tgfbi,Phf11d,Mppe1,Nfkb2,Il1rn,Pilrb1,Plcl2,Zhx2,Rnf114,Klf6,Plac8,Hivep2,Phf11b,Oas3,Ifi44,Tapbp,Rhoh,Psme1,Pgs1,Il4ra,Phf11a,Pilrb2,Olr1,Gbp2,Phf11c,Pdgfc |
| 1.378e-07 | -15.80 | GSE3982_DC_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_DN | 169 | 35 | 15632 | 1249 |
Abcc5,Sp140,Syk,Klf3,Ets2,Ppp2r5a,Tlk2,Treml2,Cdkn2d,Tab2,Fpr2,Pfkfb3,Crlf3,Gbp2,Tnfaip3,Tuba4a,Pde4b,Mfap3l,C1rl,Irf7,Rel,Nmi,Zeb1,Spen,Xaf1,Cd69,Syne2,Fam53c,Rnf19b,Mmp25,Mefv,Cflar,Cxcl1,Nfil3,Snn |
| 1.378e-07 | -15.80 | GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN | MSigDB lists | GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN | 169 | 35 | 15632 | 1249 |
Snapc1,Lrrc25,Cxcl1,Mob3c,Dyrk2,Mtmr14,Arid5b,St3gal5,Nrp2,Dusp6,Ccnj,Birc3,Rgl1,Nampt,Plek,Cd86,Ppm1k,Zc3h12c,Nod1,Rnf34,Slc25a25,Zfp319,Aff1,Ncoa7,Myc,Rab9,Rab11fip1,Setdb2,Bnip3,Casp3,Parp8,Mgat1,P2ry13,Ptpn2,Tank |
| 1.407e-07 | -15.78 | intrinsic apoptotic signaling pathway | biological process | GO:0097193 | 154 | 30 | 20694 | 1406 |
Trib3,Pmaip1,Myc,Bnip3,Ier3,Tnfrsf1b,Sirt1,Nupr1,Hmox1,Uaca,Itpr1,Jak2,Casp3,Cdkn1a,Pml,Ddit4,Casp4,Apaf1,Bcl2l11,Plscr1,Dyrk2,Bcl2a1a,Sod2,Bcl2a1d,Ikbke,Tnf,Ifi204,Atm,Ero1l,Bcl2a1b |
| 1.411e-07 | -15.77 | regulation of epithelial cell proliferation | biological process | GO:0050678 | 356 | 52 | 20694 | 1406 |
Itga4,Myc,Ednrb,Zfp36,Kdm5b,Sav1,Ccr3,Notch2,Nod2,Ccl5,Nupr1,Rgcc,Ift57,Acvrl1,Plau,Ccl2,Il10,Intu,Ccl12,Nr4a1,Vegfc,Kdr,Jun,Stat5a,Tnf,Sirt1,Akt3,Notch1,Hmga2,Stat1,Ptch1,Htr2b,Itpr1,Gja1,Errfi1,Cav1,Tnfaip3,Rictor,Ccnd1,Hmox1,Nr4a3,Thbs1,Egr3,Stat3,Adora2b,Bmp2,Il6,Pdgfb,Flt1,Ccnd2,Htra1,Cflar |
| 1.415e-07 | -15.77 | GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_UP | MSigDB lists | GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_UP | 147 | 32 | 15632 | 1249 |
Gbp2,Tap1,Stat2,Psmb10,Intu,Gbp3,Rsad2,Parp14,Rnf24,Psmb9,Znfx1,Dync1h1,Tnf,Nlrc5,Gsdmd,Trafd1,Irf1,Tmem229b,St7,Mmp25,H2-Ab1,Stat1,Il12rb1,Wars,Trim26,Trim21,Ube2l6,Psme2,Slpi,Tap2,Sipa1l1,Psmb8 |
| 1.417e-07 | -15.77 | GSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | 192 | 38 | 15632 | 1249 |
Mafg,Pim1,Smc5,Nfil3,Lrrc8c,Gng12,Gcnt2,Adam19,Sh3bgrl2,Cflar,Serpine1,Nfkb1,Nampt,Hk2,Wars,Ccrl2,Akt3,Tmeff1,Inpp5b,Arl4a,Il4ra,Kmo,Ccnd2,Itga4,Mxd1,Plk3,Me1,Mvp,Enpp4,Fcgr1,Gys1,Fos,Itgav,Psma6,Ift57,Lztfl1,Rai14,Myc |
| 1.417e-07 | -15.77 | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP | 192 | 38 | 15632 | 1249 |
Cacybp,Il10,Birc3,AA467197,Ksr1,Nfkbib,Serpinb9,Mafg,Cxcl10,Naa25,Ebi3,Socs3,Zc3h12a,Rcl1,Il15ra,Bcl2a1a,Cflar,Nfkb2,Homer1,Cd40,Tmem184b,Hmga1,Bcl2a1b,Srm,Bcl2a1d,Irgm2,Fut8,Gbp4,Gbp9,Il6,Phip,Icam1,Cdk5r1,Pgs1,Atf3,Tap1,Pnpt1,Slc16a1 |
| 1.425e-07 | -15.76 | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | MSigDB lists | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | 105 | 26 | 15632 | 1249 |
Aim2,Marcksl1,Lrp8,Nek6,Upp1,Plagl1,Psmb10,Tbc1d1,Gpr84,Abcb1a,Nqo1,Casp1,Slc7a11,Psmb9,Acsl5,Plat,Hmox1,Adora2b,Odc1,Lyn,Phlda1,Jag1,AA467197,Psmb8,Dusp6,Lap3 |
| 1.460e-07 | -15.74 | LINDSTEDT_DENDRITIC_CELL_MATURATION_D | MSigDB lists | LINDSTEDT_DENDRITIC_CELL_MATURATION_D | 73 | 21 | 15632 | 1249 |
Itga5,Ifi214,Ccl22,Tgfbi,Ifi204,Rbms2,Ciita,Dnase1l3,Ifi207,Itgav,Ifi213,Ccr1,Ifi205,Ifi209,Mndal,Igsf6,Ifi208,Egr2,Ifi211,Ifi203,Fgl2 |
| 1.472e-07 | -15.73 | GO_REGULATION_OF_STAT_CASCADE | MSigDB lists | GO_REGULATION_OF_STAT_CASCADE | 140 | 31 | 15632 | 1249 |
Socs1,Cdk5r1,Lif,Ifna2,Notch1,Il15,Crlf3,Ifna1,Ptpn2,Cd40,Flrt3,Ifna5,Ifnb1,Cish,Il6,Stat3,Il12b,Lyn,Il18,Socs3,Ptger4,Socs7,Hcls1,Clcf1,Jak2,Osm,Flrt2,Il10,Cav1,Ccl5,Ifna6 |
| 1.492e-07 | -15.72 | host | cellular component | GO:0018995 | 24 | 11 | 20747 | 1409 |
Irgm2,Iigp1,Gbp8,Axl,Pf4,Gbp2b,Gbp2,Gbp9,Gbp7,Sco1,Gbp3 |
| 1.492e-07 | -15.72 | host cell | cellular component | GO:0043657 | 24 | 11 | 20747 | 1409 |
Sco1,Gbp3,Gbp2,Gbp2b,Gbp9,Gbp7,Gbp8,Iigp1,Axl,Pf4,Irgm2 |
| 1.498e-07 | -15.71 | GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | 256 | 46 | 15632 | 1249 |
H2-Aa,Lcp2,Pde4b,H2-Eb1,Clec4d,Nr4a3,H2-Ab1,Ptprj,Ripk2,Psmb6,Psma6,Dennd1b,Psmb9,Cd40,Src,Cd38,Hck,Myo10,Relb,Tab2,Fgr,Psmb10,Psme1,Malt1,Psme2,Psmb8,Clec4n,Rnf31,Nfkb1,Ikbkg,Actb,Cacnb3,Map2k4,Lyn,Pik3cd,Ptk2,Prkce,Fos,Cyfip1,Psmd10,Jun,Nfkbia,Syk,Fcgr1,Clec4e,Nck1 |
| 1.538e-07 | -15.69 | GO_RESPONSE_TO_PROGESTERONE | MSigDB lists | GO_RESPONSE_TO_PROGESTERONE | 50 | 17 | 15632 | 1249 |
Thbs1,Tspo,Cd38,Socs3,C3,Ptger4,Nr1h3,Sphk1,Socs1,Adrb2,Ccne1,Ccl12,Src,Junb,Fosb,Fos,Cav1 |
| 1.538e-07 | -15.69 | BROWNE_HCMV_INFECTION_4HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_4HR_UP | 50 | 17 | 15632 | 1249 |
Rsad2,Ifit2,Ifit1bl2,Ifit1bl1,Brd2,Sod2,Ifit3,Lcn2,Pcdh7,Thbs1,Tfec,Zc3hav1,Oasl1,Ptgs2,Nr4a3,Ifit3b,Isg15 |
| 1.547e-07 | -15.68 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | 281 | 49 | 15632 | 1249 |
Cnn3,Trim14,Kctd12,Ube2e2,Mmd,Psmb8,Lmo4,Itgal,Ell2,Rcsd1,Rcn1,Dusp2,Lrch1,Ctsc,Pde5a,Syk,Nlrc5,Cnn2,Plac8,Tspan3,Pde3b,Cd34,Angpt1,Spred1,Arrdc4,Sdc1,Hk2,Map4k4,Slc4a7,Pde4b,Bambi,Gcnt2,5430427O19Rik,Gng12,Ubtd2,Fchsd2,Oaf,Phgdh,Nr3c1,Dock10,Ccnd1,Cdyl2,Itpr1,Psmb9,Pbx1,Crlf3,Clcn5,Marcksl1,Sell |
| 1.557e-07 | -15.68 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | 528 | 77 | 15632 | 1249 |
N4bp1,Ifi213,Ifi205,Tank,Serp1,Ifi209,H2-Q6,Swap70,Psmb9,Ly75,Cycs,Stat3,Minpp1,Ccng2,Tapbp,Rbpms,Fgl2,H2-Q7,Cd74,Mvp,Gch1,Myo1b,Tor1aip1,Nmi,H2-Aa,Ifi208,Snx2,Fndc3a,Arid5b,Ak4,Rcan1,Bambi,Tnfsf10,Dek,Vcam1,Glrx,Pgk1,Sec24b,Eif2ak2,Morc3,Cx3cr1,H2-Q4,Cited2,Dnaja1,Bbx,Bnip3,Vcan,Tra2a,4932438A13Rik,Palld,Gbe1,Nxf1,Ifi214,Tspo,Ahr,Aff1,Ifi207,Birc3,Casp4,Mndal,Plod2,Med13,Plscr1,Psme2,Ifi211,Zeb1,Ifi203,Hat1,Stat1,Mtdh,Ifi204,Asf1a,Tmem123,Cflar,Arf4,H3f3b,Igf1r |
| 1.562e-07 | -15.67 | GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_UP | MSigDB lists | GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_UP | 185 | 37 | 15632 | 1249 |
Gca,Tnfsf10,Tlr2,Ifi204,Adora2b,Tgfbi,Mob3b,Cd69,Kctd12,Ifi203,Ifi208,Ifi211,Mndal,Casp8,Dusp6,Slc7a8,Samhd1,Hck,Ifi207,Sla,Ifi214,Prnp,Tulp3,Ch25h,Evl,Cebpd,Rin2,Fgl2,Myc,Ccdc86,Cd302,Ifi209,Ifi205,Arhgef3,Casp1,Syk,Ifi213 |
| 1.562e-07 | -15.67 | GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_UP | MSigDB lists | GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_UP | 185 | 37 | 15632 | 1249 |
Tiparp,Rhof,Plekhf2,Cst7,Itgav,Zswim4,Dusp4,B3gnt5,Ccng2,Lztfl1,Chst11,Pde1b,Egr2,Irs2,Cd74,Egr1,Malt1,Marcksl1,Ier2,Ahr,Fosb,Rel,Myo1b,Cd86,Plek,Hivep3,Mmd,Bcl9,Ddit4,Nr4a3,Il2rg,Gng4,Ptger4,Egr3,Gfi1,Rgs1,Osbpl3 |
| 1.562e-07 | -15.67 | GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | MSigDB lists | GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | 185 | 37 | 15632 | 1249 |
Sh3bgrl2,Trafd1,Fam162a,Ppa1,Oas1g,Ptprj,Endod1,Mafg,Sema4a,Rnf145,Trip13,Parp12,Oas2,Kctd12,Tdrd7,Hivep3,Ccrl2,Oas1a,Ube2e2,Asns,Ahr,Ifit1,Cd38,Nek6,Plk3,Egr2,Phgdh,Dhx58,Ppp1r14b,Srm,Cst7,Cx3cr1,Plac8,Rab32,Eif2ak2,Cd40,Klhl25 |
| 1.562e-07 | -15.67 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_UP | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_UP | 185 | 37 | 15632 | 1249 |
Slc7a2,Lcn2,Rnaset2a,Lcp2,S100a8,Tmem26,Alas1,Pstpip2,Fam111a,Phyh,C3,Glrx,5430427O19Rik,Rnaset2b,Gng12,Gca,Cflar,Serp1,B4galt4,Plod3,Lipe,Mlkl,Prdx5,Ubtd2,Rab9,Rab21,Papss2,Sgms2,Atp11a,Aim2,Irak3,Slc28a2,Olr1,Ppfibp1,Ripk3,Rnd3,F10 |
| 1.562e-07 | -15.67 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN | 185 | 37 | 15632 | 1249 |
Bcl2a1d,B3gnt5,Mdn1,Ikzf1,Fchsd2,Egr2,Ttc39c,Bcl6,Cx3cr1,Gramd1a,Plekha5,Bcl2a1b,Cst7,Casp1,Rgs3,Pde3b,Cyth3,Etv3,Cdk5r1,Mcoln2,Rnf19a,Ube2e2,Inpp5b,Ksr1,Plscr1,Tnfsf14,Ankib1,Map4k4,Tshz1,Pkp4,Jak2,Bcl2a1a,Chd9,Slc29a3,Rcan1,Gpd2,Sema4a |
| 1.562e-07 | -15.67 | GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN | 185 | 37 | 15632 | 1249 |
Oas2,Tnfrsf1b,Sesn3,Rnf14,Lnpep,Eno2,Tor1aip1,Hopx,Tmem123,Jak2,Zhx2,Sp110,Epsti1,St3gal1,Ifi35,Herc6,Pik3cd,Asb13,Nr4a3,Mppe1,Ly75,Dhx58,Rnf114,Morc3,Eno1,Arhgef3,1600014C10Rik,Pde3b,Slc28a2,Tap1,Mark2,Malt1,Mxd1,Evl,Plk3,Nfkbiz,Traf1 |
| 1.562e-07 | -15.67 | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP | 185 | 37 | 15632 | 1249 |
Ociad1,Ppp4r2,Wars,Atm,Igsf9,Ccne1,Clcf1,Notch2,Acsl5,Polr2g,Nfkb2,Slfn9,Igf1r,Lhx2,Cdkn1a,Hmgcs1,Serpinb9,Nr3c1,Slfn8,Tnfsf8,Dusp2,Gbp4,Gbp9,Cox17,Mdm2,Nfkbia,Phldb1,Casp1,Traf5,Tnfrsf14,Rgs3,Phip,Cyth3,Xrn1,Fgr,Arl4a,Rnf135 |
| 1.562e-07 | -15.67 | GSE29618_BCELL_VS_MDC_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DN | 185 | 37 | 15632 | 1249 |
Rab32,Axl,Casp1,Cyfip1,Timp1,Ets2,Tiparp,Eno1,Csf3r,Rab11fip1,Ly75,Cebpd,F11r,Gbe1,Slc30a1,St3gal6,Apaf1,Ahr,Txn1,Map2k1,Pstpip2,Ddit4,Sh3bp4,Spint2,Kctd12,Fzd1,Il13ra1,Rtn1,Trib1,Rcan1,Tgfbi,Ptgs2,Sema4a,Il18,Actb,Rgs1,Glrx |
| 1.562e-07 | -15.67 | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDC_UP | 185 | 37 | 15632 | 1249 |
Smc5,Fam53c,Ttc39b,Ddx4,Slc43a3,Prkx,Gtpbp2,Rbms1,Ppp2r2a,Ap3m2,Hk1,Csrp1,S100a8,Ccr1,Ankib1,Ptch1,Plekha2,Ubr4,Plscr1,Trim21,Stat4,Rars,Fbxo4,Cutc,Pbx1,Ciita,Sgk3,Apaf1,Klf3,Rbbp8,Trip10,Batf2,Ccl2,Nr3c1,Vcan,Glipr2,Nfkbie |
| 1.581e-07 | -15.66 | metal ion binding | molecular function | GO:0046872 | 3462 | 312 | 20217 | 1400 |
Lmo4,Xaf1,Cdk5r1,Mt2,Tent2,Itgal,Ppa1,Dhx58,Dtx3l,Jak2,Casz1,Ikbkg,Trim14,Zc3h12c,Mefv,Phf11a,Prnp,Pgm1,Itga9,Mob3c,Lox,Ifih1,Adar,Timp1,Cpd,Tank,Ciapin1,Jmjd6,Ago3,Rhou,Gpc1,Cdkn1a,Hivep2,Mark2,Top3a,Gna15,Vcan,Cd69,Gem,Sele,Eno2,Plscr1,Tent4a,Gch1,Cutc,Tet2,Traf2,Zhx2,Hinfp,Gclc,Prrg4,Zc3h12a,P4ha2,Zmynd15,Ptgs2,Pml,Phf11d,Endod1,Cnot4,Nox1,Klf2,Ppm1k,Car13,Extl2,Hivep3,Tab2,Gda,Zfp319,Prdm9,Dst,Phyh,Pla2g4a,B4galt4,Pde3b,Rsad2,Egln3,Lnpk,Pdss1,Kdm4a,Arg2,Ddhd1,Reps1,Klf6,Tshz1,Rasgrp1,Zfp281,Lpcat2,Noct,Nos2,Crbn,Trafd1,Asap3,Notch1,Sco1,Slfn9,Foxp4,Trim21,Pde5a,Itgav,Ltbp2,Zfp36,Phf6,Agrn,Clec4e,Zyx,Nr3c1,Sphk1,Ddx58,Pim1,Klf8,Aoah,Samhd1,Trim56,Il1a,Pcgf5,Acvr1,Rnf34,Oasl2,Ranbp2,Cpeb4,Clec4n,Lhx2,Col11a2,Setdb2,Ldlr,Plekhf2,Zfp513,Rabgef1,Kdm5b,Rnf14,Ptch1,Mocs1,Itga4,Cox17,Phlpp1,Rnf139,Inpp5b,Slc25a25,Helz2,Acp5,Dtx2,Bcl6,S100a8,Trmt1l,Idi1,Mob3b,Mmp9,Trim36,Rnf145,Prdm1,Pde1b,Plod2,Itga5,Dcp2,Asah2,Mdm2,Col27a1,Rcn1,Slc25a12,Gbgt1,Dck,Riox2,Inpp1,Hmox1,Rnf135,C1ra,Zbtb5,Itpr1,Slfn8,Fam20c,Mid1,Kdm6b,Trim34a,Yju2,Zc3hav1,Antxr1,F10,Zfp800,Leng9,Zcchc2,Cop1,Lcn2,Usp12,Zswim4,Adap2,Trim13,Lrp4,Acvr1b,Sell,Gpd2,Adhfe1,Mmp25,Gca,Atp2b4,Egr2,Dyrk2,Mppe1,Ext1,Mmp13,Mmp14,Rnf31,Sec24b,Sod2,Pikfyve,Cp,Oas3,Ikzf1,Sap30,Ksr1,Trim12a,Gfi1,Rnf114,Rnf19b,Optn,Lrp8,Me1,Nrp2,Tpm4,Morc3,Mt1,Prkce,Atp11a,Atp13a1,Nr4a1,Dnaja2,Sik3,Trim26,Nr1h3,Notch2,Tax1bp1,Sirt1,Dgka,Cacna1d,Dnaja1,Csrp1,Nek6,Klf3,Pcx,Adam19,Map3k8,Tcea1,Jag1,Nt5c3,Mgat1,Snn,Egr1,Thbs1,Ch25h,Rsbn1,Ampd3,Apobec3,Clec4d,Mcm10,Adprm,Znfx1,Plod3,Ankib1,Rnf24,P4ha1,Micall2,Lacc1,Map3k6,Traf1,Acvrl1,Cemip2,Cept1,Parp12,Pfkl,Egr3,Klf7,Adgre4,Wdfy1,Isg20,Tut7,Tnfaip3,Tnfsf10,Lap3,Rnf19a,Smpdl3b,Pde7b,Col18a1,Sec24a,Ubr4,Birc2,Irak3,Znrf1,Enpp4,Birc3,Zup1,Eya4,Pdlim7,Txnrd1,Mul1,Ehd1,Tiparp,Cgas,Nsd3,Trim30a,Nr4a3,Mthfd2,Lnpep,Rffl,Traf5,Sqstm1,Zeb1,Ppm1l,Phlpp2,Znrf3,Aebp2,Oas2,Atp10a,Dtnb |
| 1.623e-07 | -15.63 | double-stranded DNA binding | molecular function | GO:0003690 | 1003 | 113 | 20217 | 1400 |
Kat2b,Egr1,Atf3,Irf2,Notch1,Foxp4,Mcm10,Mndal,Klf3,Klf6,Tal2,Ifi209,Zfp281,Plagl1,Nr3c1,Ddx60,Ddx58,Junb,Klf8,Egr3,Klf7,Ifi204,Ifi213,Nfil3,Jun,Ets2,Nfxl1,Lhx2,Rbbp8,Batf,Pou2f2,Nfkb2,Pcgf5,Hmga1,Ifi207,Ifi208,Stat4,Batf2,Hif1a,Arid5b,Jdp2,Aebp2,H3f3b,Jarid2,Bcl6,Mafg,Ifi214,Cgas,Dach1,Mycl,Nr4a3,Kdm5b,Fos,Zeb1,Mxd1,Cebpd,Ifi211,Aff1,Hdac1,Lmo4,Irf7,Prdm1,Mafk,Mcm9,Fosb,Nfkb1,Pbx1,Ahr,Irf1,Hivep2,Aim2,Stat2,Eno1,Mcm6,Stat1,Etv3,Psip1,Zbtb5,Myc,Rfx5,Maff,Adar,Kdm6b,Stat3,Ifi205,Hhex,Tcf4,Irf8,Zbp1,Stat5a,Fubp1,Hmga2,Spic,Ikzf1,Ifi203,Rel,Egr2,Relb,Irf4,Hinfp,Etv5,Ier2,Max,Nr4a1,Nr1h3,Nlrc5,Sirt1,Bcor,Tfec,Sp140,Prdm9,Mecp2,Etv6 |
| 1.631e-07 | -15.63 | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 193 | 38 | 15632 | 1249 |
Cyfip1,Acpp,Ehd1,Abcc5,Cox17,Treml2,Kdm5b,Ccng2,Cpd,Calcrl,Il1a,Dmxl2,Pigv,P2ry14,Socs1,Hck,Col4a2,Plekha2,Birc3,Dach1,Mmd,Trim56,Stx11,Egln3,Cd69,Rap1gap2,Spint2,Pstpip2,Zeb1,Ampd3,Alas1,Ebi3,Igf1r,Hcar2,Socs7,Znrf1,Gtpbp2,Lrp11 |
| 1.631e-07 | -15.63 | GO_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | MSigDB lists | GO_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 193 | 38 | 15632 | 1249 |
Il1a,Mul1,Tlr6,Daxx,Mdfic,Nod1,Prdx1,Bmp2,Traf2,Dnaja1,Eif2ak2,Gadd45b,Map3k6,Ezr,Hsph1,Tnf,Syk,Phlpp1,Nod2,Mid1,Gadd45g,Edn1,Dbnl,Myc,Aida,Lyn,Nox1,Sema4c,Tlr3,Tlr9,Zc3h12a,Ripk2,Igf1r,Il1b,Fzd5,Map2k1,Map4k4,Rasgrp1 |
| 1.661e-07 | -15.61 | catalytic activity, acting on a protein | molecular function | GO:0140096 | 2152 | 209 | 20217 | 1400 |
Mmp9,Dusp1,Vrk2,Jarid2,Fgl2,Psma6,Phlpp1,Rnf139,Kdm5b,Rnf14,Plau,Casp8,Rabgef1,Usp53,Setdb2,Irak2,Hp,Ranbp2,Rnf34,Acvr1,Ubash3b,Ube2e1,Akt3,Trim56,Scyl2,Htra1,Map4k4,Tpst1,Pdk3,Pim1,Casp2,Uba7,Usp31,Stk40,Casp3,Ptprj,Trim12c,Flt1,Fbxo4,Ccnd2,Trim21,Ppp2r2a,Fignl2,Ube2f,Parp14,Ptpn2,Rhbdf2,Kdm4a,Ube2e2,Egln3,Usp42,Cflar,Prdm9,Med21,Psmb10,Ppm1k,Ccnj,Cnot4,Kmt5a,Acp2,P4ha2,Zc3h12a,Usp25,Trib1,Ccnd1,Vcpip1,Grk3,Traf2,Pim3,Bfar,Ppp2r1b,Mark2,Cdkn1a,Pim2,Jmjd6,Tank,Cpd,Syk,Ripk3,Prkx,Mapkapk2,Pdgfrb,Eif2ak2,Lox,Dusp4,Hk1,Hdac1,Parp11,Fgr,Map2k4,Met,Jak2,Dtx3l,Hck,Mmd,Trib3,Dusp2,Tyk2,Kdr,Znrf3,Ccne1,Phlpp2,Ppm1l,Ripk2,Rffl,Lnpep,Arel1,Trim30a,Nsd3,Psmb9,Tiparp,Dusp6,Mul1,Ube2l6,Zup1,Eya4,Birc3,Irak3,Birc2,Znrf1,Peli1,Ubr4,Herc6,Dusp8,Tlk2,Lap3,Rnf19a,Tnfaip3,Parp10,Ctsc,Parp12,Parp3,Acvrl1,Casp1,Map3k6,Ikbke,P4ha1,Ppp2r5a,Plk3,Rnf24,Prag1,Ankib1,Dusp16,Plod3,Dusp5,Ccng2,Map2k1,Parp8,Mgat1,Ccl5,Map3k8,Usp18,Adam19,Nek6,Malt1,Mlkl,Katna1,Sirt1,Plk2,Sik3,Prkce,Lyn,Nrp2,Otud1,Rnf19b,Dusp28,C1rl,Bcor,Trim12a,Sap30,Ksr1,Casp7,Mmp14,Rnf31,Mmp13,Psmb8,Dyrk2,Ptk2,Egr2,Mmp25,Trim13,Acvr1b,Cop1,Usp12,Sgk3,Adgb,Usp35,Ero1l,Mtmr14,F10,Igf1r,Kdm6b,Fam20c,Src,C1ra,Rnf135,Sla,Dusp14,Axl,Uchl1,Casp4,Fut8,Mdm2,Plod2,Psmb6,Rnf145,Atm,Plat,Trim36 |
| 1.663e-07 | -15.61 | regulation of tube diameter | biological process | GO:0035296 | 172 | 32 | 20694 | 1406 |
Pdgfb,Kdr,Hif1a,Ptafr,Sod2,Cx3cl1,Ptgs2,Tnf,P2ry2,Adora2a,Cd38,Adrb2,Dusp5,Adora2b,Gch1,Map2k1,Htr2b,Gja1,Edn1,Cav1,Kat2b,Ahr,Icam1,Dock4,Pde5a,Plod3,Gclm,Htr2a,Ednrb,Sirt1,Ptk2,Gclc |
| 1.663e-07 | -15.61 | regulation of blood vessel diameter | biological process | GO:0097746 | 172 | 32 | 20694 | 1406 |
Gch1,Map2k1,Adora2b,Dusp5,Cd38,Adrb2,Ptgs2,Cx3cl1,Tnf,P2ry2,Adora2a,Sod2,Kdr,Hif1a,Ptafr,Pdgfb,Gclc,Ptk2,Ednrb,Sirt1,Pde5a,Plod3,Gclm,Htr2a,Ahr,Dock4,Icam1,Cav1,Kat2b,Gja1,Htr2b,Edn1 |
| 1.712e-07 | -15.58 | E2F1_UP.V1_DN | MSigDB lists | E2F1_UP.V1_DN | 178 | 36 | 15632 | 1249 |
Nfkb1,Klf2,Plk2,Slpi,Phlda1,Ampd3,Csf1,Zc3h12a,C3,Traf3ip2,Dtx2,Hmgcs1,Il18,Trib3,Ptgs2,Ralgds,Plat,Notch2,Ccl12,Klf3,Ifit2,Lipe,Tank,Bcl6,Tcf4,Rab9,Myc,Stat3,Pla2g4a,Mdn1,Ccng2,Vcan,Nfkbiz,Fas,Ccnd2,Gbp2 |
| 1.717e-07 | -15.58 | symbiont-containing vacuole membrane | cellular component | GO:0020005 | 12 | 8 | 20747 | 1409 |
Pf4,Gbp3,Iigp1,Gbp8,Gbp7,Gbp9,Gbp2b,Gbp2 |
| 1.724e-07 | -15.57 | UDAYAKUMAR_MED1_TARGETS_DN | MSigDB lists | UDAYAKUMAR_MED1_TARGETS_DN | 209 | 40 | 15632 | 1249 |
Pilrb2,Tle3,Rhoc,Fas,Atf3,Mapkapk2,Palld,Upp1,Arl4a,Sat1,Mdm2,Phlpp1,Ifrd1,Rbpms,Axl,Ehd1,P4ha2,Gadd45b,Ets2,Cited2,Pilrb1,Pcdh7,Bambi,Tnfaip2,Trafd1,Cdkn1a,Fam53c,Hmox1,Dusp5,Rcan1,Trib1,Pim1,Arid5b,St7,Rtn2,Abtb2,Junb,Brd2,Plk2,Fubp1 |
| 1.731e-07 | -15.57 | GSE10325_CD4_TCELL_VS_BCELL_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_BCELL_DN | 163 | 34 | 15632 | 1249 |
Ciita,Cd83,Rras2,Aim2,Hhex,Cd180,Kmo,Fcgr2b,Irf4,Stap1,Rhoq,Fchsd2,Slc15a3,Plac8,Plekhf2,Sp140,Syk,Swap70,Tspan3,Jun,Rhbdf2,Tcf4,Cd40,Adam19,Clic4,H2-Ab1,Cd200,Lyn,Timeless,Slc2a6,H2-Aa,4930523C07Rik,Irf8,Sipa1l1 |
| 1.732e-07 | -15.57 | vesicle | cellular component | GO:0031982 | 1943 | 189 | 20747 | 1409 |
Phlda1,Clcn7,Ccr3,Chmp4b,Dmxl2,Stx11,Esd,Sh3bp4,Pml,Agtrap,Kif9,Rab20,Vasn,Clic4,Ldlr,Nox1,Myo1b,Pde4b,Tlr3,H2-Ab1,Ifnar1,Fcho2,Src,Atm,Rab11fip1,Dgkh,Marcksl1,Chic2,Gch1,Vps54,Mefv,Tmem123,Gbp9,Dtx3l,Slc29a3,Znrf1,Gbp3,H2-Eb1,Lpar1,Il1b,Rubcnl,Ccl2,Scyl2,Fcgr2b,Map2k1,Aftph,Asah2,Rap2c,Zc3hav1,Traf2,Fnbp1l,Optn,Pdgfrb,Sema4c,Hap1,Ifitm1,Plat,Treml4,Arrdc4,Gbp8,Stoml1,Flnb,Snx10,Snx2,Cd38,Zyx,Dst,Ppfia3,Ociad1,Rab32,Lipg,Sla,F11r,Stxbp3,Slc4a7,Thbs1,Fas,Itpr1,Pdpn,Bmp2,Il15ra,Cd74,Psd,Dennd6b,Pf4,Calcrl,Tmem67,Lcn2,Gbp2,Pikfyve,Itga5,Htr2a,Cst7,Sqstm1,Gja1,Trim36,Notch1,Spire1,Abcc4,Slc31a1,Tlr6,Stxbp1,Cdc42ep2,Rab9,Tlr1,Cd86,Slc39a4,Trim21,Slc31a2,Nck1,Rab10,Hilpda,Cd274,Tlr9,Ezr,Edn1,Slc30a4,Vezt,Dennd1b,P2ry2,Cav1,Slc48a1,Irgm1,Fndc3a,Nod2,Rab21,Icam1,Plekhf2,Aoah,Msr1,Acpp,Adrb2,Evl,Gbgt1,Kif3c,Inpp5b,Ripk2,Syk,Flt1,Tnf,Wdfy1,Lnpep,Mmp14,Sec24b,Itga4,Spred1,Cd164,Mcoln2,Pmepa1,Gbp7,Stx6,Il1rn,Hck,Prdx5,Cdc42ep4,Gpc1,Ap3b1,Sgk3,Pla2g4a,Apba1,Rapgef2,Rabgef1,Clcn5,Kdr,Gpr18,Tlr2,Atp11a,Carmil1,Dbnl,Sphk1,Serpine1,Whamm,Gbp2b,Samd9l,Atp11b,Sec24a,Micall2,Mitd1,Fzd5,Vcam1,Nos2,Rffl,Acp2,Socs1,Srgn,Ehd1,Fchsd2,Slc2a1,Ap3m2 |
| 1.782e-07 | -15.54 | tumor necrosis factor receptor superfamily binding | molecular function | GO:0032813 | 45 | 15 | 20217 | 1400 |
Tnfsf8,Cflar,Traf1,Tnfsf10,Casp8,Stat1,Tnfsf14,Nsmaf,Tnfsf15,Tnfsf9,Casp3,Traf2,Tnf,Tnfsf4,Traf5 |
| 1.787e-07 | -15.54 | TSAI_DNAJB4_TARGETS_UP | MSigDB lists | TSAI_DNAJB4_TARGETS_UP | 14 | 9 | 15632 | 1249 |
Cdkn1a,Ccng2,Ifit3b,Oas3,Isg15,Ifit3,Stat1,Ifit1bl2,Ifit1bl1 |
| 1.787e-07 | -15.54 | cellular component organization or biogenesis | biological process | GO:0071840 | 5181 | 434 | 20694 | 1406 |
Sgcb,Tomm70a,Mdn1,Zc3h12a,Trip10,Scarf1,Chmp4b,Mx1,Marco,Top3a,Sbds,Casp4,Tgfbi,Jarid2,Ccne1,Micall2,Hap1,Rrs1,Smg7,Rilpl1,Mthfr,Traf2,Znfx1,Tifa,Lrp4,Mul1,Tmod3,Dtx3l,Itga4,Gclm,Irf4,Ep400,Mmp14,Rhoc,Trip13,Stau1,Sema4c,Edn1,Frmd6,Rubcnl,Fas,Nsd3,Pkp4,Fmnl2,Asf1a,Rab21,Cnp,Cx3cr1,Intu,Cenpe,Hspa1a,Lnpk,Fchsd2,Slc2a1,Sirt1,Mmp9,Kctd12,Sqstm1,Dbnl,Tagln,Riox2,Itpr1,Samd9l,F11r,Klf7,Cav1,Spire1,Myadm,Rapgef2,Plscr1,Marf1,Ddx4,Cyfip1,Syne2,Rpgrip1l,Max,Col27a1,Lipg,Fscn1,P4ha1,Parp3,Gclc,Lpcat2,Rbl1,Psd,Pfkl,Nlgn2,Dync1h1,Dr1,Jmjd6,Kat2b,Uchl1,Slc16a1,Icam1,Pstpip2,Angpt1,Ikzf1,Kif9,Acpp,Rasgrp1,Tmem123,Ccl12,Tpx2,Stxbp1,Tcf4,Jun,Pcgf5,Daxx,Tuba4a,Tnf,Plk3,Rgs14,Akt3,Pdss1,Nlrp3,Rap1gap2,Jak2,Rictor,Tnfaip3,Hmgn3,Dek,Nr3c1,Cox17,Sass6,Treml4,Bcl2l11,Snx10,Map2k1,Dock10,Eif4g2,Marcks,Ube2e1,Kcna3,Wdr43,Gpc1,Pdgfrb,Fzd5,Ptk2,Rab3ip,Rac3,Kdm5b,Etv6,S1pr2,Ifrd1,Hspa2,Tor1aip1,Antxr1,Dgkh,Rhoq,Stx6,Sipa1l1,Igsf9,Col18a1,Nupr1,Arrdc4,Evl,Slamf8,Stard5,Noc4l,Ccl2,D1Ertd622e,Birc3,Sco1,Arid4a,Tnc,Kif5c,Ascc3,Aebp2,Pnpt1,Pdpn,Lrrc8c,Btg2,Hsd17b12,Mlkl,Tet2,Pmaip1,Pim3,Diaph2,Acp2,Keap1,Prkce,Cdk5r1,Nrp2,Lhx2,Plek,Cep350,Nfkb2,G3bp2,Mcm9,Phgdh,Lox,Ttc39c,Cnn2,Bnip3,Psmb10,Ccdc88b,Agrn,Daam1,Clic4,Brd2,Tmem67,Stxbp3,Mtfr2,Srgn,Nck1,Fnbp1l,Gpr35,Denr,Spata13,Pikfyve,Abcc1,Sdc4,Katna1,Etv5,Sik3,Arhgap26,Spaca6,P2ry12,Pid1,Notch1,Rhoh,Vcpip1,Flnb,Znrf1,Mx2,Hmox1,Tlr2,Rnd3,Map4k4,Csf3,Myo1b,Mitd1,Cdc42ep2,Stx11,Tapbpl,Tlk2,Atp10a,Scn1b,Mcmbp,Irgm2,Smc5,Slc12a9,Nectin2,Clic5,Homer1,Xrn1,Tsku,Trim21,Pla2g7,Nod2,Flrt2,Carmil1,Tmsb10,Tap2,Lrp8,Hdac1,Cdc42ep4,Adgrg6,Xkr8,Mcoln2,Abcb1a,Mmp13,Ehd1,Adora2a,Arf4,Csrp1,Ier3,Axl,Gpsm2,Txnrd1,Cnn3,Hhex,Rab32,Ptch1,Atp11a,Lyn,Parp11,Ahr,Ltbp2,Cdyl,Coa5,Whamm,Isg20,Adgrl2,Tpm4,Nes,Atm,Abr,Cox18,Ift22,Sec24b,Malt1,Actb,Gsdmd,C3,Cd74,Igf1r,Psip1,Nox1,Cutc,Phip,Fignl2,Msr1,Ccl5,Noct,Col4a2,Rab20,Pml,Brwd3,Ciapin1,Zyx,Pim2,Ago3,Eya4,Bcorl1,Sod2,Fcho2,Trim36,Snx2,Dnase1l3,Abcc4,Optn,Apba1,Swap70,Mcm6,Crkl,Hat1,Nlrc4,Spint2,Bcor,Flrt3,Cycs,Ripk3,Adar,Mpp7,Sema3c,Stat3,Src,Ggct,Lst1,Lcn2,Kcnj2,Sec24a,Tapbp,Hcls1,Pdgfb,Dst,Ero1l,Lpar1,Ikbke,Vps54,Myc,Rsbn1,Plagl2,Klf2,Birc2,Ntng2,Triobp,Spry2,Apaf1,Pf4,Slc9a1,Fcgr1,Ezr,Ddit4,Sdc2,Phactr4,Mecp2,Cenpj,Hopx,Rhou,Ap3b1,Mdm2,Palld,Pdgfc,Pttg1,Hmga2,Hk2,Rhof,Itgav,Gja1,Dnaaf3,Rtp4,Casp3,Nr4a3,Psmd10,Cd34,Prdm9,Cacnb3,Thbs1,Plk2,Fbxo4,Chd9,Prnp,Sema4a,Ddhd1,Gem,Samhd1,Kdm4a,Il6,Itga5,Atp11b,Cflar,Sap30,Vasp,Mmp25,Plod3,Bcl6,Pdlim7,Tor1aip2,Ppp1r15a,Plod2,Mark2,Rnd1,Kdm6b,Kmt5a,Ext1,Rab10,Ift57,Me1,H3f3b,Rcl1,Met,Irgm1,Fcgr2b,Gch1,Col11a2,Gfpt1,Plaat3,Egr2,Setdb2,Kdr,Cx3cl1,Atp6v1d |
| 1.788e-07 | -15.54 | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP | MSigDB lists | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP | 80 | 22 | 15632 | 1249 |
Chst11,Ppp2r3a,Ifi203,Ifi211,St3gal5,Il6,Ifi44,Ifi208,Asns,Ifi209,Mndal,Ifi205,Ifi213,Igf1r,Ifi207,Cdc42ep2,Ifi204,Ifi214,Nr4a3,Casp7,Hmox1,Filip1l |
| 1.800e-07 | -15.53 | GO_REGULATION_OF_TRANSPORT | MSigDB lists | GO_REGULATION_OF_TRANSPORT | 1651 | 188 | 15632 | 1249 |
Pde4b,Ccl5,Inhba,Tbc1d13,Fzd1,Tlr3,Trib3,Sec24a,Tnf,Traf2,Rhbdf2,Serp1,Rab21,Nfkbie,Sele,Hspa2,Gpr68,Rsad2,Parp10,Rnf139,Cd74,Sgk3,Lipg,Cd14,Hvcn1,S100a8,Nfkb1,Casp8,Slc9a1,Nfkbib,Rhou,Lyn,Clcn7,Jak2,Ccl4,Cdkn1a,Lrrc8c,Syk,Dnaja1,Stap1,Stxbp1,Sdc1,Irs2,Mul1,Slc30a1,Slc16a1,Slc31a2,Txn1,Tlr1,Scn1b,G3bp2,Hap1,Hk2,Scyl2,Clec5a,Ptgs2,Il12b,Glrx,Hcar2,Axl,Ifnar1,Casp1,Rab9,Rhoq,Nfkbil1,Pml,Icam1,Fgr,Sphk1,Clcn5,Clic5,Clec4n,Rnf31,Il10,Tnfsf14,P2ry2,Tnfsf4,Tlr2,Hcls1,Stard7,Nfkbia,Ccl12,Il6,Tlr6,Prnp,Il4ra,Prdx1,Ccr1,H2-Eb1,Gja1,Cd274,Fzd5,Map2k1,Osm,Pdgfrb,Serpine1,Stxbp3,Mmp13,Hmox1,Adora2b,Nr4a3,Il18,Il1b,Htr2b,Keap1,Homer1,Micall2,Rab11fip1,Rbpms,Plk3,Aim2,Cd38,Plagl2,Ednrb,Pid1,Cav1,Nos2,Rtn2,Tlr9,C3,Mmp9,Cacnb3,Crbn,Gsdmd,Itgav,Pla2g4a,Ubash3b,Cdk5r1,Nr1h3,Cx3cl1,Cd34,Sdc4,Pim3,Tspo,Clec4e,Pdgfb,Csf3,Ptger4,Zc3h12a,Kcna3,Cxcl10,Ptafr,Bambi,Thbs1,Clic4,Vegfc,Sec24b,Src,Ehd1,Itpr1,P2ry12,Slc2a1,Cd40,Tbc1d1,Kdm5b,Mdm2,Lif,Il1a,Hif1a,Ddx58,Socs1,Notch1,Mdfic,Hck,Rabgef1,Ptch1,Rims3,Sirt1,Rasgrp1,Nox1,Dyrk2,Adrb2,Cacna1d,Pfkl,Nlgn2,Ezr,Bcl2l11,Psmd10,Edn1,Kcnj2,Prkce,Nod2,Abr,Nlrp3,Htr2a,Atp2b4,Tnfrsf14,Angpt1 |
| 1.802e-07 | -15.53 | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | MSigDB lists | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | 186 | 37 | 15632 | 1249 |
Vcam1,Cmklr1,Itga9,Slamf8,Fcho2,Lpar1,Cxcl10,Il18,C3,Mmp9,Tmem176a,Kctd12,Antxr1,Flrt2,Rgl1,Gja1,Spred1,Irak3,Rnd3,Col4a2,Papss2,Nr1h3,Tmem176b,Rbpms,Samd9l,Acvrl1,C1ra,Tnc,Ctsc,Cp,Rai14,Pdpn,Cyfip1,P2ry13,Dock4,Tagln,Ccl12 |
| 1.802e-07 | -15.53 | GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP | MSigDB lists | GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP | 186 | 37 | 15632 | 1249 |
Morc3,Gramd1a,Cnn2,Klf6,Slc2a1,Cish,Cpd,Prdx5,Egr1,Pml,Icam1,Hif1a,Kat2b,Sphk1,Myd88,Rab3ip,Plagl2,Mvp,Txn1,P4ha1,Tshz1,Gja1,Hk1,Casp8,Atp6v1d,Vps54,Phlda1,Inhba,Dgka,Maff,Fndc3a,Ldha,Mob3b,Ier3,Ddx4,Glrx,Lrrc8c |
| 1.802e-07 | -15.53 | GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_DN | MSigDB lists | GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_DN | 186 | 37 | 15632 | 1249 |
Pigv,Malt1,Atf3,Pml,Slc28a2,Tap1,Traf5,Ciita,1600014C10Rik,Cd40,Ezr,Plac8,Klf3,Rnf114,Chst11,Rhoq,Pik3cd,Gpd2,Ifit3b,Socs3,Dusp5,Cd82,Gna15,Ifit3,Lcp2,Casp8,Irf7,Map2k1,Pde4b,Sesn3,Ikbkg,Tmem26,Ccrl2,Trim56,Oas2,Btg2,Trim21 |
| 1.802e-07 | -15.53 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_UP | 186 | 37 | 15632 | 1249 |
Cxcl2,Phlda1,Pdgfb,Csf1,Gem,Lmo4,Sema3c,Zc3h12c,Gna15,Dusp6,Junb,Dach1,Slc7a8,Glrx,Plaur,Tnip1,Bcl2a1a,Gtpbp2,Cxcl1,Ccng2,Bcl2a1d,Ifrd1,Mdm2,Casp3,Cited2,Bcl6,Fos,Tagln,Bcl2a1b,Dusp1,Nr4a1,Tnf,Slc25a25,Il1a,Trim13,Mapkapk2,Nfkbiz |
| 1.802e-07 | -15.53 | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP | 186 | 37 | 15632 | 1249 |
Rbbp8,Tiparp,Tcf4,Parp8,Casp1,Insl6,Cnot4,Mecp2,B3gnt5,Tapbp,Dhx58,Rsad2,Nr3c1,Stap1,Gbp9,Slc44a1,Gbp4,Ly75,Ddx60,Slc30a4,Mdfic,Gnb4,Nampt,Uba7,Rab10,Tifa,Rcn1,Ms4a6d,Irf1,St7,Azi2,Ptger4,Uchl1,Dio2,Nlgn2,Cdkn1a,Frmd6 |
| 1.817e-07 | -15.52 | regulation of T-helper cell differentiation | biological process | GO:0045622 | 40 | 14 | 20694 | 1406 |
Malt1,Zc3h12a,Irf1,Il18,Bcl6,Il27,Nlrp3,Tnfsf4,Il6,Nfkbiz,Ripk2,Hlx,Nfkbid,Il4ra |
| 1.830e-07 | -15.51 | Interferon alpha/beta signaling | REACTOME pathways | R-MMU-909733 | 28 | 13 | 8608 | 757 |
Ifna2,Socs1,Ifna1,Ifna6,Stat1,Ifna4,Ifnb1,Stat2,Ifnar1,Socs3,Tyk2,Ifna5,Usp18 |
| 1.866e-07 | -15.49 | TGFB_UP.V1_UP | MSigDB lists | TGFB_UP.V1_UP | 171 | 35 | 15632 | 1249 |
Edn1,Chst11,Phldb1,Tagln,Dpy19l1,Spsb1,Gadd45b,Jun,Ets2,Lipg,Pfkfb3,Tle3,Klf7,Bcor,Lif,Hlx,Atf3,Sphk1,Jmjd6,Pdgfb,Rapgef2,Mmd,Ltbp2,Abtb2,Junb,Clcf1,Pmepa1,Itga5,Ell2,Dyrk2,Smox,Rnf19b,Kdm6b,Pik3cd,Trib1 |
| 1.869e-07 | -15.49 | negative regulation of transcription, DNA-templated | biological process | GO:0045892 | 1165 | 125 | 20694 | 1406 |
Btg2,Mdm2,Rfx5,Klf3,Etv3,Sirt1,Trib3,Irf8,Il1b,Hmga2,Hhex,Sqstm1,Ifi205,Ptch1,Klf7,Zmynd15,Cav1,Relb,Nfkb1,Ccnd1,Ahr,Ifi209,Nr4a3,Psmd10,Cdk5r1,Cd38,Timeless,Mier3,Nmral1,Dusp5,Rel,Zbtb5,Bmp2,Nfil3,Kdm4a,Hif1a,Ciita,Sap30,Ahrr,Ifi213,Max,Bcl6,Ifi214,Arid5b,Ednrb,Ppp1r15a,Junb,Txn1,Gclc,Mtdh,Kmt5a,Rbl1,Dnajb4,Eno1,Dr1,Notch2,Zhx2,Jdp2,Egr1,Mxd1,Nck1,Zfp281,Prdm1,Mafk,Met,Ikzf1,Ifi207,Phf6,Atf3,Pml,Arid5a,Cited2,Jun,Tcf4,Fzd1,Plk3,Tnf,Mdfic,Daxx,Ifi204,Ifi211,Gfi1,Mndal,Notch1,Hat1,Bcor,Prdx5,Klf8,Foxp4,Nr3c1,Src,Ccne1,Ifi203,Jarid2,Hcls1,Nfkbie,Pdgfb,Parp9,Ifi208,Znfx1,Gbp4,Myc,Cebpd,Ptpn2,Zfp36,Kdm5b,Zeb1,Etv6,Nr1h3,Spen,Klf2,Edn1,Nsd3,Hdac1,Irf1,Dach1,Ezr,Hinfp,Tnfsf4,Mecp2,Ets2,Arid4a,Aebp2,Hopx,Slfn1 |
| 1.884e-07 | -15.48 | SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM | MSigDB lists | SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM | 35 | 14 | 15632 | 1249 |
Cflar,Gfpt1,Slamf7,Tnfaip3,Nfil3,Prdm1,Pim2,Dusp5,Ell2,Irf4,Casp3,Isg20,Myc,P4ha1 |
| 1.884e-07 | -15.48 | BIOCARTA_TOLL_PATHWAY | MSigDB lists | BIOCARTA_TOLL_PATHWAY | 35 | 14 | 15632 | 1249 |
Tlr3,Tlr9,Tlr6,Tab2,Tlr2,Map2k4,Myd88,Cd14,Nfkbia,Eif2ak2,Nfkb1,Ikbkg,Fos,Jun |
| 1.884e-07 | -15.48 | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN | MSigDB lists | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN | 35 | 14 | 15632 | 1249 |
Cd83,Ciita,Ahr,Rhoh,Hhex,Il4ra,Nfkbie,Mmd,Gch1,Nfkb1,Irf8,Itpr1,Rel,Gpr18 |
| 1.884e-07 | -15.48 | GNF2_FOS | MSigDB lists | GNF2_FOS | 35 | 14 | 15632 | 1249 |
Zfp36,Stx11,Fgl2,Nod2,Vcan,Dusp6,Nfkbia,Dusp1,Cd302,Fos,Hk3,Ier2,Nlrp3,Ms4a6d |
| 1.887e-07 | -15.48 | GU_PDEF_TARGETS_UP | MSigDB lists | GU_PDEF_TARGETS_UP | 74 | 21 | 15632 | 1249 |
Ptk2,Itga5,Mapkapk2,Rac3,Tgfbi,Sdc1,Hif1a,Pik3cd,Mapkbp1,Col4a2,Bmp2,Map4k4,Tcf4,Dock4,Serpine1,Tnc,Zeb1,Hdac1,Sdc2,Fzd1,Dock10 |
| 1.887e-07 | -15.48 | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | 74 | 21 | 15632 | 1249 |
Ccr1,Ccl12,Ccl5,Swap70,Tnfsf14,Serpine1,Csf1,Il6,Pla2g7,Cxcl2,Cxcl14,Cd74,Cxcl10,Cx3cl1,Cxcl1,Cmklr1,Thbs1,Ccl4,Vegfc,Il1b,Pf4 |
| 1.893e-07 | -15.48 | positive regulation of type I interferon production | biological process | GO:0032481 | 52 | 16 | 20694 | 1406 |
Ifnar1,Stat1,Syk,Tlr3,Ifih1,Rnf135,Tlr2,Ddx58,Irf7,Irf1,Myd88,Cd14,Tlr9,Dhx58,Cgas,Zc3hav1 |
| 1.895e-07 | -15.48 | AMIT_EGF_RESPONSE_120_HELA | MSigDB lists | AMIT_EGF_RESPONSE_120_HELA | 62 | 19 | 15632 | 1249 |
Irs2,Kdm6b,Daxx,Plaur,Cdkn1a,Cxcl1,Clcf1,Cdc42ep2,Ogfr,Gem,Birc2,Dusp6,Tagln,Gdf15,Jag1,Dusp4,Maff,Sat1,Phlda1 |
| 1.895e-07 | -15.48 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | 62 | 19 | 15632 | 1249 |
Igf1r,Fam20c,Tgfbi,Map3k8,Irs2,Xrn1,Hp,Cxcl14,Gadd45g,Hspa2,Sat1,Ampd3,Bcl6,Cited2,Dusp1,Spsb1,Nr4a1,Gadd45b,Bcl2l11 |
| 1.909e-07 | -15.47 | regulation of tube size | biological process | GO:0035150 | 173 | 32 | 20694 | 1406 |
Gclc,Ptk2,Ednrb,Sirt1,Plod3,Pde5a,Gclm,Htr2a,Ahr,Icam1,Dock4,Cav1,Kat2b,Gja1,Htr2b,Edn1,Gch1,Map2k1,Adora2b,Dusp5,Cd38,Adrb2,Cx3cl1,Ptgs2,Tnf,P2ry2,Adora2a,Sod2,Kdr,Hif1a,Ptafr,Pdgfb |
| 1.929e-07 | -15.46 | DELPUECH_FOXO3_TARGETS_UP | MSigDB lists | DELPUECH_FOXO3_TARGETS_UP | 68 | 20 | 15632 | 1249 |
4930523C07Rik,Slc31a2,Abcc5,Dusp6,Cav1,Sema3c,Bcl6,Edn1,Sat1,Ccng2,Cd55,Marcksl1,Mxd1,Max,Dusp5,Kif3c,Cdc42ep2,Igf1r,Plaur,Mvp |
| 1.981e-07 | -15.43 | GSE40273_XBP1_KO_VS_WT_TREG_UP | MSigDB lists | GSE40273_XBP1_KO_VS_WT_TREG_UP | 179 | 36 | 15632 | 1249 |
Gch1,Irf7,Trim14,Cnn3,Timeless,Slc7a5,Stat4,Hat1,Oasl1,Aida,Parp11,Inpp1,Slfn9,Frmd6,Tspan3,Bcl6,Slfn8,Nat2,Pnp2,Stap1,Treml2,Gadd45g,Dusp4,Slc30a4,Cyth3,Sass6,Aldh1b1,Sell,Rtp4,Gbe1,Sdc4,Ube2f,Lpcat2,Ripk3,Daxx,Prpf38a |
| 1.981e-07 | -15.43 | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | 179 | 36 | 15632 | 1249 |
Hlx,Ddx60,Ccl22,Fgr,Sav1,Syk,Cyfip1,Dse,Homer1,Dock4,Tbc1d1,Spry2,Sat1,Egr2,Ifi44,Rin2,Hmox1,Slc31a1,Uchl1,Ripk2,Lyn,Tlr2,Clcn7,Slc29a3,Acp2,Tfec,Slc7a8,Atm,Plek,Plk2,Cd86,Serpine1,Lap3,Psme2,Tlr1,Pla2g7 |
| 1.989e-07 | -15.43 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | 234 | 43 | 15632 | 1249 |
Pcdh7,Inpp1,Adam19,Plat,Thbs1,Vegfc,Prkar2b,Dennd2a,Arid5b,Tmeff1,Nrp2,St3gal5,Plscr1,Mmd,Inhba,Met,Maff,Fzd1,Map4k4,Csrp1,Cav1,Sdc4,Plau,Pdgfc,Tnfaip3,Col18a1,Ccnd2,Irs2,Il4ra,Ctsc,Nr3c1,Peli1,Carhsp1,Sdc2,Chst11,Dpy19l1,Rab32,Dusp1,Apobec3,Ass1,Ppp1r14b,Timp1,Jun |
| 1.991e-07 | -15.43 | host intracellular part | cellular component | GO:0033646 | 20 | 10 | 20747 | 1409 |
Gbp7,Irgm2,Gbp2b,Gbp2,Gbp9,Gbp3,Pf4,Sco1,Iigp1,Gbp8 |
| 1.991e-07 | -15.43 | intracellular region of host | cellular component | GO:0043656 | 20 | 10 | 20747 | 1409 |
Gbp7,Gbp9,Gbp2,Gbp2b,Irgm2,Pf4,Gbp3,Sco1,Gbp8,Iigp1 |
| 2.019e-07 | -15.42 | GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP | MSigDB lists | GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP | 164 | 34 | 15632 | 1249 |
Itga4,Prdm1,Atp2b4,Slamf7,Rhbdf2,Ttc39c,Cyfip1,Pik3r5,Cx3cr1,Errfi1,Cish,Fcgr2b,Sema4a,Ell2,Ripk2,Kif5c,Ptprj,Ptger4,Il15ra,Epsti1,Cd82,Rgs1,Osbpl3,Gna15,Tnfsf14,Itgal,Ccl5,Tnfrsf1b,Myadm,Snx10,Slc4a7,Il18rap,Smpdl3b,Nfkbib |
| 2.024e-07 | -15.41 | regulation of actin filament-based process | biological process | GO:0032970 | 390 | 55 | 20694 | 1406 |
Cyfip1,Lpar1,Vasp,Cnn2,Tmod3,Whamm,Cdc42ep2,Hck,Csf3,Plek,Kcnj2,Hcls1,Dbnl,F11r,Rhof,Asap3,Cav1,Rictor,Myadm,Rnd3,Cdk5r1,Tlr2,Prkce,Spire1,Swap70,Rhoh,Ptger4,Bst1,Fchsd2,Rhou,Cx3cl1,Pdpn,Il1a,Nck1,Evl,Met,Cdc42ep4,Sdc4,Fgr,Edn1,Stap1,Rhoq,Notch2,Carmil1,Tmsb10,Frmd6,Rgcc,Icam1,Fscn1,Pde4b,Abracl,Pdgfrb,Rac3,Rhoc,Rnd1 |
| 2.061e-07 | -15.39 | GO_PROTEIN_PHOSPHORYLATION | MSigDB lists | GO_PROTEIN_PHOSPHORYLATION | 888 | 114 | 15632 | 1249 |
Tlk2,Stat5a,Tnf,Irak3,Sgk3,Tab2,Psmb10,Plk3,Il12rb1,Rapgef2,Osm,Map2k1,Pdgfrb,Ccl5,Dusp6,Il1b,Htr2b,Irak2,Ikbke,Kitl,Adora2b,Trib3,Map3k8,Il18,Il2rg,Tlr3,St3gal1,Crkl,Psmb6,Ripk2,Dusp4,Morc3,Eif2ak2,Sqstm1,Itgav,Syk,Spred1,Pim3,Il15,Mul1,Irs2,Cdk5r1,Nek6,Mmd,Rictor,Psme2,Cav1,Sik3,Atm,Nfkb1,Ikbkg,Vrk2,Jak2,Trib1,Map2k4,Lyn,Tlr9,Ptk2,Pim2,Acvr1,Ccnd1,Psma6,Acvrl1,Mlkl,Stk40,Dbnl,Psmb9,Lipe,Axl,Src,Ripk3,Daxx,Hck,Mdfic,Nod1,Bmp2,Fgr,Psme1,Lif,Pml,Tyk2,Pdgfb,Plk2,Map4k4,Prkx,Pim1,Ptger4,Scyl2,Dusp5,Nod2,Myc,Prkce,Psmd10,Flt1,Map3k6,Ccl12,Mark2,Angpt1,Ppm1l,Mapkapk2,Met,Rasgrp1,Akt3,Ksr1,Psmb8,Pdk3,Ccne1,Igf1r,Kdr,Fam20c,Acvr1b,Pik3cd,Tlr2,Dyrk2 |
| 2.064e-07 | -15.39 | GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP | MSigDB lists | GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP | 142 | 31 | 15632 | 1249 |
Txnrd1,Aoah,Acpp,Gpr18,Psmb9,Rab21,Tnc,Parp14,Dock10,Tmem176b,Hhex,Itga4,Phip,Cd74,Upp1,Slc28a2,Ncoa7,Arid4a,Pde4b,Casp4,Tmem176a,Itga5,Ptprj,Nr4a3,Acsl1,Cldnd1,Gcnt2,Gsta3,Agpat4,Epsti1,Igf1r |
| 2.077e-07 | -15.39 | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_UP | 187 | 37 | 15632 | 1249 |
Hk2,Il18rap,Slpi,H2-Aa,Hdc,Irf8,Zc3h12c,Cd86,Myadm,Ahrr,Rnf14,S100a8,Jarid2,Rgl1,Cdkn1a,Il1b,Igf1r,Actb,Il1rn,Gpd2,Hp,Hspa2,Carhsp1,Il4i1,Egr2,Fcgr2b,Casp3,Tcf4,Cd40,Swap70,Syk,Itgav,Cd38,Tnfrsf8,Cd180,Cd74,Hhex |
| 2.100e-07 | -15.38 | positive regulation of blood vessel diameter | biological process | GO:0097755 | 72 | 19 | 20694 | 1406 |
Adrb2,Plod3,Sirt1,Dusp5,Ednrb,Ptk2,Adora2b,Gch1,Ptafr,Hif1a,Kdr,Gja1,Kat2b,Sod2,Adora2a,Dock4,Tnf,Ahr,Cx3cl1 |
| 2.130e-07 | -15.36 | Cytokines and Inflammatory Response | WikiPathways | WP222 | 27 | 14 | 4813 | 540 |
Il15,Cxcl3,Il12b,H2-Eb1,Csf3,Csf1,Il1a,Il10,Ifnb1,Cxcl1,Il1b,Il6,Ifna1,Tnf |
| 2.134e-07 | -15.36 | LIU_VAV3_PROSTATE_CARCINOGENESIS_UP | MSigDB lists | LIU_VAV3_PROSTATE_CARCINOGENESIS_UP | 107 | 26 | 15632 | 1249 |
Tap1,Gbp2,Psmb10,Fabp3,Cd74,Ccnd2,Bcl2a1d,Sat1,Tnc,Psmb9,Bcl2a1b,Casp1,Tnfsf10,Plat,Bcl2a1a,Ifit3b,Tlr2,Irf1,Stat1,C3,Pla2g7,Plod2,Ifit3,Ltbp2,Ednrb,Psmb8 |
| 2.153e-07 | -15.35 | GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN | MSigDB lists | GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN | 195 | 38 | 15632 | 1249 |
Trim13,Cyth3,Il1a,Prdm1,Mxd1,Olr1,Batf,Clec4e,Acpp,Ehd1,Ezr,Hivep2,Bcl2l11,Nfkbie,Adora2b,Fpr1,Cdc42ep4,Hp,Itga5,Ptgir,Dtx2,Abcc1,Tnip1,Nfkb2,Ubr4,Zc3h12c,Lcn2,Rrs1,Ptch1,Birc3,Jarid2,Rnf14,Eya4,Met,Adora2a,Rab10,Gpr132,Stxbp3 |
| 2.162e-07 | -15.35 | GO_REGULATION_OF_CELLULAR_LOCALIZATION | MSigDB lists | GO_REGULATION_OF_CELLULAR_LOCALIZATION | 1162 | 141 | 15632 | 1249 |
Cd14,Cd38,Plagl2,Plk3,Aim2,Parp10,Rnf139,Rab21,Micall2,Rab11fip1,Nfkbie,Rbpms,Gpr68,Rsad2,Tnf,Traf2,Rhbdf2,Serp1,Sec24a,Il1b,Keap1,Htr2b,Tlr3,Hmox1,Adora2b,Il18,Stxbp3,Mmp13,Inhba,Fzd1,H2-Eb1,Gja1,Ccl5,Cd274,Fzd5,Osm,Map2k1,Cd34,Sdc4,Pim3,Slc16a1,Clec4e,Stxbp1,Sdc1,Ubash3b,Cdk5r1,Mul1,Nr1h3,Cx3cl1,Irs2,Slc30a1,Gsdmd,Syk,Jak2,Cdkn1a,Tlr9,Lyn,Slc9a1,Nfkbib,Rhou,Stx6,Pid1,Cav1,Casp8,Nos2,Notch1,Mdfic,Nfkbil1,Lif,Pml,Ddx58,Hif1a,Il1a,Fgr,Socs1,Sphk1,Rab9,Rhoq,Lztfl1,Kdm5b,Mdm2,Ehd1,Src,Hsph1,Ifnar1,Casp1,Lrp4,P2ry12,Itpr1,Slc2a1,Cd40,Bambi,Vegfc,Hcar2,Sec24b,Ptger4,Zc3h12a,Clec5a,Ptgs2,Il12b,Cxcl10,Ptafr,Tlr1,Csf3,G3bp2,Hap1,Txn1,Prdx1,Htr2a,Tnfrsf14,Angpt1,Abr,Tlr6,Il4ra,Nlrp3,Edn1,Prkce,Ppp2r5a,Il6,Nod2,Nfkbia,Ezr,Ccl12,Bcl2l11,Psmd10,Cacna1d,Hcls1,Pfkl,Stard7,Nlgn2,Tnfsf4,Dyrk2,Tlr2,Sirt1,Rasgrp1,Rabgef1,Clec4n,Rnf31,Il10,Tnfsf14,Rims3 |
| 2.166e-07 | -15.35 | GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN | MSigDB lists | GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN | 172 | 35 | 15632 | 1249 |
Atp2b4,Crim1,Tnfaip3,Sav1,Sgcb,Batf,Sla,Cyth3,Nlrp3,Aim2,Prdm1,Nek6,4932438A13Rik,Mecp2,Chst11,Slfn8,Nr3c1,Pde1b,Ttc39c,Rhbdf2,Aoah,Spsb1,Plekha5,Cflar,Ppp2r1b,Slfn9,Cd82,Pdzd11,Cpeb4,Dgkh,Il12rb1,Rnf19a,Rhou,Rap1gap2,C1rl |
| 2.166e-07 | -15.35 | GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_DN | 172 | 35 | 15632 | 1249 |
P2ry2,Nampt,Fcgr4,Rtn2,Plscr1,Rab20,Ier3,Ddx4,Fpr1,Ptgs2,Dram1,Trem1,Lhx2,Tnfsf10,Bambi,Gca,Bcl2a1a,Cd302,P2ry13,Slc7a11,Syk,Rapgef5,Dhrs9,Bcl2a1b,Sod2,Rab32,Cebpd,Bcl2a1d,Rsad2,Sdc2,Fgl2,Prkce,Apba1,Tlr6,Clcn5 |
| 2.174e-07 | -15.34 | LU_EZH2_TARGETS_DN | MSigDB lists | LU_EZH2_TARGETS_DN | 335 | 55 | 15632 | 1249 |
Apaf1,Tnfaip3,Rab11fip1,Axl,Abcc5,Birc2,Ankrd17,Pilrb1,Plat,Thbs1,Sec24a,Sec24b,Glrx,Phlpp2,Tnfsf15,Antxr1,Hk2,Fzd1,Dusp6,Tap2,Ascc3,Sgcb,Plau,Pilrb2,Pnpt1,Atp2b4,Nfkbiz,Lrp8,Palld,Trim13,Dcp2,Papss2,Irs2,Nlrp3,Cdk5r1,Phactr4,Gfpt1,Idi1,Hsd17b7,Kpna3,Denr,Ell2,Dyrk2,Acvr1b,Asb13,Acsl1,Ociad1,Bcl9,Casp2,Rabgef1,Eif4g2,Ccne1,Sema3c,Il10,Sco1 |
| 2.194e-07 | -15.33 | regulation of cytoskeleton organization | biological process | GO:0051493 | 536 | 69 | 20694 | 1406 |
Hsph1,Plk2,Plek,Hck,Csf3,Hspa1b,Cdc42ep2,Whamm,Hcls1,Dst,Cyfip1,Vasp,Lpar1,Tmod3,Mid1,Swap70,Gpsm2,Rhoh,Chmp4b,Dbnl,Asap3,Rhof,F11r,Rictor,Cav1,Cdk5r1,Tlr2,Prkce,Spire1,Rnd3,Myadm,Evl,Nck1,Cdc42ep4,Met,Sdc4,Ptger4,Mecp2,Tpx2,Cenpj,Bst1,Hspa1a,Trim36,Fchsd2,Il1a,Cx3cl1,Rhou,Fscn1,Pdgfrb,Gda,Mark2,Phldb1,Parp3,Rhoc,Agrn,Rnd1,Rac3,Fgr,Rhoq,Dync1h1,Tmem67,Edn1,Stap1,Kat2b,Tmsb10,Carmil1,Notch2,Rgcc,Icam1 |
| 2.215e-07 | -15.32 | extracellular membrane-bounded organelle | cellular component | GO:0065010 | 16 | 9 | 20747 | 1409 |
Pf4,Gbp3,Iigp1,Gbp8,Gbp7,Gbp9,Gbp2b,Irgm2,Gbp2 |
| 2.223e-07 | -15.32 | positive regulation of type 2 immune response | biological process | GO:0002830 | 16 | 9 | 20694 | 1406 |
Il18,Il6,Nlrp3,Clcf1,Tnfsf4,Cd74,Rsad2,Nod2,Il4ra |
| 2.271e-07 | -15.30 | GO_RESPONSE_TO_HEAT | MSigDB lists | GO_RESPONSE_TO_HEAT | 81 | 22 | 15632 | 1249 |
Thbs1,Lrp11,Tfec,Cdkn1a,Il1b,Hmox1,Socs3,Dnaja2,Dnajb4,Lyn,Cxcl10,Osm,Cd14,Gclc,Il1a,Pla2g4a,Il6,Hspa2,Psip1,Ccl12,Dnaja1,Hspa1a |
| 2.310e-07 | -15.28 | GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_DN | MSigDB lists | GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_DN | 150 | 32 | 15632 | 1249 |
Nfkbiz,Atf3,Nlrp3,Gpr141,Dcp2,Gng11,Sdc4,Slc25a25,Txnrd1,Ccl12,Gadd45b,Rhbdf2,Homer1,Rnf24,Pde5a,Ccng2,Pim2,Ier3,Nr4a3,Thbs1,Dr1,Il1rn,Cxcl1,Cflar,Pf4,Jdp2,Eif4g2,Hopx,Phlda1,Wdfy1,Procr,Casp2 |
| 2.310e-07 | -15.28 | GENTILE_UV_HIGH_DOSE_DN | MSigDB lists | GENTILE_UV_HIGH_DOSE_DN | 293 | 50 | 15632 | 1249 |
Nr3c1,D1Ertd622e,Casp3,Sat1,Cebpd,Tlk2,N4bp1,Dusp1,Tpst1,Tnfaip3,Nupr1,Jmjd6,Isg15,Stxbp3,Ddit4,Maff,Rapgef2,Pde4b,Thbs1,Sec24b,Pkp4,Vegfc,Dusp5,Crkl,Arid5b,Cdc42ep4,Morc3,Tiparp,Trip10,Rnd3,Rras2,Atf3,Rars,Nck1,Pikfyve,Il4ra,Trim13,Zfp36,Spen,Eef1e1,Met,Gem,Casp8,Ppp2r1b,Rbms1,Dr1,Nfil3,Filip1l,Ptk2,Lpar1 |
| 2.329e-07 | -15.27 | transferase activity, transferring phosphorus-containing groups | molecular function | GO:0016772 | 908 | 104 | 20217 | 1400 |
Pdgfrb,Prkx,Fam20c,Mapkapk2,Oas1b,Igf1r,Syk,Ripk3,Gk,Sla,Eif2ak2,Src,Acvr1b,Mark2,Pim2,Cdkn1a,Sgk3,Dgkh,Pik3cd,Cdk5r1,Hck,Atm,Tent2,Hk1,Fgr,Pgs1,Axl,Dck,Jak2,Met,Map2k4,Ccnj,Pik3r6,Sik3,Plk2,Dgka,Nrp2,Oasl1,Prkce,Lyn,Grk3,Ptk2,Dyrk2,Trib1,Ccnd1,Pim3,Tent4a,Oas3,Ksr1,Itpkc,Cmpk2,Pikfyve,Prag1,Stk40,Plk3,Flt1,Pgk1,Acvrl1,Pdk3,Cept1,Pfkl,Map4k4,Ikbke,Sphk1,Gmppb,Map3k6,Pim1,Hk2,Map3k8,Ccl5,Mlkl,Gys1,Nek6,Sgms2,Papss2,Ccng2,Ccnd2,Hk3,Map2k1,Etnk1,Ripk2,Cgas,Oas1a,Vrk2,Trib3,Mmd,Kdr,Ccne1,Polr2g,Tyk2,Oas2,Acvr1,Oasl2,Ak4,Irak3,Scyl2,Tut7,Pnpt1,Akt3,Oas1g,Tlk2,Pfkfb3,Ciita,Irak2 |
| 2.352e-07 | -15.26 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | 165 | 34 | 15632 | 1249 |
Nfkbiz,Rnf139,Ubash3b,Gbp3,Cdk5r1,Irs2,Dtx3l,Mpp7,Cd83,Samhd1,Dusp1,Parp8,Casp1,Pik3r5,Mtus1,Jun,Tnfsf8,Herc6,Socs3,Pim1,Trib1,Whamm,Snn,S100a8,Plek,Junb,Map4k4,Sesn3,Klf2,Casp4,Rapgef2,Cd69,Rap1gap2,Maff |
| 2.370e-07 | -15.26 | symbiont process | biological process | GO:0044403 | 237 | 39 | 20694 | 1406 |
Jun,Irgm2,Ccl4,Gbp7,Gbp9,Gbp2b,Pvr,Pml,Denr,Gbp3,Hdac1,Gbp2,Pf4,Clec5a,Irgm1,Bcl2l11,Trem1,Rab9,Tnfrsf14,Pcx,Cav1,Tnip1,Ccl5,Serpinb9,Icam1,Ripk3,Tlr2,Zbp1,Itgav,Vcam1,Axl,Cd55,Chmp4b,Nectin2,Cd300lf,Myc,Zc3h12a,Nectin4,Mmp9 |
| 2.391e-07 | -15.25 | GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP | MSigDB lists | GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP | 57 | 18 | 15632 | 1249 |
Tnfsf10,Cxcl1,Gbp2,Ppfibp1,Il1b,Hlx,Ebi3,Tnfsf4,Cxcl10,Ptgs2,Maff,Cxcl2,Inhba,Optn,Rbpms,Tra2a,Stat4,Sod2 |
| 2.391e-07 | -15.25 | GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_DN | 188 | 37 | 15632 | 1249 |
Csf1,Phlda1,Tifa,Itgal,Lmo4,Txn1,Ccne1,Ccl5,5430427O19Rik,Orai2,Cd82,Adam19,Plat,Cldnd1,Cacnb3,Mthfd2,Spire1,Ebi3,Ell2,Psmb6,Nod2,Gpr68,Nqo1,Casp3,Fut8,Pde1b,Trip10,Bcl6,Spn,Ezr,Plekha5,Myd88,Rnf135,Aim2,Prrg4,Mcoln2,Tlr6 |
| 2.391e-07 | -15.25 | P53_DN.V1_DN | MSigDB lists | P53_DN.V1_DN | 188 | 37 | 15632 | 1249 |
Ifi209,Ifi205,Mtus1,Bcl2a1b,Casp1,Ifi213,Nr4a1,Bcl2a1d,Hspa2,Vcan,Rhoq,Pla2g4a,Irf4,St3gal6,Ifi214,Itga4,Fas,Ifi207,Mndal,Itgal,Pde4b,Nampt,Ifi203,Stat4,Oas1a,St3gal5,Ifi208,Btg2,Ifi211,Nrp2,Nr4a3,Ifi204,Hmox1,Oas1g,Socs3,Cdkn1a,Bcl2a1a |
| 2.393e-07 | -15.25 | SCHLOSSER_SERUM_RESPONSE_DN | MSigDB lists | SCHLOSSER_SERUM_RESPONSE_DN | 637 | 88 | 15632 | 1249 |
Ifi205,Ifi213,Casp1,Tbc1d1,Minpp1,Ly75,Kdm4a,Crim1,Cd164,Cnp,Arid4a,Gch1,Wars,Oas2,Ube2l6,Nmi,Ifi208,Cd55,Oas1g,Smc5,Glrx,Zhx2,Sec24b,Tcea1,Plcl2,Snapc1,Clic4,Psmd10,Tra2a,Irf4,Dmxl2,Prdx1,Oas1a,Jag1,Rasgrp1,Ifi203,Hat1,Pik3cd,Stat1,Dck,Stard7,Prkar2b,Tmem123,Ifi209,Rbpms,Ccng2,Rsad2,Phgdh,Sat1,Rab21,Rnf24,Kmo,Apaf1,Myd88,Cacybp,Tor1aip1,Asns,Snx2,Stxbp3,Pkp4,Pgk1,Sec24a,Ets2,Eif2ak2,Morc3,Ass1,Psip1,Phlpp1,Pla2g4a,Pikfyve,Ifi214,Ifi207,Atp11b,Col4a2,Mndal,Mmd,Tdrd7,Ifi211,Psme2,Mppe1,Ifi204,Map2k4,Mtdh,Pim2,Adam19,Idi1,Ldlr,Tax1bp1 |
| 2.401e-07 | -15.24 | ACTGTGA_MIR27A_MIR27B | MSigDB lists | ACTGTGA_MIR27A_MIR27B | 424 | 65 | 15632 | 1249 |
Ccnj,Fosb,Flrt2,Plk2,Phlpp2,Nrp2,Btg2,Reps1,Pde7b,Eya4,Dusp5,Ptger4,Usp42,Adora2b,Prkx,Gng12,N4bp1,Rab11fip1,Stk40,Acvr1,Zfp800,Tlk2,Rnf139,Csrnp1,Lif,Hlx,Fam133b,Slc39a13,Ube2f,Plagl2,Ncoa7,Clcn5,Apaf1,Mier3,Rims3,Bcorl1,Csf1,Mmd,Itpkc,Itga5,Ell2,Kpna3,Cpeb4,Map2k4,Adam19,Rgs1,Rpgrip1l,Sh3bgrl2,Armc8,H3f3b,Agpat4,Stard7,Flrt3,Slc7a11,Agrn,Irf4,Spry2,Ncoa5,Nek6,Nxf1,Arrdc4,Tmtc2,Dcp2,Rnd3,Foxp4 |
| 2.426e-07 | -15.23 | KEGG_VIRAL_MYOCARDITIS | MSigDB lists | KEGG_VIRAL_MYOCARDITIS | 75 | 21 | 15632 | 1249 |
Ccnd1,H2-Aa,Casp3,Cycs,Cd40,Casp8,Cd86,Cav1,Itgal,H2-Q6,H2-Eb1,H2-Q4,Eif4g2,Cd80,Actb,Sgcb,Icam1,Rac3,Cd55,H2-Q7,H2-Ab1 |
| 2.470e-07 | -15.21 | GO_POSITIVE_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION | 18 | 10 | 15632 | 1249 |
Cd80,Il6,Il12rb1,Ripk2,Hlx,Tnfsf4,Il12b,Il4ra,Nlrp3,Cd86 |
| 2.515e-07 | -15.20 | response to hormone | biological process | GO:0009725 | 624 | 77 | 20694 | 1406 |
Hcls1,Ass1,Map2k1,Stat2,Src,Stat3,Cd38,Nr3c1,Serpina3f,Nos2,Lox,Sesn3,Cflar,Acsl1,Cyfip1,Il6,Notch1,Pid1,Akt3,Trib3,Sirt1,Il18,Ccnd1,Cdk5r1,Prkce,Nr4a3,Lyn,Cav1,Inhba,Nfkb1,Jak2,Timp1,Stat1,Acod1,Crkl,Ddit4,Nr4a1,Glrx,Tnfsf4,Il10,Agtrap,Irf1,Slc9a1,Me1,Serpina3g,Tnf,Daxx,Jun,Stat5a,Egr2,Mmp13,Stat4,Ptger4,Cacybp,Pde3b,Atp2b4,Il1rn,Gclc,Nr1h3,Mmp14,Ptk2,Ptpn2,Ednrb,Zfp36,Junb,Egr1,Rab10,Fas,Ifnb1,Kat2b,Irs2,Stxbp3,Phip,Rhoq,Socs7,Dnaja1,Igf1r |
| 2.530e-07 | -15.19 | regulation of T-helper 1 type immune response | biological process | GO:0002825 | 30 | 12 | 20694 | 1406 |
Ripk2,Hlx,Il12rb1,Il4ra,Il27,H2-Ab1,Irf1,Il18,Il1b,Arid5a,Il12b,Tnfsf4 |
| 2.543e-07 | -15.18 | GO_RESPONSE_TO_TEMPERATURE_STIMULUS | MSigDB lists | GO_RESPONSE_TO_TEMPERATURE_STIMULUS | 136 | 30 | 15632 | 1249 |
Il6,Pla2g4a,Hspa2,Psip1,Ccl12,Plac8,Nfkbia,Dnaja1,Hspa1a,Fos,Cd14,Gclc,Htr2a,Rnf34,Il1a,Casp8,Osm,Thbs1,Lrp11,Cdkn1a,Il1b,Htr2b,Tfec,Hmox1,Socs3,Dnaja2,Lyn,Adrb2,Cxcl10,Dnajb4 |
| 2.544e-07 | -15.18 | positive regulation of macroautophagy | biological process | GO:0016239 | 66 | 18 | 20694 | 1406 |
Pim2,Trim13,Sirt1,Irgm1,Adrb2,Optn,Bnip3,Tlr2,Hmox1,Nod2,Irgm2,Nod1,Sesn3,Ripk2,Ikbkg,Hif1a,Kdr,Larp1 |
| 2.552e-07 | -15.18 | positive regulation of leukocyte chemotaxis | biological process | GO:0002690 | 87 | 21 | 20694 | 1406 |
Edn1,Cxcl14,Ccl4,Cxcl10,Cmklr1,Vegfc,Tnfsf14,Ccl5,Cx3cl1,Csf1,Sell,Serpine1,Pla2g7,Swap70,Ccl2,Thbs1,Il1b,Ptprj,Fpr2,Cd74,Ccr1 |
| 2.558e-07 | -15.18 | ATP binding | molecular function | GO:0005524 | 1385 | 145 | 20217 | 1400 |
Irak2,Ehd1,Ube2l6,Ciita,Ascc3,Hspa1b,Tlk2,Ube2e1,Akt3,Scyl2,Irak3,Ak4,Abcc5,Oasl2,Mthfd1l,Acvr1,Nod1,Oas2,Tyk2,Atp10a,Helz2,Kdr,Tap1,Ass1,Trib3,Vrk2,Clcn7,Myo10,Cgas,Ripk2,Etnk1,Clcn5,Map2k1,Hk3,Hspa1a,Slfn9,Papss2,Ube2f,Pcx,Nek6,Dnaja1,Mlkl,Tor3a,Map3k8,Hk2,Map3k6,Pim1,Sphk1,Ddx58,Ikbke,Map4k4,Nlrp3,Pfkl,Pdk3,Acvrl1,Nlrc4,Myo1b,Pgk1,Flt1,Slfn5,Plk3,Stk40,Prag1,Smc5,Pikfyve,Cmpk2,Cenpe,Itpkc,Oas3,Ksr1,Atp2b4,Tent4a,Pim3,Wars,Apaf1,Trib1,Gclc,Dyrk2,Grk3,Ptk2,Atp11a,Abcc1,Ube2e2,Lyn,Prkce,Abcb1a,Ddx4,Oasl1,Chd9,Trip13,Nod2,Katna1,Dgka,Nlrc5,Plk2,Atp13a1,Dnaja2,Sik3,Ep400,Srxn1,Actb,Rars,Map2k4,Met,Jak2,Asns,Dck,Dync1h1,Axl,Hk1,Pgs1,Fgr,Tent2,Acsl1,Hck,Atm,Tap2,Hsph1,Pik3cd,Dhx58,Mcm9,Swap70,Sgk3,Pim2,Kif3c,Mark2,Acvr1b,Kif9,Hspa2,Eif2ak2,Ifih1,Src,Gk,Mcm6,Igf1r,P2ry2,Syk,Ripk3,Slfn8,Fam20c,Prkx,Mapkapk2,Acsl5,Pdgfrb,Mov10 |
| 2.573e-07 | -15.17 | Pept_C14_p20 | interpro domains | IPR001309 | 12 | 8 | 19984 | 1430 |
Casp3,Casp2,Casp1,Cflar,Malt1,Casp4,Casp7,Casp8 |
| 2.573e-07 | -15.17 | Caspase-like_dom_sf | interpro domains | IPR029030 | 12 | 8 | 19984 | 1430 |
Casp4,Malt1,Casp2,Casp3,Cflar,Casp1,Casp8,Casp7 |
| 2.593e-07 | -15.17 | GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | MSigDB lists | GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 962 | 121 | 15632 | 1249 |
Bnip3,Ifrd1,Cited2,Col4a2,Cd34,Bcor,Cx3cl1,Mul1,Cdk5r1,Znrf3,Psme2,Csf1,Rhou,Sema3c,Pid1,Ust,Vrk2,Itga5,C3,Rac3,Mtdh,Sema4c,Ptk2,Lpar1,Rab21,Glipr2,Phldb1,Ddhd1,Tnf,Bcl6,Tnfaip3,Etv5,Psmb10,Fzd1,Ppp2r3a,Tbc1d13,Rapgef2,Vasn,Ccl5,Gdf15,Dusp6,Brwd3,Myadm,Serpine1,Map2k1,Fzd5,Ppp1r15a,Gcnt2,Il1b,Psmb6,Hmox1,Atp10a,Cdc42ep4,Pdpn,Ccl2,Il6,Myc,Edn1,Ccr3,Triobp,Sdc2,Ccl12,Ezr,Cx3cr1,Flt1,Cyfip1,Psmd10,Cdc42ep2,Pde3b,Plau,Mark2,Lrp8,Abr,Il4ra,Phip,Cysltr2,Sirt1,Psmb8,Tnfsf14,Kdr,Cflar,Stat1,Adrb2,Sema4a,Rhoq,Tbc1d1,Acvrl1,Psma6,Lrp4,Src,Ehd1,Psmb9,Bmp2,Myo10,Hck,Notch1,Lif,Pml,Hhex,Psme1,Sphk1,Fgr,Il1a,Hif1a,Icam1,Hap1,Wars,Pik3r6,Sipa1l1,Daam1,Thbs1,Bambi,Il1rn,Sec24b,Pf4,Vegfc,Fmnl2,Zc3h12a,Ptger4,Cxcl10,Ptgs2 |
| 2.600e-07 | -15.16 | GO_RESPONSE_TO_HYDROGEN_PEROXIDE | MSigDB lists | GO_RESPONSE_TO_HYDROGEN_PEROXIDE | 108 | 26 | 15632 | 1249 |
Jun,Klf6,Src,Dusp1,Mdm2,Il18bp,Il6,Bnip3,Casp3,Pla2g4a,Sphk1,Sdc1,Hif1a,Fas,Olr1,Tnfaip3,Pdgfrb,Klf2,Ppp1r15b,Il18rap,Sirt1,Nr4a3,Hmox1,Ldha,Hp,Kdm6b |
| 2.628e-07 | -15.15 | positive regulation of protein kinase B signaling | biological process | GO:0051897 | 102 | 23 | 20694 | 1406 |
Ptprj,Hcls1,Cx3cr1,F10,Angpt1,Csf3,Gcnt2,Src,Thbs1,Phlpp1,Cx3cl1,Tnf,P2ry12,Il6,Axl,Ptk2,Il18,Gdf15,Spry2,Osm,Rictor,Mtdh,Igf1r |
| 2.643e-07 | -15.15 | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 181 | 36 | 15632 | 1249 |
Jarid2,Rabgef1,Tnfrsf1b,Rnaset2a,Plscr1,Hat1,Etv6,Cd55,Kdm6b,Il13ra1,Trib1,Acsl1,Ptafr,Mmp25,Jak2,Bcl2a1a,Orai2,Cxcl1,Hcls1,Thbs1,Rnaset2b,Snn,Txnrd1,Bcl2a1b,Syk,Fos,Acpp,Cd302,Tpst1,Tbc1d1,Ccr3,Bcl2a1d,Isg15,Pikfyve,Sla,Tle3 |
| 2.643e-07 | -15.15 | GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 181 | 36 | 15632 | 1249 |
Tdrd7,Zfp36,P4ha1,4930523C07Rik,Gfi1,Frmd6,Adam19,Tlr2,Arid5b,Map2k4,Rcan1,Tmod3,Socs3,B3gnt5,Kdm5b,Treml2,Errfi1,Sat1,Irgm2,Tiparp,Tet2,Slc25a37,Fam43a,Nfkbia,Hck,Daxx,Cd38,Lpcat2,Sdc4,Rtp4,Arl4a,Zfp281,Spata13,Sdc1,Cyth3,Kmo |
| 2.643e-07 | -15.15 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_UP | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_UP | 181 | 36 | 15632 | 1249 |
Cers6,Gsr,Kremen1,Sele,Rab11fip1,Pdpn,Il6,Ctsc,Hmga1,Mgat1,Arid5a,Slc7a11,Cst7,Spsb1,Nr4a1,Cd38,Lipg,Pbx1,Nlrp3,Hif1a,Slc39a14,Pdlim7,Antxr1,Ddit4,Wdfy1,Rel,Ppp1r15a,Pde4b,Nlgn2,Nfil3,Tcea1,Dio2,Thbs1,Dusp5,Socs3,Hmox1 |
| 2.643e-07 | -15.15 | GSE34515_CD16_NEG_MONOCYTE_VS_DC_UP | MSigDB lists | GSE34515_CD16_NEG_MONOCYTE_VS_DC_UP | 181 | 36 | 15632 | 1249 |
Cenpe,N4bp1,Sod2,Swap70,Rhbdf2,Mdm2,4932438A13Rik,Ccng2,Itga4,Fpr2,Ubash3b,Upp1,Rnf135,Crlf3,Spred1,Tnfrsf14,Hk3,Rhoc,Gbp2,Plagl2,Lnpep,Dusp6,Tuba4a,Tnfrsf1b,Sipa1l1,Adap2,Ext1,Tlr1,Slc2a6,St3gal5,Cpeb4,Dusp5,Tmod3,C3,Ell2,Cd300lf |
| 2.643e-07 | -15.15 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP | 181 | 36 | 15632 | 1249 |
Acsl1,Oas1g,Dgka,Usp12,Slamf9,Stat4,Oas1a,Lmo4,Lgals9,Card6,Samhd1,Clcn5,Klf7,Sdc4,St3gal6,Calcrl,Prnp,Kmo,Ddx58,Mcoln2,Slc30a4,Rsad2,Dusp4,Stk40,Cdyl2,Phlpp1,Kdm5b,Treml2,D1Ertd622e,Oas3,Bcl2l11,Ass1,Gypc,Spn,Stat5a,Fam43a |
| 2.660e-07 | -15.14 | GO_NEGATIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 122 | 28 | 15632 | 1249 |
Trib1,Pim1,Tlr9,Tnfsf4,Zc3h12a,Hmox1,Gfi1,Keap1,Cmklr1,Tax1bp1,Irak2,Ptch1,Sirt1,Nfkbid,Trim21,Med13,Prnp,Nlrp3,Nfkbil1,Aim2,Parp10,Tnfaip3,Irak3,Pbx1,Psmd10,Nfkbia,Nlrc5,Peli1 |
| 2.660e-07 | -15.14 | WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | MSigDB lists | WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | 122 | 28 | 15632 | 1249 |
Fosb,Serpine1,H2-Eb1,Myadm,Dusp6,Tnfrsf1b,Odc1,Pim2,Socs3,Mmp9,Pf4,Pmepa1,Gbp2b,Ccl4,H2-Q6,Arid5a,Jun,Nr4a1,H2-Q4,C1ra,Parp14,Dusp2,Atf3,H2-Q7,Rgs3,Tnfaip3,Cd34,Sdc4 |
| 2.691e-07 | -15.13 | GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS | 372 | 59 | 15632 | 1249 |
Rnf19a,Sirt1,Psme2,Zfp36,Trim21,Cav1,Rnf14,Tnfrsf1b,Ankib1,Psmb8,Dnajb2,Kdr,Polr2g,Mefv,Adrb2,Trib1,Pim2,Mtdh,Ptk2,Prkce,Bnip3,Ctsc,Tiparp,Psmd10,Sqstm1,Rnf114,Ezr,Zc3hav1,Pnpt1,Gclc,Htr2a,Irs2,Trim13,Ppp2r3a,Sh3bp4,Btg2,Plk2,Gja1,Il1b,Keap1,Trib3,Smc5,Psmb6,Ripk2,Zc3h12a,Larp1,Rnf19b,Psma6,Mdm2,Psmb9,Tnf,Tnfaip3,Nod1,Psmb10,Hif1a,Rnf139,Plk3,Psme1,Ube2e1 |
| 2.692e-07 | -15.13 | Lung fibrosis | WikiPathways | WP3632 | 61 | 22 | 4813 | 540 |
Ccl5,Ccl3,Cxcl2,Mt2,Mecp2,Cysltr2,Atp11a,Csf3,Pdgfb,Plau,Timp1,Tnf,Ccl4,Mmp9,Ccl2,Il12b,Ccr3,Hmox1,Il1b,Elmod2,Il6,Edn1 |
| 2.708e-07 | -15.12 | CARD | pfam domains | PF00619 | 24 | 11 | 18711 | 1348 |
Nod1,Card6,Casp1,Birc2,Casp4,Ripk2,Nlrc4,Casp2,Nod2,Birc3,Apaf1 |
| 2.735e-07 | -15.11 | GSE21033_1H_VS_12H_POLYIC_STIM_DC_UP | MSigDB lists | GSE21033_1H_VS_12H_POLYIC_STIM_DC_UP | 166 | 34 | 15632 | 1249 |
Ralgds,Nfkb2,Dusp16,Igf1r,Fmnl2,Arl5c,Dusp5,Dck,Parp11,Usp42,Map3k8,Zeb1,Spen,Cnn3,Btg2,Rasgrp1,Spint2,Pfkfb3,Sla,Olfml3,Kmo,Agtrap,Socs1,Gbp3,Errfi1,Nr4a1,Ezr,Plekhf2,Ppp1r14b,Pik3r5,Otud1,Rgs14,Tmem184b,Mgat1 |
| 2.749e-07 | -15.11 | GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_UP | MSigDB lists | GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_UP | 189 | 37 | 15632 | 1249 |
Tbc1d13,Tdrd7,Csf1,Ube2l6,H2-Aa,Slfn4,Tor1aip1,Gbp7,Slc7a8,Plaur,Slfn3,Il1rn,Aida,Slamf8,Rin2,Ccdc86,Ccl2,Itpr1,Zyx,Ifit2,Ppp1r14b,Clcn5,Sgcb,Traf5,Sgk3,Ciita,F10,Myd88,Cd74,Psmb10,P2ry14,Fgr,Slc30a4,Evl,Psme1,Ube2e1,Usp25 |
| 2.760e-07 | -15.10 | GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | 41 | 15 | 15632 | 1249 |
Rffl,Hspa1a,Casp8,Ptpn2,Birc2,Traf2,Rnf31,Syk,Ikbkg,Birc3,Tnf,Tnfaip3,Tax1bp1,Traf1,Sphk1 |
| 2.760e-07 | -15.10 | SCHRAETS_MLL_TARGETS_UP | MSigDB lists | SCHRAETS_MLL_TARGETS_UP | 41 | 15 | 15632 | 1249 |
Fas,Ifi204,Ifi214,Cd34,Ifi207,Ifi213,Fos,Ifi209,Mndal,Ifi205,Ctsc,Ifi211,Tnc,Ifi208,Ifi203 |
| 2.788e-07 | -15.09 | nucleoplasm | cellular component | GO:0005654 | 2554 | 236 | 20747 | 1409 |
Hilpda,Cenpe,Hspa1a,Oasl1,Cdkn2d,Med13,Ikbke,Mcmbp,Vezt,Hif1a,Dennd1b,Smox,Ep400,Kat2b,Rbbp8,Psma6,Tut7,Ago3,Lnpk,Slc44a1,Ccnd2,Relb,Ccnd1,Stat3,Pbx1,Sinhcaf,Kdm4a,Ifi211,Mxd1,Ccne1,Lap3,Gbp2,Pfkfb3,Tcea1,Oas3,Mppe1,Serpinb9,Parp9,Gja1,Sqstm1,Rpgrip1l,Spire1,Ell2,Uchl1,Setdb2,Tap2,Stxbp1,Psme2,Actb,Casp8,Trim21,Plekhg1,Hinfp,Isg20,Dusp4,Prdm9,Hivep2,Golga3,Carmil1,Nfkb1,Morc3,Zhx2,Dusp16,Mtdh,Ptk2,Htr2b,Polr2g,Cacybp,Hat1,Ahrr,Oas1g,Notch2,Smc5,Slc9a1,Tnip1,Bcl6,Arl4a,Trip10,Oas1a,Socs1,Ets2,Max,Dock10,Birc3,Aldh1b1,Psme1,Mcm6,Aebp2,Rbpms,Spen,Rilpl1,Plagl1,Mdm2,Tent4a,Rars,Mier3,Daxx,Stat5a,Med21,Nek6,Phlpp1,Hck,Adar,Rgs14,Gpc1,Stat1,Phf11d,N4bp1,Stx6,Arid4a,Rel,Itpkc,Shfl,Olr1,Kdm6b,Dyrk2,Stk40,Jmjd6,Plekha5,Upp1,Etv5,Phf11a,Ctsc,Sp100,Ikzf1,Stap1,Sh3bgrl2,Phf11b,Keap1,Mark2,Top3a,Vps54,Gch1,Dtx2,Hsph1,Egr1,Ifi204,Maml2,Abtb2,Dtx3l,Nxf1,Bcorl1,Irf8,Ciita,Phf11c,Jak2,Txnrd1,Asf1a,Sap30,Egr2,Clcn7,Cdk5r1,Rbl1,Dcp2,Tle3,Mpp7,Cnp,Tasor2,Pml,Batf,Dse,Fos,Kdm5b,Dr1,Ptpn2,Pou2f2,Oas2,Agtrap,Klf8,Sirt1,Junb,Mafk,Bnip3,P4ha2,Psmb6,Etnk1,Cdyl,Cx3cr1,Il15,Zeb1,Cyth3,Jun,Rapgef5,Oasl2,Fubp1,Samhd1,Cenpj,Irf2,Dnajb4,Irf4,Nampt,Ppp4r2,Rnf34,Crkl,Rgs3,Cebpd,Myc,Aim2,Brd2,Mapkapk2,Higd1a,Ciapin1,Eef1e1,Taf4b,Fas,Klf3,Tfec,Gsdmd,Irf7,Arid5a,Nmi,Prpf4,Oas1b,Ubr4,Zc3h12a,Jarid2,Ier2,Tpx2,Phf6,Nr3c1,Zfp281,Nfkbiz,Cutc,Sik3,Asap3,Bbx,Casz1,Aff1,Cdkn1a,Fosb,Alas1,Gfi1,Spata13,Hdac1,Etv3,Psip1 |
| 2.824e-07 | -15.08 | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | 245 | 44 | 15632 | 1249 |
Spint2,Vasn,Lad1,Plk2,Tuba4a,Sesn3,Dusp6,Nfkb2,Thbs1,Plat,H2-Ab1,Errfi1,Egr2,Tnc,Sat1,Bcl6,Hspa1a,Slc2a1,Timp1,Arhgef3,Cd14,Arg2,Marcksl1,Pla2g7,Htra1,Slpi,Cnn3,Lcn2,Wdr43,Nfil3,Gsta3,Dusp16,Tnfaip2,Cxcl14,Vcan,Jun,Fos,Plac8,Ezr,Tle3,Rnd3,Sdc4,Sdc1,Palld |
| 2.829e-07 | -15.08 | BOQUEST_STEM_CELL_DN | MSigDB lists | BOQUEST_STEM_CELL_DN | 197 | 38 | 15632 | 1249 |
Csf3,Wars,Ccrl2,Met,Xaf1,Stx11,Isg20,Phlda1,H2-Aa,Lcp2,Clic5,Tnfrsf1b,Dusp6,Pkp4,Cflar,Kdr,Rcan1,Adrb2,H2-Ab1,Sele,Scarf1,Pnp2,Swap70,Ets2,Flt1,Rapgef5,Enpp4,Myo10,Il15,Gng11,F11r,Upp1,Cd74,Ifih1,Cx3cl1,Rnd1,Hhex,Pgs1 |
| 2.857e-07 | -15.07 | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | MSigDB lists | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | 435 | 66 | 15632 | 1249 |
Cpd,Abcb1a,Jun,Fos,Ahr,Slamf7,Sgcb,Ciita,Plagl1,Tpi1,Kctd12,Stat4,Plscr1,Timeless,Zc3h7a,Gem,Zc3h12c,Pdk3,Pmepa1,Pfkl,Ccl4,Rgs1,Sh3bgrl2,Actb,Socs3,Endod1,B3gnt5,Fgl2,Lztfl1,Ly75,Sat1,Phgdh,Oaf,Tcf4,Cd302,Hspa1a,Klf6,Mdfic,Rhoc,Ripk3,Crim1,Cd38,St3gal6,Tulp3,Mcoln2,Marcksl1,Mmp13,Wdfy1,Icosl,Asns,Hopx,Csrp1,Ccl5,Myadm,Slc13a3,Ccr1,Il1b,Plaur,Gca,Cxcl1,Ttc39b,Cxcl10,Ptgs2,Ptprj,Tlr3,Rnf19b |
| 2.872e-07 | -15.06 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP | 82 | 22 | 15632 | 1249 |
Pim2,Mmp9,Stat1,Rbms1,Actb,Hcls1,Lcn2,S100a8,Psmb8,Ccl5,Tnfrsf1b,Wars,Ube2l6,Isg20,Il4ra,Rhoh,Gbp2,Fcgr1,Cd14,Sla,Aoah,Eif2ak2 |
| 2.919e-07 | -15.05 | immune response-regulating cell surface receptor signaling pathway | biological process | GO:0002768 | 159 | 30 | 20694 | 1406 |
Zc3h12a,Fcgr4,Malt1,Fpr1,Rnf31,Pde4b,Dennd1b,Clec4e,Nr4a3,Tlr2,Clec4d,Themis2,Lyn,Nfkbid,Lcp2,Crkl,Nfkbiz,Cd40,Fcgr2b,Fpr2,Icosl,Cd38,Fcgr1,Spn,Cacnb3,Ripk2,Bcl2a1d,Cmklr1,Syk,Klrk1 |
| 2.919e-07 | -15.05 | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN | MSigDB lists | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN | 221 | 41 | 15632 | 1249 |
Cnn3,Spen,Casp2,Egln3,Snx10,P4ha1,Asns,Cacybp,Hopx,Casp8,Thbs1,Plaur,Pkp4,Armc8,Pf4,Il13ra1,Tmod3,Cd200,Ptafr,Il2rg,Spata5l1,Bnip3,Fcgr2b,Ifi44,4932438A13Rik,Cept1,Kdm5b,Ccnd1,Cx3cr1,Ezr,Axl,P4ha2,Slc16a3,N4bp1,Ass1,Sp140,Gpr18,Rras2,Smg7,Tpi1,Socs1 |
| 2.938e-07 | -15.04 | negative regulation of cellular macromolecule biosynthetic process | biological process | GO:2000113 | 1366 | 141 | 20694 | 1406 |
Nr1h3,Etv6,Zeb1,Kdm5b,Zfp36,Cebpd,Ptpn2,Myc,Nsd3,Xrn1,Edn1,Klf2,Spen,Tnfsf4,Hinfp,Ezr,Dach1,Irf1,Dcp2,Hdac1,Slfn1,Eif2ak2,Hopx,Aebp2,Arid4a,Ets2,Plekhn1,Mov10,Mecp2,Notch1,Mndal,Gfi1,Rnf139,Zc3h12a,Ifi211,Foxp4,Klf8,Bcor,Prdx5,Hat1,Nfkbie,Hcls1,Jarid2,Ccne1,Ifi203,Stat3,Src,Nr3c1,Gbp4,Znfx1,Ifi208,Parp9,Pdgfb,Gclc,Txn1,Parp3,Junb,Ednrb,Ppp1r15a,Ifi214,Arid5b,Max,Bcl6,Egr1,Jdp2,Zhx2,Notch2,Eno1,Dr1,Dnajb4,Larp1,Rbl1,Mtdh,Kmt5a,Arid5a,Ago3,Pml,Ifi207,Atf3,Phf6,Ikzf1,Met,Mafk,Acvrl1,Prdm1,Mxd1,Nck1,Zfp281,Mdfic,Daxx,Ifi204,Tnf,Plk3,Fzd1,Jun,Tcf4,Gfpt1,Cited2,Hmga2,Hhex,Il1b,Irf8,Trib3,Sirt1,Etv3,Klf3,Btg2,Rfx5,Mdm2,Nr4a3,Psmd10,Cdk5r1,Ccnd1,Ahr,Ifi209,Relb,Nfkb1,Klf7,Zmynd15,Cav1,Ptch1,Gja1,Ifi205,Sqstm1,Bmp2,Zbtb5,Rel,Dusp5,Nmral1,Mier3,Timeless,Cd38,Cpeb4,Ifi213,Ahrr,Sap30,Ciita,Hif1a,Dusp1,Kdm4a,Nfil3 |
| 2.946e-07 | -15.04 | nuclear lumen | cellular component | GO:0031981 | 3432 | 303 | 20747 | 1409 |
Rpgrip1l,Spire1,Ell2,Plscr1,Uchl1,Setdb2,Tap2,Psme2,Stxbp1,Actb,Mdfic,Casp8,Parp10,Plekhg1,Trim21,Pbx1,Sinhcaf,Kdm4a,Ifi211,Mxd1,Ccne1,Lap3,Gbp2,H3f3b,Tcea1,Pfkfb3,Ifi203,Oas3,Mppe1,Ifi208,Hmga2,Serpinb9,Parp9,Sqstm1,Gja1,Ep400,Kat2b,Rbbp8,Psma6,Ago3,Tut7,Lnpk,Dock4,Slc44a1,Rsad2,Ifi205,Sertad3,Ccnd2,Relb,Ccnd1,Stat3,Etv6,Cenpe,Hilpda,Hspa1a,Oasl1,Cdkn2d,Med13,Ikbke,Mcmbp,Vezt,Hif1a,Ezr,Dennd1b,Smox,Daxx,Pim1,Stat5a,Nfkbie,Nek6,Med21,Phlpp1,Hck,Adar,Rgs14,Gpc1,Timeless,Stat1,N4bp1,Stx6,Phf11d,Hmox1,Arid4a,Rel,Itpkc,Shfl,Olr1,Rbpms,Spen,Rilpl1,Riox2,Plagl1,Mcm10,Mdm2,Tent4a,Rars,Mier3,Cacybp,Hat1,Ahrr,Oas1g,Notch2,Smc5,Slc9a1,Tnip1,Bcl6,Arl4a,Trip10,Oas1a,Socs1,Ets2,Max,Dock10,Birc3,Aldh1b1,Psme1,Ifi213,Mcm6,Aebp2,Hinfp,Isg20,Anp32a,Dusp4,Prdm9,Rabgef1,Hivep2,Golga3,Carmil1,Nfkb1,Morc3,Zhx2,Dusp16,Mtdh,Malt1,Ptk2,Htr2b,Polr2g,Sirt1,Klf8,Syne2,Junb,Mafk,Ccdc86,Bnip3,Clic4,P4ha2,Noc4l,Psmb6,Etnk1,Fam111a,Cdyl,Cx3cr1,Klf2,Mdn1,Il15,Zeb1,Cyth3,Jun,Irf1,Rapgef5,Ifi214,Oasl2,Clcn7,Cdk5r1,Phlda1,Dcp2,Rbl1,Tle3,Mpp7,Trib3,Cnp,Wdr43,Pml,Tasor2,Batf,Rcl1,Dse,Fos,Kdm5b,Dr1,Ptpn2,Pou2f2,Oas2,Agtrap,Prdx1,Mtus1,Hspa2,Atm,Rrs1,Tma16,Top3a,Vps54,Gch1,Dtx2,Hsph1,Abtb2,Maml2,Egr1,Ifi204,Dtx3l,Nxf1,Bcorl1,Irf8,Rgcc,Ciita,Phf11c,Jak2,Txnrd1,Asf1a,Egr2,Sap30,Kdm6b,Dyrk2,Stk40,Jmjd6,Plekha5,Snapc1,Upp1,Tcf4,Phf11a,Etv5,Ctsc,Sp100,Ikzf1,Stap1,Sh3bgrl2,Phf11b,Keap1,Mark2,Aff1,Cdkn1a,Fosb,Alas1,Gfi1,Atf3,Nr1h3,Spata13,Etv3,Hdac1,Psip1,Prpf4,Acsl5,Oas1b,Pdk3,Ubr4,Crbn,Zc3h12a,Jarid2,Tpx2,Ier2,Tulp3,Phf6,Nr3c1,Myo10,Zfp281,Nfkbiz,Cutc,Sik3,Asap3,Bbx,Casz1,Cebpd,Myc,Mndal,Aim2,Brd2,Klf6,Ifi207,Higd1a,Mapkapk2,Sp140,Ciapin1,Itpr1,Rai14,Eef1e1,Taf4b,Klf3,Fas,Cited2,Tfec,Gsdmd,Irf7,Tnks1bp1,Arid5a,Nmi,Tra2a,Fubp1,Cenpj,Samhd1,Pcgf5,Irf2,Ifi209,Irf4,Dnajb4,Nampt,Sbds,Mecp2,Ppp4r2,Parp3,Rnf34,Crkl,Plk3,Rgs3 |
| 2.958e-07 | -15.03 | GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_UP | MSigDB lists | GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_UP | 159 | 33 | 15632 | 1249 |
Il15,Cd80,Atp2b4,Itga4,Prdm1,Slco3a1,Fcgr2b,Cish,Spn,Cx3cr1,Pik3r5,Cyfip1,Ttc39c,Cmklr1,Osbpl3,Rgs1,Clic4,Rnf19b,Dgkh,Ptprj,Kif5c,Ell2,Ttc39b,Smpdl3b,Il18rap,Slc4a7,Snx10,Myadm,Ccl5,Tnfrsf1b,Hopx,Itgal,Gna15 |
| 2.958e-07 | -15.03 | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN | MSigDB lists | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN | 159 | 33 | 15632 | 1249 |
Atp2b4,Cd38,Slamf7,Pttg1,Tpx2,Prdm1,Tpi1,Cox17,Chst11,Fgl2,Cpd,Swap70,Plac8,Cenpe,Cx3cr1,Casp1,Insl6,Osbpl3,Ccl4,Serpinb9,Ptprj,Smpdl3b,Rap1gap2,Hk2,Il18rap,Sap30,Hopx,Itgal,Gem,Plek,S100a8,Snx10,Myadm |
| 2.979e-07 | -15.03 | ion homeostasis | biological process | GO:0050801 | 793 | 92 | 20694 | 1406 |
Lpar1,Mafg,Cxcl10,Scn1b,Ero1l,Tmem178,1600014C10Rik,Lcn2,Fpr2,Hap1,Xcr1,Snx10,Src,Gpr18,Hmox1,Cxcl3,Jak2,Slc31a1,Marcksl1,Swap70,Tspo,Cxcl1,Cmklr1,Atp2b4,Ptger4,Sco1,Cx3cr1,Mllt6,Ccl2,Slc9a1,Slamf8,Slc30a1,Adrb2,Ccrl2,Edn1,Ptgir,Ccr3,Ptk2,Slc12a9,Gclm,Myc,Htr2a,Gna15,Rmdn3,Hif1a,Prnp,Cd38,Mt1,Slc39a13,Cacnb3,Dmxl2,Prkce,Slc31a2,Cav1,Slc7a11,Itgav,Itpr1,Slc39a4,Htr2b,Gja1,Slc30a4,Tmtc2,Il1b,Slc39a14,Grina,Sirt1,Cx3cl1,Mt2,P2ry2,Ccl3,Sod2,Cacna1d,Kdr,Cp,Pml,Ccr1,Rab20,Gpr35,Ccl5,Cxcl2,Nox1,Cutc,Clic4,Atp13a1,Cd40,Gclc,Fabp3,Ednrb,Slc4a7,Fpr1,Bnip3,Lipg |
| 3.000e-07 | -15.02 | Schlafen_AlbA_2_dom_sf | interpro domains | IPR038461 | 9 | 7 | 19984 | 1430 |
Slfn4,Slfn1,Slfn9,Slfn5,Slfn3,Slfn2,Slfn8 |
| 3.000e-07 | -15.02 | Schlafen | interpro domains | IPR029684 | 9 | 7 | 19984 | 1430 |
Slfn8,Slfn2,Slfn3,Slfn5,Slfn1,Slfn9,Slfn4 |
| 3.000e-07 | -15.02 | Schlafen_AlbA_2_dom | interpro domains | IPR007421 | 9 | 7 | 19984 | 1430 |
Slfn5,Slfn8,Slfn3,Slfn2,Slfn1,Slfn4,Slfn9 |
| 3.027e-07 | -15.01 | GO_HEMOSTASIS | MSigDB lists | GO_HEMOSTASIS | 304 | 51 | 15632 | 1249 |
Cd40,P2ry12,Itpr1,Axl,Src,Ehd1,Mafk,Hdac1,Irf2,Ifna2,Pdgfc,Pik3r6,Lcp2,Csrp1,Plek,Dgka,Adora2a,Maff,Ifna6,Stxbp3,Pf4,Plaur,Plat,Syk,Slc7a11,Pik3r5,Ifnb1,Ifna5,Ap3b1,Prkce,Pdpn,Il6,Cx3cl1,Papss2,Stxbp1,Enpp4,Plau,F10,Ifna1,Gna15,Plscr1,Procr,Lyn,Mafg,Irf1,C3,Dgkh,Prkar2b,H3f3b,Jak2,Actb |
| 3.029e-07 | -15.01 | cellular metabolic process | biological process | GO:0044237 | 6428 | 522 | 20694 | 1406 |
Gch1,Serp1,Rcl1,Psat1,Myd88,Met,Irgm1,Me1,Mdfic,Magohb,Gfpt1,Phlpp2,Plaat3,Egr2,Kdr,Setdb2,Ubash3b,Cnot4,Kdm6b,Cgas,Plod2,Mark2,Ppp1r15a,Dusp4,Plod3,Egr1,Zhx2,Calcrl,Hmgcs1,Ext1,Fut8,Ube2e2,Kmt5a,Samhd1,Ctsc,Ubr4,Fbxo4,Prnp,Slfn8,Grk3,Prdm9,Thbs1,Plk2,Dusp8,Sap30,Ciita,Hif1a,Ccnd2,Kdm4a,Hmga2,Ppp2r3a,Tmtc2,Dtx2,Dram1,Mppe1,Mapkapk2,Pttg1,Extl2,Mdm2,Slc7a2,Nr4a3,Ccnd1,Pcx,Il4i1,Alas1,Cemip2,Itgav,Hk2,Scyl2,Glrx,Ddit4,St3gal1,Ezr,Parp14,Dio2,Pgs1,Tlr9,Parp8,Ell2,Hopx,Trim12a,Znrf3,Dcun1d3,Mecp2,Usp31,Kmo,Ppp4r2,Rnf19b,Dcp1a,Pde5a,Myc,Aff1,Dusp16,Ppa1,Birc2,Ifih1,Pde1b,Ampd3,Tapbp,Tpst1,Hck,Stat3,Parp12,Src,Itpkc,Rbms1,Tnks1bp1,Smpdl3b,Fam111a,Ikbke,Phyh,Ptafr,Ak4,Pdgfb,P4ha2,Ero1l,Ranbp2,Mcm6,Hk3,Mthfd1l,Swap70,Dnase1l3,Optn,Mcm10,Ripk3,Adar,Il12rb1,Cycs,Trib1,Stat1,Usp35,Bcor,Prdx5,Hat1,Pim2,Zc3h12c,Ago3,Ccnj,Eya4,Pml,Ciapin1,Noct,Col4a2,Bfar,Trim36,Sod2,Agpat4,Syk,Stat4,Smox,C3,Cd74,Dusp28,Junb,Prpf4,Malt1,Psmb6,Oas2,Rnf31,Ccl5,Srm,Cdkn2d,Nox1,Wars,Igf1r,Larp1,Psip1,Vrk2,Fgr,Map3k6,Dusp2,Isg20,Cdyl,Degs2,Timeless,Sat1,Ahrr,Ankib1,Minpp1,Fos,Rnaset2b,Acsl1,Tent4a,Atm,Upp1,Axl,Irf8,Acsl5,Txnrd1,Trim13,Arf4,Fam20c,Parp11,Ahr,Slc7a11,Tnip1,Chst11,Lyn,Htr2b,Lmo4,Helz2,Usp18,Acvr1,Hinfp,S100a8,Gbgt1,Yju2,Hdac1,Egln3,Mmp13,Mov10,Ptger4,Hdc,Tgs1,Dhrs9,Enpp4,Itgb8,Morc3,Cop1,Zfp36,Irak3,Sgms2,Pla2g7,Carmil1,Xrn1,Trim21,Tent2,Ass1,Aoah,Ptprj,Tlk2,Nmi,Cmpk2,Gcnt2,Icosl,Dyrk2,Asns,Trmt1l,Map4k4,Endod1,Smc5,Nos2,Irgm2,Parp9,Mcmbp,1600014C10Rik,Irak2,Tiparp,Hmox1,Tlr2,Pim1,Plpp1,Lipe,Gsta3,Vcpip1,Znrf1,Uba7,Pla2g4a,Gys1,Rbbp8,Trim56,Pikfyve,Casp8,Denr,Nampt,Eno2,Acvrl1,Rnf19a,Mthfd2,Fnbp1l,Nck1,Inpp5b,Rffl,Sik3,Dusp6,Agrn,Tha1,Tra2a,Psmb10,Bnip3,Mtfr2,Tmem67,Bmp2,Dck,Plek,Ube2l6,Cpeb4,Phgdh,Lox,Saa3,Otud1,Mcm9,Acvr1b,Dusp1,Pgap2,Isg15,Pim3,Sla,Il1b,Acp2,Polr2g,Tet2,Trib3,Acp5,St3gal5,Btg2,Mlkl,Keap1,Cdk5r1,Prkce,Ppp2r5a,Ppm1l,Tlr3,Psmb8,Birc3,Batf,Cept1,Arrdc4,Dcp2,Gtpbp2,Psmb9,Med21,Pnpt1,Eif2ak2,Pdpn,Socs1,Ascc3,Stat5a,Ppm1k,Map3k8,Socs3,Arid4a,Inpp1,Rnf34,Apobec3,Slfn9,Herc6,Eef1e1,Nr1h3,Prag1,Gbe1,Prkx,Fosb,Kdm5b,Gda,Ptk2,Slc25a22,Pdgfrb,Ptpn2,Gsr,Il15,Nupr1,Dnajb2,Snapc1,Zc3h7a,Ccng2,Rhoq,Dusp14,Dgkh,Map2k1,Pdk3,Trim12c,Eif4g2,Odc1,Phlda1,Peli1,Nr3c1,Psma6,Wdr43,Dpy19l1,Gpc1,Ube2e1,Arg2,Oas1a,Flt1,Usp12,Lif,Slc25a25,Pdss1,Akt3,Rnf139,Spsb1,Tyk2,Ptges,Rictor,Pgk1,Inhba,Tnfaip3,Jak2,Tlr6,Tcea1,Sphk1,Armc8,Asah2,Acpp,St3gal6,Taf4b,Cpd,Parp10,Ccl12,Caml,Angpt1,Prpf38a,Dse,Prdx1,Etnk1,Tnf,Plk3,Mapkbp1,Tcf4,Pcgf5,Jun,Rnf135,Gclc,Nt5c3,Lpcat2,Parp3,P4ha1,Nqo1,Slc25a12,Lipg,Hk1,Kat2b,Jmjd6,Uchl1,Dr1,Pfkl,Ppp2r2a,Marf1,Mrpl52,Tpi1,Sde2,Dusp5,Plscr1,Ldha,Pik3cd,Mgat1,Ptgs2,Oasl2,Ksr1,Mmd,Ddx4,Nfil3,Sirt1,Arel1,Plcl2,Ctu1,Trim30a,Adhfe1,St3gal3,Osm,Cav1,Acod1,Sqstm1,Map2k4,Ppp1r15b,Asf1a,Il10,Cnp,Pigv,Gk,Klhl25,Rars,Phlpp1,Naa25,Usp42,Hspa1a,Plpp3,Ccr3,Med13,Sgk3,Mtmr14,Cers6,Usb1,Irf4,Ep400,Lnpep,Dtx3l,Gclm,Rubcnl,Ube2f,Esd,Nsd3,Papss2,Hmga1,Cish,Edn1,Prkar2b,Trip13,Socs7,Rnaset2a,Rrs1,Dgka,Idi1,Smg7,Ldlr,Jarid2,Ccne1,Hap1,Hivep2,Tut7,B3gnt5,Pfkfb3,Rnf14,Gpd2,Stk40,Lrp4,Ripk2,Mul1,Mthfr,Traf2,Nek6,Usp25,Mocs1,Chmp4b,Il18,Mdn1,Zc3h12a,Usp53,Top3a,Sbds,Crbn |
| 3.046e-07 | -15.00 | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_DN | MSigDB lists | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_DN | 182 | 36 | 15632 | 1249 |
Prdx5,Dusp4,Il6,Rffl,Slc15a3,Ccdc86,Spry2,Micall2,Edn1,Hmga1,Slc2a1,Klhl25,Ppp1r14b,Nfkbia,Tnfaip3,Klf7,Gys1,Plau,Upp1,Fpr2,Mxd1,Maff,Car13,Atxn7l1,Slc7a5,Hopx,Ppp1r15b,Hcar2,Il15ra,Bambi,Pdzd11,Mafg,Sema4a,Trib3,Ldha,Uaca |
| 3.046e-07 | -15.00 | GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN | MSigDB lists | GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN | 182 | 36 | 15632 | 1249 |
Ifit1,Crlf3,Psme1,Lrp8,Cebpd,Slc44a1,Mrpl52,Gpr18,Rab32,Trafd1,Pf4,Tnfsf10,Cd82,Serpinb2,Nfkb2,Irak2,Smox,Ifi35,Ppa1,Denr,Stat4,Rapgef2,Rasgrp1,Spint2,Pde7b,Spen,Slc2a6,Psme2,Plscr1,Tap2,Fosb,Pik3r6,Casp4,Gbp7,Ahrr,Hk1 |
| 3.046e-07 | -15.00 | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | 182 | 36 | 15632 | 1249 |
Zfp36,Kctd12,Dusp6,Fosb,Lmo4,Znrf1,Dnajb2,Rcl1,Pim2,Socs3,Larp1,Adrb2,Pim1,Odc1,Tnfsf8,Slc44a1,Myc,Atp13a1,Tapbp,Parp8,Dusp1,Klf6,Jun,Ets2,Fos,Notch1,Mcoln2,Tlr6,Nfkbiz,Evl,Traf1,Sell,Slc30a1,Il4ra,Ccnd2,Prnp |
| 3.046e-07 | -15.00 | GO_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 102 | 25 | 15632 | 1249 |
Hlx,Abr,H2-Q7,Il4ra,Mul1,Angpt1,Irak3,Tap1,H2-Q4,Tnf,Ifit1bl1,Spn,Eif2ak2,H2-Q6,Bcl6,Dhx58,Ifnb1,Tnfsf4,Cd55,Hmox1,Serpinb9,Ifit1bl2,Rabgef1,Il10,Htra1 |
| 3.089e-07 | -14.99 | homeostasis of number of cells | biological process | GO:0048872 | 258 | 41 | 20694 | 1406 |
Stat5a,Tmod3,Cited2,Il6,Arid4a,Hif1a,Dock10,Hcls1,Ampd3,Prdx1,Pik3cd,Bcl2l11,Ccl2,Ikzf1,Bcl2a1a,Jmjd6,Lyn,Tnfaip3,Ripk3,Fas,Hcar2,Hmox1,Csf1,Adar,Ahr,Klf2,Tcea1,Ikbkg,Casp3,Prdx5,Jak2,Axl,Tet2,Pmaip1,Akt3,Notch1,Rac3,Pde4b,Vps54,Bcl6,Ptpn2 |
| 3.119e-07 | -14.98 | MEL18_DN.V1_UP | MSigDB lists | MEL18_DN.V1_UP | 130 | 29 | 15632 | 1249 |
Zc3h12a,Itga5,Vegfc,Plaur,Tfec,Pmepa1,Adam19,Plat,Inhba,Jag1,Nrp2,Csf1,Ddit4,Slc2a6,Slc7a5,Piezo1,H2-Aa,Itga4,Lif,Tap1,Cd83,Tnfrsf8,Slc7a11,Abcc5,Agrn,Ccnd1,Chst11,Edn1,Itgb8 |
| 3.123e-07 | -14.98 | MODULE_12 | MSigDB lists | MODULE_12 | 330 | 54 | 15632 | 1249 |
Ccnd2,Cx3cl1,Me1,Nr4a1,Cx3cr1,Ifit1bl1,Ccl12,Fos,Tspan3,Zyx,Il6,Vcan,Kif5c,Tnfaip2,Rgs1,Ldlr,Cdkn1a,Dnajb2,S100a8,Eno2,Ednrb,Tnfrsf1b,Cav1,Lmo4,Zeb1,Fabp7,Cnn3,Slpi,St3gal5,Nupr1,Isg15,Cd14,Crim1,Tnfaip3,Mtus1,Bcl6,Tnc,Ccnd1,Hspa2,Rtn1,Tgfbi,Lox,Cxcl1,Gng12,Junb,Nampt,Pde4b,Ifit1bl2,Gja1,Hopx,Cnp,Fosb,Serpine1,Ddit4 |
| 3.123e-07 | -14.98 | response to abiotic stimulus | biological process | GO:0009628 | 1000 | 110 | 20694 | 1406 |
Mdm2,Lrrc8c,Sirt1,Pmaip1,Plat,Casp3,Htr2b,Itpr1,Gja1,Cav1,Osm,Nfkb1,Slc7a11,Relb,Ccnd1,Prkce,Cpeb4,Thbs1,Cd38,Cacnb3,N4bp1,Fbxo4,Hspa1b,Tank,Sde2,Bmp2,Cyfip1,Atm,Ccnd2,Higd1a,Hif1a,Fos,Cnn2,Ptgs2,Bnip3,Pde4b,Actb,Junb,Txn1,Il12b,Gclc,Psip1,Nox1,Cdkn2d,Egr1,Rgcc,Cdkn1a,Pml,Cited2,Kdr,Jun,Rcsd1,Sod2,Fam162a,Plk3,Tnf,Il1a,Daxx,Plac8,Il18,Rgs14,Trip10,Gfi1,Notch1,Uaca,Lrp11,Stat1,Pgk1,Usp53,Vasn,Hmox1,Gpr68,Tnks1bp1,Tfec,Casp1,Pdk3,Tlk2,Ak4,Flt1,Nos2,Piezo1,Dnaja2,Myc,Htr2a,Cop1,Kmo,Casp7,Pde1b,Hspa2,Dnaja1,Edn1,Birc2,Hvcn1,Fas,Clcn7,Slc9a1,Adrb2,Nfkbia,Ccl2,Plau,Dio2,Ddit4,Mecp2,Vegfc,Ptger4,Dcun1d3,Atp2b4,Plekhn1,Rnf34,Hspa1a |
| 3.140e-07 | -14.97 | AlbA_2 | pfam domains | PF04326 | 9 | 7 | 18711 | 1348 |
Slfn3,Slfn2,Slfn5,Slfn9,Slfn1,Slfn4,Slfn8 |
| 3.140e-07 | -14.97 | TNF-alpha NF-kB Signaling Pathway | WikiPathways | WP246 | 181 | 44 | 4813 | 540 |
Mark2,G3bp2,Pml,Kpna3,Nfkbib,Hdac1,Traf1,Map3k8,Tnip1,Azi2,Casp3,Birc2,Relb,Casp8,Casp7,Tnf,Tnfrsf8,Traf5,Nfkbia,Nsmaf,Stat1,Ptk2,Birc3,Nfkbiz,Traf2,Cflar,Tab2,Tank,Src,Nfkb2,Ripk3,Ripk2,Cav1,Tnfrsf1b,Ikbkg,Nkiras1,Rel,Tnfaip3,Nfkbie,Nfkb1,Ktn1,Tifa,Ikbke,Casp2 |
| 3.156e-07 | -14.97 | GSE43955_1H_VS_42H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_1H_VS_42H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 190 | 37 | 15632 | 1249 |
Ddx4,Kcna3,Il13ra1,Il15ra,Fam162a,Igf1r,Serpinb2,Nos2,Zc3h12c,Il10,Nfkb1,Slc7a8,Hk2,Hivep3,Trip13,Noc4l,Flnb,Ifih1,Hif1a,Pttg1,Prnp,Tmem176b,Me1,Rgs3,Tal2,Fcgr1,Pim3,Dnaja1,Tagln,Itgav,Plac8,Dtnb,Rsad2,Dbnl,Cp,Ccr3,Tor1aip2 |
| 3.180e-07 | -14.96 | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | MSigDB lists | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | 246 | 44 | 15632 | 1249 |
Phlda1,Stx11,Degs2,Map4k4,Slc4a7,Plk2,Flrt2,Zhx2,Snn,Hmox1,Ptgs2,Tgfbi,Fchsd2,Rab11fip1,Gsr,Kdm5b,Mafk,N4bp1,Klf6,Csrnp1,Mxd1,Med13,Slpi,Dcun1d3,Cep350,Sema3c,Pmepa1,Abcc1,Esd,Ell2,Hmgcs1,Cpeb4,Odc1,Pdpn,Flrt3,Klf3,Tiparp,Fos,Cd80,Samhd1,Lrp8,Irs2,Spred3,Ubash3b |
| 3.186e-07 | -14.96 | GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 123 | 28 | 15632 | 1249 |
Dusp16,Prkar2b,Il1b,Cdkn1a,Aida,Lyn,Ptprj,Uchl1,Dusp5,Sirt1,Cav1,Dusp6,Rgs3,Spred1,Irak3,Dusp14,Tnfaip3,Kat2b,Hhex,Cdkn2d,Dusp4,Spry2,Casp3,Dusp8,Dusp2,Rgs14,Dnaja1,Dusp1 |
| 3.282e-07 | -14.93 | response to oxygen levels | biological process | GO:0070482 | 268 | 42 | 20694 | 1406 |
Plau,Adrb2,Cpeb4,Slc9a1,Cd38,Pdk3,Bmp2,Ddit4,Casp1,Pml,Hif1a,Plekhn1,Flt1,Kdr,Higd1a,Vegfc,Ak4,Cited2,Mecp2,Atm,Nos2,Plk3,Sod2,Fam162a,Sirt1,Il18,Myc,Bnip3,Notch1,Birc2,Edn1,Nox1,Itpr1,Plat,Prkce,Vasn,Hmox1,Rgcc,Fas,Egr1,Cav1,Pgk1 |
| 3.283e-07 | -14.93 | receptor signaling pathway via JAK-STAT | biological process | GO:0007259 | 36 | 13 | 20694 | 1406 |
Stat4,Lif,Jak2,Stat1,Stat3,Socs3,Il15ra,Stat2,Stat5a,Osm,Socs1,Il15,Clcf1 |
| 3.293e-07 | -14.93 | GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | MSigDB lists | GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION | 383 | 60 | 15632 | 1249 |
Spred1,Angpt1,Mul1,Ppm1l,Irs2,Mapkapk2,Nod2,Dusp4,Myc,Psmd10,Map3k6,Itgav,Syk,Ccl12,Jak2,Kdr,Acvr1b,Trib1,Map2k4,Lyn,Ptk2,Rasgrp1,Ksr1,Psme2,Cav1,Psmb8,Nfkb1,Ikbkg,Daxx,Mdfic,Nod1,Tab2,Psmb10,Psme1,Acvr1,Psma6,Acvrl1,Dbnl,Psmb9,Tnf,Il1b,Htr2b,Irak2,Kitl,Adora2b,Map3k8,Il2rg,Il18,Crkl,Ptger4,Psmb6,Dusp5,Ripk2,Rapgef2,Pdgfb,Map2k1,Pdgfrb,Ccl5,Map4k4,Dusp6 |
| 3.307e-07 | -14.92 | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | 64 | 19 | 15632 | 1249 |
Ldlr,Slamf7,Gfpt1,Cflar,Nfil3,Tnfaip3,Cd38,Ell2,Dusp5,Pim2,Prdm1,Atf3,Zfp36,Irf4,Casp3,Apobec3,Nampt,Nr4a1,Cav1 |
| 3.315e-07 | -14.92 | cellular response to organonitrogen compound | biological process | GO:0071417 | 510 | 66 | 20694 | 1406 |
Larp1,Igf1r,Socs7,Vcam1,Rhoq,Phip,Nod1,Irs2,Kat2b,Nod2,Icam1,Egr1,Rab10,Itga4,Pde4b,Actb,Ptpn2,Ptk2,Casp7,Zeb1,Atp2b4,Pde3b,Sh3bp4,Mecp2,Stat5a,P2ry12,Tnf,Socs1,Tlr9,Adrb2,Slc9a1,Irf1,Agtrap,Ezr,Fcgr2b,Nr4a1,Jak2,Casp3,Tlr6,Stat1,Itpr1,Htr2b,Nfkb1,Cav1,Tlr2,Nr4a3,Ahr,Mdm2,Sirt1,Il18,Pdgfc,Akt3,Trib3,Nlrp3,Cyfip1,Sesn3,Ripk2,Casp4,Cpeb4,Rapgef2,Timeless,Src,Stat3,Prnp,Nmral1,Fpr2 |
| 3.358e-07 | -14.91 | RAF_UP.V1_UP | MSigDB lists | RAF_UP.V1_UP | 175 | 35 | 15632 | 1249 |
Syne2,Kctd12,Slc2a6,Alas1,Nmi,Fzd5,Ccr1,S100a8,Slc31a2,Glrx,Abcc4,Rcan1,Phyh,Nr4a3,Acsl1,Ptger4,Arhgap26,Optn,Hspa2,Dusp4,Cebpd,Rsad2,Sat1,Gclm,Fchsd2,Arhgef3,Psmb9,Klf6,Crim1,Etv5,Rras2,Kat2b,Upp1,Psmb10,Malt1 |
| 3.358e-07 | -14.91 | GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP | 175 | 35 | 15632 | 1249 |
Ifit1bl2,Tuba4a,Ppp1r15a,Cacybp,Zc3h7a,Zeb1,Rnf19a,Chic2,Pik3cd,Bcl2a1a,Tax1bp1,Esd,Sec24b,Ifit1bl1,Ifit2,Crbn,Bcl2a1b,Dnaja1,Tor1aip2,1110038F14Rik,Stap1,Gpr35,Taf4b,Cept1,Bcl2a1d,Dock10,Psme1,Tmem176b,Kat2b,Ifih1,Ppm1l,Nxf1,Hvcn1,Daxx,Prpf38a |
| 3.378e-07 | -14.90 | GSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_UP | MSigDB lists | GSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_UP | 145 | 31 | 15632 | 1249 |
Trip10,Bcl6,Spic,Klf3,Fchsd2,Rab21,Parp14,Gpr141,Kmo,Klf8,Lrch3,Slc30a4,Casp8,Lcn2,Psmb8,Pde4b,Cdyl,Syne2,Zscan29,Bcl9,Gpd2,Il2rg,Tmem229b,Phyh,Parp3,Ell2,Cd55,Mtmr14,Nfil3,Adam19,Acsl5 |
| 3.411e-07 | -14.89 | response to wounding | biological process | GO:0009611 | 376 | 53 | 20694 | 1406 |
Cx3cl1,Pdpn,Ap3b1,Il1a,Jun,P2ry12,Sod2,Stxbp1,Lnpk,Tnc,Ubash3b,Sdc4,Map2k4,Cdkn1a,Acvrl1,Plau,Ccl2,Pf4,Adrb2,Evl,Dcbld2,Notch2,Papss2,Stxbp3,Serpinb2,Ifrd1,Enpp4,C3,Zfp36,Cnn2,Lox,Bcl9,Cflar,Hif1a,Il6,Dst,Pdgfb,Ptprj,Map2k1,F10,Plek,Sdc1,Hmox1,Cav1,Tnfaip3,Slc7a11,Timp1,Gja1,Flrt3,Casp3,Jak2,Axl,Procr |
| 3.446e-07 | -14.88 | GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | MSigDB lists | GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | 160 | 33 | 15632 | 1249 |
Rabgef1,Jarid2,Irf8,Lmo4,Trim26,Wdr59,Akt3,Hivep3,Egln3,Sema4c,Cd200,Filip1l,Pik3cd,Acsl1,Gfpt1,Fam102b,Cflar,Rpgrip1l,Slc37a3,P4ha2,Klhl25,Homer1,Phlpp1,Arhgap26,Cers6,Malt1,Kmo,Slco3a1,Ppm1l,Sell,Cdk5r1,Herc3,Sla |
| 3.449e-07 | -14.88 | KEGG_PATHWAYS_IN_CANCER | MSigDB lists | KEGG_PATHWAYS_IN_CANCER | 331 | 54 | 15632 | 1249 |
Pdgfb,Fzd1,Fzd5,Pdgfrb,Map2k1,Ralgds,Nfkb2,Kitl,Vegfc,Crkl,Ptgs2,Cycs,Stat3,Casp3,Ccnd1,Mdm2,Hdac1,Stat5a,Traf2,Slc2a1,Birc2,Csf3r,Traf5,Bmp2,Pml,Hif1a,Traf1,Akt3,Egln3,Met,Birc3,Ikbkg,Ccne1,Nfkb1,Ptch1,Casp8,Nos2,Igf1r,Cdkn1a,Ptk2,Max,Rac3,Mmp9,Stat1,Pik3cd,Il6,Myc,Nfkbia,Pik3r5,Itgav,Fos,Jun,Col4a2,Fas |
| 3.463e-07 | -14.88 | Poly(ADP-ribose)pol_cat_dom | interpro domains | IPR012317 | 16 | 9 | 19984 | 1430 |
Parp9,Parp3,Parp8,Parp14,Parp11,Tiparp,Zc3hav1,Parp10,Parp12 |
| 3.463e-07 | -14.88 | Chemokine_CC_CS | interpro domains | IPR000827 | 16 | 9 | 19984 | 1430 |
Ccl12,Ccl9,Ccl4,Ccl8,Ccl7,Ccl3,Ccl2,Ccl5,Ccl22 |
| 3.496e-07 | -14.87 | PID_IL6_7_PATHWAY | MSigDB lists | PID_IL6_7_PATHWAY | 47 | 16 | 15632 | 1249 |
Hck,Jak2,Map2k4,Irf1,Socs3,Stat1,Cebpd,Tyk2,Il6,Myc,Stat3,Jun,Lmo4,Fos,Timp1,Junb |
| 3.506e-07 | -14.86 | GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP | 183 | 36 | 15632 | 1249 |
Phldb1,Plekha5,Bcl2a1b,Cx3cr1,Gsdmd,Psmb9,Tbc1d1,Bcl2a1d,Ccnd1,Csrnp1,Evl,Prdm1,Fpr2,Rras2,Gnb4,Tap1,Hck,Jarid2,Cd86,Icosl,Vasp,Slamf9,Usp12,Rtn1,Ptk2,Dgkh,Pik3cd,Rnf145,Irak2,Bcl2a1a,Dek,Vrk2,Ap3m2,Ppfibp2,Slc37a3,Fmnl2 |
| 3.506e-07 | -14.86 | GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_DN | 183 | 36 | 15632 | 1249 |
Bcl6,Trip10,Hsph1,Tnf,Dusp4,Fchsd2,Cish,Tnfsf8,Tbc1d1,Irf4,Casp3,Slco3a1,Socs1,Etv3,Rab19,Nfkbiz,Batf,Lcp2,Rel,Csrp1,Pde4b,Cd69,Spint2,Tbc1d13,Stat4,Gpr132,Csf1,Ttc39b,Ell2,Etnk1,Trafd1,Gfi1,Slc37a3,Rgs1,Adam19,Fam102b |
| 3.506e-07 | -14.86 | GSE17721_4_VS_24H_CPG_BMDC_UP | MSigDB lists | GSE17721_4_VS_24H_CPG_BMDC_UP | 183 | 36 | 15632 | 1249 |
Parp12,Eya4,Noc4l,Bcl9,Nfkb1,Ccr1,Rabgef1,Frmd6,Xcr1,Snn,Prkx,Rbms1,Il18,Map2k4,Slc25a22,Cox18,Osgin2,Lpar1,Hmgcs1,Rab9,Katna1,Edn1,Sbds,Ifnar1,Rhoc,Traf5,Rras2,Sav1,F10,Bfar,Arl4a,P2ry14,Xrn1,Fabp3,Tlr6,Nck1 |
| 3.506e-07 | -14.86 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP | 183 | 36 | 15632 | 1249 |
Bcl2a1a,Dusp16,Lacc1,Pim2,Ell2,Adora2b,Ahrr,Il10,Vezt,Sco1,Irf8,Pde3b,Dusp14,Vcpip1,Ahr,Notch1,Cd38,Ifit1,Atf3,Prdm1,Slc39a4,Casp3,Cpd,Bcl2a1d,Chst11,Cdyl2,Bcl2a1b,Gadd45b,Plac8,Ehd1,Hspa1a,Mgat1,Acpp,Arid5a,Tspan3,Ttc39c |
| 3.529e-07 | -14.86 | GO_POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION | 96 | 24 | 15632 | 1249 |
Il6,Pnp2,H2-Q6,Syk,Spn,H2-Q4,Cd80,Ccdc88b,Il15,Nck1,H2-Q7,Il12rb1,Icosl,Cd86,Cd274,Ccl5,Il1b,Vcam1,Il18,Il12b,Ripk2,Cd55,Tnfsf4,Ebi3 |
| 3.529e-07 | -14.86 | GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | 96 | 24 | 15632 | 1249 |
Ptafr,Nr4a3,Il12b,Ptgs2,Trib1,Ptgir,Hmox1,Stat1,Nox1,Pdgfb,Pdgfrb,Cav1,Ccl5,Nampt,Tnfaip3,Il15,Cx3cl1,Calcrl,Hif1a,Il6,Edn1,Jun,Tnf,Flt1 |
| 3.602e-07 | -14.84 | GO_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | 27 | 12 | 15632 | 1249 |
Il12rb1,Il6,Cd86,Cd80,Cd83,Il4ra,Nlrp3,Il12b,Ripk2,Cd55,Hlx,Tnfsf4 |
| 3.617e-07 | -14.83 | KEGG_SMALL_CELL_LUNG_CANCER | MSigDB lists | KEGG_SMALL_CELL_LUNG_CANCER | 83 | 22 | 15632 | 1249 |
Nos2,Ccne1,Nfkb1,Ikbkg,Birc3,Akt3,Pik3cd,Ptgs2,Max,Ptk2,Birc2,Traf2,Itgav,Pik3r5,Nfkbia,Ccnd1,Myc,Cycs,Traf1,Apaf1,Col4a2,Traf5 |
| 3.619e-07 | -14.83 | GSE9650_NAIVE_VS_EFF_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_EFF_CD8_TCELL_DN | 191 | 37 | 15632 | 1249 |
Adam19,Bcl2a1a,Actb,Glrx,Rnf19b,Casp7,Plscr1,Reps1,Il18rap,Hk2,Ccne1,Ccl5,Rnf14,Snx10,Gem,Casp4,Hopx,Itgal,Tspo,Gng11,Batf,Mdfic,H2-Q7,Itga4,Psmb10,Pttg1,Carhsp1,Fcgr2b,Bcl2a1d,Cox17,Errfi1,Fgl2,Casp1,Bcl2a1b,Cx3cr1,H2-Q4,H2-Q6 |
| 3.645e-07 | -14.82 | Pertussis | KEGG pathways | mmu05133 | 75 | 22 | 7931 | 713 |
C3,Il12b,Il1b,Casp1,Tnf,C1ra,Il6,Itga5,Myd88,Irf1,Il1a,Il10,Nlrp3,Irf8,Fos,Nos2,Casp3,Cd14,Nod1,Jun,Nfkb1,Casp7 |
| 3.645e-07 | -14.82 | Pertussis | KEGG pathways | ko05133 | 75 | 22 | 7931 | 713 |
C1ra,Itga5,Il6,Il1a,Irf1,Myd88,C3,Casp1,Tnf,Il12b,Il1b,Nlrp3,Irf8,Il10,Casp3,Fos,Nos2,Casp7,Cd14,Jun,Nod1,Nfkb1 |
| 3.675e-07 | -14.82 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | 402 | 62 | 15632 | 1249 |
Ezr,Klf3,Rin2,Kremen1,Sgms2,Prnp,Sdc1,Ahr,Klf7,Spred1,Ccne1,Mfap3l,Rhou,Rap1gap2,Egln3,Rictor,Rnf19a,Zfp36,Slc9a1,Acsl1,Rab20,Ell2,Il13ra1,Dyrk2,Dram1,Ppfibp2,Fam20c,Arf4,Tcf4,Mtus1,Swap70,Abcc5,Plekhf2,Ehd1,Hspa2,Mafk,Sat1,Casp3,Ier2,Malt1,Pbx1,Traf5,Golga3,Fzd5,Plk2,Higd1a,Myo1b,Gdf15,Tbc1d13,Sh3bp4,Ttc39b,Arid5b,Spire1,Trib3,St3gal1,Cd55,Ptprj,Trafd1,Inpp1,Lrp11,Bambi,Thbs1 |
| 3.676e-07 | -14.82 | receptor regulator activity | molecular function | GO:0030545 | 523 | 68 | 20217 | 1400 |
Il6,Cxcl10,Insl6,Saa3,Nampt,Ifna4,Pdgfc,Cxcl1,Timp1,Cxcl11,Ifna1,Agrn,Ifna2,Ifna5,Tnf,Il15,Tnfsf8,Sema3c,Il12b,Cxcl14,Csf3,Tnfsf9,Flrt2,Sema4a,Ccl22,Cxcl3,Jag1,Ccl5,Ccl3,Ccl9,Prkce,Bmp2,Csf1,Edn1,Ebi3,Ccl7,Cdc42ep2,Tnfsf14,Ccl8,Osgin2,Tnfsf15,Ccl2,Il18,Vegfc,Ifnb1,Inhba,Il27,Cx3cl1,Cxcl9,Il10,Flrt3,Ccl4,Pf4,Lif,Cxcl2,Gdf15,Tnfsf10,Osm,Il1rn,Il1a,Sema4c,Clcf1,Pdgfb,Ccl12,Kitl,Il1b,Ifna6,Tnfsf4 |
| 3.681e-07 | -14.82 | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN | 168 | 34 | 15632 | 1249 |
Kctd12,Casp2,Ddit4,Trim21,H2-Aa,Ppm1k,Plekha2,Fubp1,4930523C07Rik,Plek,Ccnj,Mthfd1l,Birc3,Pde4b,Ap3m2,Hcls1,Ldlr,Rnf145,Arid5b,Max,Dyrk2,Tmod3,Ldha,Cept1,Sat1,Mdn1,Cd38,Ifit1,Prpf4,Rras2,Phip,Kmo,St3gal6,Rnf139 |
| 3.698e-07 | -14.81 | GSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN | MSigDB lists | GSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN | 199 | 38 | 15632 | 1249 |
Traf1,Isg15,Ifih1,Mapkapk2,Psme1,Evl,H2-Q7,Fas,Ier2,Tap1,Rgs3,Gpc1,Bcl6,H2-Q6,Psmb9,Nfkbia,Ifit2,Parp8,H2-Q4,Glipr2,Rin2,Cish,Peli1,Ifit3b,Cxcl10,Mthfd2,Ptger4,Frmd6,Pkp4,Cd82,Vcam1,Ifit3,Ccl5,Jarid2,Psmb8,Stx6,Il18rap,Reps1 |
| 3.713e-07 | -14.81 | GSE37301_PRO_BCELL_VS_CD4_TCELL_DN | MSigDB lists | GSE37301_PRO_BCELL_VS_CD4_TCELL_DN | 153 | 32 | 15632 | 1249 |
Rtp4,Psmb10,Cx3cl1,Fam133b,Cyth3,Usp18,Evl,Myo10,Cd83,Nod1,Itpr1,Arid5a,Mtus1,Plekhf2,Parp8,Spsb1,Hdac1,Phlpp1,Tnfsf8,Gbp9,Gbp4,Ripk2,Ebi3,Sp110,Ppfibp2,Vcam1,Znrf1,Ccl5,Pde4b,Abtb2,Plscr1,Ube2l6 |
| 3.730e-07 | -14.80 | negative regulation of cell differentiation | biological process | GO:0045596 | 797 | 92 | 20694 | 1406 |
Kremen1,Il4ra,Cav1,Lyn,Cdk5r1,Ahr,Pbx1,Ccnd1,Ptch1,Itgav,Il15ra,Trib3,Hmga2,Il1b,Mdm2,Sirt1,Mmp9,Cflar,Jag1,Kdm4a,Casz1,Sema4a,Bmp2,Rapgef2,Plk2,Lhx2,Cd38,Ifnb1,Jdp2,Zhx2,Sinhcaf,Ankrd17,Cxcl14,Cd74,Bcl6,Ednrb,P2ry12,Sod2,Daxx,Il1a,Tnf,Ubash3b,Katna1,Tmem176a,Pilrb1,Noct,Acvrl1,Trib1,Vasn,Rap1gap2,Foxp4,Gfi1,Notch1,Tomm70a,Il18,Fgl2,Zc3h12a,Lpar1,Hlx,Lrp4,Pdgfb,Tmem178,Cxcl10,Ldlr,Map4k4,Gpr68,Sema3c,Stat3,Nfkbid,Tmem176b,Fas,Ifrd1,Sema4c,Stap1,Ptk2,Dync1i2,Zeb1,Ccl9,Prag1,Clec2d,Myc,Zfp36,Ptpn2,Stat5a,Tspo,Socs1,Hopx,Mecp2,Tnfsf4,Pf4,Nfkbia,Irf1 |
| 3.831e-07 | -14.78 | DNA-binding transcription repressor activity | molecular function | GO:0001217 | 237 | 39 | 20217 | 1400 |
Klf8,Aebp2,Max,Jarid2,Bcl6,Arid5b,Jdp2,Zbtb5,Dach1,Etv3,Eno1,Ifi214,Ets2,Mecp2,Phf6,Mxd1,Zeb1,Myc,Ifi204,Nfil3,Ifi213,Ifi211,Atf3,Ifi205,Hhex,Gfi1,Ikzf1,Foxp4,Irf8,Ifi207,Prdm1,Mndal,Ifi203,Zfp281,Nfkb1,Hinfp,Btg2,Ifi208,Ifi209 |
| 3.831e-07 | -14.78 | DNA-binding transcription repressor activity, RNA polymerase II-specific | molecular function | GO:0001227 | 237 | 39 | 20217 | 1400 |
Ifi205,Hhex,Ifi211,Atf3,Irf8,Gfi1,Ikzf1,Foxp4,Mndal,Ifi203,Prdm1,Ifi207,Hinfp,Btg2,Ifi208,Ifi209,Zfp281,Nfkb1,Klf8,Aebp2,Jarid2,Bcl6,Max,Arid5b,Jdp2,Dach1,Etv3,Ifi214,Eno1,Zbtb5,Myc,Nfil3,Ifi204,Ifi213,Mecp2,Phf6,Ets2,Zeb1,Mxd1 |
| 3.872e-07 | -14.76 | antigen processing and presentation of exogenous antigen | biological process | GO:0019884 | 31 | 12 | 20694 | 1406 |
Fcgr1,H2-Aa,Psme2,H2-Ab1,H2-Eb1,Psme1,Cd74,Ap3b1,Tapbp,Tap2,Fcgr2b,Tap1 |
| 3.872e-07 | -14.76 | regulation of T cell cytokine production | biological process | GO:0002724 | 31 | 12 | 20694 | 1406 |
Nlrp3,Tnfsf4,Il1b,Arid5a,Rsad2,Ifnb1,Il18,Tnfrsf1b,Malt1,Fzd5,Traf2,Il6 |
| 3.872e-07 | -14.76 | positive regulation of interleukin-1 beta secretion | biological process | GO:0050718 | 31 | 12 | 20694 | 1406 |
Tlr2,Hk1,Ccl3,Aim2,Nod2,Ripk2,Ifnar1,Nlrp3,Casp1,Fzd5,Gsdmd,Casp4 |
| 3.876e-07 | -14.76 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_DN | 176 | 35 | 15632 | 1249 |
Tnfsf10,Htr2b,Sp110,Ptk2,Sema4c,Pim2,Cd200,Stat1,Nr4a3,Serpinb9,Inpp5b,St3gal5,Phlpp2,G3bp2,Oas2,Birc3,Pde4b,Gch1,Tnfrsf1b,Tor1aip1,Lcp2,Map2k1,Ptch1,Traf5,Tnfaip3,Gbp2,Ier2,Egr1,Il4ra,Abcb1a,Bnip3,Ppp2r5a,Ifi44,Hivep2,Tnf |
| 3.876e-07 | -14.76 | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN | 176 | 35 | 15632 | 1249 |
Sap30,Srxn1,Piezo1,Rhou,Syne2,Rap1gap2,Ccl5,Tnfrsf1b,Hopx,Itgal,Ccl4,Ralgds,Agpat4,Sema4c,Map3k8,Adrb2,Ctsc,Optn,Chst11,Gpr68,Stk40,Dpy19l1,Pik3r5,Sp140,Cst7,Tmem184b,Rhbdf2,Slamf7,Rgs3,Atp2b4,Fas,Mcoln2,Prnp,Kat2b,Slco3a1 |
| 3.906e-07 | -14.76 | RNA polymerase II proximal promoter sequence-specific DNA binding | molecular function | GO:0000978 | 566 | 72 | 20217 | 1400 |
Junb,Ahr,Klf8,Hivep2,Irf1,Nr3c1,Stat2,Klf7,Stat1,Ets2,Stat3,Kdm6b,Myc,Rfx5,Maff,Ifi204,Nfil3,Ifi213,Jun,Atf3,Ifi211,Cebpd,Foxp4,Hdac1,Notch1,Irf7,Prdm1,Klf6,Mafk,Mndal,Zfp281,Pbx1,Ifi209,Fosb,Jdp2,Aebp2,Max,Nlrc5,Nr4a1,Nr1h3,Mafg,Sp140,Nr4a3,Ifi214,Dach1,Tfec,Mycl,Mxd1,Zeb1,Etv6,Fos,Lhx2,Ifi205,Tcf4,Hhex,Spic,Ikzf1,Nfkb2,Irf8,Batf,Stat5a,Pou2f2,Ifi207,Egr2,Ifi203,Stat4,Batf2,Hif1a,Ifi208,Relb,Irf4,Hinfp |
| 3.998e-07 | -14.73 | regulation of small molecule metabolic process | biological process | GO:0062012 | 328 | 48 | 20694 | 1406 |
Map2k1,Bmp2,Ldlr,Pdk3,Adora2b,Dyrk2,Src,Plek,Stat3,Nr3c1,Nos2,Ptgs2,Ptafr,Hif1a,Ak4,Pdgfb,Il6,Il1b,Ranbp2,Gfi1,Acsl5,Pid1,Trib3,Sirt1,Ier3,Ttc39b,Prkce,Nr4a3,Nfkb1,Slc7a11,Cav1,Ddit4,Pla2g4a,Gk,Tnf,Gfpt1,Ptger4,Atp2b4,Nr1h3,Fabp3,Ptpn2,Htr2a,Myc,Rubcnl,Egr1,Nupr1,Irs2,Kat2b |
| 4.014e-07 | -14.73 | RIPK1-mediated regulated necrosis | REACTOME pathways | R-MMU-5213460 | 14 | 9 | 8608 | 757 |
Birc3,Fas,Cflar,Ripk3,Casp8,Tnfsf10,Birc2,Mlkl,Traf2 |
| 4.014e-07 | -14.73 | Regulated Necrosis | REACTOME pathways | R-MMU-5218859 | 14 | 9 | 8608 | 757 |
Birc2,Tnfsf10,Mlkl,Traf2,Birc3,Cflar,Fas,Ripk3,Casp8 |
| 4.030e-07 | -14.72 | HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | MSigDB lists | HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 184 | 36 | 15632 | 1249 |
Gem,Pdgfrb,Serpine1,Plod2,Eno2,Gja1,Inhba,Htra1,Tgfbi,Lox,Itga5,Plaur,Vegfc,Pmepa1,Vcam1,Notch2,Thbs1,Timp1,Jun,Gadd45b,Plod3,Tagln,Itgav,Vcan,Sat1,Tnc,Mmp14,Il6,Sdc1,Fas,Tnfaip3,Sdc4,Il15,Col4a2,Sgcb,Gpc1 |
| 4.030e-07 | -14.72 | GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_DN | MSigDB lists | GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_DN | 184 | 36 | 15632 | 1249 |
Nfkbib,Slc39a14,Zc3h12c,Irf8,Cacybp,Lmo4,Lap3,Cflar,Il15ra,Rcl1,Gfi1,Wdr43,Trib1,Rcn1,Odc1,Rab20,Mafg,Serpinb9,Egr2,Slc15a3,Il6,Chst11,Dusp4,Srm,Cst7,Spryd7,Rapgef5,Homer1,Cited2,Hmga1,Batf,Lipg,Slc16a1,Pdgfc,Plk3,Atf3 |
| 4.030e-07 | -14.72 | GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_DN | 184 | 36 | 15632 | 1249 |
Hsd17b12,Snx10,Birc3,Rap1gap2,Hat1,Ccrl2,Pdgfb,Cxcl10,Adora2b,Fcho2,Cacnb3,Rcan1,Ell2,Ptk2,Dusp16,Gcnt2,Dek,Gfpt1,Cd40,Itpr1,B4galt4,Apobec3,Trim36,Lipe,Cebpd,Nfkbie,Cdyl2,Pla2g4a,Nlrp3,Tpx2,Rnf135,Malt1,Itga4,Slamf7,Lpcat2,Nod1 |
| 4.030e-07 | -14.72 | GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 184 | 36 | 15632 | 1249 |
Batf,1600014C10Rik,Cd38,Mxd1,Cyth3,Traf1,Gbp3,Sell,Peli1,Stat5a,Klf3,Arhgef3,Tmem184b,Tnip1,Rgs1,Il15ra,Abcc1,Gfi1,Cpeb4,Ptger4,Aida,Rcn1,Ttc39b,Nsmaf,Nr4a3,Lox,Wdr59,Reps1,Nrp2,Plscr1,Stat4,Stx11,Slc4a7,Ccl5,P4ha1,Jdp2 |
| 4.030e-07 | -14.72 | GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_UP | 184 | 36 | 15632 | 1249 |
Ccnj,Cd274,Casp8,Ociad1,Car13,Inhba,Il12rb1,Etv6,Smc5,Pim1,Tmem229b,Rbms1,Fscn1,Clcn7,Tax1bp1,Gcnt2,Prkx,Pmepa1,Morc3,Src,Plekhf2,Traf2,Tiparp,Tmem184b,Zyx,Aebp2,Ccng2,Mxd1,Itga4,Kat2b,F10,Rbms2,Rras2,Cutc,Ripk3,Mvp |
| 4.030e-07 | -14.72 | GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_UP | MSigDB lists | GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_UP | 184 | 36 | 15632 | 1249 |
Rnf114,Bcl6,Cd302,Gbp4,Gbp9,Cp,Gpr84,Slc30a4,Ifih1,Etv3,Extl2,Bfar,Gbp2,Ppfibp1,Ifit1,Aff1,Notch1,Ttc9c,Plek,Zc3h12c,Sco1,Inpp5b,Stx11,Etv6,Rapgef2,Rnf19a,Slc39a14,Parp3,C3,Tlr3,Ppp2r1b,Jak2,Elmod2,Vcam1,Notch2,Dusp16 |
| 4.085e-07 | -14.71 | regulation of nitric-oxide synthase biosynthetic process | biological process | GO:0051769 | 26 | 11 | 20694 | 1406 |
Map2k4,Tlr2,Nod2,Nampt,Ccl2,Stat1,Jak2,Kdr,Edn1,Tlr9,Ptger4 |
| 4.150e-07 | -14.70 | HUMMEL_BURKITTS_LYMPHOMA_DN | MSigDB lists | HUMMEL_BURKITTS_LYMPHOMA_DN | 15 | 9 | 15632 | 1249 |
Cd40,Bcl2a1b,Sqstm1,Nfkbia,Mdfic,Bcl2a1d,Cflar,Stat3,Bcl2a1a |
| 4.181e-07 | -14.69 | BURTON_ADIPOGENESIS_1 | MSigDB lists | BURTON_ADIPOGENESIS_1 | 32 | 13 | 15632 | 1249 |
Errfi1,Maff,Cebpd,Myc,Phlda1,Il6,Dusp2,Ets2,Nfil3,Slc25a25,Dnajb4,Irs2,Ier3 |
| 4.181e-07 | -14.69 | GO_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION | 32 | 13 | 15632 | 1249 |
Syk,H2-Q4,H2-Q6,Ripk2,H2-Q7,Ebi3,Tnfsf4,Cd55,Il12b,Il18,Irf1,Cd80,Tnfrsf14 |
| 4.199e-07 | -14.68 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION | MSigDB lists | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION | 71 | 20 | 15632 | 1249 |
Myd88,Nod1,Ppp2r1b,Irak2,Nfkb2,Tab2,Map2k4,Tlr9,Ripk2,Mapkapk2,Nod2,Dusp4,Nfkbib,Peli1,Fos,Jun,Map2k1,Nfkbia,Dusp6,Ikbkg |
| 4.210e-07 | -14.68 | regulation of T-helper 2 cell differentiation | biological process | GO:0045628 | 13 | 8 | 20694 | 1406 |
Il4ra,Hlx,Nlrp3,Tnfsf4,Bcl6,Il6,Il18,Irf1 |
| 4.232e-07 | -14.68 | CARD | interpro domains | IPR001315 | 25 | 11 | 19984 | 1430 |
Casp1,Casp2,Ripk2,Casp4,Apaf1,Birc2,Birc3,Nod1,Nod2,Nlrc4,Card6 |
| 4.258e-07 | -14.67 | GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | 37 | 14 | 15632 | 1249 |
Tnfsf4,Hlx,Ripk2,Il4ra,Nlrp3,Il12b,Cd83,Cd80,Syk,Cd86,Il6,Pnp2,Il12rb1,Ap3b1 |
| 4.258e-07 | -14.67 | MODULE_263 | MSigDB lists | MODULE_263 | 37 | 14 | 15632 | 1249 |
Ccl12,Ccr1,Ccl2,Cxcl14,Fpr1,Cx3cl1,Cxcl10,Fpr2,Il1a,Ccl4,Plau,Cxcl1,Pf4,Plaur |
| 4.267e-07 | -14.67 | GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 216 | 40 | 15632 | 1249 |
Htra1,Il12rb1,Leng9,Birc3,Ifit1bl2,Fcgr4,Elmod2,Trem1,Cd55,Ripk2,Itpkc,Zc3h12a,Traf3ip2,Trib1,Il12b,Dhx58,Ifit1bl1,Spn,H2-Q4,Eif2ak2,H2-Q6,Birc2,Ankrd17,Nod1,Il15,Il27,Hck,Zc3hav1,Tnfaip3,Nfkbil1,Aim2,Prdm1,H2-Q7,Ddx60,Pml,Stat2,Cd180,Ddx58,Mul1,Trim12c |
| 4.277e-07 | -14.66 | GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | 59 | 18 | 15632 | 1249 |
Ptgs2,Calcrl,Hif1a,Ptafr,Cx3cl1,Nr4a3,Nox1,Stat1,Hmox1,Edn1,Pdgfb,Il6,Jun,Pdgfrb,Tnf,Flt1,Nampt,Ccl5 |
| 4.326e-07 | -14.65 | GO_RESPONSE_TO_DSRNA | MSigDB lists | GO_RESPONSE_TO_DSRNA | 65 | 19 | 15632 | 1249 |
Ddx58,Mul1,Tlr3,Ripk2,Irak3,Ifna2,Zc3hav1,Ifna1,Adar,Cav1,Ifit1bl1,Ifit1bl2,Nfkbia,Eif2ak2,Nfkb1,Ifna5,Ifnb1,Peli1,Ifna6 |
| 4.332e-07 | -14.65 | GO_RIBONUCLEOTIDE_BINDING | MSigDB lists | GO_RIBONUCLEOTIDE_BINDING | 1704 | 191 | 15632 | 1249 |
Srxn1,Tor3a,Mov10,Nos2,Chd9,Gbp2b,Abcc1,Dgkh,Oasl1,Rac3,Pim2,Ddx4,Map2k4,Pcx,Nlrc4,Pim3,Hk3,Atp11b,Me1,Nek6,Papss2,Pikfyve,Tap2,Pdgfrb,Map2k1,Ikbke,Pgk1,Ripk2,Map3k8,Mcm6,Abcc5,Oas3,Ube2f,Apaf1,Irak3,Plk3,Atp11a,Ifih1,Akt3,Ksr1,Ep400,Oas1a,Met,Mcm9,Actb,Pfkl,Dck,Dyrk2,Pik3cd,Irgm2,Prkce,Nod2,Nlrc5,Map3k6,Rab32,Flt1,Pfkfb3,Ciita,Atp2b4,Tap1,Pgs1,Nkiras1,Nlrp3,Oas2,Mthfd1l,Plk2,Ascc3,Acsl5,Slfn9,Abcc4,Oas1g,Dnaja2,Ak4,Spata5l1,Gbp4,Stk40,Mlkl,Ehd1,Hsph1,Src,Hspa1a,Gbp2,Hck,Myo10,Rhoh,Ddx58,Rab19,Rhou,Atm,Hk1,Gem,Sik3,Clcn7,Arf4,Jak2,Rap2c,Vrk2,Ptk2,Trib1,Lyn,Rab20,Slfn8,Katna1,Pde5a,Eif2ak2,Ass1,Syk,Dnaja1,Kif9,Slfn5,Ddx60,Tpx2,Arl4a,Gmppb,Rab10,Arl5b,Rapgef2,Pde4b,Asns,Slfn4,Gtpbp2,Irak2,Atp10a,Trib3,Irgq,Rab21,Gbp9,Tlk2,Dhx58,Hspa2,Sgk3,Gbp3,Rnd1,Trip13,Ube2e2,Pdk3,Gna15,P2ry2,Gbp7,Kdr,Fam20c,Igf1r,Prkar2b,Etnk1,Fignl2,Kif5c,Itpkc,Acvr1b,Acsl1,Abcb1a,Cenpe,Rhof,Rras2,Rnd3,Gclc,Mark2,Rars,Mapkapk2,Wars,Hk2,Uba7,Dgka,Tyk2,Map4k4,Tuba4a,Gch1,Myo1b,Slfn3,Prkx,Cmpk2,Arl5c,Scyl2,Smc5,Pim1,Kif3c,Mdn1,Rhoq,Rab9,Acvr1,Acvrl1,Atp13a1,Dync1h1,Axl,Swap70,Nod1,Ripk3,Clcn5,Rhoc,Ube2e1,Sphk1,Fgr |
| 4.339e-07 | -14.65 | MAPKPHPHTASE | prints domains | PR01764 | 10 | 7 | 5821 | 374 |
Dusp1,Dusp5,Dusp4,Dusp2,Dusp8,Dusp16,Dusp6 |
| 4.439e-07 | -14.63 | type I interferon signaling pathway | biological process | GO:0060337 | 17 | 9 | 20694 | 1406 |
Stat2,Ifnb1,Irf7,Oas2,Ifitm1,Ifnar1,Myd88,Stat1,Ifna1 |
| 4.439e-07 | -14.63 | cellular response to type I interferon | biological process | GO:0071357 | 17 | 9 | 20694 | 1406 |
Myd88,Ifnar1,Ifna1,Stat1,Oas2,Ifitm1,Ifnb1,Stat2,Irf7 |
| 4.439e-07 | -14.63 | positive regulation of interleukin-17 production | biological process | GO:0032740 | 17 | 9 | 20694 | 1406 |
Il18,Myd88,Sphk1,Il6,Il15,Arid5a,Il12b,Osm,Nod2 |
| 4.467e-07 | -14.62 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 177 | 35 | 15632 | 1249 |
Tnfaip3,Cd38,Usp18,Dcp2,Egr1,Marcksl1,Rsad2,Ccng2,Kdm5b,Lztfl1,Dusp2,D1Ertd622e,Abcb1a,Casp3,Spry2,Dnaja1,Birc2,Jun,Pgk1,Htr2b,Ppp2r1b,Rgs1,Nr4a3,Acvr1b,Slc43a3,Ldha,Cd200,Etnk1,G3bp2,Mmd,Ccrl2,Plscr1,Timeless,Ptch1,Rims3 |
| 4.512e-07 | -14.61 | GO_NEGATIVE_REGULATION_OF_CELL_PROLIFERATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_PROLIFERATION | 589 | 82 | 15632 | 1249 |
H2-Eb1,Jarid2,Gja1,Fzd5,Ppp1r15a,Cd274,Osm,Map2k1,Btg2,Wars,Inhba,Sh3bp4,Rapgef2,Ptprj,Hmox1,Ptgs2,Il12b,Thbs1,Vegfc,Il1b,Ptges,Bcl6,Casp3,Stat3,Acvrl1,Prdm1,Parp10,Lif,Nupr1,Pml,Rnf139,Il1a,Intu,Fabp3,Sav1,Tnfrsf8,Bmp2,Cd164,Notch1,Ccl3,Tnfaip3,Atm,Dach1,Cav1,Ifit3,Il10,Ptch1,Fabp7,Zeb1,Eef1e1,Ptgir,Stat1,Pim2,Irf1,Trib1,Lyn,Ifit3b,Jak2,Notch2,Cdkn1a,Morc3,Spn,Eif2ak2,Sod2,Hmga1,Ptpn2,Jun,Spry2,Myc,Il6,Peli1,Pde5a,Ift57,Cdkn2d,Col18a1,Prnp,Kat2b,Etv3,Trp53i11,Il15,Tspo,Tnfrsf14 |
| 4.530e-07 | -14.61 | endoplasmic reticulum | cellular component | GO:0005783 | 1683 | 166 | 20747 | 1409 |
Kcnj2,Dnajb2,Ero1l,Usp25,Tapbp,Osbpl3,Extl2,Plod3,Hp,Gramd1a,Vcam1,Myc,Slc9a1,Rab32,Minpp1,Ptgs2,Hsd17b12,Tor3a,Tgtp2,Tor1aip2,Serp1,Itpr1,Piezo1,Rnf145,Thbs1,Atp11a,Pgs1,Treml4,Cept1,Irgm2,Kdr,Hap1,Rnf139,Anp32a,Sec24a,Atp11b,Mtdh,Slc39a13,Dst,Igtp,Snx10,B3gnt5,Rtn1,Rasgrp1,Rnaset2b,Grina,Traf2,Dhrs9,Ext1,Pla2g4a,Hk2,F10,Lrrc8c,Flrt2,Tapbpl,Tgtp1,Hmox1,Atp10a,P4ha1,Hsd17b7,Ccl2,Acsl5,P2ry13,Tap1,Zc3h12a,Stau1,Pde3b,Ifit2,Rnf19b,Acsl1,Rab19,Caml,Map2k1,Slc37a3,Ahsa1,Gpr85,Rab21,Lnpk,Casp4,Atp13a1,Rsad2,Irgm1,Cav1,Ppp1r15b,1600014C10Rik,Rrs1,Rrbp1,Prkce,Plekhf2,Rnaset2a,Pgap2,Trim13,Tlr9,Shisa3,Plpp3,Rab10,Nck1,Ch25h,Ass1,Pigv,Keap1,Plaat3,Mx1,Bfar,Prnp,Lpcat2,Edn1,Tlr3,Ctsc,Uchl1,Nlrp3,Dnaja1,Bnip3,Syne2,Tmtc2,Ccdc88b,Sgms2,Notch1,Slc7a11,Ksr1,H2-Q6,Ktn1,P4ha2,Tap2,Rtn2,Flrt3,Rab9,Ifi47,Cpeb4,Rcn1,Iigp1,H2-Q4,Tmem67,Dnase1l3,Calcrl,Ppp1r15a,Slamf7,9930111J21Rik1,Nt5c3,Gm4841,Cd74,Gm12185,Ptpn2,Gja1,Sqstm1,Vcpip1,H2-Q7,Itga5,Cst7,Tmem178,Vrk2,Agtrap,F830016B08Rik,Slc30a1,Gm4951,Pnpt1,Pml,Tspo,Gm5431,Fos,Dse,Mppe1,Rhbdf2,Plod2,Cers6,Degs2 |
| 4.534e-07 | -14.61 | NGUYEN_NOTCH1_TARGETS_DN | MSigDB lists | NGUYEN_NOTCH1_TARGETS_DN | 84 | 22 | 15632 | 1249 |
Mthfd2,Ptgs2,Fndc3a,Ell2,Tnfsf4,Daxx,Igf1r,Ppp2r1b,Rbms1,Pcdh7,Tiparp,Ets2,Serp1,Ubr4,Psmb9,Col11a2,Brd2,Ass1,Gadd45b,Dync1h1,Myc,Ext1 |
| 4.536e-07 | -14.61 | GO_ANGIOGENESIS | MSigDB lists | GO_ANGIOGENESIS | 274 | 47 | 15632 | 1249 |
Acvrl1,Acvr1,Sat1,Notch1,Jmjd6,Calcrl,Hif1a,Wars,Nrp2,Pik3r6,Serpine1,Pdgfrb,Fzd5,Vegfc,Prkx,Clic4,Thbs1,Il18,Tgfbi,Ptgs2,Hmox1,Zc3h12a,Mmp14,Edn1,Jun,Itgav,Syk,Ccl12,Nr4a1,Flt1,Angpt1,Pde3b,Col4a2,Cd34,Plau,Cx3cl1,Col18a1,Jag1,Sirt1,Cav1,Kdr,Tnfaip2,Sema4a,Itga5,Egr3,Nox1,Ptk2 |
| 4.537e-07 | -14.61 | DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP | MSigDB lists | DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP | 125 | 28 | 15632 | 1249 |
Rnf19a,Jag1,Slpi,Cacybp,Plekha4,S100a8,Txn1,Il1b,Pmepa1,Pgk1,Cmpk2,Pfkl,Esd,Fam162a,Ldha,Gclm,Cited2,Eno1,Spic,Srm,Plac8,Axl,Samhd1,Cdc42ep2,Cx3cl1,Icam1,Rhoh,Lif |
| 4.627e-07 | -14.59 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN | 185 | 36 | 15632 | 1249 |
Cldnd1,Ppp2r1b,Osbpl3,Jak2,Gfpt1,Stard7,Etnk1,Kpna3,Nsmaf,Psme2,Nfkbib,Stx6,Ccrl2,Ccr1,Hsd17b12,Higd1a,Slc16a1,Ahsa1,Sdc4,Rnf34,Tap1,Lif,Bcor,Tpi1,Traf1,Ccnd2,Pnp2,Cish,Gclm,Minpp1,Rab21,Cox17,Tank,Cyfip1,Arid5a,Itpr1 |
| 4.648e-07 | -14.58 | GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_UP | MSigDB lists | GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_UP | 147 | 31 | 15632 | 1249 |
Ifi44,Gbp4,Gbp9,Dse,Plekha5,Phf11b,Ahr,Phf11c,Sla,Phf11a,Pde3b,Nod1,Gnb4,Crlf3,Rnf135,P2ry14,Atp11a,Rnf139,Slc30a4,Hlx,Magohb,Psme1,Trim14,Bcorl1,Plod2,Fmnl2,Gtpbp2,Phf11d,Rcn1,Rac3,Tlr3 |
| 4.648e-07 | -14.58 | GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP | MSigDB lists | GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP | 147 | 31 | 15632 | 1249 |
St3gal1,Aida,Clcf1,Esd,Snx10,Sesn3,Sipa1l1,Ampd3,Plscr1,Zscan29,Ube2e2,Parp12,Slc30a4,Evl,St3gal3,Il4ra,Cdk5r1,Gbp3,Sla,Zc3hav1,Stat5a,Flt1,Psip1,Abcc5,Plekhf2,Swap70,Slc2a1,Parp14,Fchsd2,Rab11fip1,Dtnb |
| 4.652e-07 | -14.58 | GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 459 | 68 | 15632 | 1249 |
Zc3h12a,Ptger4,Tlr3,Il12b,Il18,Clec5a,Ptgs2,Sec24a,Bambi,Htr2b,Il1b,Hcar2,Vegfc,Gja1,H2-Eb1,Cd274,Fzd5,Mmp13,Csf3,Plk3,Aim2,Fgr,Sphk1,Hif1a,Ddx58,Il1a,Cd14,Plagl2,Cd38,Ifnar1,Casp1,Src,Tnf,Serp1,Micall2,Gpr68,Rbpms,Mdm2,Tlr9,Tnfsf4,Tlr2,Hcls1,Jak2,Nlgn2,Stard7,Rnf31,Clec4n,Casp8,Il10,Tnfsf14,Slc9a1,Rasgrp1,Rhou,Cdk5r1,Il4ra,Irs2,Nlrp3,Clec4e,Cd34,Tnfrsf14,Syk,Ccl12,Bcl2l11,Ezr,Gsdmd,Prkce,Il6,Nod2 |
| 4.655e-07 | -14.58 | GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP | MSigDB lists | GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP | 162 | 33 | 15632 | 1249 |
Psmb9,Oas3,Ifit2,Spsb1,Slc25a37,Casp1,Rsad2,Mmp14,Ccl22,Psmb10,Isg15,Sell,Ahsa1,Cd86,Cnp,Abtb2,Oas1a,Stx11,Tdrd7,Isg20,Trim14,Trim21,Ep400,Htra1,Mmp25,Fam111a,Sema4a,Ifi35,Tlr3,Oasl1,Oas1g,H3f3b,Ppp2r2a |
| 4.671e-07 | -14.58 | RNA polymerase II regulatory region DNA binding | molecular function | GO:0001012 | 831 | 96 | 20217 | 1400 |
Tal2,Ifi209,Zfp281,Plagl1,Mndal,Klf3,Klf6,Notch1,Irf2,Foxp4,Kat2b,Egr1,Atf3,Ifi204,Ifi213,Nfil3,Jun,Rbl1,Ets2,Klf7,Egr3,Nr3c1,Junb,Klf8,Ifi208,Stat4,Batf2,Hif1a,Pcgf5,Ifi207,Pou2f2,Batf,Nfkb2,Nfxl1,Lhx2,Fos,Zeb1,Mxd1,Ifi214,Dach1,Mycl,Nr4a3,Mafg,Arid5b,Jdp2,Bcl6,Aebp2,Jarid2,H3f3b,Fosb,Nfkb1,Pbx1,Irf7,Prdm1,Mafk,Hdac1,Cebpd,Ifi211,Myc,Rfx5,Maff,Stat3,Kdm6b,Eno1,Etv3,Stat1,Zbtb5,Stat2,Ahr,Irf1,Hivep2,Relb,Irf4,Hinfp,Etv5,Ifi203,Rel,Egr2,Irf8,Stat5a,Spic,Ikzf1,Ifi205,Hhex,Tcf4,Prdm9,Etv6,Bcor,Tfec,Sp140,Nr4a1,Nr1h3,Nlrc5,Sirt1,Ier2,Max |
| 4.700e-07 | -14.57 | GO_CIRCULATORY_SYSTEM_DEVELOPMENT | MSigDB lists | GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 734 | 97 | 15632 | 1249 |
Htr2b,Il18,Hmox1,Crkl,Fzd1,Mmp13,Rapgef2,Nrp2,Map2k1,Pdgfrb,Serpine1,Hopx,Flrt2,Fzd5,Gja1,Gys1,Sav1,Tab2,Prdm1,Mecp2,Errfi1,Itgb8,Sat1,Ankrd17,Adam19,Rpgrip1l,Notch2,Itga5,Ptk2,Egr3,Slc9a1,Adap2,Lmo4,Sema3c,Cav1,Atm,Ahr,Cd34,Sgcb,Col4a2,Cx3cl1,Bcor,Col18a1,Ift57,Mmp14,Cited2,Syk,Itgav,Nr4a1,Sec24b,Vegfc,Thbs1,Prkx,Clic4,Lox,Tgfbi,Ptgs2,Zc3h12a,Kdm6b,Ptger4,Wars,Pdgfb,Pik3r6,Junb,Notch1,Bmp2,Jmjd6,Sphk1,Hif1a,Calcrl,Lif,Hhex,Acvrl1,Acvr1,Mdm2,Setdb2,Casp3,Tnfaip2,Kdr,Sema4a,Socs3,Nox1,Sirt1,Jag1,Ptch1,Angpt1,Pde3b,Plau,Egr1,Cox17,Pdpn,Edn1,Tiparp,Jun,Ccl12,Flrt3,Flt1 |
| 4.741e-07 | -14.56 | GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_UP | MSigDB lists | GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_UP | 193 | 37 | 15632 | 1249 |
Clcn5,Klf7,Cd38,Gnb4,Ciita,Sell,Cdkn2d,Pml,Mcoln2,Slc30a4,Itga4,C1ra,Il4i1,Ctsc,Irf4,Fcgr2b,Serp1,Cd40,Tpst1,Mgat1,Bcl6,Tcf4,Ddhd1,Syk,Clic4,Tnfaip2,Lyn,Adrb2,Nr4a3,Dnajb4,Ebi3,Cnn3,Irf8,Zc3h12c,Myadm,Birc3,Jarid2 |
| 4.741e-07 | -14.56 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_UP | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_UP | 193 | 37 | 15632 | 1249 |
Ass1,Plod3,Gsdmd,Mgat1,Cd40,Slc15a3,Pnp2,Igsf6,Cers6,Nfkbie,Ap3b1,Lrp8,Hif1a,Cd80,Adar,Lpcat2,Prdx1,Pilra,Samhd1,Tnfaip3,Hck,Hvcn1,Gda,Ccl5,Ccr1,Casp8,Lcp2,Marco,Htra1,Zc3h7a,Stx11,Pla2g7,Itga5,Mefv,Slamf8,Ptgs2,Tmem123 |
| 4.747e-07 | -14.56 | receptor signaling pathway via STAT | biological process | GO:0097696 | 37 | 13 | 20694 | 1406 |
Il15,Clcf1,Socs1,Stat5a,Stat2,Osm,Il15ra,Socs3,Stat3,Jak2,Stat1,Lif,Stat4 |
| 4.795e-07 | -14.55 | negative regulation of locomotion | biological process | GO:0040013 | 330 | 48 | 20694 | 1406 |
Trib1,Gpr18,Cd200,Spint2,Timp1,Trim13,Notch1,Abr,Lrch1,Jag1,Cnn2,Spred1,Pdgfb,Dusp1,Sema4a,Rap2c,Ptprj,Trim26,Thbs1,Sema3c,Stat3,Serpine1,Fas,Rgcc,Sinhcaf,Rabgef1,Clic4,Sema4c,Trim21,Stap1,Ptk2,Il1rn,Svbp,Ptpn2,Adora2a,Cx3cl1,Cited2,Ptger4,Mecp2,Trim56,D1Ertd622e,Pml,Cx3cr1,Dach1,Ccl12,Evl,Slamf8,Acvrl1 |
| 4.857e-07 | -14.54 | GO_NEGATIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 48 | 16 | 15632 | 1249 |
Tnfaip3,Tnip1,Nlrp3,Tnip3,Stat1,Zc3h12a,Rhoh,G3bp2,Optn,Nfkbid,Sirt1,Nfkbib,Casp8,Psmd10,Il10,Nfkbia |
| 4.873e-07 | -14.53 | MAP kinase tyrosine/serine/threonine phosphatase activity | molecular function | GO:0017017 | 13 | 8 | 20217 | 1400 |
Dusp6,Dusp4,Dusp14,Dusp1,Dusp5,Dusp16,Dusp8,Dusp2 |
| 4.896e-07 | -14.53 | organic substance metabolic process | biological process | GO:0071704 | 6789 | 546 | 20694 | 1406 |
Myc,Pde5a,Plagl2,Dcp1a,Rnf19b,Ppp4r2,Kmo,Ifih1,Pde1b,Birc2,Dusp16,Aff1,Tlr9,Parp8,Pgs1,Ezr,Parp14,Dio2,Scyl2,St3gal1,Dcun1d3,Usp31,Mecp2,Znrf3,Trim12a,Hopx,Ell2,Dnase1l3,Hk3,Mthfd1l,Swap70,Mcm6,Ranbp2,Crkl,Hat1,Usp35,Stat1,Bcor,Il12rb1,Trib1,Mcm10,Ripk3,Adar,Tnks1bp1,Smpdl3b,Src,Hck,Stat3,Parp12,Rbms1,Itpkc,Tpst1,4932438A13Rik,Ampd3,Tapbp,Ak4,Pdgfb,Ero1l,P4ha2,Ptafr,Phyh,Ikbke,Fam111a,Mmp25,Dusp4,Plod3,Ppp1r15a,Mark2,Plod2,Cnot4,Cgas,Il1rn,Kdm6b,Txn1,Fut8,Kmt5a,Ube2e2,Vcam1,Hmgcs1,Ext1,Calcrl,Zhx2,Egr1,Me1,Met,Serp1,Rcl1,Psat1,Myd88,Gch1,Ubash3b,Gfpt1,Phlpp2,Egr2,Kdr,Setdb2,Plaat3,Magohb,Mdfic,Extl2,Mdm2,Mapkapk2,Mppe1,Pttg1,Ppp2r3a,Hmga2,Dtx2,Tmtc2,Hk2,Il4i1,Alas1,Casp3,Cemip2,Itgav,Pcx,Nr4a3,Ccnd1,Prdm9,Slfn8,Grk3,Plk2,Thbs1,Fbxo4,Trem1,Prnp,Ubr4,Ddhd1,Ctsc,Samhd1,Kdm4a,Hif1a,Pgm1,Ccnd2,Sap30,Cflar,Dusp8,Gadd45g,Irak3,Zfp36,Cop1,Morc3,Enpp4,Dhrs9,Itgb8,Tent2,Xrn1,Trim21,Pla2g7,Carmil1,Sgms2,Yju2,B4galt4,Hdac1,Plau,Gbgt1,Adam19,S100a8,Tnfsf4,Hinfp,Acvr1,Ptger4,Mov10,Hdc,Tgs1,Mmp13,Egln3,Irak2,Tiparp,Vcpip1,Znrf1,Lipe,Gsta3,Plpp1,Hmox1,Tlr2,Pim1,Map4k4,Trmt1l,Icosl,Dyrk2,Gcnt2,Asns,Cmpk2,Aoah,Ass1,Nmi,Tlk2,Ptprj,Htra1,Mcmbp,Irgm2,Parp9,Endod1,Nos2,Smc5,Oas2,Psmb6,Rnf31,Junb,Malt1,Prpf4,Cd74,C3,Dusp28,Psip1,Larp1,Igf1r,Map3k6,Vrk2,Fgr,Wars,Cdkn2d,Srm,Nod1,Ccl5,Bfar,Col4a2,Noct,Pml,Pim2,Zc3h12c,Eya4,Ccnj,Ago3,Syk,Smox,Stat4,Agpat4,Sod2,Trim36,Fam20c,Arf4,Axl,Acsl5,Trim13,Txnrd1,Hhex,Helz2,Usp18,Htr2b,Ptch1,Lmo4,Slc7a11,Tnip1,Lyn,Chst11,Ahr,Parp11,C1rl,Sat1,Degs2,Timeless,Cdyl,Isg20,Dusp2,Upp1,Tent4a,Atm,Acsl1,Rnaset2b,Fos,Olr1,Ankib1,Ptpn2,Pdgfrb,Ptk2,Gda,Nr1h3,Fosb,Ch25h,Kdm5b,Prkx,Gbe1,Prag1,Dusp14,Dgkh,Rhoq,Zc3h7a,Dnajb2,Snapc1,Ccng2,Il15,Gsr,Nupr1,Psmb9,Arrdc4,Dcp2,Gtpbp2,Med21,Cept1,Batf,Birc3,Psmb8,Eef1e1,Herc6,Inpp1,Socs3,Arid4a,Slfn9,Rnf34,Apobec3,Stat5a,Ascc3,Map3k8,Ppm1k,Eif2ak2,Pnpt1,Socs1,Pdpn,Rnf139,Spsb1,Akt3,Pdss1,Tcea1,Sphk1,Jak2,Ptges,Rictor,Irf7,Tnfaip3,Inhba,Pgk1,Tyk2,Nr3c1,Nxf1,Phlda1,Peli1,Odc1,Map2k1,Trim12c,Eif4g2,Pdk3,Lif,Arg2,Usp12,Flt1,Oas1a,Tnfsf15,Ube2e1,Gpc1,Dpy19l1,Wdr43,Psma6,Bnip3,Psmb10,Tra2a,Tha1,Agrn,Tmem67,Srgn,Mthfd2,Rnf19a,Nck1,Acvrl1,Casp8,Pikfyve,Denr,Nampt,Rbbp8,Trim56,Eno2,Uba7,Gys1,Pla2g4a,Sik3,Dusp6,Rffl,Inpp5b,Ttc39b,Mlkl,Hsd17b12,St3gal5,Btg2,Polr2g,Tet2,Trib3,Isg15,Pim3,Sla,Il1b,Acp2,Tlr3,Plat,Ifnar1,Ppp2r5a,Ppm1l,Prkce,Cdk5r1,Keap1,Ube2l6,Cpeb4,Dck,Plek,Casp2,Bmp2,Dusp1,Pgap2,Acvr1b,Mcm9,Otud1,Lox,Phgdh,Saa3,Gclm,Dtx3l,Svbp,Ep400,Irf4,Lnpep,Usb1,Mmp14,Sgk3,Cers6,Mtmr14,C1ra,Med13,Casp7,Ccr3,Trip13,Prkar2b,Socs7,Cish,Edn1,Hmga1,Papss2,Ube2f,Rubcnl,Fas,Nsd3,Esd,Rars,Phlpp1,Gk,Pigv,Klhl25,Cnp,Asf1a,Il10,Map2k4,Ppp1r15b,Plpp3,Usp42,Hspa1a,Tspo,Naa25,Mdn1,Il18,Fgl2,Zc3h12a,Mocs1,Chmp4b,Crbn,Top3a,Sbds,Usp53,Tut7,Casp4,B3gnt5,Hivep2,Hsd17b7,Jarid2,Casp1,Ccne1,Dgka,Idi1,Rnaset2a,Rrs1,Ldlr,Smg7,Nek6,Usp25,Mthfr,Traf2,Stk40,Ripk2,Mul1,Pfkfb3,Mvp,Gpd2,Rnf14,Lipg,P4ha1,Parp3,Gclc,Lpcat2,Adgb,Nt5c3,Pfkl,Nlgn2,Dr1,Kat2b,Jmjd6,Slc16a1,Uchl1,Hk1,Dse,Etnk1,Prpf38a,Angpt1,Atf3,Taf4b,Cpd,Parp10,Asah2,St3gal6,Acpp,Armc8,Ccl12,Caml,Rnf135,Pcgf5,Tcf4,Jun,Plk3,Tnf,Mapkbp1,Lap3,Arel1,Plcl2,Ctu1,Sirt1,Mmp9,Acod1,Osm,St3gal3,Cav1,Pbx1,Adhfe1,Trim30a,Pik3cd,Ldha,Plscr1,Sde2,Dusp5,Tpi1,F10,Ppp2r2a,Marf1,Mrpl52,Nfil3,Ddx4,Ksr1,Oasl2,Mmd,Mgat1,Ptgs2 |
| 4.901e-07 | -14.53 | GO_AGING | MSigDB lists | GO_AGING | 258 | 45 | 15632 | 1249 |
Smc5,Nfkb2,Vcam1,Il1b,Ccl5,Map2k1,Serpine1,Cd86,Cnp,Ppp1r15a,Pml,Icam1,Apaf1,Serp1,Timp1,Cp,Stat3,Socs3,Adrb2,Cdkn1a,Ednrb,Tnfrsf1b,Atm,P2ry2,Il10,Cav1,Casp2,Sirt1,Fas,Cx3cl1,Htr2a,Tspo,Il15,Ccl12,Sod2,Ass1,Morc3,Jun,Hmga1,Fos,Il6,Edn1,Pla2g4a,Ctsc,Nqo1 |
| 4.939e-07 | -14.52 | GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE | 140 | 30 | 15632 | 1249 |
Ptprj,Uchl1,Dusp5,Aida,Lyn,Tnip1,Dusp16,Igf1r,Il1b,Dusp6,Cav1,Atf3,Lif,Spred1,Rgs3,Dusp14,Irak3,Dusp1,Ezr,Hsph1,Rgs14,Psmd10,Ptpn2,Dnaja1,Spry2,Dusp8,Dusp2,Myc,Errfi1,Dusp4 |
| 5.000e-07 | -14.51 | GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_1 | MSigDB lists | GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_1 | 78 | 21 | 15632 | 1249 |
Ccl4,Irak2,Ccl3,Irak3,Zc3h12a,Egr1,Ptger4,Fas,Cx3cl1,Hif1a,Icam1,Ccl22,Ccl2,Il6,Edn1,Ccl12,Ccl5,Nfkb1,P2ry2,Klf2,Psmb9 |
| 5.024e-07 | -14.50 | CASPASE_P20 | prosite domains | PS50208 | 12 | 8 | 13278 | 1037 |
Casp4,Casp1,Malt1,Casp7,Cflar,Casp8,Casp2,Casp3 |
| 5.051e-07 | -14.50 | GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_UP | MSigDB lists | GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_UP | 155 | 32 | 15632 | 1249 |
Ampd3,Phlda1,Trim14,Slc25a12,Zscan29,Stat4,Casp8,Ppp1r15a,Ralgds,Abcc4,Epsti1,Dusp5,Dgkh,Ptprj,Map2k4,Odc1,Dhx58,Phlpp1,Adhfe1,Rab32,Axl,Tpst1,Znfx1,Itpr1,Cd80,Fbrsl1,Tnfaip3,Zc3hav1,Cd38,Pml,P2ry14,Cyth3 |
| 5.063e-07 | -14.50 | LU_AGING_BRAIN_UP | MSigDB lists | LU_AGING_BRAIN_UP | 250 | 44 | 15632 | 1249 |
Ifi213,Nfkbia,Itgav,Lrp4,Ifi209,Cd302,Tiparp,Ifi205,Sdc2,Rin2,Phlpp1,Vcan,Hspa2,Cebpd,Nupr1,Palld,Hif1a,Ifi214,Gng11,Slc16a1,Ifi207,Aff1,Myo10,Mfap3l,Csrp1,Gja1,Cav1,Tor1aip1,Mndal,Plod2,Irf7,Ifi211,Ddit4,Ifi208,Htra1,Ifi203,Hp,Smc5,Ifi204,Clic4,Tmem123,Bambi,Gng12,Zhx2 |
| 5.108e-07 | -14.49 | LEI_MYB_TARGETS | MSigDB lists | LEI_MYB_TARGETS | 292 | 49 | 15632 | 1249 |
Me1,Gng11,Ccnd2,Pttg1,Nxf1,Tpx2,Rars,Palld,Myc,Il6,Psmd10,Dnaja1,Ccl12,Pfkl,Cdkn1a,Cflar,Idi1,Tnip1,Rac3,Isg20,Alas1,Cav1,Lcn2,S100a8,Crim1,Daxx,Isg15,Nupr1,Ccnd1,Sat1,Pnp2,Axl,Txnrd1,Slc16a3,Stip1,Il1b,Il1rn,Serpinb2,Clic4,Tgfbi,Arid5b,Hmox1,Slc7a5,Plk2,Asns,Serpine1,Brd2,Gja1,Tuba4a |
| 5.150e-07 | -14.48 | Rela (v-rel reticuloendotheliosis viral oncogene homolog A (avian)) | protein interactions | 19697 | 41 | 16 | 7778 | 753 |
Il6,Hdac1,Ifnb1,Jun,Il12b,Nfkb1,Cxcl2,Cxcl10,Nos2,Sirt1,Nfkb2,Nfkbia,Sele,Cited2,Bcl2a1a,Nfkbib |
| 5.161e-07 | -14.48 | positive regulation of cell killing | biological process | GO:0031343 | 98 | 22 | 20694 | 1406 |
H2-Q7,Tap2,H2-Q4,H2-T22,Stap1,H2-T10,Il12b,Nectin2,H2-T24,Nos2,Cxcl1,Stat5a,Klrk1,Raet1e,Rasgrp1,Il18rap,Pvr,H60b,H2-Q6,H2-M2,Bcl2l11,Ccl2 |
| 5.247e-07 | -14.46 | nitrogen compound metabolic process | biological process | GO:0006807 | 5824 | 477 | 20694 | 1406 |
Ptch1,Lmo4,Htr2b,Usp18,Helz2,Parp11,C1rl,Ahr,Chst11,Lyn,Slc7a11,Tnip1,Arf4,Fam20c,Txnrd1,Trim13,Acsl5,Axl,Acsl1,Atm,Tent4a,Upp1,Ankib1,Fos,Olr1,Rnaset2b,Cdyl,Timeless,Degs2,Sat1,Dusp2,Isg20,Wars,Vrk2,Fgr,Map3k6,Larp1,Igf1r,Psip1,Ccl5,Cdkn2d,Srm,Nod1,Prpf4,Malt1,Junb,Rnf31,Psmb6,Oas2,Dusp28,Stat4,Smox,Syk,Sod2,Trim36,Col4a2,Noct,Bfar,Ago3,Eya4,Ccnj,Pim2,Zc3h12c,Pml,Gsta3,Lipe,Znrf1,Vcpip1,Pim1,Hmox1,Tlr2,Plpp1,Irak2,Tiparp,Htra1,Smc5,Nos2,Endod1,Parp9,Irgm2,Asns,Gcnt2,Icosl,Dyrk2,Trmt1l,Map4k4,Ptprj,Tlk2,Nmi,Ass1,Cmpk2,Trim21,Xrn1,Tent2,Sgms2,Carmil1,Pla2g7,Zfp36,Irak3,Gadd45g,Itgb8,Enpp4,Morc3,Cop1,Mmp13,Hdc,Tgs1,Mov10,Ptger4,Egln3,Adam19,Plau,Hdac1,Yju2,Hinfp,Acvr1,S100a8,Cemip2,Itgav,Casp3,Alas1,Il4i1,Hk2,Ccnd1,Mdm2,Slc7a2,Extl2,Tmtc2,Dtx2,Hmga2,Ppp2r3a,Pttg1,Mppe1,Mapkapk2,Ccnd2,Hif1a,Kdm4a,Dusp8,Sap30,Cflar,Prnp,Trem1,Fbxo4,Thbs1,Plk2,Slfn8,Grk3,Prdm9,Samhd1,Ctsc,Ubr4,Ext1,Hmgcs1,Vcam1,Ube2e2,Kmt5a,Fut8,Egr1,Zhx2,Ppp1r15a,Plod3,Dusp4,Mmp25,Cgas,Kdm6b,Cnot4,Plod2,Mark2,Plaat3,Egr2,Kdr,Setdb2,Phlpp2,Gfpt1,Ubash3b,Mdfic,Magohb,Myd88,Psat1,Rcl1,Serp1,Met,Gch1,Stat1,Usp35,Bcor,Prdx5,Hat1,Adar,Mcm10,Ripk3,Trib1,Il12rb1,Swap70,Hk3,Mthfd1l,Dnase1l3,Ranbp2,Mcm6,P4ha2,Ero1l,Pdgfb,Ak4,Ikbke,Hck,Parp12,Stat3,Src,Smpdl3b,Tnks1bp1,Tapbp,Ampd3,Tpst1,Dusp16,Birc2,Pde1b,Ifih1,Aff1,Dcp1a,Myc,Pde5a,Kmo,Ppp4r2,Rnf19b,Znrf3,Mecp2,Usp31,Dcun1d3,Hopx,Ell2,Trim12a,Parp8,Tlr9,St3gal1,Scyl2,Dio2,Parp14,Trim30a,Adhfe1,St3gal3,Osm,Sirt1,Mmp9,Arel1,Ctu1,Ddx4,Nfil3,Mgat1,Mmd,Ksr1,Oasl2,Dusp5,Sde2,Plscr1,Marf1,Mrpl52,Ppp2r2a,F10,Tpi1,Dr1,Nlgn2,Pfkl,Hk1,Uchl1,Jmjd6,Kat2b,P4ha1,Arid5b,Adgb,Nt5c3,Lpcat2,Gclc,Parp3,Rnf135,Lap3,Tnf,Mapkbp1,Plk3,Pcgf5,Tcf4,Jun,Angpt1,Prpf38a,Dse,Ccl12,Asah2,St3gal6,Armc8,Acpp,Parp10,Cpd,Taf4b,Crbn,Usp53,Sbds,Top3a,Zc3h12a,Il18,Fgl2,Mdn1,Chmp4b,Mocs1,Traf2,Mthfr,Usp25,Nek6,Rnf14,Mvp,Mul1,Ripk2,Stk40,Hivep2,B3gnt5,Casp4,Tut7,Ldlr,Smg7,Rnaset2a,Rrs1,Ccne1,Casp1,Jarid2,Socs7,Trip13,Nsd3,Ube2f,Papss2,Hmga1,Usb1,Irf4,Lnpep,Ep400,Svbp,Gclm,Dtx3l,Casp7,Ccr3,Med13,Mtmr14,C1ra,Cers6,Sgk3,Mmp14,Hspa1a,Usp42,Naa25,Klhl25,Pigv,Phlpp1,Rars,Ppp1r15b,Map2k4,Asf1a,Cnp,Ifnar1,Plat,Tlr3,Keap1,Prkce,Cdk5r1,Ppp2r5a,Ppm1l,Btg2,St3gal5,Mlkl,Acp2,Il1b,Sla,Isg15,Pim3,Trib3,Tet2,Polr2g,Acvr1b,Pgap2,Dusp1,Saa3,Phgdh,Lox,Otud1,Mcm9,Dck,Cpeb4,Ube2l6,Bmp2,Casp2,Tmem67,Srgn,Tha1,Psmb10,Tra2a,Bnip3,Dusp6,Sik3,Rffl,Acvrl1,Nck1,Mthfd2,Rnf19a,Uba7,Eno2,Rbbp8,Trim56,Denr,Nampt,Casp8,Tlr6,Jak2,Sphk1,Tcea1,Tyk2,Pgk1,Inhba,Tnfaip3,Irf7,Ptges,Rictor,Spsb1,Rnf139,Akt3,Oas1a,Flt1,Usp12,Arg2,Lif,Psma6,Wdr43,Gpc1,Dpy19l1,Ube2e1,Tnfsf15,Peli1,Phlda1,Nr3c1,Pdk3,Eif4g2,Trim12c,Map2k1,Odc1,Rhoq,Dusp14,Nupr1,Gsr,Il15,Ccng2,Dnajb2,Snapc1,Zc3h7a,Pdgfrb,Ptpn2,Prag1,Fosb,Kdm5b,Prkx,Ptk2,Gda,Rnf34,Apobec3,Slfn9,Arid4a,Herc6,Eef1e1,Pnpt1,Eif2ak2,Ppm1k,Map3k8,Ascc3,Stat5a,Batf,Cept1,Med21,Gtpbp2,Arrdc4,Dcp2,Psmb9,Psmb8,Birc3 |
| 5.254e-07 | -14.46 | positive regulation of interferon-gamma production | biological process | GO:0032729 | 76 | 19 | 20694 | 1406 |
Tnfsf9,Fzd5,Il18,Cd14,Pde4b,Tlr9,Il27,Rasgrp1,Arid5a,Il12b,Il1b,Tnfsf4,Irf8,Ifnar1,Tlr3,Klrk1,Tnf,Ripk2,Il12rb1 |
| 5.305e-07 | -14.45 | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_UP | MSigDB lists | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_UP | 186 | 36 | 15632 | 1249 |
Apobec3,Cd302,Csf3r,Dusp8,Cish,Pde1b,Irf2,Nck1,Arg2,Gbp3,Fabp3,Kat2b,Myo10,Aff1,Hk1,Heatr6,Med21,P2ry2,Samsn1,Plscr1,Fabp7,Zeb1,Spint2,Hk2,Hivep3,Ube2e2,Sh3bp4,Traf3ip2,Ptger4,Rnf19b,Grina,Ptgs2,Irf1,Tax1bp1,Ptges,Cdkn1a |
| 5.305e-07 | -14.45 | GSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_DN | MSigDB lists | GSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_DN | 186 | 36 | 15632 | 1249 |
Atp6v1d,Pde4b,Trim56,Ube2e2,Rasgrp1,Ext1,Zeb1,Cnn3,Med13,Acvr1b,Gpd2,Cdc42ep4,Ptk2,Egr3,Kdm6b,Cd200,Ptgir,Plaur,Pmepa1,Gpr18,Spsb1,Acvrl1,Ikzf1,Egr2,Ubtd2,Zfp281,Cyth3,Calcrl,Rhoh,Aff1,Spred1,Rab3ip,Myo10,Slfn5,Gnb4,Zbp1 |
| 5.316e-07 | -14.45 | GO_REGULATION_OF_B_CELL_ACTIVATION | MSigDB lists | GO_REGULATION_OF_B_CELL_ACTIVATION | 98 | 24 | 15632 | 1249 |
Cd38,Tnfaip3,Ahr,Fas,Prdm1,Cd74,Irs2,Casp3,Mmp14,Peli1,Il6,Nod2,Syk,Bcl6,Cd40,Clcf1,Cdkn1a,Tnfsf4,Lyn,Bst1,Inhba,Atm,Il10,Samsn1 |
| 5.382e-07 | -14.43 | GO_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 72 | 20 | 15632 | 1249 |
Aida,Lyn,Ptprj,Dusp5,Uchl1,Rgs3,Spred1,Dusp16,Irak3,Il1b,Dusp14,Cav1,Rgs14,Dnaja1,Dusp1,Dusp6,Dusp4,Spry2,Dusp8,Dusp2 |
| 5.395e-07 | -14.43 | GGGNNTTTCC_NFKB_Q6_01 | MSigDB lists | GGGNNTTTCC_NFKB_Q6_01 | 126 | 28 | 15632 | 1249 |
Slamf8,Cpeb4,Ptges,Tfec,Nfkb2,Rap2c,Tnip1,Il1rn,Rbms1,Gem,Cd86,Rel,Ccl5,Tnfrsf1b,Myadm,Birc3,Tnfsf15,Cd74,Ccnd2,Relb,Tnks1bp1,Batf,N4bp1,Ehd1,Nfkbia,S1pr2,Slc44a1,Il6 |
| 5.397e-07 | -14.43 | GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN | 163 | 33 | 15632 | 1249 |
Ppfibp1,Cd38,Hvcn1,Sav1,Gbp3,Il4ra,Calcrl,Irf2,Ccng2,Cpd,I830077J02Rik,Treml2,Ogfrl1,Stap1,Top3a,Abcb1a,Irf4,Tbc1d1,Bcl6,Cd40,Tspan3,Plekhf2,Flt1,Sema4a,Serpinb9,St3gal1,Ube2e2,Mmd,Plekha2,Sipa1l1,Myo1b,Nfkb1,Jarid2 |
| 5.417e-07 | -14.43 | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_DN | MSigDB lists | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_DN | 194 | 37 | 15632 | 1249 |
Slc39a14,Rhou,Maff,Dusp6,Ltbp2,Lcn2,Cxcl1,Thbs1,Ldlr,Pkp4,Gsta3,Cdkn1a,Pmepa1,Nfil3,Hp,Ppa1,Socs3,Lpar1,Adora2b,Lox,Edn1,Carhsp1,Mmp14,Myc,Ifrd1,Gadd45g,Spsb1,Lipe,Plekhf2,Timp1,Myd88,Rras2,Bmp2,Stau1,Angpt1,Ccl22,Arg2 |
| 5.417e-07 | -14.43 | CHANG_IMMORTALIZED_BY_HPV31_DN | MSigDB lists | CHANG_IMMORTALIZED_BY_HPV31_DN | 54 | 17 | 15632 | 1249 |
Lcn2,Fos,Tagln,Ifit2,Ifit1bl1,Ifit1bl2,Oas2,Slpi,Ifi44,Trib1,Ptgs2,Stat1,Mxd1,Ifi35,Hmgcs1,Serpinb2,Il1rn |
| 5.480e-07 | -14.42 | GO_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | MSigDB lists | GO_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 202 | 38 | 15632 | 1249 |
Tlr3,Tlr9,Zc3h12a,Dyrk2,Ptgs2,Il18,Il12b,Tlr2,Jak2,Hcls1,Bambi,Cdkn1a,Keap1,Il1b,Txn1,Tnfsf14,Il10,Slc9a1,Nfkbib,G3bp2,Csf3,Sirt1,Fzd1,Parp10,Nfkbil1,Ddx58,Sphk1,Nlrp3,Prdx1,Angpt1,Mdfic,Tnf,Nfkbia,Psmd10,Il6,Mdm2,Nfkbie,Rbpms |
| 5.563e-07 | -14.40 | RNA polymerase II regulatory region sequence-specific DNA binding | molecular function | GO:0000977 | 823 | 95 | 20217 | 1400 |
Max,Ier2,Sirt1,Nlrc5,Nr4a1,Nr1h3,Sp140,Bcor,Tfec,Etv6,Prdm9,Hhex,Tcf4,Ifi205,Spic,Ikzf1,Irf8,Stat5a,Egr2,Rel,Ifi203,Etv5,Irf4,Relb,Hinfp,Ahr,Irf1,Hivep2,Stat2,Zbtb5,Eno1,Stat1,Etv3,Stat3,Kdm6b,Maff,Rfx5,Myc,Ifi211,Cebpd,Hdac1,Prdm1,Irf7,Mafk,Nfkb1,Pbx1,Fosb,Jdp2,Arid5b,H3f3b,Aebp2,Jarid2,Bcl6,Mafg,Nr4a3,Ifi214,Mycl,Dach1,Zeb1,Mxd1,Fos,Lhx2,Nfxl1,Nfkb2,Batf,Pou2f2,Ifi207,Pcgf5,Stat4,Hif1a,Batf2,Ifi208,Junb,Klf8,Nr3c1,Egr3,Klf7,Ets2,Ifi213,Nfil3,Ifi204,Jun,Atf3,Egr1,Kat2b,Foxp4,Irf2,Notch1,Klf3,Klf6,Mndal,Plagl1,Zfp281,Ifi209,Tal2 |
| 5.569e-07 | -14.40 | GO_POSITIVE_REGULATION_OF_CHEMOTAXIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CHEMOTAXIS | 112 | 26 | 15632 | 1249 |
Ccr1,Ccl5,Tnfsf14,Serpine1,Pdgfrb,Pdgfb,Csf1,Pla2g7,Met,Cxcl2,Lpar1,Cxcl10,Cmklr1,Cxcl1,Kdr,Ccl4,Thbs1,Vegfc,Pf4,Il1b,Ccl12,Swap70,Il6,Cxcl14,Cd74,Cx3cl1 |
| 5.657e-07 | -14.39 | BYSTROEM_CORRELATED_WITH_IL5_DN | MSigDB lists | BYSTROEM_CORRELATED_WITH_IL5_DN | 60 | 18 | 15632 | 1249 |
Mapkapk2,Kpna3,Mxd1,Ptprj,Casp7,Pik3cd,Cd180,Pim1,Adar,Sla,Syk,Eif2ak2,Hivep2,Itgal,Nr3c1,Pstpip2,Ikzf1,Rab10 |
| 5.683e-07 | -14.38 | GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_DN | 171 | 34 | 15632 | 1249 |
Irak2,Tnip1,Cldnd1,Tnfsf10,Osbpl3,Nfil3,Cd200,Endod1,Ptger4,Map3k8,Nr4a3,Rcn1,Kcna3,Reps1,Csf1,Snx2,Nfkb1,Tnfrsf1b,P4ha1,Cd86,Samsn1,Etv5,Ppm1l,Cyth3,Ubash3b,Plagl1,Itgb8,Pnp2,Dusp4,Ppp1r14b,Nr4a1,Tank,Swap70,Homer1 |
| 5.683e-07 | -14.38 | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN | MSigDB lists | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN | 171 | 34 | 15632 | 1249 |
Mdn1,1110038F14Rik,Dock10,Kdm5b,Phf11b,Phf11a,Cutc,Myd88,Cd83,Phf11c,Pikfyve,Sell,Nmi,Trim14,Caml,Inpp5b,Cd69,Rnaset2a,Chd9,Ust,Zcchc2,Notch2,Rbms1,Zhx2,Sp110,Snn,Rcl1,Rnaset2b,Dck,Ripk2,H2-Ab1,Lyn,Pik3cd,Phf11d |
| 5.723e-07 | -14.37 | positive regulation of endothelial cell proliferation | biological process | GO:0001938 | 91 | 21 | 20694 | 1406 |
Vegfc,Pdgfb,Htr2b,Kdr,Stat5a,Rictor,Cav1,Jun,Hmox1,Itga4,Stat3,Ccl2,Sirt1,Egr3,Acvrl1,Il10,Akt3,Adora2b,Ccr3,Nr4a1,Bmp2 |
| 5.782e-07 | -14.36 | Proteoglycans in cancer | KEGG pathways | ko05205 | 204 | 41 | 7931 | 713 |
Slc9a1,Thbs1,Fzd1,Itgav,Gpc1,Src,Tlr2,Ptk2,Akt3,Ptch1,Hcls1,Sdc2,Pik3cd,Flnb,Tnf,Kdr,Mmp9,Stat3,Cav1,Itga5,Actb,Fas,Rras2,Ezr,Mdm2,Plau,Casp3,Igf1r,Sdc4,Sdc1,Met,Map2k1,Myc,Fzd5,Cdkn1a,Hif1a,Ppp1r12b,Il12b,Itpr1,Plaur,Ccnd1 |
| 5.782e-07 | -14.36 | Proteoglycans in cancer | KEGG pathways | mmu05205 | 204 | 41 | 7931 | 713 |
Map2k1,Myc,Fzd5,Sdc1,Met,Ppp1r12b,Hif1a,Cdkn1a,Il12b,Itpr1,Ccnd1,Plaur,Ezr,Rras2,Mdm2,Plau,Igf1r,Sdc4,Casp3,Sdc2,Pik3cd,Flnb,Kdr,Tnf,Actb,Fas,Itga5,Cav1,Stat3,Mmp9,Slc9a1,Thbs1,Fzd1,Src,Tlr2,Akt3,Ptk2,Itgav,Gpc1,Hcls1,Ptch1 |
| 5.803e-07 | -14.36 | GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_DN | MSigDB lists | GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_DN | 141 | 30 | 15632 | 1249 |
H2-Ab1,Arl5c,Stat1,Trafd1,Osbpl3,Psmb8,Inhba,Wars,Il12rb1,Tmem26,Trim56,Ube2l6,Psme2,Cd74,Pttg1,H2-Q7,Gbp2,Rhoc,1600014C10Rik,Slc16a1,H2-Q6,Znfx1,Eno1,Dync1h1,Nlrc5,Tnf,H2-Q4,Gsdmd,Lrp4,Il18bp |
| 5.803e-07 | -14.36 | GO_RESPONSE_TO_IONIZING_RADIATION | MSigDB lists | GO_RESPONSE_TO_IONIZING_RADIATION | 141 | 30 | 15632 | 1249 |
Ccnd1,Mecp2,Tlk2,Myc,Casp3,Ifi205,Ifi209,Ccl12,Ifi213,Ifi207,Ifi214,Hif1a,Icam1,Trim13,Egr1,Pml,Ifi203,Sirt1,Ifi208,Ifi211,Mndal,Cav1,Dcun1d3,Atm,Cdkn1a,Il1b,Vcam1,Cxcl10,Ifi204,Socs3 |
| 5.813e-07 | -14.36 | monocyte chemotaxis | biological process | GO:0002548 | 32 | 12 | 20694 | 1406 |
Ccl5,Cx3cl1,Ccl3,Ccl7,Flt1,Ccl4,Pdgfb,Ccl12,Ccl9,Ccl2,Ccl8,Ccl22 |
| 5.846e-07 | -14.35 | DORN_ADENOVIRUS_INFECTION_12HR_UP | MSigDB lists | DORN_ADENOVIRUS_INFECTION_12HR_UP | 28 | 12 | 15632 | 1249 |
Ell2,Egr3,Ddx58,Nfkb2,Rnd3,Ifit1bl2,Ifit1bl1,Ifit2,Junb,Nr4a1,Fubp1,Plk2 |
| 5.909e-07 | -14.34 | GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_DN | 179 | 35 | 15632 | 1249 |
Prdx1,Batf,Gclc,Upp1,Gbe1,Lif,Nqo1,Gsr,Mdn1,Stard5,Peli1,Slc39a4,Dusp2,Ttc39c,Hivep2,N4bp1,Sqstm1,Hcar2,Hcls1,Grina,Ier3,Slc31a1,Pla2g7,Eya4,Maff,Hk2,Reps1,Fabp7,Flnb,Col11a2,Samsn1,Cacybp,Igsf9,Pde4b,Nampt |
| 5.956e-07 | -14.33 | Regulation of IFNA signaling | REACTOME pathways | R-MMU-912694 | 26 | 12 | 8608 | 757 |
Ifna5,Tyk2,Usp18,Socs1,Ifna2,Ifna6,Ifna1,Ifna4,Stat1,Ifnb1,Stat2,Ifnar1 |
| 5.973e-07 | -14.33 | WEST_ADRENOCORTICAL_TUMOR_DN | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_DN | 499 | 72 | 15632 | 1249 |
Olfml3,Mvp,Plk3,Ier2,Nupr1,Icam1,Socs1,St3gal6,Micall2,Fut8,Mecp2,Rbpms,Cebpd,C1ra,Dusp1,Klf6,Axl,Arhgef3,Cd302,Tnfsf10,Plat,Htr2b,Atp10a,Ptger4,Cd55,Parp3,Nr4a3,Cdc42ep4,Ext1,Btg2,Phlda1,Dgka,Fzd1,Maff,Junb,Csrp1,Klf2,Hopx,Cnp,Fosb,Cd34,Tspo,Fas,Egr1,Pla2g4a,Abcb1a,Irf4,Vcan,Nr4a1,Gsdmd,Cnn2,Tagln,Ccl12,Fos,Zyx,H3f3b,Egr3,Ifi35,Kif5c,C3,Irf1,Lpar1,Asb13,Ier3,Csf1,Zfp36,Alas1,Ampd3,Sirt1,Pid1,Ptch1,Gem |
| 6.012e-07 | -14.32 | AMIT_EGF_RESPONSE_20_HELA | MSigDB lists | AMIT_EGF_RESPONSE_20_HELA | 12 | 8 | 15632 | 1249 |
Gadd45b,Zc3h12a,Fos,Ppp1r15a,Jun,Pilrb1,Btg2,Pilrb2 |
| 6.042e-07 | -14.32 | CARD | prosite domains | PS50209 | 24 | 11 | 13278 | 1037 |
Nod1,Ripk2,Casp4,Casp1,Nlrc4,Apaf1,Birc3,Nod2,Card6,Casp2,Birc2 |
| 6.061e-07 | -14.32 | Signaling by the B Cell Receptor (BCR) | REACTOME pathways | R-MMU-983705 | 201 | 40 | 8608 | 757 |
Rictor,Psme2b,Src,Lyn,Ppp2r5a,Irs2,Phlpp2,Kitl,Cdkn1a,Pdgfb,Nfkb1,Syk,Ppp2r1b,Cd86,Nr4a1,Nfkbib,Nfkbia,Pdgfrb,Psmd10,Malt1,Phlpp1,Psme2,Psma6,Cd80,Trib3,Psmb10,Nck1,Ikbkg,Mdm2,Met,Psmb8,Ier3,Psme1,Psmb6,Rel,Itpr1,Pik3cd,Rasgrp1,Nfkbie,Psmb9 |
| 6.074e-07 | -14.31 | GSE17721_CTRL_VS_PAM3CSK4_2H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_2H_BMDC_DN | 187 | 36 | 15632 | 1249 |
Ets2,Ttc39c,Arhgef3,Sod2,Ehd1,Spn,Map3k6,Dtnb,Cp,Parp14,Edn1,Tpx2,Irs2,Lif,Clec4e,Prdx1,Traf5,Pilra,Med21,Slfn4,Samsn1,Hap1,Mmd,Plscr1,St3gal5,Flnb,Icosl,Arid5b,Cxcl10,Ptgs2,Osgin2,Slc31a1,Rnf19b,Il1rn,Slfn3,Cflar |
| 6.074e-07 | -14.31 | GSE17721_LPS_VS_POLYIC_8H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_8H_BMDC_DN | 187 | 36 | 15632 | 1249 |
Hp,Prdm9,Ldha,Itga9,Tmem229b,Arid5b,Tlr2,Gca,Asf1a,Lhx2,Dio2,Epsti1,Tfec,Birc3,S100a8,Ahrr,Irf7,Stat4,Il18rap,Oas2,Ddx60,Lrp8,Mcoln2,Usp18,Pgm1,Isg15,Fgr,Rbm43,Zbp1,Samhd1,Trmt1l,Homer1,Bcl6,Tiparp,Top3a,Ythdf1 |
| 6.090e-07 | -14.31 | sequence-specific double-stranded DNA binding | molecular function | GO:1990837 | 915 | 103 | 20217 | 1400 |
Ifi203,Egr2,Rel,Hinfp,Irf4,Relb,Etv5,Tcf4,Hhex,Ifi205,Fubp1,Stat5a,Irf8,Ikzf1,Hmga2,Spic,Tfec,Bcor,Sp140,Prdm9,Etv6,Ier2,Max,Nr1h3,Nr4a1,Sirt1,Nlrc5,Lmo4,Mafk,Prdm1,Irf7,Fosb,Mcm9,Pbx1,Nfkb1,Cebpd,Ifi211,Hdac1,Stat1,Etv3,Mcm6,Eno1,Zbtb5,Maff,Rfx5,Myc,Kdm6b,Stat3,Irf1,Hivep2,Ahr,Stat2,Hmga1,Pcgf5,Ifi207,Ifi208,Hif1a,Batf2,Stat4,Lhx2,Nfxl1,Batf,Pou2f2,Nfkb2,Mycl,Dach1,Ifi214,Kdm5b,Nr4a3,Fos,Mxd1,Zeb1,H3f3b,Jarid2,Bcl6,Aebp2,Jdp2,Arid5b,Mafg,Mndal,Klf6,Klf3,Tal2,Ifi209,Plagl1,Zfp281,Kat2b,Atf3,Egr1,Irf2,Notch1,Mcm10,Foxp4,Jun,Ifi204,Nfil3,Ifi213,Ets2,Nr3c1,Klf8,Junb,Klf7,Egr3 |
| 6.130e-07 | -14.30 | GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN | MSigDB lists | GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN | 134 | 29 | 15632 | 1249 |
Ccl5,Card6,Abtb2,Ifit1bl2,Gem,Plk2,Cav1,Plscr1,Akt3,Kif5c,Dyrk2,Ier3,Ccl4,Chd9,Rgs1,Arf4,Il1b,Psip1,Casp1,Ifit1bl1,Parp8,Nr3c1,Samd9l,Mafk,Aim2,Ddx60,Ifih1,Pttg1,Nkiras1 |
| 6.161e-07 | -14.30 | BROWNE_HCMV_INFECTION_8HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_8HR_UP | 92 | 23 | 15632 | 1249 |
Sec24a,Tnfsf10,Kitl,Mark2,Samhd1,Max,Crkl,Pim2,Oas1g,Icam1,Cxcl10,Nr4a3,Pla2g4a,Irf4,Isg20,Dusp8,Oas1a,Oas2,Ccne1,Sod2,Abcc5,Fos,Dnaja1 |
| 6.214e-07 | -14.29 | intracellular receptor signaling pathway | biological process | GO:0030522 | 99 | 22 | 20694 | 1406 |
Rnf34,Daxx,Irgm2,Tifa,Ripk2,Stat3,Src,Nr3c1,Nfkbia,Nr4a1,Pdk3,Pml,Jak2,Crkl,Ifih1,Dnaja1,Nr4a3,Ddx58,Pim1,Ahr,Nod2,Nr1h3 |
| 6.248e-07 | -14.29 | GSE13522_WT_VS_IFNAR_KO_SKIN_DN | MSigDB lists | GSE13522_WT_VS_IFNAR_KO_SKIN_DN | 164 | 33 | 15632 | 1249 |
Cd74,Prnp,Klf8,Atp2b4,Ahr,Ttc39c,Itpr1,Axl,Eif2ak2,Casp1,Fgl2,Cpd,Gpr68,Mlkl,Ccr3,Gbp4,Gbp9,Odc1,Grina,Lyn,Smox,Traf3ip2,Osbpl3,Cldnd1,Adam19,Tnfsf10,Vps54,Ccr1,Tnfrsf1b,Stx11,Srxn1,Flnb,Plscr1 |
| 6.248e-07 | -14.29 | GSE4984_UNTREATED_VS_GALECTIN1_TREATED_DC_UP | MSigDB lists | GSE4984_UNTREATED_VS_GALECTIN1_TREATED_DC_UP | 164 | 33 | 15632 | 1249 |
Zfp36,Slpi,Pdlim7,Vasp,Etv6,Rhou,S100a8,Cflar,Vcam1,Jak2,Igf2bp2,Rnf19b,Cpeb4,Mafg,Lyn,Fpr1,Kcnj2,Gpr84,Igsf6,Glipr2,Gsr,Aoah,Rab32,Dse,Zyx,Klf7,Aff1,Atp2b4,Egr1,Tlr6,Upp1,Slco3a1,Arl4a |
| 6.248e-07 | -14.29 | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_UP | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_UP | 164 | 33 | 15632 | 1249 |
Plcl2,Notch2,Cmpk2,Gfi1,Ebi3,Etnk1,Xkr8,Ptger4,Rilpl1,Isg20,Gpr132,Hivep3,Pou2f2,Parp12,Etv6,Rasgrp1,Spint2,Pde4b,Nfkb1,Brd2,Asah2,Lcp2,Vps54,Crlf3,Mvp,Plk3,St3gal3,Parp14,Cdyl2,Plac8,Gypc,Gpr18,Znfx1 |
| 6.303e-07 | -14.28 | GO_NIK_NF_KAPPAB_SIGNALING | MSigDB lists | GO_NIK_NF_KAPPAB_SIGNALING | 79 | 21 | 15632 | 1249 |
Nfkb1,Psmb8,Birc3,Birc2,Rel,Psmb9,Psmd10,Traf2,Tnfsf15,Psme2,Psma6,Tlr6,Psmb6,Malt1,Psme1,Tlr3,Psmb10,Nfkb2,Ikbke,Relb,Ripk3 |
| 6.395e-07 | -14.26 | GROSS_HYPOXIA_VIA_ELK3_ONLY_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_ONLY_UP | 33 | 13 | 15632 | 1249 |
Rabgef1,Dhrs9,Slc7a11,Ppp1r15a,Il6,Slpi,Rapgef2,Egln3,Ch25h,Rnd3,Cxcl1,Clec4e,Nfil3 |
| 6.402e-07 | -14.26 | KEGG_CELL_ADHESION_MOLECULES_CAMS | MSigDB lists | KEGG_CELL_ADHESION_MOLECULES_CAMS | 127 | 28 | 15632 | 1249 |
Vcam1,Nlgn2,H2-Ab1,Itga9,H2-Aa,Icosl,H2-Eb1,Cd86,Itgal,Cd274,Cd80,Cd34,Sdc4,Itga4,H2-Q7,Sell,F11r,Icam1,Sdc1,Itgb8,Sdc2,Sele,Vcan,Itgav,Spn,H2-Q4,Cd40,H2-Q6 |
| 6.470e-07 | -14.25 | regulation of necrotic cell death | biological process | GO:0010939 | 27 | 11 | 20694 | 1406 |
Rnf31,Bnip3,Birc2,Peli1,Cflar,Casp8,Birc3,Tspo,Cav1,Ripk3,Ahr |
| 6.550e-07 | -14.24 | GSE20727_ROS_INH_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP | MSigDB lists | GSE20727_ROS_INH_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP | 172 | 34 | 15632 | 1249 |
Socs3,Cpeb4,Dram1,Mafg,Serpinb9,Frmd4a,Tnip3,Trib1,Pim1,Rbms1,H3f3b,Card6,Nampt,Adap2,Gna15,Tlr1,Btg2,Hlx,Jmjd6,Arg2,Fpr2,Ube2f,Sgcb,Batf,Pfkfb3,Rhoc,Hk3,Plod3,Ptpn2,Gpr18,Dse,Lrch1,Katna1,Kremen1 |
| 6.550e-07 | -14.24 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN | 172 | 34 | 15632 | 1249 |
Pla2g7,Rapgef2,Cxcl2,H2-Aa,Htra1,Antxr1,Slpi,Il10,Lcp2,Marco,Pid1,Klf2,Dach1,S100a8,Adam19,Slamf8,Tgfbi,Clec5a,Fpr1,Etnk1,Mmp9,Glipr2,Fcgr2b,Mmp14,Bcl6,Dock4,Jun,Cst7,Hk3,Hvcn1,Me1,Cd14,Prnp,Rhoh |
| 6.579e-07 | -14.23 | regulation of mononuclear cell migration | biological process | GO:0071675 | 50 | 15 | 20694 | 1406 |
Ccl5,Cx3cl1,Csf1,Pla2g7,Serpine1,Lyn,Dusp1,Cxcl10,Cmklr1,Ptprj,Ccr1,Fpr2,Ccl2,Thbs1,Slamf8 |
| 6.596e-07 | -14.23 | GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 120 | 27 | 15632 | 1249 |
Atm,Plk2,Cenpj,Mndal,Btg2,Ifi211,Ddit4,Ifi208,Sirt1,Casp2,Ifi203,Dyrk2,Ifi204,Cdkn1a,Ifi213,Ifi209,Ifi205,Mdm2,Cnot4,Plk3,Nupr1,Pml,Plagl1,Ifi214,Batf,Ifi207,Tnks1bp1 |
| 6.663e-07 | -14.22 | GO_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | MSigDB lists | GO_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | 106 | 25 | 15632 | 1249 |
Nlrp3,H2-Q7,Malt1,Tap1,Ripk3,Cd40,Bcl6,H2-Q6,Traf2,Tnf,H2-Q4,Spn,Ifnb1,Rsad2,Il12b,Serpinb9,C3,Tnfsf4,Il1b,Clcf1,Pik3r6,Il10,Fzd5,Rasgrp1,Il12rb1 |
| 6.782e-07 | -14.20 | GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_UP | 180 | 35 | 15632 | 1249 |
Tnfrsf1b,Hopx,Marco,Irf7,Ksr1,Ddit4,Rtn2,Timeless,Pou2f2,Cxcl2,Casp2,Adora2a,Gng4,Dusp5,Il12b,Cxcl1,H3f3b,Cx3cr1,Apobec3,Slc16a3,Plod3,Ifnar1,Gypc,Rgs14,Sele,Ccnd1,Pcx,Rnf139,Stat2,Pttg1,Isg15,Aldh1b1,Traf1,Mapkbp1,Tap1 |
| 6.804e-07 | -14.20 | GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 142 | 30 | 15632 | 1249 |
Cysltr2,Rab10,Pdgfb,Plscr1,Birc3,Ccl5,Il10,Lrrc25,Jak2,Idi1,Gcnt2,Igf1r,Rnf19b,Denr,Kcna3,Itga9,Pim1,Cish,Fgl2,Hsph1,Sbds,Ttc39c,Psmb9,Cd40,Herc3,Batf,Lipg,Gbp2,Fas,Mxd1 |
| 6.818e-07 | -14.20 | Toll Like Receptor 7/8 (TLR7/8) Cascade | REACTOME pathways | R-MMU-168181 | 79 | 22 | 8608 | 757 |
Nfkb1,Tlr9,Map2k4,Nod2,Tab2,Fos,Peli1,Map3k8,Nfkbia,Nfkbib,Ppp2r1b,Ripk2,Ikbkg,Irf7,Myd88,Nfkb2,Nod1,Irak2,Mapkapk2,Jun,Dusp6,Dusp4 |
| 6.818e-07 | -14.20 | MyD88 dependent cascade initiated on endosome | REACTOME pathways | R-MMU-975155 | 79 | 22 | 8608 | 757 |
Ppp2r1b,Nfkbib,Nfkbia,Map3k8,Peli1,Fos,Tab2,Nod2,Nfkb1,Map2k4,Tlr9,Dusp4,Jun,Dusp6,Mapkapk2,Nod1,Irak2,Nfkb2,Myd88,Irf7,Ikbkg,Ripk2 |
| 6.847e-07 | -14.19 | GO_CELLULAR_RESPONSE_TO_PEPTIDE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_PEPTIDE | 261 | 45 | 15632 | 1249 |
Edn1,Nod2,Ccl12,Ass1,Nr4a1,Klf3,Ptpn2,Pde3b,Gng11,Irs2,Phip,Kat2b,Slc9a1,Nfkb1,Casp4,Cav1,Jak2,Gfpt1,Socs7,Prkar2b,Igf1r,Max,Ptk2,Lyn,Rhoq,Stat3,Errfi1,Mdm2,Stat5a,Klf6,Src,Gnb4,Nod1,Agtrap,Hif1a,Rab10,Fzd1,Nampt,Atp6v1d,Klf2,Gng12,Ripk2,Gng4,Nr4a3,Trib3 |
| 6.957e-07 | -14.18 | MODULE_27 | MSigDB lists | MODULE_27 | 347 | 55 | 15632 | 1249 |
Tnfrsf8,Cd14,H2-Q7,Calcrl,Cd180,Icam1,Itgb8,Tnc,Axl,Csf3r,Cd40,H2-Q6,Htr2b,Plaur,Il15ra,Tlr3,Ptafr,Fpr1,Il2rg,Tlr1,Adora2a,Il12rb1,H2-Eb1,Ccr1,Pdgfrb,Cd86,Fzd5,Cd80,Fcgr1,Ciita,Olr1,Ahr,Fas,Il4ra,P2ry14,Cdk5r1,Fpr2,Ccl2,Igsf6,S1pr2,Ccl12,Cx3cr1,H2-Q4,Ldlr,Cdkn1a,Itga5,Il13ra1,Tlr2,Adrb2,Lpar1,Itga9,Cd69,Tnfrsf1b,Ednrb,Itgal |
| 7.040e-07 | -14.17 | GO_MYELOID_LEUKOCYTE_MIGRATION | MSigDB lists | GO_MYELOID_LEUKOCYTE_MIGRATION | 86 | 22 | 15632 | 1249 |
Pdgfb,Cxcl2,S100a8,Pde4b,Ednrb,Ccl5,Ccl4,Trem1,Il1b,Itga9,Pik3cd,Edn1,Il6,Ccl2,Flt1,Cx3cr1,Syk,Ccl12,Csf3r,Ccl3,Ccl22,Cx3cl1 |
| 7.045e-07 | -14.17 | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 196 | 37 | 15632 | 1249 |
Jarid2,Rabgef1,Ppp1r15a,Nmi,Kdm6b,Cd55,Trib1,Mthfd2,Map3k8,Acsl1,Ptafr,Mmp25,Orai2,Notch2,Bcl2a1a,Thbs1,Snn,Aoah,Ehd1,Slc7a11,Bcl2a1b,Txnrd1,Acpp,Swap70,Fos,Bcl6,Stap1,Rhoq,Rnf24,Peli1,Arhgap26,Bcl2a1d,Pgs1,Fgr,Sla,Hk3,Mcmbp |
| 7.069e-07 | -14.16 | neurogenesis | biological process | GO:0022008 | 1769 | 172 | 20694 | 1406 |
Myc,Itga4,Prag1,Zeb1,Clic5,Rac3,Etv6,Dync1i2,Ptk2,Tsku,Ntng2,Sipa1l1,Stap1,Triobp,Sema4c,D16Ertd472e,Spen,Socs7,Ifrd1,Csf1,Lrp8,Fas,Igsf9,Flrt2,Adgrg6,Ccl2,Hdac1,Ust,Evl,Ddit4,Sdc2,S100a8,Cx3cr1,Rab21,Cnp,Kif5c,Tnc,Kif3c,Mecp2,Plpp3,Tulp3,Mov10,Vegfc,Adora2a,Tspo,Ehd1,Tnfrsf1b,Scarf1,Notch1,Rgs14,Gfi1,Flrt3,Jak2,Rap1gap2,Sphk1,Crkl,Tlr2,Inhba,Stat3,Sema3c,Map4k4,Nr3c1,Ptprj,Eif4g2,Ldlr,Map2k1,Dock10,Micall2,Fpr2,Hap1,Lst1,Vcan,Scn1b,Dst,Lif,Pdgfb,Gpc1,Lrp4,Lpar1,Mul1,Ednrb,Actb,Slc4a7,Sec24b,Bcl6,Fabp7,Rnd1,Agrn,C3,Pou3f1,Mark2,Ext1,Tmem67,Vcam1,Mosmo,Nlgn2,Mycl,Igf1r,Psd,Ccl5,Rab10,Uchl1,Zhx2,Kat2b,Ikzf1,Met,Nck1,Prdm1,Katna1,Etv5,Ccl12,Sdc4,Fcgr2b,Stxbp1,Egr2,Kdr,Cx3cl1,Zswim4,Tnf,P2ry2,Ccl3,Jun,P2ry12,Tcf4,Sod2,Fzd1,Palld,Sirt1,Btg2,Mdm2,Arf4,Il1b,Ppp2r3a,Hmga2,Il15ra,Axl,Fubp1,Ptch1,Itpr1,Lmo4,Gja1,Casp3,Dbnl,Pbx1,Clcf1,Nr4a3,Spire1,Cdk5r1,Klf7,Cav1,Lyn,Kremen1,Nrp2,Cd38,Rapgef2,Plk2,Lhx2,Bmp2,Sema4a,Casz1,Hif1a,Il6,Cyfip1,Kdm4a,Phgdh,Jag1,Syne2,Vasp,Mmd,Mturn,Ier2,Cflar |
| 7.197e-07 | -14.14 | positive regulation of chemotaxis | biological process | GO:0050921 | 140 | 27 | 20694 | 1406 |
Edn1,Cxcl14,Tnfsf14,Ccl5,Csf1,Pla2g7,Sell,Serpine1,Pdgfrb,Swap70,Il1b,Cd74,Kdr,Ccl4,Cxcl10,Cmklr1,Pdgfb,Vegfc,Cx3cl1,P2ry12,Lpar1,Met,Ccl2,Thbs1,Ptprj,Ccr1,Fpr2 |
| 7.229e-07 | -14.14 | PARP_CATALYTIC | prosite domains | PS51059 | 16 | 9 | 13278 | 1037 |
Parp11,Parp14,Zc3hav1,Parp12,Parp10,Parp3,Parp9,Parp8,Tiparp |
| 7.229e-07 | -14.14 | SMALL_CYTOKINES_CC | prosite domains | PS00472 | 16 | 9 | 13278 | 1037 |
Ccl2,Ccl9,Ccl3,Ccl4,Ccl22,Ccl8,Ccl12,Ccl5,Ccl7 |
| 7.261e-07 | -14.14 | GO_CHEMOKINE_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_CHEMOKINE_MEDIATED_SIGNALING_PATHWAY | 55 | 17 | 15632 | 1249 |
Ccl22,Cxcl10,Cx3cl1,Ccl3,Xcr1,Pf4,Cxcl1,Cmklr1,Ccl4,Ccr1,Cx3cr1,Ccl12,Ccl5,Ccrl2,Cxcl2,Ccr3,Ccl2 |
| 7.261e-07 | -14.14 | GO_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 55 | 17 | 15632 | 1249 |
Batf,Ifna1,Clec4e,Relb,Ifna2,Ptger4,Icam1,Il12b,Clec4d,Sema4a,Irf4,Ifna6,Il6,Ifna5,Ifnb1,Itgal,Cd86 |
| 7.261e-07 | -14.14 | LIAN_LIPA_TARGETS_3M | MSigDB lists | LIAN_LIPA_TARGETS_3M | 55 | 17 | 15632 | 1249 |
Cxcl1,Clec4e,Rgs1,Tnfaip2,Hmox1,Clec4d,Fabp7,Fcgr2b,Slc15a3,Igsf6,Pla2g7,Clec4n,Ccr1,Gdf15,Msr1,Spic,Marco |
| 7.263e-07 | -14.14 | regulation of peptidyl-serine phosphorylation | biological process | GO:0033135 | 157 | 29 | 20694 | 1406 |
Spry2,Cav1,Mtcp1,Osm,Rictor,Ifnb1,Phip,Txn1,Plcl2,Ifna1,Ppp1r15a,Ripk2,Irgm2,Ifna4,Ptgs2,Tnf,Il6,Lif,Atp2b4,Ifna2,Ifna5,Ddit4,Hcls1,Ifna6,Nck1,Tnks1bp1,Angpt1,Csf3,Met |
| 7.267e-07 | -14.13 | REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE | MSigDB lists | REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE | 67 | 19 | 15632 | 1249 |
Dusp4,Nod2,Nfkbib,Map2k1,Jun,Fos,Ikbkg,Dusp6,Nfkbia,Ppp2r1b,Irak2,Cd14,Nfkb2,Nod1,Map2k4,Tab2,Mapkapk2,Ripk2,Tlr3 |
| 7.431e-07 | -14.11 | KEGG_P53_SIGNALING_PATHWAY | MSigDB lists | KEGG_P53_SIGNALING_PATHWAY | 61 | 18 | 15632 | 1249 |
Fas,Ccnd2,Thbs1,Cd82,Apaf1,Cdkn1a,Gadd45b,Atm,Ccne1,Sesn3,Serpine1,Casp8,Cycs,Casp3,Mdm2,Ccnd1,Gadd45g,Ccng2 |
| 7.538e-07 | -14.10 | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 173 | 34 | 15632 | 1249 |
Cxcl1,Cldnd1,Pfkl,Fam162a,C3,Acvr1b,Slc43a3,Mafg,Sap30,Arl5b,Nfkbib,G3bp2,Maff,Tnfrsf1b,Rel,Ppp1r15a,Sav1,Slamf7,Ube2f,Tnfrsf8,Tnfrsf14,Tpi1,Icam1,Traf1,Sphk1,Setdb2,Nfkbie,Mllt6,Psma6,Gadd45b,Hivep2,Sod2,Itpr1,Mgat1 |
| 7.538e-07 | -14.10 | GO_RESPONSE_TO_CORTICOSTEROID | MSigDB lists | GO_RESPONSE_TO_CORTICOSTEROID | 173 | 34 | 15632 | 1249 |
Hif1a,Sdc1,Fas,Ahr,Notch1,Fos,Ass1,Ccl12,Tnf,Src,Dusp1,Ifnb1,Acvr1,Errfi1,Ccnd1,Il6,Edn1,Casp3,Nr3c1,Pla2g4a,Ptafr,Adrb2,Ptgs2,Socs3,C3,Il1b,Cdkn1a,Il1rn,Fosb,Cav1,Il10,Ccl5,Ccne1,Junb |
| 7.538e-07 | -14.10 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_DN | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_DN | 173 | 34 | 15632 | 1249 |
Ell2,Grina,Gpd2,Azi2,Trem1,Plaur,Armc8,Pmepa1,Slc31a2,Snx10,Serpine1,Plod2,Htra1,Pdlim7,Sh3bp4,Stx6,Nek6,Nupr1,Zfp281,Pttg1,Gbe1,Arl4a,Gnb4,Olfml3,Olr1,Tle3,Dusp1,Nfkbia,Itgav,Sat1,Gpr84,Rffl,Chst11,Cpd |
| 7.574e-07 | -14.09 | GO_REGULATION_OF_INTERLEUKIN_6_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_6_PRODUCTION | 93 | 23 | 15632 | 1249 |
Il10,Klf2,Rabgef1,Tlr1,Ptafr,Tlr2,Adora2b,Ripk2,Zc3h12a,Tlr9,Tlr3,Tnfsf4,Il1b,Tnf,Nod2,Il6,Ddx58,Mapkapk2,Tlr6,Irak3,Tnfaip3,Nod1,Myd88 |
| 7.593e-07 | -14.09 | MARTINEZ_TP53_TARGETS_UP | MSigDB lists | MARTINEZ_TP53_TARGETS_UP | 549 | 77 | 15632 | 1249 |
Nr4a1,Klf3,Morc3,Rnf114,Itgav,Tspan3,Msr1,Fos,Fcgr2b,Prokr1,Bnip3,Ikzf1,Prkce,Cnot4,Ncoa5,Cpd,Pcx,Cxcl14,Atf3,Ccnd2,Coa5,Pttg1,Arrdc4,Pilra,Pfkfb3,Prdx1,Slc48a1,Clec4e,Me1,Ahr,S100a8,Rnf14,Tnfsf14,Hdc,Trip13,Alas1,Dram1,Itga9,Trib1,Ms4a6d,Acsl1,Ier3,Rbms1,Clcf1,Fscn1,Actb,Esd,Fam162a,Cdkn1a,Lrrc8c,Pmepa1,Dusp1,Lipe,Abcc5,Serp1,Nr3c1,Cp,Fgl2,Rsad2,Magohb,Itga4,Cd74,Pdgfc,Gja1,H2-Aa,Car13,Wars,Tgfbi,Ptgs2,Nsmaf,Mcm6,Il2rg,Thbs1,Serpinb2,Glrx,Tcea1,Hcar2 |
| 7.599e-07 | -14.09 | positive regulation of leukocyte mediated cytotoxicity | biological process | GO:0001912 | 85 | 20 | 20694 | 1406 |
Tap2,H2-Q7,H2-Q4,Cxcl1,Stat5a,H2-T22,H2-T10,Stap1,Klrk1,Raet1e,Nectin2,Il18rap,Il12b,Rasgrp1,H2-Q6,H60b,Pvr,Ccl2,H2-M2,H2-T24 |
| 7.642e-07 | -14.08 | GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | MSigDB lists | GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | 24 | 11 | 15632 | 1249 |
Tnfsf4,Hlx,Il4ra,Bcl6,Nlrp3,Cd74,Cd86,Il6,Rsad2,Ifnb1,Nod2 |
| 7.756e-07 | -14.07 | positive regulation of peptidyl-serine phosphorylation | biological process | GO:0033138 | 124 | 25 | 20694 | 1406 |
Ifna6,Tnks1bp1,Csf3,Angpt1,Met,Hcls1,Il6,Atp2b4,Lif,Ifna2,Ifna5,Ripk2,Irgm2,Ifna4,Ptgs2,Tnf,Ifna1,Ppp1r15a,Txn1,Phip,Cav1,Spry2,Osm,Ifnb1,Mtcp1 |
| 7.775e-07 | -14.07 | GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN | MSigDB lists | GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN | 181 | 35 | 15632 | 1249 |
Rnf14,Nfkbib,Sap30,Maff,Sirt1,G3bp2,Wars,Usp12,Dusp5,Zc3h12a,Itpkc,Mmp9,Scyl2,Kpna3,Nr4a3,Pim1,Irf1,Ak4,Rcl1,Plekhf2,Abcc5,Hsph1,Jun,Serp1,D1Ertd622e,Stat3,Gclm,Cnot4,Atf3,Socs1,Sertad3,Icam1,Cutc,Bfar,Relb |
| 7.775e-07 | -14.07 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_DN | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_DN | 181 | 35 | 15632 | 1249 |
Cx3cr1,Nfkbia,Ppp1r14b,Cst7,Dse,Acpp,Ctsc,Spry2,Phgdh,Arhgap26,Nfkbie,Icam1,Gbp3,Cd38,Slc28a2,Ahr,Tnfrsf1b,Rnaset2a,Plscr1,Ccrl2,Il18rap,Tdrd7,Ptprj,Rnf19b,Egr3,Smox,Mafg,Lyn,Serpinb9,Nsmaf,Adam19,Tnfsf10,Rnaset2b,5430427O19Rik,Socs7 |
| 7.842e-07 | -14.06 | negative regulation of blood vessel morphogenesis | biological process | GO:2000181 | 116 | 24 | 20694 | 1406 |
Notch1,Hhex,Rgcc,Pgk1,Serpine1,Spry2,Stat1,Klf2,Pml,Sema4a,Cx3cr1,Ccl2,Col4a2,Pf4,Adrb2,Thbs1,Plk2,Tcf4,Cxcl10,Spred1,Lif,Pde3b,Ptger4,Mecp2 |
| 7.876e-07 | -14.05 | protein dimerization activity | molecular function | GO:0046983 | 1400 | 144 | 20217 | 1400 |
Homer1,Jun,Nlrc4,Bcl2a1b,Itgav,Cacybp,Trim12c,Fbxo4,Pdgfc,H2-Ab1,Gclm,Nampt,Tpst1,Klrk1,Nr3c1,Ccl5,Tal2,Rasgrp1,Mpp7,Adora2a,Foxp4,Notch1,Nos2,Atf3,Timeless,Dr1,Hmgcs1,Ggct,Mxd1,Sqstm1,Ripk2,Glipr2,Rbpms,Gbp3,Fos,Srm,Nr4a3,Daxx,Mycl,Casp8,H2-Q4,Tap1,Acpp,Mafg,Jdp2,Prdx1,Nod1,Gbp2,Irak3,Hif1a,Mthfd1l,Acvr1,Tlr2,Pdgfb,Clcf1,Bnip3,Gdf15,Tlr1,Txnrd1,Cst7,Irak2,Bcl2l11,Fzd1,Hp,Stat3,Jmjd6,Myc,Mid1,Plek,Eno1,Hmox1,Slc39a13,Stat1,Cd69,Eno2,Hdc,Lrp4,Kif9,Ahr,Bcl2a1d,Lcn2,Tlr6,Odc1,Nfkb1,Pbx1,Keap1,Dgkh,Itgal,Tpi1,Atm,Snx2,Tap2,Dck,Hk1,Il12b,Axl,Met,Rilpl1,Ikbkg,Gbp2b,Cebpd,Asns,Prdx5,H2-Q6,Dst,Nectin2,Cav1,Taf4b,Chmp4b,Tfec,Katna1,H2-Q7,Gsr,Nr4a1,Nr1h3,Csf1,Bmp2,Pdss1,Max,Adrb2,Mitd1,Tpm4,Cflar,Nectin4,Slc16a1,Gclc,Ext1,Zhx2,Abtb2,Ahrr,Wars,Gch1,Gca,Ikzf1,Flrt3,Bcl2a1a,Il10,H2-Aa,Pml,Inhba,Pvr,Ptgs2,Tcf4,Hhex |
| 7.914e-07 | -14.05 | cytokine binding | molecular function | GO:0019955 | 130 | 26 | 20217 | 1400 |
Ccr1,Itgav,Itga4,Cx3cr1,Cd74,Xcr1,Il13ra1,Agrn,Zfp36,Il2rg,Il12rb1,Il18bp,Ebi3,Vasn,Acvrl1,Tnfrsf1b,Ifnar1,Il1rn,Tnfrsf14,Csf3r,Acvr1,Ccrl2,Pdpn,Ccr3,Thbs1,Il12b |
| 7.934e-07 | -14.05 | GSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 189 | 36 | 15632 | 1249 |
Me1,Ciita,Il15,Gnb4,Lpcat2,Gng11,Gpc1,Ccl22,Tmem176b,Chst11,Ccnd1,Dusp4,Pla2g4a,Pdpn,Rai14,Swap70,Timp1,Nfkbia,Casp1,Lpar1,Lyn,Il18,Rnf19b,Tmem26,Kctd12,Etv6,Alas1,Htra1,Tifa,Plscr1,Daam1,Asns,Casp4,Serpine1,Tor3a,Ltbp2 |
| 7.934e-07 | -14.05 | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | 189 | 36 | 15632 | 1249 |
St3gal1,Usp31,Adora2b,Phf6,Thbs1,Abcc1,Il15ra,Jdp2,Ppp1r15b,Rgl1,Dmwd,Col11a2,Klf2,Plscr1,Flnb,Gpr132,Inpp5b,Sap30,Hk2,Fam72a,Pml,Magohb,Rars,Sell,Atp11a,Pim3,Ripk3,Fam43a,Ets2,Spic,Ppp2r5a,Rab11fip1,Ikzf1,Minpp1,Mdm2,Ccnd1 |
| 7.934e-07 | -14.05 | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_DN | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_DN | 189 | 36 | 15632 | 1249 |
Pou2f2,Rasgrp1,Rap1gap2,St3gal5,Ddit4,Sipa1l1,Rims3,Itgal,Plek,Inpp1,Bcl2a1a,Trib1,Filip1l,Bcl2a1d,Cept1,Phlpp1,Ccnd1,Rhoq,Ly75,Gpr35,Stap1,Rhof,Abcc5,Sqstm1,Bcl2a1b,Nfkbia,Hck,Rgs3,Cd83,Nr1h3,Jmjd6,Traf1,Slc39a13,Rab19,Spata13,Nfkbiz |
| 7.955e-07 | -14.04 | GO_REGULATION_OF_INTERLEUKIN_2_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_2_PRODUCTION | 44 | 15 | 15632 | 1249 |
Traf2,Cd86,Pde4b,Ezr,Irf4,Prnp,Il1a,Tnfsf4,Malt1,Ripk2,Tnfaip3,Il1b,Cd34,Cd83,Cd80 |
| 7.955e-07 | -14.04 | GO_REGULATION_OF_INTERLEUKIN_12_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_12_PRODUCTION | 44 | 15 | 15632 | 1249 |
Irak3,Cmklr1,Thbs1,Irf1,Il12b,Tlr2,Mefv,Tlr3,Tnfsf4,Tlr9,Ripk2,Irf8,Il10,Cd40,Nfkb1 |
| 8.116e-07 | -14.02 | cellular homeostasis | biological process | GO:0019725 | 857 | 96 | 20694 | 1406 |
Marcksl1,Slc31a1,Jak2,Prdx5,Cxcl3,Gpr18,Hmox1,Swap70,Hk3,Ero1l,1600014C10Rik,Tmem178,Cxcl10,Mafg,Lpar1,Hap1,Fpr2,Lcn2,Xcr1,Pdk3,Ccrl2,Edn1,Gsr,Myc,Slc12a9,Htr2a,Ptk2,Ccr3,Ptgir,Ptger4,Atp2b4,Cmklr1,Cxcl1,Slamf8,Slc9a1,Adrb2,Slc30a1,Ccl2,Cx3cr1,Sco1,Glrx,Hk2,Slc39a4,Itpr1,Itgav,Gja1,Htr2b,Cav1,Slc31a2,Prkce,Sirt1,Grina,Txnrd1,Il1b,Slc39a14,Il6,Hif1a,Rmdn3,Lox,Gna15,Slc39a13,Mt1,Cd38,Dmxl2,Cacnb3,Prnp,Fbxo4,Clic4,Cd40,Atp13a1,Igf1r,Stxbp3,Nox1,Vcam1,Cxcl2,Ccl5,Hk1,Icam1,Bnip3,Slc4a7,Ednrb,Fpr1,Txn1,Gclc,Kdr,Cacna1d,Mt2,Cx3cl1,Ccl3,P2ry2,Prdx1,Gpr35,Rab20,Ccr1,Pml,Cp |
| 8.161e-07 | -14.02 | MARTINEZ_RB1_AND_TP53_TARGETS_UP | MSigDB lists | MARTINEZ_RB1_AND_TP53_TARGETS_UP | 550 | 77 | 15632 | 1249 |
Tgfbi,Ptgs2,Nsmaf,Mcm6,Il2rg,Parp3,Glrx,Hcar2,Tcea1,Thbs1,Serpinb2,Gja1,Tuba4a,Car13,Wars,H2-Aa,Cd74,Itga4,Pdgfc,Timp1,Serp1,Dusp1,Lipe,Abcc5,Fgl2,Rsad2,Nr3c1,Cp,Itga9,Trib1,Ms4a6d,Ier3,Acsl1,Dram1,Fam162a,Esd,Cdkn1a,Lrrc8c,Pmepa1,Rbms1,Clcf1,Fscn1,Actb,Tnfsf14,Hdc,S100a8,Rnf14,Egln3,Alas1,Pttg1,Ccnd2,Coa5,Arrdc4,Atf3,Me1,Ahr,Pilra,Pfkfb3,Prdx1,Tspo,Slc48a1,Clec4e,Msr1,Tspan3,Fos,Klf3,Nr4a1,Morc3,Rnf114,Itgav,Cnot4,Cpd,Pcx,Fcgr2b,Ikzf1,Bnip3,Prkce |
| 8.218e-07 | -14.01 | antigen processing and presentation of peptide antigen | biological process | GO:0048002 | 64 | 17 | 20694 | 1406 |
H2-Aa,H2-T10,H2-Eb1,H2-T22,Tap2,H2-Q7,H2-Q4,Fcgr1,H2-T24,H2-M2,H2-Ab1,H2-Q6,Cd74,Tapbpl,Tapbp,Tap1,Fcgr2b |
| 8.335e-07 | -14.00 | GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_UP | MSigDB lists | GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_UP | 166 | 33 | 15632 | 1249 |
Aida,Nsmaf,Stat1,Il13ra1,Nfil3,Gtpbp2,Rbms1,Tnfsf10,Rgl1,Ccr1,Hk1,Xaf1,Ppp2r3a,Trim14,Kat2b,Gbp3,Ahr,Samhd1,Gnb4,Myd88,Pnpt1,Ifit2,Slc16a3,Mllt6,Glipr2,Parp9,Samd9l,Casp3,Ubtd2,Egr2,Slc44a1,Il4i1,Batf2 |
| 8.335e-07 | -14.00 | GO_REGULATION_OF_CHEMOTAXIS | MSigDB lists | GO_REGULATION_OF_CHEMOTAXIS | 166 | 33 | 15632 | 1249 |
Ccl12,Ptpn2,Swap70,Stap1,Il6,Cxcl14,Cx3cl1,Cd74,Notch1,Ccl5,Ccr1,Pdgfrb,Serpine1,Sema3c,Tnfsf14,Pdgfb,Csf1,Cxcl2,Met,Pla2g7,Sema4c,Sema4a,Cxcl10,Lyn,Lpar1,Thbs1,Kdr,Ccl4,Cxcl1,Cmklr1,Il1b,Pf4,Vegfc |
| 8.335e-07 | -14.00 | GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_IN_SLE2C1_MOUSE_DN | MSigDB lists | GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_IN_SLE2C1_MOUSE_DN | 166 | 33 | 15632 | 1249 |
Ccr1,Txn1,Tnfsf14,Sema3c,Samsn1,Ksr1,Dcp1a,Eya4,Nfkbid,Cd200,Ptger4,Acsl1,Pcdh7,Fscn1,Whamm,Bcl2a1a,Bcl2a1b,Gadd45b,Nfkbia,Casz1,Serp1,Arid5a,Otud1,Il6,Il4i1,Bcl2a1d,Pikfyve,Ccl22,Cd80,Tnfrsf8,Slc16a1,Sgcb,Kif9 |
| 8.335e-07 | -14.00 | SASAKI_ADULT_T_CELL_LEUKEMIA | MSigDB lists | SASAKI_ADULT_T_CELL_LEUKEMIA | 166 | 33 | 15632 | 1249 |
Ifi209,Ifi205,Ifi213,Hdac1,Irf4,Pttg1,Isg15,Tpx2,Ifi214,Sell,Fas,Aim2,Ifi207,Extl2,Prdx1,Batf,Daam1,Cav1,Mndal,Ifi203,Oas2,Isg20,Ifi211,Sap30,Ifi208,Nmi,Ifi204,Trib1,Ptprj,Stat1,Parp3,Trafd1,Ust |
| 8.368e-07 | -13.99 | interspecies interaction between organisms | biological process | GO:0044419 | 287 | 43 | 20694 | 1406 |
Mmp9,Zc3h12a,Gsdmd,Nectin4,Cd300lf,Myc,Nectin2,Chmp4b,Axl,Cd55,Vcam1,Itgav,Zbp1,Icam1,Ripk3,Tlr2,Ccl5,Serpinb9,Tnip1,Pcx,Tnfrsf14,Cav1,Bcl2l11,Trem1,Ccl2,Rab9,Clec5a,Irgm1,Pf4,Hdac1,Gbp2,Gbp3,Pml,Denr,Pvr,Gbp9,Gbp2b,Gbp7,Ccl4,Slpi,Mecp2,Irgm2,Jun |
| 8.372e-07 | -13.99 | MODULE_55 | MSigDB lists | MODULE_55 | 763 | 99 | 15632 | 1249 |
Gadd45b,Nr4a1,Cited2,Ets2,Gclm,Gadd45g,Dtnb,Psd,Col18a1,Cx3cl1,Aldh1b1,Cdk5r1,Sdc1,Fpr2,F10,Dnase1l3,Ikbkg,Tnfrsf1b,S100a8,Cav1,Ppp4r2,Alas1,Slpi,Nfkbib,Pou2f2,Itga5,Pim2,Rac3,Trib1,Ldlr,Adam19,Nfil3,Dnajb2,Csf3r,Cp,Hspa2,Sele,Nupr1,Plk3,Rnd1,Atp11a,Cd14,Gdf15,Dusp6,Psd4,Serpine1,Ddit4,Hmox1,Hp,Il2rg,Phyh,Plat,Slc7a11,Ccl12,Ifit1bl1,Flt1,Zyx,Fos,Stard5,Nqo1,Egr1,Il4ra,Ccnd2,Pttg1,Etv3,Gclc,Pfkfb3,Plau,Angpt1,Tnfrsf14,P4ha1,Lcn2,Casp2,Ell2,Ier3,Acsl1,Cst7,Ccnd1,Lif,Mthfr,Nfkbil1,Isg15,Crim1,Gch1,Slc7a8,Ifit1bl2,Junb,Phlda1,Ube2l6,Hap1,Stoml1,Cd55,Smox,Ak4,Tgfbi,Tnfsf10,Il1rn,Glrx,Gng12 |
| 8.473e-07 | -13.98 | regulation of protein modification by small protein conjugation or removal | biological process | GO:1903320 | 230 | 37 | 20694 | 1406 |
Adrb2,N4bp1,Arrdc4,Fbxo4,Tank,Angpt1,Peli1,Birc3,Parp10,Caml,Nmi,Dcun1d3,Ripk2,Tspo,Mul1,Daxx,Ahrr,Gbp4,Dtx3l,Svbp,Zc3h12a,Trib3,Isg15,Gclc,Dnaja1,Sphk1,Birc2,Trim21,Nod2,Tnip1,Dnajb2,Trib1,Tnfaip3,Cav1,Psmd10,Prkce,Egr1 |
| 8.479e-07 | -13.98 | GO_REGULATION_OF_BODY_FLUID_LEVELS | MSigDB lists | GO_REGULATION_OF_BODY_FLUID_LEVELS | 485 | 70 | 15632 | 1249 |
Ptger4,Pf4,Plaur,Serpinb2,Thbs1,Plat,Pik3r6,Serpine1,Lcp2,Gja1,Csrp1,Plek,Hk2,Maff,Dgka,Adora2a,Mmp13,Stxbp3,Ifna6,Pdgfb,Hif1a,Irf2,Ifna2,Pdgfc,Cd40,P2ry12,Itpr1,Axl,Ehd1,Src,Stat5a,Hdac1,Ccnd1,Mafk,Mafg,Lyn,Adrb2,Irf1,C3,Dgkh,Prkar2b,H3f3b,Actb,Jak2,P2ry2,Gna15,Cav1,Ednrb,Plscr1,Procr,Nr1h3,Cx3cl1,Papss2,Ubash3b,Stxbp1,Enpp4,Ifna1,F10,Plau,Cd34,Pik3r5,Slc7a11,Syk,Ifnb1,Ifna5,Ap3b1,Il6,Pdpn,Prkce,Edn1 |
| 8.575e-07 | -13.97 | FORTSCHEGGER_PHF8_TARGETS_DN | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_DN | 685 | 91 | 15632 | 1249 |
Klf6,Dpy19l1,Ifit2,Slc25a37,Dhx58,Cdyl2,Nfkbie,Ifi44,Itgb8,Micall2,Ifih1,F11r,Slc39a13,Atp11a,Mvp,Rgs3,Pbx1,Gnb4,Ccl5,Spint2,Tbc1d13,Phlpp2,Ext1,Fcho2,Slc31a1,Pcgf5,Ptges,Pkp4,Tmem184b,Optn,Slc30a1,Kat2b,Dcp2,Pgm1,Zc3hav1,Cav1,Hk1,Isg20,Ifit3b,Dennd2a,Oasl1,Hmgcs1,Mtdh,Cpeb4,Frmd6,Mob3c,Ppp2r1b,Gbp2b,Cd82,Gfpt1,Arf4,Axl,Ehd1,Fut8,Isg15,Traf1,Ddx58,Relb,Tnfrsf8,Mapkbp1,Ifit1bl2,Phlda1,Kif3c,Mob3b,Ptger4,Glrx,Dio2,Gca,Elmod2,Osbpl3,Jun,Psmd10,Ifit1bl1,Hivep2,Map3k6,Il6,Edn1,Il4ra,Gbe1,P2ry2,Ifit3,Eno2,Birc3,Flnb,Procr,Fam111a,Ell2,Ebi3,Stard7,Agpat4,Tnip1 |
| 8.638e-07 | -13.96 | Activated TLR4 signalling | REACTOME pathways | R-MMU-166054 | 80 | 22 | 8608 | 757 |
Nfkb1,Map2k4,Nod2,Tab2,Fos,Peli1,Map3k8,Nfkbia,Nfkbib,Ppp2r1b,Ripk2,Ikbkg,Irf7,Myd88,Cd14,Nfkb2,Nod1,Irak2,Mapkapk2,Jun,Dusp6,Dusp4 |
| 8.659e-07 | -13.96 | proximal promoter sequence-specific DNA binding | molecular function | GO:0000987 | 578 | 72 | 20217 | 1400 |
Etv6,Zeb1,Mxd1,Fos,Nr4a3,Sp140,Mycl,Tfec,Dach1,Ifi214,Nlrc5,Nr1h3,Mafg,Nr4a1,Max,Aebp2,Jdp2,Hif1a,Batf2,Stat4,Hinfp,Irf4,Ifi208,Relb,Egr2,Ifi207,Ifi203,Nfkb2,Ikzf1,Spic,Batf,Pou2f2,Stat5a,Irf8,Lhx2,Tcf4,Hhex,Ifi205,Kdm6b,Stat3,Ets2,Jun,Ifi213,Nfil3,Ifi204,Maff,Rfx5,Myc,Stat1,Stat2,Klf7,Irf1,Hivep2,Klf8,Ahr,Junb,Nr3c1,Zfp281,Pbx1,Fosb,Ifi209,Mafk,Klf6,Prdm1,Irf7,Mndal,Foxp4,Notch1,Hdac1,Ifi211,Atf3,Cebpd |
| 8.705e-07 | -13.95 | GO_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | 74 | 20 | 15632 | 1249 |
Pf4,Kitl,Hcls1,Il12b,Isg15,Hif1a,Trib1,Acvr1b,Lif,Gpr68,Csf3,Jag1,Inhba,Csf1,Jun,Casp8,Fos,Ccl5,Ccr1,Tnf |
| 8.811e-07 | -13.94 | BAKER_HEMATOPOIESIS_STAT3_TARGETS | MSigDB lists | BAKER_HEMATOPOIESIS_STAT3_TARGETS | 16 | 9 | 15632 | 1249 |
Ccnd1,Il6,Myc,Pim1,Hif1a,Ccnd2,Fas,Pim2,Mmp9 |
| 8.811e-07 | -13.94 | LEE_LIVER_CANCER_HEPATOBLAST | MSigDB lists | LEE_LIVER_CANCER_HEPATOBLAST | 16 | 9 | 15632 | 1249 |
Plaur,Tnc,Il6,Fos,Ptgs2,Timp1,Ccnd2,Ezr,Nr4a1 |
| 8.837e-07 | -13.94 | Golgi apparatus | cellular component | GO:0005794 | 1381 | 140 | 20747 | 1409 |
Kdr,Irgm2,Cept1,Tlr2,Clcn5,Whamm,Ift57,Chst11,Golga3,Atp11a,Rnd3,Dbnl,Gbp2b,Mgat1,Rtn1,B3gnt5,Slc39a13,Adam19,Rab3ip,Plk3,Atp11b,Tpst1,Vcam1,Fzd5,Naa25,Rab32,Lipg,Tapbp,Bcl6,Kcnj2,Hp,Trip10,Plod3,Extl2,Mosmo,Gsap,Srgn,Ap3m2,St3gal1,Acpp,Plagl1,Gbgt1,Tent4a,Scyl2,Aftph,Map2k1,Fut8,Asah2,Pde3b,Rab19,Lyn,Grina,Nfkbie,Ptch1,Glipr2,Pmepa1,Rasgrp1,Ric1,Pdgfrb,Tapbpl,Hck,Mmp13,Stx6,Optn,Apba1,Ap3b1,Tgfbi,Pla2g4a,Ext1,Rab10,St3gal3,Gcnt2,Plpp3,Cd14,Myo1b,Rnf24,H2-Ab1,Prnp,Arf4,Ctsc,Lpcat2,St3gal6,Ust,St3gal5,Mtus1,Cav1,B4galt4,Fam20c,Dock4,Vps54,Chic2,Rab21,Irgm1,Fndc3a,Nod2,Mmd,Pgap2,Slc29a3,Gbp3,Prkce,Gdf15,Ppp1r15a,Cd74,Iigp1,H2-Q4,Cop1,Clic5,Lap3,Gbp2,Arl5b,Slc30a1,Marf1,Stx11,Serpinb9,Mppe1,Dse,Rhou,Gja1,Agtrap,Cxcl14,Vcpip1,Itga5,Cst7,H2-Q7,Rab20,Ccdc88b,Notch1,Sgms2,Fam241a,Spire1,Tlr6,Plscr1,Cpd,Nlrp3,Bcl9,Ldlr,Tlr1,Rab9,Arl5c,H2-Q6 |
| 8.900e-07 | -13.93 | GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 182 | 35 | 15632 | 1249 |
Rnf34,Gclc,Tnfaip3,Fas,Cdkn2d,Phip,Hif1a,Il1a,Icam1,Cd74,Cx3cl1,Gclm,Rffl,Acvr1,Src,Hsph1,Tnf,Cx3cr1,Sod2,Itgav,Traf2,Psmd10,Hspa1a,Cflar,Tnfsf10,Thbs1,Plaur,Il1b,Pf4,Mmp9,Hmox1,Grina,Sirt1,Casp8,Serpine1 |
| 8.986e-07 | -13.92 | GO_RESPONSE_TO_PROTOZOAN | MSigDB lists | GO_RESPONSE_TO_PROTOZOAN | 20 | 10 | 15632 | 1249 |
Il4ra,Cd40,Il12b,Il10,Irf8,Spn,Il6,Batf2,Batf,Irf4 |
| 9.021e-07 | -13.92 | GO_CELL_SURFACE | MSigDB lists | GO_CELL_SURFACE | 647 | 87 | 15632 | 1249 |
Treml2,Gsr,Hspa2,Acvrl1,Rab21,Itgb8,H2-Q6,P2ry12,Cd40,Tnf,Axl,Lrp4,Clmp,Notch1,Cd38,Pdgfc,Rhoc,Cd83,Bmp2,Lipg,Cd14,Icam1,Cd74,Sell,Intu,H2-Q7,Itga4,Vasn,Il12rb1,Fzd1,Pdgfb,Antxr1,Cd274,Cd86,Fzd5,Ccr1,H2-Eb1,Dcbld2,Vcam1,Thbs1,Plat,Clic4,Cldnd1,Clec5a,Spire1,Cxcl10,Il2rg,Ptprj,Cd55,Tlr3,Nod2,Sdc2,Ppfia3,Abcb1a,Pdpn,Il6,H2-Q4,Spn,Slc7a11,Itgav,Tnfrsf14,Plau,Cd34,Sdc4,F10,Il15,Cd80,Sdc1,Prnp,Cx3cl1,Fas,Cd69,Met,Procr,Slc9a1,Itgal,Cav1,Layn,Nlgn2,Notch2,Tmem123,Ldlr,Lpar1,Acvr1b,Tlr2,Tnfsf4,Itga5 |
| 9.050e-07 | -13.92 | GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | 190 | 36 | 15632 | 1249 |
Nr4a3,Pim1,Phf6,Grina,Socs3,Smox,Rnf19b,Rgs1,Tax1bp1,Osm,Dcun1d3,Nfkb1,Slc4a7,Rasgrp1,Car13,Sap30,Znrf3,Prnp,Csrnp1,Mapkapk2,H2-Q7,Mdfic,Aff1,Tmem184b,H2-Q6,Arhgef3,Tet2,Arid5a,H2-Q4,Dock10,Pcx,Cox17,Ap3b1,Cish,Myc,Irf4 |
| 9.113e-07 | -13.91 | GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | MSigDB lists | GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | 206 | 38 | 15632 | 1249 |
Lif,Parp10,Nfkbil1,Sphk1,Nlrp3,Ddx58,Prdx1,Mdfic,Angpt1,Nfkbia,Tnf,Psmd10,Il6,Rbpms,Nfkbie,Zc3h12a,Dyrk2,Tlr3,Tlr9,Il12b,Tlr2,Il18,Ptgs2,Bambi,Hcls1,Jak2,Cdkn1a,Keap1,Il1b,Txn1,Il10,Tnfsf14,Nfkbib,Slc9a1,Fzd1,Sirt1,G3bp2,Csf3 |
| 9.120e-07 | -13.91 | Interleukin-1 signaling | REACTOME pathways | R-MMU-446652 | 41 | 15 | 8608 | 757 |
Ikbkg,Il1rn,Nod2,Ripk2,Nfkb1,Myd88,Tab2,Irak3,Il1a,Peli1,Sqstm1,Irak2,Map3k8,Nod1,Il1b |
| 9.249e-07 | -13.89 | GO_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 29 | 12 | 15632 | 1249 |
Nfkbia,Ripk2,Ikbkg,Ddx58,Tab2,Casp8,Irf7,Ifih1,Nod1,Irak2,Nod2,Tnfaip3 |
| 9.266e-07 | -13.89 | Ripk1 (receptor (TNFRSF)-interacting serine-threonine kinase 1) | protein interactions | 19766 | 21 | 11 | 7778 | 753 |
Tnf,Ikbkg,Traf2,Il1b,Sqstm1,Ripk3,Tax1bp1,Tnfaip3,Tlr3,Casp8,Map3k8 |
| 9.279e-07 | -13.89 | WOO_LIVER_CANCER_RECURRENCE_UP | MSigDB lists | WOO_LIVER_CANCER_RECURRENCE_UP | 94 | 23 | 15632 | 1249 |
Tlk2,Dusp4,Ccl12,Tspan3,Rhof,Hmga1,Sgcb,Plau,Evl,Ccnd2,Plagl1,Socs1,Ext1,Jag1,Fzd1,Hk2,Eno2,Sema3c,Gem,Notch2,Rgs1,Plaur,Lox |
| 9.377e-07 | -13.88 | MKP | interpro domains | IPR008343 | 10 | 7 | 19984 | 1430 |
Dusp6,Dusp1,Dusp2,Dusp8,Dusp16,Dusp4,Dusp5 |
| 9.377e-07 | -13.88 | Chemokine_CXC_CS | interpro domains | IPR018048 | 10 | 7 | 19984 | 1430 |
Cxcl9,Cxcl2,Cxcl3,Cxcl10,Cxcl1,Pf4,Cxcl11 |
| 9.475e-07 | -13.87 | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | 413 | 62 | 15632 | 1249 |
Dnaja2,Kdm6b,Atp10a,Lox,Adora2b,Plat,Thbs1,Map4k4,Slc12a9,Slc4a7,Hsd17b12,Igsf8,Pdgfrb,Serpine1,Fosb,Tap2,Nrp2,Vasn,Plagl2,Rgs3,Abcc5,Usp53,Dusp1,P4ha2,Axl,Klf6,Slc2a1,Atp13a1,Tapbp,C1ra,Acvr1,Socs3,Itga5,Hmgcs1,Sema4c,Adrb2,Tlr2,Ldlr,Clcf1,Clcn7,Lrrc8c,Abcc1,H3f3b,Pfkl,Esd,Igf1r,P4ha1,Zfp36,Flnb,Bcl9,Slc39a14,Rictor,Pla2g7,Nfkbiz,Prnp,Adar,Slc16a1,Pim3,Klf3,Fos,Mmp14,Tra2a |
| 9.522e-07 | -13.86 | cellular extravasation | biological process | GO:0045123 | 39 | 13 | 20694 | 1406 |
Trem1,Ccl2,Itga4,Spn,Cx3cr1,Sele,Vcam1,Crkl,Tnf,Ccl5,Cx3cl1,Icam1,Sell |
| 9.592e-07 | -13.86 | LABBE_WNT3A_TARGETS_UP | MSigDB lists | LABBE_WNT3A_TARGETS_UP | 101 | 24 | 15632 | 1249 |
Ifit3,Cav1,Serpine1,Pdgfb,Mcm6,Ifit3b,Serpinb9,Il2rg,Dck,Actb,Nfkb2,Ccnd1,Cebpd,Gadd45g,Phgdh,Ctsc,Dusp8,Mmp14,Ccl2,Ly75,Hhex,Stxbp1,Ahr,F10 |
| 9.592e-07 | -13.86 | GO_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | MSigDB lists | GO_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | 101 | 24 | 15632 | 1249 |
Il10,Fzd5,Nr4a3,Hmox1,Tnfsf4,Tlr3,Clcf1,Bcl6,Cd40,H2-Q6,Traf2,Tnf,H2-Q4,Ifnb1,Rsad2,Il6,Nlrp3,Il4ra,Cd74,H2-Q7,Malt1,Irak3,Angpt1,Tnfrsf14 |
| 9.599e-07 | -13.86 | SIG_CD40PATHWAYMAP | MSigDB lists | SIG_CD40PATHWAYMAP | 34 | 13 | 15632 | 1249 |
Nfkbil1,Map2k4,Pik3cd,Traf5,Nfkb2,Dusp1,Nfkbia,Nfkb1,Ikbkg,Traf2,Cd40,Nfkbib,Nfkbie |
| 9.606e-07 | -13.86 | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN | 167 | 33 | 15632 | 1249 |
Slc25a37,Tpst1,Bcl6,Cd40,Tspan3,Abcb1a,Nr3c1,Ccng2,I830077J02Rik,Treml2,Mthfr,Slc30a4,Gbp3,P2ry14,Sav1,Gnb4,Ppfibp1,Lnpep,Jarid2,Sipa1l1,Myo1b,Irf8,Plscr1,Car13,Ube2e2,Dyrk2,Cd200,Ptk2,St3gal1,Map3k8,Acvr1b,Rsbn1,Dcbld2 |
| 9.679e-07 | -13.85 | protein heterodimerization activity | molecular function | GO:0046982 | 569 | 71 | 20217 | 1400 |
Ext1,Hif1a,Irak3,Gclc,Tlr2,Abtb2,Zhx2,Clcf1,Pdgfb,Tlr1,Gca,Bnip3,Ikzf1,Bcl2a1a,Irak2,Bcl2l11,Pml,H2-Aa,Tcf4,Inhba,Fzd1,H2-Q6,Fos,Taf4b,Cav1,Casp8,Daxx,Tap1,H2-Q7,H2-Q4,Katna1,Nr1h3,Mafg,Nr4a1,Max,Pdss1,Jdp2,Bmp2,Tpm4,Cflar,Pbx1,Nfkb1,Itgal,Snx2,Adora2a,Mpp7,Tap2,Foxp4,Axl,Notch1,Il12b,Ikbkg,Dr1,Atf3,Timeless,Met,Cebpd,Homer1,Mid1,Jun,Myc,Itgav,Bcl2a1b,Eno1,Eno2,Gclm,H2-Ab1,Ahr,Bcl2a1d,Tlr6,Nr3c1 |
| 9.682e-07 | -13.85 | DNA-binding transcription factor activity | molecular function | GO:0003700 | 993 | 109 | 20217 | 1400 |
Lhx2,Nfxl1,Batf,Pou2f2,Nfkb2,Hmga1,Pcgf5,Ifi207,Ifi208,Hif1a,Batf2,Stat4,Jarid2,Bcl6,Aebp2,Jdp2,Arid5b,Mafg,Mycl,Dach1,Zfp513,Ifi214,Nr4a3,Fos,Pttg1,Mxd1,Zeb1,Atf3,Egr1,Irf2,Notch1,Znfx1,Foxp4,Mndal,Klf6,Klf3,Btg2,Ifi209,Tal2,Cited2,Plagl1,Zfp281,Nr3c1,Klf8,Junb,Klf7,Egr3,Jun,Ifi213,Nfil3,Ifi204,Csrnp1,Phf6,Ets2,Tcf4,Hhex,Ifi205,Fubp1,Stat5a,Irf8,Gfi1,Hmga2,Spic,Ikzf1,Plscr1,Ifi203,Egr2,Rel,Hinfp,Zhx2,Irf4,Relb,Etv5,Spen,Ier2,Max,Nr1h3,Nr4a1,Sirt1,Tfec,Plagl2,Klf2,Prdm9,Taf4b,Etv6,Mecp2,Cebpd,Pou3f1,Ifi211,Aff1,Hdac1,Mafk,Prdm1,Irf7,Fosb,Pbx1,Nfkb1,Irf1,Hivep2,Ahr,Stat2,Stat1,Etv3,Eno1,Zbtb5,Maff,Rfx5,Myc,Stat3 |
| 9.901e-07 | -13.83 | regulation of interleukin-2 production | biological process | GO:0032663 | 58 | 16 | 20694 | 1406 |
Malt1,Prnp,Irf4,Zfp36,Pde4b,Cd34,Il1b,Cd83,Tnfsf4,Ezr,Traf2,Il1a,Tnfaip3,Ripk2,Stat5a,Nod2 |
| 9.910e-07 | -13.82 | GO_BLOOD_VESSEL_MORPHOGENESIS | MSigDB lists | GO_BLOOD_VESSEL_MORPHOGENESIS | 342 | 54 | 15632 | 1249 |
Mmp14,Edn1,Itgav,Ccl12,Syk,Flt1,Nr4a1,Tiparp,Jun,Pde3b,Col4a2,Cd34,Plau,Angpt1,Col18a1,Cx3cl1,Jag1,Sirt1,Cav1,Kdr,Tnfaip2,Itga5,Nox1,Egr3,Ptk2,Sema4a,Sat1,Acvrl1,Acvr1,Notch1,Hhex,Prdm1,Jmjd6,Calcrl,Hif1a,Nrp2,Wars,Gja1,Junb,Pik3r6,Serpine1,Pdgfrb,Fzd5,Prkx,Clic4,Thbs1,Sec24b,Vegfc,Hmox1,Zc3h12a,Ptger4,Il18,Tgfbi,Ptgs2 |
| 9.940e-07 | -13.82 | Chemokine_b/g/d | interpro domains | IPR039809 | 22 | 10 | 19984 | 1430 |
Ccl4,Cx3cl1,Ccl9,Ccl12,Ccl3,Ccl2,Ccl7,Ccl8,Ccl22,Ccl5 |
| 9.943e-07 | -13.82 | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN | 175 | 34 | 15632 | 1249 |
Rcan1,Pim1,Rcn1,Dnajb4,Ptprj,Shisa3,Dennd2a,Kif5c,Il15ra,Dnajb2,Daam1,Tnfsf14,Card6,Ccl5,Akt3,Ubash3b,Sertad3,Ppm1l,Arl4a,Prrg4,Slc28a2,Herc3,Nod1,Il15,Cutc,Ttc39c,Dync1h1,Trim36,Chst11,Sat1,Fcgr2b,Rai14,Cp,Stap1 |
| 9.984e-07 | -13.82 | positive regulation of neuron apoptotic process | biological process | GO:0043525 | 79 | 19 | 20694 | 1406 |
Casp3,Atm,Ccl3,Cdk5r1,Fas,Egr1,Tnf,Jun,Bcl2l11,Il18,Prnp,Nqo1,Nr3c1,Optn,Map2k4,Il1b,Agrn,Pmaip1,Casp2 |
| 1.000e-06 | -13.82 | NIK/NF-kappaB signaling | biological process | GO:0038061 | 28 | 11 | 20694 | 1406 |
Tnfsf15,Relb,Rel,Tlr1,Ripk3,Ikbke,Nfkb2,Irak2,Ikbkg,Malt1,Traf2 |
| 1.001e-06 | -13.81 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4_KO_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4_KO_BCELL_DN | 152 | 31 | 15632 | 1249 |
Zcchc2,Gcnt2,5430427O19Rik,Tfec,Ifi35,Herc6,Pcgf5,Cxcl10,Ifit3b,Wdfy1,Trip13,Rictor,Ube2e2,Parp12,Rgl1,Ifit3,Mov10,Clcn5,Me1,Irf2,Aim2,Ddx58,Dtx3l,Ifih1,Il4i1,Top3a,Eif2ak2,Znfx1,Cyfip1,Msr1,Mgat1 |
| 1.001e-06 | -13.81 | GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | 152 | 31 | 15632 | 1249 |
Tmem67,Sh3bgrl2,Hcls1,Irak2,Agpat4,Dio2,Gng12,Nlgn2,Ell2,Kcna3,Trib1,Trim14,Rhou,Pou2f2,P4ha1,Cd274,Vps54,Sdc4,Rgs3,Mdfic,Cyth3,Rnf135,Egr2,Rab11fip1,Phlpp1,Ap3b1,Cenpe,Nr4a1,N4bp1,Tspan3,Swap70 |
| 1.014e-06 | -13.80 | - | gene3d domains | 3.30.950.30 | 9 | 7 | 8819 | 755 |
Slfn4,Slfn2,Slfn3,Slfn8,Slfn9,Slfn5,Slfn1 |
| 1.018e-06 | -13.80 | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN | 183 | 35 | 15632 | 1249 |
Dnajb2,Cdkn1a,Snn,Fam162a,Vegfc,Kitl,Tmem123,Ust,Cxcl1,Gpd2,Serpinb9,Il12b,Trib1,Mmp9,Phlda1,Gpr132,Tap2,Cav1,Marco,Cd274,Junb,Rhoc,Etv5,Ncoa7,Tnfrsf8,Slc25a25,Cx3cl1,Icam1,Palld,Marcksl1,Taf4b,Myc,Abcb1a,Sqstm1,Flrt3 |
| 1.020e-06 | -13.80 | cellular response to oxidative stress | biological process | GO:0034599 | 204 | 34 | 20694 | 1406 |
Hdac1,Thbs1,Prdx1,Src,Lcn2,Pml,Etv5,Il6,Traf2,Hif1a,Srxn1,Jun,Sod2,Fos,Cflar,Pnpt1,Bnip3,Zc3h12a,Pdgfrb,Nqo1,Mmp9,Sirt1,Axl,Kdm6b,Vrk2,Uaca,Sphk1,Prdx5,Jak2,Tnfaip3,Slc7a11,Ripk3,Gsr,Hmox1 |
| 1.022e-06 | -13.79 | cellular chemical homeostasis | biological process | GO:0055082 | 736 | 85 | 20694 | 1406 |
Tmem178,1600014C10Rik,Ero1l,Hif1a,Mafg,Cxcl10,Lpar1,Rmdn3,Gna15,Dmxl2,Cacnb3,Mt1,Cd38,Slc39a13,Prnp,Xcr1,Lcn2,Hap1,Fpr2,Pdk3,Hk2,Slc31a1,Marcksl1,Itgav,Htr2b,Itpr1,Slc39a4,Gja1,Jak2,Cxcl3,Cav1,Prkce,Slc31a2,Hmox1,Gpr18,Hk3,Sirt1,Swap70,Grina,Slc39a14,Il1b,Atp2b4,Ptger4,Cmklr1,Kdr,Cxcl1,Cacna1d,P2ry2,Ccl3,Cx3cl1,Mt2,Slc30a1,Adrb2,Slc9a1,Slamf8,Ccl2,Rab20,Gpr35,Pml,Ccr1,Cx3cr1,Sco1,Cp,Atp13a1,Igf1r,Cd40,Clic4,Vcam1,Nox1,Edn1,Stxbp3,Ccrl2,Icam1,Hk1,Ccl5,Cxcl2,Htr2a,Bnip3,Myc,Fpr1,Ednrb,Slc4a7,Ptk2,Ptgir,Ccr3 |
| 1.031e-06 | -13.78 | GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 191 | 36 | 15632 | 1249 |
Mdfic,Angpt1,Cd34,Pim3,Cx3cl1,Nr1h3,Nlrp3,Pml,Parp10,Nfkbil1,Rsad2,Nfkbie,Rab11fip1,Rhoq,Il6,Ppp2r5a,Rhbdf2,Psmd10,Nfkbia,Tnf,Hsph1,Ezr,Il1b,Keap1,Pfkl,Dyrk2,Zc3h12a,Ptger4,Tnfsf4,Fzd1,G3bp2,Nfkbib,Il10,Pid1,Txn1,Rabgef1 |
| 1.047e-06 | -13.77 | angiogenesis | biological process | GO:0001525 | 309 | 45 | 20694 | 1406 |
Sema4a,Thbs1,Nrp2,Egr3,Ptgs2,Hif1a,Flt1,Notch1,Pik3r6,Il18,Sirt1,Zc3h12a,Cav1,Hmox1,Ahr,Itgav,Cemip2,Casp8,Nr4a1,Acvr1,Ccl12,Col4a2,Angpt1,Ccl2,Plau,Acvrl1,Jun,Cx3cl1,Pde3b,Syk,Vegfc,Kdr,Ptk2,Tnfaip2,Prkx,Pdgfrb,Fzd5,Jmjd6,Notch2,Col18a1,Calcrl,Clic4,Nox1,Wars,Edn1 |
| 1.049e-06 | -13.77 | tumor necrosis factor receptor binding | molecular function | GO:0005164 | 33 | 12 | 20217 | 1400 |
Traf2,Tnfsf4,Tnf,Traf5,Tnfsf14,Stat1,Tnfsf10,Casp8,Tnfsf9,Tnfsf15,Traf1,Tnfsf8 |
| 1.056e-06 | -13.76 | GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION | 130 | 28 | 15632 | 1249 |
Spint2,Nfkbid,Cd274,Il10,Myadm,H2-Eb1,Jak2,Il1rn,Adrb2,Irf1,Ptk2,Tnfsf4,Ifnb1,Pde5a,Peli1,Casp3,Ptpn2,Bcl6,Swap70,Ass1,Spn,Tnfrsf14,Bmp2,Il4ra,Ubash3b,Prnp,Cd74,Hlx |
| 1.056e-06 | -13.76 | cytoplasmic vesicle | cellular component | GO:0031410 | 1806 | 174 | 20747 | 1409 |
Rffl,Srgn,Acp2,Socs1,Ehd1,Ap3m2,Fchsd2,Mitd1,Fzd5,Micall2,Vcam1,Samd9l,Gbp2b,Atp11b,Sec24a,Rabgef1,Clcn5,Tlr2,Kdr,Gpr18,Carmil1,Dbnl,Sphk1,Atp11a,Whamm,Serpine1,Gbp7,Stx6,Cdc42ep4,Gpc1,Prdx5,Hck,Pla2g4a,Ap3b1,Sgk3,Rapgef2,Apba1,Lnpep,Mmp14,Spred1,Sec24b,Cd164,Mcoln2,Pmepa1,Inpp5b,Kif3c,Flt1,Tnf,Syk,Wdfy1,Acpp,Adrb2,Evl,Aoah,Plekhf2,Msr1,P2ry2,Cav1,Slc48a1,Irgm1,Fndc3a,Rab21,Edn1,Ezr,Slc30a4,Vezt,Dennd1b,Slc31a2,Rab10,Hilpda,Cd274,Tlr9,Rab9,Cdc42ep2,Stxbp1,Tlr1,Trim21,Slc39a4,Spire1,Notch1,Abcc4,Slc31a1,Tlr6,Lcn2,Gbp2,Htr2a,Itga5,Cst7,Pikfyve,Trim36,Sqstm1,Gja1,Cd74,Psd,Dennd6b,Pf4,Calcrl,Tmem67,Fas,Slc4a7,Thbs1,Pdpn,Itpr1,Il15ra,Lipg,Rab32,F11r,Sla,Stxbp3,Snx2,Cd38,Snx10,Flnb,Zyx,Ppfia3,Dst,Ociad1,Hap1,Ifitm1,Plat,Treml4,Stoml1,Arrdc4,Gbp8,Optn,Fnbp1l,Pdgfrb,Sema4c,Zc3hav1,Rap2c,Fcgr2b,Aftph,Map2k1,Il1b,Lpar1,Scyl2,Ccl2,Rubcnl,Mefv,Dtx3l,Slc29a3,Gbp9,Tmem123,Znrf1,Gbp3,H2-Eb1,Rab11fip1,Dgkh,Atm,Gch1,Chic2,Vps54,Marcksl1,Tlr3,Pde4b,Ifnar1,Fcho2,H2-Ab1,Src,Nox1,Myo1b,Ldlr,Clic4,Rab20,Esd,Sh3bp4,Stx11,Pml,Agtrap,Phlda1,Clcn7,Chmp4b,Ccr3,Dmxl2 |
| 1.062e-06 | -13.76 | mouse chr17 B1|17 17.98 cM | chromosome location | mouse chr17 B1|17 17.98 cM | 31 | 11 | 24173 | 1464 |
Tap2,Daxx,Tapbp,H2-Eb1,H2-Aa,Tap1,H2-Ab1,Brd2,Col11a2,Psmb9,Psmb8 |
| 1.067e-06 | -13.75 | negative regulation of leukocyte differentiation | biological process | GO:1902106 | 102 | 22 | 20694 | 1406 |
Bcl6,Myc,Gpr68,Pilrb1,Tmem176a,Ptpn2,Zc3h12a,Irf1,Fgl2,Cd74,Clec2d,Tnfsf4,Ubash3b,Tmem178,Trib1,Hlx,Lyn,Tmem176b,Ifnb1,Nfkbid,Il4ra,Socs1 |
| 1.076e-06 | -13.74 | MENSE_HYPOXIA_UP | MSigDB lists | MENSE_HYPOXIA_UP | 88 | 22 | 15632 | 1249 |
Klf7,Pfkfb3,Jmjd6,Gbe1,Atf3,Cebpd,Bnip3,Tiparp,P4ha2,Sod2,Fam162a,Pgk1,Nfil3,Lox,Ell2,Maff,Hk2,Ppp1r15a,Plod2,Eno2,Nampt,P4ha1 |
| 1.091e-06 | -13.73 | kinase regulator activity | molecular function | GO:0019207 | 192 | 33 | 20217 | 1400 |
Rgcc,Cdkn2d,Cdkn1a,Socs1,Ccne1,Trib3,Ccnj,Pik3r6,Daxx,Rhoh,Casp3,Spred1,Nos2,Map2k1,Cish,Kat2b,Ccng2,Socs3,Ccnd2,Wars,Socs7,Cdk5r1,Prkar2b,Spry2,Irgm2,Mtcp1,Nck1,Malt1,Ccnd1,Ccl5,Trib1,Pik3r5,Lgals9 |
| 1.106e-06 | -13.72 | WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN | MSigDB lists | WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN | 45 | 15 | 15632 | 1249 |
C3,Dusp5,Atf3,Arl4a,Rcan1,Olfml3,Ltbp2,Dusp1,Junb,Nr4a1,Klf6,Cav1,Ppp1r15a,Dusp2,Fgl2 |
| 1.106e-06 | -13.71 | epithelium development | biological process | GO:0060429 | 1038 | 111 | 20694 | 1406 |
Nr3c1,Sema3c,Src,Map2k1,Pdgfb,Vcan,Arg2,Flt1,Rilpl1,Mthfr,Lrp4,Mthfd1l,Gfi1,Notch1,Flnb,Tdrd7,Errfi1,Spint2,Foxp4,Jak2,Flrt3,Stat1,Gsta3,Inhba,Apaf1,Hdac1,Ezr,Il10,Plaur,Intu,Acvr1,Tulp3,Vegfc,Phactr4,Tnc,Socs3,Arid4a,Stat5a,Pdpn,Itga4,Myc,Fzd5,Mmp14,Clic5,Prkx,Kdm5b,Sav1,Klf2,Sema4c,Edn1,Triobp,Col18a1,Spry2,Frmd6,Csf1,Lhx2,Rapgef2,Timeless,Bmp2,Rap2c,Il6,Atm,Hif1a,Acvr1b,Vasp,Jag1,Phgdh,Ptgs2,Fam20c,Palld,Gpsm2,Hhex,Hmga2,Tagln,Casp3,F11r,Ptch1,Lmo4,Gja1,Ahr,Pbx1,Myadm,Ccnd1,Prdm1,Ift57,Met,Myd88,Angpt1,Acvrl1,Casp8,Pml,Sdc4,Cited2,Kdr,Fzd1,Jun,Il1a,Sec24b,Plod3,Rpgrip1l,Ifitm1,Slc4a7,Pou3f1,Kdm6b,Igf1r,Fndc3a,Clic4,Vcam1,Tmem67,Notch2,Icam1 |
| 1.119e-06 | -13.70 | nuclear part | cellular component | GO:0044428 | 3898 | 334 | 20747 | 1409 |
Hdac1,Etv3,Psip1,Spata13,Nr1h3,Gfi1,Atf3,Fosb,Alas1,Cdkn1a,Aff1,Casz1,Bbx,Asap3,Cutc,Sik3,Zfp281,Nr3c1,Myo10,Nfkbiz,Phf6,Tulp3,Ier2,Tpx2,Smg7,Zc3h12a,Crbn,Ubr4,Jarid2,Oas1b,Acsl5,Prpf4,Pdk3,Tra2a,Arid5a,Nmi,Tnks1bp1,Tfec,Irf7,Gsdmd,Fas,Cited2,Klf3,Taf4b,Rai14,Itpr1,Eef1e1,Rap1gap2,Higd1a,Mapkapk2,Osbpl3,Ifi207,Brd2,Klf6,Sp140,Ciapin1,Mndal,Aim2,Cebpd,Myc,Rgs3,Hspa1b,Dst,Plk3,Rnf34,Crkl,Parp3,Sbds,Ppp4r2,Mecp2,Irf4,Dnajb4,Nampt,Ifi209,Cenpj,Samhd1,Irf2,Pcgf5,Fubp1,Rapgef5,Ifi214,Jun,Irf1,Oasl2,Ankrd17,Il15,Mdn1,Zeb1,Cyth3,Etnk1,Fam111a,Klf2,Cx3cr1,Cdyl,Clic4,P4ha2,Psmb6,Noc4l,Bnip3,Ccdc86,Mafk,Junb,Bcor,Klf8,Sirt1,Syne2,Agtrap,Oas2,Kdm5b,Ptpn2,Pou2f2,Dr1,Fos,Dse,Pml,Tasor2,Rcl1,Batf,Trib3,Cnp,Wdr43,Chmp4b,Magohb,Rbl1,Tle3,Dcp2,Mpp7,Ptges,Yju2,Phlda1,Cdk5r1,Clcn7,Asf1a,Sap30,Egr2,Jak2,Znfx1,Txnrd1,Rgcc,Irf8,Phf11c,Ciita,Egr1,Ifi204,Maml2,Abtb2,Bcorl1,Dtx3l,Nxf1,Dtx2,Hsph1,Vps54,Gch1,Top3a,Atm,Rrs1,Tma16,Mtus1,Prdx1,Hspa2,Keap1,Mark2,Stap1,Phf11b,Sh3bgrl2,Ctsc,Sp100,Ikzf1,Etv5,Phf11a,Snapc1,Plekha5,Slc16a3,Tcf4,Upp1,Parp11,Nr4a1,Kdm6b,Dync1h1,Stk40,Jmjd6,Dyrk2,Itpkc,Olr1,Shfl,Rel,Hmox1,Stx6,N4bp1,Phf11d,Arid4a,Adar,Hck,Stat1,Rgs14,Timeless,Gpc1,Phlpp1,Ranbp2,Nek6,Med21,Nfkbie,Daxx,Stat5a,Pim1,Mier3,Rars,Prpf38a,Uaca,Mdm2,Tent4a,Spen,Riox2,Mcm10,Plagl1,Rilpl1,Rbpms,Aebp2,Ifi213,Mcm6,Tor3a,Birc3,Aldh1b1,Psme1,Ets2,Ednrb,Dock10,Max,Socs1,Dusp2,Trip10,Arl4a,Oas1a,Tnip1,Bcl6,Dnajb2,Smc5,Ptger4,Notch2,Slc9a1,Cacybp,Oas1g,Ahrr,Hat1,Tor1aip1,Ptk2,Malt1,Htr2b,Polr2g,Mtdh,Dusp16,Morc3,Zhx2,Nfkb1,Golga3,Carmil1,Hivep2,Anp32a,Isg20,Rabgef1,Prdm9,Dusp4,Hinfp,Trim21,Plekhg1,Actb,Casp8,Parp10,Mdfic,Psme2,Stxbp1,Tap2,Bcl9,Setdb2,Plscr1,Uchl1,Rpgrip1l,Ell2,Spire1,Gja1,Sqstm1,Hmga2,Ifi208,Serpinb9,Mppe1,Parp9,Ahr,Gbp2,Lap3,Ifi203,Oas3,Slc30a1,Tcea1,H3f3b,Pfkfb3,Ccne1,Mxd1,Sinhcaf,Ifi211,Kdm4a,Pbx1,Stat3,Etv6,Ccnd1,Ccnd2,Relb,Sertad3,Ifi205,Rsad2,Dock4,Lnpk,Slc44a1,Psma6,Rbbp8,Tut7,Ago3,Ep400,Kat2b,Smox,Hmga1,Dennd1b,Dpy19l1,Ezr,Prnp,Vezt,Hif1a,Ikbke,Mcmbp,Cdkn2d,Med13,Hspa1a,Oasl1,Hilpda,Cenpe |
| 1.125e-06 | -13.70 | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP | MSigDB lists | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP | 564 | 78 | 15632 | 1249 |
Tor3a,Eno2,Lmo4,Slc9a1,Srxn1,Procr,Alas1,Mmd,Kctd12,Endod1,Dram1,Stat1,Mafg,Adrb2,Slc25a22,Tlr2,Sh3bgrl2,Lhx2,Dnajb2,Cdkn1a,Cenpe,Nr4a1,Fam43a,Bcl2l11,Ass1,Tmem184b,Irgm2,Stard5,Rin2,Fas,Col18a1,Sdc1,Il15,Rbm43,Tuba4a,Gdf15,Higd1a,Ppp1r15a,Col11a2,Fzd5,Atp6v1d,Fosb,Btg2,Inpp5b,Pdgfb,Scn1b,Snx2,Vasn,Uba7,Dgka,Cd55,Smox,Hmox1,Slc31a1,Ak4,Grina,Il18,Ikbke,Sp110,Trafd1,Klf6,Ankrd17,Hspa1a,Phgdh,Egr2,Pnp2,Slc39a4,Carhsp1,Mdm2,Ogfrl1,Lif,Mthfr,F11r,Zfp281,Rnf135,Mapkbp1,Apaf1,Daxx |
| 1.127e-06 | -13.70 | SMALLCYTKCXC | prints domains | PR00437 | 11 | 7 | 5821 | 374 |
Cxcl11,Pf4,Cxcl1,Cxcl3,Cxcl9,Cxcl10,Cxcl2 |
| 1.133e-06 | -13.69 | plasma membrane part | cellular component | GO:0044459 | 2822 | 253 | 20747 | 1409 |
Mark2,Src,Gsr,Tlr3,Pde4b,Arf4,Fcho2,Ifnar1,H2-Ab1,Slc16a3,Gng12,Cldnd1,Cd14,Rgs1,Spn,Kctd12,Nod1,Nox1,Tnfrsf14,Prkce,H2-Eb1,Slco3a1,Jak2,Eno2,Tmem123,Marcksl1,Gng4,Eno1,Igf1r,Atp2b4,Ntng2,Hspa2,Casp3,Gng11,Stx11,Chmp4b,Ccr3,Sele,Rnf31,Mpp7,Slc2a6,Tspan3,Cyth3,Ptprj,Flrt3,Cx3cr1,Kcna3,Ldlr,Rtn2,H2-T22,Raet1e,Syne2,Dst,Itgb8,Cd38,Crkl,Ebi3,Scn1b,Il12rb1,Il6,Fcgr4,Samhd1,Plpp1,Sema4a,Fcgr1,Met,Fas,Slc4a7,Nlgn2,Thbs1,Bmp2,Pdpn,Itpr1,Mosmo,Il18rap,Csf3r,Stxbp3,Phlpp2,Sgcb,Cacnb3,Ly6a,Gramd1a,Il18,Acvrl1,Rhoh,Asah2,Il13ra1,Klrk1,Pdgfb,Ccr1,Slc39a14,Fcgr2b,Errfi1,Itgav,Axl,Plaur,Gnb4,Lpar1,Cd40,Sema4c,Homer1,Spata13,Pcdh7,Dcbld2,Adgrl2,Pdgfrb,Gna15,Slc28a2,Plek,Siglece,Traf2,Adgre4,Tmc3,Scimp,Ezr,Lcp2,Cd69,Milr1,Gpr84,Cd274,Tlr9,Itgal,Plpp3,Adora2a,Sema3c,Hspa1a,Pkp4,Acvr1,Ms4a4b,Cd82,Rims3,Hk1,Icam1,Nod2,H2-M2,Rab21,Gpr85,H2-T10,Acvr1b,P2ry2,Cav1,Itga5,Htr2a,H2-Q7,Gja1,Ddx58,Slc30a1,Calcrl,Pdzd11,H2-Q4,Tmem67,Cd74,Slamf7,Rhoc,Psd,Cp,H2-Q6,Slc39a4,Casp8,Cflar,Cpeb4,H2-T24,Stxbp1,H2-Aa,Cd86,Tlr1,Prokr1,Plscr1,Tlr6,Spire1,Sgms2,Notch1,Slc7a11,Abcc4,Htr2b,Ptk2,Fgr,P2ry12,Hvcn1,Cxcl10,Mtdh,Adam19,Itga9,Cysltr2,Nrp2,Dbnl,Icosl,Clec2d,Calhm6,Clcn5,Cd83,Gpr35,Cacna1d,Tlr2,Gpr18,Kdr,Cd34,Sdc1,Ehd1,Slc2a1,Xcr1,Antxr1,Birc2,Kcnj2,Sell,Tapbp,Slc9a1,Notch2,Fzd5,Ptgs2,Vcam1,Ccrl2,Abcc1,Slc16a1,Abcb1a,Cd200r4,Tnf,Il2rg,Flt1,Syk,Lrp8,Cxcl9,Ly75,Gem,Sipa1l1,Traf5,Lipe,H60b,Cd80,Adrb2,Olr1,Gpr132,Fscn1,Lrp4,Jag1,Rapgef2,Apba1,Cd55,Hmox1,Psd4,Rgs14,Gpc1,Lrrc8c,Hck,Flrt2,Phlpp1,Cemip2,Lnpep,Znrf3,Ptch1,Lyn,Adgrg6,Itga4 |
| 1.140e-06 | -13.68 | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_DN | MSigDB lists | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_DN | 176 | 34 | 15632 | 1249 |
Il4ra,Papss2,Atp11a,Cd180,Kmo,Tlr6,Hhex,Dnase1l3,Ifna2,Fbxo4,Cd80,Cd83,Nod1,Ifna1,Tcf4,Syk,Mid1,Ifna5,Treml2,Taf4b,Stap1,Egr2,Slc15a3,Kcnj2,Cd200,Dram1,Hmgcs1,Adam19,Myo1b,Irf8,Dusp6,Ifna6,Timeless,Phlpp2 |
| 1.143e-06 | -13.68 | REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR | MSigDB lists | REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR | 116 | 26 | 15632 | 1249 |
Nck1,Malt1,Psme1,Psmb10,Nfkbia,Nr4a1,Syk,Psmb9,Psmd10,Phlpp1,Mdm2,Nfkbie,Psma6,Psmb6,Trib3,Pik3cd,Lyn,Cdkn1a,Psmb8,Ikbkg,Rel,Akt3,Psme2,Nfkbib,Rictor,Rasgrp1 |
| 1.151e-06 | -13.67 | regulation of natural killer cell mediated cytotoxicity | biological process | GO:0042269 | 52 | 15 | 20694 | 1406 |
H60b,Lgals9,Pvr,Nectin2,Tap1,Il18rap,Rasgrp1,Clec2d,Il12b,Pik3r6,Raet1e,Klrk1,Stat5a,Tap2,Serpinb9 |
| 1.162e-06 | -13.67 | GSE14699_NAIVE_VS_ACT_CD8_TCELL_UP | MSigDB lists | GSE14699_NAIVE_VS_ACT_CD8_TCELL_UP | 184 | 35 | 15632 | 1249 |
Hopx,Psat1,Ccl5,P4ha1,Jdp2,Stx11,Hk2,Btg2,Icosl,Csf1,Plscr1,Odc1,Rcn1,Serpinb9,Ebi3,Frmd6,Osbpl3,Sh3bgrl2,Ttc39c,Tspan3,Swap70,Axl,Sbds,Rapgef5,Cst7,Phlpp1,Nfkbie,Psma6,Dusp4,Itgb8,Prnp,Arrdc4,Etv5,Rnf34,Sdc4 |
| 1.162e-06 | -13.67 | GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN | MSigDB lists | GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN | 184 | 35 | 15632 | 1249 |
Tnfrsf1b,Tuba4a,Sik3,Serpine1,Tnfsf14,Ddit4,Fzd1,Gng4,Slc31a1,Endod1,Serpinb9,Cxcl1,Cdkn1a,Pfkl,Dcbld2,Igf1r,Agrn,Slc16a3,Flt1,Dusp1,Nr4a1,Gadd45b,Tnf,Hmga1,Tcf4,Pnp2,Dusp2,Spry2,Gpr68,Mafk,Rhoh,Malt1,Isg15,Dmxl2,Pfkfb3 |
| 1.162e-06 | -13.67 | GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_DN | 184 | 35 | 15632 | 1249 |
Dusp14,Plagl2,Rras2,Prdx1,Traf1,Prnp,Atf3,Bcl2a1d,Cox17,Dusp2,Cycs,Spry2,Homer1,Bcl2a1b,Ezr,Tnf,Hivep2,Gfi1,Il1b,Serpinb2,Adam19,Fscn1,Snapc1,Cflar,Bcl2a1a,Ier3,Mthfd2,Nsmaf,Cd200,Eef1e1,Slc7a5,Gem,Hopx,Nfkb1,Eno2 |
| 1.162e-06 | -13.67 | GSE3039_CD4_TCELL_VS_B1_BCELL_DN | MSigDB lists | GSE3039_CD4_TCELL_VS_B1_BCELL_DN | 184 | 35 | 15632 | 1249 |
Csf1,Slpi,Ccdc25,Bst1,4933430I17Rik,Ccr1,Slc31a2,Cmklr1,Sh3bgrl2,Il1rn,Ccl4,Acp2,Glrx,Il1b,Hp,Ier3,Fpr1,Mefv,Clec4d,Tlr2,Ctsc,Glipr2,Rapgef5,Sod2,Csf3r,Cd302,F10,1600014C10Rik,Lpcat2,Nek6,Upp1,Cd180,Sphk1,Il4ra,Arg2 |
| 1.163e-06 | -13.66 | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN | MSigDB lists | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN | 109 | 25 | 15632 | 1249 |
Il13ra1,Tgfbi,Ms4a6d,Clec5a,Tlr2,Isg20,Btg2,Flnb,Sh3bp4,Oas2,S100a8,Irf8,Klf2,Adap2,Irf7,Sgcb,Me1,Mvp,Prnp,Sell,Fgl2,Cebpd,Gadd45b,Cst7,Bcl6 |
| 1.174e-06 | -13.66 | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 192 | 36 | 15632 | 1249 |
Ccne1,Tnfrsf1b,Pdk3,Snx10,Gem,Irf8,Flnb,Plscr1,Pdss1,Nrp2,Sap30,Hk2,Stx11,Ell2,Endod1,Casp7,Slc43a3,Osbpl3,Cdkn1a,Dio2,Ass1,H2-Q4,H2-Q6,Mtus1,Cyfip1,Dusp4,Cxcl14,Lrp8,Magohb,H2-Q7,Prdm1,Itga4,Ubash3b,Slamf7,Sgcb,Dusp14 |
| 1.181e-06 | -13.65 | p53 signaling pathway | KEGG pathways | ko04115 | 68 | 20 | 7931 | 713 |
Gadd45b,Serpine1,Ccnd2,Atm,Apaf1,Thbs1,Pmaip1,Cd82,Mdm2,Cop1,Cycs,Casp3,Sesn3,Cdkn1a,Casp8,Ccng2,Ccne1,Gadd45g,Fas,Ccnd1 |
| 1.181e-06 | -13.65 | p53 signaling pathway | KEGG pathways | mmu04115 | 68 | 20 | 7931 | 713 |
Cycs,Casp3,Cop1,Sesn3,Mdm2,Pmaip1,Cd82,Gadd45b,Serpine1,Ccnd2,Atm,Apaf1,Thbs1,Ccne1,Gadd45g,Ccnd1,Fas,Ccng2,Cdkn1a,Casp8 |
| 1.188e-06 | -13.64 | CCR chemokine receptor binding | molecular function | GO:0048020 | 45 | 14 | 20217 | 1400 |
Ccrl2,Ccl4,Ccl7,Stat3,Ccl5,Nes,Ccl22,Cx3cl1,Ccl2,Ccl12,Stat1,Ccl3,Ccl8,Ccl9 |
| 1.194e-06 | -13.64 | circulatory system process | biological process | GO:0003013 | 412 | 55 | 20694 | 1406 |
Ptk2,Gclc,Gclm,Pde5a,Plod3,Htr2a,Ednrb,Kat2b,Dock4,Icam1,Edn1,Nox1,Nampt,Gch1,Adrb2,Agtrap,Acvrl1,Met,Angpt1,Cacna1d,Sod2,Tnf,Cx3cl1,Adora2a,P2ry2,Mecp2,Vegfc,Kdr,Ccl4,Ier3,Sirt1,Il18,Cav1,Ahr,Hmox1,F11r,Stat1,Htr2b,Gja1,Kcnj2,Adora2b,Ptprj,Map2k1,Cd38,Cd34,Nr3c1,Src,Dusp5,Abr,Nos2,Ptgs2,Scn1b,Pdgfb,Ptafr,Hif1a |
| 1.223e-06 | -13.61 | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_UP | MSigDB lists | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_UP | 161 | 32 | 15632 | 1249 |
Csf3r,Mtus1,Nlrc4,Dse,P2ry12,Rapgef5,Cx3cr1,Aoah,Cp,Parp14,Dmxl2,Calcrl,Nupr1,Ddx60,Irak3,Slc28a2,Hk3,Etv5,Pdgfc,Il15,Lap3,Lcp2,Dusp6,Pou2f2,Rasgrp1,Eya4,Tlr1,Gbgt1,Igf1r,Fam20c,Cmklr1,Lrrc25 |
| 1.223e-06 | -13.61 | Cell adhesion molecules (CAMs) | KEGG pathways | mmu04514 | 166 | 35 | 7931 | 713 |
Sele,Itgal,Cd40,Itgav,Sell,Itgb8,H2-T10,Cd274,Nlgn2,Cd80,Sdc2,H2-Aa,Pvr,Cd86,H2-Q6,H2-M2,H2-Q4,Sdc4,H2-T22,Spn,Cd34,Nectin2,Vcan,Itga4,Icosl,Icam1,H2-Eb1,H2-Ab1,Vcam1,Itga9,Sdc1,F11r,H2-T24,H2-Q7,Ntng2 |
| 1.223e-06 | -13.61 | Cell adhesion molecules (CAMs) | KEGG pathways | ko04514 | 166 | 35 | 7931 | 713 |
Itgav,Cd40,Itgal,Sele,Sell,Itgb8,H2-T10,Cd274,Nlgn2,Cd80,H2-Aa,Pvr,Sdc2,H2-M2,Cd86,H2-Q6,H2-Q4,H2-T22,Sdc4,Cd34,Spn,Itga4,Nectin2,Vcan,Icosl,H2-Eb1,Icam1,H2-Ab1,Vcam1,Sdc1,Itga9,H2-T24,F11r,Ntng2,H2-Q7 |
| 1.228e-06 | -13.61 | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | 292 | 48 | 15632 | 1249 |
Btg2,Tuba4a,Nampt,Thbs1,Pcdh7,Pgk1,Rtn1,Slc31a1,Ak4,Pnp2,Fchsd2,Rnf24,D1Ertd622e,Mdm2,Abcc5,Rbbp8,Swap70,Mtus1,Traf5,Myo10,Kmo,Slpi,Med13,Fabp7,P4ha1,S100a8,Eno2,Prkar2b,Igf1r,Oasl1,Egr3,Ifi35,Hmgcs1,Tnfsf4,Asb13,Acsl1,Bnip3,Optn,Trmt1l,Ass1,Psip1,Trim36,Eif2ak2,Tspan3,Dusp14,Evl,Rtp4,Papss2 |
| 1.228e-06 | -13.61 | blood circulation | biological process | GO:0008015 | 402 | 54 | 20694 | 1406 |
Ccl4,Kdr,Vegfc,Mecp2,P2ry2,Adora2a,Cx3cl1,Tnf,Sod2,Cacna1d,Angpt1,Met,Agtrap,Acvrl1,Adrb2,Gch1,Nampt,Nox1,Edn1,Dock4,Icam1,Kat2b,Ednrb,Htr2a,Pde5a,Plod3,Gclm,Gclc,Ptk2,Hif1a,Ptafr,Pdgfb,Scn1b,Ptgs2,Nos2,Abr,Dusp5,Nr3c1,Cd34,Cd38,Map2k1,Ptprj,Adora2b,Kcnj2,Gja1,Htr2b,Stat1,F11r,Hmox1,Ahr,Cav1,Il18,Sirt1,Ier3 |
| 1.230e-06 | -13.61 | BURTON_ADIPOGENESIS_9 | MSigDB lists | BURTON_ADIPOGENESIS_9 | 82 | 21 | 15632 | 1249 |
Vcam1,Thbs1,Plat,Egr1,Pcgf5,Cyth3,Ptgs2,Cnn3,Tor1aip2,Pla2g4a,Csf1,Phlda1,Stxbp3,Cebpd,Cnn2,Csrp1,Ccl12,Plk2,Fos,Gem,Cited2 |
| 1.234e-06 | -13.61 | RYTTCCTG_ETS2_B | MSigDB lists | RYTTCCTG_ETS2_B | 991 | 121 | 15632 | 1249 |
Aff1,Extl2,Nck1,Evl,Rin2,S1pr2,Mllt6,Mid1,Dusp4,Fcgr2b,Gpr18,Cited2,Trip10,Hmga1,Cnn2,Lhx2,Cdkn1a,Arf4,Rap2c,Trib1,Lyn,Sema4c,Egr3,Dgkh,Mmp9,Ptgir,Il18rap,Etv6,Psme2,Atxn7l1,Slpi,Lmo4,Casp8,Nfkb1,Etv5,Rgs3,Tsku,Tab2,Prdm1,Csrnp1,Sele,Treml2,Nfkbie,Csf3r,Bcl6,Pcdh7,Gcnt2,Ralgds,Nr4a3,Sh3bp4,Vasp,Tmeff1,Rab10,Ddit4,Gpr132,Pdgfrb,Cdyl,Ccr1,Atp2b4,Rbms2,Gng11,Abr,Egr1,Mapkapk2,Cox17,Cyfip1,Dock4,Cx3cr1,Flt1,Hivep2,Ccl12,Gfi1,Actb,Hcls1,Mefv,Pik3cd,Etnk1,Tnfsf4,Dck,Tmod3,Stat4,Flnb,Marco,Itgal,Il10,Layn,Rnf31,Myo10,Bmp2,Calcrl,Cd180,Fgr,Slc30a4,Hhex,Lif,Rhoh,Zfp800,Timp1,Rgs14,Itpr1,Cd40,Parp8,Hcar2,Zhx2,Tfec,Osbpl3,Il1rn,Cmklr1,Acsl5,Chic2,Dnaja2,Nfkbid,Stx11,Dgka,Pdgfb,Cd86,4930523C07Rik,Junb,Map4k4,Card6,Sesn3 |
| 1.240e-06 | -13.60 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B | 490 | 70 | 15632 | 1249 |
Gpr85,Ptgs2,Traf3ip2,Il15ra,Plaur,Serpinb2,Inpp1,Nfkb2,Fosb,Serpine1,Cd274,Tap2,Myadm,Dusp6,Slc31a2,Vasn,Inhba,Eya4,Antxr1,Scn1b,Nmi,Btg2,Arg2,Lif,Plk3,Mvp,Apaf1,Myd88,Dusp1,Klf6,Dync1h1,Mafk,Tnfsf8,Cish,Rab21,Sat1,Sema4a,Adrb2,Itpkc,Dram1,Etnk1,Pmepa1,Frmd6,Igf1r,Lcn2,Itgal,Mfap3l,Casp2,Ccrl2,Srxn1,Bcl9,Cdkn2d,Nfkbiz,Fas,Dusp14,Olr1,Fbxo4,Slc48a1,Gng11,Rras2,Col4a2,Sqstm1,Agrn,Nr4a1,Gadd45g,Nqo1,Mmp14,Rai14,Il6,Ggct |
| 1.243e-06 | -13.60 | positive regulation of interleukin-1 secretion | biological process | GO:0050716 | 34 | 12 | 20694 | 1406 |
Ifnar1,Tlr2,Ccl3,Hk1,Aim2,Nod2,Ripk2,Gsdmd,Fzd5,Casp4,Nlrp3,Casp1 |
| 1.245e-06 | -13.60 | T cell differentiation | biological process | GO:0030217 | 161 | 29 | 20694 | 1406 |
Syk,Ptger4,Il6,Rsad2,Stat5a,Bcl2a1d,Stat3,Batf,Irf1,Ikzf1,Spn,Tnfsf8,Sema4a,Ripk3,Fas,Il15,Clec4d,Gpr18,Egr1,Clec4e,Relb,Jmjd6,Fzd5,Irf4,Ptpn2,Gadd45g,Il12b,Rhoh,Cd74 |
| 1.258e-06 | -13.59 | intracellular vesicle | cellular component | GO:0097708 | 1811 | 174 | 20747 | 1409 |
Ldlr,Clic4,Rab20,Sh3bp4,Esd,Stx11,Pml,Agtrap,Phlda1,Clcn7,Chmp4b,Ccr3,Dmxl2,Mefv,Dtx3l,Gbp9,Slc29a3,Tmem123,Gbp3,Znrf1,H2-Eb1,Rab11fip1,Dgkh,Atm,Chic2,Gch1,Vps54,Marcksl1,Tlr3,Pde4b,Fcho2,Ifnar1,H2-Ab1,Src,Nox1,Myo1b,Optn,Fnbp1l,Pdgfrb,Sema4c,Zc3hav1,Rap2c,Aftph,Map2k1,Fcgr2b,Il1b,Lpar1,Scyl2,Rubcnl,Ccl2,Fas,Slc4a7,Thbs1,Itpr1,Pdpn,Il15ra,Lipg,Rab32,F11r,Sla,Stxbp3,Cd38,Snx2,Flnb,Snx10,Zyx,Ppfia3,Dst,Ociad1,Hap1,Ifitm1,Plat,Treml4,Stoml1,Gbp8,Arrdc4,Cdc42ep2,Rab9,Stxbp1,Tlr1,Trim21,Slc39a4,Spire1,Notch1,Abcc4,Slc31a1,Tlr6,Gbp2,Lcn2,Itga5,Cst7,Htr2a,Pikfyve,Trim36,Sqstm1,Gja1,Cd74,Dennd6b,Psd,Calcrl,Pf4,Tmem67,Aoah,Plekhf2,Msr1,P2ry2,Slc48a1,Cav1,Fndc3a,Irgm1,Rab21,Edn1,Ezr,Vezt,Slc30a4,Dennd1b,Slc31a2,Hilpda,Rab10,Tlr9,Cd274,Stx6,Gbp7,Cdc42ep4,Gpc1,Prdx5,Hck,Pla2g4a,Sgk3,Ap3b1,Apba1,Rapgef2,Mmp14,Lnpep,Spred1,Sec24b,Cd164,Pmepa1,Mcoln2,Inpp5b,Kif3c,Tnf,Flt1,Syk,Wdfy1,Acpp,Adrb2,Evl,Rffl,Srgn,Acp2,Socs1,Ehd1,Ap3m2,Fchsd2,Micall2,Mitd1,Fzd5,Vcam1,Samd9l,Gbp2b,Sec24a,Atp11b,Clcn5,Rabgef1,Tlr2,Gpr18,Kdr,Sphk1,Dbnl,Carmil1,Atp11a,Serpine1,Whamm |
| 1.266e-06 | -13.58 | GO_INACTIVATION_OF_MAPK_ACTIVITY | MSigDB lists | GO_INACTIVATION_OF_MAPK_ACTIVITY | 25 | 11 | 15632 | 1249 |
Dusp5,Rgs3,Dusp16,Spred1,Dusp14,Dusp1,Dusp6,Cav1,Dusp8,Dusp2,Dusp4 |
| 1.270e-06 | -13.58 | GSE20727_CTRL_VS_H2O2_TREATED_DC_UP | MSigDB lists | GSE20727_CTRL_VS_H2O2_TREATED_DC_UP | 169 | 33 | 15632 | 1249 |
Rbms1,Actb,Max,Rcsd1,Ifi204,Flnb,Ifi208,Ifi211,Ifi203,Sik3,Mndal,Plekhg1,Zc3hav1,Hck,Ifi207,St3gal3,Cdk5r1,Il4ra,Ifi214,Irs2,Rab11fip1,Fchsd2,Bbx,Ifi44,Parp14,Plekhf2,Dhrs9,Ifi213,Crbn,Stat5a,Ifi205,Ifi209,Homer1 |
| 1.270e-06 | -13.58 | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 169 | 33 | 15632 | 1249 |
Ets2,Eno1,Tnf,Il18bp,Tra2a,Psma6,Irgq,Bnip3,Icam1,Il1a,Etv3,Traf1,Nlrp3,Sertad3,Plk3,Csrnp1,Tpi1,F10,Ppp1r15a,Abtb2,P4ha1,Hk2,Ddit4,Pdgfb,Slc7a5,Arl5b,Ptgs2,Egr3,Scyl2,Ldha,Fam162a,Pgk1,Sec24a |
| 1.270e-06 | -13.58 | adenyl ribonucleotide binding | molecular function | GO:0032559 | 1448 | 147 | 20217 | 1400 |
Acsl5,Pdgfrb,Mov10,Mapkapk2,Fam20c,Slfn8,Prkx,Ripk3,Igf1r,P2ry2,Syk,Mcm6,Gk,Src,Ifih1,Eif2ak2,Hspa2,Acvr1b,Kif9,Mark2,Kif3c,Pim2,Sgk3,Swap70,Mcm9,Dhx58,Pik3cd,Hsph1,Tap2,Hck,Atm,Acsl1,Tent2,Fgr,Pgs1,Hk1,Axl,Dync1h1,Dck,Asns,Jak2,Met,Map2k4,Rars,Actb,Srxn1,Sik3,Dnaja2,Ep400,Atp13a1,Plk2,Pde4b,Nlrc5,Dgka,Katna1,Nod2,Trip13,Chd9,Oasl1,Ddx4,Abcb1a,Prkce,Lyn,Ube2e2,Abcc1,Atp11a,Ptk2,Grk3,Dyrk2,Gclc,Trib1,Apaf1,Wars,Pim3,Atp2b4,Tent4a,Ksr1,Oas3,Itpkc,Cenpe,Cmpk2,Pikfyve,Smc5,Prag1,Stk40,Plk3,Slfn5,Flt1,Pgk1,Nlrc4,Myo1b,Acvrl1,Pdk3,Pfkl,Map4k4,Nlrp3,Ikbke,Ddx58,Sphk1,Pim1,Map3k6,Hk2,Map3k8,Tor3a,Mlkl,Dnaja1,Nek6,Pcx,Ube2f,Papss2,Slfn9,Hspa1a,Hk3,Map2k1,Clcn5,Etnk1,Ripk2,Cgas,Myo10,Clcn7,Vrk2,Trib3,Tap1,Ass1,Kdr,Helz2,Tyk2,Atp10a,Oas2,Nod1,Acvr1,Mthfd1l,Abcc5,Oasl2,Ak4,Irak3,Scyl2,Akt3,Ube2e1,Tlk2,Prkar2b,Hspa1b,Ascc3,Ciita,Ube2l6,Ehd1,Irak2 |
| 1.275e-06 | -13.57 | heart development | biological process | GO:0007507 | 573 | 70 | 20694 | 1406 |
Edn1,Vcam1,Tmem67,Notch2,Adap2,Calcrl,Jmjd6,Flrt2,Pdgfrb,Pdlim7,Rpgrip1l,Itga4,Sec24b,Sav1,Kdm6b,Casp7,Mmp13,Kdr,Cacybp,Cited2,Pdpn,Hopx,Jun,Sod2,Fzd1,Adam19,Adgrg6,Acvrl1,Angpt1,Met,Slc9a1,Ift57,Prdm1,Gys1,Acvr1,Map2k4,Cdkn1a,Casp8,Ptch1,Lmo4,Htr2b,Bcor,Gja1,Dnaaf3,Flrt3,Casp3,Foxp4,Crkl,Ahr,Tnfrsf1b,Mmp9,Mdm2,Sgcb,Hhex,Notch1,Prokr1,Hif1a,Vcan,Atm,Spred1,Pdgfb,Tab2,Lox,Jag1,Nrp2,Thbs1,Sema3c,Ptprj,Bmp2,Map2k1 |
| 1.276e-06 | -13.57 | activation of protein kinase activity | biological process | GO:0032147 | 272 | 41 | 20694 | 1406 |
Traf2,Pdgfb,Nek6,Syk,Tpx2,Eif2ak2,Daxx,Mdfic,Mapkbp1,Tnf,Tnfsf15,Mul1,Ripk2,Lpar1,Map3k8,Src,Met,Angpt1,Prnp,Map4k4,Thbs1,Map2k4,Map2k1,Bmp2,Ikbkg,Jak2,Crkl,Map3k6,Rgcc,Ripk3,Il18,Malt1,Pdgfc,Gdf15,Gadd45g,Mlkl,Irak2,Gadd45b,Tlr1,Il1b,Cd74 |
| 1.288e-06 | -13.56 | LIU_TARGETS_OF_VMYB_VS_CMYB_DN | MSigDB lists | LIU_TARGETS_OF_VMYB_VS_CMYB_DN | 40 | 14 | 15632 | 1249 |
Col4a2,Ptprj,Usp31,Mapkapk2,Palld,Kcna3,Clec5a,Adrb2,Il12b,Il6,Vcan,Cers6,Ehd1,Gpr18 |
| 1.294e-06 | -13.56 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | 672 | 89 | 15632 | 1249 |
Ust,Chd9,Znrf1,Hsd17b7,Dnajb2,H3f3b,Cpeb4,Slpi,Kctd12,Syne2,Ednrb,Sik3,Pid1,Phf11a,Kif9,Col4a2,Spred1,Kat2b,Mllt6,Rapgef5,Gadd45b,Cited2,Plat,Ppp2r2a,St3gal1,Cdc42ep4,Psd4,Csrp1,Gja1,Fzd5,Lipg,Zfp319,Tnfaip3,Csrnp1,Asap3,Lrch3,Rnf135,Pigv,F11r,Tab2,Cd74,Itgb8,Glipr2,Rbpms,Phf11b,Klf6,Cd302,Tcf4,Arhgef3,Hcls1,Cflar,Rnaset2b,Ell2,Phf11d,Flnb,Ksr1,Ltbp2,Phf11c,Lrp8,Dtwd1,Ccnd2,Trim13,Peli1,Bbx,Tmem171,Tra2a,Sdc2,Tagln,Bcl2l11,Hivep2,Nfkbia,Jun,Thbs1,Rsbn1,Ptger4,Tapbpl,Mob3b,Rilpl1,Tshz1,Nampt,Rnaset2a,Smg7,Hhex,Slco3a1,Spata13,Rffl,Tbc1d1,Parp8,Itpr1 |
| 1.304e-06 | -13.55 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_UP | 177 | 34 | 15632 | 1249 |
Nupr1,Irs2,Cd74,Bfar,Ciita,Dnase1l3,Cd164,Ezr,Tank,Rbbp8,Serp1,Cd40,Stap1,Fchsd2,Stk40,Dtnb,Mafk,Errfi1,Ifrd1,Fgl2,Cdyl2,Optn,Ripk2,Cpeb4,Cxcl10,Azi2,Map3k8,Osgin2,Cd82,Whamm,Birc3,Sco1,AA467197,Ccrl2 |
| 1.304e-06 | -13.55 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP | 177 | 34 | 15632 | 1249 |
Crlf3,Cd83,Il15,Fbrsl1,Cdc42ep2,Crim1,Etv5,Gbp2,Hck,Relb,Evl,Rab19,Dcp2,Usp18,Calcrl,Isg15,Dtx3l,Irgm2,Rnf114,Agrn,Rgs1,Ppfibp2,Tagap,Il1b,Tcea1,Etnk1,Spire1,Procr,Isg20,Akt3,Psme2,Ube2e2,Itgal,Cd86 |
| 1.305e-06 | -13.55 | Death Receptor Signalling | REACTOME pathways | R-MMU-73887 | 42 | 15 | 8608 | 757 |
Ikbkg,Casp8,Birc3,Fas,Cflar,Traf2,Rnf31,Traf1,Tab2,Birc2,Tnfsf10,Tax1bp1,Tnf,Nsmaf,Tnfaip3 |
| 1.323e-06 | -13.54 | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | REACTOME pathways | R-MMU-198933 | 114 | 27 | 8608 | 757 |
C3,Ifitm1,Cd40,H2-T10,H2-Q7,Cd300e,Sell,H2-Q4,Treml2,H2-M2,Klrk1,H2-Q6,Itga4,H2-T24,Slamf7,Itgal,Cd300lf,Nectin2,Trem1,Cd200,H2-T22,Vcam1,Treml4,Clec2d,Icam1,Cd34,Cd200r4 |
| 1.325e-06 | -13.53 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP | 185 | 35 | 15632 | 1249 |
Cdk5r1,Sphk1,Sgms2,Prrg4,Mcoln2,Fas,Sla,Slc25a25,Tiparp,Hspa1a,Rhbdf2,Zswim4,Sbds,Nr4a1,Tnf,Slc15a3,Tmem171,Map3k8,Zc3h12a,Shisa3,Plaur,Cflar,Clcf1,Jak2,Rsbn1,Il10,Asns,Cdyl,Slc13a3,Ppp2r3a,Mmp13,Atxn7l1,Scn1b,Zeb1,Ksr1 |
| 1.325e-06 | -13.53 | GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 185 | 35 | 15632 | 1249 |
Tle3,Pfkfb3,Fcgr1,P2ry14,Isg15,Nlrp3,Slco3a1,Mxd1,Plk3,H2-Q7,Tlr6,Peli1,H2-Q6,Acpp,Rhbdf2,Zyx,Dock4,Bcl6,Rab32,H2-Q4,Zcchc2,Rap2c,Mppe1,Irf1,Frmd4a,Map2k4,Mafg,Xkr8,Fam53c,Ext1,Pstpip2,Plscr1,Ppp1r15a,Osm,Junb |
| 1.325e-06 | -13.53 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_UP | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_UP | 185 | 35 | 15632 | 1249 |
Clec4d,Ptgir,Herc6,Cdkn1a,Il15ra,Rgs1,Ppp2r1b,Irak2,Hopx,Plek,Ankib1,Slc7a8,Oas2,Inhba,Slc7a5,Trim26,Ifih1,Tmtc2,Mcoln2,Mxd1,Tsku,Slfn5,Slamf7,Rbms2,Rras2,P2ry12,Lrp4,Ifit2,Parp9,Vcan,Treml2,Mmp14,Phgdh,Pla2g4a,Ctsc |
| 1.325e-06 | -13.53 | GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN | 185 | 35 | 15632 | 1249 |
Psmb6,Filip1l,Cd200,Ier3,Mthfd2,Mcm6,Rcan1,Ldlr,Cflar,Plaur,Stip1,P4ha1,Dusp6,Tor3a,Nampt,Pdk3,Lap3,Phlda1,Pdss1,Timeless,Slc7a5,Wars,Tpi1,Psmb10,Sla,Sdc4,Hk3,Slc16a3,Apobec3,Dnaja1,Eno1,Rab11fip1,Ggct,Irf4,Dusp4 |
| 1.359e-06 | -13.51 | GO_CELLULAR_RESPONSE_TO_STARVATION | MSigDB lists | GO_CELLULAR_RESPONSE_TO_STARVATION | 117 | 26 | 15632 | 1249 |
Slc39a4,Ifi213,Eif2ak2,Ifi209,Ifi205,Slc2a1,Jun,Ifi207,Atf3,Upp1,Ifi214,Sphk1,Wdr59,Ifi211,Ifi208,Sirt1,Ifi203,Cav1,Asns,Ppp1r15a,Mndal,Cdkn1a,Cpeb4,Max,Zc3h12a,Ifi204 |
| 1.360e-06 | -13.51 | transcription regulatory region DNA binding | molecular function | GO:0044212 | 977 | 107 | 20217 | 1400 |
Nr4a3,Ifi214,Mycl,Zfp513,Dach1,Zeb1,Mxd1,Fos,Jdp2,Arid5b,Bcl6,H3f3b,Jarid2,Aebp2,Mafg,Ifi207,Pcgf5,Hmga1,Stat4,Hif1a,Batf2,Ifi208,Lhx2,Nfxl1,Ciita,Nfkb2,Tiparp,Pou2f2,Batf,Ets2,Ifi213,Ifi204,Nfil3,Rbl1,Jun,Junb,Klf8,Nr3c1,Klf7,Egr3,Klf3,Arid5a,Klf6,Mndal,Plagl1,Zfp281,Tal2,Ifi209,Atf3,Dr1,Egr1,Kat2b,Foxp4,Notch1,Irf2,Sp140,Bcor,Tfec,Prdx5,Etv6,Prdm9,Max,Ier2,Sirt1,Nlrc5,Nr4a1,Nr1h3,Egr2,Rel,Ifi203,Etv5,Irf4,Relb,Hinfp,Tcf4,Hhex,Ifi205,Spic,Ikzf1,Gfi1,Irf8,Stat5a,Zbtb5,Eno1,Stat1,Etv3,Tnf,Kdm6b,Stat3,Maff,Myc,Rfx5,Ahr,Hivep2,Irf1,Stat2,Prdm1,Irf7,Mafk,Lmo4,Arid4a,Nfkb1,Pbx1,Fosb,Ifi211,Cebpd,Hdac1 |
| 1.363e-06 | -13.51 | MODULE_92 | MSigDB lists | MODULE_92 | 139 | 29 | 15632 | 1249 |
Tnfsf10,Ccl4,Il1b,Ptgir,Cxcl10,Acsl1,Il18,Csf3,Inhba,Adora2a,Ccr1,Nampt,Ltbp2,Gja1,Osm,Il15,Bmp2,Lif,Il1a,Ccl22,Cx3cl1,Isg15,Edn1,Il6,Ccl2,Cxcl14,Nqo1,Ccl12,Zyx |
| 1.365e-06 | -13.50 | Chemokine signaling pathway | WikiPathways | WP2292 | 184 | 43 | 4813 | 540 |
Ccl2,Cxcl10,Nfkbib,Crkl,Gnb4,Pf4,Ccr1,Lyn,Gng11,Ccl7,Cxcl2,Map2k1,Cxcl9,Nfkbia,Stat1,Ptk2,Gng4,Gng12,Prkx,Ccl4,Ccl8,Fgr,Stat3,Ccl22,Ccr3,Stat2,Pik3cd,Ikbkg,Ccl9,Ccl12,Akt3,Cxcl11,Ccl5,Jak2,Xcr1,Nfkb1,Ccl3,Cx3cr1,Cx3cl1,Cxcl14,Hck,Cxcl1,Pik3r5 |
| 1.379e-06 | -13.49 | AMUNDSON_GENOTOXIC_SIGNATURE | MSigDB lists | AMUNDSON_GENOTOXIC_SIGNATURE | 96 | 23 | 15632 | 1249 |
Gem,Tor1aip1,Lcp2,Pdlim7,Ppp4r2,Phlda1,Slc9a1,Hk2,Dusp5,Nr4a3,Gfpt1,Gfi1,Sec24b,Tnf,Axl,Fos,Myc,Spry2,Nek6,Egr1,Irf2,Ier2,Itga4 |
| 1.380e-06 | -13.49 | GO_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | 76 | 20 | 15632 | 1249 |
Cd80,Clcf1,Il1b,C3,Ripk2,Malt1,H2-Q7,Tnfsf4,Hlx,Il12b,Nlrp3,Rsad2,Sirt1,Il12rb1,H2-Q4,Tnf,Cd40,H2-Q6,Fzd5,Traf2 |
| 1.404e-06 | -13.48 | MyD88-independent TLR3/TLR4 cascade | REACTOME pathways | R-MMU-166166 | 76 | 21 | 8608 | 757 |
Nod2,Irf7,Ikbkg,Ripk2,Map2k4,Nfkb1,Fos,Cd14,Tab2,Myd88,Nfkbia,Mapkapk2,Irak2,Map3k8,Nod1,Nfkb2,Ppp2r1b,Nfkbib,Dusp4,Dusp6,Jun |
| 1.404e-06 | -13.48 | Toll Like Receptor 3 (TLR3) Cascade | REACTOME pathways | R-MMU-168164 | 76 | 21 | 8608 | 757 |
Jun,Dusp6,Dusp4,Nfkbib,Ppp2r1b,Nfkb2,Map3k8,Nod1,Irak2,Mapkapk2,Nfkbia,Myd88,Tab2,Cd14,Fos,Nfkb1,Ripk2,Map2k4,Ikbkg,Nod2,Irf7 |
| 1.409e-06 | -13.47 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN | 162 | 32 | 15632 | 1249 |
Dock10,Ccnd1,Errfi1,Chst11,Fgl2,Dennd1b,Nat2,Minpp1,Irgq,Itpr1,Fos,Txnrd1,Me1,Ubash3b,Stxbp1,Malt1,Hhex,Prdm1,Hat1,Serpine1,Trem1,Tagap,Rgs1,Hcls1,Kitl,Il18,Clec5a,Lpar1,Filip1l,Il13ra1,Oasl1,Cpeb4 |
| 1.416e-06 | -13.47 | DORN_ADENOVIRUS_INFECTION_32HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_32HR_DN | 35 | 13 | 15632 | 1249 |
Egr3,Ell2,Ier3,Cd83,Rnd3,Nfkb2,Nfkbia,Nr4a1,Junb,Txnrd1,Plk2,Fubp1,Ccnd1 |
| 1.427e-06 | -13.46 | STAT5A_01 | MSigDB lists | STAT5A_01 | 226 | 40 | 15632 | 1249 |
Csf3,Ccdc25,Maff,Dgka,Slc9a1,Plscr1,Osm,Ccl5,Map4k4,Prkar2b,Nfil3,Cacna1d,Irf1,Nr4a3,Tmod3,Dtx2,Itpkc,Psd,Mecp2,Irf4,Cish,Fos,Bcl6,Zyx,Flt1,Abcc5,Ccl12,Etv5,Olfml3,Batf,Icam1,Sdc1,Plagl1,Gmppb,Prdm1,Irf2,Usp25,Lif,Palld,Apba1 |
| 1.430e-06 | -13.46 | PID_CD40_PATHWAY | MSigDB lists | PID_CD40_PATHWAY | 30 | 12 | 15632 | 1249 |
Myc,Nfkb1,Nfkbia,Birc3,Stat5a,Jun,Birc2,Cd40,Traf2,Tnfaip3,Traf1,Map2k4 |
| 1.431e-06 | -13.46 | GO_POSITIVE_REGULATION_OF_SECRETION | MSigDB lists | GO_POSITIVE_REGULATION_OF_SECRETION | 346 | 54 | 15632 | 1249 |
Ptafr,Clec5a,Adora2b,Ptger4,Htr2b,Il1b,Hcar2,Vegfc,Sec24a,Cd274,Gja1,H2-Eb1,Mmp13,Inhba,Fgr,Sphk1,Hif1a,Il1a,Lif,Aim2,Cd38,Cd14,Serp1,Ifnar1,Casp1,Src,Tnf,Gpr68,Rab9,Tnfsf4,Nlgn2,Jak2,P2ry2,Il10,Ednrb,S100a8,Clec4n,Rasgrp1,Irs2,Il4ra,Nlrp3,Sdc1,Stxbp1,Tnfrsf14,Clec4e,Cd34,Sdc4,Syk,Ezr,Gsdmd,Nod2,Prkce,Il6,Edn1 |
| 1.436e-06 | -13.45 | MULLIGHAN_MLL_SIGNATURE_2_DN | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_2_DN | 251 | 43 | 15632 | 1249 |
Ifi208,Icosl,Wdr59,Hsd17b12,Sipa1l1,Ralgds,Clic4,Cxcl1,Abcc4,Ifi44,D1Ertd622e,Kdm5b,Rbpms,Ifi213,Src,Stat5a,Ifi205,Serp1,Ifi209,Rhoh,Ube2e1,Ier2,Hif1a,Ifi211,Ifi203,Stat4,Mndal,Fscn1,Cd200,Ptgir,Egr3,Endod1,Ifi204,Stap1,Abcb1a,Itgav,Agrn,Ass1,Eif2ak2,Cd34,Dusp14,Ifi207,Ifi214 |
| 1.438e-06 | -13.45 | cellular cation homeostasis | biological process | GO:0030003 | 630 | 75 | 20694 | 1406 |
Rab20,Gpr35,Ccl2,Slc9a1,Slamf8,Slc30a1,Adrb2,Sco1,Cp,Cx3cr1,Pml,Ccr1,Cmklr1,Kdr,Atp2b4,Ptger4,Cx3cl1,Mt2,P2ry2,Ccl3,Cacna1d,Cxcl1,Ednrb,Slc4a7,Fpr1,Bnip3,Myc,Htr2a,Ccr3,Ptgir,Nox1,Ccrl2,Edn1,Clic4,Atp13a1,Cd40,Ccl5,Cxcl2,Prnp,Cd38,Mt1,Slc39a13,Cacnb3,Dmxl2,Lcn2,Fpr2,Hap1,Xcr1,Cxcl10,Mafg,Hif1a,Ero1l,Tmem178,1600014C10Rik,Gna15,Lpar1,Rmdn3,Swap70,Il1b,Slc39a14,Grina,Slc39a4,Htr2b,Itgav,Itpr1,Gja1,Jak2,Marcksl1,Slc31a1,Gpr18,Hmox1,Slc31a2,Prkce,Cav1,Cxcl3 |
| 1.438e-06 | -13.45 | ISG15-protein conjugation | biological process | GO:0032020 | 5 | 5 | 20694 | 1406 |
Ube2l6,Ube2e2,Ube2e1,Uba7,Isg15 |
| 1.438e-06 | -13.45 | negative regulation of vasculature development | biological process | GO:1901343 | 128 | 25 | 20694 | 1406 |
Notch1,Hhex,Klf2,Stat1,Pgk1,Serpine1,Spry2,Rgcc,Pf4,Adrb2,Thbs1,Plk2,Ccl2,Col4a2,Pml,Sema4a,Cx3cr1,Pde3b,Spred1,Lif,Pdgfb,Ptger4,Mecp2,Cxcl10,Tcf4 |
| 1.453e-06 | -13.44 | GO_MAP_KINASE_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_MAP_KINASE_PHOSPHATASE_ACTIVITY | 13 | 8 | 15632 | 1249 |
Dusp1,Dusp5,Dusp6,Dusp16,Dusp4,Dusp14,Dusp8,Dusp2 |
| 1.458e-06 | -13.44 | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP | 170 | 33 | 15632 | 1249 |
Nfkb1,Daam1,Rel,Rnaset2a,Inpp5b,Dgka,Dck,Traf3ip2,Cd200,Pik3cd,Mppe1,Zcchc2,Bcl2a1a,Notch2,Dek,Snn,Rnaset2b,Bcl2a1b,Plekhf2,Bcl6,Slc15a3,Rab11fip1,Bcl2a1d,Hhex,Evl,Abr,Il4ra,Pikfyve,Socs1,Cd74,Trim13,Sav1,Cd83 |
| 1.458e-06 | -13.44 | GO_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS | 132 | 28 | 15632 | 1249 |
Ptgs2,Lpar1,Adrb2,Nox1,Cpeb4,Hmox1,Fam162a,Cav1,Ppp1r15a,Pdk3,Vasn,Sirt1,Egln3,Slc9a1,Hif1a,Icam1,Plk3,Fas,Egr1,Notch1,Daxx,Plau,Cited2,Src,Mdm2,Edn1,Bnip3,Prkce |
| 1.468e-06 | -13.43 | GSE3565_DUSP1_VS_WT_SPLENOCYTES_UP | MSigDB lists | GSE3565_DUSP1_VS_WT_SPLENOCYTES_UP | 147 | 30 | 15632 | 1249 |
Mmp25,Ttc39b,Ptprj,Kif5c,Ell2,Nfil3,Cmklr1,Osbpl3,Rgs1,Ccl4,Itgal,Hopx,Gna15,Snx10,Myadm,Ccl5,Tnfrsf1b,Smpdl3b,Il18rap,Zc3h7a,Itga4,Prdm1,Atp2b4,Ttc39c,Cyfip1,Rhbdf2,Cx3cr1,Fgl2,Mlkl,Fcgr2b |
| 1.487e-06 | -13.42 | regulation of actin cytoskeleton organization | biological process | GO:0032956 | 343 | 48 | 20694 | 1406 |
Vasp,Lpar1,Tmod3,Cyfip1,Hcls1,Hck,Csf3,Plek,Cdc42ep2,Whamm,Rictor,Tlr2,Spire1,Prkce,Cdk5r1,Rnd3,Myadm,Dbnl,Rhof,Asap3,F11r,Rhoh,Swap70,Fchsd2,Il1a,Cx3cl1,Rhou,Ptger4,Bst1,Sdc4,Evl,Nck1,Cdc42ep4,Met,Carmil1,Tmsb10,Notch2,Icam1,Rgcc,Fgr,Rhoq,Edn1,Stap1,Rnd1,Rhoc,Rac3,Fscn1,Pdgfrb |
| 1.489e-06 | -13.42 | negative regulation of interleukin-12 production | biological process | GO:0032695 | 19 | 9 | 20694 | 1406 |
Irak3,Thbs1,Acp5,Cmklr1,Nfkb1,Il10,Nod2,Tlr2,Mefv |
| 1.489e-06 | -13.42 | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | 210 | 38 | 15632 | 1249 |
Dgkh,Mob3b,Ifi204,Chd9,Col27a1,Cflar,Abcc4,Frmd6,Mob3c,Igf1r,Rnf31,Casp4,Mndal,Lad1,Atxn7l1,Ifi208,Ext1,Ifi211,Dgka,Ifi203,Jag1,Pml,Ifi214,Lpcat2,Rnd3,Notch1,Ifi207,Casp1,Abcc5,Ifi213,Cnn2,Ifi205,Ifi209,Myc,Spry2,Prdx5,Ccnd1,Fgl2 |
| 1.491e-06 | -13.42 | GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_UP | MSigDB lists | GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_UP | 178 | 34 | 15632 | 1249 |
Bcl6,Cited2,Fos,Znfx1,Homer1,Bcl2a1b,Dync1h1,Nr4a1,Dusp1,Bcl2a1d,Ccng2,Ifrd1,Vcan,Dusp2,Kcnj2,Nr1h3,Fpr2,Il1a,Egr1,Atf3,Mov10,Tnfrsf1b,Cxcl2,Spint2,Ccrl2,Phlda1,Azi2,Adrb2,Mcm6,Mmp9,Hsd17b7,Asf1a,Bcl2a1a,Notch2 |
| 1.491e-06 | -13.42 | GSE557_CIITA_KO_VS_I_AB_KO_DC_UP | MSigDB lists | GSE557_CIITA_KO_VS_I_AB_KO_DC_UP | 178 | 34 | 15632 | 1249 |
Batf,Tle3,Clcn5,Gbp3,Etv3,Cish,D1Ertd622e,Samd9l,Mllt6,Fgl2,Bcl2l11,Agrn,Ifnar1,Cd40,Dse,Cd82,Slfn3,Pmepa1,Dnajb2,Socs3,Map3k8,Serpinb9,Wdfy1,Ext1,Xaf1,Pou2f2,Leng9,Tnfrsf1b,Card6,Junb,Gbp7,Lgals9,Hopx,Slfn4 |
| 1.491e-06 | -13.42 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN | 178 | 34 | 15632 | 1249 |
Oas2,Rapgef2,Plscr1,Pdlim7,Akt3,Rims3,Lcp2,Rgl1,Pde4b,Acsl1,Fpr1,Kif3c,Cacnb3,Itga5,Tnfsf4,Scarf1,Acvr1,Nr3c1,Ankrd17,Itpr1,Stat5a,Tnfaip3,Klf7,Aff1,Atp2b4,Crim1,Gng11,Cd34,Dmxl2,St3gal6,P2ry14,Ccnd2,Hif1a,Hlx |
| 1.495e-06 | -13.41 | regulation of cell development | biological process | GO:0060284 | 1092 | 115 | 20694 | 1406 |
Sphk1,Rap1gap2,Crkl,Trib1,Tlr2,Tomm70a,Tnfrsf1b,Rgs14,Trip10,Gfi1,Scarf1,Notch1,Scn1b,Lif,Mul1,Lpar1,Lrp4,Map4k4,Sema3c,Gpr68,Nr3c1,Stat3,Hap1,Ldlr,Eif4g2,Map2k1,Spen,D16Ertd472e,Ifrd1,S1pr2,Triobp,Edn1,Stap1,Sipa1l1,Sema4c,Carmil1,Flrt2,Lrp8,Csf1,Fas,Myc,Pde5a,Dync1i2,Ptk2,Zeb1,Rac3,Prag1,Abcb1a,Mecp2,Vegfc,Mov10,Kif3c,Tspo,Ehd1,Pdpn,Slamf8,Hdac1,Ust,Cx3cr1,Rab21,Sdc2,Dbnl,Itpr1,Lyn,Cav1,Kremen1,Myadm,Pbx1,Cdk5r1,Clcf1,Mdm2,Sirt1,Il15ra,Fubp1,Il1b,Hmga2,Cyfip1,Il6,Kdm4a,Casz1,Hif1a,Mmd,Cflar,Jag1,Plk2,Rapgef2,Lhx2,Cd38,Sema4a,Bmp2,Mycl,Nlgn2,Mosmo,Igf1r,Zhx2,Notch2,Kat2b,Ccl5,Bcl6,Ednrb,Mark2,Agrn,Kdr,P2ry12,Tcf4,Fzd1,Zswim4,Tnf,Cx3cl1,Il1a,P2ry2,Nck1,Met,Etv5,Katna1 |
| 1.506e-06 | -13.41 | regulation of natural killer cell mediated immunity | biological process | GO:0002715 | 53 | 15 | 20694 | 1406 |
H60b,Lgals9,Pvr,Il18rap,Tap1,Nectin2,Clec2d,Il12b,Rasgrp1,Pik3r6,Raet1e,Klrk1,Stat5a,Tap2,Serpinb9 |
| 1.509e-06 | -13.40 | GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDC_UP | 186 | 35 | 15632 | 1249 |
Etv6,Ppp4r2,Irf8,Cd274,Gem,Brd2,Gja1,Il15ra,Dcbld2,Tfec,Plat,Tnip1,Cacnb3,Fpr1,Map3k8,Cd200,Smc5,Lztfl1,Mdm2,Dtnb,Tbc1d1,Rffl,Slc44a1,Ttc39c,Jun,Birc2,Tcf4,Adhfe1,Gypc,Spryd7,Slc25a25,F11r,Trim13,Nxf1,Fas |
| 1.509e-06 | -13.40 | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | MSigDB lists | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | 186 | 35 | 15632 | 1249 |
Serpinb9,Il18,Odc1,Cd200,Ptprj,Ebi3,Pmepa1,Rgs1,Fosb,Vps54,Cd86,Hopx,Igsf9,Txn1,Parp12,Tdrd7,Cxcl2,Ccrl2,Plscr1,Phlda1,Noc4l,Arrdc4,Gbp3,Prnp,Lif,Prdm1,Mdfic,Ripk3,Gnb4,Cd83,Batf,B4galt4,Swap70,Axl,Casp3 |
| 1.509e-06 | -13.40 | GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN | 186 | 35 | 15632 | 1249 |
Plek,Dusp6,Zc3h12c,Flrt2,Plod2,Nrp2,Hivep3,Egr3,Gng4,Il13ra1,Trib1,Nr4a3,Rab20,Osbpl3,Tagap,Igf2bp2,Vegfc,Gfi1,Cst7,Itgav,Tiparp,Rhof,Gpr35,Slc15a3,Egr2,Chst11,Dusp4,Malt1,Ier2,Egr1,Plagl1,Lipg,Rgs3,Mdfic,Ahr |
| 1.516e-06 | -13.40 | Th1 and Th2 cell differentiation | KEGG pathways | mmu04658 | 87 | 23 | 7931 | 713 |
Maml2,Il2rg,Nfkbib,Nfkbia,H2-Aa,Notch1,Il12rb1,Jun,Tyk2,Nfkb1,Stat1,H2-Eb1,Il12b,Notch2,Il4ra,Ikbkg,Jak2,H2-Ab1,Jag1,Stat4,Fos,Stat5a,Nfkbie |
| 1.516e-06 | -13.40 | Th1 and Th2 cell differentiation | KEGG pathways | ko04658 | 87 | 23 | 7931 | 713 |
Stat1,Nfkb1,Tyk2,Jun,Il12rb1,Notch1,H2-Aa,Nfkbia,Il2rg,Nfkbib,Maml2,Nfkbie,Stat5a,Fos,Stat4,Jag1,Il4ra,Jak2,H2-Ab1,Ikbkg,H2-Eb1,Notch2,Il12b |
| 1.517e-06 | -13.40 | negative regulation of angiogenesis | biological process | GO:0016525 | 112 | 23 | 20694 | 1406 |
Ccl2,Col4a2,Pf4,Adrb2,Thbs1,Plk2,Pml,Sema4a,Cx3cr1,Cxcl10,Pde3b,Spred1,Lif,Mecp2,Tcf4,Notch1,Hhex,Stat1,Klf2,Rgcc,Pgk1,Serpine1,Spry2 |
| 1.520e-06 | -13.40 | HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY | MSigDB lists | HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY | 46 | 15 | 15632 | 1249 |
Gclm,Srxn1,Nqo1,Gsr,Junb,Txn1,Txnrd1,Sod2,Prdx1,Gclc,Abcc1,Glrx,Hhex,Cdkn2d,Prnp |
| 1.520e-06 | -13.40 | MODULE_108 | MSigDB lists | MODULE_108 | 46 | 15 | 15632 | 1249 |
Ccr1,Cx3cr1,Ccl12,Cxcl14,Ccl2,Fpr2,Il1a,Cxcl10,Cx3cl1,Fpr1,Plaur,Pf4,Cxcl1,Plau,Ccl4 |
| 1.524e-06 | -13.39 | GO_MYELOID_CELL_HOMEOSTASIS | MSigDB lists | GO_MYELOID_CELL_HOMEOSTASIS | 83 | 21 | 15632 | 1249 |
Lyn,Jmjd6,Hmox1,Tmod3,Hcar2,Jak2,Prdx1,Hcls1,Adar,Klf2,Bcl6,Ptpn2,Pde4b,Axl,Arid4a,Bcl2l11,Inhba,Ikzf1,Casp3,Ampd3,Il6 |
| 1.533e-06 | -13.39 | whole membrane | cellular component | GO:0098805 | 1093 | 115 | 20747 | 1409 |
Lipe,Adrb2,Acsl5,Rubcnl,Lrp8,Aftph,Fcgr2b,Tnf,Abcc1,Acsl1,Asah2,Mul1,Rap2c,Ptch1,Traf2,Sec24b,Lyn,Sdc4,Kmo,Pmepa1,Mcoln2,Stx6,Hmox1,Rhoq,Ppp2r1b,Cd55,Rmdn3,Pgk1,Hck,Gpc1,Bcl2a1a,Tomm70a,Hk2,Sema4c,Lrp4,Kdr,Tlr2,Treml4,Sphk1,Bcl2a1d,Snx10,Cd38,Snx2,P2ry12,Sec24a,Ptgs2,Rab32,Slc9a1,Birc2,Ednrb,Rffl,Fas,Pdpn,Itpr1,Ehd1,Slc2a1,Birc3,Fcgr1,Bcl2a1b,Ppp1r15a,Psd,Sele,Cnp,Chmp4b,Armcx6,Grk3,Tspo,Casp3,Pikfyve,Gja1,Wdr59,Syne2,Abcc4,Bnip3,Snn,Plscr1,Tlr6,Cflar,Slc15a3,Tlr1,Ldlr,Kcna3,Actb,Casp8,Hspa1a,Rab10,Prkar2b,Cd274,Myo1b,Agpat4,Cd14,Ezr,Trim14,Prnp,Fcho2,Lcp2,Angpt1,Ass1,Src,Eno1,Igf1r,Gk,Myadm,Slc48a1,Cav1,Rsad2,Rab21,Slc44a1,Icam1,Hk1,Eno2,Slc29a3,Tnfrsf1b,Jak2,H2-Eb1 |
| 1.593e-06 | -13.35 | MARKS_HDAC_TARGETS_UP | MSigDB lists | MARKS_HDAC_TARGETS_UP | 21 | 10 | 15632 | 1249 |
Bcl2l11,Ccne1,Txn1,Gadd45b,Fas,Casp8,Tnfsf10,Casp3,Glrx,Apaf1 |
| 1.593e-06 | -13.35 | WANG_TNF_TARGETS | MSigDB lists | WANG_TNF_TARGETS | 21 | 10 | 15632 | 1249 |
Vcam1,Il6,Sele,Csf3,Mmp13,Tnfaip3,Nfkbia,Gdf15,Traf1,Jun |
| 1.593e-06 | -13.35 | BIOCARTA_CASPASE_PATHWAY | MSigDB lists | BIOCARTA_CASPASE_PATHWAY | 21 | 10 | 15632 | 1249 |
Casp1,Birc3,Casp7,Birc2,Casp4,Casp8,Casp3,Cycs,Casp2,Apaf1 |
| 1.614e-06 | -13.34 | membrane | cellular component | GO:0016020 | 9180 | 708 | 20747 | 1409 |
Lrrc25,Tmem219,Ch25h,Kctd12,Il1a,AA467197,Gpr141,Mx1,Irs2,Fam129a,Clec4e,Marcksl1,Casp4,Gch1,Rnd1,Hspa2,Gbp3,Tnfrsf1b,Prkce,Jak2,Rrbp1,Tmem171,Fam72a,Tmem184b,Dtx3l,Eno2,Ptges,Gm12185,Bcl2a1b,Clcn7,Agtrap,Pfkl,Stx11,Sh3bp4,Dse,Snn,Cpd,Vasn,Ccdc88b,Ripk3,Raet1e,Wdr59,Rab20,Ppm1l,Ankrd17,Ptprj,Eva1b,Ldlr,Arrdc4,Il6,Bcl2a1d,Samhd1,Cenpj,Fcgr4,Cept1,B3gnt5,Snx2,Cish,Phlpp2,Acvrl1,Tgtp2,Gsdmd,Fcgr1,Fas,Met,Rap1gap2,Rubcnl,Scyl2,Spred3,Gm5150,Rnf19b,Klrk1,Slc37a3,Igsf8,Map2k1,Fam162a,Glipr2,Plek,Adgre4,Fnbp1l,Tgtp1,Rmdn3,Tapbpl,Gpr84,Rnf24,Gcnt2,Slc31a2,Hspa1a,Pkp4,Hilpda,Smox,Pigv,Ass1,Lpcat2,Cd300lf,Slc30a4,Cd69,Tnfsf15,Fzd1,4932438A13Rik,Tbc1d13,Slc48a1,Cox18,Ccnd1,Slamf9,Icam1,Clic5,Iigp1,Tmem67,Tmem26,Gbp2,Prokr1,Plscr1,Tlr6,Rpgrip1l,Notch1,Slc49a4,Slc7a11,Abcc4,Gca,Slc39a4,Akt3,H2-Q6,H2-T24,Cpeb4,Stxbp1,Slc7a8,Sphk1,Rac3,Chst11,Icosl,Marcks,Slc25a22,Cd83,Tlr2,Htr2b,Sec24a,Atp11b,Itga9,Rtn1,Cysltr2,Mgat1,Spaca6,Igtp,Dnajb2,Ptgs2,Slc9a1,Tor1aip2,Cd34,Birc3,Slc2a1,Fchsd2,Rffl,Ednrb,Acp2,Srgn,Cxcl9,Ly75,Cd180,Acpp,Traf5,Fut8,Acsl1,Abcb1a,Inpp5b,Il2rg,Pmepa1,Frmd6,Pim1,Kmo,Fscn1,Rhof,Ogfrl1,Rhoq,Rtp4,Arid4a,Lrrc8c,Rgs14,Psd4,Prkar2b,Gng12,Myo1b,Rgs1,Nod1,Spn,Mmp25,St3gal5,Src,Gsr,Tlr3,Angpt1,Dtx2,Gng4,B4galt4,Plekha4,Eno1,Mtus1,Myadm,Plau,Phf11c,Tmem123,Tmem176a,Slc7a5,Cnp,Trib3,Chmp4b,Armcx6,Mpp7,Cdk5r1,Spry2,Slc25a37,F830016B08Rik,Tnfsf14,Ptpn2,Selenow,Degs2,Filip1l,Gng11,Dnaja1,Bnip3,Nlrp3,Sirt1,Sdc2,Syne2,Clec5a,Ifi47,Rtn2,Clic4,Kcna3,Dst,Crkl,Rnf34,Cd38,Ogfr,Il18rap,Gpr68,Csf3r,Higd1a,Cacnb3,Gramd1a,Crim1,Nlgn2,Myd88,Piezo1,Itpr1,Mosmo,Bmp2,Itgav,Tulp3,Pcx,Errfi1,Plaur,Gnb4,Stau1,Tnfsf4,Gypc,Sco1,Pde3b,Mul1,Aftph,Slc39a14,Pilrb1,Fcgr2b,Ric1,Slc12a9,Clmp,Irak3,Ppp2r5a,Homer1,Sema4c,Pcdh7,Bcl2a1a,Ms4a6c,Plpp3,Tlr9,Sema3c,Scarf1,St3gal3,Tmc3,Ust,Mfsd7a,Prnp,Atp13a1,Lnpk,Gpr85,Slc44a1,Cav1,Stat3,Ms4a4b,Tarm1,Pvr,Rras2,Hk1,H2-Q4,Cd74,Cd300e,Tmem176b,Cp,Tmem178,Cgas,Gja1,Pnpt1,Gm4951,St7,Slc31a1,Fam241a,Sgms2,Ksr1,Actb,Casp8,Ly6c2,Cflar,Irak2,Ktn1,Tlr1,Dbnl,Carmil1,Slamf8,Calhm6,Clcn5,Gpr35,Kdr,P2ry12,Bcl2l11,Zhx2,Birc2,Csf1,Antxr1,Sell,Micall2,Minpp1,Treml2,Sdc1,Ap3m2,Sod2,Dusp2,Serp1,Vasp,Uaca,Prpf38a,Igsf9,Lrp8,Tent4a,Cd80,Katna1,Klra2,Cd200r4,Cemip2,Mmp14,Znrf3,Itga4,Adgrg6,Spred1,Gpr132,Hk2,Rapgef2,Apba1,Stx6,Pgk1,Flrt2,Gpc1,Cdc42ep4,Tomm70a,Pilrb2,Nr4a1,Shisa3,Olfr56,Nox1,Phf11b,Phf11a,H2-Ab1,Fcho2,Bfar,Ifnar1,Slc13a3,Smpdl3b,Ntng2,Daam1,Igf1r,1600014C10Rik,Mlkl,H2-Eb1,Rnf19a,Sele,Ccr3,Cop1,Casp2,Rnf31,Swap70,Pdgfc,Gm5431,Fos,Pml,Tspo,Adora2b,Fpr2,Lrp11,Cyth3,Etnk1,Spint2,Noc4l,Stra6l,Treml4,Nampt,Dnajb4,Ifitm1,Susd6,Slc39a13,Lratd2,Ebi3,Flnb,Scn1b,Atp6v1d,Extl2,Osbpl3,Ly6a,Rhoh,Tpst1,F11r,Plpp1,Slc4a7,Trp53i11,Axl,Ubr4,Zc3h12a,Acsl5,Rab19,Bambi,Pdgfb,Myo10,Ccr1,Gna15,Dhrs9,Socs7,Cd40,Spata13,Pik3r5,Pdgfrb,Hcls1,Palld,Plaat3,Rnf114,Dpy19l1,St3gal6,Fndc3a,H2-M2,Fpr1,P2ry2,Vegfc,Pik3cd,Acvr1,Cd82,Agrn,Ccnd2,Calcrl,Pdzd11,Cd200,Gm4841,9930111J21Rik1,Psd,Vrk2,Pikfyve,Htr2a,H2-Q7,Cers6,Tnfsf9,Uchl1,Pik3r6,Ms4a6d,Tap2,Cd86,Atp11a,Golga3,Clec2d,Rnf139,Cacna1d,Dio2,Slc7a2,Ptk2,Tor1aip1,Adam19,Fgr,Mtdh,Cxcl10,Layn,Gbp2b,Trip10,Dcun1d3,Nos2,Ero1l,Notch2,Ptger4,Dram1,Hsd17b12,Ets2,Rnf145,Clec4n,Mdm2,Gbgt1,Atp10a,Rilpl1,Lipe,H60b,Prrg4,Ccrl2,Xkr8,Kif3c,Tnf,Phlpp1,Cd164,Ranbp2,Bst1,Stat2,Olr1,Dgka,Jag1,Ppp2r1b,Cd55,Hck,Trem1,Il12b,Cmklr1,Slc16a3,P2ry14,Cd14,Cldnd1,Jmjd6,Nectin4,Mark2,Nectin2,Sh3bgrl2,Pde4b,Orai2,Arf4,Trim14,Xrn1,Chic2,Atp2b4,Abr,Rab11fip1,Gk,Znrf1,Samsn1,Tnfrsf14,Slco3a1,Bcorl1,Slc29a3,Dmxl2,Slc2a6,Ppp1r15a,Casp3,Plod2,Rhbdf2,Grk3,Rhou,H2-T22,Clec4d,Tspan3,Cx3cr1,Flrt3,Rnd3,Stoml1,Tmeff1,Rgs3,Itgb8,I830077J02Rik,Snx10,Il12rb1,Plod3,Stxbp3,Rab32,Sgcb,Il18,Il15ra,Sema4a,Thbs1,Pdpn,Cd302,Hsd17b7,Lst1,Mx2,Crbn,P2ry13,Lpar1,Ier3,Gpsm2,Asah2,Il13ra1,Nr3c1,Marco,Slc28a2,Rap2c,Siglece,Traf2,F10,Kremen1,Slc25a12,Tyk2,Dcbld2,Adgrl2,Ikbke,Adap2,Mcmbp,Adora2a,Cd274,Itgal,Agpat4,Nck1,Reps1,Rab10,Scimp,Ezr,Vezt,Lcp2,Milr1,Rsad2,Cx3cl1,Irgm1,Nod2,H2-T10,Nfkbia,Dock4,Plekhn1,Rab21,Acvr1b,Mfap3l,Plekhf2,Msr1,Trim13,Rims3,Kitl,Pgap2,Socs3,Abcc5,Slamf7,Dnaja2,Rhoc,Itga5,Tnfrsf8,Ms4a6b,Mppe1,Ddx58,Tmem229b,Slc30a1,Oas3,Spire1,Tmtc2,Tnfsf10,S100a8,Tnfsf8,Slc15a3,Enpp4,Rab9,Cdc42ep2,H2-Aa,Nrp2,Ptafr,Whamm,Irgm2,Gpr18,Plekha2,S1pr2,Hvcn1,Aida,Igsf6,Arl4a,Il4ra,Tapbp,Kcnj2,Fzd5,Mitd1,Vcam1,Ehd1,St3gal1,Slc43a3,Xcr1,Socs1,Htra1,Slc25a25,Sipa1l1,Hcar2,Gem,Tap1,Pstpip2,Adrb2,Abcc1,Slc16a1,Syk,Caml,Flt1,Rasgrp1,Crlf3,Mcoln2,Ptch1,Procr,Ptgir,Lnpep,Grina,Lyn,Sec24b,Sdc4,Gpd2,Ap3b1,Pilra,Ext1,Lrp4,Phf11d,Hmox1 |
| 1.619e-06 | -13.33 | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | MSigDB lists | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | 64 | 18 | 15632 | 1249 |
Atf3,Egr1,Kitl,Thbs1,Stat5a,Nr4a1,Dusp1,Plk2,Fos,Klf2,Itpr1,Bcl6,Fosb,Btg2,Sat1,Egr2,Zfp36,Pcx |
| 1.619e-06 | -13.33 | GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN | MSigDB lists | GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN | 64 | 18 | 15632 | 1249 |
Lif,Socs3,Ptger4,Socs1,Il12b,Il18,Lyn,Hcls1,Clcf1,Il15,Jak2,Ccl5,Ptpn2,Osm,Cd40,Cav1,Il6,Stat3 |
| 1.620e-06 | -13.33 | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | MSigDB lists | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | 90 | 22 | 15632 | 1249 |
Cdkn1a,Psmb10,Trib3,Psmb6,Malt1,Psme1,Rasgrp1,Psma6,Nfkbie,Rictor,Mdm2,Phlpp1,Nfkbib,Psme2,Akt3,Rel,Psmb9,Psmd10,Ikbkg,Psmb8,Nr4a1,Nfkbia |
| 1.621e-06 | -13.33 | GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | 163 | 32 | 15632 | 1249 |
Ube2f,Cd83,Batf,Fgr,Arrdc4,Ubash3b,Rhoh,Cpd,Glipr2,Nfkbie,Ankrd17,Traf2,Cyfip1,Psmb9,N4bp1,Cst7,Stat5a,Dusp1,Nfil3,Ralgds,Gbp2b,Actb,Ttc39b,Map3k8,Arid5b,Nsmaf,Trib1,Ptger4,Arl5c,Fosb,Vps54,Myadm |
| 1.637e-06 | -13.32 | GO_NEGATIVE_REGULATION_OF_NITROGEN_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NITROGEN_COMPOUND_METABOLIC_PROCESS | 1351 | 155 | 15632 | 1249 |
Nfxl1,Cmklr1,Igf2bp2,Tfec,Zhx2,Zc3h12a,Pim1,Pdgfb,Btg2,Ifi208,Nfkbid,Hap1,Jarid2,Arid4a,Txn1,Junb,Bmp2,Notch1,Daxx,Mdfic,Relb,Irf2,Mxd1,Hhex,Nfkbil1,Pml,Hif1a,Kdm4a,Setdb2,Kdm5b,Ccnd1,Mdm2,Acvrl1,Ifi213,Dusp1,Src,Ifi205,Rbbp8,Eno1,Dr1,Hcls1,Gfi1,Tnfsf4,Stat1,Irf1,Timeless,Sirt1,Ifi203,Hat1,Dach1,Irf8,Il10,Ptch1,Hinfp,Ciita,Gclc,Adar,Atp2b4,Atf3,Lrp8,Egr1,Etv3,Trim13,Prnp,Nlrp3,Edn1,Ikzf1,Peli1,Myc,Nfkbia,Ezr,Nlrc5,Psmd10,Jun,Irak2,Nfkb2,Keap1,Il1b,Hmox1,Trib3,Nr4a3,Arid5b,Sap30,Ddit4,Fzd1,Cdyl,Ccl5,Gja1,Hopx,Ppp1r15a,Irf7,Fosb,Pbx1,Cd38,Tnfaip3,Irak3,Plk3,Parp10,Aim2,Prdm1,Rnf139,Zfp281,Stat3,Mecp2,Hdac1,Aebp2,Prdx5,Tnf,Arid5a,Zmynd15,P2ry13,Bcl6,Ifi209,Tax1bp1,Ccl4,H3f3b,Nfil3,Tlr9,Cpeb4,Mtdh,Trib1,Lpar1,Ifi204,Zeb1,Spen,Ifi211,Trim14,Trim21,Med13,Zfp36,Etv6,Atm,Ahrr,Jdp2,Ednrb,Nfkb1,Pid1,Rel,Mov10,Cav1,Mndal,Cd34,Tspo,Ifi207,Rbl1,Ahr,Nck1,Bcor,Cdk5r1,Ifi214,Nr1h3,Eif2ak2,Hmga1,Ets2,Cited2 |
| 1.645e-06 | -13.32 | regulatory region nucleic acid binding | molecular function | GO:0001067 | 981 | 107 | 20217 | 1400 |
Jarid2,Bcl6,Aebp2,H3f3b,Arid5b,Jdp2,Mafg,Dach1,Zfp513,Mycl,Ifi214,Nr4a3,Fos,Zeb1,Mxd1,Ciita,Nfxl1,Lhx2,Pou2f2,Batf,Tiparp,Nfkb2,Hmga1,Pcgf5,Ifi207,Ifi208,Batf2,Hif1a,Stat4,Nr3c1,Klf8,Junb,Klf7,Egr3,Jun,Rbl1,Nfil3,Ifi204,Ifi213,Ets2,Kat2b,Egr1,Dr1,Atf3,Notch1,Irf2,Foxp4,Mndal,Arid5a,Klf6,Klf3,Ifi209,Tal2,Plagl1,Zfp281,Ier2,Max,Nr1h3,Nr4a1,Nlrc5,Sirt1,Tfec,Bcor,Sp140,Prdm9,Etv6,Prdx5,Ifi205,Hhex,Tcf4,Stat5a,Irf8,Gfi1,Ikzf1,Spic,Ifi203,Rel,Egr2,Hinfp,Relb,Irf4,Etv5,Irf1,Hivep2,Ahr,Stat2,Etv3,Stat1,Eno1,Zbtb5,Myc,Rfx5,Maff,Tnf,Stat3,Kdm6b,Cebpd,Ifi211,Hdac1,Lmo4,Mafk,Irf7,Prdm1,Fosb,Pbx1,Nfkb1,Arid4a |
| 1.653e-06 | -13.31 | regulation of epithelial cell apoptotic process | biological process | GO:1904035 | 89 | 20 | 20694 | 1406 |
Itga4,Hdac1,Thbs1,Zfp36,Angpt1,Il10,Ccl12,Cd40,Igf1r,Jak2,Kdr,Cflar,Col18a1,Tnfaip3,Serpine1,Hmox1,Icam1,Rgcc,Tnf,Nupr1 |
| 1.653e-06 | -13.31 | G1/S transition of mitotic cell cycle | biological process | GO:0000082 | 67 | 17 | 20694 | 1406 |
Acvr1b,Ccnd2,Rgcc,Ccnd1,Rhou,Plk3,Cdkn2d,Inhba,Crlf3,Gpr132,Plk2,Pim2,Acvr1,Hinfp,Rbbp8,Ccne1,Cdkn1a |
| 1.653e-06 | -13.31 | negative regulation of reactive oxygen species metabolic process | biological process | GO:2000378 | 67 | 17 | 20694 | 1406 |
Ptger4,Hk2,Atp2b4,Hif1a,Cflar,Cav1,Tspo,Trim30a,Cd34,Bnip3,Sirt1,Acp5,Stat3,Zc3h12a,Il10,Hp,Birc3 |
| 1.653e-06 | -13.31 | regulation of B cell proliferation | biological process | GO:0030888 | 67 | 17 | 20694 | 1406 |
Bcl6,Cd38,Prdm1,Tlr9,Peli1,Cdkn1a,Cd74,Il10,Fcgr2b,Atm,Cd40,Casp3,Bst1,Lyn,Irs2,Ahr,Clcf1 |
| 1.662e-06 | -13.31 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN | 111 | 25 | 15632 | 1249 |
Fabp3,Me1,Dock4,Cst7,Slfn8,Ccl2,Slamf8,Tgfbi,Fcho2,Clec5a,Frmd4a,Mmp9,Rtn1,Cxcl1,Ccl4,Slfn9,Klf2,Pid1,Slc7a8,Rgl1,Dach1,Pla2g7,Cxcl2,Rasgrp1,Slpi |
| 1.662e-06 | -13.31 | LIU_VMYB_TARGETS_UP | MSigDB lists | LIU_VMYB_TARGETS_UP | 111 | 25 | 15632 | 1249 |
Rhoq,Stard5,Phlpp1,Arhgap26,Hspa2,Psip1,Crim1,Bcor,Tpi1,Usp25,Mapkapk2,Slco3a1,Isg20,Sap30,Plscr1,Nmi,Mmd,Jag1,Slc31a2,Lnpep,Clic4,Sec24a,Prkar2b,Glrx,Pim2 |
| 1.670e-06 | -13.30 | GO_GRANULOCYTE_MIGRATION | MSigDB lists | GO_GRANULOCYTE_MIGRATION | 58 | 17 | 15632 | 1249 |
Ccl22,Itga9,Pik3cd,Cx3cl1,Trem1,Il1b,Ccl3,Ccl4,Csf3r,S100a8,Pde4b,Ccl12,Syk,Ccl5,Cxcl2,Edn1,Ccl2 |
| 1.670e-06 | -13.30 | GAJATE_RESPONSE_TO_TRABECTEDIN_UP | MSigDB lists | GAJATE_RESPONSE_TO_TRABECTEDIN_UP | 58 | 17 | 15632 | 1249 |
C1ra,Ccng2,Il6,Fos,Asns,Casp4,Cdkn1a,Tnfaip3,Clic4,Tgfbi,Phyh,Il18,Isg15,Atf3,Oasl1,Nupr1,Dusp5 |
| 1.670e-06 | -13.30 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_DN | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_DN | 171 | 33 | 15632 | 1249 |
Acsl5,Dek,Cdkn1a,Glrx,Ebi3,Endod1,Il13ra1,Rab20,Cxcl10,Fam111a,Il12rb1,Fam72a,Tdrd7,AA467197,Gch1,Gna15,Rbms2,Rbl1,Plk3,Magohb,Ddx58,Rnf135,Fgr,Abcb1a,D1Ertd622e,Mmp14,Pnp2,Tapbp,Parp9,Mlkl,Gpr68,Bcl6,Rbbp8 |
| 1.676e-06 | -13.30 | cation homeostasis | biological process | GO:0055080 | 711 | 82 | 20694 | 1406 |
Ccl2,Rab20,Gpr35,Adrb2,Slc30a1,Slc9a1,Slamf8,Sco1,Cp,Pml,Mllt6,Ccr1,Cx3cr1,Cmklr1,Kdr,Atp2b4,Ptger4,P2ry2,Ccl3,Cx3cl1,Mt2,Cxcl1,Cacna1d,Sod2,Fpr1,Ednrb,Slc4a7,Htr2a,Slc12a9,Myc,Bnip3,Ccr3,Ptgir,Cutc,Nox1,Ccrl2,Edn1,Atp13a1,Cd40,Clic4,Ccl5,Cxcl2,Prnp,Cacnb3,Dmxl2,Mt1,Cd38,Slc39a13,Xcr1,Snx10,Lcn2,Fpr2,Hap1,Hif1a,Cxcl10,Mafg,Tmem178,1600014C10Rik,Ero1l,Gna15,Rmdn3,Lpar1,Swap70,Slc39a14,Tmtc2,Il1b,Grina,Itpr1,Gja1,Slc39a4,Htr2b,Itgav,Jak2,Marcksl1,Slc30a4,Slc31a1,Prkce,Hmox1,Slc31a2,Gpr18,Cxcl3,Cav1 |
| 1.684e-06 | -13.29 | MARKEY_RB1_CHRONIC_LOF_DN | MSigDB lists | MARKEY_RB1_CHRONIC_LOF_DN | 104 | 24 | 15632 | 1249 |
Il6,Cp,Htra1,Edn1,Fabp7,Pla2g7,Mmp13,Kdm5b,Sqstm1,Ccl12,Plac8,Msr1,Slfn4,Lcp2,Gng11,Cd14,Slfn3,Hmox1,Nupr1,Uchl1,Rnf19b,Slco3a1,Clec4d,Ms4a6d |
| 1.691e-06 | -13.29 | SMALL_CYTOKINES_CXC | prosite domains | PS00471 | 10 | 7 | 13278 | 1037 |
Cxcl3,Cxcl9,Cxcl10,Cxcl1,Pf4,Cxcl2,Cxcl11 |
| 1.693e-06 | -13.29 | peptidyl-tyrosine modification | biological process | GO:0018212 | 146 | 27 | 20694 | 1406 |
Tpst1,Map2k1,Map2k4,Met,Dyrk2,Src,Hck,Stat5a,Eif2ak2,Pdgfb,Lif,Syk,Flt1,Kdr,Ptk2,Axl,Sla,Pdgfrb,Lyn,Osm,Il12rb1,Tyk2,Il15,Hk1,Fgr,Igf1r,Jak2 |
| 1.702e-06 | -13.28 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN | 179 | 34 | 15632 | 1249 |
Srxn1,Ppp4r2,Stat4,Rnf19a,Eno2,Jarid2,Tnfrsf1b,Gja1,Map4k4,Atp6v1d,Serpine1,Igsf8,Arf4,Actb,Il1rn,Nfkb2,Idi1,Ppp2r2a,Abcc1,Cdkn1a,Ptger4,Slc31a1,Ifrd1,Stat5a,Ehd1,Ezr,Bcl2l11,Phldb1,Slc7a11,Il15,Ahr,Ch25h,Cd74,Gmppb |
| 1.702e-06 | -13.28 | GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_DN | MSigDB lists | GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_DN | 179 | 34 | 15632 | 1249 |
Ifnar1,Pik3r5,Ass1,Lrp4,Plac8,Ifit1bl1,D16Ertd472e,Rgs14,Cish,Irf4,Dock10,Nupr1,Itga4,St3gal6,Nod1,Rras2,Slfn5,Irak3,Hvcn1,Ifit1bl2,Osm,Hopx,Klf2,Akt3,Rap1gap2,Dyrk2,Tnfsf4,Il18,Cacnb3,Ust,Fam102b,Cflar,Orai2,Frmd6 |
| 1.702e-06 | -13.28 | GSE25087_FETAL_VS_ADULT_TREG_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TREG_UP | 179 | 34 | 15632 | 1249 |
Cyfip1,Slc7a11,Lrp4,Agrn,Nfkbie,Kdm5b,D1Ertd622e,Casp3,Ccnd2,Psme1,Csrnp1,Rhoc,Sdc4,Batf,Gnb4,Rras2,Samsn1,Eif4g2,Mthfd1l,Cxcl2,Timeless,Psme2,Tnip3,Tlr2,Ier3,Cd200,Stat1,Stip1,Stard7,Esd,Il1b,Vrk2,Cmpk2,Notch2 |
| 1.702e-06 | -13.28 | GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP | MSigDB lists | GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP | 148 | 30 | 15632 | 1249 |
Fam43a,Psmb9,Ly75,Gbp4,Gbp9,Pde5a,Samd9l,Il18bp,Mcoln2,Itga4,Plk3,Ddx60,Papss2,Gbp3,Calcrl,Ddx58,Ahr,Ncoa7,Gbgt1,Degs2,Slc25a12,Hivep3,Socs3,Pcgf5,Mmp25,Rcn1,Ldlr,Rbms1,Cdkn1a,Epsti1 |
| 1.705e-06 | -13.28 | positive regulation of granulocyte macrophage colony-stimulating factor production | biological process | GO:0032725 | 11 | 7 | 20694 | 1406 |
Il1b,Ddx58,Rasgrp1,Il12b,Il18,Tlr9,Syk |
| 1.706e-06 | -13.28 | cellular ion homeostasis | biological process | GO:0006873 | 644 | 76 | 20694 | 1406 |
Grina,Il1b,Slc39a14,Swap70,Cav1,Cxcl3,Gpr18,Prkce,Hmox1,Slc31a2,Marcksl1,Slc31a1,Itpr1,Slc39a4,Gja1,Htr2b,Itgav,Jak2,Lcn2,Hap1,Fpr2,Xcr1,Cd38,Mt1,Slc39a13,Cacnb3,Dmxl2,Prnp,Rmdn3,Lpar1,Gna15,Ero1l,Tmem178,1600014C10Rik,Cxcl10,Mafg,Hif1a,Ptk2,Ptgir,Ccr3,Myc,Bnip3,Htr2a,Ednrb,Slc4a7,Fpr1,Ccl5,Cxcl2,Clic4,Atp13a1,Cd40,Nox1,Ccrl2,Edn1,Cx3cr1,Pml,Ccr1,Sco1,Cp,Slc9a1,Slamf8,Adrb2,Slc30a1,Rab20,Gpr35,Ccl2,Cacna1d,Cxcl1,Cx3cl1,Mt2,P2ry2,Ccl3,Atp2b4,Ptger4,Cmklr1,Kdr |
| 1.708e-06 | -13.28 | GO_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | MSigDB lists | GO_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 133 | 28 | 15632 | 1249 |
Nod1,Bmp2,Daxx,Mdfic,Tlr6,Il1a,Mul1,Edn1,Dbnl,Nod2,Mid1,Gadd45g,Eif2ak2,Gadd45b,Map3k6,Tnf,Syk,Traf2,Il1b,Nox1,Sema4c,Tlr3,Tlr9,Zc3h12a,Ripk2,Lyn,Rasgrp1,Fzd5 |
| 1.709e-06 | -13.28 | Toll Like Receptor 9 (TLR9) Cascade | REACTOME pathways | R-MMU-168138 | 83 | 22 | 8608 | 757 |
Ppp2r1b,Dusp6,Jun,Nfkbib,Dusp4,Nfkbia,Mapkapk2,Peli1,Nfkb2,Irak2,Nod1,Map3k8,Fos,Tab2,Myd88,Ikbkg,Nod2,Irf7,Map2k4,Ripk2,Tlr9,Nfkb1 |
| 1.710e-06 | -13.28 | Downstream signaling events of B Cell Receptor (BCR) | REACTOME pathways | R-MMU-1168372 | 179 | 36 | 8608 | 757 |
Pdgfrb,Nfkbia,Nfkbib,Nr4a1,Ppp2r1b,Cd86,Pdgfb,Nfkb1,Cdkn1a,Kitl,Irs2,Phlpp2,Ppp2r5a,Src,Rictor,Psme2b,Nfkbie,Rasgrp1,Psmb9,Pik3cd,Rel,Psmb6,Psme1,Mdm2,Met,Ier3,Psmb8,Psmb10,Ikbkg,Psme2,Trib3,Psma6,Cd80,Malt1,Psmd10,Phlpp1 |
| 1.717e-06 | -13.27 | GSE11057_CD4_EFF_MEM_VS_PBMC_DN | MSigDB lists | GSE11057_CD4_EFF_MEM_VS_PBMC_DN | 187 | 35 | 15632 | 1249 |
Mxd1,Cd180,Cd74,Tnfrsf8,Spred1,Pdgfc,Hk3,Hvcn1,Syk,Aoah,Tcf4,Tet2,Rhoq,Slc15a3,B3gnt5,Rtn1,Tlr2,Rab20,Acsl1,Grina,Cd300lf,Siglece,Notch2,Jak2,Snn,Nfil3,Prkar2b,Trem1,Fmnl2,Dusp6,Plek,Slc31a2,Gbgt1,Slc2a6,Plscr1 |
| 1.717e-06 | -13.27 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP | 187 | 35 | 15632 | 1249 |
Dach1,Nampt,Hk1,Mov10,Ubr4,Casp4,Oas2,Rasgrp1,Ppa1,Acvr1b,Rcn1,Rcsd1,Jak2,Znrf1,Irak2,Fmnl2,Pfkl,Ifit2,Parp8,B4galt4,Rgs14,Ets2,Cited2,Ptpn2,Fut8,Cish,Prdm1,Stxbp1,Lrp8,Prnp,Fam133b,Plagl1,1600014C10Rik,Ahr,Myo10 |
| 1.717e-06 | -13.27 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP | 187 | 35 | 15632 | 1249 |
Cd83,Sdc4,Samhd1,Atp11b,Etv5,Rhoh,Ppm1l,Sell,Gbp3,Ubash3b,Itgb8,Myc,Cish,Fcgr2b,Dusp4,Phlpp1,Rin2,Rapgef5,Tpst1,Swap70,Sec24a,Gfpt1,Rbms1,Frmd6,Gng12,Ppa1,Cpeb4,Larp1,Pim1,Tlr1,P4ha1,Eno2,Gbp7,Ptch1,Igsf8 |
| 1.717e-06 | -13.27 | GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_DN | MSigDB lists | GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_DN | 187 | 35 | 15632 | 1249 |
Lrp8,Trim13,Nlrp3,Slamf7,Hck,Rbl1,Lipe,Stat5a,Trim36,Agrn,B4galt4,Znfx1,Rbbp8,Stard5,Rab11fip1,Dhx58,Dck,Il13ra1,Rcan1,Ier3,Il18,Gfpt1,Gcnt2,Epsti1,Trafd1,Vrk2,Snx10,Arid4a,Slc12a9,Tnfsf14,Pdgfb,Inpp5b,H2-Aa,Usp12,Oas2 |
| 1.717e-06 | -13.27 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_DN | 187 | 35 | 15632 | 1249 |
Tpi1,Ccl22,Ciapin1,Socs1,Gmppb,Pigv,Cd83,Batf,Tap1,Tnf,Stat5a,Srm,Eno1,Cycs,Irf4,Gclm,Cish,Nqo1,Ebi3,Filip1l,Gng4,Cd200,Rcn1,Slc43a3,Tnip3,Ak4,Mthfd2,Ier3,Spata5l1,Ccl4,Txn1,Slc31a2,Cd86,Alas1,Eef1e1 |
| 1.717e-06 | -13.27 | GSE17721_POLYIC_VS_PAM3CSK4_6H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_6H_BMDC_UP | 195 | 36 | 15632 | 1249 |
Mcm10,Tmem176b,Rhoh,Ripk3,Pfkfb3,Rbms2,Tspo,Cutc,Crbn,Gadd45b,Aebp2,4932438A13Rik,Tbc1d1,1110038F14Rik,Edn1,Ppp2r5a,Ttc39b,Rnaset2b,Xcr1,Nfil3,Lrrc8c,Cldnd1,Tax1bp1,Ubr4,Klf2,Rnaset2a,Atp6v1d,Cep350,Ogfr,Rgl1,Slc7a8,S100a8,Ccl5,Etv6,Kctd12,Stxbp3 |
| 1.726e-06 | -13.27 | GO_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | 77 | 20 | 15632 | 1249 |
Nod2,Rapgef2,Sirt1,Nfkbid,Bcl6,Irf7,Il10,Cd274,Ccl5,Axl,Hcar2,Ripk3,Kitl,Hcls1,Irs2,Lyn,Nr4a3,Cd74,Hif1a,Fas |
| 1.727e-06 | -13.27 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | 357 | 55 | 15632 | 1249 |
Irak3,Usp18,Trim12c,Tnc,Cycs,D1Ertd622e,Cp,Mdm2,Cebpd,Bcl2a1d,Rsad2,Ifit2,Ddhd1,Tcf4,Bcl2a1a,Plat,Gng12,Pkp4,Fmnl2,Tfec,Cmpk2,Oas1g,Smc5,Ptgs2,Sap30,Wdfy1,H2-Aa,Nampt,Ifit1bl2,Gdf15,Sesn3,Cd274,Ppm1k,Il15,Enpp4,Tgs1,Samd9l,Pde5a,Trim36,Ifit1bl1,Slc7a11,Bcl2a1b,Spic,Rgs1,Prkar2b,Cpeb4,Etnk1,Dyrk2,Ifit3b,Mthfd2,Fabp7,Oas1a,Etv6,Xaf1,Ifit3 |
| 1.730e-06 | -13.27 | MARTENS_BOUND_BY_PML_RARA_FUSION | MSigDB lists | MARTENS_BOUND_BY_PML_RARA_FUSION | 393 | 59 | 15632 | 1249 |
Slc9a1,Ksr1,Flnb,Hivep3,Rap1gap2,Irf8,P2ry2,Plekha2,Tnfaip2,Cd82,Mmp9,Uaca,Irf1,Rcsd1,Acsl1,Lyn,Rab20,Kremen1,Plac8,Spn,Hivep2,Sqstm1,Hmga1,Atp2b4,Nek6,Ubash3b,Nlrp3,Gbe1,Ddit4,Gpr132,Slc7a5,Inhba,Vasp,Tyk2,Plek,Klf2,Lcp2,Fosb,Dusp28,Ptges,Ptprj,Hmox1,Dusp5,Zc3h12a,Cish,Rab11fip1,Itpr1,Rbbp8,Rhbdf2,Rnf34,Ccdc88b,Cd164,Hck,Tnfaip3,Itga4,Upp1,F11r,Icam1,Fgr |
| 1.739e-06 | -13.26 | BIOCARTA_TNFR2_PATHWAY | MSigDB lists | BIOCARTA_TNFR2_PATHWAY | 17 | 9 | 15632 | 1249 |
Traf2,Tank,Traf1,Nfkbia,Dusp1,Tnfrsf1b,Ikbkg,Nfkb1,Tnfaip3 |
| 1.739e-06 | -13.26 | SESTO_RESPONSE_TO_UV_C3 | MSigDB lists | SESTO_RESPONSE_TO_UV_C3 | 17 | 9 | 15632 | 1249 |
Ier3,Ptgs2,Brd2,Atf3,Dusp1,Il1b,Cycs,Myd88,Rnd3 |
| 1.739e-06 | -13.26 | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_UP | MSigDB lists | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_UP | 17 | 9 | 15632 | 1249 |
Nfil3,Frmd6,Rsad2,Ccdc86,Ak4,Serpine1,Junb,Rgl1,Socs3 |
| 1.774e-06 | -13.24 | TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | REACTOME pathways | R-MMU-975138 | 77 | 21 | 8608 | 757 |
Myd88,Tab2,Fos,Nfkb1,Tlr9,Ripk2,Map2k4,Ikbkg,Nod2,Jun,Dusp6,Dusp4,Nfkbib,Ppp2r1b,Nfkb2,Peli1,Nod1,Map3k8,Irak2,Nfkbia,Mapkapk2 |
| 1.775e-06 | -13.24 | T cell differentiation involved in immune response | biological process | GO:0002292 | 35 | 12 | 20694 | 1406 |
Il12b,Sema4a,Irf4,Batf,Stat3,Spn,Gadd45g,Clec4e,Clec4d,Relb,Il6,Ptger4 |
| 1.775e-06 | -13.24 | negative regulation of toll-like receptor signaling pathway | biological process | GO:0034122 | 35 | 12 | 20694 | 1406 |
Tlr6,Acod1,Nod2,Lyn,Tnfaip3,Trim30a,Tlr9,Nfkbil1,Irak3,Smpdl3b,Cd300lf,Irf4 |
| 1.775e-06 | -13.24 | positive regulation of interleukin-12 production | biological process | GO:0032735 | 35 | 12 | 20694 | 1406 |
Tnfsf9,Irf1,Tlr9,Il12b,Tnfsf4,Rel,Irf8,Tlr6,Cd40,Tlr3,Tlr2,Nod2 |
| 1.794e-06 | -13.23 | TRIF-mediated TLR3/TLR4 signaling | REACTOME pathways | R-MMU-937061 | 71 | 20 | 8608 | 757 |
Ripk2,Map2k4,Nfkb1,Nod2,Irf7,Ikbkg,Tab2,Myd88,Fos,Irak2,Map3k8,Nod1,Nfkb2,Mapkapk2,Nfkbia,Nfkbib,Dusp4,Dusp6,Jun,Ppp2r1b |
| 1.800e-06 | -13.23 | transcription regulatory region sequence-specific DNA binding | molecular function | GO:0000976 | 868 | 97 | 20217 | 1400 |
Hif1a,Batf2,Stat4,Ifi208,Ifi207,Hmga1,Pcgf5,Nfkb2,Batf,Pou2f2,Lhx2,Nfxl1,Zeb1,Mxd1,Fos,Nr4a3,Mycl,Dach1,Ifi214,Mafg,H3f3b,Aebp2,Bcl6,Jarid2,Jdp2,Arid5b,Plagl1,Zfp281,Tal2,Ifi209,Klf6,Klf3,Mndal,Foxp4,Irf2,Notch1,Atf3,Egr1,Kat2b,Ets2,Jun,Ifi213,Nfil3,Ifi204,Egr3,Klf7,Klf8,Junb,Nr3c1,Etv5,Hinfp,Irf4,Relb,Egr2,Rel,Ifi203,Spic,Ikzf1,Stat5a,Irf8,Hhex,Tcf4,Ifi205,Etv6,Prdm9,Sp140,Tfec,Bcor,Sirt1,Nlrc5,Nr1h3,Nr4a1,Max,Ier2,Pbx1,Nfkb1,Fosb,Mafk,Prdm1,Irf7,Lmo4,Hdac1,Ifi211,Cebpd,Kdm6b,Stat3,Maff,Rfx5,Myc,Zbtb5,Etv3,Stat1,Eno1,Stat2,Irf1,Hivep2,Ahr |
| 1.813e-06 | -13.22 | GO_REGULATION_OF_INTERFERON_BETA_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERFERON_BETA_PRODUCTION | 41 | 14 | 15632 | 1249 |
Zc3hav1,Relb,Ddx58,Irf1,Tlr2,Ifih1,Rnf135,Tlr3,Tlr9,Ripk2,Nmi,Rel,Irf7,Ifnar1 |
| 1.817e-06 | -13.22 | GO_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | MSigDB lists | GO_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | 126 | 27 | 15632 | 1249 |
Ptgs2,Zc3h12a,C3,Itga5,Hmox1,Mtdh,Il1b,Vegfc,Thbs1,Kdr,Pik3r6,Serpine1,Ccl5,Sirt1,Rapgef2,Pdgfb,Cysltr2,Sphk1,Cx3cl1,Il1a,Hif1a,Egr1,Cd34,Flt1,Cx3cr1,Acvrl1,Ccr3 |
| 1.817e-06 | -13.22 | regulation of macrophage migration | biological process | GO:1905521 | 41 | 13 | 20694 | 1406 |
Mtus1,Thbs1,Slamf8,Ccl2,Cmklr1,Stap1,Mmp14,P2ry12,Csf1,Cx3cl1,Ptprj,Ccl5,Cd200 |
| 1.837e-06 | -13.21 | response to reactive oxygen species | biological process | GO:0000302 | 164 | 29 | 20694 | 1406 |
Lcn2,Ppp1r15b,Prdx1,Thbs1,Src,Fos,Cflar,Jun,Sod2,Plk3,Il6,Traf2,Axl,Hp,Kdm6b,Bnip3,Sirt1,Mmp9,Pdgfrb,Nqo1,Tnfaip3,Nr4a3,Ripk3,Hmox1,Sphk1,Nox1,Itgav,Casp3,Prdx5 |
| 1.863e-06 | -13.19 | GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_UP | 164 | 32 | 15632 | 1249 |
Cd80,Sla,Cd38,Atp2b4,Mxd1,Plk3,Prdm1,Nupr1,Chst11,Fgl2,Gsr,Cpd,Spn,Cx3cr1,Swap70,Ttc39c,Osbpl3,Hcls1,Glrx,Endod1,Casp7,Ptprj,Serpinb9,Sap30,Smpdl3b,Hk2,Il18rap,Snx10,Myadm,Hopx,Itgal,Gem |
| 1.864e-06 | -13.19 | Traf6 (TNF receptor-associated factor 6) | protein interactions | 22034 | 100 | 26 | 7778 | 753 |
Sqstm1,Irf4,Tab2,Myd88,Ripk2,Hspa1b,Tlr3,Tnfaip3,Irak3,Syk,Rsad2,Cited2,Mapkbp1,Traf3ip2,Hspa2,Malt1,Trafd1,Cd40,Ikbkg,Tifa,Eno1,Tax1bp1,Irf7,Actb,Ppp1r15a,Zc3h12a |
| 1.864e-06 | -13.19 | TRIM5 | interpro domains | IPR032917 | 5 | 5 | 19984 | 1430 |
Trim30a,Trim30b,Trim30d,Trim12c,Trim12a |
| 1.874e-06 | -13.19 | GO_RESPONSE_TO_ALCOHOL | MSigDB lists | GO_RESPONSE_TO_ALCOHOL | 349 | 54 | 15632 | 1249 |
Il1b,Vcam1,Pim1,Ptgs2,Cxcl10,Ptafr,Inhba,Fzd1,Pdgfb,Klf2,Pdgfrb,Fosb,Junb,Ccl5,Cd38,Cd14,Icam1,Hif1a,Socs1,Errfi1,Ccnd1,Mecp2,Stat3,Casp3,Tnc,Rbbp8,Birc2,Dusp1,Klf6,Cdkn1a,Adrb2,Hmgcs1,C3,Socs3,Il10,Casp8,Ptch1,S100a8,Ccne1,Ahr,Il15,Tspo,Fas,Cdkn2d,Lrp8,Ifnb1,Nqo1,Edn1,Pla2g4a,Prkce,Il6,Fos,Ccl12,Ass1 |
| 1.911e-06 | -13.17 | GSE18893_TCONV_VS_TREG_2H_TNF_STIM_DN | MSigDB lists | GSE18893_TCONV_VS_TREG_2H_TNF_STIM_DN | 172 | 33 | 15632 | 1249 |
Phf11d,Thbs1,Trem1,Zhx2,Plek,Atm,Brd2,Cep350,Cnn3,Med13,Zfp36,Tlr1,H2-Q7,Etv3,Tulp3,Prnp,Nxf1,Nlrp3,Phf11a,Tnfrsf14,Phf11c,Phf11b,Klf3,Fam43a,Plac8,H2-Q4,Tet2,H2-Q6,Bcl6,Arhgap26,Ogfrl1,Cpd,I830077J02Rik |
| 1.911e-06 | -13.17 | GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP | MSigDB lists | GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP | 172 | 33 | 15632 | 1249 |
Hif1a,Pttg1,Isg15,Ifi214,Papss2,Ifih1,Ifi207,Myo10,Mdfic,Gbp2,Ifi213,Ccl12,Lrp4,Apobec3,Ifi205,Ifi209,Ccnd1,Mdm2,Pim2,Irf1,Ifi204,Jak2,Serpinb2,Psmb8,Mndal,Inpp5b,Ifi211,Isg20,Ifi208,Bst1,Ifi203,Xaf1,Pou2f2 |
| 1.911e-06 | -13.17 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_UP | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_UP | 172 | 33 | 15632 | 1249 |
Hcls1,Kitl,Rgs1,Etnk1,Mmp9,Filip1l,Lpar1,Clec5a,Hat1,Tnfsf14,Serpine1,Plau,Lpcat2,Samhd1,Me1,Hhex,Malt1,Ubash3b,Zfp281,Rnf135,Tbc1d1,Irgq,Spry2,Nat2,Dennd1b,Fgl2,Il18bp,Arhgap26,Errfi1,Chst11,Dock10,Txnrd1,Fos |
| 1.911e-06 | -13.17 | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_UP | MSigDB lists | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_UP | 172 | 33 | 15632 | 1249 |
Tnc,Fam43a,Trim36,Cst7,Bcl6,Rbms2,Pde3b,Clcn5,Hhex,Fas,Tlr6,Stxbp1,Cdk5r1,Ksr1,Isg20,Cysltr2,Rnf19a,Snx2,Mmd,Hap1,Egln3,Snx10,Jdp2,Samsn1,Rnaset2a,Lmo4,Casp4,Jak2,Rnaset2b,Gfi1,Hmox1,Kcna3,Cxcl10 |
| 1.940e-06 | -13.15 | GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | 180 | 34 | 15632 | 1249 |
Nr4a1,Ifit1bl1,Gramd1a,Dnaja1,Dusp2,Gbp9,Gbp4,Gadd45g,Kdm5b,Pml,Rtp4,Isg15,Ccnd2,Dusp14,Relb,Daxx,Ifit1,Sesn3,Tor3a,Ifit1bl2,Cep350,Irf7,Irf8,Phlda1,Spen,Trim21,Cnn3,Tdrd7,Spint2,Pcgf5,Dennd2a,Egr3,Ifi35,Parp11 |
| 1.940e-06 | -13.15 | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN | 180 | 34 | 15632 | 1249 |
Mcoln2,Pgs1,Trim12c,Adar,Traf5,Relb,Sod2,Bcl2l11,Ttc39c,Myc,Fchsd2,Slfn8,Taf4b,Parp3,Oas1g,Denr,Rnf19b,Rab20,Nr4a3,Tapbpl,Slfn9,Ikbke,Zcchc2,Igf2bp2,Sesn3,Pde4b,Casp4,Tor1aip1,Cnp,Zeb1,Spint2,Dgka,Etv6,Oas1a |
| 1.940e-06 | -13.15 | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | 180 | 34 | 15632 | 1249 |
Marcksl1,Ciita,Batf,Gypc,Src,Ezr,Jun,Arid5a,Mrpl52,Egr2,Dusp2,Dennd1b,Ikzf1,Irf4,Spry2,Filip1l,Cd55,Rnf19b,Mafg,Acsl1,Asb13,Spata5l1,Mcm6,Mthfd2,Slc43a3,Mob3b,Snapc1,Lnpep,Jarid2,Lmo4,Spen,Maff,Vasp,Slc39a14 |
| 1.940e-06 | -13.15 | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_DN | 180 | 34 | 15632 | 1249 |
Mdm2,Arhgap26,B4galt4,Msr1,Mtus1,Rapgef5,Spryd7,Cd34,Ubash3b,Pgm1,Stxbp1,Rhoh,Slc30a4,Marcksl1,Jag1,Slc25a12,Mmp13,Slc2a6,Trim21,Sap30,Itgal,Rnf14,Ednrb,Plek,Esd,Dcbld2,Il1rn,St7,Spire1,Rcan1,Itga5,Ptgir,Sema4c,Kpna3 |
| 1.944e-06 | -13.15 | inorganic ion homeostasis | biological process | GO:0098771 | 725 | 83 | 20694 | 1406 |
Cxcl2,Ccl5,Ccrl2,Edn1,Nox1,Cutc,Clic4,Cd40,Atp13a1,Ccr3,Ptgir,Ptk2,Slc4a7,Ednrb,Fpr1,Bnip3,Myc,Slc12a9,Htr2a,Mt2,Cx3cl1,Ccl3,P2ry2,Sod2,Cacna1d,Cxcl1,Kdr,Cmklr1,Ptger4,Atp2b4,Cp,Sco1,Cx3cr1,Ccr1,Mllt6,Pml,Gpr35,Rab20,Ccl2,Slamf8,Slc9a1,Slc30a1,Adrb2,Gpr18,Slc31a2,Hmox1,Prkce,Cav1,Cxcl3,Jak2,Slc39a4,Gja1,Itpr1,Htr2b,Itgav,Slc31a1,Slc30a4,Marcksl1,Il1b,Tmtc2,Slc39a14,Grina,Swap70,Gna15,Rmdn3,Lpar1,Mafg,Cxcl10,Hif1a,Ero1l,1600014C10Rik,Tmem178,Hap1,Fpr2,Lcn2,Snx10,Xcr1,Prnp,Slc39a13,Mt1,Cd38,Dmxl2,Cacnb3 |
| 1.946e-06 | -13.15 | adenyl nucleotide binding | molecular function | GO:0030554 | 1459 | 147 | 20217 | 1400 |
Tap1,Ass1,Trib3,Vrk2,Nod1,Oas2,Tyk2,Atp10a,Helz2,Kdr,Ripk2,Etnk1,Clcn5,Clcn7,Myo10,Cgas,Irak2,Ehd1,Ube2l6,Ciita,Ascc3,Irak3,Ak4,Oasl2,Abcc5,Mthfd1l,Acvr1,Hspa1b,Prkar2b,Tlk2,Ube2e1,Akt3,Scyl2,Nlrp3,Map4k4,Pfkl,Acvrl1,Pdk3,Map3k6,Pim1,Sphk1,Ddx58,Ikbke,Plk3,Stk40,Prag1,Smc5,Myo1b,Nlrc4,Pgk1,Flt1,Slfn5,Slfn9,Papss2,Ube2f,Map2k1,Hk3,Hspa1a,Tor3a,Map3k8,Hk2,Pcx,Nek6,Dnaja1,Mlkl,Katna1,Dgka,Nlrc5,Pde4b,Plk2,Atp13a1,Dnaja2,Sik3,Ep400,Atp11a,Abcc1,Ube2e2,Lyn,Prkce,Abcb1a,Ddx4,Trip13,Oasl1,Chd9,Nod2,Actb,Srxn1,Itpkc,Oas3,Ksr1,Pikfyve,Cmpk2,Cenpe,Apaf1,Trib1,Gclc,Dyrk2,Grk3,Ptk2,Tent4a,Atp2b4,Pim3,Wars,Mark2,Kif9,Acvr1b,Sgk3,Pim2,Kif3c,P2ry2,Syk,Igf1r,Ripk3,Slfn8,Prkx,Fam20c,Mapkapk2,Mov10,Pdgfrb,Acsl5,Hspa2,Eif2ak2,Src,Ifih1,Gk,Mcm6,Dck,Dync1h1,Axl,Hk1,Fgr,Pgs1,Rars,Map2k4,Met,Jak2,Asns,Dhx58,Mcm9,Swap70,Tent2,Acsl1,Hck,Atm,Tap2,Hsph1,Pik3cd |
| 1.951e-06 | -13.15 | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP | 188 | 35 | 15632 | 1249 |
Phlda1,Procr,Isg20,Tmem176a,Rnf19a,Ccl5,Ptch1,Cep350,Gem,Cav1,Thbs1,Kitl,Cmpk2,Il15ra,Plaur,Pcgf5,Ptprj,Cacnb3,Odc1,Rcan1,C1ra,Errfi1,Glipr2,Tagln,Nr4a1,Klf6,Dnaja1,Adar,Prdx1,Olr1,Col18a1,Stxbp1,Evl,Prnp,F11r |
| 1.954e-06 | -13.15 | lymphocyte migration | biological process | GO:0072676 | 54 | 15 | 20694 | 1406 |
Cxcl10,Ccl4,Crkl,Ccl5,Cx3cl1,Icam1,Ccl3,Ccl7,Ccl2,Ccl8,Itga4,Ccl22,Ch25h,Ccl9,Ccl12 |
| 1.979e-06 | -13.13 | BIOCARTA_LYM_PATHWAY | MSigDB lists | BIOCARTA_LYM_PATHWAY | 10 | 7 | 15632 | 1249 |
Cd34,Vcam1,Itga4,Sell,Itgal,Icam1,Il1a |
| 1.979e-06 | -13.13 | BAKER_HEMATOPOESIS_STAT1_TARGETS | MSigDB lists | BAKER_HEMATOPOESIS_STAT1_TARGETS | 10 | 7 | 15632 | 1249 |
Casp7,Mmp9,Casp1,Casp2,Ciita,Casp3,Myc |
| 1.980e-06 | -13.13 | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | 112 | 25 | 15632 | 1249 |
Casp3,Il6,Timp1,Jun,Tank,Casp1,Apaf1,Myd88,Bmp2,Il1a,Fas,Fzd1,Btg2,Cav1,Pdgfrb,Gja1,Ccne1,Plaur,Cdkn1a,Cflar,Plat,Idi1,Egr3,Casp7,Tlr3 |
| 1.980e-06 | -13.13 | MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | MSigDB lists | MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | 112 | 25 | 15632 | 1249 |
Il1rn,Slfn3,Ikbke,Glrx,Ifi35,Tapbpl,Serpinb9,Trim21,Ampd3,Wars,Inhba,Tmem176a,Il18rap,Xaf1,Ifit1bl2,Snx10,Slfn4,Pdgfrb,Casp4,Tnfrsf14,Tnks1bp1,Tmem176b,Cp,Ifit1bl1,Ccl12 |
| 1.984e-06 | -13.13 | GO_REGULATION_OF_BINDING | MSigDB lists | GO_REGULATION_OF_BINDING | 271 | 45 | 15632 | 1249 |
Csf3,Rapgef2,Ifi208,Pdgfb,Hopx,Plk2,Txn1,Ifit1bl2,Plaur,Bambi,Mitd1,Plcl2,Trib3,Hmox1,Ifi205,Ifi209,Eno1,Traf2,Ifi213,Ifit2,Src,Bmp2,Lif,Itga4,Ifi203,Slpi,Ifi211,Mndal,Il10,Cav1,Lhx2,Jak2,Adrb2,Aida,Ifi204,Mmp9,Irf4,Jun,Nfkbia,Crbn,Ifit1bl1,Angpt1,Ifi207,Ifi214,Kat2b |
| 1.984e-06 | -13.13 | GO_REGULATION_OF_PROTEIN_TARGETING | MSigDB lists | GO_REGULATION_OF_PROTEIN_TARGETING | 271 | 45 | 15632 | 1249 |
Keap1,Il1b,Bambi,Il12b,Il18,Ptgs2,Zc3h12a,Tlr3,Fzd1,G3bp2,Csf3,Fzd5,Txn1,Mdfic,Plagl2,Sphk1,Ddx58,Parp10,Nfkbil1,Rbpms,Nfkbie,Micall2,Tnf,Cdkn1a,Stard7,Hcls1,Jak2,Tlr2,Dyrk2,Tlr9,Rhou,Sirt1,Nfkbib,Slc9a1,Il10,Tnfsf14,Rnf31,Angpt1,Prdx1,Cdk5r1,Nlrp3,Il6,Psmd10,Ccl12,Nfkbia |
| 2.036e-06 | -13.10 | NOJIMA_SFRP2_TARGETS_UP | MSigDB lists | NOJIMA_SFRP2_TARGETS_UP | 26 | 11 | 15632 | 1249 |
Ppp1r15a,Jun,Cd40,Gadd45b,Ikbkg,Wars,Csf1,Trib3,Nr4a3,Mxd1,Tnfaip3 |
| 2.036e-06 | -13.10 | BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | 26 | 11 | 15632 | 1249 |
Ccnd2,Rab20,Irs2,Klf6,Slc7a11,Klf7,Cd69,Egln3,Sat1,Rras2,Rgs1 |
| 2.036e-06 | -13.10 | BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN | 26 | 11 | 15632 | 1249 |
Ptger4,Thbs1,Tagln,Dusp6,Serpine1,Tnc,Irgm2,Myc,Ly75,Errfi1,Inhba |
| 2.055e-06 | -13.10 | GO_NEGATIVE_REGULATION_OF_CYTOKINE_SECRETION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYTOKINE_SECRETION | 36 | 13 | 15632 | 1249 |
Zc3h12a,Pml,Ptger4,Tnfsf4,Cx3cl1,Nlrp3,Cd34,Angpt1,Rabgef1,Ezr,Tnf,Il10,Il6 |
| 2.055e-06 | -13.10 | DORN_ADENOVIRUS_INFECTION_48HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_48HR_DN | 36 | 13 | 15632 | 1249 |
Il6,Ccnd1,Txnrd1,Nfkbia,Junb,Nr4a1,Fubp1,Plk2,Cd83,Rnd3,Ell2,Egr3,Ier3 |
| 2.066e-06 | -13.09 | cell cycle G1/S phase transition | biological process | GO:0044843 | 68 | 17 | 20694 | 1406 |
Hinfp,Acvr1,Pim2,Cdkn1a,Ccne1,Rbbp8,Plk2,Gpr132,Rhou,Plk3,Ccnd1,Rgcc,Crlf3,Inhba,Cdkn2d,Ccnd2,Acvr1b |
| 2.069e-06 | -13.09 | HALMOS_CEBPA_TARGETS_UP | MSigDB lists | HALMOS_CEBPA_TARGETS_UP | 47 | 15 | 15632 | 1249 |
Nfil3,Glrx,Bmp2,Jak2,Cxcl1,Arl4a,Slc30a1,Il4ra,Ptgs2,Hmox1,Fas,Cxcl2,Ets2,Sema3c,Rab32 |
| 2.069e-06 | -13.09 | TAVOR_CEBPA_TARGETS_UP | MSigDB lists | TAVOR_CEBPA_TARGETS_UP | 47 | 15 | 15632 | 1249 |
Tank,Sod2,Bcl2a1b,Gch1,Bcl2a1d,Spint2,Btg2,Trib1,Ccnd2,Acsl1,Hmox1,Nfil3,Extl2,Il1rn,Bcl2a1a |
| 2.074e-06 | -13.09 | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | MSigDB lists | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | 65 | 18 | 15632 | 1249 |
Il4ra,Odc1,Dck,Col18a1,Rbl1,Col4a2,Jun,Serpine1,Timp1,Ccl12,Gadd45b,Inhba,Ly75,Tnc,Csf1,Pla2g4a,Edn1,Irgm2 |
| 2.075e-06 | -13.09 | cellular response to organic cyclic compound | biological process | GO:0071407 | 451 | 58 | 20694 | 1406 |
Nos2,Mul1,Pdgfb,Bmp2,Stat3,Src,Rapgef2,Nr3c1,Pim1,Ddx58,Ahr,Nr4a3,Inhba,Cav1,Nfkb1,Acod1,Ptch1,Itpr1,Htr2b,Stat1,Jak2,Casp3,Tlr3,Il1b,Zc3hav1,Gramd1a,Zc3h12a,Il18,Tiparp,Tnf,Socs1,Daxx,P2ry12,Stat5a,Mecp2,Atp2b4,Nr4a1,Ddit4,Ccl12,Glrx,Ezr,Slc9a1,Nfkbia,Tlr9,Ccl5,Egr1,Slc16a1,Ifnb1,Larp1,Dnaja1,Ifih1,Cgas,Nr1h3,Casp7,P2ry13,Actb,Zfp36,Pde4b |
| 2.083e-06 | -13.08 | positive regulation of T cell proliferation | biological process | GO:0042102 | 98 | 21 | 20694 | 1406 |
Ccdc88b,Il12b,Il1b,Cd86,Cd274,Tnfsf4,Nck1,Spn,Itgal,Tnfsf9,Il18,Icosl,Ripk2,Il12rb1,Stat5a,Ccl5,Il15,Il6,Syk,Cd80,Vcam1 |
| 2.083e-06 | -13.08 | negative regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001237 | 98 | 21 | 20694 | 1406 |
Serpine1,Tnfaip3,Rffl,Cflar,Cx3cl1,Tnf,Icam1,Hmox1,Rnf34,Itgav,Phip,Cx3cr1,Sgk3,Il1b,Eya4,Acvr1,Tnfsf4,Gclc,Gclm,Pf4,Src |
| 2.122e-06 | -13.06 | kinase activity | molecular function | GO:0016301 | 758 | 87 | 20217 | 1400 |
Pikfyve,Cmpk2,Ksr1,Itpkc,Pim3,Trib1,Ccnd1,Grk3,Ptk2,Dyrk2,Prkce,Lyn,Nrp2,Dgka,Sik3,Plk2,Ccnj,Pik3r6,Met,Map2k4,Jak2,Dck,Hk1,Fgr,Axl,Cdk5r1,Atm,Hck,Pik3cd,Dgkh,Pim2,Cdkn1a,Sgk3,Acvr1b,Mark2,Eif2ak2,Src,Gk,Sla,Syk,Igf1r,Ripk3,Pdgfrb,Fam20c,Prkx,Mapkapk2,Irak2,Ciita,Tlk2,Pfkfb3,Scyl2,Akt3,Ak4,Irak3,Acvr1,Tyk2,Kdr,Ccne1,Trib3,Mmd,Vrk2,Etnk1,Ripk2,Hk3,Map2k1,Ccng2,Ccnd2,Papss2,Nek6,Sgms2,Mlkl,Ccl5,Hk2,Map3k8,Sphk1,Map3k6,Pim1,Ikbke,Map4k4,Pdk3,Acvrl1,Pfkl,Pgk1,Flt1,Plk3,Prag1,Stk40 |
| 2.134e-06 | -13.06 | GO_TISSUE_DEVELOPMENT | MSigDB lists | GO_TISSUE_DEVELOPMENT | 1389 | 158 | 15632 | 1249 |
Nr4a3,Arid5b,Kitl,Htr2b,Pgk1,Myadm,Gja1,Col11a2,Fzd5,Pdgfrb,Map2k1,Nrp2,Sap30,Ext1,Rab10,Mmp13,Rapgef2,Inhba,Ppp2r3a,Vasp,Fzd1,Prdm1,Nupr1,Slc39a13,Tulp3,F11r,Arg2,Sav1,Pbx1,Apaf1,Plod3,Txnrd1,Homer1,Phgdh,Tnc,Itgb8,Errfi1,Hdac1,Sema4c,Itga5,Mmp9,Rpgrip1l,Notch2,Jak2,Rap2c,Col27a1,Lhx2,Cdkn1a,Frmd6,Atm,Ednrb,Sema3c,Cav1,Lmo4,Csf1,Zeb1,Slc9a1,Cnn3,Tdrd7,Palld,Col18a1,Sdc1,Sdc4,Cd34,Col4a2,Sgcb,Dhrs9,Itgav,Cited2,Ets2,Pla2g4a,Dusp2,Mmp14,Ifrd1,Phactr4,Ift57,Dusp4,Kdm6b,Dusp5,Fndc3a,Ptgs2,Tgfbi,Clic4,Prkx,Vegfc,Sec24b,Slc4a7,Nampt,Junb,Arid4a,Mthfd1l,Klf2,Igsf8,Pdgfb,Btg2,Rilpl1,Maff,Itga4,Hhex,Hlx,Pml,Lif,Hif1a,Icam1,Intu,Bmp2,Notch1,Hck,Rhoc,Dusp1,Src,Lrp4,Timp1,Gpsm2,Casp3,Minpp1,Setdb2,Egr2,Acvr1,Ccnd1,Kdm5b,Mdm2,Acvrl1,Stat1,Socs3,Acvr1b,Sema4a,Cflar,Fam20c,Kdr,Clic5,Il10,Ptch1,Bcl9,Timeless,Flnb,Hivep3,Jag1,Met,Atf3,Egr1,Plagl1,Plau,Slc25a25,Ezr,Slc7a11,Flrt3,Tagln,Sbds,Fos,Jun,Tiparp,Spry2,Edn1,Ikzf1,Il6,Myc,Chst11 |
| 2.137e-06 | -13.06 | GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN | MSigDB lists | GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN | 165 | 32 | 15632 | 1249 |
Etv3,Upp1,Ddx60,Tmem176b,Malt1,Klf7,Ripk3,Myo10,Herc3,Rras2,Pde3b,Acpp,B4galt4,Cd302,Parp8,Treml2,Aebp2,Taf4b,Rab11fip1,Smox,Kif5c,Itga5,Socs3,Tagap,Zhx2,Znrf1,Zc3h12c,Slc7a8,Card6,Tmem176a,Cysltr2,Btg2 |
| 2.148e-06 | -13.05 | MAP kinase phosphatase activity | molecular function | GO:0033549 | 15 | 8 | 20217 | 1400 |
Dusp5,Dusp16,Dusp8,Dusp2,Dusp6,Dusp4,Dusp14,Dusp1 |
| 2.163e-06 | -13.04 | BIOCARTA_DEATH_PATHWAY | MSigDB lists | BIOCARTA_DEATH_PATHWAY | 31 | 12 | 15632 | 1249 |
Birc2,Casp8,Traf2,Nfkb1,Birc3,Nfkbia,Cycs,Casp3,Casp7,Apaf1,Tnfsf10,Cflar |
| 2.163e-06 | -13.04 | GO_CYTOKINE_SECRETION | MSigDB lists | GO_CYTOKINE_SECRETION | 31 | 12 | 15632 | 1249 |
Nlrp3,Nos2,Lyn,Tlr2,Nlrc4,Lcp2,Tlr6,Aim2,Nod2,Notch1,Trem1,Pnp2 |
| 2.163e-06 | -13.04 | BIOCARTA_IL1R_PATHWAY | MSigDB lists | BIOCARTA_IL1R_PATHWAY | 31 | 12 | 15632 | 1249 |
Ifnb1,Il6,Jun,Tnf,Nfkbia,Nfkb1,Irak3,Il1b,Il1rn,Myd88,Irak2,Il1a |
| 2.172e-06 | -13.04 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP | 59 | 17 | 15632 | 1249 |
Ifi213,Ifi209,Mndal,Ifi205,Ifi208,Ifi211,Ifi203,Tmem176a,Cd200,Tmem176b,Ifi214,Arid5b,Ifi204,Fscn1,Angpt1,Snn,Ifi207 |
| 2.181e-06 | -13.04 | BURTON_ADIPOGENESIS_PEAK_AT_16HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_16HR | 53 | 16 | 15632 | 1249 |
Mndal,Ifi209,Hmga1,Ifi205,Ass1,Ifi213,Hat1,Ifi203,Vcan,Ifi208,Ifi211,Ifi214,Fam111a,Mcm6,Ifi204,Ifi207 |
| 2.184e-06 | -13.03 | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN | 173 | 33 | 15632 | 1249 |
St3gal5,Lmo4,Cnp,Daam1,Samsn1,Tnfrsf1b,Tor3a,Plek,Tfec,Abcc4,Cldnd1,Ralgds,Cd82,Ppa1,Socs3,Dock10,Optn,Slc15a3,Dusp2,Fut8,Ctsc,Cycs,Sp140,Ehd1,Eif2ak2,Tle3,Mvp,Mdfic,Gng11,Rnf34,Ccnd2,Tpi1,Aim2 |
| 2.184e-06 | -13.03 | Ig-like_dom_sf | interpro domains | IPR036179 | 501 | 65 | 19984 | 1430 |
Cd300lf,Cd274,Pvr,H2-Ab1,Cd83,Pilrb1,Slamf7,Vcam1,Cd200,A530064D06Rik,Pilrb2,H2-Eb1,Tapbpl,Treml4,H2-Q4,Il12b,Icam1,Mfap3l,Vcan,Csf3r,Treml2,H2-Aa,Il18bp,Nectin2,Spaca6,Pilra,Igsf8,Milr1,Siglece,H2-T10,Sema4c,Pdgfrb,Icosl,Slamf8,Flt1,Igsf6,Gm5150,Palld,Fcgr2b,Fcgr1,Igsf9,Tarm1,Cd200r4,Sema3c,Nectin4,Clmp,H2-T24,Cd300e,H2-T22,B430306N03Rik,Slamf9,Fcgr4,F11r,Scn1b,Malt1,Cd86,Axl,Cd80,Trem1,H2-Q7,H2-Q6,H2-M2,Kdr,Il18rap,Tapbp |
| 2.209e-06 | -13.02 | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_UP | 181 | 34 | 15632 | 1249 |
Slc39a4,D1Ertd622e,Abcb1a,Samd9l,Nfkbie,Agrn,Nlrc5,D16Ertd472e,Cd40,Plau,Tnks1bp1,Tmem176b,Ddx60,Hhex,Irs2,Ppm1l,Ccl22,Etv3,Piezo1,Gpr132,Trim26,Kctd12,Pou2f2,Tuba4a,Junb,Nampt,Klf2,Gca,Cacna1d,Lrrc8c,Dnajb2,Filip1l,Stat1,Socs3 |
| 2.209e-06 | -13.02 | GSE27786_LIN_NEG_VS_MONO_MAC_DN | MSigDB lists | GSE27786_LIN_NEG_VS_MONO_MAC_DN | 181 | 34 | 15632 | 1249 |
Rtp4,Ddx58,Aim2,Nck1,Zc3hav1,Tnks1bp1,Mark2,Ccdc88b,Cited2,Cyfip1,N4bp1,Axl,Ehd1,Ezr,Trim36,Triobp,Mdm2,Ogfrl1,Fgl2,Il18bp,Gpr35,Fcgr2b,Nr3c1,Map3k8,Clec5a,Rac3,Fmnl2,Slc37a3,Card6,Ppp1r15b,Myadm,Cxcl2,Usp12,Tlr1 |
| 2.209e-06 | -13.02 | GSE17721_LPS_VS_POLYIC_6H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_6H_BMDC_UP | 181 | 34 | 15632 | 1249 |
Hinfp,F10,Sgcb,Fpr2,Ccl22,Fam133b,Calcrl,Cish,Ccl2,Gsr,Prdx5,Clmp,Gadd45b,Aoah,Acsl5,Sh3bgrl2,Nlgn2,Lrrc8c,Pmepa1,Abcc1,Stip1,Kif5c,Tnfsf4,Clec4d,Rab20,Rnf145,Cysltr2,Akt3,Vasp,Tnfrsf1b,Tshz1,Dach1,Slc7a2,Il10 |
| 2.209e-06 | -13.02 | GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDC_UP | 181 | 34 | 15632 | 1249 |
Wars,Rhou,Hat1,Ext1,Pdss1,Mov10,Atp6v1d,Casp4,Slc12a9,Psmb8,Ccnj,Slc7a8,Tor3a,Dusp6,Ccl5,Vrk2,Gtpbp2,Plcl2,Clec5a,Pik3cd,Glipr2,4932438A13Rik,Ikzf1,Rab9,Tnfsf8,Ptpn2,Klf6,Spn,Psip1,Chmp4b,Gbp2,Sgk3,Prnp,Mcm10 |
| 2.209e-06 | -13.02 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP | 181 | 34 | 15632 | 1249 |
Znrf1,Ldlr,Ikbke,Plaur,Rnaset2b,Igf1r,Dck,Kcna3,Gpd2,Cnn3,Isg20,Ext1,Ddit4,Dcp1a,Birc3,Jarid2,Rnf14,P4ha1,Dusp6,Rnaset2a,Ifit1,Rab3ip,Slc30a4,Tlr6,Cyth3,Zfp281,Slc44a1,Egr2,Hdac1,Spsb1,Srm,Birc2,Tcf4,Ets2 |
| 2.214e-06 | -13.02 | GSE360_CTRL_VS_M_TUBERCULOSIS_MAC_DN | MSigDB lists | GSE360_CTRL_VS_M_TUBERCULOSIS_MAC_DN | 189 | 35 | 15632 | 1249 |
Trib1,Dnajb4,Acsl1,Stat1,Dr1,Il1rn,Bcl2a1a,Serpine1,Slc31a2,Ednrb,Rap1gap2,Reps1,Inpp5b,Sap30,Ifih1,Nxf1,Aim2,Slc30a4,Stau1,Irak3,Gbp2,Mapkbp1,Rras2,Tcf4,Trip10,Ptpn2,Gadd45b,Bcl2a1b,Ifrd1,Optn,Rsad2,Bcl2a1d,Dtnb,Cers6,Pnp2 |
| 2.214e-06 | -13.02 | GSE17721_CTRL_VS_CPG_1H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_1H_BMDC_DN | 189 | 35 | 15632 | 1249 |
Ccrl2,Gja1,Plk2,Samsn1,Sema3c,Inpp1,Il1rn,Dnajb2,Cdkn1a,Dnaja2,Ebi3,Map3k8,Arid5b,Serpinb9,Ptafr,Ier3,Mthfd2,Cxcl10,Adrb2,Chic2,Dnajb4,Oaf,Ift57,Dtnb,Mdm2,Lztfl1,Spryd7,Phldb1,Ttc39c,Cd14,Slc25a25,Usp25,Fas,Ier2,Etv3 |
| 2.214e-06 | -13.02 | GSE2826_WT_VS_XID_BCELL_UP | MSigDB lists | GSE2826_WT_VS_XID_BCELL_UP | 189 | 35 | 15632 | 1249 |
Bcl2a1d,Hspa2,Hdac1,Il4i1,Bcl2a1b,Casp1,Dync1h1,Hivep2,Klf7,Cd38,Cd83,Isg15,Il4ra,St3gal6,Cx3cl1,Fabp3,Ccl22,Tpi1,Mcoln2,Marcksl1,Dgka,Snx2,Plscr1,Pdgfrb,Ccr1,Bcl2a1a,Il2rg,Nr4a3,Ms4a6d,Ppa1,Cd200,Casp7,Ebi3,Etnk1,Ptprj |
| 2.233e-06 | -13.01 | other organism part | cellular component | GO:0044217 | 30 | 11 | 20747 | 1409 |
Gbp7,Irgm2,Gbp2,Gbp2b,Gbp9,Gbp3,Axl,Pf4,Sco1,Gbp8,Iigp1 |
| 2.233e-06 | -13.01 | other organism cell | cellular component | GO:0044216 | 30 | 11 | 20747 | 1409 |
Gbp9,Irgm2,Gbp2b,Gbp2,Gbp7,Iigp1,Sco1,Gbp8,Pf4,Axl,Gbp3 |
| 2.249e-06 | -13.00 | endocytosis | biological process | GO:0006897 | 348 | 48 | 20694 | 1406 |
Lrp4,Reps1,Fpr2,Snx10,Ldlr,Ly75,4932438A13Rik,Thbs1,Treml4,Grk3,Cav1,Clcn5,Dbnl,Rin2,Htr2b,Lrp11,Marco,Trip10,Mapkapk2,Scarf1,Fcho2,Fchsd2,Ehd1,Rhou,Snx2,Sh3bp4,Syk,Ezr,Scyl2,Fcgr2b,Xkr8,Fcgr1,Fnbp1l,Adrb2,Rab20,Carmil1,Calcrl,Jmjd6,Dennd1b,Lrp8,Rabgef1,Nlgn2,Msr1,Rhoq,Rac3,Itga4,Actb,Cd14 |
| 2.279e-06 | -12.99 | GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 150 | 30 | 15632 | 1249 |
Tagap,Socs7,Bambi,Sec24a,Prkx,Osgin2,Ptgs2,Slc43a3,Odc1,Map3k8,Smox,Hivep3,Cd274,Rel,Fzd5,Med21,Batf,Extl2,Ahsa1,Clec4e,Plk3,Prrg4,Taf4b,Psd,Otud1,Fos,Gpsm2,Trip10,Klf6,Zswim4 |
| 2.324e-06 | -12.97 | GO_CELL_CELL_ADHESION | MSigDB lists | GO_CELL_CELL_ADHESION | 565 | 77 | 15632 | 1249 |
Src,Tnf,Ifnar1,P2ry12,Tnfsf8,Treml2,Sele,Rsad2,Malt1,Itga4,Rhoh,Icam1,Cd74,Jmjd6,Psmb10,Batf,Ripk3,Cd164,Ifna2,Relb,Plek,Igsf9,Csrp1,Ccl5,Fzd5,Cd86,Icosl,Stxbp3,Ifna6,Ptger4,Ripk2,Fndc3a,Clec4d,Il12b,Vcam1,Pcdh7,Pkp4,Il1b,Spn,Ezr,Slc7a11,Flrt3,Syk,Itgav,Ptpn2,Irf4,Il6,Pdpn,Ifna5,Ifnb1,Nck1,Fas,Stxbp1,Egr1,Cdk5r1,Il15,Cd34,Ifna1,Clec4e,Cd80,Olr1,S100a8,Itgal,Vezt,Tnfsf14,Casp8,Tnfsf4,Ebi3,Cd200,Itga5,Irf1,Sema4a,Azi2,Pik3cd,Actb,Tnip1,Nlgn2 |
| 2.326e-06 | -12.97 | Antigen processing and presentation | KEGG pathways | ko04612 | 89 | 23 | 7931 | 713 |
H2-M2,H2-Q6,Rfx5,H2-Aa,Tnf,H2-T10,Psme2,Hspa1b,Psme1,Tap1,Cd74,H2-Q7,H2-T24,Hspa1a,Psme2b,H2-Ab1,Ciita,Hspa2,H2-Eb1,H2-T22,Tap2,H2-Q4,Tapbp |
| 2.326e-06 | -12.97 | Antigen processing and presentation | KEGG pathways | mmu04612 | 89 | 23 | 7931 | 713 |
Cd74,H2-Q4,Tapbp,Tap2,Tap1,H2-T22,Psme1,Hspa1b,Tnf,H2-Eb1,Psme2,H2-T10,H2-Ab1,Hspa1a,Psme2b,Ciita,Hspa2,H2-T24,Rfx5,H2-Aa,H2-Q7,H2-Q6,H2-M2 |
| 2.378e-06 | -12.95 | GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN | MSigDB lists | GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN | 158 | 31 | 15632 | 1249 |
Tnfrsf14,Tnfaip3,Pde3b,Dmxl2,Nlrp3,Ube2e1,Tra2a,Ogfrl1,Rab21,Abcb1a,Peli1,Otud1,Tet2,Bcl6,Klf3,Dusp1,Plaur,Thbs1,Fcho2,Arid5b,Sirt1,AA467197,Akt3,Atxn7l1,Med13,Zfp36,Zc3h12c,Sik3,Cep350,Dach1,Nampt |
| 2.418e-06 | -12.93 | Pept_C14A | interpro domains | IPR015917 | 11 | 7 | 19984 | 1430 |
Casp4,Casp2,Casp3,Cflar,Casp1,Casp8,Casp7 |
| 2.418e-06 | -12.93 | GBP_C | interpro domains | IPR037684 | 11 | 7 | 19984 | 1430 |
Gbp9,Gbp2,Gbp3,Gbp2b,Gbp4,Gbp7,Gbp8 |
| 2.418e-06 | -12.93 | Chemokine_CXC | interpro domains | IPR001089 | 11 | 7 | 19984 | 1430 |
Pf4,Cxcl1,Cxcl2,Cxcl3,Cxcl10,Cxcl9,Cxcl11 |
| 2.461e-06 | -12.92 | cellular response to endogenous stimulus | biological process | GO:0071495 | 1020 | 108 | 20694 | 1406 |
Trib3,Sirt1,Pdgfc,Mdm2,Prkce,Cdk5r1,Nr4a3,Ahr,Nfkb1,Cav1,Casp3,Acod1,Itpr1,Htr2b,Bmp2,Prnp,Nmral1,Cpeb4,Rapgef2,Timeless,Fos,Acsl1,Acvr1b,Cyfip1,Junb,Actb,Gdf15,Pde4b,Icam1,Egr1,Rab10,Nod1,Ifnb1,Irs2,Kat2b,Vcam1,Phip,Larp1,Fut8,Igf1r,Fcgr2b,Pml,Zyx,Col4a2,Acvrl1,Agtrap,Daxx,Tnf,Jun,P2ry12,Bambi,Pde3b,Cited2,Sh3bp4,Nlrp3,Notch1,Pid1,Akt3,Il18,Tlr2,Inhba,Flrt3,Tlr6,Jak2,Stat1,Crkl,Fpr2,Src,Stat3,Gcnt2,Egr3,Nr3c1,Casp4,Sesn3,Ripk2,Casp7,Nr1h3,Zeb1,Ptk2,Zfp36,Ptpn2,Pdgfrb,Dcp1a,Itga4,Flrt2,Nod2,Serpine1,Rhoq,Dnaja1,Socs7,Glrx,Tnfsf4,Acvr1,Ddit4,Nr4a1,Ezr,Ccl2,Irf1,Adrb2,Apaf1,Tlr9,Slc9a1,Socs1,Stat5a,Ehd1,Ptger4,Atp2b4,Mecp2 |
| 2.469e-06 | -12.91 | negative regulation of alpha-beta T cell activation | biological process | GO:0046636 | 42 | 13 | 20694 | 1406 |
Arg2,Tnfrsf14,Hlx,Tarm1,Il4ra,Socs1,Adora2a,Bcl6,Zc3h12a,Irf1,Lgals9,Cd274,Tnfsf4 |
| 2.476e-06 | -12.91 | positive regulation of receptor signaling pathway via JAK-STAT | biological process | GO:0046427 | 99 | 21 | 20694 | 1406 |
Hdac1,Il18,Parp14,Il10,Notch1,Hcls1,Il12b,Cd40,Ptger4,Lif,Il6,Cenpj,Jak2,Osm,Parp9,Crlf3,Lyn,Il15,Clcf1,Tnf,Ccl5 |
| 2.476e-06 | -12.91 | negative regulation of cysteine-type endopeptidase activity | biological process | GO:2000117 | 99 | 21 | 20694 | 1406 |
Nr4a1,Plaur,Birc3,Cst7,Mmp9,Src,Hspa1b,Thbs1,Mdm2,Adora2a,Ptgs2,Tnfsf14,Serpinb9,Cflar,Cdkn2d,Bcl2a1d,Rffl,Birc2,Rnf34,Prdx5,Il6 |
| 2.493e-06 | -12.90 | GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_DN | MSigDB lists | GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_DN | 174 | 33 | 15632 | 1249 |
Isg15,Nfkbil1,Dnase1l3,Cd38,Mapkbp1,Cited2,Swap70,Cst7,Ass1,Hsph1,Dtnb,Dusp8,Tnfsf8,Rcn1,Il13ra1,Ptprj,Tnfsf10,Kitl,Tmem123,Ptch1,Lmo4,P2ry2,Serpine1,Casp4,Irf8,Atm,Abtb2,Ppp2r3a,Stx11,Jag1,Pla2g7,Nmi,Pdlim7 |
| 2.493e-06 | -12.90 | GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN | MSigDB lists | GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN | 174 | 33 | 15632 | 1249 |
Rsad2,Tnf,Stat5a,Fam43a,Nfkbia,Srm,Gpr18,Mtus1,Zyx,Ahr,Hck,Mdfic,Hhex,Ddx60,Usp18,P2ry14,Oas1a,Xaf1,AA467197,Pde4b,Map4k4,Tuba4a,Ifit3,Rims3,Irf7,Ralgds,Lrrc8c,St3gal1,Denr,Oas1g,Tgfbi,Frmd4a,Ifit3b |
| 2.497e-06 | -12.90 | GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 143 | 29 | 15632 | 1249 |
P2ry2,Nos2,Ednrb,Ccl5,Ifit1bl2,Inhba,Trim21,Ptafr,Acvr1b,Ripk2,Larp1,Polr2g,Jun,Ankrd17,Bcl2l11,Ifit1bl1,Pcx,Pde5a,Dhx58,Cd180,Ddx60,Zc3hav1,Mdfic,Notch1,Chmp4b,Stau1,Adar,Plau,Nod1 |
| 2.510e-06 | -12.90 | GSE30083_SP1_VS_SP2_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP2_THYMOCYTE_DN | 190 | 35 | 15632 | 1249 |
Cpeb4,Herc6,Parp11,Pcdh7,Pkp4,Cmpk2,Cd86,Osm,Ampd3,St3gal5,Alas1,Slc25a12,Syne2,Oas2,Ccnd2,Dtx3l,Ifih1,Traf5,1600014C10Rik,Pde3b,Hvcn1,Slfn5,Tap1,Nlrc5,Tank,Parp14,Irgm2,Ccr3,Ifi44,Gbp4,Gbp9,Peli1,Tnfsf8,Dhx58,Samd9l |
| 2.510e-06 | -12.90 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_UP | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_UP | 190 | 35 | 15632 | 1249 |
Zeb1,Bcorl1,Tmem26,Rnf19a,Sh3bp4,Tmem123,Irak2,Nfxl1,Hcar2,Dusp5,Hp,Il2rg,Stat3,Dusp4,Ap3b1,Vcan,Chst11,Aebp2,Slc16a3,Lrp4,Parp8,Crbn,Dusp1,Gadd45b,Bcl6,Cd14,Sla,Tnfaip3,Zc3hav1,Rhoc,Aff1,Arl4a,Irs2,Hif1a,Sgms2 |
| 2.510e-06 | -12.90 | GSE43955_1H_VS_60H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_1H_VS_60H_ACT_CD4_TCELL_UP | 190 | 35 | 15632 | 1249 |
Ifit3b,Kcna3,Adora2b,Rcan1,Rac3,Itga5,Ptger4,Plaur,Clic4,Ikbke,Bcl2a1a,Il1rn,Il10,Ifit3,Tmem176a,Alas1,H2-Aa,Phlda1,Pdgfb,Cnn3,Traf1,Nxf1,Usp18,Mdfic,Angpt1,Fcgr1,Cyfip1,Txnrd1,Bcl2a1b,Dusp1,Prdx5,Tapbp,Bcl2a1d,Cox17,Tor1aip2 |
| 2.512e-06 | -12.89 | GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_DN | 182 | 34 | 15632 | 1249 |
Fas,Prdm1,Nfkbiz,Slc30a1,Rnd3,Plau,Slamf7,Spsb1,Phldb1,Ttc39c,Birc2,Il6,Mdm2,Lztfl1,Cebpd,Etnk1,Kpna3,Ptgs2,Trib3,Map3k8,Il12b,Mthfd2,Kif3c,Clcf1,Serpinb2,Tnfaip2,Ppp2r2a,Dnajb2,Gch1,Tnfsf14,Samsn1,Ddit4,Plscr1,Il18rap |
| 2.512e-06 | -12.89 | GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP | MSigDB lists | GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP | 182 | 34 | 15632 | 1249 |
Gfi1,Fmnl2,Cxcl10,Lyn,Ptprj,Prdm9,Pou2f2,Tmem26,Atxn7l1,Irf8,Cd86,Tnfrsf1b,Ccl5,Slc7a8,Irak3,Slc28a2,Ripk3,Hk3,Ccdc88b,Sla,Ubash3b,Upp1,Mcm10,Gpr35,Aftph,Stap1,Fcgr2b,Ctsc,Ikzf1,Csf3r,Gpr18,Ppp1r14b,Nlrc5,Spn |
| 2.512e-06 | -12.89 | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP | MSigDB lists | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP | 182 | 34 | 15632 | 1249 |
Phf6,Mthfd2,Ebi3,St3gal1,Endod1,Oas1g,Hmox1,Cd200,Fam162a,Pkp4,Pgk1,Casp4,Il12rb1,Oas1a,Stx11,Ksr1,Pdlim7,Rab19,Marcksl1,Egr1,Cd38,Ppfibp1,Batf,Cd83,Sla,Bcl6,Gadd45b,Hivep2,Casp1,Cox17,Tnc,Abcb1a,Carhsp1,Tnfsf8 |
| 2.521e-06 | -12.89 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | 42 | 14 | 15632 | 1249 |
Phlda1,Errfi1,Dusp4,Maff,Slc7a11,Dusp6,Gem,Egr3,Mxd1,Plk3,Dusp5,Egr1,Lif,Trib1 |
| 2.550e-06 | -12.88 | MODULE_24 | MSigDB lists | MODULE_24 | 416 | 61 | 15632 | 1249 |
Nfil3,Ldlr,Acsl1,Ier3,Trib1,Pim2,Ell2,Itga5,Smpdl3b,Ppp4r2,Slpi,Alas1,Cnn3,P4ha1,Ikbkg,Tnfrsf1b,S100a8,Dnase1l3,Gclc,Htr2a,F10,Cdk5r1,Il4ra,Pttg1,Sdc1,Gadd45g,Stard5,Gclm,Cited2,Ets2,Zyx,Spn,Ifit1bl1,Glrx,Pf4,Il1rn,Pim1,Ak4,Tgfbi,Phyh,Hmox1,Smox,Hp,Hap1,Ddit4,Ube2l6,Serpine1,Ppp1r15a,Gch1,Gdf15,Junb,Ifit1bl2,Cd14,Rnd1,Mthfr,Nupr1,Plk3,Ccnd1,Pnp2,Csf3r,Cst7 |
| 2.582e-06 | -12.87 | positive regulation of toll-like receptor signaling pathway | biological process | GO:0034123 | 25 | 10 | 20694 | 1406 |
Tlr2,Tlr1,Wdfy1,Nr1h3,Rsad2,Cav1,Peli1,Tlr9,Tlr3,Treml4 |
| 2.631e-06 | -12.85 | GSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN | MSigDB lists | GSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN | 151 | 30 | 15632 | 1249 |
Nmi,Ext1,Snx10,Birc3,Atp6v1d,Chd9,Nfkb2,Arf4,Nlgn2,Dusp16,Epsti1,Ppa1,Crkl,Sema4a,Asb13,Trib1,Ggct,Triobp,Tmem184b,Ptpn2,Trip10,Ube2f,Rnd3,Slc25a25,Zbtb5,Relb,Nupr1,Malt1,Aldh1b1,Sgms2 |
| 2.717e-06 | -12.82 | TNFR2 non-canonical NF-kB pathway | REACTOME pathways | R-MMU-5668541 | 98 | 24 | 8608 | 757 |
Birc2,Psme2b,Tnfsf9,Tnfrsf1b,Tnfrsf8,Tnfsf14,Psme2,Psma6,Tnfsf15,Tnfsf4,Psmd10,Relb,Traf2,Birc3,Psmb8,Psmb10,Tnfsf8,Psmb6,Cd40,Psme1,Tnfrsf14,Psmb9,Nfkb2,Tnf |
| 2.732e-06 | -12.81 | GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_UP | MSigDB lists | GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_UP | 159 | 31 | 15632 | 1249 |
Ifit1bl1,D16Ertd472e,Dnaja1,Znfx1,Itgb8,Sat1,Atp13a1,Rin2,Fgl2,Tlk2,Pml,Usp25,Dtx3l,Pttg1,Extl2,Cd38,Rnf31,Slc31a2,Ifit1bl2,Rgl1,Med21,Cenpj,Noc4l,Trim26,Oas1a,Oasl1,Oas1g,Ppa1,Fscn1,Sp110,Fmnl2 |
| 2.743e-06 | -12.81 | cellular response to transforming growth factor beta stimulus | biological process | GO:0071560 | 124 | 24 | 20694 | 1406 |
Sirt1,Dcp1a,Ptk2,Fut8,Igf1r,Crkl,Cav1,Serpine1,Apaf1,Nr3c1,Src,Gcnt2,Col4a2,Ccl2,Acvrl1,Pml,Zyx,Bmp2,Acvr1,Cited2,Acvr1b,Bambi,Fos,Jun |
| 2.761e-06 | -12.80 | KIM_WT1_TARGETS_DN | MSigDB lists | KIM_WT1_TARGETS_DN | 417 | 61 | 15632 | 1249 |
Rin2,Pla2g4a,Cited2,Trmt1l,Sod2,Gadd45b,Cenpe,Spn,Ifit1bl1,Ifi207,Pilrb2,Pikfyve,Cdk5r1,Ifi214,Arl4a,Plagl1,Ifi203,Sirt1,Ifi211,Cep350,Plod2,Mndal,Lmo4,Sema3c,Marco,Asf1a,Zcchc2,Fam111a,Dnajb4,Ifi204,Nox1,Ccng2,Ccnd1,Gpsm2,Ifi205,Serp1,Ifi209,Armcx6,Ifi213,Apaf1,Trim12c,Irf2,Itga4,Rapgef2,Ifi208,Ddit4,Fubp1,Ascc3,Med21,Flrt2,Plk2,Daam1,Asns,Gja1,Ifit1bl2,Pkp4,Stip1,Rsbn1,Pilrb1,Snapc1,Crkl |
| 2.793e-06 | -12.79 | Toll-Like Receptors Cascades | REACTOME pathways | R-MMU-168898 | 132 | 29 | 8608 | 757 |
Ppp2r1b,Nfkbib,Nfkbia,Tlr6,Tlr1,Map3k8,Peli1,Fos,Tlr3,S100a8,Tab2,Nod2,Tlr9,Map2k4,Nfkb1,Dusp4,Dusp6,Jun,Mapkapk2,Irak2,Nod1,Nfkb2,Cd180,Cd14,Myd88,Irf7,Tlr2,Ikbkg,Ripk2 |
| 2.798e-06 | -12.79 | Map3k1 (mitogen-activated protein kinase kinase kinase 1) | protein interactions | 26401 | 19 | 10 | 7778 | 753 |
Map2k4,Ikbkg,Cd40,Map2k1,Stat3,Traf2,Map4k4,Birc3,Jun,Birc2 |
| 2.798e-06 | -12.79 | Nfkb1 (nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105) | protein interactions | 18033 | 19 | 10 | 7778 | 753 |
Relb,Nos2,Hdac1,Il6,Map3k8,Nfkbiz,Nfkb2,Nfkbia,Sele,Nfkb1 |
| 2.801e-06 | -12.79 | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP | MSigDB lists | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP | 167 | 32 | 15632 | 1249 |
Hdac1,Kdm5b,Egr2,Gpr18,Serp1,Tmem184b,Klf3,Parp8,Ifit2,Plekhf2,Tnfrsf14,Daxx,Mdfic,Rbm43,Ddx58,Gbp3,Irf2,Evl,Mxd1,Egr1,Pdlim7,Itgal,Irf8,Birc3,Rnf14,Sesn3,Dio2,Cmpk2,Lyn,Cpeb4,St3gal1,Ptger4 |
| 2.841e-06 | -12.77 | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN | 175 | 33 | 15632 | 1249 |
Irf8,Tor3a,S100a8,Rabgef1,4930523C07Rik,Wars,Oas1a,Isg20,Lyn,Oas1g,Psmb6,Il13ra1,Cd200,H2-Ab1,Sp110,Tcf4,Jun,Tspan3,Swap70,Itpr1,Syk,Cept1,Cox17,Slc15a3,Stap1,Irf4,Il4ra,Cd74,Cd180,Hhex,Cd38,Sav1,Zbtb5 |
| 2.841e-06 | -12.77 | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP | 175 | 33 | 15632 | 1249 |
Plek,Dach1,Irf7,Irf8,Higd1a,Daam1,Slc7a5,Flnb,Egln3,Dusp5,Dck,Tgfbi,Odc1,Adam19,Cmklr1,Gfi1,Zhx2,Slc7a11,Ppp1r14b,Ifit2,Plac8,Tcf4,Tspan3,Fchsd2,Cers6,Rhoh,Mapkapk2,Cdk5r1,P2ry14,Kmo,Mdfic,Crim1,Cd164 |
| 2.841e-06 | -12.77 | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_DN | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_DN | 191 | 35 | 15632 | 1249 |
Cd302,Ifit1bl1,Slc25a37,Ddhd1,Casp1,Ogfrl1,Aebp2,Rsad2,Cebpd,Dock10,Cers6,Parp14,Slc44a1,Igsf6,Tnfsf8,Usp18,Rgs3,Pilrb2,Rbm43,Cdc42ep2,Zbp1,Lcp2,Ptch1,Ifit1bl2,Oas1a,Pou2f2,Ddit4,Spire1,Mmp9,Oas1g,Filip1l,Rtn1,Ripk2,Pilrb1,Chd9 |
| 2.853e-06 | -12.77 | GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_UP | MSigDB lists | GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_UP | 183 | 34 | 15632 | 1249 |
Phlda1,Zeb1,Pdgfb,Dcp1a,Vasp,Hivep3,Ppp1r15b,Junb,Tnfaip2,Rgs1,Bcl2a1a,Itga5,Itpkc,Max,Map2k4,Usp42,Trib1,Irf4,1110038F14Rik,Bcl2a1d,Optn,Mllt6,Errfi1,Pik3r5,Bcl2a1b,Ifnar1,Ctu1,Cd40,Pim3,Rhoc,Fas,Magohb,Il4ra,Icam1 |
| 2.853e-06 | -12.77 | GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP | 183 | 34 | 15632 | 1249 |
Fos,Rgs14,Csf3r,Tcf4,Jun,Axl,Dusp1,Ifit2,Psip1,Fgl2,Cebpd,D1Ertd622e,Pnp2,Kat2b,Usp18,Zfp281,Abr,Atf3,Daxx,Prdx1,Mov10,Ifit3,Irf8,Fosb,Rgl1,Dusp6,Uba7,Isg20,Nmi,Zfp36,Irf1,Ifit3b,Pkp4,Sh3bgrl2 |
| 2.853e-06 | -12.77 | GSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_DN | MSigDB lists | GSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_DN | 183 | 34 | 15632 | 1249 |
Gclm,Irgm2,Slc44a1,Ly75,Cish,Errfi1,Sod2,Plekha5,Tpst1,Birc2,Pbx1,Ifit1,Nfkbiz,F11r,Sdc1,Irs2,Cx3cl1,St3gal6,Pdk3,Gja1,Myo1b,Casp4,Lmo4,Gem,Cxcl1,Etnk1,Mmp9,Traf3ip2,Cd200,Lpar1,Rcn1,Dnajb4,Cdc42ep4,Serpinb9 |
| 2.853e-06 | -12.77 | GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 183 | 34 | 15632 | 1249 |
Relb,Rab3ip,Ifit1,Nod1,Sdc4,P2ry14,Ifih1,Usp18,Dhx58,Hdac1,Ubtd2,Ifi44,Fchsd2,Slc44a1,Tnfsf8,Birc2,Tcf4,Ets2,Arid5a,Homer1,Insl6,Stat5a,Abcc1,Pmepa1,Pkp4,Nfkb2,Nr4a3,Cacnb3,Parp11,Cd200,Pcgf5,Procr,Pdgfb,Rel |
| 2.861e-06 | -12.76 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:0043154 | 92 | 20 | 20694 | 1406 |
Il6,Prdx5,Rnf34,Birc2,Rffl,Cdkn2d,Cflar,Bcl2a1d,Tnfsf14,Serpinb9,Ptgs2,Adora2a,Mdm2,Thbs1,Hspa1b,Mmp9,Src,Birc3,Plaur,Nr4a1 |
| 2.872e-06 | -12.76 | CROMER_TUMORIGENESIS_UP | MSigDB lists | CROMER_TUMORIGENESIS_UP | 54 | 16 | 15632 | 1249 |
Tnc,Pdpn,Il6,Myo1b,Serpine1,Plod3,Plaur,Tnfaip3,Il1b,Plau,Col4a2,Odc1,Smox,Uchl1,Oasl1,Mmp9 |
| 2.880e-06 | -12.76 | 25A_SYNTH_1 | prosite domains | PS00832 | 5 | 5 | 13278 | 1037 |
Oas2,Oasl2,Oas3,Oas1a,Oas1g |
| 2.883e-06 | -12.76 | GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | 107 | 24 | 15632 | 1249 |
Ifi204,Gfi1,Nfil3,Nfxl1,Mndal,Dach1,Jdp2,Ifi203,Ifi211,Btg2,Ifi208,Zfp281,Ifi214,Mxd1,Atf3,Prdm1,Hhex,Ifi207,Hinfp,Ifi205,Ets2,Ifi209,Ifi213,Aebp2 |
| 2.889e-06 | -12.75 | Toll Like Receptor 5 (TLR5) Cascade | REACTOME pathways | R-MMU-168176 | 73 | 20 | 8608 | 757 |
Myd88,Tab2,Fos,Nfkb1,Map2k4,Ripk2,Nod2,Ikbkg,Dusp4,Nfkbib,Jun,Dusp6,Ppp2r1b,Map3k8,Nod1,Irak2,Peli1,Nfkb2,Mapkapk2,Nfkbia |
| 2.889e-06 | -12.75 | MyD88:Mal cascade initiated on plasma membrane | REACTOME pathways | R-MMU-166058 | 73 | 20 | 8608 | 757 |
Ppp2r1b,Dusp4,Nfkbib,Jun,Dusp6,Mapkapk2,Nfkbia,Nod1,Map3k8,Irak2,Peli1,Nfkb2,Fos,Tab2,Myd88,Nod2,Ikbkg,Nfkb1,Ripk2,Map2k4 |
| 2.889e-06 | -12.75 | Toll Like Receptor 10 (TLR10) Cascade | REACTOME pathways | R-MMU-168142 | 73 | 20 | 8608 | 757 |
Myd88,Tab2,Fos,Nfkb1,Ripk2,Map2k4,Ikbkg,Nod2,Jun,Dusp6,Dusp4,Nfkbib,Ppp2r1b,Nfkb2,Peli1,Map3k8,Nod1,Irak2,Mapkapk2,Nfkbia |
| 2.889e-06 | -12.75 | MyD88 cascade initiated on plasma membrane | REACTOME pathways | R-MMU-975871 | 73 | 20 | 8608 | 757 |
Map2k4,Ripk2,Nfkb1,Nod2,Ikbkg,Myd88,Tab2,Fos,Irak2,Nod1,Map3k8,Nfkb2,Peli1,Nfkbia,Mapkapk2,Nfkbib,Dusp4,Dusp6,Jun,Ppp2r1b |
| 2.889e-06 | -12.75 | Toll Like Receptor TLR6:TLR2 Cascade | REACTOME pathways | R-MMU-168188 | 73 | 20 | 8608 | 757 |
Nfkbia,Mapkapk2,Nfkb2,Peli1,Irak2,Map3k8,Nod1,Ppp2r1b,Dusp6,Jun,Nfkbib,Dusp4,Ikbkg,Nod2,Map2k4,Ripk2,Nfkb1,Fos,Tab2,Myd88 |
| 2.889e-06 | -12.75 | Toll Like Receptor 2 (TLR2) Cascade | REACTOME pathways | R-MMU-181438 | 73 | 20 | 8608 | 757 |
Dusp6,Jun,Nfkbib,Dusp4,Ppp2r1b,Nfkb2,Peli1,Irak2,Nod1,Map3k8,Nfkbia,Mapkapk2,Myd88,Tab2,Fos,Map2k4,Ripk2,Nfkb1,Ikbkg,Nod2 |
| 2.889e-06 | -12.75 | Toll Like Receptor TLR1:TLR2 Cascade | REACTOME pathways | R-MMU-168179 | 73 | 20 | 8608 | 757 |
Tab2,Myd88,Fos,Ripk2,Map2k4,Nfkb1,Nod2,Ikbkg,Nfkbib,Dusp4,Dusp6,Jun,Ppp2r1b,Irak2,Map3k8,Nod1,Peli1,Nfkb2,Mapkapk2,Nfkbia |
| 2.893e-06 | -12.75 | PARP | pfam domains | PF00644 | 15 | 8 | 18711 | 1348 |
Parp11,Parp12,Tiparp,Parp3,Parp8,Parp14,Zc3hav1,Parp10 |
| 2.919e-06 | -12.74 | wound healing | biological process | GO:0042060 | 271 | 40 | 20694 | 1406 |
Bcl9,P2ry12,Cflar,Cx3cl1,Pdpn,Ap3b1,Cnn2,Lox,Il1a,Dst,Ubash3b,Stxbp1,Lnpk,Hif1a,F10,Cdkn1a,Ptprj,Sdc4,Adrb2,Pf4,Evl,Dcbld2,Acvrl1,Plek,Plau,Cav1,Notch2,Slc7a11,Papss2,Sdc1,Hmox1,Ifrd1,Timp1,Gja1,Stxbp3,Serpinb2,Axl,C3,Enpp4,Procr |
| 2.919e-06 | -12.74 | CHICAS_RB1_TARGETS_GROWING | MSigDB lists | CHICAS_RB1_TARGETS_GROWING | 224 | 39 | 15632 | 1249 |
Cacybp,Asns,Cav1,Mndal,Psat1,Ltbp2,Ifi203,Ddit4,Ifi211,Nmi,Timeless,Tifa,Ifi208,Ifi204,Mcm6,Arid5b,Tnfsf4,Dek,Nfxl1,Pcdh7,Rbbp8,Ifi205,Ifi209,Ifi213,Axl,Ezr,Psip1,Apobec3,Dock10,Cers6,C1ra,Phgdh,Tpx2,Arl4a,Ifi214,Nupr1,Egr1,Ifi207,Olfml3 |
| 2.936e-06 | -12.74 | positive regulation of production of molecular mediator of immune response | biological process | GO:0002702 | 100 | 21 | 20694 | 1406 |
Rsad2,Il4ra,Nod2,Tnfrsf14,Tlr2,Hk1,Clcf1,Nr4a3,Ddx58,Cd40,Il6,Traf2,Cd74,Nlrp3,Tnfsf4,Il1b,Arid5a,Tlr9,Il18,Fzd5,Malt1 |
| 2.937e-06 | -12.74 | PATTERSON_DOCETAXEL_RESISTANCE | MSigDB lists | PATTERSON_DOCETAXEL_RESISTANCE | 37 | 13 | 15632 | 1249 |
Ifi203,Ccng2,Ifi208,Rnf24,Ifi211,Ifi205,Ifi209,Mndal,Ifi213,Ifi207,Ifi214,Ifi204,Stat1 |
| 2.937e-06 | -12.74 | PID_GMCSF_PATHWAY | MSigDB lists | PID_GMCSF_PATHWAY | 37 | 13 | 15632 | 1249 |
Jak2,Stat1,Lyn,Pim1,Cish,Stat3,Syk,Ccl12,Stat5a,Map2k1,Osm,Fos,Irf8 |
| 2.957e-06 | -12.73 | morphogenesis of a branching epithelium | biological process | GO:0061138 | 195 | 32 | 20694 | 1406 |
Il6,Pdgfb,Cited2,Flt1,Kdr,Tnc,Socs3,Pml,Il10,Acvr1,Bmp2,Sema3c,Timeless,Met,Src,Angpt1,Spry2,Pbx1,Ahr,Csf1,Clic4,Edn1,Ptch1,Tmem67,Spint2,Mmp14,Kdm5b,Notch1,Hhex,Hmga2,Myc,Fzd5 |
| 3.032e-06 | -12.71 | GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN | MSigDB lists | GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN | 152 | 30 | 15632 | 1249 |
Irs2,Sell,Bcor,Rab3ip,Rras2,Crlf3,Dse,Usp53,Sele,Lztfl1,Treml2,Peli1,Myc,Fchsd2,Tnfsf8,Mdn1,Filip1l,Hmgcs1,Larp1,Ptk2,Wdr43,Igf1r,Ikbke,Znrf1,Sesn3,Arid4a,Atm,Dgka,Tlr1,Cnn3 |
| 3.032e-06 | -12.71 | GSE3920_UNTREATED_VS_IFNA_TREATED_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE3920_UNTREATED_VS_IFNA_TREATED_ENDOTHELIAL_CELL_DN | 152 | 30 | 15632 | 1249 |
Cd82,Znrf1,Gfi1,Zhx2,Ppa1,Atp10a,Mcm6,Asb13,Mppe1,Flnb,Zeb1,Rasgrp1,Cd69,Xaf1,Stat4,Atm,Ifit1bl2,Hopx,Pnpt1,Daxx,Evl,Ifih1,Kmo,Setdb2,Ccr3,Nr3c1,Ifit1bl1,Gpsm2,Itpr1,Ttc39c |
| 3.034e-06 | -12.71 | regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001242 | 168 | 29 | 20694 | 1406 |
Ptgs2,Bcl2a1d,Sod2,Hif1a,Bcl2a1b,Map2k1,Plaur,S100a8,Bcl2l11,Src,Bcl2a1a,Plscr1,Hdac1,Hsph1,Nck1,Ripk3,Nupr1,Cdkn2d,Cav1,Ikbkg,Nox1,Dnaja1,Cd74,Grina,Mmp9,Sirt1,Plagl2,Ptpn2,Mdm2 |
| 3.063e-06 | -12.70 | Map3k7 (mitogen-activated protein kinase kinase kinase 7) | protein interactions | 26409 | 41 | 15 | 7778 | 753 |
Vrk2,Traf2,Ikbkg,Cd40,Tnip3,Ppm1l,Tab2,Traf3ip2,Birc2,Birc3,Malt1,Myd88,Syk,Map2k4,Tlr3 |
| 3.076e-06 | -12.69 | metal ion homeostasis | biological process | GO:0055065 | 643 | 75 | 20694 | 1406 |
Atp13a1,Cd40,Cutc,Ccrl2,Edn1,Ccl5,Cxcl2,Htr2a,Slc12a9,Bnip3,Myc,Fpr1,Ednrb,Ptgir,Ccr3,Atp2b4,Ptger4,Cmklr1,Kdr,Cxcl1,Cacna1d,Sod2,P2ry2,Ccl3,Cx3cl1,Mt2,Adrb2,Slc30a1,Slc9a1,Ccl2,Gpr35,Pml,Mllt6,Ccr1,Cx3cr1,Sco1,Cp,Slc30a4,Slc31a1,Marcksl1,Slc39a4,Htr2b,Gja1,Itgav,Itpr1,Jak2,Cxcl3,Cav1,Slc31a2,Hmox1,Prkce,Gpr18,Swap70,Grina,Slc39a14,Tmtc2,Il1b,Tmem178,1600014C10Rik,Ero1l,Hif1a,Cxcl10,Lpar1,Rmdn3,Gna15,Cacnb3,Cd38,Mt1,Slc39a13,Prnp,Xcr1,Snx10,Lcn2,Fpr2,Hap1 |
| 3.082e-06 | -12.69 | Focal Adhesion-PI3K-Akt-mTOR-signaling pathway | WikiPathways | WP2841 | 320 | 63 | 4813 | 540 |
Ifnb1,Pik3cd,Phlpp1,Itgb8,Ikbkg,Kitl,Tnc,Flt1,Hif1a,Lipe,Tbc1d1,Pdgfrb,Gng12,Ifna2,Csf1,Itgav,Gys1,Angpt1,Mdm2,Pik3r5,Ppp2r3a,Slc2a1,Jak2,Kdr,Pfkfb3,Pdgfc,Akt3,Il2rg,Phlpp2,Gnb4,Ppp2r5a,Csf3r,Ifna4,Col4a2,Itgal,Ppp2r1b,Ifnar1,Itga9,Osm,Rab10,Itga4,Ifna5,Col11a2,Itga5,Pdgfb,Ptk2,Gng4,Igf1r,Ifna1,Map2k1,Nos2,Irs2,Vegfc,Cdkn1a,Thbs1,Il4ra,Ifna6,Lpar1,Ddit4,Csf3,Met,Mtcp1,Gng11 |
| 3.112e-06 | -12.68 | primary metabolic process | biological process | GO:0044238 | 6373 | 510 | 20694 | 1406 |
Trim12a,Ell2,Hopx,Dcun1d3,Usp31,Mecp2,Znrf3,Parp14,Scyl2,St3gal1,Tlr9,Parp8,Pgs1,Aff1,Ifih1,Birc2,Dusp16,Ppp4r2,Rnf19b,Kmo,Myc,Pde5a,Plagl2,Dcp1a,Phyh,Ikbke,Pdgfb,Ak4,Ero1l,P4ha2,Tpst1,4932438A13Rik,Ampd3,Tnks1bp1,Smpdl3b,Src,Parp12,Stat3,Hck,Il12rb1,Trib1,Ripk3,Mcm10,Adar,Crkl,Hat1,Bcor,Stat1,Usp35,Mcm6,Ranbp2,Dnase1l3,Hk3,Mthfd1l,Swap70,Magohb,Mdfic,Ubash3b,Gfpt1,Phlpp2,Setdb2,Kdr,Egr2,Plaat3,Met,Rcl1,Serp1,Myd88,Psat1,Zhx2,Egr1,Fut8,Kmt5a,Ube2e2,Hmgcs1,Ext1,Mark2,Plod2,Cnot4,Cgas,Il1rn,Kdm6b,Mmp25,Dusp4,Plod3,Ppp1r15a,Cflar,Sap30,Dusp8,Kdm4a,Hif1a,Pgm1,Ccnd2,Ubr4,Ddhd1,Samhd1,Ctsc,Prdm9,Slfn8,Grk3,Plk2,Thbs1,Fbxo4,Trem1,Prnp,Pcx,Ccnd1,Hk2,Il4i1,Casp3,Itgav,Mapkapk2,Mppe1,Pttg1,Hmga2,Ppp2r3a,Dtx2,Tmtc2,Extl2,Mdm2,Egln3,Ptger4,Mov10,Hdc,Tgs1,Mmp13,S100a8,Tnfsf4,Hinfp,Acvr1,Yju2,B4galt4,Hdac1,Plau,Gbgt1,Adam19,Pla2g7,Sgms2,Tent2,Xrn1,Trim21,Cop1,Morc3,Enpp4,Dhrs9,Itgb8,Gadd45g,Irak3,Zfp36,Irgm2,Parp9,Endod1,Nos2,Smc5,Htra1,Cmpk2,Ass1,Aoah,Nmi,Tlk2,Ptprj,Map4k4,Trmt1l,Dyrk2,Icosl,Gcnt2,Asns,Plpp1,Tlr2,Pim1,Vcpip1,Znrf1,Lipe,Tiparp,Irak2,Trim36,Syk,Stat4,Agpat4,Pml,Pim2,Zc3h12c,Ccnj,Eya4,Ago3,Bfar,Noct,Col4a2,Cdkn2d,Nod1,Ccl5,Psip1,Igf1r,Larp1,Map3k6,Vrk2,Fgr,Wars,Cd74,C3,Dusp28,Oas2,Psmb6,Rnf31,Junb,Malt1,Prpf4,Rnaset2b,Fos,Olr1,Ankib1,Upp1,Tent4a,Atm,Acsl1,Isg20,Dusp2,Degs2,Timeless,Cdyl,Tnip1,Lyn,Chst11,Ahr,C1rl,Parp11,Helz2,Usp18,Htr2b,Ptch1,Lmo4,Acsl5,Axl,Trim13,Txnrd1,Fam20c,Arf4,Stat5a,Ascc3,Map3k8,Ppm1k,Eif2ak2,Pnpt1,Socs1,Pdpn,Eef1e1,Herc6,Inpp1,Arid4a,Socs3,Slfn9,Rnf34,Apobec3,Birc3,Psmb8,Psmb9,Gtpbp2,Dcp2,Arrdc4,Med21,Cept1,Batf,Dnajb2,Zc3h7a,Snapc1,Ccng2,Il15,Nupr1,Dusp14,Dgkh,Rhoq,Gda,Ptk2,Nr1h3,Ch25h,Fosb,Kdm5b,Prkx,Prag1,Gbe1,Ptpn2,Pdgfrb,Tnfsf15,Ube2e1,Gpc1,Wdr43,Dpy19l1,Psma6,Lif,Arg2,Usp12,Flt1,Oas1a,Odc1,Map2k1,Pdk3,Trim12c,Eif4g2,Nr3c1,Phlda1,Peli1,Rictor,Ptges,Tnfaip3,Irf7,Pgk1,Inhba,Tyk2,Tcea1,Sphk1,Jak2,Akt3,Pdss1,Rnf139,Spsb1,Rffl,Inpp5b,Sik3,Dusp6,Denr,Pikfyve,Casp8,Nampt,Rbbp8,Trim56,Eno2,Uba7,Gys1,Pla2g4a,Rnf19a,Nck1,Acvrl1,Srgn,Tmem67,Bnip3,Psmb10,Tra2a,Tha1,Mcm9,Otud1,Lox,Phgdh,Saa3,Pgap2,Dusp1,Acvr1b,Casp2,Bmp2,Ube2l6,Cpeb4,Dck,Plek,Ppm1l,Ppp2r5a,Prkce,Cdk5r1,Keap1,Tlr3,Plat,Ifnar1,Polr2g,Tet2,Trib3,Pim3,Sla,Isg15,Il1b,Acp2,Mlkl,Ttc39b,St3gal5,Btg2,Hsd17b12,Tspo,Naa25,Plpp3,Usp42,Hspa1a,Cnp,Asf1a,Map2k4,Ppp1r15b,Rars,Phlpp1,Gk,Pigv,Klhl25,Hmga1,Papss2,Ube2f,Rubcnl,Nsd3,Trip13,Prkar2b,Socs7,Cish,Edn1,Mmp14,Sgk3,Cers6,Mtmr14,C1ra,Med13,Casp7,Ccr3,Gclm,Dtx3l,Svbp,Ep400,Irf4,Lnpep,Usb1,Stk40,Ripk2,Mul1,Mvp,Gpd2,Rnf14,Nek6,Usp25,Mthfr,Traf2,Jarid2,Casp1,Ccne1,Idi1,Dgka,Rrs1,Rnaset2a,Smg7,Ldlr,Tut7,Casp4,B3gnt5,Hivep2,Hsd17b7,Top3a,Sbds,Usp53,Crbn,Mocs1,Chmp4b,Mdn1,Il18,Fgl2,Zc3h12a,Tcf4,Pcgf5,Jun,Lap3,Mapkbp1,Tnf,Plk3,Rnf135,Atf3,Parp10,Cpd,Taf4b,Armc8,St3gal6,Asah2,Acpp,Ccl12,Dse,Etnk1,Prpf38a,Jmjd6,Kat2b,Slc16a1,Uchl1,Hk1,Pfkl,Nlgn2,Dr1,Parp3,Gclc,Adgb,Nt5c3,Lpcat2,Lipg,P4ha1,Oasl2,Ksr1,Mmd,Mgat1,Ptgs2,Nfil3,Ddx4,Tpi1,F10,Ppp2r2a,Mrpl52,Marf1,Pik3cd,Ldha,Plscr1,Sde2,Dusp5,Osm,St3gal3,Cav1,Adhfe1,Pbx1,Trim30a,Acod1,Ctu1,Plcl2,Arel1,Sirt1,Mmp9 |
| 3.115e-06 | -12.68 | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | MSigDB lists | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | 328 | 51 | 15632 | 1249 |
Gadd45g,Dusp4,Pde5a,Tor1aip2,Bnip3,Fos,Jun,Plac8,Klf3,Bcl2l11,Rbl1,Pim3,Rnd3,Rbm43,Tspo,Prnp,Nfkbiz,Egr1,Pla2g7,Rnf19a,Egln3,Trim21,Akt3,Isg20,Casp8,Pfkl,Idi1,Fam111a,Stat1,Errfi1,Tapbp,Ccng2,Oaf,Rab9,Cp,Klf6,Plekhf2,Gbp2,Olfml3,Ier2,AA467197,Higd1a,Ppp1r15a,4930523C07Rik,Dusp6,Gcnt2,Irak2,Pim1,Arid5b,Kdm6b,Pcgf5 |
| 3.125e-06 | -12.68 | GO_INTERACTION_WITH_HOST | MSigDB lists | GO_INTERACTION_WITH_HOST | 122 | 26 | 15632 | 1249 |
Ifit1bl2,Cav1,Tap2,Cd86,Casp8,Kpna3,Cd55,Zc3h12a,Itga5,Clec5a,Serpinb9,Ldlr,Tnip1,Eif2ak2,Ifit1bl1,Axl,Bcl2l11,Itgav,Hspa1a,Icam1,F11r,Htr2a,Cd80,Tnfrsf14,Zc3hav1,Tap1 |
| 3.134e-06 | -12.67 | GSE5099_CLASSICAL_M1_VS_ALTERNATIVE_M2_MACROPHAGE_UP | MSigDB lists | GSE5099_CLASSICAL_M1_VS_ALTERNATIVE_M2_MACROPHAGE_UP | 160 | 31 | 15632 | 1249 |
Nkiras1,Spata13,Upp1,Gbp3,Ifih1,Il4ra,Mpp7,Samhd1,Znfx1,Arid5a,Mgat1,Nfkbia,Plac8,Gypc,Cept1,Rsad2,Pnp2,Parp11,Atp10a,Cd55,Sema4c,Epsti1,Lrrc8c,Ap3m2,Rgs1,Plekha2,Pde4b,P4ha1,Tuba4a,Il12rb1,Psme2 |
| 3.140e-06 | -12.67 | Salmonella infection | KEGG pathways | ko05132 | 78 | 21 | 7931 | 713 |
Ccl3,Cd14,Jun,Dync1h1,Il18,Nfkb1,Cxcl1,Fos,Cxcl3,Nos2,Flnb,Ccl4,Cxcl2,Il6,Actb,Il1a,Nlrc4,Myd88,Dync1i2,Casp1,Il1b |
| 3.140e-06 | -12.67 | Salmonella infection | KEGG pathways | mmu05132 | 78 | 21 | 7931 | 713 |
Flnb,Cxcl2,Ccl4,Actb,Il6,Myd88,Dync1i2,Nlrc4,Il1a,Il1b,Casp1,Ccl3,Dync1h1,Jun,Cd14,Nfkb1,Il18,Fos,Cxcl1,Nos2,Cxcl3 |
| 3.148e-06 | -12.67 | morphogenesis of an epithelium | biological process | GO:0002009 | 500 | 62 | 20694 | 1406 |
Hmga2,Hhex,Notch1,Mthfd1l,Ahr,Pbx1,Spint2,Lmo4,Ptch1,Gja1,Casp3,Flrt3,Bmp2,Src,Nr3c1,Sema3c,Timeless,Lhx2,Jag1,Vasp,Hif1a,Mthfr,Flt1,Pdgfb,Il6,Kdm5b,Prkx,Mmp14,Fzd5,Rpgrip1l,Myc,Sec24b,Plod3,Csf1,Spry2,Notch2,Tmem67,Sema4c,Edn1,Igf1r,Clic4,Sdc4,Intu,Acvr1,Pml,Il10,Casp8,Angpt1,Met,Acvrl1,Ift57,Apaf1,Pdpn,Fzd1,Stat5a,Socs3,Tnc,Kdr,Cited2,Tulp3,Vegfc,Phactr4 |
| 3.152e-06 | -12.67 | GO_POSITIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | 14 | 8 | 15632 | 1249 |
Il6,Rsad2,Nod2,Tnfsf4,Nlrp3,Il4ra,Cd74,Cd86 |
| 3.152e-06 | -12.67 | GO_REGULATION_OF_GRANULOCYTE_MACROPHAGE_COLONY_STIMULATING_FACTOR_PRODUCTION | MSigDB lists | GO_REGULATION_OF_GRANULOCYTE_MACROPHAGE_COLONY_STIMULATING_FACTOR_PRODUCTION | 14 | 8 | 15632 | 1249 |
Cd80,Rasgrp1,Il1b,Syk,Tlr9,Il12b,Il18,Ddx58 |
| 3.152e-06 | -12.67 | SA_MMP_CYTOKINE_CONNECTION | MSigDB lists | SA_MMP_CYTOKINE_CONNECTION | 14 | 8 | 15632 | 1249 |
Il1b,Tnfsf8,Tnfrsf8,Csf1,Sell,Tnfrsf1b,Spn,Tnf |
| 3.158e-06 | -12.67 | GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_MCMV_INFECTION_DN | MSigDB lists | GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_MCMV_INFECTION_DN | 137 | 28 | 15632 | 1249 |
Sdc4,Tnfaip3,Dnase1l3,Egr1,Csrnp1,Nfkbiz,Atf3,Ifi44,Stap1,Ikzf1,Ccl12,Dusp1,Nfkbia,Jun,Otud1,Nfkb2,Cd82,Cxcl1,Prdm9,Ier3,Map3k8,Ptgs2,Tifa,Tnfsf15,Btg2,Cxcl2,Ppp1r15b,Irf8 |
| 3.210e-06 | -12.65 | morphogenesis of a branching structure | biological process | GO:0001763 | 205 | 33 | 20694 | 1406 |
Kdm5b,Hmga2,Hhex,Notch1,Mmp14,Fzd5,Myc,Csf1,Pbx1,Ahr,Spry2,Ptch1,Edn1,Tmem67,Spint2,Clic4,Bmp2,Acvr1,Pml,Il10,Angpt1,Src,Met,Sema3c,Timeless,Prdm1,Flt1,Kdr,Tnc,Socs3,Il6,Cited2,Pdgfb |
| 3.211e-06 | -12.65 | perinuclear region of cytoplasm | cellular component | GO:0048471 | 644 | 75 | 20747 | 1409 |
Odc1,Cpd,Plscr1,Cyfip1,Lyn,Cdkn1a,Procr,Nfkbie,Ptch1,Lnpep,Rapgef2,Hdac1,Pla2g4a,Clic4,Prdx5,Stat1,Hmox1,Stxbp1,Stx6,Optn,Cx3cr1,Abcc5,Ptges,Cnp,Ccl2,Sele,Tlk2,Uaca,Cdk5r1,Mvp,Pikfyve,Oas2,Map2k1,Gbp2,Inhba,Grk3,Osbpl3,Vps54,Nos2,Cx3cl1,Dcun1d3,Csf1,Cav1,Myc,Fzd5,Slc9a1,Ddx4,Ehd1,Gbp3,Prkce,Cd34,Tnfrsf1b,Itpr1,Trim13,Fas,Myo1b,Rac3,Prkar2b,Mtmr14,Rab10,Anp32a,Pkp4,Hspa1a,Hap1,Slc39a13,Noct,Rab3ip,Mtdh,Src,Plaat3,Dst,Nupr1,Eif2ak2,Pde4b,Ezr |
| 3.211e-06 | -12.65 | BAUS_TFF2_TARGETS_UP | MSigDB lists | BAUS_TFF2_TARGETS_UP | 32 | 12 | 15632 | 1249 |
Ifit1bl1,Ifit1bl2,Psmb8,Irf7,Ogfr,Psmb9,Slfn4,Zeb1,Dgka,Slfn3,Samhd1,Tap1 |
| 3.211e-06 | -12.65 | GILDEA_METASTASIS | MSigDB lists | GILDEA_METASTASIS | 32 | 12 | 15632 | 1249 |
Dusp4,Ifi203,Ifi208,Ifi211,Ifi205,Mndal,Ifi209,Tagln,Ifi213,Ifi207,Ifi214,Ifi204 |
| 3.213e-06 | -12.65 | KEGG_FOCAL_ADHESION | MSigDB lists | KEGG_FOCAL_ADHESION | 192 | 35 | 15632 | 1249 |
Vasp,Met,Pdgfb,Akt3,Flnb,Col11a2,Cav1,Map2k1,Pdgfrb,Birc3,Igf1r,Vegfc,Actb,Thbs1,Kdr,Itga9,Pik3cd,Ptk2,Crkl,Rac3,Itga5,Ccnd1,Tnc,Itgb8,Jun,Zyx,Birc2,Flt1,Src,Itgav,Pik3r5,Pdgfc,Col4a2,Ccnd2,Itga4 |
| 3.213e-06 | -12.65 | GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_UP | 192 | 35 | 15632 | 1249 |
Cd83,Ahr,Palld,Nek6,Jmjd6,Traf1,Rnf135,Abcb1a,Casp3,Kcnj2,Ccng2,Casp1,Cst7,Slc16a3,Spsb1,Eif2ak2,Src,Axl,Ttc39c,Cyfip1,Slfn3,Nfil3,Ripk2,Endod1,Rnf19b,Rab20,Slpi,Flnb,Mmd,Tnfrsf1b,Sesn3,Psmb8,Casp4,Il10,Slfn4 |
| 3.232e-06 | -12.64 | GO_REGULATION_OF_INTERFERON_ALPHA_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERFERON_ALPHA_PRODUCTION | 18 | 9 | 15632 | 1249 |
Ripk2,Tlr3,Tlr9,Irf7,Ifih1,Il10,Ddx58,Nmi,Zc3hav1 |
| 3.233e-06 | -12.64 | GSE3982_MAST_CELL_VS_DC_DN | MSigDB lists | GSE3982_MAST_CELL_VS_DC_DN | 176 | 33 | 15632 | 1249 |
Trim14,Ppp2r3a,Oas1a,Hivep3,Slc31a2,Irf8,Il1rn,Prkar2b,Igf1r,Il13ra1,Oas1g,Rab20,Slamf8,Lpar1,Dusp2,Fchsd2,Nfkbie,Sdc2,Syk,Rgs14,Gpc1,Il15,Rbms2,Sdc4,Pilra,Samhd1,Hk3,Atf3,Hlx,Ccl22,Stat2,Kmo,Klf8 |
| 3.237e-06 | -12.64 | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_DN | 184 | 34 | 15632 | 1249 |
Fchsd2,Fcgr2b,Psma6,Scarf1,Tra2a,N4bp1,Syk,Tnf,Hsph1,Eno1,Ets2,Cited2,Olr1,Lrp8,Rhoh,Abr,Socs1,Prnp,Hif1a,Ccnd2,Bcl9,Cd69,Spint2,Stat4,Pde4b,Lcp2,Kdr,Prkx,Idi1,Il1rn,Cdkn1a,Ell2,Dusp5,Pim1 |
| 3.237e-06 | -12.64 | GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 184 | 34 | 15632 | 1249 |
Snn,Cd300lf,Rcan1,Arid5b,St3gal1,Cd200,Tmod3,Filip1l,Tmem176a,Kctd12,Ddit4,Cnn3,Klf2,Gbp7,Jarid2,Cd38,Klf7,Irak3,Sdc4,Lpcat2,Ddx58,Itga4,Kdm5b,B3gnt5,Samd9l,Parp14,Ctsc,Irgm2,Itpr1,Tet2,Arhgef3,Gpr18,Fam43a,Slc25a37 |
| 3.237e-06 | -12.64 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_DN | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_DN | 184 | 34 | 15632 | 1249 |
Il4i1,Sat1,Tnc,Tagln,Cx3cr1,Dusp1,Rbbp8,Spic,Col4a2,Tlr6,Aim2,Traf1,Flnb,Ppp4r2,Csf1,Mmd,Vasn,Dusp6,Slc13a3,Clec4n,Eno2,Slc4a7,Cd86,Marco,Sh3bgrl2,Pf4,Plaur,Ppfibp2,Slc31a1,Sema4a,Nr4a3,Il12b,Clec4d,Dnajb4 |
| 3.237e-06 | -12.64 | GSE36078_UNTREATED_VS_AD5_INF_MOUSE_LUNG_DC_DN | MSigDB lists | GSE36078_UNTREATED_VS_AD5_INF_MOUSE_LUNG_DC_DN | 184 | 34 | 15632 | 1249 |
Azi2,Rcn1,Slc43a3,Aida,Cdkn1a,Glrx,Dcbld2,Ust,Irak2,Ccl4,Osbpl3,Gem,Gbp7,Samsn1,Hopx,Irf8,Cd86,Slc7a8,Il12rb1,Flnb,St3gal6,Rhoc,Tsku,Clcn5,Gpc1,Rras2,Gpsm2,Swap70,Spic,Ehd1,Cenpe,Errfi1,Chst11,D1Ertd622e |
| 3.251e-06 | -12.64 | regulation of oxidoreductase activity | biological process | GO:0051341 | 85 | 19 | 20694 | 1406 |
Cox17,Slamf8,Gfi1,Lgals9,Hp,Gch1,Il1b,Atp2b4,Arg2,Htr2b,Edn1,Prdx5,Nod2,Nod1,Nfkb1,Ppm1k,Cav1,Ripk3,Tnf |
| 3.251e-06 | -12.64 | leukocyte homeostasis | biological process | GO:0001776 | 85 | 19 | 20694 | 1406 |
Casp3,Ikbkg,Hif1a,Il6,Ahr,Hcar2,Ripk3,Fas,Lyn,Tnfaip3,Stat5a,Bcl2a1a,Bcl2l11,Ccl2,Pik3cd,Pde4b,Dock10,Pmaip1,Axl |
| 3.251e-06 | -12.64 | production of molecular mediator of immune response | biological process | GO:0002440 | 85 | 19 | 20694 | 1406 |
Atm,Fas,Tlr2,Dennd1b,Nod2,Il18,Batf,Fgl2,Trem1,Sirt1,Icosl,Swap70,H2-Ab1,Pou2f2,Il18rap,Nlrp3,Samhd1,Il12b,Traf3ip2 |
| 3.341e-06 | -12.61 | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | MSigDB lists | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | 1125 | 132 | 15632 | 1249 |
Parp10,Prrg4,Arg2,Ifit2,Slc25a37,Klf6,Arid5a,Ifi209,Tcf4,Oaf,Stat3,Fgl2,Ccng2,Phf6,Arid5b,Inpp1,Ppp2r2a,Dusp6,Psd4,Gja1,Tor1aip1,Cd274,Lcp2,Atp6v1d,Fosb,Ddit4,Degs2,AA467197,Pde7b,Cdkn2d,Pikfyve,Arl4a,Ifi214,P2ry14,Zbtb5,Extl2,Ifi207,Rbl1,Me1,Zc3hav1,Slfn5,Tle3,Itgav,Gpr18,Cited2,Ptpn2,Tor1aip2,Stap1,Cpd,Ptk2,Ptgir,Mmp9,Dnajb4,Itga9,Ifi204,Mthfd2,Orai2,Jak2,Gfpt1,Tax1bp1,H3f3b,Dusp16,Lrrc8c,Atm,Nfkb1,Tnfrsf1b,Vezt,Mov10,Sik3,Mndal,Ifi211,Mcm10,Lif,Pml,Rab19,Jmjd6,Sertad3,Ifi213,Hsph1,Rgs14,Ifi205,Cish,Dennd1b,Egr2,Kdm5b,Lztfl1,Gsr,Ptprj,Traf3ip2,Kcna3,Spata5l1,Slc37a3,Junb,Jarid2,Txn1,Map4k4,Tshz1,Fubp1,Igsf8,Dmwd,Nmi,Ifi208,Stoml1,Dgka,Adora2a,Etv3,Ccnd2,Pttg1,Prdx1,Herc3,Cx3cr1,Tiparp,Kcnj2,Irf4,Myc,Ppp2r5a,Tra2a,Kpna3,Tnfsf4,Tmod3,Dck,Ms4a6d,Sema4a,Gpd2,Pik3cd,Rgs1,Asf1a,Armc8,Irf8,Itgal,Sirt1,Ifi203 |
| 3.344e-06 | -12.61 | ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP | MSigDB lists | ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP | 67 | 18 | 15632 | 1249 |
Map3k8,Il4ra,Ptafr,F11r,Il13ra1,H2-Ab1,Tnfrsf14,Zbp1,Rgs1,Jun,C1rl,Lcp2,Cx3cr1,Klf6,Pde4b,Cd69,H2-Aa,Sat1 |
| 3.344e-06 | -12.61 | SESTO_RESPONSE_TO_UV_C1 | MSigDB lists | SESTO_RESPONSE_TO_UV_C1 | 67 | 18 | 15632 | 1249 |
Sod2,Slc31a2,Nampt,Ifit1bl1,Ifit1bl2,Lcn2,Cnn3,Bnip3,Psma6,Hdac1,Dusp5,Ier2,Pim1,Serpinb2,Tnip1,Tnfaip3,Cdkn1a,Ppp2r2a |
| 3.345e-06 | -12.61 | KIM_WT1_TARGETS_12HR_UP | MSigDB lists | KIM_WT1_TARGETS_12HR_UP | 145 | 29 | 15632 | 1249 |
Junb,Eno2,Ifit1bl2,P4ha1,Gdf15,Tuba4a,Serpine1,Csf1,Ddit4,Htra1,Endod1,Mtdh,Kif3c,Cdc42ep4,Acsl1,Gfpt1,Plat,P4ha2,Ifit1bl1,Hsph1,Lrp4,Mtus1,Rhoq,Cxcl14,Tulp3,Cx3cl1,Plau,Atp2b4,Tle3 |
| 3.453e-06 | -12.58 | TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | MSigDB lists | TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | 356 | 54 | 15632 | 1249 |
Gpc1,Cd34,Rbms2,Mapkapk2,Stxbp1,Egr1,Il4ra,Ccl22,Sdc1,Rapgef5,Nr4a1,Flt1,Rab32,Nfkbia,Jun,Cyfip1,Fos,Gpr18,Tnfaip2,Actb,Fscn1,Prkar2b,Mmp9,Flnb,Csf1,Smpdl3b,Ltbp2,Birc3,Eno2,S100a8,Lcn2,Nos2,Relb,Tnfaip3,Hhex,Traf1,Fabp3,Fgr,Ifi44,Tnc,Rbpms,Dusp1,Cd40,Ikbke,Nfkb2,Vcam1,Gng4,Hp,Scn1b,Tlr1,Btg2,Spint2,Fcgr4,Fosb |
| 3.464e-06 | -12.57 | enzyme activator activity | molecular function | GO:0008047 | 450 | 58 | 20217 | 1400 |
Ranbp2,Apaf1,Elmod2,Dock4,Pdgfb,Tbc1d13,Ahsa1,Irgm2,Mtcp1,Dnajb2,Sipa1l1,Rapgef2,Dnajb4,Tor1aip1,Cox17,Cav1,Psme1,Psme2,Cdc42ep2,Daxx,Rgs1,Dnaja2,Nupr1,Htr2b,Prkce,Bmp2,Cflar,Ccl5,Dtx3l,Lgals9,Cdk5r1,Spry2,Nsmaf,Rin2,Malt1,Dnaja1,Asap3,Rictor,Rgs3,Map2k1,Phactr4,Tank,Tor1aip2,Rgs14,Casp3,Jun,Abr,Dcp1a,Ctsc,Mmp25,Adap2,Arhgap26,Rgcc,Rap1gap2,Tagap,Cdkn1a,Ppp2r5a,Tbc1d1 |
| 3.469e-06 | -12.57 | regulation of alpha-beta T cell proliferation | biological process | GO:0046640 | 37 | 12 | 20694 | 1406 |
Arg2,Il18,Irf1,Cd80,Syk,Cd274,Tnfsf4,Il12b,Tarm1,Tnfrsf14,Ripk2,Lgals9 |
| 3.488e-06 | -12.57 | GSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 153 | 30 | 15632 | 1249 |
Sesn3,Psmb8,Irf7,Pid1,Klf2,Med13,Slpi,Rasgrp1,Snx2,Parp3,Chd9,Adam19,Ap3m2,Fmnl2,Oas3,Rhbdf2,Psmb9,Pde1b,Ctsc,Tapbp,Ccng2,Pigv,Kmo,Calcrl,Pbx1,Tspo,Kif9,Ciita,Rbl1,Enpp4 |
| 3.499e-06 | -12.56 | MyD88-dependent toll-like receptor signaling pathway | biological process | GO:0002755 | 16 | 8 | 20694 | 1406 |
Tnip1,Tlr1,Tlr2,Tlr9,Irak2,Irak3,Myd88,Tlr6 |
| 3.500e-06 | -12.56 | GO_REGULATION_OF_PEPTIDE_TRANSPORT | MSigDB lists | GO_REGULATION_OF_PEPTIDE_TRANSPORT | 234 | 40 | 15632 | 1249 |
Tlr3,Tlr9,Ptger4,Zc3h12a,Ptgs2,Il18,Il12b,Tlr2,Jak2,Cacna1d,Pfkl,Nlgn2,Il1b,H2-Eb1,S100a8,Gja1,Ccl5,Tnfsf14,Il10,Nos2,Nfkbib,G3bp2,Lif,Cd74,Hif1a,Nlrp3,Sphk1,Irs2,Pim3,Prdx1,Slc16a1,Cd38,Tnf,Nfkbia,Psmd10,Itpr1,Serp1,Slc2a1,Prkce,Gpr68 |
| 3.511e-06 | -12.56 | KEEN_RESPONSE_TO_ROSIGLITAZONE_DN | MSigDB lists | KEEN_RESPONSE_TO_ROSIGLITAZONE_DN | 101 | 23 | 15632 | 1249 |
Nupr1,Nfkbiz,Atf3,Arg2,Cd74,Hif1a,Cd14,Cd34,Gadd45b,Dusp1,Sat1,Mmp9,Clec4d,Slfn3,Actb,Cxcl1,Dnajb2,Il1b,Pkp4,Csrp1,Txn1,Hdc,Slfn4 |
| 3.557e-06 | -12.55 | MASSARWEH_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | MASSARWEH_TAMOXIFEN_RESISTANCE_UP | 495 | 69 | 15632 | 1249 |
Fchsd2,Sat1,Rsad2,Acvr1,Abcc5,Usp53,Txnrd1,Bcl6,Mtus1,Swap70,Pbx1,Traf5,Pdgfc,Cd164,Nupr1,Rnd1,Spata13,Scn1b,Sh3bp4,Rapgef2,Vasn,Myo1b,Inpp1,Bambi,Tnfsf10,Glrx,Ptprj,Cd55,Lox,Trib3,Rcan1,Edn1,Gadd45g,Ift57,Cpd,Rin2,Gsdmd,Ezr,Klf3,Rhof,Rnd3,Fas,Ppm1l,Rtp4,Sgms2,Sdc1,Zfp36,Pstpip2,Rap1gap2,Jag1,Rictor,Ccne1,Psat1,Psmb8,Mfap3l,P2ry2,Fam20c,Gfpt1,Arf4,Rbms1,Ppfibp2,H3f3b,Ell2,Il13ra1,Casp7,Dram1,Acsl1,Ier3,Rab20 |
| 3.589e-06 | -12.54 | AKT_UP.V1_UP | MSigDB lists | AKT_UP.V1_UP | 161 | 31 | 15632 | 1249 |
Ccng2,Edn1,Slc2a1,Ifit1bl1,Klf6,Flt1,Ifit2,Hck,Ripk3,Sphk1,Plagl1,Atf3,Plscr1,Plk2,Ifit3,Gch1,Ifit1bl2,Tor3a,Pdk3,Nfil3,Ldlr,Idi1,Plat,Sh3bgrl2,Gpd2,Pdzd11,Ifit3b,Adora2b,Ak4,Cd55,Ptprj |
| 3.589e-06 | -12.54 | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | 161 | 31 | 15632 | 1249 |
Slpi,Rasgrp1,Kctd12,AA467197,Stat4,Mmd,Gch1,Gem,Slc7a2,Serpine1,Rgs1,Dusp5,Mmp9,Socs3,Tnfsf4,Serpinb9,Cp,Egr2,Peli1,Vcan,Chst11,Ets2,Tpst1,Homer1,Timp1,Bmp2,Gda,Egr1,Aim2,Arrdc4,Sphk1 |
| 3.605e-06 | -12.53 | GO_REGULATION_OF_CHEMOKINE_PRODUCTION | MSigDB lists | GO_REGULATION_OF_CHEMOKINE_PRODUCTION | 61 | 17 | 15632 | 1249 |
Il1b,Tlr9,Tlr3,Hmox1,Ripk2,Cd74,Adora2b,Hif1a,Il4ra,Mul1,Mefv,Tlr2,Il6,Tnf,Eif2ak2,Il10,P2ry2 |
| 3.632e-06 | -12.53 | peptidyl-tyrosine phosphorylation | biological process | GO:0018108 | 143 | 26 | 20694 | 1406 |
Eif2ak2,Stat5a,Kdr,Flt1,Syk,Lif,Pdgfb,Map2k4,Map2k1,Hck,Dyrk2,Src,Met,Tyk2,Hk1,Il15,Lyn,Il12rb1,Osm,Jak2,Fgr,Igf1r,Sla,Ptk2,Axl,Pdgfrb |
| 3.651e-06 | -12.52 | GSE360_L_DONOVANI_VS_L_MAJOR_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_L_MAJOR_MAC_DN | 169 | 32 | 15632 | 1249 |
Gch1,Pde4b,Cxcl2,Stat4,Rapgef2,Jag1,Pla2g7,Dusp5,Il12b,Kif3c,Tnfaip2,Tnip1,Nfkb2,Tax1bp1,Cflar,Osbpl3,Il1b,Ptges,Dio2,Plaur,Txnrd1,Ass1,Nfkbia,Dusp1,Ehd1,Rbbp8,Pdpn,Optn,Traf1,Tnfaip3,Plagl2,Relb |
| 3.651e-06 | -12.52 | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 169 | 32 | 15632 | 1249 |
Ifnar1,Plac8,Ehd1,Spsb1,Pnp2,Gclm,Micall2,Dusp4,Ift57,Hspa2,Optn,Cdyl2,Nek6,Upp1,Trim13,Slamf7,Casp4,Tnfsf14,Myo1b,Samsn1,Hivep3,Itga5,Cd55,Fpr1,Pim1,Trib1,Ust,Rgs1,Gtpbp2,Acsl5,Cdkn1a,Il15ra |
| 3.651e-06 | -12.52 | GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_UP | MSigDB lists | GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_UP | 169 | 32 | 15632 | 1249 |
Tle3,Samhd1,Plagl1,Rnf135,Fas,Palld,Rbpms,Glipr2,I830077J02Rik,Bnip3,Rab11fip1,Pnp2,Zyx,Rab32,Casp1,Plaur,Trem1,Prkar2b,Tnfaip2,Sema4a,Spire1,Sema4c,Ppa1,Il13ra1,Eef1e1,Spint2,Samsn1,Hopx,Lap3,P2ry2,4933430I17Rik,Hsd17b12 |
| 3.656e-06 | -12.52 | Toll Like Receptor 4 (TLR4) Cascade | REACTOME pathways | R-MMU-166016 | 93 | 23 | 8608 | 757 |
Map3k8,Peli1,Nfkbia,Nfkbib,Ppp2r1b,Nfkb1,Map2k4,Nod2,Tab2,Fos,Nod1,Irak2,Nfkb2,Mapkapk2,Dusp4,Jun,Dusp6,Ripk2,Irf7,Ikbkg,Cd14,Myd88,Cd180 |
| 3.660e-06 | -12.52 | regulation of anatomical structure size | biological process | GO:0090066 | 557 | 67 | 20694 | 1406 |
P2ry2,Adora2a,Cx3cl1,Tnf,Fchsd2,Sod2,Kdr,Gch1,Tmem123,Rab21,Ezr,Cdc42ep4,Adrb2,Evl,Nck1,Icam1,Dock4,Kat2b,Tmsb10,Carmil1,Sema4c,Edn1,Ifrd1,Gclc,Rac3,Ptk2,Ednrb,Ppp1r15a,Htr2a,Slc12a9,Gclm,Pde5a,Plod3,Tmod3,Ptgs2,Vasp,Hif1a,Ptafr,Pdgfb,Cyfip1,Map2k1,Eif4g2,Hcls1,Sema4a,Adora2b,Dusp5,Plek,Csf3,Cdc42ep2,Whamm,Sema3c,Cd38,Tlr2,Cdk5r1,Spire1,Prkce,Ahr,Myadm,Rictor,Cav1,Htr2b,Gja1,Dbnl,Rap1gap2,Akt3,Sirt1,Swap70 |
| 3.667e-06 | -12.52 | GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_UP | MSigDB lists | GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_UP | 185 | 34 | 15632 | 1249 |
Gfi1,Plcl2,Cacna1d,Adam19,Map3k8,Acsl1,Dyrk2,Fndc3a,Spint2,Met,Ext1,Slc7a5,Phlpp2,Gna15,Serpine1,Slc7a8,Eno2,Tuba4a,Atp2b4,Trp53i11,Sla,Socs1,Sell,Rars,Atf3,Ier2,Nfkbie,Rsad2,Gadd45g,Kcnj2,Fut8,Jun,Cenpe,Ppp6r1 |
| 3.667e-06 | -12.52 | GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_DN | 185 | 34 | 15632 | 1249 |
Abcb1a,Mdm2,Tlk2,Pcx,Cpd,Hsph1,Klf3,Parp8,Itgav,Trmt1l,Spryd7,Ttc39c,Tcf4,Ahsa1,Fbxo4,Lif,Spata13,Hif1a,Socs1,Rab10,Jag1,Slamf9,Eef1e1,Hsd17b12,Lcp2,Acsl5,Vcam1,Tax1bp1,Asf1a,Dcbld2,Zc3h12a,Chic2,Kcna3,Gpr85 |
| 3.676e-06 | -12.51 | GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_DN | MSigDB lists | GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_DN | 177 | 33 | 15632 | 1249 |
Rsad2,Rab32,Nfkbia,Stat5a,Insl6,Atp2b4,Stau1,Cd83,Il4ra,Plk3,Oas1a,Timeless,Flnb,Plscr1,Sema3c,Gna15,Birc3,Map4k4,Trem1,Pfkl,Il15ra,Htr2b,Sp110,Tnfsf10,Trib1,Cacnb3,Ptgs2,Kif3c,Ier3,Slc31a1,Mmp9,Oas1g,Ptgir |
| 3.752e-06 | -12.49 | INGRAM_SHH_TARGETS_DN | MSigDB lists | INGRAM_SHH_TARGETS_DN | 55 | 16 | 15632 | 1249 |
Bambi,Fam102b,Il1rn,Glrx,Daxx,C3,Dram1,Evl,Endod1,Sdc1,Calcrl,Tgfbi,Slpi,Tyk2,Vcan,Ccne1 |
| 3.752e-06 | -12.49 | PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN | MSigDB lists | PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN | 55 | 16 | 15632 | 1249 |
Psmb10,Tapbpl,Hmgcs1,Psme1,H2-Q7,Psmb6,Tap1,Tap2,Psmb9,H2-Q6,Serp1,H2-Q4,Psmb8,Tapbp,Psma6,Psme2 |
| 3.759e-06 | -12.49 | SWEET_KRAS_TARGETS_UP | MSigDB lists | SWEET_KRAS_TARGETS_UP | 74 | 19 | 15632 | 1249 |
Evl,Palld,Tgfbi,Acvr1b,Map3k8,Col4a2,Adam19,Atp2b4,Pmepa1,Dnajb2,Junb,Gadd45b,P4ha2,Itgav,Ccl12,Tagln,Flrt2,Serpine1,Jun |
| 3.761e-06 | -12.49 | YOSHIMURA_MAPK8_TARGETS_DN | MSigDB lists | YOSHIMURA_MAPK8_TARGETS_DN | 348 | 53 | 15632 | 1249 |
Dnaja2,Ptprj,Kif3c,Vcam1,Pgk1,Dio2,Dusp6,Pde4b,Atp6v1d,Sipa1l1,Map2k1,Tor1aip1,Nupr1,Slc30a4,Hsph1,Serp1,Itpr1,C1ra,Cebpd,Acvr1,Cd200,Hmgcs1,Mtdh,Max,Gpd2,Acsl1,Odc1,Ccl4,Ldlr,Clcn7,Jak2,Ltbp2,P4ha1,Psat1,Abtb2,Ankib1,St3gal5,Alas1,Cnn3,Zeb1,Egln3,Jag1,Papss2,Slc16a1,Olr1,Ahr,Flt1,Il6,Myc,Gclm,Edn1,Ankrd24,Sdc2 |
| 3.773e-06 | -12.49 | HTLV-I infection | KEGG pathways | ko05166 | 281 | 49 | 7931 | 713 |
Ikbkg,Pttg1,H2-Ab1,Vcam1,Ccnd1,Myc,Fzd5,Map2k4,H2-Q4,Relb,Slc2a1,Nfkbia,Il2rg,Tnf,H2-Q6,Il15ra,Pik3cd,Zfp36,Itgal,Cd40,Ccnd2,Nfkb2,Il6,Pdgfrb,H2-Eb1,Icam1,Egr1,Il15,Cdkn1a,H2-Q7,H2-T24,H2-T22,Stat5a,Fos,Tspo,Rras2,Ets2,H2-T10,H2-M2,Atf3,H2-Aa,Pdgfb,Akt3,Egr2,Fzd1,Kat2b,Nfkb1,Atm,Jun |
| 3.773e-06 | -12.49 | HTLV-I infection | KEGG pathways | mmu05166 | 281 | 49 | 7931 | 713 |
Cdkn1a,H2-Q7,H2-T24,Nfkb2,Il6,Pdgfrb,H2-Eb1,Egr1,Icam1,Il15,Rras2,H2-T22,Stat5a,Fos,Tspo,H2-M2,Atf3,H2-Aa,Ets2,H2-T10,Egr2,Kat2b,Fzd1,Nfkb1,Atm,Jun,Pdgfb,Akt3,Myc,Fzd5,H2-Ab1,Ikbkg,Pttg1,Vcam1,Ccnd1,Slc2a1,Map2k4,H2-Q4,Relb,H2-Q6,Il15ra,Pik3cd,Nfkbia,Il2rg,Tnf,Ccnd2,Zfp36,Cd40,Itgal |
| 3.850e-06 | -12.47 | programmed cell death involved in cell development | biological process | GO:0010623 | 12 | 7 | 20694 | 1406 |
Il1b,Il1a,Kitl,Casp2,Slc4a7,Casp4,Dnase1l3 |
| 3.850e-06 | -12.47 | cellular response to interferon-alpha | biological process | GO:0035457 | 12 | 7 | 20694 | 1406 |
Myc,Ifit2,Axl,Ifit3,Ifnar1,Ifit1,Ifi204 |
| 3.860e-06 | -12.46 | negative regulation of cytokine-mediated signaling pathway | biological process | GO:0001960 | 50 | 14 | 20694 | 1406 |
Ptpn2,Irak3,Il1rn,Samhd1,Parp14,Stap1,Nlrc5,Il6,Rabgef1,Adar,Ccl5,Mul1,Cav1,Rffl |
| 3.870e-06 | -12.46 | negative regulation of MAPK cascade | biological process | GO:0043409 | 170 | 29 | 20694 | 1406 |
Igf1r,Dnaja1,Dusp16,Errfi1,Tnip1,Uchl1,Lyn,Spry2,Cav1,Psmd10,Aida,Dusp4,Irak3,Ptpn2,Rgs14,Spred3,Il1b,Lif,Spred1,Dusp1,Dusp6,Dusp8,Phlpp1,Hsph1,Dusp5,Ezr,Atf3,Dusp2,Ptprj |
| 3.919e-06 | -12.45 | positive regulation of phosphatidylinositol 3-kinase signaling | biological process | GO:0014068 | 71 | 17 | 20694 | 1406 |
Sirt1,Csf3,Il18,Angpt1,Pdgfrb,Pdgfc,Hcls1,Ptk2,Flt1,Kdr,Jak2,Pdgfb,Igf1r,Fgr,Tnf,Ccl5,Osm |
| 3.940e-06 | -12.44 | regulation of monocyte chemotaxis | biological process | GO:0090025 | 26 | 10 | 20694 | 1406 |
Slamf8,Dusp1,Ccl2,Cxcl10,Ccr1,Pla2g7,Fpr2,Lyn,Serpine1,Ccl5 |
| 4.007e-06 | -12.43 | GSE12366_NAIVE_VS_MEMORY_BCELL_UP | MSigDB lists | GSE12366_NAIVE_VS_MEMORY_BCELL_UP | 154 | 30 | 15632 | 1249 |
Mmd,Pde7b,Birc3,4930523C07Rik,Myadm,Dusp6,Plekha2,Gca,Pkp4,Cd200,Ttc39b,Parp14,Edn1,Abcb1a,Il6,Ifi44,Prkce,Batf2,Ogfrl1,Cept1,Treml2,Ddhd1,Tpst1,Gnb4,Cd83,Sla,Gng11,Aff1,Dnase1l3,Il4ra |
| 4.043e-06 | -12.42 | SAFFORD_T_LYMPHOCYTE_ANERGY | MSigDB lists | SAFFORD_T_LYMPHOCYTE_ANERGY | 81 | 20 | 15632 | 1249 |
Casp4,Gch1,Dusp6,Gadd45b,Jarid2,Etv6,Adora2a,Stx11,Rnf19a,Mmd,Egr2,Csf1,Irf4,Bnip3,Nr4a3,Ier3,Adora2b,Notch1,Slc29a3,Clec4e |
| 4.064e-06 | -12.41 | extrinsic apoptotic signaling pathway | biological process | GO:0097191 | 94 | 20 | 20694 | 1406 |
Tnfrsf1b,Bcl2a1a,Bcl2l11,Il18,Lcn2,Casp8,Pml,Casp2,Il1b,Tlr3,Jak2,Itgav,Acvr1b,Bcl2a1b,Inhba,Kitl,Bcl2a1d,Tnf,Il1a,Fas |
| 4.095e-06 | -12.41 | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_DN | 194 | 35 | 15632 | 1249 |
Glrx,Actb,Bcl2a1a,Clic4,Adam19,Serpinb9,Casp7,Hk2,Il18rap,Reps1,Plscr1,Hopx,Casp4,Gem,Snx10,Txn1,Ccl5,Tnfrsf1b,Mdfic,Prdx1,Batf,Pttg1,Itga4,Prdm1,H2-Q7,Errfi1,Cox17,Bcl2a1d,Rhoq,Carhsp1,H2-Q6,H2-Q4,Bcl2a1b,Casp1,Cst7 |
| 4.103e-06 | -12.40 | ENK_UV_RESPONSE_EPIDERMIS_UP | MSigDB lists | ENK_UV_RESPONSE_EPIDERMIS_UP | 261 | 43 | 15632 | 1249 |
Oasl1,Pim2,Cacnb3,Fscn1,Polr2g,Sp110,Vrk2,Map4k4,S100a8,Adap2,Irf7,Ampd3,Plscr1,Pdss1,Pdlim7,Csf1,Procr,Stx6,Hk2,Wars,Nupr1,Il4ra,Gmppb,Upp1,Slc16a1,Gys1,Lipg,Rras2,Dnase1l3,Me1,Klf7,Psip1,Dhrs9,Srm,Zyx,Slc2a1,Carhsp1,Gclm,Bnip3,Tnc,Stat3,Ccng2,Hdac1 |
| 4.104e-06 | -12.40 | acute inflammatory response | biological process | GO:0002526 | 64 | 16 | 20694 | 1406 |
Il6,Cxcl1,Saa3,Serpinb9,Nupr1,Il1a,Icam1,Fcgr1,Plscr1,Trem1,Stat3,Hp,Acvr1,Il1rn,Il1b,Tnfsf4 |
| 4.106e-06 | -12.40 | regulation of macrophage activation | biological process | GO:0043030 | 57 | 15 | 20694 | 1406 |
Stap1,Tlr6,Sphk1,Atm,Cd200,Cx3cl1,Il4ra,Slc7a2,Thbs1,Nr1h3,Ldlr,Ctsc,Il10,Lgals9,Cst7 |
| 4.139e-06 | -12.39 | KEGG_GRAFT_VERSUS_HOST_DISEASE | MSigDB lists | KEGG_GRAFT_VERSUS_HOST_DISEASE | 38 | 13 | 15632 | 1249 |
H2-Aa,Il6,Tnf,H2-Eb1,H2-Q4,H2-Q6,Cd86,Cd80,Il1b,H2-Q7,H2-Ab1,Fas,Il1a |
| 4.139e-06 | -12.39 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN | 38 | 13 | 15632 | 1249 |
Irak2,Ccl4,Cd80,Hmox1,Kdm6b,Traf1,Tnfsf8,Zfp36,Inhba,Ccl12,Ccr1,Slc25a37,Serpine1 |
| 4.150e-06 | -12.39 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_DN | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_DN | 186 | 34 | 15632 | 1249 |
Tmem123,Adam19,Plat,Lrrc8c,Agpat4,Socs3,Hmox1,Ripk2,Chic2,H2-Aa,Antxr1,Stx11,Mmp13,Ankib1,Ccr1,Cd86,Mdfic,Rhoc,Tnfaip3,Rgs3,Spred1,Prdm1,Malt1,Plk3,Ubash3b,F11r,Rai14,Pnp2,Cers6,Itgav,Slc7a11,Klf6,Nfkbia,Parp8 |
| 4.150e-06 | -12.39 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP | 186 | 34 | 15632 | 1249 |
Icam1,Zfp281,Traf1,Gbp3,Sell,Ppm1l,Cd83,Swap70,Jun,Ets2,Gadd45b,Src,Axl,Treml2,Phlpp1,Fgl2,Cish,Itgb8,Rcn1,Cxcl10,Rab20,Mthfd2,Fam53c,Frmd6,Pmepa1,Cacna1d,Adam19,Ldlr,Il10,Lad1,P4ha1,Kctd12,Cxcl2,H2-Aa |
| 4.150e-06 | -12.39 | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_UP | 186 | 34 | 15632 | 1249 |
Aim2,Evl,Usp25,Rab19,Zfp281,Sell,Dtwd1,Crim1,Ifit2,Casp3,Il6,Samd9l,Hmgcs1,Mtdh,Ptger4,Egr3,Filip1l,Dusp5,Phf6,Rcsd1,Map3k8,Fam111a,Zcchc2,Inpp1,Asf1a,Pkp4,Vrk2,Glrx,Slc4a7,Psmb8,Dcun1d3,Samsn1,Phlda1,Parp12 |
| 4.150e-06 | -12.39 | positive regulation of small molecule metabolic process | biological process | GO:0062013 | 144 | 26 | 20694 | 1406 |
Stat3,Dyrk2,Src,Map2k1,Pla2g4a,Adora2b,Hif1a,Ptafr,Pdgfb,Ptger4,Ptgs2,Tnf,Nos2,Sirt1,Ptpn2,Htr2a,Myc,Nr1h3,Il1b,Acsl5,Pid1,Nr4a3,Prkce,Irs2,Kat2b,Nfkb1 |
| 4.150e-06 | -12.39 | positive regulation of JNK cascade | biological process | GO:0046330 | 144 | 26 | 20694 | 1406 |
Nod1,Nod2,Tlr3,Tlr6,Edn1,Nox1,Gadd45b,Il1b,Il1rn,Gadd45g,Mlkl,Fzd5,Mul1,Ripk2,Il1a,Mdfic,Tnf,Mapkbp1,Syk,Traf2,Fcgr2b,Map2k4,Rasgrp1,Tlr9,Map4k4,Myd88 |
| 4.159e-06 | -12.39 | GSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_DN | 170 | 32 | 15632 | 1249 |
Fos,Mafk,Cpd,Ift57,Irf4,Rab21,Tgs1,Icam1,Hif1a,Traf1,Mapkapk2,Crim1,Relb,Plagl2,Cd83,Rrs1,Ppp1r15b,Usp12,Stx11,Btg2,Ksr1,Csf1,Phlpp2,Slc7a5,Arl5b,Map3k8,Serpinb9,Smox,Pim2,Nfil3,Ppp2r2a,Clcf1 |
| 4.173e-06 | -12.39 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_DN | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_DN | 178 | 33 | 15632 | 1249 |
Tnfaip3,Aff1,Atp2b4,Klf7,Gng11,P2ry14,St3gal6,Dmxl2,Hhex,Hlx,Cers6,Scarf1,Rsad2,Ifi44,Nr3c1,Ets2,Ankrd17,Itpr1,Gypc,Acsl1,Il2rg,Cacnb3,Traf3ip2,Slc31a1,Itga5,Tnfsf4,Uba7,Plscr1,Lcp2,Tuba4a,Map4k4,Rgl1,Pde4b |
| 4.173e-06 | -12.39 | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | 178 | 33 | 15632 | 1249 |
Pik3cd,Ms4a6d,Tgfbi,Tnfsf10,Plcl2,Rnaset2b,Tor3a,Slc12a9,4930523C07Rik,Lmo4,Klf2,Rnaset2a,Piezo1,Zfp36,Uba7,Rap1gap2,Itga4,Sell,Cd74,Myd88,Samhd1,Gbp2,Hk3,Cx3cr1,Parp8,P2ry13,Csf3r,Cd302,Fos,Ly75,Ikzf1,Cebpd,Fgl2 |
| 4.183e-06 | -12.38 | positive regulation of nitric-oxide synthase biosynthetic process | biological process | GO:0051770 | 21 | 9 | 20694 | 1406 |
Tlr9,Stat1,Jak2,Kdr,Ccl2,Nod2,Nampt,Map2k4,Tlr2 |
| 4.211e-06 | -12.38 | LIAN_LIPA_TARGETS_6M | MSigDB lists | LIAN_LIPA_TARGETS_6M | 68 | 18 | 15632 | 1249 |
Cxcl1,Tnfaip2,Rgs1,Clec4e,Hmox1,Clec4d,Fcgr2b,Fabp7,Igsf6,Slc15a3,Mmp13,Pla2g7,Ccr1,Clec4n,Gdf15,Marco,Spic,Msr1 |
| 4.245e-06 | -12.37 | HELLER_SILENCED_BY_METHYLATION_DN | MSigDB lists | HELLER_SILENCED_BY_METHYLATION_DN | 95 | 22 | 15632 | 1249 |
Myc,Ddit4,Phgdh,Maff,Wars,Ifrd1,Slc7a11,Gdf15,Crbn,Hsph1,Psat1,Hspa1a,Ppp1r15a,Asns,Thbs1,Ppfibp1,Olr1,Hmox1,Atf3,Adrb2,Dnajb4,Trib3 |
| 4.302e-06 | -12.36 | NABA_SECRETED_FACTORS | MSigDB lists | NABA_SECRETED_FACTORS | 305 | 48 | 15632 | 1249 |
Tnfsf8,Tnf,Insl6,Crlf3,Bmp2,Pdgfc,Ifna2,Ccl3,Lif,Il1a,Pdgfb,Ifna6,Tnfsf15,Csf3,Inhba,Cxcl2,Gdf15,Ccl5,Osm,Il1rn,Cxcl1,Kitl,Tnfsf10,Vegfc,Pf4,Il1b,Il18,Cxcl10,Il12b,Ccl2,Il6,Cxcl14,Ifnb1,Ifna5,Ccl12,Ifna1,Il15,Angpt1,Ccl22,Cx3cl1,Csf1,S100a8,Tnfsf14,Il10,Clcf1,Ccl4,Tnfsf4,Ebi3 |
| 4.372e-06 | -12.34 | cysteine-type endopeptidase activity involved in apoptotic process | molecular function | GO:0097153 | 12 | 7 | 20217 | 1400 |
Cflar,Casp8,Casp2,Casp4,Casp1,Casp3,Casp7 |
| 4.372e-06 | -12.34 | 2'-5'-oligoadenylate synthetase activity | molecular function | GO:0001730 | 12 | 7 | 20217 | 1400 |
Oas3,Oasl2,Oas1b,Oas1a,Oas2,Oasl1,Oas1g |
| 4.377e-06 | -12.34 | cellular metal ion homeostasis | biological process | GO:0006875 | 571 | 68 | 20694 | 1406 |
Gna15,Rmdn3,Lpar1,Hif1a,Cxcl10,1600014C10Rik,Tmem178,Ero1l,Xcr1,Hap1,Fpr2,Lcn2,Prnp,Cacnb3,Slc39a13,Cd38,Mt1,Prkce,Slc31a2,Hmox1,Gpr18,Cxcl3,Cav1,Jak2,Itpr1,Htr2b,Gja1,Itgav,Slc39a4,Slc31a1,Marcksl1,Slc39a14,Il1b,Grina,Swap70,Ccl3,P2ry2,Mt2,Cx3cl1,Cxcl1,Cacna1d,Kdr,Cmklr1,Ptger4,Atp2b4,Cp,Sco1,Ccr1,Pml,Cx3cr1,Ccl2,Gpr35,Slc30a1,Adrb2,Slc9a1,Cxcl2,Ccl5,Edn1,Ccrl2,Cd40,Atp13a1,Ptgir,Ccr3,Fpr1,Ednrb,Htr2a,Myc,Bnip3 |
| 4.420e-06 | -12.33 | positive regulation of interleukin-8 production | biological process | GO:0032757 | 44 | 13 | 20694 | 1406 |
Ptger4,Tlr3,Tnf,Ddx58,Tlr2,Serpine1,Nod2,Cd14,Il18,Myd88,Tlr9,Il1b,Tlr1 |
| 4.420e-06 | -12.33 | negative regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043124 | 44 | 13 | 20694 | 1406 |
Casp8,Rhoh,Optn,Hdac1,Zc3h12a,Sirt1,Tank,Tnfaip3,Nfkbid,Tnip1,Mapkbp1,Tnip3,Stat1 |
| 4.449e-06 | -12.32 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP | 147 | 29 | 15632 | 1249 |
Ptprj,Socs3,Kcna3,Pf4,Junb,Map4k4,Ddit4,Btg2,Rap1gap2,Maff,Itga4,Rnf139,Kat2b,Ubash3b,Mpp7,Irs2,Klf7,Tnfaip3,Samhd1,Parp8,Gadd45b,Dusp1,Pik3r5,Dhrs9,Otud1,Fos,Cited2,Sat1,Tnfsf8 |
| 4.449e-06 | -12.32 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | 147 | 29 | 15632 | 1249 |
Tnfaip3,Plau,Cd34,Nlrp3,Nr1h3,Calcrl,Ubash3b,Abr,Edn1,Ptpn2,Spn,Cx3cr1,Plaur,Plat,Serpinb2,Il12b,Adrb2,Mefv,Zc3h12a,Socs3,Ptger4,Smpdl3b,Pdgfb,Serpine1,Il10,Gja1,Nfkb1,Tnfrsf1b,Rabgef1 |
| 4.453e-06 | -12.32 | GO_POSITIVE_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS | 23 | 10 | 15632 | 1249 |
Il1b,Tlr3,Tlr9,Tnf,Il18,Sphk1,Tlr2,Il12b,Ptgs2,Tnfsf14 |
| 4.453e-06 | -12.32 | PID_NFKAPPAB_CANONICAL_PATHWAY | MSigDB lists | PID_NFKAPPAB_CANONICAL_PATHWAY | 23 | 10 | 15632 | 1249 |
Tnfaip3,Nod2,Ripk2,Ikbkg,Nfkb1,Nfkbia,Malt1,Atm,Tnf,Birc2 |
| 4.575e-06 | -12.29 | WIERENGA_STAT5A_TARGETS_GROUP1 | MSigDB lists | WIERENGA_STAT5A_TARGETS_GROUP1 | 117 | 25 | 15632 | 1249 |
Gbp3,Arl4a,Il4ra,Pim1,Tulp3,Trib3,Dusp5,Myo10,Tle3,Nod1,Samsn1,Plekha4,Cst7,Slc25a37,P4ha2,Hspa2,Il18rap,Vasn,Sh3bp4,Il4i1,Cish,Phlda1,Bbx,St3gal5,Ddit4 |
| 4.586e-06 | -12.29 | Viral carcinogenesis | KEGG pathways | mmu05203 | 228 | 42 | 7931 | 713 |
H2-Q6,Casp8,Traf5,H2-M2,Traf2,Pik3cd,Traf1,Irf7,Stat3,Ccne1,Nfkbia,H2-T10,Syk,Ccr3,Kat2b,Rbl1,Egr2,Jun,Ccnd2,Sp100,Nfkb1,Src,H2-Q7,Cdkn1a,Hdac1,H2-T24,Ubr4,Rel,Eif2ak2,Ccnd1,Nfkb2,Ikbkg,C3,Lyn,Egr3,Pmaip1,Stat5a,H2-T22,Casp3,Mdm2,H2-Q4,Mapkapk2 |
| 4.586e-06 | -12.29 | Viral carcinogenesis | KEGG pathways | ko05203 | 228 | 42 | 7931 | 713 |
H2-Q4,Mapkapk2,Mdm2,Casp3,Stat5a,H2-T22,Egr3,Pmaip1,Lyn,C3,Ikbkg,Nfkb2,Ccnd1,Eif2ak2,Hdac1,Ubr4,H2-T24,Rel,H2-Q7,Cdkn1a,Src,Sp100,Nfkb1,Jun,Ccnd2,Egr2,Kat2b,Rbl1,Ccr3,Syk,H2-T10,Stat3,Ccne1,Nfkbia,Traf1,Irf7,Pik3cd,Traf2,H2-Q6,Casp8,Traf5,H2-M2 |
| 4.601e-06 | -12.29 | RASHI_RESPONSE_TO_IONIZING_RADIATION_4 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_4 | 62 | 17 | 15632 | 1249 |
Hmgcs1,Ifi214,Ifit3b,Ifi204,Hinfp,Ifi207,Bcl2l11,Ifi213,Ifi209,Mndal,Ifi205,Ifit3,Ifi208,Irgm2,Ifi211,Casp2,Ifi203 |
| 4.601e-06 | -12.29 | ST_FAS_SIGNALING_PATHWAY | MSigDB lists | ST_FAS_SIGNALING_PATHWAY | 62 | 17 | 15632 | 1249 |
Daxx,Bfar,Nfkb2,Il1a,Tpx2,Map2k4,Nfkbil1,Fas,Nfkbie,Met,Casp3,Nfkbib,Traf2,Casp8,Nfkbia,Ezr,Nfkb1 |
| 4.615e-06 | -12.29 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_UP | 195 | 35 | 15632 | 1249 |
Serpinb9,Cacnb3,Cox18,Tmod3,Ptgir,Ell2,Lcn2,Gna15,Ltbp2,S100a8,Egln3,Tmem176a,Etv6,Parp12,Isg20,Isg15,Papss2,Sphk1,Usp18,Cdkn2d,H2-Q7,Tmem176b,Prdm1,Tnfrsf14,Cd14,Cd80,Col4a2,H2-Q6,Tspan3,Ttc39c,Crbn,H2-Q4,Glipr2,Dbnl,Slc15a3 |
| 4.633e-06 | -12.28 | BMI1_DN.V1_UP | MSigDB lists | BMI1_DN.V1_UP | 132 | 27 | 15632 | 1249 |
Tagln,Agrn,Slc2a1,Itgb8,Edn1,Chst11,Ccnd1,Lif,Itga4,Tnfrsf8,Tap1,Fzd5,Slc7a5,Slc2a6,Piezo1,Flnb,Nrp2,Csf1,Bst1,Jag1,Inhba,Itga5,Adrb2,Cd82,Plat,Pmepa1,Vegfc |
| 4.641e-06 | -12.28 | positive regulation of cellular component biogenesis | biological process | GO:0044089 | 506 | 62 | 20694 | 1406 |
Palld,Swap70,Gpsm2,Flrt3,Tlr6,Spire1,Prkce,Ahr,Sdc1,Mpp7,Rictor,Cav1,Csf3,Bcl2l11,Plek,Cdc42ep2,Src,Whamm,Map4k4,Ptprj,Sema4a,Adgrl2,Hap1,G3bp2,Atm,Cyfip1,Piezo1,Wdr43,Vasp,Lpar1,Fscn1,Agrn,Rhoc,Rac3,Gda,Phldb1,Dync1h1,Rhoq,Tmem67,Wars,Edn1,Nlgn2,Fas,Icam1,Rgcc,Flrt2,Carmil1,Met,Cdc42ep4,Ikzf1,Evl,Nck1,Sdc4,Cenpj,Kdr,Syk,Mecp2,Aim2,Cx3cl1,Tnf,Fchsd2,P2ry12 |
| 4.661e-06 | -12.28 | KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION | MSigDB lists | KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION | 75 | 19 | 15632 | 1249 |
Cd74,H2-Ab1,H2-Q7,Psme1,Ifna2,Tap1,Ifna1,Ciita,Hspa1a,Tap2,H2-Q6,H2-Eb1,H2-Q4,Tapbp,Ifna5,Hspa2,Psme2,H2-Aa,Ifna6 |
| 4.661e-06 | -12.28 | ONDER_CDH1_SIGNALING_VIA_CTNNB1 | MSigDB lists | ONDER_CDH1_SIGNALING_VIA_CTNNB1 | 75 | 19 | 15632 | 1249 |
C3,Nupr1,Icam1,Adrb2,Ifih1,Cxcl1,Cd83,Cd82,Tnfaip3,Birc3,Tagln,Ltbp2,Sema3c,Myo1b,Serpine1,Peli1,Vcan,Ccng2,Dock10 |
| 4.661e-06 | -12.28 | MCBRYAN_PUBERTAL_BREAST_6_7WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_6_7WK_DN | 75 | 19 | 15632 | 1249 |
Ifit3b,Sdc1,Pttg1,Palld,Gsta3,Hcar2,Plod2,Bcl6,Ifit3,Timp1,Tagln,Dusp6,S100a8,Ift57,Vcan,Pla2g7,Slpi,Egr2,Tnc |
| 4.666e-06 | -12.28 | cellular response to amyloid-beta | biological process | GO:1904646 | 32 | 11 | 20694 | 1406 |
Igf1r,Tlr6,Vcam1,Icam1,Itga4,Casp4,Adrb2,Prnp,Sirt1,Fpr2,Fcgr2b |
| 4.689e-06 | -12.27 | GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING | 163 | 31 | 15632 | 1249 |
Aebp2,Ifi213,Ets2,Ifi205,Bcl6,Ifi209,Hinfp,Ifi207,Mxd1,Atf3,Hhex,Prdm1,Ifi214,Zfp281,Etv3,Ifi208,Zeb1,Ifi211,Btg2,Etv6,Ifi203,Jdp2,Nfkb1,Jarid2,Dach1,Mndal,Nfxl1,Gfi1,Nfil3,Arid5b,Ifi204 |
| 4.690e-06 | -12.27 | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_UP | 187 | 34 | 15632 | 1249 |
Daxx,Gbp2,Prpf38a,Ciita,Sdc4,Etv3,Tpx2,Fgl2,Mafk,Irgm2,Casp3,Il4i1,Batf2,Zyx,Ccl12,Igf2bp2,Il15ra,Keap1,Vcam1,Kdr,Osgin2,Ptgs2,Itga9,Tlr9,Kpna3,G3bp2,Car13,Etv6,Nfkbib,Gbp7,Rgl1,Tor3a,Pdk3,Ccl5 |
| 4.690e-06 | -12.27 | GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP | MSigDB lists | GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP | 187 | 34 | 15632 | 1249 |
Oas1g,Rcsd1,Nr4a3,Parp11,Acvr1b,Pgk1,Tfec,Vegfc,Epsti1,Dio2,Sesn3,Dach1,Plekha2,Ppm1k,Parp12,Egln3,Etv6,Stat4,Hivep3,Oas1a,Cdkn2d,Csrnp1,Calcrl,Spata13,Herc3,Extl2,Angpt1,Insl6,Src,Slc2a1,Arid5a,Ifi44,Rnf24,Cers6 |
| 4.708e-06 | -12.27 | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN | MSigDB lists | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN | 271 | 44 | 15632 | 1249 |
Gbp2,Malt1,Prdm1,Tab2,Stat3,Fchsd2,Slc25a37,Cst7,Casp1,Mtus1,Tnfsf10,Trafd1,Dusp5,Pde4b,Gch1,Ccl5,Hopx,Tor1aip1,Lcp2,Fubp1,Sgcb,Gng11,Fas,Abcb1a,Optn,Tiparp,Zcchc2,Cflar,Idi1,Rap2c,Ccl4,H3f3b,Gfi1,Dyrk2,Adrb2,Rnf19a,Stat4,Rap1gap2,Hat1,Atm,Birc3,Tnfrsf1b,Mcm9,Casp4 |
| 4.710e-06 | -12.27 | BECKER_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | BECKER_TAMOXIFEN_RESISTANCE_UP | 44 | 14 | 15632 | 1249 |
Irf2,Egr3,Isg15,Arl4a,Cacnb3,Ppp2r2a,Tagln,Eif2ak2,Ifit1bl2,Ifit1bl1,Tspan3,Nmi,Ifi44,Procr |
| 4.731e-06 | -12.26 | GSE3039_CD4_TCELL_VS_B2_BCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_B2_BCELL_UP | 179 | 33 | 15632 | 1249 |
Tnc,Bbx,Arhgap26,Dtnb,Prdx5,Triobp,Nr4a1,Agrn,Spic,Gys1,Enpp4,Olfml3,Tmem176b,Egr1,Plagl1,Fpr2,Cdk5r1,Mpp7,Ube2l6,Btg2,Rap1gap2,Stx11,Uba7,Tuba4a,Ppp1r15a,Fosb,Vcam1,Inpp1,Sp110,Dgkh,Hp,Mmp9,Trib1 |
| 4.731e-06 | -12.26 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_DN | 179 | 33 | 15632 | 1249 |
Ciita,Dcp2,Csrnp1,Pde5a,Dusp4,Rin2,Itgb8,Carhsp1,Prkce,Phgdh,Zyx,Eno1,Hmga1,Slc7a11,Gypc,Src,Hivep2,Pmepa1,Htr2b,Snn,Rgs1,Slamf8,Mob3b,Ptk2,Stx6,Hat1,Met,Alas1,Asns,Cd274,Vezt,Ttc9c,Rabgef1 |
| 4.731e-06 | -12.26 | GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_UP | 179 | 33 | 15632 | 1249 |
P2ry14,Sass6,Arrdc4,Ciapin1,Nck1,Ripk3,Tspo,Zbtb5,Rnd3,Psmb9,Ppp1r14b,Nlrc5,Cxcl14,Gsr,Rin2,Ap3b1,Rai14,Aftph,Il2rg,Cox18,Rcn1,Dck,Ppa1,Traf3ip2,Pcgf5,Tmem123,Rbms1,Osm,Ogfr,Slc13a3,Pla2g7,Eya4,Tmeff1 |
| 4.731e-06 | -12.26 | GSE3982_MAC_VS_NKCELL_UP | MSigDB lists | GSE3982_MAC_VS_NKCELL_UP | 179 | 33 | 15632 | 1249 |
Plaur,Gng12,Acp2,Cdkn1a,Glrx,Siglece,Rgs1,Slc43a3,Trib1,Asb13,Acsl1,Ptk2,Smox,Hmox1,C3,Uchl1,Jag1,Hivep3,Ppp2r3a,Kctd12,Csf1,Ampd3,Tnfsf14,Tor3a,Cd83,Plau,Ccl22,Stxbp1,Kcnj2,Fcgr2b,Cish,Rab11fip1,P4ha2 |
| 4.731e-06 | -12.26 | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_DN | MSigDB lists | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_DN | 179 | 33 | 15632 | 1249 |
Tap1,Ccdc88b,Myd88,Cd83,Kmo,Icam1,Ier2,Dusp4,Cers6,Ccdc86,Egr2,Pnp2,Stat3,Cd40,Ankrd17,Nr4a1,Wdr43,Rcl1,Ccl4,Tmem123,Mob3b,Ebi3,Egr3,Slc39a14,Hivep3,Plscr1,Psme2,Btg2,Rrs1,Nfkb1,Abtb2,Mthfd1l,Nampt |
| 4.733e-06 | -12.26 | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_UP | 171 | 32 | 15632 | 1249 |
Lpar1,Ifi204,Il13ra1,Scyl2,Thbs1,Adam19,Gbp2b,Daam1,Mndal,Serpine1,Myadm,Ifi203,Ifi211,Caml,Ifi208,Ifi214,Atp2b4,Ncoa7,Ifi207,Olfml3,Rnd3,Otud1,Ifi205,Ifi209,Dusp1,Ifi213,Morc3,Tagln,Optn,Ccng2,Samd9l,Cebpd |
| 4.758e-06 | -12.26 | mononuclear cell migration | biological process | GO:0071674 | 38 | 12 | 20694 | 1406 |
Ccl5,Cx3cl1,Ccl3,Ccl7,Pdgfb,Ccl4,Flt1,Ccl9,Ccl12,Ccl8,Ccl22,Ccl2 |
| 4.758e-06 | -12.26 | lymphocyte chemotaxis | biological process | GO:0048247 | 38 | 12 | 20694 | 1406 |
Ccl4,Cxcl10,Ccl3,Ccl7,Cx3cl1,Ccl5,Ccl2,Ccl22,Ccl8,Ch25h,Ccl9,Ccl12 |
| 4.758e-06 | -12.26 | response to amyloid-beta | biological process | GO:1904645 | 38 | 12 | 20694 | 1406 |
Icam1,Igf1r,Vcam1,Tlr6,Fpr2,Fcgr2b,Adrb2,Itga4,Casp4,Mmp9,Sirt1,Prnp |
| 4.758e-06 | -12.26 | regulation of activated T cell proliferation | biological process | GO:0046006 | 38 | 12 | 20694 | 1406 |
Cd86,Il12b,Tnfsf4,Cd274,Prnp,Tnfsf9,Icosl,Il18,Stat5a,Il12rb1,Ripk3,Casp3 |
| 4.758e-06 | -12.26 | platelet-derived growth factor receptor signaling pathway | biological process | GO:0048008 | 38 | 12 | 20694 | 1406 |
Ptprj,Nr4a3,Lox,Rgs14,Pdgfc,Pdgfrb,Jak2,Csrnp1,Tiparp,Plat,Arid5b,Pdgfb |
| 4.797e-06 | -12.25 | Cell surface interactions at the vascular wall | REACTOME pathways | R-MMU-202733 | 101 | 24 | 8608 | 757 |
Angpt1,Lyn,Slc16a3,Slc7a5,Olr1,Sele,Sdc4,Pf4,Slc7a8,Spn,F11r,Cav1,Sdc1,Itga4,Procr,Trem1,Gpc1,Itgal,Sdc2,Itga5,Cd74,Slc7a11,Slc16a1,Sell |
| 4.819e-06 | -12.24 | positive regulation of receptor signaling pathway via STAT | biological process | GO:1904894 | 103 | 21 | 20694 | 1406 |
Hdac1,Il18,Parp14,Il10,Hcls1,Il12b,Notch1,Il6,Ptger4,Cd40,Lif,Jak2,Cenpj,Lyn,Crlf3,Parp9,Osm,Tnf,Ccl5,Il15,Clcf1 |
| 4.862e-06 | -12.23 | HAN_SATB1_TARGETS_UP | MSigDB lists | HAN_SATB1_TARGETS_UP | 351 | 53 | 15632 | 1249 |
Spint2,Inhba,Tnfsf15,Serpine1,Pde4b,Il1b,Plat,Lox,Tgfbi,Ak4,Oas1g,Ccng2,Cebpd,Lztfl1,Sat1,Tnc,1110038F14Rik,Fut8,Tcf4,Psmb9,Mtus1,Casp1,Ifit2,Dusp1,Gbp2,Myo10,Mcmbp,St3gal6,F11r,Lif,Eef1e1,Oas1a,Ccdc25,Ep400,Ifit3,Ccne1,Pmepa1,H3f3b,Agpat4,Fam20c,Ifit3b,Dnajb4,Pcx,Chst11,Il6,Hmga1,Ccl12,Sqstm1,Klf3,Klf7,Slc16a1,Plau,Phip |
| 4.866e-06 | -12.23 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR | 56 | 16 | 15632 | 1249 |
Cdkn1a,Ifi207,Ifi214,Ifi204,Pml,Nupr1,Dyrk2,Ifi203,Sirt1,Ifi208,Ddit4,Ifi211,Ifi209,Mndal,Ifi205,Ifi213 |
| 4.874e-06 | -12.23 | KRIGE_AMINO_ACID_DEPRIVATION | MSigDB lists | KRIGE_AMINO_ACID_DEPRIVATION | 28 | 11 | 15632 | 1249 |
Ddit4,Wars,Cdkn1a,Ccng2,Atf3,Psat1,Slc7a11,Ass1,Ppp1r15a,Asns,Trib3 |
| 4.874e-06 | -12.23 | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION | 28 | 11 | 15632 | 1249 |
Il1b,Cd80,Irf4,Cd83,Il1a,Traf2,Cd86,Ripk2,Malt1,Tnfsf4,Pde4b |
| 4.874e-06 | -12.23 | GO_MYD88_INDEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_MYD88_INDEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 28 | 11 | 15632 | 1249 |
Prkce,Ikbke,Cd14,Tnip3,Casp8,Tank,Irf7,Birc2,Birc3,Tlr3,Ikbkg |
| 4.930e-06 | -12.22 | GO_REGULATION_OF_NITRIC_OXIDE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_NITRIC_OXIDE_BIOSYNTHETIC_PROCESS | 50 | 15 | 15632 | 1249 |
Ptgs2,Icam1,Zc3h12a,Il1b,Atp2b4,Tspo,Jak2,Cd34,Cav1,Il10,Klf2,Ass1,Tnf,Il6,Edn1 |
| 4.982e-06 | -12.21 | DOUGLAS_BMI1_TARGETS_DN | MSigDB lists | DOUGLAS_BMI1_TARGETS_DN | 289 | 46 | 15632 | 1249 |
Rap2c,Clcn7,Stat1,Ifi35,Mtmr14,Cpeb4,Etnk1,Ifit3b,Ccdc25,Oas1a,Birc3,Casp8,Vezt,Ifit3,Slfn5,Nfkbiz,Dcp2,Gadd45g,Optn,Slc7a11,Sqstm1,Ifit1bl1,Nfkb2,Gtpbp2,Elmod2,Oas1g,Herc6,Arl5b,Tbc1d13,Rapgef2,Sesn3,Ifit1bl2,Golga3,Tnfaip3,Mvp,Apaf1,Icam1,Calcrl,Dbnl,Fchsd2,Ccng2,Dhx58,Ifit2,Oas3,Birc2,Psmb9 |
| 5.021e-06 | -12.20 | GO_BIOLOGICAL_ADHESION | MSigDB lists | GO_BIOLOGICAL_ADHESION | 947 | 114 | 15632 | 1249 |
Sema4a,Pik3cd,Azi2,Irf1,Cd200,Tnfsf4,Ebi3,Nlgn2,Tnip1,Siglece,Actb,Itgal,Tnfsf14,Egr1,Ppfibp1,Angpt1,Rnd3,Ifna1,Zyx,Slc7a11,Ccl12,Flrt3,Bcl2l11,Ezr,Cx3cr1,Prkce,Pdpn,Il6,Ccr3,Irf4,Il12b,Clec4d,Tgfbi,Fndc3a,Ptger4,Thbs1,Prkx,Cd86,Scn1b,Antxr1,Ifna6,Sell,Jmjd6,Icam1,Apba1,Rhoh,Malt1,Itga4,Hck,Relb,Ripk3,Cd164,P2ry12,Ifnar1,Axl,Src,Itga9,Itga5,Ccl4,Whamm,Casp8,Vezt,S100a8,Cdk5r1,Cx3cl1,Fpr2,Col18a1,Stxbp1,Fas,Nck1,Olr1,Slamf7,Cd80,Clec4e,Il15,Cd34,Ptpn2,Syk,Itgav,Spn,Scarf1,Ifna5,Ifnb1,Vcan,Ripk2,Il1b,Pkp4,Kitl,Vcam1,Pcdh7,Flrt2,Fzd5,Csrp1,Ccl5,Plek,Ccr1,Igsf9,Stxbp3,Icosl,Nrp2,Psmb10,F11r,Cd74,Ifna2,Batf,Csf3r,Tnf,Rsad2,Treml2,Sele,Tnfsf8,Itgb8,Micall2,Tnc |
| 5.065e-06 | -12.19 | GO_REGULATION_OF_T_HELPER_2_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_T_HELPER_2_CELL_DIFFERENTIATION | 11 | 7 | 15632 | 1249 |
Cd86,Il4ra,Nlrp3,Bcl6,Hlx,Tnfsf4,Il6 |
| 5.065e-06 | -12.19 | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | MSigDB lists | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | 11 | 7 | 15632 | 1249 |
Casp8,Casp4,Casp1,Casp7,Casp2,Casp3,Cflar |
| 5.097e-06 | -12.19 | TAK1 activates NFkB by phosphorylation and activation of IKKs complex | REACTOME pathways | R-MMU-445989 | 26 | 11 | 8608 | 757 |
Nfkbib,Myd88,Tab2,Irak2,Nod1,Nfkb2,Ripk2,Nfkb1,Nod2,Nfkbia,Ikbkg |
| 5.118e-06 | -12.18 | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | 148 | 29 | 15632 | 1249 |
Plac8,Klf3,Bcl2a1b,Mtus1,Mdn1,Irf4,Phgdh,Peli1,Bcl2a1d,Cers6,Marcksl1,Phip,Il4ra,Sell,Pde3b,Klf7,Atm,Ccne1,Sesn3,Map4k4,Ubr4,Ep400,Atxn7l1,Pde7b,Ptk2,Il12b,Bcl2a1a,Abcc1,Snn |
| 5.195e-06 | -12.17 | RIGGINS_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | RIGGINS_TAMOXIFEN_RESISTANCE_DN | 196 | 35 | 15632 | 1249 |
Kif5c,Stat1,Oas1g,Hmgcs1,Arid5b,Tnfsf10,Tmem123,Rbms1,Igf1r,Gja1,S100a8,Nampt,Mfap3l,Lap3,Sema3c,Nmi,Ube2l6,Cnn3,Oas1a,Rapgef2,Palld,Mapkapk2,Ddx60,Ifih1,Isg15,Prnp,Plekha5,Eif2ak2,Cd302,Timp1,Cish,Rai14,Nat2,Cpd,Cebpd |
| 5.197e-06 | -12.17 | Dissolution of Fibrin Clot | REACTOME pathways | R-MMU-75205 | 5 | 5 | 8608 | 757 |
Plaur,Plau,Plat,Serpinb2,Serpine1 |
| 5.205e-06 | -12.17 | MODULE_16 | MSigDB lists | MODULE_16 | 472 | 66 | 15632 | 1249 |
Myc,Ctsc,Cpd,Ccl12,Slc7a11,Ifit1bl1,Spn,Cited2,Zyx,Plau,Hk3,Cdk5r1,Tpx2,Sdc1,Pttg1,Ccnd2,Nfkbib,Slpi,Trip13,Casp2,Hat1,Eef1e1,Smpdl3b,P4ha1,Ikbkg,Ccne1,Tnfrsf1b,S100a8,Gna15,Adam19,Ccl4,Hcls1,Ldlr,Rac3,Mmp9,Ier3,Pnp2,Cst7,Slc16a3,Tnf,Slc2a1,Rbbp8,Sla,Hck,Lif,Ube2e1,Plk3,Fgr,Atp11a,Slc7a5,Nmi,Hap1,Oas2,Psd4,Dusp6,Ccl5,Jarid2,Plek,Ifit1bl2,Lcp2,Asns,Serpinb2,Glrx,Plaur,Mcm6,Il2rg |
| 5.221e-06 | -12.16 | regulation of lipid metabolic process | biological process | GO:0019216 | 338 | 46 | 20694 | 1406 |
Il1a,Tnf,Stat5a,Tspo,Pde3b,Pla2g4a,Gk,Pik3r5,Hcar2,Rubcnl,Egr1,Nod2,Irs2,Rbl1,Igf1r,Fgr,Nr1h3,C3,Fabp3,Pdgfrb,Htr2a,Ptgs2,Flt1,Pdgfb,Ldlr,Pdk3,Bmp2,Fpr2,Adora2b,Src,Nr3c1,Prkce,Nr4a3,Nfkb1,Pcx,Cav1,Lyn,Ppp2r5a,Htr2b,Sphk1,Il1b,Gfi1,Acsl5,Trib3,Sirt1,Ttc39b |
| 5.277e-06 | -12.15 | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP | MSigDB lists | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP | 69 | 18 | 15632 | 1249 |
Fcgr2b,Isg20,Ctsc,Ccl2,Slc15a3,Ccl12,Ccl5,Timp1,Serpine1,Thbs1,Sla,Cd14,Tmem176b,H2-Ab1,C3,Slamf8,Cxcl10,Il4ra |
| 5.277e-06 | -12.15 | GO_POSITIVE_REGULATION_OF_STAT_CASCADE | MSigDB lists | GO_POSITIVE_REGULATION_OF_STAT_CASCADE | 69 | 18 | 15632 | 1249 |
Socs3,Lif,Ptger4,Il12b,Lyn,Il18,Hcls1,Crlf3,Il15,Clcf1,Jak2,Notch1,Ccl5,Osm,Cd40,Il10,Il6,Stat3 |
| 5.295e-06 | -12.15 | GSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 188 | 34 | 15632 | 1249 |
Mthfd1l,Tor3a,Nfkb1,Mcm9,Tap2,Cenpj,Stxbp3,Cxcl2,Crkl,Dnaja2,Tlr2,Fscn1,Ikbke,Slfn9,Adam19,Lacc1,Abcc1,Glrx,Ptges,Parp8,Zmynd15,Ptpn2,Rhbdf2,Parp14,Slfn8,Slc15a3,Batf2,Samd9l,Usp18,Kdm4a,Ifih1,Fbrsl1,Rnf34,Ifit1 |
| 5.358e-06 | -12.14 | GSE30083_SP1_VS_SP2_THYMOCYTE_UP | MSigDB lists | GSE30083_SP1_VS_SP2_THYMOCYTE_UP | 180 | 33 | 15632 | 1249 |
Tnfaip2,Agpat4,Prkar2b,Slc31a1,Trib1,Pdzd11,Cxcl10,Sh3bp4,Hk2,Egln3,Tbc1d13,4933430I17Rik,Eno2,Ccr1,Gna15,Ppp1r15a,Rrs1,Dmwd,Hdc,Pdgfrb,Plk3,Icam1,Ccdc86,Igsf6,Arhgap26,C1ra,Ift57,B3gnt5,Armcx6,Fam43a,Abcc5,Fos,Tcf4 |
| 5.358e-06 | -12.14 | GSE3982_MAST_CELL_VS_BCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_BCELL_UP | 180 | 33 | 15632 | 1249 |
Rsad2,Spry2,Dennd1b,Cyfip1,P4ha2,Cst7,Ccl12,Extl2,St3gal6,Slc30a4,Nupr1,Bst1,Stx11,Hk2,Il18rap,Reps1,Procr,Alas1,Med21,Fcgr4,S100a8,Pkp4,H3f3b,Abcc4,Fscn1,Osbpl3,Slamf8,Rcan1,St7,Sema4c,Hp,Dram1,Atp10a |
| 5.358e-06 | -12.14 | SHEPARD_CRUSH_AND_BURN_MUTANT_UP | MSigDB lists | SHEPARD_CRUSH_AND_BURN_MUTANT_UP | 180 | 33 | 15632 | 1249 |
Jun,Fos,Mrpl52,Gadd45b,Ccng2,Dusp4,Mdm2,Sat1,Egr1,Atf3,Plk3,Magohb,Mcmbp,Bmp2,Pfkfb3,Rrs1,Casp8,Klf2,Rnaset2a,Jdp2,Junb,Pdss1,Noc4l,Btg2,Odc1,Ak4,Rcan1,Ptgs2,Pim1,Mmp9,Dusp5,Vrk2,Rnaset2b |
| 5.358e-06 | -12.14 | GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_DN | MSigDB lists | GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_DN | 180 | 33 | 15632 | 1249 |
Bambi,Slc29a3,Abcc1,Abcc4,Rcl1,Tagap,Ppa1,Slc31a1,Acsl1,Irf1,Ampd3,Reps1,Il12rb1,Pla2g7,Hivep3,Tmem26,Mthfd1l,Itgal,Irf8,Cd83,Tle3,Fgr,Aldh1b1,Icam1,Ubtd2,Slc44a1,Mdn1,Taf4b,Cdyl2,Chst11,Rapgef5,Ezr,Fam43a |
| 5.358e-06 | -12.14 | GSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_UP | MSigDB lists | GSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_UP | 180 | 33 | 15632 | 1249 |
Spsb1,Flt1,Gpr18,Bnip3,Minpp1,Aftph,Ppp2r5a,Ly75,Acvr1,Triobp,Rsad2,Malt1,Ier2,Kat2b,Slc30a1,Bfar,Pde3b,Cd38,Zc3hav1,Junb,Birc3,Itgal,Fabp7,Slc39a14,Usp12,Kdm6b,Pim2,Mppe1,Trib1,Phyh,Trib3,Tax1bp1,Abcc4 |
| 5.358e-06 | -12.14 | GSE14308_TH2_VS_TH1_DN | MSigDB lists | GSE14308_TH2_VS_TH1_DN | 180 | 33 | 15632 | 1249 |
Dhx58,Samd9l,D1Ertd622e,Bcl6,Cited2,Morc3,Pik3r5,Ifnar1,Ctu1,Klf7,Rbl1,Gnb4,Pnpt1,Fam133b,Slco3a1,Aim2,Mxd1,Nfkbid,Bst1,Oas1a,Rap1gap2,Mov10,Sco1,Irf7,Ttc9c,Tor3a,Hsd17b12,Sesn3,Osbpl3,Larp1,Dgkh,Oas1g,Uchl1 |
| 5.377e-06 | -12.13 | GSE36009_UNSTIM_VS_LPS_STIM_DC_DN | MSigDB lists | GSE36009_UNSTIM_VS_LPS_STIM_DC_DN | 172 | 32 | 15632 | 1249 |
Cyth3,Tab2,Relb,Extl2,Swap70,Txnrd1,Zswim4,Gramd1a,Ift57,Cpd,Stk40,Mllt6,Egr2,Clec4d,Gpr85,Mafg,Rcsd1,Acp2,Abcc1,Frmd6,Ppp2r1b,Hcls1,Nfkb2,Lmo4,Jdp2,Tuba4a,Stx6,Hivep3,Sh3bp4,Ppp4r2,St3gal5,Srxn1 |
| 5.377e-06 | -12.13 | GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP | MSigDB lists | GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP | 172 | 32 | 15632 | 1249 |
Rnf139,Prrg4,Prdm1,Upp1,Cd14,Prpf38a,Rgs3,Cd38,Adhfe1,Jun,Slc44a1,Il6,Dbnl,Ntng2,Katna1,Tnc,Dtnb,Mecp2,Slc31a1,Ripk2,Acsl1,Odc1,Irak2,Sh3bgrl2,Snn,Tfec,Map4k4,Cd86,Cd274,Irf8,AA467197,Rapgef2 |
| 5.377e-06 | -12.13 | GO_FC_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_FC_RECEPTOR_SIGNALING_PATHWAY | 172 | 32 | 15632 | 1249 |
Actb,Clec4d,Nr4a3,Map2k4,Lyn,Ptk2,Psmb6,Psme2,Lcp2,Psmb8,Ikbkg,Nfkb1,Hck,Myo10,Fcgr1,Clec4e,Tab2,Fgr,Psmb10,Malt1,Psme1,Nck1,Psma6,Prkce,Psmd10,Psmb9,Cyfip1,Fos,Jun,Nfkbia,Src,Syk |
| 5.377e-06 | -12.13 | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN | 172 | 32 | 15632 | 1249 |
Cd274,Clic5,Slc12a9,Spint2,Parp12,Jag1,Tifa,Pdgfb,Casp7,Cdkn1a,Ccl4,Acsl5,Actb,Arf4,Jun,Txnrd1,P4ha2,Flt1,Sdc2,Dbnl,Cish,Irf4,Irgq,Arrdc4,Socs1,Traf1,Palld,Dnase1l3,Ppfibp1,Ube2f,Sla,Cd83 |
| 5.392e-06 | -12.13 | GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | 520 | 71 | 15632 | 1249 |
Pde3b,Gng11,Ahr,Fas,Phip,Kat2b,Nr1h3,Irs2,Edn1,Prkce,Il6,Ifnb1,Nr4a1,Ccl12,Ass1,Fos,Ptpn2,Jun,Dnaja1,Gfpt1,Jak2,Igf1r,Socs7,Pmepa1,Prkar2b,Ptk2,Max,Hmgcs1,Tnfsf4,Acsl1,Lyn,Slc9a1,Med13,Sirt1,Rnf14,Ccne1,Nfkb1,Il10,Pid1,Cav1,Plod2,Gnb4,Daxx,Notch1,Hif1a,Agtrap,Stat3,Nr3c1,Tnc,Rhoq,Errfi1,Acvr1,Mdm2,Dusp1,Src,Stat5a,Plod3,Gng12,Ptger4,Gng4,Trib3,Nr4a3,Serpinb9,Rab10,Inhba,Fzd1,Junb,Nampt,Asns,Fosb,Atp6v1d |
| 5.444e-06 | -12.12 | Pept_C14 | interpro domains | IPR002398 | 12 | 7 | 19984 | 1430 |
Casp2,Casp3,Cflar,Casp1,Casp4,Casp7,Casp8 |
| 5.444e-06 | -12.12 | 2-5-oligoAdlate_synth_1_dom2/C | interpro domains | IPR018952 | 12 | 7 | 19984 | 1430 |
Oas1a,Oas2,Oas1g,Oas3,Oasl2,Oas1b,Oasl1 |
| 5.444e-06 | -12.12 | 2-5A_synthase | interpro domains | IPR026774 | 12 | 7 | 19984 | 1430 |
Oas1a,Oas2,Oas1g,Oas3,Oasl1,Oas1b,Oasl2 |
| 5.444e-06 | -12.12 | 2-5-oligoAdlate_synth_2_sf | interpro domains | IPR038121 | 12 | 7 | 19984 | 1430 |
Oas1b,Oasl2,Oasl1,Oas3,Oas1g,Oas2,Oas1a |
| 5.444e-06 | -12.12 | CXC_Chemokine_domain | interpro domains | IPR033899 | 12 | 7 | 19984 | 1430 |
Cxcl9,Cxcl1,Cxcl2,Cxcl3,Cxcl10,Cxcl11,Pf4 |
| 5.513e-06 | -12.11 | regulation of protein kinase B signaling | biological process | GO:0051896 | 155 | 27 | 20694 | 1406 |
Il18,Sirt1,Gdf15,Ptk2,Axl,Mtdh,Igf1r,Clcf1,Spry2,Rictor,Osm,Csf3,Gcnt2,Angpt1,Src,Thbs1,Phlpp1,Ptprj,Hcls1,Cx3cr1,F10,Il6,Cx3cl1,Tnf,P2ry12,Mul1,Sesn3 |
| 5.525e-06 | -12.11 | B cell activation | biological process | GO:0042113 | 173 | 29 | 20694 | 1406 |
Ifna4,Ifna2,Ifna5,Atm,Dock10,Cd86,Ptprj,Icosl,Ikzf1,Batf,H2-Ab1,Slamf8,Pik3cd,Ifna6,Clcf1,Ahr,Ifnb1,Tnfaip3,Notch2,Cd40,Hhex,Cd180,Ptpn2,Malt1,Ifna1,Swap70,Plcl2,Pou2f2,Bcl6 |
| 5.666e-06 | -12.08 | CSR_LATE_UP.V1_DN | MSigDB lists | CSR_LATE_UP.V1_DN | 141 | 28 | 15632 | 1249 |
Epsti1,Mob3c,Il1b,Ldlr,Idi1,Adora2b,Dram1,Hmgcs1,Dennd2a,Xaf1,Ube2l6,Btg2,Me1,Tsku,Cdc42ep2,Irs2,Hhex,Nfkbie,Mllt6,Pde5a,Dusp4,Acvrl1,Oaf,Itgb8,Gypc,Ccl12,Sod2,Ass1 |
| 5.691e-06 | -12.08 | OAS1_C | pfam domains | PF10421 | 12 | 7 | 18711 | 1348 |
Oas1a,Oas3,Oasl2,Oas1g,Oas1b,Oasl1,Oas2 |
| 5.704e-06 | -12.07 | GO_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_BIOSYNTHETIC_PROCESS | 19 | 9 | 15632 | 1249 |
Nod2,Edn1,Jak2,Kdr,Tlr2,Ptger4,Nampt,Tlr9,Ccl12 |
| 5.704e-06 | -12.07 | GO_RESPONSE_TO_INTERFERON_BETA | MSigDB lists | GO_RESPONSE_TO_INTERFERON_BETA | 19 | 9 | 15632 | 1249 |
Ifnb1,Xaf1,Ikbke,Plscr1,Pnpt1,Irf1,Aim2,Tlr3,Stat1 |
| 5.704e-06 | -12.07 | GO_RESPONSE_TO_INTERFERON_ALPHA | MSigDB lists | GO_RESPONSE_TO_INTERFERON_ALPHA | 19 | 9 | 15632 | 1249 |
Adar,Oas1a,Ifit2,Eif2ak2,Axl,Ifnar1,Oas1g,Ifit3,Ifit3b |
| 5.842e-06 | -12.05 | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_UP | MSigDB lists | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_UP | 197 | 35 | 15632 | 1249 |
Batf,Rnd3,Cd80,Mvp,Prdm1,Ccnd2,P2ry14,Gbp3,Aldh1b1,Traf1,Gpr35,Bcl2a1d,Dpy19l1,Fam43a,Bcl2a1b,Spryd7,Cd302,Serp1,Slc2a1,Jak2,Bcl2a1a,Gcnt2,Rgs1,Il15ra,Pfkl,Rcan1,Ms4a6d,Il18,Ier3,Procr,Tdrd7,Rgl1,Cd274,Lcp2,Rims3 |
| 5.844e-06 | -12.05 | GO_B_CELL_ACTIVATION | MSigDB lists | GO_B_CELL_ACTIVATION | 126 | 26 | 15632 | 1249 |
Icosl,Ifna6,Pou2f2,Atm,Cd86,Il10,Casp8,Vcam1,Notch2,Clcf1,Plcl2,Pik3cd,Ifnb1,Ifna5,Klf6,Swap70,Cd40,Bcl6,Ptpn2,Ifna1,Batf,Ifna2,Hhex,Itga4,Malt1,Cd180 |
| 5.888e-06 | -12.04 | nervous system development | biological process | GO:0007399 | 2267 | 206 | 20694 | 1406 |
Cflar,Vasp,Jag1,Phgdh,Kdm4a,Il6,Hif1a,Sema4a,Bmp2,Plk2,Lhx2,Nrp2,Cdk5r1,Nr4a3,Casp3,Gja1,Fubp1,Ppp2r3a,Hmga2,Il1b,Tal2,Mdm2,Btg2,Palld,P2ry12,P2ry2,Cx3cl1,Egr2,Kdr,Pikfyve,Casp8,Fcgr2b,Sdc4,Etv5,Katna1,Ift57,Nck1,Met,Mafk,Slc7a5,Zhx2,Rab10,Mosmo,Tmem67,Vcam1,Stxbp3,Ext1,Mark2,Kdm6b,Agrn,Rnd1,Fabp7,Bcl6,Plod3,Slc4a7,Ednrb,Lpar1,Gpc1,Pdgfb,Lif,Dst,Vcan,Lst1,Fpr2,Dock10,Map2k1,Eif4g2,Nr3c1,Sema3c,Src,Stat3,Egr3,Inhba,Crkl,Sphk1,Rap1gap2,Spint2,Flrt3,Jak2,Akt3,Rgs14,Mthfd1l,Tnfrsf1b,Vegfc,Phactr4,Tulp3,Mecp2,Tnc,Kif5c,Sdc2,Ddit4,Evl,Apaf1,Ccl2,Igsf9,Csf1,Ifrd1,Spen,Sipa1l1,Triobp,Ntng2,Dync1i2,Ptk2,Zeb1,Etv6,Rac3,Prag1,Myc,Fzd5,Ier2,Fos,Abr,Mturn,Mmd,Syne2,Nes,Cyfip1,Atm,Casz1,Adgrl2,Rapgef2,Cd38,Kremen1,Osm,Slc7a11,Cav1,Lyn,Klf7,Spire1,Clcf1,Pbx1,Dbnl,Lmo4,Itpr1,Ptch1,Axl,Il15ra,Hhex,Arf4,Sirt1,Fzd1,Sod2,Jun,Tcf4,Ccl3,Tnf,Zswim4,Cited2,Stxbp1,Ccl12,Prdm1,Ikzf1,Irs2,Kat2b,Uchl1,Ccl5,Psd,Igf1r,Mycl,Nlgn2,Pou3f1,C3,Sec24b,Rpgrip1l,Actb,Mul1,Hlx,Lrp4,Scn1b,Mthfr,Hap1,Micall2,Ldlr,Ptprj,Map4k4,B3gnt5,Hsd17b7,Tlr2,Gfi1,Notch1,Scarf1,Zc3h12a,Ehd1,Tspo,Adora2a,Mov10,Plpp3,Kif3c,Cnp,Rab21,S100a8,Cx3cr1,Intu,Ust,Hdac1,Adgrg6,Flrt2,Fas,Lrp8,Socs7,D16Ertd472e,Sema4c,Stap1,Tsku,Clic5,Itga4 |
| 5.971e-06 | -12.03 | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN | 189 | 34 | 15632 | 1249 |
Tpst1,Ets2,Fam43a,P4ha2,Errfi1,Gbp9,Gbp4,Carhsp1,Traf1,Arrdc4,Nck1,Slc30a4,Cd164,Rab3ip,Crim1,Relb,Tap1,Rras2,Col4a2,Lipg,Il10,Degs2,Bst1,Spint2,Btg2,Ddit4,Ms4a6d,Phyh,Dnajb4,Rab20,St3gal1,Ap3m2,Pmepa1,Sh3bgrl2 |
| 5.971e-06 | -12.03 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_DN | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_DN | 189 | 34 | 15632 | 1249 |
Apaf1,Tspo,Pgm1,Atp11a,Il4ra,Aldh1b1,Mcm10,Sele,Hdac1,Ap3b1,Fcgr2b,Klhl25,Eno1,Serp1,Hmga1,Rapgef5,Plaur,Il15ra,Pfkl,Tfec,Cdkn1a,Hsd17b7,Ikbke,Cd300lf,Fam20c,Adora2b,Mafg,Ier3,Map2k4,Ptgir,Itga5,Ldha,Slc13a3,Mfap3l |
| 6.004e-06 | -12.02 | GO_RESPONSE_TO_STEROID_HORMONE | MSigDB lists | GO_RESPONSE_TO_STEROID_HORMONE | 474 | 66 | 15632 | 1249 |
Fos,Cited2,Dnaja1,Nr4a1,Ccl12,Ass1,Ifnb1,Nqo1,Edn1,Pla2g4a,Mmp14,Il6,Sdc1,Nr1h3,Il4ra,Fas,Ahr,Tspo,Il10,Cav1,Casp8,Ptch1,Rnf14,Ccne1,Med13,Adrb2,C3,Socs3,Cdkn1a,Pmepa1,Jak2,Rbbp8,Dusp1,Tnf,Src,Ccnd1,Errfi1,Mecp2,Acvr1,Mdm2,Nr3c1,Stat3,Casp3,Hif1a,Socs1,Sphk1,Daxx,Cd38,Notch1,Pdgfrb,Fosb,Junb,Ccl5,Mmp13,Pdgfb,Ptgs2,Lox,Nr4a3,Serpinb9,Ptafr,Ptger4,Ldha,Hmox1,Il1b,Il1rn,Thbs1 |
| 6.018e-06 | -12.02 | GSE25677_MPL_VS_R848_STIM_BCELL_UP | MSigDB lists | GSE25677_MPL_VS_R848_STIM_BCELL_UP | 157 | 30 | 15632 | 1249 |
Lpcat2,Herc3,Hck,Cd38,Prdm1,Abr,Traf1,Cd180,Myc,Ikzf1,Plac8,Tcf4,Cyfip1,Dse,Cd300lf,Slc29a3,Dusp16,Ptprj,Tlr3,Ptk2,Nrp2,Pla2g7,Tmem26,Ube2e2,Ccr1,Cd86,Asns,Cd274,Zc3h12c,Itgal |
| 6.060e-06 | -12.01 | GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN | MSigDB lists | GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN | 181 | 33 | 15632 | 1249 |
Dusp6,Card6,Slc4a7,Pde4b,Tlr1,Icosl,Trim21,Akt3,Hat1,Rictor,Dyrk2,Cd200,Tlr3,Adrb2,Frmd4a,Rnf145,Tax1bp1,Vcam1,Morc3,Spic,Dusp2,Fchsd2,Spry2,B3gnt5,Dock10,Ccng2,Ogfrl1,Hhex,Sell,Cdk5r1,Kmo,Slamf7,Rras2 |
| 6.060e-06 | -12.01 | GSE17721_LPS_VS_POLYIC_24H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_24H_BMDC_DN | 181 | 33 | 15632 | 1249 |
Atp11b,Rnd3,Pfkfb3,Aldh1b1,Nxf1,Kat2b,Pttg1,Usp25,Hhex,Irf2,Psme1,Tra2a,Egr2,Gpr35,Katna1,Ikzf1,Tmem184b,Sec24b,Epsti1,Kdr,Rap2c,Gca,Rbms1,Nsmaf,Cxcl10,Cacnb3,Fndc3a,Kctd12,Spint2,Sirt1,Psme2,Timeless,Jarid2 |
| 6.060e-06 | -12.01 | GSE40685_NAIVE_CD4_TCELL_VS_TREG_DN | MSigDB lists | GSE40685_NAIVE_CD4_TCELL_VS_TREG_DN | 181 | 33 | 15632 | 1249 |
Rcl1,Ap3m2,Wdr43,Tnip1,Ifit3b,Rac3,Uba7,Xaf1,Oas2,Ext1,Ksr1,Ifit3,Lgals9,Tor3a,Dusp6,Ifit1,Vcpip1,Rbms2,1600014C10Rik,Cyth3,Ddx58,Pgs1,Marcksl1,Lif,Rhoh,Kdm5b,Parp9,Cers6,Tnfsf8,Gadd45b,Hivep2,Spsb1,Trmt1l |
| 6.068e-06 | -12.01 | phosphotransferase activity, alcohol group as acceptor | molecular function | GO:0016773 | 699 | 80 | 20217 | 1400 |
Akt3,Scyl2,Pim3,Tlk2,Pfkfb3,Dyrk2,Grk3,Ptk2,Acvr1,Irak3,Trib1,Ccnd1,Pikfyve,Irak2,Itpkc,Ksr1,Pik3r6,Ccnj,Ripk2,Etnk1,Kdr,Ccne1,Nrp2,Tyk2,Lyn,Prkce,Plk2,Vrk2,Sik3,Dgka,Mmd,Trib3,Mlkl,Pik3cd,Nek6,Hck,Atm,Map3k8,Dgkh,Hk2,Ccl5,Jak2,Map2k4,Map2k1,Met,Hk3,Axl,Papss2,Hk1,Fgr,Ccnd2,Ccng2,Flt1,Gk,Sla,Eif2ak2,Src,Prkx,Fam20c,Mapkapk2,Stk40,Pdgfrb,Prag1,Igf1r,Plk3,Syk,Ripk3,Ikbke,Cdkn1a,Pim1,Map3k6,Sgk3,Pim2,Sphk1,Mark2,Pfkl,Pdk3,Acvrl1,Acvr1b,Map4k4 |
| 6.090e-06 | -12.01 | GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS | MSigDB lists | GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS | 165 | 31 | 15632 | 1249 |
Bcl2l11,Axl,Ptpn2,Bcl6,Tet2,Il6,Casp3,Ikzf1,Prdx5,Fas,Jmjd6,Hif1a,Adar,Prdx1,Tnfaip3,Ripk3,Arid4a,Pde4b,Vps54,Klf2,Tnfsf14,Ampd3,Csf1,Inhba,Tmod3,Rac3,Hmox1,Lyn,Hcls1,Jak2,Hcar2 |
| 6.090e-06 | -12.01 | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_UP | 165 | 31 | 15632 | 1249 |
Ogfrl1,Sat1,Rab21,Dusp2,Otud1,Tet2,Homer1,Bcl6,Aoah,Dusp1,Sqstm1,Tnfaip3,Pfkfb3,Pde3b,Nlrp3,Sirt1,Rnf19a,Akt3,Med13,Zfp36,Atxn7l1,Nampt,Atm,Plaur,Zhx2,Rsbn1,Cflar,Thbs1,Fcho2,Arid5b,Nr4a3 |
| 6.090e-06 | -12.01 | GSE2706_2H_VS_8H_R848_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_R848_STIM_DC_UP | 165 | 31 | 15632 | 1249 |
Ctsc,Il18bp,Dpy19l1,Sqstm1,Csf3r,Plau,Sdc4,Cdc42ep2,Rab3ip,Hvcn1,Egr1,Icam1,Sgms2,Agtrap,Btg2,Tifa,Ccrl2,Maff,Pdk3,Plek,Ahrr,Dcun1d3,C1rl,Gem,Rap2c,Glrx,Kdm6b,Egr3,Tgfbi,Ms4a6d,Ier3 |
| 6.102e-06 | -12.01 | GSE11961_FOLLICULAR_BCELL_VS_PLASMA_CELL_DAY7_UP | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_PLASMA_CELL_DAY7_UP | 173 | 32 | 15632 | 1249 |
Rcl1,Gng12,Pmepa1,Ccl4,Slfn9,Tnfaip2,Mob3b,Mthfd2,Socs3,Maff,Timeless,Sco1,Nos2,Osm,Ahr,Ahsa1,Icam1,Isg15,Ifih1,Mxd1,Nfkbiz,Csrnp1,Cox17,Nfkbie,Mlkl,Slfn8,Slc15a3,Cish,Batf2,Il4i1,Jun,Ehd1 |
| 6.215e-06 | -11.99 | regulation of programmed necrotic cell death | biological process | GO:0062098 | 17 | 8 | 20694 | 1406 |
Peli1,Birc2,Rnf31,Ripk3,Cav1,Birc3,Casp8,Cflar |
| 6.215e-06 | -11.99 | regulation of necroptotic process | biological process | GO:0060544 | 17 | 8 | 20694 | 1406 |
Birc2,Peli1,Rnf31,Ripk3,Casp8,Cflar,Cav1,Birc3 |
| 6.257e-06 | -11.98 | ISHIKAWA_STING_SIGNALING | MSigDB lists | ISHIKAWA_STING_SIGNALING | 8 | 6 | 15632 | 1249 |
Ifnb1,Adar,Irf7,Irf1,Ccl5,Irf2 |
| 6.257e-06 | -11.98 | GALI_TP53_TARGETS_APOPTOTIC_UP | MSigDB lists | GALI_TP53_TARGETS_APOPTOTIC_UP | 8 | 6 | 15632 | 1249 |
Casp4,Cd40,Birc2,Casp8,Birc3,Atm |
| 6.268e-06 | -11.98 | PETROVA_PROX1_TARGETS_DN | MSigDB lists | PETROVA_PROX1_TARGETS_DN | 57 | 16 | 15632 | 1249 |
Gbp2,Tfec,Plau,Prnp,Itga5,Vcan,Il6,Ly75,Mmp14,Pla2g4a,Procr,Serpine1,Tank,Ltbp2,Ccl12,Axl |
| 6.280e-06 | -11.98 | BIOCARTA_HSP27_PATHWAY | MSigDB lists | BIOCARTA_HSP27_PATHWAY | 15 | 8 | 15632 | 1249 |
Daxx,Apaf1,Casp3,Cycs,Il1a,Tnf,Fas,Mapkapk2 |
| 6.280e-06 | -11.98 | NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP | MSigDB lists | NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP | 15 | 8 | 15632 | 1249 |
Ccl12,Lif,Lox,Timp1,Gna15,Rab21,Plau,Bst1 |
| 6.280e-06 | -11.98 | GO_CHRONIC_INFLAMMATORY_RESPONSE | MSigDB lists | GO_CHRONIC_INFLAMMATORY_RESPONSE | 15 | 8 | 15632 | 1249 |
Thbs1,Vcam1,Ptges,Il1b,Ccl5,Gja1,Tnf,S100a8 |
| 6.338e-06 | -11.97 | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS | 45 | 14 | 15632 | 1249 |
Csf3,Slc9a1,Tnfsf14,Tnf,Il1b,Hcls1,Ddx58,Ptgs2,Tlr2,Il12b,Sphk1,Il18,Tlr3,Tlr9 |
| 6.338e-06 | -11.97 | GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | 45 | 14 | 15632 | 1249 |
Csf1,Gpr68,Tnf,Ccr1,Ccl5,Fos,Jun,Casp8,Hcls1,Kitl,Pf4,Lif,Trib1,Il12b |
| 6.396e-06 | -11.96 | positive regulation of B cell activation | biological process | GO:0050871 | 81 | 18 | 20694 | 1406 |
Clcf1,Stat5a,Il2rg,Irs2,Nod2,Bst1,Il6,Cd40,Syk,Tnfsf4,Cdkn1a,Cd74,Mmp14,Peli1,Bcl6,Cd38,Prdm1,Tlr9 |
| 6.449e-06 | -11.95 | cellular response to vascular endothelial growth factor stimulus | biological process | GO:0035924 | 39 | 12 | 20694 | 1406 |
Egr3,Pdgfrb,Nrp2,Nr4a1,Notch1,Mapkapk2,Flt1,Kdr,Sphk1,Pdgfb,Vegfc,Spry2 |
| 6.467e-06 | -11.95 | response to transforming growth factor beta | biological process | GO:0071559 | 130 | 24 | 20694 | 1406 |
Acvr1,Bmp2,Pml,Zyx,Src,Ccl2,Col4a2,Gcnt2,Acvrl1,Apaf1,Nr3c1,Fos,Jun,Acvr1b,Bambi,Cited2,Ptk2,Sirt1,Dcp1a,Cav1,Serpine1,Crkl,Igf1r,Fut8 |
| 6.529e-06 | -11.94 | regulation of lymphocyte migration | biological process | GO:2000401 | 59 | 15 | 20694 | 1406 |
Crkl,Cxcl14,Cxcl10,Ccl4,Lrch1,Tnfrsf14,Tnfsf14,Cd200,Ccl5,Ripk3,Itga4,Spn,Lgals9,Ccl12,Tnfsf4 |
| 6.529e-06 | -11.94 | alpha-beta T cell differentiation | biological process | GO:0046632 | 59 | 15 | 20694 | 1406 |
Sema4a,Il12b,Tnfsf8,Gadd45g,Spn,Irf4,Batf,Stat3,Irf1,Relb,Rsad2,Gpr18,Il6,Syk,Ptger4 |
| 6.571e-06 | -11.93 | cellular response to virus | biological process | GO:0098586 | 33 | 11 | 20694 | 1406 |
Zc3h12a,Bcl2l11,Ago3,Lgals9,Zc3hav1,Ifih1,Ddx58,Ikbke,Adar,Ifnb1,Irgm2 |
| 6.571e-06 | -11.93 | positive regulation of leukocyte apoptotic process | biological process | GO:2000108 | 33 | 11 | 20694 | 1406 |
Rapgef2,Myc,Pik3cd,Sirt1,Il10,Cd274,Lyn,Nfkbid,Ccl5,Hcar2,Nr4a3 |
| 6.578e-06 | -11.93 | COATES_MACROPHAGE_M1_VS_M2_UP | MSigDB lists | COATES_MACROPHAGE_M1_VS_M2_UP | 70 | 18 | 15632 | 1249 |
Rcn1,Tgfbi,Filip1l,Marcksl1,Crim1,Gda,Gnb4,P2ry13,Marco,Msr1,Gja1,Tor3a,Eno2,Axl,Cxcl14,Ogfrl1,H2-Aa,Rab10 |
| 6.578e-06 | -11.93 | BURTON_ADIPOGENESIS_2 | MSigDB lists | BURTON_ADIPOGENESIS_2 | 70 | 18 | 15632 | 1249 |
Ptges,Samhd1,Clic4,Sphk1,Sdc1,Itga5,St3gal1,Rhou,Fgl2,Prkce,Srxn1,Serp1,Timp1,Srm,Gja1,Map3k6,Spsb1,Hsph1 |
| 6.623e-06 | -11.92 | regulation of macroautophagy | biological process | GO:0016241 | 105 | 21 | 20694 | 1406 |
Nod2,Irgm2,Sesn3,Nod1,Ripk2,Tlr2,Hmox1,Nupr1,Larp1,Hif1a,Ikbkg,Kdr,Pikfyve,Trim13,Pim2,Chmp4b,Adrb2,Optn,Bnip3,Sirt1,Irgm1 |
| 6.636e-06 | -11.92 | Apoptosis signaling pathway | Lipid Maps pathways | Apoptosis | 74 | 29 | 416 | 80 |
Pik3cd,Ikbkg,Cflar,Tnfsf10,Prkx,Myd88,Birc3,Nfkb2,Irak3,Fas,Nfkbib,Casp3,Akt3,Atm,Irak2,Relb,Nfkbie,Nfkb1,Pik3r5,Nfkbia,Apaf1,Tnf,Prkar2b,Il1a,Cycs,Casp7,Traf2,Rel,Casp8 |
| 6.709e-06 | -11.91 | MODULE_521 | MSigDB lists | MODULE_521 | 34 | 12 | 15632 | 1249 |
S1pr2,Csf3,Csf1,Edn1,Il6,Timp1,Cd86,Flt1,Nampt,Vegfc,Tnfsf4,Lif |
| 6.799e-06 | -11.90 | DARWICHE_PAPILLOMA_RISK_HIGH_UP | MSigDB lists | DARWICHE_PAPILLOMA_RISK_HIGH_UP | 127 | 26 | 15632 | 1249 |
Pfkl,Fam162a,Esd,Il1b,Pgk1,Cmpk2,Pmepa1,Ldha,Slpi,Jag1,Txn1,S100a8,Cacybp,Plekha4,Samhd1,Rhoh,Lif,Icam1,Cx3cl1,Gclm,Axl,Srm,Spic,Traf2,Mgat1,Eno1 |
| 6.846e-06 | -11.89 | GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP | 182 | 33 | 15632 | 1249 |
Rnaset2a,Dusp6,P4ha1,Kctd12,Dgka,Ampd3,Zeb1,Cnn3,Nr4a3,Max,Dnajb2,Rnaset2b,Igf1r,Ikbke,Znrf1,Ets2,Tcf4,Abcc5,Spsb1,Ncoa5,Peli1,Slc44a1,Myc,Mdn1,Sell,Il4ra,Ccnd2,Zfp281,Tlr6,Evl,Notch1,Rab3ip,Crlf3 |
| 6.846e-06 | -11.89 | GSE21380_NON_TFH_VS_TFH_CD4_TCELL_DN | MSigDB lists | GSE21380_NON_TFH_VS_TFH_CD4_TCELL_DN | 182 | 33 | 15632 | 1249 |
Armcx6,Plac8,Cdyl2,Hspa2,Ccng2,Rsad2,Dhx58,Ikzf1,Ifi44,Top3a,Trim12c,Rtp4,Dmxl2,Marcksl1,Aim2,Ifit1,Pbx1,Adar,Lcp2,Irf7,Plod2,Plek,Gch1,Sesn3,Ccdc25,Oas2,Trim14,Parp11,Ddx4,Tagap,5430427O19Rik,Gca,Chd9 |
| 6.846e-06 | -11.89 | CAMP_UP.V1_DN | MSigDB lists | CAMP_UP.V1_DN | 182 | 33 | 15632 | 1249 |
Jarid2,Plek,Eno2,Birc3,Map4k4,Nfkb1,Tuba4a,Gem,Fosb,Akt3,Zfp36,Ube2e2,Casp7,Ms4a6d,Serpinb2,Rgs1,Gng12,Snn,Ezr,Phldb1,Ets2,Dnaja1,Fut8,Peli1,Ubtd2,Prdm1,Palld,Stxbp1,Ccnd2,Il4ra,Cd83,Atp2b4,Me1 |
| 6.846e-06 | -11.89 | GSE6674_CPG_VS_PL2_3_STIM_BCELL_DN | MSigDB lists | GSE6674_CPG_VS_PL2_3_STIM_BCELL_DN | 182 | 33 | 15632 | 1249 |
Pim3,Ahr,Myo10,Spred1,Csrnp1,P2ry14,Tab2,Etv3,Myc,Gadd45g,Dock10,Ifrd1,Errfi1,Mrpl52,Osbpl3,Nfil3,Abcc1,Smc5,Fndc3a,Larp1,Ier3,Pik3cd,Mthfd2,Slc7a5,Hk2,AA467197,Rasgrp1,Vasp,Gch1,Dcun1d3,Dusp6,Gem,Asns |
| 6.846e-06 | -11.89 | GSE3982_MAC_VS_BCELL_UP | MSigDB lists | GSE3982_MAC_VS_BCELL_UP | 182 | 33 | 15632 | 1249 |
Dtx2,Hp,Gpd2,Cxcl10,Nr4a3,Ak4,Rcan1,Gcnt2,Gfpt1,Acp2,Cdkn1a,Trem1,S100a8,Cd86,Fzd5,Procr,Sap30,Ppp2r3a,Inhba,Nlrp3,Plau,Cd83,Myd88,Myo10,Flt1,Spsb1,P4ha2,Bcl6,Oas3,Cyfip1,Dennd1b,Tnfsf8,Scarf1 |
| 6.871e-06 | -11.89 | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN | MSigDB lists | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN | 158 | 30 | 15632 | 1249 |
Etv3,Tle3,Ahr,Nod1,P2ry12,Hivep2,Plac8,Tnf,Morc3,Ccng2,Dock10,Egr2,Parp11,Tmod3,Dck,St3gal1,Cd82,Ust,Hcls1,Plekha2,Klf2,Nfkb1,Ccnj,Birc3,Cd69,Vasp,Rasgrp1,Stx6,Med13,Nmi |
| 6.871e-06 | -11.89 | WU_CELL_MIGRATION | MSigDB lists | WU_CELL_MIGRATION | 158 | 30 | 15632 | 1249 |
Olr1,Pdgfc,Gng11,Col4a2,Il1a,Plagl1,Col18a1,Vcan,Rbpms,Mtus1,Dse,Axl,Plac8,Ptges,Dcbld2,Igf2bp2,Tnfaip2,Thbs1,Arid5b,Tgfbi,Ptgs2,Lpar1,Ptger4,Cd55,Jag1,Slpi,Serpine1,Lad1,Tuba4a,Gja1 |
| 6.871e-06 | -11.89 | GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN | MSigDB lists | GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN | 158 | 30 | 15632 | 1249 |
Rhoh,Cdkn2d,Atf3,Evl,Fas,Phip,Upp1,Slc25a25,Plekhf2,Gadd45b,P4ha2,Ntng2,Dusp2,Dennd1b,Rhoq,Mlkl,Cpd,Dusp5,Max,Fam111a,Tapbpl,Cdkn1a,Gfi1,Glrx,Armc8,Igsf8,Itgal,Btg2,Dgka,Mmd |
| 6.871e-06 | -11.89 | GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_DN | MSigDB lists | GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_DN | 158 | 30 | 15632 | 1249 |
Crlf3,Rras2,Rab3ip,Slfn5,Slc28a2,Ddx60,Aim2,Bcor,Gbp3,Sell,Tnfsf8,Egr2,Myc,Peli1,Lztfl1,Treml2,Dhx58,Eif2ak2,Ifit1bl1,Usp53,Dse,Ppp2r1b,Hmgcs1,Cd55,Filip1l,Stat1,Tlr1,Slc31a2,Ifit1bl2,Sesn3 |
| 6.915e-06 | -11.88 | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | 174 | 32 | 15632 | 1249 |
Stip1,Mob3c,Il1b,Abcc1,Cd82,Ust,Irak2,Rnf145,Osgin2,Ier3,Hmgcs1,C3,Ell2,Itga5,Ccrl2,Pla2g7,Med13,Ampd3,Myo1b,Zc3h12c,Nfkb1,Sdc4,Il1a,Kmo,Gsr,Tgs1,Znfx1,Tank,Tpst1,Dnaja1,Pik3r5,Txnrd1 |
| 6.915e-06 | -11.88 | GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_DN | MSigDB lists | GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_DN | 174 | 32 | 15632 | 1249 |
Arid5a,Cited2,Cenpe,Prdx5,Casp3,Irf4,Top3a,Rhoq,Atp11a,Mul1,Slco3a1,Prdm1,Daxx,Cd38,Plagl2,Rhoc,Slamf7,Zbp1,Itgal,Plk2,Lap3,Wars,Bcl9,Trib1,Pim1,Slc43a3,Sema4a,Fam53c,Dusp5,Ell2,Acp2,Actb |
| 6.920e-06 | -11.88 | IK1_01 | MSigDB lists | IK1_01 | 249 | 41 | 15632 | 1249 |
Parp8,Gadd45b,Phldb1,Abcc5,Itpr1,Cited2,Jun,Kcnj2,Tor1aip2,Il6,Psd,Ifnb1,Cxcl14,Abr,Prdm1,Nek6,Apba1,Icam1,Rnd1,Sav1,Atp2b4,Relb,Cd86,Ptch1,Spen,Zeb1,Rab10,Tnfsf15,Atxn7l1,Zscan29,Cd69,Kpna3,Il13ra1,Cox18,Nr4a3,Rbms1,Znrf1,Nfkb2,Tnip1,Mob3c,5430427O19Rik |
| 6.930e-06 | -11.88 | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | MSigDB lists | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | 770 | 96 | 15632 | 1249 |
Sass6,Tmtc2,Sgms2,Prnp,Egr1,Lrp8,Nfkbiz,Samhd1,Fbxo4,Plau,Fos,Slc7a11,Tmem200b,Cenpe,Nod2,Acsl1,Kif5c,Ell2,Endod1,Casp7,Ap3m2,Igf1r,Zc3h12c,Mcm9,Ccne1,Dcp1a,Sirt1,Trip13,Bcorl1,Slco3a1,St3gal6,Spata13,Mcm10,Cd164,Cd83,Crlf3,Tmc3,Gpsm2,Otud1,Plekhf2,Pim1,Cmpk2,Dcbld2,Dek,Rsbn1,Fubp1,Slc7a2,Gch1,Snx10,Nmi,Kat2b,Ubash3b,Cdkn2d,Bcor,Enpp4,Il15,Sgcb,Extl2,D16Ertd472e,Itgav,Ifrd1,Dnajb4,Uaca,Hmgcs1,Mtdh,Lrrc8c,Dusp16,Idi1,Rpgrip1l,Tor3a,Kctd12,Usp12,Upp1,Usp18,Prrg4,Prpf38a,Plagl2,Ccl3,Ddhd1,B3gnt5,Cers6,Hspa2,Ogfrl1,D1Ertd622e,Mcm6,Phf6,Trib3,Pcgf5,Pkp4,Pcdh7,Tor1aip1,Fzd1,Car13,Sh3bp4,Sap30,Tmeff1 |
| 7.050e-06 | -11.86 | import into cell | biological process | GO:0098657 | 469 | 58 | 20694 | 1406 |
Rab20,Slc9a1,Fcgr1,Fnbp1l,Adrb2,Abcc1,Scyl2,Fcgr2b,Xkr8,Ezr,Sh3bp4,Syk,Rhou,Snx2,Fcho2,Fchsd2,Ehd1,Actb,Cd14,Slc12a9,Itga4,Rac3,Msr1,Rhoq,Nlgn2,Rabgef1,Dennd1b,Lrp8,Carmil1,Calcrl,Jmjd6,Thbs1,Treml4,Grk3,Ldlr,4932438A13Rik,Ly75,Fpr2,Kcnj2,Snx10,Acsl1,Reps1,Lrp4,Slc7a2,Scarf1,Slc39a14,Trip10,Mapkapk2,Slc39a4,Lrp11,Htr2b,Marco,Dbnl,Slc31a1,Rin2,Clcn5,Cav1,Slc7a11 |
| 7.087e-06 | -11.86 | GO_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_SIGNALING_PATHWAY | 24 | 10 | 15632 | 1249 |
Casp8,Tab2,Ikbkg,Ripk2,Nfkbia,Tnfaip3,Nod2,Irak2,Nod1,Rnf34 |
| 7.087e-06 | -11.86 | GO_DETECTION_OF_OTHER_ORGANISM | MSigDB lists | GO_DETECTION_OF_OTHER_ORGANISM | 24 | 10 | 15632 | 1249 |
Nod1,Tlr1,Nod2,H2-Q7,H2-Q4,H2-Eb1,Tlr6,H2-Q6,Nlrc4,Tlr2 |
| 7.087e-06 | -11.86 | OSADA_ASCL1_TARGETS_DN | MSigDB lists | OSADA_ASCL1_TARGETS_DN | 24 | 10 | 15632 | 1249 |
Bcl2a1a,Crim1,Bcl2a1d,Birc3,Axl,Dusp1,Socs3,Bcl2a1b,Tgfbi,Sema3c |
| 7.100e-06 | -11.86 | SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | MSigDB lists | SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | 284 | 45 | 15632 | 1249 |
Mmp14,Pdpn,Edn1,Pla2g4a,Sod2,Ifi207,Slc16a1,Col4a2,Ifi214,Ifi203,Smpdl3b,Slpi,Ifi211,Fabp7,Lmo4,Plod2,Mndal,Marco,S100a8,Psat1,Fscn1,Dnajb4,Ifi204,Cp,Phgdh,Gpsm2,Ifi205,Eno1,Ifi209,Slc16a3,Ifi213,Slc25a37,Klf6,Wars,Slc7a5,Ifi208,Col11a2,Stip1,Igf2bp2,Serpinb2,Clic4,Prkx,Slc43a3,Ptgs2,Uchl1 |
| 7.150e-06 | -11.85 | alpha-beta T cell activation | biological process | GO:0046631 | 74 | 17 | 20694 | 1406 |
Stat3,Batf,Irf1,Irf4,Spn,Gadd45g,Tnfsf8,Tnfsf4,Il12b,Sema4a,Ptger4,Syk,Il6,Il15,Gpr18,Rsad2,Relb |
| 7.206e-06 | -11.84 | DAZARD_UV_RESPONSE_CLUSTER_G6 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G6 | 135 | 27 | 15632 | 1249 |
Zhx2,Vegfc,Stard7,Chd9,Fndc3a,Smc5,Ptk2,Rrs1,Casp8,Flrt2,Nfkb1,Cdyl,Jarid2,Klf7,Pikfyve,Phip,Cebpd,Phlpp1,Rin2,Tlk2,Mecp2,Cnot4,Bbx,Nr3c1,Birc2,Dock4,Mtus1 |
| 7.287e-06 | -11.83 | GO_POSITIVE_REGULATION_OF_INTERFERON_BETA_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERFERON_BETA_PRODUCTION | 29 | 11 | 15632 | 1249 |
Zc3hav1,Ifih1,Rnf135,Irf7,Tlr2,Irf1,Ddx58,Ifnar1,Ripk2,Tlr9,Tlr3 |
| 7.287e-06 | -11.83 | GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION | 29 | 11 | 15632 | 1249 |
Cd80,H2-Q7,Tnfsf4,Ebi3,Cd55,Ripk2,Il12b,Il18,H2-Q4,Syk,H2-Q6 |
| 7.317e-06 | -11.83 | MODULE_88 | MSigDB lists | MODULE_88 | 771 | 96 | 15632 | 1249 |
Lcn2,P4ha1,Casp2,Acsl1,Ier3,Zyx,Fos,Slc7a11,Ccl12,Ifit1bl1,Flt1,Nqo1,Stard5,Il4ra,Etv3,Pttg1,Ccnd2,Egr1,Tnfrsf14,Plau,Pfkfb3,Gch1,Slc7a8,Ifit1bl2,Junb,Hap1,Stoml1,Phlda1,Ube2l6,Tgfbi,Ak4,Smox,H2-Ab1,Glrx,Gng12,Tnfsf10,Il1rn,Cst7,Ccnd1,Isg15,Lif,Mthfr,Nfkbil1,Crim1,Cav1,Tnfrsf1b,Ikbkg,S100a8,Nfkbib,Alas1,Ppp4r2,Slpi,Trib1,Itga5,Rac3,Pim2,Nfil3,Dnajb2,Cdkn1a,Ldlr,Adam19,Ets2,Cited2,Nr4a1,Gadd45g,Dtnb,Psd,Ctsc,Arl4a,Cdk5r1,Aldh1b1,Fpr2,Sdc1,Col18a1,Dnase1l3,F10,Serpine1,Gdf15,Psd4,Dusp6,Ccr1,Ddit4,Il2rg,Phyh,Hmox1,Hp,Plat,Csf3r,Hspa2,Sele,Cp,Rnd1,Atp11a,Nupr1,Plk3,Cd14 |
| 7.679e-06 | -11.78 | B cell mediated immunity | biological process | GO:0019724 | 82 | 18 | 20694 | 1406 |
Pou2f2,Fcgr1,Fgl2,Myd88,Batf,Icosl,H2-Ab1,Swap70,C3,Cd55,Cd74,C1ra,Fcgr2b,Il4ra,Nod2,Irf7,Fas,C1rl |
| 7.724e-06 | -11.77 | GSE7852_LN_VS_THYMUS_TREG_UP | MSigDB lists | GSE7852_LN_VS_THYMUS_TREG_UP | 183 | 33 | 15632 | 1249 |
Abcc4,Ptger4,Ptprj,Parp3,Kif5c,Cxcl2,H2-Aa,Flnb,Phlpp2,Hopx,Cd86,Atp6v1d,Casp4,Ifit1bl2,Hvcn1,Gbp2,Slc28a2,Irak3,Rbm43,Ubash3b,Gbp3,Bcor,Gpr68,Irf4,Abcb1a,Prkce,Crbn,Nlrc5,Tnf,Ifit1bl1,Spn,Casp1,Cst7 |
| 7.724e-06 | -11.77 | GSE3982_MAC_VS_TH2_UP | MSigDB lists | GSE3982_MAC_VS_TH2_UP | 183 | 33 | 15632 | 1249 |
Plekhf2,Swap70,Egr2,Rab9,Spry2,Sertad3,Cd74,Ccl22,Enpp4,Etv5,Atm,P2ry2,Fzd5,Ifit3,Stxbp3,Hk2,Mmd,Inhba,Usp12,Ccrl2,Uchl1,Traf3ip2,C3,Hp,Ptk2,Azi2,Frmd4a,Ifit3b,Gcnt2,Clcn7,Acp2,Cdkn1a,Trem1 |
| 7.724e-06 | -11.77 | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | 183 | 33 | 15632 | 1249 |
Spred1,Olr1,Cd14,Gpc1,Prnp,Plagl1,Il1a,Ccl22,Nfkbiz,Ifrd1,Errfi1,Stk40,Acpp,Rbbp8,Flt1,Slc7a11,Trem1,Tfec,Cdkn1a,Il1rn,Slfn3,Trib1,Cpeb4,Hmox1,Socs3,Met,Hk2,Srxn1,Nrp2,Slfn4,Rrs1,Ccr1,Csrp1 |
| 7.724e-06 | -11.77 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | 183 | 33 | 15632 | 1249 |
Atp13a1,Tapbp,Cnot4,Ncoa5,Tnfsf8,Myc,Jun,Fos,Parp8,Dusp1,Klf6,Tnfaip3,Notch1,Traf1,Sell,Gbe1,Il4ra,Ccnd2,Mcoln2,Egr1,Tlr6,Evl,Ier2,Kctd12,Zfp36,Fosb,Dusp6,Dnajb2,Znrf1,Adrb2,Pim1,Socs3,Larp1 |
| 7.724e-06 | -11.77 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_UP | 183 | 33 | 15632 | 1249 |
Gna15,Cd86,Plk2,Heatr6,H2-Aa,Snx2,Pla2g7,Mmd,Tmem176a,Ebi3,H2-Ab1,Il13ra1,Trib1,Rab20,Fscn1,Tnfaip2,Nfil3,Rab32,Tcf4,Cd302,Irgq,Ccl2,Gpr35,Igsf6,Mafk,Nfkbie,Hlx,Marcksl1,Tmem176b,Pilra,Cd83,Pdgfc,Hck |
| 7.724e-06 | -11.77 | GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_DN | 183 | 33 | 15632 | 1249 |
Phlpp1,Glipr2,Arhgap26,Parp9,Dhx58,Tapbp,Irgm2,Dbnl,Clcn5,Stat2,Usp18,Rab19,Fpr2,Ddx58,Gbp3,Prdm1,Oas1a,Uba7,Psme2,Tnfsf14,Mov10,Clic5,Il15ra,Hsd17b7,Sec24a,Ust,Spata5l1,Map3k8,Ifi35,Etnk1,Dennd2a,Oas1g,Ldha |
| 7.724e-06 | -11.77 | GSE14308_TH1_VS_TH17_UP | MSigDB lists | GSE14308_TH1_VS_TH17_UP | 183 | 33 | 15632 | 1249 |
Dusp1,Eno1,Ttc39c,Cyfip1,Phgdh,Slfn8,Spry2,Gsr,Mlkl,Psme1,Socs1,Il4ra,Pde3b,Nfkb1,Hsd17b12,Cenpj,Rrs1,Zfp36,Slpi,Csf1,Ube2l6,Icosl,Trim21,Trim14,Kctd12,Wars,Stat1,Dgkh,Larp1,Slfn9,Acsl5,Pkp4,Mob3c |
| 7.724e-06 | -11.77 | GSE24292_WT_VS_PPARG_KO_MACROPHAGE_DN | MSigDB lists | GSE24292_WT_VS_PPARG_KO_MACROPHAGE_DN | 183 | 33 | 15632 | 1249 |
Vrk2,Tmem219,Herc6,Ifi35,Itga9,Trim14,Trim21,Isg20,Xaf1,Parp12,Ifit1bl2,Golga3,Ogfr,Fbxo4,Slamf7,Ahsa1,Pnpt1,Sla,Crlf3,Extl2,Daxx,Ifit1,Hhex,Zfp281,Calcrl,Parp14,Irgm2,Ogfrl1,Bcl2l11,Ifit2,Ifit1bl1,Axl,Swap70 |
| 7.724e-06 | -11.77 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_DN | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_DN | 183 | 33 | 15632 | 1249 |
Il4ra,Pttg1,Icam1,Palld,Mcmbp,Aff1,Fbrsl1,Jun,Slc2a1,Arid5a,Tagln,Dync1h1,Ccng2,Gadd45g,Ogfrl1,Dusp2,Sat1,Cxcl10,Phf6,Fam53c,Cpeb4,Mtmr14,Bambi,Fam102b,Whamm,Serpine1,Cenpj,Irf8,Maff,Hivep3,Usp12,Med13,Ext1 |
| 7.724e-06 | -11.77 | GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN | MSigDB lists | GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN | 183 | 33 | 15632 | 1249 |
Acpp,Itpr1,Cenpe,Bcl2l11,Vcan,Fgl2,Rsad2,Rhoq,Prnp,Sell,Socs1,P2ry14,Il4ra,Palld,Sla,Lcp2,Ccr1,Rgl1,Ppp2r3a,Rasgrp1,Spint2,Kctd12,Bcl9,Med13,Il18,Tlr3,Ripk2,Ell2,Ptgir,Trafd1,Nfil3,Il1rn,Prkx |
| 7.724e-06 | -11.77 | GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_DN | MSigDB lists | GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_DN | 183 | 33 | 15632 | 1249 |
Rapgef5,Gadd45b,Jun,Spic,Gpr35,Stap1,Stard5,Nfkbie,Nupr1,Slc30a4,Aim2,Arrdc4,Fpr2,Dcp2,Ahsa1,Ifit1,Ahrr,Jarid2,Junb,Rel,Slc7a5,Ext1,Hap1,Usp12,Rnf19b,Tlr3,Mtmr14,Acsl1,Col27a1,Gfpt1,Agpat4,Dusp16,Fmnl2 |
| 7.724e-06 | -11.77 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_DN | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_DN | 183 | 33 | 15632 | 1249 |
AA467197,Pla2g7,Jag1,Sema3c,Clic4,Gca,Il1b,Trem1,Stard7,Il13ra1,Ptafr,Asb13,Nsmaf,Clec5a,Top3a,Egr2,Tnfsf8,Triobp,Nqo1,Nod2,Parp8,Slc48a1,Batf,Ahr,Tnfaip3,Prrg4,Hlx,Mpp7,Agtrap,Sell,Prnp,F11r,Sgms2 |
| 7.771e-06 | -11.77 | GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 682 | 87 | 15632 | 1249 |
Edn1,Ikzf1,Myc,Ezr,Psmd10,Jun,Hinfp,Ciita,Atf3,Egr1,Lrp8,Etv3,Timeless,Sirt1,Ifi203,Dach1,Irf8,Ptch1,Dr1,Hcls1,Gfi1,Stat1,Ccnd1,Mdm2,Ifi213,Rbbp8,Ifi205,Eno1,Bmp2,Daxx,Notch1,Relb,Mxd1,Irf2,Hhex,Hif1a,Btg2,Ifi208,Txn1,Junb,Jarid2,Nfxl1,Zhx2,Cited2,Ets2,Ifi207,Rbl1,Nck1,Bcor,Nr1h3,Ifi214,Ifi211,Zeb1,Spen,Zfp36,Med13,Etv6,Jdp2,Ednrb,Ahrr,Nfkb1,Rel,Cav1,Mndal,Nfil3,Mtdh,Ifi204,Stat3,Mecp2,Hdac1,Aebp2,Tnf,Ifi209,Bcl6,Plk3,Prdm1,Zfp281,Sap30,Hopx,Ppp1r15a,Irf7,Fosb,Nfkb2,Il1b,Trib3,Nr4a3,Arid5b |
| 7.777e-06 | -11.76 | natural killer cell activation | biological process | GO:0030101 | 67 | 16 | 20694 | 1406 |
Ifna4,Stat5a,Ifnb1,Ifna5,Ifna2,Raet1e,Klrk1,Il12b,Stx11,Axl,H60b,Ifna1,Il18,Ikzf1,Ifna6,Prdx1 |
| 7.827e-06 | -11.76 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_UP | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_UP | 175 | 32 | 15632 | 1249 |
Cers6,Ift57,Phlpp1,Rffl,Aftph,Gpsm2,Tspan3,Casp1,Plekhf2,Dusp1,Ifit2,Hivep2,Cdc42ep2,Slc48a1,Sav1,Crlf3,Slc30a1,Plk3,Inpp5b,Asah2,Tuba4a,Psat1,Frmd6,Snn,Znrf1,Acsl1,Map2k4,Acvr1b,Parp11,Pim1,Ptgir,Dtx2 |
| 7.827e-06 | -11.76 | KRIEG_KDM3A_TARGETS_NOT_HYPOXIA | MSigDB lists | KRIEG_KDM3A_TARGETS_NOT_HYPOXIA | 175 | 32 | 15632 | 1249 |
Nupr1,Magohb,Psmb10,Upp1,Phf11a,Phf11c,Prpf38a,Ehd1,Phf11b,Cd40,Ptpn2,Ifi44,Dhx58,B3gnt5,Oas1g,Stat1,Ifi35,Ifit3b,Irf1,Phf11d,Gbp2b,Vcam1,Acsl5,Atm,Asns,Tnfsf14,Ifit3,Psme2,Oas1a,Stoml1,Stat4,Slc25a12 |
| 7.851e-06 | -11.75 | negative regulation of programmed necrotic cell death | biological process | GO:0062099 | 13 | 7 | 20694 | 1406 |
Rnf31,Birc2,Peli1,Cflar,Casp8,Birc3,Cav1 |
| 7.851e-06 | -11.75 | negative regulation of necroptotic process | biological process | GO:0060546 | 13 | 7 | 20694 | 1406 |
Cflar,Casp8,Rnf31,Birc3,Cav1,Birc2,Peli1 |
| 7.851e-06 | -11.75 | regulation of granulocyte macrophage colony-stimulating factor production | biological process | GO:0032645 | 13 | 7 | 20694 | 1406 |
Il18,Tlr9,Syk,Il1b,Il12b,Rasgrp1,Ddx58 |
| 7.852e-06 | -11.75 | Autoimmune thyroid disease | KEGG pathways | mmu05320 | 76 | 20 | 7931 | 713 |
Ifna2,H2-T22,Cd40,Ifna1,H2-Q4,H2-Q7,H2-Q6,Cd86,H2-M2,Ifna6,Il10,Cd80,H2-Aa,H2-T24,H2-Ab1,Ifna4,Fas,Ifna5,H2-Eb1,H2-T10 |
| 7.852e-06 | -11.75 | Autoimmune thyroid disease | KEGG pathways | ko05320 | 76 | 20 | 7931 | 713 |
Ifna2,H2-T22,H2-Q4,Ifna1,Cd40,H2-Q7,H2-M2,Ifna6,Cd86,H2-Q6,Cd80,Il10,H2-T24,H2-Aa,Ifna4,H2-Ab1,Ifna5,Fas,H2-Eb1,H2-T10 |
| 7.909e-06 | -11.75 | KEGG_ALLOGRAFT_REJECTION | MSigDB lists | KEGG_ALLOGRAFT_REJECTION | 40 | 13 | 15632 | 1249 |
H2-Aa,H2-Eb1,H2-Q4,Tnf,Cd86,Il10,H2-Q6,Cd40,Cd80,Fas,H2-Ab1,H2-Q7,Il12b |
| 7.909e-06 | -11.75 | AMIT_EGF_RESPONSE_60_HELA | MSigDB lists | AMIT_EGF_RESPONSE_60_HELA | 40 | 13 | 15632 | 1249 |
Ldlr,Tnfaip2,Nr4a3,Lif,Ccnd1,Plscr1,Fosb,Serpine1,Tiparp,Cited2,Sod2,Hsph1,Klf6 |
| 7.909e-06 | -11.75 | ONO_FOXP3_TARGETS_DN | MSigDB lists | ONO_FOXP3_TARGETS_DN | 40 | 13 | 15632 | 1249 |
Slfn4,Casp4,Casp1,Ccl5,Irf4,Tnfsf8,Sell,Sema4a,Il4ra,P2ry14,Cdkn1a,Rbl1,Slfn3 |
| 7.909e-06 | -11.75 | JIANG_TIP30_TARGETS_UP | MSigDB lists | JIANG_TIP30_TARGETS_UP | 40 | 13 | 15632 | 1249 |
Bcl6,Dusp1,Axl,P4ha1,Rapgef5,Vcan,Jag1,Pttg1,Calcrl,Arg2,Ier3,Malt1,Nfil3 |
| 7.909e-06 | -11.75 | PID_INTEGRIN3_PATHWAY | MSigDB lists | PID_INTEGRIN3_PATHWAY | 40 | 13 | 15632 | 1249 |
Itgav,Pdgfrb,Pdgfb,Tnc,F11r,Tgfbi,Sdc1,Sphk1,Plau,Sdc4,Kdr,Thbs1,Plaur |
| 7.970e-06 | -11.74 | negative regulation of hemopoiesis | biological process | GO:1903707 | 158 | 27 | 20694 | 1406 |
Tnfsf4,Irf1,Pf4,Nfkbia,Tmem176a,Pilrb1,Gpr68,Socs1,Stat5a,Hlx,Tmem178,Ubash3b,Notch1,Clec2d,Cd74,Fgl2,Zfp36,Zc3h12a,Ptpn2,Bcl6,Myc,Il4ra,Ifnb1,Nfkbid,Tmem176b,Trib1,Lyn |
| 8.143e-06 | -11.72 | HOLLMANN_APOPTOSIS_VIA_CD40_DN | MSigDB lists | HOLLMANN_APOPTOSIS_VIA_CD40_DN | 225 | 38 | 15632 | 1249 |
Ly75,Slc39a4,Ctsc,1110038F14Rik,Cers6,Ift57,Ap3b1,Slc16a3,Casp1,Sp140,Gsdmd,Dpy19l1,Armcx6,Tcf4,Psmb9,Homer1,Tspo,Sav1,Myd88,Zc3hav1,Psme1,Ifih1,Rtp4,Trim13,St3gal5,Ube2l6,Parp12,Tdrd7,Spint2,Pde4b,Psmb8,Casp4,Tap2,Tor1aip1,Notch2,Stat1,Casp7,Phyh |
| 8.162e-06 | -11.72 | regulation of myeloid leukocyte mediated immunity | biological process | GO:0002886 | 60 | 15 | 20694 | 1406 |
Syk,Fgr,Ptafr,Stxbp1,Cxcl1,Il4ra,Abr,Lyn,Hmox1,Rabgef1,Ddx58,Dnase1l3,Fcgr1,C3,Adora2b |
| 8.162e-06 | -11.72 | skeletal muscle cell differentiation | biological process | GO:0035914 | 60 | 15 | 20694 | 1406 |
Cited2,Egr2,Bcl9,Sap30,Fos,Egr1,Maff,Nupr1,Plagl1,Myc,Btg2,Atf3,Nr4a1,Hivep3,Notch1 |
| 8.244e-06 | -11.71 | CASc | smart domains | SM00115 | 11 | 7 | 9567 | 823 |
Casp1,Casp4,Cflar,Casp8,Casp3,Casp2,Casp7 |
| 8.255e-06 | -11.70 | GSE20715_0H_VS_24H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_24H_OZONE_LUNG_DN | 200 | 35 | 15632 | 1249 |
Pgs1,Sphk1,Ube2f,Notch1,Rab3ip,Sod2,Map3k6,Slc2a1,Cd302,Timp1,Cp,Pnp2,Rab21,Cxcl14,C3,Hp,Cdc42ep4,Trib1,Slc43a3,Adora2b,Plat,Cflar,Gsta3,Dusp16,Esd,Dusp6,Gdf15,Nampt,Pde4b,Lcn2,Pdlim7,Slpi,Alas1,Sap30,Maff |
| 8.318e-06 | -11.70 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_12H_DN | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_12H_DN | 136 | 27 | 15632 | 1249 |
Pttg1,H2-Q7,Pim3,Psmb9,H2-Q6,Znfx1,Lrp4,Rnf114,H2-Q4,Tnf,Nlrc5,Gsdmd,Dync1h1,Il18bp,Rnf24,Dusp8,Stat1,Arl5c,Trafd1,Keap1,Plat,Psmb8,Il12rb1,Wars,Trim56,Psme2,Ext1 |
| 8.346e-06 | -11.69 | regulation of vesicle-mediated transport | biological process | GO:0060627 | 582 | 68 | 20694 | 1406 |
Sdc1,Tlr2,Hmox1,Prkce,Cdk5r1,Lyn,Cav1,Il4ra,Rims3,Itgav,Sphk1,Il1b,Notch1,Il15ra,Lgals9,Sele,Axl,Apba1,Rnf139,Cd300lf,Cnn2,Il2rg,Abr,Ptafr,Cyfip1,Ptprj,Map2k1,Hap1,Adora2b,Fpr2,Src,Rab9,Hck,Rabgef1,Rab10,Il15,Serpine1,Nod2,Stap1,Stxbp3,Nlgn2,Fgr,Nr1h3,C3,Ptk2,Cd14,Sec24b,Htr2a,Tnf,Adora2a,P2ry2,Cacna1d,Ehd1,Stxbp1,Syk,Pla2g4a,Glrx,Fcgr2b,Sdc4,Scyl2,Siglece,Ezr,Rab21,Rab20,Angpt1,Ccl2,Fcgr1,Adrb2 |
| 8.403e-06 | -11.69 | Ifngr1 (interferon gamma receptor 1) | protein interactions | 15979 | 5 | 5 | 7778 | 753 |
Socs1,Jak2,Ptpn2,Stat1,Rnf19b |
| 8.430e-06 | -11.68 | PID_PTP1B_PATHWAY | MSigDB lists | PID_PTP1B_PATHWAY | 52 | 15 | 15632 | 1249 |
Pdgfrb,Cav1,Txn1,Src,Stat5a,Tyk2,Spry2,Csf1,Pdgfb,Stat3,Fgr,Lyn,Socs3,Hck,Jak2 |
| 8.430e-06 | -11.68 | GO_NEGATIVE_REGULATION_OF_DNA_BINDING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DNA_BINDING | 52 | 15 | 15632 | 1249 |
Jun,Ifi205,Ifi209,Mndal,Ifi213,Nfkbia,Ifi203,Ifi208,Ifi211,Ifi214,Ifi204,Hmox1,Lhx2,Ifi207,Jak2 |
| 8.445e-06 | -11.68 | KRIEG_HYPOXIA_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_VIA_KDM3A | 46 | 14 | 15632 | 1249 |
Serpine1,Ppp1r15a,Vezt,Gdf15,Birc3,Junb,AA467197,Nfkbie,Nrp2,Edn1,Hmox1,Zc3h12a,Plaur,Clec4e |
| 8.445e-06 | -11.68 | GO_POSITIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | 46 | 14 | 15632 | 1249 |
Tlr3,Tlr9,Ripk2,Hmox1,Hif1a,Adora2b,Cd74,Tlr2,Il4ra,Il1b,Eif2ak2,Tnf,P2ry2,Il6 |
| 8.486e-06 | -11.68 | MAPK signaling pathway | WikiPathways | WP493 | 159 | 37 | 4813 | 540 |
Dusp6,Casp7,Casp8,Daxx,Nfkb1,Fos,Akt3,Il1a,Hspa1a,Pdgfb,Casp2,Casp1,Myc,Dusp5,Map4k4,Fas,Nr4a1,Map2k4,Map2k1,Acvr1b,Map3k6,Tnf,Rasgrp1,Mapkapk2,Crkl,Tab2,Pdgfrb,Traf2,Dusp4,Jun,Casp3,Ikbkg,Cd14,Il1b,Map3k8,Dusp1,Max |
| 8.503e-06 | -11.68 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_UP | 192 | 34 | 15632 | 1249 |
Dnaja1,Rnf114,Tnf,Mid1,Ifrd1,Ppp2r5a,Pde1b,Fut8,Tbc1d1,Pla2g4a,Agtrap,Il1a,Pml,Ier2,Hck,Rbl1,Clec4e,Tal2,Gys1,Lgals9,Gdf15,Uba7,Vasp,Cxcl2,Hivep3,Sap30,Cdc42ep4,Adrb2,Usp42,Kcna3,Ptprj,Abcc1,Tnip1,Cxcl1 |
| 8.503e-06 | -11.68 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | 192 | 34 | 15632 | 1249 |
Plau,Spred1,Angpt1,Prdm1,Lif,Zfp281,Dmxl2,Nr3c1,Tmem171,Bnip3,Mmp14,Dennd1b,Il6,Itgb8,Vcan,Ccl12,Ass1,Hmga1,Clcf1,Adam19,Dcbld2,Filip1l,Ell2,Ak4,Phlda1,Vasn,Eya4,Ppp2r3a,Maff,Slc4a7,Pid1,Sema3c,Plod2,Serpine1 |
| 8.527e-06 | -11.67 | MARTINEZ_RB1_TARGETS_DN | MSigDB lists | MARTINEZ_RB1_TARGETS_DN | 479 | 66 | 15632 | 1249 |
Pdgfc,Notch1,Myo10,Ube2f,Upp1,Atp11a,Itga4,Marcksl1,Magohb,Kdm5b,Rsad2,Egr2,Rbbp8,Sp110,Bambi,Tgfbi,Nsmaf,Parp3,Slc7a5,Lad1,Fubp1,Tuba4a,Tle3,Ahr,Me1,Prdx1,Pilra,Pfkfb3,Clec4e,Gclc,Prnp,Pttg1,Arrdc4,Atf3,Col18a1,Ncoa5,Cnot4,Cxcl14,Prokr1,Fcgr2b,Slc44a1,Prkce,Msr1,Fos,Tspan3,Mrpl52,Morc3,Itgav,Esd,Fam162a,Pmepa1,Cdkn1a,Idi1,Ms4a6d,Trib1,Acsl1,Hmgcs1,Max,Slc39a14,Rhou,Egln3,Plod2,Hdc,S100a8,Ltbp2,Rnf14 |
| 8.625e-06 | -11.66 | GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 144 | 28 | 15632 | 1249 |
Prrg4,Mxd1,Plk3,Relb,Clec4e,Arid5a,Bcl2l11,Ezr,Klf6,Mafk,S1pr2,Stap1,Ier3,Mafg,Trib1,Zc3h12a,Dnaja2,Ell2,Usp31,Rcl1,Bambi,Cxcl1,Gch1,Csrp1,Adora2a,Slamf9,Nfkbib,Phlda1 |
| 8.625e-06 | -11.66 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_UP | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_UP | 144 | 28 | 15632 | 1249 |
Nr4a1,Dusp1,Serp1,Swap70,Mapkapk2,Cdk5r1,Kdm4a,Adar,Pfkfb3,Nod1,Cd38,Notch1,Rgs3,Dusp6,Map4k4,Jarid2,Plscr1,Bcl9,Reps1,Kctd12,Hivep3,Cd200,Atp10a,Pik3cd,Itga9,Orai2,Znrf1,Gfi1 |
| 8.704e-06 | -11.65 | GSE23695_CD57_POS_VS_NEG_NK_CELL_DN | MSigDB lists | GSE23695_CD57_POS_VS_NEG_NK_CELL_DN | 184 | 33 | 15632 | 1249 |
Cited2,Hspa1a,Trip10,Plac8,Ccng2,Ythdf1,Gadd45g,Cox17,Top3a,Arl4a,F11r,Cdkn2d,Plk3,Slc28a2,Gem,Ptch1,Casp4,Brd2,Nampt,Arid4a,Tmem176a,Maff,Rab20,Map3k8,Ttc39b,Ptgs2,Kdm6b,Fam53c,Fam20c,Plat,Tax1bp1,Clic4,Plcl2 |
| 8.704e-06 | -11.65 | GSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_DN | MSigDB lists | GSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_DN | 184 | 33 | 15632 | 1249 |
Klf2,Hk1,Slpi,Tlr1,Zfp36,Trim14,Ube2l6,Arid5b,Irf1,Ms4a6d,Kcna3,Cd200,Parp3,Tlr3,Rnf19b,Dusp28,Pmepa1,Jun,Arid5a,Acpp,Rsad2,Treml2,Ppp2r5a,Slco3a1,Ifih1,Arl4a,Zfp281,Ddx58,Cdkn2d,Tlr6,Samhd1,Gbp2,Hvcn1 |
| 8.704e-06 | -11.65 | GO_RESPONSE_TO_KETONE | MSigDB lists | GO_RESPONSE_TO_KETONE | 184 | 33 | 15632 | 1249 |
Cd38,Tspo,Socs1,Nr1h3,Sphk1,Fas,Errfi1,Ccnd1,Ifnb1,Edn1,Prkce,Il6,Fos,Dusp1,Src,Klf6,Ccl12,Ass1,Il1b,Cdkn1a,Thbs1,Adrb2,Ptafr,Ptger4,Tnfsf4,C3,Socs3,Klf2,Cav1,Fosb,Junb,Ccne1,Ccl5 |
| 8.704e-06 | -11.65 | GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | 184 | 33 | 15632 | 1249 |
Zmynd15,Klf6,Ifit1bl1,Dpy19l1,Rab32,Parp8,Agrn,Ogfrl1,Aftph,Spata13,Rnf135,Cdkn2d,Plau,Kif9,Cd86,Samsn1,Fosb,Cenpj,Pik3r6,Gbp7,Ifit1bl2,Pde7b,Vasp,Kctd12,Trim21,Kif3c,Cxcl10,Mtmr14,Dyrk2,Keap1,Fam102b,Thbs1,Cd82 |
| 8.704e-06 | -11.65 | GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_DN | 184 | 33 | 15632 | 1249 |
Tnf,Ifit2,Ccl12,Arhgef3,Sat1,Rab21,Edn1,Ccl2,Batf2,Fgl2,Il1a,Icam1,Atp11a,P2ry14,Nxf1,Slc25a25,Plau,Rgs3,Ppp1r15a,Lcp2,Cd274,Maff,Kctd12,Oasl1,Mmp9,Traf3ip2,Usp42,Il18,Ccl4,Asf1a,Serpinb2,Tnfaip2,Ap3m2 |
| 8.704e-06 | -11.65 | GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_DN | MSigDB lists | GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_DN | 184 | 33 | 15632 | 1249 |
Il6,Ifi205,Ifi209,Psmd10,Ifi213,Ifi207,Ahsa1,Prdx1,Sell,Ifih1,Isg15,Ifi214,Icam1,Col18a1,Ube2e1,Nck1,Ifi203,Plscr1,Ifi208,Ifi211,Rrs1,Lcn2,Mndal,Dach1,Junb,Psmb8,H3f3b,Asf1a,Cxcl1,Map2k4,Ifi204,Pim2,Ell2 |
| 8.704e-06 | -11.65 | GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP | MSigDB lists | GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP | 184 | 33 | 15632 | 1249 |
Ccl4,Gfi1,Filip1l,Dusp5,Egr3,Phf6,Zfp36,Arl5b,Zeb1,Leng9,Cd69,Maff,Nfkbid,Csf3,Dusp6,Tnfrsf1b,Junb,Cd274,Ncoa7,Egr1,Malt1,Nfkbiz,Plk3,Ier2,Gmppb,Trim13,Dusp2,Egr2,Ifnb1,C1ra,Agrn,Nr4a1,D16Ertd472e |
| 8.822e-06 | -11.64 | GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 152 | 29 | 15632 | 1249 |
Notch2,Prkar2b,Plaur,Mmp9,Spire1,Itga9,Rnf145,Isg20,Rasgrp1,Psd4,Klf2,Lcp2,Cnp,Rbm43,Slc28a2,Samhd1,Rhoh,Hhex,P2ry14,Ddx58,Cyth3,Ccr3,Fgl2,Dhrs9,Hivep2,Slc25a37,Csf3r,Bcl6,Nlrc4 |
| 8.822e-06 | -11.64 | GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | 152 | 29 | 15632 | 1249 |
Papss2,Tpi1,Atf3,Samhd1,Gbp2,Lipg,Txnrd1,Insl6,Ifit2,Dhx58,I830077J02Rik,Dusp4,Il6,Egr2,Ctsc,Nr4a3,Cxcl10,Fmnl2,Serpinb2,Polr2g,Fam102b,Notch2,Plod2,Higd1a,Gch1,Slc31a2,Plek,Fzd1,Stx11 |
| 8.848e-06 | -11.64 | GSE22886_TH1_VS_TH2_48H_ACT_DN | MSigDB lists | GSE22886_TH1_VS_TH2_48H_ACT_DN | 176 | 32 | 15632 | 1249 |
Plcl2,Jak2,Rsbn1,Cldnd1,Prkx,Parp11,Max,Ptger4,Filip1l,Egln3,Parp12,Isg20,Ampd3,Lnpep,Aff1,Cd164,Bfar,Crlf3,Herc3,Adar,Phip,Prnp,Arg2,Trim12c,Il4ra,Arhgap26,Rsad2,Pla2g4a,Rgs14,Psmb9,Mgat1,Rhof |
| 8.870e-06 | -11.63 | GO_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 92 | 21 | 15632 | 1249 |
Sema4a,Il12b,Clec4d,Cd180,Icam1,Ptger4,Ifna2,Relb,Clec4e,Ifna1,Notch2,Batf,Plcl2,Cd86,Itgal,Swap70,Ifna5,Ifnb1,Il6,Ifna6,Irf4 |
| 8.918e-06 | -11.63 | GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_UP | 160 | 30 | 15632 | 1249 |
Plagl1,Kdm4a,Upp1,Gbe1,Lif,Aff1,Tnfaip3,Rbbp8,Ankrd17,Tcf4,Plac8,Hsph1,Plekhf2,Agrn,Cers6,Ggct,Dnajb4,Frmd4a,Psmb6,Rnaset2b,Htr2b,Rnaset2a,Daam1,Plod2,P4ha1,Mmd,Eef1e1,Sap30,Plscr1,H2-Aa |
| 8.918e-06 | -11.63 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_UP | 160 | 30 | 15632 | 1249 |
Tnfsf8,Hdac1,Bcl2l11,Parp8,Klf3,Spsb1,Dock4,Arid5a,Spred1,Fas,Psmb10,Etv3,Cyth3,Ext1,Cnn3,Wdr59,Dgka,Card6,Sesn3,Pde4b,Abtb2,Sipa1l1,Cacybp,Lad1,Tnip1,Stat1,Ifi35,Pik3cd,Rcn1,Parp11 |
| 8.918e-06 | -11.63 | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | MSigDB lists | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | 160 | 30 | 15632 | 1249 |
Gch1,Eno2,Irf7,Atp6v1d,Parp12,Rapgef2,Pik3cd,Odc1,Hcls1,Arf4,Socs7,Cdkn1a,Pmepa1,Dnajb2,Apobec3,Ehd1,Jun,Itpr1,Timp1,Egr2,Stat3,Hspa2,Optn,Cdkn2d,Plk3,Atf3,Sphk1,Upp1,F11r,Dusp14 |
| 8.918e-06 | -11.63 | GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN | MSigDB lists | GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN | 160 | 30 | 15632 | 1249 |
Igsf6,Treml2,Mafk,Pik3r5,Znfx1,Tspo,Lpcat2,Stau1,Klf7,Ahr,Prdm1,Mxd1,Tmem176b,Rnf139,Trim13,Znrf3,Trim26,Ext1,Ampd3,Usp12,Birc3,Ccl5,Gch1,Irf7,Tax1bp1,Tmem123,Adam19,Dusp5,Pik3cd,Lyn |
| 8.923e-06 | -11.63 | GSE36095_WT_VS_HDAC9_KO_TREG_UP | MSigDB lists | GSE36095_WT_VS_HDAC9_KO_TREG_UP | 168 | 31 | 15632 | 1249 |
Cdkn1a,Pfkl,H3f3b,Ldha,Ell2,Mtmr14,Slc43a3,Pim1,Phlda1,Ppp2r3a,Mmd,Nfkb1,Dusp6,Map2k1,Casp8,Plk2,Samsn1,Ppfibp1,Tnfaip3,Lif,Nfkbiz,Usp18,Spata13,Hif1a,Pde1b,Cish,Hdac1,Rapgef5,Nfkbia,Cyfip1,Arhgef3 |
| 8.962e-06 | -11.62 | regulation of neurogenesis | biological process | GO:0050767 | 954 | 100 | 20694 | 1406 |
Ednrb,Bcl6,Agrn,Mark2,Mosmo,Mycl,Nlgn2,Igf1r,Ccl5,Zhx2,Kat2b,Met,Nck1,Katna1,Etv5,Kdr,Cx3cl1,Zswim4,Tnf,P2ry2,P2ry12,Tcf4,Fzd1,Sirt1,Mdm2,Il1b,Hmga2,Il15ra,Fubp1,Itpr1,Dbnl,Pbx1,Clcf1,Cdk5r1,Lyn,Cav1,Kremen1,Cd38,Plk2,Rapgef2,Lhx2,Bmp2,Sema4a,Hif1a,Casz1,Il6,Cyfip1,Kdm4a,Jag1,Mmd,Cflar,Myc,Prag1,Rac3,Zeb1,Dync1i2,Ptk2,Stap1,Sipa1l1,Sema4c,Spen,D16Ertd472e,Ifrd1,Csf1,Lrp8,Fas,Flrt2,Hdac1,Ust,Sdc2,Cx3cr1,Rab21,Kif3c,Mecp2,Vegfc,Mov10,Tspo,Ehd1,Tnfrsf1b,Scarf1,Notch1,Rgs14,Gfi1,Rap1gap2,Sphk1,Crkl,Tlr2,Stat3,Sema3c,Map4k4,Nr3c1,Eif4g2,Ldlr,Map2k1,Hap1,Scn1b,Lif,Lrp4,Lpar1,Mul1 |
| 9.119e-06 | -11.61 | regulation of myeloid cell apoptotic process | biological process | GO:0033032 | 34 | 11 | 20694 | 1406 |
Hcar2,Ccl5,Nod2,Slc7a11,Stat5a,Kitl,Fcgr2b,Il18,Sirt1,Clec5a,Pik3cd |
| 9.119e-06 | -11.61 | negative regulation of B cell activation | biological process | GO:0050869 | 34 | 11 | 20694 | 1406 |
Atm,Bcl6,Prdm1,Samsn1,Casp3,Lyn,Parp3,Tnfaip3,Il10,Fas,Fcgr2b |
| 9.119e-06 | -11.61 | positive regulation of interleukin-10 production | biological process | GO:0032733 | 34 | 11 | 20694 | 1406 |
Lgals9,Tnfsf4,Cd274,Cd83,Il12b,Tlr9,Cd34,Irf4,Nod2,Tlr2,Ptger4 |
| 9.139e-06 | -11.60 | Small cell lung cancer | KEGG pathways | ko05222 | 83 | 21 | 7931 | 713 |
Col4a2,Ptk2,Akt3,Itgav,Nos2,Max,Cycs,Apaf1,Nfkb1,Birc3,Ptgs2,Birc2,Traf1,Ccnd1,Nfkbia,Ccne1,Ikbkg,Myc,Pik3cd,Traf5,Traf2 |
| 9.139e-06 | -11.60 | Small cell lung cancer | KEGG pathways | mmu05222 | 83 | 21 | 7931 | 713 |
Birc3,Apaf1,Nfkb1,Max,Cycs,Akt3,Col4a2,Ptk2,Nos2,Itgav,Traf5,Traf2,Myc,Pik3cd,Birc2,Ccnd1,Traf1,Ccne1,Nfkbia,Ikbkg,Ptgs2 |
| 9.235e-06 | -11.59 | ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN | MSigDB lists | ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN | 65 | 17 | 15632 | 1249 |
Angpt1,Etv5,Tax1bp1,Cxcl1,Mafg,Ier3,Dnajb4,Pim1,Slc43a3,Egr1,Atf3,Nqo1,Ddit4,Jun,Hspa1a,Txnrd1,Klf6 |
| 9.246e-06 | -11.59 | AP-1 | interpro domains | IPR000837 | 9 | 6 | 19984 | 1430 |
Batf,Batf2,Fos,Fosb,Jdp2,Atf3 |
| 9.246e-06 | -11.59 | Caspase_his_AS | interpro domains | IPR016129 | 9 | 6 | 19984 | 1430 |
Casp4,Casp8,Casp1,Casp7,Casp3,Casp2 |
| 9.305e-06 | -11.59 | intracellular organelle lumen | cellular component | GO:0070013 | 3799 | 320 | 20747 | 1409 |
Mcm6,Ifi213,Aebp2,Tor3a,Birc3,Psme1,Aldh1b1,Ets2,Sod2,Max,Dock10,Socs1,Trip10,Arl4a,Oas1a,Tnip1,Bcl6,Notch2,Smc5,Slc9a1,Cacybp,Hat1,Oas1g,Ahrr,Malt1,Ptk2,Htr2b,Polr2g,Mtdh,Dusp16,Nfkb1,Morc3,Zhx2,Golga3,Carmil1,Hivep2,Isg20,Anp32a,Dusp4,Prdm9,Rabgef1,Hinfp,Itpkc,Shfl,Olr1,Rel,Stx6,Phf11d,N4bp1,Hmox1,Arid4a,Hck,Adar,Prdx5,Timeless,Gpc1,Rgs14,Stat1,Phlpp1,Nfkbie,Nek6,Med21,Rnaset2b,Daxx,Lyn,Pim1,Stat5a,Mier3,Rars,Mdm2,Tent4a,Spen,Rilpl1,Riox2,Plagl1,Mcm10,Rbpms,Tdrd7,Stat3,Etv6,Ccnd1,Sertad3,Relb,Ccnd2,Ifi205,Rnaset2a,Rsad2,Ppm1k,Lnpk,Dock4,Slc44a1,Rbbp8,Psma6,Ago3,Tut7,Ep400,Kat2b,Smox,Dennd1b,Ezr,Edn1,Vezt,Hif1a,Ikbke,Mcmbp,Cdkn2d,Med13,Hspa1a,Oasl1,Cenpe,Hilpda,Glrx,Plekhg1,Trim21,Actb,Mrpl52,Mdfic,Parp10,Casp8,Psme2,Stxbp1,Tap2,Setdb2,Plscr1,Uchl1,Rpgrip1l,Spire1,Ell2,Gja1,Sqstm1,Mppe1,Serpinb9,Ifi208,Hmga2,Parp9,Gbp2,Lap3,H3f3b,Pfkfb3,Tcea1,Pnpt1,Ifi203,Oas3,Ccne1,Mxd1,Sinhcaf,Kdm4a,Ifi211,Pbx1,Tnks1bp1,Nmi,Tra2a,Arid5a,Tfec,Gsdmd,Irf7,Taf4b,Cited2,Fas,Klf3,Itpr1,Rai14,Eef1e1,Klf6,Brd2,Higd1a,Ifi207,Mapkapk2,Sp140,Ciapin1,Mndal,Aim2,Cebpd,Myc,Hspa1b,Rgs3,Cycs,Plk3,Crkl,Rnf34,Parp3,Sbds,Mecp2,Ppp4r2,Ifi209,Dnajb4,Nampt,Irf4,Cenpj,Samhd1,Pcgf5,Irf2,Fubp1,Psip1,Hdac1,Etv3,Nr1h3,Spata13,Gfi1,Atf3,Fosb,Alas1,Aff1,Cdkn1a,Ak4,Casz1,Cox17,Bbx,Asap3,Cutc,Sik3,Myo10,Nr3c1,Zfp281,Nfkbiz,Tulp3,Phf6,Ier2,Tpx2,Ubr4,Crbn,Zc3h12a,Jarid2,Prpf4,Oas1b,Acsl5,Pdk3,Asf1a,Egr2,Sap30,Jak2,Txnrd1,Irf8,Rgcc,Ciita,Phf11c,Maml2,Ifi204,Egr1,Abtb2,Bcorl1,Nxf1,Dtx3l,Dtx2,Hsph1,Top3a,Gch1,Vps54,Atm,Rrs1,Tma16,Prdx1,Mtus1,Hspa2,Mark2,Keap1,Stap1,Sh3bgrl2,Phf11b,Sp100,Ctsc,Ikzf1,Etv5,Phf11a,Plekha5,Snapc1,Upp1,Tcf4,Kdm6b,Dyrk2,Stk40,Jmjd6,Jun,Irf1,Ifi214,Rapgef5,Oasl2,Mdn1,Il15,Zeb1,Cyth3,Fam111a,Etnk1,Cdyl,Cx3cr1,Klf2,P4ha2,Clic4,Noc4l,Psmb6,Ccdc86,Bnip3,Junb,Mafk,Sirt1,Klf8,Syne2,Oas2,Agtrap,Kdm5b,Dr1,Pou2f2,Ptpn2,Fos,Dse,Pml,Tasor2,Batf,Rcl1,Trib3,Cnp,Wdr43,Dcp2,Rbl1,Tle3,Ptges,Mpp7,Cdk5r1,Phlda1,Clcn7 |
| 9.504e-06 | -11.56 | GO_PROTEIN_COMPLEX_BINDING | MSigDB lists | GO_PROTEIN_COMPLEX_BINDING | 847 | 103 | 15632 | 1249 |
Fas,Cx3cl1,Irs2,Kat2b,Kif9,Syk,Ptpn2,Mmp14,Katna1,Fcgr2b,Ifna5,Mid1,Ifnb1,S1pr2,Itga5,Mmp9,Max,Rcsd1,Lyn,Itga9,Whamm,Fscn1,Cdkn1a,Wdr43,Dnajb2,H3f3b,Atm,S100a8,Cep350,Casp8,Cnn3,Syne2,Tulp3,Cd74,Gnb4,Ifna2,H2-Q6,Traf2,Micall2,Hdac1,Vcam1,Ppp2r2a,Hsd17b12,Fcgr4,Mmp13,Snx2,Phip,Prnp,Htr2a,Fcgr1,Ciita,Ifna1,Sbds,Pik3r5,Bcl2l11,Rab32,Nfkbia,Cenpe,H2-Q4,Ezr,Cyfip1,Myc,Triobp,Kif5c,Adrb2,Acvr1b,Kdr,Hcls1,Cflar,Actb,Igf1r,Ccne1,Ptch1,Itgal,Gna15,Sirt1,Mthfr,Apba1,H2-Q7,Fgr,Icam1,Hif1a,Myo10,Ripk3,Src,Rgs14,Psmb9,Dbnl,Casp3,Mlkl,Acvrl1,Ccnd1,Acvr1,Lztfl1,Tapbpl,Kif3c,Tgfbi,Thbs1,Myo1b,Plk2,Ifna6,Antxr1,Pdgfb |
| 9.516e-06 | -11.56 | membrane-enclosed lumen | cellular component | GO:0031974 | 3800 | 320 | 20747 | 1409 |
Mier3,Rars,Mdm2,Tent4a,Spen,Plagl1,Mcm10,Riox2,Rilpl1,Rbpms,Tdrd7,Itpkc,Olr1,Shfl,Rel,Hmox1,Stx6,Phf11d,N4bp1,Arid4a,Adar,Hck,Prdx5,Stat1,Rgs14,Gpc1,Timeless,Phlpp1,Med21,Nek6,Nfkbie,Daxx,Lyn,Rnaset2b,Stat5a,Pim1,Ptk2,Malt1,Polr2g,Htr2b,Mtdh,Dusp16,Morc3,Zhx2,Nfkb1,Golga3,Carmil1,Hivep2,Anp32a,Isg20,Rabgef1,Prdm9,Dusp4,Hinfp,Aebp2,Mcm6,Ifi213,Tor3a,Birc3,Aldh1b1,Psme1,Ets2,Sod2,Dock10,Max,Socs1,Arl4a,Trip10,Oas1a,Tnip1,Bcl6,Smc5,Notch2,Slc9a1,Cacybp,Ahrr,Oas1g,Hat1,Gja1,Sqstm1,Serpinb9,Hmga2,Ifi208,Mppe1,Parp9,Gbp2,Lap3,Ifi203,Oas3,Pnpt1,Pfkfb3,Tcea1,H3f3b,Ccne1,Mxd1,Sinhcaf,Ifi211,Kdm4a,Pbx1,Trim21,Plekhg1,Glrx,Actb,Casp8,Parp10,Mdfic,Mrpl52,Psme2,Stxbp1,Tap2,Setdb2,Plscr1,Uchl1,Rpgrip1l,Ell2,Spire1,Smox,Dennd1b,Ezr,Edn1,Vezt,Hif1a,Ikbke,Mcmbp,Cdkn2d,Med13,Hspa1a,Oasl1,Hilpda,Cenpe,Stat3,Etv6,Ccnd1,Ccnd2,Relb,Sertad3,Rnaset2a,Ifi205,Rsad2,Dock4,Ppm1k,Lnpk,Slc44a1,Psma6,Rbbp8,Tut7,Ago3,Ep400,Kat2b,Casz1,Cox17,Asap3,Bbx,Cutc,Sik3,Zfp281,Myo10,Nr3c1,Nfkbiz,Phf6,Tulp3,Tpx2,Ier2,Zc3h12a,Ubr4,Crbn,Jarid2,Oas1b,Acsl5,Prpf4,Pdk3,Hdac1,Psip1,Etv3,Spata13,Nr1h3,Gfi1,Atf3,Fosb,Alas1,Cdkn1a,Aff1,Ak4,Rgs3,Hspa1b,Cycs,Plk3,Rnf34,Crkl,Parp3,Sbds,Ppp4r2,Mecp2,Nampt,Irf4,Dnajb4,Ifi209,Samhd1,Cenpj,Irf2,Pcgf5,Fubp1,Nmi,Tra2a,Arid5a,Tnks1bp1,Tfec,Irf7,Gsdmd,Klf3,Fas,Cited2,Taf4b,Rai14,Itpr1,Eef1e1,Mapkapk2,Higd1a,Ifi207,Brd2,Klf6,Ciapin1,Sp140,Mndal,Aim2,Cebpd,Myc,Agtrap,Oas2,Kdm5b,Ptpn2,Pou2f2,Dr1,Fos,Dse,Tasor2,Pml,Rcl1,Batf,Trib3,Cnp,Wdr43,Rbl1,Dcp2,Tle3,Mpp7,Ptges,Phlda1,Cdk5r1,Clcn7,Ifi214,Rapgef5,Irf1,Jun,Oasl2,Il15,Mdn1,Zeb1,Cyth3,Fam111a,Etnk1,Klf2,Cdyl,Cx3cr1,P4ha2,Clic4,Psmb6,Noc4l,Bnip3,Ccdc86,Junb,Mafk,Sirt1,Klf8,Syne2,Mark2,Keap1,Stap1,Phf11b,Sh3bgrl2,Sp100,Ctsc,Ikzf1,Etv5,Phf11a,Snapc1,Plekha5,Tcf4,Upp1,Kdm6b,Jmjd6,Stk40,Dyrk2,Asf1a,Sap30,Egr2,Jak2,Txnrd1,Rgcc,Irf8,Phf11c,Ciita,Abtb2,Maml2,Egr1,Ifi204,Bcorl1,Dtx3l,Nxf1,Dtx2,Hsph1,Vps54,Gch1,Top3a,Atm,Rrs1,Tma16,Mtus1,Prdx1,Hspa2 |
| 9.516e-06 | -11.56 | organelle lumen | cellular component | GO:0043233 | 3800 | 320 | 20747 | 1409 |
Etv6,Stat3,Ccnd1,Ccnd2,Relb,Sertad3,Rnaset2a,Ifi205,Rsad2,Slc44a1,Dock4,Lnpk,Ppm1k,Ago3,Tut7,Psma6,Rbbp8,Kat2b,Ep400,Smox,Dennd1b,Edn1,Ezr,Hif1a,Vezt,Mcmbp,Ikbke,Med13,Cdkn2d,Oasl1,Hspa1a,Hilpda,Cenpe,Plekhg1,Trim21,Glrx,Parp10,Casp8,Mrpl52,Mdfic,Actb,Stxbp1,Psme2,Tap2,Setdb2,Uchl1,Plscr1,Ell2,Spire1,Rpgrip1l,Gja1,Sqstm1,Parp9,Hmga2,Serpinb9,Ifi208,Mppe1,Ifi203,Oas3,H3f3b,Pfkfb3,Tcea1,Pnpt1,Lap3,Gbp2,Ccne1,Mxd1,Ifi211,Kdm4a,Sinhcaf,Pbx1,Tor3a,Aebp2,Mcm6,Ifi213,Aldh1b1,Psme1,Birc3,Dock10,Max,Sod2,Ets2,Socs1,Oas1a,Arl4a,Trip10,Bcl6,Tnip1,Slc9a1,Smc5,Notch2,Ahrr,Oas1g,Hat1,Cacybp,Htr2b,Polr2g,Ptk2,Malt1,Mtdh,Dusp16,Morc3,Zhx2,Nfkb1,Carmil1,Golga3,Hivep2,Prdm9,Rabgef1,Dusp4,Anp32a,Isg20,Hinfp,Olr1,Shfl,Itpkc,Rel,Arid4a,Hmox1,Phf11d,Stx6,N4bp1,Stat1,Timeless,Rgs14,Gpc1,Adar,Hck,Prdx5,Phlpp1,Med21,Nek6,Nfkbie,Stat5a,Pim1,Daxx,Lyn,Rnaset2b,Mier3,Rars,Tent4a,Mdm2,Riox2,Mcm10,Plagl1,Rilpl1,Spen,Rbpms,Tdrd7,Sap30,Egr2,Asf1a,Txnrd1,Jak2,Phf11c,Ciita,Rgcc,Irf8,Dtx3l,Bcorl1,Nxf1,Abtb2,Egr1,Maml2,Ifi204,Hsph1,Dtx2,Vps54,Gch1,Top3a,Tma16,Rrs1,Atm,Hspa2,Mtus1,Prdx1,Keap1,Mark2,Phf11b,Sh3bgrl2,Stap1,Ikzf1,Sp100,Ctsc,Etv5,Phf11a,Tcf4,Upp1,Snapc1,Plekha5,Jmjd6,Stk40,Dyrk2,Kdm6b,Oasl2,Ifi214,Rapgef5,Jun,Irf1,Zeb1,Cyth3,Il15,Mdn1,Klf2,Cx3cr1,Cdyl,Etnk1,Fam111a,Psmb6,Noc4l,P4ha2,Clic4,Bnip3,Ccdc86,Junb,Mafk,Syne2,Klf8,Sirt1,Agtrap,Oas2,Pou2f2,Ptpn2,Dr1,Kdm5b,Dse,Fos,Rcl1,Batf,Tasor2,Pml,Wdr43,Cnp,Trib3,Mpp7,Ptges,Dcp2,Rbl1,Tle3,Phlda1,Cdk5r1,Clcn7,Nmi,Arid5a,Tra2a,Tnks1bp1,Irf7,Gsdmd,Tfec,Fas,Cited2,Klf3,Taf4b,Eef1e1,Rai14,Itpr1,Sp140,Ciapin1,Mapkapk2,Ifi207,Higd1a,Klf6,Brd2,Aim2,Mndal,Myc,Cebpd,Rgs3,Hspa1b,Plk3,Cycs,Rnf34,Crkl,Parp3,Ppp4r2,Mecp2,Sbds,Dnajb4,Irf4,Nampt,Ifi209,Irf2,Pcgf5,Cenpj,Samhd1,Fubp1,Etv3,Hdac1,Psip1,Spata13,Nr1h3,Atf3,Gfi1,Alas1,Fosb,Cdkn1a,Aff1,Ak4,Casz1,Bbx,Asap3,Cox17,Sik3,Cutc,Nfkbiz,Zfp281,Nr3c1,Myo10,Phf6,Tulp3,Ier2,Tpx2,Jarid2,Zc3h12a,Ubr4,Crbn,Pdk3,Oas1b,Acsl5,Prpf4 |
| 9.636e-06 | -11.55 | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | MSigDB lists | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | 20 | 9 | 15632 | 1249 |
Mmp9,Egr1,Ccl12,Fos,Gem,Pdgfrb,Fgr,Tnc,Plau |
| 9.753e-06 | -11.54 | transition metal ion binding | molecular function | GO:0046914 | 950 | 101 | 20217 | 1400 |
Rnf145,Mt2,Trim36,Asah2,Mdm2,Dhx58,Dcp2,Plod2,Trim14,Prnp,Mefv,Ifih1,Lox,Jmjd6,Trim34a,Cpd,Slfn8,Fam20c,Mid1,Timp1,Lcn2,Zcchc2,Zswim4,Gpc1,Mmp25,Top3a,Trim13,Gch1,Mmp13,Dyrk2,Tet2,Traf2,Cutc,Pikfyve,Pml,Sec24b,Sod2,Mmp14,P4ha2,Trim12a,Cp,Car13,Extl2,Me1,Gda,Egln3,Morc3,Mt1,Phyh,Trim26,Nr1h3,Arg2,Kdm4a,Nr4a1,Mgat1,Rasgrp1,Tcea1,Ch25h,Egr1,Trim21,Znfx1,Apobec3,Slfn9,Trafd1,Plod3,Rnf24,Pim1,Lacc1,Ddx58,P4ha1,Nr3c1,Samhd1,Traf1,Smpdl3b,Lap3,Tnfaip3,Tnfsf10,Trim56,Tut7,Il1a,Birc2,Ubr4,Sec24a,Txnrd1,Setdb2,Kdm5b,Nr4a3,Trim30a,Rabgef1,Traf5,Sqstm1,Rnf139,Lnpep,Cox17,Ptch1,Dtx2,Acp5,Mmp9,Dtnb,Idi1,S100a8 |
| 9.798e-06 | -11.53 | GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_UP | MSigDB lists | GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_UP | 185 | 33 | 15632 | 1249 |
Tcf4,Phf11b,Atp13a1,Dock10,Rhoq,P2ry14,Nxf1,Kmo,Cd180,Atp11b,Mvp,Tap1,Dnase1l3,Phf11c,Cd38,Phf11a,Rnaset2a,Junb,Parp12,Dcp1a,Oas1a,St3gal5,Flnb,Pdss1,Zfp36,Isg20,Phf11d,Tgfbi,Ms4a6d,Oas1g,Mtdh,Rnaset2b,Tax1bp1 |
| 9.798e-06 | -11.53 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_UP | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_UP | 185 | 33 | 15632 | 1249 |
Ifit1bl2,Cd86,Tnfsf14,Cnp,Tor1aip1,Plscr1,Tlr1,Isg20,Syne2,G3bp2,Xkr8,Il18,Ier3,Ikbke,Rsbn1,Abcc1,Zhx2,Wdr43,Cmpk2,Ass1,Ifit1bl1,Parp8,Ttc39c,Myc,Slc15a3,Fcgr2b,Taf4b,Sell,Batf,Mdfic,Ifit1,Hvcn1,Aff1 |
| 9.798e-06 | -11.53 | GSE40273_GATA1_KO_VS_WT_TREG_DN | MSigDB lists | GSE40273_GATA1_KO_VS_WT_TREG_DN | 185 | 33 | 15632 | 1249 |
Ciita,Relb,Ahr,Usp25,Malt1,Kmo,Hif1a,Lrch1,Ogfrl1,Phlpp1,Hdac1,Syk,Parp8,Slc25a37,Rhof,Gpr18,Itpr1,Clcf1,Parp3,Filip1l,Cd200,Map3k8,Arid5b,Tmem229b,Wdfy1,Zeb1,Vasp,Sesn3,Card6,Birc3,Snx10,Plek,Hopx |
| 9.798e-06 | -11.53 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_UP | 185 | 33 | 15632 | 1249 |
Fos,Bcl6,Cited2,Tnf,Nr4a1,Ifrd1,Mdm2,Ccng2,Pdpn,Cd74,Il1a,Ier2,Rars,Mxd1,Nfkbiz,Ube2f,Il10,Sema3c,Zc3h12c,Map2k1,Gem,Dach1,Junb,Ccl5,Brwd3,Cxcl2,Vasp,Ampd3,Rac3,Uchl1,Glrx,Gfi1,Cxcl1 |
| 9.798e-06 | -11.53 | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | 185 | 33 | 15632 | 1249 |
Psip1,Sod2,Ifi213,Ifi205,Tcf4,Ifi209,Dse,Sdc2,Slc30a4,Ifi214,Prnp,Kat2b,Extl2,Crim1,Ifi207,Pdgfc,Rgl1,Mndal,Flrt2,Cav1,Ppm1k,Htra1,Ifi208,Procr,Ifi211,Ifi203,Ube2e2,Map3k8,Ifi204,Gca,Kdr,Rbms1,Dcbld2 |
| 9.798e-06 | -11.53 | GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN | MSigDB lists | GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN | 185 | 33 | 15632 | 1249 |
Uba7,Dgka,Snx2,H2-Aa,Zfp36,Caml,Atp6v1d,Casp4,Pde4b,Snx10,Eif4g2,Bcl2a1a,Cflar,Ttc39b,Ms4a6d,Dnaja2,Casp7,Bcl2a1d,Slc44a1,Ppp2r5a,Psmb9,Cyfip1,Bcl2a1b,Abcc5,Casp1,Dusp1,Tap1,Traf5,Cd83,Nxf1,Sell,Atp11a,Fas |
| 9.798e-06 | -11.53 | GSE11057_CD4_CENT_MEM_VS_PBMC_DN | MSigDB lists | GSE11057_CD4_CENT_MEM_VS_PBMC_DN | 185 | 33 | 15632 | 1249 |
Mxd1,Tlr6,Cd180,Fpr2,Myd88,Hvcn1,Pdgfc,Rab32,Aoah,Cyfip1,Rhbdf2,Oaf,Slc15a3,Rhoq,Igsf6,Ogfrl1,B3gnt5,Dram1,Rtn1,Grina,Ptafr,Acsl1,Sema4a,Cmklr1,Jak2,Fmnl2,Prkar2b,Slc31a2,Plek,Dusp6,Tnfsf15,Gbgt1,Snx2 |
| 9.889e-06 | -11.52 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP | 145 | 28 | 15632 | 1249 |
Snx10,Ankib1,Ttc9c,Cd274,Bcl9,St3gal5,Rasgrp1,Spint2,Kctd12,Ptgir,Ripk2,Osgin2,Cflar,Slc37a3,Trafd1,Eif2ak2,Dhrs9,Bcl2l11,Slc7a11,Mtus1,Ctsc,Casp3,Rab11fip1,Cish,Treml2,Ift57,Il4ra,Socs1 |
| 9.990e-06 | -11.51 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP | 177 | 32 | 15632 | 1249 |
Psip1,Pde5a,Lrp8,Plagl1,Hif1a,Sla,Slc16a1,Ncoa7,Ripk3,Enpp4,Mthfd1l,Psat1,4933430I17Rik,Ascc3,Pdgfrb,Ptch1,Trip13,Pdss1,St3gal5,Kctd12,Fam72a,Il18rap,Traf3ip2,Atp10a,Ebi3,Rcsd1,Tmem229b,Ms4a6d,Osbpl3,Gfpt1,Pkp4,Plaur |
| 9.990e-06 | -11.51 | GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP | MSigDB lists | GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP | 177 | 32 | 15632 | 1249 |
Hlx,Cdkn2d,Rhoh,Enpp4,Klf7,Crim1,Cd38,Relb,Hck,Tnfaip3,Dnase1l3,P4ha2,Rapgef5,Ankrd17,Sat1,Optn,Gadd45g,Cebpd,Cd55,Kdm6b,Pim2,Cxcl1,Rnf14,Psd4,Rims3,Bcl9,St3gal5,Zfp36,Oas2,Cd69,Spint2,Cxcl2 |
| 9.990e-06 | -11.51 | GSE22033_UNTREATED_VS_ROSIGLITAZONE_TREATED_MEF_DN | MSigDB lists | GSE22033_UNTREATED_VS_ROSIGLITAZONE_TREATED_MEF_DN | 177 | 32 | 15632 | 1249 |
Mdm2,Ccnd1,Bcl2a1d,Irf4,Myc,Ifi44,Ets2,Ifit2,Nfkbia,Bcl2a1b,Bcl2l11,Dhrs9,Cst7,Clcn5,Tnfaip3,Rbms2,Stat2,Ddx58,Nxf1,Malt1,Lif,Spen,Cav1,Sik3,Birc3,Pdk3,Pmepa1,Bcl2a1a,Nfkb2,Arid5b,Ifi35,C3 |
| 1.005e-05 | -11.51 | GAL_LEUKEMIC_STEM_CELL_DN | MSigDB lists | GAL_LEUKEMIC_STEM_CELL_DN | 227 | 38 | 15632 | 1249 |
Phlda1,Stx11,Ccl5,Ccr1,S100a8,Adap2,Cd86,Ccl4,Il1rn,Il1b,Ell2,Mmp9,Tlr2,Fpr1,Clec5a,Osgin2,Ms4a6d,Igsf6,Egr2,Slc15a3,Minpp1,Cebpd,Vcan,Fgl2,Casp1,Nr4a1,Aoah,Cx3cr1,Gpr18,Cd14,Pilra,Samhd1,Cd38,Col18a1,Tpi1,Prdm1,Fgr,Dmxl2 |
| 1.005e-05 | -11.51 | PLASARI_TGFB1_TARGETS_10HR_DN | MSigDB lists | PLASARI_TGFB1_TARGETS_10HR_DN | 227 | 38 | 15632 | 1249 |
Kitl,Il1rn,Pcdh7,Vcam1,Prkar2b,Glrx,Fmnl2,Stat1,Herc6,Il18,Arid5b,Serpinb9,Ifit3b,Ampd3,Nmi,Trim21,Eya4,Tshz1,Sesn3,Ednrb,Ifit1bl2,Plek,Cenpj,Plekhg1,Ifit3,Pbx1,Cdc42ep2,Rnd3,Rtp4,Usp18,Phip,Parp9,Nqo1,Pde5a,Ifit1bl1,Adhfe1,Ifit2,Eif2ak2 |
| 1.011e-05 | -11.50 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_UP | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_UP | 169 | 31 | 15632 | 1249 |
Fscn1,Acp2,Ebi3,Mmp9,C3,Tnip3,Slamf8,Tgfbi,Tmeff1,Procr,Rtn2,Inhba,Ltbp2,Flrt2,Rrs1,Etv5,Crim1,Magohb,Stxbp1,Lrp8,Ccl22,Nr1h3,Minpp1,Fut8,Fcgr2b,Pdpn,Ccdc86,Mmp14,Cish,Scarf1,Agrn |
| 1.011e-05 | -11.50 | GSE6259_BCELL_VS_CD8_TCELL_UP | MSigDB lists | GSE6259_BCELL_VS_CD8_TCELL_UP | 169 | 31 | 15632 | 1249 |
Inpp1,Cldnd1,Lacc1,Kif5c,Sema4a,Spata5l1,Ddit4,Btg2,Rhou,Rgl1,Ahrr,Itgal,Tnfsf14,Ptch1,Plau,Gng11,Daxx,Egr1,Kat2b,Arg2,Setdb2,Mmp14,Prdx5,Gpr68,Rsad2,Slc7a11,Ccl12,Ddhd1,Ttc39c,Ets2,Tiparp |
| 1.011e-05 | -11.50 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_UP | 169 | 31 | 15632 | 1249 |
Usp12,Hk2,Fcgr4,Ccr1,P4ha1,Daam1,Sema3c,Plod2,Serpine1,Il1rn,Bcl2a1a,Plaur,Pkp4,Armc8,Pf4,Tfec,Hmox1,Kif5c,Spry2,Rai14,Vcan,Bcl2a1d,P4ha2,Bcl2a1b,Timp1,Tiparp,Hk3,Mdfic,Rars,Slc30a1,Aldh1b1 |
| 1.015e-05 | -11.50 | regulation of interleukin-8 production | biological process | GO:0032677 | 61 | 15 | 20694 | 1406 |
Tlr3,Ptger4,Tlr6,Serpine1,Nod2,Ddx58,Tnf,Mapkbp1,Tlr2,Tlr9,Il18,Myd88,Cd14,Il1b,Tlr1 |
| 1.027e-05 | -11.49 | positive regulation of T-helper 1 type immune response | biological process | GO:0002827 | 23 | 9 | 20694 | 1406 |
Il1b,Il12b,Arid5a,Il12rb1,Hlx,Ripk2,Irf1,Il18,H2-Ab1 |
| 1.027e-05 | -11.49 | cellular response to dsRNA | biological process | GO:0071359 | 23 | 9 | 20694 | 1406 |
Cgas,Ddx58,Mul1,Cav1,Zc3hav1,Ifih1,Ifnb1,Nfkb1,Tlr3 |
| 1.033e-05 | -11.48 | TRAF6 mediated IRF7 activation | REACTOME pathways | R-MMU-933541 | 23 | 10 | 8608 | 757 |
Ifna4,Irf7,Ifna6,Irf2,Irf1,Ifna1,Ifna2,Ifna5,Ifnb1,Myd88 |
| 1.033e-05 | -11.48 | negative regulation of response to cytokine stimulus | biological process | GO:0060761 | 54 | 14 | 20694 | 1406 |
Rffl,Mul1,Cav1,Rabgef1,Adar,Ccl5,Nlrc5,Il6,Stap1,Parp14,Il1rn,Samhd1,Irak3,Ptpn2 |
| 1.034e-05 | -11.48 | regulation of system process | biological process | GO:0044057 | 597 | 69 | 20694 | 1406 |
Tnf,Hopx,Cx3cl1,Adora2a,Il1a,Rab11fip1,Cacna1d,Mmp13,Abcb1a,Mecp2,Ptger4,Atp2b4,Gch1,Acpp,Il10,Gpr35,Slc9a1,Adrb2,Hcar2,Dock4,Icam1,Calcrl,Edn1,Homer1,Nlgn2,S1pr2,Agrn,Nr1h3,Cst7,Ptk2,Fcgr4,Ednrb,Pde5a,Pde4b,Htr2a,Ptgs2,Ptafr,Hif1a,Arg2,Il6,Scn1b,Pdgfb,Lif,Ctsc,Map2k1,Adora2b,Kcnj2,Jarid2,Src,Dusp5,Cd38,Cacnb3,Nr3c1,Ahr,Nr4a3,Cav1,Inhba,Jak2,Gja1,Errfi1,Sphk1,Il1b,Notch1,Trip10,Tnfrsf1b,Zc3h12a,Sirt1,Mdm2,Tomm70a |
| 1.048e-05 | -11.47 | WGTTNNNNNAAA_UNKNOWN | MSigDB lists | WGTTNNNNNAAA_UNKNOWN | 482 | 66 | 15632 | 1249 |
Prdm1,Hlx,Zfp513,Zfp281,Arg2,Dtx3l,Rnf34,Sgk3,Rgs3,Etv5,Prpf38a,Gypc,Bcl6,Tcf4,Birc2,Cish,Rhoq,Mecp2,Glipr2,Fndc3a,Gpr85,Nr4a3,Cdc42ep4,Pcdh7,Tfec,Zhx2,Hcar2,Jarid2,Ccr1,Dusp6,Gch1,Flrt2,Pdgfb,Ext1,Slc7a5,Ppp2r3a,Bcor,Tmtc2,Trim13,Arl4a,Klf7,Mark2,Klf3,Tet2,Fos,Gpr18,Ets2,Vcan,Rin2,Itpkc,Dnajb4,Trib1,Ier3,Rgs1,Col27a1,Igf1r,Cdkn1a,Il10,C1rl,Lmo4,Med13,Hivep3,Ube2e2,Dcp1a,Syne2,Cd69 |
| 1.051e-05 | -11.46 | GO_MACROMOLECULAR_COMPLEX_BINDING | MSigDB lists | GO_MACROMOLECULAR_COMPLEX_BINDING | 1278 | 144 | 15632 | 1249 |
Fgr,Icam1,Hif1a,Mthfr,Apba1,H2-Q7,Hhex,Myo10,Relb,Mcmbp,Notch1,Ripk3,Rgs14,Psmb9,Src,Mlkl,Acvrl1,Ccnd1,Lztfl1,Acvr1,Dbnl,Egr2,Casp3,Kif3c,Tapbpl,Pim1,Tgfbi,Zc3h12a,Kdm6b,Thbs1,Myo1b,Plk2,Jarid2,Ifna6,Antxr1,Pdgfb,Phip,Prnp,Lrp8,Htr2a,Fcgr1,Ciita,Hinfp,Ifna1,Jun,Fos,Msr1,Cyfip1,Pik3r5,Sbds,Bcl2l11,Nfkbia,Rab32,Ezr,H2-Q4,Cenpe,Triobp,Ncoa5,Myc,Adrb2,Acvr1b,Kif5c,Igf1r,Asf1a,Kdr,Hcls1,Cflar,Actb,Ptch1,Itgal,Gna15,Ccne1,Sirt1,Ep400,Ifih1,Rnf135,Cd74,Tulp3,Nupr1,Ifna2,Gnb4,Ankrd17,Bcl6,H2-Q6,Traf2,Ythdf1,Mecp2,Hdac1,Micall2,Stat3,Phf6,Ppp2r2a,Nfkb2,Vcam1,Brd2,Hsd17b12,Fcgr4,Mmp13,Snx2,Cx3cl1,Irs2,Kat2b,Fas,Kif9,Hmga1,Cited2,Ptpn2,Syk,Psip1,Plac8,Mid1,Ifna5,Scarf1,Ifnb1,S1pr2,Katna1,Mmp14,Fcgr2b,Rcsd1,Lyn,Itga9,Mmp9,Itga5,Max,Cpeb4,Cdkn1a,Dnajb2,Wdr43,H3f3b,Lhx2,Ldlr,Whamm,Fscn1,Cep350,Casp8,Rel,Jdp2,Nfkb1,S100a8,Atm,Syne2,Rictor,Zeb1,Cnn3 |
| 1.052e-05 | -11.46 | negative regulation of necrotic cell death | biological process | GO:0060547 | 18 | 8 | 20694 | 1406 |
Birc2,Peli1,Rnf31,Ahr,Cflar,Casp8,Cav1,Birc3 |
| 1.052e-05 | -11.46 | macrophage migration | biological process | GO:1905517 | 18 | 8 | 20694 | 1406 |
Cx3cl1,Ccl12,Ccl3,Cx3cr1,Ednrb,Gpr35,Ccl2,Mcoln2 |
| 1.052e-05 | -11.46 | regulation of natural killer cell differentiation | biological process | GO:0032823 | 18 | 8 | 20694 | 1406 |
Irf1,Prdm1,Il15,Rasgrp1,Axl,Stat5a,Lgals9,Il15ra |
| 1.062e-05 | -11.45 | BROWNE_HCMV_INFECTION_14HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_14HR_DN | 262 | 42 | 15632 | 1249 |
Rbpms,Cebpd,Pde5a,Pdpn,Prkce,Gpsm2,Axl,Spn,Cenpe,Apobec3,Casp1,Ccl12,Mvp,Myo10,Sgcb,Rras2,Plau,Gng11,Tulp3,Nr1h3,Papss2,Psmb10,Socs1,Fas,Irf2,Slc25a12,Met,Ext1,Myo1b,Serpine1,Vegfc,Plaur,Abcc1,Glrx,Actb,Notch2,Ldlr,Thbs1,Lpar1,Pik3cd,Il12b,Traf3ip2 |
| 1.063e-05 | -11.45 | Pathways in cancer | KEGG pathways | mmu05200 | 391 | 61 | 7931 | 713 |
Met,Myc,Fzd5,Hif1a,Egln3,Vegfc,Rac3,Ikbkg,Crkl,Ccnd1,Slc2a1,Gng4,Kitl,Ralgds,Bmp2,Cycs,Casp3,Gng11,Pik3cd,Gng12,Traf2,Casp8,Ccne1,Nfkbia,Mmp9,Fas,Itgav,Nos2,Ptk2,Map2k1,Hdac1,Cdkn1a,Lpar1,Pdgfrb,Rasgrp1,Nfkb2,Ptger4,Il6,Birc3,Fos,Mdm2,Col4a2,Csf3r,Igf1r,Stat5a,Pml,Gnb4,Traf5,Ptgs2,Ednrb,Stat3,Birc2,Traf1,Nfkb1,Jun,Stat1,Fzd1,Akt3,Max,Pdgfb,Ptch1 |
| 1.066e-05 | -11.45 | positive regulation of cytoskeleton organization | biological process | GO:0051495 | 207 | 32 | 20694 | 1406 |
Cenpj,Cyfip1,Mecp2,Cx3cl1,Lpar1,Fchsd2,Vasp,Cdc42ep2,Cdc42ep4,Met,Hck,Plek,Csf3,Whamm,Evl,Nck1,Sdc4,Dync1h1,Stap1,Edn1,Spire1,Prkce,Rgcc,Icam1,Rictor,Cav1,Carmil1,Swap70,Rac3,Rhoc,Gpsm2,Gda |
| 1.068e-05 | -11.45 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | 30 | 11 | 15632 | 1249 |
Traf2,Irf7,Hspa1a,Axl,Nlrc5,Csf1,Edn1,Cd74,Hif1a,Ripk2,Gfi1 |
| 1.069e-05 | -11.45 | SH2_dom_sf | interpro domains | IPR036860 | 111 | 22 | 19984 | 1430 |
Rin2,Src,Syk,Sla,Tyk2,Stat3,Lcp2,Socs3,Stat1,Cish,Stat2,Socs1,Stat4,Socs7,Jak2,Stap1,Stat5a,Lyn,Fgr,Hck,Nck1,Crkl |
| 1.090e-05 | -11.43 | GO_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | MSigDB lists | GO_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | 53 | 15 | 15632 | 1249 |
Ripk3,Il1b,Tnfsf4,H2-Q7,Malt1,Nlrp3,Il12b,Il12rb1,Rsad2,Ifnb1,H2-Q4,Spn,Fzd5,Traf2,H2-Q6 |
| 1.096e-05 | -11.42 | cellular response to hypoxia | biological process | GO:0071456 | 84 | 18 | 20694 | 1406 |
Pdk3,Notch1,Sirt1,Slc9a1,Bnip3,Myc,Adrb2,Egr1,Plk3,Rgcc,Prkce,Vasn,Fam162a,Pgk1,Higd1a,Hif1a,Cited2,Ak4 |
| 1.096e-05 | -11.42 | interaction with host | biological process | GO:0051701 | 84 | 18 | 20694 | 1406 |
Itgav,Tlr2,Serpinb9,Irgm2,Tnip1,Cav1,Tnfrsf14,Mmp9,Bcl2l11,Nectin4,Clec5a,Irgm1,Myc,Cd300lf,Nectin2,Cd55,Axl,Pvr |
| 1.096e-05 | -11.42 | regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0000079 | 84 | 18 | 20694 | 1406 |
Actb,Src,Ccnj,Hhex,Ccne1,Cdkn1a,Ccnd2,Casp3,Pdgfb,Pim1,Ccnd1,Rgcc,Psmd10,Cdk5r1,Ccng2,Tnfaip3,Kat2b,Cdkn2d |
| 1.097e-05 | -11.42 | GO_NAD_ADP_RIBOSYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_NAD_ADP_RIBOSYLTRANSFERASE_ACTIVITY | 25 | 10 | 15632 | 1249 |
Parp14,Parp12,Parp9,Zc3hav1,Sirt1,Parp3,Parp10,Parp8,Tiparp,Parp11 |
| 1.097e-05 | -11.42 | PID_TOLL_ENDOGENOUS_PATHWAY | MSigDB lists | PID_TOLL_ENDOGENOUS_PATHWAY | 25 | 10 | 15632 | 1249 |
Vcan,Tlr1,Irak2,Cd14,Myd88,Tlr2,Tlr6,Ikbkg,S100a8,Tlr3 |
| 1.098e-05 | -11.42 | macromolecule metabolic process | biological process | GO:0043170 | 5178 | 420 | 20694 | 1406 |
Tcea1,Sphk1,Jak2,Rictor,Pgk1,Inhba,Tnfaip3,Irf7,Tyk2,Rnf139,Spsb1,Akt3,Lif,Flt1,Usp12,Tnfsf15,Ube2e1,Psma6,Gpc1,Wdr43,Dpy19l1,Nr3c1,Nxf1,Phlda1,Peli1,Map2k1,Pdk3,Trim12c,Eif4g2,Dusp14,Zc3h7a,Dnajb2,Snapc1,Ccng2,Il15,Nupr1,Pdgfrb,Ptpn2,Ptk2,Prag1,Gbe1,Kdm5b,Prkx,Fosb,Herc6,Eef1e1,Arid4a,Apobec3,Rnf34,Slfn9,Ascc3,Stat5a,Ppm1k,Map3k8,Pnpt1,Eif2ak2,Gtpbp2,Arrdc4,Dcp2,Psmb9,Med21,Batf,Psmb8,Birc3,Tlr3,Plat,Ifnar1,Ppm1l,Ppp2r5a,Keap1,Prkce,Cdk5r1,Btg2,St3gal5,Mlkl,Polr2g,Tet2,Trib3,Pim3,Isg15,Sla,Acp2,Il1b,Acvr1b,Pgap2,Dusp1,Otud1,Mcm9,Lox,Saa3,Ube2l6,Cpeb4,Casp2,Bmp2,Tmem67,Srgn,Bnip3,Tra2a,Psmb10,Agrn,Sik3,Dusp6,Rffl,Rnf19a,Nck1,Acvrl1,Trim56,Rbbp8,Denr,Casp8,Uba7,Gys1,Crbn,Top3a,Sbds,Usp53,Il18,Fgl2,Mdn1,Zc3h12a,Mocs1,Chmp4b,Nek6,Usp25,Traf2,Stk40,Mul1,Ripk2,Mvp,Rnf14,Tut7,B3gnt5,Casp4,Hivep2,Casp1,Jarid2,Ccne1,Rrs1,Rnaset2a,Ldlr,Smg7,Trip13,Socs7,Hmga1,Fas,Ube2f,Nsd3,Svbp,Dtx3l,Usb1,Ep400,Lnpep,Irf4,Sgk3,Mmp14,C1ra,Mtmr14,Ccr3,Casp7,Med13,Usp42,Hspa1a,Naa25,Rars,Phlpp1,Pigv,Klhl25,Asf1a,Il10,Map2k4,Ppp1r15b,St3gal3,Osm,Cav1,Trim30a,Ctu1,Arel1,Mmp9,Sirt1,Ddx4,Nfil3,Ksr1,Mmd,Mgat1,Dusp5,Sde2,F10,Ppp2r2a,Marf1,Mrpl52,Nlgn2,Dr1,Kat2b,Jmjd6,Uchl1,Hk1,P4ha1,Parp3,Adgb,Rnf135,Tcf4,Jun,Pcgf5,Tnf,Lap3,Plk3,Mapkbp1,Dse,Angpt1,Prpf38a,Armc8,St3gal6,Cpd,Taf4b,Parp10,Ccl12,Caml,Hat1,Stat1,Bcor,Usp35,Il12rb1,Trib1,Ripk3,Mcm10,Adar,Dnase1l3,Swap70,Mcm6,Ranbp2,Pdgfb,P4ha2,Ero1l,Ikbke,Fam111a,Tnks1bp1,Hck,Stat3,Parp12,Src,Rbms1,Tpst1,Ifih1,Dusp16,Birc2,Aff1,Myc,Dcp1a,Ppp4r2,Rnf19b,Dcun1d3,Mecp2,Usp31,Znrf3,Trim12a,Hopx,Ell2,Tlr9,Parp8,Parp14,Ezr,Scyl2,St3gal1,Itgav,Cemip2,Casp3,Ccnd1,Extl2,Mdm2,Mppe1,Mapkapk2,Pttg1,Ppp2r3a,Hmga2,Tmtc2,Dtx2,Kdm4a,Hif1a,Ccnd2,Cflar,Sap30,Dusp8,Grk3,Slfn8,Prdm9,Thbs1,Plk2,Trem1,Fbxo4,Prnp,Ubr4,Ctsc,Samhd1,Fut8,Ube2e2,Kmt5a,Ext1,Zhx2,Calcrl,Egr1,Mmp25,Dusp4,Plod3,Ppp1r15a,Plod2,Mark2,Cnot4,Kdm6b,Cgas,Ubash3b,Gfpt1,Phlpp2,Setdb2,Kdr,Egr2,Magohb,Mdfic,Serp1,Rcl1,Myd88,Met,Vcpip1,Znrf1,Lipe,Plpp1,Tlr2,Pim1,Tiparp,Irak2,Htra1,Mcmbp,Irgm2,Parp9,Endod1,Smc5,Nos2,Trmt1l,Map4k4,Gcnt2,Dyrk2,Icosl,Aoah,Ptprj,Nmi,Tlk2,Tent2,Xrn1,Trim21,Gadd45g,Irak3,Zfp36,Cop1,Morc3,Mov10,Ptger4,Tgs1,Mmp13,Egln3,Yju2,Hdac1,Plau,Adam19,S100a8,Hinfp,Acvr1,Helz2,Usp18,Lmo4,Ptch1,Htr2b,Tnip1,Chst11,Lyn,C1rl,Parp11,Ahr,Arf4,Fam20c,Axl,Trim13,Hhex,Atm,Tent4a,Olr1,Fos,Rnaset2b,Ankib1,Timeless,Cdyl,Isg20,Dusp2,Larp1,Igf1r,Psip1,Vrk2,Fgr,Map3k6,Wars,Cdkn2d,Nod1,Ccl5,Psmb6,Oas2,Rnf31,Junb,Prpf4,Malt1,Dusp28,Syk,Stat4,Trim36,Bfar,Noct,Col4a2,Pml,Pim2,Zc3h12c,Ago3,Eya4,Ccnj |
| 1.102e-05 | -11.42 | KIM_WT1_TARGETS_12HR_DN | MSigDB lists | KIM_WT1_TARGETS_12HR_DN | 186 | 33 | 15632 | 1249 |
Myc,Bcl2a1d,Ccnd1,Sod2,Bcl2a1b,Gadd45b,Dusp1,Plac8,Ezr,Rnd3,Olr1,Crim1,Lrp8,Cdk5r1,Plscr1,Phlda1,Ext1,Inhba,Nfkb1,Ogfr,Plod2,Casp4,Rrs1,Sema3c,Flrt2,Plk2,Thbs1,Rap2c,Kitl,Bcl2a1a,Pmepa1,Armc8,Il18 |
| 1.102e-05 | -11.42 | GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_UP | MSigDB lists | GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_UP | 186 | 33 | 15632 | 1249 |
Cd55,H2-Ab1,Egr3,Psmb6,Cacnb3,Il2rg,Polr2g,Prkar2b,Cdkn1a,S100a8,Junb,Asns,Tnfsf14,Itgal,Pdgfb,Psme2,H2-Aa,Wars,Bst1,Ier2,Marcksl1,Ccl22,Psmb10,Jmjd6,Fgr,Fcgr1,Gbp2,Spn,Dusp1,Psmb9,Tmem184b,Fgl2,Tapbp |
| 1.102e-05 | -11.42 | GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_UP | 186 | 33 | 15632 | 1249 |
Rras2,Traf5,Cd83,Ch25h,Marcksl1,Aldh1b1,Irf4,Dock10,Cers6,Pcx,Sele,Tra2a,Txnrd1,Ccl12,Ezr,Gadd45b,Hmga1,Tmem184b,Homer1,Htr2b,Pfkl,Smox,Kpna3,Mcm6,Kcna3,Trib1,Flnb,Slc7a5,Slc39a14,Brd2,Clic5,Asns,Rel |
| 1.102e-05 | -11.42 | GSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_DN | MSigDB lists | GSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_DN | 186 | 33 | 15632 | 1249 |
Abcc1,Wdr43,Hsd17b7,Gfpt1,Arf4,Ldlr,Cd82,Odc1,Spata5l1,Larp1,Dgkh,Dnaja2,Eef1e1,Hk2,Rasgrp1,AA467197,Slc7a5,Noc4l,Fubp1,Gem,Hsd17b12,Tuba4a,Etv5,Spred1,Pim3,Slamf7,Pikfyve,Lrp8,Dusp4,Myc,Mrpl52,Tnf,Srm |
| 1.106e-05 | -11.41 | Guanylate-bd/ATL_C | interpro domains | IPR003191 | 13 | 7 | 19984 | 1430 |
Gbp8,Gbp3,Gbp7,Gbp2b,Gbp4,Gbp9,Gbp2 |
| 1.108e-05 | -11.41 | positive regulation of gliogenesis | biological process | GO:0014015 | 92 | 19 | 20694 | 1406 |
Crkl,Lif,Il6,Lyn,P2ry12,Tspo,Clcf1,Tlr2,Csf1,Tnf,Hdac1,Myc,Tnfrsf1b,Ptk2,Fubp1,Notch1,Etv5,Il1b,Bmp2 |
| 1.108e-05 | -11.41 | divalent inorganic cation homeostasis | biological process | GO:0072507 | 509 | 61 | 20694 | 1406 |
Ednrb,Fpr1,Bnip3,Htr2a,Ptgir,Ccr3,Ccrl2,Edn1,Cd40,Atp13a1,Cxcl2,Ccl5,Gpr35,Ccl2,Slc30a1,Adrb2,Cx3cr1,Ccr1,Pml,Kdr,Cmklr1,Ptger4,Atp2b4,Mt2,Cx3cl1,Ccl3,P2ry2,Cacna1d,Cxcl1,Swap70,Il1b,Tmtc2,Slc39a14,Grina,Jak2,Itgav,Slc39a4,Htr2b,Itpr1,Gja1,Slc30a4,Marcksl1,Gpr18,Prkce,Cav1,Cxcl3,Slc39a13,Cd38,Mt1,Cacnb3,Hap1,Fpr2,Snx10,Xcr1,Cxcl10,Ero1l,1600014C10Rik,Tmem178,Gna15,Rmdn3,Lpar1 |
| 1.115e-05 | -11.40 | GO_CHEMOKINE_RECEPTOR_BINDING | MSigDB lists | GO_CHEMOKINE_RECEPTOR_BINDING | 47 | 14 | 15632 | 1249 |
Cxcl14,Cxcl2,Ccrl2,Ccl2,Stat3,Ccl5,Ccl12,Pf4,Ccl3,Ccl4,Cxcl1,Cx3cl1,Cxcl10,Ccl22 |
| 1.115e-05 | -11.40 | DELACROIX_RAR_TARGETS_UP | MSigDB lists | DELACROIX_RAR_TARGETS_UP | 47 | 14 | 15632 | 1249 |
Gsr,Tyk2,Mllt6,Cp,Sat1,Hmga1,Dusp6,Dusp1,Junb,Lipe,Esd,Zbp1,Atp11a,Nupr1 |
| 1.121e-05 | -11.40 | MAPK cascade | biological process | GO:0000165 | 170 | 28 | 20694 | 1406 |
Ptk2,Mapkapk2,Ccr3,Il1b,Myc,Mlkl,Il18,Zfp36,Ppm1l,Trib1,Ccl5,Map3k6,Itgav,Htr2b,Map2k4,Map2k1,Ccl12,Map4k4,Myd88,Map3k8,Mul1,Ripk2,Mdfic,Tnf,Mapkbp1,Syk,Ptger4,Kdr |
| 1.126e-05 | -11.39 | GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_UP | MSigDB lists | GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_UP | 178 | 32 | 15632 | 1249 |
Aim2,Ier2,St3gal6,Socs1,Nxf1,Tab2,Pfkfb3,Ppfibp1,Bcl2l11,Plac8,Flt1,Timp1,Il6,Irf4,Nr3c1,Micall2,Socs3,Kdm6b,Azi2,Rcn1,Rgs1,Cd82,Il1rn,Cmklr1,Arf4,Tnfrsf1b,Junb,Tnfsf14,Ppp1r15a,Slc7a5,Dcp1a,G3bp2 |
| 1.126e-05 | -11.39 | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | 178 | 32 | 15632 | 1249 |
Il18rap,Il12rb1,Ksr1,Slfn4,Sesn3,Tnfrsf1b,Cldnd1,Thbs1,Ust,Slfn3,Arid5b,Pdzd11,Tnip3,Cacnb3,Oasl1,Zc3h12a,Optn,Chst11,Pde1b,Dusp2,Rhbdf2,Ezr,Crim1,Sav1,Batf,Slco3a1,Nlrp3,Mapkapk2,Lrp8,Fas,Aim2,Abr |
| 1.126e-05 | -11.39 | GSE27786_LIN_NEG_VS_CD4_TCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_CD4_TCELL_DN | 178 | 32 | 15632 | 1249 |
Cept1,Ikzf1,Tet2,Rgs14,Arid5a,Nlrc5,Sqstm1,Mark2,Clcn5,Tap1,Ccdc88b,1600014C10Rik,Nkiras1,Trim12c,Rtp4,Slc30a1,Psme1,Slc39a14,Cysltr2,Nmi,Itgal,Irf7,Ankib1,Tnfrsf1b,Glrx,Ppp2r2a,Sec24b,Pmepa1,Cflar,Chic2,Azi2,Socs3 |
| 1.132e-05 | -11.39 | GO_CELLULAR_RESPONSE_TO_EXOGENOUS_DSRNA | MSigDB lists | GO_CELLULAR_RESPONSE_TO_EXOGENOUS_DSRNA | 12 | 7 | 15632 | 1249 |
Ifnb1,Zc3hav1,Tlr3,Ifit1bl2,Ifit1bl1,Cav1,Mul1 |
| 1.132e-05 | -11.39 | LEE_SP4_THYMOCYTE | MSigDB lists | LEE_SP4_THYMOCYTE | 12 | 7 | 15632 | 1249 |
Egr3,Ier3,Spry2,Irak2,Rsad2,Dusp4,Htr2b |
| 1.134e-05 | -11.39 | immune response-activating cell surface receptor signaling pathway | biological process | GO:0002429 | 143 | 25 | 20694 | 1406 |
Rnf31,Pde4b,Fpr1,Malt1,Zc3h12a,Crkl,Nfkbiz,Lcp2,Nfkbid,Lyn,Themis2,Tlr2,Nr4a3,Dennd1b,Cacnb3,Spn,Cd38,Icosl,Fpr2,Fcgr2b,Klrk1,Syk,Cmklr1,Bcl2a1d,Ripk2 |
| 1.136e-05 | -11.39 | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | MSigDB lists | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | 254 | 41 | 15632 | 1249 |
Irs2,Intu,Ccnd2,Sdc1,Tulp3,Csrnp1,Prdm1,Dusp14,Atp2b4,Rgs3,Extl2,Cited2,Tpst1,Cers6,Chst11,Stard5,Irf4,Rab20,Trib1,Cacnb3,Uaca,Ppa1,Fndc3a,Ell2,Mtdh,Abcc1,Nfil3,Dusp16,Igf1r,Sec24a,Sh3bgrl2,Asns,Spint2,Hivep3,Eya4,Smpdl3b,Slamf9,Antxr1,Slc7a5,Phlda1,Btg2 |
| 1.139e-05 | -11.38 | IL1BCENZYME | prints domains | PR00376 | 10 | 6 | 5821 | 374 |
Casp2,Casp3,Casp4,Casp1,Casp7,Casp8 |
| 1.151e-05 | -11.37 | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_DN | 162 | 30 | 15632 | 1249 |
Vrk2,Dusp16,H3f3b,Thbs1,Fpr1,Azi2,Irf1,Usp35,Pou2f2,Bst1,Tlr1,Isg20,Sik3,Casp4,Flrt2,Pid1,Dusp6,Card6,Pde4b,Tnfrsf8,Clec4e,Crlf3,Cyth3,Nfkbiz,Mlkl,Vcan,Dse,Casp1,Pik3r5,Sod2 |
| 1.151e-05 | -11.37 | GSE20727_CTRL_VS_H2O2_TREATED_DC_DN | MSigDB lists | GSE20727_CTRL_VS_H2O2_TREATED_DC_DN | 162 | 30 | 15632 | 1249 |
Actb,Clcf1,Rnaset2b,Kif5c,Ebi3,Ptk2,Asb13,Ifit3b,Aida,Flnb,Stxbp3,Xaf1,Junb,Pdk3,Adap2,Ppm1k,Rnaset2a,Ifit3,Hck,Zc3hav1,Apaf1,St3gal3,Nek6,Cdk5r1,Psip1,Lipe,Stat5a,Nr4a1,Slc25a37,Crbn |
| 1.151e-05 | -11.37 | GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP | MSigDB lists | GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP | 162 | 30 | 15632 | 1249 |
Jarid2,Sesn3,Usp12,Rnf19a,Ext1,Rnf145,St3gal1,Dck,Dtx2,Pcgf5,Igf1r,Ikbke,Klhl25,Dse,Arid5a,Itpr1,Spsb1,Ifit2,Bcl2l11,Rnf114,Gypc,Ggct,Tnfsf8,Usp18,Crim1,Atp11b,Traf5,Rras2,Pfkfb3,Pde3b |
| 1.152e-05 | -11.37 | TENEDINI_MEGAKARYOCYTE_MARKERS | MSigDB lists | TENEDINI_MEGAKARYOCYTE_MARKERS | 66 | 17 | 15632 | 1249 |
Il6,Myc,Casp3,Stat3,Pdgfb,Jun,Fos,Ccl5,Ccne1,Stat5a,Jarid2,Pf4,Il1b,Pdgfc,Jak2,Mafg,Stat1 |
| 1.156e-05 | -11.37 | GBP_C | pfam domains | PF02841 | 13 | 7 | 18711 | 1348 |
Gbp7,Gbp9,Gbp4,Gbp2,Gbp2b,Gbp8,Gbp3 |
| 1.168e-05 | -11.36 | MODULE_173 | MSigDB lists | MODULE_173 | 16 | 8 | 15632 | 1249 |
Dusp6,Fpr1,Adora2b,Dusp8,Dusp2,Gadd45g,Dusp4,Rgs3 |
| 1.168e-05 | -11.36 | KOBAYASHI_EGFR_SIGNALING_6HR_DN | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_6HR_DN | 16 | 8 | 15632 | 1249 |
Ier3,Cx3cl1,Jun,Dusp6,Dusp5,Maff,Dusp4,Ccnd1 |
| 1.168e-05 | -11.36 | GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION | 16 | 8 | 15632 | 1249 |
Pml,Zc3h12a,Ptger4,Nlrp3,Mefv,Il10,Tnfaip3,Errfi1 |
| 1.177e-05 | -11.35 | epithelial tube morphogenesis | biological process | GO:0060562 | 359 | 47 | 20694 | 1406 |
Sec24b,Myc,Kdm5b,Prkx,Mmp14,Sema4c,Tmem67,Edn1,Clic4,Csf1,Spry2,Notch2,Angpt1,Met,Acvrl1,Apaf1,Ift57,Sdc4,Acvr1,Pml,Casp8,Tnc,Kdr,Cited2,Phactr4,Tulp3,Fzd1,Mthfd1l,Hmga2,Hhex,Notch1,Spint2,Gja1,Ptch1,Lmo4,Casp3,Ahr,Pbx1,Src,Nr3c1,Timeless,Lhx2,Bmp2,Hif1a,Mthfr,Flt1,Vasp |
| 1.198e-05 | -11.33 | NAD+ ADP-ribosyltransferase activity | molecular function | GO:0003950 | 23 | 9 | 20217 | 1400 |
Parp8,Zc3hav1,Parp10,Parp9,Tiparp,Parp14,Parp11,Parp3,Parp12 |
| 1.218e-05 | -11.32 | GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | MSigDB lists | GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 660 | 84 | 15632 | 1249 |
Arid5b,Ptprj,Vegfc,Pilrb1,Gcnt2,Plat,Bambi,Lcp2,Flrt2,Atp6v1d,Sipa1l1,Pdgfrb,Nampt,Gdf15,Inhba,Rapgef2,Tyk2,Hap1,Ddit4,Nrp2,Caml,Pdgfb,F11r,Fgr,Lif,Pml,Csrnp1,Pdgfc,Crim1,Hck,Mvp,Bmp2,Rgs14,Stat5a,Axl,Src,Lrp4,Acvr1,Acvrl1,Fut8,Casp3,Stat3,Rhoq,Acvr1b,Lyn,Adrb2,Ptk2,Mmp9,Igf1r,Socs7,Jak2,Actb,Arf4,Polr2g,Kdr,Ltbp2,Lnpep,Met,Csf1,Phip,Ppm1l,Irs2,Cdk5r1,Nck1,Mapkapk2,Egr1,Spred1,Angpt1,Pilrb2,Pilra,Cyfip1,Fos,Zyx,Cited2,Ptpn2,Jun,Tiparp,Flt1,Itgav,Flrt3,Syk,Ccl12,Sdc2,Stap1 |
| 1.221e-05 | -11.31 | GSE6092_CTRL_VS_BORRELIA_BIRGDOFERI_INF_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE6092_CTRL_VS_BORRELIA_BIRGDOFERI_INF_ENDOTHELIAL_CELL_DN | 131 | 26 | 15632 | 1249 |
Mafg,Gng4,Kdm6b,Plaur,Plk2,Cd274,Gch1,Arl5b,Isg20,Gpr132,Irs2,Isg15,Nxf1,Etv3,Atf3,Tnfaip3,F10,Ets2,Arid5a,Sqstm1,Gadd45b,Nfkbia,Dusp4,Psd,Nfkbie,Mafk |
| 1.228e-05 | -11.31 | generation of neurons | biological process | GO:0048699 | 1664 | 157 | 20694 | 1406 |
Igf1r,Psd,Mosmo,Nlgn2,Mycl,Tmem67,Vcam1,Ext1,Kat2b,Uchl1,Zhx2,Rab10,Ccl5,Bcl6,Sec24b,Ednrb,Actb,Slc4a7,C3,Mark2,Agrn,Rnd1,Stxbp1,Egr2,Kdr,Fzd1,Tcf4,Sod2,P2ry12,Jun,P2ry2,Cx3cl1,Zswim4,Tnf,Prdm1,Nck1,Met,Ikzf1,Sdc4,Fcgr2b,Katna1,Etv5,Dbnl,Gja1,Lmo4,Itpr1,Ptch1,Casp3,Kremen1,Klf7,Cav1,Lyn,Nr4a3,Clcf1,Spire1,Cdk5r1,Pbx1,Arf4,Btg2,Mdm2,Palld,Sirt1,Axl,Fubp1,Il15ra,Hmga2,Ppp2r3a,Il1b,Kdm4a,Il6,Cyfip1,Hif1a,Casz1,Ier2,Cflar,Vasp,Mmd,Mturn,Phgdh,Jag1,Nrp2,Cd38,Lhx2,Rapgef2,Plk2,Sema4a,Bmp2,Ifrd1,D16Ertd472e,Spen,Sema4c,Tsku,Ntng2,Triobp,Sipa1l1,Stap1,Flrt2,Igsf9,Fas,Csf1,Lrp8,Myc,Itga4,Ptk2,Dync1i2,Prag1,Clic5,Zeb1,Rac3,Vegfc,Tulp3,Mov10,Mecp2,Kif3c,Tnc,Kif5c,Ehd1,Tspo,Adora2a,Ust,Evl,Hdac1,Rab21,Cnp,Cx3cr1,Ddit4,Sdc2,Crkl,Rap1gap2,Sphk1,Jak2,Flrt3,Inhba,Tlr2,Tnfrsf1b,Gfi1,Rgs14,Notch1,Scarf1,Lif,Pdgfb,Dst,Scn1b,Lrp4,Lpar1,Mul1,Nr3c1,Sema3c,Map4k4,Stat3,Lst1,Micall2,Hap1,Map2k1,Dock10,Eif4g2,Ldlr |
| 1.229e-05 | -11.31 | ODONNELL_TFRC_TARGETS_UP | MSigDB lists | ODONNELL_TFRC_TARGETS_UP | 344 | 51 | 15632 | 1249 |
Rgs1,Fam20c,Cdkn1a,Il13ra1,Ep400,Cd69,C1rl,Rbm43,Zbp1,Tnfrsf14,Fas,Nek6,Il4ra,Tor1aip2,Tmem171,Ifrd1,Kremen1,Tra2a,Cx3cr1,Gadd45b,Sqstm1,Ass1,Cited2,Jun,Thbs1,Dcbld2,H2-Ab1,Slamf8,Pim1,Map3k8,Ptafr,Gpr85,Nr4a3,Wdr59,H2-Aa,Dgka,Pde4b,Junb,Gch1,Ppp1r15a,Plk2,Lcp2,Ube2f,Mxd1,Csrnp1,F11r,Casp3,Sat1,Cp,Klf6,Dusp1 |
| 1.231e-05 | -11.31 | regulation of tumor necrosis factor biosynthetic process | biological process | GO:0042534 | 29 | 10 | 20694 | 1406 |
Errfi1,Jak2,Spn,Thbs1,Tlr2,Tlr1,Tnfrsf8,Mapkapk2,Il10,Cx3cr1 |
| 1.231e-05 | -11.31 | CD4-positive, alpha-beta T cell differentiation involved in immune response | biological process | GO:0002294 | 29 | 10 | 20694 | 1406 |
Il6,Spn,Ptger4,Gadd45g,Irf4,Batf,Stat3,Sema4a,Relb,Il12b |
| 1.231e-05 | -11.31 | T-helper cell differentiation | biological process | GO:0042093 | 29 | 10 | 20694 | 1406 |
Relb,Sema4a,Il12b,Il6,Gadd45g,Ptger4,Spn,Irf4,Batf,Stat3 |
| 1.237e-05 | -11.30 | PAX_Q6 | MSigDB lists | PAX_Q6 | 229 | 38 | 15632 | 1249 |
Tnfsf10,Stip1,Mob3c,Rcl1,Egr3,Ppa1,Trib1,Gpr85,Clec4d,Ier3,Nrp2,Inhba,Jag1,Leng9,Etv6,Myadm,Cd274,Layn,Lmo4,Batf,Rnf34,Gnb4,Etv5,Rgs3,Tnks1bp1,Tle3,Atf3,Prdm1,Hhex,Prrg4,Icam1,Cd74,Slco3a1,Spry2,Cp,S1pr2,P4ha2,Dock4 |
| 1.237e-05 | -11.30 | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_UP | MSigDB lists | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_UP | 187 | 33 | 15632 | 1249 |
Jarid2,Rgl1,Birc3,Pdgfrb,Slpi,H2-Aa,Fzd1,Hp,Rtn1,Il13ra1,Hmox1,Dnajb4,Ptafr,Il18,Ier3,Vcam1,Il1b,Abcc1,Ets2,Il4i1,Cp,Slc44a1,Vcan,Mid1,Tmem176b,Prdm1,Usp25,Ccl22,Prnp,Fgr,F10,Cd14,Klf7 |
| 1.255e-05 | -11.29 | positive regulation of smooth muscle cell migration | biological process | GO:0014911 | 62 | 15 | 20694 | 1406 |
Pdgfb,Ptger4,Lpar1,Nr4a3,P2ry2,Dock4,Ccl5,Egr1,Myc,Mdm2,Il18,Plau,Src,Pdgfrb,Ptk2 |
| 1.260e-05 | -11.28 | FoxO signaling pathway | KEGG pathways | mmu04068 | 132 | 28 | 7931 | 713 |
Gadd45b,Ccnd2,Atm,Sgk3,Bcl6,Akt3,Tnfsf10,Il10,Pik3cd,Irs2,Klf2,Ccng2,Bcl2l11,Bnip3,Stat3,Plk2,Homer1,Sirt1,Cdkn2d,Mdm2,Igf1r,Map2k1,Cdkn1a,Sod2,Plk3,Ccnd1,Il6,Gadd45g |
| 1.264e-05 | -11.28 | GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 94 | 21 | 15632 | 1249 |
Casp3,Inhba,Casp2,Bcl2a1d,Tnf,Itgav,Bcl2l11,Tnfrsf1b,Bcl2a1b,Traf2,Casp8,Bcl2a1a,Jak2,Kitl,Daxx,Il1b,Fas,Tlr3,Pml,Il1a,Acvr1b |
| 1.266e-05 | -11.28 | GO_LEUKOCYTE_MEDIATED_IMMUNITY | MSigDB lists | GO_LEUKOCYTE_MEDIATED_IMMUNITY | 139 | 27 | 15632 | 1249 |
Swap70,Dennd1b,Il6,Ctsc,C1ra,Fas,Il4ra,Icam1,Cd74,Slamf7,Batf,Prdx1,H2-Eb1,Irf7,C1rl,Stxbp3,Rasgrp1,Pou2f2,Jag1,C3,H2-Ab1,Cd55,Nr4a3,Pik3cd,Lyn,Serpinb9,Trem1 |
| 1.269e-05 | -11.27 | GSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN | MSigDB lists | GSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN | 179 | 32 | 15632 | 1249 |
Plk2,Tnfsf14,Dcp1a,G3bp2,Socs3,Casp7,Hmgcs1,Rnf19b,Endod1,Adrb2,Rgs1,Dr1,Cmklr1,Bcl2a1a,Bcl2a1b,Tnf,Nr4a1,Zyx,Rhbdf2,Timp1,Peli1,Gclm,Nr3c1,Bcl2a1d,Dock10,Jmjd6,Prnp,Gpc1,Lipg,Pfkfb3,Me1,Stau1 |
| 1.269e-05 | -11.27 | GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_UP | 179 | 32 | 15632 | 1249 |
Fgr,Hhex,Cd14,Sav1,Tcf4,Tspan3,Psmd10,Swap70,Cox17,Slc15a3,Rhoq,Irf4,Fcgr2b,Map3k8,Trib3,Trib1,Oas1g,Cd200,Snn,Cdkn1a,Irf7,Cnp,Irf8,Tor3a,S100a8,Plek,Rabgef1,Hk2,Pde7b,Oas1a,Ampd3,Isg20 |
| 1.269e-05 | -11.27 | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN | MSigDB lists | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN | 179 | 32 | 15632 | 1249 |
Zc3hav1,Ddx58,Usp18,Ifih1,Slc30a1,Ddx60,Cnot4,Acvr1,Optn,Cpd,Rsad2,Bcl2a1d,Spry2,Abcb1a,Fut8,Arid5a,D16Ertd472e,Rhof,Gadd45b,Ifit1bl1,Ifnar1,Bcl2a1b,Abcc4,Htr2b,Bcl2a1a,Mtmr14,Slc31a1,Tdrd7,Tlr1,Casp4,Dach1,Ifit1bl2 |
| 1.269e-05 | -11.27 | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_UP | MSigDB lists | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_UP | 179 | 32 | 15632 | 1249 |
Ptgir,Dyrk2,Egr3,Cdc42ep4,Frmd4a,Ifit3b,Cacna1d,Frmd6,Pmepa1,Igf2bp2,4930523C07Rik,Golga3,Ifit3,Ampd3,Bcl9,Nfkbid,Trim56,Sell,Calcrl,Zfp281,Zbp1,Sgk3,Rab3ip,Ptpn2,Tiparp,Gpr18,Ubtd2,Acvrl1,Cers6,4932438A13Rik,Lztfl1,Treml2 |
| 1.269e-05 | -11.27 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP | 179 | 32 | 15632 | 1249 |
Stau1,Trim13,Bcl2a1d,Gpr68,Vcan,Kremen1,Pnp2,Arhgef3,Bcl2a1b,Flt1,Plaur,Bcl2a1a,Vcam1,Mafg,Ptgs2,Chic2,Trib3,Acvr1b,Clec5a,St3gal1,Hk2,Met,Stx6,Fzd1,Bst1,Med13,Htra1,Trim21,Pid1,Tor1aip1,Card6,Dusp6 |
| 1.272e-05 | -11.27 | T cell mediated immunity | biological process | GO:0002456 | 48 | 13 | 20694 | 1406 |
Ctsc,Serpinb9b,Il12b,Stx11,Il18rap,H60b,Il18,Treml4,Serpinb9,Dennd1b,Icam1,Jag1,Raet1e |
| 1.288e-05 | -11.26 | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP | MSigDB lists | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP | 87 | 20 | 15632 | 1249 |
Gadd45g,Cebpd,Zfp36,Btg2,Ddit4,Bcl6,Serpine1,Tiparp,Jun,Klf2,Nfkbia,Gadd45b,Nfil3,Cdkn1a,Rras2,Rnd3,Cdc42ep4,Irs2,Mthfd2,Atf3 |
| 1.303e-05 | -11.25 | regulation of cellular response to oxidative stress | biological process | GO:1900407 | 85 | 18 | 20694 | 1406 |
Met,Sirt1,Hk3,Hsph1,Txn1,Gch1,Glrx,Il10,Tlr6,Nox1,Hif1a,Fut8,Tnf,Nr4a3,Sod2,Ncoa7,Slc7a11,Fzd1 |
| 1.305e-05 | -11.25 | regulation of JNK cascade | biological process | GO:0046328 | 190 | 30 | 20694 | 1406 |
Tnf,Mapkbp1,Mdfic,Il1a,Ripk2,Mul1,Traf2,Syk,Rasgrp1,Map2k4,Fcgr2b,Myd88,Phlpp1,Map4k4,Tlr9,Nod2,Nod1,Nox1,Tlr6,Edn1,Igf1r,Tlr3,Dnaja1,Il1b,Il1rn,Gadd45b,Fzd5,Mlkl,Aida,Gadd45g |
| 1.306e-05 | -11.25 | GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_DN | MSigDB lists | GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_DN | 155 | 29 | 15632 | 1249 |
Cd69,Vasp,Dgka,Tlr1,Ext1,Cnp,Dusp6,Sesn3,Ccne1,Mthfd1l,Wdr43,Ikbke,Rcsd1,Filip1l,Cd55,Treml2,Tnfsf8,Fchsd2,Peli1,Myc,Mdn1,Usp53,Plac8,Rab3ip,Rras2,Rtp4,Etv3,Rhoh,Evl |
| 1.306e-05 | -11.25 | GSE22886_NEUTROPHIL_VS_DC_UP | MSigDB lists | GSE22886_NEUTROPHIL_VS_DC_UP | 155 | 29 | 15632 | 1249 |
Zeb1,Bcorl1,Isg20,Hopx,Klf2,Pdk3,Fcgr4,Pde4b,Trem1,Bambi,Tnfsf10,Gca,Fpr1,Ddx4,Mefv,Mppe1,Ptgs2,Pim2,Oasl1,Xkr8,Cebpd,Rsad2,Treml2,Gpsm2,Csf3r,Insl6,Dusp1,Clec4e,Sell |
| 1.306e-05 | -11.25 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_DN | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_DN | 155 | 29 | 15632 | 1249 |
Med13,Btg2,Il18rap,Pde4b,Rabgef1,Adap2,Tnfsf14,Ccl4,Bcl2a1a,Agpat4,Itpkc,Zc3h12a,Arid5b,Nr4a3,Fcho2,Egr2,Il4i1,Dusp2,Bcl2a1d,Il18bp,Bcl2a1b,Klf3,Parp8,Fos,Homer1,Sgk3,Vcpip1,Mpp7,Cyth3 |
| 1.311e-05 | -11.24 | HELLER_HDAC_TARGETS_UP | MSigDB lists | HELLER_HDAC_TARGETS_UP | 273 | 43 | 15632 | 1249 |
Cpd,Hspa2,4932438A13Rik,Kdm5b,Micall2,Sat1,Bcl6,Gpsm2,Agrn,Slc16a3,Ifit1bl1,Cenpe,Mark2,Cd80,Sgk3,Sdc4,Isg15,Pigv,Arg2,Cdkn2d,Mapkapk2,Marcksl1,Tyk2,Pdlim7,Rtn2,Slc9a1,Tmeff1,Plk2,Klf2,Ifit1bl2,Birc3,Junb,Prkar2b,Cdkn1a,H3f3b,Idi1,Fam20c,Fscn1,Pik3cd,Cxcl10,Stat1,Il13ra1,Ptger4 |
| 1.332e-05 | -11.23 | MODULE_19 | MSigDB lists | MODULE_19 | 282 | 44 | 15632 | 1249 |
Abcb1a,Vcan,Nqo1,Gadd45g,Nr4a1,Ifit1bl1,Ccl12,Tspan3,Fos,Cited2,Cd34,Ccnd2,Gbe1,Cdk5r1,Papss2,Cnn3,Alas1,St3gal5,Tnfaip2,Hcls1,Ldlr,Ccnd1,Rbpms,Itpr1,Mtus1,Bcl6,Birc2,Pbx1,Cd14,Plk3,Nfkbil1,Nupr1,Ddit4,Junb,Ifit1bl2,Gja1,Ppp1r15a,Pdgfrb,Fosb,Bambi,Gng12,Glrx,Cd55,Phyh |
| 1.342e-05 | -11.22 | SRF_Q4 | MSigDB lists | SRF_Q4 | 196 | 34 | 15632 | 1249 |
Ier2,Abr,Mapkapk2,Zfp513,Egr1,Cx3cl1,Tle3,Klf6,Nr4a1,Tagln,Fos,Cited2,Tank,Edn1,Egr2,Dusp2,Mmp14,Gadd45g,Mid1,Egr3,Dusp5,Actb,Thbs1,Junb,Csrp1,Dcun1d3,Dusp6,Myo1b,Fosb,Ptch1,Med13,G3bp2,Ppp2r3a,Vasp |
| 1.353e-05 | -11.21 | GO_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | 109 | 23 | 15632 | 1249 |
Tnfsf14,Tnfrsf1b,Psmb8,Birc3,Tnfsf15,Psme2,Psmb6,Stat1,Tnfsf4,Jak2,Cd40,Birc2,Psmd10,Traf2,Psmb9,Tnf,Psma6,Psmb10,Psme1,Fas,Aim2,Tnfrsf14,Tnfrsf8 |
| 1.354e-05 | -11.21 | GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | 327 | 49 | 15632 | 1249 |
Ifi207,Hinfp,Ifi214,Atf3,Egr1,Irf4,Myc,Fos,Ets2,Jun,Nr4a1,Nfil3,Gfi1,Irf1,Ifi204,Pou2f2,Ifi203,Etv6,Ifi211,Plscr1,Mndal,Dach1,Jdp2,Plagl2,Batf,Pbx1,Zfp281,Hif1a,Prdm1,Hhex,Mxd1,Aebp2,Cebpd,Nr3c1,Stat3,Egr2,Batf2,Ifi209,Tcf4,Ifi205,Ifi213,Nfxl1,Nfkb2,Nr4a3,Btg2,Ifi208,Fosb,Irf7,Junb |
| 1.388e-05 | -11.19 | GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | MSigDB lists | GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | 188 | 33 | 15632 | 1249 |
Dusp5,Kdm6b,Hmgcs1,Mafg,Ldlr,Cldnd1,Dnajb2,Pkp4,Gng12,Myadm,Brwd3,Junb,Plek,Pdk3,Lcp2,Cd86,Atxn7l1,Slpi,St3gal5,Gpr132,Tmem176a,Hivep3,Atf3,Tmem176b,Fas,Ier2,Hif1a,Lipg,Spred1,Bcl2l11,Spn,Rab9,Glipr2 |
| 1.388e-05 | -11.19 | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | 188 | 33 | 15632 | 1249 |
Sass6,Gbe1,Icam1,Tpi1,Lrp8,Mcm10,Etv5,Gnb4,Eno1,Itpr1,Slc7a11,Bnip3,Phgdh,Stat3,Cycs,Mthfd2,Ak4,Pim1,Endod1,Fam162a,H3f3b,Stip1,Clic4,Il1rn,Fscn1,Mthfd1l,Eno2,Hsd17b12,Txn1,Hk2,Alas1,Zeb1,Ddit4 |
| 1.388e-05 | -11.19 | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN | 188 | 33 | 15632 | 1249 |
Spred1,Hhex,Mcm10,Egr1,Nmral1,Cyth3,Ubash3b,Rtp4,Tpx2,Casp3,Gbp4,Gbp9,Egr2,Bcl2a1d,Rsad2,Cenpe,Bcl2a1b,Bcl2a1a,Glrx,Gfi1,Sema4c,Pcgf5,Ppa1,Ldha,Rcn1,Gpd2,Serpinb9,Isg20,Hsd17b12,Nampt,Jdp2,Dusp6,Irf8 |
| 1.388e-05 | -11.19 | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_UP | 188 | 33 | 15632 | 1249 |
Ogfrl1,Rai14,Pnp2,Fut8,Stat3,Cyfip1,Cst7,Cnn2,Map3k6,Gys1,Cd34,P2ry14,Mapkapk2,Hhex,Egln3,Car13,Tifa,Plscr1,Myadm,Hsd17b12,Cmpk2,Lrrc8c,Cdkn1a,Nlgn2,Gng12,Cd300lf,Fscn1,Acsl1,Ier3,Clec4d,Fam111a,Uchl1,Rnf19b |
| 1.398e-05 | -11.18 | GNF2_HLA_C | MSigDB lists | GNF2_HLA_C | 54 | 15 | 15632 | 1249 |
Tapbp,Phf11b,H2-Q4,Psd4,H2-Q6,Serp1,Phf11a,Hcls1,Phf11c,Tap1,H2-Q7,Max,Irf1,Phf11d,Psmb10 |
| 1.398e-05 | -11.18 | GO_REGULATION_OF_B_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_B_CELL_PROLIFERATION | 54 | 15 | 15632 | 1249 |
Casp3,Peli1,Bst1,Atm,Il10,Bcl6,Cd40,Clcf1,Cd38,Cdkn1a,Ahr,Prdm1,Cd74,Lyn,Irs2 |
| 1.414e-05 | -11.17 | negative regulation of T cell proliferation | biological process | GO:0042130 | 70 | 16 | 20694 | 1406 |
Tnfrsf14,Tarm1,Slfn1,Cd80,H2-Aa,Casp3,Arg2,Lgals9,Cd86,Cd274,Sdc4,Pde5a,Spn,Prnp,H2-Ab1,Peli1 |
| 1.418e-05 | -11.16 | double-stranded RNA binding | molecular function | GO:0003725 | 84 | 18 | 20217 | 1400 |
Ddx60,Oasl1,Ago3,Hspa1a,Oas2,Ddx58,Oas1a,Tlr3,Stau1,Oas3,Oas1g,Mtdh,Eif2ak2,Ifih1,Oasl2,Oas1b,Adar,Dhx58 |
| 1.427e-05 | -11.16 | GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP | MSigDB lists | GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP | 180 | 32 | 15632 | 1249 |
Pid1,Lad1,Fubp1,Nampt,Birc3,Dusp6,Map4k4,Ikbkg,Tbc1d13,Spen,Isg20,Pdlim7,Fpr1,Filip1l,Trem1,Thbs1,Hcls1,Cldnd1,Fos,Slc25a37,Src,Plac8,Cst7,Casp1,Slc7a11,Txnrd1,Pnp2,Traf1,St3gal6,Lrp8,Olr1,Gng11 |
| 1.427e-05 | -11.16 | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_DN | 180 | 32 | 15632 | 1249 |
Ccl4,Cldnd1,Plaur,Abcc1,Pmepa1,St3gal1,Mmp9,Map2k4,St3gal5,Pla2g7,Spint2,Myadm,Rnf14,Myo1b,Sco1,Gna15,Osm,Traf5,Sav1,Ube2f,Ahr,Stxbp1,Psmb10,Irf4,Gclm,Rnf24,Il18bp,Mafk,Fgl2,Sdc2,Rgs14,Zyx |
| 1.427e-05 | -11.16 | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP | MSigDB lists | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP | 180 | 32 | 15632 | 1249 |
Tmem229b,Ms4a6d,Filip1l,Endod1,Gfi1,Epsti1,Tnfsf10,Vcam1,Sipa1l1,Cd86,Sesn3,Mmd,Ext1,Rnf135,Ifih1,Cyth3,Itga4,Zfp319,Sla,Fos,Ddhd1,Plac8,Gpr68,Samd9l,Prdx5,Lztfl1,Chst11,Dbnl,Slc39a4,Ppp2r5a,Abcb1a,1110038F14Rik |
| 1.427e-05 | -11.16 | GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_UP | 180 | 32 | 15632 | 1249 |
Kdm5b,Ccdc86,Tnfsf8,Klf6,Psip1,Tagln,Gda,Atp11b,Rbms2,Pfkfb3,Coa5,Sdc1,Nxf1,Mcm10,Hlx,Kctd12,Zc3h7a,Akt3,Ubr4,Plekha2,Rgl1,S100a8,Dio2,Ap3m2,Pmepa1,Sec24b,Rbms1,Gca,Pim1,Ddx4,Smox,Smc5 |
| 1.427e-05 | -11.16 | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | 180 | 32 | 15632 | 1249 |
Crlf3,Adar,Rab3ip,Gbp2,Psme1,Evl,Slc30a4,Tlr6,Sell,Il4ra,Psmb10,Nat2,Peli1,Spsb1,Srm,Abcc5,Ets2,Birc2,Znrf1,Ldlr,Ikbke,Rnaset2b,Plaur,Dnajb2,Nr4a3,Ext1,Timeless,Ampd3,Dgka,P4ha1,Rnaset2a,Lmo4 |
| 1.427e-05 | -11.16 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_DN | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_DN | 180 | 32 | 15632 | 1249 |
Prnp,Usp18,Sgms2,Rtp4,Rhoh,Ifit1,Tle3,Vcpip1,Cd83,Arid5a,Nr4a1,Kdm5b,Rsad2,Irgm2,Tnc,Ifi44,Aftph,Acvr1b,Mppe1,Tlr3,Endod1,Stat1,Oasl1,Rcl1,Tnip1,Mov10,Cnp,Jdp2,Ahrr,Rab10,Tlr1,Slpi |
| 1.441e-05 | -11.15 | drug binding | molecular function | GO:0008144 | 1638 | 157 | 20217 | 1400 |
Plk3,Prag1,Smc5,Stk40,Pgk1,Myo1b,Nlrc4,Slfn5,Flt1,Nlrp3,Map4k4,Pdk3,Acvrl1,Nampt,Pfkl,Ddx58,Sphk1,Map3k6,Pim1,Ikbke,Tor3a,Hk2,Map3k8,Nek6,Pcx,Mlkl,Dnaja1,Htr2a,Ube2f,Pnp2,Papss2,Slfn9,Alas1,Hk3,Nos2,Hmgcs1,Map2k1,Hspa1a,Etnk1,Ripk2,Clcn5,Fscn1,Clcn7,Cgas,Myo10,Trib3,Ass1,Tap1,Vrk2,Helz2,Tyk2,Oas2,Atp10a,Nod1,Kdr,Ak4,Irak3,Acvr1,Mthfd1l,Abcc5,Oasl2,Tlk2,Hspa1b,Scyl2,Akt3,Ube2e1,Ube2l6,Ehd1,Irak2,Ascc3,Ciita,Ripk3,Igf1r,P2ry2,Syk,Pdgfrb,Acsl5,Mov10,Mapkapk2,Fam20c,Prkx,Slfn8,Ifih1,Src,Eif2ak2,Hspa2,Mcm6,Gk,Kif9,Acvr1b,Hdc,Mark2,Pim2,Sgk3,Adgb,Kif3c,Dhx58,Swap70,Mcm9,Hck,Atm,Acsl1,Tent2,Pik3cd,Hsph1,Tap2,Dync1h1,Dck,Pgs1,Fgr,Hk1,Axl,Met,Map2k4,Rars,Asns,Jak2,Actb,Srxn1,Nlrc5,Dgka,Katna1,Dnaja2,Sik3,Ep400,Atp13a1,Htr2b,Plk2,Lyn,Prkce,Ube2e2,Abcc1,Atp11a,Nod2,Adrb2,Chd9,Trip13,Oasl1,Abcb1a,Ddx4,Trib1,Gclc,Apaf1,Ptk2,Grk3,Dyrk2,Wars,Pim3,Atp2b4,Tent4a,Ksr1,Oas3,Itpkc,Pikfyve,Cenpe,Cmpk2,Sod2 |
| 1.442e-05 | -11.15 | GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT3_PROTEIN | MSigDB lists | GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT3_PROTEIN | 42 | 13 | 15632 | 1249 |
Lif,Socs3,Ptger4,Il12b,Socs1,Il18,Il15,Clcf1,Jak2,Osm,Ptpn2,Il6,Stat3 |
| 1.442e-05 | -11.15 | GO_TUMOR_NECROSIS_FACTOR_RECEPTOR_SUPERFAMILY_BINDING | MSigDB lists | GO_TUMOR_NECROSIS_FACTOR_RECEPTOR_SUPERFAMILY_BINDING | 42 | 13 | 15632 | 1249 |
Casp3,Tnfsf8,Tnfsf15,Traf2,Tnfsf14,Casp8,Tnf,Myd88,Cflar,Tnfsf10,Traf1,Tnfsf4,Stat1 |
| 1.442e-05 | -11.15 | STREICHER_LSM1_TARGETS_UP | MSigDB lists | STREICHER_LSM1_TARGETS_UP | 42 | 13 | 15632 | 1249 |
Kdm5b,Il6,Pdgfb,Cited2,Bcl6,Daam1,Arid4a,Rbl1,Il15ra,Tnfsf10,Pbx1,Stat2,Il13ra1 |
| 1.442e-05 | -11.15 | ABBUD_LIF_SIGNALING_1_UP | MSigDB lists | ABBUD_LIF_SIGNALING_1_UP | 42 | 13 | 15632 | 1249 |
Irf1,Upp1,St3gal1,Tmem176b,Socs3,Lcn2,Psmb8,Cxcl14,Rhou,Tapbp,Tmem176a,Stat3,Nmi |
| 1.451e-05 | -11.14 | GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 140 | 27 | 15632 | 1249 |
Pde5a,Ifit1bl1,Parp8,Fam43a,Msr1,Bcl6,Cd302,Clec4e,Hk3,Il1a,Spata13,Slc9a1,Srxn1,Ampd3,Jag1,Ifit1bl2,Klf2,Irf7,Osbpl3,Slc29a3,Tmem219,Tnfsf4,Mmp9,Itga5,Zc3h12a,Frmd4a,Sema4a |
| 1.456e-05 | -11.14 | SH2 | interpro domains | IPR000980 | 105 | 21 | 19984 | 1430 |
Socs1,Stat2,Cish,Stat1,Lcp2,Socs3,Stat3,Syk,Sla,Rin2,Src,Nck1,Hck,Crkl,Lyn,Fgr,Stat4,Stat5a,Jak2,Stap1,Socs7 |
| 1.458e-05 | -11.14 | GSE17721_POLYIC_VS_CPG_6H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_6H_BMDC_DN | 172 | 31 | 15632 | 1249 |
Olr1,Gpc1,Rras2,F10,Nlrp3,Tlr6,Pgs1,Magohb,Marcksl1,Sele,Vcan,Chst11,Ccl2,Cd302,Ets2,Clmp,Gadd45b,Aoah,Wdr43,Abcc1,Nfkb2,Thbs1,Slfn3,Gpd2,Clec4d,Traf3ip2,Hmgcs1,Ptger4,Phlda1,Btg2,Slfn4 |
| 1.458e-05 | -11.14 | GSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN | MSigDB lists | GSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN | 172 | 31 | 15632 | 1249 |
Sap30,Trim14,Gbgt1,Fcgr4,Rgl1,Tshz1,Samsn1,Plekha2,Adap2,Cmklr1,Lacc1,Etnk1,Filip1l,Itpkc,Fcho2,Tlr2,Arid5b,Prkce,Myc,Peli1,Arhgap26,Cebpd,Stat5a,Pik3r5,P2ry12,Aff1,Spred1,Etv5,Mxd1,Cd180,Dtx3l |
| 1.459e-05 | -11.13 | REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE | MSigDB lists | REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE | 48 | 14 | 15632 | 1249 |
Irak2,Ppp2r1b,Nod1,Ripk2,Mapkapk2,Map2k4,Tab2,Dusp4,Nod2,Dusp6,Ikbkg,Map2k1,Jun,Fos |
| 1.459e-05 | -11.13 | PID_CERAMIDE_PATHWAY | MSigDB lists | PID_CERAMIDE_PATHWAY | 48 | 14 | 15632 | 1249 |
Map2k4,Nsmaf,Cycs,Ksr1,Myc,Traf2,Map2k1,Casp8,Tnf,Birc3,Nfkbia,Eif2ak2,Nfkb1,Map4k4 |
| 1.476e-05 | -11.12 | actin filament-based process | biological process | GO:0030029 | 536 | 63 | 20694 | 1406 |
Pdgfb,Scn1b,Marcks,Abr,Cflar,Vasp,Syne2,Tmod3,Cnn2,Casp4,Myo1b,Plek,Cdc42ep2,Src,Whamm,Micall2,Kcnj2,Tpm4,Hcls1,Flnb,Dbnl,Rhof,F11r,Rictor,Spire1,Rnd3,Csrp1,Palld,Swap70,Sele,Cnn3,Trip10,Diaph2,Rhoh,Phactr4,Arhgap26,Cacna1d,Pdpn,Tnf,Rhou,Evl,Pstpip2,Fmnl2,Nck1,Ezr,Zyx,Daam1,S1pr2,Antxr1,Rhoq,Triobp,Sipa1l1,Frmd6,Carmil1,Tmsb10,Bcl6,Fscn1,Pdlim7,Pdgfrb,Actb,Rhoc,Rnd1,Rac3 |
| 1.477e-05 | -11.12 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_DN | 164 | 30 | 15632 | 1249 |
Gnb4,Batf,Lpcat2,Atp2b4,Irak3,Itga4,Atf3,Malt1,Tmtc2,Irs2,Nr3c1,Rai14,Stap1,Klf6,Ezr,Tnf,Trim36,Itgav,Sqstm1,Gfi1,Cdkn1a,Hmgcs1,Ebi3,Mmp9,Slc43a3,Pim1,Nr4a3,Syne2,Rasgrp1,Rabgef1 |
| 1.477e-05 | -11.12 | GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 164 | 30 | 15632 | 1249 |
Pnp2,Cish,Gpr68,Itgav,Ezr,Ehd1,Dnaja1,Tnfrsf8,Htr2a,Ripk3,Atp2b4,Stxbp1,Plk3,Arl4a,Ccnd2,Tmtc2,Arl5b,Cysltr2,Gpr132,Syne2,Il12rb1,Dusp6,Plek,Vps54,Hcls1,Idi1,Irak2,Tmod3,Rab20,Odc1 |
| 1.478e-05 | -11.12 | cytoplasmic pattern recognition receptor signaling pathway | biological process | GO:0002753 | 14 | 7 | 20694 | 1406 |
Ripk2,Tifa,Ifih1,Irgm2,Nfkbia,Nod2,Ddx58 |
| 1.503e-05 | -11.11 | GO_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | MSigDB lists | GO_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 95 | 21 | 15632 | 1249 |
Nod1,Irak2,Daxx,Mdfic,Crkl,Ptger4,Mapkapk2,Ripk2,Adora2b,Tab2,Trib1,Map3k8,Map2k4,Mul1,Dbnl,Nod2,Tnf,Map3k6,Nfkb1,Ikbkg,Syk |
| 1.507e-05 | -11.10 | regulation of lipid storage | biological process | GO:0010883 | 42 | 12 | 20694 | 1406 |
Sirt1,Ptpn2,Zc3h12a,Nfkbia,Ttc39b,Nr1h3,C3,Hilpda,Msr1,Itgav,Ikbke,Ehd1 |
| 1.509e-05 | -11.10 | endothelial cell differentiation | biological process | GO:0045446 | 78 | 17 | 20694 | 1406 |
Col18a1,Icam1,Pdpn,Myadm,Clic4,Kdr,F11r,Ezr,Notch1,Rap2c,Kdm6b,Acvr1,Rapgef2,Plod3,Myd88,Met,Acvrl1 |
| 1.516e-05 | -11.10 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | 74 | 18 | 15632 | 1249 |
Dach1,Dhrs9,Sema3c,P2ry12,Pla2g4a,D1Ertd622e,Edn1,Itgb8,Stat4,Ifnb1,Cd69,Calcrl,Kmo,Dmxl2,Il18,Crim1,Spred1,Frmd6 |
| 1.516e-05 | -11.10 | LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP | MSigDB lists | LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP | 74 | 18 | 15632 | 1249 |
Plod2,Bcl2a1b,Sod2,Bcl2a1d,Pla2g4a,Il6,Myc,Adora2b,Prnp,Upp1,Plagl1,Icam1,Hmox1,Igf2bp2,Lrrc8c,Bcl2a1a,Col27a1,Bmp2 |
| 1.530e-05 | -11.09 | CASPASE_HIS | prosite domains | PS01121 | 9 | 6 | 13278 | 1037 |
Casp7,Casp2,Casp4,Casp1,Casp3,Casp8 |
| 1.533e-05 | -11.09 | regulation of response to oxidative stress | biological process | GO:1902882 | 94 | 19 | 20694 | 1406 |
Il10,Glrx,Gch1,Txn1,Hsph1,Hk3,Met,Sirt1,Slc7a11,Fzd1,Ncoa7,Sesn3,Sod2,Nr4a3,Tnf,Fut8,Hif1a,Nox1,Tlr6 |
| 1.536e-05 | -11.08 | GO_DETECTION_OF_BIOTIC_STIMULUS | MSigDB lists | GO_DETECTION_OF_BIOTIC_STIMULUS | 31 | 11 | 15632 | 1249 |
Tlr6,H2-Eb1,H2-Q4,H2-Q7,Nlrp3,Tlr2,Nlrc4,H2-Q6,Tlr1,Nod1,Nod2 |
| 1.544e-05 | -11.08 | GNF2_HCK | MSigDB lists | GNF2_HCK | 88 | 20 | 15632 | 1249 |
Hck,Hk3,Trem1,Cd14,Tnfaip2,Tnfsf10,Pilra,Fpr1,Tlr2,Fgr,Ms4a6d,Stx11,Fgl2,Nod2,Bst1,Igsf6,Cd302,Tnfrsf1b,Casp1,Ccr1 |
| 1.550e-05 | -11.07 | regulation of protein binding | biological process | GO:0043393 | 240 | 35 | 20694 | 1406 |
Mecp2,Ubash3b,Slpi,Pdgfb,Bambi,Traf2,Ripk2,Ifit2,Hopx,Lox,Plk2,Rapgef2,Adrb2,Plscr1,Src,Mitd1,Met,Angpt1,Csf3,Il10,Bmp2,Pim2,Crbn,Cav1,Dnajb2,Dtx3l,Myc,Itga4,Plcl2,Aida,Actb,Mmp9,Trib3,Mark2,Agrn |
| 1.555e-05 | -11.07 | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | 189 | 33 | 15632 | 1249 |
Gadd45b,Rbbp8,Tiparp,Cish,Irgq,Gadd45g,Sdc2,Papss2,Hif1a,Cd14,Sla,Pde3b,Olr1,Prpf4,Pdgfc,Map4k4,Ltbp2,Psd4,Slc7a8,Jarid2,Slc4a7,Plk2,Pid1,Htra1,Mmd,Socs3,Crkl,Nr4a3,Trib1,Inpp1,Nfil3,Agpat4,Gng12 |
| 1.555e-05 | -11.07 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP | 189 | 33 | 15632 | 1249 |
Sema4c,Mtdh,Egr3,Dusp5,Rcsd1,Serpinb9,Map3k8,Fam111a,Slfn3,Acsl5,Ldlr,Slc4a7,Psmb8,Mcm9,Lcp2,Samsn1,Slfn4,Phlda1,Parp12,Rasgrp1,Plagl1,Pttg1,Traf5,Cd83,Rab3ip,Crim1,Ncoa7,Arhgef3,Itpr1,Tpst1,Casp3,Tnfsf8,Cox17 |
| 1.555e-05 | -11.07 | GSE36078_UNTREATED_VS_AD5_INF_IL1R_KO_MOUSE_LUNG_DC_UP | MSigDB lists | GSE36078_UNTREATED_VS_AD5_INF_IL1R_KO_MOUSE_LUNG_DC_UP | 189 | 33 | 15632 | 1249 |
Tnf,Hsph1,Gadd45b,Nfkbia,Zswim4,Clmp,Trmt1l,Ttc39c,Dse,Bcl6,Kdm5b,Dhx58,Bcor,Cyth3,Ddx58,1600014C10Rik,Ifit1,Sesn3,Irf7,Wdr59,Zeb1,Ext1,Rnf19a,Xaf1,Egln3,Max,Stat1,Arid5b,Tnip1,Rcl1,Pkp4,Zhx2,Snn |
| 1.555e-05 | -11.07 | WIERENGA_STAT5A_TARGETS_DN | MSigDB lists | WIERENGA_STAT5A_TARGETS_DN | 189 | 33 | 15632 | 1249 |
Ccnd1,Ogfrl1,Arhgef3,Ifi205,Zyx,Ifi209,Ifi213,Notch1,Ifi207,Angpt1,Batf,Cd14,Pbx1,Gng11,Ubash3b,Ifi214,Irs2,Adora2a,Ifi203,Stx11,Pstpip2,Ifi211,Slc9a1,Ifi208,Irf8,Daam1,Mndal,Lcn2,Plek,Sh3bgrl2,Bambi,Ifi204,Ptgir |
| 1.555e-05 | -11.07 | GSE33425_CD161_INT_VS_NEG_CD8_TCELL_UP | MSigDB lists | GSE33425_CD161_INT_VS_NEG_CD8_TCELL_UP | 189 | 33 | 15632 | 1249 |
Kctd12,Rab10,Caml,Plscr1,Snx10,Ccl5,Dusp16,Pgk1,Arf4,Bcl2a1a,Cd82,Phyh,Ttc39b,Hmgcs1,Fgl2,Cox17,Bcl2a1d,Cpd,Peli1,Nat2,Rhoq,Psmb9,Plac8,Bcl2a1b,Bcl2l11,Itgav,Mdfic,Traf5,Crlf3,Cyth3,Ciapin1,Gbe1,Itga4 |
| 1.555e-05 | -11.07 | GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_UP | MSigDB lists | GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_UP | 189 | 33 | 15632 | 1249 |
Casp1,Syk,Sbds,Plac8,Tiparp,Mgat1,Tcf4,Tpst1,Cd40,Cyfip1,Prkce,Rhoq,Mcoln2,Hhex,Gbp3,Sell,Cd74,Kif9,Hck,Myadm,Snx10,Zc3h12c,H2-Aa,Caml,Cnn3,Rab10,Snx2,Tmod3,Ell2,Nr4a3,Lyn,Il18,Tmem123 |
| 1.555e-05 | -11.07 | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_DN | MSigDB lists | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_DN | 189 | 33 | 15632 | 1249 |
Jmjd6,St3gal6,Upp1,Tnfrsf8,Batf,Crim1,Tnfrsf14,Gypc,Srm,Plod3,Sqstm1,Igsf6,Nr3c1,Ggct,Gsr,Nsmaf,Il2rg,Ptafr,Ak4,Il1rn,Keap1,Tfec,Ccr1,Rgl1,Osm,Gem,Fubp1,Golga3,Tnfsf14,Met,Hk2,Ccrl2,Inhba |
| 1.555e-05 | -11.07 | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_UP | 189 | 33 | 15632 | 1249 |
Cacna1d,Vrk2,Ptprj,Mtdh,Smox,Cd200,Mafg,Adrb2,Reps1,Srxn1,Parp12,Psmb8,Ppp1r15a,Irf8,Serpine1,Col4a2,Myd88,Clcn5,Olr1,Slc28a2,Atf3,Cx3cl1,Slc30a1,Gbe1,Phgdh,Cnot4,Mecp2,Lztfl1,Dtnb,Stat5a,Ifit2,Ttc39c,Tiparp |
| 1.567e-05 | -11.06 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | MSigDB lists | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | 21 | 9 | 15632 | 1249 |
Lyn,Irs2,Socs1,Stat5a,Stat1,Socs3,Jak2,Stat3,Cish |
| 1.567e-05 | -11.06 | GO_CELLULAR_RESPONSE_TO_VIRUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_VIRUS | 21 | 9 | 15632 | 1249 |
Ifnb1,Adar,Ikbke,Ifih1,Irf7,Psmb9,Ddx58,Bcl2l11,Zc3h12a |
| 1.567e-05 | -11.06 | OXFORD_RALA_OR_RALB_TARGETS_DN | MSigDB lists | OXFORD_RALA_OR_RALB_TARGETS_DN | 21 | 9 | 15632 | 1249 |
Rnaset2b,Nqo1,Hk2,Fscn1,Rnaset2a,Slc16a3,Agrn,Tmod3,Palld |
| 1.567e-05 | -11.06 | REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX | MSigDB lists | REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX | 21 | 9 | 15632 | 1249 |
Ripk2,Ikbkg,Nfkbia,Tab2,Nfkbib,Nfkb2,Irak2,Nod1,Nod2 |
| 1.567e-05 | -11.06 | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | MSigDB lists | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | 21 | 9 | 15632 | 1249 |
Tle3,Ier3,Fgr,Upp1,Pim1,Flnb,Gypc,St3gal1,Plek |
| 1.585e-05 | -11.05 | myeloid cell homeostasis | biological process | GO:0002262 | 128 | 23 | 20694 | 1406 |
Axl,Bcl6,Pde4b,Ptpn2,Lyn,Jmjd6,Adar,Hmox1,Hcar2,Tcea1,Klf2,Jak2,Casp3,Hcls1,Ampd3,Prdx1,Ikzf1,Ccl2,Bcl2l11,Tmod3,Il6,Cited2,Arid4a |
| 1.604e-05 | -11.04 | GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_DN | MSigDB lists | GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_DN | 181 | 32 | 15632 | 1249 |
Jun,Bcl2a1b,Rsad2,Bcl2a1d,Gadd45g,Nqo1,Cox17,Minpp1,Socs1,Sell,Ier2,Atp2b4,Sla,Myd88,Batf,Rrs1,Gna15,Tuba4a,Spint2,Slc7a5,Phlpp2,Acsl1,Dyrk2,Ell2,Fndc3a,Gfi1,H3f3b,Adam19,Asf1a,Bcl2a1a,Plcl2,Dr1 |
| 1.604e-05 | -11.04 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_UP | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_UP | 181 | 32 | 15632 | 1249 |
Trafd1,Armc8,Agpat4,Idi1,Chd9,Osbpl3,Spata5l1,Ifit3b,Tapbpl,Fam111a,Nr4a3,Egr3,Il18rap,Stx11,Kctd12,Il10,Hopx,Ifit3,Dcun1d3,Myadm,Ahr,Pnpt1,Sdc4,Ddx58,Nck1,Aim2,Gpr68,Rin2,Optn,Homer1,N4bp1,Apobec3 |
| 1.604e-05 | -11.04 | GSE3982_NEUTROPHIL_VS_BCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_BCELL_UP | 181 | 32 | 15632 | 1249 |
Ifit2,H2-Q4,Cst7,Abcc5,Rgs14,H2-Q6,Ets2,Zyx,Casz1,Tnfsf8,Ppp2r5a,H2-Q7,Icam1,Fgr,St3gal6,Cx3cl1,Plau,Pfkfb3,Cdc42ep2,Clec4e,Hk3,Mfap3l,Rel,Tap2,C1rl,Pstpip2,Hk2,Rnf19b,Fam53c,Dtx2,Mmp25,Dcbld2 |
| 1.604e-05 | -11.04 | GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 181 | 32 | 15632 | 1249 |
Ptch1,Jarid2,Dusp6,Csrp1,Inhba,Hk2,Ddit4,Zeb1,Ppp4r2,Phlda1,Odc1,Cacnb3,Irf1,Rnf145,Rcan1,Adora2b,Plaur,Igf2bp2,Vcam1,Cyfip1,Bcl6,Dusp1,Tagln,Sbds,Agrn,Mdm2,Edn1,Evl,Col18a1,Nupr1,Stau1,Olr1 |
| 1.618e-05 | -11.03 | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION | 61 | 16 | 15632 | 1249 |
Tnf,Il6,Tlr1,Nod2,Tlr6,Ripk2,Tlr9,Tlr3,Tnfsf4,Ptafr,Tlr2,Adora2b,Ddx58,Nod1,Myd88,Il1b |
| 1.625e-05 | -11.03 | regulation of mast cell activation | biological process | GO:0033003 | 49 | 13 | 20694 | 1406 |
Stxbp1,Plscr1,Fgr,Cd300lf,Milr1,Syk,Rabgef1,Hmox1,Nectin2,Nr4a3,Lyn,Adora2b,Il4ra |
| 1.626e-05 | -11.03 | negative regulation of leukocyte mediated immunity | biological process | GO:0002704 | 56 | 14 | 20694 | 1406 |
Lgals9,Parp3,Tap1,Fcgr2b,Clec2d,Spn,Bcl6,Abr,Nod2,Ifnb1,Hmox1,Tap2,Serpinb9,Rabgef1 |
| 1.643e-05 | -11.02 | GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP | MSigDB lists | GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP | 173 | 31 | 15632 | 1249 |
Jun,Cenpe,Cpd,Acvr1,Nfkbie,Minpp1,Abcb1a,Nr3c1,Plagl1,Ier2,Atf3,Ahr,Dusp14,Aff1,Myd88,Cd83,Gem,Ifit3,Rel,Lcp2,Kctd12,Rasgrp1,Mmd,Ep400,Stxbp3,Map3k8,Acsl1,Ifit3b,Slc31a1,Dyrk2,Ptk2 |
| 1.643e-05 | -11.02 | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN | MSigDB lists | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN | 173 | 31 | 15632 | 1249 |
Mppe1,Ttc39b,Asb13,Egr3,Socs3,Tagap,Zhx2,Clcf1,Ccl4,Slfn9,Card6,Nfkbid,Il18rap,Ccnd2,Nxf1,Crim1,Otud1,Jun,Bcl6,Parp8,Aoah,Gsdmd,Cnot4,Kdm5b,Mafk,Cdyl2,Fcgr2b,Slfn8,Spry2,Prkce,Cish |
| 1.651e-05 | -11.01 | transcription factor binding | molecular function | GO:0008134 | 707 | 79 | 20217 | 1400 |
Ahr,Junb,Pim1,Nr3c1,Nlrp3,H2-Ab1,Dcp1a,Src,Mier3,Psip1,Nfkbia,Stat1,Stat3,Ets2,Ifi213,Ifi204,Hcls1,Myc,Rbl1,Jun,Dr1,Egr1,Ifi211,Hspa1a,Kat2b,Crkl,Ifrd1,Hdac1,Med13,Nek6,Mafk,Arid5a,Lmo4,Mndal,Mtdh,Dnaja1,Keap1,Pbx1,Ifi209,Cited2,Jarid2,Spen,Cd34,Sirt1,Tle3,Nr4a1,Notch2,Nr1h3,Rnf14,Nr4a3,Bcor,Daxx,Ifi214,Zeb1,Mecp2,Psma6,Actb,Fos,Optn,Taf4b,Lhx2,Ciita,Eya4,Hhex,Tcf4,Ifi205,Mdfic,Nfkbid,Rbbp8,Ifi207,Psmd10,Egr2,Ifi203,Hmga1,Ccnd1,Trib1,Hif1a,Ncoa7,Ifi208 |
| 1.653e-05 | -11.01 | Allograft rejection | KEGG pathways | mmu05330 | 61 | 17 | 7931 | 713 |
H2-Ab1,Fas,Tnf,H2-Eb1,Il12b,H2-T10,H2-Q7,H2-Q6,Cd86,H2-M2,Il10,Cd80,H2-T24,H2-Aa,H2-T22,Cd40,H2-Q4 |
| 1.653e-05 | -11.01 | Allograft rejection | KEGG pathways | ko05330 | 61 | 17 | 7931 | 713 |
H2-T22,Cd40,H2-Q4,Cd86,H2-Q6,H2-M2,H2-Q7,H2-Aa,H2-T24,Il10,Cd80,Fas,H2-Ab1,H2-T10,Tnf,Il12b,H2-Eb1 |
| 1.655e-05 | -11.01 | GENTILE_UV_LOW_DOSE_UP | MSigDB lists | GENTILE_UV_LOW_DOSE_UP | 26 | 10 | 15632 | 1249 |
Gdf15,Ccne1,Smox,Isg15,Plk2,Ccdc86,Btg2,Sat1,Tap1,Cdkn1a |
| 1.655e-05 | -11.01 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | MSigDB lists | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | 26 | 10 | 15632 | 1249 |
Ddx58,Isg15,Ifih1,Rnf135,Nlrc5,Uba7,Tnfaip3,Ube2l6,Ikbke,Tax1bp1 |
| 1.667e-05 | -11.00 | GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | MSigDB lists | GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 258 | 41 | 15632 | 1249 |
Psmd10,Psmb9,Hspa1a,Dnaja1,Birc2,Dusp1,N4bp1,Psma6,Prkce,Peli1,Arrdc4,Mul1,Psmb10,Sphk1,Isg15,Psme1,Malt1,Ube2e1,Parp10,Rnf139,Pml,Egr1,Daxx,Tnfaip3,Angpt1,Fbxo4,Gclc,Tspo,Cav1,Psmb8,Birc3,Dcun1d3,Trim21,Nmi,Psme2,Trib3,Adrb2,Ptk2,Ripk2,Psmb6,Dnajb2 |
| 1.674e-05 | -11.00 | protein ADP-ribosylase activity | molecular function | GO:1990404 | 14 | 7 | 20217 | 1400 |
Parp8,Parp10,Tiparp,Parp14,Parp11,Parp3,Parp12 |
| 1.674e-05 | -11.00 | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | 606 | 78 | 15632 | 1249 |
Gpc1,Slc16a1,Adar,Pim3,Col4a2,Cd34,Ppfibp1,Ppm1l,Slc30a1,Il4ra,Znrf3,Sgms2,Sdc1,Cpd,S1pr2,Ccl12,Tmem184b,Ldlr,Clcn7,Clcf1,Abcc1,Nlgn2,Hsd17b7,Igf1r,Itga5,Sema4c,Endod1,Dram1,Mafg,Adrb2,Acvr1b,Trib1,Flnb,Zfp36,Slc9a1,Csf1,Rap1gap2,Slc39a14,Ltbp2,Tnfrsf1b,P4ha1,Ppp1r15b,Layn,Ptch1,Ahsa1,Plagl2,Lif,Socs1,Slc39a13,Atp11a,Minpp1,Oaf,Atp13a1,Abcc5,Plod3,Axl,P4ha2,Dusp1,Mgat1,Slc2a1,Nfkb2,Thbs1,Ptges,Dcbld2,Atp10a,Slc43a3,Adora2b,Piezo1,Slc7a5,Btg2,Nrp2,Vasn,Gja1,Myadm,Slc4a7,Hsd17b12,Pdgfrb,Igsf8 |
| 1.682e-05 | -10.99 | GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 149 | 28 | 15632 | 1249 |
Ube2l6,Slpi,Tmem176a,Dgka,Klf2,Epsti1,Prkar2b,St3gal1,Spire1,Frmd4a,Mefv,Lyn,Fut8,Pde1b,Treml2,Fgl2,Slc25a37,Rgs14,Msr1,Ciita,Kif9,Sgk3,Pbx1,Rbl1,Samhd1,Rhoh,Tlr6,Sell |
| 1.684e-05 | -10.99 | GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN | MSigDB lists | GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN | 157 | 29 | 15632 | 1249 |
Clec4e,Rnf34,Pgm1,Atp11a,Tmtc2,Plagl1,Pttg1,Kat2b,Rffl,Fchsd2,Cycs,Gpr84,Nfkbie,N4bp1,Irak2,Ell2,Scyl2,Smc5,Tnfsf15,Slc2a6,Ksr1,Pstpip2,Tmeff1,Usp12,P4ha1,Mier3,Snx10,C1rl,Irf8 |
| 1.706e-05 | -10.98 | cellular divalent inorganic cation homeostasis | biological process | GO:0072503 | 483 | 58 | 20694 | 1406 |
Ptger4,Atp2b4,Kdr,Cmklr1,Cacna1d,Cxcl1,Mt2,Cx3cl1,Ccl3,P2ry2,Adrb2,Slc30a1,Gpr35,Ccl2,Cx3cr1,Ccr1,Pml,Cd40,Atp13a1,Edn1,Ccrl2,Cxcl2,Ccl5,Bnip3,Htr2a,Ednrb,Fpr1,Ptgir,Ccr3,Ero1l,1600014C10Rik,Tmem178,Cxcl10,Rmdn3,Lpar1,Gna15,Slc39a13,Mt1,Cd38,Cacnb3,Fpr2,Hap1,Xcr1,Marcksl1,Jak2,Itpr1,Gja1,Slc39a4,Itgav,Htr2b,Cav1,Cxcl3,Gpr18,Prkce,Swap70,Grina,Il1b,Slc39a14 |
| 1.709e-05 | -10.98 | cytokine metabolic process | biological process | GO:0042107 | 19 | 8 | 20694 | 1406 |
Nod1,Tnfsf15,Irf7,Gadd45g,Il18,Myd88,Trem1,Ifnar1 |
| 1.734e-05 | -10.96 | necrotic cell death | biological process | GO:0070265 | 30 | 10 | 20694 | 1406 |
Ripk3,Fas,Tnf,Tmem123,Casp1,Birc3,Birc2,Traf2,Tlr3,Mlkl |
| 1.734e-05 | -10.96 | negative regulation of interleukin-1 production | biological process | GO:0032692 | 30 | 10 | 20694 | 1406 |
Nlrp3,Mefv,Cx3cl1,Pml,Cx3cr1,Tnfaip3,Acp5,Errfi1,Zc3h12a,Ptger4 |
| 1.741e-05 | -10.96 | GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | 190 | 33 | 15632 | 1249 |
Sell,Gmppb,P2ry14,Calcrl,Ubash3b,Cdkn2d,Hlx,Irak3,Rbms2,Srm,Casp1,Hsph1,Rab21,Stat3,Tbc1d1,Azi2,4930453N24Rik,Ppa1,Atp10a,Sec24a,Mitd1,Inpp1,Ppm1k,Daam1,Card6,Snx10,Tmem176a,Dgka,Kctd12,Uba7,Stat4,G3bp2,Usp12 |
| 1.741e-05 | -10.96 | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_UP | MSigDB lists | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_UP | 190 | 33 | 15632 | 1249 |
Cd200r4,Phlpp1,Ccng2,Dhx58,Abcb1a,Itgb8,Rgs14,Swap70,Ifit1bl1,Gsdmd,Rapgef5,Daxx,Crim1,Hvcn1,Sdc4,Nod1,Trp53i11,Ddx58,Ddx60,Rapgef2,Rap1gap2,Xaf1,Ampd3,Irf7,4930523C07Rik,Ifit1bl2,Ccl5,Epsti1,Glrx,Sh3bgrl2,Rsbn1,Prkx,Kcna3 |
| 1.741e-05 | -10.96 | GSE20715_0H_VS_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_48H_OZONE_LUNG_DN | 190 | 33 | 15632 | 1249 |
Dr1,Stip1,Cdkn1a,Socs3,Ppa1,Ldha,Ptgs2,Adora2b,Phlda1,Rhou,Hat1,Pde4b,Psat1,Nampt,Tnfrsf1b,Tshz1,Cacybp,Lcn2,Med21,Batf,Cd14,Ahsa1,Gclc,Ube2f,Gclm,Il6,Errfi1,Hsph1,Spsb1,Map3k6,Trmt1l,Timp1,Dnaja1 |
| 1.749e-05 | -10.95 | SEIKE_LUNG_CANCER_POOR_SURVIVAL | MSigDB lists | SEIKE_LUNG_CANCER_POOR_SURVIVAL | 9 | 6 | 15632 | 1249 |
Il15,Csf1,Il1b,Tnf,Il10,Il1a |
| 1.749e-05 | -10.95 | GO_INFLAMMASOME_COMPLEX | MSigDB lists | GO_INFLAMMASOME_COMPLEX | 9 | 6 | 15632 | 1249 |
Casp4,Nlrp3,Nlrc4,Casp1,Gsdmd,Aim2 |
| 1.749e-05 | -10.95 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_5 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_5 | 9 | 6 | 15632 | 1249 |
Egln3,Fos,Hmgcs1,Nr4a1,Nfkbiz,Ptger4 |
| 1.771e-05 | -10.94 | - | gene3d domains | 1.10.1410.20 | 12 | 7 | 8819 | 755 |
Oas1b,Oas1g,Oas3,Oasl2,Oasl1,Oas1a,Oas2 |
| 1.782e-05 | -10.94 | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY | MSigDB lists | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY | 55 | 15 | 15632 | 1249 |
Rictor,Akt3,Icosl,H2-Aa,Ppp2r5a,Cd86,Cd274,Src,H2-Eb1,Tnfrsf14,Cd80,Ppp2r1b,Trib3,Map3k8,Lyn |
| 1.782e-05 | -10.94 | KEGG_AUTOIMMUNE_THYROID_DISEASE | MSigDB lists | KEGG_AUTOIMMUNE_THYROID_DISEASE | 55 | 15 | 15632 | 1249 |
Ifna5,Ifna6,H2-Aa,H2-Q6,Il10,Cd86,Cd40,H2-Eb1,H2-Q4,Ifna2,Ifna1,Cd80,H2-Q7,H2-Ab1,Fas |
| 1.782e-05 | -10.94 | PID_IL2_1PATHWAY | MSigDB lists | PID_IL2_1PATHWAY | 55 | 15 | 15632 | 1249 |
Socs3,Mapkapk2,Stat1,Il2rg,Irs2,Socs1,Myc,Prkce,Cish,Stat3,Syk,Stat5a,Jun,Map2k1,Fos |
| 1.793e-05 | -10.93 | IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR | 490 | 66 | 15632 | 1249 |
Cep350,Hdc,Plekha2,Irf8,Alas1,Slpi,Tifa,Pstpip2,Met,Il13ra1,Dram1,Map2k4,Ppp2r1b,Prkar2b,Psip1,Rab32,Cx3cr1,Kcnj2,Fcgr2b,Ctsc,Abr,Gbe1,Coa5,Sgms2,Lpcat2,Gpc1,Fcgr1,F10,Slc31a2,Plek,Ccr1,Mthfd1l,Ttc9c,Map2k1,Sipa1l1,Slfn4,Tlr1,Piezo1,Ext1,Sap30,Stx11,Hp,Spire1,Slfn3,Elmod2,5430427O19Rik,Glrx,Gng12,Casp1,Plekhf2,Abcc5,Mtus1,Sat1,Minpp1,Cers6,Gsr,Dock10,Fgl2,Sell,Sphk1,Ccdc88b,Sav1,Sgk3,Hck,Gda,Hvcn1 |
| 1.797e-05 | -10.93 | Ig-like_dom | interpro domains | IPR007110 | 460 | 58 | 19984 | 1430 |
Clmp,H2-T24,H2-T22,B430306N03Rik,Slamf9,Fcgr4,F11r,Fcgr1,Fcgr2b,Palld,Tarm1,Sema3c,Cd200r4,Igsf9,Nectin4,H2-M2,Kdr,Il18rap,Tapbp,Malt1,Cd86,Axl,Trem1,Cd80,H2-Q6,H2-Q7,A530064D06Rik,Cd200,H2-Eb1,H2-Ab1,Cd274,Pvr,Slamf7,Cd83,Vcam1,Il18bp,H2-Aa,Mfap3l,Vcan,Treml2,Milr1,Igsf8,Spaca6,Nectin2,Pdgfrb,Siglece,Sema4c,H2-T10,Igsf6,Gm5150,Flt1,Icosl,Slamf8,Treml4,Tapbpl,H2-Q4,Il12b,Icam1 |
| 1.800e-05 | -10.93 | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | 182 | 32 | 15632 | 1249 |
Ifi209,Ifi205,Otud1,Tagln,Ifi213,Dusp1,Samd9l,Ccng2,Cebpd,Optn,Kdm5b,Abcb1a,Ifi214,Ahr,Olfml3,Ifi207,Ncoa7,Rnd3,Mndal,Hdc,Myadm,Ifi203,Mmd,Wars,Ifi208,Btg2,Ifi211,Ifi204,Scyl2,Rtn1,Adam19,Plat |
| 1.800e-05 | -10.93 | GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_DN | MSigDB lists | GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_DN | 182 | 32 | 15632 | 1249 |
4930523C07Rik,Lnpep,Klf2,Plekha2,Icosl,Akt3,Tlr1,Dgka,Uba7,Dck,Ms4a6d,Rcsd1,Gtpbp2,Notch2,Cd82,Tmem123,Lrrc8c,Cnn2,Syk,Arid5a,Fcgr2b,Ap3b1,Ccng2,Itga4,Sell,P2ry14,Traf5,Trp53i11,Pde3b,Lpcat2,Cd38,Aff1 |
| 1.800e-05 | -10.93 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | 182 | 32 | 15632 | 1249 |
Stat5a,Armcx6,Spsb1,Eif2ak2,Nr4a1,Parp9,Rsad2,Dhx58,Tor1aip2,Egr2,Ifi44,Ifih1,Rtp4,Mcm10,Mxd1,Pml,Ifit1,Ncoa7,Tle3,Gnb4,Plod2,Tuba4a,Oas2,Rab10,Isg20,Pstpip2,Trip13,St3gal1,Smox,Ptgir,Lhx2,Trafd1 |
| 1.800e-05 | -10.93 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_DN | 182 | 32 | 15632 | 1249 |
Slc25a25,Nxf1,Trim13,Prdx5,Cxcl14,Bcl2a1d,Ifrd1,Ppp2r5a,Cited2,Jun,Bcl2a1b,Nr4a1,Dusp1,Klf6,Tnf,Xcr1,Plaur,Tnip1,Vcam1,Bcl2a1a,Cxcl1,Cdc42ep4,Kcna3,Rac3,Ptprj,Rnf19a,Ppp4r2,Pdgfb,Irf7,Cnp,Gch1,Hsd17b12 |
| 1.800e-05 | -10.93 | GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDC_UP | 182 | 32 | 15632 | 1249 |
Ext1,Parp12,Stat4,Sh3bp4,Csrp1,Ccne1,Jarid2,Ccnj,Plekha2,Irf8,Ubr4,Ppp1r15a,Gca,Dek,Cflar,Cacna1d,Tfec,Lrrc8c,Pik3cd,Ddx4,Cox18,Katna1,Ly75,Prokr1,Ythdf1,Plod3,Myo10,Atp11b,Gda,Mcm10,Aldh1b1,Kat2b |
| 1.800e-05 | -10.93 | GSE360_CTRL_VS_T_GONDII_MAC_DN | MSigDB lists | GSE360_CTRL_VS_T_GONDII_MAC_DN | 182 | 32 | 15632 | 1249 |
Oasl1,Ell2,Trib1,Odc1,Rcan1,Ifit1bl2,Ccne1,Ikbkg,Plk2,Gna15,Inpp5b,Zfp36,Flnb,Cxcl2,Mapkapk2,Upp1,Cd83,Crlf3,Traf5,Gbp2,Ezr,Tnf,Ifit1bl1,Phldb1,Fos,Tspan3,Slc2a1,Hmga1,Ikzf1,Sdc2,Cers6,Ppfia3 |
| 1.800e-05 | -10.93 | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN | 182 | 32 | 15632 | 1249 |
Inpp1,Cflar,Notch2,Slc31a1,Lyn,Ifi204,Ifi208,Ifi211,Il18rap,Ifi203,Jarid2,Lcn2,Mndal,Ifi207,Enpp4,Atp2b4,Crim1,Notch1,Ifi214,Phip,Rhoq,Rab11fip1,Cebpd,Syk,Ifi213,Aoah,Ifi209,Birc2,Tcf4,Ifi205,Rhbdf2,Arid5a |
| 1.800e-05 | -10.93 | GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | MSigDB lists | GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | 182 | 32 | 15632 | 1249 |
Il12b,Zc3h12a,Itpkc,Traf3ip2,Trem1,Elmod2,Birc3,Fcgr4,Ifit1bl2,Il12rb1,Leng9,Htra1,Ddx58,Stat2,Mul1,Ddx60,H2-Q7,Aim2,Pml,Hck,Zc3hav1,Tnfaip3,Il27,Il15,H2-Q6,Birc2,Ankrd17,Eif2ak2,Spn,Ifit1bl1,H2-Q4,Dhx58 |
| 1.800e-05 | -10.93 | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | 182 | 32 | 15632 | 1249 |
Acvr1b,Fcho2,Cdc42ep4,Azi2,Socs3,Zc3h12a,Dyrk2,5430427O19Rik,Znrf1,Gbp7,Ankib1,Arid4a,Tnfrsf1b,Stoml1,Xaf1,Kctd12,Akt3,Etv3,Mcoln2,Clcn5,Dnase1l3,Tspo,Arid5a,Rhof,Tcf4,Tiparp,Gsdmd,Gramd1a,Glipr2,Tapbp,Pde1b,Prkce |
| 1.800e-05 | -10.93 | GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN | 182 | 32 | 15632 | 1249 |
Casp2,Rasgrp1,Birc3,Eif4g2,Rnaset2a,Samsn1,Tmem123,Tnfsf10,Bambi,Dek,Ap3m2,Rnaset2b,Ldha,Dennd2a,Tmod3,Pim2,Crkl,Arid5b,Gsr,Acvr1,Tra2a,Hivep2,Timp1,Ahr,Mdfic,Rbl1,Fas,Abr,Il4ra,Prnp,Ccnd2,Atp11a |
| 1.802e-05 | -10.92 | immunoglobulin mediated immune response | biological process | GO:0016064 | 79 | 17 | 20694 | 1406 |
C1ra,Cd74,Cd55,C3,Fcgr2b,Fcgr1,Pou2f2,H2-Ab1,Swap70,Icosl,Batf,Myd88,Fgl2,Irf7,Nod2,Il4ra,C1rl |
| 1.809e-05 | -10.92 | VARELA_ZMPSTE24_TARGETS_UP | MSigDB lists | VARELA_ZMPSTE24_TARGETS_UP | 37 | 12 | 15632 | 1249 |
Mapkapk2,Atf3,Cd14,Pim3,Cdkn1a,Tnfrsf1b,Gadd45b,Klf3,Myc,Ddit4,Btg2,Gadd45g |
| 1.809e-05 | -10.92 | WEINMANN_ADAPTATION_TO_HYPOXIA_DN | MSigDB lists | WEINMANN_ADAPTATION_TO_HYPOXIA_DN | 37 | 12 | 15632 | 1249 |
Hspa1a,Slc16a3,Sod2,Hspa2,Pla2g4a,Il6,Il1a,Ier3,Cd55,Plaur,Vegfc,Sdc4 |
| 1.809e-05 | -10.92 | GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | 37 | 12 | 15632 | 1249 |
Il1b,Nlrp3,Il12b,Tnfsf4,Malt1,H2-Q7,Il12rb1,Rsad2,Fzd5,Traf2,H2-Q6,H2-Q4 |
| 1.826e-05 | -10.91 | endothelium development | biological process | GO:0003158 | 87 | 18 | 20694 | 1406 |
Acvrl1,Met,Myd88,Plod3,Rapgef2,Acvr1,Kdm6b,Rap2c,Notch1,Ezr,Kdr,F11r,Clic4,Pdgfb,Myadm,Pdpn,Icam1,Col18a1 |
| 1.848e-05 | -10.90 | GO_JNK_CASCADE | MSigDB lists | GO_JNK_CASCADE | 75 | 18 | 15632 | 1249 |
Mdfic,Daxx,Irak2,Nod1,Mul1,Map2k4,Adora2b,Tab2,Trib1,Ripk2,Crkl,Ptger4,Nod2,Dbnl,Ikbkg,Syk,Tnf,Map3k6 |
| 1.849e-05 | -10.90 | KARLSSON_TGFB1_TARGETS_UP | MSigDB lists | KARLSSON_TGFB1_TARGETS_UP | 111 | 23 | 15632 | 1249 |
Pmepa1,Esd,Ppa1,Naa25,Ptk2,Flnb,Ext1,Eef1e1,Plk2,Cacybp,Lrp8,Myc,Mmp14,Cycs,Phgdh,Gadd45g,Arhgap26,Srm,Klf6,Hsph1,Dpy19l1,Zyx,Timp1 |
| 1.849e-05 | -10.90 | GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_UP | MSigDB lists | GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_UP | 174 | 31 | 15632 | 1249 |
Rgs3,Gys1,Slc30a1,Isg15,Malt1,Ccnd1,Optn,Gpr68,Nr3c1,Mmp14,Nr4a1,Gadd45b,Slc16a3,Pfkl,Cxcl1,Ptgs2,Serpinb9,Tlr3,Dusp5,Slc31a1,Cxcl2,Fzd1,Stx11,Ddit4,Nfkbib,Timeless,Scn1b,Piezo1,Marco,Plk2,Tnfrsf1b |
| 1.852e-05 | -10.90 | ROZANOV_MMP14_TARGETS_UP | MSigDB lists | ROZANOV_MMP14_TARGETS_UP | 233 | 38 | 15632 | 1249 |
Smox,Uaca,Oas1g,Denr,Rab20,Tlr2,Pik3cd,Gbp2b,Hcls1,Frmd6,Snx10,Eno2,Psd4,Plk2,Plod2,Ddit4,Btg2,Isg20,Oas1a,Jag1,Adora2a,Col18a1,Nupr1,Ccnd2,Hif1a,Arrdc4,Nr1h3,Cd83,Col4a2,Slamf7,Plac8,Cst7,Tagln,Nr3c1,Mmp14,Il4i1,Errfi1,Rin2 |
| 1.870e-05 | -10.89 | GO_PLASMA_MEMBRANE_RAFT | MSigDB lists | GO_PLASMA_MEMBRANE_RAFT | 82 | 19 | 15632 | 1249 |
Hck,Atp2b4,Spred1,Htr2a,Jak2,Adrb2,Ptgs2,Hmox1,Lrp8,Sele,Ptch1,Slc2a1,Cav1,P2ry12,Lcp2,Lrp4,Src,Lipe,Ezr |
| 1.886e-05 | -10.88 | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | 166 | 30 | 15632 | 1249 |
Sla,Gnb4,Zc3hav1,Dnase1l3,Pgs1,Ddx60,Fgr,Prkce,Rab11fip1,Il6,Myc,Mdn1,Parp14,Ccng2,Cept1,Fam43a,Nfkb2,Rbms1,Dr1,Snn,Usp31,Herc6,Crkl,St3gal1,Myadm,Hk1,Sik3,Klf2,Plekhg1,Irf8 |
| 1.894e-05 | -10.87 | MARSON_FOXP3_TARGETS_DN | MSigDB lists | MARSON_FOXP3_TARGETS_DN | 49 | 14 | 15632 | 1249 |
Rcl1,Pde3b,Slfn3,Jak2,Malt1,Stx6,Rnf19a,Nfkbie,Nfkbid,Myc,Slfn4,Gch1,Dusp6,Gadd45b |
| 1.916e-05 | -10.86 | PEREZ_TP63_TARGETS | MSigDB lists | PEREZ_TP63_TARGETS | 304 | 46 | 15632 | 1249 |
Casz1,Ass1,Bcl2l11,Fam43a,Cxcl14,Psd,Nxf1,Znrf3,Cx3cl1,Egr1,Col18a1,Bcor,Foxp4,Adap2,Ifit3,Rasgrp1,Syne2,Jag1,Ksr1,Ifit3b,Acsl1,Socs3,Igf1r,Col27a1,Hsph1,Stk40,Arhgap26,Rab11fip1,Egr2,Micall2,Arg2,Atp11a,Spata13,Csrnp1,Mxd1,Rab3ip,Apaf1,Bmp2,Fzd1,Vasn,Cdc42ep4,Rcan1,Ptprj,St3gal1,Bambi,Il1rn |
| 1.930e-05 | -10.86 | positive regulation of protein catabolic process | biological process | GO:0045732 | 213 | 32 | 20694 | 1406 |
Tnfrsf1b,Ier3,Rnf139,Mdm2,Tiparp,Arel1,Il1b,Gclc,Ppp2r3a,Rnf19b,Cop1,Trib3,Ptk2,Gja1,Tmem67,Trim30a,Nupr1,Psmd10,Tnfaip3,Trib1,Dnajb2,Hspa1b,Plk2,Rnf19a,Ldlr,Ctsc,Ezr,Hspa1a,Plk3,Tnf,Rnf14,Ankib1 |
| 1.946e-05 | -10.85 | GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_DN | MSigDB lists | GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_DN | 191 | 33 | 15632 | 1249 |
Ddx58,Ccnd2,Spata13,Usp18,Hlx,Prdm1,Relb,Rnf34,Crlf3,Plau,Sgk3,Arhgef3,Rhof,P2ry13,Trim36,Nr4a1,Stat5a,Cst7,Errfi1,Rin2,Mid1,Rab21,Dnajb4,Arid5b,Ptprj,Dnaja2,Zhx2,Hdc,Snx10,Rgl1,Ccne1,Pla2g7,Slc2a6 |
| 1.956e-05 | -10.84 | GO_VACUOLE | MSigDB lists | GO_VACUOLE | 1070 | 123 | 15632 | 1249 |
Cd74,Tab2,Atp11a,Gnb4,Sgk3,Myd88,Sla,Cd14,Lipg,Tnfaip3,Tnf,H2-Q6,Rab21,Micall2,Rab11fip1,Slc39a4,Cp,Tlr3,Crkl,Slc31a1,Nr4a3,Vcam1,Ikbke,Irak2,Mitd1,Slc29a3,Acp2,Il1b,H2-Eb1,Gja1,Fzd5,Atp6v1d,Irf7,Pdgfrb,Map2k1,Rab10,Wdfy1,H2-Aa,Rapgef2,Snx2,Vasn,Mmp13,Sdc1,Pikfyve,Il15,Sdc4,Cd34,Gpc1,Slc48a1,Atp11b,Zc3hav1,Ass1,Sqstm1,Trip10,Ctsc,Mmp14,Optn,Vcan,Ap3b1,Tlr9,Dgkh,Dram1,Lpar1,Lyn,Jak2,Znrf1,Clcn7,Rap2c,Ldlr,Pmepa1,Cav1,Trim21,Ociad1,Mmd,Stx6,Slc30a4,H2-Q7,Pml,Calcrl,Cd164,Clcn5,Hck,Src,Ehd1,Plekhf2,Ifnar1,Acpp,Slc15a3,Rffl,Rab9,Dbnl,Rnf19b,H2-Ab1,Scyl2,Fpr1,Snx10,Slc31a2,Myo1b,Rnaset2a,Inpp5b,Antxr1,Hap1,Arrdc4,Fcgr1,Chmp4b,H2-Q4,Ezr,Flt1,Rab32,Agrn,Irgm2,Il4i1,Sdc2,Nox1,Mefv,Pik3cd,Adrb2,Kdr,Rnaset2b,Rabgef1,Lnpep,P2ry2,Rasgrp1 |
| 1.960e-05 | -10.84 | 25A_SYNTH_3 | prosite domains | PS50152 | 13 | 7 | 13278 | 1037 |
Oas2,Oasl2,Oas1b,Oas1a,Oas3,Oas1g,Oasl1 |
| 1.987e-05 | -10.83 | B cell differentiation | biological process | GO:0030183 | 121 | 22 | 20694 | 1406 |
Atm,Ifna2,Ifna5,Ifna4,Ifna6,Slamf8,H2-Ab1,Ikzf1,Ptprj,Dock10,Tnfaip3,Notch2,Ifnb1,Ahr,Clcf1,Bcl6,Plcl2,Pou2f2,Ifna1,Ptpn2,Malt1,Hhex |
| 2.004e-05 | -10.82 | GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | 550 | 72 | 15632 | 1249 |
Slc9a1,Nfkbib,Sirt1,Rhou,Rabgef1,Rnf31,Tnfsf14,Cav1,Il10,Casp8,Rims3,Jak2,Hcls1,Stard7,Cdkn1a,Tlr9,Dyrk2,Lyn,Tlr2,Il6,Prkce,Ezr,Nfkbia,Bcl2l11,Ccl12,Syk,Psmd10,Prdx1,Angpt1,Stxbp1,Ubash3b,Mul1,Il4ra,Nlrp3,Cdk5r1,G3bp2,Csf3,Fzd1,Hap1,Txn1,Fzd5,Map2k1,Bambi,Sec24b,Keap1,Il1b,Tlr3,Hmox1,Zc3h12a,Ptgs2,Adora2b,Il18,Il12b,Cxcl10,Rab21,Micall2,Mdm2,Rbpms,Nfkbie,Tnf,Ehd1,Src,Mdfic,Plagl2,Parp10,Nfkbil1,Plk3,Pml,Rnf139,Ddx58,Sphk1,Fgr |
| 2.013e-05 | -10.81 | anatomical structure formation involved in morphogenesis | biological process | GO:0048646 | 913 | 95 | 20694 | 1406 |
Map2k1,Casp1,Bcl2l11,Egr3,Sema3c,Tmod3,Gpc1,Mthfr,Flt1,Notch1,Mthfd1l,Il18,Zc3h12a,Hmox1,Tlr2,Inhba,Spint2,Nr4a1,Acvr1,Ccl2,Plau,Adgrg6,Apaf1,Hdac1,Hopx,Pdpn,Ets2,Vegfc,Phactr4,Tulp3,Nectin2,Prkx,Ptk2,Pdgfrb,Fzd5,Lrp8,Serpine1,Col18a1,Sema4c,Edn1,Socs7,Sema4a,Nrp2,Thbs1,Lhx2,Ptgs2,Cflar,Vasp,Hif1a,Itga5,Nfkb2,Atm,Hhex,Pik3r6,Txnrd1,Sirt1,Csrp1,Fam20c,Nr4a3,Cdk5r1,Ahr,Cav1,Cemip2,Ptch1,Lmo4,Itgav,Casp3,Sdc4,Ccl12,Pikfyve,Casp8,Angpt1,Col4a2,Acvrl1,Ift57,Cx3cl1,Fzd1,Jun,Egr2,Kdr,Pde3b,Cited2,Syk,Tnfaip2,Kdm6b,Junb,Ifitm1,Sec24b,Bcl6,Jmjd6,Calcrl,Notch2,Wars,Nox1,Clic4 |
| 2.014e-05 | -10.81 | negative regulation of cellular component movement | biological process | GO:0051271 | 314 | 42 | 20694 | 1406 |
Svbp,Ptk2,Il1rn,Notch1,Clic4,Timp1,Stap1,Spint2,Sema4c,Serpine1,Trib1,Cd200,Rabgef1,Gpr18,Fas,Rgcc,Sinhcaf,Thbs1,Sema3c,Slamf8,Evl,Acvrl1,Stat3,Cx3cr1,Dach1,D1Ertd622e,Sema4a,Ptprj,Rap2c,Ccl12,Mecp2,Spred1,Cited2,Pdgfb,Ptger4,Dusp1,Lrch1,Abr,Cx3cl1,Cnn2,Tmod3,Jag1 |
| 2.017e-05 | -10.81 | GSE17721_POLYIC_VS_CPG_24H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_24H_BMDC_UP | 183 | 32 | 15632 | 1249 |
Nfil3,Cdkn1a,Snn,Rnaset2b,Epsti1,Il15ra,Tmem219,Clic4,Actb,Slc25a22,Slamf8,Aida,Clec5a,Psmb6,Prdm9,Crkl,Atp10a,Ube2l6,Bcl9,Mov10,Rnaset2a,Sesn3,Rhoc,Chmp4b,Aff1,Rbm43,Sav1,Ciita,P2ry14,Fabp3,Irf2,Traf2 |
| 2.017e-05 | -10.81 | GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | 183 | 32 | 15632 | 1249 |
Bcl2a1b,Ass1,Ifit1bl1,Rhof,Rab11fip1,Stard5,Cpd,Gpr68,Bcl2a1d,Tapbp,Itga4,Slc30a1,Pde3b,Nod1,Tap1,Relb,Ccl5,Card6,Ifit1bl2,Sap30,Btg2,Akt3,Casp2,Stx6,Mmd,Filip1l,Cxcl10,Grina,Nfkb2,Bcl2a1a,Gfi1,Igf1r |
| 2.017e-05 | -10.81 | GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN | MSigDB lists | GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN | 183 | 32 | 15632 | 1249 |
Atp13a1,Irf4,Egr2,Ppp2r5a,Gpr18,Mtus1,Aoah,Mvp,Pde3b,Ddx58,Slc30a1,Jmjd6,Bcor,Col18a1,Oas1a,Parp12,Wdr59,St3gal5,Lcp2,Klf2,Hopx,Cep350,Junb,Tuba4a,Ccl5,Sec24b,Tax1bp1,Rap2c,Kdm6b,Egr3,Oas1g,Stat1 |
| 2.017e-05 | -10.81 | GSE40273_EOS_KO_VS_WT_TREG_DN | MSigDB lists | GSE40273_EOS_KO_VS_WT_TREG_DN | 183 | 32 | 15632 | 1249 |
Jdp2,Sipa1l1,Plekha2,Trip13,Atxn7l1,Ptprj,Ptk2,Lyn,Asb13,Rcsd1,Mcm6,Sh3bgrl2,Bcl2a1a,Slfn9,Vrk2,Cnn2,Parp8,Adhfe1,Bcl2a1b,Otud1,Slfn8,Lrch1,Pnp2,S1pr2,Optn,Treml2,Bcl2a1d,Ift57,Stxbp1,Usp25,Icam1,Dcp2 |
| 2.017e-05 | -10.81 | GSE6674_ANTI_IGM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_ANTI_IGM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | 183 | 32 | 15632 | 1249 |
Gadd45g,Pcx,Myc,Ccdc86,Cish,Slc2a1,Arid5a,Homer1,Txnrd1,Sod2,Srm,Tnf,Spred1,Pim3,Socs1,Prnp,Lrp8,Hk2,Eef1e1,Noc4l,Slc7a5,Asns,Slc4a7,Hsd17b7,Cdkn1a,Gpd2,Spata5l1,Mthfd2,Trib3,Rcn1,Pim1,Larp1 |
| 2.017e-05 | -10.81 | GSE39556_CD8A_DC_VS_NK_CELL_UP | MSigDB lists | GSE39556_CD8A_DC_VS_NK_CELL_UP | 183 | 32 | 15632 | 1249 |
Dmxl2,St3gal6,Ccnd2,Prnp,Mdfic,Atp2b4,Gng11,Cd34,Cyfip1,Gypc,Hivep2,Cers6,Nr3c1,D1Ertd622e,Mthfd2,Acsl1,Rcn1,Cacnb3,Traf3ip2,Slc31a1,Ldha,Tnfsf4,Lcp2,Cav1,Map4k4,Tuba4a,Txn1,Rgl1,Slc25a12,Trip13,Plscr1,Trim14 |
| 2.017e-05 | -10.81 | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN | 183 | 32 | 15632 | 1249 |
Hk2,Bst1,Rabgef1,Sipa1l1,Layn,Rel,Rgs1,Clic4,Dcbld2,Ripk2,Zc3h12a,Fndc3a,Ptk2,Spire1,Ttc39b,St7,Trib3,Adora2b,Prokr1,Atp13a1,Acvrl1,Errfi1,Gypc,N4bp1,Hspa1a,Fos,Traf5,Zbtb5,Egr1,Rars,Slc30a4,Aldh1b1 |
| 2.021e-05 | -10.81 | GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS | 62 | 16 | 15632 | 1249 |
Ass1,Tnf,Cav1,Klf2,Il10,Il6,Stat3,Edn1,Zc3h12a,Ptgs2,Icam1,Tspo,Jak2,Cd34,Il1b,Atp2b4 |
| 2.052e-05 | -10.79 | GO_T_HELPER_1_TYPE_IMMUNE_RESPONSE | MSigDB lists | GO_T_HELPER_1_TYPE_IMMUNE_RESPONSE | 17 | 8 | 15632 | 1249 |
Tlr6,H2-Eb1,Ebi3,Sema4a,Il12b,Il18,Relb,Il18bp |
| 2.052e-05 | -10.79 | BIOCARTA_LAIR_PATHWAY | MSigDB lists | BIOCARTA_LAIR_PATHWAY | 17 | 8 | 15632 | 1249 |
Il6,Vcam1,Il1a,Itgal,Icam1,C3,Itga4,Tnf |
| 2.052e-05 | -10.79 | PID_ANTHRAX_PATHWAY | MSigDB lists | PID_ANTHRAX_PATHWAY | 17 | 8 | 15632 | 1249 |
Map2k4,Il18,Map2k1,Casp1,Tnf,Il1b,Antxr1,Vcam1 |
| 2.052e-05 | -10.79 | AMIT_EGF_RESPONSE_40_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_40_MCF10A | 17 | 8 | 15632 | 1249 |
Egr3,Klf6,Dusp5,Egr1,Fos,Jun,Thbs1,Zfp36 |
| 2.052e-05 | -10.79 | BIOCARTA_IL22BP_PATHWAY | MSigDB lists | BIOCARTA_IL22BP_PATHWAY | 17 | 8 | 15632 | 1249 |
Stat2,Socs3,Stat1,Stat5a,Tyk2,Stat4,Jak2,Stat3 |
| 2.060e-05 | -10.79 | regulation of granulocyte chemotaxis | biological process | GO:0071622 | 50 | 13 | 20694 | 1406 |
Ccl2,Thbs1,Il1b,Ptprj,Cd74,Edn1,Cmklr1,Bst1,Csf1,Ccl5,Cx3cl1,Sell,Nod2 |
| 2.074e-05 | -10.78 | IL-6 signaling Pathway | WikiPathways | WP387 | 99 | 26 | 4813 | 540 |
Ppp2r1b,Stat3,Hdac1,Mapkapk2,Fgr,Ppp2r2a,Socs3,Cdk5r1,Ppp2r5a,Lyn,Stat5a,Casp3,Jun,Il6,Tyk2,Nfkb1,Daxx,Fos,Jak2,Hck,Ptk2,Stat1,Cd40,Map2k4,Map2k1,Ppp2r3a |
| 2.076e-05 | -10.78 | Guanylate-bd_C_sf | interpro domains | IPR036543 | 14 | 7 | 19984 | 1430 |
Gbp2,Gbp9,Gbp4,Gbp2b,Gbp7,Gbp3,Gbp8 |
| 2.076e-05 | -10.78 | 2-5-oligoadenylate_synth_N | interpro domains | IPR006116 | 14 | 7 | 19984 | 1430 |
Oas1a,Oas3,Oasl1,Oas1b,Oasl2,Oas2,Oas1g |
| 2.078e-05 | -10.78 | GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_UP | MSigDB lists | GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_UP | 175 | 31 | 15632 | 1249 |
Lif,Nfkbiz,Ccnd2,Crlf3,Pim3,Rras2,Prpf4,Spred1,Rgs3,Etv5,Hivep2,Klf6,Slc2a1,Ets2,Znfx1,Dusp2,Cd55,Nr4a3,Trib3,Sec24a,Cmpk2,Stip1,Dusp6,Ppp1r15b,Ccne1,Mthfd1l,Rrs1,Samsn1,Pdss1,Zeb1,Stat4 |
| 2.078e-05 | -10.78 | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_UP | MSigDB lists | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_UP | 175 | 31 | 15632 | 1249 |
Tnfsf14,Casp4,Inpp5b,Isg20,Trim14,Tlr1,Ifi35,Dtx2,Filip1l,Phyh,Plcl2,Znrf1,Clcn7,Ikbke,Fmnl2,Nr4a1,Parp8,Otud1,Fos,Zyx,Gpr35,Kdm5b,Nfkbie,Ccnd1,Tapbp,Dtx3l,St3gal6,Il4ra,Nod1,Crim1,Gbp2 |
| 2.078e-05 | -10.78 | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN | 175 | 31 | 15632 | 1249 |
B3gnt5,Gpr68,Mllt6,Peli1,Rffl,Gpsm2,Ppp1r14b,Ezr,Ifit1bl1,Gbp2,Tspo,Fbxo4,Slco3a1,Spata13,Zfp281,Cyth3,Rhoh,Cdkn2d,Il18rap,Stat4,Lgals9,Card6,Tuba4a,4930523C07Rik,Mthfd1l,Ifit1bl2,Dusp28,Pgk1,Il2rg,Ms4a6d,Dyrk2 |
| 2.078e-05 | -10.78 | GO_CELLULAR_RESPONSE_TO_OXIDATIVE_STRESS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_OXIDATIVE_STRESS | 175 | 31 | 15632 | 1249 |
Il18bp,Mdm2,Prdx5,Nqo1,Bnip3,Il6,Fos,Traf2,Hspa1a,Src,Klf6,Sod2,Stau1,Etv5,Tnfaip3,Prdx1,Pnpt1,Hif1a,Kat2b,Sphk1,Fas,Pml,Sirt1,Il18rap,Klf2,Ccl5,Vrk2,Jak2,Kdm6b,Zc3h12a,Hmox1 |
| 2.090e-05 | -10.78 | regulation of epithelial cell differentiation | biological process | GO:0030856 | 148 | 25 | 20694 | 1406 |
Acvrl1,Tnf,Jag1,Il1a,Stat5a,Mafg,Abcb1a,Lif,Zeb1,Prkx,Il1b,Notch1,Mmp9,Zfp36,Maff,Ccnd1,Keap1,Klf7,Serpine1,Cav1,Ptch1,Errfi1,Foxp4,Mycl,S1pr2 |
| 2.098e-05 | -10.77 | negative regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001243 | 96 | 19 | 20694 | 1406 |
Map2k1,Plaur,Cd74,Grina,Bcl2a1a,Src,Sirt1,Mmp9,Hdac1,Mdm2,Hsph1,Ptgs2,Bcl2a1d,Cdkn2d,Sod2,Ikbkg,Bcl2a1b,Hif1a,Dnaja1 |
| 2.114e-05 | -10.76 | Regulation of necroptotic cell death | REACTOME pathways | R-MMU-5675482 | 12 | 7 | 8608 | 757 |
Tnfsf10,Birc2,Traf2,Birc3,Cflar,Fas,Casp8 |
| 2.151e-05 | -10.75 | regulation of cyclin-dependent protein kinase activity | biological process | GO:1904029 | 88 | 18 | 20694 | 1406 |
Pdgfb,Ccnd2,Casp3,Kat2b,Cdkn2d,Tnfaip3,Ccng2,Rgcc,Cdk5r1,Psmd10,Ccnd1,Pim1,Src,Actb,Ccne1,Cdkn1a,Hhex,Ccnj |
| 2.171e-05 | -10.74 | Caspase_cys_AS | interpro domains | IPR033139 | 10 | 6 | 19984 | 1430 |
Casp4,Casp3,Casp2,Casp1,Casp8,Casp7 |
| 2.171e-05 | -10.74 | Pept_C14_p10 | interpro domains | IPR002138 | 10 | 6 | 19984 | 1430 |
Casp7,Casp3,Casp2,Casp1,Casp8,Casp4 |
| 2.172e-05 | -10.74 | GO_ERYTHROCYTE_HOMEOSTASIS | MSigDB lists | GO_ERYTHROCYTE_HOMEOSTASIS | 69 | 17 | 15632 | 1249 |
Lyn,Jmjd6,Hmox1,Tmod3,Adar,Hcls1,Jak2,Prdx1,Bcl6,Ptpn2,Klf2,Axl,Arid4a,Inhba,Ampd3,Ikzf1,Casp3 |
| 2.172e-05 | -10.74 | BROWNE_HCMV_INFECTION_2HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_2HR_UP | 32 | 11 | 15632 | 1249 |
Cxcl2,Egr1,Gch1,Nfkbia,Nr4a1,Atf3,Map3k8,Nr4a3,Fos,Irf1,Icam1 |
| 2.176e-05 | -10.74 | Signaling by PDGF | REACTOME pathways | R-MMU-186797 | 322 | 51 | 8608 | 757 |
Psmb10,Nck1,Phlpp1,Psmd10,Psmb9,Stat5a,Pik3cd,Crkl,Spred1,Src,Phlpp2,Psme2b,Angpt1,Plat,Prkce,Pdgfc,Nr4a1,Ppp2r1b,Ier3,Psmb8,Mdm2,Stat3,Ptk2,Met,Trib3,Cd80,Psma6,Psme2,Rasgrp1,Pde1b,Rapgef2,Stat1,Dusp6,Psmb6,Dusp5,Prkar2b,Psme1,Pdgfb,Thbs1,Kitl,Cdkn1a,Col4a2,Irs2,Ppp2r5a,Rictor,Pdgfrb,Il2rg,Ksr1,Map2k1,Jak2,Cd86 |
| 2.177e-05 | -10.73 | GO_ADENYL_NUCLEOTIDE_BINDING | MSigDB lists | GO_ADENYL_NUCLEOTIDE_BINDING | 1404 | 154 | 15632 | 1249 |
Flt1,Map3k6,Cenpe,Nlrc5,Nod2,Prkce,Abcb1a,Nlrp3,Mapkapk2,Rars,Pgs1,Tap1,Atp2b4,Mark2,Gclc,Pfkfb3,Ciita,P2ry2,Mcm9,Pdk3,Met,Oas1a,Ube2e2,Trip13,Ep400,Ksr1,Akt3,Pik3cd,Acsl1,Acvr1b,Dyrk2,Kif5c,Itpkc,Dck,Fignl2,Etnk1,Prkar2b,Pfkl,Igf1r,Fam20c,Kdr,Actb,Hspa1a,Swap70,Hsph1,Ehd1,Src,Dync1h1,Axl,Mlkl,Stk40,Atp13a1,Acvrl1,Acvr1,Mdn1,Fgr,Sphk1,Ddx58,Ube2e1,Hck,Myo10,Clcn5,Ripk3,Nod1,Ascc3,Myo1b,Plk2,Map4k4,Mthfd1l,Oas2,Tyk2,Dgka,Uba7,Hk2,Wars,Kif3c,Spata5l1,Pim1,Ak4,Oas1g,Smc5,Dnaja2,Scyl2,Abcc4,Cmpk2,Slfn9,Prkx,Acsl5,Slfn3,Dnaja1,Nlrc4,Syk,Ass1,Eif2ak2,Pcx,Katna1,Slfn8,Pikfyve,Tpx2,Papss2,Nek6,Ddx60,Me1,Atp11b,Slfn5,Hk3,Kif9,Pim3,Sik3,Mov10,Hk1,Atm,Tor3a,Srxn1,Ddx4,Lyn,Map2k4,Trib1,Pim2,Oasl1,Dgkh,Ptk2,Vrk2,Abcc1,Chd9,Clcn7,Jak2,Oas3,Abcc5,Hspa2,Dhx58,Tlk2,Ifih1,Atp11a,Plk3,Irak3,Apaf1,Ube2f,Sgk3,Map2k1,Pdgfrb,Slfn4,Tap2,Asns,Pde4b,Rapgef2,Mcm6,Map3k8,Trib3,Ripk2,Atp10a,Pgk1,Irak2,Ikbke |
| 2.221e-05 | -10.71 | IL-1 Signaling Pathway | WikiPathways | WP37 | 37 | 14 | 4813 | 540 |
Nfkbia,Casp1,Il1rn,Il1b,Map2k1,Irak2,Peli1,Nfkb1,Nfkbib,Tab2,Irak3,Myd88,Sqstm1,Il1a |
| 2.238e-05 | -10.71 | GO_ENZYME_REGULATOR_ACTIVITY | MSigDB lists | GO_ENZYME_REGULATOR_ACTIVITY | 854 | 102 | 15632 | 1249 |
Cst7,Casp1,Hsph1,Birc2,Gpsm2,Timp1,Rgs14,Cish,Dbnl,Tbc1d1,Casp3,Ccnd1,Rhoh,Psme1,Malt1,Socs1,Ahsa1,Bmp2,Nod1,Notch1,Daxx,Crim1,Pik3r6,Sipa1l1,Pdgfb,Inpp5b,Serpinb9,Nsmaf,Cxcl10,Serpinb2,Elmod2,Pik3r5,Flrt3,Dock4,Jun,Ppp2r5a,Prkce,Spry2,Abr,Pttg1,Cdc42ep2,Atp2b4,Mark2,Ccne1,Birc3,Tnfsf14,Dcp1a,Socs3,Rgs1,Cflar,Prkar2b,Socs7,Tagap,Prdx5,Errfi1,Arhgap26,Asap3,Rgs3,Apaf1,Ccl5,Serpine1,Map2k1,Ppp1r15a,Tor1aip1,Flrt2,Ppp2r3a,Spint2,Tbc1d13,Rapgef2,Sh3bp4,Cdc42ep4,Rcan1,Trib3,Ralgds,Ppp2r2a,Htr2b,Ppp1r14b,Eif2ak2,Trip10,Nlrc4,Mmp14,Ctsc,Gclm,Tor1aip2,Phactr4,Rin2,Cdkn2d,Nck1,Cdk5r1,Kat2b,Spred1,Adap2,Cav1,Psme2,Slpi,Ppp4r2,Rap1gap2,Rictor,C3,Trib1,Ppp2r1b,Cdkn1a |
| 2.238e-05 | -10.71 | DNA binding | molecular function | GO:0003677 | 2042 | 188 | 20217 | 1400 |
Hif1a,Stat4,Ifi207,Pcgf5,Setdb2,Pou2f2,Batf,Rbbp8,Lhx2,Nfxl1,Mxd1,Fos,Kdm5b,Mycl,Rabgef1,Zfp513,Ifi214,Nupr1,Jarid2,Bcl6,Jdp2,Polr2g,Helz2,Bbx,Zfp281,Tshz1,Hlx,Klf6,Hopx,Trim21,Foxp4,Tlr9,Notch1,Irf2,Dr1,Atf3,Csrnp1,Ets2,Zfp36,Phf6,Jun,Nfil3,Ifi213,Samhd1,Nlrp3,Ift57,Klf8,Junb,Sphk1,Ddx58,Ddx60,Nr3c1,Rbms1,Hinfp,Zhx2,Irf4,Tet2,Relb,Rel,Plscr1,Snapc1,Hmga2,Stat5a,Fubp1,Zbp1,Irf8,Pml,Tcf4,Hhex,Zc3h12a,Etv6,Mecp2,Zfp319,Prdm9,Taf4b,Hivep3,Plagl2,Klf2,Tfec,Zfp945,Dek,9130023H24Rik,Ep400,Oasl1,Arid4a,Dhx58,Mcm9,Sde2,Irf7,Xrn1,Lmo4,Hdac1,Pou3f1,Casz1,Hmgn3,Tnf,Adar,Rfx5,Ifih1,Mcm6,Eno1,Aim2,Top3a,Irf1,Hivep2,Batf2,Ifi208,Hmga1,Tnfaip3,Nfkb2,Tiparp,Ciita,Radx,Zeb1,Nr4a3,Dach1,Trim30a,Cgas,Zfp40,Mafg,Aebp2,H3f3b,Sp100,Arid5b,Plagl1,Tcea1,Tal2,Ifi209,Arid5a,Klf3,Dnase1l3,Mndal,Mcm10,Timeless,Egr1,Kat2b,Rbl1,Ifi204,Egr3,Klf7,Sp110,Etv5,Ahrr,Egr2,Ifi203,Gfi1,Ikzf1,Sap30,Spic,Sod2,Ifi205,Slpi,Prdx5,Sp140,Bcor,Smg7,Sirt1,Nlrc5,Nr1h3,Nr4a1,Cers6,Max,Chd9,Ier2,Spen,Pbx1,Nfkb1,Fosb,Swap70,Mafk,Prdm1,Atm,Aff1,Ifi211,Cebpd,Kdm6b,Stat3,Maff,Myc,Zbtb5,Psip1,Mier3,Stat1,Etv3,Stat2,Ahr,Crlf3,Zfp800 |
| 2.246e-05 | -10.70 | GO_LEUKOCYTE_PROLIFERATION | MSigDB lists | GO_LEUKOCYTE_PROLIFERATION | 83 | 19 | 15632 | 1249 |
Ifna6,Csf1,Ifna5,Ifnb1,Cd40,Tnfsf14,Cd86,Il10,Ifna1,Il15,Plcl2,Ifna2,Ripk2,Ebi3,Tnfsf4,Malt1,Azi2,Psmb10,Cd180 |
| 2.256e-05 | -10.70 | GO_REGULATION_OF_NEURON_DEATH | MSigDB lists | GO_REGULATION_OF_NEURON_DEATH | 235 | 38 | 15632 | 1249 |
Nr4a3,Map2k4,Cpeb4,Hmox1,Clcf1,Jak2,Rel,Atm,Ikbkg,Ccl5,Sirt1,Csf3,Casp2,Egln3,Ddit4,Rilpl1,Btg2,Hif1a,Cdk5r1,Stxbp1,Daxx,Chmp4b,Angpt1,Cd34,Rras2,Gclc,Traf2,Jun,Axl,Ccl12,Bcl2l11,Sod2,Mecp2,Nqo1,Stat3,Casp3,Gclm,Il6 |
| 2.256e-05 | -10.70 | LEE_LIVER_CANCER_MYC_E2F1_UP | MSigDB lists | LEE_LIVER_CANCER_MYC_E2F1_UP | 56 | 15 | 15632 | 1249 |
Plscr1,Ifi44,H2-Aa,Cish,Bcl2a1d,Slc13a3,Ifit2,Bcl2a1b,Lcn2,Bcl2a1a,Plat,Tmem176b,Cd74,Usp18,Icam1 |
| 2.259e-05 | -10.70 | GSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_UP | 184 | 32 | 15632 | 1249 |
Ptafr,Acsl1,Mafg,Lyn,Ms4a6d,Dram1,Etnk1,Hmgcs1,Pmepa1,Agpat4,Idi1,Il1rn,Med21,Heatr6,Dusp6,Bst1,Pdss1,Procr,Slc30a1,Arl4a,Enpp4,Etv5,Slc48a1,Extl2,Cyfip1,Txnrd1,Sqstm1,Dpy19l1,Chst11,Rai14,Rhoq,Spry2 |
| 2.259e-05 | -10.70 | GSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_DN | MSigDB lists | GSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_DN | 184 | 32 | 15632 | 1249 |
Tal2,Ifit1,Gbp2,Relb,Rhoh,Nkiras1,Cyth3,Isg15,Fgl2,Sqstm1,Bcl2l11,Dnaja1,Tnfsf10,Ccl4,Esd,Ptges,Wdr43,Tcea1,Ptk2,Tmod3,Rtn1,Rcn1,Il12b,Serpinb9,Mafg,Isg20,Reps1,Rnf19a,Kctd12,Gdf15,Rnf14,Myo1b |
| 2.259e-05 | -10.70 | GSE5589_WT_VS_IL6_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | 184 | 32 | 15632 | 1249 |
Scn1b,Procr,Mmp13,Ednrb,Plk2,Bcl2a1a,Pf4,Rtn1,Ptgir,Ell2,Clec4d,St7,Rcan1,Fcgr2b,Ccr3,Gpr68,Cpd,Bcl2a1d,Cd200r4,Cst7,Spryd7,Bcl2a1b,Spn,Cx3cr1,Cutc,Cd14,Prdx1,Aff1,Rhoh,Marcksl1,Papss2,Sgms2 |
| 2.259e-05 | -10.70 | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP | 184 | 32 | 15632 | 1249 |
Acp2,Map3k8,Il18,Ptgir,Traf3ip2,Asah2,Cd86,Irf8,Birc3,Jarid2,Sesn3,Mdfic,Clec4e,Usp18,Kmo,Irs2,Slco3a1,P2ry14,Sell,Slc30a4,Tmem176b,Ddx60,B3gnt5,Spry2,Nr3c1,Ifi44,Slc44a1,Bbx,Prkce,Bcl6,Parp8,Casp1 |
| 2.259e-05 | -10.70 | GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 184 | 32 | 15632 | 1249 |
Wdr43,Gng12,Vegfc,Rac3,Ppa1,Ptprj,Ifit3b,Rcn1,Irf1,Snx10,Lap3,Ifit3,Hvcn1,Nupr1,Tmem176b,Psmb10,Nr1h3,Sphk1,Usp18,Sat1,Ctsc,Pcx,Nqo1,C1ra,Rin2,Tagln,Adhfe1,Axl,Rhbdf2,Mrpl52,Spic,Psmb9 |
| 2.268e-05 | -10.69 | cytokine production involved in immune response | biological process | GO:0002367 | 25 | 9 | 20694 | 1406 |
Il18rap,Tlr2,Nlrp3,Il12b,Dennd1b,Nod2,Trem1,Il18,Sirt1 |
| 2.268e-05 | -10.69 | antigen processing and presentation of exogenous peptide antigen | biological process | GO:0002478 | 25 | 9 | 20694 | 1406 |
Fcgr1,H2-Aa,H2-Ab1,H2-Eb1,Cd74,Tapbp,Tap1,Tap2,Fcgr2b |
| 2.270e-05 | -10.69 | cellular response to oxygen levels | biological process | GO:0071453 | 122 | 22 | 20694 | 1406 |
Sirt1,Adrb2,Slc9a1,Myc,Bnip3,Cpeb4,Notch1,Pdk3,Hif1a,Nox1,Higd1a,Cited2,Ak4,Fas,Rgcc,Vasn,Prkce,Plk3,Egr1,Fam162a,Pgk1,Cav1 |
| 2.274e-05 | -10.69 | GO_NEGATIVE_REGULATION_OF_PROTEOLYSIS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEOLYSIS | 297 | 45 | 15632 | 1249 |
Slpi,Ifi211,Trim21,Ifi203,Atm,Birc3,Casp8,Mndal,Il10,Tnfsf14,Dnajb2,C3,Mmp9,Ifi204,Il6,Nlrc4,Ifi207,Cdkn2d,Ifi214,Pttg1,Ifi208,Spint2,Serpine1,Ppp1r15a,Thbs1,Serpinb2,Plat,Plaur,Cd55,Serpinb9,Rffl,Prdx5,Tlk2,Mdm2,Cst7,N4bp1,Ifi213,Src,Ifi205,Ifi209,Birc2,Timp1,Rnf34,Crim1,Pml |
| 2.282e-05 | -10.69 | MODULE_407 | MSigDB lists | MODULE_407 | 13 | 7 | 15632 | 1249 |
Dusp2,Dusp8,Rgs3,Dusp4,Gadd45g,Dusp6,Fpr1 |
| 2.282e-05 | -10.69 | LIU_IL13_PRIMING_MODEL | MSigDB lists | LIU_IL13_PRIMING_MODEL | 13 | 7 | 15632 | 1249 |
Egr1,Plk3,Cdyl,Jmjd6,Jag1,Etv5,Fos |
| 2.284e-05 | -10.69 | GO_T_CELL_DIFFERENTIATION | MSigDB lists | GO_T_CELL_DIFFERENTIATION | 120 | 24 | 15632 | 1249 |
Fzd5,Pik3cd,Clec4d,Il12b,Sema4a,Irf1,Ptger4,Ptpn2,Syk,Spn,Rsad2,Il6,Tnfsf8,Irf4,Jmjd6,Cd74,Egr1,Rhoh,Fas,Relb,Ripk3,Clec4e,Il15,Batf |
| 2.317e-05 | -10.67 | actin cytoskeleton organization | biological process | GO:0030036 | 477 | 57 | 20694 | 1406 |
Phactr4,Tnf,Rhou,Arhgap26,Nck1,Fmnl2,Pstpip2,Evl,Zyx,Ezr,Triobp,Sipa1l1,Rhoq,Antxr1,Daam1,S1pr2,Frmd6,Tmsb10,Carmil1,Pdgfrb,Actb,Pdlim7,Fscn1,Bcl6,Rhoc,Rnd1,Rac3,Marcks,Pdgfb,Cnn2,Tmod3,Vasp,Abr,Cflar,Whamm,Plek,Myo1b,Src,Cdc42ep2,Casp4,Hcls1,Tpm4,Micall2,F11r,Rhof,Dbnl,Flnb,Rnd3,Spire1,Rictor,Swap70,Palld,Csrp1,Diaph2,Rhoh,Trip10,Cnn3 |
| 2.333e-05 | -10.67 | GSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_DN | 176 | 31 | 15632 | 1249 |
Cd200,Stat1,St3gal1,Ier3,Trib3,Rgs1,Gch1,Eno2,Ifit1bl2,Vps54,Casp4,Procr,Bcorl1,Ube2e2,Palld,Traf1,Upp1,F11r,Ubash3b,Pbx1,Rbms2,Col4a2,Gbp2,Ifit1,Axl,Ifit1bl1,Znfx1,Rai14,Parp14,Treml2,Phlpp1 |
| 2.333e-05 | -10.67 | GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_UP | MSigDB lists | GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_UP | 176 | 31 | 15632 | 1249 |
Phlpp2,Inpp5b,Card6,Col27a1,Adam19,Bcl2a1a,Agpat4,Il18,Nr4a3,Tlr2,Il12b,Peli1,Slc39a4,Aftph,Carhsp1,Rab9,Bcl2a1d,Sele,Bcl2a1b,Plekhf2,Otud1,Gnb4,Samhd1,Zc3hav1,Chmp4b,Daxx,Apba1,Mxd1,Atf3,Rtp4,Prnp |
| 2.333e-05 | -10.67 | GSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP | MSigDB lists | GSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP | 176 | 31 | 15632 | 1249 |
Sdc2,Pcx,Dusp8,Timp1,Tspan3,Swap70,Bcl6,Ptpn2,Hivep2,Ppfibp1,Ciita,Bmp2,Hif1a,Gbe1,Pikfyve,Palld,Stat4,Phlda1,Htra1,Cd86,Gna15,Flrt2,Ptch1,Gem,Atm,Ltbp2,Zhx2,Thbs1,Irf1,Trib1,Smox |
| 2.333e-05 | -10.67 | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN | 176 | 31 | 15632 | 1249 |
Mapkapk2,Icam1,Clcn5,Cd164,Atp2b4,Crim1,Mdfic,Dnase1l3,Slc7a11,Ppp1r14b,Cd302,Tcf4,Ctsc,Cers6,Atp10a,Dck,Dusp5,Tgfbi,Gfi1,Txn1,Dach1,Higd1a,Gna15,Sema3c,Irf8,Irf7,Flnb,Slc7a5,Jag1,Sh3bp4,Egln3 |
| 2.333e-05 | -10.67 | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | 176 | 31 | 15632 | 1249 |
Akt3,Bcl9,Rapgef2,Rasgrp1,Birc3,Jarid2,Daam1,Cd274,Ascc3,Bcl2a1a,Rap2c,Ikbke,Cpeb4,Ptger4,Ptgir,Dusp5,Ifi44,Bcl2a1d,Dusp1,Armcx6,Nr4a1,Bcl2a1b,Gypc,Rgs14,Swap70,Cited2,Myo10,Prdm1,Lrp8,Mthfr,Kdm4a |
| 2.333e-05 | -10.67 | GSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | 176 | 31 | 15632 | 1249 |
Ccr1,Lap3,Sipa1l1,Gna15,Slc7a5,Nfkbib,Dusp5,Ier3,Osgin2,Clic4,Nfkb2,Rgs1,Zcchc2,Gtpbp2,Ppp2r2a,Wdr43,Tcea1,Esd,Abcc5,Gsdmd,Fam43a,Dusp1,Cd40,Hspa1a,Ptpn2,Tiparp,Il4i1,Phgdh,Bfar,Tnfaip3,Clcn5 |
| 2.346e-05 | -10.66 | extracellular region part | cellular component | GO:0044421 | 1851 | 170 | 20747 | 1409 |
Ccl8,C3,Serpina3f,Procr,Mmp14,Glipr2,Rnaset2b,Itga4,Kmo,Tgfbi,F10,Sema4c,Cd40,Ccl7,Fabp3,Col27a1,Slpi,Gbp7,Il1rn,Pgk1,Cxcl2,Flrt2,Il12b,Gpc1,Mmp13,Htra1,Cxcl9,Axl,Ccl2,Lrp8,Tpx2,Acpp,Lipe,Cd180,H60b,Tnfsf4,Il1b,Ccl22,Clcf1,Ifnb1,Asah2,Pdgfb,Pla2g7,C1rl,Tnf,Inhba,Lad1,Flt1,Serpinb9b,Hp,Csf1,Ccl12,C1ra,Il4ra,Plod3,Ifna4,Nos2,Usb1,Lipg,Cxcl11,Osm,Vcam1,Il18,Col18a1,Cd34,Hsd17b12,Sema4a,Gsdmd,Thbs1,Met,Fas,Ifna6,Tnc,Bmp2,Gbp8,Arrdc4,Il6,Nampt,Serpine1,Timp1,Irgm2,Plat,Ppfia3,Adam19,Ccl4,Cxcl10,Ebi3,Ccl5,Gbp2b,Plscr1,Cpd,Tnfsf9,H2-T22,Vasn,Ifna2,Raet1e,Lif,Cxcl3,Serpinb6b,Ccl3,Il10,Tnfsf10,H2-Q6,Il15,Lgals9,S100a8,Tnfsf8,H2-T24,Flrt3,Il27,Ifna5,Csf3,Ldlr,Cd86,Sele,Ccr3,Cnp,Pf4,Iigp1,H2-Q4,Cp,Cst7,H2-Q7,Tnfsf14,Cxcl14,Pdgfc,Serpinb9,Vcan,Saa3,Gbp2,Lox,Serpinb2,Lcn2,H2-M2,Cx3cl1,Tnfsf15,Ltbp2,H2-T10,Col11a2,Fam20c,Tsku,Smpdl3b,Ntng2,Ifna1,Vegfc,Gbp3,Gdf15,Plau,Msr1,Serpina3g,Agrn,Ccl9,Icam1,Kitl,Col4a2,Gbp9,Rnaset2a,Cd274,Cd14,Sema3c,Cxcl1,Il18bp,Hilpda,Spn,Mmp25,Il1a,Ctsc,Edn1,Mmp9,Angpt1 |
| 2.378e-05 | -10.65 | GO_NEGATIVE_REGULATION_OF_BINDING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_BINDING | 128 | 25 | 15632 | 1249 |
Ifi214,Itga4,Ifi207,Ifi205,Jun,Ifi209,Nfkbia,Ifit2,Ifi213,Ifit1bl1,Adrb2,Ifi204,Hmox1,Lhx2,Mitd1,Jak2,Mndal,Il10,Cav1,Ifit1bl2,Ifi203,Slpi,Ifi208,Pdgfb,Ifi211 |
| 2.378e-05 | -10.65 | JOHNSTONE_PARVB_TARGETS_2_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_UP | 128 | 25 | 15632 | 1249 |
Cd74,Isg15,Ddx60,H2-Q7,Ncoa7,Tnfaip3,Znfx1,H2-Q6,Cited2,Zyx,Ifit2,Ifit1bl1,H2-Q4,Txnrd1,Oaf,Grina,Ifit3b,Oasl1,Actb,Plat,Ifit3,Serpine1,Ifit1bl2,Ccrl2,Ube2l6 |
| 2.378e-05 | -10.65 | GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 128 | 25 | 15632 | 1249 |
Ripk2,Psmb6,H2-Ab1,Ptprj,Pik3cd,Cacnb3,Rnf31,Ikbkg,Nfkb1,Psmb8,H2-Eb1,Pde4b,Lcp2,H2-Aa,Psme2,Psme1,Malt1,Nck1,Psmb10,Tab2,Nfkbia,Psmd10,Psmb9,Dennd1b,Psma6 |
| 2.383e-05 | -10.64 | regulation of epithelial cell migration | biological process | GO:0010632 | 225 | 33 | 20694 | 1406 |
Evl,Map4k4,Plk2,Thbs1,Src,Met,Angpt1,Acvrl1,Sema4a,Adora2b,Pdgfb,Vegfc,Spred1,Plpp3,Mecp2,Hif1a,Kdr,Stat5a,Glipr2,Jun,Ptgs2,Svbp,Sirt1,Mmp9,Zc3h12a,Ptk2,Akt3,Notch1,Cd40,Serpine1,Prkce,Hmox1,Rgcc |
| 2.405e-05 | -10.64 | negative regulation of CD4-positive, alpha-beta T cell activation | biological process | GO:2000515 | 31 | 10 | 20694 | 1406 |
Lgals9,Hlx,Il4ra,Tarm1,Cd274,Tnfsf4,Bcl6,Zc3h12a,Arg2,Irf1 |
| 2.405e-05 | -10.64 | regulation of macrophage chemotaxis | biological process | GO:0010758 | 31 | 10 | 20694 | 1406 |
Mtus1,Slamf8,Thbs1,Ccl2,Stap1,Cmklr1,Cx3cl1,Csf1,Ptprj,Ccl5 |
| 2.405e-05 | -10.64 | alpha-beta T cell differentiation involved in immune response | biological process | GO:0002293 | 31 | 10 | 20694 | 1406 |
Gadd45g,Spn,Ptger4,Il6,Stat3,Batf,Irf4,Relb,Sema4a,Il12b |
| 2.422e-05 | -10.63 | ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY | MSigDB lists | ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY | 1396 | 153 | 15632 | 1249 |
Prkce,Stard5,Pdpn,Ikzf1,Taf4b,Bcl2l11,Nfkbia,Adhfe1,Fam43a,Cenpe,Ifit1bl1,Tet2,Angpt1,Sass6,Etv3,Tmtc2,Trim13,Dcp1a,Stat4,Ube2e2,Smpdl3b,Pla2g7,Mier3,Plekha2,Lcn2,Tnfsf14,Trim34a,Tnfaip2,Kdr,Zcchc2,Cflar,Tagap,Igf1r,Etnk1,Azi2,Ms4a6d,Carhsp1,Bcl2a1d,C1ra,Kdm5b,Ccnd1,Lztfl1,Tank,Bmp2,Nod1,Gbp2,Relb,Notch1,Jmjd6,Dtx3l,Sertad3,Stat2,Tlr1,Inpp5b,Btg2,Uba7,Hk2,Gch1,Sesn3,Card6,Arid4a,Nampt,Ifit1bl2,Slc7a8,Tnfsf10,Bcl2a1a,Cmklr1,Glrx,Trafd1,Dio2,Igf2bp2,Lacc1,Ttc39b,Mmp14,Katna1,Mid1,Parp9,Phlpp1,Psd,Bcl2a1b,Ass1,Psip1,Sod2,Spsb1,D16Ertd472e,Casz1,Spic,Kif9,Trp53i11,Atp11b,Mpp7,Papss2,Kat2b,Csf1,Syne2,Etv6,Zscan29,Ednrb,S100a8,Nos2,Rel,Mov10,Ust,Cd82,Tax1bp1,Dnajb2,Nfil3,Pmepa1,Uaca,Dram1,Cpeb4,Map2k4,Tnip3,Ubtd2,Ccng2,Gpr68,Rbpms,Phldb1,Usp53,Slc25a37,Bcl6,Tcf4,Mtus1,Pbx1,Plagl2,Mvp,Pdgfc,Rab3ip,Prrg4,Nupr1,Arg2,Ifih1,Cd74,Piezo1,Sap30,Cxcl2,Car13,Eya4,Gdf15,Ccr1,Cdyl,Flrt2,Hopx,Slc29a3,Plat,Ralgds,Kitl,Inpp1,Snn,Epsti1,Tlr3,Cdc42ep4,Fcho2 |
| 2.425e-05 | -10.63 | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN | 193 | 33 | 15632 | 1249 |
Cenpe,Ifi213,Sp140,Ifi209,Ifi205,Rbbp8,Fut8,Ccr3,Stap1,Tpx2,Ifi214,Gmppb,Batf,Slc16a1,Ifi207,Cnp,Lap3,Mndal,Ifi211,Ifi208,Wars,Ifi203,Ebi3,Ifi204,Slc43a3,Trib1,Mcm6,Cflar,Adam19,Acp2,Nfil3,Keap1,Gfi1 |
| 2.425e-05 | -10.63 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 193 | 33 | 15632 | 1249 |
Slc2a1,Bcl2a1b,Aebp2,Bcl2a1d,Acvrl1,Gadd45g,Rhoq,Jmjd6,Gbe1,Slc30a4,Mapkapk2,Tpi1,Hopx,Irf8,Rnf14,Bst1,Adora2a,Hk2,Ddit4,Sap30,Trib3,Rcan1,Mthfd2,Serpinb9,Pdzd11,Map3k8,Cd200,Dck,Fam162a,Glrx,Bcl2a1a,Idi1,Clic4 |
| 2.437e-05 | -10.62 | GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_DN | MSigDB lists | GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_DN | 136 | 26 | 15632 | 1249 |
Cyfip1,Cx3cr1,Arhgap26,Dock10,Irf4,Fcgr2b,Ctsc,Ubash3b,Xrn1,Slamf7,Cd80,Itgal,Adap2,Rap1gap2,Il18rap,Bcorl1,Med13,Serpinb9,Gpd2,Mmp25,Dgkh,Cflar,Tmem67,Osbpl3,Gcnt2,Rap2c |
| 2.437e-05 | -10.62 | GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | MSigDB lists | GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | 136 | 26 | 15632 | 1249 |
Hif1a,Csrnp1,Egr1,St3gal3,Plau,Pim3,Tiparp,Jun,Casz1,Nr4a1,Tnf,Dusp2,Egr2,Nr4a3,Ier3,Socs3,Ptgir,Egr3,Tax1bp1,Ccl4,Cxcl1,Osm,Fosb,Ppp1r15a,Fzd1,Btg2 |
| 2.439e-05 | -10.62 | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP | MSigDB lists | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP | 50 | 14 | 15632 | 1249 |
Sat1,Pla2g7,Rsad2,Dusp6,Sod2,Ifit3,Rnaset2a,Samsn1,Cxcl1,Rbms1,Rnaset2b,F11r,Ifit3b,Papss2 |
| 2.439e-05 | -10.62 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | MSigDB lists | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | 50 | 14 | 15632 | 1249 |
Ccl12,Ccl5,Ccr1,Cx3cr1,Cxcl2,Ccr3,Cxcl10,Cx3cl1,Ccl22,Ccl3,Xcr1,Pf4,Ccl4,Cxcl1 |
| 2.439e-05 | -10.62 | GSE37532_WT_VS_PPARG_KO_LN_TCONV_DN | MSigDB lists | GSE37532_WT_VS_PPARG_KO_LN_TCONV_DN | 160 | 29 | 15632 | 1249 |
Phf11d,Serpinb9,Glrx,Dek,Clic4,Itgal,Tap2,Plek,Myadm,Ccl5,Smpdl3b,Csf1,Plscr1,Cd38,Ncoa7,Phf11c,Nod1,Sav1,Phf11a,Swap70,Psmb9,Rbbp8,Phf11b,Cenpe,Casp1,Itgav,N4bp1,Cox17,Ap3b1 |
| 2.441e-05 | -10.62 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 27 | 10 | 15632 | 1249 |
Dhx58,Tnfaip3,Htra1,Mul1,Trib1,Ifit1bl1,Nfkbil1,Ifit1bl2,Prdm1,Eif2ak2 |
| 2.441e-05 | -10.62 | GO_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION | MSigDB lists | GO_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION | 27 | 10 | 15632 | 1249 |
Ifnb1,Rsad2,H2-Q6,Traf2,Fzd5,Nlrp3,Malt1,H2-Q7,H2-Q4,Tnfsf4 |
| 2.441e-05 | -10.62 | GO_TUMOR_NECROSIS_FACTOR_RECEPTOR_BINDING | MSigDB lists | GO_TUMOR_NECROSIS_FACTOR_RECEPTOR_BINDING | 27 | 10 | 15632 | 1249 |
Tnfsf15,Tnfsf10,Tnfsf8,Tnfsf14,Traf2,Traf1,Casp8,Tnf,Tnfsf4,Stat1 |
| 2.448e-05 | -10.62 | animal organ morphogenesis | biological process | GO:0009887 | 1026 | 104 | 20694 | 1406 |
Notch2,Zhx2,Tshz1,Igf1r,Fgr,Agrn,Slc4a7,Arid5b,Sec24b,Plod3,Col27a1,Tnf,Fzd1,Jun,Sik3,Kdr,Col11a2,Cited2,Eya4,Pml,Serp1,Angpt1,Ikzf1,Acvrl1,Ift57,Prdm1,Nr4a3,Ahr,Pbx1,Chst11,Cav1,Tmeff1,Htr2b,Itgav,Ptch1,Gja1,Hmga2,Ppp2r3a,Hhex,Tet2,Acp5,Pdgfc,Fam20c,Mdm2,Jag1,Ttc39c,Abr,Hif1a,Casz1,Il6,Bmp2,Thbs1,Nrp2,Timeless,Csf1,Flrt2,Serpine1,Spry2,Ntng2,Tsku,Csrnp1,Edn1,Triobp,Sav1,Prkx,Kdm5b,Clic5,Zeb1,Mmp14,Pdgfrb,Fzd5,Myc,Stat5a,Tnc,Mmp13,Tulp3,Phactr4,Vegfc,Acvr1,Adgrg6,Hdac1,Inhba,Errfi1,Bcor,Crkl,Tdrd7,Notch1,Gfi1,Akt3,Mthfd1l,Tiparp,Stk40,Lrp4,Hlx,Flt1,Lif,Pdgfb,Map2k1,Snx10,Bcl2l11,Stat3,Src,Nr3c1,Sema3c |
| 2.454e-05 | -10.62 | GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | 38 | 12 | 15632 | 1249 |
Cav1,Il10,Hif1a,Zc3h12a,Hp,Ptger4,Hk2,Atp2b4,Tspo,Bnip3,Cd34,Stat3 |
| 2.454e-05 | -10.62 | GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | 38 | 12 | 15632 | 1249 |
Tnfsf4,Malt1,H2-Q7,Nlrp3,Nr4a3,Cd74,Tnfrsf14,H2-Q4,Fzd5,Traf2,H2-Q6,Rsad2 |
| 2.454e-05 | -10.62 | GO_CHEMOKINE_ACTIVITY | MSigDB lists | GO_CHEMOKINE_ACTIVITY | 38 | 12 | 15632 | 1249 |
Cxcl1,Ccl4,Ccl3,Pf4,Ccl22,Cxcl10,Cx3cl1,Ccl2,Cxcl2,Cxcl14,Ccl12,Ccl5 |
| 2.454e-05 | -10.62 | PID_AMB2_NEUTROPHILS_PATHWAY | MSigDB lists | PID_AMB2_NEUTROPHILS_PATHWAY | 38 | 12 | 15632 | 1249 |
Plat,Plau,Hck,Plaur,Mmp9,Lyn,Fgr,Icam1,Il6,Nfkb1,Src,Tnf |
| 2.454e-05 | -10.62 | ST_B_CELL_ANTIGEN_RECEPTOR | MSigDB lists | ST_B_CELL_ANTIGEN_RECEPTOR | 38 | 12 | 15632 | 1249 |
Nfkbie,Nfkbib,Akt3,Map2k1,Syk,Nfkb1,Nfkbia,Nfkb2,Prdx1,Lyn,Pik3cd,Nfkbil1 |
| 2.464e-05 | -10.61 | GSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 152 | 28 | 15632 | 1249 |
Gclc,Batf,Il1a,Stxbp1,Plk3,Rars,Mafk,Gpr84,Rbbp8,Bcl2l11,Ifit1bl1,Ehd1,Tagap,Bambi,Plcl2,Gfpt1,Ripk2,Smox,Larp1,Slc39a14,Ppp4r2,Slc2a6,Srxn1,Sik3,Fosb,Il10,Ifit1bl2,Psat1 |
| 2.464e-05 | -10.61 | GO_POSITIVE_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION | 22 | 9 | 15632 | 1249 |
Rsad2,Tnfsf4,H2-Q4,H2-Q7,Malt1,Fzd5,Traf2,H2-Q6,Nlrp3 |
| 2.464e-05 | -10.61 | HASLINGER_B_CLL_WITH_11Q23_DELETION | MSigDB lists | HASLINGER_B_CLL_WITH_11Q23_DELETION | 22 | 9 | 15632 | 1249 |
Ppp2r1b,Fut8,Ahr,Casp1,Slc4a7,Atm,Sik3,Birc2,Dmxl2 |
| 2.478e-05 | -10.61 | positive regulation of phagocytosis | biological process | GO:0050766 | 73 | 16 | 20694 | 1406 |
Il2rg,Nod2,Abr,Tnf,Il15,Stap1,Il15ra,Fpr2,C3,Ptk2,Ptprj,Il1b,Fcgr2b,Fcgr1,Cd300lf,Ccl2 |
| 2.479e-05 | -10.60 | PID_CXCR4_PATHWAY | MSigDB lists | PID_CXCR4_PATHWAY | 98 | 21 | 15632 | 1249 |
Stat3,Rictor,Itgav,Pik3r5,Src,Stat5a,Pik3r6,Rgs1,Jak2,Rhoc,Hck,Itga5,Mmp9,Stat1,Ptk2,Itga4,Fgr,Pik3cd,Lyn,Itga9,Stat2 |
| 2.479e-05 | -10.60 | ROESSLER_LIVER_CANCER_METASTASIS_UP | MSigDB lists | ROESSLER_LIVER_CANCER_METASTASIS_UP | 98 | 21 | 15632 | 1249 |
Gys1,Gclc,Gcnt2,Myd88,Clcn7,Gpd2,Itga9,Cyth3,Mmp9,Irf2,Stoml1,Usp12,G3bp2,Ccr3,Fut8,Csf3r,Nfkb1,Tshz1,Map3k6,Cenpe,Eno2 |
| 2.481e-05 | -10.60 | cellular response to reactive oxygen species | biological process | GO:0034614 | 114 | 21 | 20694 | 1406 |
Ripk3,Cflar,Fos,Sod2,Tnfaip3,Jun,Prdx5,Traf2,Sphk1,Il6,Kdm6b,Axl,Lcn2,Sirt1,Mmp9,Src,Nqo1,Pdgfrb,Prdx1,Bnip3,Thbs1 |
| 2.486e-05 | -10.60 | GTACTGT_MIR101 | MSigDB lists | GTACTGT_MIR101 | 236 | 38 | 15632 | 1249 |
Etv5,Spred1,Cdk5r1,Mxd1,Aebp2,Rin2,Tlk2,Prkce,Ankrd17,Fos,N4bp1,Abcc5,Bcl2l11,Flrt3,Dusp1,Dcbld2,Rap2c,Rgs1,Dr1,Zcchc2,Gpr85,Ptgs2,Mppe1,Trib1,G3bp2,Phlda1,Piezo1,Tmeff1,Bcl9,Ddit4,Ptch1,Flrt2,Gja1,Dcun1d3,Jdp2,Ccnj,Cdyl,Junb |
| 2.503e-05 | -10.60 | REACTOME_SIGNALING_BY_PDGF | MSigDB lists | REACTOME_SIGNALING_BY_PDGF | 113 | 23 | 15632 | 1249 |
Trib3,Stat1,Crkl,Nck1,Cdkn1a,Prkar2b,Pdgfc,Plat,Thbs1,Col4a2,Map2k1,Pdgfrb,Nr4a1,Src,Stat5a,Rictor,Mdm2,Phlpp1,Prkce,Pde1b,Pdgfb,Stat3,Akt3 |
| 2.503e-05 | -10.60 | RB_DN.V1_DN | MSigDB lists | RB_DN.V1_DN | 113 | 23 | 15632 | 1249 |
Mmp9,Nfil3,Ppp2r1b,Cav1,P4ha1,Myadm,Tuba4a,Mmp13,Slc7a5,Psme2,Pdgfb,Ddit4,Psmb10,Usp18,Col18a1,Psme1,Dusp14,Mvp,Serp1,Agrn,Cish,Tnc,Ctsc |
| 2.510e-05 | -10.59 | GERHOLD_ADIPOGENESIS_DN | MSigDB lists | GERHOLD_ADIPOGENESIS_DN | 63 | 16 | 15632 | 1249 |
Samhd1,Thbs1,Plat,Tnfaip2,Ier3,Il4ra,Ccnd2,Sdc1,Cebpd,Ifrd1,Vcan,Ccnd1,Mmp14,Casp8,Pdgfrb,Ccl12 |
| 2.524e-05 | -10.59 | VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_DN | MSigDB lists | VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_DN | 44 | 13 | 15632 | 1249 |
Ifi208,Ifi211,Ifi203,Ifi213,Ifi209,Mndal,Ifi205,Clic4,Pde3b,Ifi207,Ifi214,Aldh1b1,Ifi204 |
| 2.524e-05 | -10.59 | BROWNE_HCMV_INFECTION_30MIN_UP | MSigDB lists | BROWNE_HCMV_INFECTION_30MIN_UP | 44 | 13 | 15632 | 1249 |
Cd38,Tfec,Thbs1,Kitl,Egr3,Socs3,Eya4,Zfp36,Egr2,Fos,Lcn2,Junb,Dusp1 |
| 2.526e-05 | -10.59 | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN | 185 | 32 | 15632 | 1249 |
Clic4,Gca,Cmklr1,Clcf1,Wdr43,Agpat4,Itga5,Slc31a1,C3,Rtn1,Tlr2,Acvr1b,Mob3b,St3gal5,Slc2a6,Tlr1,Alas1,Stx11,Ccr1,S100a8,Tspo,Sav1,Hk3,Nupr1,Nr1h3,F11r,Fpr2,Rhoq,Dhx58,Fgl2,Syk,Tspan3 |
| 2.526e-05 | -10.59 | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP | MSigDB lists | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP | 185 | 32 | 15632 | 1249 |
Zc3h12a,Etnk1,Arid5b,Dnajb4,Cacnb3,Irf1,Cox18,Tax1bp1,Snapc1,Sp110,Ednrb,Junb,Pdgfrb,Gem,Cd86,Col11a2,Gpr132,Cysltr2,Il18rap,Inhba,Icam1,Upp1,1600014C10Rik,Mdfic,Myo10,Zc3hav1,Lrp4,Map3k6,Klf6,Plac8,Jun,Spic |
| 2.542e-05 | -10.58 | p53 signaling | WikiPathways | WP2902 | 67 | 20 | 4813 | 540 |
Pmaip1,Sesn3,Gadd45b,Cop1,Atm,Ccnd1,Ccne1,Ccnd2,Casp8,Serpine1,Cdkn1a,Thbs1,Fas,Apaf1,Ccng2,Cycs,Casp3,Mdm2,Gadd45g,Cd82 |
| 2.553e-05 | -10.58 | GO_UBIQUITIN_LIKE_PROTEIN_LIGASE_BINDING | MSigDB lists | GO_UBIQUITIN_LIKE_PROTEIN_LIGASE_BINDING | 245 | 39 | 15632 | 1249 |
Fzd5,Casp8,Ikbkg,Tnfrsf1b,Rnf31,Trib3,Acvr1b,Trib1,Lyn,Uchl1,Dio2,Prkar2b,Dnajb2,Cdkn1a,Ikbke,Traf2,Cd40,Dnaja1,Tank,Hspa1a,Nfkbia,Sqstm1,Mdm2,Triobp,Mid1,Rffl,Egr2,Kdm4a,Hif1a,Mul1,Traf1,Usp25,Pml,Tpi1,Tnfrsf14,Daxx,Traf5,Rnf34,Ube2f |
| 2.605e-05 | -10.56 | GO_NEGATIVE_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION | 91 | 20 | 15632 | 1249 |
Tnfsf4,Hlx,Adrb2,Il4ra,Ubash3b,Cd74,Prnp,Irf1,Tnfrsf14,Spn,H2-Eb1,Ptpn2,Bcl6,Cd274,Il10,Peli1,Casp3,Pde5a,Ifnb1,Nfkbid |
| 2.608e-05 | -10.55 | regulation of ribonuclease activity | biological process | GO:0060700 | 15 | 7 | 20694 | 1406 |
Oas1g,Oasl2,Oasl1,Oas1b,Oas2,Oas3,Oas1a |
| 2.608e-05 | -10.55 | regulation of response to interferon-gamma | biological process | GO:0060330 | 15 | 7 | 20694 | 1406 |
Socs1,Parp9,Parp14,Irgm2,Ptpn2,Irgm1,Nlrc5 |
| 2.608e-05 | -10.55 | adhesion of symbiont to host | biological process | GO:0044406 | 15 | 7 | 20694 | 1406 |
Nectin2,Icam1,Gbp3,Gbp2b,Gbp9,Gbp7,Gbp2 |
| 2.608e-05 | -10.55 | macrophage chemotaxis | biological process | GO:0048246 | 15 | 7 | 20694 | 1406 |
Gpr35,Ccl12,Ednrb,Cx3cl1,Ccl3,Ccl2,Cx3cr1 |
| 2.608e-05 | -10.55 | regulation of interferon-gamma-mediated signaling pathway | biological process | GO:0060334 | 15 | 7 | 20694 | 1406 |
Nlrc5,Irgm1,Ptpn2,Parp14,Irgm2,Parp9,Socs1 |
| 2.613e-05 | -10.55 | negative regulation of cell migration | biological process | GO:0030336 | 266 | 37 | 20694 | 1406 |
Evl,Thbs1,Slamf8,Stat3,Acvrl1,D1Ertd622e,Dach1,Cx3cr1,Ptprj,Rap2c,Ccl12,Spred1,Cited2,Pdgfb,Ptger4,Mecp2,Dusp1,Abr,Lrch1,Jag1,Cx3cl1,Cnn2,Svbp,Ptk2,Notch1,Il1rn,Clic4,Timp1,Stap1,Serpine1,Trib1,Rgcc,Fas,Sinhcaf,Gpr18,Rabgef1,Cd200 |
| 2.617e-05 | -10.55 | GSE3982_MAC_VS_TH1_UP | MSigDB lists | GSE3982_MAC_VS_TH1_UP | 177 | 31 | 15632 | 1249 |
Trim13,Plau,Cd14,Swap70,Cyfip1,P2ry13,Ifnar1,Plekhf2,Itgav,Ogfrl1,Sat1,Spry2,Dennd1b,Ly75,Phyh,Dram1,Hp,Rtn1,Hmox1,Gng12,Dek,Clcn7,Gca,Chd9,Rabgef1,Fcgr4,Mmd,Usp12,Eya4,Cysltr2,Htra1 |
| 2.617e-05 | -10.55 | GSE28130_ACTIVATED_VS_INDUCEED_TREG_UP | MSigDB lists | GSE28130_ACTIVATED_VS_INDUCEED_TREG_UP | 177 | 31 | 15632 | 1249 |
Endod1,Il1rn,Ccl4,Prkx,Gfi1,Acp2,Nfil3,Slc4a7,Il10,Lcp2,Med13,Spint2,Ppp2r3a,Palld,Upp1,Sell,Socs1,P2ry14,Sla,Flt1,Casp1,Bcl2l11,Jun,Tcf4,Pla2g4a,Rhoq,Lrch1,Myc,Vcan,Ifrd1,Rsad2 |
| 2.617e-05 | -10.55 | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_2H_DN | 177 | 31 | 15632 | 1249 |
Tmeff1,Atxn7l1,Snx2,Vasp,Zc3h12c,Hopx,Gem,Fam102b,Zcchc2,Prkx,Chd9,Zc3h12a,Tmem229b,Rab21,D1Ertd622e,Stap1,Optn,4932438A13Rik,Mecp2,Dtnb,Dse,P2ry12,Arhgef3,Rhof,Rras2,Batf,Crlf3,Hck,Rab19,Hif1a,Cd180 |
| 2.617e-05 | -10.55 | GSE17721_LPS_VS_POLYIC_8H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_8H_BMDC_UP | 177 | 31 | 15632 | 1249 |
Gsr,Stk40,Chst11,Ncoa5,Dusp2,Rffl,Irf4,Psmd10,Sod2,Itgav,Gramd1a,Plagl2,Cd80,Rnd3,Cyth3,Magohb,Trim21,Fubp1,Lmo4,Itgal,Tshz1,Rabgef1,Abcc1,Fam162a,Acsl5,Kif3c,St7,Pdzd11,Hmox1,Kpna3,Hmgcs1 |
| 2.617e-05 | -10.55 | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_UP | 177 | 31 | 15632 | 1249 |
Irgm2,Casp3,Gbp9,Gbp4,Egr2,Rsad2,Plac8,Ddhd1,Ahr,Hhex,Usp18,Dtx3l,Gbp3,Cnn3,Mmp13,Parp12,Hap1,Rasgrp1,Slc13a3,Nampt,Gja1,Il10,Gbp7,Polr2g,Tcea1,Cmpk2,Sp110,Sema4c,Kdm6b,Parp11,Irf1 |
| 2.617e-05 | -10.55 | GSE39556_CD8A_DC_VS_NK_CELL_DN | MSigDB lists | GSE39556_CD8A_DC_VS_NK_CELL_DN | 177 | 31 | 15632 | 1249 |
Il4ra,Kmo,Cd180,Plagl1,Rhoh,Relb,Dnase1l3,Hck,Cd38,Ptpn2,Gpr18,Rapgef5,Fchsd2,Tbc1d1,Irf4,Lyn,Ptafr,Pim2,Cd55,Sp110,Adam19,Cxcl1,Plcl2,Rims3,Daam1,Psd4,Spint2,Cxcl2,Rasgrp1,Oas2,Zfp36 |
| 2.627e-05 | -10.55 | nucleoside binding | molecular function | GO:0001882 | 374 | 48 | 20217 | 1400 |
Nkiras1,Rnd3,Dck,Gbp9,Pnp2,Tgtp1,Rab9,Gbp8,Arl4a,Gbp2b,Rhof,Tuba4a,Rab20,Arl5c,Rnd1,Samhd1,Gem,Mx1,Iigp1,Rras2,Gna15,Rab10,Rhoc,Gmppb,Rhou,Rap2c,Irgq,Ak4,Rac3,Irgm1,Gch1,Arf4,Gtpbp2,Rab19,Hcar2,Rhoq,Ehd1,Rab21,Gbp7,Ciita,Rhoh,Gbp3,Mocs1,Ift22,Rab32,Cgas,Arl5b,Gbp2 |
| 2.627e-05 | -10.55 | Graft-versus-host disease | KEGG pathways | mmu05332 | 63 | 17 | 7931 | 713 |
H2-T22,H2-Q4,H2-Q7,H2-Q6,Cd86,H2-M2,Cd80,H2-T24,H2-Aa,H2-Ab1,Il1a,Fas,Il6,Tnf,Il1b,H2-Eb1,H2-T10 |
| 2.627e-05 | -10.55 | Graft-versus-host disease | KEGG pathways | ko05332 | 63 | 17 | 7931 | 713 |
H2-Q4,H2-T22,H2-T10,Il1b,H2-Eb1,Tnf,Il6,Fas,Il1a,H2-Ab1,H2-Aa,H2-T24,Cd80,H2-M2,H2-Q6,Cd86,H2-Q7 |
| 2.642e-05 | -10.54 | Toll Like Receptor signaling | WikiPathways | WP88 | 33 | 13 | 4813 | 540 |
Tab2,Ikbkg,Tlr3,Nfkb2,Nfkb1,Casp8,Casp3,Irak2,Tlr2,Ikbke,Myd88,Irak3,Eif2ak2 |
| 2.658e-05 | -10.54 | MORI_PRE_BI_LYMPHOCYTE_DN | MSigDB lists | MORI_PRE_BI_LYMPHOCYTE_DN | 70 | 17 | 15632 | 1249 |
Samhd1,Traf5,Lyn,Il4ra,Cd74,Nfkbiz,Rhoq,Zfp36,Btg2,Fcgr2b,Sat1,Tank,Rgs14,Klf2,Nfkb1,Birc3,Jarid2 |
| 2.658e-05 | -10.54 | GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | 70 | 17 | 15632 | 1249 |
Rsad2,Rasgrp1,Il12rb1,Cd40,Fzd5,Traf2,H2-Q6,Tnf,H2-Q4,Il1b,Clcf1,Nlrp3,Il12b,C3,Tnfsf4,H2-Q7,Malt1 |
| 2.666e-05 | -10.53 | CARD | smart domains | SM00114 | 9 | 6 | 9567 | 823 |
Casp2,Card6,Casp1,Birc2,Birc3,Casp4 |
| 2.670e-05 | -10.53 | Th17 cell differentiation | KEGG pathways | ko04659 | 102 | 23 | 7931 | 713 |
Il2rg,Nfkbib,Nfkbia,Stat3,H2-Aa,Irf4,Il12rb1,Ahr,Nfkb1,Tyk2,Jun,Stat1,Il1b,H2-Eb1,Il4ra,Jak2,H2-Ab1,Ikbkg,Il6,Hif1a,Fos,Stat5a,Nfkbie |
| 2.670e-05 | -10.53 | Th17 cell differentiation | KEGG pathways | mmu04659 | 102 | 23 | 7931 | 713 |
Stat5a,Fos,Nfkbie,Il6,Il4ra,H2-Ab1,Ikbkg,Jak2,H2-Eb1,Il1b,Hif1a,Ahr,Stat1,Jun,Tyk2,Nfkb1,Nfkbia,Stat3,Il2rg,Nfkbib,Irf4,Il12rb1,H2-Aa |
| 2.678e-05 | -10.53 | neutrophil activation | biological process | GO:0042119 | 20 | 8 | 20694 | 1406 |
Syk,Dnase1l3,Il18,Fcgr4,Stx11,Il18rap,Il15,Ccl5 |
| 2.678e-05 | -10.53 | regulation of antigen processing and presentation | biological process | GO:0002577 | 20 | 8 | 20694 | 1406 |
H2-Ab1,Fgl2,Thbs1,Tapbpl,Tap2,Nod2,Nod1,Cd74 |
| 2.678e-05 | -10.53 | positive regulation of glial cell proliferation | biological process | GO:0060252 | 20 | 8 | 20694 | 1406 |
Myc,Il6,Lyn,Tspo,Ptk2,Il1b,Etv5,Tnf |
| 2.678e-05 | -10.53 | negative regulation of growth of symbiont in host | biological process | GO:0044130 | 20 | 8 | 20694 | 1406 |
Myd88,Sqstm1,Tnf,Il12b,Tlr2,Irf8,Nod2,Il10 |
| 2.689e-05 | -10.52 | positive regulation of T-helper 2 cell differentiation | biological process | GO:0045630 | 7 | 5 | 20694 | 1406 |
Tnfsf4,Il18,Nlrp3,Il4ra,Il6 |
| 2.738e-05 | -10.51 | positive regulation of cell development | biological process | GO:0010720 | 661 | 73 | 20694 | 1406 |
Tnfrsf1b,Sirt1,Il1b,Scarf1,Notch1,Rgs14,Trip10,Fubp1,Itpr1,Sphk1,Dbnl,Crkl,Myadm,Tlr2,Clcf1,Lyn,Trib1,Rapgef2,Gpr68,Sema3c,Nr3c1,Bmp2,Eif4g2,Map2k1,Hap1,Hif1a,Cyfip1,Il6,Scn1b,Lif,Kdm4a,Mmd,Mul1,Lpar1,Cflar,Myc,Pde5a,Bcl6,Zeb1,Rac3,Mark2,Ptk2,Edn1,Triobp,Nlgn2,Spen,D16Ertd472e,S1pr2,Igf1r,Lrp8,Ccl5,Csf1,Carmil1,Kat2b,Met,Nck1,Hdac1,Etv5,Cx3cr1,Rab21,Kdr,Kif3c,Abcb1a,Mecp2,Vegfc,Tnf,Cx3cl1,P2ry2,Tspo,Tcf4,P2ry12,Ehd1,Fzd1 |
| 2.753e-05 | -10.50 | GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_UP | MSigDB lists | GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_UP | 161 | 29 | 15632 | 1249 |
Tpx2,Kmo,Cd74,Nfkbiz,Tmem176b,Mvp,Cd38,Cd83,Sdc4,Tcf4,Cyfip1,Itpr1,Cenpe,Cpd,Hdac1,Egr2,Myc,Cish,Irf4,Lyn,Slc43a3,Tnip3,Odc1,Pim1,Casp8,Plk2,Hat1,Ppp2r3a,Trip13 |
| 2.753e-05 | -10.50 | GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_DN | MSigDB lists | GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_DN | 161 | 29 | 15632 | 1249 |
Dgka,Tlr1,Zeb1,Ext1,Sipa1l1,Dusp6,Map4k4,Mthfd1l,Wdr43,Ikbke,Filip1l,Cers6,Treml2,Peli1,Myc,Egr2,Fchsd2,Ikzf1,Mdn1,Rnf114,Srm,Plac8,Gramd1a,Rab3ip,Rras2,Sell,Irs2,Etv3,Rhoh |
| 2.790e-05 | -10.49 | GO_RESPONSE_TO_STARVATION | MSigDB lists | GO_RESPONSE_TO_STARVATION | 153 | 28 | 15632 | 1249 |
Ifi207,Upp1,Ifi214,Sphk1,Atf3,Slc39a4,Slc2a1,Ifi205,Jun,Ifi209,Ifi213,Eif2ak2,Cdkn1a,Lrp11,Ifi204,Max,Cpeb4,Zc3h12a,Sirt1,Ifi203,Ifi211,Wdr59,Zfp36,Ifi208,Asns,Ppp1r15a,Cav1,Mndal |
| 2.800e-05 | -10.48 | cell killing | biological process | GO:0001906 | 66 | 15 | 20694 | 1406 |
Pf4,Prdx1,Fcgr1,Bcl2l11,Il18,Ccl2,Trem1,H60b,C3,Rnf19b,Stx11,Ctsc,Serpinb9b,Raet1e,Serpinb9 |
| 2.802e-05 | -10.48 | GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | 145 | 27 | 15632 | 1249 |
Ccr3,Myc,Il6,Kdm5b,Ccnd1,Nod2,Acvrl1,Nr4a1,Stat5a,Ccl12,Jun,Bmp2,Notch1,Tnfaip3,Hif1a,Nrp2,Pdgfb,Htra1,Sirt1,Rictor,Ccl5,Cav1,Kdr,Vegfc,Htr2b,Egr3,Nr4a3 |
| 2.802e-05 | -10.48 | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN | MSigDB lists | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN | 145 | 27 | 15632 | 1249 |
Traf1,Tmtc2,Ddx58,Sgcb,Samhd1,Notch1,Hsph1,Tcf4,Arhgef3,Rsad2,Sdc2,Errfi1,Kif5c,Rnf19b,Acsl1,Phyh,Dusp16,Ppfibp2,Ltbp2,Tor3a,Rims3,Ppm1k,Sap30,Rhou,Oas2,Spint2,Leng9 |
| 2.812e-05 | -10.48 | GTP binding | molecular function | GO:0005525 | 354 | 46 | 20217 | 1400 |
Tgtp1,Rhof,Gbp2b,Arl4a,Rab9,Gbp8,Gbp9,Nkiras1,Rnd3,Gmppb,Irgq,Rap2c,Rhou,Rras2,Iigp1,Mx1,Gem,Samhd1,Rab10,Rhoc,Gna15,Rnd1,Arl5c,Rab20,Tuba4a,Rab21,Ehd1,Ciita,Gbp7,Hcar2,Rhoq,Arf4,Gch1,Rab19,Gtpbp2,Ak4,Rac3,Irgm1,Arl5b,Gbp2,Cgas,Rab32,Mocs1,Ift22,Gbp3,Rhoh |
| 2.814e-05 | -10.48 | GTGCCTT_MIR506 | MSigDB lists | GTGCCTT_MIR506 | 665 | 83 | 15632 | 1249 |
Pde4b,Myadm,Tshz1,Nrp2,Rilpl1,Rab10,Btg2,Arl5b,Gbgt1,G3bp2,Eya4,Smox,Pim1,Phf6,Trib3,Chic2,Rcan1,Fcho2,Nr4a3,Nsmaf,Spire1,Arid5b,Ralgds,Cldnd1,Fmnl2,Abcc4,P4ha2,Plod3,Phldb1,N4bp1,Clmp,Bcl6,Serp1,Nr3c1,Stat3,Oaf,Tbc1d1,Rab11fip1,Rffl,Egr2,Fchsd2,Ccdc86,Fam133b,Rnf135,Gys1,Cd164,Myo10,Tsku,Tor3a,P4ha1,Ednrb,Cav1,Lmo4,Hivep3,Jag1,Rhou,Kpna3,Irf1,Map2k4,Asf1a,Adam19,Stard7,Lhx2,Hivep2,Nr4a1,Rnf114,Flrt3,Bcl2l11,Tmem184b,Vcan,Cpd,Pde5a,Palld,Mapkapk2,Ccnd2,Xrn1,Papss2,Sdc4,Slc16a1,Spred1,Atp2b4,Rbl1,Ahr |
| 2.822e-05 | -10.48 | GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_DN | 186 | 32 | 15632 | 1249 |
Rab19,Tulp3,Agtrap,Ppm1l,Psme1,Daxx,Ripk3,Ifit1,Tnfaip3,D16Ertd472e,Glipr2,Dhx58,Irf4,Slfn8,Dbnl,Gbp9,Gbp4,4930453N24Rik,Spata5l1,Map3k8,Larp1,Nfil3,Vcam1,Rbms1,Cmklr1,Rgs1,Slfn9,Ldlr,Cnp,Rasgrp1,Trim26,H2-Aa |
| 2.822e-05 | -10.48 | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP | MSigDB lists | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP | 186 | 32 | 15632 | 1249 |
Cers6,Rab11fip1,B4galt4,Trip10,Cited2,Itgav,Pik3r5,Enpp4,Hk3,Extl2,Cd80,Coa5,Rab19,Smpdl3b,Tyk2,Stx11,Pdgfb,Rab10,Psme2,Rnaset2a,Tap2,Adap2,Atp6v1d,Arid4a,Slc12a9,Rnaset2b,Gfpt1,Cldnd1,Tlr2,Frmd4a,Casp7,Il13ra1 |
| 2.822e-05 | -10.48 | GSE7852_LN_VS_THYMUS_TCONV_UP | MSigDB lists | GSE7852_LN_VS_THYMUS_TCONV_UP | 186 | 32 | 15632 | 1249 |
Gpc1,Rbm43,Irak3,Gbp3,Bcl2a1d,Cd200r4,Bcl2a1b,Apobec3,Casp1,Cst7,Crbn,Ldlr,Rgs1,Bcl2a1a,Notch2,Dnajb2,Socs3,Oas1g,Ttc39b,Serpinb9,Spata5l1,Nr4a3,Odc1,Rcn1,Plscr1,Oas1a,Ccl5,Slc12a9,Casp4,Atp6v1d,Adap2,Tnfsf14 |
| 2.838e-05 | -10.47 | DASU_IL6_SIGNALING_UP | MSigDB lists | DASU_IL6_SIGNALING_UP | 57 | 15 | 15632 | 1249 |
Cxcl2,Tapbp,Maff,Zfp36,Htra1,Il6,Pdpn,Gem,Ccl12,Sod2,Agrn,Rgl1,Ptges,Serpinb2,Ier3 |
| 2.865e-05 | -10.46 | growth factor receptor binding | molecular function | GO:0070851 | 148 | 25 | 20217 | 1400 |
Lyn,Il6,Il12rb1,Myd88,Src,Pdgfc,Vegfc,Pdgfrb,Ptprj,Jak2,Cd300lf,Tlr9,Il10,Flrt3,Snx2,Csf3,Flrt2,Arf4,Pdgfb,Plscr1,Il1a,Il1rn,Il1b,Itga5,Angpt1 |
| 2.891e-05 | -10.45 | Interleukin-1 processing | REACTOME pathways | R-MMU-448706 | 6 | 5 | 8608 | 757 |
Nfkb1,Nfkb2,Casp1,Il1b,Il18 |
| 2.924e-05 | -10.44 | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | REACTOME pathways | R-MMU-168643 | 41 | 13 | 8608 | 757 |
Nod1,Irak2,Mefv,Aim2,Tnfaip3,Ripk2,Casp8,Nod2,Txn1,Ikbkg,Nlrp3,Casp1,Tab2 |
| 2.931e-05 | -10.44 | GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 178 | 31 | 15632 | 1249 |
Ripk2,Ifi35,Xkr8,Tapbpl,Nr4a3,Ms4a6d,Irf1,Mob3b,4930453N24Rik,Inpp1,Ikbkg,Dcun1d3,Ppp1r15b,Ifit1bl2,Gpr132,Leng9,Prdm1,1600014C10Rik,Rbm43,Zbp1,Herc3,Nod1,Crlf3,Tnfrsf14,Spn,Cnn2,Ifit1bl1,Psmb9,Gpr18,D1Ertd622e,Mafk |
| 2.931e-05 | -10.44 | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDC_DN | 178 | 31 | 15632 | 1249 |
Kdr,Tax1bp1,Rgs1,Cmpk2,Ptgir,Fndc3a,Denr,Socs3,Ptk2,Serpinb9,Gpr85,Rasgrp1,Igsf9,Nampt,Rrs1,Casp8,Ubr4,Cd274,Lcp2,Cacybp,Il15,Hvcn1,Apaf1,Nupr1,Abr,Rnf135,Ifih1,Il18bp,Cox17,Tnf,Gadd45b |
| 2.931e-05 | -10.44 | GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_DN | MSigDB lists | GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_DN | 178 | 31 | 15632 | 1249 |
Itpr1,Dock10,Ccng2,Dusp4,Nod2,Phlpp1,Myc,Rab21,Slfn8,Spry2,Pikfyve,Il4ra,Ubash3b,Tab2,Hvcn1,Traf5,Gnb4,Arid4a,Ampd3,Zc3h7a,Tlr2,Ier3,Ptk2,Snn,Prkar2b,Esd,Nfkb2,Slfn9,Inpp1,Whamm,Jak2 |
| 2.935e-05 | -10.44 | Fc epsilon receptor (FCERI) signaling | REACTOME pathways | R-MMU-2454202 | 317 | 50 | 8608 | 757 |
Psme2b,Angpt1,Lyn,Src,Phlpp2,Spred1,Nfkb1,Map2k4,Ppp2r1b,Syk,Nr4a1,Phlpp1,Psmd10,Malt1,Ikbkg,Psmb10,Jun,Lcp2,Pik3cd,Psmb9,Fos,Rictor,Tab2,Ppp2r5a,Irs2,Kitl,Cdkn1a,Pdgfb,Cd86,Map2k1,Jak2,Il2rg,Nfkbia,Ksr1,Pdgfrb,Psma6,Trib3,Cd80,Psme2,Psmb8,Ier3,Met,Ptk2,Mdm2,Dusp5,Psme1,Dusp6,Psmb6,Rapgef2,Rasgrp1 |
| 2.951e-05 | -10.43 | CCR5 chemokine receptor binding | molecular function | GO:0031730 | 7 | 5 | 20217 | 1400 |
Ccl5,Nes,Stat3,Ccl4,Stat1 |
| 2.951e-05 | -10.43 | Toll-like receptor binding | molecular function | GO:0035325 | 15 | 7 | 20217 | 1400 |
S100a8,Tlr2,Syk,Tlr6,Tlr1,Saa3,Myd88 |
| 2.955e-05 | -10.43 | GO_GOLGI_APPARATUS | MSigDB lists | GO_GOLGI_APPARATUS | 1304 | 144 | 15632 | 1249 |
St3gal1,Naa25,Tlr3,Psmb6,Stip1,Vcam1,Sec24a,Gcnt2,Ppp1r15a,Fzd5,Golga3,Map2k1,Vps54,H2-Eb1,Gja1,Mmp13,Ext1,Rab10,Gbgt1,H2-Aa,Slc39a13,Cd74,Gbp3,Plk3,Parp10,Pdgfc,Lipg,Cd14,H2-Q6,Mtus1,Mgat1,Tpst1,Glipr2,Nfkbie,B3gnt5,Rsad2,Rab21,Rnf24,Mppe1,Rab20,Lyn,Tlr9,Itga5,Pmepa1,Whamm,Notch2,Arf4,Adam19,Ust,Gbp2b,Ldlr,Cav1,Lap3,Mmd,Stx6,Rhou,Sdc1,Cyth3,Pikfyve,Slc30a1,Nck1,Zc3hav1,Atp11b,Sdc4,Il15,F10,Lpcat2,Gpc1,B4galt4,Trip10,Vcan,Ap3b1,Optn,Ift57,Cpd,Pla2g4a,Ctsc,Mmp14,Aftph,Grina,Chic2,Tgfbi,Tapbpl,H2-Ab1,Cd55,Fndc3a,Scyl2,Il15ra,Sec24b,Myo1b,Ascc3,Stx11,Inpp5b,Pdgfb,Tlr1,Agtrap,St3gal6,H2-Q7,Apba1,Notch1,Clcn5,Mdfic,Hck,Gbp2,Acpp,Dse,Slc2a1,Ppp6r1,Tapbp,Fut8,Dbnl,Rab9,Rffl,Rhoq,Tlr2,Ap3m2,Fam20c,Kdr,Ptch1,Clic5,Slc39a14,Rasgrp1,Bcl9,Akt3,Plscr1,St3gal5,Plagl1,Sgms2,Prnp,Xrn1,Tlr6,St3gal3,Vcpip1,Rnd3,Pde3b,Rab32,H2-Q4,Agrn,Chst11,Sdc2,Cxcl14,Kcnj2,Irgm2,Prkce |
| 2.961e-05 | -10.43 | regulation of blood vessel endothelial cell migration | biological process | GO:0043535 | 90 | 18 | 20694 | 1406 |
Hmox1,Rgcc,Ptgs2,Stat5a,Hif1a,Kdr,Cd40,Pdgfb,Vegfc,Spred1,Mecp2,Notch1,Akt3,Sirt1,Angpt1,Acvrl1,Plk2,Thbs1 |
| 2.980e-05 | -10.42 | extrinsic apoptotic signaling pathway in absence of ligand | biological process | GO:0097192 | 38 | 11 | 20694 | 1406 |
Bcl2l11,Bcl2a1a,Casp2,Lcn2,Il1b,Bcl2a1b,Itgav,Bcl2a1d,Kitl,Fas,Il1a |
| 2.980e-05 | -10.42 | signal transduction in absence of ligand | biological process | GO:0038034 | 38 | 11 | 20694 | 1406 |
Casp2,Bcl2a1d,Lcn2,Kitl,Fas,Il1a,Il1b,Bcl2a1b,Bcl2l11,Bcl2a1a,Itgav |
| 2.980e-05 | -10.42 | CD4-positive, alpha-beta T cell differentiation | biological process | GO:0043367 | 38 | 11 | 20694 | 1406 |
Il12b,Relb,Rsad2,Sema4a,Batf,Stat3,Irf4,Gadd45g,Ptger4,Spn,Il6 |
| 3.004e-05 | -10.41 | regulation of cold-induced thermogenesis | biological process | GO:0120161 | 142 | 24 | 20694 | 1406 |
Adrb2,Lcn2,Dio2,Syk,Acsl1,Cmklr1,Plcl2,Gadd45g,Plac8,Il18,Lnpep,Irf4,Pdgfc,Notch1,Tle3,Nr1h3,Kdm6b,Igf1r,Dync1h1,Jak2,Gja1,Il4ra,Cav1,Il15 |
| 3.025e-05 | -10.41 | TCGA_GLIOBLASTOMA_COPY_NUMBER_DN | MSigDB lists | TCGA_GLIOBLASTOMA_COPY_NUMBER_DN | 33 | 11 | 15632 | 1249 |
Spryd7,Phf11b,Spsb1,Eno1,Setdb2,Fndc3a,Kpna3,Trim13,Phf11d,Phf11a,Phf11c |
| 3.025e-05 | -10.41 | GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | 33 | 11 | 15632 | 1249 |
Rffl,Traf2,Serpine1,Casp8,Rnf34,Cflar,Tnfsf10,Tnfaip3,Fas,Hmox1,Icam1 |
| 3.025e-05 | -10.41 | PID_IL1_PATHWAY | MSigDB lists | PID_IL1_PATHWAY | 33 | 11 | 15632 | 1249 |
Irak3,Il1b,Il1rn,Myd88,Tab2,Il1a,Jun,Ikbkg,Sqstm1,Nfkb1,Casp1 |
| 3.026e-05 | -10.41 | GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_DN | MSigDB lists | GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_DN | 170 | 30 | 15632 | 1249 |
Usp18,Sphk1,H2-Q7,Ddx60,Slfn5,Zbp1,Rbm43,Adar,H2-Q6,Oas3,Eif2ak2,H2-Q4,Tgs1,Dusp2,Ifi44,Ifi35,Herc6,Oasl1,Itga5,Epsti1,Actb,Ccl4,Itgal,Ogfr,Rgl1,Brd2,Ikbkg,Oas2,Syne2,Uba7 |
| 3.026e-05 | -10.41 | GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | 170 | 30 | 15632 | 1249 |
Rnf34,Hinfp,Klf7,Egr1,Tlr6,Fas,Pnp2,Aftph,Egr2,Edn1,D1Ertd622e,Ap3b1,Treml2,Klf6,Serpinb2,Tax1bp1,Rbms1,Il1b,Egr3,Tlr3,Tlr2,Acsl1,Trib1,Ptgs2,Tlr1,Fabp7,Btg2,Ccr1,Rgl1,Tnfsf14 |
| 3.039e-05 | -10.40 | African trypanosomiasis | KEGG pathways | ko05143 | 35 | 12 | 7931 | 713 |
Il6,Fas,Vcam1,Myd88,Icam1,Sele,Tnf,Il12b,Il1b,Tlr9,Il10,Il18 |
| 3.039e-05 | -10.40 | African trypanosomiasis | KEGG pathways | mmu05143 | 35 | 12 | 7931 | 713 |
Il18,Tlr9,Sele,Il10,Tnf,Icam1,Il1b,Il12b,Myd88,Il6,Fas,Vcam1 |
| 3.044e-05 | -10.40 | regulation of nervous system development | biological process | GO:0051960 | 1068 | 107 | 20694 | 1406 |
Mark2,Cst7,Agrn,Bcl6,Sec24b,Ednrb,Kat2b,Zhx2,Ccl5,Igf1r,Mosmo,Nlgn2,Mycl,Katna1,Etv5,Nck1,Met,Fzd1,Tcf4,P2ry12,P2ry2,Cx3cl1,Tnf,Zswim4,Kdr,Fubp1,Il15ra,Hmga2,Il1b,Mdm2,Sirt1,Kremen1,Lyn,Cav1,Clcf1,Cdk5r1,Pbx1,Dbnl,Itpr1,Sema4a,Adgrl2,Ctsc,Bmp2,Cd38,Rapgef2,Plk2,Lhx2,Cflar,Mmd,Jag1,Kdm4a,Il6,Cyfip1,Hif1a,Casz1,Ptk2,Dync1i2,Prag1,Rac3,Zeb1,Myc,Flrt2,Fas,Csf1,Lrp8,Ifrd1,D16Ertd472e,Spen,Sema4c,Ntng2,Sipa1l1,Stap1,Rab21,Cx3cr1,Sdc2,Ust,Hdac1,Ehd1,Tspo,Tulp3,Vegfc,Mov10,Mecp2,Kif3c,Gfi1,Rgs14,Notch1,Scarf1,Tnfrsf1b,Tlr2,Crkl,Rap1gap2,Sphk1,Flrt3,Hap1,Map2k1,Eif4g2,Ldlr,Nr3c1,Sema3c,Map4k4,Stat3,Lrp4,Lpar1,Mul1,Lif,Scn1b |
| 3.083e-05 | -10.39 | Antigen processing-Cross presentation | REACTOME pathways | R-MMU-1236975 | 98 | 22 | 8608 | 757 |
H2-M2,Tap1,Psmd10,H2-Q4,Psme2b,Psme2,Psma6,Tap2,Psmb10,Tapbp,H2-Q6,Psmb8,H2-T24,H2-T10,Psme1,Psmb6,H2-T22,Lnpep,Itgav,H2-Q7,Psmb9,Fcgr1 |
| 3.101e-05 | -10.38 | HUANG_GATA2_TARGETS_DN | MSigDB lists | HUANG_GATA2_TARGETS_DN | 64 | 16 | 15632 | 1249 |
Hk2,Pdgfb,Phlda1,Daam1,Asns,Slc2a1,Rabgef1,Mthfd1l,Plagl2,Pf4,Actb,Pbx1,Mthfd2,Jmjd6,St3gal6,Egr1 |
| 3.102e-05 | -10.38 | GSE32901_NAIVE_VS_TH17_ENRICHED_CD4_TCELL_DN | MSigDB lists | GSE32901_NAIVE_VS_TH17_ENRICHED_CD4_TCELL_DN | 162 | 29 | 15632 | 1249 |
Cd69,Hk2,Med13,Casp8,Samsn1,Plk2,Lnpep,Cdkn1a,H3f3b,Rgs1,Hcls1,Arf4,Phf6,Phyh,Fcho2,Slc43a3,Dgkh,Mtmr14,Ythdf1,Cdyl2,Hdac1,Tgs1,Tcf4,Rhoc,Cd38,Klf7,Sla,Kmo,Nfkbiz |
| 3.102e-05 | -10.38 | GSE37532_WT_VS_PPARG_KO_LN_TREG_UP | MSigDB lists | GSE37532_WT_VS_PPARG_KO_LN_TREG_UP | 162 | 29 | 15632 | 1249 |
Pml,Egr1,Mxd1,Irf2,P2ry14,Irs2,Trim13,Cd80,Fbrsl1,Rbms2,Ahr,Plagl2,Pik3r5,Ifit1bl1,Axl,Bcl6,Cited2,Ptprj,Kdm6b,Arid5b,Grina,Abcc4,Ifit1bl2,Jarid2,Casp8,Zfp36,Atxn7l1,Pou2f2,Etv6 |
| 3.102e-05 | -10.38 | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_UP | 162 | 29 | 15632 | 1249 |
Marco,Pid1,Card6,Ahrr,Slc31a2,Stx6,Met,Bst1,Htra1,Arl5b,Procr,Nsmaf,Acvr1b,Clec5a,Dgkh,Plaur,Bcl2a1a,Arhgef3,Bcl2a1b,Bcl2a1d,Gpr68,Kremen1,Pdpn,Pnp2,Irs2,Trim13,Tlr6,Fcgr1,Clec4e |
| 3.117e-05 | -10.38 | GNF2_MCL1 | MSigDB lists | GNF2_MCL1 | 51 | 14 | 15632 | 1249 |
Myd88,Hck,Samhd1,Ier2,Sell,Tlr2,Igsf6,Rab11fip1,Stx11,Nod2,Casp1,Ccr1,Junb,Cd302 |
| 3.137e-05 | -10.37 | LEE_BMP2_TARGETS_UP | MSigDB lists | LEE_BMP2_TARGETS_UP | 667 | 83 | 15632 | 1249 |
Dtx3l,Ifih1,Gbp3,Usp18,Nupr1,Irf2,Gbp2,Hvcn1,Rgs3,Gda,Cd14,Lipg,Traf5,Apobec3,Casp1,Phldb1,Lipe,Tapbp,C1ra,Ccng2,Cebpd,Fgl2,Rbpms,Itgb8,Cp,Slc39a4,Sat1,Il18,Grina,Dio2,Plat,Slc7a2,Tap2,Cnp,Lad1,Sesn3,Plek,Slc31a2,4930523C07Rik,Uba7,Spint2,Dgka,Degs2,Tmem26,Nmi,Ddit4,P2ry14,Sgms2,Tmtc2,Col18a1,Tmem176b,Slc48a1,Sdc4,Jun,Agrn,Bcl2l11,Ppp1r14b,Ezr,Gsdmd,Adhfe1,Pde5a,Pdpn,Abcb1a,Rcsd1,Ier3,Rab20,Sema4a,Cacnb3,Fam20c,Cd82,Jak2,Fam102b,Lcn2,Gbp7,Hdc,Hk1,Psmb8,Tmem176a,Jag1,Plscr1,Ampd3,Htra1,Rtn2 |
| 3.149e-05 | -10.37 | GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP | MSigDB lists | GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP | 187 | 32 | 15632 | 1249 |
4930523C07Rik,Asah2,Rnaset2a,Btg2,Stat4,Hivep3,Mtmr14,Grina,Mppe1,Gtpbp2,Thbs1,Rnaset2b,Sp110,Fam43a,Apobec3,Psmb9,Jun,Ctsc,Pde1b,Ifi44,Glipr2,Irf2,Nfkbiz,Mxd1,Tlr6,Rab19,Irs2,1600014C10Rik,Cd38,Ncoa7,Slc28a2,Zc3hav1 |
| 3.149e-05 | -10.37 | GSE24142_DN2_VS_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_DN | 187 | 32 | 15632 | 1249 |
Irf4,Minpp1,Egr2,Peli1,Ppp2r5a,Errfi1,Gsr,Axl,Itpr1,Ets2,Tpst1,Rras2,Slc16a1,Notch1,Cd164,Relb,Pgs1,Egr1,Tulp3,Traf1,Ddit4,Btg2,Phlda1,Degs2,Rnf19a,Bst1,Dgka,Slc29a3,Gfi1,Pmepa1,Cpeb4,Socs3 |
| 3.149e-05 | -10.37 | GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_UP | 187 | 32 | 15632 | 1249 |
Cmpk2,Rnaset2b,Slfn3,Vcam1,Rnf145,Casp7,Dgka,Psme2,Timeless,Isg20,Tap2,Mov10,Slfn4,Klf2,Lgals9,Rnaset2a,Nfkb1,Dusp6,Tap1,Ifih1,Spata13,Ccnd2,Tlr6,Hhex,Psme1,Marcksl1,Tapbp,Hdac1,Nat2,Bcl2l11,Ifnar1,Parp8 |
| 3.155e-05 | -10.36 | GSE16385_UNTREATED_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_UNTREATED_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN | 154 | 28 | 15632 | 1249 |
Extl2,Batf,Cd83,Gng11,Slamf7,Rars,Malt1,Magohb,Ccnd1,Slc39a4,Homer1,Lacc1,5430427O19Rik,Fscn1,4930453N24Rik,Dnajb4,Ier3,Cxcl10,Adrb2,Ptk2,Ripk2,Cxcl2,Ppp4r2,Cnp,Atp6v1d,Pik3r6,Slc12a9,Nampt |
| 3.173e-05 | -10.36 | GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_UP | 138 | 26 | 15632 | 1249 |
Oaf,Slc15a3,Tnfsf8,Cish,Hdac1,Dse,Cd34,Ahr,Ppfibp1,Nek6,Spred3,Jag1,Stx6,Il18rap,Egln3,Ccl5,Tnfsf14,Zc3h12c,Cacybp,Plod2,Fubp1,Dcbld2,Ebi3,Atp10a,Mafg,Cxcl10 |
| 3.238e-05 | -10.34 | MODULE_165 | MSigDB lists | MODULE_165 | 71 | 17 | 15632 | 1249 |
Bcl2a1b,Plek,Csf3r,Cited2,Ets2,Irf8,Lcp2,Tlr1,Bcl2a1d,Pla2g7,Rhoh,Lyn,Cxcl10,Ptgs2,Bcl2a1a,Hck,Hk3 |
| 3.238e-05 | -10.34 | sequence-specific DNA binding | molecular function | GO:0043565 | 1134 | 114 | 20217 | 1400 |
Cebpd,Pou3f1,Ifi211,Hdac1,Lmo4,Mafk,Irf7,Prdm1,Mcm9,Fosb,Pbx1,Nfkb1,Irf1,Hivep2,Ahr,Stat2,Stat1,Etv3,Eno1,Mcm6,Zbtb5,Rfx5,Myc,Maff,Kdm6b,Stat3,Ifi205,Tcf4,Hhex,Stat5a,Fubp1,Irf8,Hmga2,Spic,Ikzf1,Snapc1,Ifi203,Rel,Egr2,Hinfp,Relb,Irf4,Etv5,Ier2,Max,Nr1h3,Nr4a1,Nlrc5,Sirt1,Tfec,Smg7,Bcor,Plagl2,Sp140,Prdm9,Etv6,Mecp2,Kat2b,Egr1,Atf3,Notch1,Irf2,Tlr9,Foxp4,Mcm10,Mndal,Klf6,Hlx,Arid5a,Klf3,Tal2,Ifi209,Plagl1,Zfp281,Nr3c1,Klf8,Junb,Klf7,Egr3,Nlrp3,Jun,Nfil3,Ifi204,Ifi213,Csrnp1,Phf6,Ets2,Nfxl1,Lhx2,Pou2f2,Batf,Nfkb2,Hmga1,Pcgf5,Ifi207,Ifi208,Batf2,Hif1a,Stat4,Jarid2,Bcl6,H3f3b,Aebp2,Arid5b,Jdp2,Mafg,Dach1,Mycl,Ifi214,Nr4a3,Kdm5b,Fos,Mxd1,Zeb1 |
| 3.241e-05 | -10.34 | regulation of protein autophosphorylation | biological process | GO:0031952 | 45 | 12 | 20694 | 1406 |
Rap2c,Src,Pdgfc,Tnks1bp1,Mvp,Cav1,Jun,Ppp2r5a,Errfi1,Vegfc,Pdgfb,Syk |
| 3.241e-05 | -10.34 | CD4-positive, alpha-beta T cell activation | biological process | GO:0035710 | 45 | 12 | 20694 | 1406 |
Relb,Rsad2,Ptger4,Il6,Tnfsf4,Il12b,Sema4a,Stat3,Batf,Irf4,Gadd45g,Spn |
| 3.244e-05 | -10.34 | endosome | cellular component | GO:0005768 | 829 | 87 | 20747 | 1409 |
Kdr,Ifitm1,Rabgef1,Clcn5,Arrdc4,Stoml1,Treml4,Atp11a,Carmil1,Dbnl,Sphk1,Samd9l,Snx10,Snx2,Ociad1,Atp11b,Sla,Vcam1,Fzd5,Mitd1,Micall2,Rab32,Lipg,Rffl,Fchsd2,Ehd1,Lpar1,Adrb2,Acpp,Scyl2,Fcgr2b,Map2k1,Flt1,Tnf,Inpp5b,Wdfy1,Rap2c,Zc3hav1,Mmp14,Mcoln2,Pmepa1,Cd164,Gpc1,Stx6,Optn,Rapgef2,Sgk3,Nox1,Rab10,Slc31a2,Cd274,Tlr9,Myo1b,Slc30a4,H2-Ab1,Ifnar1,Ezr,Tlr3,Src,Cav1,Slc48a1,P2ry2,Rab11fip1,Dgkh,Rab21,Irgm1,Dtx3l,Slc29a3,H2-Eb1,Znrf1,Plekhf2,Psd,Dennd6b,Cd74,Ccr3,Chmp4b,Calcrl,Pml,Gja1,Sqstm1,Pikfyve,Cst7,Rab20,Slc31a1,Ldlr,Rab9,Slc39a4 |
| 3.246e-05 | -10.34 | negative regulation of oxidative stress-induced cell death | biological process | GO:1903202 | 52 | 13 | 20694 | 1406 |
Il10,Glrx,Txn1,Hsph1,Hk3,Sirt1,Met,Fzd1,Ncoa7,Slc7a11,Sod2,Nr4a3,Hif1a |
| 3.246e-05 | -10.34 | regulation of interferon-beta production | biological process | GO:0032648 | 52 | 13 | 20694 | 1406 |
Rnf135,Tlr3,Ifih1,Ifnar1,Irf7,Relb,Ddx58,Tlr2,Tlr9,Irf1,Rel,Zc3hav1,Nmi |
| 3.247e-05 | -10.34 | positive regulation of cell cycle | biological process | GO:0045787 | 352 | 45 | 20694 | 1406 |
Sphk1,Crlf3,Nr4a3,Psmd10,Prkce,Cdk5r1,Ccnd1,Pim1,Pbx1,Mdm2,Gpsm2,Il1b,Pdgfb,Ccnd2,Tmod3,Smc5,Prdm9,Bcl2l11,Src,Asns,Casp2,Ccne1,Igf1r,Hspa2,Ube2e2,Ankrd17,Dync1h1,Trim21,Phip,Edn1,Rgcc,Pkp4,Myc,Pdgfrb,Cited2,Mecp2,Cenpj,Cenpe,Stat5a,Il1a,Tnf,Met,Pml,Il10,Cdkn1a |
| 3.253e-05 | -10.33 | tissue remodeling | biological process | GO:0048771 | 116 | 21 | 20694 | 1406 |
Stat5a,Cav1,Notch2,Jag1,Il1a,Ahr,Lif,Hif1a,Timp1,Gja1,Axl,Snx10,Mmp14,Adrb2,Sema3c,Itga4,Mdm2,Acp5,Src,Mmp9,Acvrl1 |
| 3.253e-05 | -10.33 | myeloid leukocyte differentiation | biological process | GO:0002573 | 116 | 21 | 20694 | 1406 |
Sirt1,Src,Junb,Csf3,Batf,Irf4,Tnfsf9,Fam20c,Cd300lf,Hhex,Snx10,Casp8,Cited2,Il15,Tlr2,Tnf,Batf2,Csf1,Relb,Notch2,Jun |
| 3.259e-05 | -10.33 | positive regulation of macrophage migration | biological process | GO:1905523 | 26 | 9 | 20694 | 1406 |
Mmp14,P2ry12,Csf1,Ccl5,Ptprj,Cx3cl1,Thbs1,Ccl2,Cmklr1 |
| 3.279e-05 | -10.33 | GSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_UP | MSigDB lists | GSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_UP | 179 | 31 | 15632 | 1249 |
Pdss1,Timeless,Slc2a6,AA467197,Myadm,Txn1,Jarid2,Plod2,Lmo4,Gem,Irf8,Thbs1,Osbpl3,Esd,Smc5,Sema4c,Dram1,Lyn,Mob3b,Slc15a3,Cp,Ankrd24,Cebpd,Mlkl,Cers6,Mdm2,Txnrd1,Trim36,Slamf7,Col4a2,Ahr |
| 3.279e-05 | -10.33 | GSE3982_DC_VS_BCELL_UP | MSigDB lists | GSE3982_DC_VS_BCELL_UP | 179 | 31 | 15632 | 1249 |
Adora2b,Rcan1,Clec5a,Slc31a1,Fam162a,Nfil3,Cdkn1a,Fscn1,Cd86,Fzd5,Slc31a2,Bst1,Ccrl2,Ppp2r3a,Egln3,Alas1,Nlrp3,Atf3,Palld,Pdgfc,Hk3,Samhd1,Myo10,Cd83,Pilra,Plau,Sdc4,Spsb1,P4ha2,Dhrs9,Spry2 |
| 3.279e-05 | -10.33 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 179 | 31 | 15632 | 1249 |
Cnn3,Isg20,Trim21,Ddit4,Ext1,Rnf14,Dusp6,Birc3,Jarid2,Rnaset2a,Ikbke,Ldlr,Znrf1,Rnaset2b,Igf1r,Dusp16,Gpd2,Egr2,Hdac1,Spsb1,Birc2,Tcf4,Ets2,Ahr,Rab3ip,Ifit1,Klf7,Tlr6,Slc30a4,Cyth3,Zfp281 |
| 3.279e-05 | -10.33 | GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP | 179 | 31 | 15632 | 1249 |
Map4k4,Fosb,Pid1,Klf2,Cd86,Zfp36,Zscan29,Dck,Casp7,Mtdh,Il18,Ddx4,Zcchc2,Clcf1,Orai2,Abcc4,Ifnar1,Klf3,Klf6,Gramd1a,Ezr,Dpy19l1,Jun,Mtus1,Rtp4,Pttg1,Slc25a25,Il15,Mcmbp,Foxp4,Mark2 |
| 3.279e-05 | -10.33 | GSE26351_UNSTIM_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP | MSigDB lists | GSE26351_UNSTIM_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP | 179 | 31 | 15632 | 1249 |
Arl4a,Ccl22,Palld,Magohb,Samhd1,Cd40,Arhgef3,Mrpl52,Hspa2,Cers6,Cox17,Hdac1,Dusp2,Ly75,Ubtd2,Ppp2r5a,Rab21,Il18,Mppe1,Mob3b,Slamf8,Dck,Ppa1,Dr1,Med21,Abtb2,Tyk2,Casp2,Timeless,Pdlim7,Akt3 |
| 3.279e-05 | -10.33 | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_DN | MSigDB lists | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_DN | 179 | 31 | 15632 | 1249 |
Plek,Stat4,Ier3,Frmd4a,Sema4a,Pim2,Ap3m2,Rcl1,Igf2bp2,Epsti1,Adam19,Clcf1,Zyx,Cd302,Apobec3,Cst7,Ehd1,Plac8,Dock10,Gpr68,B3gnt5,Glipr2,Rhoq,Ctsc,Phgdh,Rab19,Tlr6,Mcoln2,Psme1,Slc16a1,Rras2 |
| 3.285e-05 | -10.32 | negative regulation of cell motility | biological process | GO:2000146 | 279 | 38 | 20694 | 1406 |
Stap1,Timp1,Spint2,Clic4,Rabgef1,Cd200,Gpr18,Sinhcaf,Fas,Rgcc,Trib1,Serpine1,Svbp,Il1rn,Notch1,Ptk2,Dusp1,Mecp2,Ptger4,Pdgfb,Spred1,Cited2,Cnn2,Cx3cl1,Jag1,Lrch1,Abr,Acvrl1,Stat3,Slamf8,Thbs1,Evl,Ccl12,Rap2c,Ptprj,Dach1,Cx3cr1,D1Ertd622e |
| 3.285e-05 | -10.32 | positive regulation of interferon-beta production | biological process | GO:0032728 | 32 | 10 | 20694 | 1406 |
Zc3hav1,Irf7,Tlr2,Ddx58,Tlr9,Tlr3,Ifih1,Rnf135,Ifnar1,Irf1 |
| 3.285e-05 | -10.32 | positive regulation of interleukin-2 production | biological process | GO:0032743 | 32 | 10 | 20694 | 1406 |
Il1b,Il1a,Cd83,Tnfsf4,Ripk2,Stat5a,Malt1,Irf4,Traf2,Pde4b |
| 3.285e-05 | -10.32 | B cell homeostasis | biological process | GO:0001782 | 32 | 10 | 20694 | 1406 |
Dock10,Ahr,Lyn,Tnfaip3,Bcl2a1a,Ikbkg,Bcl2l11,Hif1a,Casp3,Pik3cd |
| 3.285e-05 | -10.32 | alpha-beta T cell activation involved in immune response | biological process | GO:0002287 | 32 | 10 | 20694 | 1406 |
Spn,Ptger4,Gadd45g,Il6,Batf,Stat3,Irf4,Sema4a,Relb,Il12b |
| 3.288e-05 | -10.32 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | 39 | 12 | 15632 | 1249 |
Cav1,Ptpn2,Mul1,Nr1h3,Rabgef1,Nlrc5,Ccl5,Irak3,Il1rn,Stap1,Adar,Rffl |
| 3.292e-05 | -10.32 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN | 45 | 13 | 15632 | 1249 |
Tmem176b,Fas,C3,Ptgs2,Lox,Vcam1,Ltbp2,Fos,Tnc,Stat3,Zfp36,Slpi,Tmem176a |
| 3.292e-05 | -10.32 | PID_NFAT_TFPATHWAY | MSigDB lists | PID_NFAT_TFPATHWAY | 45 | 13 | 15632 | 1249 |
Ptgs2,Fos,Jun,Egr3,Junb,Tnf,Egr1,Dgka,Irf4,Casp3,Ikzf1,Gbp2b,Egr2 |
| 3.292e-05 | -10.32 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 | 45 | 13 | 15632 | 1249 |
Nfil3,Wdr43,Myd88,Mthfd2,Slco3a1,Etnk1,Hk2,Fzd1,Myc,Hopx,P4ha2,Pdk3,Hsph1 |
| 3.293e-05 | -10.32 | GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 749 | 91 | 15632 | 1249 |
Gpr68,Hdac1,Mecp2,Stat3,Bcl6,Ankrd17,Tnf,Pbx1,Sav1,Tulp3,Cd74,Inhba,Rapgef2,Vasn,Serpine1,Hopx,Gja1,Ccr1,Il1b,Il18,Trib3,Tlr3,Ifnb1,Ifrd1,Stap1,Katna1,Bnip3,Ptpn2,Itgav,Plac8,Tspo,Col4a2,Nr1h3,Mul1,Cdk5r1,Ubash3b,Bcor,Tmem176b,Tmem176a,Rap1gap2,Zeb1,Cav1,Sema3c,Jdp2,Ednrb,Lyn,Lpar1,Trib1,Sema4c,Ptk2,Acvrl1,Ccnd1,Timp1,P2ry12,Lrp4,Daxx,Notch1,Bmp2,Hif1a,Pml,Lif,Hlx,Hhex,Nfkbid,Pdgfb,Cd86,Plk2,Pf4,Zhx2,Thbs1,Cxcl10,Ptger4,Cxcl14,Il6,Myc,Ccl12,Cx3cr1,Nfkbia,Pde3b,Il4ra,Abr,Jag1,Sirt1,Ptch1,Gfi1,Cflar,Adrb2,Sema4a,Irf1,Stat1,Tnfsf4 |
| 3.298e-05 | -10.32 | GO_REGULATION_OF_CYTOPLASMIC_TRANSPORT | MSigDB lists | GO_REGULATION_OF_CYTOPLASMIC_TRANSPORT | 432 | 59 | 15632 | 1249 |
Fzd5,Map2k1,Txn1,Csf3,G3bp2,Hap1,Fzd1,Ptgs2,Il12b,Cxcl10,Il18,Tlr3,Zc3h12a,Keap1,Il1b,Sec24b,Bambi,Tnf,Src,Rbpms,Nfkbie,Mdm2,Rab21,Micall2,Ddx58,Sphk1,Parp10,Nfkbil1,Rnf139,Pml,Plagl2,Mdfic,Il10,Tnfsf14,Cav1,Rims3,Rnf31,Sirt1,Rhou,Slc9a1,Nfkbib,Tlr2,Lyn,Tlr9,Dyrk2,Stard7,Cdkn1a,Jak2,Hcls1,Psmd10,Nfkbia,Ezr,Prkce,Il6,Ubash3b,Nlrp3,Stxbp1,Angpt1,Prdx1 |
| 3.328e-05 | -10.31 | MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MSigDB lists | MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 998 | 115 | 15632 | 1249 |
Adora2b,Atp10a,Kitl,Fzd5,Eya4,Icosl,Usp18,F11r,Arg2,Ch25h,Prdm1,Prrg4,Asap3,Tsku,Irak3,Mtus1,Cd302,Stat5a,Slc16a3,Rbpms,Glipr2,B3gnt5,Hspa2,Oaf,Rab11fip1,Itga9,Rab20,Mmp25,Lyn,Rcsd1,Egr3,Uaca,Itga5,Lhx2,Col27a1,Sema3c,Plod2,Adap2,Egln3,Rap1gap2,Pstpip2,Trim14,Zfp36,Tifa,Sdc1,Col18a1,Foxp4,Zc3hav1,Sdc4,Trp53i11,Lpcat2,Casz1,Gadd45b,Trim36,Cnn2,Ass1,Dusp4,Pde5a,Parp14,Mmp14,Kcna3,Mob3b,Lox,Ptger4,Zc3h12a,Igf2bp2,Klf2,Lad1,Slc7a2,Slc13a3,Gch1,Adora2a,Hk2,Maff,Hlx,Itga4,Hhex,Ier2,Notch1,Rhoc,Mdfic,Myo10,Cd83,Bmp2,Swap70,Gypc,Ccnd1,Mlkl,Cish,Carhsp1,Ly75,Egr2,Pde1b,Adrb2,Clcf1,Kdr,Irf8,Plekha2,P2ry2,Clic5,Abtb2,Jag1,Htra1,Ppm1l,Il4ra,Atf3,Tap1,Rras2,Map3k6,Flt1,Ezr,Pik3r5,Bcl2l11,Cxcl14,Ikzf1 |
| 3.340e-05 | -10.31 | protein auto-ADP-ribosylation | biological process | GO:0070213 | 11 | 6 | 20694 | 1406 |
Tiparp,Parp3,Parp8,Parp11,Parp12,Parp10 |
| 3.340e-05 | -10.31 | regulation of chronic inflammatory response | biological process | GO:0002676 | 11 | 6 | 20694 | 1406 |
Il10,Tnfaip3,Adora2b,Cx3cr1,Tnf,Pde5a |
| 3.343e-05 | -10.31 | TNFR1-induced NFkappaB signaling pathway | REACTOME pathways | R-MMU-5357956 | 21 | 9 | 8608 | 757 |
Tnf,Birc3,Ikbkg,Tab2,Traf1,Tnfaip3,Birc2,Rnf31,Traf2 |
| 3.358e-05 | -10.30 | GSE6259_33D1_POS_DC_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_33D1_POS_DC_VS_CD8_TCELL_DN | 115 | 23 | 15632 | 1249 |
Dusp1,Aoah,Axl,P2ry12,Arhgef3,Rffl,Minpp1,Ddx60,Gbp3,Traf5,Irak3,Slc28a2,Lcp2,Itgal,Tlr1,Rasgrp1,Kcna3,Bambi,Fam20c,Ikbke,Zcchc2,Cmklr1,Plaur |
| 3.377e-05 | -10.30 | organelle part | cellular component | GO:0044422 | 7403 | 573 | 20747 | 1409 |
Mafk,Cpd,Ccdc86,Snn,Wdr59,Ccdc88b,Bcor,Ankrd17,Zeb1,Cyth3,Jun,Irf1,Tmod3,Oasl2,Dync1i2,P4ha2,Ldlr,Noc4l,Etnk1,Klf2,Cdyl,Magohb,Rbl1,Yju2,Ptges,Cop1,Clcn7,Gm12185,Bcl2a1b,Kdm5b,Pou2f2,Agtrap,Tasor2,Tspo,Pml,Arl5b,Batf,Resf1,Gm5431,Dse,Fos,Gch1,Top3a,Hsph1,1600014C10Rik,Hspa2,Rrs1,Daam1,Tma16,Jak2,Rrbp1,H2-Eb1,Znfx1,Txnrd1,Gbp3,Egr2,Prkce,Sap30,Egr1,Dtx3l,Nxf1,Ciita,Nr4a1,Snapc1,Ch25h,Kdm6b,Stk40,Phf11b,Phf11a,Etv5,Mx1,Fcho2,Sp100,Ctsc,AA467197,Ikzf1,Fosb,Alas1,Ak4,Cdkn1a,Dhrs9,Aff1,Glipr2,Spata13,Psip1,Etv3,Gfi1,Atf3,Pik3r5,Tgtp1,Rmdn3,Optn,Ier2,Tpx2,Rubcnl,P4ha1,Acsl5,Oas1b,Zc3h12a,Ubr4,Jarid2,Cox17,Bbx,Rab19,Zfp281,Map2k1,Myo10,Sik3,Slc37a3,Mapkapk2,Osbpl3,Brd2,Klf6,Intu,Atp6v1d,Tpst1,Phlpp2,Aim2,Tfec,Irf7,Gsdmd,Tra2a,Nmi,Tgtp2,Rai14,Rap1gap2,Slc4a7,Fas,Cited2,Klf3,Nampt,Bcl2a1d,Irf4,Dnajb4,Gbp8,Treml4,Sbds,Nsd3,Fubp1,Cept1,Nes,Samhd1,Cenpj,Irf2,Hap1,Pcgf5,Rab3ip,Plk3,Hspa1b,Parp3,Flnb,Snx2,Plscr1,Uchl1,Setdb2,Abcc4,Rpgrip1l,Ell2,Parp10,Trim21,H2-Q6,Glrx,Tap2,Stxbp1,Tmem67,Iigp1,Mxd1,Clic5,Tlk2,Pf4,Mapkbp1,9930111J21Rik1,Psd,Ifi211,Gm4841,Sqstm1,Pikfyve,Vrk2,H2-Q7,Pdlim7,Gbp2,Ifi203,Tcea1,Serpinb9,Ifi208,Parp9,Ahr,Fndc3a,Ep400,Slc48a1,Psma6,Ccnd1,Cox18,Rnaset2a,Ifi205,Ccnd2,Relb,Sertad3,Cdkn2d,Med13,Hcls1,Palld,Hilpda,Cenpe,Pkp4,Hspa1a,Oasl1,Ass1,Dennd1b,Dpy19l1,Smox,Pigv,Hif1a,Edn1,Lpcat2,Ranbp2,Pmepa1,Phlpp1,Nlrc5,Kmo,Stat5a,Pim1,Rel,Fscn1,Itpkc,Tgfbi,Olr1,Shfl,Hck,Rgs14,Rhoq,N4bp1,Arid4a,Mcm10,Riox2,Rilpl1,Mdm2,Acpp,Traf5,Fut8,Acsl1,Triobp,Kif3c,Tnip1,Ero1l,Nos2,Dnajb2,Trip10,Ahrr,Ptger4,Notch2,Slc9a1,Fchsd2,Slc2a1,Birc3,Aldh1b1,Aebp2,Mcm6,Srgn,Ets2,Rffl,Ednrb,Max,Hivep2,Rac3,Marcks,Golga3,Tuba4a,Atp11a,Sphk1,Hinfp,Cacna1d,Rnf139,Slc25a22,Prdm9,Dusp4,Atp11b,Mtdh,Sec24a,Fgr,Tor1aip1,Ptk2,Malt1,Polr2g,Htr2b,Nfkb1,Gbp2b,Igtp,Mgat1,Rtn1,Junb,Bnip3,Nlrp3,Klf8,Sirt1,Syne2,Il15,Mdn1,Rapgef5,Ifi214,Clic4,Rtn2,Psmb6,Ifi47,Fam111a,Cx3cr1,Dcp2,Armcx6,Tle3,Mpp7,Cnp,Trib3,Wdr43,Chmp4b,Slc25a37,Ppp1r15a,Phlda1,Spry2,Cdk5r1,Ptpn2,Dr1,F830016B08Rik,Kif9,Oas2,Rcl1,Grk3,Rhbdf2,Vps54,Dtx2,Mtus1,Prdx1,Gk,Myadm,Atm,Abr,Atp2b4,Radx,Ikbkg,Hmgn3,Asf1a,Ifi204,Abtb2,Maml2,Slc29a3,Bcorl1,Gbp9,Rgcc,Mefv,Irf8,Phf11c,Myo1b,Prkar2b,Gng12,Plekha5,Slc16a3,Tcf4,Parp11,Upp1,Dync1h1,Jmjd6,Dyrk2,Stap1,Src,Sh3bgrl2,Mark2,Keap1,Pde4b,Trim14,Ric1,Clmp,Traf2,D1Ertd622e,Ppp2r5a,Rap2c,Slc25a12,Nr1h3,Homer1,Hdac1,Kif5c,Sema4c,Bcl2a1a,Mx2,Smg7,Phf6,Ift22,Tulp3,Pcx,Prpf4,Pdk3,Crbn,Sco1,Mul1,Asap3,Casz1,Gpsm2,Aftph,Nr3c1,Nfkbiz,Cutc,Higd1a,Ifi207,Ciapin1,Sp140,Plod3,Cebpd,Myc,Gramd1a,Mndal,Rab32,Arid5a,Tnks1bp1,Mosmo,Itpr1,Eef1e1,Nlgn2,Taf4b,Ifi209,Ift57,Cnn2,Ppp4r2,Mecp2,Cep350,Cycs,Dst,Rgs3,Zyx,Snx10,Cd38,Crkl,Rnf34,Tmtc2,Sgms2,Spire1,Actb,Arl5c,Casp8,Mrpl52,Mdfic,Plekhg1,Bcl9,Slc15a3,Psme2,Rab9,H2-Q4,Ccne1,Rhoc,Pbx1,Sinhcaf,Ldha,Kdm4a,Gja1,Cgas,Tmem178,Lap3,Oas3,Pnpt1,Pfkfb3,H3f3b,Slc30a1,Gm4951,Hmga2,Mppe1,Dock4,Ppm1k,Lnpk,Slc44a1,Plekhn1,Rab21,Irgm1,Cep85l,Rsad2,Csrp1,Cav1,Kat2b,Rbbp8,Ppp1r12b,Ago3,Tut7,Stat3,Etv6,Pgap2,Hk1,Sass6,Trim13,Plpp3,Adora2a,Agpat4,Cd274,Plk2,Ikbke,Adap2,Mcmbp,Rab10,Nck1,Hmga1,Vezt,Prnp,Ezr,Mcoln2,Lyn,Sec24b,Daxx,Gpd2,Sdc4,Rnaset2b,Nek6,Procr,Med21,Nfkbie,Lnpep,Ap3b1,Hk2,Ext1,Prdx5,Adar,Stat1,Tomm70a,Timeless,Gpc1,Hmox1,Gbp7,Stx6,Phf11d,Spen,Plagl1,Gem,Prpf38a,Slc25a25,Uaca,Tent4a,Lrp8,Tpm4,Tdrd7,Pstpip2,Rbpms,Tap1,Mier3,Mid1,Slc16a1,Abcc1,Katna1,Rars,Tapbp,Bcl6,Arl4a,Oas1a,Cacybp,Oas1g,Vcam1,Hat1,Smc5,Micall2,Psme1,Ifi213,Ehd1,Tor3a,Socs1,Gsap,Serp1,Dusp2,Sod2,Dock10,Whamm,Dbnl,Carmil1,Irgm2,Anp32a,Isg20,Rabgef1,Zhx2,Morc3,Bcl2l11,Dusp16 |
| 3.381e-05 | -10.29 | positive regulation of epithelial cell migration | biological process | GO:0010634 | 143 | 24 | 20694 | 1406 |
Akt3,Zc3h12a,Sirt1,Mmp9,Hmox1,Prkce,Serpine1,Cd40,Adora2b,Met,Src,Angpt1,Map4k4,Plk2,Thbs1,Ptgs2,Jun,Stat5a,Glipr2,Kdr,Hif1a,Plpp3,Vegfc,Pdgfb |
| 3.385e-05 | -10.29 | GO_ENDOSOME | MSigDB lists | GO_ENDOSOME | 719 | 88 | 15632 | 1249 |
Inpp5b,Antxr1,Snx10,Slc31a2,Myo1b,H2-Ab1,Scyl2,Fpr1,Rffl,Dbnl,Rab9,Ehd1,Src,Ifnar1,Plekhf2,Acpp,Cd164,Clcn5,Slc30a4,H2-Q7,Pml,Calcrl,Rabgef1,Lnpep,P2ry2,Kdr,Nox1,Adrb2,H2-Q4,Ezr,Rab32,Flt1,Fcgr1,Chmp4b,Arrdc4,Rab10,Wdfy1,H2-Aa,Snx2,Rapgef2,H2-Eb1,Gja1,Fzd5,Irf7,Map2k1,Vcam1,Irak2,Ikbke,Slc29a3,Mitd1,Crkl,Tlr3,Slc31a1,Rab21,Micall2,Slc39a4,Rab11fip1,Tnf,H2-Q6,Sgk3,Myd88,Sla,Cd14,Lipg,Cd74,Tab2,Atp11a,Ociad1,Mmd,Stx6,Cav1,Znrf1,Jak2,Ldlr,Rap2c,Pmepa1,Tlr9,Dgkh,Lpar1,Mmp14,Optn,Sqstm1,Il15,Gpc1,Slc48a1,Atp11b,Zc3hav1,Pikfyve |
| 3.395e-05 | -10.29 | GSE22611_UNSTIM_VS_6H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_DN | MSigDB lists | GSE22611_UNSTIM_VS_6H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_DN | 171 | 30 | 15632 | 1249 |
Ccr1,Ppp1r15a,Ccrl2,Dgka,Maff,Ebi3,Il13ra1,Ripk2,Socs3,Ak4,Slc43a3,Plcl2,Osbpl3,Slc29a3,Pf4,Src,Casp1,Ifnar1,Phldb1,Slc7a11,Sqstm1,Itpr1,Trip10,Cd40,Edn1,Mmp14,Evl,Sphk1,Slamf7,Clcn5 |
| 3.434e-05 | -10.28 | GO_POSITIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 18 | 8 | 15632 | 1249 |
Tlr9,Tlr3,Cav1,Tlr2,Nr1h3,Wdfy1,Peli1,Rsad2 |
| 3.434e-05 | -10.28 | BIOCARTA_CYTOKINE_PATHWAY | MSigDB lists | BIOCARTA_CYTOKINE_PATHWAY | 18 | 8 | 15632 | 1249 |
Il10,Il1a,Il18,Il12b,Tnf,Ifnb1,Il15,Il6 |
| 3.463e-05 | -10.27 | STAT_TF_prot_interaction | interpro domains | IPR013799 | 7 | 5 | 19984 | 1430 |
Stat5a,Stat1,Stat2,Stat4,Stat3 |
| 3.463e-05 | -10.27 | STAT_TF_DNA-bd_N | interpro domains | IPR012345 | 7 | 5 | 19984 | 1430 |
Stat3,Stat5a,Stat1,Stat2,Stat4 |
| 3.463e-05 | -10.27 | STAT_TF_DNA-bd | interpro domains | IPR013801 | 7 | 5 | 19984 | 1430 |
Stat3,Stat5a,Stat2,Stat1,Stat4 |
| 3.463e-05 | -10.27 | STAT_TF_coiled-coil | interpro domains | IPR015988 | 7 | 5 | 19984 | 1430 |
Stat3,Stat5a,Stat4,Stat1,Stat2 |
| 3.463e-05 | -10.27 | STAT_N_sf | interpro domains | IPR036535 | 7 | 5 | 19984 | 1430 |
Stat3,Stat5a,Stat4,Stat1,Stat2 |
| 3.463e-05 | -10.27 | STAT_TF_alpha | interpro domains | IPR013800 | 7 | 5 | 19984 | 1430 |
Stat3,Stat5a,Stat4,Stat2,Stat1 |
| 3.463e-05 | -10.27 | STAT | interpro domains | IPR001217 | 7 | 5 | 19984 | 1430 |
Stat5a,Stat4,Stat2,Stat1,Stat3 |
| 3.491e-05 | -10.26 | GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN | MSigDB lists | GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN | 163 | 29 | 15632 | 1249 |
Stx6,Adora2a,Cysltr2,Lmo4,Pdgfrb,Epsti1,Prkx,Tnfsf10,Tmem229b,Lyn,Cdyl2,Cers6,Cyfip1,Otud1,Mgat1,Ifnar1,Casp1,Pdgfc,Herc3,Sdc4,Sla,Kmo,Ddx58,Papss2,Ppm1l,Nr1h3,Rnf135,P2ry14,Arrdc4 |
| 3.511e-05 | -10.26 | GSE7852_LN_VS_THYMUS_TREG_DN | MSigDB lists | GSE7852_LN_VS_THYMUS_TREG_DN | 188 | 32 | 15632 | 1249 |
Zscan29,AA467197,Lmo4,Eno2,Rnf14,Hsd17b7,Prkar2b,Nfxl1,Slc43a3,Arid5b,Pcgf5,Smc5,Ldha,Lztfl1,Ift57,Cers6,Fut8,Ctsc,Irgq,Tnfsf8,Gpsm2,Eno1,Ezr,Plekha5,Rras2,Gnb4,Pde3b,Nmral1,Fam133b,Mxd1,Tpi1,Lif |
| 3.511e-05 | -10.26 | GSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP | MSigDB lists | GSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP | 188 | 32 | 15632 | 1249 |
Stat4,Oas1a,Egln3,Irf8,Lcp2,Slfn4,Pde4b,Fmnl2,Tfec,Frmd6,Slfn3,Ccl4,Tgfbi,Rcsd1,Map3k8,Filip1l,Oas1g,Cers6,C1ra,Phgdh,Tbc1d1,Parp14,Ifi44,Rnf24,Swap70,Tiparp,Extl2,Herc3,Spata13,Ubash3b,Calcrl,Mthfr |
| 3.511e-05 | -10.26 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP | 188 | 32 | 15632 | 1249 |
Ttc39c,Cyfip1,Cnn2,Rab32,Ogfrl1,Ccnd1,Rai14,Rhoq,Fcgr2b,Pla2g4a,Il4ra,Cd180,Nek6,Hhex,Hck,Cd34,Tnfsf14,Gna15,Ccl5,Dusp6,Myadm,Plek,Kctd12,Procr,Acsl1,Ier3,Clec4d,Acvr1b,Ebi3,Abcc1,Gcnt2,Rgs1 |
| 3.526e-05 | -10.25 | PID_INTEGRIN2_PATHWAY | MSigDB lists | PID_INTEGRIN2_PATHWAY | 28 | 10 | 15632 | 1249 |
Tgfbi,F11r,Icam1,Itgal,C3,Plaur,Plau,F10,Vcam1,Plat |
| 3.526e-05 | -10.25 | TSAI_RESPONSE_TO_RADIATION_THERAPY | MSigDB lists | TSAI_RESPONSE_TO_RADIATION_THERAPY | 28 | 10 | 15632 | 1249 |
Cd69,Vegfc,Il6,Thbs1,Plat,Isg15,Serpine1,Oas3,Egr1,Ifit2 |
| 3.526e-05 | -10.25 | GO_NECROTIC_CELL_DEATH | MSigDB lists | GO_NECROTIC_CELL_DEATH | 28 | 10 | 15632 | 1249 |
Mlkl,Ripk3,Tmem123,Cd14,Birc2,Traf2,Casp1,Fas,Tlr3,Tnf |
| 3.526e-05 | -10.25 | GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 28 | 10 | 15632 | 1249 |
Irak3,Myd88,Tlr1,Tnip1,Irak2,Cd14,Tab2,Tlr2,Tlr9,Tlr6 |
| 3.526e-05 | -10.25 | GNF2_SPI1 | MSigDB lists | GNF2_SPI1 | 28 | 10 | 15632 | 1249 |
Pilra,Tnfsf10,Igsf6,Tlr1,Gca,Vasp,Hck,P2ry13,Csf3r,Fpr1 |
| 3.526e-05 | -10.25 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_UP | 28 | 10 | 15632 | 1249 |
Hmox1,Tulp3,Chic2,Sgms2,D1Ertd622e,Gclm,Gclc,Kitl,Ldlr,Phlpp2 |
| 3.548e-05 | -10.25 | transforming growth factor beta receptor signaling pathway | biological process | GO:0007179 | 83 | 17 | 20694 | 1406 |
Jun,Fos,Fut8,Cited2,Bambi,Acvr1b,Zyx,Pml,Ptk2,Bmp2,Acvr1,Dcp1a,Acvrl1,Gcnt2,Ccl2,Src,Sirt1 |
| 3.548e-05 | -10.25 | HOFMANN_CELL_LYMPHOMA_UP | MSigDB lists | HOFMANN_CELL_LYMPHOMA_UP | 58 | 15 | 15632 | 1249 |
Ifna6,Rab9,Myc,Ccnd1,Mdm2,Ifna5,Gpr68,Ccng2,Rel,Irf8,Ifna1,Ifna2,Nck1,Il13ra1,Il18 |
| 3.552e-05 | -10.25 | peptide antigen binding | molecular function | GO:0042605 | 38 | 11 | 20217 | 1400 |
H2-Q6,Tap2,H2-Q4,Tap1,H2-Q7,H2-Ab1,H2-T24,H2-M2,H2-Aa,H2-T22,H2-T10 |
| 3.563e-05 | -10.24 | GO_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | 155 | 28 | 15632 | 1249 |
Dennd1b,Psma6,Nfkbia,Syk,Psmb9,Psmd10,Cd38,Nck1,Psme1,Malt1,Tab2,Psmb10,H2-Aa,Psme2,H2-Eb1,Pde4b,Psmb8,Ikbkg,Nfkb1,Rnf31,Lcp2,Ptprj,H2-Ab1,Psmb6,Ripk2,Cacnb3,Lyn,Pik3cd |
| 3.563e-05 | -10.24 | GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_UP | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_UP | 155 | 28 | 15632 | 1249 |
Crlf3,Nod1,Traf5,Pde3b,Usp18,Tnfsf8,Ly75,Mafk,Spsb1,Ifit2,Gypc,Bcl2l11,Itpr1,Dse,Gpr18,Arid5a,Znrf1,Ap3m2,Sp110,Atp10a,St3gal1,Pim2,Cd200,Dck,Pik3cd,Ext1,Dgka,Ccnj |
| 3.563e-05 | -10.24 | MODULE_197 | MSigDB lists | MODULE_197 | 155 | 28 | 15632 | 1249 |
Zfp324,Nfkb1,Ccne1,Junb,Gfi1,Lhx2,Cxcl1,Dek,Mcm6,Mafg,Ptger4,Ccng2,Mid1,Egr2,Myc,Rbbp8,Jun,Cited2,Ets2,Fos,Eif2ak2,Etv5,Hif1a,Pttg1,Kdm4a,Tulp3,Egr1,Atf3 |
| 3.563e-05 | -10.24 | GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 155 | 28 | 15632 | 1249 |
S100a8,Cav1,Casp8,Osm,Inhba,Sirt1,Casp2,Nox1,Mmp9,Jak2,Ppp2r1b,Tnfsf10,Thbs1,Plaur,Fam162a,Bcl2l11,Traf2,Ptpn2,Ctsc,Bnip3,Ifnb1,Nck1,Fas,Atf3,Pml,Apaf1,Ripk3,Plagl2 |
| 3.572e-05 | -10.24 | CASPASE_CYS | prosite domains | PS01122 | 10 | 6 | 13278 | 1037 |
Casp1,Casp4,Casp2,Casp7,Casp8,Casp3 |
| 3.572e-05 | -10.24 | CASPASE_P10 | prosite domains | PS50207 | 10 | 6 | 13278 | 1037 |
Casp7,Casp2,Casp4,Casp1,Casp3,Casp8 |
| 3.573e-05 | -10.24 | regulation of protein ubiquitination | biological process | GO:0031396 | 200 | 30 | 20694 | 1406 |
Dtx3l,Svbp,Isg15,Gclc,Trib3,Birc2,Dnaja1,Sphk1,Psmd10,Prkce,Dnajb2,Nod2,Cav1,Trib1,Tnfaip3,Fbxo4,Angpt1,Peli1,Arrdc4,Adrb2,N4bp1,Parp10,Nmi,Caml,Birc3,Dcun1d3,Daxx,Gbp4,Ripk2,Tspo |
| 3.577e-05 | -10.24 | GSE10147_IL3_VS_IL3_AND_CPG_STIM_PDC_UP | MSigDB lists | GSE10147_IL3_VS_IL3_AND_CPG_STIM_PDC_UP | 131 | 25 | 15632 | 1249 |
Ahr,Tulp3,P2ry14,Isg15,Ch25h,Prdm1,Lrp8,Lif,Dhx58,Dusp8,Gbp4,Gbp9,Psmb9,Nlrc5,N4bp1,Rapgef5,Dio2,Cmklr1,Adam19,Kif5c,Dgka,Tdrd7,Pdgfrb,Fosb,Gja1 |
| 3.578e-05 | -10.24 | STAT_int | pfam domains | PF02865 | 7 | 5 | 18711 | 1348 |
Stat5a,Stat4,Stat3,Stat1,Stat2 |
| 3.578e-05 | -10.24 | STAT_bind | pfam domains | PF02864 | 7 | 5 | 18711 | 1348 |
Stat2,Stat1,Stat3,Stat4,Stat5a |
| 3.578e-05 | -10.24 | STAT_alpha | pfam domains | PF01017 | 7 | 5 | 18711 | 1348 |
Stat2,Stat1,Stat4,Stat3,Stat5a |
| 3.612e-05 | -10.23 | GSE4590_SMALL_VS_LARGE_PRE_BCELL_DN | MSigDB lists | GSE4590_SMALL_VS_LARGE_PRE_BCELL_DN | 139 | 26 | 15632 | 1249 |
Rgl1,Pde4b,Cd69,Tdrd7,Spint2,Rap1gap2,Akt3,Cnn3,Slc2a6,Aida,Adrb2,Ebi3,Tagap,Cmpk2,Lrrc8c,Spn,Nfkbia,Arhgap26,Glipr2,Rbpms,Ggct,Klf8,Sell,Prrg4,Nod1,Cd80 |
| 3.612e-05 | -10.23 | GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_UP | MSigDB lists | GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_UP | 139 | 26 | 15632 | 1249 |
Cep350,Ankib1,Mfap3l,Plekha5,Plekhf2,Stx11,Tmem176a,Dtnb,Adora2a,Fut8,Nr3c1,Ksr1,Phlda1,Phlpp2,Mmp14,Kcna3,Mmp25,Fgr,Itga4,Abr,Egr1,Traf3ip2,Apba1,Dusp14,Cdkn1a,Rnd3 |
| 3.636e-05 | -10.22 | GO_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION | 93 | 20 | 15632 | 1249 |
Jun,Cav1,Gja1,Ccl12,Stat5a,Nr4a1,Acvrl1,Sirt1,Rictor,Ccr3,Pdgfb,Nrp2,Hif1a,Stat1,Egr3,Angpt1,Htr2b,Kdr,Bmp2,Thbs1 |
| 3.651e-05 | -10.22 | G_GB1_RHD3_dom | interpro domains | IPR030386 | 15 | 7 | 19984 | 1430 |
Gbp8,Gbp4,Gbp2b,Gbp7,Gbp3,Gbp2,Gbp9 |
| 3.651e-05 | -10.22 | Guanylate-bd_N | interpro domains | IPR015894 | 15 | 7 | 19984 | 1430 |
Gbp2,Gbp9,Gbp4,Gbp2b,Gbp7,Gbp3,Gbp8 |
| 3.664e-05 | -10.21 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_6H_UP | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_6H_UP | 180 | 31 | 15632 | 1249 |
Ust,Slfn9,Clcn7,Osbpl3,Acp2,Ptger4,Rcsd1,Grina,Wdr59,Cd69,Syne2,Casp8,Irf7,Mapkbp1,Slc28a2,Hvcn1,Rnf139,Isg15,Ifih1,Nmral1,Ddx58,Dusp2,Slfn8,Cd200r4,Cdyl2,Fgl2,Ifnar1,Zswim4,Ifit2,Nlrc5,Gramd1a |
| 3.664e-05 | -10.21 | GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_UP | 180 | 31 | 15632 | 1249 |
Cdk5r1,Irs2,Ifih1,Ahr,Slc16a1,Tmem184b,Homer1,Spryd7,Srm,Plekhf2,Ifit2,Hsph1,Dusp4,Chst11,Lztfl1,Slc15a3,Egr2,Slc25a22,Mafg,Serpinb9,Rcn1,Osgin2,Odc1,Dnaja2,Rcl1,Vegfc,Cflar,Zc3h12c,Cacybp,Plek,Maff |
| 3.722e-05 | -10.20 | TAP binding | molecular function | GO:0046977 | 11 | 6 | 20217 | 1400 |
H2-Q4,Tap1,H2-Q7,Tapbp,H2-Q6,Tap2 |
| 3.762e-05 | -10.19 | CHUANG_OXIDATIVE_STRESS_RESPONSE_UP | MSigDB lists | CHUANG_OXIDATIVE_STRESS_RESPONSE_UP | 23 | 9 | 15632 | 1249 |
Edn1,Nqo1,Gdf15,Lif,Egr1,Hmox1,Fas,Jun,Hspa1a |
| 3.762e-05 | -10.19 | BIOCARTA_GLEEVEC_PATHWAY | MSigDB lists | BIOCARTA_GLEEVEC_PATHWAY | 23 | 9 | 15632 | 1249 |
Myc,Jak2,Stat1,Crkl,Stat5a,Map2k4,Jun,Map2k1,Fos |
| 3.804e-05 | -10.18 | GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_DN | MSigDB lists | GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_DN | 172 | 30 | 15632 | 1249 |
Sla,Bmp2,Palld,P2ry14,Socs1,Sell,Upp1,Lrch1,Rhoq,Rsad2,Vcan,Bcl2l11,Cst7,Flt1,Bcl6,Jun,Il1rn,Acp2,Nfil3,Ptgir,Kcna3,Med13,Spint2,Kctd12,Rasgrp1,Ccrl2,Rgl1,Lcp2,Sema3c,Myo1b |
| 3.811e-05 | -10.17 | MODULE_209 | MSigDB lists | MODULE_209 | 86 | 19 | 15632 | 1249 |
Mmp14,Ctsc,C1ra,Pla2g7,Mmp13,Casp1,Lap3,Casp4,Serpine1,Timp1,Psmb9,Serpinb2,Plat,F10,Plau,Olr1,Mmp9,Hmgcs1,Hp |
| 3.811e-05 | -10.17 | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | MSigDB lists | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | 86 | 19 | 15632 | 1249 |
Rictor,Mdm2,Phlpp1,Pdgfb,Stat3,Akt3,Prkce,Pde1b,Pdgfrb,Map2k1,Nr4a1,Src,Stat5a,Cdkn1a,Prkar2b,Trib3,Crkl,Nck1,Stat1 |
| 3.812e-05 | -10.17 | GBP | pfam domains | PF02263 | 15 | 7 | 18711 | 1348 |
Gbp7,Gbp9,Gbp2b,Gbp2,Gbp4,Gbp3,Gbp8 |
| 3.812e-05 | -10.17 | GO_REGULATION_OF_CELL_KILLING | MSigDB lists | GO_REGULATION_OF_CELL_KILLING | 65 | 16 | 15632 | 1249 |
H2-Q7,Il12b,Serpinb9,Icam1,Tap1,Ripk3,Ccl12,Bcl2l11,H2-Q4,Pik3r6,Nos2,Il10,H2-Q6,Stap1,Rasgrp1,Il12rb1 |
| 3.830e-05 | -10.17 | SH2 | prosite domains | PS50001 | 103 | 21 | 13278 | 1037 |
Sla,Lcp2,Socs7,Socs1,Fgr,Cish,Syk,Stat5a,Nck1,Stap1,Lyn,Stat3,Stat4,Rin2,Socs3,Hck,Stat2,Src,Crkl,Jak2,Stat1 |
| 3.840e-05 | -10.17 | GO_EMBRYO_DEVELOPMENT | MSigDB lists | GO_EMBRYO_DEVELOPMENT | 855 | 101 | 15632 | 1249 |
Maff,Inpp5b,Pdgfb,Klf2,Mthfd1l,Junb,Tshz1,Vegfc,Sec24b,Kdm6b,Dusp5,Acvr1,Acvrl1,Fut8,Setdb2,Eno1,Rbbp8,Dusp1,Lrp4,Notch1,Bmp2,Hif1a,Intu,Itga4,Hlx,Hhex,Lif,Apba1,Il10,P2ry2,Ptch1,Clic5,Kdr,Acvr1b,Rcn1,Mafg,Socs3,Chst11,Spry2,Edn1,Flt1,Bcl2l11,Sbds,Flrt3,Angpt1,Hinfp,Adar,Abr,Inhba,Mmp13,Fzd1,Ppp2r3a,Vasp,Ext1,Fzd5,Hopx,Map2k1,Med21,Gja1,Htr2b,Keap1,Kitl,Nr4a3,Hdac1,Phgdh,Mgat1,Tnf,Txnrd1,Plod3,Apaf1,Pdgfc,Pbx1,Tulp3,Zfp281,Prdm1,Rictor,Zeb1,Sema3c,Lmo4,Casp8,Atm,Lhx2,Rpgrip1l,Sema4c,Ptk2,Itga5,Mmp9,Phactr4,Ift57,Dusp4,Mmp14,Dusp2,Spic,Cited2,Ets2,Itgav,Col4a2,Sdc4,Slc30a1,Cdk5r1,Fas |
| 3.849e-05 | -10.17 | peptide secretion | biological process | GO:0002790 | 172 | 27 | 20694 | 1406 |
Rnf19b,Isg15,Notch1,Nlrp3,Traf3ip2,Il1rn,Pou2f2,Svbp,Optn,Nod2,Lyn,Notch2,Tlr2,Rab10,Nlrc4,Itgav,Tlr6,Edn1,Lcp2,Stxbp3,Dio2,Plek,Trem1,Aim2,Nos2,Mcoln2,Il6 |
| 3.909e-05 | -10.15 | GSE14350_IL2RB_KO_VS_WT_TREG_DN | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TREG_DN | 189 | 32 | 15632 | 1249 |
Ptprj,Dgkh,Smox,Osbpl3,Plek,Zc3h12c,Reps1,Pstpip2,St3gal5,Tifa,Cxcl2,Fam72a,Prdm1,Upp1,Tab2,Tmtc2,Ppm1l,Traf1,Sdc4,Cd83,Cd38,Axl,Apobec3,Slc16a3,Ttc39c,Swap70,Tcf4,Sat1,Slc15a3,Rhoq,Slc39a4,Chst11 |
| 3.909e-05 | -10.15 | GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_UP | MSigDB lists | GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_UP | 189 | 32 | 15632 | 1249 |
Ccl12,Srm,Bcl2l11,Bcl2a1b,Dusp1,Parp8,Nr4a1,Stat5a,Cnn2,Bcl2a1d,Dusp2,Irf4,Mapkapk2,Ier2,Relb,Batf,Slc25a25,Lap3,Mov10,Gja1,Tnfrsf1b,Hk1,Jarid2,Hk2,Ext1,St7,Gpd2,Odc1,Fam162a,Cd82,Nfkb2,Bcl2a1a |
| 3.909e-05 | -10.15 | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_UP | 189 | 32 | 15632 | 1249 |
Rnf135,Dmxl2,Il4ra,Cyth3,Mapkapk2,Apba1,Fas,Tmem176b,Olfml3,Bmp2,Birc2,Arid5a,Klf6,Parp8,Rab32,Ctsc,Rab20,Rnf145,Filip1l,Parp3,Dyrk2,Mtmr14,Abcc1,Mob3c,Osbpl3,Vps54,Casp8,Cd86,Samsn1,Klf2,Trim21,Spen |
| 3.909e-05 | -10.15 | GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_DN | MSigDB lists | GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_DN | 189 | 32 | 15632 | 1249 |
Klf2,Myo1b,Ifit3,Plk2,Slc4a7,Ext1,Ampd3,Tgfbi,Ifit3b,Ier3,Etnk1,Ptprj,Socs3,Thbs1,Jun,Ets2,Tiparp,Klf3,Hivep2,Txnrd1,N4bp1,Kdm5b,Acvr1,Cp,Carhsp1,Rhoq,Egr2,Irs2,Slco3a1,Isg15,Gbp2,Sdc4 |
| 3.911e-05 | -10.15 | GO_PROTEIN_POLYUBIQUITINATION | MSigDB lists | GO_PROTEIN_POLYUBIQUITINATION | 232 | 37 | 15632 | 1249 |
Rnf14,Rnf31,Lnpep,Ankib1,Psmb8,Psme2,Trim21,Ube2e2,Trim56,Rnf19a,Psmb6,Herc6,Rnf19b,Rnf145,Znrf1,Rnf114,Trim36,Spsb1,Birc2,Traf2,Psmd10,Psmb9,Peli1,Rffl,Rnf24,Psma6,Rnf139,Ube2e1,Psme1,Psmb10,Dtx3l,Trim12c,Fbxo4,Ube2f,Rnf34,Bfar,Tnfaip3 |
| 3.917e-05 | -10.15 | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | 79 | 18 | 15632 | 1249 |
Tnfsf4,Hlx,Tlr3,Tmem176b,Ubash3b,Irf1,Cd74,Trib1,Il4ra,Lyn,Myc,Inhba,Nfkbid,Gpr68,Tmem176a,Ifnb1,Bcl6,Ptpn2 |
| 3.927e-05 | -10.15 | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE | 72 | 17 | 15632 | 1249 |
Cycs,Irf4,Casp3,Myc,Pnp2,Rin2,Hk2,Hivep2,Cav1,Cflar,Ldlr,Slamf7,Pgk1,St3gal1,Ldha,Ell2,Slc31a1 |
| 3.927e-05 | -10.15 | MORI_SMALL_PRE_BII_LYMPHOCYTE_DN | MSigDB lists | MORI_SMALL_PRE_BII_LYMPHOCYTE_DN | 72 | 17 | 15632 | 1249 |
Ier2,Abr,St3gal6,Cox18,Ccnd2,Rbl1,Cdkn1a,Tuba4a,Casp1,Hsph1,Ehd1,Psmb8,Gbp7,Eno1,Zyx,Ctsc,Stat4 |
| 3.955e-05 | -10.14 | LAU_APOPTOSIS_CDKN2A_UP | MSigDB lists | LAU_APOPTOSIS_CDKN2A_UP | 52 | 14 | 15632 | 1249 |
Fas,Apaf1,Cdkn1a,Tnfaip3,Traf5,Cflar,Casp8,Nfkbia,Bcl2l11,Casp1,Casp2,Bnip3,Cycs,Myc |
| 3.991e-05 | -10.13 | SUNG_METASTASIS_STROMA_UP | MSigDB lists | SUNG_METASTASIS_STROMA_UP | 101 | 21 | 15632 | 1249 |
Hmgcs1,Cd55,Uaca,Ptgs2,Map3k8,Sdc4,Slc16a1,Etv5,Dcbld2,Spsb1,Junb,Agrn,Ass1,P4ha1,Dusp6,Plk2,Lmo4,Plod2,Cnn3,Tnc,Vcan |
| 4.010e-05 | -10.12 | GSE40274_CTRL_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 124 | 24 | 15632 | 1249 |
Phgdh,Tnfsf8,Spn,Hsph1,Cst7,Hk3,Crim1,Pilra,Bmp2,Sdc1,Traf1,Fas,Adora2a,Hap1,Pdgfb,Slpi,Plekhg1,Ccl5,P4ha1,Epsti1,Trafd1,Snn,Mefv,Hp |
| 4.010e-05 | -10.12 | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN | MSigDB lists | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN | 124 | 24 | 15632 | 1249 |
Ttc39c,Zswim4,Gsdmd,Slc25a37,Nfkbia,Gadd45b,Gadd45g,Acvr1,Errfi1,Abcb1a,Col18a1,Relb,Dusp6,Jag1,Rapgef2,Alas1,Ube2l6,Arid5b,Trib3,Acvr1b,Hmgcs1,Ppfibp2,Ldlr,Gcnt2 |
| 4.023e-05 | -10.12 | protein homodimerization activity | molecular function | GO:0042803 | 936 | 97 | 20217 | 1400 |
Timeless,Atf3,Nos2,Ggct,Hmgcs1,Foxp4,Ccl5,Rasgrp1,Klrk1,Nr3c1,Nampt,Tpst1,Nlrc4,Bcl2a1b,Trim12c,Cacybp,Pdgfc,Fbxo4,Jun,Cst7,Txnrd1,Irak2,Fzd1,Hp,Pdgfb,Bnip3,Gdf15,Irak3,Acvr1,Mthfd1l,Nod1,Prdx1,Gbp2,Tap1,Acpp,Nr4a3,Srm,Daxx,Sqstm1,Glipr2,Ripk2,Rbpms,Gbp3,Ikbkg,Cebpd,Asns,Gbp2b,Dck,Hk1,Il12b,Tpi1,Snx2,Tap2,Nfkb1,Keap1,Dgkh,Ahr,Bcl2a1d,Lcn2,Odc1,Eno2,Cd69,Lrp4,Hdc,Plek,Eno1,Hmox1,Stat1,Slc39a13,Stat3,Jmjd6,Mid1,Pml,Hhex,Tcf4,Ptgs2,Pvr,Bcl2a1a,Flrt3,Wars,Gch1,Gca,Slc16a1,Nectin4,Ext1,Zhx2,Bmp2,Csf1,Max,Tpm4,Adrb2,Mitd1,Nr4a1,Gsr,Chmp4b,Dst,Nectin2 |
| 4.035e-05 | -10.12 | negative regulation of cellular response to oxidative stress | biological process | GO:1900408 | 53 | 13 | 20694 | 1406 |
Hk3,Sirt1,Met,Hsph1,Txn1,Glrx,Il10,Hif1a,Nr4a3,Sod2,Fzd1,Ncoa7,Slc7a11 |
| 4.042e-05 | -10.12 | establishment of localization | biological process | GO:0051234 | 3485 | 292 | 20694 | 1406 |
Atp11b,Ap3m2,Il6,G3bp2,Hif1a,Rrbp1,Gem,Thbs1,Grk3,Cacnb3,Trem1,Plek,Slc15a3,Ccnd1,Nr4a3,Clcn5,Slc30a4,Hk2,Itgav,Gja1,Rtp4,Ikbkg,Mppe1,Pmaip1,Mapkapk2,Isg15,Slc39a14,Slc7a2,Mdm2,Lrrc8c,P2ry12,Cacna1d,Rffl,Magohb,Atp6v1d,Slc16a3,Egr2,Cdkn1a,Mfsd7a,Pikfyve,Pla2g4a,Cp,Abcc1,Fcgr2b,Fnbp1l,Ift57,Rtn2,Stra6l,Myd88,Serp1,Met,Slc37a3,Calcrl,Notch2,Slc7a5,Rab10,Chic2,Clic4,Stxbp3,Ccdc88b,Il1rn,Traf3ip2,Slc28a2,Bnip3,Ednrb,Slc4a7,Cd14,Kcna3,Arl4a,Piezo1,Dst,Slc25a25,Ero1l,Ptafr,Lcn2,Kcnj2,Fpr2,Snx10,Sec24a,Map2k1,Ly75,4932438A13Rik,Nxf1,Treml4,Tmc3,Aftph,Hck,Stat3,Bcl2l11,Src,Inhba,Tnfaip3,Adar,Rin2,Slco3a1,Rab19,Lrp11,Tlr6,Lcp2,Nlrc4,Gramd1a,Rgs14,Ranbp2,Nlrp3,Optn,Orai2,Pou2f2,Abcc4,Apba1,Stat5a,Pdpn,Rhou,Ap3b1,Pnpt1,Mecp2,Kif5c,Dio2,D1Ertd622e,Calhm6,Ezr,Scyl2,Slc9a1,Fcgr1,Stard5,Arrdc4,Slc30a1,Adrb2,Nfkbia,Ppfia3,Spry2,Slc48a1,Dennd1b,Antxr1,Hspa2,Stx6,Rhoq,Rab3ip,Rnf19b,Ptk2,Slc25a22,Rac3,Nr1h3,Vps54,Myc,Htr2a,Reps1,Syne2,Cox18,Anp32a,Stard7,Atm,Kpna3,Acsl1,Stoml1,Slc25a37,Slc39a13,Whamm,Slc43a3,Plscr1,Rab9,Atp11a,Lyn,Cav1,Slc7a11,Abcc5,Parp11,Slc31a2,Spire1,Slc7a8,Dbnl,Tbc1d13,Rab32,Slc39a4,Itpr1,Samd9l,Htr2b,Rims3,F11r,Pdzd11,Axl,Acsl5,Irf8,Gpsm2,Tap1,Cd274,Hhex,Arf4,Ier3,Slc2a1,Fcho2,Snx2,Sh3bp4,Ric1,Osbpl3,Syk,Stxbp1,Pml,Ccr1,Slc44a1,Rasgrp1,Milr1,Slc13a3,Arl5c,Rab20,Ikzf1,Uchl1,Slc16a1,Jmjd6,Ccl5,Rabgef1,Hk1,Nlgn2,Atp13a1,Phip,Igf2bp2,Msr1,Dennd2a,Dync1h1,Arl5b,Fabp3,Cd74,Tnfaip2,Lipg,Sec24b,Tbc1d1,Slc25a12,Ift22,Actb,Malt1,Lrp4,Cyth3,Mul1,Rhbdf2,Nos2,Scn1b,Slc29a3,Atp10a,Rilpl1,Micall2,Hap1,Casp1,Xcr1,Ldlr,Rrs1,Stx11,Nfkbie,Myo1b,Fam53c,Tlr2,Marcksl1,Slc31a1,Marco,Trip10,Plekhf2,Cd302,Scarf1,Chmp4b,Notch1,Tomm70a,Itgal,Tspo,Fchsd2,Rab11fip1,Ehd1,Aim2,Mcoln2,Abcb1a,Atp2b4,Cenpe,Hspa1a,Kif3c,Rab21,Cnp,Hinfp,Xkr8,Clcn7,Carmil1,Hvcn1,Nod2,Lrp8,Rubcnl,Tap2,Stau1,Dnaja1,Edn1,Clic5,Nectin2,Svbp,Slc12a9,Itga4,Dtx3l,Zfp36 |
| 4.069e-05 | -10.11 | regulation of growth of symbiont in host | biological process | GO:0044126 | 21 | 8 | 20694 | 1406 |
Myd88,Sqstm1,Tnf,Il12b,Tlr2,Nod2,Il10,Irf8 |
| 4.069e-05 | -10.11 | T-helper 1 type immune response | biological process | GO:0042088 | 21 | 8 | 20694 | 1406 |
Il18bp,Relb,Sema4a,Il12b,Il18rap,Gadd45g,Spn,Il18 |
| 4.071e-05 | -10.11 | negative regulation of leukocyte apoptotic process | biological process | GO:2000107 | 68 | 15 | 20694 | 1406 |
Axl,Cd74,Tnfsf4,Fcgr2b,Hcls1,Il18,Bcl2a1a,Irs2,Nod2,Stat5a,Kitl,Ccl5,Serpinb9,Arg2,Hif1a |
| 4.077e-05 | -10.11 | REACTOME_IL_6_SIGNALING | MSigDB lists | REACTOME_IL_6_SIGNALING | 10 | 6 | 15632 | 1249 |
Tyk2,Jak2,Stat3,Il6,Stat1,Socs3 |
| 4.083e-05 | -10.11 | GO_ACTIVATION_OF_MAPK_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_MAPK_ACTIVITY | 132 | 25 | 15632 | 1249 |
Mul1,Cd74,Tab2,Mapkapk2,Mdfic,Daxx,Bmp2,Nod1,Syk,Tnf,Map3k6,Nod2,S1pr2,Dbnl,Fpr1,Adora2b,Lpar1,Dusp5,Ripk2,Il1b,Irak2,Thbs1,Map2k1,Ikbkg,Dusp6 |
| 4.090e-05 | -10.10 | GSE19512_NAUTRAL_VS_INDUCED_TREG_DN | MSigDB lists | GSE19512_NAUTRAL_VS_INDUCED_TREG_DN | 181 | 31 | 15632 | 1249 |
Flt1,Casp1,Tcf4,Nr3c1,Pla2g4a,Pnp2,Myc,Vcan,Cebpd,Gpr68,Rnd3,Ciita,Sla,Olr1,Rgl1,Tuba4a,Tnfrsf1b,Rel,Sipa1l1,Kctd12,Met,Endod1,Ifi35,Tlr3,Il2rg,Serpinb9,Cxcl1,Ralgds,Ccl4,Prkx,Igf1r |
| 4.090e-05 | -10.10 | GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 181 | 31 | 15632 | 1249 |
Notch1,Batf,Traf5,Usp18,Arrdc4,Fgl2,Ift57,Slc15a3,Homer1,Gpr18,Spsb1,Ifit1bl1,Axl,Cst7,Ass1,Abcc4,Pmepa1,Cd82,Trib1,Mthfd2,Ptger4,Rnf19b,Ebi3,Ell2,AA467197,Psme2,Hopx,Cnp,Atm,Ifit1bl2,Ccl5 |
| 4.090e-05 | -10.10 | MTOR_UP.N4.V1_UP | MSigDB lists | MTOR_UP.N4.V1_UP | 181 | 31 | 15632 | 1249 |
Asns,Vps54,Rims3,Gch1,Slc39a14,Ddit4,Slc7a5,Trib3,Etnk1,Slc31a1,Traf3ip2,Lhx2,Nfil3,Gfpt1,Clic4,Ldlr,Itpr1,Ass1,Slc7a11,Ifrd1,Bnip3,Phgdh,Ccdc86,Slc39a4,Arl4a,Arg2,Gbe1,Fas,Atf3,Batf,Cutc |
| 4.090e-05 | -10.10 | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_DN | MSigDB lists | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_DN | 181 | 31 | 15632 | 1249 |
Ccl12,Srm,Parp8,Tnf,Arhgef3,Pnp2,Rhoq,Gclm,Tbc1d1,Hdac1,Agtrap,Sell,Sdc1,Cd74,Slc48a1,Sla,Batf,Slc25a25,Brwd3,Snx10,Ppp1r15a,Csf1,Trim21,Cnn3,Kctd12,Hat1,Pim1,Cd82,Serpinb2,Ldlr,Snn |
| 4.090e-05 | -10.10 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP | 181 | 31 | 15632 | 1249 |
Ms4a6d,Cacnb3,Phf6,Kif3c,Nr4a3,St3gal1,Ptgir,Pcgf5,Clic4,Ppm1k,Sipa1l1,Birc3,Abtb2,4930523C07Rik,Flnb,Tulp3,Zfp281,Il4ra,Ifit1,Rab3ip,Klf7,Myo10,Rbl1,Bcl6,Tiparp,Ezr,Stat5a,Spsb1,Kremen1,Tbc1d1,Peli1 |
| 4.090e-05 | -10.10 | GSE26559_TCF1_KO_VS_WT_LIN_NEG_CELL_UP | MSigDB lists | GSE26559_TCF1_KO_VS_WT_LIN_NEG_CELL_UP | 181 | 31 | 15632 | 1249 |
Jarid2,Zfp36,Piezo1,Ext1,Spint2,Stx6,Slc39a14,Egr3,Sec24a,Clic4,Bcl2a1a,Il1rn,Nfil3,Cst7,Bcl2a1b,Aoah,Tspan3,Ppp2r5a,Egr2,Ctsc,Ccng2,Bcl2a1d,Plk3,Marcksl1,Ube2e1,Socs1,Il4ra,Slc30a1,Il1a,Dcp2,Upp1 |
| 4.090e-05 | -10.10 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | 181 | 31 | 15632 | 1249 |
Peli1,Dusp2,Cited2,Tiparp,Fos,Timp1,Ifit1bl1,Klf6,Dusp1,Klf3,Tnfaip3,Klf7,Irs2,Nlrp3,Arl4a,Plk3,Rap1gap2,Cd69,Btg2,Fosb,Rnaset2a,Klf2,Ifit1bl2,Junb,Rnaset2b,Tmem123,Plcl2,Fndc3a,Dyrk2,Sema4c,Ptger4 |
| 4.090e-05 | -10.10 | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_UP | 181 | 31 | 15632 | 1249 |
Idi1,Trafd1,Glrx,Mtmr14,Casp7,Parp3,Aida,H2-Aa,Nmi,Tor3a,Ttc9c,Txn1,Tap2,Lgals9,Extl2,Prdx1,Chmp4b,Samhd1,Tap1,Prpf38a,Marcksl1,Pml,Cd74,Cyth3,Trim12c,Lztfl1,Tapbp,Ifit2,Apobec3,Psmb9,Mgat1 |
| 4.090e-05 | -10.10 | GSE14350_IL2RB_KO_VS_WT_TEFF_DN | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TEFF_DN | 181 | 31 | 15632 | 1249 |
Prdm1,Socs1,Gclc,Slc16a1,Rras2,Trp53i11,Gbp2,Apobec3,Ezr,Plac8,Hmga1,Mgat1,Slc39a4,Peli1,Dock10,Treml2,Vcan,4932438A13Rik,Ptgir,Map2k4,Adora2b,Gfi1,Cmpk2,Gng12,Myadm,Cdyl,Gbp7,Il10,Asns,Hivep3,Il12rb1 |
| 4.105e-05 | -10.10 | DARWICHE_PAPILLOMA_RISK_LOW_UP | MSigDB lists | DARWICHE_PAPILLOMA_RISK_LOW_UP | 140 | 26 | 15632 | 1249 |
Cx3cl1,Rhoh,Lif,Chst11,Gclm,Traf2,Spic,Mgat1,Eno1,Axl,Srm,Pfkl,Fam162a,Esd,Il1b,Pgk1,Cmpk2,Pmepa1,Ldha,Jag1,Scn1b,Slpi,Cacybp,Plekha4,S100a8,Txn1 |
| 4.105e-05 | -10.10 | MIKKELSEN_MCV6_LCP_WITH_H3K4ME3 | MSigDB lists | MIKKELSEN_MCV6_LCP_WITH_H3K4ME3 | 140 | 26 | 15632 | 1249 |
Mark2,Tnks1bp1,Zbp1,Tmem176b,Rsad2,Gpr35,Gsta3,Glrx,Slfn3,Ikbke,Tnfsf10,Serpinb9,Tapbpl,Ifi35,Csf3,Wars,Xaf1,Oas2,Tmem176a,Isg20,Trim21,Fabp7,Gbgt1,Slfn4,C1rl,Snx10 |
| 4.116e-05 | -10.10 | regulation of T cell migration | biological process | GO:2000404 | 46 | 12 | 20694 | 1406 |
Ccl5,Cd200,Tnfsf14,Ripk3,Tnfrsf14,Lrch1,Cxcl10,Crkl,Tnfsf4,Lgals9,Itga4,Spn |
| 4.116e-05 | -10.10 | positive regulation of phospholipid metabolic process | biological process | GO:1903727 | 46 | 12 | 20694 | 1406 |
Htr2a,Src,Pdgfrb,Fpr2,Fabp3,Pdgfb,Fgr,Htr2b,Flt1,Nod2,Pcx,Lyn |
| 4.116e-05 | -10.10 | positive regulation of nitric oxide biosynthetic process | biological process | GO:0045429 | 46 | 12 | 20694 | 1406 |
Il6,Klrk1,Klf2,Jak2,Tlr6,Sod2,Ptgs2,Tnf,Icam1,Tlr2,Il1b,Ass1 |
| 4.150e-05 | -10.09 | HOUSTIS_ROS | MSigDB lists | HOUSTIS_ROS | 34 | 11 | 15632 | 1249 |
Gsr,Cp,Gclm,Txnrd1,Sod2,Txn1,Glrx,Sdc4,Prdx1,Hmox1,Hp |
| 4.150e-05 | -10.09 | GO_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND | MSigDB lists | GO_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND | 34 | 11 | 15632 | 1249 |
Bcl2a1d,Casp2,Casp3,Itgav,Bcl2l11,Bcl2a1b,Il1b,Bcl2a1a,Kitl,Il1a,Fas |
| 4.150e-05 | -10.09 | XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP | MSigDB lists | XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP | 34 | 11 | 15632 | 1249 |
Rin2,Isg20,Phlda1,Timp1,Asns,Hmga1,Slc4a7,Plau,Upp1,Arg2,Hmox1 |
| 4.150e-05 | -10.09 | GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 34 | 11 | 15632 | 1249 |
Tiparp,Pdgfrb,Arid5b,Rgs14,Csrnp1,Ptprj,Src,Pdgfc,Plat,Pdgfb,Jak2 |
| 4.161e-05 | -10.09 | regulation of gliogenesis | biological process | GO:0014013 | 154 | 25 | 20694 | 1406 |
Kdm4a,Lif,Il6,Mecp2,Tnf,Tspo,P2ry12,Hdac1,Ldlr,Etv5,Bmp2,Stap1,Crkl,Tlr2,Clcf1,Fas,Csf1,Lyn,Tnfrsf1b,Myc,Notch1,Hmga2,Il1b,Fubp1,Ptk2 |
| 4.196e-05 | -10.08 | regulation of vasoconstriction | biological process | GO:0019229 | 76 | 16 | 20694 | 1406 |
Htr2a,Pde5a,Cd38,Dusp5,Map2k1,Pdgfb,Ptafr,Hif1a,Edn1,Gja1,Cav1,Icam1,Dock4,Ahr,Ptgs2,Cx3cl1 |
| 4.206e-05 | -10.08 | signal transduction by protein phosphorylation | biological process | GO:0023014 | 192 | 29 | 20694 | 1406 |
Zfp36,Il18,Myc,Mlkl,Il1b,Ccr3,Mapkapk2,Ptk2,Itgav,Htr2b,Map3k6,Ccl5,Trib1,Ppm1l,Myd88,Map4k4,Ccl12,Map2k4,Map2k1,Kdr,Nek6,Ptger4,Syk,Mapkbp1,Tnf,Mdfic,Ripk2,Mul1,Map3k8 |
| 4.216e-05 | -10.07 | Phagosome | KEGG pathways | mmu04145 | 178 | 33 | 7931 | 713 |
Tap2,H2-T22,Tlr6,H2-Q4,Cd14,C1ra,Nox1,H2-Ab1,C3,Fcgr2b,H2-Eb1,Marco,H2-Q7,Olr1,Fcgr4,H2-T24,Fcgr1,Msr1,Tap1,Tlr2,Itgav,Thbs1,Dync1h1,Actb,Itga5,Pikfyve,Atp6v1d,Dync1i2,H2-T10,Tuba4a,H2-Q6,H2-M2,H2-Aa |
| 4.216e-05 | -10.07 | Phagosome | KEGG pathways | ko04145 | 178 | 33 | 7931 | 713 |
H2-Q4,Tlr6,H2-T22,Tap2,Cd14,H2-Eb1,C3,Fcgr2b,H2-Ab1,Nox1,C1ra,Fcgr1,H2-T24,Olr1,Fcgr4,H2-Q7,Marco,Itgav,Tlr2,Tap1,Msr1,Dync1h1,Thbs1,Tuba4a,H2-T10,Dync1i2,Atp6v1d,Itga5,Actb,Pikfyve,H2-Aa,H2-M2,H2-Q6 |
| 4.249e-05 | -10.07 | WORSCHECH_TUMOR_EVASION_AND_TOLEROGENICITY_DN | MSigDB lists | WORSCHECH_TUMOR_EVASION_AND_TOLEROGENICITY_DN | 14 | 7 | 15632 | 1249 |
Tor1aip2,Socs1,Tank,Irf1,Il10,Tlr6,Socs3 |
| 4.249e-05 | -10.07 | GO_RESPONSE_TO_MURAMYL_DIPEPTIDE | MSigDB lists | GO_RESPONSE_TO_MURAMYL_DIPEPTIDE | 14 | 7 | 15632 | 1249 |
Ripk2,Nod1,Nfkbia,Tnfaip3,Jag1,Nod2,Notch1 |
| 4.249e-05 | -10.07 | DAZARD_UV_RESPONSE_CLUSTER_G28 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G28 | 14 | 7 | 15632 | 1249 |
Gadd45b,Atf3,Cited2,Ier3,Ptgs2,Cxcl1,Cxcl2 |
| 4.249e-05 | -10.07 | GO_POSITIVE_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_BIOSYNTHETIC_PROCESS | 14 | 7 | 15632 | 1249 |
Nampt,Tlr9,Ccl12,Tlr2,Jak2,Kdr,Nod2 |
| 4.256e-05 | -10.06 | BIOCARTA_KERATINOCYTE_PATHWAY | MSigDB lists | BIOCARTA_KERATINOCYTE_PATHWAY | 46 | 13 | 15632 | 1249 |
Nfkbia,Tnf,Tnfrsf1b,Nfkb1,Traf2,Fos,Jun,Map2k1,Ets2,Prkce,Fas,Map2k4,Daxx |
| 4.256e-05 | -10.06 | KEGG_TYPE_I_DIABETES_MELLITUS | MSigDB lists | KEGG_TYPE_I_DIABETES_MELLITUS | 46 | 13 | 15632 | 1249 |
H2-Q7,H2-Ab1,Fas,Il12b,Il1a,Cd80,Il1b,H2-Eb1,Tnf,H2-Q4,H2-Q6,Cd86,H2-Aa |
| 4.256e-05 | -10.06 | SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | MSigDB lists | SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | 46 | 13 | 15632 | 1249 |
Junb,Tagln,Csrp1,Ltbp2,Cav1,Pdgfrb,Plod2,Edn1,St3gal5,Sdc2,Cebpd,Irf1,Cacnb3 |
| 4.257e-05 | -10.06 | GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_UP | 173 | 30 | 15632 | 1249 |
Ms4a6d,Slc43a3,Mthfd2,Azi2,Acsl1,Lyn,Rtn1,Trem1,Fam162a,Keap1,Acp2,Prkar2b,Adap2,Slc7a8,Lnpep,Inhba,Sap30,Csf1,Stxbp1,Me1,Plau,Cd83,Cd14,Swap70,Cyfip1,Rhbdf2,Txnrd1,Fcgr2b,Ctsc,Pnp2 |
| 4.265e-05 | -10.06 | regulation of lipid localization | biological process | GO:1905952 | 145 | 24 | 20694 | 1406 |
Syk,Hilpda,Ehd1,Ikbke,Il1a,P2ry2,Thbs1,Nfkbia,Msr1,Edn1,Ptch1,Itgav,Irs2,Lipg,Ttc39b,Ptpn2,Zc3h12a,Sirt1,Fabp3,Acsl5,C3,Kdm5b,Il1b,Nr1h3 |
| 4.277e-05 | -10.06 | GO_REGULATION_OF_DNA_BINDING | MSigDB lists | GO_REGULATION_OF_DNA_BINDING | 94 | 20 | 15632 | 1249 |
Ifi208,Ifi211,Irf4,Ifi203,Ifi213,Nfkbia,Txn1,Ifi209,Mndal,Jun,Ifi205,Jak2,Ifi207,Plaur,Lhx2,Lif,Hmox1,Mmp9,Ifi214,Ifi204 |
| 4.348e-05 | -10.04 | KARLSSON_TGFB1_TARGETS_DN | MSigDB lists | KARLSSON_TGFB1_TARGETS_DN | 190 | 32 | 15632 | 1249 |
Syne2,Met,Mmd,Wars,Smpdl3b,Psme2,Slc12a9,Nlgn2,Plat,Tnip1,Azi2,Arid5b,Grina,Ap3b1,Rin2,Mllt6,Dusp8,Slc44a1,Bbx,Stat3,Fut8,Dnaja1,Mtus1,Ezr,Enpp4,Slc48a1,Slc16a1,Nod1,F11r,Tpi1,Usp25,Tmem176b |
| 4.348e-05 | -10.04 | GSE43955_10H_VS_30H_ACT_CD4_TCELL_DN | MSigDB lists | GSE43955_10H_VS_30H_ACT_CD4_TCELL_DN | 190 | 32 | 15632 | 1249 |
P4ha1,Ankib1,Ccr1,Casp4,Lcn2,Ogfr,Plk2,Cnp,Zc3h12c,Sema3c,St3gal5,Ksr1,Pla2g7,Socs3,Il13ra1,Hp,Mtmr14,Tgfbi,Ldlr,Ikbke,Serpinb2,Clcn7,Trafd1,Rcl1,Dio2,Psip1,Spic,Traf2,Rab21,Sdc2,Mcoln2,Cd83 |
| 4.348e-05 | -10.04 | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_DN | MSigDB lists | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_DN | 190 | 32 | 15632 | 1249 |
Fut8,Myc,Cnot4,Tnf,Armcx6,Sod2,Arid5a,Sav1,Klf7,Crim1,Atf3,Mapkapk2,Csrnp1,Prnp,Fam133b,Socs1,Znrf3,Slc4a7,Nfkb1,Dcun1d3,Osm,Ptch1,Tax1bp1,Adam19,Rgs1,Agpat4,Pmepa1,Rnf19b,Phf6,Pim1,Map3k8,Nr4a3 |
| 4.358e-05 | -10.04 | GO_REGULATION_OF_LIPID_STORAGE | MSigDB lists | GO_REGULATION_OF_LIPID_STORAGE | 40 | 12 | 15632 | 1249 |
Ehd1,Tnf,Nfkbia,Nfkb1,Itgav,Msr1,Ptpn2,Il6,Sirt1,C3,Zc3h12a,Nr1h3 |
| 4.380e-05 | -10.04 | extracellular space | cellular component | GO:0005615 | 1616 | 150 | 20747 | 1409 |
Ccl3,Serpinb6b,Cxcl3,Ifna2,Raet1e,Lif,H2-T22,Tnfsf9,Vasn,Cpd,Cd86,Ldlr,Ifna5,Csf3,Flrt3,Il27,Tnfsf8,H2-T24,S100a8,Il15,Tnfsf10,H2-Q6,Il10,Cp,H2-Q4,Pf4,Sele,Ccr3,Cnp,Serpinb2,Lox,Lcn2,Saa3,Vcan,Serpinb9,Pdgfc,H2-Q7,Cst7,Tnfsf14,Cxcl14,Vegfc,Smpdl3b,Tsku,Ifna1,Ltbp2,H2-T10,Col11a2,Fam20c,Tnfsf15,H2-M2,Cx3cl1,Col4a2,Rnaset2a,Kitl,Icam1,Ccl9,Agrn,Serpina3g,Msr1,Gdf15,Plau,Hilpda,Spn,Il18bp,Sema3c,Cxcl1,Cd274,Cd14,Angpt1,Mmp9,Edn1,Ctsc,Il1a,Mmp25,Kmo,Rnaset2b,Itga4,Mmp14,Glipr2,Serpina3f,Procr,C3,Ccl8,Mmp13,Cxcl2,Il12b,Flrt2,Il1rn,Pgk1,Slpi,Fabp3,Ccl7,Col27a1,Cd40,Sema4c,Tgfbi,F10,Il1b,Ccl22,Tnfsf4,Lipe,Cd180,Acpp,H60b,Lrp8,Cxcl9,Htra1,Axl,Ccl2,Inhba,Tnf,Flt1,C1rl,Pla2g7,Pdgfb,Asah2,Clcf1,Ifnb1,Vcam1,Osm,Il18,Cxcl11,Lipg,Ifna4,Nos2,Plod3,Il4ra,Hp,Serpinb9b,Csf1,C1ra,Ccl12,Tnc,Bmp2,Ifna6,Fas,Met,Thbs1,Gsdmd,Sema4a,Col18a1,Plat,Timp1,Serpine1,Nampt,Il6,Ccl5,Ebi3,Cxcl10,Ccl4 |
| 4.404e-05 | -10.03 | GSE3565_DUSP1_VS_WT_SPLENOCYTES_DN | MSigDB lists | GSE3565_DUSP1_VS_WT_SPLENOCYTES_DN | 165 | 29 | 15632 | 1249 |
Rab3ip,Rras2,Sell,Rtp4,Etv3,Rhoh,Evl,Treml2,Tnfsf8,Peli1,Fchsd2,Myc,Ikzf1,Mdn1,Plac8,Ikbke,Acvr1b,Filip1l,Cd69,Dgka,Tlr1,Ext1,Sipa1l1,Cnp,Dusp6,Sesn3,Map4k4,Ccne1,Mthfd1l |
| 4.410e-05 | -10.03 | MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN | MSigDB lists | MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN | 59 | 15 | 15632 | 1249 |
Ifit3b,Pttg1,Tnfaip2,Gclc,Nfkb2,Kitl,Hspa1a,Lcn2,Bcl6,Ifit3,Arhgef3,Sod2,Spint2,Slpi,Phlda1 |
| 4.410e-05 | -10.03 | GO_CELLULAR_RESPONSE_TO_IONIZING_RADIATION | MSigDB lists | GO_CELLULAR_RESPONSE_TO_IONIZING_RADIATION | 59 | 15 | 15632 | 1249 |
Ifi213,Atm,Ifi205,Ifi209,Mndal,Ifi208,Ifi211,Ifi203,Sirt1,Tlk2,Egr1,Ifi214,Ifi204,Cdkn1a,Ifi207 |
| 4.428e-05 | -10.02 | protein domain specific binding | molecular function | GO:0019904 | 797 | 85 | 20217 | 1400 |
Myd88,Casp8,Sqstm1,Rapgef2,Mecp2,Pttg1,Etv6,Ripk2,Prkce,Lyn,Bmp2,Nod1,Nod2,Mitd1,Vasp,Sirt1,Gja1,Vrk2,Gpsm2,Ezr,Wars,Dock4,Tnks1bp1,Prkar2b,Egr2,Atp2b4,Irgm2,Aida,Sh3bgrl2,Plscr1,Il1b,Plaur,Hif1a,Ptk2,Sdc2,Gng12,Spn,Fzd1,Lpar1,Hhex,Stxbp1,Ikzf1,Rhoq,Bcl2a1a,Cd40,Pou2f2,Src,Bcl2a1b,Cacybp,Hspa2,Crim1,Hap1,Cenpj,Syk,Ets2,Dbnl,Hcls1,Jun,Bcl2a1d,Casp2,Adgrl2,Casp1,Reps1,Mpp7,Adam19,Mafk,Cacna1d,Nck1,Plekha2,Dnaja1,Irs2,Keap1,Mdm2,Cited2,Casp4,Ikbkg,Hspa1a,Apba1,Jak2,Pmepa1,Evl,Fut8,F11r,Errfi1,Hdac1 |
| 4.428e-05 | -10.02 | regulation of tumor necrosis factor secretion | biological process | GO:1904467 | 33 | 10 | 20694 | 1406 |
Arid5a,Ddx58,Cx3cl1,Tlr2,Tlr6,Fzd5,Zc3h12a,Arg2,Ifih1,Ptger4 |
| 4.446e-05 | -10.02 | IVANOVA_HEMATOPOIESIS_MATURE_CELL | MSigDB lists | IVANOVA_HEMATOPOIESIS_MATURE_CELL | 251 | 39 | 15632 | 1249 |
Mthfd2,Acsl1,Fpr1,Grina,C3,Dck,Endod1,Smox,Cpeb4,Tcea1,Thbs1,Rbms1,Gtpbp2,Daam1,Asns,Slc7a8,AA467197,Rhou,Stx11,Trim56,Rnf19a,St3gal5,Ampd3,Fgr,Sertad3,St3gal6,Usp25,Tlr6,Mxd1,Slc16a1,Cd14,P2ry13,Slc25a37,Klf3,Pcx,Cpd,Rffl,D1Ertd622e,Nr3c1 |
| 4.471e-05 | -10.02 | MODULE_94 | MSigDB lists | MODULE_94 | 342 | 49 | 15632 | 1249 |
Bcl2a1d,C1ra,Sele,Egr2,Tpst1,Klhl25,Rnd1,Stat2,Apba1,Ch25h,Ppp2r3a,Zfp324,Pdlim7,Hopx,4930523C07Rik,Abcc4,Keap1,Dio2,Gng12,Il15ra,Bcl2a1a,Cxcl10,Hmox1,Dusp4,Dusp2,Igsf6,Rai14,Gclm,Jun,Bcl2a1b,Aoah,Ppfibp1,Me1,Atp2b4,Cdc42ep2,Atf3,Rasgrp1,Pla2g7,Nfkbib,Procr,Rims3,Irf8,Cav1,Ccne1,Pfkl,Lhx2,Ier3,Ell2,Egr3 |
| 4.473e-05 | -10.01 | intracellular organelle part | cellular component | GO:0044446 | 7048 | 547 | 20747 | 1409 |
Spata13,Psip1,Etv3,Atf3,Gfi1,Rmdn3,Tgtp1,Optn,Pik3r5,Alas1,Fosb,Ak4,Glipr2,Dhrs9,Aff1,Cdkn1a,Bbx,Cox17,Rab19,Myo10,Map2k1,Zfp281,Slc37a3,Sik3,Tpx2,Ier2,P4ha1,Rubcnl,Acsl5,Oas1b,Jarid2,Ubr4,Zc3h12a,Gsdmd,Irf7,Tfec,Nmi,Tra2a,Tgtp2,Rap1gap2,Rai14,Fas,Klf3,Cited2,Brd2,Klf6,Intu,Osbpl3,Mapkapk2,Atp6v1d,Tpst1,Aim2,Plk3,Rab3ip,Hspa1b,Parp3,Snx2,Flnb,Bcl2a1d,Irf4,Dnajb4,Nampt,Sbds,Treml4,Cept1,Fubp1,Nsd3,Pcgf5,Hap1,Irf2,Samhd1,Cenpj,Nes,Zeb1,Cyth3,Ankrd17,Dync1i2,Oasl2,Tmod3,Jun,Irf1,Noc4l,Ldlr,P4ha2,Cdyl,Klf2,Etnk1,Cpd,Mafk,Snn,Ccdc86,Wdr59,Ccdc88b,Bcor,Pou2f2,Kdm5b,Agtrap,Arl5b,Batf,Tasor2,Pml,Tspo,Gm5431,Fos,Dse,Resf1,Ptges,Yju2,Rbl1,Magohb,Cop1,Clcn7,Bcl2a1b,Gm12185,Txnrd1,H2-Eb1,Znfx1,Rrbp1,Jak2,Sap30,Egr2,Prkce,Dtx3l,Nxf1,Egr1,Ciita,Top3a,Gch1,Hsph1,Hspa2,1600014C10Rik,Tma16,Rrs1,Daam1,Phf11b,Fcho2,Mx1,Phf11a,Etv5,Ikzf1,AA467197,Sp100,Ctsc,Nr4a1,Snapc1,Stk40,Ch25h,Kdm6b,Rel,Shfl,Olr1,Tgfbi,Fscn1,Itpkc,Rgs14,Hck,Arid4a,N4bp1,Rhoq,Pmepa1,Ranbp2,Nlrc5,Phlpp1,Pim1,Kmo,Stat5a,Fut8,Acsl1,Triobp,Kif3c,Rilpl1,Mcm10,Riox2,Mdm2,Traf5,Acpp,Aldh1b1,Birc3,Slc2a1,Mcm6,Aebp2,Srgn,Max,Rffl,Ednrb,Ets2,Dnajb2,Ero1l,Tnip1,Trip10,Ahrr,Slc9a1,Notch2,Ptger4,Sec24a,Fgr,Atp11b,Mtdh,Htr2b,Polr2g,Malt1,Ptk2,Tor1aip1,Igtp,Nfkb1,Mgat1,Rtn1,Rac3,Marcks,Hivep2,Sphk1,Atp11a,Tuba4a,Golga3,Hinfp,Dusp4,Prdm9,Slc25a22,Rnf139,Parp10,Glrx,H2-Q6,Trim21,Tap2,Stxbp1,Uchl1,Plscr1,Setdb2,Abcc4,Ell2,Rpgrip1l,Sqstm1,H2-Q7,Pdlim7,Vrk2,Pikfyve,Tcea1,Ifi203,Gbp2,Ahr,Parp9,Serpinb9,Ifi208,Mxd1,Iigp1,Tmem67,Mapkbp1,Tlk2,Psd,9930111J21Rik1,Gm4841,Ifi211,Ccnd1,Cox18,Ifi205,Rnaset2a,Sertad3,Ccnd2,Relb,Slc48a1,Ep400,Psma6,Dpy19l1,Ass1,Dennd1b,Pigv,Smox,Hif1a,Lpcat2,Edn1,Hcls1,Med13,Cdkn2d,Hilpda,Cenpe,Palld,Oasl1,Hspa1a,Pkp4,Nr1h3,Slc25a12,Sema4c,Kif5c,Hdac1,Bcl2a1a,Clmp,Ric1,Traf2,Rap2c,Ppp2r5a,Asap3,Mul1,Sco1,Gpsm2,Casz1,Nfkbiz,Nr3c1,Aftph,Cutc,Smg7,Mx2,Pcx,Tulp3,Ift22,Phf6,Pdk3,Prpf4,Crbn,Tnks1bp1,Arid5a,Eef1e1,Itpr1,Taf4b,Sp140,Ciapin1,Ifi207,Higd1a,Plod3,Gramd1a,Myc,Cebpd,Rab32,Mndal,Cycs,Rgs3,Dst,Zyx,Cd38,Rnf34,Crkl,Snx10,Ift57,Ifi209,Mecp2,Ppp4r2,Cnn2,Cep350,Mdn1,Il15,Rapgef5,Ifi214,Psmb6,Rtn2,Clic4,Cx3cr1,Fam111a,Ifi47,Junb,Nlrp3,Bnip3,Syne2,Klf8,Sirt1,Dr1,Ptpn2,Kif9,Oas2,F830016B08Rik,Rcl1,Rhbdf2,Mpp7,Armcx6,Dcp2,Tle3,Chmp4b,Wdr43,Trib3,Cnp,Ppp1r15a,Slc25a37,Cdk5r1,Spry2,Phlda1,Hmgn3,Ikbkg,Asf1a,Slc29a3,Bcorl1,Abtb2,Maml2,Ifi204,Phf11c,Irf8,Rgcc,Mefv,Vps54,Dtx2,Myadm,Gk,Prdx1,Mtus1,Radx,Atm,Sh3bgrl2,Src,Stap1,Mark2,Keap1,Trim14,Pde4b,Myo1b,Upp1,Parp11,Tcf4,Plekha5,Slc16a3,Prkar2b,Gng12,Dyrk2,Jmjd6,Dync1h1,Ext1,Hk2,Ap3b1,Gpc1,Timeless,Stat1,Tomm70a,Prdx5,Adar,Stx6,Phf11d,Hmox1,Mcoln2,Rnaset2b,Daxx,Gpd2,Lyn,Sec24b,Lnpep,Nfkbie,Procr,Nek6,Med21,Mid1,Mier3,Katna1,Abcc1,Slc16a1,Rars,Gem,Plagl1,Spen,Tpm4,Tent4a,Lrp8,Slc25a25,Uaca,Prpf38a,Pstpip2,Tdrd7,Tap1,Rbpms,Psme1,Tor3a,Ifi213,Ehd1,Dusp2,Serp1,Gsap,Socs1,Dock10,Sod2,Bcl6,Tapbp,Oas1a,Arl4a,Vcam1,Hat1,Oas1g,Cacybp,Micall2,Smc5,Morc3,Zhx2,Dusp16,Bcl2l11,Whamm,Dbnl,Carmil1,Irgm2,Rabgef1,Isg20,Anp32a,Mdfic,Mrpl52,Casp8,Actb,Arl5c,Plekhg1,Bcl9,Rab9,Psme2,Slc15a3,Tmtc2,Spire1,Sgms2,Gja1,Tmem178,Cgas,Slc30a1,Gm4951,H3f3b,Pfkfb3,Pnpt1,Oas3,Lap3,Mppe1,Hmga2,H2-Q4,Ccne1,Pbx1,Kdm4a,Sinhcaf,Etv6,Stat3,Hk1,Pgap2,Trim13,Sass6,Plekhn1,Rab21,Slc44a1,Lnpk,Ppm1k,Dock4,Rsad2,Irgm1,Cep85l,Kat2b,Cav1,Ago3,Tut7,Rbbp8,Hmga1,Vezt,Prnp,Ezr,Cd274,Agpat4,Adora2a,Plpp3,Mcmbp,Adap2,Ikbke,Plk2,Rab10 |
| 4.480e-05 | -10.01 | GO_NEGATIVE_REGULATION_OF_GROWTH | MSigDB lists | GO_NEGATIVE_REGULATION_OF_GROWTH | 216 | 35 | 15632 | 1249 |
Pml,Cdkn2d,Hif1a,Mul1,Sertad3,Cdk5r1,Sav1,Crlf3,Pnpt1,Plac8,Tnf,Sqstm1,Bcl6,Eno1,Ifrd1,Acvrl1,Sema4c,Ptprj,Ptk2,Gng4,Acvr1b,Adrb2,Sema4a,Il12b,Dcbld2,Cdkn1a,Gja1,Dcun1d3,Il10,Sema3c,Irf8,Ptch1,Sh3bp4,Inhba,Sirt1 |
| 4.485e-05 | -10.01 | WWE_dom_sf | interpro domains | IPR037197 | 11 | 6 | 19984 | 1430 |
Parp11,Parp14,Dtx2,Parp12,Zc3hav1,Tiparp |
| 4.561e-05 | -10.00 | GO_NEGATIVE_REGULATION_OF_SECRETION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_SECRETION | 182 | 31 | 15632 | 1249 |
Rhbdf2,P2ry12,Ezr,Tnf,Rsad2,Il6,Rab11fip1,Edn1,Slc30a1,Cx3cl1,Nlrp3,Nr1h3,Cd74,Pml,Lif,Abr,Angpt1,Notch1,Pim3,Cd34,Osm,Il10,Rabgef1,Inhba,Stxbp3,Hmox1,Zc3h12a,Tnfsf4,Ptger4,Il1b,Pfkl |
| 4.561e-05 | -10.00 | GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_UP | MSigDB lists | GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_UP | 182 | 31 | 15632 | 1249 |
Mxd1,Atf3,Fas,Batf,Pde3b,Tnfrsf14,Ahr,Rapgef5,Rab9,Slc15a3,Glipr2,Acvrl1,Ebi3,Nsmaf,Ttc39b,Gng12,Pkp4,Vrk2,Plek,Pdk3,Junb,Tnfrsf1b,Rel,Lcp2,Zc3h12c,Cd86,Casp4,Atxn7l1,Etv6,Maff,Hk2 |
| 4.561e-05 | -10.00 | GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_UP | MSigDB lists | GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_UP | 182 | 31 | 15632 | 1249 |
Tnfrsf1b,Nfkb1,Txn1,Il18rap,Nsmaf,Acsl1,Rcn1,Dusp5,Ldha,Psmb6,Egr3,Il1b,Pgk1,Adam19,Ccl4,Idi1,Cflar,Snapc1,Polr2g,Eno1,Homer1,Srm,Apobec3,Hivep2,Tnf,Ccdc86,Ggct,Palld,Tpi1,Hinfp,Rras2 |
| 4.561e-05 | -10.00 | GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP | MSigDB lists | GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP | 182 | 31 | 15632 | 1249 |
Phlpp1,Fchsd2,Peli1,Il6,Cp,Gpr35,Fut8,Nr3c1,Bcl6,Jun,Gpr18,Cd38,Pde3b,Rras2,Pikfyve,Sell,Phip,Vasp,Tlr1,Akt3,Icosl,Osm,Lnpep,Pde4b,Birc3,4930523C07Rik,Rbms1,Lyn,Ms4a6d,Pim2,Ebi3 |
| 4.561e-05 | -10.00 | GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_DN | 182 | 31 | 15632 | 1249 |
Rgs3,Tnfrsf14,Cd38,Psmb10,Nr1h3,Hhex,Aim2,Abr,Dtnb,Fgl2,Ctsc,Mgat1,Psmb9,Gypc,Ifit1bl1,Stat5a,Prkar2b,Acp2,Ikbke,Prkx,Gpd2,Ptgir,Stat1,Larp1,H2-Ab1,Hk2,Rasgrp1,Spint2,Alas1,P4ha1,Ifit1bl2 |
| 4.565e-05 | -9.99 | reproductive system development | biological process | GO:0061458 | 433 | 52 | 20694 | 1406 |
Plekha5,Bcl2l11,Src,Map2k1,Atm,Lif,Pdgfb,Hif1a,Htra1,Ptgs2,Nos2,Serpinb6b,Tiparp,Sirt1,Axl,Hmga2,Notch1,Crkl,Gja1,Itgav,Spint2,Inhba,Ccnd1,Ahr,H3f3b,Prdm1,Angpt1,Met,Il10,Pla2g4a,Plaur,Cited2,Kdr,Tnc,Arid4a,Socs3,Kitl,Stat5a,Itga4,Arid5b,Insl6,Fzd5,Junb,Kdm5b,Igf1r,Fndc3a,Vcam1,Birc2,Serpine1,Notch2,Nupr1,Icam1 |
| 4.582e-05 | -9.99 | purine ribonucleoside binding | molecular function | GO:0032550 | 361 | 46 | 20217 | 1400 |
Rhof,Gbp2b,Gbp8,Arl4a,Rab9,Tgtp1,Gbp9,Rnd3,Nkiras1,Irgq,Rap2c,Rhou,Gmppb,Rhoc,Rab10,Gna15,Rras2,Iigp1,Gem,Mx1,Samhd1,Arl5c,Rnd1,Rab20,Tuba4a,Ciita,Gbp7,Rab21,Ehd1,Rhoq,Hcar2,Rab19,Gtpbp2,Arf4,Gch1,Irgm1,Rac3,Ak4,Gbp2,Arl5b,Cgas,Rab32,Mocs1,Ift22,Gbp3,Rhoh |
| 4.595e-05 | -9.99 | protein ADP-ribosylation | biological process | GO:0006471 | 27 | 9 | 20694 | 1406 |
Parp3,Parp9,Parp14,Parp11,Parp10,Parp8,Tiparp,Arf4,Parp12 |
| 4.595e-05 | -9.99 | programmed necrotic cell death | biological process | GO:0097300 | 27 | 9 | 20694 | 1406 |
Casp1,Birc3,Fas,Ripk3,Tnf,Tlr3,Mlkl,Birc2,Traf2 |
| 4.605e-05 | -9.99 | TNF signaling | REACTOME pathways | R-MMU-75893 | 37 | 12 | 8608 | 757 |
Traf1,Tab2,Nsmaf,Tnfaip3,Birc2,Tax1bp1,Traf2,Rnf31,Tnf,Birc3,Ikbkg,Casp8 |
| 4.613e-05 | -9.98 | GO_KINASE_BINDING | MSigDB lists | GO_KINASE_BINDING | 564 | 72 | 15632 | 1249 |
Plek,Ppp1r15a,Fzd5,Map2k1,Pdgfrb,Ptprj,Ldha,Trib3,Nr4a3,Ptafr,Src,Lipe,Lrp4,Rgs14,Traf2,Slc2a1,Stat3,Rffl,Ccnd1,Errfi1,Mlkl,Acvrl1,Hif1a,Trim12c,Fgr,Socs1,Gys1,Daxx,Mvp,Tnfaip3,Ccne1,Cav1,Cenpj,Ksr1,Zfp36,Rictor,Sirt1,Ptk2,Trib1,Cacnb3,Jak2,Tax1bp1,Tnip1,Hcls1,Pfkl,Vrk2,Prkar2b,Ezr,Syk,Sqstm1,Itgav,Ptpn2,Dock4,Spry2,Stap1,Dusp2,Ppp2r5a,Nod2,Fas,Nck1,Nek6,Stxbp1,Cdkn2d,Ccnd2,Kat2b,Cdk5r1,Tpx2,Irs2,Sdc4,Pde3b,Spred1,Angpt1 |
| 4.615e-05 | -9.98 | FORTSCHEGGER_PHF8_TARGETS_UP | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_UP | 225 | 36 | 15632 | 1249 |
Igf1r,Dusp16,Mthfd2,Dnajb4,Smc5,Hmox1,Ptprj,Stx6,Rab10,Ddit4,Lmo4,Fubp1,Fzd5,Asns,Pdgfc,Ncoa7,Slc16a1,Gclc,Bmp2,Lrp8,Nupr1,Hlx,Nqo1,Lztfl1,Dusp2,Ctsc,Phgdh,Serp1,Cited2,Ptpn2,Tspan3,Acpp,Itpr1,Bcl2l11,Slc7a11,Nr4a1 |
| 4.632e-05 | -9.98 | antigen binding | molecular function | GO:0003823 | 60 | 14 | 20217 | 1400 |
H2-T10,H2-Aa,H2-T22,Cd40,Ep400,H2-M2,H2-Ab1,H2-T24,Tap1,H2-Q7,H2-Q4,Tap2,Itga4,H2-Q6 |
| 4.654e-05 | -9.98 | TAKAO_RESPONSE_TO_UVB_RADIATION_DN | MSigDB lists | TAKAO_RESPONSE_TO_UVB_RADIATION_DN | 102 | 21 | 15632 | 1249 |
Ifi203,Cebpd,Slc39a14,Zfp36,Ifi208,Ifi211,Rbbp8,Ifi205,Ifi209,Rrs1,Mndal,Ifi213,Tnfaip3,Vrk2,Ifi207,Esd,Cd164,Nfkb2,Ifi214,Ccnd2,Ifi204 |
| 4.654e-05 | -9.98 | CRX_DN.V1_DN | MSigDB lists | CRX_DN.V1_DN | 133 | 25 | 15632 | 1249 |
Trim13,Prdm1,Nupr1,Egr1,St3gal3,Col4a2,Gng11,Timp1,Glipr2,Cebpd,Rai14,Map3k8,Socs3,Dusp16,Cdkn1a,Frmd6,Plat,Lad1,Plod2,Junb,Nfkb1,Sh3bp4,Tmem176a,Ksr1,Fabp7 |
| 4.663e-05 | -9.97 | GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION | 66 | 16 | 15632 | 1249 |
Htr2b,Kdr,Bmp2,Hif1a,Egr3,Sirt1,Rictor,Acvrl1,Pdgfb,Nrp2,Ccr3,Cav1,Jun,Stat5a,Nr4a1,Ccl12 |
| 4.663e-05 | -9.97 | GO_NEGATIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 66 | 16 | 15632 | 1249 |
Nfkbia,Txn1,Il10,Psmd10,Nfkbib,Fzd1,Nfkbie,G3bp2,Zc3h12a,Dyrk2,Parp10,Nfkbil1,Nlrp3,Mdfic,Keap1,Angpt1 |
| 4.663e-05 | -9.97 | KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY | MSigDB lists | KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY | 66 | 16 | 15632 | 1249 |
Acsl5,Jak2,Socs3,Irs2,Acsl1,Stat3,Akt3,Nfkbib,Nfkbie,Nfkbia,Tnf,Tnfrsf1b,Nfkb1,Ikbkg,Traf2,Slc2a1 |
| 4.682e-05 | -9.97 | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | MSigDB lists | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | 80 | 18 | 15632 | 1249 |
Trem1,Angpt1,Olr1,Pf4,Slc16a1,F11r,Sell,Lyn,Itga5,Slc7a5,Itgal,Cav1,Slc7a8,Src,Spn,Slc7a11,Slc16a3,Itgav |
| 4.727e-05 | -9.96 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | 964 | 111 | 15632 | 1249 |
Plk3,Pdgfc,Rgs3,Lipg,Gnb4,Homer1,Abcc5,Usp53,Phldb1,Ddhd1,Cers6,Ccng2,Tlk2,Mecp2,Itgb8,Sat1,Parp3,Ppp2r2a,Pkp4,Nfkb2,Ralgds,Pcdh7,Col11a2,Flrt2,Ccl5,Pde4b,Sh3bp4,Arl5b,Pdlim7,Stxbp3,Tmeff1,Wdfy1,Arl4a,Slc30a1,Ubash3b,Sdc1,Ahr,Slc48a1,Sgcb,Ets2,D16Ertd472e,Gadd45b,Spsb1,Bnip3,Map2k4,Lpar1,Cacnb3,Dnajb4,Lrrc8c,Col27a1,Ust,Cd82,Jak2,Rbms1,Plekhg1,Mfap3l,Zscan29,Rictor,Rtn2,Nfkbib,Csf1,Apba1,Mxd1,Notch1,Nod1,Bfar,Hspa1a,Ttc39c,Lrp4,Axl,Ehd1,Lztfl1,Kdm5b,Rffl,Dusp8,Kif3c,Mob3b,Fmnl2,Elmod2,Cnp,Sesn3,Slc31a2,Dgka,Sass6,Ppm1l,Xrn1,Prnp,Nmral1,Atf3,Dock4,Jun,Fos,Tet2,Ezr,Samd9l,Sdc2,Tra2a,Slc44a1,Peli1,Tgs1,Irgm2,Stat1,Socs3,Nlgn2,Agpat4,Actb,P4ha1,Flnb,Ep400,Htra1,Akt3 |
| 4.743e-05 | -9.96 | GO_POSITIVE_REGULATION_OF_AUTOPHAGY | MSigDB lists | GO_POSITIVE_REGULATION_OF_AUTOPHAGY | 73 | 17 | 15632 | 1249 |
Sqstm1,Plk2,Trim21,Bnip3,Sh3bp4,Sirt1,Zc3h12a,Pim2,Ripk2,Mtdh,Larp1,Mefv,Adrb2,Trim13,Hif1a,Kdr,Nod1 |
| 4.759e-05 | -9.95 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | 174 | 30 | 15632 | 1249 |
Stx6,Parp12,Flnb,Irf8,Atm,Snx10,Prkar2b,Sp110,Ap3m2,Zcchc2,Notch2,Dek,Rsbn1,Gca,Dnajb4,Itga9,Pik3cd,Ebi3,Ptprj,Rab11fip1,Katna1,Ets2,Slc25a37,Morc3,Myo10,Cd83,Traf5,Pikfyve,Nlrp3,Ddx60 |
| 4.759e-05 | -9.95 | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN | 174 | 30 | 15632 | 1249 |
Ncoa7,Irak3,Cd34,Spata13,Rab19,Rtp4,Ifih1,Evl,Gsr,Mid1,P2ry12,Pmepa1,Nfil3,Abcc1,Dnajb2,Odc1,Chic2,Pdzd11,Ell2,Stat1,Egln3,Trim26,Ppp4r2,Klf2,Plod2,Pdk3,Tor3a,Tshz1,Tuba4a,Card6 |
| 4.774e-05 | -9.95 | ZHANG_TLX_TARGETS_36HR_UP | MSigDB lists | ZHANG_TLX_TARGETS_36HR_UP | 208 | 34 | 15632 | 1249 |
Myo10,Tap1,Fbxo4,Ccnd2,Upp1,Slco3a1,Sphk1,Stxbp1,Glipr2,Tapbp,Gadd45g,Sat1,Dusp8,Cited2,Jun,Gadd45b,Nr4a1,Slc7a11,Cdkn1a,Keap1,Sp110,Ralgds,Nfkb2,Grina,Rnf145,Acsl1,Parp3,Itga5,Srxn1,Ddit4,Csf1,Btg2,Scn1b,Ogfr |
| 4.799e-05 | -9.94 | NABA_MATRISOME_ASSOCIATED | MSigDB lists | NABA_MATRISOME_ASSOCIATED | 675 | 83 | 15632 | 1249 |
Timp1,Tnf,P4ha2,Insl6,Cst7,Plod3,Tnfsf8,Il1a,Lif,Pdgfc,Ifna2,Ccl3,Crlf3,Bmp2,Lgals9,Serpine1,Osm,Ccl5,Gdf15,Inhba,Csf3,Mmp13,Cxcl2,Pdgfb,Tnfsf15,Ifna6,Clec5a,Serpinb9,Il18,Cxcl10,Lox,Il12b,Clec4d,Vegfc,Pf4,Il1b,Il1rn,Cxcl1,Kitl,Tnfsf10,Serpinb2,Plat,Ccl12,Sdc2,Cxcl14,Ifna5,Ifnb1,Ctsc,Ccl2,Il6,Mmp14,Ccl22,Sdc1,Cx3cl1,Angpt1,Ifna1,Il15,F10,Plau,Sdc4,Clec4e,Gpc1,Tnfsf14,Sema3c,Il10,Plod2,Clec4n,S100a8,P4ha1,Egln3,Csf1,Slpi,Htra1,Mmp25,Sema4a,Sema4c,Tnfsf4,Ebi3,Mmp9,Clcf1,Ccl4,Fam20c,Adam19 |
| 4.817e-05 | -9.94 | response to inorganic substance | biological process | GO:0010035 | 456 | 54 | 20694 | 1406 |
Nr4a1,Pla2g4a,Ppp1r15b,Cp,Tnfsf4,Slc30a1,Prdx1,Mt2,Il1a,Daxx,Jun,Sod2,Kdr,Mecp2,Atp2b4,Selenow,Kdm6b,Fosb,Pdgfrb,Nqo1,Junb,Bnip3,Slc25a12,Fas,Hvcn1,Homer1,Clic4,Ass1,Lcn2,Prnp,Src,Mt1,Timeless,Thbs1,Fos,Cflar,Traf2,Il6,Hp,Axl,Zc3h12a,Mmp9,Sirt1,Nr4a3,Ripk3,Hmox1,Cav1,Tnfaip3,Ptch1,Itgav,Lrp11,Casp3,Slc30a4,Sphk1 |
| 4.832e-05 | -9.94 | GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN | 191 | 32 | 15632 | 1249 |
Sav1,Mdfic,Dnase1l3,Prdm1,H2-Q7,Magohb,Lrp8,Irf4,Casp3,Slc15a3,Cxcl14,Dusp4,H2-Q4,Casp1,Cyfip1,H2-Q6,Pgk1,Cdkn1a,Casp7,Serpinb9,Sap30,Pdss1,Phlda1,Plscr1,Trip13,Hk2,Stx11,Psat1,Ccne1,Tnfrsf1b,Irf8,Gem |
| 4.832e-05 | -9.94 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN | 191 | 32 | 15632 | 1249 |
Tpi1,Ccl22,Gmppb,Traf1,Socs1,Batf,Tap1,Stat5a,Homer1,Cd40,Rbbp8,Irf4,Slc15a3,Ly75,Cish,Etnk1,Psmb6,Stat1,Il13ra1,Ak4,Slc43a3,Rcn1,Ier3,Il15ra,Stip1,Keap1,Psat1,Txn1,Cd86,Alas1,Wars,Slc39a14 |
| 4.832e-05 | -9.94 | GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP | MSigDB lists | GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP | 191 | 32 | 15632 | 1249 |
Inpp1,Nr4a3,Lyn,Ell2,Kctd12,Snx2,H2-Aa,Cnn3,Casp4,Irf8,Myadm,Slc4a7,Eif4g2,Hck,Ciita,Crlf3,Sell,Il4ra,Ccl22,Upp1,Cd74,Plk3,C1ra,Il4i1,Rhoq,Fcgr2b,Bcl6,Cd40,Tcf4,Mgat1,Syk,Hivep2 |
| 4.832e-05 | -9.94 | GSE20366_TREG_VS_TCONV_DN | MSigDB lists | GSE20366_TREG_VS_TCONV_DN | 191 | 32 | 15632 | 1249 |
Gclc,Slamf7,Gng11,Sgk3,Olr1,Rab3ip,Tmem176b,H2-Q7,Nxf1,Rai14,Abcb1a,Cers6,Triobp,Parp8,H2-Q4,Acpp,H2-Q6,Gpr18,Parp3,Pim2,Smox,Rnf19b,Sema4a,Gpd2,Asb13,Btg2,Rap1gap2,Rnf19a,Sesn3,Casp4,Ppm1k,Tnfsf14 |
| 4.832e-05 | -9.94 | GO_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE | MSigDB lists | GO_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE | 191 | 32 | 15632 | 1249 |
Pdpn,Il6,Gsr,Spn,Tnf,Itgav,P2ry12,Cd40,F10,Cd34,Cd83,Cd80,Cd14,Tnfrsf14,Fas,Cd74,Icam1,Sdc1,Sell,Il12rb1,Cd69,H2-Eb1,Ccr1,Cd86,Cd274,Vcam1,Ldlr,Tmem123,Thbs1,Itga5,Il2rg,Cxcl10 |
| 4.887e-05 | -9.93 | regulation of smooth muscle cell migration | biological process | GO:0014910 | 85 | 17 | 20694 | 1406 |
Src,Plau,Il18,Pdgfrb,Mdm2,Myc,Ptk2,Ptger4,Pdgfb,Dock4,Nr4a3,P2ry2,Egr1,Ccl5,Lpar1,Trib1,Serpine1 |
| 4.937e-05 | -9.92 | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP | 166 | 29 | 15632 | 1249 |
Sav1,Rras2,Traf5,Rhoh,Il4ra,Stap1,Fchsd2,Myc,Ift57,Sp140,Ezr,Swap70,Itpr1,Gpr18,Adam19,Zhx2,Sp110,Pim2,Cd200,Il2rg,Kcna3,Odc1,Zeb1,Rasgrp1,Cd69,Snx2,Atm,Birc3,Plekha2 |
| 4.937e-05 | -9.92 | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_UP | MSigDB lists | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_UP | 166 | 29 | 15632 | 1249 |
Ahr,Atp11b,Tnks1bp1,Crim1,Sell,Errfi1,Pde1b,Tnfsf8,Mdn1,Fcgr2b,Otud1,Pik3r5,Bcl2l11,Ppp1r14b,Cx3cr1,Klf3,Nr4a1,Rcsd1,Rnf145,Socs3,Cd55,Dgkh,Pou2f2,Dgka,Rap1gap2,Smpdl3b,Usp12,Klf2,Map4k4 |
| 4.939e-05 | -9.92 | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | 110 | 22 | 15632 | 1249 |
Calcrl,Pfkfb3,Vcam1,1600014C10Rik,Pnpt1,Pdgfc,Pgk1,Map3k6,Stat5a,Lrp4,Pid1,Slc2a1,Lmo4,Bcl6,Pla2g4a,Bnip3,Errfi1,Egln3,Cebpd,Cxcl14,Maff,Gadd45g |
| 4.940e-05 | -9.92 | DAZARD_RESPONSE_TO_UV_NHEK_UP | MSigDB lists | DAZARD_RESPONSE_TO_UV_NHEK_UP | 217 | 35 | 15632 | 1249 |
Hspa2,Cox17,Il6,Jun,Cited2,Fos,Itpr1,Bcl2l11,Tagln,Dusp1,Gadd45b,Eif2ak2,Mvp,Tnfaip3,Ier2,Prdm1,Atf3,Cxcl2,Oas2,Phlda1,Zfp36,Gem,Ppp1r15a,Csrp1,Tuba4a,Brd2,Txn1,Junb,Pgk1,Bambi,Cxcl1,Ier3,Ptgs2,Odc1,Trib1 |
| 4.987e-05 | -9.91 | regulation of endothelial cell apoptotic process | biological process | GO:2000351 | 54 | 13 | 20694 | 1406 |
Kdr,Cd40,Tnf,Icam1,Rgcc,Serpine1,Tnfaip3,Col18a1,Angpt1,Thbs1,Itga4,Ccl12,Il10 |
| 4.988e-05 | -9.91 | TCR signaling | REACTOME pathways | R-MMU-202403 | 108 | 23 | 8608 | 757 |
Nfkb1,Evl,Psme2b,Tab2,Nfkbia,H2-Ab1,Ptprj,Nck1,Psmb10,Ikbkg,Vasp,Ripk2,Psmb8,H2-Eb1,Psmd10,Malt1,H2-Aa,Psme2,Psma6,Psmb9,Psme1,Lcp2,Psmb6 |
| 4.992e-05 | -9.91 | small GTPase mediated signal transduction | biological process | GO:0007264 | 274 | 37 | 20694 | 1406 |
Rab9,Cdc42ep4,Cdc42ep2,Rab20,Plk2,Rapgef2,Rgl1,Dock10,Rras2,Rasgrp1,Rap2c,Rab21,Ralgds,G3bp2,Phactr4,Cyfip1,Rhou,Pdpn,Ksr1,Jun,Ift22,Bcl6,Rac3,Rhoh,Rhoc,Rnd1,Gpsm2,Rhof,Rhoq,Rapgef5,Rab19,Rab32,Dbnl,Hmox1,Dock4,Rnd3,Rab10 |
| 4.992e-05 | -9.91 | response to peptide hormone | biological process | GO:0043434 | 274 | 37 | 20694 | 1406 |
Irs2,Kat2b,Nfkb1,Cav1,Nr4a3,Rab10,Egr1,Igf1r,Socs7,Rhoq,Phip,Stat1,Stxbp3,Jak2,Ptk2,Trib3,Akt3,Il18,Sirt1,Ednrb,Ptpn2,Sesn3,Stat5a,Serpina3f,Serpina3g,Cacybp,Pde3b,Stat4,Cyfip1,Egr2,Stat2,Nr4a1,Slc9a1,Irf1,Stat3,Src,Agtrap |
| 4.999e-05 | -9.90 | GO_NEGATIVE_REGULATION_OF_B_CELL_ACTIVATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_B_CELL_ACTIVATION | 29 | 10 | 15632 | 1249 |
Casp3,Inhba,Tnfaip3,Atm,Prdm1,Fas,Il10,Samsn1,Bcl6,Lyn |
| 5.019e-05 | -9.90 | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN | 778 | 93 | 15632 | 1249 |
Ift57,Dusp4,Pla2g4a,Dnaja1,Gadd45b,Dhrs9,Sod2,Sqstm1,Srm,Ppp1r14b,Ifi207,Atp11b,Fbrsl1,Col4a2,Slc16a1,Lpcat2,Ubash3b,Ciapin1,Ifi214,Aldh1b1,Znrf3,Kctd12,Trim14,Ifi211,Mndal,S100a8,Tnfrsf1b,Mob3c,Fam162a,Fscn1,Rpgrip1l,Fam102b,Ifi204,Asb13,Dram1,Slc39a4,Cd302,Ifi209,Gnb4,Sla,Cutc,Slc25a12,Rrs1,Stip1,Pgk1,Kitl,Cdc42ep4,Gpr85,Naa25,Sdc2,Ikzf1,Myc,Tgs1,Rhof,Hivep2,Prdx1,Hivep3,Ifi203,Trip13,P2ry2,Dach1,Rnaset2b,Prkar2b,Tnfaip2,Adrb2,Fam111a,Dyrk2,Ccnd1,Mlkl,Tbc1d1,Ccdc86,Pnp2,Acpp,Rgs14,Ifi205,Slc2a1,Ehd1,Hsph1,Ifi213,Myo10,Mdfic,Ahsa1,Itga4,Ifi208,Rnaset2a,Fubp1,Sesn3,Dcbld2,Acsl5,Slamf8,Ak4,Slc43a3,Ldha |
| 5.024e-05 | -9.90 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 477 | 63 | 15632 | 1249 |
Nampt,Atp6v1d,Pdgfrb,Sipa1l1,Flrt2,Lcp2,Pdgfb,Caml,Ddit4,Nrp2,Tyk2,Hap1,Rapgef2,Ptprj,Arid5b,Plat,Pilrb1,Vegfc,Stat5a,Axl,Src,Rgs14,Rhoq,Casp3,Stat3,Csrnp1,Fgr,Hck,Mvp,Pdgfc,Crim1,Csf1,Met,Mmp9,Ptk2,Lyn,Adrb2,Kdr,Jak2,Arf4,Actb,Polr2g,Socs7,Igf1r,Itgav,Ccl12,Flrt3,Syk,Flt1,Ptpn2,Tiparp,Cyfip1,Stap1,Sdc2,Mapkapk2,Nck1,Irs2,Cdk5r1,Phip,Pilra,Pilrb2,Angpt1,Spred1 |
| 5.048e-05 | -9.89 | regulation of cellular senescence | biological process | GO:2000772 | 40 | 11 | 20694 | 1406 |
Pnpt1,Rbl1,Eef1e1,Arg2,Akt3,Nampt,Cgas,Hmga2,Bcl6,Plk2,Sirt1 |
| 5.053e-05 | -9.89 | receptor complex | cellular component | GO:0043235 | 391 | 48 | 20747 | 1409 |
Olr1,Cd40,Nr1h3,Tlr1,Ldlr,Pdgfrb,Tlr6,Notch1,Itga4,Lyn,Traf2,Itga5,Il13ra1,Ahr,Flt1,Il2rg,Syk,Lrp8,Calcrl,Axl,Itgav,Rnf31,Traf5,Cd74,Adrb2,Acvr1,Met,Rffl,Bmp2,Il4ra,Il18rap,Birc2,Csf3r,Igf1r,Acvr1b,Notch2,Acvrl1,Itgb8,Itga9,Ebi3,Il12rb1,Gpr84,Cd14,Itgal,Il6,Kctd12,Tlr2,Kdr |
| 5.056e-05 | -9.89 | regulation of protein catabolic process | biological process | GO:0042176 | 380 | 47 | 20694 | 1406 |
Rnf19a,Caml,Sco1,Ezr,Il10,Pml,Hspa1a,Ric1,Tnf,Plk3,Irak3,Gclc,Ptk2,Rnf19b,Cop1,Tmem67,Nupr1,Dnajb2,Hspa1b,N4bp1,Plk2,Tlk2,Ldlr,Ctsc,Odc1,Psme2,Usp25,Ankib1,Nos2,Rnf14,Psme1,Rnf139,Tnfrsf1b,Ier3,Arel1,Mdm2,Tiparp,Ppp2r3a,Il1b,Trib3,Samd9l,Timp1,Gja1,Psmd10,Trim30a,Trib1,Tnfaip3 |
| 5.079e-05 | -9.89 | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | 183 | 31 | 15632 | 1249 |
Pf4,Ldlr,Jak2,Cflar,Hmox1,Fndc3a,Casp7,Dram1,Uba7,Rap1gap2,Psme2,Atxn7l1,Casp8,Cd86,Tnfrsf1b,Rnf31,Hck,Fgr,Klf8,Ier2,Itga4,H2-Q7,Tapbp,Cers6,Nod2,Serp1,Tmem184b,Timp1,H2-Q6,Ifnar1,H2-Q4 |
| 5.079e-05 | -9.89 | GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_UP | MSigDB lists | GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_UP | 183 | 31 | 15632 | 1249 |
Aim2,Ier2,Irf2,Psmb10,P2ry14,Cdc42ep2,Tnfrsf14,Cd38,Cd40,Mgat1,Psmb9,Ly75,Mdn1,Tapbp,C1ra,Fgl2,Psmb6,Stat1,H2-Ab1,Il18,Gpd2,Il2rg,Prkx,Ikbke,Fscn1,Plcl2,Ccl5,S100a8,Arid4a,Psme2,H2-Aa |
| 5.079e-05 | -9.89 | GSE27786_CD4_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_CD4_TCELL_VS_NEUTROPHIL_UP | 183 | 31 | 15632 | 1249 |
Bcl2a1d,Slfn8,Dusp2,Ptpn2,Klf3,Bcl2a1b,Psip1,Rnf114,Rab3ip,Tap1,Spata13,Psmb10,Nxf1,Jmjd6,Tmem176b,Il12rb1,Cysltr2,Flnb,Rrs1,Jarid2,Fam162a,Pfkl,Ap3m2,Bcl2a1a,Whamm,Slfn9,Rgs1,Odc1,Phf6,Ifi35,Atp10a |
| 5.079e-05 | -9.89 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP | 183 | 31 | 15632 | 1249 |
Icam1,Kmo,Rtp4,Slco3a1,P2ry14,Nek6,Klf7,Hck,Slc28a2,Gnb4,Rbm43,Nfkbia,Gramd1a,Itgav,Ccnd1,Rsad2,Spry2,Prkce,Acvr1b,Ddx4,Map3k8,Il18,Ebi3,Ppfibp2,Plaur,Irf8,Gna15,Gem,Pdgfrb,Myadm,St3gal5 |
| 5.081e-05 | -9.89 | LEUZIPPRFOS | prints domains | PR00042 | 8 | 5 | 5821 | 374 |
Fosb,Jdp2,Fos,Atf3,Batf |
| 5.088e-05 | -9.89 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP | 158 | 28 | 15632 | 1249 |
Jun,Cited2,Dusp1,Parp8,Gadd45b,Plac8,Ogfrl1,Mpp7,Irs2,Ubash3b,Rnf139,Mxd1,Itga4,Zc3hav1,Samhd1,Tnfrsf8,Rap1gap2,Maff,St3gal5,Ext1,Ddit4,Isg20,Fam111a,Rcsd1,Kcna3,Ptgs2,Snn,Rgs1 |
| 5.088e-05 | -9.89 | GO_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM | MSigDB lists | GO_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM | 158 | 28 | 15632 | 1249 |
Ptafr,Adrb2,Adora2b,Ptgs2,Hmox1,Ptprj,Htr2b,Nos2,P2ry2,Cav1,Gja1,Gch1,Ednrb,Cx3cl1,Kat2b,Icam1,Hif1a,Abr,Angpt1,Cd38,Gclc,Htr2a,Dock4,Sod2,Plod3,Src,Gclm,Edn1 |
| 5.088e-05 | -9.89 | GSE27896_HDAC6_KO_VS_WT_TREG_UP | MSigDB lists | GSE27896_HDAC6_KO_VS_WT_TREG_UP | 158 | 28 | 15632 | 1249 |
Ccl4,Gfi1,Zhx2,Max,Zc3h12a,Parp3,Map3k8,Il12rb1,Mier3,Abtb2,Brd2,Dusp6,Psd4,Tshz1,Gem,Heatr6,Spred1,Spata13,Etv3,Kat2b,Socs1,Spry2,Ikzf1,Lrch1,Hivep2,Ppp6r1,Zswim4,Homer1 |
| 5.094e-05 | -9.88 | second-messenger-mediated signaling | biological process | GO:0019932 | 295 | 39 | 20694 | 1406 |
Ahr,Calcrl,Adgre4,Vcam1,Htr2b,Itpr1,Ccrl2,Edn1,Prkar2b,Sphk1,Ptgir,Ccr3,Rcan1,Ednrb,Adora2a,Mt2,Nos2,Tnf,Irgm2,Ksr1,P2ry12,Cacna1d,Cxcl10,Kdr,Ptger4,Ptprj,Xcr1,Ccr1,Cx3cr1,Fpr2,Adora2b,Adgrl2,Adgrg6,Prnp,Pf4,Adrb2,Slc9a1,Mt1,Rapgef2 |
| 5.113e-05 | -9.88 | nucleoside-triphosphatase activity | molecular function | GO:0017111 | 742 | 80 | 20217 | 1400 |
Gm5431,Igtp,Mcm9,Rnd3,Dhx58,Nkiras1,Tor3a,Tap2,Gm12185,Fignl2,Dync1h1,Gbp9,Hspa1a,Gbp2b,Rhof,Arl4a,Gbp8,Rab9,Tgtp1,Mov10,Tuba4a,Mx2,Rab20,Mcm6,Rnd1,Ifih1,Myo1b,Hspa2,Kif9,Rab10,Rhoc,Gng4,Gna15,Iigp1,Rras2,Gem,Mx1,Rhou,Kif3c,Rap2c,Ddx58,Rac3,Abcc5,Irgm1,Rab19,Gtpbp2,Kif5c,F830016B08Rik,Gch1,Hspa1b,Irgm2,Rhoq,Cenpe,Ascc3,Gbp7,Rab21,Gng12,Tgtp2,Ift22,Rhoh,Gbp3,Gm4951,9930111J21Rik1,Myo10,Rab32,Ifi47,Gnb4,Gm4841,Ep400,Atp13a1,Tap1,Katna1,Gbp2,Dync1i2,Chd9,Gng11,Abcb1a,Ddx4,Helz2,Abcc1 |
| 5.180e-05 | -9.87 | GO_NEGATIVE_REGULATION_OF_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TRANSPORT | 410 | 56 | 15632 | 1249 |
Mdfic,Notch1,Lif,Pml,Nfkbil1,Parp10,Cd74,Icam1,Rab11fip1,Rsad2,Nfkbie,Tnf,Rhbdf2,P2ry12,Thbs1,Keap1,Il1b,Hmox1,Zc3h12a,Ptger4,Ptgs2,Stxbp3,Fzd1,Inhba,G3bp2,Txn1,Osm,Htr2a,Pim3,Cd34,Angpt1,Abr,Nlrp3,Slc30a1,Nr1h3,Irs2,Cx3cl1,Il6,Prkce,Edn1,Itgav,Ezr,Crbn,Nfkbia,Psmd10,Pfkl,Mmp9,Dyrk2,Tlr9,Tnfsf4,Nfkbib,Nfkb1,Rabgef1,Cav1,Il10,Pid1 |
| 5.183e-05 | -9.87 | positive regulation of lipid metabolic process | biological process | GO:0045834 | 156 | 25 | 20694 | 1406 |
Fgr,Igf1r,Htr2b,Pcx,Lyn,Irs2,Nod2,Nr4a3,Prkce,Htr2a,Pdgfrb,Fabp3,Acsl5,Il1b,Nr1h3,Pdgfb,Flt1,Ptgs2,Tnf,Il1a,Src,Adora2b,Fpr2,Pla2g4a,Ldlr |
| 5.188e-05 | -9.87 | negative regulation of T cell differentiation | biological process | GO:0045581 | 47 | 12 | 20694 | 1406 |
Il4ra,Nfkbid,Ifnb1,Hlx,Socs1,Bcl6,Fgl2,Irf1,Zc3h12a,Ptpn2,Cd74,Tnfsf4 |
| 5.188e-05 | -9.87 | positive regulation of nitric oxide metabolic process | biological process | GO:1904407 | 47 | 12 | 20694 | 1406 |
Il1b,Ass1,Jak2,Tlr6,Il6,Klrk1,Klf2,Tnf,Ptgs2,Tlr2,Icam1,Sod2 |
| 5.260e-05 | -9.85 | regulation of mitotic cell cycle | biological process | GO:0007346 | 491 | 57 | 20694 | 1406 |
Rgcc,Edn1,Phip,Dync1h1,Ankrd17,Hspa2,Ube2e2,Rbl1,Trip13,Igf1r,Parp3,Pdgfrb,Myc,Plk3,Tnf,Pdpn,Il1a,Slfn1,Pnpt1,Stat5a,Cenpe,Hspa1a,Tpx2,Mecp2,Dcun1d3,Ccl12,Asah2,Cdkn1a,Pml,Met,Pbx1,Ccnd1,Ptch1,Sphk1,Il1b,Chmp4b,Pim3,Pttg1,Gpsm2,Ier3,Psme1,Sirt1,Mdm2,Btg2,Gpr132,Smc5,Tmod3,Psme2,Ccnd2,Atm,Pdgfb,Nek6,Ccne1,Casp2,Asns,Hspa1b,Plk2 |
| 5.276e-05 | -9.85 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_MULTIPOTENT_PROGENITOR_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_MULTIPOTENT_PROGENITOR_DN | 142 | 26 | 15632 | 1249 |
Vcan,Ythdf1,Insl6,Plod3,Ppp6r1,Rgs14,Arid5a,Ptpn2,Ankrd17,Fbrsl1,Mdfic,Mvp,Hck,Vcpip1,Kmo,Med13,Slc2a6,Ep400,Casp2,Ankib1,Sco1,Sik3,Pkp4,Dennd2a,Osgin2,Mcm6 |
| 5.276e-05 | -9.85 | RUIZ_TNC_TARGETS_UP | MSigDB lists | RUIZ_TNC_TARGETS_UP | 142 | 26 | 15632 | 1249 |
Bcl6,D16Ertd472e,Pde5a,Kdm5b,Ctsc,Sat1,Ifih1,Gbe1,Col18a1,Gbp2,Atp2b4,Extl2,Pdgfrb,C1rl,Plk2,Flrt2,Sema3c,Gdf15,Kctd12,Phlda1,Ddit4,Arid5b,St3gal1,Tnfsf10,Bambi,Vcam1 |
| 5.314e-05 | -9.84 | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP | 175 | 30 | 15632 | 1249 |
Smox,St3gal1,Ptgir,Acvr1b,Ptgs2,Sema4a,Thbs1,Ldlr,Ikbke,Frmd6,4930523C07Rik,Ppp1r15a,Zfp36,Ampd3,Trim56,Cdkn2d,Fbxo4,Klf7,Myo10,Mcmbp,Atp11b,Syk,Ass1,Arhgef3,Fos,Tcf4,Dock4,Cd40,Treml2,Mid1 |
| 5.314e-05 | -9.84 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN | 175 | 30 | 15632 | 1249 |
Gsr,Gpr35,Tank,Cd40,Dnaja1,Znfx1,Nlrc4,Hsph1,Pdgfc,Sdc4,Rnf34,Sav1,Kmo,Zfp513,Rars,Vasp,Zscan29,Ccrl2,Ttc9c,Birc3,Zhx2,Abcc1,Mob3c,Cd82,Tnip1,Cflar,Pdzd11,Il2rg,Lpar1,Ptprj |
| 5.314e-05 | -9.84 | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_UP | MSigDB lists | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_UP | 175 | 30 | 15632 | 1249 |
Rasgrp1,Btg2,Tlr1,Tnfsf14,Klf2,Ifit1bl2,Slc31a2,Card6,Tagap,Pkp4,Zhx2,Dnajb2,Ap3m2,Pilrb1,Mppe1,Ier3,Filip1l,Gpr68,Otud1,Ifit1bl1,Parp8,Hvcn1,Crim1,Slfn5,Pilrb2,Ccnd2,Ccl22,St3gal6,Traf1,Evl |
| 5.314e-05 | -9.84 | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN | MSigDB lists | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN | 175 | 30 | 15632 | 1249 |
Socs7,Dnajb2,Ikbke,Sema4a,Nr4a3,Pim2,Dyrk2,Rapgef2,Uba7,Inpp5b,Igsf8,Ptch1,Osm,Jarid2,Card6,Crim1,Rbms2,Ddx58,Tab2,Traf1,Slc30a1,Pgs1,Ddx60,Bcor,Fcgr2b,Mdn1,Prkce,Otud1,Parp8,Gsdmd |
| 5.415e-05 | -9.82 | SH2 | pfam domains | PF00017 | 97 | 19 | 18711 | 1348 |
Lcp2,Stat3,Nck1,Crkl,Stat1,Src,Stat4,Lyn,Fgr,Jak2,Syk,Socs7,Sla,Cish,Socs3,Socs1,Stat5a,Stat2,Hck |
| 5.432e-05 | -9.82 | response to hydrogen peroxide | biological process | GO:0042542 | 94 | 18 | 20694 | 1406 |
Hp,Lcn2,Axl,Kdm6b,Ppp1r15b,Bnip3,Pdgfrb,Nqo1,Sirt1,Src,Tnfaip3,Sod2,Hmox1,Nr4a3,Ripk3,Sphk1,Il6,Casp3 |
| 5.450e-05 | -9.82 | PID_FCER1_PATHWAY | MSigDB lists | PID_FCER1_PATHWAY | 60 | 15 | 15632 | 1249 |
Hcls1,Ptk2,Sphk1,Lyn,Map2k4,Pla2g4a,Fcgr2b,Dusp1,Syk,Nfkb1,Ikbkg,Lcp2,Fos,Jun,Map2k1 |
| 5.456e-05 | -9.82 | ZHANG_PROLIFERATING_VS_QUIESCENT | MSigDB lists | ZHANG_PROLIFERATING_VS_QUIESCENT | 47 | 13 | 15632 | 1249 |
Jun,Casp4,Itgav,Axl,Ccng2,Ccnd1,Mdm2,Casp3,Ccnd2,Itga5,Marcksl1,Plaur,Cxcl1 |
| 5.466e-05 | -9.81 | positive regulation of cellular protein catabolic process | biological process | GO:1903364 | 138 | 23 | 20694 | 1406 |
Gclc,Ptk2,Cop1,Rnf19b,Trib3,Rnf139,Mdm2,Psmd10,Nupr1,Dnajb2,Trib1,Tnfaip3,Tmem67,Ldlr,Ctsc,Ezr,Hspa1b,Rnf19a,Plk2,Ankib1,Plk3,Rnf14,Hspa1a |
| 5.499e-05 | -9.81 | Regulation of TNFR1 signaling | REACTOME pathways | R-MMU-5357905 | 27 | 10 | 8608 | 757 |
Traf2,Rnf31,Traf1,Tnfaip3,Birc2,Tax1bp1,Ikbkg,Casp8,Tnf,Birc3 |
| 5.517e-05 | -9.81 | GO_NEGATIVE_REGULATION_OF_MUSCLE_CONTRACTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MUSCLE_CONTRACTION | 19 | 8 | 15632 | 1249 |
Adora2b,Calcrl,Ptgs2,Adrb2,Dock4,Ptger4,Zc3h12a,Pde5a |
| 5.517e-05 | -9.81 | GO_REGULATION_OF_MACROPHAGE_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_MACROPHAGE_DIFFERENTIATION | 19 | 8 | 15632 | 1249 |
Csf1,Hcls1,Inhba,Pf4,Lif,Trib1,Ptpn2,Casp8 |
| 5.517e-05 | -9.81 | GO_CYTOPLASMIC_SEQUESTERING_OF_TRANSCRIPTION_FACTOR | MSigDB lists | GO_CYTOPLASMIC_SEQUESTERING_OF_TRANSCRIPTION_FACTOR | 19 | 8 | 15632 | 1249 |
Il10,Psmd10,Nfkbia,Nfkbil1,Nfkbie,G3bp2,Keap1,Nfkbib |
| 5.517e-05 | -9.81 | MARSON_FOXP3_CORE_DIRECT_TARGETS | MSigDB lists | MARSON_FOXP3_CORE_DIRECT_TARGETS | 19 | 8 | 15632 | 1249 |
Nfkbid,Jak2,Slfn3,Myc,Irf8,Slfn4,Gadd45b,Dusp6 |
| 5.527e-05 | -9.80 | GSE3982_MAC_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_MAC_VS_NEUTROPHIL_DN | 167 | 29 | 15632 | 1249 |
Gfi1,Trem1,Actb,Ptafr,Lyn,Pim2,Syne2,Nmi,Reps1,Isg20,C1rl,Tap2,Dach1,Junb,Arid4a,Tnfaip3,Apaf1,Sertad3,Nlrp3,Cdkn2d,Scarf1,Peli1,Dusp2,Birc2,Serp1,Abcc5,Ppp6r1,Cx3cr1,Parp8 |
| 5.527e-05 | -9.80 | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP | 167 | 29 | 15632 | 1249 |
Sesn3,Zc3h12c,Il18rap,Etv6,Tnip3,Arid5b,Orai2,Cldnd1,Ust,Slc7a11,Cst7,Sp140,Rhbdf2,Tank,Rbbp8,Irf4,Chst11,Prdm1,Fas,Tlr6,Lrp8,Nek6,Rnf135,Gpr141,Gbp3,Ripk3,Crim1,Atp2b4,Ncoa7 |
| 5.527e-05 | -9.80 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 167 | 29 | 15632 | 1249 |
Cd55,Lox,Adora2b,Ikbke,Plcl2,Ap3m2,Nfkb1,Pde4b,P2ry2,Asns,Lcp2,Tor1aip1,Csf3,Ier2,Il4ra,Kat2b,Crlf3,Klf7,Sqstm1,Tnf,Klf3,Serp1,Rhof,Cited2,Timp1,Arhgef3,Slc15a3,Ppp2r5a,Bnip3 |
| 5.552e-05 | -9.80 | transcription coregulator activity | molecular function | GO:0003712 | 450 | 54 | 20217 | 1400 |
Kmt5a,Rbbp8,Sap30,Tcf4,Pml,Zhx2,Hinfp,Ccnd1,Birc2,Ncoa7,Hmga1,Cdyl,Nupr1,Nr1h3,Tle3,Sirt1,Trib3,Bcl9,Spen,Helz2,Arid5b,Jdp2,Aebp2,Rbpms,Med21,Sqstm1,Daxx,Bcor,Nsd3,Kdm5b,Hdac1,Nmi,Med13,Riox2,Hspa1a,Kat2b,Dr1,Pou3f1,Cited2,Maml2,Parp9,Zfp281,Mtdh,Arid5a,Nr3c1,Rap2c,Cdyl2,Junb,Ifi204,Jun,Jmjd6,Cenpj,Mier3,Psip1 |
| 5.594e-05 | -9.79 | XU_AKT1_TARGETS_6HR | MSigDB lists | XU_AKT1_TARGETS_6HR | 24 | 9 | 15632 | 1249 |
Plscr1,Ifit3,Isg15,Ifih1,Ifit3b,Irf7,Oas3,Ifit1bl2,Ifit1bl1 |
| 5.594e-05 | -9.79 | GROSS_HIF1A_TARGETS_DN | MSigDB lists | GROSS_HIF1A_TARGETS_DN | 24 | 9 | 15632 | 1249 |
Bnip3,Prokr1,Pfkl,Fam162a,Pgk1,Tpi1,Gbe1,Jmjd6,Eno1 |
| 5.594e-05 | -9.79 | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | 24 | 9 | 15632 | 1249 |
Hcar2,Rapgef2,Sirt1,Nfkbid,Lyn,Nr4a3,Il10,Ccl5,Fas |
| 5.594e-05 | -9.79 | GO_DEVELOPMENTAL_PROGRAMMED_CELL_DEATH | MSigDB lists | GO_DEVELOPMENTAL_PROGRAMMED_CELL_DEATH | 24 | 9 | 15632 | 1249 |
Il1a,Fzd5,Bcl2l11,Notch1,Dnase1l3,Il1b,Casp2,Ppp2r1b,Kitl |
| 5.615e-05 | -9.79 | ribonucleoside binding | molecular function | GO:0032549 | 364 | 46 | 20217 | 1400 |
Iigp1,Rras2,Samhd1,Mx1,Gem,Rhoc,Rab10,Gna15,Gmppb,Irgq,Rhou,Rap2c,Tuba4a,Rab20,Arl5c,Rnd1,Gbp9,Tgtp1,Gbp2b,Rhof,Gbp8,Rab9,Arl4a,Nkiras1,Rnd3,Arl5b,Gbp2,Ift22,Mocs1,Rhoh,Gbp3,Cgas,Rab32,Hcar2,Rhoq,Rab21,Ehd1,Ciita,Gbp7,Ak4,Rac3,Irgm1,Arf4,Gch1,Rab19,Gtpbp2 |
| 5.619e-05 | -9.79 | GNF2_CD14 | MSigDB lists | GNF2_CD14 | 35 | 11 | 15632 | 1249 |
Fgl2,Nod2,Stx11,Cd302,Dusp1,Hk3,Hck,Tnfaip2,Cd14,Ms4a6d,Tlr2 |
| 5.619e-05 | -9.79 | GO_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT3_PROTEIN | MSigDB lists | GO_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT3_PROTEIN | 35 | 11 | 15632 | 1249 |
Jak2,Clcf1,Il15,Il18,Il12b,Ptger4,Lif,Socs3,Stat3,Il6,Osm |
| 5.651e-05 | -9.78 | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_UP | MSigDB lists | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_UP | 184 | 31 | 15632 | 1249 |
Dck,C3,Dram1,Egr3,Smox,Frmd4a,Odc1,Ikbke,Asf1a,Snapc1,Fam162a,Arid4a,Lap3,Cacybp,Slc2a6,Zeb1,Ddit4,Bcor,Prnp,Cd83,Relb,Cst7,Srm,Stat5a,Nfkbia,Tspan3,Tor1aip2,Mdn1,Phlpp1,S1pr2,Ap3b1 |
| 5.651e-05 | -9.78 | GSE24210_RESTING_TREG_VS_TCONV_UP | MSigDB lists | GSE24210_RESTING_TREG_VS_TCONV_UP | 184 | 31 | 15632 | 1249 |
Notch2,Tmem123,Azi2,Lyn,Cpeb4,Mtmr14,Traf3ip2,Syne2,Rasgrp1,Zeb1,Atxn7l1,Cnp,Klf2,Itgal,Plekha2,Cep350,4930523C07Rik,Myadm,Cd164,Sla,Rbm43,Papss2,Arrdc4,Hhex,Rhoh,Arhgap26,Ap3b1,Arid5a,Itpr1,Rgs14,Klf3 |
| 5.651e-05 | -9.78 | GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN | 184 | 31 | 15632 | 1249 |
Snx10,Ankib1,Cnp,Rnaset2a,Vps54,Gbp7,Usp12,Il18rap,Dgka,Kctd12,Atp10a,Tmod3,Rcn1,Inpp1,Rnaset2b,Wdr43,Dbnl,Phlpp1,Nfkbie,Ift57,Irf2,Egr1,Calcrl,Tab2,Rab19,Sell,Sla,Ube2f,Cd164,Irak3,Samhd1 |
| 5.702e-05 | -9.77 | GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_UP | MSigDB lists | GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_UP | 111 | 22 | 15632 | 1249 |
Dr1,Slc29a3,Fcho2,Piezo1,Zfp36,Slamf9,Casp2,Mthfd1l,Lnpep,Gch1,Vezt,Pid1,Tmc3,Cd38,Irak3,Samhd1,Rbl1,Tap1,Malt1,Stat3,Cdyl2,Ankrd17 |
| 5.705e-05 | -9.77 | REACTOME_SIGNALING_BY_SCF_KIT | MSigDB lists | REACTOME_SIGNALING_BY_SCF_KIT | 74 | 17 | 15632 | 1249 |
Trib3,Socs1,Lyn,Stat1,Mmp9,Cdkn1a,Jak2,Kitl,Map2k1,Nr4a1,Stat5a,Src,Rictor,Mdm2,Phlpp1,Stat3,Akt3 |
| 5.705e-05 | -9.77 | PID_CD8_TCR_DOWNSTREAM_PATHWAY | MSigDB lists | PID_CD8_TCR_DOWNSTREAM_PATHWAY | 74 | 17 | 15632 | 1249 |
Ifnar1,H2-Q4,Tnf,Junb,Jun,Map2k1,Fos,H2-Q6,Ifna6,Prkce,Ifna5,Stat4,Egr1,H2-Q7,Il2rg,Ifna1,Ifna2 |
| 5.718e-05 | -9.77 | negative regulation of endopeptidase activity | biological process | GO:0010951 | 205 | 30 | 20694 | 1406 |
Thbs1,Hspa1b,Src,Birc3,Plaur,Nr4a1,Slpi,Il6,Rnf34,Bcl2a1d,Cflar,Rffl,Adora2a,Serpinb6b,Serpina3g,Serpina3f,Ptgs2,Mdm2,Mmp9,C3,Cst7,Serpinb9b,Birc2,Serpinb2,Prdx5,Timp1,Cdkn2d,Serpine1,Tnfsf14,Serpinb9 |
| 5.768e-05 | -9.76 | IL-2 Signaling Pathway | WikiPathways | WP450 | 76 | 21 | 4813 | 540 |
Lyn,Nr3c1,Cish,Nmi,Pik3cd,Stat1,Stat5a,Map2k1,Ifna1,Syk,Icam1,Stat3,Crkl,Nfkb1,Ets2,Irs2,Jak2,Mapkapk2,Il2rg,Socs1,Socs3 |
| 5.869e-05 | -9.74 | GO_NEGATIVE_REGULATION_OF_PROTEIN_SECRETION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_SECRETION | 96 | 20 | 15632 | 1249 |
Pfkl,Il1b,Angpt1,Cd34,Pim3,Nr1h3,Nlrp3,Cx3cl1,Ptger4,Tnfsf4,Zc3h12a,Pml,Rsad2,Rab11fip1,Il6,Il10,Rhbdf2,Rabgef1,Ezr,Tnf |
| 5.893e-05 | -9.74 | KRAS.LUNG.BREAST_UP.V1_UP | MSigDB lists | KRAS.LUNG.BREAST_UP.V1_UP | 119 | 23 | 15632 | 1249 |
Prdm1,Lif,St3gal6,Traf1,Tnfaip3,Dhrs9,Gypc,Dock4,Spry2,Mmp9,Kif5c,Ptgs2,Cmklr1,Cxcl1,Adam19,Glrx,Gfi1,Birc3,Isg20,Tnfsf15,Csf3,Inhba,Cxcl2 |
| 5.893e-05 | -9.74 | response to ischemia | biological process | GO:0002931 | 34 | 10 | 20694 | 1406 |
Rcan1,Uchl1,Cx3cr1,Cav1,Hk1,Cx3cl1,Csf1,Egr1,Hk2,Cpeb4 |
| 5.898e-05 | -9.74 | Small_GTPase_Rho | interpro domains | IPR003578 | 21 | 8 | 19984 | 1430 |
Rhof,Rhoc,Rnd1,Rhou,Rhoq,Rac3,Rhoh,Rnd3 |
| 5.918e-05 | -9.73 | STANHILL_HRAS_TRANSFROMATION_UP | MSigDB lists | STANHILL_HRAS_TRANSFROMATION_UP | 7 | 5 | 15632 | 1249 |
Fos,Jun,Hspa1a,Dusp1,Hmox1 |
| 5.918e-05 | -9.73 | BAKER_HEMATOPOESIS_STAT5_TARGETS | MSigDB lists | BAKER_HEMATOPOESIS_STAT5_TARGETS | 7 | 5 | 15632 | 1249 |
Pim1,Ccnd2,Ccnd1,Myc,Ccne1 |
| 5.926e-05 | -9.73 | GSE3982_BCELL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_BCELL_VS_BASOPHIL_DN | 176 | 30 | 15632 | 1249 |
Hp,Sema4c,Dram1,Osgin2,Itga9,Osbpl3,Ptges,Fcgr4,S100a8,Jarid2,Sema3c,C1rl,Rims3,Pstpip2,Bst1,Palld,Pilra,Pdgfc,Crim1,Atp2b4,Cx3cr1,Klf3,Dusp1,Abcc5,Cst7,D16Ertd472e,Ets2,Ppp2r5a,Acvr1,Chst11 |
| 5.926e-05 | -9.73 | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP | 176 | 30 | 15632 | 1249 |
Ifi204,Phf11d,Tnfrsf1b,Pdk3,Mndal,Ifi208,Gpr132,Ifi211,Isg20,Ifi203,Bcor,Irf2,Pgs1,Ifi214,Dcp2,Phf11a,Phf11c,Notch1,Ifi207,Ifi213,Phf11b,Gpsm2,Ifi205,Ifi209,Casz1,Dusp2,1110038F14Rik,Ikzf1,Chst11,Hdac1 |
| 5.926e-05 | -9.73 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_UP | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_UP | 176 | 30 | 15632 | 1249 |
Plekha5,Axl,Dse,Gbp9,Ppp2r5a,Gbp4,Acvrl1,Gpr68,Chst11,Errfi1,Mxd1,St3gal6,Pgm1,1600014C10Rik,Rab3ip,Ifit1,Ahrr,Abtb2,Gna15,Hopx,Itgal,Flnb,Rnf19a,Herc6,Tnip1,Ccl4,Lrp11,Znrf1,Frmd6,Igf1r |
| 5.992e-05 | -9.72 | GO_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | 219 | 35 | 15632 | 1249 |
Birc3,Casp8,Serpine1,Mndal,Tnfsf14,Slpi,Ifi208,Ifi211,Ifi203,Spint2,C3,Mmp9,Serpinb9,Ifi204,Thbs1,Serpinb2,Plaur,Cst7,Ifi213,Src,Ifi205,Ifi209,Birc2,Nlrc4,Timp1,Il6,Rffl,Prdx5,Mdm2,Cdkn2d,Ifi214,Pttg1,Rnf34,Crim1,Ifi207 |
| 5.993e-05 | -9.72 | GSE43863_NAIVE_VS_LY6C_LOW_CXCR5NEG_CD4_EFF_TCELL_D6_LCMV_UP | MSigDB lists | GSE43863_NAIVE_VS_LY6C_LOW_CXCR5NEG_CD4_EFF_TCELL_D6_LCMV_UP | 127 | 24 | 15632 | 1249 |
Jdp2,AA467197,Tmem176a,Fabp7,Icosl,Vcam1,Cxcl1,Bcl2a1a,Ccl4,Col27a1,Nfkb2,Tnfaip2,Mgat1,Bcl2a1b,Ccl12,Optn,Sele,Nod2,Nfkbie,Bcl2a1d,Rffl,Gbp4,Gbp9,Atf3 |
| 6.004e-05 | -9.72 | purine nucleoside binding | molecular function | GO:0001883 | 365 | 46 | 20217 | 1400 |
Rab32,Cgas,Rhoh,Gbp3,Ift22,Mocs1,Gbp2,Arl5b,Gtpbp2,Rab19,Gch1,Arf4,Irgm1,Rac3,Ak4,Gbp7,Ciita,Ehd1,Rab21,Rhoq,Hcar2,Rab20,Rnd1,Arl5c,Tuba4a,Rhou,Rap2c,Irgq,Gmppb,Gna15,Rhoc,Rab10,Samhd1,Gem,Mx1,Iigp1,Rras2,Rnd3,Nkiras1,Gbp8,Arl4a,Rab9,Gbp2b,Rhof,Tgtp1,Gbp9 |
| 6.015e-05 | -9.72 | regulation of type I interferon-mediated signaling pathway | biological process | GO:0060338 | 22 | 8 | 20694 | 1406 |
Zbp1,Nlrc5,Ptpn2,Mul1,Irf7,Ikbke,Samhd1,Adar |
| 6.015e-05 | -9.72 | negative regulation of growth of symbiont involved in interaction with host | biological process | GO:0044146 | 22 | 8 | 20694 | 1406 |
Il12b,Tnf,Tlr2,Il10,Irf8,Nod2,Myd88,Sqstm1 |
| 6.015e-05 | -9.72 | negative regulation of interleukin-1 beta production | biological process | GO:0032691 | 22 | 8 | 20694 | 1406 |
Tnfaip3,Cx3cr1,Pml,Nlrp3,Mefv,Zc3h12a,Errfi1,Acp5 |
| 6.084e-05 | -9.71 | mitochondrial outer membrane | cellular component | GO:0005741 | 167 | 26 | 20747 | 1409 |
Hk2,Rmdn3,Bcl2a1a,Tomm70a,Hk1,Snn,Bnip3,Rsad2,Slc44a1,Rab32,Kmo,Gk,Mul1,Gja1,Acsl1,Ass1,Trim14,Tspo,Prnp,Cnp,Agpat4,Bcl2a1d,Armcx6,Bcl2a1b,Ppp1r15a,Acsl5 |
| 6.181e-05 | -9.69 | GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_UP | MSigDB lists | GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_UP | 168 | 29 | 15632 | 1249 |
Stat4,Csf3,Jag1,Inhba,Lcp2,Rnf31,Gch1,Ccl5,Htr2b,Il1b,Cxcl1,Clic4,Slc43a3,Ptgs2,Il12b,Map3k8,Dram1,Abcb1a,Gclm,Il6,Itpr1,Gadd45b,Tnf,Cst7,Rhoc,Slamf7,Icam1,Plk3,Hlx |
| 6.181e-05 | -9.69 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_NKCELL_DN | 168 | 29 | 15632 | 1249 |
Dpy19l1,Plac8,Rhbdf2,Cd302,Psmd10,Tspan3,Rab11fip1,Rhoq,Ctsc,Cebpd,Phactr4,Cox17,Arhgap26,Palld,Tpi1,Nfkbil1,Cd38,Rgs3,Enpp4,Rnf14,Ccl5,Plek,Irf8,Pde7b,Dram1,Lyn,Ldlr,Gfi1,Nfil3 |
| 6.181e-05 | -9.69 | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_DN | 168 | 29 | 15632 | 1249 |
Bcl2a1a,Gfi1,Stip1,Mob3c,Cd200,Egr3,Nr4a3,Slc39a14,Gem,Rrs1,Irf8,Tnfsf14,Asns,Rnf34,Prdx1,Prpf38a,Cish,Pnp2,Egr2,Ccdc86,Irf4,Bcl2a1d,S1pr2,Srm,Ppp1r14b,Ifnar1,Bcl2a1b,Tnf,Dse |
| 6.238e-05 | -9.68 | MODULE_399 | MSigDB lists | MODULE_399 | 54 | 14 | 15632 | 1249 |
Ahr,Il1b,Tnfaip3,Cd38,Cd14,Il18,Traf1,Stat1,Cd40,Tnfrsf1b,Dusp6,Casp1,Nfkbia,Eif2ak2 |
| 6.238e-05 | -9.68 | MORI_LARGE_PRE_BII_LYMPHOCYTE_DN | MSigDB lists | MORI_LARGE_PRE_BII_LYMPHOCYTE_DN | 54 | 14 | 15632 | 1249 |
Cd74,Il2rg,Il4ra,Samhd1,Cd83,Vcam1,Rgs14,Irf8,Cd40,Birc3,Itgav,Tapbp,Uba7,H2-Aa |
| 6.238e-05 | -9.68 | GNF2_PECAM1 | MSigDB lists | GNF2_PECAM1 | 54 | 14 | 15632 | 1249 |
Nod2,Fgl2,Cebpd,Zfp36,Igsf6,Cd302,Ccr1,Dusp1,Tnfrsf1b,Casp1,Hck,Tnfaip2,Ms4a6d,Tlr2 |
| 6.271e-05 | -9.68 | transport | biological process | GO:0006810 | 3343 | 280 | 20694 | 1406 |
Vps54,Myc,Htr2a,Rab3ip,Rnf19b,Ptk2,Slc25a22,Rac3,Nr1h3,Antxr1,Hspa2,Stx6,Rhoq,Slc48a1,Dennd1b,Fcgr1,Slc9a1,Stard5,Adrb2,Arrdc4,Nfkbia,Slc30a1,Ppfia3,Dio2,D1Ertd622e,Ezr,Calhm6,Scyl2,Mecp2,Kif5c,Stat5a,Pdpn,Ap3b1,Rhou,Pnpt1,Optn,Orai2,Pou2f2,Abcc4,Apba1,Gramd1a,Rgs14,Ranbp2,Nlrp3,Rin2,Slco3a1,Rab19,Lrp11,Tlr6,Lcp2,Nlrc4,Inhba,Adar,Treml4,Nxf1,Tmc3,Aftph,Hck,Stat3,Bcl2l11,Src,Lcn2,Kcnj2,Fpr2,Snx10,Sec24a,Map2k1,4932438A13Rik,Ly75,Dst,Ero1l,Slc25a25,Ptafr,Kcna3,Arl4a,Piezo1,Bnip3,Ednrb,Slc4a7,Cd14,Ccdc88b,Traf3ip2,Il1rn,Slc28a2,Clic4,Stxbp3,Slc37a3,Notch2,Calcrl,Slc7a5,Rab10,Chic2,Fnbp1l,Ift57,Rtn2,Stra6l,Myd88,Serp1,Met,Cdkn1a,Mfsd7a,Pikfyve,Pla2g4a,Cp,Abcc1,Fcgr2b,Egr2,Rffl,P2ry12,Cacna1d,Magohb,Atp6v1d,Slc16a3,Slc7a2,Lrrc8c,Mppe1,Mapkapk2,Pmaip1,Isg15,Slc39a14,Slc30a4,Hk2,Gja1,Itgav,Rtp4,Slc15a3,Ccnd1,Nr4a3,Clcn5,Thbs1,Grk3,Cacnb3,Plek,Trem1,Rrbp1,Ap3m2,Il6,G3bp2,Hif1a,Atp11b,Svbp,Slc12a9,Dtx3l,Itga4,Zfp36,Clic5,Stau1,Dnaja1,Edn1,Hvcn1,Carmil1,Nod2,Lrp8,Rubcnl,Tap2,Clcn7,Rab21,Cnp,Xkr8,Mcoln2,Abcb1a,Atp2b4,Hspa1a,Kif3c,Tspo,Rab11fip1,Fchsd2,Ehd1,Aim2,Tomm70a,Itgal,Trip10,Plekhf2,Scarf1,Cd302,Chmp4b,Notch1,Slc31a1,Marcksl1,Marco,Fam53c,Tlr2,Myo1b,Micall2,Hap1,Casp1,Xcr1,Ldlr,Rrs1,Stx11,Nfkbie,Scn1b,Slc29a3,Atp10a,Rilpl1,Cyth3,Lrp4,Mul1,Rhbdf2,Nos2,Lipg,Sec24b,Tbc1d1,Ift22,Slc25a12,Actb,Malt1,Fabp3,Cd74,Tnfaip2,Nlgn2,Atp13a1,Igf2bp2,Phip,Dennd2a,Msr1,Dync1h1,Arl5b,Uchl1,Slc16a1,Jmjd6,Ccl5,Rabgef1,Milr1,Arl5c,Slc13a3,Rab20,Pml,Ccr1,Slc44a1,Rasgrp1,Sh3bp4,Ric1,Syk,Osbpl3,Stxbp1,Fcho2,Snx2,Arf4,Ier3,Slc2a1,Acsl5,Axl,Irf8,Tap1,Cd274,Hhex,Dbnl,Tbc1d13,Rab32,Samd9l,Itpr1,Slc39a4,Htr2b,Rims3,Pdzd11,F11r,Atp11a,Cav1,Lyn,Slc7a11,Abcc5,Parp11,Spire1,Slc7a8,Slc31a2,Slc39a13,Whamm,Slc43a3,Rab9,Plscr1,Stoml1,Slc25a37,Kpna3,Acsl1,Syne2,Reps1,Cox18,Anp32a,Stard7 |
| 6.280e-05 | -9.68 | GO_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | 104 | 21 | 15632 | 1249 |
Kitl,Hcls1,Pf4,Tlr3,Lif,Ubash3b,Trib1,Lyn,Il12b,Csf1,Myc,Inhba,Gpr68,Tnf,Ccr1,Ccl5,Fos,Ptpn2,Irf7,Jun,Casp8 |
| 6.280e-05 | -9.68 | GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP | 185 | 31 | 15632 | 1249 |
Cd164,Prpf4,Tap1,Crlf3,Arg2,Rtp4,Nxf1,Znrf3,Nfkbie,Treml2,Parp9,Gpr84,Gramd1a,Ifit1bl1,Trim36,Ddhd1,Zhx2,Vrk2,Cd82,Mppe1,Asb13,Egr3,Syne2,Kctd12,Gpr132,Vezt,Ifit1bl2,4933430I17Rik,Jarid2,4930523C07Rik,Rnf31 |
| 6.280e-05 | -9.68 | GSE360_DC_VS_MAC_L_DONOVANI_DN | MSigDB lists | GSE360_DC_VS_MAC_L_DONOVANI_DN | 185 | 31 | 15632 | 1249 |
Sele,Ifi44,Csf3r,Acpp,Timp1,Ccl12,Ifit1bl1,Dusp14,Mdfic,Zc3hav1,Gclc,Pde3b,Cd14,Myd88,Rnd3,St3gal6,Dmxl2,Atf3,Usp12,Gem,Fubp1,Itgal,P4ha1,Ccr1,Ifit1bl2,Eno2,Glrx,Socs7,Nsmaf,Ldha,Cd55 |
| 6.280e-05 | -9.68 | GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_DN | MSigDB lists | GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_DN | 185 | 31 | 15632 | 1249 |
Dtx2,Ms4a6d,Znrf1,Tnip1,Pkp4,Jarid2,Ccl5,Irf7,Uba7,Dgka,Fas,Evl,Slco3a1,Ifih1,Isg15,Traf1,Agtrap,Sell,Gnb4,Slc25a25,Ifit1,Mark2,Notch1,Klf7,Tap1,Nr4a1,Agrn,Cst7,Zyx,Dusp2,Atp13a1 |
| 6.283e-05 | -9.68 | LEE_AGING_CEREBELLUM_UP | MSigDB lists | LEE_AGING_CEREBELLUM_UP | 89 | 19 | 15632 | 1249 |
Gbp3,H2-Ab1,Hmox1,Notch1,Dnajb2,Bcl2a1a,Gng11,Gna15,Fos,Irf7,Nr4a1,Axl,Ifit1bl1,Ifit1bl2,Cst7,Bcl2a1b,Bcl2a1d,Tbc1d1,Irgm2 |
| 6.295e-05 | -9.67 | regulation of T-helper 1 cell differentiation | biological process | GO:0045625 | 12 | 6 | 20694 | 1406 |
Hlx,Ripk2,Il4ra,Tnfsf4,Il27,Irf1 |
| 6.295e-05 | -9.67 | positive regulation of natural killer cell differentiation | biological process | GO:0032825 | 12 | 6 | 20694 | 1406 |
Il15ra,Axl,Stat5a,Rasgrp1,Irf1,Il15 |
| 6.365e-05 | -9.66 | regulation of interferon-alpha production | biological process | GO:0032647 | 28 | 9 | 20694 | 1406 |
Irf7,Zc3hav1,Nmi,Ddx58,Gbp4,Ifih1,Tlr9,Tlr3,Stat1 |
| 6.391e-05 | -9.66 | G_GB1_RHD3 | prosite domains | PS51715 | 15 | 7 | 13278 | 1037 |
Gbp2b,Gbp3,Gbp4,Gbp9,Gbp7,Gbp2,Gbp8 |
| 6.408e-05 | -9.66 | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP | 160 | 28 | 15632 | 1249 |
Cd69,Rap1gap2,Btg2,St3gal5,Klf2,Pde4b,Plek,Junb,Map4k4,Snn,Whamm,Chd9,Ptgs2,Kcna3,Pim1,St7,Ptprj,Tnfsf8,Fos,Otud1,Cited2,Parp8,Dusp1,Etv3,Irs2,Sell,Nfkbiz,Rnf139 |
| 6.417e-05 | -9.65 | GO_RESPONSE_TO_ESTROGEN | MSigDB lists | GO_RESPONSE_TO_ESTROGEN | 211 | 34 | 15632 | 1249 |
Pdgfb,Mmp13,Ccne1,Ccl5,Il10,Cav1,Ptch1,Casp8,Pdgfrb,Il1b,C3,Ldha,Socs3,Hmox1,Ptgs2,Adrb2,Serpinb9,Stat3,Casp3,Mmp14,Ccnd1,Mecp2,Mdm2,Nqo1,Dusp1,Ass1,Rbbp8,Cited2,Cd38,Ahr,Fas,Hif1a,Socs1,Il4ra |
| 6.478e-05 | -9.64 | regulation of cell adhesion mediated by integrin | biological process | GO:0033628 | 41 | 11 | 20694 | 1406 |
Crkl,Syk,Piezo1,Ccl5,Serpine1,Lyn,P2ry12,Plau,Swap70,Rac3,Ptk2 |
| 6.478e-05 | -9.64 | leukocyte mediated cytotoxicity | biological process | GO:0001909 | 41 | 11 | 20694 | 1406 |
Il18,Trem1,Fcgr1,Raet1e,Prdx1,Serpinb9b,Ctsc,Serpinb9,Stx11,Rnf19b,H60b |
| 6.493e-05 | -9.64 | antigen processing and presentation of peptide antigen via MHC class I | biological process | GO:0002474 | 48 | 12 | 20694 | 1406 |
Tap2,H2-Q7,H2-Q4,Tap1,Tapbp,Tapbpl,H2-Q6,H2-T22,H2-T10,H2-M2,H2-T24,Fcgr1 |
| 6.493e-05 | -9.64 | regulation of acute inflammatory response | biological process | GO:0002673 | 48 | 12 | 20694 | 1406 |
Il1b,Nlrp3,Fcgr2b,C3,Ednrb,Fcgr1,Spn,Dnase1l3,Tnf,Ptgs2,Ccl5,Il6 |
| 6.560e-05 | -9.63 | guanyl ribonucleotide binding | molecular function | GO:0032561 | 377 | 47 | 20217 | 1400 |
Rab20,Rnd1,Arl5c,Tuba4a,Irgq,Rhou,Rap2c,Gmppb,Rhoc,Rab10,Gna15,Iigp1,Rras2,Samhd1,Mx1,Gem,Rnd3,Nkiras1,Gbp2b,Rhof,Arl4a,Gbp8,Rab9,Tgtp1,Gbp9,Pde5a,Cgas,Rab32,Mocs1,Ift22,Rhoh,Gbp3,Gbp2,Arl5b,Rab19,Gtpbp2,Arf4,Gch1,Rac3,Irgm1,Ak4,Ciita,Gbp7,Rab21,Ehd1,Rhoq,Hcar2 |
| 6.560e-05 | -9.63 | guanyl nucleotide binding | molecular function | GO:0019001 | 377 | 47 | 20217 | 1400 |
Arl5b,Gbp2,Ift22,Mocs1,Gbp3,Rhoh,Cgas,Rab32,Hcar2,Rhoq,Rab21,Ehd1,Ciita,Gbp7,Ak4,Rac3,Irgm1,Arf4,Gch1,Rab19,Gtpbp2,Rras2,Iigp1,Gem,Mx1,Samhd1,Rab10,Rhoc,Gna15,Gmppb,Irgq,Rap2c,Rhou,Tuba4a,Rnd1,Arl5c,Rab20,Gbp9,Pde5a,Tgtp1,Rhof,Gbp2b,Gbp8,Arl4a,Rab9,Nkiras1,Rnd3 |
| 6.570e-05 | -9.63 | Downstream signal transduction | REACTOME pathways | R-MMU-186763 | 301 | 47 | 8608 | 757 |
Psme1,Prkar2b,Dusp5,Psmb6,Dusp6,Rapgef2,Stat1,Pde1b,Rasgrp1,Psme2,Psma6,Cd80,Trib3,Mdm2,Stat3,Met,Ptk2,Ier3,Psmb8,Cd86,Jak2,Map2k1,Ksr1,Il2rg,Pdgfrb,Rictor,Ppp2r5a,Irs2,Kitl,Cdkn1a,Pdgfb,Crkl,Pik3cd,Stat5a,Psmb9,Psmd10,Phlpp1,Nck1,Psmb10,Ppp2r1b,Nr4a1,Prkce,Angpt1,Psme2b,Src,Phlpp2,Spred1 |
| 6.589e-05 | -9.63 | GSE360_L_DONOVANI_VS_L_MAJOR_DC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_L_MAJOR_DC_DN | 194 | 32 | 15632 | 1249 |
Rtn2,Zfp36,Slc25a12,Usp12,S100a8,Casp4,Il10,Asf1a,Ralgds,Bcl2a1a,Socs7,Rnf19b,Nr4a3,Grina,Trib1,Cers6,Bcl2a1d,Gadd45g,Bcl2a1b,Dusp1,Klf6,H2-Q4,Dock4,Eno1,H2-Q6,Gpc1,Hinfp,Crim1,Mthfr,H2-Q7,Atf3,Hlx |
| 6.598e-05 | -9.63 | GO_RESPONSE_TO_PURINE_CONTAINING_COMPOUND | MSigDB lists | GO_RESPONSE_TO_PURINE_CONTAINING_COMPOUND | 152 | 27 | 15632 | 1249 |
Ccne1,Junb,P2ry2,Fosb,Ppp1r15a,Rapgef2,Ldha,Stat1,Hmgcs1,Ptafr,Ptgs2,Il1b,Ass1,Ccl12,Casp1,Ezr,Dusp1,Birc2,Jun,Fos,P2ry12,Il6,Sdc2,Sphk1,Sell,Hif1a,Sdc1 |
| 6.598e-05 | -9.63 | GSE32901_NAIVE_VS_TH1_CD4_TCELL_DN | MSigDB lists | GSE32901_NAIVE_VS_TH1_CD4_TCELL_DN | 152 | 27 | 15632 | 1249 |
Pik3r6,Plk2,Irf8,Samsn1,Plek,Slamf9,Lyn,Sema4c,Rcl1,Ccl4,Swap70,Tnf,Nr4a1,Phactr4,Egr2,Fchsd2,Myc,Cish,Fcgr2b,Cd74,Cd180,Mcm10,Nfkbiz,Cd38,Cd80,Slamf7,Cd83 |
| 6.601e-05 | -9.63 | GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_DN | MSigDB lists | GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_DN | 177 | 30 | 15632 | 1249 |
G3bp2,Tyk2,Parp12,Pid1,Gna15,Asns,Plekha2,Tor3a,Fam162a,Cldnd1,Inpp1,Trib1,Rac3,Chst11,B3gnt5,Psma6,Acvrl1,Dennd1b,Ubtd2,Ifi44,Dpy19l1,Cd38,Il15,Pbx1,Rab19,Coa5,Ubash3b,Sell,Pgs1,Evl |
| 6.601e-05 | -9.63 | GSE3982_EOSINOPHIL_VS_NKCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_NKCELL_DN | 177 | 30 | 15632 | 1249 |
Minpp1,Gclm,Ifi209,Ankrd17,Ifi205,Tspan3,Cyfip1,Plac8,Ifi213,Aoah,Ifi207,Ifi214,Palld,Rnf139,Psme1,Ifi203,Stat4,Ccdc25,Ifi208,Trim14,Ifi211,Caml,Ksr1,Mndal,Prkx,Osbpl3,Ifi204,Phyh,Sema4c,Endod1 |
| 6.601e-05 | -9.63 | GSE14308_TH17_VS_NATURAL_TREG_DN | MSigDB lists | GSE14308_TH17_VS_NATURAL_TREG_DN | 177 | 30 | 15632 | 1249 |
Ppp2r2a,Cmpk2,Chd9,Ppp2r1b,Elmod2,Clcn7,Cxcl10,Trib1,Rcan1,Il13ra1,Rap1gap2,Tdrd7,Sirt1,Wars,Tlr1,Relb,Ifih1,Slc30a1,Ppm1l,Stat2,Kat2b,Ppp2r5a,Phgdh,Traf2,Pik3r5,N4bp1,Nfkbia,Spsb1,Morc3,Tnf |
| 6.603e-05 | -9.63 | ENK_UV_RESPONSE_KERATINOCYTE_UP | MSigDB lists | ENK_UV_RESPONSE_KERATINOCYTE_UP | 501 | 65 | 15632 | 1249 |
C1ra,Dusp8,Pnp2,Rab9,Rnf24,Itpr1,H2-Q6,Eno1,Dusp1,Casp1,Txnrd1,Tnfaip3,Isg15,Psme1,Mxd1,H2-Q7,Ier2,Vasp,Cxcl2,Maff,Stx11,Ppp1r15a,Lad1,Asns,Junb,Brd2,Csrp1,Il1b,Ppp2r2a,Cxcl1,Snapc1,Bambi,St7,Dusp5,Ifrd1,Dtnb,Spry2,Mmp14,Fos,Jun,Ets2,Cited2,Hmga1,Dnaja1,Gadd45b,H2-Q4,Tagln,Dusp14,Rnd3,Sdc4,Nxf1,Cx3cl1,Atf3,Isg20,Zfp36,Alas1,Gem,Psmb8,Tnfrsf1b,Cdkn1a,Dnajb2,Trib1,Odc1,Ier3,Ell2 |
| 6.642e-05 | -9.62 | regulation of body fluid levels | biological process | GO:0050878 | 341 | 43 | 20694 | 1406 |
Axl,Procr,Prkce,Ccnd1,Slc7a11,Cav1,Lyn,Gja1,Ptprj,F10,Plek,Cd34,Thbs1,Hif1a,Pdgfb,Nr1h3,Enpp4,C3,Ednrb,Oas2,Papss2,Serpine1,Edn1,Stxbp3,Mllt6,Plau,Met,Pf4,Adrb2,Evl,P2ry2,Adora2a,Cx3cl1,Pdpn,Ap3b1,Stat5a,P2ry12,Stxbp1,Mmp13,Lnpk,Syk,Ubash3b,Ptger4 |
| 6.647e-05 | -9.62 | Znf_RING | interpro domains | IPR001841 | 274 | 38 | 19984 | 1430 |
Trim34a,Mid1,Trim12c,Pcgf5,Trim13,Bfar,Rnf114,Dtx3l,Rnf24,Pml,Traf2,Traf5,Ankib1,Rnf145,Rnf19a,Dtx2,Trim26,Birc3,Nfxl1,Rffl,Znrf3,Mdm2,Rnf34,Rnf135,Trim30d,Rnf14,Cop1,Trim21,Cnot4,Trim36,Trim30a,Birc2,Mul1,Trim56,Trim12a,Rnf19b,Rnf139,Znrf1 |
| 6.691e-05 | -9.61 | phosphoric ester hydrolase activity | molecular function | GO:0042578 | 356 | 45 | 20217 | 1400 |
Ppp2r1b,Samhd1,Mtmr14,Ppp2r5a,Ptprj,Minpp1,Plpp1,Hmox1,Dusp5,Ccr1,Dusp16,Plcl2,Ppp2r2a,Dusp4,Dusp14,Pde5a,Inpp1,Nt5c3,Ccl5,Pde1b,Acpp,Pde4b,Dusp1,Ptpn2,Phlpp2,Ppm1l,Pde3b,Acp5,Dusp2,Dusp28,Phlpp1,Inpp5b,Plpp3,Ppm1k,Dusp6,Acp2,Eya4,Pde7b,Cnp,Mppe1,Ubash3b,Pfkfb3,Dusp8,Smpdl3b,Prkar2b |
| 6.694e-05 | -9.61 | detoxification | biological process | GO:0098754 | 63 | 14 | 20694 | 1406 |
Selenow,Abcb1a,Srxn1,Prdx5,Gsta3,Sod2,Mt2,Esd,Prdx1,Slc30a1,Mt1,Nqo1,Hp,S100a8 |
| 6.768e-05 | -9.60 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | biological process | GO:0035872 | 8 | 5 | 20694 | 1406 |
Irgm2,Nfkbia,Nod2,Ripk2,Rnf34 |
| 6.768e-05 | -9.60 | regulation of xenophagy | biological process | GO:1904415 | 8 | 5 | 20694 | 1406 |
Tlr2,Nod2,Nod1,Optn,Ripk2 |
| 6.768e-05 | -9.60 | negative regulation of lipopolysaccharide-mediated signaling pathway | biological process | GO:0031665 | 8 | 5 | 20694 | 1406 |
Trib1,Tnfaip3,Prdm1,Nfkbil1,Acod1 |
| 6.768e-05 | -9.60 | positive regulation of xenophagy | biological process | GO:1904417 | 8 | 5 | 20694 | 1406 |
Tlr2,Ripk2,Optn,Nod1,Nod2 |
| 6.768e-05 | -9.60 | autocrine signaling | biological process | GO:0035425 | 8 | 5 | 20694 | 1406 |
Cx3cl1,Hilpda,Cx3cr1,S100a8,Fzd1 |
| 6.768e-05 | -9.60 | ectopic germ cell programmed cell death | biological process | GO:0035234 | 8 | 5 | 20694 | 1406 |
Il1b,Il1a,Casp4,Kitl,Casp2 |
| 6.787e-05 | -9.60 | regulation of lipid biosynthetic process | biological process | GO:0046890 | 168 | 26 | 20694 | 1406 |
Il1b,Nr1h3,Fabp3,Trib3,Gfi1,C3,Acsl5,Sirt1,Htr2a,Egr1,Pcx,Nfkb1,Htr2b,Sphk1,Igf1r,Ldlr,Bmp2,Pla2g4a,Fpr2,Adora2b,Nr3c1,Tnf,Ptgs2,Il1a,Tspo,Pdgfb |
| 6.789e-05 | -9.60 | pyrophosphatase activity | molecular function | GO:0016462 | 795 | 84 | 20217 | 1400 |
Rap2c,Kif3c,Rhou,Ddx58,Kif9,Rab10,Rhoc,Gng4,Gna15,Rras2,Iigp1,Mx1,Gem,Rnd1,Rab20,Mcm6,Myo1b,Ifih1,Hspa2,Mov10,Tuba4a,Mx2,Rhof,Hspa1a,Gbp2b,Arl4a,Rab9,Gbp8,Tgtp1,Fignl2,Gbp9,Dync1h1,Adprm,Tap2,Gm12185,Igtp,Gm5431,Rnd3,Ppa1,Dcp2,Mcm9,Dhx58,Tor3a,Nkiras1,Dync1i2,Gbp2,Abcb1a,Gng11,Ddx4,Chd9,Helz2,Abcc1,Atp13a1,Ep400,Katna1,Tap1,9930111J21Rik1,Rab32,Myo10,Ifi47,Gnb4,Gm4841,Ift22,Gbp3,Rhoh,Gm4951,Ascc3,Cenpe,Gbp7,Rab21,Tgtp2,Gng12,Rhoq,Rab19,Gtpbp2,F830016B08Rik,Kif5c,Hspa1b,Irgm2,Gch1,Abcc5,Rac3,Irgm1,Enpp4 |
| 6.820e-05 | -9.59 | GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN | 136 | 25 | 15632 | 1249 |
Aff1,Cd164,Il1a,Kmo,Usp25,Kremen1,Kdm5b,Aftph,Dennd1b,Fut8,Itpr1,Hivep2,Parp8,Klf3,Ap3m2,Ppfibp2,Fmnl2,Tnip1,Znrf1,Tapbpl,Azi2,Fcho2,Atxn7l1,Itgal,Lcp2 |
| 6.835e-05 | -9.59 | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE | MSigDB lists | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE | 75 | 17 | 15632 | 1249 |
Cx3cl1,Sdc1,Psmb6,Col18a1,Tpi1,Ldha,Pgk1,Actb,Prdx1,Vcam1,Sdc4,Eno1,Agrn,Psat1,Psma6,Phactr4,Cp |
| 6.847e-05 | -9.59 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | 97 | 20 | 15632 | 1249 |
Psmb6,Psme1,H2-Q7,Psmb10,Fcgr1,Sec24a,Sec24b,Tap1,Itgav,Lnpep,H2-Q4,Psmb8,Psmb9,Psmd10,Tap2,H2-Q6,Psme2,Abcb1a,Tapbp,Psma6 |
| 6.881e-05 | -9.58 | GO_LYMPHOCYTE_COSTIMULATION | MSigDB lists | GO_LYMPHOCYTE_COSTIMULATION | 68 | 16 | 15632 | 1249 |
Rictor,H2-Aa,Icosl,Cd274,Cav1,Tnfsf14,Cd86,H2-Eb1,Src,Spn,Tnfrsf14,Cd80,Lyn,Map3k8,H2-Ab1,Tnfsf4 |
| 6.889e-05 | -9.58 | regulation of organic acid transport | biological process | GO:0032890 | 79 | 16 | 20694 | 1406 |
Irs2,Tnf,P2ry2,Adora2a,Il1a,Syk,Stxbp1,Edn1,Arg2,Fabp3,Acsl5,Kmo,Il1b,Il1rn,Thbs1,Nr3c1 |
| 6.898e-05 | -9.58 | hydrolase activity | molecular function | GO:0016787 | 2431 | 215 | 20217 | 1400 |
Dync1h1,Dusp4,Rnaset2a,Hdac1,Zc3h12c,Plaat3,Gbp8,Arl4a,Dhx58,Nkiras1,Igtp,Ppa1,Cd38,Mcm9,Tap2,Xrn1,Ppp2r1b,Gem,Kif9,Gna15,Ago3,Kif3c,Rhou,Tank,Cpd,Adar,Mov10,Ifih1,Plcl2,Rab20,Mcm6,Ccr1,Endod1,Zbp1,Rhoq,Acp2,Rab21,Gng12,Zc3h12a,Gbp7,Usp25,Vcpip1,Gch1,Irgm2,Ptpn2,Ep400,Rhbdf2,Arg2,Pde4b,Usp42,Pde3b,Abcc1,Pla2g4a,Cflar,Gng11,Gm4951,Gda,Ppm1k,Psmb10,Gnb4,Lipg,Rab32,Pde5a,Fignl2,Slfn9,Ppp2r2a,Usb1,Rhof,Rab9,Noct,Tor3a,Lipe,Ddhd1,Aoah,Dcp1a,Samhd1,Htra1,Rab10,Rhoc,Gng4,Ddx58,Casp2,Usp31,Ptprj,Tuba4a,Minpp1,Casp3,Rbbp8,Tgtp2,Ascc3,Hp,Pfkfb3,F830016B08Rik,Ubash3b,Prkar2b,Hspa1b,Dusp1,Tap1,Mmp9,Acp5,Helz2,Fgl2,Gbp2,Phlpp1,Psma6,Inpp5b,Ift22,Rhoh,Gbp3,Ifi47,Gm4841,Casp8,Usp53,Plau,Gbp9,Dusp14,Inpp1,Uchl1,Tgtp1,Casp4,Gbp2b,Asah2,Gm5431,Dcp2,Gm12185,Pde1b,Psmb6,Plat,Iigp1,Rras2,Mmp25,Mx1,Usp12,F10,Mtmr14,Usp35,Adgb,Rap2c,Mx2,Slfn8,C1ra,Hspa2,Hmox1,Sap30,Casp7,Cenpe,Mmp14,Psmb8,Mmp13,Mppe1,Gbe1,Rac3,Irgm1,Kif5c,Sirt1,Katna1,Atp13a1,Nod2,Dync1i2,Chd9,Abcb1a,Pla2g7,Ddx4,Otud1,C1rl,Dusp28,Esd,Apobec3,Adprm,Ampd3,Hspa1a,Rnaset2b,Ccl5,Nt5c3,Usp18,Rnd3,Adam19,Malt1,Dnase1l3,Ctsc,Cemip2,Casp1,Ppp2r5a,Plpp1,Bst1,Rcl1,Dusp16,Myo1b,Dusp5,Rnd1,Dusp6,Eya4,Zup1,Cnp,Enpp4,Pde7b,Abcc5,Lap3,Smpdl3b,Dusp8,Pnpt1,Rab19,Isg20,Gtpbp2,Tnfaip3,Acpp,Dusp2,Ppm1l,Phlpp2,Mthfd2,Lnpep,Plpp3,Psmb9,9930111J21Rik1,Myo10 |
| 6.903e-05 | -9.58 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | 169 | 29 | 15632 | 1249 |
Plat,Dram1,Il18,Map3k8,Nr4a3,Lox,Btg2,Pstpip2,Pdgfb,St3gal5,Tlr1,Tmem176a,Jarid2,Ltbp2,Cnp,Slc7a2,Ahr,Olfml3,Nfkbiz,Tmem176b,Cx3cl1,Isg15,Ifih1,Il4ra,Ifi44,C1ra,Cebpd,Fam43a,Arhgef3 |
| 6.972e-05 | -9.57 | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP | 186 | 31 | 15632 | 1249 |
Myd88,Gbp2,H2-Q7,Irf2,Mthfr,Tpi1,Pgm1,Ddx58,Kat2b,Errfi1,Il18bp,Nod2,Dhx58,Parp9,Rab32,H2-Q4,H2-Q6,Csf3r,Fam102b,Plcl2,Jak2,Ifi35,Mcm6,Spire1,Fam111a,Rcsd1,Il2rg,Trim21,Alas1,Hk1,Mov10 |
| 6.984e-05 | -9.57 | cellular response to exogenous dsRNA | biological process | GO:0071360 | 17 | 7 | 20694 | 1406 |
Tlr3,Ifih1,Zc3hav1,Mul1,Cav1,Ddx58,Cgas |
| 6.994e-05 | -9.57 | reproductive structure development | biological process | GO:0048608 | 429 | 51 | 20694 | 1406 |
Tiparp,Sirt1,Axl,Notch1,Hmga2,Crkl,Gja1,Itgav,Spint2,Inhba,Ahr,Ccnd1,Src,Bcl2l11,Map2k1,Atm,Pdgfb,Lif,Htra1,Hif1a,Nos2,Ptgs2,Serpinb6b,Itga4,Insl6,Arid5b,Fzd5,Junb,Kdm5b,Fndc3a,Igf1r,Vcam1,Birc2,Notch2,Serpine1,Nupr1,Icam1,H3f3b,Prdm1,Met,Angpt1,Il10,Plaur,Pla2g4a,Cited2,Kdr,Socs3,Arid4a,Tnc,Kitl,Stat5a |
| 7.007e-05 | -9.57 | CARD domain binding | molecular function | GO:0050700 | 12 | 6 | 20217 | 1400 |
Ripk2,Casp1,Casp4,Nod1,Irgm2,Nod2 |
| 7.178e-05 | -9.54 | GSE12003_4D_VS_8D_CULTURE_BM_PROGENITOR_UP | MSigDB lists | GSE12003_4D_VS_8D_CULTURE_BM_PROGENITOR_UP | 161 | 28 | 15632 | 1249 |
Clic4,Notch2,Cdkn1a,Pfkl,Tagap,Slc25a22,Lyn,Mmp25,Adora2b,Ptgs2,Spen,Btg2,Ppp2r3a,Eef1e1,Hk2,Bst1,Eno2,Mthfd1l,Cd274,Plk3,Socs1,Gbp9,Gbp4,Kdm5b,Taf4b,Dusp1,Slc2a1,Dock4 |
| 7.178e-05 | -9.54 | GSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_UP | MSigDB lists | GSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_UP | 161 | 28 | 15632 | 1249 |
Dgkh,Ptger4,Rac3,Il15ra,Cmklr1,Cd274,Samsn1,Sik3,Dcun1d3,Il18rap,Tyk2,Csf1,Phlpp2,Icam1,Xrn1,Itga4,Nek6,Rgs3,Apaf1,Crim1,Slc28a2,Nod1,Traf5,Mapkbp1,Slamf7,Ttc39c,Cx3cr1,Klf3 |
| 7.178e-05 | -9.54 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP | 161 | 28 | 15632 | 1249 |
Socs3,Rcsd1,Fam111a,Irf1,Pim1,Rgs1,Snn,Pde4b,Itgal,Piezo1,Ddit4,Maff,Rap1gap2,Mmd,Tpi1,Evl,Nfkbiz,Irs2,Ubash3b,Samhd1,Abcc5,Dusp1,Jun,Cited2,Fos,Otud1,Prkce,Tnfsf8 |
| 7.248e-05 | -9.53 | positive regulation of cold-induced thermogenesis | biological process | GO:0120162 | 96 | 18 | 20694 | 1406 |
Igf1r,Syk,Dync1h1,Acsl1,Jak2,Cmklr1,Gja1,Il4ra,Cav1,Gadd45g,Adrb2,Plac8,Il18,Irf4,Pdgfc,Lcn2,Dio2,Kdm6b |
| 7.248e-05 | -9.53 | regulation of phosphatidylinositol 3-kinase signaling | biological process | GO:0014066 | 96 | 18 | 20694 | 1406 |
Osm,Ccl5,Tnf,Igf1r,Pdgfb,Fgr,Kdr,Flt1,Jak2,Ptk2,Rasgrp1,Hcls1,Angpt1,Il18,Csf3,Sirt1,Pdgfc,Pdgfrb |
| 7.315e-05 | -9.52 | positive regulation of cell cycle process | biological process | GO:0090068 | 248 | 34 | 20694 | 1406 |
Rgcc,Prkce,Cdk5r1,Ccnd1,Pbx1,Pkp4,Crlf3,Dync1h1,Phip,Edn1,Igf1r,Ube2e2,Hspa2,Ankrd17,Sphk1,Il1b,Gpsm2,Pdgfrb,Mdm2,Tmod3,Il1a,Smc5,Tnf,Cenpj,Cenpe,Ccnd2,Pdgfb,Mecp2,Pml,Casp2,Ccne1,Cdkn1a,Met,Prdm9 |
| 7.345e-05 | -9.52 | GSE17721_4_VS_24H_GARDIQUIMOD_BMDC_UP | MSigDB lists | GSE17721_4_VS_24H_GARDIQUIMOD_BMDC_UP | 178 | 30 | 15632 | 1249 |
Ifnar1,Klf6,Gadd45b,Csf3r,Ccdc86,Dbnl,Batf2,Il4i1,Stk40,Rhoh,Atf3,Psme1,Gmppb,Cd74,Upp1,Rnd3,Ccnj,Cd86,Lcp2,St3gal5,Sap30,Maff,Tbc1d13,Denr,Trib1,Mob3b,Serpinb2,Plcl2,Il1b,Snn |
| 7.345e-05 | -9.52 | GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN | MSigDB lists | GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN | 178 | 30 | 15632 | 1249 |
Fndc3a,Dyrk2,Tlr3,Gfi1,Il15ra,Gcnt2,Bambi,Dr1,Plcl2,Serpine1,Rrs1,Gna15,Lcp2,Psd4,Nampt,4930523C07Rik,Slc31a2,Spint2,Kctd12,Ext1,Sell,Ciapin1,Cd180,Ier2,Plau,Rsad2,Cox17,Nfkbie,Cp,Casp3 |
| 7.351e-05 | -9.52 | cell development | biological process | GO:0048468 | 1748 | 159 | 20694 | 1406 |
Il6,Atm,Cyfip1,Hif1a,Cflar,Vasp,Mturn,Phgdh,Lox,Jag1,Nrp2,Lhx2,Rapgef2,Cdyl,Casp2,Sema4a,Rap2c,Bmp2,Marf1,Dbnl,Itgav,Htr2b,Gja1,Ptch1,F11r,Casp3,Chst11,Zmynd15,Klf7,Lyn,Nr4a3,Spire1,Cdk5r1,Myadm,Sdc1,Arf4,Csrp1,Fam20c,Btg2,Palld,Axl,Fubp1,Diaph2,Il1b,Cited2,Stxbp1,Egr2,Kdr,Kitl,Sod2,Jun,Il1a,Prdm1,H3f3b,Myd88,Met,Sdc4,Fcgr2b,Taf4b,Etv5,Igf1r,Fndc3a,Psd,Clic4,Tmem67,Ext1,Jmjd6,Uchl1,Notch2,Icam1,Rab10,Gdf15,Arid5b,Insl6,Bcl6,Plod3,Sec24b,Col27a1,Ednrb,Actb,Slc4a7,C3,Rcan1,Pou3f1,Mark2,Rnd1,Agrn,Lif,Pdgfb,Dst,Scn1b,Rilpl1,Lrp4,Tmod3,Tut7,Sema3c,Casp4,Map4k4,Src,Clec5a,Lst1,Micall2,Hap1,Fpr2,Map2k1,Dock10,Crkl,Flnb,Tdrd7,Spint2,Jak2,Flrt3,Inhba,Tlr2,Dnase1l3,Pou2f2,Sgcb,Notch1,Scarf1,Phactr4,Mecp2,Abcb1a,Arid4a,Tnc,Kif5c,Ehd1,Adora2a,Evl,Adgrg6,Ezr,Cnp,S100a8,Map2k4,Sdc2,Acvr1,Klf2,Trip13,Hspa2,Antxr1,Sema4c,Homer1,Ntng2,Tsku,Edn1,Triobp,Flrt2,Igsf9,Frmd6,Col18a1,Fas,Il15,Lrp8,Itga4,Pdgfrb,Fzd5,Ptk2,Nectin2,Clic5,Rac3 |
| 7.376e-05 | -9.51 | GAVIN_FOXP3_TARGETS_CLUSTER_P4 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P4 | 90 | 19 | 15632 | 1249 |
Mxd1,Plagl1,Pim1,Map3k8,Ppm1l,St3gal6,Sema4a,Sh3bgrl2,Osbpl3,Cd83,Nfil3,Myo10,Gadd45b,Tnfrsf1b,Swap70,Hopx,Hspa1a,Mmd,Stx11 |
| 7.404e-05 | -9.51 | hydrolase activity, acting on acid anhydrides | molecular function | GO:0016817 | 797 | 84 | 20217 | 1400 |
9930111J21Rik1,Myo10,Rab32,Ifi47,Gnb4,Gm4841,Ift22,Rhoh,Gbp3,Gm4951,Gbp2,Dync1i2,Chd9,Gng11,Ddx4,Abcb1a,Helz2,Abcc1,Ep400,Atp13a1,Tap1,Katna1,Rab19,Gtpbp2,Kif5c,F830016B08Rik,Gch1,Hspa1b,Irgm2,Irgm1,Abcc5,Rac3,Enpp4,Cenpe,Ascc3,Gbp7,Rab21,Gng12,Tgtp2,Rhoq,Rab20,Mcm6,Rnd1,Ifih1,Myo1b,Hspa2,Mov10,Tuba4a,Mx2,Rhou,Kif3c,Rap2c,Ddx58,Rab10,Kif9,Rhoc,Gna15,Gng4,Iigp1,Rras2,Gem,Mx1,Tap2,Gm12185,Gm5431,Igtp,Rnd3,Ppa1,Dcp2,Mcm9,Dhx58,Nkiras1,Tor3a,Gbp2b,Hspa1a,Rhof,Arl4a,Rab9,Gbp8,Tgtp1,Fignl2,Dync1h1,Gbp9,Adprm |
| 7.404e-05 | -9.51 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | molecular function | GO:0016818 | 797 | 84 | 20217 | 1400 |
Gng4,Gna15,Rab10,Kif9,Rhoc,Gem,Mx1,Iigp1,Rras2,Kif3c,Rhou,Rap2c,Ddx58,Tuba4a,Mov10,Mx2,Rab20,Mcm6,Rnd1,Hspa2,Ifih1,Myo1b,Fignl2,Adprm,Dync1h1,Gbp9,Arl4a,Gbp8,Rab9,Hspa1a,Gbp2b,Rhof,Tgtp1,Ppa1,Rnd3,Dcp2,Mcm9,Gm5431,Igtp,Nkiras1,Tor3a,Dhx58,Tap2,Gm12185,Ep400,Atp13a1,Tap1,Katna1,Chd9,Gng11,Abcb1a,Ddx4,Gbp2,Dync1i2,Abcc1,Helz2,Rhoh,Gbp3,Ift22,Gm4951,Myo10,Rab32,9930111J21Rik1,Gnb4,Gm4841,Ifi47,Rhoq,Gbp7,Cenpe,Ascc3,Gng12,Tgtp2,Rab21,Irgm1,Abcc5,Rac3,Enpp4,Gtpbp2,Rab19,Gch1,Hspa1b,Irgm2,Kif5c,F830016B08Rik |
| 7.414e-05 | -9.51 | VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | MSigDB lists | VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | 153 | 27 | 15632 | 1249 |
Sod2,Pik3r5,Axl,Bcl6,Msr1,Dse,Il6,Chst11,Vcan,Plau,Gnb4,Pdgfc,Ltbp2,Snx10,Plod2,Antxr1,Akt3,Ociad1,Inhba,Pla2g7,H2-Ab1,St3gal1,Lox,Tlr2,Thbs1,Rbms1,Frmd6 |
| 7.417e-05 | -9.51 | LIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK | MSigDB lists | LIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK | 15 | 7 | 15632 | 1249 |
Nrp2,Htra1,Jag1,Pla2g7,Mmd,Il2rg,St3gal6 |
| 7.417e-05 | -9.51 | GO_POSITIVE_REGULATION_OF_INTERFERON_ALPHA_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERFERON_ALPHA_PRODUCTION | 15 | 7 | 15632 | 1249 |
Zc3hav1,Irf7,Ifih1,Ddx58,Ripk2,Tlr3,Tlr9 |
| 7.417e-05 | -9.51 | GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS | 15 | 7 | 15632 | 1249 |
Il10,Cav1,Zc3h12a,Atp2b4,Tspo,Cd34,Stat3 |
| 7.417e-05 | -9.51 | PID_INTEGRIN5_PATHWAY | MSigDB lists | PID_INTEGRIN5_PATHWAY | 15 | 7 | 15632 | 1249 |
Sdc1,Itgav,Itga4,Plaur,Itgb8,Vcam1,Plau |
| 7.417e-05 | -9.51 | MARKS_HDAC_TARGETS_DN | MSigDB lists | MARKS_HDAC_TARGETS_DN | 15 | 7 | 15632 | 1249 |
Stat5a,Tnf,Hif1a,Cflar,Il6,Ccnd1,Il1b |
| 7.417e-05 | -9.51 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | MSigDB lists | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | 15 | 7 | 15632 | 1249 |
Map2k4,Tab2,Ripk2,Ikbkg,Nod2,Irak2,Nod1 |
| 7.428e-05 | -9.51 | ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF | 42 | 12 | 15632 | 1249 |
Ccnj,Egr3,Egr1,Tagln,Chic2,Sphk1,Cited2,Clcf1,Rnf24,Cdc42ep2,Inhba,Errfi1 |
| 7.433e-05 | -9.51 | GO_HOMEOSTATIC_PROCESS | MSigDB lists | GO_HOMEOSTATIC_PROCESS | 1242 | 136 | 15632 | 1249 |
Jak2,Ldlr,Tlr9,Rac3,Lpar1,Cacnb3,Rab20,Lyn,Csf1,Slc9a1,Med13,Atm,S100a8,Ednrb,Hk1,Sco1,Cav1,Nos2,Cd34,Slc16a1,Hk3,Fas,Slc30a1,Irs2,Nr1h3,Pla2g4a,Sod2,Ptpn2,Gcnt2,Htr2b,Il1b,Parp3,Slc31a1,Hmox1,Nr4a3,Inhba,Ccr1,Pde4b,Gja1,Ccl5,Tap2,Vps54,Atp6v1d,Sgk3,Lipg,Cutc,Cd38,Stau1,Tnfaip3,Slc39a13,Fabp3,Stat3,Slc39a4,Cp,Prdx5,Slc25a37,Txnrd1,Homer1,Bcl6,Actb,Hcls1,Prkar2b,Xcr1,Nox1,Tmod3,Stat1,Adrb2,Mafg,Ampd3,Oas1a,Sirt1,Slc39a14,Pdk3,Tnfsf14,Gna15,Ptch1,Lcn2,P2ry2,Plau,Prdx1,Fbxo4,Htr2a,Gclc,Adar,Atp2b4,Chmp4b,Tap1,Tnks1bp1,Tmtc2,Prnp,Ccr3,Kcnj2,Edn1,Ikzf1,Prkce,Myc,Il6,Ccl2,Nod2,Ncoa5,Ifit1bl1,Ccl12,Bcl2l11,Tet2,Clic4,Glrx,Hcar2,Ptger4,Cd55,Oas1g,Smc5,Grina,Hk2,Slc31a2,Slc4a7,Txn1,Arid4a,Slc7a8,Ifit1bl2,Klf2,Ripk3,Slc30a4,Pml,Hif1a,Icam1,Il1a,Jmjd6,Casp3,Gsr,Atp13a1,Ehd1,Src,Axl,Itpr1,Swap70,Cd40 |
| 7.489e-05 | -9.50 | positive regulation of blood vessel endothelial cell migration | biological process | GO:0043536 | 56 | 13 | 20694 | 1406 |
Akt3,Plk2,Thbs1,Sirt1,Angpt1,Stat5a,Ptgs2,Hmox1,Vegfc,Pdgfb,Cd40,Kdr,Hif1a |
| 7.489e-05 | -9.50 | negative regulation of response to oxidative stress | biological process | GO:1902883 | 56 | 13 | 20694 | 1406 |
Glrx,Txn1,Il10,Hk3,Sirt1,Met,Hsph1,Nr4a3,Slc7a11,Fzd1,Ncoa7,Sod2,Hif1a |
| 7.511e-05 | -9.50 | SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_UP | MSigDB lists | SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_UP | 36 | 11 | 15632 | 1249 |
Slpi,Pdpn,Junb,S100a8,Gch1,Srm,Rbms1,Ralgds,Adar,Odc1,Il4ra |
| 7.511e-05 | -9.50 | SHIN_B_CELL_LYMPHOMA_CLUSTER_8 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_8 | 36 | 11 | 15632 | 1249 |
Nfkbia,Hdac1,Mafk,Nfkbib,Icam1,Lyn,Fas,Stat1,Cd38,Il15,Cd80 |
| 7.522e-05 | -9.50 | HADDAD_B_LYMPHOCYTE_PROGENITOR | MSigDB lists | HADDAD_B_LYMPHOCYTE_PROGENITOR | 248 | 38 | 15632 | 1249 |
Zhx2,Snn,Glrx,Pik3cd,Arid5b,Cacnb3,Dck,Dyrk2,Rasgrp1,Cd69,Snx2,Btg2,Isg20,Rims3,Cav1,Map4k4,Tuba4a,Atm,Ppfibp1,Crim1,Ciita,Irs2,P2ry14,Kat2b,Il1a,Dcp2,Irf2,Gadd45g,Irf4,Kcnj2,Tcf4,Cited2,Jun,Itpr1,Sod2,Plekhf2,Ezr,P4ha2 |
| 7.532e-05 | -9.49 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | 321 | 46 | 15632 | 1249 |
Slc16a1,Egr1,Lrp8,Aldh1b1,Nlrp3,Pttg1,Myc,Chst11,Taf4b,Ezr,Tiparp,Cited2,Dnaja1,Fos,Idi1,Ldlr,Pim2,Itga5,Hmgcs1,Tlr2,Acsl1,Trip13,Slc39a14,Ccne1,Psat1,Ahsa1,Gnb4,Tnfaip3,Cd38,Etv5,Mcm10,Itga4,Cd180,Hsph1,Tnf,Ehd1,Hspa1a,Slc2a1,Lacc1,Mcm6,Pim1,Slc7a5,Phlda1,Dusp6,Tuba4a,Ccr1 |
| 7.543e-05 | -9.49 | GO_PROTEIN_MATURATION | MSigDB lists | GO_PROTEIN_MATURATION | 257 | 39 | 15632 | 1249 |
S100a8,Ptch1,Casp8,Mndal,Ifi211,Tnfsf15,Ifi208,Ifi203,Egln3,Casp2,Casp7,Ifi204,Jak2,Tnfsf10,Plat,Fam162a,Ifi213,Tnf,Casp1,Bcl2l11,Traf2,Nlrc4,Ifi205,Rhbdf2,Ifi209,Casp3,Cycs,Mmp14,Ift57,Cpd,Fas,Pml,Ifi214,Mul1,Nlrp3,F10,Nod1,Ifi207,Apaf1 |
| 7.596e-05 | -9.49 | Type I diabetes mellitus | KEGG pathways | mmu04940 | 68 | 17 | 7931 | 713 |
H2-T22,H2-Q4,H2-Q7,H2-M2,Cd86,H2-Q6,Cd80,H2-Aa,H2-T24,H2-Ab1,Il1a,Fas,Il12b,H2-Eb1,Il1b,Tnf,H2-T10 |
| 7.596e-05 | -9.49 | Type I diabetes mellitus | KEGG pathways | ko04940 | 68 | 17 | 7931 | 713 |
H2-Q4,H2-T22,Tnf,H2-Eb1,Il1b,Il12b,H2-T10,Il1a,H2-Ab1,Fas,Cd80,H2-T24,H2-Aa,H2-Q7,H2-Q6,Cd86,H2-M2 |
| 7.644e-05 | -9.48 | GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | MSigDB lists | GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | 891 | 103 | 15632 | 1249 |
Col4a2,Cd34,Sdc4,Gpc1,Col18a1,Cx3cl1,Cdk5r1,Pikfyve,Dusp2,Mmp14,Phactr4,Dusp4,Ift57,Nr4a1,Itgav,Syk,Cited2,Ets2,Rpgrip1l,Lhx2,Sema4c,Ptk2,Egr3,Itga5,Mmp9,Atm,Cav1,Sema3c,Lmo4,Rab3ip,Apaf1,Tulp3,Sat1,Hdac1,Txnrd1,Bcl6,Csf3r,Nfkb2,Hmox1,Il18,Nr4a3,Nrp2,Inhba,Fzd1,Vasp,Ppp2r3a,Fzd5,Hopx,Serpine1,Atp6v1d,Pdgfrb,Map2k1,Plau,Pde3b,Angpt1,Edn1,Pdpn,Flt1,Bcl2l11,Ccl12,Jun,Tmem67,Cflar,Kdr,Fam20c,Tnfaip2,Socs7,Nox1,Tmod3,Sema4a,Htra1,Jag1,Sirt1,Ptch1,Notch1,Hhex,Itga4,Calcrl,Hif1a,Intu,Jmjd6,Casp3,Egr2,Acvr1,Acvrl1,Ehd1,Dusp1,Prkx,Clic4,Thbs1,Vegfc,Sec24b,Abcc4,Kdm6b,Zc3h12a,Dusp5,Ptgs2,Tgfbi,Wars,Snx10,Mthfd1l,Junb,Pik3r6 |
| 7.721e-05 | -9.47 | HALLMARK_UV_RESPONSE_DN | MSigDB lists | HALLMARK_UV_RESPONSE_DN | 137 | 25 | 15632 | 1249 |
Atp2b4,Rnd3,Cited2,Dusp1,Rbpms,Sdc2,Prkce,Myc,Nr3c1,Pik3cd,Adora2b,Lpar1,Abcc1,Prkar2b,Igf1r,Ldlr,Notch2,Sipa1l1,Pdgfrb,Serpine1,Cav1,Nfkb1,Gja1,Met,Akt3 |
| 7.721e-05 | -9.47 | RELA_DN.V1_UP | MSigDB lists | RELA_DN.V1_UP | 137 | 25 | 15632 | 1249 |
Egr3,Gpr85,Ptgs2,Snapc1,Il1b,Agpat4,Junb,Fosb,Samsn1,Ppp1r15a,Zfp36,Zfp324,Egr1,Atf3,Kmo,Cd38,Ccl12,Gadd45b,Klf6,Tank,Jun,Fos,Dusp8,Tnc,Pde5a |
| 7.731e-05 | -9.47 | GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_DN | MSigDB lists | GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_DN | 187 | 31 | 15632 | 1249 |
Slc30a4,St3gal6,Sgcb,Cenpe,Ehd1,Syk,Tet2,Gpsm2,Hspa1a,Fcgr2b,Errfi1,Tmod3,Rcn1,Osbpl3,Irak2,Lhx2,Cdkn1a,Glrx,Frmd6,4930523C07Rik,Txn1,Ccl5,Hopx,Cd86,Med21,Gem,Gbp7,Arl5b,Slc39a14,Rap1gap2,Hk2 |
| 7.731e-05 | -9.47 | GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | 187 | 31 | 15632 | 1249 |
Arhgef3,Tspan3,Gypc,Parp9,Tnfsf8,Dusp2,Casp3,Nr3c1,Psme1,Fas,Itga4,Mdfic,Apaf1,Slamf7,Pnpt1,Traf5,Nampt,Syne2,Rasgrp1,Pou2f2,Hivep3,Stat4,Tapbpl,Rcsd1,Pik3cd,Osgin2,Irf1,Hmgcs1,Vrk2,Tcea1,Asf1a |
| 7.731e-05 | -9.47 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP | 187 | 31 | 15632 | 1249 |
Pdss1,Atxn7l1,Nmi,Eef1e1,S100a8,Tap2,Cnp,Cd86,Mov10,Lgals9,Osbpl3,Idi1,Rgs1,Epsti1,Hsd17b7,Casp7,Herc6,Rnf19b,Serpinb9,Phgdh,1110038F14Rik,Treml2,Rsad2,Tapbp,Rnf114,Il15,Gpc1,Ncoa7,Rbl1,Mvp,Tpi1 |
| 7.731e-05 | -9.47 | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN | MSigDB lists | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN | 187 | 31 | 15632 | 1249 |
Gbp2,Rbms2,Gbp3,Tpi1,Plk3,Atf3,Cd200r4,Slc15a3,Ccdc86,Ccl2,Mmp14,Fcgr2b,Msr1,Ccl12,Fam162a,Ccl4,Ikbke,Tnfsf10,Rbms1,Serpinb9,Pdzd11,Ier3,Rcn1,Psmb6,AA467197,Cxcl2,Cd69,Car13,Slc39a14,Psat1,Nampt |
| 7.751e-05 | -9.47 | regulation of DNA damage response, signal transduction by p53 class mediator | biological process | GO:0043516 | 35 | 10 | 20694 | 1406 |
Sirt1,Atm,Mdm2,Kmt5a,Spred1,Eef1e1,Spred3,Psmd10,Cd74,Pmaip1 |
| 7.759e-05 | -9.46 | GO_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY | MSigDB lists | GO_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY | 55 | 14 | 15632 | 1249 |
Nos2,Pik3r6,H2-Q6,Ccl12,H2-Q4,Rasgrp1,Il12rb1,Stap1,Serpinb9,Il12b,Icam1,H2-Q7,Tap1,Ripk3 |
| 7.826e-05 | -9.46 | Interleukin-4 and 13 signaling | REACTOME pathways | R-MMU-6785807 | 14 | 7 | 8608 | 757 |
Stat3,Il13ra1,Jak2,Tyk2,Il4ra,Il2rg,Stat1 |
| 7.830e-05 | -9.45 | MORI_MATURE_B_LYMPHOCYTE_UP | MSigDB lists | MORI_MATURE_B_LYMPHOCYTE_UP | 83 | 18 | 15632 | 1249 |
Map2k1,Cd40,Rgs14,Arhgef3,Irf8,Slc4a7,H2-Aa,Sell,Adrb2,Il2rg,Map3k8,Cd74,Tmod3,Ebi3,Samhd1,Wdr43,Cd83,Jak2 |
| 7.830e-05 | -9.45 | GO_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | 83 | 18 | 15632 | 1249 |
Pdgfb,Edn1,Il6,Klf2,Pid1,Pdgfrb,Tnf,Ass1,Ripk3,Il1b,Cdkn1a,Plau,Jak2,Tspo,Thbs1,Icam1,Ptgs2,Zc3h12a |
| 7.830e-05 | -9.45 | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | 83 | 18 | 15632 | 1249 |
Odc1,Sema4a,Ppm1l,Ttc39b,Endod1,Cd38,Igf1r,Nod1,Cyfip1,Ankrd17,Itgav,Stat4,Stx11,Irf4,Btg2,Myc,Plscr1,Itgb8 |
| 7.966e-05 | -9.44 | NFKBTNSCPFCT | prints domains | PR00057 | 5 | 4 | 5821 | 374 |
Nfkb2,Relb,Nfkb1,Rel |
| 8.039e-05 | -9.43 | lymphocyte homeostasis | biological process | GO:0002260 | 64 | 14 | 20694 | 1406 |
Bcl2a1a,Bcl2l11,Pik3cd,Dock10,Pmaip1,Casp3,Ikbkg,Hif1a,Ahr,Ripk3,Fas,Tnfaip3,Lyn,Stat5a |
| 8.061e-05 | -9.43 | SRF_Q5_01 | MSigDB lists | SRF_Q5_01 | 196 | 32 | 15632 | 1249 |
Zfp513,Egr1,Mapkapk2,Ier2,Atf3,Abr,Tle3,Tagln,Cnn2,Klf6,Tank,Cited2,Fos,Egr2,Itgb8,Gadd45g,Mid1,Dusp5,Egr3,Thbs1,Actb,Pcdh7,Csrp1,Myadm,Junb,Fosb,Ptch1,Med13,Pdlim7,Ppp2r3a,Vasp,G3bp2 |
| 8.123e-05 | -9.42 | GO_REGULATION_OF_INTERLEUKIN_1_SECRETION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_1_SECRETION | 25 | 9 | 15632 | 1249 |
Nod2,Nlrp3,Pml,Ifnar1,Casp1,Zc3h12a,Aim2,Gsdmd,Ptger4 |
| 8.123e-05 | -9.42 | LU_TUMOR_ANGIOGENESIS_UP | MSigDB lists | LU_TUMOR_ANGIOGENESIS_UP | 25 | 9 | 15632 | 1249 |
Ccne1,Itgav,Mmp9,Ptk2,Ccnd2,Edn1,Jag1,Notch1,Vcan |
| 8.123e-05 | -9.42 | BIOCARTA_INFLAM_PATHWAY | MSigDB lists | BIOCARTA_INFLAM_PATHWAY | 25 | 9 | 15632 | 1249 |
Il15,Csf1,Il6,Csf3,Ifnb1,Tnf,Il1a,Il10,Il12b |
| 8.123e-05 | -9.42 | BIOCARTA_STRESS_PATHWAY | MSigDB lists | BIOCARTA_STRESS_PATHWAY | 25 | 9 | 15632 | 1249 |
Casp2,Traf2,Map2k4,Tank,Jun,Tnf,Nfkbia,Ikbkg,Nfkb1 |
| 8.123e-05 | -9.42 | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | MSigDB lists | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | 25 | 9 | 15632 | 1249 |
Cav1,Col18a1,Casp1,Il13ra1,Plaur,Met,Nqo1,Mvp,Nr3c1 |
| 8.133e-05 | -9.42 | MOOTHA_PGC | MSigDB lists | MOOTHA_PGC | 388 | 53 | 15632 | 1249 |
Fam162a,Stard7,Ifi204,Mthfd2,Ifi211,Alas1,Ifi203,Mndal,Lcn2,Ifi207,Me1,Tpi1,Cdkn2d,Mapkapk2,Ifi214,Cx3cl1,Ifrd1,Sod2,Fos,Gtpbp2,Pgk1,Glrx,Ldha,Slc31a1,Phyh,Ddit4,Ifi208,Phlda1,Scn1b,Inhba,Gdf15,Dusp6,Gch1,Atp6v1d,Pdgfrb,Map2k1,Crlf3,Gys1,Upp1,Psmb10,Jmjd6,Fabp3,Cycs,Sat1,Carhsp1,Psma6,Src,Ifi213,Dusp1,P4ha2,Eno1,Ifi209,Ifi205 |
| 8.164e-05 | -9.41 | GSE45365_WT_VS_IFNAR_KO_CD8A_DC_MCMV_INFECTION_UP | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_CD8A_DC_MCMV_INFECTION_UP | 179 | 30 | 15632 | 1249 |
Clec5a,Grina,Il2rg,Stat1,Rtn1,Filip1l,Tfec,Jak2,Pilrb1,Fscn1,Tax1bp1,Chd9,Tnfsf10,Higd1a,Casp8,Parp12,Tyk2,Icam1,Ddx60,Hck,Pilrb2,Sdc4,Plau,Smg7,Zyx,Tcf4,Hdac1,Tapbp,Scarf1,Ccl2 |
| 8.164e-05 | -9.41 | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP | MSigDB lists | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP | 179 | 30 | 15632 | 1249 |
Slc16a1,Batf,Plagl1,Icam1,Nmral1,Fas,Gsr,B3gnt5,Psma6,Cox17,Cish,D1Ertd622e,Cited2,Hmga1,Ttc39c,Srm,Gadd45b,P4ha2,Cdkn1a,Idi1,Ldlr,Osbpl3,Nr4a3,Stx11,Sap30,Ksr1,Lmo4,Irf8,Asns,Jdp2 |
| 8.164e-05 | -9.41 | GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_DN | MSigDB lists | GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_DN | 179 | 30 | 15632 | 1249 |
Irf7,Ifit1bl2,Eno2,Tdrd7,Spint2,Oas2,Oas1a,Rtn2,Htra1,Trim14,Ext1,Oas1g,Oasl1,Herc6,Oas3,B4galt4,Abcc5,Lrp4,Apobec3,Ifit1bl1,Dpy19l1,Hspa2,Ifi44,Isg15,Usp18,Ddx58,Sdc1,Palld,Gpc1,Myd88 |
| 8.164e-05 | -9.41 | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | 179 | 30 | 15632 | 1249 |
Aim2,Cyth3,Il15,Foxp4,Itgav,Plekha5,Aoah,Bcl6,Dennd1b,Dusp2,Nr3c1,Slfn8,Chst11,Lyn,Fcho2,Chd9,Slfn9,Thbs1,Slfn3,Cflar,Ccl5,Snx10,H2-Eb1,Plekha2,C1rl,Lcp2,Slfn4,Wdfy1,Ube2l6,Rnf19a |
| 8.164e-05 | -9.41 | GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_DN | 179 | 30 | 15632 | 1249 |
B3gnt5,Gpr68,Glipr2,Ctsc,Tspan3,Arhgef3,Pik3r5,Cnn2,Klf6,Plac8,Tnfaip3,Crlf3,St3gal6,Sell,Tab2,Kat2b,Dgka,Vps54,Cnp,Lcp2,Card6,Lnpep,5430427O19Rik,Lrrc8c,Slc37a3,Cldnd1,Arid5b,Aida,Tnfsf4,Rnf19b |
| 8.164e-05 | -9.41 | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_DN | MSigDB lists | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_DN | 179 | 30 | 15632 | 1249 |
Arl4a,Kdm4a,Gbp2,Mark2,Sgk3,Sgcb,P2ry13,Gpsm2,Ttc39c,Gsr,Mllt6,Glipr2,Ppp2r5a,Ikzf1,Spry2,Fcgr2b,Rcn1,Dnajb4,Casp7,Atp10a,Trafd1,Lrrc8c,Stard7,Hcls1,Clic4,Osbpl3,Fzd5,Lnpep,Oas2,Btg2 |
| 8.164e-05 | -9.41 | GSE557_WT_VS_CIITA_KO_DC_DN | MSigDB lists | GSE557_WT_VS_CIITA_KO_DC_DN | 179 | 30 | 15632 | 1249 |
Ccl22,Tmem176b,Cdkn2d,Pml,Hvcn1,Arid5a,Arhgef3,Gramd1a,Dync1h1,Glipr2,Hspa2,Dusp8,Aida,Trib1,Ripk2,Dusp5,Pkp4,Ppp2r2a,Dnajb2,Lrrc8c,Plcl2,Col27a1,Asns,Dmwd,Plek,Jdp2,Sirt1,Stx11,Tmem176a,Slpi |
| 8.193e-05 | -9.41 | BROWNE_HCMV_INFECTION_6HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_6HR_UP | 62 | 15 | 15632 | 1249 |
Eif2ak2,Abcc5,Cnp,Irf7,Trim26,Pnp2,Oas1a,Ifnb1,Ch25h,Oasl1,Oas1g,Jmjd6,Isg15,Actb,Mark2 |
| 8.237e-05 | -9.40 | - | gene3d domains | 1.10.532.10 | 7 | 5 | 8819 | 755 |
Stat1,Stat3,Stat5a,Stat2,Stat4 |
| 8.237e-05 | -9.40 | - | gene3d domains | 2.60.40.630 | 7 | 5 | 8819 | 755 |
Stat1,Stat4,Stat2,Stat5a,Stat3 |
| 8.242e-05 | -9.40 | regulation of p38MAPK cascade | biological process | GO:1900744 | 42 | 11 | 20694 | 1406 |
Gadd45b,Il1b,Bmp2,Ezr,Dusp1,Met,Zc3h12a,Gadd45g,Sphk1,Hsph1,Phlpp1 |
| 8.303e-05 | -9.40 | GO_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | 69 | 16 | 15632 | 1249 |
H2-Q4,Fzd5,Traf2,H2-Q6,Cd40,Il6,Rsad2,Tnfsf4,H2-Q7,Malt1,Cd74,Il4ra,Nlrp3,Nr4a3,Clcf1,Tnfrsf14 |
| 8.319e-05 | -9.39 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP | 154 | 27 | 15632 | 1249 |
Ptgs2,Kcna3,Rcsd1,Socs3,Snn,Chd9,Junb,Map4k4,Maff,Rap1gap2,Isg20,Ddit4,Piezo1,Ubash3b,Kat2b,Irs2,Mxd1,Rnf139,Samhd1,Tnfaip3,Fos,Jun,Gadd45b,Parp8,Dusp1,Pik3r5,Ogfrl1 |
| 8.319e-05 | -9.39 | GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_UP | MSigDB lists | GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_UP | 154 | 27 | 15632 | 1249 |
Cnn3,Isg20,Sco1,Casp4,Pdk3,Nfil3,Cmpk2,Glrx,Cxcl1,Tnip3,Phf6,Spata5l1,Slc25a22,Dnaja2,Stat3,Stap1,Dbnl,Tcf4,Dock4,Rhbdf2,Src,Rnf114,Prpf38a,Rras2,Slc25a25,Pgs1,Prrg4 |
| 8.360e-05 | -9.39 | regulation of cell projection organization | biological process | GO:0031344 | 779 | 81 | 20694 | 1406 |
Nck1,Evl,Ust,Cdc42ep4,Met,Ezr,Rab21,Sdc2,Katna1,Fcgr2b,Mecp2,Mov10,Cenpj,Kif3c,P2ry12,Ehd1,Fzd1,Zswim4,Cx3cl1,Pdpn,P2ry2,Myo10,Fscn1,Rab3ip,Mark2,Ptk2,Dync1i2,Prag1,Agrn,Nlgn2,D16Ertd472e,Ifrd1,Igf1r,Stap1,Sipa1l1,Homer1,Sema4c,Tmem67,Rhoq,Spry2,Carmil1,Kat2b,Lrp8,Icam1,Rapgef2,Map4k4,Plk2,Cd38,Sema3c,Nr3c1,Prnp,Cdc42ep2,Src,Hap1,Lcn2,Sema4a,Eif4g2,Map2k1,Cyfip1,Il6,Scn1b,Lif,Mul1,Lpar1,Syne2,Lrp4,Cflar,Mdm2,Sirt1,Il15ra,Gfi1,Scarf1,Sphk1,Rap1gap2,Dbnl,Crkl,Itpr1,Lyn,Cav1,Kremen1,Cdk5r1 |
| 8.361e-05 | -9.39 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | MSigDB lists | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | 11 | 6 | 15632 | 1249 |
Traf2,Casp8,Fas,Tnf,Cflar,Tnfsf10 |
| 8.361e-05 | -9.39 | GO_REGULATION_OF_CHRONIC_INFLAMMATORY_RESPONSE | MSigDB lists | GO_REGULATION_OF_CHRONIC_INFLAMMATORY_RESPONSE | 11 | 6 | 15632 | 1249 |
Cx3cr1,Tnf,Ccl5,Adora2b,Il10,Tnfaip3 |
| 8.361e-05 | -9.39 | BIOCARTA_EPONFKB_PATHWAY | MSigDB lists | BIOCARTA_EPONFKB_PATHWAY | 11 | 6 | 15632 | 1249 |
Hif1a,Sod2,Nfkb1,Nfkbia,Cdkn1a,Jak2 |
| 8.361e-05 | -9.39 | BIOCARTA_D4GDI_PATHWAY | MSigDB lists | BIOCARTA_D4GDI_PATHWAY | 11 | 6 | 15632 | 1249 |
Casp1,Casp8,Jun,Cycs,Casp3,Apaf1 |
| 8.361e-05 | -9.39 | GO_POSITIVE_REGULATION_OF_MACROPHAGE_CHEMOTAXIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_MACROPHAGE_CHEMOTAXIS | 11 | 6 | 15632 | 1249 |
Thbs1,Csf1,Cmklr1,Ccl12,Ccl5,Cx3cl1 |
| 8.361e-05 | -9.39 | MODULE_377 | MSigDB lists | MODULE_377 | 11 | 6 | 15632 | 1249 |
Nat2,Alas1,Hk2,Eno2,Ldha,Eno1 |
| 8.361e-05 | -9.39 | GO_REGULATION_OF_FEVER_GENERATION | MSigDB lists | GO_REGULATION_OF_FEVER_GENERATION | 11 | 6 | 15632 | 1249 |
Ccl5,Ednrb,Tnf,Pla2g4a,Il1b,Ptgs2 |
| 8.361e-05 | -9.39 | HASEGAWA_TUMORIGENESIS_BY_RET_C634R | MSigDB lists | HASEGAWA_TUMORIGENESIS_BY_RET_C634R | 11 | 6 | 15632 | 1249 |
Usp18,Irf7,Ifit1bl1,Ifit1bl2,Dusp4,Dhx58 |
| 8.361e-05 | -9.39 | GO_NEGATIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | 11 | 6 | 15632 | 1249 |
Cd34,Tspo,Atp2b4,Zc3h12a,Il10,Cav1 |
| 8.427e-05 | -9.38 | Polymerase_NTP_transf_dom | interpro domains | IPR002934 | 12 | 6 | 19984 | 1430 |
Oas1a,Tent4a,Oas1g,Oas2,Tut7,Oas3 |
| 8.427e-05 | -9.38 | WWE-dom | interpro domains | IPR004170 | 12 | 6 | 19984 | 1430 |
Zc3hav1,Parp12,Tiparp,Parp14,Parp11,Dtx2 |
| 8.440e-05 | -9.38 | STAT_int | smart domains | SM00964 | 7 | 5 | 9567 | 823 |
Stat5a,Stat3,Stat4,Stat2,Stat1 |
| 8.481e-05 | -9.38 | bZIP | interpro domains | IPR004827 | 54 | 13 | 19984 | 1430 |
Maff,Cebpd,Fos,Jdp2,Atf3,Mafg,Mafk,Fosb,Nfil3,Jun,Junb,Batf2,Batf |
| 8.525e-05 | -9.37 | positive regulation of cytosolic calcium ion concentration | biological process | GO:0007204 | 302 | 39 | 20694 | 1406 |
Cav1,Cxcl3,Cxcl2,Gpr18,Jak2,Edn1,Ccrl2,Itgav,Htr2b,Itpr1,Gja1,Il1b,Ccr3,Ptgir,Htr2a,Ednrb,Swap70,Fpr1,Lpar1,Cacna1d,Cxcl1,Cx3cl1,Gna15,Ccl3,P2ry2,Ero1l,Ptger4,Kdr,Cmklr1,Cxcl10,Hap1,Fpr2,Cx3cr1,Ccr1,Xcr1,Cd38,Cacnb3,Adrb2,Gpr35 |
| 8.533e-05 | -9.37 | GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY_SEQUENCE_SPECIFIC_DNA_BINDING | MSigDB lists | GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY_SEQUENCE_SPECIFIC_DNA_BINDING | 595 | 74 | 15632 | 1249 |
Myc,Irf4,Nr4a1,Jun,Hmga1,Ets2,Spic,Fos,Hinfp,Ahr,Foxp4,Ifi207,Egr1,Atf3,Ifi214,Nr1h3,Plagl1,Etv3,Plscr1,Ifi211,Zeb1,Etv6,Ifi203,Pou2f2,Zscan29,Jdp2,Nfkb1,Dach1,Mndal,Irf8,Rel,Gfi1,Nfil3,Stat1,Max,Mafg,Irf1,Ifi204,Batf2,Egr2,Stat3,Nr3c1,Cebpd,Mafk,Aebp2,Ifi213,Ifi205,Tcf4,Bcl6,Ifi209,Tal2,Pbx1,Batf,Plagl2,Relb,Etv5,Csrnp1,Mxd1,Irf2,Prdm1,Hhex,Zfp281,Hif1a,Ifi208,Btg2,Maff,Jarid2,Junb,Irf7,Fosb,Nfkb2,Nfxl1,Nr4a3,Arid5b |
| 8.553e-05 | -9.37 | KIM_LIVER_CANCER_POOR_SURVIVAL_UP | MSigDB lists | KIM_LIVER_CANCER_POOR_SURVIVAL_UP | 20 | 8 | 15632 | 1249 |
Sphk1,Plod2,Tspan3,Etv5,Rgs1,Ctsc,Ddit4,Pfkfb3 |
| 8.553e-05 | -9.37 | REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION | MSigDB lists | REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION | 20 | 8 | 15632 | 1249 |
Ddx58,Traf2,Ifih1,Rnf135,Nfkbia,Ikbkg,Nfkbib,Nfkb2 |
| 8.565e-05 | -9.37 | GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN | MSigDB lists | GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN | 188 | 31 | 15632 | 1249 |
Usp18,Pigv,Hlx,Rgs3,Crlf3,Rbm43,Bmp2,Cdc42ep2,Ifit1bl1,Casp1,Nfkbie,Rsad2,Abcb1a,Slc44a1,Igsf6,Stap1,Spire1,Nr4a3,Ptprj,Ptk2,Mmp9,Filip1l,Plaur,Jak2,Chd9,Ralgds,Lcp2,Pik3r6,Map2k1,Ifit1bl2,Oas2 |
| 8.565e-05 | -9.37 | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN | MSigDB lists | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN | 188 | 31 | 15632 | 1249 |
Pnp2,Acvrl1,Bcl2a1d,Ifit1bl1,Bcl2a1b,Msr1,Psmb9,Ptpn2,Plau,Herc3,Rras2,Gbp2,Irak3,Irf2,Cd74,Ube2l6,Sap30,Procr,Timeless,Slc4a7,Ifit1bl2,Bcl2a1a,Il1rn,Rgs1,Cldnd1,Tax1bp1,Sp110,Il13ra1,Irf1,Tlr2,Acsl1 |
| 8.565e-05 | -9.37 | GSE27786_BCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_BCELL_VS_NKCELL_DN | 188 | 31 | 15632 | 1249 |
Dse,Nlrc5,Gsdmd,Acvr1,Errfi1,Slc15a3,Gbp9,Gbp4,Spry2,Slco3a1,Agtrap,Rtp4,Nck1,Chmp4b,Tnfrsf14,Ccdc88b,Hsd17b12,Stx6,Tbc1d13,Plscr1,Inpp5b,Nsmaf,Frmd4a,Smc5,Ptgir,Ebi3,Tnip1,Inpp1,Jak2,Cmklr1,Acsl5 |
| 8.580e-05 | -9.36 | GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN | MSigDB lists | GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN | 171 | 29 | 15632 | 1249 |
Ikzf1,Ggct,Irf4,Ccng2,Hivep2,Arhgef3,Eno1,Sla,Slc28a2,Evl,Egr1,Sdc1,Hif1a,Ext1,Phlda1,Rapgef2,Egln3,Rasgrp1,Jarid2,Sesn3,Nfkb1,Pdgfrb,Casp8,Jak2,Cd82,Adam19,Nfil3,Uaca,Dnajb4 |
| 8.580e-05 | -9.36 | GSE22886_IGA_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE22886_IGA_VS_IGM_MEMORY_BCELL_DN | 171 | 29 | 15632 | 1249 |
Btg2,4930523C07Rik,Plek,Plekha2,Fzd5,Plekha4,Tor1aip1,Jak2,Notch2,Snn,H3f3b,Hmox1,Dusp5,Zc3h12a,Map3k8,Rcn1,Il6,Dusp2,Fcgr2b,C1ra,Fgl2,Syk,Eif2ak2,Tcf4,Gpr18,Sla,Gng11,Dnase1l3,Kmo |
| 8.580e-05 | -9.36 | GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP | 171 | 29 | 15632 | 1249 |
P2ry14,Pikfyve,Trim13,Cd74,Aim2,Ddx60,Evl,Hck,Myd88,Slc25a37,Parp8,Rab11fip1,Traf3ip2,Rcl1,Rap2c,Prkx,Chd9,Dek,Sik3,Daam1,Hopx,Snx10,Jarid2,Parp12,Tdrd7,Tbc1d13,Dgka,H2-Aa,St3gal5 |
| 8.580e-05 | -9.36 | GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_UP | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_UP | 171 | 29 | 15632 | 1249 |
Pde1b,Phgdh,Cdyl2,Nlrc5,Ehd1,Zyx,Batf,Mvp,Tap1,Mdfic,Tle3,Atp2b4,Nek6,Fas,Ppm1l,Slc7a5,Jdp2,Tuba4a,Hk1,Casp8,Itgal,Cd86,Daam1,Cflar,Keap1,Ppfibp2,Hmox1,Rnf19b,Ebi3 |
| 8.594e-05 | -9.36 | negative regulation of neuron apoptotic process | biological process | GO:0043524 | 180 | 27 | 20694 | 1406 |
Map2k4,Ccl12,Cx3cr1,Angpt1,Cpeb4,Hsph1,Hdac1,Mt1,Adora2a,Cx3cl1,Sod2,Jun,Hif1a,Kdr,Stxbp1,Nes,Mecp2,Gclc,Axl,Sirt1,Gclm,Optn,Btg2,Hmox1,Clcf1,Nr4a3,Jak2 |
| 8.607e-05 | -9.36 | skeletal muscle tissue development | biological process | GO:0007519 | 142 | 23 | 20694 | 1406 |
Atf3,Rcan1,Nr4a1,Hivep3,Notch1,Btg2,Myc,Met,Bcl9,Hlx,Cav1,Fos,Cflar,Sap30,Psma6,Nupr1,Maff,Egr1,Plagl1,Cited2,Flnb,Egr2,Homer1 |
| 8.614e-05 | -9.36 | zf-B_box | pfam domains | PF00643 | 61 | 14 | 18711 | 1348 |
Mid1,Trim21,Trim12a,Trim26,Trim36,Trim14,Trim13,Trim34a,Trim12c,Pml,Trim56,Trim30a,Trim30d,Mefv |
| 8.635e-05 | -9.36 | GO_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | 91 | 19 | 15632 | 1249 |
Smpdl3b,Ptpn2,Il10,Tnfrsf1b,Nfkb1,Spn,Cx3cr1,Rabgef1,Tnfaip3,Mefv,Nr1h3,Nlrp3,Adrb2,Il12b,Calcrl,Socs3,Zc3h12a,Abr,Ptger4 |
| 8.675e-05 | -9.35 | modulation of growth of symbiont involved in interaction with host | biological process | GO:0044144 | 23 | 8 | 20694 | 1406 |
Tnf,Il12b,Tlr2,Irf8,Nod2,Il10,Myd88,Sqstm1 |
| 8.748e-05 | -9.34 | NTP_transf_2 | pfam domains | PF01909 | 12 | 6 | 18711 | 1348 |
Oas1a,Oas3,Tent4a,Oas1g,Tut7,Oas2 |
| 8.756e-05 | -9.34 | dephosphorylation | biological process | GO:0016311 | 240 | 33 | 20694 | 1406 |
Phlpp1,Nck1,Dusp5,Acpp,Dusp2,Ppp2r2a,Ppp1r15b,Ptprj,Eya4,Ubash3b,Plpp3,Dusp1,Inpp1,Phlpp2,Dusp6,Ppm1k,Inpp5b,Minpp1,Dusp8,Dusp4,Acp5,Ptpn2,Ppp1r15a,Mtmr14,Dusp28,Ppp4r2,Ppp2r3a,Acp2,Dusp14,Dusp16,Plpp1,Ppp2r5a,Ppm1l |
| 8.764e-05 | -9.34 | MORI_IMMATURE_B_LYMPHOCYTE_UP | MSigDB lists | MORI_IMMATURE_B_LYMPHOCYTE_UP | 49 | 13 | 15632 | 1249 |
Cd83,Samhd1,Hck,Pml,Lyn,Cd74,Rhoq,Tapbp,Dusp6,Birc3,Jarid2,Cd40,Rgs14 |
| 8.764e-05 | -9.34 | PID_CASPASE_PATHWAY | MSigDB lists | PID_CASPASE_PATHWAY | 49 | 13 | 15632 | 1249 |
Apaf1,Casp7,Ptk2,Casp2,Cycs,Casp3,Traf2,Birc2,Casp4,Casp8,Tnf,Birc3,Casp1 |
| 8.893e-05 | -9.33 | tissue morphogenesis | biological process | GO:0048729 | 627 | 68 | 20694 | 1406 |
Jag1,Vasp,Mthfr,Flt1,Hif1a,Il6,Pdgfb,Bmp2,Src,Nrp2,Sema3c,Timeless,Lhx2,Nr3c1,Ahr,Pbx1,Nr4a3,Inhba,Gja1,Lmo4,Ptch1,Flrt3,Casp3,Spint2,Hmga2,Hhex,Notch1,Txnrd1,Mthfd1l,Mdm2,Pdpn,Fzd1,Stat5a,Kdr,Socs3,Tnc,Cited2,Vegfc,Phactr4,Tulp3,Intu,Acvr1,Sdc4,Pml,Il10,Casp8,Acvrl1,Angpt1,Met,Ift57,Apaf1,Csf1,Spry2,Notch2,Edn1,Tmem67,Sema4c,Clic4,Igf1r,Prkx,Kdm6b,Kdm5b,Mmp14,Fzd5,Rpgrip1l,Plod3,Myc,Sec24b |
| 8.903e-05 | -9.33 | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN | 197 | 32 | 15632 | 1249 |
Piezo1,Abtb2,Hdc,Atp6v1d,Cnp,Tnfsf10,Cflar,Acsl5,Keap1,Gfi1,Sp110,Stard7,Etnk1,Map2k4,Trib1,Tgfbi,Rab11fip1,Stap1,Ppp2r5a,Casp3,Gclm,Cox17,H2-Q4,H2-Q6,Batf,Cd38,H2-Q7,Tmem176b,Traf1,Tpx2,Pttg1,Ccl22 |
| 8.923e-05 | -9.32 | cellular response to growth factor stimulus | biological process | GO:0071363 | 422 | 50 | 20694 | 1406 |
Sphk1,Crkl,Flrt3,Casp3,Cav1,Nfkb1,Prkce,Sirt1,Mapkapk2,Notch1,Il6,Pdgfb,Flt1,Acvr1b,Fos,Rapgef2,Nrp2,Nr3c1,Egr3,Src,Gcnt2,Hap1,Bmp2,Igf1r,Fut8,Spry2,Serpine1,Flrt2,Egr1,Gdf15,Pdgfrb,Dcp1a,Zfp36,Ptk2,Vegfc,Cited2,Bambi,Kdr,Jun,Ehd1,Apaf1,Acvrl1,Col4a2,Ccl2,Zyx,Il10,Pml,Acvr1,Ddit4,Nr4a1 |
| 8.960e-05 | -9.32 | positive regulation of lipid localization | biological process | GO:1905954 | 89 | 17 | 20694 | 1406 |
Msr1,Edn1,Ptch1,Hilpda,Ehd1,Ikbke,Il1a,P2ry2,Lipg,Nfkbia,Zc3h12a,Sirt1,Fabp3,C3,Acsl5,Il1b,Nr1h3 |
| 8.971e-05 | -9.32 | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN | MSigDB lists | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN | 163 | 28 | 15632 | 1249 |
Atf3,Gpr141,Agtrap,Gng11,Slc25a25,Rnd3,Tagln,Ifit1bl1,Dse,Pde5a,Dusp5,Il18,Lox,Ifit3b,Rcan1,Bambi,Thbs1,Gbp2b,Serpinb2,Pf4,Dusp6,Ifit1bl2,Ifit3,Myo1b,Ppp2r3a,Tdrd7,Usp12,Vasn |
| 8.971e-05 | -9.32 | GSE25846_IL10_POS_VS_NEG_CD8_TCELL_DAY7_POST_CORONAVIRUS_BRAIN_UP | MSigDB lists | GSE25846_IL10_POS_VS_NEG_CD8_TCELL_DAY7_POST_CORONAVIRUS_BRAIN_UP | 163 | 28 | 15632 | 1249 |
Tpi1,Atf3,Bmp2,Cd83,Tnfaip3,Usp53,Sod2,Bcl2a1b,Spn,Nfkbia,Homer1,Abcb1a,Bcl2a1d,Optn,Ldha,Filip1l,C3,Egr3,Clec5a,Ccl4,Bambi,Bcl2a1a,Cxcl1,Il1b,Rrs1,Adap2,Osm,Inhba |
| 9.064e-05 | -9.31 | GSE7460_CD8_TCELL_VS_TREG_ACT_UP | MSigDB lists | GSE7460_CD8_TCELL_VS_TREG_ACT_UP | 180 | 30 | 15632 | 1249 |
Notch1,Atp2b4,Herc3,Bfar,St3gal6,Malt1,Evl,Arhgap26,Ikzf1,Abcb1a,P2ry13,Gpr18,Dse,Itpr1,Acpp,Bcl2l11,Trafd1,Plaur,Agpat4,Dio2,Epsti1,Ccl4,Il1rn,Gtpbp2,Clcf1,Nsmaf,Mppe1,Bcorl1,Dmwd,Pde4b |
| 9.064e-05 | -9.31 | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN | MSigDB lists | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN | 180 | 30 | 15632 | 1249 |
Rcsd1,Mefv,Ptger4,Abcc4,Idi1,Osbpl3,Il1rn,Notch2,Serpine1,Gch1,Stx11,Slc39a14,Vasn,Car13,Degs2,Procr,Inpp5b,Dtwd1,Ciapin1,Tmtc2,Nfkbiz,Dusp14,Ppfibp1,Tal2,Gnb4,Fam43a,Nr4a1,Cpd,Dusp4,Fut8 |
| 9.064e-05 | -9.31 | GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_DN | MSigDB lists | GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_DN | 180 | 30 | 15632 | 1249 |
Errfi1,Slc44a1,Zyx,Gadd45b,Mark2,Crim1,Pbx1,Rbm43,Hinfp,Arl4a,Isg15,Usp25,Pgs1,Rasgrp1,Rictor,Rab10,Ociad1,Bcl9,Gem,Cd86,Mov10,Tshz1,Sesn3,Brd2,Nampt,Dusp16,Tmem123,Tax1bp1,Acvr1b,Smc5 |
| 9.246e-05 | -9.29 | GO_INNATE_IMMUNE_RESPONSE_ACTIVATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_INNATE_IMMUNE_RESPONSE_ACTIVATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | 99 | 20 | 15632 | 1249 |
Relb,Clec4e,Tab2,Clec4d,Lyn,Psmb10,Psme1,Malt1,Psmb6,Psma6,Psme2,Psmd10,Psmb9,Psmb8,Nfkbia,Clec4n,Src,Syk,Nfkb1,Ikbkg |
| 9.246e-05 | -9.29 | GO_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | MSigDB lists | GO_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 99 | 20 | 15632 | 1249 |
Prdx5,Nqo1,Il18rap,Il18bp,Sirt1,Mdm2,Il6,Bnip3,Klf2,Fos,Traf2,Sod2,Klf6,Src,Tnfaip3,Prdx1,Sphk1,Hif1a,Kdm6b,Fas |
| 9.322e-05 | -9.28 | GSE37301_PRO_BCELL_VS_CD4_TCELL_UP | MSigDB lists | GSE37301_PRO_BCELL_VS_CD4_TCELL_UP | 155 | 27 | 15632 | 1249 |
Ikbke,Tnip1,Sp110,Pkp4,Dck,Endod1,Ptger4,Sema4a,Rnf145,Wdr59,Hivep3,Sesn3,Jarid2,Cd83,Rbl1,Tlr6,Plagl1,Cyth3,Tnfsf8,Stard5,Mllt6,Ifit2,Parp8,Spsb1,Tcf4,Arhgef3,Arid5a |
| 9.322e-05 | -9.28 | GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | 155 | 27 | 15632 | 1249 |
Plod2,Asah2,Map4k4,Arid4a,Etv6,Rictor,Noc4l,Tifa,Cd200,Fndc3a,Ptger4,Prkar2b,Igf1r,Acsl5,Tcf4,Itpr1,Klf3,Parp8,Ift57,Dock10,Kdm5b,Nr3c1,Gbe1,Calcrl,Tmem176b,Aim2,Pnpt1 |
| 9.457e-05 | -9.27 | adherens junction | cellular component | GO:0005912 | 293 | 38 | 20747 | 1409 |
Pkp4,Irf2,Nectin4,Frmd4a,Itgav,Vasp,Evl,Mpp7,Flnb,Ezr,Map2k1,Zyx,Dst,Ptk2,Itga5,Pdlim7,Keap1,Nectin2,Gja1,Asap3,Itgb8,Notch1,Rnd1,Lyn,Sdc4,Map4k4,Syne2,Cav1,Prag1,Flrt3,Hck,Flrt2,Cdc42ep4,Tnks1bp1,Jak2,Jag1,Pvr,Cyth3 |
| 9.472e-05 | -9.26 | calcium ion homeostasis | biological process | GO:0055074 | 479 | 55 | 20694 | 1406 |
Ccr3,Ptgir,Bnip3,Htr2a,Ednrb,Fpr1,Cxcl2,Ccl5,Cd40,Atp13a1,Ccrl2,Edn1,Cx3cr1,Ccr1,Pml,Adrb2,Slc30a1,Gpr35,Ccl2,Cacna1d,Cxcl1,Cx3cl1,Ccl3,P2ry2,Ptger4,Atp2b4,Kdr,Cmklr1,Grina,Il1b,Tmtc2,Swap70,Cav1,Cxcl3,Gpr18,Prkce,Marcksl1,Jak2,Gja1,Htr2b,Itgav,Itpr1,Hap1,Fpr2,Snx10,Xcr1,Cd38,Cacnb3,Lpar1,Rmdn3,Gna15,Ero1l,1600014C10Rik,Tmem178,Cxcl10 |
| 9.478e-05 | -9.26 | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP | 189 | 31 | 15632 | 1249 |
Layn,Dmwd,Casp2,Nr4a3,Clec4d,Pkp4,Igf2bp2,Esd,Lrrc8c,Frmd6,Bambi,Homer1,Tspan3,Ttc39c,Arid5a,Trip10,Cd40,Spryd7,Chst11,S1pr2,Ncoa5,Atp13a1,Rab19,Prnp,Sphk1,Mcoln2,Clcn5,Plau,Bmp2,Ahsa1,Gpc1 |
| 9.478e-05 | -9.26 | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN | 189 | 31 | 15632 | 1249 |
Ube2e1,Irf2,Tlr6,Pdgfc,Hvcn1,Rhoc,Ahr,Src,Arhgap26,Ap3b1,Gsr,B3gnt5,Cebpd,Mthfd2,Map3k8,Rtn1,Dusp5,Cdkn1a,Nfil3,Notch2,Jak2,Actb,Rel,Lap3,Nampt,Slc31a2,Rhou,Sap30,Srxn1,Rab10,Plscr1 |
| 9.478e-05 | -9.26 | GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_DN | MSigDB lists | GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_DN | 189 | 31 | 15632 | 1249 |
Palld,P2ry14,Traf1,Col4a2,Chmp4b,Angpt1,Samhd1,Dusp1,Zyx,Slfn8,Ifi44,Myc,Optn,Chst11,Kdm5b,Smox,Ms4a6d,Serpinb9,Ikbke,Slfn9,Abcc1,Abcc4,Nlgn2,Eno2,Dach1,Dmwd,Wdfy1,Bcorl1,Xaf1,Tmem176a,Spint2 |
| 9.548e-05 | -9.26 | - | gene3d domains | 2.60.40.10 | 736 | 92 | 8819 | 755 |
Nectin4,Met,Fcgr4,Il12b,Tapbp,Nectin2,Sema4a,Flt1,Pilrb1,Sema4c,Gbe1,F11r,Fndc3a,Tnc,Sema3c,B430306N03Rik,H2-M2,Igsf6,Cd274,Cd200,A530064D06Rik,Vasn,Cd83,Pilra,Tapbpl,Pilrb2,Ebi3,Cd86,Kdr,Ifnar1,Milr1,Icam1,Fcgr2b,H2-Q6,Arel1,Csf3r,Trim36,Vcan,H2-Ab1,Igf1r,H2-Eb1,Malt1,C3,Scn1b,H2-Q4,Cd300lf,Siglece,Il18rap,Vcam1,H2-T22,Cd80,H2-Aa,Il4ra,Mfap3l,Cd300e,Slamf9,Relb,Igsf9,Il2rg,Inpp5b,Clmp,Slamf8,Palld,Ptprj,Il18bp,Pvr,Slamf7,Treml2,Igsf8,Pdgfrb,Fcgr1,Icosl,Rel,Nfkb1,Il13ra1,Flrt2,Crlf3,Lrp11,H2-Q7,Trem1,Nfkb2,Nxpe3,Flnb,Treml4,Axl,Cd200r4,Gm5150,H2-T24,H2-T10,Il12rb1,Mid1,Tarm1 |
| 9.549e-05 | -9.26 | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_DN | MSigDB lists | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_DN | 172 | 29 | 15632 | 1249 |
Ahsa1,Pgm1,Socs1,Pgs1,Mcoln2,Lrp8,Tra2a,Mdn1,Cish,Gbp4,Gbp9,Slc2a1,Srm,Usp53,Pik3r5,Pfkl,Pkp4,Fam162a,Wdr43,Abcc1,Odc1,Mthfd2,Usp31,Ldha,Socs3,Slc39a14,Syne2,Rasgrp1,Hk2 |
| 9.549e-05 | -9.26 | GSE360_DC_VS_MAC_T_GONDII_UP | MSigDB lists | GSE360_DC_VS_MAC_T_GONDII_UP | 172 | 29 | 15632 | 1249 |
Etv6,Ppp2r3a,Spint2,Nmi,H2-Aa,Psme2,Nrp2,Inpp5b,Hdc,Hopx,Txn1,Gfi1,Tnfaip2,Adam19,Fscn1,Nr4a3,Trib1,Dusp5,Tlk2,Ly75,Ccl2,Ctsc,Dnase1l3,Pbx1,Cd83,Traf5,Socs1,Il1a,Palld |
| 9.550e-05 | -9.26 | MODULE_522 | MSigDB lists | MODULE_522 | 31 | 10 | 15632 | 1249 |
Trip10,Ptpn2,Denr,Txn1,Spsb1,Hlx,Gramd1a,Relb,Il15ra,Nfkb2 |
| 9.551e-05 | -9.26 | GO_TUBE_DEVELOPMENT | MSigDB lists | GO_TUBE_DEVELOPMENT | 537 | 68 | 15632 | 1249 |
Sdc4,Sdc1,Myc,Pdpn,Mmp14,Spry2,Edn1,Ift57,Phactr4,Ass1,Bcl2l11,Cited2,Rpgrip1l,Cdkn1a,Lhx2,Stat1,Sema4c,Timeless,Zeb1,Csf1,Met,Jag1,Ednrb,Lmo4,Ptch1,Sema3c,Pbx1,Bmp2,Sav1,Pdgfc,Apaf1,Notch1,Pml,Lif,Hhex,Hlx,Prdm1,Intu,Arg2,Jmjd6,Tulp3,Hif1a,Setdb2,Cp,Tnc,Phgdh,Acvrl1,Stk40,Acvr1,Kdm5b,Errfi1,Clmp,Plod3,Tnf,Src,Gpsm2,Clic4,Prkx,Sec24b,Nr4a3,Lox,Fzd1,Vasp,Gja1,Mthfd1l,Map2k1,Klf2,Hopx |
| 9.561e-05 | -9.26 | CHIBA_RESPONSE_TO_TSA | MSigDB lists | CHIBA_RESPONSE_TO_TSA | 43 | 12 | 15632 | 1249 |
Srxn1,Stx6,Optn,Sqstm1,Txnrd1,Dusp1,Sdc4,Prdx1,Cdkn1a,H3f3b,Stat1,Tpi1 |
| 9.561e-05 | -9.26 | PID_TCPTP_PATHWAY | MSigDB lists | PID_TCPTP_PATHWAY | 43 | 12 | 15632 | 1249 |
Stat1,Pik3cd,Kdr,Eif2ak2,Src,Stat5a,Pdgfrb,Ptpn2,Csf1,Pdgfb,Stat3,Met |
| 9.621e-05 | -9.25 | GO_RUFFLE | MSigDB lists | GO_RUFFLE | 147 | 26 | 15632 | 1249 |
Fscn1,Arf4,Mefv,Ptprj,Mtmr14,Itga5,Pdlim7,Samsn1,Layn,Plek,Myadm,Myo10,Cyth3,Spata13,Ddx58,Fgr,Asap3,Palld,Psd,Spry2,Pdpn,Dbnl,Cyfip1,Src,Ezr,Itgav |
| 9.621e-05 | -9.25 | GO_ENDOCYTIC_VESICLE_MEMBRANE | MSigDB lists | GO_ENDOCYTIC_VESICLE_MEMBRANE | 147 | 26 | 15632 | 1249 |
H2-Aa,Tlr1,Rab10,Inpp5b,Ptch1,Cav1,Fzd5,Marco,H2-Eb1,Ldlr,Tlr2,Rab20,H2-Ab1,Scarf1,Mdm2,Rab11fip1,Rab9,Irgm2,Msr1,H2-Q6,H2-Q4,Rab32,Fcgr1,Cd74,Tlr6,H2-Q7 |
| 9.824e-05 | -9.23 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION | 198 | 32 | 15632 | 1249 |
Psmb8,H2-Eb1,Lnpep,Tap2,Rab10,H2-Aa,Psme2,H2-Ab1,Psmb6,Kif3c,Sec24a,Sec24b,Rab32,H2-Q4,Dync1h1,Cenpe,Itgav,H2-Q6,Psmb9,Psmd10,Abcb1a,Ap3b1,Tapbp,Psma6,H2-Q7,Psme1,Icam1,Cd74,Psmb10,Fcgr1,Tap1,Relb |
| 9.824e-05 | -9.23 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_UP | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_UP | 198 | 32 | 15632 | 1249 |
Dusp5,Dnajb2,Nfil3,Agpat4,Rgs1,Sipa1l1,Il10,Junb,Stx11,Adora2a,Kctd12,Zeb1,Traf1,Plagl1,Hif1a,Tnfaip3,Rab3ip,Klf7,Serp1,Fos,Itgav,Lrp4,Spn,Gadd45b,Hspa2,Phlpp1,Ifrd1,Aebp2,Nfkbie,Ap3b1,Chst11,Mdn1 |
| 9.901e-05 | -9.22 | positive regulation of protein modification by small protein conjugation or removal | biological process | GO:1903322 | 134 | 22 | 20694 | 1406 |
Dcun1d3,Sphk1,Birc2,Nod2,Tnip1,Dnajb2,Mul1,Trib1,Cav1,Ripk2,Psmd10,Ahrr,Adrb2,Arrdc4,Fbxo4,Tank,Angpt1,Zc3h12a,Peli1,Birc3,Trib3,Nmi |
| 9.923e-05 | -9.22 | PID_FAS_PATHWAY | MSigDB lists | PID_FAS_PATHWAY | 37 | 11 | 15632 | 1249 |
Casp3,Birc2,Casp8,Ikbkg,Syk,Src,Birc3,Ezr,Cflar,Pik3cd,Fas |
| 9.923e-05 | -9.22 | GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS | 37 | 11 | 15632 | 1249 |
Zc3h12a,Dyrk2,Nfkbil1,Nfkbia,Nlrp3,Psmd10,Il10,Nfkbib,Keap1,G3bp2,Nfkbie |
| 9.923e-05 | -9.22 | PID_FRA_PATHWAY | MSigDB lists | PID_FRA_PATHWAY | 37 | 11 | 15632 | 1249 |
Jun,Lif,Hmox1,Gja1,Mmp9,Ccl12,Junb,Plaur,Ccnd1,Il6,Plau |
| 9.969e-05 | -9.21 | CORRE_MULTIPLE_MYELOMA_UP | MSigDB lists | CORRE_MULTIPLE_MYELOMA_UP | 63 | 15 | 15632 | 1249 |
Rnf145,Cd200,Tnfsf4,Il1b,Glrx,Serpinb2,Plat,Serpine1,Samsn1,Usp53,Gdf15,Fam43a,AA467197,Maff,Slc7a5 |
| 9.975e-05 | -9.21 | LINDVALL_IMMORTALIZED_BY_TERT_UP | MSigDB lists | LINDVALL_IMMORTALIZED_BY_TERT_UP | 70 | 16 | 15632 | 1249 |
Ext1,Peli1,Pde5a,Tapbp,Triobp,Tshz1,Usp53,Ass1,Arid5a,Cav1,Cited2,Hmga1,Mdfic,Uchl1,Frmd4a,Papss2 |
| 9.990e-05 | -9.21 | GSE9960_HEALTHY_VS_SEPSIS_PBMC_DN | MSigDB lists | GSE9960_HEALTHY_VS_SEPSIS_PBMC_DN | 131 | 24 | 15632 | 1249 |
Mndal,Plekha2,Ifi211,Ifi208,Zfp36,Ifi203,Ifi204,Notch2,Sec24b,Ifi213,Apobec3,Swap70,Ifi209,Ifi205,Prkce,Rsad2,Samd9l,Nupr1,Ifi214,Sass6,Rbm43,Ifi207,Aff1,Foxp4 |
| 1.000e-04 | -9.21 | mouse chr17 | chromosome location | mouse chr17 | 376 | 42 | 24173 | 1464 |
Cdkn1a,Hspa1a,Fpr1,H2-T10,H2-Ab1,H2-Q4,Hmga1,Clcn7,Ebi3,Brd2,H2-Q5,Psmb9,H2-Q7,Kat2b,Zfp40,Tnf,Tap2,H2-T24,H2-T22,Pim1,Sod2,Tapbp,C3,H2-Eb1,Nfkbil1,Hspa1b,H2-Q6,Tap1,H2-Aa,Lst1,BC051226,H2-K2,Trim26,Psmb8,H2-M2,Eif2ak2,Col11a2,Dusp1,Gm16712,Adgre4,Daxx,Rhoq |
| 1.001e-04 | -9.21 | ATF2_UP.V1_DN | MSigDB lists | ATF2_UP.V1_DN | 164 | 28 | 15632 | 1249 |
Pcx,Gsr,Rab11fip1,Pdpn,Kcnj2,Pla2g4a,Cd302,Arhgef3,Fos,Ccl12,Sod2,Aff1,Irs2,Kctd12,Spint2,Ppp4r2,C1rl,Pid1,Gch1,Trem1,Vcam1,Serpinb9,Pim1,Ptgs2,Ak4,Adora2b,Cd200,Zc3h12a |
| 1.001e-04 | -9.21 | GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_DN | 164 | 28 | 15632 | 1249 |
Chst11,Pnp2,Carhsp1,Insl6,Plac8,Phf11b,Irak3,Phf11c,Cd80,Phf11a,Gem,Samsn1,Hopx,Myadm,Snx10,Ttc9c,Glrx,Cdkn1a,Il1b,Idi1,Rgs1,Ttc39b,Serpinb9,Cxcl10,Phf11d,Ppa1,Dck,Dusp5 |
| 1.003e-04 | -9.21 | Signaling by SCF-KIT | REACTOME pathways | R-MMU-1433557 | 289 | 45 | 8608 | 757 |
Stat3,Met,Mdm2,Ptk2,Ier3,Psmb8,Psme2,Trib3,Cd80,Psma6,Stat1,Rapgef2,Rasgrp1,Psme1,Dusp5,Psmb6,Dusp6,Cdkn1a,Kitl,Pdgfb,Rictor,Ppp2r5a,Irs2,Ksr1,Il2rg,Pdgfrb,Mmp9,Cd86,Jak2,Map2k1,Psmb10,Psmd10,Phlpp1,Pik3cd,Stat5a,Psmb9,Spred1,Angpt1,Psme2b,Phlpp2,Lyn,Src,Socs1,Ppp2r1b,Nr4a1 |
| 1.004e-04 | -9.21 | regulation of MHC class I biosynthetic process | biological process | GO:0045343 | 5 | 4 | 20694 | 1406 |
Pml,Hsph1,Nlrc5,Ciita |
| 1.004e-04 | -9.21 | positive regulation of MHC class I biosynthetic process | biological process | GO:0045345 | 5 | 4 | 20694 | 1406 |
Pml,Nlrc5,Hsph1,Ciita |
| 1.004e-04 | -9.21 | negative regulation of toll-like receptor 2 signaling pathway | biological process | GO:0034136 | 5 | 4 | 20694 | 1406 |
Nod2,Lyn,Acod1,Tlr6 |
| 1.004e-04 | -9.21 | regulation of cellular response to macrophage colony-stimulating factor stimulus | biological process | GO:1903972 | 5 | 4 | 20694 | 1406 |
Tlr2,Csf1,Stap1,Ptpn2 |
| 1.004e-04 | -9.21 | regulation of natural killer cell chemotaxis | biological process | GO:2000501 | 5 | 4 | 20694 | 1406 |
Ccl5,Ccl4,Ccl12,Cxcl14 |
| 1.004e-04 | -9.21 | regulation of response to macrophage colony-stimulating factor | biological process | GO:1903969 | 5 | 4 | 20694 | 1406 |
Ptpn2,Stap1,Csf1,Tlr2 |
| 1.005e-04 | -9.21 | GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_DN | MSigDB lists | GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_DN | 181 | 30 | 15632 | 1249 |
Il1rn,Ccl4,Prkx,Nfil3,Gfi1,Ripk2,Itga9,Il18,Spen,Med13,Il18rap,Spint2,Ppp2r3a,Kctd12,Fcgr4,Lcp2,Flrt2,Il10,Sla,P2ry14,Il4ra,Sell,Socs1,Pla2g4a,Lrch1,Fgl2,Vcan,Bcl2l11,Mgat1,Gpsm2 |
| 1.005e-04 | -9.21 | GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_DN | MSigDB lists | GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_DN | 181 | 30 | 15632 | 1249 |
Casp4,Vezt,Ifit3,Nampt,Tifa,Ifit3b,Fndc3a,Ppa1,Scyl2,Gng4,Mob3c,Fscn1,Nfxl1,Ifnar1,Gypc,Casp1,Aoah,Ogfrl1,Ifih1,Rnf135,Isg15,Usp18,Hhex,Ifit1,Apaf1,Pdgfc,Fcgr1,Zbp1,Rbm43,Il15 |
| 1.005e-04 | -9.21 | GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_UP | MSigDB lists | GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_UP | 181 | 30 | 15632 | 1249 |
Bcl6,Jun,Timp1,B4galt4,Apobec3,Cpd,Nfkbie,Il6,Minpp1,Nr3c1,Traf1,Plagl1,Pttg1,Atf3,Mdfic,Pde3b,Cd83,Gem,Rel,Abtb2,Pde4b,Mmd,Flnb,Map2k4,Acsl1,Gpd2,Irf1,Ptk2,Cdkn1a,Jak2 |
| 1.008e-04 | -9.20 | negative regulation of reactive oxygen species biosynthetic process | biological process | GO:1903427 | 36 | 10 | 20694 | 1406 |
Zc3h12a,Sirt1,Stat3,Acp5,Atp2b4,Cd34,Cav1,Tspo,Cflar,Il10 |
| 1.011e-04 | -9.20 | defense response to Gram-positive bacterium | biological process | GO:0050830 | 116 | 20 | 20694 | 1406 |
Gbp2,Gsdmd,Acp5,Hck,Myd88,Gbp3,Tnfsf8,Nlrp3,Fgr,Gbp8,Klrk1,Gbp7,Gbp9,Gbp2b,Ripk2,Tnfrsf14,Nod2,Nod1,Tnf,Tlr2 |
| 1.019e-04 | -9.19 | focal adhesion | cellular component | GO:0005925 | 153 | 24 | 20747 | 1409 |
Jak2,Flrt2,Hck,Flrt3,Prag1,Sdc4,Cav1,Map4k4,Syne2,Itgb8,Asap3,Ptk2,Dst,Keap1,Pdlim7,Itga5,Map2k1,Zyx,Ezr,Flnb,Evl,Vasp,Itgav,Irf2 |
| 1.025e-04 | -9.19 | protein secretion | biological process | GO:0009306 | 153 | 24 | 20694 | 1406 |
Itgav,Lcp2,Stxbp3,Tlr6,Nlrc4,Rab10,Tlr2,Notch2,Lyn,Nod2,Svbp,Optn,Pou2f2,Traf3ip2,Il1rn,Isg15,Notch1,Nlrp3,Rnf19b,Mcoln2,Aim2,Nos2,Plek,Trem1 |
| 1.034e-04 | -9.18 | Costimulation by the CD28 family | REACTOME pathways | R-MMU-388841 | 58 | 15 | 8608 | 757 |
Cd80,Ppp2r5a,Trib3,Lyn,Src,Icosl,H2-Aa,Rictor,H2-Eb1,Map3k8,H2-Ab1,Cd274,Tnfrsf14,Cd86,Ppp2r1b |
| 1.040e-04 | -9.17 | regulation of natural killer cell activation | biological process | GO:0032814 | 43 | 11 | 20694 | 1406 |
Il15ra,Lgals9,Stat5a,Axl,Il12b,Rasgrp1,Il15,Prdm1,Slamf7,Il18,Irf1 |
| 1.041e-04 | -9.17 | TGGAAA_NFAT_Q4_01 | MSigDB lists | TGGAAA_NFAT_Q4_01 | 1680 | 175 | 15632 | 1249 |
Atxn7l1,Syne2,Usp12,Tnfrsf1b,Lmo4,Pid1,Ppp2r1b,Col27a1,Pim2,Cpeb4,Cacnb3,Mmp14,S1pr2,Psip1,Gadd45b,Cited2,Zbtb5,Sdc4,Spred1,Klf7,Tpi1,Usp25,Bcor,Ubash3b,Ext1,Ppp2r3a,Snx2,Hsd17b12,Gcnt2,Ptges,Pkp4,Stip1,Map3k8,Nr4a3,Ntng2,Stat3,Aebp2,Mecp2,Phldb1,Slc25a37,Tcf4,Homer1,Plagl2,Olfml3,Gda,Prdm1,Tab2,Akt3,Jag1,Rnf19a,Ltbp2,Mier3,Ptch1,Rgs1,Dr1,Gfi1,Agpat4,Tagap,Ier3,Irf4,Kcnj2,Chst11,Tra2a,Flrt3,Dock4,Fos,Znfx1,Rbms2,Angpt1,Tnks1bp1,Atp2b4,Pgs1,Abr,Arrdc4,Pdgfb,Arid4a,Jarid2,Daam1,Ppm1k,Vegfc,Lox,Cxcl10,Egr2,Cish,Zfp800,N4bp1,Gypc,Hsph1,Src,Gpsm2,Itpr1,Tnfrsf8,Mdfic,Lif,Isg15,Calcrl,Hif1a,Med13,Ppp4r2,Jdp2,Dcun1d3,S100a8,Lap3,Plod2,Rap2c,Ccl4,Cd82,Nfil3,Cdkn1a,Sema4c,Katna1,Rin2,Vcan,Nr4a1,Dnaja1,D16Ertd472e,Ets2,Slc16a1,Extl2,Stxbp1,Irs2,Tmeff1,Inhba,Slc25a12,Ccl5,Pde4b,Nfkb2,Il2rg,Gpr85,Rcan1,Phf6,Itgb8,Phgdh,Errfi1,Tnf,Armcx6,Bcl6,Sla,Etv5,Rab3ip,Rgs3,Klf8,Cd74,Bcl9,Pdk3,C1rl,Sh3bgrl2,Plekhn1,Il6,Spry2,Ccl12,Nfkbia,Pde3b,Ppfibp1,Tmtc2,Antxr1,Maff,Dgka,Wars,Nfkbid,Map4k4,Slc7a8,Cd86,Tnfsf10,Il1rn,Dio2,Uchl1,Il12b,Pim1,Pde1b,Nr3c1,Bmp2,Apba1,Ube2e1,Icam1 |
| 1.059e-04 | -9.15 | GO_IDENTICAL_PROTEIN_BINDING | MSigDB lists | GO_IDENTICAL_PROTEIN_BINDING | 1122 | 124 | 15632 | 1249 |
Pdgfc,Apaf1,Irak3,Myd88,Slc39a13,Cd74,Aim2,Glipr2,Stat3,Traf2,Tcf4,Ifi209,Tnf,Mitd1,Irak2,Rcan1,Mcm6,Nr4a3,Tlr3,Ripk2,Hmox1,Inhba,Sh3bp4,Snx2,Ext1,Cacybp,Asns,Plek,Ccl5,Ifi207,Slc16a1,Mul1,Ifi214,Fas,Stxbp1,Col18a1,Optn,Mid1,Ggct,Bnip3,Ctsc,Nlrc4,Trip10,Srm,Sqstm1,Bcl2a1b,Sod2,Ass1,Ccl4,Ldlr,Odc1,Ifi204,Ifit3b,Max,Hmgcs1,Mmp9,Csf1,Ifi211,Trim21,Cav1,Mndal,Nos2,Nfkb1,Ikbkg,Daxx,Ripk3,Nod1,Ddx58,Stat2,Trim12c,Jmjd6,Hhex,Mcm10,Pml,Acvr1,Lztfl1,Mdm2,Bcl2a1d,Acpp,Ifi205,Slc2a1,Gpsm2,Ifi213,Lrp4,Zhx2,Bcl2a1a,Gca,Thbs1,Ptgs2,Il12b,Ldha,Adora2a,Pdgfb,Ifi208,Daam1,Nampt,Mthfd1l,Gch1,Chmp4b,Tap1,Prdx1,Fbxo4,Prnp,Atf3,Nqo1,Kcnj2,Jun,Nfkbia,Flrt3,Pfkl,Igf1r,Actb,Adrb2,Cd200,Stat1,Dck,Sirt1,Ifi203,Dcp1a,Rasgrp1,Timeless,Trip13,Flnb,Ifit3 |
| 1.061e-04 | -9.15 | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_UP | 173 | 29 | 15632 | 1249 |
Gtpbp2,Zcchc2,Ust,Ap3m2,Endod1,Kdm6b,Cd200,Pik3cd,Phlpp2,Mmd,Cd69,Tbc1d13,Stx6,Dusp6,Irf8,Cd83,Traf5,Nod1,Herc3,Fbxo4,Gng11,Sla,Klf7,Ddx60,Sell,Il4ra,Dusp1,Abcc5,Ets2 |
| 1.061e-04 | -9.15 | GSE22886_TCELL_VS_BCELL_NAIVE_DN | MSigDB lists | GSE22886_TCELL_VS_BCELL_NAIVE_DN | 173 | 29 | 15632 | 1249 |
Sema3c,Myo1b,Irf8,Phlpp2,Timeless,Ifna6,Cd200,Il13ra1,Hmgcs1,Tnfsf4,Adam19,Tcf4,Ifna5,Mid1,Taf4b,Treml2,Stap1,Kcnj2,Fcgr2b,Kmo,Cd180,Fpr2,Hhex,Ifna2,Clec4e,Cd80,Fbxo4,Ifna1,Nod1 |
| 1.061e-04 | -9.15 | GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 173 | 29 | 15632 | 1249 |
Csf1,Gpr132,Akt3,Tlr1,Serpine1,Mthfd1l,Rnf14,Ikbkg,Cldnd1,Rap2c,Chic2,Gpr85,Ddx4,Itpkc,Cdyl2,Stk40,Pla2g4a,Tgs1,Pnp2,H2-Q6,D16Ertd472e,H2-Q4,N4bp1,Sqstm1,Slfn5,Cd180,Irf2,H2-Q7,Rhoh |
| 1.064e-04 | -9.15 | GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 335 | 47 | 15632 | 1249 |
Fzd5,Txn1,G3bp2,Csf3,Fzd1,Ptgs2,Il12b,Il18,Tlr3,Zc3h12a,Keap1,Il1b,Bambi,Tnf,Rbpms,Nfkbie,Mdm2,Micall2,Ddx58,Sphk1,Plk3,Nfkbil1,Parp10,Mdfic,Plagl2,Il10,Tnfsf14,Rnf31,Sirt1,Rhou,Slc9a1,Nfkbib,Tlr2,Tlr9,Dyrk2,Stard7,Cdkn1a,Jak2,Hcls1,Psmd10,Nfkbia,Ccl12,Il6,Cdk5r1,Nlrp3,Angpt1,Prdx1 |
| 1.065e-04 | -9.15 | ruffle | cellular component | GO:0001726 | 144 | 23 | 20747 | 1409 |
Asap3,Fgr,Src,Itga5,Pdlim7,Myo10,Ezr,Arf4,Ddx58,Itgav,Dbnl,Mtmr14,Palld,Psd,Ptprj,Cyth3,Spata13,Tmod3,Fscn1,Pdpn,Psd4,Myadm,Plek |
| 1.073e-04 | -9.14 | FAS pathway and Stress induction of HSP regulation | WikiPathways | WP571 | 37 | 13 | 4813 | 540 |
Tnf,Fas,Apaf1,Map2k4,Jun,Casp3,Il1a,Cflar,Daxx,Ripk2,Mapkapk2,Casp7,Casp8 |
| 1.074e-04 | -9.14 | GO_RESPONSE_TO_GROWTH_FACTOR | MSigDB lists | GO_RESPONSE_TO_GROWTH_FACTOR | 460 | 60 | 15632 | 1249 |
Fos,Zyx,Jun,Cx3cr1,Flt1,Nr4a1,Ccl12,Flrt3,Edn1,Myc,Il6,Fas,Egr1,Mapkapk2,Lrp8,Spred1,Col4a2,Plau,Cav1,Il10,P2ry2,Nfkb1,Tnfrsf1b,Ltbp2,Egr3,Ptk2,Polr2g,Kdr,Src,Ehd1,Lrp4,Mdm2,Kdm5b,Acvr1,Errfi1,Acvrl1,Fut8,Casp3,Tnc,F11r,Sphk1,Ier2,Pml,Apaf1,Notch1,Bmp2,Flrt2,Pdgfrb,Ccl5,Gdf15,Dusp6,Rapgef2,Fzd1,Hap1,Pdgfb,Nrp2,Ddit4,Vcam1,Gcnt2,Bambi |
| 1.076e-04 | -9.14 | negative regulation of nitric oxide biosynthetic process | biological process | GO:0045019 | 18 | 7 | 20694 | 1406 |
Zc3h12a,Acp5,Cd34,Atp2b4,Tspo,Cav1,Il10 |
| 1.076e-04 | -9.14 | negative regulation of nitric oxide metabolic process | biological process | GO:1904406 | 18 | 7 | 20694 | 1406 |
Acp5,Zc3h12a,Atp2b4,Cd34,Il10,Tspo,Cav1 |
| 1.077e-04 | -9.14 | regulation of binding | biological process | GO:0051098 | 403 | 48 | 20694 | 1406 |
Mecp2,Ubash3b,Bambi,Jun,Hopx,Adrb2,Met,Angpt1,Il10,Plaur,Pim2,Eno1,Kat2b,Dnajb2,Itga4,Dtx3l,Myc,Aida,Irf4,Actb,Mark2,Txn1,Agrn,Pdgfb,Slpi,Lif,Traf2,Parp9,Ripk2,Ifit2,Lox,Plk2,Rapgef2,Lhx2,Mitd1,Plscr1,Src,Csf3,Bmp2,Jak2,Crbn,Cav1,Hmox1,Plcl2,Mmp9,Sirt1,Trib3,Lgals9 |
| 1.080e-04 | -9.13 | BZIP | prosite domains | PS50217 | 51 | 13 | 13278 | 1037 |
Batf2,Maff,Nfil3,Mafg,Jdp2,Atf3,Batf,Cebpd,Mafk,Fos,Junb,Fosb,Jun |
| 1.083e-04 | -9.13 | INTFRNREGFCT | prints domains | PR00267 | 9 | 5 | 5821 | 374 |
Irf2,Irf1,Irf8,Irf4,Irf7 |
| 1.089e-04 | -9.13 | DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | 298 | 43 | 15632 | 1249 |
Ogfr,Ccne1,Alas1,Trim21,Irf1,Pim2,Ap3m2,Lhx2,Sqstm1,Ifit1bl1,H2-Q4,Nr4a1,Nat2,Aldh1b1,Nxf1,Trim13,Atf3,Prpf4,Cnp,Tuba4a,Brd2,Gch1,Ifit1bl2,Junb,Tyk2,Pdlim7,Btg2,Grina,Thbs1,Mgat1,H2-Q6,Cebpd,Hspa2,Ccng2,Nfkbie,Pnp2,Sat1,Casp3,Psmb10,Isg15,Hhex,H2-Q7,Daxx |
| 1.091e-04 | -9.12 | RHO | prosite domains | PS51420 | 21 | 8 | 13278 | 1037 |
Rac3,Rnd1,Rnd3,Rhoc,Rhoq,Rhou,Rhoh,Rhof |
| 1.095e-04 | -9.12 | GO_MOLECULAR_FUNCTION_REGULATOR | MSigDB lists | GO_MOLECULAR_FUNCTION_REGULATOR | 1220 | 133 | 15632 | 1249 |
Tor1aip2,Gclm,Ctsc,Mmp14,Rin2,Psd,Phactr4,Eif2ak2,Ppp1r14b,Rapgef5,Nlrc4,Trip10,Spred1,Nck1,Cdkn2d,Kat2b,Cyth3,Cdk5r1,Slc30a1,Irs2,Slpi,Ppp4r2,Psme2,Rictor,Rap1gap2,Plekhg1,Cav1,Adap2,Jak2,Arf4,Ppp2r1b,Cdkn1a,Ptk2,C3,Ptgir,Dennd2a,Trib1,Arhgap26,Errfi1,Prdx5,Dock10,Arhgef3,Sgk3,Rgs3,Apaf1,Rab3ip,Asap3,Sh3bp4,Rapgef2,Tbc1d13,Ppp2r3a,Spint2,Psd4,Ccl5,Flrt2,Tor1aip1,Ppp1r15a,Map2k1,Pdgfrb,Serpine1,Ralgds,Kitl,Htr2b,Ppp2r2a,Trib3,Rcan1,Il2rg,Cdc42ep4,Spry2,Prkce,Ppp2r5a,Il18bp,Flrt3,Pik3r5,Jun,Dock4,Cdc42ep2,Mark2,Atp2b4,Angpt1,Abr,Pttg1,Dcp1a,Rasgrp1,Rabgef1,Birc3,Ccne1,Tnfsf14,Cflar,Rgs1,Tagap,Socs7,Prkar2b,Socs3,Adrb2,Casp3,Tbc1d1,Cish,Dbnl,Dennd1b,Ccnd1,Hsph1,Cst7,Casp1,Rgs14,Itpr1,P2ry12,Timp1,Gpsm2,Birc2,Nod1,Bmp2,Ahsa1,Crim1,Daxx,Notch1,Psme1,Malt1,Rhoh,Spata13,Socs1,Pdgfb,Inpp5b,Scn1b,Rgl1,Sipa1l1,Pik3r6,Il1rn,Elmod2,Serpinb2,Cxcl10,Nsmaf,Serpinb9 |
| 1.097e-04 | -9.12 | Staphylococcus aureus infection | KEGG pathways | ko05150 | 51 | 14 | 7931 | 713 |
Fpr2,Ptafr,Itgal,C1ra,H2-Ab1,C3,Fcgr2b,H2-Eb1,Fpr1,Icam1,Fcgr4,H2-Aa,Fcgr1,Il10 |
| 1.097e-04 | -9.12 | Staphylococcus aureus infection | KEGG pathways | mmu05150 | 51 | 14 | 7931 | 713 |
Fpr2,Itgal,Ptafr,H2-Ab1,C1ra,Icam1,H2-Eb1,Fpr1,C3,Fcgr2b,Fcgr4,Il10,Fcgr1,H2-Aa |
| 1.099e-04 | -9.12 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN | MSigDB lists | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN | 50 | 13 | 15632 | 1249 |
Agrn,Itgav,Sema3c,Myc,Inhba,Fzd1,Sdc1,Cx3cl1,Col4a2,Gng11,Thbs1,Igf1r,Angpt1 |
| 1.099e-04 | -9.12 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PENTOSYL_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PENTOSYL_GROUPS | 50 | 13 | 15632 | 1249 |
Zc3hav1,Parp10,Parp3,Upp1,Parp11,Parp14,Pnp2,Sirt1,Parp9,Parp12,Parp8,Nampt,Tiparp |
| 1.102e-04 | -9.11 | response to peptidoglycan | biological process | GO:0032494 | 13 | 6 | 20694 | 1406 |
Myd88,Irak3,Tlr2,Nlrp3,Ripk2,Nod2 |
| 1.103e-04 | -9.11 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | 910 | 104 | 15632 | 1249 |
Hk3,Cd80,Pim3,Papss2,Irs2,Gmppb,Pikfyve,Cdk5r1,Nek6,Cept1,Sqstm1,Syk,Eif2ak2,Vrk2,Cdkn1a,Jak2,Polr2g,Lyn,Map2k4,Trib1,Oasl1,Pim2,Tlr9,Ptk2,Dgkh,Mmd,Sik3,Hk1,Atm,Irak3,Gys1,Sgk3,Plk3,Tlk2,Oas3,Stat5a,Pgk1,Kitl,Ikbke,Irak2,Map3k8,Trib3,Ripk2,Nrp2,Map2k1,Pdgfrb,Med21,Ccl5,Mark2,Pnpt1,Pfkfb3,Ciita,Sgms2,Mapkapk2,Pgs1,Prkce,Pik3r5,Ccl12,Map3k6,Flt1,Igf1r,Pfkl,Kdr,Fam20c,Pik3cd,Acvr1b,Dck,Dyrk2,Itpkc,Etnk1,Met,Oas1a,Akt3,Ksr1,Ccne1,Pdk3,Hck,Ripk3,Crim1,Sphk1,Fgr,Acvrl1,Mlkl,Stk40,Ccnd1,Acvr1,Ctu1,Src,Axl,Cmpk2,Prkx,Ak4,Pim1,Scyl2,Oas1g,Hk2,Tyk2,Oas2,Dgka,Pdgfb,Pik3r6,Cd86,Plk2,Map4k4 |
| 1.106e-04 | -9.11 | DAP12 interactions | REACTOME pathways | R-MMU-2172127 | 316 | 48 | 8608 | 757 |
Cd86,Jak2,Map2k1,Ksr1,Il2rg,Pdgfrb,Rictor,Irs2,Ppp2r5a,Kitl,Cdkn1a,Pdgfb,Prkar2b,Psme1,Dusp5,Psmb6,Dusp6,Rapgef2,Pde1b,Rasgrp1,Cd300e,Psme2,Cd80,Psma6,Trib3,Ptk2,Trem1,Met,Mdm2,Psmb8,Ier3,Syk,Ppp2r1b,Nr4a1,Prkce,Angpt1,Psme2b,Src,Phlpp2,Spred1,Lcp2,Pik3cd,Psmb9,Clec5a,Psmd10,Phlpp1,Klrk1,Psmb10 |
| 1.108e-04 | -9.11 | post-embryonic development | biological process | GO:0009791 | 135 | 22 | 20694 | 1406 |
Bcl2l11,Serp1,Plagl2,Fzd5,Arid5b,Prdm1,Sema3c,Tiparp,Tal2,Kdm5b,Tet2,Morc3,Itpr1,Kdr,Jak2,Csrnp1,Flt1,Mecp2,Atm,Ahr,Chst11,Sod2 |
| 1.109e-04 | -9.11 | DELACROIX_RARG_BOUND_MEF | MSigDB lists | DELACROIX_RARG_BOUND_MEF | 345 | 48 | 15632 | 1249 |
Pdlim7,Tyk2,Junb,Gdf15,Dusp6,Dmwd,Fubp1,Il1rn,Osbpl3,Kitl,Traf3ip2,Parp3,Fcho2,Sat1,Rhoq,Cp,Ccnd1,Gsr,Src,Lipe,Dusp1,Rhoc,Zfp319,Plagl2,Nupr1,Rnf139,F11r,Slc39a13,Atp11a,S100a8,Fscn1,Clcf1,Esd,Ifrd1,Rin2,Mllt6,Ankrd24,Dusp4,Bcl2l11,Sqstm1,Rhof,Hmga1,Rnd3,Zbp1,Dusp14,Cdkn2d,St3gal3,Ppm1l |
| 1.110e-04 | -9.11 | Ikbkb (inhibitor of kappaB kinase beta) | protein interactions | 16150 | 22 | 9 | 7778 | 753 |
Nfkbia,Optn,Nfkbib,Prdm1,Rnf31,Tnf,Cd40,Ikbkg,Cited2 |
| 1.110e-04 | -9.11 | GO_PLATELET_ACTIVATION | MSigDB lists | GO_PLATELET_ACTIVATION | 140 | 25 | 15632 | 1249 |
Dgka,Plscr1,Stxbp3,Pik3r6,Gna15,Lcp2,Csrp1,Plek,Pf4,Actb,Lyn,Dgkh,Pdpn,Il6,Prkce,Cd40,P2ry12,Itpr1,Pik3r5,Slc7a11,Syk,Src,Axl,Cx3cl1,Stxbp1 |
| 1.110e-04 | -9.11 | Interleukin-6 family signaling | REACTOME pathways | R-MMU-6783589 | 29 | 10 | 8608 | 757 |
Socs3,Stat3,Osm,Stat1,Il27,Clcf1,Ebi3,Il6,Jak2,Lif |
| 1.112e-04 | -9.10 | GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION | MSigDB lists | GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION | 108 | 21 | 15632 | 1249 |
Rictor,Csf3,Ifnb1,Ifna5,Spry2,Ddit4,Ifna6,Il6,Cav1,Osm,Txn1,Tnf,Atp2b4,Angpt1,Ifna2,Plcl2,Ifna1,Hcls1,Nck1,Ripk2,Lif |
| 1.114e-04 | -9.10 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN | 182 | 30 | 15632 | 1249 |
Nat2,Ccdc86,Casp3,Minpp1,Cox17,Apobec3,Eno1,Itpr1,Batf,Rnf34,Sdc4,Rras2,Rbl1,Tap1,Mcmbp,Tpi1,Plagl1,Alas1,Slc25a12,Ccr1,Med21,Vps54,Tor1aip1,Tnfsf10,Ldlr,Gfi1,Stard7,Etnk1,Mthfd2,Dnajb4 |
| 1.114e-04 | -9.10 | GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP | MSigDB lists | GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP | 182 | 30 | 15632 | 1249 |
Kmo,Sell,Cdk5r1,Marcksl1,Hck,Gpc1,Cd14,Gpr18,Mtus1,Timp1,Tcf4,Tnf,Plac8,B3gnt5,Phgdh,Igsf6,Stard5,Arid5b,Atp10a,Dram1,C3,Trem1,Nfil3,Irf8,Cd86,Lcn2,Egln3,Cd69,Pou2f2,Cnn3 |
| 1.114e-04 | -9.10 | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_UP | MSigDB lists | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_UP | 182 | 30 | 15632 | 1249 |
Slco3a1,P2ry14,Prdm1,Prrg4,Samhd1,Pilrb2,Nod1,Slamf7,Gpc1,Swap70,Ptpn2,Zyx,Plac8,Fcgr2b,Ctsc,Rcn1,Fam111a,Ier3,Dusp5,Epsti1,Pilrb1,Adam19,Golga3,Plek,Myadm,Ccl5,Ccrl2,Smpdl3b,Rap1gap2,AA467197 |
| 1.114e-04 | -9.10 | GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_UP | MSigDB lists | GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_UP | 182 | 30 | 15632 | 1249 |
Csf1,Sap30,Alas1,Mmd,Smpdl3b,Gna15,Gfpt1,Ppp2r1b,Rgs1,Lhx2,Nfil3,Casp7,Serpinb9,Mafg,Map2k4,Carhsp1,Optn,Errfi1,Mlkl,Trmt1l,Tspan3,Rhbdf2,Hspa1a,Sgcb,Myd88,Cd80,Clcn5,Irak3,Rhoc,Dnase1l3 |
| 1.114e-04 | -9.10 | GSE4748_CTRL_VS_LPS_STIM_DC_3H_UP | MSigDB lists | GSE4748_CTRL_VS_LPS_STIM_DC_3H_UP | 182 | 30 | 15632 | 1249 |
Irgm2,Edn1,Egr2,Ifi44,Rin2,Errfi1,Slc25a37,Bcl2l11,Slc16a3,Itgav,Ankrd17,Sav1,Rnd3,Ifit1,Spred1,Sertad3,Rtp4,Ampd3,Inhba,Rnf19a,Mmp13,Cav1,Ifit3,Serpine1,Ptch1,Mitd1,Frmd6,Ifi35,Fndc3a,Ifit3b |
| 1.114e-04 | -9.10 | GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_UP | 182 | 30 | 15632 | 1249 |
Sertad3,Cdk5r1,Sgcb,Pilrb2,Gclc,Stau1,Axl,Sqstm1,B4galt4,Cd302,Ikzf1,Carhsp1,Il18bp,Dnaja2,Osgin2,Rcan1,Kif3c,Tlr2,Clcn7,Pilrb1,Snx10,Slc31a2,Ednrb,Asah2,Lgals9,Itgal,Golga3,Akt3,Htra1,Eef1e1 |
| 1.114e-04 | -9.10 | GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN | MSigDB lists | GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN | 182 | 30 | 15632 | 1249 |
Il1a,Gbp3,Znrf3,Rnf135,Magohb,Tpi1,Rbl1,Sla,Ttc39c,Chst11,Hspa2,Ctsc,Tmem171,Carhsp1,Casp7,Ptprj,5430427O19Rik,Gfi1,Osbpl3,Irak2,Plekha2,Gbp7,Myadm,Nfkb1,Rapgef2,Rap1gap2,Tyk2,Sap30,Reps1,Cysltr2 |
| 1.116e-04 | -9.10 | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_DN | 165 | 28 | 15632 | 1249 |
Dse,Rbbp8,Tnf,Nr4a1,Bcl2a1b,Cox17,Bcl2a1d,Irf4,Egr2,Cish,Arg2,Magohb,Egr1,Lif,Dusp14,Med21,Sipa1l1,Dcun1d3,Stx6,Vasp,Phlda1,Mthfd2,Egr3,Cd200,Mob3c,Osbpl3,Bcl2a1a,Fam102b |
| 1.118e-04 | -9.10 | response to growth factor | biological process | GO:0070848 | 437 | 51 | 20694 | 1406 |
Ehd1,Jun,Vegfc,Cited2,Kdr,Bambi,Pml,Il10,Zyx,Acvr1,Ddit4,Nr4a1,Apaf1,Ccl2,Col4a2,Acvrl1,Flrt2,Spry2,Serpine1,Egr1,Fut8,Igf1r,Ptk2,Gdf15,Zfp36,Pdgfrb,Dcp1a,Ier2,Fos,Pdgfb,Il6,Acvr1b,Flt1,Hap1,Bmp2,Nr3c1,Rapgef2,Nrp2,Src,Gcnt2,Egr3,Nfkb1,Cav1,Prkce,Crkl,Sphk1,Casp3,Flrt3,Mapkapk2,Notch1,Sirt1 |
| 1.129e-04 | -9.09 | Adipogenesis genes | WikiPathways | WP447 | 133 | 30 | 4813 | 540 |
Stat1,Ahr,Nampt,Nr3c1,Cebpd,Tle3,Tnf,Fas,Irs2,Socs1,Stat5a,Egr2,Bmp2,Trib3,Stat2,Hmga1,Rbl1,Klf7,Nr1h3,Klf6,Il6,Hif1a,Serpine1,Lipe,Stat3,Lif,Socs3,Osm,Gadd45b,Fzd1 |
| 1.132e-04 | -9.09 | cellular response to decreased oxygen levels | biological process | GO:0036294 | 108 | 19 | 20694 | 1406 |
Sirt1,Adrb2,Slc9a1,Cpeb4,Myc,Bnip3,Notch1,Pdk3,Hif1a,Higd1a,Cited2,Ak4,Rgcc,Prkce,Vasn,Plk3,Egr1,Fam162a,Pgk1 |
| 1.134e-04 | -9.08 | MODULE_188 | MSigDB lists | MODULE_188 | 116 | 22 | 15632 | 1249 |
Icosl,Spint2,Oas1a,Heatr6,Irf8,Tnfaip2,Cmklr1,Sp110,5430427O19Rik,Oas1g,Cd200,Rcsd1,Kcna3,Fcgr2b,Rsad2,Mecp2,Abcc5,Plac8,Tap1,Hvcn1,Il4ra,Fgr |
| 1.138e-04 | -9.08 | establishment of protein localization to extracellular region | biological process | GO:0035592 | 154 | 24 | 20694 | 1406 |
Rab10,Tlr2,Lyn,Notch2,Nod2,Lcp2,Tlr6,Stxbp3,Itgav,Nlrc4,Traf3ip2,Il1rn,Notch1,Nlrp3,Isg15,Rnf19b,Svbp,Optn,Pou2f2,Nos2,Aim2,Mcoln2,Trem1,Plek |
| 1.140e-04 | -9.08 | regulation of oxidative stress-induced cell death | biological process | GO:1903201 | 74 | 15 | 20694 | 1406 |
Hif1a,Nox1,Tlr6,Nr4a3,Ncoa7,Slc7a11,Fzd1,Sod2,Hk3,Sirt1,Met,Hsph1,Glrx,Txn1,Il10 |
| 1.150e-04 | -9.07 | PEART_HDAC_PROLIFERATION_CLUSTER_DN | MSigDB lists | PEART_HDAC_PROLIFERATION_CLUSTER_DN | 78 | 17 | 15632 | 1249 |
Il2rg,Ifi214,Ifi204,Tnfrsf8,Gfi1,Ifi207,Ifi213,Eif2ak2,Ifi205,Hmga1,Ifi209,Mndal,Katna1,Myc,Ifi208,Ifi211,Ifi203 |
| 1.155e-04 | -9.07 | ABE_VEGFA_TARGETS_30MIN | MSigDB lists | ABE_VEGFA_TARGETS_30MIN | 26 | 9 | 15632 | 1249 |
Egr3,Nr4a1,Egr1,Dusp5,Ptgs2,Rcan1,Trib1,Hdc,Egr2 |
| 1.155e-04 | -9.07 | ST_GAQ_PATHWAY | MSigDB lists | ST_GAQ_PATHWAY | 26 | 9 | 15632 | 1249 |
Itpr1,Ikbkg,Nfkb1,Nfkbia,Nfkbil1,Nfkbie,Nfkbib,Nfkb2,Akt3 |
| 1.155e-04 | -9.07 | GO_POSITIVE_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING | MSigDB lists | GO_POSITIVE_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING | 26 | 9 | 15632 | 1249 |
Nod2,Tnfsf15,Nod1,Traf2,Tlr6,Tlr3,Tnf,Eif2ak2,Malt1 |
| 1.155e-04 | -9.07 | GO_NEGATIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 26 | 9 | 15632 | 1249 |
Irak3,Tnfaip3,Smpdl3b,Cd14,Irf4,Lyn,Tlr3,Tlr9,Nfkbil1 |
| 1.157e-04 | -9.06 | GSE3982_EOSINOPHIL_VS_TH1_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_TH1_DN | 191 | 31 | 15632 | 1249 |
Ifi203,Eef1e1,Ifi208,Pdss1,Ifi211,Trim14,Mndal,Plod2,Asns,Psmb8,Gfi1,Ccl4,Phyh,Ifi204,Slc31a1,Ifi35,Pnp2,Irf4,D1Ertd622e,Minpp1,Ifi205,Eno1,Ifi209,Apobec3,Ifi213,Mdfic,Ifi207,Prdx1,Ifi214,Pttg1,Malt1 |
| 1.157e-04 | -9.06 | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_DN | MSigDB lists | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_DN | 191 | 31 | 15632 | 1249 |
Card6,Myadm,Ifit1bl2,Dmwd,Dgka,Snx2,Pik3cd,Prkx,Ralgds,Orai2,Clcf1,Tagap,Ifit1bl1,Klf3,Rhof,Bcl6,Arhgef3,Fchsd2,Lrch1,Il4i1,Dusp2,Prdx5,B3gnt5,Pml,Ier2,Il4ra,Pikfyve,Gbe1,Ciita,Hvcn1,Daxx |
| 1.157e-04 | -9.06 | GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_UP | MSigDB lists | GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_UP | 191 | 31 | 15632 | 1249 |
Mthfd1l,Syne2,H2-Aa,Pdlim7,Irf1,Nfil3,Lrrc8c,Cacna1d,Timp1,H2-Q6,Trip10,H2-Q4,Axl,Ezr,Sqstm1,Ddhd1,Slc7a11,Mdm2,Ccnd1,Il18bp,Cd74,Spata13,Nlrp3,Papss2,Ppm1l,H2-Q7,Mxd1,Plk3,Slc28a2,Col4a2,Clec4e |
| 1.157e-04 | -9.06 | GSE2826_XID_VS_BTK_KO_BCELL_DN | MSigDB lists | GSE2826_XID_VS_BTK_KO_BCELL_DN | 191 | 31 | 15632 | 1249 |
Vcam1,Glrx,Plaur,C3,Hp,Ebi3,Etnk1,Casp7,Il2rg,Irf1,Inpp5b,Caml,Pla2g7,Bst1,Ikbkg,S100a8,Lcn2,Mvp,Tap1,Chmp4b,Ifih1,F11r,Prnp,Il1a,Ccl2,Minpp1,Cpd,Sele,Abcc5,Ccl12,Spic |
| 1.157e-04 | -9.06 | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | MSigDB lists | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | 191 | 31 | 15632 | 1249 |
Antxr1,Inhba,Mthfd1l,Plk2,Asns,Rgs1,Col27a1,Vcam1,Cxcl1,Fscn1,Lacc1,Vegfc,C3,Socs3,Usp31,Dram1,Aida,Micall2,Tnc,Cxcl14,C1ra,Ppp1r14b,Tagln,Plod3,Ccl12,Axl,Timp1,Cyfip1,Msr1,Pdgfc,Nfkbiz |
| 1.162e-04 | -9.06 | Activation of NF-kappaB in B cells | REACTOME pathways | R-MMU-1169091 | 65 | 16 | 8608 | 757 |
Nfkbib,Rel,Psmb6,Psme1,Psmb9,Nfkbie,Nfkbia,Psma6,Psme2,Psme2b,Malt1,Psmd10,Psmb8,Nfkb1,Ikbkg,Psmb10 |
| 1.166e-04 | -9.06 | GO_REGULATION_OF_JNK_CASCADE | MSigDB lists | GO_REGULATION_OF_JNK_CASCADE | 157 | 27 | 15632 | 1249 |
Daxx,Mdfic,Nod1,Il1a,Mul1,Tlr6,Phlpp1,Nod2,Gadd45g,Edn1,Dbnl,Traf2,Dnaja1,Gadd45b,Map3k6,Tnf,Syk,Igf1r,Il1b,Aida,Nox1,Tlr3,Tlr9,Ripk2,Rasgrp1,Fzd5,Map4k4 |
| 1.177e-04 | -9.05 | GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | MSigDB lists | GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 327 | 46 | 15632 | 1249 |
Cdc42ep2,Rnd3,Rras2,Rhoc,Rhoh,Mapkapk2,Abr,Rnd1,Arl4a,Nkiras1,Rab19,Dbnl,Rab9,Rhoq,Rab21,Dock10,Phactr4,Rin2,Rapgef5,Rab32,Jun,Rhof,Bcl6,Dock4,Arhgef3,Cyfip1,Ralgds,Rap2c,Arf4,Cdkn1a,Rac3,Hmox1,Arl5c,Crkl,Rab20,Cdc42ep4,Arl5b,Ksr1,Rab10,Rasgrp1,Rhou,Rapgef2,G3bp2,Rgl1,Gem,Plk2 |
| 1.179e-04 | -9.05 | GSE3982_EOSINOPHIL_VS_NKCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_NKCELL_UP | 174 | 29 | 15632 | 1249 |
Jag1,Tnfsf14,Thbs1,Rgs1,Inpp1,Bcl2a1a,Vcam1,Orai2,Notch2,Jak2,Snn,Glrx,Nfil3,Pgk1,H3f3b,Nsmaf,Rnf24,Bcl2a1d,Rsad2,Treml2,Arhgap26,Bcl2a1b,Bcl6,Acpp,Swap70,Sla,Ahr,Mthfr,Zfp281 |
| 1.179e-04 | -9.05 | GSE15659_RESTING_TREG_VS_NONSUPPRESSIVE_TCELL_DN | MSigDB lists | GSE15659_RESTING_TREG_VS_NONSUPPRESSIVE_TCELL_DN | 174 | 29 | 15632 | 1249 |
Prdm1,Pml,Pigv,Pnpt1,Vcpip1,Rhoc,Trim36,Timp1,Rhbdf2,Tbc1d1,Rab9,S1pr2,Rbpms,Psma6,Slc43a3,Sema4a,Prkx,Prkar2b,Pf4,Samsn1,Tor1aip1,Phlda1,Ppp4r2,Wars,Rnf19a,Rhou,Xaf1,Tdrd7,Tyk2 |
| 1.179e-04 | -9.05 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP | 174 | 29 | 15632 | 1249 |
Rbms2,Sgk3,Etv3,Cyth3,Plk3,Bcor,Mapkapk2,Il18bp,Abcb1a,Dusp2,Arid5a,Bcl6,Klf3,Clcf1,Bambi,Idi1,Acsl1,Kdm6b,Zc3h12a,Itga5,Mmp9,Sirt1,Rapgef2,Spen,Zfp36,Rel,Fosb,Rabgef1,Pde4b |
| 1.179e-04 | -9.05 | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_DN | MSigDB lists | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_DN | 174 | 29 | 15632 | 1249 |
Tiparp,Rhbdf2,Rhof,Homer1,Cst7,Parp8,Aoah,Cx3cr1,Dpy19l1,Arhgap26,Dusp2,Phgdh,Abcb1a,Jmjd6,Crim1,Rgs3,Slamf7,Ptch1,Hopx,Itgal,Ccl5,Plek,Maff,Procr,Adrb2,Map3k8,Ralgds,Ccl4,Vcam1 |
| 1.179e-04 | -9.05 | PID_ATF2_PATHWAY | MSigDB lists | PID_ATF2_PATHWAY | 57 | 14 | 15632 | 1249 |
Junb,Dusp1,Jdp2,Fos,Jun,Nos2,Dusp8,Il6,Ccnd1,Sele,Atf3,Dusp5,Socs3,Plau |
| 1.181e-04 | -9.04 | adenylyltransferase activity | molecular function | GO:0070566 | 36 | 10 | 20217 | 1400 |
Oasl1,Oas1g,Oas2,Tent2,Tent4a,Oasl2,Oas1b,Oas1a,Papss2,Oas3 |
| 1.188e-04 | -9.04 | filopodium | cellular component | GO:0030175 | 91 | 17 | 20747 | 1409 |
Antxr1,Cd302,Itgav,Vasp,Cyfip1,Myo1b,Acpp,Dync1h1,Palld,Syne2,Vcam1,Fscn1,Spata13,Ezr,Kitl,Myo10,Pdpn |
| 1.190e-04 | -9.04 | branching morphogenesis of an epithelial tube | biological process | GO:0048754 | 164 | 25 | 20694 | 1406 |
Angpt1,Met,Src,Timeless,Acvr1,Bmp2,Pml,Kdr,Flt1,Tnc,Cited2,Myc,Kdm5b,Hmga2,Hhex,Notch1,Mmp14,Ptch1,Edn1,Tmem67,Clic4,Csf1,Pbx1,Ahr,Spry2 |
| 1.195e-04 | -9.03 | transferase activity, transferring pentosyl groups | molecular function | GO:0016763 | 50 | 12 | 20217 | 1400 |
Parp10,Parp14,Upp1,Parp9,Zc3hav1,Parp8,Parp12,Parp3,Pnp2,Nampt,Parp11,Tiparp |
| 1.207e-04 | -9.02 | GO_POSITIVE_REGULATION_OF_B_CELL_ACTIVATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_B_CELL_ACTIVATION | 64 | 15 | 15632 | 1249 |
Clcf1,Cdkn1a,Cd38,Prdm1,Tnfsf4,Irs2,Cd74,Il6,Peli1,Mmp14,Nod2,Bst1,Syk,Cd40,Bcl6 |
| 1.211e-04 | -9.02 | ONDER_CDH1_TARGETS_1_DN | MSigDB lists | ONDER_CDH1_TARGETS_1_DN | 149 | 26 | 15632 | 1249 |
Mcm10,Slc16a1,Hsph1,Dnaja1,Edn1,Hmgcs1,Max,Scyl2,Slc43a3,Ptgs2,Cxcl1,Ppp2r1b,Serpinb2,Dcbld2,Il1b,Dusp6,Tor1aip1,Lcn2,P2ry2,Rrs1,Casp8,Phlda1,Csf3,Jag1,G3bp2,Cxcl2 |
| 1.211e-04 | -9.02 | LIU_CMYB_TARGETS_UP | MSigDB lists | LIU_CMYB_TARGETS_UP | 149 | 26 | 15632 | 1249 |
Slco3a1,Ak4,Tgfbi,Usp25,Pim2,Prkar2b,Glrx,Myo10,Mark2,Crim1,Trp53i11,Cited2,Tiparp,Ass1,Lnpep,Abtb2,Slc31a2,Nqo1,Mmd,Jag1,Phlpp1,Stard5,Rab11fip1,Isg20,Sat1,Sap30 |
| 1.218e-04 | -9.01 | protein kinase activity | molecular function | GO:0004672 | 599 | 66 | 20217 | 1400 |
Map4k4,Acvr1b,Acvrl1,Pdk3,Mark2,Pim2,Sgk3,Pim1,Cdkn1a,Map3k6,Ikbke,Ripk3,Plk3,Syk,Igf1r,Prag1,Pdgfrb,Stk40,Mapkapk2,Fam20c,Prkx,Src,Eif2ak2,Sla,Flt1,Ccng2,Ccnd2,Fgr,Hk1,Axl,Met,Map2k4,Map2k1,Jak2,Ccl5,Map3k8,Atm,Hck,Nek6,Mlkl,Trib3,Mmd,Sik3,Vrk2,Plk2,Prkce,Lyn,Tyk2,Nrp2,Ccne1,Kdr,Ripk2,Ccnj,Ksr1,Irak2,Ccnd1,Trib1,Irak3,Ptk2,Acvr1,Grk3,Dyrk2,Pim3,Tlk2,Scyl2,Akt3 |
| 1.220e-04 | -9.01 | GNF2_CD48 | MSigDB lists | GNF2_CD48 | 44 | 12 | 15632 | 1249 |
H2-Q4,H2-Q7,Psmb8,Phf11b,Phf11d,H2-Q6,Psmb10,Phf11a,Hcls1,Tapbp,Sp110,Phf11c |
| 1.220e-04 | -9.01 | MA_MYELOID_DIFFERENTIATION_DN | MSigDB lists | MA_MYELOID_DIFFERENTIATION_DN | 44 | 12 | 15632 | 1249 |
Cd14,Serpinb2,Vcam1,Notch1,Pde1b,Hspa2,Pla2g7,Stat4,Ccl12,Eif2ak2,Cited2,Fos |
| 1.224e-04 | -9.01 | negative regulation of viral transcription | biological process | GO:0032897 | 24 | 8 | 20694 | 1406 |
Hdac1,Ccl4,Trim21,Zfp36,Jun,Trim13,Trim14,Ccl5 |
| 1.224e-04 | -9.01 | granulocyte activation | biological process | GO:0036230 | 24 | 8 | 20694 | 1406 |
Dnase1l3,Syk,Il18,Fcgr4,Il18rap,Stx11,Il15,Ccl5 |
| 1.225e-04 | -9.01 | 1-phosphatidylinositol-3-kinase regulator activity | molecular function | GO:0046935 | 13 | 6 | 20217 | 1400 |
Cish,Socs3,Pik3r6,Socs7,Socs1,Pik3r5 |
| 1.228e-04 | -9.01 | GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_BIOSYNTHETIC_PROCESS | 16 | 7 | 15632 | 1249 |
Il10,Spn,Mapkapk2,Errfi1,Tnfrsf8,Thbs1,Tlr1 |
| 1.228e-04 | -9.01 | BIOCARTA_CDMAC_PATHWAY | MSigDB lists | BIOCARTA_CDMAC_PATHWAY | 16 | 7 | 15632 | 1249 |
Tnf,Nfkbia,Nfkb1,Fos,Map2k1,Jun,Myc |
| 1.228e-04 | -9.01 | GO_REGULATION_OF_MONONUCLEAR_CELL_MIGRATION | MSigDB lists | GO_REGULATION_OF_MONONUCLEAR_CELL_MIGRATION | 16 | 7 | 15632 | 1249 |
Cx3cl1,Ccl5,Ccl12,Tnf,Thbs1,Cmklr1,Csf1 |
| 1.228e-04 | -9.01 | MAINA_VHL_TARGETS_DN | MSigDB lists | MAINA_VHL_TARGETS_DN | 16 | 7 | 15632 | 1249 |
Ccnd1,Tnfsf10,Bnip3,Gbe1,Gng4,Slc16a3,Eno2 |
| 1.228e-04 | -9.01 | GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS | 16 | 7 | 15632 | 1249 |
Nlrp3,Il10,Psmd10,Zc3h12a,Nfkbia,G3bp2,Nfkbib |
| 1.228e-04 | -9.01 | GO_REGULATION_OF_MACROPHAGE_CHEMOTAXIS | MSigDB lists | GO_REGULATION_OF_MACROPHAGE_CHEMOTAXIS | 16 | 7 | 15632 | 1249 |
Cx3cl1,Ccl5,Ccl12,Cmklr1,Csf1,Thbs1,Stap1 |
| 1.228e-04 | -9.01 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | MSigDB lists | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | 16 | 7 | 15632 | 1249 |
Nod1,Irak2,Nod2,Ripk2,Ikbkg,Mapkapk2,Tab2 |
| 1.231e-04 | -9.00 | IPT_NFkappaB | interpro domains | IPR033926 | 5 | 4 | 19984 | 1430 |
Nfkb1,Relb,Nfkb2,Rel |
| 1.231e-04 | -9.00 | NFkB/Dor | interpro domains | IPR000451 | 5 | 4 | 19984 | 1430 |
Rel,Nfkb2,Relb,Nfkb1 |
| 1.231e-04 | -9.00 | RHD_CS | interpro domains | IPR030492 | 5 | 4 | 19984 | 1430 |
Relb,Nfkb1,Rel,Nfkb2 |
| 1.232e-04 | -9.00 | GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP | MSigDB lists | GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP | 183 | 30 | 15632 | 1249 |
Pim1,Mthfd2,Adrb2,Il18,Rnf19b,Ptprj,Ripk2,Ell2,Rnaset2b,Nfil3,Adam19,Inpp1,Rnaset2a,Gna15,Egln3,Psme2,Icam1,Gbp3,Sertad3,Prdm1,Crlf3,Traf5,Sla,Cyfip1,Klf3,Axl,Itgav,Rin2,Hspa2,Pnp2 |
| 1.232e-04 | -9.00 | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN | MSigDB lists | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN | 183 | 30 | 15632 | 1249 |
Nr4a1,Spsb1,Abcc5,Fos,Rgs14,Gclm,Myc,Acvrl1,Slc30a4,Fas,Tulp3,Sell,Traf5,Gnb4,Rab3ip,Klf7,Pde4b,Map4k4,Klf2,Pdgfrb,Cnn3,Ddit4,Zfp36,Slc7a5,Dgka,St3gal1,Socs3,Ttc39b,Adrb2,Igf1r |
| 1.232e-04 | -9.00 | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | 183 | 30 | 15632 | 1249 |
Src,Map3k6,Swap70,Rbbp8,Fcgr2b,Stat3,Rnf24,Sdc2,Phlpp1,Rsad2,Papss2,Il4ra,Arg2,Adar,Cd14,Stau1,Pdgfc,Mark2,Olr1,4930523C07Rik,Hk1,Med21,Sipa1l1,Akt3,Nrp2,Plscr1,Tdrd7,Mob3b,Esd,Gng12 |
| 1.232e-04 | -9.00 | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | 183 | 30 | 15632 | 1249 |
Sgms2,Papss2,Rnd3,Bfar,Tspo,Clec4e,Sla,Gpc1,Chmp4b,Cx3cr1,Plod3,Acvr1,Cers6,Denr,Mppe1,Ak4,Ddx4,Mefv,Dio2,Rcl1,Nfil3,Mthfd1l,Itgal,Irf8,Daam1,Pdgfrb,Slpi,Plscr1,Phlpp2,Il18rap |
| 1.234e-04 | -9.00 | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN | 860 | 99 | 15632 | 1249 |
Ift57,Pla2g4a,Dnaja1,Gadd45b,Ppp1r14b,Srm,Sod2,Dhrs9,Atp11b,Kif9,Col4a2,Fbrsl1,Lpcat2,Slc16a1,Ciapin1,Ubash3b,Aldh1b1,Znrf3,Arl4a,Nr1h3,Fas,Kctd12,Trim14,Sco1,Fam162a,Wdr43,Rpgrip1l,Fam102b,Fscn1,Trib1,Asb13,Dram1,1110038F14Rik,Slc39a4,Homer1,Tcf4,Cd302,Abcc5,Gnb4,Cutc,Slc25a12,Sap30,Rrs1,Slc12a9,Pkp4,Stip1,Rcl1,Pgk1,Kitl,Gpr85,Cdc42ep4,Naa25,Taf4b,Ikzf1,Tgs1,Myc,Rhof,Rab32,Hivep2,Prdx1,Egr1,Hivep3,Slc39a14,Ube2e2,Trip13,P2ry2,Dach1,Rnaset2b,Prkar2b,Armc8,Adrb2,Dyrk2,Ccnd1,Mlkl,Tbc1d1,Pnp2,Ccdc86,Acpp,Slc2a1,Hsph1,Myo10,Mdfic,Ahsa1,Itga4,Noc4l,Rnaset2a,Fubp1,Sesn3,Dcbld2,Fmnl2,Abcc4,Tfec,Trafd1,Acsl5,Slc43a3,Ak4,Slamf8,Ptger4,Ldha |
| 1.236e-04 | -9.00 | GO_EXTRACELLULAR_SPACE | MSigDB lists | GO_EXTRACELLULAR_SPACE | 1180 | 129 | 15632 | 1249 |
Csf3,Ifna6,Tnfsf15,Pdgfb,Cnp,Rnaset2a,Nampt,Pf4,Vegfc,Il15ra,Tnfsf10,Thbs1,Serpinb2,Il1rn,Serpinb9,Il12b,Lox,Cxcl10,Tgfbi,C1ra,Eno1,Cd40,Hspa1a,Slc2a1,Timp1,Acpp,Axl,Bmp2,Icam1,Il1a,Lif,Smpdl3b,Pla2g7,Htra1,Lcn2,C1rl,Tnfsf14,Il10,Ltbp2,Eno2,Nlgn2,Rnaset2b,Tnfaip2,Fam20c,Actb,Clcf1,Sema4a,Tnfsf4,Ebi3,Cxcl14,Ncoa5,Il18bp,Il6,Ccl2,Tgs1,Edn1,Msr1,Flrt3,Ccl12,Ezr,Flt1,Angpt1,Prdx1,Ifna1,Plau,Il4ra,Dmxl2,Ccl22,Cxcl2,Inhba,Mmp13,Vasn,Serpine1,Osm,Flrt2,Ccl5,Gdf15,H2-Eb1,Il1b,Kitl,Plat,Cxcl1,Vcam1,Il18,Hmox1,Hp,Prdx5,Hspa2,Fgl2,Sele,Mecp2,Tnfsf8,Cp,Tnc,Oas3,Mtus1,Tnf,Tsku,Ifna2,Ccl3,Pdgfc,Cd14,Lipg,Fabp3,Slpi,Csf1,Mov10,Sema3c,S100a8,Ppfibp2,Ldlr,Ccl4,Mthfd2,Mmp9,C3,Sema4c,Ifnb1,Cpd,Ifna5,Vcan,Ctsc,Spn,Gpc1,Il27,Il15,Cx3cl1,Col18a1,Tpi1,Fas |
| 1.242e-04 | -8.99 | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 166 | 28 | 15632 | 1249 |
Hivep3,Il18rap,Ampd3,Flrt2,Cenpj,Txn1,Tnfrsf1b,Ccl5,Keap1,Pmepa1,Tgfbi,Odc1,Adrb2,St7,Ell2,Sat1,Il4i1,Dse,Flt1,Parp8,Dpy19l1,Tnf,Cenpe,Pfkfb3,Cd34,Prdm1,Mcoln2,Mapkapk2 |
| 1.242e-04 | -8.99 | BENPORATH_NOS_TARGETS | MSigDB lists | BENPORATH_NOS_TARGETS | 166 | 28 | 15632 | 1249 |
Mndal,Cdyl,Jarid2,Gja1,Dusp6,Ifi203,Ppp2r3a,Ifi211,Ifi208,Ifi204,Kdr,Ppp2r1b,Bambi,Ifi209,Ifi205,Ptpn2,Ifi213,Tnc,Stat3,Slc44a1,Rnf24,Ifi214,Hhex,Ifi207,Spred1,Tle3,Olfml3,Prpf38a |
| 1.246e-04 | -8.99 | outer membrane | cellular component | GO:0019867 | 184 | 27 | 20747 | 1409 |
Mul1,Ass1,Acsl1,Gja1,Trim14,Prnp,Tspo,Cnp,Agpat4,Armcx6,Bcl2a1d,Bcl2a1b,Ppp1r15a,Acsl5,Hk2,Rmdn3,Tomm70a,Bcl2a1a,Hk1,Snn,Rsad2,Bnip3,Slc44a1,Rab32,Gk,Syne2,Kmo |
| 1.246e-04 | -8.99 | organelle outer membrane | cellular component | GO:0031968 | 184 | 27 | 20747 | 1409 |
Snn,Bnip3,Rsad2,Slc44a1,Rab32,Kmo,Gk,Syne2,Hk2,Rmdn3,Tomm70a,Bcl2a1a,Hk1,Cnp,Agpat4,Bcl2a1d,Armcx6,Bcl2a1b,Ppp1r15a,Acsl5,Mul1,Gja1,Acsl1,Ass1,Trim14,Tspo,Prnp |
| 1.254e-04 | -8.98 | positive regulation of supramolecular fiber organization | biological process | GO:1902905 | 184 | 27 | 20694 | 1406 |
Rhoc,Rac3,Gda,Swap70,Rgcc,Icam1,Spire1,Prkce,Rictor,Carmil1,Cav1,Edn1,Sdc4,Csf3,Plek,Met,Cdc42ep2,Cdc42ep4,Whamm,Evl,Nck1,Cx3cl1,Vasp,Fchsd2,Lpar1,Mecp2,Cyfip1 |
| 1.271e-04 | -8.97 | DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | 86 | 18 | 15632 | 1249 |
Nr3c1,Cdyl2,Sh3bp4,Egln3,Ccng2,Parp9,Plekhf2,Abcc5,Sesn3,Myo1b,Dram1,Ptger4,Uaca,Tmtc2,Rcan1,Kat2b,Rnd1,Arid5b |
| 1.271e-04 | -8.97 | GO_ENDOTHELIUM_DEVELOPMENT | MSigDB lists | GO_ENDOTHELIUM_DEVELOPMENT | 86 | 18 | 15632 | 1249 |
Col18a1,Kdm6b,F11r,Icam1,Clic4,Rap2c,Kdr,Cd34,Notch1,Gja1,Myadm,Plod3,Ezr,Met,Acvrl1,Jag1,Rapgef2,Acvr1 |
| 1.271e-04 | -8.97 | GO_B_CELL_DIFFERENTIATION | MSigDB lists | GO_B_CELL_DIFFERENTIATION | 86 | 18 | 15632 | 1249 |
Atm,Klf6,Ptpn2,Bcl6,Il10,Ifna6,Ifnb1,Ifna5,Pou2f2,Malt1,Itga4,Hhex,Plcl2,Clcf1,Vcam1,Notch2,Ifna1,Ifna2 |
| 1.272e-04 | -8.97 | development of primary sexual characteristics | biological process | GO:0045137 | 204 | 29 | 20694 | 1406 |
Serpine1,Inhba,Nupr1,Ccnd1,Ahr,Icam1,Crkl,Fndc3a,Gja1,Itgav,Hmga2,Tiparp,Arid5b,Insl6,Sirt1,Kitl,Stat5a,Nos2,Serpinb6b,Atm,Cited2,Kdr,Arid4a,Dach1,Pla2g4a,H3f3b,Angpt1,Bcl2l11,Src |
| 1.276e-04 | -8.97 | MAP kinase activation in TLR cascade | REACTOME pathways | R-MMU-450294 | 59 | 15 | 8608 | 757 |
Tab2,Fos,Nfkb1,Ripk2,Map2k4,Ikbkg,Nod2,Jun,Dusp6,Dusp4,Ppp2r1b,Nod1,Map3k8,Irak2,Mapkapk2 |
| 1.277e-04 | -8.97 | PDGF_UP.V1_UP | MSigDB lists | PDGF_UP.V1_UP | 133 | 24 | 15632 | 1249 |
Ifnar1,Ezr,Ets2,Gpsm2,Fos,Hspa2,Egr1,Atf3,Slco3a1,Slc30a1,Gng11,Traf5,Pfkfb3,Ccne1,Rnf14,Slc7a5,Ddit4,Inhba,Dnaja2,Dusp5,Egr3,Rnf19b,Cldnd1,Cdkn1a |
| 1.277e-04 | -8.97 | GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_DN | 192 | 31 | 15632 | 1249 |
Prdx1,Plagl2,Tpx2,Pttg1,Pnp2,Irf4,Phgdh,Psma6,Dusp4,Srm,Cst7,Hsph1,Tnf,Eno1,Trip10,Cyfip1,Psmb9,Gcnt2,Nfil3,Pgk1,Ldha,Hmgcs1,Sap30,Stx11,Eef1e1,Wars,Rnf14,Ccl5,Eno2,Rgl1,Tnfsf14 |
| 1.277e-04 | -8.97 | GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_UP | MSigDB lists | GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_UP | 192 | 31 | 15632 | 1249 |
Cnn3,H2-Aa,Vasp,Jarid2,Eif4g2,Irf8,Lgals9,Ifit3,Fubp1,Tax1bp1,Tnip1,Ifit3b,Adrb2,Mcm6,Gpd2,Rab21,Tbc1d1,Kdm5b,Hdac1,Parp8,Nfkbia,Bcl6,Ciita,Gys1,Pbx1,Mark2,Rab3ip,Slc30a4,Hhex,Ier2,Sell |
| 1.285e-04 | -8.96 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP | 21 | 8 | 15632 | 1249 |
Ch25h,Dusp6,Uchl1,Gdf15,Arg2,Csf1,Phlda1,Ppfibp1 |
| 1.285e-04 | -8.96 | CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP | MSigDB lists | CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP | 21 | 8 | 15632 | 1249 |
Hspa2,Myc,Mthfd2,Acsl1,Fosb,Junb,Hsph1,Cd55 |
| 1.285e-04 | -8.96 | JEON_SMAD6_TARGETS_UP | MSigDB lists | JEON_SMAD6_TARGETS_UP | 21 | 8 | 15632 | 1249 |
Csf1,Thbs1,Fas,Psmb8,Filip1l,Trib1,Serpine1,Jun |
| 1.285e-04 | -8.96 | BIOCARTA_IL12_PATHWAY | MSigDB lists | BIOCARTA_IL12_PATHWAY | 21 | 8 | 15632 | 1249 |
Jak2,Tyk2,Stat4,Etv5,Il12rb1,Il12b,Jun,Il18 |
| 1.289e-04 | -8.96 | cellular calcium ion homeostasis | biological process | GO:0006874 | 462 | 53 | 20694 | 1406 |
Fpr1,Ednrb,Htr2a,Bnip3,Ccr3,Ptgir,Edn1,Ccrl2,Cd40,Atp13a1,Cxcl2,Ccl5,Ccl2,Gpr35,Adrb2,Slc30a1,Ccr1,Pml,Cx3cr1,Kdr,Cmklr1,Ptger4,Atp2b4,Ccl3,P2ry2,Cx3cl1,Cxcl1,Cacna1d,Swap70,Il1b,Grina,Jak2,Gja1,Itgav,Htr2b,Itpr1,Marcksl1,Prkce,Gpr18,Cxcl3,Cav1,Cacnb3,Cd38,Xcr1,Fpr2,Hap1,Cxcl10,1600014C10Rik,Tmem178,Ero1l,Gna15,Lpar1,Rmdn3 |
| 1.290e-04 | -8.96 | PID_IL12_STAT4_PATHWAY | MSigDB lists | PID_IL12_STAT4_PATHWAY | 32 | 10 | 15632 | 1249 |
Il18rap,Stat4,Etv5,Cd80,Stat3,Jun,Il18,Cd86,Fos,Irf1 |
| 1.290e-04 | -8.96 | GO_PEPTIDE_ANTIGEN_BINDING | MSigDB lists | GO_PEPTIDE_ANTIGEN_BINDING | 32 | 10 | 15632 | 1249 |
H2-Ab1,H2-Q7,H2-Eb1,H2-Q4,Slc7a8,H2-Q6,Slc7a5,H2-Aa,Tap1,Tapbp |
| 1.290e-04 | -8.96 | GO_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION | 32 | 10 | 15632 | 1249 |
Casp3,Icosl,Il12rb1,Ripk3,Tnfsf4,Cd274,Prnp,Cd86,Il12b,Il18 |
| 1.290e-04 | -8.96 | FARDIN_HYPOXIA_11 | MSigDB lists | FARDIN_HYPOXIA_11 | 32 | 10 | 15632 | 1249 |
Ak4,P4ha2,Tpi1,Fam162a,Igf1r,Pgk1,Egln3,Bnip3,Ddit4,Tnip1 |
| 1.290e-04 | -8.96 | PID_HIF2PATHWAY | MSigDB lists | PID_HIF2PATHWAY | 32 | 10 | 15632 | 1249 |
Serpine1,Cited2,Slc2a1,Flt1,Sirt1,Pgk1,Egln3,Adora2a,Kdr,Mmp14 |
| 1.292e-04 | -8.95 | GO_GROWTH_FACTOR_RECEPTOR_BINDING | MSigDB lists | GO_GROWTH_FACTOR_RECEPTOR_BINDING | 125 | 23 | 15632 | 1249 |
Vegfc,Il1b,Jak2,Il1rn,Arf4,Lyn,Il12b,Tlr9,Ptprj,Itga5,Csf3,Snx2,Il12rb1,Pdgfb,Plscr1,Flrt2,Il10,Pdgfrb,Pdgfc,Il1a,Il6,Src,Flrt3 |
| 1.293e-04 | -8.95 | KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY | MSigDB lists | KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY | 117 | 22 | 15632 | 1249 |
Ifna5,Ifnb1,Casp3,Ifna6,Itgal,H2-Q6,Lcp2,Map2k1,Fcgr4,Tnf,H2-Q4,Syk,Ifnar1,Pik3r5,Ifna2,Ifna1,Tnfsf10,Icam1,Pik3cd,H2-Q7,Fas,Rac3 |
| 1.297e-04 | -8.95 | GO_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING | MSigDB lists | GO_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING | 38 | 11 | 15632 | 1249 |
Nod2,Tnfsf15,Nod1,Traf2,Uaca,Tlr6,Malt1,Eif2ak2,Ezr,Tlr3,Tnf |
| 1.297e-04 | -8.95 | GO_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | 38 | 11 | 15632 | 1249 |
Cd274,Il10,Axl,Nfkbil1,Ptger4,Zc3h12a,Errfi1,Irak3,Tnfaip3,Cd34,Tspo |
| 1.297e-04 | -8.95 | BIOCARTA_IL2RB_PATHWAY | MSigDB lists | BIOCARTA_IL2RB_PATHWAY | 38 | 11 | 15632 | 1249 |
Myc,Nmi,Syk,Stat5a,Fos,Cflar,Socs3,Fas,Crkl,Il2rg,Socs1 |
| 1.297e-04 | -8.95 | ONO_AML1_TARGETS_DN | MSigDB lists | ONO_AML1_TARGETS_DN | 38 | 11 | 15632 | 1249 |
Slfn4,Il10,Casp4,Ccl5,Irf4,Tnfsf8,Il4ra,Sell,Socs3,Rbl1,Slfn3 |
| 1.301e-04 | -8.95 | GSE7219_WT_VS_NIK_NFKB2_KO_DC_DN | MSigDB lists | GSE7219_WT_VS_NIK_NFKB2_KO_DC_DN | 158 | 27 | 15632 | 1249 |
Fcgr2b,Tnfsf8,Arhgap26,B3gnt5,Klf3,Spn,Pik3r5,Usp53,Cd302,Traf5,Atp11b,Itga4,Sell,Pigv,Tlr1,Pdss1,Smpdl3b,Dgka,Rap1gap2,Il18rap,Plek,Cldnd1,Ikbke,Arl5c,Cd55,Fcho2,Rcsd1 |
| 1.307e-04 | -8.94 | GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP | 175 | 29 | 15632 | 1249 |
Dgka,Parp12,Inpp5b,Mcm9,Dusp6,Nfkb1,Snx10,Ap3m2,Prkx,Dek,Snapc1,Rsbn1,Ripk2,Traf3ip2,Ptk2,Tlk2,Myc,Plekhf2,Parp8,Morc3,Myd88,Il15,Socs1,Trim13,Cd74,Rhoh,Ddx60,Pgs1,Hhex |
| 1.307e-04 | -8.94 | GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_UP | MSigDB lists | GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_UP | 175 | 29 | 15632 | 1249 |
Trip10,Nlrc5,Tnf,Usp53,Treml2,Fgl2,Gpr68,Scarf1,Hlx,Lrp8,Rbms2,Cacybp,Ttc9c,Tuba4a,Sh3bp4,Tdrd7,Casp2,Fzd1,Pstpip2,Trib3,Il2rg,Ptger4,Dusp5,Ppa1,Stard7,Cdkn1a,Cmpk2,Cflar,Fscn1 |
| 1.307e-04 | -8.94 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN | 175 | 29 | 15632 | 1249 |
Pik3r5,N4bp1,Dnaja1,Rhbdf2,Ppp2r5a,Dennd1b,Tnfsf8,Tra2a,Ddx60,Zfp281,Ddx58,Phip,Pigv,Psmb8,Hk1,Tor1aip1,Pid1,Jag1,Oas1a,Ptprj,Ifi35,Oas1g,Ldha,Oasl1,Map2k4,Sema4a,Il1rn,Sec24a,Armc8 |
| 1.307e-04 | -8.94 | GO_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | 175 | 29 | 15632 | 1249 |
Csf1,Csf3,Inhba,Jag1,Ccr1,Ccl5,Casp8,Irf7,Kitl,Hcls1,Pf4,Tlr3,Acvr1b,Trib1,Lyn,Il12b,Myc,Gpr68,Tnf,Nfkbia,Fos,Csf3r,Ptpn2,Jun,Fas,Lif,Ubash3b,Hif1a,Isg15 |
| 1.336e-04 | -8.92 | negative regulation of ERK1 and ERK2 cascade | biological process | GO:0070373 | 75 | 15 | 20694 | 1406 |
Rgs14,Atf3,Ezr,Phlpp1,Dusp4,Ptpn2,Lyn,Cav1,Spry2,Tnip1,Lif,Spred1,Dusp6,Dusp1,Errfi1 |
| 1.336e-04 | -8.92 | regulation of lymphocyte apoptotic process | biological process | GO:0070228 | 75 | 15 | 20694 | 1406 |
Cd74,Casp8,Il10,Cd274,Tnfsf4,Myc,Bcl2a1a,Lyn,Nfkbid,Irs2,Serpinb9,Ccl5,Ripk3,Hif1a,Arg2 |
| 1.346e-04 | -8.91 | Cyld (CYLD lysine 63 deubiquitinase) | protein interactions | 74256 | 18 | 8 | 7778 | 753 |
Fos,Stat3,Rnf31,Ripk2,Ikbkg,Casp8,Sqstm1,Jun |
| 1.352e-04 | -8.91 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | 624 | 76 | 15632 | 1249 |
Tspan3,B4galt4,Cited2,Slc44a1,Rin2,Cpd,Pde5a,Dusp4,Nek6,Tmtc2,Sgms2,Kat2b,Rtp4,Dtwd1,Dmxl2,Ahr,Clic5,Lcn2,Slpi,Alas1,Ampd3,Etv6,Dram1,Etnk1,Cpeb4,Casp7,Dyrk2,Il13ra1,C3,Ell2,Rnf145,Lyn,Sh3bgrl2,Gfpt1,Gbp2b,Tnfaip2,Idi1,Tax1bp1,Tmem123,Ppfibp2,Slc16a3,Mtus1,Tank,Tpst1,Sat1,Cp,Rffl,Ly75,Arhgap26,Malt1,Mthfr,Csrnp1,Lif,Crim1,Cd164,Nampt,Rgl1,Dusp6,Tshz1,Gdf15,Fzd5,Vps54,Wdfy1,Tnfsf15,St3gal1,Cd55,Ptprj,Pcgf5,Slc31a1,Rcan1,Lox,Sec24a,Lrp11,Inpp1,Igf2bp2,Ppp2r2a |
| 1.354e-04 | -8.91 | DELACROIX_RAR_BOUND_ES | MSigDB lists | DELACROIX_RAR_BOUND_ES | 415 | 55 | 15632 | 1249 |
Junb,Gch1,Gja1,Klf2,Pdgfrb,Med21,Rab10,Tmeff1,Oas2,Kdm6b,Slamf8,Gca,Dusp1,Lipe,Src,Itpr1,Ntng2,Rhoq,Ccnd1,Rbpms,Aebp2,Mdm2,Gsr,Plk3,Ier2,Upp1,Agtrap,Ppp1r15b,Ptch1,Ksr1,Spen,Slc39a14,Stat4,Hivep3,Itga5,Socs3,Rab20,Arf4,Ppp1r14b,Cited2,Rhof,Spry2,Pdpn,Cox17,S1pr2,Rin2,Dusp4,Gadd45g,Atf3,St3gal3,Pim3,Foxp4,Spred1,Enpp4,Atp11b |
| 1.356e-04 | -8.91 | GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_DN | 150 | 26 | 15632 | 1249 |
Itgav,Cst7,Myc,Dtnb,Tpx2,Arrdc4,Klf8,Cd80,Ccne1,Csrp1,Asns,Irf8,Pou2f2,Ppp2r3a,Wars,Ccrl2,Cd200,Larp1,Hmgcs1,Ptger4,Endod1,Irf1,Kcna3,Trib1,Rcn1,Dusp16 |
| 1.356e-04 | -8.91 | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | 150 | 26 | 15632 | 1249 |
Vcan,Ccnd1,Myc,Tnc,Bnip3,Hspa1a,Slc2a1,Ass1,Tap1,Ccnd2,Tpi1,Egln3,Hk2,Piezo1,Ddit4,Plk2,Higd1a,Lnpep,P4ha1,Cdkn1a,Pgk1,Pfkl,Fam162a,Itga9,Dusp5,Ldha |
| 1.362e-04 | -8.90 | GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_UP | MSigDB lists | GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_UP | 184 | 30 | 15632 | 1249 |
Cst7,Agrn,Arhgef3,Cyfip1,Phlpp1,Rab19,Zfp281,Hif1a,Gbp3,Sav1,Nod1,Cd80,Slc4a7,Cd274,Hopx,Vps54,Casp4,Gbp7,Reps1,Phlda1,Plscr1,Tdrd7,Stx6,Ebi3,Kif5c,Nsmaf,Ttc39b,Dek,Rgs1,Col27a1 |
| 1.362e-04 | -8.90 | GSE29949_MICROGLIA_VS_DC_BRAIN_UP | MSigDB lists | GSE29949_MICROGLIA_VS_DC_BRAIN_UP | 184 | 30 | 15632 | 1249 |
Ell2,Map2k4,Acsl1,Adam19,H3f3b,Cdkn1a,Junb,Tuba4a,Lcp2,Rel,Gem,Ddit4,Phlpp2,Slc7a5,Ier2,Atf3,Col18a1,Lif,Ccnd2,Prdx1,Sla,Gys1,Olr1,Mdfic,Nr4a1,Jun,Minpp1,Il6,Myc,Gadd45g |
| 1.362e-04 | -8.90 | KYNG_DNA_DAMAGE_DN | MSigDB lists | KYNG_DNA_DAMAGE_DN | 184 | 30 | 15632 | 1249 |
Cycs,Itgb8,Ccnd1,Rin2,Dnaja1,Tcf4,Myd88,Trp53i11,Sgcb,Pbx1,Daxx,Rbl1,Irf2,Egr1,Nrp2,H2-Aa,Cd69,Slc31a2,Hk1,Itgal,Lcn2,Cxcl1,Serpinb2,Inpp1,Esd,Glrx,Ptger4,Ppa1,Lox,Gpd2 |
| 1.362e-04 | -8.90 | GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | MSigDB lists | GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | 184 | 30 | 15632 | 1249 |
Sipa1l1,Daam1,Marco,Tnfrsf1b,Gch1,Zc3h7a,Zeb1,Spata5l1,Denr,Smc5,Dtx2,Cpeb4,Pkp4,Slfn9,Gtpbp2,Birc2,Rnf114,Hsph1,Gsdmd,Aebp2,Cox17,Ppp2r5a,Ikzf1,Slfn8,Il4ra,Ifih1,Kat2b,Ddx58,Rhoh,Tspo |
| 1.362e-04 | -8.90 | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_DN | MSigDB lists | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_DN | 184 | 30 | 15632 | 1249 |
Nlrc5,Cst7,Gpr18,Ttc39c,Cish,Lrch3,Atf3,Mapkapk2,Prnp,Fam133b,Sgk3,Sav1,Klf7,Crim1,Eno2,Nfkb1,Jdp2,Dcun1d3,Mov10,Ksr1,Procr,Bst1,Ppp2r3a,Tdrd7,Pik3cd,Nr4a3,Mthfd2,Znrf1,Chd9,Cd300lf |
| 1.362e-04 | -8.90 | CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | MSigDB lists | CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | 94 | 19 | 15632 | 1249 |
Cenpe,Nfkbia,Dusp1,Gja1,Fos,Ppp1r15a,Bcl6,Fosb,Jun,Il6,Vcan,Ier2,Nupr1,Pim2,Tgfbi,Pttg1,Tpx2,Ier3,Fscn1 |
| 1.362e-04 | -8.90 | CHEN_LIVER_METABOLISM_QTL_CIS | MSigDB lists | CHEN_LIVER_METABOLISM_QTL_CIS | 94 | 19 | 15632 | 1249 |
Ifi207,Hsd17b7,Ifi204,Kmo,F11r,Slc30a1,Ifi214,Ifi203,Fcgr2b,Ifi211,Ifi208,Lad1,Marco,Tor1aip1,Mndal,Ifi209,Ifi205,Igsf8,Ifi213 |
| 1.368e-04 | -8.90 | GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | MSigDB lists | GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | 51 | 13 | 15632 | 1249 |
Serpine1,Casp8,Traf2,Rffl,Hmox1,Fas,Atf3,Icam1,Tnfsf10,Thbs1,Rnf34,Cflar,Tnfaip3 |
| 1.368e-04 | -8.90 | GO_ALPHA_BETA_T_CELL_ACTIVATION | MSigDB lists | GO_ALPHA_BETA_T_CELL_ACTIVATION | 51 | 13 | 15632 | 1249 |
Irf1,Il12b,Sema4a,Tnfsf4,Ptger4,Relb,Batf,Il15,Syk,Rsad2,Irf4,Il6,Tnfsf8 |
| 1.368e-04 | -8.90 | GO_NAD_METABOLIC_PROCESS | MSigDB lists | GO_NAD_METABOLIC_PROCESS | 51 | 13 | 15632 | 1249 |
Pnp2,Hk2,Hk1,Nampt,Eno2,Eno1,Pfkfb3,Pgk1,Pfkl,Hk3,Ldha,Tpi1,Kmo |
| 1.370e-04 | -8.90 | WWE | prosite domains | PS50918 | 12 | 6 | 13278 | 1037 |
Dtx2,Tiparp,Parp12,Zc3hav1,Parp14,Parp11 |
| 1.380e-04 | -8.89 | BENPORATH_SOX2_TARGETS | MSigDB lists | BENPORATH_SOX2_TARGETS | 655 | 79 | 15632 | 1249 |
Prpf38a,Olfml3,Notch1,Crim1,Smg7,Bmp2,Sgk3,Sav1,Zfp281,Hhex,Rbpms,Errfi1,Ccnd1,Pnp2,Rnf24,Sat1,Stat3,Tnc,Ifi205,Ifi209,Txnrd1,Ifi213,Bambi,Clic4,Snapc1,Spire1,Arid5b,Hmox1,Vasp,Ppp2r3a,Fzd1,Inhba,Slc7a5,Ifi208,Sap30,Rrs1,Ppp1r15a,Dusp6,Gja1,Hsd17b12,Jarid2,Cdyl,Tle3,Spred1,Ifi207,Adar,Prdx1,Ifi214,Nkiras1,Prnp,Usp25,Atf3,Gadd45g,Tra2a,Vcan,Ap3b1,Slc44a1,Pdpn,Ptpn2,Slc7a11,H3f3b,Tnfaip2,Tmem123,Kdr,Ppp2r1b,Arf4,Ifi204,Kpna3,Egr3,Egln3,Ifi203,Rtn2,Ifi211,Bcl9,Mndal,Rnf31,Rnf14,Eif4g2,Abtb2 |
| 1.381e-04 | -8.89 | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN | 167 | 28 | 15632 | 1249 |
Rasgrp1,Lmo4,Samsn1,Cd86,Daam1,Tor3a,Eno2,Tfec,Ralgds,Cd82,Cflar,Ppa1,Ebi3,Dock10,Dennd1b,Ptpn2,Psmb9,Sp140,Ehd1,Mvp,Tle3,Atp2b4,Gclc,Isg15,Ccnd2,Tpi1,Rars,Aim2 |
| 1.381e-04 | -8.89 | GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_DN | MSigDB lists | GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_DN | 167 | 28 | 15632 | 1249 |
Nfkb1,Tnfrsf1b,Ccl5,Junb,St3gal5,Nrp2,Trim21,Btg2,Dcp1a,Hat1,G3bp2,Etnk1,Cflar,Cmklr1,Cst7,Bcl2l11,Aftph,Micall2,Stat3,Irf4,Nr3c1,Mdm2,Rhoh,Aim2,Ifih1,Pfkfb3,Ppfibp1,Notch1 |
| 1.422e-04 | -8.86 | RADMACHER_AML_PROGNOSIS | MSigDB lists | RADMACHER_AML_PROGNOSIS | 72 | 16 | 15632 | 1249 |
Vasn,Isg20,Cnn3,Nfkbib,Lcn2,Dmwd,Tcf4,Slc2a1,Ezr,Nfkb1,Agrn,Gypc,Angpt1,Pmepa1,Cdc42ep4,Endod1 |
| 1.424e-04 | -8.86 | GO_AMINOGLYCAN_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_AMINOGLYCAN_BIOSYNTHETIC_PROCESS | 102 | 20 | 15632 | 1249 |
Vcan,Chst11,Sdc2,Ext1,B4galt4,Dse,Pdgfrb,Abcc5,Agrn,Il1b,Angpt1,Sdc4,Extl2,Ust,Gpc1,Gcnt2,Sdc1,St3gal6,St3gal1,St3gal3 |
| 1.436e-04 | -8.85 | IG_LIKE | prosite domains | PS50835 | 456 | 58 | 13278 | 1037 |
Gm5150,H2-Q6,Malt1,Cd83,Sema4c,Tapbp,Trem1,Slamf9,Cd200,Slamf8,H2-Q4,Icosl,H2-Ab1,Treml2,Siglece,A530064D06Rik,Il18rap,Cd274,Flt1,H2-Aa,Sema3c,H2-T10,Il12b,Vcan,H2-Q7,B430306N03Rik,Cd80,Fcgr4,Kdr,Mfap3l,F11r,Igsf6,Vcam1,Palld,Slamf7,Tarm1,Igsf8,Axl,H2-M2,Tapbpl,Igsf9,Clmp,Fcgr2b,Il18bp,Milr1,Cd200r4,Spaca6,Nectin2,Icam1,Treml4,H2-T24,H2-Eb1,Pdgfrb,Fcgr1,Nectin4,Pvr,H2-T22,Cd86 |
| 1.436e-04 | -8.85 | Spinal Cord Injury | WikiPathways | WP2432 | 98 | 24 | 4813 | 540 |
Rhoc,Casp3,Il6,Il1b,Mmp9,Gja1,Ccnd1,Ccl2,Btg2,Cxcl10,Chst11,Zfp36,Cxcl1,Myc,Egr1,Vcan,Tnf,Nr4a1,Icam1,Fos,Cxcl2,Nos2,Fcgr2b,Il1a |
| 1.437e-04 | -8.85 | regulation of dendritic cell antigen processing and presentation | biological process | GO:0002604 | 9 | 5 | 20694 | 1406 |
Cd74,Nod1,Nod2,Thbs1,Fgl2 |
| 1.437e-04 | -8.85 | Fc-gamma receptor signaling pathway | biological process | GO:0038094 | 9 | 5 | 20694 | 1406 |
Fcgr1,Clec4e,Fcgr4,Fcgr2b,Clec4d |
| 1.440e-04 | -8.85 | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | MSigDB lists | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | 311 | 44 | 15632 | 1249 |
Nqo1,Bcl2a1d,Cpd,Mid1,Cers6,Ifrd1,Myc,Peli1,Nat2,Fut8,D1Ertd622e,Phgdh,Bcl2a1b,Sod2,Ccl12,Myo10,Slc16a1,Pbx1,Tpx2,Cx3cl1,Rnd1,Prnp,Pttg1,Mcm10,Nck1,Evl,Pdss1,Lmo4,Sema3c,Marco,Gdf15,Ccne1,Slc7a8,Dach1,Nfil3,Igf2bp2,Clic4,Tmem123,Prkx,Asf1a,Bcl2a1a,Lyn,Mthfd2,Slc43a3 |
| 1.442e-04 | -8.84 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP | 58 | 14 | 15632 | 1249 |
Hhex,Marcksl1,Arrdc4,Sgcb,Plau,Plat,Sqstm1,Sod2,Asns,Dmwd,Hmga1,Csf1,Phlda1,Cd69 |
| 1.448e-04 | -8.84 | GSE3982_EOSINOPHIL_VS_MAST_CELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAST_CELL_UP | 176 | 29 | 15632 | 1249 |
Pim2,Oasl1,Fpr1,Mmp25,Tax1bp1,Notch2,Jak2,Pdk3,Casp8,Itgal,Samsn1,Tnfsf14,Cysltr2,Etv6,Syne2,Mthfr,Cdkn2d,Zfp281,Sla,Angpt1,Hk3,Parp8,Cnn2,P2ry13,Dusp8,Peli1,Rnf24,Rsad2,4932438A13Rik |
| 1.448e-04 | -8.84 | GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_UP | MSigDB lists | GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_UP | 176 | 29 | 15632 | 1249 |
Il15,Sav1,Zfp281,Stat2,Cd74,Slc30a4,Itga4,Rnf24,Zyx,Birc2,Rab32,Rnf114,N4bp1,Psip1,Stard7,Vegfc,Acp2,Ms4a6d,Adrb2,Map3k8,Rictor,Il12rb1,Pde7b,Il18rap,Flnb,Cd86,Mier3,Clic5,Card6 |
| 1.448e-04 | -8.84 | GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_DN | 176 | 29 | 15632 | 1249 |
Atf3,Daxx,Olfml3,Sgk3,Tmem184b,Ifit1bl1,Cx3cr1,Ifit2,Itgav,Ccnd1,Rsad2,Samd9l,Sat1,Ifit3b,Hmgcs1,Atp10a,Dck,H3f3b,Rgs1,Slc29a3,Cd300lf,Fam20c,Mov10,Irf8,Ifit3,Ifit1bl2,Mmd,Eya4,Ube2l6 |
| 1.449e-04 | -8.84 | positive regulation of mitotic cell cycle | biological process | GO:0045931 | 166 | 25 | 20694 | 1406 |
Il1b,Mdm2,Pdgfrb,Rgcc,Pbx1,Ccnd1,Igf1r,Sphk1,Ankrd17,Hspa2,Ube2e2,Edn1,Phip,Ccne1,Met,Asns,Stat5a,Il1a,Tmod3,Tnf,Smc5,Pdgfb,Mecp2,Ccnd2,Cenpe |
| 1.452e-04 | -8.84 | positive regulation of proteolysis involved in cellular protein catabolic process | biological process | GO:1903052 | 119 | 20 | 20694 | 1406 |
Rnf14,Nupr1,Plk3,Ankib1,Psmd10,Trib1,Dnajb2,Hspa1a,Tmem67,Ctsc,Gclc,Trib3,Cop1,Rnf19b,Ptk2,Rnf139,Hspa1b,Plk2,Mdm2,Rnf19a |
| 1.453e-04 | -8.84 | GO_KINASE_ACTIVITY | MSigDB lists | GO_KINASE_ACTIVITY | 780 | 91 | 15632 | 1249 |
Fam20c,Kdr,Pfkl,Igf1r,Itpkc,Dyrk2,Dck,Etnk1,Pik3cd,Acvr1b,Ksr1,Akt3,Met,Ccne1,Pdk3,Pfkfb3,Ciita,Mark2,Mapkapk2,Sgms2,Prkce,Ccl12,Pik3r5,Map3k6,Flt1,Prkx,Cmpk2,Scyl2,Pim1,Ak4,Pdgfb,Tyk2,Dgka,Hk2,Map4k4,Pik3r6,Plk2,Cd86,Hck,Crim1,Ripk3,Fgr,Sphk1,Mlkl,Stk40,Acvrl1,Acvr1,Ccnd1,Src,Axl,Jak2,Cdkn1a,Vrk2,Pim2,Dgkh,Ptk2,Tlr9,Lyn,Map2k4,Trib1,Mmd,Hk1,Atm,Sik3,Cd80,Pim3,Hk3,Nek6,Pikfyve,Cdk5r1,Papss2,Irs2,Syk,Sqstm1,Eif2ak2,Irak2,Kitl,Ikbke,Pgk1,Ripk2,Map3k8,Trib3,Nrp2,Ccl5,Pdgfrb,Map2k1,Sgk3,Irak3,Plk3,Tlk2,Stat5a |
| 1.474e-04 | -8.82 | GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN | MSigDB lists | GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN | 8 | 5 | 15632 | 1249 |
Hck,Fosb,Dusp1,S100a8,Il6 |
| 1.483e-04 | -8.82 | response to antibiotic | biological process | GO:0046677 | 278 | 36 | 20694 | 1406 |
Bnip3,Mdm2,Zc3h12a,Pdgfrb,Nqo1,Sirt1,Hp,Axl,Kdm6b,Sphk1,Larp1,Igf1r,Jak2,Casp3,Tnfaip3,Egr1,Ahr,Nr4a3,Ripk3,Prkce,Hmox1,Timeless,Tlr9,Gk,Src,Lcn2,Casp8,Ppp1r15b,Pla2g4a,Il6,Pdgfb,Hif1a,Ciita,Sod2,Ccl7,Daxx |
| 1.485e-04 | -8.81 | SASSON_RESPONSE_TO_FORSKOLIN_UP | MSigDB lists | SASSON_RESPONSE_TO_FORSKOLIN_UP | 87 | 18 | 15632 | 1249 |
Cdc42ep4,Jmjd6,Upp1,Col18a1,Cd55,Acp2,Pgk1,Tnfaip3,Stip1,Prkx,Cflar,Map2k1,Itpr1,Acpp,Ezr,P4ha2,Dusp1,Hk2 |
| 1.493e-04 | -8.81 | Fc gamma R-mediated phagocytosis | KEGG pathways | ko04666 | 85 | 19 | 7931 | 713 |
Plpp3,Vasp,Fcgr1,Map2k1,Pik3cd,Crkl,Marcks,Syk,Hck,Lyn,Fcgr2b,Myo10,Pla2g4a,Sphk1,Marcksl1,Plpp1,Asap3,Prkce,Akt3 |
| 1.493e-04 | -8.81 | Fc gamma R-mediated phagocytosis | KEGG pathways | mmu04666 | 85 | 19 | 7931 | 713 |
Fcgr2b,Hck,Lyn,Syk,Marcks,Crkl,Pik3cd,Map2k1,Fcgr1,Vasp,Plpp3,Akt3,Prkce,Asap3,Plpp1,Marcksl1,Sphk1,Pla2g4a,Myo10 |
| 1.504e-04 | -8.80 | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_UP | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_UP | 185 | 30 | 15632 | 1249 |
Rab19,Rnf135,Ube2e1,Psme1,Mapkapk2,Hk3,Rnd3,Cd40,Tpst1,Itgav,Casp3,Rhoq,Trib1,Frmd4a,Cxcl10,Casp7,Il13ra1,Il1b,Armc8,Notch2,Dek,Gfpt1,Gca,Cldnd1,Adap2,Slc31a2,Smpdl3b,Parp12,Met,Flnb |
| 1.504e-04 | -8.80 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_DN | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_DN | 185 | 30 | 15632 | 1249 |
Atp11b,Crim1,Klf7,Rras2,Dse,Acpp,Trmt1l,Insl6,Ddhd1,Dock10,Aebp2,Cd200r4,Arhgap26,Dusp2,Phgdh,St7,Sema4a,Frmd4a,Irf1,Crkl,Hsd17b7,Slc37a3,Agpat4,Ccl4,Pdgfrb,Tnfrsf1b,Rap1gap2,Egln3,Trim14,Wdr59 |
| 1.504e-04 | -8.80 | GSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_DN | MSigDB lists | GSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_DN | 185 | 30 | 15632 | 1249 |
Clic4,Adam19,Trafd1,Naa25,Ppa1,Rcan1,Ifi204,Spire1,Ifi211,Psme2,Ifi208,Stat4,Ifi203,Gch1,Mndal,Golga3,Ifi207,Mcoln2,Prnp,Plagl1,Arl4a,Ifi214,Gbp3,Top3a,Nod2,Parp9,Ifi213,Itpr1,Ifi209,Ifi205 |
| 1.507e-04 | -8.80 | protein dephosphorylation | biological process | GO:0006470 | 186 | 27 | 20694 | 1406 |
Dusp14,Dusp16,Plpp1,Ppp2r5a,Ppm1l,Dusp4,Ptpn2,Ppp1r15a,Mtmr14,Dusp28,Ppp4r2,Ppp2r3a,Acp2,Ubash3b,Dusp1,Phlpp2,Dusp6,Ppm1k,Dusp8,Phlpp1,Nck1,Dusp5,Ppp2r2a,Dusp2,Ppp1r15b,Ptprj,Eya4 |
| 1.508e-04 | -8.80 | protein modification by small protein conjugation | biological process | GO:0032446 | 499 | 56 | 20694 | 1406 |
Trim36,Rffl,Pcgf5,Trim12a,Rnf135,Dcun1d3,Herc6,Rnf34,Znrf3,Egr2,Birc3,Trim56,Uba7,Bfar,Med21,Arrdc4,Rnf19a,Klhl25,Ube2f,Socs7,Ube2e2,Ifih1,Trim21,Birc2,Cop1,Rnf19b,Cnot4,Rnf31,Dtx3l,Malt1,Ube2e1,Mul1,Rnf14,Ankib1,Traf2,Ubr4,Trim12c,Peli1,Sde2,Fbxo4,Tnfaip3,Trim30a,Keap1,Znrf1,Vcpip1,Bcor,Crbn,Trim13,Ranbp2,Dtx2,Isg15,Mdm2,Arel1,Spsb1,Rnf139,Sirt1 |
| 1.517e-04 | -8.79 | positive regulation of ion transport | biological process | GO:0043270 | 321 | 40 | 20694 | 1406 |
Pdgfrb,Kmo,Il1b,Akt3,Fabp3,Acsl5,Itpr1,Edn1,Homer1,Hspa2,Ccl5,Serpine1,Cav1,Ccl2,Slc9a1,Cox17,Adrb2,Nr3c1,Cacnb3,Ccl12,Glrx,Hap1,Kcnj2,Ccr1,Mllt6,Cxcl10,Ccl4,Stxbp1,Ptafr,Scn1b,Abcb1a,Pdgfb,Cx3cl1,P2ry2,Adora2a,Il1a,Tspo,P2ry12,Cacna1d,Cxcl1 |
| 1.533e-04 | -8.78 | Ig/MHC_CS | interpro domains | IPR003006 | 57 | 13 | 19984 | 1430 |
H2-T22,H2-Aa,H2-T24,H2-M2,H2-Eb1,Tapbp,Siglece,H2-T10,H2-Ab1,H2-Q7,H2-Q4,H2-Q6,Tapbpl |
| 1.533e-04 | -8.78 | GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | MSigDB lists | GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | 168 | 28 | 15632 | 1249 |
Nfil3,Max,Mmp9,Gpr132,Pdlim7,Tyk2,Ifit1bl2,Gem,Gnb4,Zc3hav1,Rhoc,Pttg1,Fpr2,Xrn1,Arrdc4,Dmxl2,Slc15a3,Gpr68,Phactr4,Tapbp,Ifit1bl1,Cx3cr1,Homer1,Znfx1,Arid5a,Dse,Traf2,Gpsm2 |
| 1.543e-04 | -8.78 | CLEC7A (Dectin-1) signaling | REACTOME pathways | R-MMU-5607764 | 94 | 20 | 8608 | 757 |
Psmb9,Nfkb2,Nfkbia,Psmb6,Syk,Psme1,Il1b,Psmb8,Nfkb1,Psmb10,Casp8,Ikbkg,Psme2,Psma6,Src,Tab2,Malt1,Relb,Psmd10,Psme2b |
| 1.543e-04 | -8.78 | negative regulation of muscle contraction | biological process | GO:0045932 | 31 | 9 | 20694 | 1406 |
Dock4,Ptgs2,Calcrl,Adora2b,Arg2,Zc3h12a,Adrb2,Ptger4,Pde5a |
| 1.544e-04 | -8.78 | GO_RESPONSE_TO_ANTIBIOTIC | MSigDB lists | GO_RESPONSE_TO_ANTIBIOTIC | 45 | 12 | 15632 | 1249 |
Mdm2,Il6,Rab10,Slc9a1,Casp3,Pla2g4a,Casp8,Ppp1r15a,Ccl12,Il1b,Jak2,Ciita |
| 1.544e-04 | -8.78 | KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION | MSigDB lists | KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION | 45 | 12 | 15632 | 1249 |
Icosl,Il6,H2-Aa,Cd86,Il10,Cd40,H2-Eb1,Il15ra,Il15,Cd80,Itga4,H2-Ab1 |
| 1.544e-04 | -8.78 | GO_ADP_METABOLIC_PROCESS | MSigDB lists | GO_ADP_METABOLIC_PROCESS | 45 | 12 | 15632 | 1249 |
Eno1,Ak4,Hk1,Ldha,Tpi1,Eno2,Pgk1,Hk2,Pfkl,Hk3,Ampd3,Pfkfb3 |
| 1.544e-04 | -8.78 | regulation of endothelial cell migration | biological process | GO:0010594 | 157 | 24 | 20694 | 1406 |
Rgcc,Hmox1,Cd40,Notch1,Akt3,Zc3h12a,Sirt1,Svbp,Ptgs2,Stat5a,Kdr,Hif1a,Mecp2,Plpp3,Spred1,Vegfc,Pdgfb,Adora2b,Sema4a,Acvrl1,Angpt1,Met,Thbs1,Plk2 |
| 1.550e-04 | -8.77 | AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D | MSigDB lists | AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D | 312 | 44 | 15632 | 1249 |
Phlpp2,Ccnj,Rgl1,Arid4a,Bambi,Ralgds,Rsbn1,Frmd4a,Nr4a3,Usp42,Phf6,Dnaja2,Fndc3a,Cers6,Zfp800,Aebp2,Mecp2,Ccnd1,Itgb8,Rab11fip1,Bcl6,Mtus1,Ddhd1,Parp8,Rhoc,Plagl2,Crim1,Ncoa7,Irf2,Ednrb,Mier3,Mfap3l,Asf1a,Mllt6,Dusp2,Tiparp,Znfx1,Bcl2l11,Trim36,Flt1,Rbl1,Kat2b,Ccnd2,Sdc1 |
| 1.551e-04 | -8.77 | TTTGCAC_MIR19A_MIR19B | MSigDB lists | TTTGCAC_MIR19A_MIR19B | 476 | 61 | 15632 | 1249 |
Elmod2,Bambi,Dcbld2,Atp10a,Rtn1,Dnaja2,Fndc3a,Spire1,Nrp2,G3bp2,Pde7b,Slc31a2,Rgl1,Gja1,Gda,Mdfic,Lif,Atp11a,Socs1,Rab21,D1Ertd622e,Mecp2,Zfp800,Ppp6r1,Itpr1,Rbbp8,Rbms1,Tnip1,Rap2c,Pmepa1,Armc8,Kpna3,Cpeb4,Sema4c,Ell2,Socs3,Rnf145,Spen,Slc9a1,St3gal5,Cd69,Mier3,Lnpep,Cep350,Pfkfb3,Slc48a1,Aff1,Chmp4b,Vcpip1,Abr,Ccnd2,Sdc1,Arrdc4,Kcnj2,Cnot4,Mllt6,Psd,Rin2,Pde5a,Scarf1,Fam43a |
| 1.559e-04 | -8.77 | GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | 12 | 6 | 15632 | 1249 |
Nlrp3,Mefv,Tnfaip3,Errfi1,Pml,Zc3h12a |
| 1.559e-04 | -8.77 | GO_POSITIVE_REGULATION_OF_MACROPHAGE_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MACROPHAGE_DIFFERENTIATION | 12 | 6 | 15632 | 1249 |
Trib1,Casp8,Pf4,Csf1,Hcls1,Lif |
| 1.559e-04 | -8.77 | BIOCARTA_ARENRF2_PATHWAY | MSigDB lists | BIOCARTA_ARENRF2_PATHWAY | 12 | 6 | 15632 | 1249 |
Fos,Mafg,Jun,Mafk,Maff,Keap1 |
| 1.559e-04 | -8.77 | NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_DN | MSigDB lists | NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_DN | 12 | 6 | 15632 | 1249 |
Casp2,Tnfaip3,Cdkn1a,Ikbke,Tnf,Stat1 |
| 1.562e-04 | -8.76 | regulation of neurotransmitter levels | biological process | GO:0001505 | 376 | 45 | 20694 | 1406 |
Stxbp1,Ptger4,Atp2b4,Hdc,Adora2a,P2ry2,Tnf,Sod2,Cacna1d,Tspo,Ppfia3,Adrb2,Slc30a1,Gch1,Il10,Cx3cr1,Klf2,Pde1b,Icam1,Tha1,Htr2a,Kmo,Klrk1,Il6,Phgdh,Nos2,Ptgs2,Cd34,Ass1,Stx11,Adora2b,Rims3,Jak2,Tlr6,Pdzd11,Sphk1,Tlr2,Prkce,Slc7a11,Cav1,Apba1,Acp5,Zc3h12a,Slc7a2,Il1b |
| 1.571e-04 | -8.76 | regulation of plasma membrane bounded cell projection organization | biological process | GO:0120035 | 770 | 79 | 20694 | 1406 |
Lyn,Cav1,Kremen1,Cdk5r1,Sphk1,Rap1gap2,Dbnl,Crkl,Itpr1,Il15ra,Gfi1,Scarf1,Mdm2,Sirt1,Mul1,Lpar1,Lrp4,Syne2,Cflar,Cyfip1,Il6,Scn1b,Lif,Hap1,Sema4a,Eif4g2,Map2k1,Rapgef2,Plk2,Map4k4,Sema3c,Cd38,Nr3c1,Prnp,Src,Cdc42ep2,Carmil1,Kat2b,Lrp8,Icam1,Nlgn2,D16Ertd472e,Ifrd1,Igf1r,Sipa1l1,Stap1,Tmem67,Sema4c,Homer1,Rhoq,Rab3ip,Mark2,Dync1i2,Ptk2,Agrn,Prag1,Fscn1,Myo10,P2ry12,Ehd1,Fzd1,Zswim4,Pdpn,Cx3cl1,P2ry2,Mecp2,Mov10,Kif3c,Cenpj,Ezr,Rab21,Sdc2,Katna1,Fcgr2b,Nck1,Evl,Ust,Cdc42ep4,Met |
| 1.576e-04 | -8.76 | GRYDER_PAX3FOXO1_ENHANCERS_KO_DOWN | MSigDB lists | GRYDER_PAX3FOXO1_ENHANCERS_KO_DOWN | 398 | 53 | 15632 | 1249 |
Dock10,Arhgap26,Errfi1,Acvr1,Itgb8,Rhoq,Stat3,Nr3c1,Tpst1,Serp1,Rbbp8,Arhgef3,Hsph1,Tnfaip3,Etv5,Pbx1,Bfar,Stx11,Wars,Nrp2,Slc7a2,Ascc3,Sipa1l1,Daam1,Csrp1,Map4k4,Dusp6,Jarid2,Gng12,Sdc2,Ass1,Psip1,Col4a2,Il4ra,Xrn1,Sdc1,Ccnd2,Bcor,Atf3,Pgs1,Met,Ube2e2,Ppp4r2,Lmo4,Pid1,Actb,Fscn1,Notch2,Rnf145,Rcn1,Socs3,Dyrk2,Etnk1 |
| 1.576e-04 | -8.76 | positive regulation of ubiquitin-dependent protein catabolic process | biological process | GO:2000060 | 93 | 17 | 20694 | 1406 |
Hspa1a,Ankib1,Psmd10,Rnf14,Plk3,Dnajb2,Trib1,Rnf139,Hspa1b,Rnf19a,Mdm2,Plk2,Gclc,Ptk2,Trib3,Cop1,Rnf19b |
| 1.582e-04 | -8.75 | Focal adhesion | KEGG pathways | ko04510 | 198 | 34 | 7931 | 713 |
Pdgfc,Igf1r,Col4a2,Flt1,Zyx,Birc3,Itga4,Ccnd1,Crkl,Vegfc,Pdgfrb,Rac3,Ppp1r12b,Met,Itga9,Map2k1,Pdgfb,Itgav,Ptk2,Akt3,Src,Tnc,Thbs1,Jun,Ccnd2,Cav1,Actb,Itga5,Birc2,Itgb8,Kdr,Flnb,Vasp,Pik3cd |
| 1.582e-04 | -8.75 | Focal adhesion | KEGG pathways | mmu04510 | 198 | 34 | 7931 | 713 |
Ppp1r12b,Itga9,Met,Map2k1,Crkl,Ccnd1,Pdgfrb,Vegfc,Rac3,Birc3,Itga4,Pdgfc,Igf1r,Zyx,Flt1,Col4a2,Flnb,Vasp,Pik3cd,Cav1,Birc2,Itga5,Actb,Itgb8,Kdr,Tnc,Ccnd2,Jun,Thbs1,Pdgfb,Itgav,Src,Akt3,Ptk2 |
| 1.592e-04 | -8.75 | DURAND_STROMA_S_UP | MSigDB lists | DURAND_STROMA_S_UP | 266 | 39 | 15632 | 1249 |
Dtx3l,Il4ra,Rtp4,Ubash3b,Calcrl,Plagl1,Ahr,Il15,Ifit1bl1,Cdyl2,Pde1b,Fut8,Tgfbi,Lpar1,Oasl1,Stat1,Ell2,Rac3,Il13ra1,St3gal1,Atp10a,Glrx,Kitl,Lrp11,Ust,Adam19,Plekha2,Pdgfrb,Ccl5,Ltbp2,Ifit1bl2,Il18rap,Fzd1,Eya4,Car13,Scn1b,Trim21,Fabp7,Ube2l6 |
| 1.597e-04 | -8.74 | KEGG_HEMATOPOIETIC_CELL_LINEAGE | MSigDB lists | KEGG_HEMATOPOIETIC_CELL_LINEAGE | 80 | 17 | 15632 | 1249 |
Csf3r,Tnf,H2-Eb1,Csf3,Il6,Csf1,Il4ra,Il1a,Itga5,Cd55,Itga4,Il1b,Cd38,Kitl,Fcgr1,Cd14,Cd34 |
| 1.597e-04 | -8.74 | SIRNA_EIF4GI_DN | MSigDB lists | SIRNA_EIF4GI_DN | 80 | 17 | 15632 | 1249 |
Slc31a1,Ripk2,Papss2,Fam111a,Slc43a3,Myd88,Rnf34,Igf2bp2,Atp2b4,Ccl12,Snx10,Hsd17b12,Vps54,Tank,Fchsd2,Trip13,Dusp4 |
| 1.602e-04 | -8.74 | regulation of cell cycle process | biological process | GO:0010564 | 581 | 63 | 20694 | 1406 |
Crlf3,Osm,Pbx1,Ccnd1,Cdk5r1,Prkce,Sphk1,Pttg1,Gpsm2,Chmp4b,Il1b,Hmga2,Mdm2,Gpr132,Ier3,Psme1,Smc5,Tmod3,Atm,Pdgfb,Nek6,Lif,Psme2,Ccnd2,Ccne1,Casp2,Plk2,Prdm9,Hspa1b,Sde2,Cdkn2d,Kat2b,Pkp4,Rgcc,Ankrd17,Hspa2,Ube2e2,Trip13,Rbl1,Igf1r,Edn1,Phip,Tmem67,Dync1h1,Parp3,Pdgfrb,Tnf,Plk3,Pdpn,Slfn1,Il1a,Tpx2,Mecp2,Dcun1d3,Atp2b4,Hspa1a,Cenpe,Cenpj,Cdkn1a,Dach1,Pml,Ccl12,Met |
| 1.602e-04 | -8.74 | amyloid-beta binding | molecular function | GO:0001540 | 59 | 13 | 20217 | 1400 |
Gsap,Prnp,Ldlr,Fcgr2b,Fpr2,Cd74,Tlr2,Lrp8,Msr1,Marco,Adrb2,Apba1,Fzd5 |
| 1.603e-04 | -8.74 | GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP | MSigDB lists | GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP | 177 | 29 | 15632 | 1249 |
Timp1,Csf3r,Tcf4,Nr4a1,Rab32,Flt1,Gadd45b,Tnf,Gypc,Slc16a3,Apobec3,Ccnd1,Isg15,Rhoc,Fcgr1,Sik3,Plek,Tnfrsf1b,Pou2f2,Fzd1,Inpp5b,Ddit4,Timeless,Rtn2,Acvr1b,Dusp5,Gng4,Cxcl1,Gcnt2 |
| 1.603e-04 | -8.74 | GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_UP | MSigDB lists | GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_UP | 177 | 29 | 15632 | 1249 |
Tifa,Ube2l6,Xaf1,Oas2,Hivep3,Ube2e2,Tuba4a,Card6,Ccr1,Rrs1,Casp8,Sp110,Cmpk2,Lrrc8c,Tagap,Mtmr14,Pdzd11,Mppe1,Ccdc86,Ifi44,Egr2,I830077J02Rik,Mlkl,Plod3,Plekhf2,Bcl6,Hk3,Ch25h,Evl |
| 1.603e-04 | -8.74 | GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_UP | MSigDB lists | GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_UP | 177 | 29 | 15632 | 1249 |
Tnks1bp1,Vcpip1,Adar,Sdc4,Rtp4,Upp1,Cpd,Pde5a,Fgl2,Cish,Gbp9,Gbp4,Gsta3,Wdr43,Osbpl3,Pcdh7,Clec5a,Mmp9,Ifi35,Naa25,Tdrd7,Jag1,Phlda1,Ascc3,Plekhg1,Tnfsf14,Ppm1k,Psd4,Dach1 |
| 1.603e-04 | -8.74 | GSE17721_POLYIC_VS_CPG_24H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_24H_BMDC_DN | 177 | 29 | 15632 | 1249 |
Lyn,Gpd2,Uchl1,Cflar,Jak2,Cav1,Slc4a7,Gja1,Car13,Rnf19a,Slc39a14,Vasp,Fabp7,Atxn7l1,Antxr1,Flnb,Slc30a4,Mapkapk2,Slc48a1,Ahsa1,Mrpl52,Spic,D16Ertd472e,Cd40,Agrn,Mecp2,Gsr,Gclm,Ccl2 |
| 1.604e-04 | -8.74 | regulation of microglial cell activation | biological process | GO:1903978 | 19 | 7 | 20694 | 1406 |
Stap1,Sphk1,Atm,Ldlr,Ctsc,Cx3cl1,Cst7 |
| 1.604e-04 | -8.74 | negative regulation of cellular senescence | biological process | GO:2000773 | 19 | 7 | 20694 | 1406 |
Hmga2,Akt3,Nampt,Sirt1,Plk2,Bcl6,Rbl1 |
| 1.604e-04 | -8.74 | positive regulation of monocyte chemotaxis | biological process | GO:0090026 | 19 | 7 | 20694 | 1406 |
Cxcl10,Ccl2,Serpine1,Fpr2,Pla2g7,Ccr1,Ccl5 |
| 1.604e-04 | -8.74 | necroptotic process | biological process | GO:0070266 | 19 | 7 | 20694 | 1406 |
Birc2,Ripk3,Fas,Tnf,Tlr3,Mlkl,Birc3 |
| 1.604e-04 | -8.74 | leukocyte tethering or rolling | biological process | GO:0050901 | 19 | 7 | 20694 | 1406 |
Vcam1,Spn,Itga4,Tnf,Sele,Cx3cr1,Sell |
| 1.604e-04 | -8.74 | G protein-coupled purinergic receptor signaling pathway | biological process | GO:0035588 | 19 | 7 | 20694 | 1406 |
Adora2a,Ptafr,P2ry2,P2ry14,Adora2b,P2ry12,P2ry13 |
| 1.604e-04 | -8.74 | regulation of lipopolysaccharide-mediated signaling pathway | biological process | GO:0031664 | 19 | 7 | 20694 | 1406 |
Acod1,Prdm1,Nfkbil1,Cx3cl1,Cd180,Trib1,Tnfaip3 |
| 1.604e-04 | -8.74 | interferon-gamma production | biological process | GO:0032609 | 19 | 7 | 20694 | 1406 |
Isg15,Il18rap,Rnf19b,Il18,Azi2,Spn,Gadd45g |
| 1.604e-04 | -8.74 | actin filament bundle assembly | biological process | GO:0051017 | 68 | 14 | 20694 | 1406 |
Zyx,Ezr,Rhoc,Rnd1,Fscn1,Swap70,Src,Myo1b,Rnd3,Spire1,Dbnl,Triobp,Marcks,Rhof |
| 1.610e-04 | -8.73 | GO_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE | 27 | 9 | 15632 | 1249 |
Clec4d,Sema4a,Il12b,Ptger4,Relb,Il6,Clec4e,Batf,Irf4 |
| 1.610e-04 | -8.73 | TRACEY_RESISTANCE_TO_IFNA2_DN | MSigDB lists | TRACEY_RESISTANCE_TO_IFNA2_DN | 27 | 9 | 15632 | 1249 |
Plat,Myc,Dnajb2,Map2k1,Ptafr,Lyn,Pttg1,Samsn1,Cav1 |
| 1.610e-04 | -8.73 | GNF2_TNFSF10 | MSigDB lists | GNF2_TNFSF10 | 27 | 9 | 15632 | 1249 |
Hck,Pilra,Igsf6,Tnfsf10,Tlr1,P2ry13,Fpr1,Csf3r,Ccr1 |
| 1.610e-04 | -8.73 | GNF2_LYN | MSigDB lists | GNF2_LYN | 27 | 9 | 15632 | 1249 |
Rnaset2b,Snx2,Sp110,Myd88,Rnaset2a,Lyn,Serp1,Sell,Syk |
| 1.610e-04 | -8.73 | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_10_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_10_PRODUCTION | 27 | 9 | 15632 | 1249 |
Tlr9,Tnfsf4,Ptger4,Il12b,Cd274,Cd34,Cd83,Irf4,Nod2 |
| 1.615e-04 | -8.73 | GO_NEGATIVE_REGULATION_OF_NEURON_DEATH | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NEURON_DEATH | 160 | 27 | 15632 | 1249 |
Gclc,Cd34,Angpt1,Chmp4b,Stxbp1,Hif1a,Il6,Stat3,Gclm,Mecp2,Ccl12,Sod2,Axl,Jun,Traf2,Clcf1,Jak2,Hmox1,Cpeb4,Nr4a3,Map2k4,Btg2,Sirt1,Csf3,Ccl5,Ikbkg,Rel |
| 1.625e-04 | -8.72 | KAYO_AGING_MUSCLE_UP | MSigDB lists | KAYO_AGING_MUSCLE_UP | 221 | 34 | 15632 | 1249 |
Scarf1,Tra2a,Fut8,Ccl12,Ezr,Flt1,Eif2ak2,Angpt1,Rbl1,Pde3b,Sgcb,Cd83,Calcrl,Etv3,Ier2,Inhba,Stxbp3,Trip13,Trim26,Csf1,Serpine1,Cnp,Asns,Ltbp2,Brd2,Pde4b,Prkar2b,Cdkn1a,Gcnt2,Hcls1,Actb,Il18,Nr4a3,Rtn1 |
| 1.627e-04 | -8.72 | Prolactin signaling pathway | KEGG pathways | mmu04917 | 72 | 17 | 7931 | 713 |
Socs3,Map2k1,Socs7,Pik3cd,Irf1,Jak2,Stat3,Ccnd1,Cish,Stat1,Socs1,Nfkb1,Ccnd2,Stat5a,Src,Fos,Akt3 |
| 1.627e-04 | -8.72 | Prolactin signaling pathway | KEGG pathways | ko04917 | 72 | 17 | 7931 | 713 |
Jak2,Stat3,Irf1,Ccnd1,Socs3,Socs7,Pik3cd,Map2k1,Akt3,Fos,Src,Stat5a,Nfkb1,Ccnd2,Stat1,Cish,Socs1 |
| 1.633e-04 | -8.72 | regulation of anion transport | biological process | GO:0044070 | 120 | 20 | 20694 | 1406 |
Syk,Abcb1a,Arg2,Ptafr,Stxbp1,Edn1,Irs2,P2ry2,Hk1,Adora2a,Il1a,Tnf,Nr3c1,Thbs1,Prnp,Acsl5,Fabp3,Kmo,Il1b,Il1rn |
| 1.637e-04 | -8.72 | LABBE_TARGETS_OF_TGFB1_AND_WNT3A_DN | MSigDB lists | LABBE_TARGETS_OF_TGFB1_AND_WNT3A_DN | 103 | 20 | 15632 | 1249 |
Mmp13,Wars,Spint2,Nrp2,Cp,Slc2a1,Lcn2,Plek,Pfkl,Cd164,Pgk1,Vcam1,Lipg,Gclc,Kitl,Cd14,Ldlr,Slc30a4,C3,Ldha |
| 1.646e-04 | -8.71 | leukocyte proliferation | biological process | GO:0070661 | 111 | 19 | 20694 | 1406 |
Tnfsf4,Cd180,Psmb10,Malt1,Ifna1,Itgal,Plcl2,Ifna6,Il15,Cx3cl1,Csf1,Ifnb1,Ifna4,Ripk2,Ifna5,Ifna2,Gja1,Azi2,Ebi3 |
| 1.655e-04 | -8.71 | GO_REGULATION_OF_CELL_SHAPE | MSigDB lists | GO_REGULATION_OF_CELL_SHAPE | 127 | 23 | 15632 | 1249 |
Cyfip1,Ezr,Ccl12,Pdpn,Il6,Rhoq,Ccl2,Phip,Icam1,Fgr,Hck,Myo10,Cdc42ep2,Brwd3,Rhou,Lpar1,Sema4a,Cdc42ep4,Atp10a,Ptk2,Vrk2,Bambi,Kdr |
| 1.656e-04 | -8.71 | antigen processing and presentation of endogenous peptide antigen | biological process | GO:0002483 | 38 | 10 | 20694 | 1406 |
H2-T22,H2-Q6,Tapbp,Tap1,Tap2,H2-Q7,H2-Q4,H2-T24,H2-M2,H2-T10 |
| 1.656e-04 | -8.71 | positive regulation of lymphocyte migration | biological process | GO:2000403 | 38 | 10 | 20694 | 1406 |
Ccl5,Tnfsf14,Tnfsf4,Lgals9,Tnfrsf14,Cxcl10,Ccl4,Cxcl14,Itga4,Spn |
| 1.656e-04 | -8.71 | antigen processing and presentation of endogenous peptide antigen via MHC class I | biological process | GO:0019885 | 38 | 10 | 20694 | 1406 |
H2-T10,H2-M2,H2-T24,H2-Q7,Tap2,H2-Q4,Tap1,Tapbp,H2-Q6,H2-T22 |
| 1.660e-04 | -8.70 | GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_DN | 186 | 30 | 15632 | 1249 |
Il4ra,Socs1,Gbe1,Upp1,Cdkn2d,Tnfaip3,Aff1,Herc3,N4bp1,Bcl2a1b,Klf6,Bcl2a1d,Mdn1,Irf4,Tcea1,Tax1bp1,Bcl2a1a,Gna15,Rnf14,Plek,Junb,Jarid2,Pdk3,Spint2,Rasgrp1,Slc39a14,Piezo1,Trip13,Zfp36,Slc7a5 |
| 1.668e-04 | -8.70 | Tnfaip3 (tumor necrosis factor, alpha-induced protein 3) | protein interactions | 21929 | 23 | 9 | 7778 | 753 |
Il1b,Tax1bp1,Traf2,Casp1,Tnfaip3,Tnip3,Tnf,Tnip1,Ikbkg |
| 1.677e-04 | -8.69 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | MSigDB lists | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | 39 | 11 | 15632 | 1249 |
Phf11b,Pik3r5,Syk,Phf11d,Cyth3,Itpr1,Lyn,Nr4a3,Akt3,Phf11a,Phf11c |
| 1.677e-04 | -8.69 | AMIT_EGF_RESPONSE_120_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_120_MCF10A | 39 | 11 | 15632 | 1249 |
Gdf15,Lif,Txnrd1,Dusp6,Il1a,Trim21,Phlda1,Serpinb2,Plaur,Maff,Il1b |
| 1.688e-04 | -8.69 | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN | 73 | 16 | 15632 | 1249 |
Myc,Pnp2,Ifrd1,Hdac1,Met,Gsr,Birc3,Nfkbia,Atm,Irf7,Plau,Tnfsf10,Il1b,Upp1,Ak4,Rtp4 |
| 1.692e-04 | -8.68 | WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 | MSigDB lists | WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 | 52 | 13 | 15632 | 1249 |
Inhba,Ccnd1,Itgb8,Edn1,Jun,Cav1,Axl,Fam43a,P4ha2,Plaur,Adam19,Plat,Itga4 |
| 1.693e-04 | -8.68 | regulation of myoblast fusion | biological process | GO:1901739 | 25 | 8 | 20694 | 1406 |
Cxcl10,Cxcl9,Gdf15,Ccl8,Tnfsf14,Cflar,Ehd1,Il4ra |
| 1.700e-04 | -8.68 | GSE3720_UNSTIM_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN | MSigDB lists | GSE3720_UNSTIM_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN | 169 | 28 | 15632 | 1249 |
Sdc4,Gbp2,Rgs3,Lrch3,Agtrap,Nr3c1,Phgdh,D1Ertd622e,Gsr,N4bp1,Pik3r5,Cenpe,Nlrc5,Dse,Acsl5,Osbpl3,Nfil3,Tmod3,Rnf19b,Lyn,Slc43a3,Csf1,Zc3h7a,Il18rap,Hk2,Sirt1,Plek,Cd86 |
| 1.700e-04 | -8.68 | GO_KINASE_REGULATOR_ACTIVITY | MSigDB lists | GO_KINASE_REGULATOR_ACTIVITY | 169 | 28 | 15632 | 1249 |
Flrt2,Pik3r6,Map2k1,Ccl5,Ccne1,Trib3,Trib1,Cxcl10,Socs3,Prkar2b,Socs7,Cdkn1a,Pik3r5,Flrt3,Ccnd1,Casp3,Spry2,Cish,Kat2b,Cdk5r1,Socs1,Nck1,Malt1,Cdkn2d,Rhoh,Spred1,Mark2,Daxx |
| 1.705e-04 | -8.68 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | 195 | 31 | 15632 | 1249 |
Mdm2,Bnip3,Rhbdf2,N4bp1,Tagln,P4ha2,Tap1,Apaf1,Gbe1,Upp1,Hk2,Egln3,Rnf19a,Phlda1,Btg2,Ddit4,Fabp7,Sap30,Plod2,Plekha2,Higd1a,Cav1,P4ha1,Jdp2,Pde4b,Nampt,Pgk1,Cdkn1a,Fam162a,Pfkl,Ier3 |
| 1.705e-04 | -8.68 | GSE33425_CD161_INT_VS_NEG_CD8_TCELL_DN | MSigDB lists | GSE33425_CD161_INT_VS_NEG_CD8_TCELL_DN | 195 | 31 | 15632 | 1249 |
Lyn,Map3k8,Fndc3a,Plaur,Zc3h12c,Snx10,Tor3a,Slc4a7,Myadm,Snx2,Tmem176a,Rab10,Plscr1,H2-Aa,Stxbp3,Cd74,Cd38,Mdfic,Hck,Ciita,Cd83,Cyfip1,Tcf4,Mgat1,Cd40,Tiparp,Plac8,Syk,Ctsc,Slc44a1,Rhoq |
| 1.706e-04 | -8.68 | GO_REGULATION_OF_CELL_CYCLE | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE | 857 | 98 | 15632 | 1249 |
Casp2,Ube2e2,Sirt1,Ccne1,Psmb8,Dach1,Eif4g2,Ptch1,Tmem67,Tmod3,Irf1,Myc,Pdpn,Prkce,Edn1,Bcl2l11,Cenpe,Jun,Psmd10,Pnpt1,Tnks1bp1,Chmp4b,Atp2b4,Prnp,Ccnd2,Phip,Plagl1,Pttg1,Btg2,Pdgfb,Junb,Plk2,Thbs1,Smc5,Prdm9,Il12b,Ptgs2,Pim1,Casp3,Psma6,Mdm2,Ccnd1,Src,Dusp1,Birc2,Psmb9,Bmp2,Crlf3,Lif,Pml,Hhex,Ube2e1,Psme1,Sphk1,Il1a,Psme2,Trim21,Atm,Cenpj,Pid1,Notch2,Cdkn1a,Pim2,Gadd45g,Phactr4,Cnot4,Nr4a1,Trim36,Gadd45b,Cited2,Pim3,Rbl1,Cdkn2d,Nek6,Tpx2,Cdk5r1,Kat2b,Gpr132,Inhba,Pdgfrb,Osm,Map2k1,Asns,Ppp1r15a,Il1b,Pkp4,Psmb6,Parp3,Nr4a3,Stat3,Ccng2,Hspa2,Ankrd17,Pbx1,Tnfaip3,Nupr1,Plk3,Psmb10 |
| 1.712e-04 | -8.67 | heterocycle catabolic process | biological process | GO:0046700 | 280 | 36 | 20694 | 1406 |
Helz2,Tent2,Xrn1,Gsta3,Zhx2,Hmox1,Dnase1l3,Oas2,Pde5a,Zfp36,Dcp1a,Zc3h12a,Gda,Polr2g,Tet2,Enpp4,Kmo,Atm,Tent4a,Upp1,Hdc,Apobec3,Magohb,Pnpt1,Mgat1,Dcp2,Gtpbp2,Slfn8,Tut7,Noct,Isg20,Cnp,Rnaset2a,Samhd1,Ago3,Smg7 |
| 1.720e-04 | -8.67 | ST_GA13_PATHWAY | MSigDB lists | ST_GA13_PATHWAY | 33 | 10 | 15632 | 1249 |
Nfkbie,Nfkbib,Nfkb2,Akt3,Map2k4,Nfkb1,Ikbkg,Nfkbia,Ptk2,Nfkbil1 |
| 1.720e-04 | -8.67 | ONGUSAHA_TP53_TARGETS | MSigDB lists | ONGUSAHA_TP53_TARGETS | 33 | 10 | 15632 | 1249 |
Fas,Col18a1,Mdm2,Cdkn1a,Tap1,Dgka,Nqo1,Srxn1,Sat1,Ddit4 |
| 1.720e-04 | -8.67 | KEGG_PRION_DISEASES | MSigDB lists | KEGG_PRION_DISEASES | 33 | 10 | 15632 | 1249 |
Ccl5,Egr1,Map2k1,Prnp,Il1a,Il6,Prkx,Il1b,Stip1,Notch1 |
| 1.720e-04 | -8.67 | GO_MONOCYTE_CHEMOTAXIS | MSigDB lists | GO_MONOCYTE_CHEMOTAXIS | 33 | 10 | 15632 | 1249 |
Cx3cl1,Ccl22,Ccl5,Ccl12,Flt1,Ccl3,Ccl2,Il6,Ccl4,Pdgfb |
| 1.730e-04 | -8.66 | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | MSigDB lists | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | 88 | 18 | 15632 | 1249 |
Asap3,Crkl,Marcksl1,Sphk1,Pik3cd,Lyn,Pikfyve,Fcgr1,Myo10,Hck,Pik3r5,Syk,Map2k1,Prkce,Akt3,Fcgr2b,Pla2g4a,Vasp |
| 1.730e-04 | -8.66 | KIM_MYCN_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYCN_AMPLIFICATION_TARGETS_DN | 88 | 18 | 15632 | 1249 |
Plekha2,Plekhg1,B4galt4,Apobec3,Plekha5,Fam43a,Ppp2r3a,Optn,Itgb8,Xrn1,Fam111a,Ttc39b,Pik3cd,Atp11b,Cd164,Lipg,Gca,Cflar |
| 1.735e-04 | -8.66 | REL_1 | prosite domains | PS01204 | 5 | 4 | 13278 | 1037 |
Nfkb1,Relb,Nfkb2,Rel |
| 1.746e-04 | -8.65 | PID_BCR_5PATHWAY | MSigDB lists | PID_BCR_5PATHWAY | 66 | 15 | 15632 | 1249 |
Lyn,Malt1,Bcl2a1a,Map2k1,Jun,Fos,Bcl2a1b,Ikbkg,Nfkb1,Syk,Nfkbia,Bcl2a1d,Pou2f2,Nfkbib,Fcgr2b |
| 1.753e-04 | -8.65 | REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS | MSigDB lists | REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS | 59 | 14 | 15632 | 1249 |
Nfkbib,Psme2,Psma6,Nfkbie,Ikbkg,Nfkbia,Psmb8,Rel,Psmd10,Psmb9,Psmb6,Malt1,Psme1,Psmb10 |
| 1.772e-04 | -8.64 | GSE360_L_DONOVANI_VS_T_GONDII_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_T_GONDII_MAC_UP | 178 | 29 | 15632 | 1249 |
Tmem184b,Aoah,4932438A13Rik,Tlk2,Vcan,Pdpn,Ccl2,Fchsd2,Nr1h3,St3gal6,Fabp3,Aldh1b1,Plk3,Sla,Serpine1,Tnfsf14,Ccr1,Hk2,Ampd3,Ptafr,Kcna3,Hmox1,Itpkc,Acp2,Il1b,Htr2b,Hcls1,Asf1a,Serpinb2 |
| 1.772e-04 | -8.64 | GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | MSigDB lists | GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | 178 | 29 | 15632 | 1249 |
Nck1,Cyth3,Calcrl,Il4ra,Slc30a1,Crlf3,Herc3,Nod1,Gpc1,Rab3ip,Enpp4,Myo10,Cnn2,Rgs14,Tiparp,Bbx,Pde5a,Traf3ip2,Ms4a6d,Adrb2,Cflar,Rsbn1,Ldlr,Card6,Ppm1k,Daam1,Osm,Casp8,Rasgrp1 |
| 1.772e-04 | -8.64 | GSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN | 178 | 29 | 15632 | 1249 |
Jun,Hspa1a,Ptpn2,Adhfe1,Hivep2,Trim36,Dusp1,Plod3,N4bp1,Cers6,Dusp4,Phgdh,Itgb8,Usp18,Ube2e1,Nck1,Sipa1l1,Layn,Lmo4,Cox18,Spire1,Ier3,Naa25,Zc3h12a,Ell2,Esd,Gtpbp2,Rgs1,Clic4 |
| 1.772e-04 | -8.64 | GSE34515_CD16_NEG_VS_POS_MONOCYTE_UP | MSigDB lists | GSE34515_CD16_NEG_VS_POS_MONOCYTE_UP | 178 | 29 | 15632 | 1249 |
Trib1,Ier3,Ripk2,Nfil3,Glrx,Jak2,Ldlr,Clic4,Fam20c,Cd274,Flrt2,Slc7a2,Ccne1,Rasgrp1,Rab10,Psmb10,Aldh1b1,Slc30a4,Traf5,F10,Slc16a1,Slc48a1,Zbp1,Cd40,Ppp1r14b,Dusp4,Irf4,Slc15a3,Fchsd2 |
| 1.772e-04 | -8.64 | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_UP | MSigDB lists | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_UP | 178 | 29 | 15632 | 1249 |
Cnn2,Slc25a37,Slc7a11,Spry2,Rhoq,Palld,Rnf139,Arl4a,Traf1,Bfar,Plau,Pfkfb3,Sdc4,Rgs3,Dusp14,Eno2,Rrs1,Ptch1,Spen,St3gal5,Phlpp2,Smox,Odc1,Pik3cd,Kif3c,Rap2c,Bambi,Slc29a3,Ppfibp2 |
| 1.777e-04 | -8.64 | plasma membrane receptor complex | cellular component | GO:0098802 | 178 | 26 | 20747 | 1409 |
Itgav,Calcrl,Il6,Rnf31,Itgal,Traf5,Tlr2,Itga5,Itgb8,Ebi3,Itga9,Syk,Il12rb1,Birc2,Il18rap,Tlr6,Acvr1b,Igf1r,Traf2,Itga4,Lyn,Acvrl1,Acvr1,Cd40,Tlr1,Bmp2 |
| 1.783e-04 | -8.63 | fibronectin binding | molecular function | GO:0001968 | 31 | 9 | 20217 | 1400 |
Itgav,Thbs1,Sdc4,Plekha2,Mmp9,Mmp13,Tnc,Itga4,Hsd17b12 |
| 1.789e-04 | -8.63 | regulation of response to wounding | biological process | GO:1903034 | 178 | 26 | 20694 | 1406 |
Prkce,Lyn,Cav1,Serpine1,Kremen1,Gja1,Igf1r,Scarf1,Enpp4,Hopx,Pdpn,Plpp3,Ptger4,Ubash3b,Pdgfb,Syk,Ptprj,Map2k1,Cdkn1a,Il10,Ccl2,Plau,Plek,Thbs1,Adrb2,Cd34 |
| 1.804e-04 | -8.62 | modification of morphology or physiology of other organism involved in symbiotic interaction | biological process | GO:0051817 | 94 | 17 | 20694 | 1406 |
Tlr2,Serpinb9,Ccl5,Irgm2,Tnip1,Jun,Pcx,Ccl4,Rab9,Mmp9,Bcl2l11,Trem1,Irgm1,Zc3h12a,Pf4,Myc,Hdac1 |
| 1.804e-04 | -8.62 | regulation of JUN kinase activity | biological process | GO:0043506 | 94 | 17 | 20694 | 1406 |
Map2k4,Il1rn,Il1b,Fzd5,Tlr9,Aida,Mlkl,Mdfic,Tnf,Mapkbp1,Mul1,Ripk2,Edn1,Tlr6,Traf2,Dnaja1,Syk |
| 1.813e-04 | -8.62 | regulation of vascular smooth muscle cell proliferation | biological process | GO:1904705 | 53 | 12 | 20694 | 1406 |
Il10,Cdkn1a,Mmp9,Mdm2,Nr4a3,Hmox1,Tnf,Jun,Sod2,Jak2,Edn1,Pdgfb |
| 1.813e-04 | -8.62 | MHC class I peptide loading complex | cellular component | GO:0042824 | 14 | 6 | 20747 | 1409 |
H2-Q4,Tapbp,Tap2,H2-Q7,H2-Q6,Tap1 |
| 1.817e-04 | -8.61 | response to growth hormone | biological process | GO:0060416 | 14 | 6 | 20694 | 1406 |
Stat3,Irf1,Jak2,Cacybp,Ptk2,Stat5a |
| 1.817e-04 | -8.61 | regulation of chemokine (C-X-C motif) ligand 2 production | biological process | GO:2000341 | 14 | 6 | 20694 | 1406 |
Mcoln2,Hdac1,Cd74,Ccl5,Tnf,Myd88 |
| 1.817e-04 | -8.61 | positive regulation of macrophage differentiation | biological process | GO:0045651 | 14 | 6 | 20694 | 1406 |
Csf1,Hcls1,Trib1,Casp8,Pf4,Lif |
| 1.817e-04 | -8.61 | negative regulation of tyrosine phosphorylation of STAT protein | biological process | GO:0042532 | 14 | 6 | 20694 | 1406 |
Socs3,Irf1,Ptpn2,Socs1,Parp14,Cav1 |
| 1.817e-04 | -8.61 | regulation of chemokine biosynthetic process | biological process | GO:0045073 | 14 | 6 | 20694 | 1406 |
Myd88,Egr1,Tnf,Il1b,Tlr3,Il6 |
| 1.822e-04 | -8.61 | GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB | MSigDB lists | GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB | 136 | 24 | 15632 | 1249 |
Rtp4,Gbp3,Ifi214,Ifi207,Ifi205,Ifi209,Ifi213,Lipe,Morc3,S1pr2,Sat1,Acsl1,Ifi204,Egr3,Sp110,Irf7,Mndal,Plod2,Snx10,H2-Eb1,Ifi203,Ifi208,Ifi211,Tmeff1 |
| 1.829e-04 | -8.61 | GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | 187 | 30 | 15632 | 1249 |
Ppp2r1b,Rgs1,Dusp16,Ttc39b,Mafg,Nr4a3,Odc1,Plscr1,Egln3,Hivep3,Tnfrsf1b,Gja1,Psat1,Pdk3,Asns,Irf8,Ppfibp1,Mdfic,Cd38,Prnp,Plagl1,Rhoq,Cish,Tor1aip2,Irf4,Casp3,Cpd,Dusp4,Ift57,N4bp1 |
| 1.829e-04 | -8.61 | GSE7764_NKCELL_VS_SPLENOCYTE_UP | MSigDB lists | GSE7764_NKCELL_VS_SPLENOCYTE_UP | 187 | 30 | 15632 | 1249 |
Sema4c,Atp10a,Ptger4,Pim1,Sema4a,Cmklr1,Vegfc,Pkp4,Tnfsf14,Fzd5,Plod2,Gem,Plscr1,Mmd,Il18rap,Rap1gap2,Ubash3b,Rab19,Mpp7,Mul1,P2ry14,Znrf3,Agtrap,Nod1,Rhoc,Klf6,Plekha5,Ttc39c,Abcb1a,Spry2 |
| 1.829e-04 | -8.61 | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP | MSigDB lists | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP | 187 | 30 | 15632 | 1249 |
Socs1,Sell,Il4ra,Ccnd2,Rhoh,Evl,Daxx,Ets2,Bcl6,Ppp1r14b,Abcc5,Peli1,Slc44a1,Mdn1,Nr4a3,Wdr43,Frmd6,Ikbke,Irf7,Klf2,Ubr4,Dgka,Uba7,Stx6,Psme2,Ampd3,Inpp5b,Ext1,Ddit4,Cnn3 |
| 1.829e-04 | -8.61 | GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_DN | 187 | 30 | 15632 | 1249 |
Mtmr14,Cd200,Tmem229b,Rcn1,Gpd2,Irak2,Cd82,Lhx2,Vrk2,Mthfd1l,Arid4a,Golga3,Map2k1,Gpr132,Etv6,Atf3,Egr1,Zfp281,Ifih1,Trim12c,Trp53i11,Rnd3,Apaf1,Atp11b,Plagl2,Birc2,Peli1,Cept1,Mlkl,Dock10 |
| 1.839e-04 | -8.60 | Interferon_reg_fac_CS | interpro domains | IPR019817 | 9 | 5 | 19984 | 1430 |
Irf2,Irf8,Irf1,Irf7,Irf4 |
| 1.839e-04 | -8.60 | Interferon_reg_fact_DNA-bd_dom | interpro domains | IPR001346 | 9 | 5 | 19984 | 1430 |
Irf8,Irf2,Irf7,Irf4,Irf1 |
| 1.864e-04 | -8.59 | Class I MHC mediated antigen processing & presentation | REACTOME pathways | R-MMU-983169 | 212 | 35 | 8608 | 757 |
Psmb10,H2-Q6,Znrf1,Herc6,Psmb8,H2-T24,Rnf19b,Tap1,H2-M2,Psmd10,H2-Q4,Psme2,Psma6,Sec24b,H2-Q7,Psmb9,Fcgr1,Psme1,H2-T10,Rnf114,Psmb6,Spsb1,Lnpep,Tapbp,Fbxo4,Psme2b,Uba7,Tap2,Sec24a,Rnf19a,Dtx3l,Trim36,H2-T22,Trim21,Itgav |
| 1.870e-04 | -8.58 | cell-substrate adherens junction | cellular component | GO:0005924 | 159 | 24 | 20747 | 1409 |
Pdlim7,Itga5,Keap1,Dst,Ptk2,Itgb8,Asap3,Ezr,Flnb,Zyx,Map2k1,Itgav,Vasp,Evl,Irf2,Jak2,Flrt3,Hck,Flrt2,Prag1,Syne2,Map4k4,Cav1,Sdc4 |
| 1.872e-04 | -8.58 | transcription corepressor activity | molecular function | GO:0003714 | 185 | 27 | 20217 | 1400 |
Dr1,Hspa1a,Tcf4,Sap30,Riox2,Rbbp8,Hdac1,Kmt5a,Cdyl,Arid5a,Ccnd1,Parp9,Zfp281,Cited2,Zhx2,Jdp2,Cdyl2,Aebp2,Spen,Sirt1,Trib3,Tle3,Mier3,Kdm5b,Bcor,Daxx,Cenpj |
| 1.873e-04 | -8.58 | GO_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING | 81 | 17 | 15632 | 1249 |
Pik3r5,Src,Axl,Tnf,Txn1,Csf3,Rictor,Il6,Spry2,Ptprj,Mtdh,Ptk2,Angpt1,Gcnt2,Hcls1,Thbs1,F10 |
| 1.873e-04 | -8.58 | PID_REG_GR_PATHWAY | MSigDB lists | PID_REG_GR_PATHWAY | 81 | 17 | 15632 | 1249 |
Nfkb1,Nr4a1,Stat5a,Jun,Fos,Il6,Nr3c1,Sele,Hdac1,Mdm2,Stat1,Egr1,Cdk5r1,Icam1,Irf1,Pbx1,Cdkn1a |
| 1.879e-04 | -8.58 | GO_REGULATION_OF_NECROTIC_CELL_DEATH | MSigDB lists | GO_REGULATION_OF_NECROTIC_CELL_DEATH | 22 | 8 | 15632 | 1249 |
Tspo,Cflar,Ripk3,Birc3,Birc2,Casp8,Cav1,Traf2 |
| 1.879e-04 | -8.58 | WILLERT_WNT_SIGNALING | MSigDB lists | WILLERT_WNT_SIGNALING | 22 | 8 | 15632 | 1249 |
Gypc,Ednrb,Gja1,Slc2a1,Cited2,Nsmaf,Vcan,Ccnd1 |
| 1.879e-04 | -8.58 | BIOCARTA_NTHI_PATHWAY | MSigDB lists | BIOCARTA_NTHI_PATHWAY | 22 | 8 | 15632 | 1249 |
Tnf,Dusp1,Nfkbia,Nfkb1,Tlr2,Nr3c1,Myd88,Il1b |
| 1.879e-04 | -8.58 | BIOCARTA_NFKB_PATHWAY | MSigDB lists | BIOCARTA_NFKB_PATHWAY | 22 | 8 | 15632 | 1249 |
Myd88,Tnfaip3,Nfkbia,Tnf,Nfkb1,Tnfrsf1b,Ikbkg,Il1a |
| 1.879e-04 | -8.58 | GO_CELLULAR_EXTRAVASATION | MSigDB lists | GO_CELLULAR_EXTRAVASATION | 22 | 8 | 15632 | 1249 |
Sele,Trem1,Vcam1,Pik3cd,Cx3cl1,Ccl12,Tnf,Itga4 |
| 1.879e-04 | -8.58 | GO_REGULATION_OF_RESPONSE_TO_INTERFERON_GAMMA | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_INTERFERON_GAMMA | 22 | 8 | 15632 | 1249 |
Parp9,Jak2,Nr1h3,Socs1,Ptpn2,Stat1,Socs3,Nlrc5 |
| 1.879e-04 | -8.58 | GO_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE | MSigDB lists | GO_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE | 22 | 8 | 15632 | 1249 |
Il12b,Il4ra,Il12rb1,Ripk2,Cd80,Il27,Tnfsf4,Hlx |
| 1.884e-04 | -8.58 | GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_UP | MSigDB lists | GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_UP | 170 | 28 | 15632 | 1249 |
Sphk1,Mcm10,Plk3,Nfkbiz,Lrp8,Etv5,Rras2,Pfkfb3,Dnaja1,Slc2a1,Klf6,Ggct,Dusp2,Pnp2,Ptgs2,Trib1,Serpinb9,Nr4a3,Cd55,Tnfsf10,Samsn1,Klf2,Mthfd1l,Mmd,Stat4,Stx11,Zeb1,Pdss1 |
| 1.884e-04 | -8.58 | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 170 | 28 | 15632 | 1249 |
Hlx,Rhoh,Trim13,1600014C10Rik,Gadd45b,Mrpl52,Dse,Gpr84,Rab21,Tbc1d1,Cox17,Stk40,Ptgir,Nr4a3,Lyn,Acsl5,Jak2,Ust,4930523C07Rik,Mthfd1l,Zc3h12c,Plekhg1,Sipa1l1,Serpine1,Csf1,Trim26,Hivep3,Ccrl2 |
| 1.884e-04 | -8.58 | GSE2585_THYMIC_DC_VS_MTEC_DN | MSigDB lists | GSE2585_THYMIC_DC_VS_MTEC_DN | 170 | 28 | 15632 | 1249 |
Isg15,Rhoh,Irak3,Clec4e,Tcf4,Plac8,Rsad2,Psma6,4932438A13Rik,Rnf24,Ccl2,Ifit3b,Cxcl10,Larp1,Rnf19b,Ppfibp2,Clic4,Tnfsf10,Thbs1,Lap3,Slc7a2,Rel,Ifit3,Oas2,Stoml1,Plscr1,Isg20,Bcl9 |
| 1.884e-04 | -8.58 | GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_UP | 170 | 28 | 15632 | 1249 |
Ak4,Ptgs2,Dusp5,Ripk2,Rnf19b,Ppp2r2a,Il1b,Igf1r,Ccl4,Ust,Serpinb2,Ascc3,Stx11,Adora2a,Tdrd7,Zfp36,Timeless,Irs2,Traf1,Ier2,Mxd1,Plk3,Atp11b,Cdc42ep2,Gpsm2,Cpd,Il6,Mmp14 |
| 1.884e-04 | -8.58 | GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_DN | MSigDB lists | GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_DN | 170 | 28 | 15632 | 1249 |
Pgk1,Rcan1,Il12b,Pstpip2,Ksr1,Rapgef2,Usp12,Rabgef1,Pde4b,Lnpep,Csrp1,Sdc4,Aff1,Mcmbp,Tle3,Atf3,Fas,Socs1,Nxf1,Ggct,Minpp1,Dusp2,Peli1,Nfkbie,Taf4b,Scarf1,Psma6,Slc25a37 |
| 1.884e-04 | -8.58 | negative regulation of catabolic process | biological process | GO:0009895 | 292 | 37 | 20694 | 1406 |
Kdm4a,Atp2b4,Pde3b,Tent4a,Ric1,Usp25,Tspo,Nos2,Tnf,N4bp1,Noct,Stat3,Myd88,Il10,Pml,Nampt,Sco1,Ddit4,Eif4g2,Tlk2,Caml,Larp1,Tent2,Timp1,Htr2b,Tnfaip3,Hmox1,Hcar2,Nupr1,Irak3,Zfp36,Ier3,Ptk2,Mapkapk2,Hp,Chmp4b,Il1b |
| 1.887e-04 | -8.58 | GO_HUMORAL_IMMUNE_RESPONSE | MSigDB lists | GO_HUMORAL_IMMUNE_RESPONSE | 153 | 26 | 15632 | 1249 |
Slpi,Ifna6,Bst1,Pou2f2,H2-Eb1,C1rl,Trem1,Ebi3,Cd55,H2-Ab1,C3,Traf3ip2,Il6,C1ra,Ifna5,Ifnb1,Tnf,H2-Q4,Ccl12,H2-Q6,Ifna1,Cd83,Notch1,Ifna2,H2-Q7,Psmb10 |
| 1.894e-04 | -8.57 | positive regulation of mitotic nuclear division | biological process | GO:0045840 | 61 | 13 | 20694 | 1406 |
Pdgfrb,Met,Il1b,Edn1,Phip,Cenpe,Sphk1,Pdgfb,Igf1r,Tnf,Smc5,Il1a,Rgcc |
| 1.899e-04 | -8.57 | IRF | pfam domains | PF00605 | 9 | 5 | 18711 | 1348 |
Irf7,Irf4,Irf1,Irf8,Irf2 |
| 1.904e-04 | -8.57 | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | MSigDB lists | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | 1290 | 138 | 15632 | 1249 |
Tpi1,Nck1,Fas,Ahr,Slc16a1,Pilrb2,Cited2,Ets2,Sod2,Sqstm1,Dhrs9,Psip1,Crbn,Cpd,Ifrd1,Ap3b1,Stap1,Katna1,Gclm,Bnip3,Lyn,Mthfd2,Odc1,Hmgcs1,Abcc1,Vrk2,Ppp2r1b,Tax1bp1,Rap2c,Cd82,Fscn1,Arf4,Rbms1,Lmo4,Plod2,Casp8,Hdc,Nfkb1,Rnf14,Hk1,Med13,Alas1,Csf1,Pstpip2,F11r,Zfp281,Pdgfc,Stau1,Sla,Sav1,Arhgef3,Txnrd1,Stat5a,Hdac1,Cycs,Stat3,Adora2b,Phyh,Crkl,Pgk1,Il1b,Keap1,Rcl1,Pkp4,Inpp1,Cldnd1,Pilrb1,Map2k1,Med21,Cacybp,Lcp2,Cdyl,Hsd17b12,Spint2,Rapgef2,Stxbp3,Gbe1,Trim13,Gclc,Rras2,Psmd10,Tra2a,Ppp2r5a,Myc,Ikzf1,Acsl1,Tmod3,Etnk1,Kpna3,Prkar2b,Dr1,Cflar,P4ha1,Eif4g2,Hat1,Stat4,Sirt1,Plscr1,Ampd3,Rhoh,Itga4,Marcksl1,Ube2e1,Birc2,Slc2a1,Rbbp8,Timp1,Hsph1,Ehd1,Gsr,Kdm5b,Acvr1,Pnp2,Cish,Rab9,Minpp1,Casp3,Nsmaf,Chic2,Pim1,Dnaja2,Cd55,Larp1,Tcea1,Sec24b,Abcc4,Clic4,Acsl5,Dek,Samsn1,Map4k4,Nampt,Txn1,Hk2,G3bp2,Nmi,Slc7a5,Caml |
| 1.913e-04 | -8.56 | non-membrane spanning protein tyrosine kinase activity | molecular function | GO:0004715 | 45 | 11 | 20217 | 1400 |
Ripk2,Syk,Ptk2,Eif2ak2,Hck,Src,Sla,Fgr,Tyk2,Lyn,Jak2 |
| 1.916e-04 | -8.56 | vesicle-mediated transport | biological process | GO:0016192 | 1069 | 103 | 20694 | 1406 |
Dennd1b,Lrp8,Rubcnl,Carmil1,Stx6,Rhoq,Hspa2,Rac3,Nr1h3,Itga4,Dtx3l,Vps54,Rhou,Ap3b1,Rab11fip1,Fchsd2,Ehd1,Xkr8,Scyl2,Ezr,Ppfia3,Fcgr1,Adrb2,Lrp11,Marco,Rin2,Rab19,Cd302,Scarf1,Trip10,Itgal,Optn,Arl4a,Lrp4,Cyth3,Ptafr,Ldlr,Sec24a,Ly75,4932438A13Rik,Stx11,Hap1,Fpr2,Micall2,Snx10,Src,Myo1b,Hck,Treml4,Rabgef1,Chic2,Rab10,Ccl5,Calcrl,Jmjd6,Stxbp3,Msr1,Dennd2a,Arl5b,Nlgn2,Tnfaip2,Actb,Cd14,Sec24b,Snx2,Fcho2,Stxbp1,Ric1,Sh3bp4,Syk,Rasgrp1,Fcgr2b,Pikfyve,Ccr1,Rab20,Met,Myd88,Fnbp1l,Milr1,Arl5c,Spire1,Clcn5,Nr4a3,Cav1,Lyn,Rims3,Samd9l,Itgav,Htr2b,Dbnl,Rab32,Mapkapk2,Axl,Mppe1,Irf8,Arf4,Reps1,Ap3m2,Whamm,Rab9,Plek,Thbs1,Grk3 |
| 1.932e-04 | -8.55 | purinergic receptor activity | molecular function | GO:0035586 | 25 | 8 | 20217 | 1400 |
P2ry14,P2ry13,P2ry12,Adora2a,P2ry2,Hcar2,Adora2b,Ptafr |
| 1.938e-04 | -8.55 | ZHENG_GLIOBLASTOMA_PLASTICITY_UP | MSigDB lists | ZHENG_GLIOBLASTOMA_PLASTICITY_UP | 232 | 35 | 15632 | 1249 |
Rbl1,Angpt1,Cd38,Etv5,Rnd3,Sdc4,Tpx2,Ccnd2,Upp1,Nupr1,Dusp4,Ccnd1,Psd,Cp,Pdpn,Cd302,Ass1,Idi1,Mthfd2,Mcm6,Gpd2,Ier3,Lyn,Il13ra1,Tdrd7,Pla2g7,Jag1,Sh3bp4,Scn1b,Tmeff1,Myo1b,Hopx,Ednrb,Dusp6,Tuba4a |
| 1.939e-04 | -8.55 | ZHOU_TNF_SIGNALING_30MIN | MSigDB lists | ZHOU_TNF_SIGNALING_30MIN | 46 | 12 | 15632 | 1249 |
Tuba4a,Junb,Dusp1,Nfkbia,Hmga1,Map2k1,Il6,Prdx5,Egr1,Ier2,Ptgs2,Tnfaip3 |
| 1.939e-04 | -8.55 | HUPER_BREAST_BASAL_VS_LUMINAL_UP | MSigDB lists | HUPER_BREAST_BASAL_VS_LUMINAL_UP | 46 | 12 | 15632 | 1249 |
Slpi,Htra1,Pdpn,Jag1,Ptges,Il1b,Cxcl14,S100a8,Flrt3,Gja1,Sdc1,Il1a |
| 1.944e-04 | -8.55 | GO_CYTOKINE_METABOLIC_PROCESS | MSigDB lists | GO_CYTOKINE_METABOLIC_PROCESS | 17 | 7 | 15632 | 1249 |
Il12b,Irf7,Il18,Ifnar1,Trem1,Nod1,Tnfsf15 |
| 1.944e-04 | -8.55 | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | MSigDB lists | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | 17 | 7 | 15632 | 1249 |
Nfkbia,Tlr3,Ikbkg,Ripk3,Zbp1,Nfkbib,Nfkb2 |
| 1.944e-04 | -8.55 | LEI_HOXC8_TARGETS_DN | MSigDB lists | LEI_HOXC8_TARGETS_DN | 17 | 7 | 15632 | 1249 |
Nqo1,Adam19,Plagl1,Cxcl10,Fam43a,Tagln,Ass1 |
| 1.944e-04 | -8.55 | GO_K63_LINKED_POLYUBIQUITIN_BINDING | MSigDB lists | GO_K63_LINKED_POLYUBIQUITIN_BINDING | 17 | 7 | 15632 | 1249 |
Parp10,Ikbkg,Sqstm1,Tab2,Ikbke,Optn,Tnfaip3 |
| 1.944e-04 | -8.55 | SA_CASPASE_CASCADE | MSigDB lists | SA_CASPASE_CASCADE | 17 | 7 | 15632 | 1249 |
Casp3,Apaf1,Fas,Birc3,Casp7,Casp8,Birc2 |
| 1.944e-04 | -8.55 | ZHANG_RESPONSE_TO_CANTHARIDIN_UP | MSigDB lists | ZHANG_RESPONSE_TO_CANTHARIDIN_UP | 17 | 7 | 15632 | 1249 |
Nampt,Fpr1,Trim13,Il1a,Btg2,Nfil3,Ifrd1 |
| 1.944e-04 | -8.55 | GO_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | 17 | 7 | 15632 | 1249 |
Tnfaip3,Trib1,Cd180,Trim12c,Nfkbil1,Prdm1,Cd55 |
| 1.944e-04 | -8.55 | VERNELL_RETINOBLASTOMA_PATHWAY_DN | MSigDB lists | VERNELL_RETINOBLASTOMA_PATHWAY_DN | 17 | 7 | 15632 | 1249 |
Cited2,Serpine1,Itgb8,Ppfibp1,Pmepa1,Ccnd1,Sh3bp4 |
| 1.944e-04 | -8.55 | GO_REGULATION_OF_MONOCYTE_CHEMOTAXIS | MSigDB lists | GO_REGULATION_OF_MONOCYTE_CHEMOTAXIS | 17 | 7 | 15632 | 1249 |
Ccl12,Ccl5,Ccr1,Cxcl10,Lyn,Serpine1,Pla2g7 |
| 1.944e-04 | -8.55 | TNF | smart domains | SM00207 | 16 | 7 | 9567 | 823 |
Tnfsf8,Tnfsf4,Tnf,Tnfsf10,Tnfsf14,Tnfsf9,Tnfsf15 |
| 1.955e-04 | -8.54 | GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D | MSigDB lists | GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D | 540 | 67 | 15632 | 1249 |
Fndc3a,Phf6,Fcho2,Frmd4a,Nr4a3,Map3k8,Rsbn1,Bambi,Dcbld2,Ppp2r2a,Zhx2,Slc4a7,Arid4a,Ccnj,Rgl1,Nrp2,Rab10,Phlpp2,Hif1a,Crim1,Plagl2,Rhoc,Ddhd1,Arhgef3,Serp1,Stat3,Dusp8,Rab11fip1,Egr2,Itgb8,Ccnd1,Mecp2,Zfp800,Ccng2,Cers6,Kpna3,Irf1,Asf1a,Ldlr,Chd9,Rap2c,Cdkn1a,Frmd6,Eif4g2,Mfap3l,Dcun1d3,Akt3,Rtn2,Cd69,Egln3,Stx6,Nkiras1,Ccnd2,Kat2b,Xrn1,Rbl1,Tnks1bp1,Flt1,Trim36,Gramd1a,Sqstm1,Bcl2l11,Znfx1,Trip10,Dusp2,Cnot4,Psd |
| 1.956e-04 | -8.54 | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | 179 | 29 | 15632 | 1249 |
Csf3,Met,S100a8,Eno2,Gja1,Znrf1,Cldnd1,Pmepa1,Rnf19b,Fndc3a,Slc43a3,Ttc39b,Ctsc,Cish,Aebp2,Pcx,Acvrl1,Plod3,Timp1,Tiparp,Zyx,Tspo,Hvcn1,Nek6,Hif1a,Prnp,Agtrap,Slco3a1,Irs2 |
| 1.956e-04 | -8.54 | GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | 179 | 29 | 15632 | 1249 |
Zhx2,Gca,Chic2,Dusp5,Itga5,Egr3,Max,Gpr132,Ddit4,Akt3,Fzd5,Junb,Samhd1,Tle3,Ncoa7,Trp53i11,Irs2,Egr1,Evl,Stk40,Glipr2,Egr2,Cited2,Gpr18,Fos,Ppp1r14b,Ass1,Apobec3,Lipe |
| 1.956e-04 | -8.54 | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN | 179 | 29 | 15632 | 1249 |
Cacybp,Irf8,Vps54,Jag1,Stx6,Pdss1,Irf1,Trib1,Cdc42ep4,Fam53c,Crkl,Dram1,Socs3,Rcl1,Stip1,Pkp4,Snn,Vrk2,Pcdh7,Tnfaip2,Ankrd17,Bcl6,Tank,Abcc5,Gclm,Ahr,Vcpip1,Mdfic,Il15 |
| 1.956e-04 | -8.54 | GSE3982_EOSINOPHIL_VS_BCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_BCELL_UP | 179 | 29 | 15632 | 1249 |
Jarid2,Tnfrsf1b,Ppp1r15a,Pstpip2,Ampd3,G3bp2,Jag1,Egln3,Adora2b,Trib1,Ptafr,Gpd2,Fpr1,Mmp25,Notch2,Gcnt2,Dcbld2,Ptges,Dusp1,Aoah,Klhl25,Cd302,Gpr35,Dennd1b,F11r,Sla,Hk3,Notch1,Hck |
| 1.956e-04 | -8.54 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_UP | 179 | 29 | 15632 | 1249 |
Klf6,Ifit1bl1,Rab32,Parp8,Apobec3,Zmynd15,Cd302,Ppp2r5a,Ogfrl1,Cnot4,Dhx58,Ddx60,Cdkn2d,Rnf135,Pikfyve,Crlf3,Rbm43,Olfml3,Ifit1bl2,Slc7a8,Cnp,Mmd,Uba7,Vasp,Mtmr14,Smox,Map3k8,Adrb2,Cxcl10 |
| 1.967e-04 | -8.53 | protein autophosphorylation | biological process | GO:0046777 | 199 | 28 | 20694 | 1406 |
Sla,Pim3,Prkx,Ptk2,Mark2,Mapkapk2,Pdgfrb,Irak2,Irak3,Ripk3,Hk1,Pim1,Lyn,Jak2,Igf1r,Fgr,Vrk2,Pim2,Hck,Met,Src,Eif2ak2,Acvr1b,Kdr,Flt1,Syk,Nek6,Atm |
| 1.995e-04 | -8.52 | GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_UP | MSigDB lists | GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_UP | 162 | 27 | 15632 | 1249 |
Pilrb2,Smg7,Irak3,Relb,Evl,Ier2,Usp18,Il4ra,Isg15,Rsad2,Ifit1bl1,Plac8,Oas3,Pilrb1,Rnf19b,Cd55,Ptprj,Larp1,Ifit3b,Ube2l6,Isg20,Plscr1,Stoml1,Oas2,Tyk2,Ifit1bl2,Ifit3 |
| 1.998e-04 | -8.52 | regulation of peptidyl-threonine phosphorylation | biological process | GO:0010799 | 46 | 11 | 20694 | 1406 |
Phip,Met,Sphk1,Tnks1bp1,S1pr2,Spred1,Ddit4,Spred3,Ripk2,Spry2,Irgm2 |
| 1.998e-04 | -8.52 | negative regulation of lymphocyte mediated immunity | biological process | GO:0002707 | 46 | 11 | 20694 | 1406 |
Spn,Bcl6,Tap1,Fcgr2b,Tap2,Clec2d,Serpinb9,Nod2,Ifnb1,Lgals9,Parp3 |
| 2.009e-04 | -8.51 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G | 89 | 18 | 15632 | 1249 |
Ccnd1,Itgav,Ppp6r1,Psd4,Cst7,Plk2,Sema3c,Swap70,Prkx,Hcls1,Gng12,Ppa1,Rhoh,Max,Dram1,Asb13,Il2rg,Tulp3 |
| 2.011e-04 | -8.51 | protein modification by small protein conjugation or removal | biological process | GO:0070647 | 621 | 66 | 20694 | 1406 |
Rnf14,Ankib1,Ube2e1,Mul1,Otud1,Traf2,Usp12,Usp25,Trim12c,Ubr4,Peli1,Sde2,Fbxo4,Trim30a,Usp53,Keap1,Tnfaip3,Usp35,Crbn,Bcor,Usp18,Znrf1,Vcpip1,Ranbp2,Dtx2,Isg15,Trim13,Zc3h12a,Spsb1,Rnf139,Sirt1,Mdm2,Arel1,Rffl,Pcgf5,Trim36,Trim12a,Rnf34,Egr2,Znrf3,Usp42,Rnf135,Usp31,Herc6,Dcun1d3,Uba7,Birc3,Trim56,Klhl25,Med21,Bfar,Arrdc4,Rnf19a,Ube2f,Uchl1,Trim21,Birc2,Ube2e2,Socs7,Ifih1,Cnot4,Rnf19b,Cop1,Malt1,Rnf31,Dtx3l |
| 2.014e-04 | -8.51 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_DN | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_DN | 188 | 30 | 15632 | 1249 |
Ifi213,Map3k6,Ifi205,Ifi209,Bcl6,Ikzf1,Ccnd1,Hspa2,Cxcl14,Rsad2,Ier2,Hlx,Sdc1,Ifi214,Slco3a1,F10,Mark2,Ifi207,Hk1,Mndal,Ifi211,Tmeff1,Ifi208,Inhba,Ifi203,Dennd2a,Ifi204,Tnip3,Snapc1,Hsd17b7 |
| 2.014e-04 | -8.51 | GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_UP | 188 | 30 | 15632 | 1249 |
Mmp13,Pstpip2,Btg2,Slpi,St3gal5,Ifit3,Sema3c,Klf2,Bcl2a1a,Tnip1,Tmem229b,Il12b,Ifit3b,Adrb2,Nr4a3,Ebi3,Rin2,Bcl2a1d,Irf4,Egr2,Znfx1,Hspa1a,Phldb1,Sqstm1,Bcl2a1b,Agrn,Traf5,Usp18,Traf1,Papss2 |
| 2.014e-04 | -8.51 | GSE5960_TH1_VS_ANERGIC_TH1_DN | MSigDB lists | GSE5960_TH1_VS_ANERGIC_TH1_DN | 188 | 30 | 15632 | 1249 |
Slc48a1,Tnfrsf8,Rbl1,Nek6,F11r,Slc44a1,Rhoq,Mecp2,Ap3b1,Mdm2,Cst7,Itgav,Ass1,Cyfip1,Polr2g,Nfkb2,Rnaset2b,Abcc1,Dtx2,Nr4a3,Ier3,Reps1,Rnf19a,Pdk3,Ccl5,Ccne1,Rnaset2a,Hopx,Fubp1,Map2k1 |
| 2.014e-04 | -8.51 | GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN | 188 | 30 | 15632 | 1249 |
Slc39a14,Phlda1,Slc7a5,Trip13,Osm,Dusp6,Stip1,Snapc1,Ier3,Mcm6,Ptgs2,Psmb6,Filip1l,Cd200,Etnk1,Cox17,Stap1,Rab11fip1,Irf4,Pla2g4a,Ggct,Eno1,Tspan3,Slc16a3,Cd38,Slc16a1,Sdc4,Lif,Egr1,Tpi1 |
| 2.019e-04 | -8.51 | positive regulation of osteoclast differentiation | biological process | GO:0045672 | 32 | 9 | 20694 | 1406 |
Gpr68,Notch2,Fos,Ccr1,Il12b,Ccl5,Csf1,Tnf,Ccl3 |
| 2.019e-04 | -8.51 | regulation of fatty acid transport | biological process | GO:2000191 | 32 | 9 | 20694 | 1406 |
Thbs1,Syk,Edn1,Fabp3,Irs2,Acsl5,Il1b,P2ry2,Il1a |
| 2.037e-04 | -8.50 | GO_CELL_SUBSTRATE_JUNCTION | MSigDB lists | GO_CELL_SUBSTRATE_JUNCTION | 373 | 50 | 15632 | 1249 |
Fzd1,Vasp,Rab10,Pdlim7,Flrt2,Map2k1,Pdgfrb,Gja1,Csrp1,Plaur,Keap1,Arhgap26,Rab21,Tnc,Hspa1a,Hck,Icam1,Itga4,Irf2,Asap3,Rhou,Syne2,Cnn3,Slc9a1,Procr,Flnb,Cav1,Lap3,Layn,Actb,Ptk2,Itga5,Triobp,Mmp14,Cyfip1,Zyx,Hmga1,Ezr,Cnn2,Flt1,Itgav,Flrt3,Ppfibp1,Rras2,Sdc4,Rnd3,Plau,Sdc1,Evl,Palld |
| 2.050e-04 | -8.49 | caveola | cellular component | GO:0005901 | 95 | 17 | 20747 | 1409 |
Sele,Lrp8,Ptgs2,Lipe,Ptch1,Igf1r,Adrb2,Cav1,Jak2,Asah2,Slc2a1,Src,P2ry12,Hmox1,Hk1,Hck,Ldlr |
| 2.060e-04 | -8.49 | regulation of calcium ion transport | biological process | GO:0051924 | 272 | 35 | 20694 | 1406 |
Pde4b,Pdgfrb,Serpine1,Lyn,Cav1,Ccl5,Ahr,Icam1,Prkce,Hspa2,Gja1,Itpr1,Homer1,Hap1,Pml,Ccr1,Ccl12,Gem,Slc9a1,Adrb2,Slc30a1,Tlr9,Cacnb3,Gpr35,Prnp,Cacna1d,Tspo,P2ry12,Ptgs2,Cx3cl1,Adora2a,Pdgfb,Ubash3b,Ccl4,Cxcl10 |
| 2.083e-04 | -8.48 | embryonic morphogenesis | biological process | GO:0048598 | 610 | 65 | 20694 | 1406 |
Plpp3,Tulp3,Vegfc,Phactr4,Cited2,Ets2,Lnpk,Socs3,Fzd1,Zfp281,Hdac1,Ift57,Apaf1,Casp8,Il10,Acvr1,Eya4,Intu,Sdc4,Edn1,Tshz1,Triobp,Ext1,Vcam1,Sema4c,Spry2,Notch2,Itga4,Sec24b,Myc,Rpgrip1l,Fzd5,Mmp14,Zeb1,Kdm6b,Clic5,Flt1,Mthfr,Itga5,Hif1a,Hlx,Lrp4,Vasp,Abr,Ttc39c,Lhx2,Bcl2l11,Casp3,Flrt3,Itgav,Htr2b,Ptch1,Lmo4,Gja1,Spint2,Foxp4,Inhba,Chst11,Pbx1,Nr4a3,Mthfd1l,Txnrd1,Gfi1,Hhex,Notch1 |
| 2.085e-04 | -8.48 | GSE24972_WT_VS_IRF8_KO_MARGINAL_ZONE_SPLEEN_BCELL_UP | MSigDB lists | GSE24972_WT_VS_IRF8_KO_MARGINAL_ZONE_SPLEEN_BCELL_UP | 171 | 28 | 15632 | 1249 |
Usp25,Col18a1,Csrnp1,Clcn5,Cd164,Gda,Mdfic,Myd88,Lipg,Jun,Cnn2,Map3k6,Dusp1,Ddhd1,Cept1,Dock10,Carhsp1,Pdzd11,Rcsd1,Mtdh,Mtmr14,Il1rn,Rgs1,Ikbkg,Parp12,Ext1,Htra1,Stxbp3 |
| 2.085e-04 | -8.48 | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 171 | 28 | 15632 | 1249 |
Rnaset2a,Itgal,C1rl,Fcgr4,Atm,4930523C07Rik,Slc12a9,Rap1gap2,Casp2,Inpp5b,Fcho2,Mppe1,Mmp25,Rnaset2b,Jak2,Adam19,Gca,Cx3cr1,Cebpd,Atp13a1,Tbc1d1,Carhsp1,Rnf135,Hk3,Apaf1,Mvp,Lpcat2,Tspo |
| 2.085e-04 | -8.48 | GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_DN | MSigDB lists | GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_DN | 171 | 28 | 15632 | 1249 |
Stat4,Hivep3,Dgka,Oas2,Isg20,Plscr1,Ifit3,Rnaset2a,Ifit1bl2,Rnf31,Rnaset2b,Tcea1,Pilrb1,Ifit3b,Ddx4,Tra2a,Rsad2,Katna1,Itgb8,Oas3,Ifit1bl1,Pilrb2,Nod1,Usp18,Isg15,Il4ra,Ier2,Rhoh |
| 2.086e-04 | -8.48 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | 67 | 15 | 15632 | 1249 |
Me1,Sdc4,Ifih1,Ifit3b,Prnp,Nupr1,C3,Cd55,Ppp2r5a,Ddit4,Abcb1a,Arhgef3,Ifit3,Lipe,Ifit2 |
| 2.092e-04 | -8.47 | regulation of glial cell proliferation | biological process | GO:0060251 | 39 | 10 | 20694 | 1406 |
Myc,Il6,Tnf,Il1b,Etv5,Notch1,Fas,Lyn,Tspo,Ptk2 |
| 2.099e-04 | -8.47 | BENPORATH_ES_CORE_NINE_CORRELATED | MSigDB lists | BENPORATH_ES_CORE_NINE_CORRELATED | 97 | 19 | 15632 | 1249 |
Hmga1,Lmo4,Nfkbie,Etv6,Sap30,Trip13,Nmi,Myc,Hif1a,Irf1,Mafg,Stat1,Rbl1,Plagl2,Nfil3,Relb,Dek,Zbtb5,Dr1 |
| 2.099e-04 | -8.47 | GO_POSITIVE_REGULATION_OF_PROTEIN_IMPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_IMPORT | 97 | 19 | 15632 | 1249 |
Jak2,Hcls1,Bambi,Il1b,Tlr9,Tlr3,Zc3h12a,Ptgs2,Ddx58,Il18,Sphk1,Tlr2,Il12b,Slc9a1,Il6,Csf3,Rbpms,Tnf,Tnfsf14 |
| 2.099e-04 | -8.47 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN | 97 | 19 | 15632 | 1249 |
Ascc3,Ets2,Cav1,Cyfip1,Tuba4a,Sod2,Gpr68,Pdpn,Carhsp1,Arrdc4,Hif1a,Il1a,Traf3ip2,Cdkn1a,Dusp14,H3f3b,Agpat4,Cdc42ep2,Rras2 |
| 2.102e-04 | -8.47 | GSE4748_LPS_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | MSigDB lists | GSE4748_LPS_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | 154 | 26 | 15632 | 1249 |
Adrb2,Tlr3,Ptger4,Dusp5,Cmklr1,Ccl4,P2ry2,Cep350,Tuba4a,Gch1,Dusp6,Rhou,Pstpip2,Slc2a6,Upp1,Papss2,Slco3a1,Egr1,Pml,Atp2b4,Nod1,Dse,Ankrd17,Mdm2,Tra2a,Vcan |
| 2.104e-04 | -8.47 | GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 129 | 23 | 15632 | 1249 |
Rab3ip,Gys1,Znrf1,Sgk3,Rtp4,Sell,Mpp7,Evl,Aim2,Spint2,Dgka,Treml2,Tnfsf8,Atxn7l1,Myc,Fchsd2,Egr2,Ext1,Mdn1,Rel,Tspan3,Nfkbia,Tnf |
| 2.104e-04 | -8.47 | GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | MSigDB lists | GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | 129 | 23 | 15632 | 1249 |
Phlda1,Zfp36,Cnn3,Gpr132,Ext1,Fosb,Ppp1r15a,Flrt2,Plcl2,Dusp5,Itpkc,Adrb2,Mecp2,Dusp1,Gadd45b,Jun,Fos,Otud1,Gbp2,Slc30a4,Mxd1,Mpp7,Irs2 |
| 2.108e-04 | -8.46 | GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS | MSigDB lists | GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS | 915 | 103 | 15632 | 1249 |
Myc,Sdc2,Kremen1,Chst11,Ezr,Tspan3,Gng11,Pgs1,Atf3,Il4ra,Xrn1,Ccnd2,Met,Ube2e2,Tmem123,Actb,Socs3,Dyrk2,Etnk1,Rcn1,Rhoq,Tbc1d1,Nr3c1,Acvr1,Hsph1,Dusp1,Tank,Rbbp8,Itpr1,Bfar,Clcn5,Calcrl,Spata13,Stx11,Wars,Stoml1,Tuba4a,Map4k4,Jarid2,Slc7a2,Fubp1,Sipa1l1,Ascc3,Daam1,Prkx,Dek,Igf2bp2,Gng12,Smc5,Uchl1,Tor1aip2,Ass1,Psip1,Rnf114,Cited2,Col4a2,Tle3,Bcor,Col18a1,Tpx2,Sdc1,Dcp2,Ppp4r2,Lmo4,Pid1,Rap2c,Cd82,Adam19,Fscn1,Notch2,Rbms1,Wdr43,Asb13,Rnf145,Odc1,Itgb8,Stat3,Dock10,Aebp2,Arhgap26,Errfi1,Txnrd1,Ankrd17,Serp1,Tpst1,Arhgef3,Pbx1,Tnfaip3,Pdgfc,Rgs3,Etv5,F11r,Tab2,Nrp2,Eya4,Csrp1,Dusp6,Cdyl,Atp6v1d,Flrt2,Snn,Psmb6,Phf6 |
| 2.121e-04 | -8.46 | LEE_EARLY_T_LYMPHOCYTE_DN | MSigDB lists | LEE_EARLY_T_LYMPHOCYTE_DN | 60 | 14 | 15632 | 1249 |
Rnaset2b,Samhd1,Tnfsf10,Il4ra,Sema4c,Ptprj,H2-Q7,Klf2,H2-Q6,Rnaset2a,Nlrc5,H2-Q4,Atm,Tuba4a |
| 2.121e-04 | -8.46 | BRUNO_HEMATOPOIESIS | MSigDB lists | BRUNO_HEMATOPOIESIS | 60 | 14 | 15632 | 1249 |
Slfn3,Pbx1,Cd55,Ptgir,Rcn1,Ptgs2,Reps1,Bnip3,Ctsc,Rnf19a,Ccng2,Hk2,Sqstm1,Slfn4 |
| 2.121e-04 | -8.46 | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL | 60 | 14 | 15632 | 1249 |
Cav1,Apobec3,Hivep2,Isg20,Casp3,Irf4,Ell2,Pim2,Dusp5,Prdm1,Tnfaip3,Cd38,Slamf7,Gfpt1 |
| 2.121e-04 | -8.46 | GNF2_TNFRSF1B | MSigDB lists | GNF2_TNFRSF1B | 60 | 14 | 15632 | 1249 |
Hck,Pilra,Myd88,Ms4a6d,Tlr2,Fgr,Nod2,Fgl2,Igsf6,Dusp1,Ccr1,Aoah,Tnfrsf1b,Casp1 |
| 2.126e-04 | -8.46 | embryo development | biological process | GO:0009790 | 1147 | 109 | 20694 | 1406 |
Socs3,Ets2,Lnpk,Phactr4,Vegfc,Tulp3,Plpp3,Hopx,Spic,Slc30a1,Apaf1,Med21,Hdac1,Hinfp,Intu,Acvr1,Il10,Sema4c,Triobp,Edn1,Klf2,Spry2,Fzd5,Pdgfrb,Itga4,Myc,Zeb1,Clic5,Mmp14,Flt1,Mthfr,Mafg,Pdgfb,Lif,Hlx,Lrp4,Bcl2l11,Hsd17b7,Sema3c,Map2k1,Spint2,Foxp4,Flrt3,Bcor,Adar,Maff,Rictor,Sbds,Inhba,Apba1,Mthfd1l,Notch1,Gfi1,Kdr,Cited2,Fzd1,Kitl,Inpp5b,Angpt1,Acvrl1,Prdm1,Ift57,Zfp281,Vezt,Sdc4,Eya4,Casp8,Rbbp8,Phf6,Vcam1,Eno1,Tshz1,Ext1,Notch2,Junb,Plod3,Sec24b,Ifitm1,Rpgrip1l,Kdm6b,Itga5,Acvr1b,Hif1a,Atm,Phgdh,Mgat1,Ttc39c,Abr,Vasp,Lhx2,Nrp2,Bmp2,Casp3,Htr2b,Lmo4,Ptch1,Gja1,Itgav,Cdk5r1,Nr4a3,Keap1,Rcn1,Ahr,Pbx1,Chst11,Atp11a,Pdgfc,Hhex,Txnrd1 |
| 2.129e-04 | -8.45 | Tbk1 (TANK-binding kinase 1) | protein interactions | 56480 | 19 | 8 | 7778 | 753 |
Azi2,Traf3ip2,Ddx58,Tank,Optn,Syk,Irf1,Ikbkg |
| 2.137e-04 | -8.45 | regulation of cellular protein catabolic process | biological process | GO:1903362 | 241 | 32 | 20694 | 1406 |
Cop1,Rnf19b,Trib3,Ptk2,Gclc,Mdm2,Psme1,Rnf139,Trib1,Tnfaip3,Dnajb2,Nupr1,Psmd10,Tmem67,Ezr,Pml,Tlk2,Caml,Ldlr,Ctsc,Sco1,Plk2,N4bp1,Rnf19a,Hspa1b,Plk3,Rnf14,Ankib1,Usp25,Ric1,Psme2,Hspa1a |
| 2.142e-04 | -8.45 | gonad development | biological process | GO:0008406 | 200 | 28 | 20694 | 1406 |
Icam1,Nupr1,Ccnd1,Ahr,Serpine1,Inhba,Gja1,Itgav,Fndc3a,Crkl,Hmga2,Sirt1,Arid5b,Insl6,Tiparp,Serpinb6b,Nos2,Stat5a,Kitl,Arid4a,Kdr,Cited2,Atm,Pla2g4a,Bcl2l11,Angpt1,Src,H3f3b |
| 2.148e-04 | -8.45 | GO_CYTOPLASMIC_SEQUESTERING_OF_PROTEIN | MSigDB lists | GO_CYTOPLASMIC_SEQUESTERING_OF_PROTEIN | 40 | 11 | 15632 | 1249 |
Nfkbib,Tspo,Hk2,Keap1,G3bp2,Nfkbie,Hk1,Nfkbil1,Nfkbia,Psmd10,Il10 |
| 2.148e-04 | -8.45 | SENESE_HDAC2_TARGETS_UP | MSigDB lists | SENESE_HDAC2_TARGETS_UP | 105 | 20 | 15632 | 1249 |
Scyl2,Mmp9,Zc3h12a,Pcgf5,Nfkbiz,Il1a,Ccnd2,Slc16a1,Ppp2r1b,Bcl2a1a,Plau,Tnfaip3,Bcl2a1b,Dpy19l1,Ccnj,Nampt,Dock4,Hmga1,Bcl2a1d,Inhba |
| 2.158e-04 | -8.44 | GSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_UP | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_UP | 180 | 29 | 15632 | 1249 |
Clic4,Rsbn1,5430427O19Rik,Tfec,Dusp28,Cmpk2,Dck,Mmp9,Mthfd2,Lyn,Osgin2,Tlr1,Ahrr,Sesn3,Nos2,Dusp14,Nck1,Slc30a4,Papss2,Dcp2,Setdb2,Stap1,Gpr68,Cxcl14,Rsad2,Cept1,Slc16a3,Crbn,P2ry12 |
| 2.158e-04 | -8.44 | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN | MSigDB lists | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN | 180 | 29 | 15632 | 1249 |
Ccl5,Plek,Tlr3,Sema4a,Adrb2,Map3k8,Ccl4,Gfi1,Cst7,Aoah,H2-Q4,Slc2a1,Rhbdf2,Casz1,Tcf4,Homer1,H2-Q6,Tspan3,Rhoq,Abcb1a,Arhgap26,Palld,H2-Q7,Sphk1,Sertad3,P2ry14,Slamf7,Rras2,Crim1 |
| 2.158e-04 | -8.44 | GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_UP | MSigDB lists | GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_UP | 180 | 29 | 15632 | 1249 |
Pim1,Mob3b,Map3k8,Rab20,Smox,Frmd6,Glrx,Cldnd1,Cnp,Birc3,Gja1,Sesn3,Card6,Fzd1,Sdc1,Il4ra,Dmxl2,Cdkn2d,Mcoln2,Mark2,Crlf3,Timp1,Gpr18,N4bp1,Bcl2l11,Plekhf2,Rin2,Gpr68,Aftph |
| 2.158e-04 | -8.44 | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_UP | 180 | 29 | 15632 | 1249 |
Ift57,Cers6,Cdyl2,Ifi44,Swap70,Itpr1,Tnf,Slfn5,Nlrp3,Tpx2,Cd180,Lrp8,Oas2,Rap1gap2,Oas1a,Usp12,Plscr1,Slc12a9,Birc3,5430427O19Rik,Gcnt2,Chd9,Nsmaf,Cxcl10,Fcho2,Rcan1,Filip1l,Oas1g,Ptk2 |
| 2.188e-04 | -8.43 | regulation of interleukin-10 production | biological process | GO:0032653 | 54 | 12 | 20694 | 1406 |
Lgals9,Il12b,Tnfsf4,Cd274,Cd83,Fcgr2b,Tlr9,Cd34,Irf4,Nod2,Tlr2,Ptger4 |
| 2.188e-04 | -8.43 | regulation of T cell mediated cytotoxicity | biological process | GO:0001914 | 54 | 12 | 20694 | 1406 |
H2-T10,Ripk3,H2-Q7,H2-Q4,Tap2,H2-T22,H2-M2,H2-T24,Nectin2,Il12b,H2-Q6,Pvr |
| 2.202e-04 | -8.42 | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 146 | 25 | 15632 | 1249 |
Oas3,Tcf4,Cx3cr1,Samd9l,Rsad2,Ggct,Tbc1d1,Ddx60,Itga4,Mdfic,Zc3hav1,Nod1,Lcn2,Ifit3,Oas2,Tmem176a,Xaf1,Oas1a,Ifit3b,Asb13,Oas1g,Oasl1,Vrk2,Sp110,Clcf1 |
| 2.205e-04 | -8.42 | GO_REGULATION_OF_ORGANELLE_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 1066 | 117 | 15632 | 1249 |
Bnip3,Pla2g4a,Stap1,Mid1,Sqstm1,Nlrc4,Hmga1,Kif9,Sdc4,Tspo,Nck1,Evl,Bcor,Stxbp1,Nek6,Kat2b,Sdc1,Tpx2,Mul1,Cdk5r1,Pikfyve,Slc9a1,Rictor,Rhou,Atm,S100a8,Jdp2,Cav1,Pid1,Cenpj,Casp8,Fscn1,Whamm,Fam162a,Ptk2,Mmp9,Lpar1,Rab20,Micall2,Tlk2,Mecp2,Tnf,Phldb1,Ddhd1,Bcl6,Plagl2,Parp10,Asap3,F11r,Vasp,Tbc1d13,Plek,Myadm,Fzd5,Pdgfrb,Map2k1,Osm,Il1b,Parp3,Cdc42ep4,Spire1,Edn1,Myc,Prkce,Triobp,Cenpe,Ezr,Sbds,Bcl2l11,Psmd10,Cyfip1,Cdc42ep2,Chmp4b,Mark2,Pttg1,Phip,Sirt1,Birc3,Rnf31,Tmem67,Hcls1,Kdr,Asf1a,Stard7,Gfi1,Tmod3,Adrb2,Tbc1d1,Rhoq,Dync1h1,Src,Dusp1,Rgs14,Swap70,Birc2,Gpsm2,Daxx,Hck,Lif,Pml,Mthfr,Il1a,Hif1a,Icam1,Kdm4a,Pdgfb,Csf3,Hap1,Jarid2,Plk2,Clic4,Tnfsf10,Plaur,Sec24b,Prdm9,Ptger4,Smc5 |
| 2.206e-04 | -8.42 | GO_MACROPHAGE_ACTIVATION | MSigDB lists | GO_MACROPHAGE_ACTIVATION | 28 | 9 | 15632 | 1249 |
Prkce,Tlr1,Jun,Jmjd6,Cx3cl1,Slc7a2,Cx3cr1,Tlr3,Syk |
| 2.206e-04 | -8.42 | SHIN_B_CELL_LYMPHOMA_CLUSTER_3 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_3 | 28 | 9 | 15632 | 1249 |
Nfkb2,Jak2,Fzd1,Ccnd1,Nfkb1,Hhex,Il18,Fgr,Cd86 |
| 2.206e-04 | -8.42 | BIOCARTA_FAS_PATHWAY | MSigDB lists | BIOCARTA_FAS_PATHWAY | 28 | 9 | 15632 | 1249 |
Ripk2,Casp7,Fas,Map2k4,Casp8,Jun,Cflar,Casp3,Daxx |
| 2.206e-04 | -8.42 | ABE_VEGFA_TARGETS_2HR | MSigDB lists | ABE_VEGFA_TARGETS_2HR | 28 | 9 | 15632 | 1249 |
Nr4a1,Lad1,Upp1,Rcan1,Ptgs2,Serpinb2,Ldlr,Cdkn1a,Tnfrsf14 |
| 2.206e-04 | -8.42 | GO_NEGATIVE_REGULATION_OF_T_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_T_CELL_DIFFERENTIATION | 28 | 9 | 15632 | 1249 |
Ifnb1,Nfkbid,Ptpn2,Bcl6,Il4ra,Cd74,Irf1,Tnfsf4,Hlx |
| 2.213e-04 | -8.42 | BROWNE_HCMV_INFECTION_48HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_48HR_UP | 163 | 27 | 15632 | 1249 |
Itpr1,Gpr18,Lrp4,Gadd45b,Ezr,Hspa2,Pcx,Ggct,Atp11a,Calcrl,Atf3,Zc3hav1,Gem,Ccne1,Pdk3,Hat1,Eef1e1,Slc39a14,Slpi,Sap30,Ier3,Gpd2,Cd55,Ptges,Bambi,Ppp2r1b,Snapc1 |
| 2.215e-04 | -8.42 | skeletal muscle organ development | biological process | GO:0060538 | 151 | 23 | 20694 | 1406 |
Homer1,Flnb,Egr1,Nupr1,Maff,Cav1,Myc,Btg2,Notch1,Hivep3,Rcan1,Egr2,Cited2,Psma6,Plagl1,Hlx,Bcl9,Sap30,Cflar,Fos,Met,Nr4a1,Atf3 |
| 2.215e-04 | -8.42 | GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_DN | MSigDB lists | GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_DN | 189 | 30 | 15632 | 1249 |
Igsf9,Ccne1,Plk2,Flnb,Parp3,Dtx2,Denr,Odc1,Cxcl10,Notch2,Pmepa1,Nfkbia,Ehd1,Srm,Sqstm1,Ass1,Traf2,Tmem184b,Trip10,Igsf6,Cish,Egr2,Ccdc86,Nfkbie,Ift57,Rars,Ier2,Ccnd2,Gmppb,Gng11 |
| 2.215e-04 | -8.42 | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN | 189 | 30 | 15632 | 1249 |
Myc,Atp13a1,Nfkbia,Dusp1,Klf6,Tnf,Spryd7,Psmb9,Hspa1a,Psme1,Evl,Egr1,Tlr6,Usp18,Sell,Socs1,Gbe1,Il4ra,Psmb10,Zfp36,Ppp1r15a,Fosb,Lmo4,Tnip1,Dnajb2,Larp1,Pim2,Socs3,Ldha,Phyh |
| 2.215e-04 | -8.42 | GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | 189 | 30 | 15632 | 1249 |
Slfn8,Edn1,Dhx58,Atp13a1,Vcan,Ifit2,Zyx,Csf3r,Cd14,Zbp1,Myd88,Pilra,Ripk3,Atf3,Psmb10,Socs1,Tifa,Pou2f2,Oas2,Slamf9,Clec4n,Adap2,Ogfr,Ifit3,Slfn9,Glrx,Hmox1,Socs3,Fam53c,Ifit3b |
| 2.216e-04 | -8.41 | TNF_dom | interpro domains | IPR006052 | 19 | 7 | 19984 | 1430 |
Tnfsf10,Tnfsf15,Tnfsf4,Tnfsf14,Tnf,Tnfsf9,Tnfsf8 |
| 2.235e-04 | -8.41 | Intestinal immune network for IgA production | KEGG pathways | mmu04672 | 42 | 12 | 7931 | 713 |
Itga4,Icosl,Cd40,Il10,Cd80,H2-Aa,Il15ra,Cd86,H2-Eb1,Il15,H2-Ab1,Il6 |
| 2.235e-04 | -8.41 | Intestinal immune network for IgA production | KEGG pathways | ko04672 | 42 | 12 | 7931 | 713 |
Itga4,Cd86,Icosl,Il10,Cd80,Il15ra,H2-Aa,H2-Ab1,Il6,Cd40,H2-Eb1,Il15 |
| 2.242e-04 | -8.40 | heat shock protein binding | molecular function | GO:0031072 | 139 | 22 | 20217 | 1400 |
Dnaja2,Ahr,Nod2,Nr3c1,Pttg1,Zfp36,Stip1,Hspa2,Nfkbia,Eno1,Bcor,Ksr1,Spn,Nos2,Hspa1a,Apaf1,Hif1a,Nfkb1,Hspa1b,Ahsa1,Dnaja1,Dnajb2 |
| 2.242e-04 | -8.40 | mouse chr1|1 H3 | chromosome location | mouse chr1|1 H3 | 69 | 13 | 24173 | 1464 |
Slamf9,Slamf8,Ifi209,Nectin4,Aim2,Kmo,Ifi211,Ifi214,Hsd17b7,Ifi208,Ifi213,Slamf7,Ifi207 |
| 2.257e-04 | -8.40 | GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP | 198 | 31 | 15632 | 1249 |
Slc44a1,Dock10,Psd,Ifnar1,Parp8,Nfkbia,H2-Q4,Mgat1,H2-Q6,B4galt4,Spred1,H2-Q7,Nlrp3,Plagl1,Prnp,Pdgfb,Icosl,Jarid2,Tnfsf10,Tnfaip2,Rgs1,Lrp11,Arf4,Dnajb2,Dio2,Smox,Ebi3,St7,Pim1,Trib1,Odc1 |
| 2.263e-04 | -8.39 | SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER | MSigDB lists | SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER | 34 | 10 | 15632 | 1249 |
Stat3,Trp53i11,Bnip3,Cdc42ep2,Csf3,Lhx2,Ezr,Uchl1,F11r,Ddx4 |
| 2.263e-04 | -8.39 | PACHER_TARGETS_OF_IGF1_AND_IGF2_UP | MSigDB lists | PACHER_TARGETS_OF_IGF1_AND_IGF2_UP | 34 | 10 | 15632 | 1249 |
Mid1,Ifrd1,Slc7a5,Phgdh,Asns,Slc7a11,Gdf15,Ass1,Egr3,Mfap3l |
| 2.263e-04 | -8.39 | VALK_AML_CLUSTER_11 | MSigDB lists | VALK_AML_CLUSTER_11 | 34 | 10 | 15632 | 1249 |
Serpinb9,Cd200,Ass1,Evl,Mdfic,Cish,Clic4,St3gal5,Cd34,Ciita |
| 2.263e-04 | -8.39 | MARZEC_IL2_SIGNALING_DN | MSigDB lists | MARZEC_IL2_SIGNALING_DN | 34 | 10 | 15632 | 1249 |
Ccng2,Pdgfc,Rffl,Pde3b,Jak2,Card6,Sesn3,Casp1,Fas,Atm |
| 2.267e-04 | -8.39 | OSMAN_BLADDER_CANCER_UP | MSigDB lists | OSMAN_BLADDER_CANCER_UP | 365 | 49 | 15632 | 1249 |
Rsbn1,Sec24a,Ldha,Ripk2,Usp42,Rab10,Sap30,Stxbp3,Vasp,Brwd3,Klf2,Atp6v1d,1600014C10Rik,Irak3,Zfp319,Il1a,Fam133b,Agtrap,Rhoq,Tapbp,Slc25a37,Ankrd17,Eno1,Rbms1,Chd9,Mtdh,Kpna3,Tmod3,Azi2,Zc3h7a,Plscr1,Kctd12,Lnpep,Il15,Enpp4,Atp11b,Samhd1,Nfkbiz,Sgms2,Prnp,Gbe1,Ctsc,Gclm,Pla2g4a,Slc44a1,Bbx,4932438A13Rik,I830077J02Rik,Cited2 |
| 2.283e-04 | -8.38 | protein localization to extracellular region | biological process | GO:0071692 | 161 | 24 | 20694 | 1406 |
Aim2,Nos2,Mcoln2,Trem1,Plek,Nod2,Lyn,Notch2,Tlr2,Rab10,Nlrc4,Itgav,Lcp2,Tlr6,Stxbp3,Rnf19b,Isg15,Notch1,Nlrp3,Il1rn,Traf3ip2,Pou2f2,Svbp,Optn |
| 2.292e-04 | -8.38 | HALLMARK_COAGULATION | MSigDB lists | HALLMARK_COAGULATION | 138 | 24 | 15632 | 1249 |
Timp1,Mmp14,C1ra,F10,Plau,Dusp14,Olr1,Klf7,Gda,Dusp6,Csrp1,Plek,Serpine1,Htra1,Pdgfb,Maff,C3,Mmp9,Plat,Thbs1,Serpinb2,Arf4,Pf4,Gng12 |
| 2.298e-04 | -8.38 | regulation of cell-substrate adhesion | biological process | GO:0010810 | 211 | 29 | 20694 | 1406 |
Bst1,Itga5,Kdr,Vegfc,Plekha2,Jag1,Pdpn,Src,Gcnt2,Plau,Acvrl1,Map4k4,Thbs1,Sdc4,Ptprj,Jak2,Triobp,Crkl,Prkce,Myadm,Csf1,Serpine1,Carmil1,Bcl6,Hsd17b12,Notch1,Rac3,Mmp14,Ptk2 |
| 2.301e-04 | -8.38 | T cell costimulation | biological process | GO:0031295 | 26 | 8 | 20694 | 1406 |
Cd274,Tnfsf4,Tnfsf14,Cd86,Tnfrsf14,Cav1,Cd80,Spn |
| 2.301e-04 | -8.38 | positive regulation of activated T cell proliferation | biological process | GO:0042104 | 26 | 8 | 20694 | 1406 |
Il12rb1,Stat5a,Il12b,Cd86,Tnfsf4,Tnfsf9,Il18,Icosl |
| 2.304e-04 | -8.38 | GSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_UP | MSigDB lists | GSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_UP | 172 | 28 | 15632 | 1249 |
Spry2,Aftph,Gpr18,Homer1,D16Ertd472e,Agrn,Il4ra,Ier2,Irf2,Ddx60,Abr,Egr1,Samsn1,Hsd17b12,Junb,Gch1,Rnf31,Hcls1,Rap2c,Tnip1,Acvr1b,Mppe1,Ier3,Arid5b,Kif3c,Etnk1,Slc31a1,Pim2 |
| 2.304e-04 | -8.38 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_UP | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_UP | 172 | 28 | 15632 | 1249 |
Rasgrp1,Jag1,Csrp1,Ccne1,Birc3,Sipa1l1,Asns,Daam1,Adam19,Nfil3,Endod1,Lyn,Fchsd2,Irf4,Sp140,Apobec3,Swap70,Gpr18,Sla,Cd83,Hck,Samhd1,Rhoh,Abr,Il4ra,Arl4a,Cd180,Kmo |
| 2.304e-04 | -8.38 | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN | MSigDB lists | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN | 172 | 28 | 15632 | 1249 |
Fmnl2,Agpat4,Ell2,Mmp9,Kif5c,Ptprj,Shisa3,Grina,Phlpp2,Snx2,Eno2,Fzd5,Il10,Sco1,Ciita,Irak3,Stxbp1,Dmxl2,Fut8,Abcb1a,Nqo1,Stk40,Gpr68,Optn,Apobec3,Ehd1,Dusp1,Ttc39c |
| 2.305e-04 | -8.38 | Apoptosis Modulation by HSP70 | WikiPathways | WP166 | 17 | 8 | 4813 | 540 |
Hspa1a,Fas,Apaf1,Nfkb1,Casp8,Casp7,Casp2,Casp3 |
| 2.323e-04 | -8.37 | regulation of receptor biosynthetic process | biological process | GO:0010869 | 20 | 7 | 20694 | 1406 |
Itgav,Edn1,Jak2,Hif1a,Hdac1,Sec24a,Nr1h3 |
| 2.323e-04 | -8.37 | positive regulation of tumor necrosis factor biosynthetic process | biological process | GO:0042535 | 20 | 7 | 20694 | 1406 |
Tlr1,Tlr2,Tnfrsf8,Mapkapk2,Jak2,Spn,Thbs1 |
| 2.323e-04 | -8.37 | regulation of macrophage differentiation | biological process | GO:0045649 | 20 | 7 | 20694 | 1406 |
Casp8,Trib1,Csf1,Hcls1,Lif,Pf4,Ptpn2 |
| 2.323e-04 | -8.37 | negative regulation of myeloid cell apoptotic process | biological process | GO:0033033 | 20 | 7 | 20694 | 1406 |
Clec5a,Ccl5,Fcgr2b,Il18,Kitl,Stat5a,Nod2 |
| 2.323e-04 | -8.37 | leukocyte adhesion to vascular endothelial cell | biological process | GO:0061756 | 20 | 7 | 20694 | 1406 |
Sele,Spn,Cx3cr1,Sell,Itga4,Vcam1,Tnf |
| 2.323e-04 | -8.37 | response to muramyl dipeptide | biological process | GO:0032495 | 20 | 7 | 20694 | 1406 |
Nfkbia,Tnfaip3,Ripk2,Nod2,Nod1,Jag1,Notch1 |
| 2.327e-04 | -8.37 | regulation of cell morphogenesis | biological process | GO:0022604 | 519 | 57 | 20694 | 1406 |
Sdc2,Ccl12,Ezr,Brwd3,Rab21,Cdc42ep4,Met,Ccl2,Ust,Fmnl2,Ccl3,Zswim4,Rhou,Pdpn,Bambi,Kdr,Mov10,Mecp2,Rac3,Rnd1,Rhoc,Agrn,Prag1,Mark2,Ptk2,Myo10,Icam1,Lrp8,Carmil1,Sema4c,Rhoq,Triobp,Sipa1l1,Phip,Ifrd1,Fgr,Map2k1,Eif4g2,Sema4a,Lst1,Src,Cdc42ep2,Hck,Rapgef2,Sema3c,Mul1,Lpar1,Lrp4,Cyfip1,Il6,Rhoh,Cdk5r1,Myadm,Rnd3,Rhof,Crkl,Dbnl |
| 2.327e-04 | -8.37 | EIF4E_DN | MSigDB lists | EIF4E_DN | 90 | 18 | 15632 | 1249 |
Uba7,Ctsc,Ep400,Sik3,Stat5a,Parp8,Plekha5,Ncoa7,Myo10,Snapc1,Plau,Tnip1,Ptgs2,Phip,Fas,Cd55,Mmp9,C3 |
| 2.329e-04 | -8.36 | chemokine binding | molecular function | GO:0019956 | 32 | 9 | 20217 | 1400 |
Cx3cr1,Itga4,Zfp36,Xcr1,Ccrl2,Pdpn,Ccr3,Ccr1,Itgav |
| 2.331e-04 | -8.36 | Znf_B-box | interpro domains | IPR000315 | 67 | 14 | 19984 | 1430 |
Mefv,Trim34a,Trim13,Trim12c,Mid1,Trim30d,Trim14,Trim30a,Trim36,Trim26,Pml,Trim21,Trim56,Trim12a |
| 2.337e-04 | -8.36 | SERVITJA_ISLET_HNF1A_TARGETS_UP | MSigDB lists | SERVITJA_ISLET_HNF1A_TARGETS_UP | 155 | 26 | 15632 | 1249 |
Fabp7,Csf1,Procr,Htra1,H2-Aa,Vcam1,Notch2,Tnfaip2,Egr3,Uchl1,Parp3,Pla2g4a,Ctsc,Mmp14,Egr2,Slc15a3,Ifit2,Cnn2,Ccl12,Ass1,Slc16a1,Rhoc,Atf3,Col18a1,Sdc1,Gbp3 |
| 2.348e-04 | -8.36 | cell cycle phase transition | biological process | GO:0044770 | 142 | 22 | 20694 | 1406 |
Chmp4b,Acvr1,Ccnj,Hinfp,Pim2,Cdkn1a,Ccne1,Rbbp8,Plk2,Timeless,Gpr132,Rhou,Plk3,Ccnd1,Rgcc,Crlf3,Ccng2,Inhba,Cdkn2d,Ccnd2,Acvr1b,Abcb1a |
| 2.348e-04 | -8.36 | RNA catabolic process | biological process | GO:0006401 | 142 | 22 | 20694 | 1406 |
Pnpt1,Magohb,Atm,Tent4a,Rnaset2a,Ago3,Smg7,Isg20,Noct,Gtpbp2,Slfn8,Dcp2,Tut7,Zhx2,Xrn1,Helz2,Tent2,Polr2g,Zfp36,Dcp1a,Zc3h12a,Oas2 |
| 2.356e-04 | -8.35 | positive regulation of protein polymerization | biological process | GO:0032273 | 114 | 19 | 20694 | 1406 |
Rictor,Carmil1,Vasp,Fchsd2,Cav1,Icam1,Prkce,Spire1,Mecp2,Cyfip1,Gda,Rac3,Evl,Nck1,Csf3,Cdc42ep2,Cdc42ep4,Met,Whamm |
| 2.365e-04 | -8.35 | lysosome | cellular component | GO:0005764 | 428 | 49 | 20747 | 1409 |
Rnf19b,Sqstm1,Gja1,Tnfaip3,Cst7,Acp5,Calcrl,Il1b,Clcn7,Cd74,Acpp,Hck,Mt1,Pdgfrb,Mmp13,H2-Aa,Ldlr,Slc15a3,Rab9,Mcoln2,Cd164,Rnaset2b,Wdr59,Slc49a4,Zc3hav1,Ass1,Src,Slc30a4,Milr1,Ifnar1,Ctsc,Snx2,Tlr9,Treml4,Hap1,H2-Eb1,Znrf1,Cd34,Acp2,Dtx3l,Slc29a3,Rnaset2a,Srgn,Il4i1,Trip10,Irgm1,Dram1,Slc48a1,P2ry2 |
| 2.367e-04 | -8.35 | GSE43863_NAIVE_VS_TFH_CD4_EFF_TCELL_D6_LCMV_DN | MSigDB lists | GSE43863_NAIVE_VS_TFH_CD4_EFF_TCELL_D6_LCMV_DN | 130 | 23 | 15632 | 1249 |
Parp14,Batf2,Il18bp,Taf4b,Optn,Nod2,Gadd45b,Tnf,Nlrc5,Gch1,Cst7,Ccl5,Irf8,Msr1,Gna15,Casp8,Fosb,Tnfaip2,Inpp1,Trafd1,Rhoh,Nupr1,Stat2 |
| 2.368e-04 | -8.35 | ZF_RING_2 | prosite domains | PS50089 | 268 | 38 | 13278 | 1037 |
Rnf19b,Rnf135,Rnf114,Ankib1,Trim12c,Rnf24,Cnot4,Traf5,Rnf139,Trim26,Traf2,Znrf1,Rnf145,Birc3,Rnf34,Trim12a,Trim36,Birc2,Znrf3,Pcgf5,Cop1,Mid1,Trim30d,Trim34a,Trim30a,Dtx2,Bfar,Mul1,Nfxl1,Rnf14,Trim21,Trim13,Rffl,Dtx3l,Rnf19a,Pml,Trim56,Mdm2 |
| 2.375e-04 | -8.35 | cellular nitrogen compound catabolic process | biological process | GO:0044270 | 274 | 35 | 20694 | 1406 |
Tut7,Slfn8,Dcp2,Gtpbp2,Noct,Isg20,Cnp,Smg7,Samhd1,Ago3,Rnaset2a,Upp1,Hdc,Tent4a,Atm,Apobec3,Magohb,Pnpt1,Mgat1,Pde5a,Oas2,Dnase1l3,Zc3h12a,Dcp1a,Zfp36,Tet2,Gda,Polr2g,Kmo,Enpp4,Tent2,Helz2,Xrn1,Zhx2,Hmox1 |
| 2.375e-04 | -8.35 | erythrocyte homeostasis | biological process | GO:0034101 | 105 | 18 | 20694 | 1406 |
Axl,Ampd3,Hcls1,Prdx1,Bcl6,Ikzf1,Ptpn2,Jmjd6,Lyn,Hmox1,Tmod3,Adar,Klf2,Tcea1,Cited2,Arid4a,Casp3,Jak2 |
| 2.378e-04 | -8.34 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_DN | 181 | 29 | 15632 | 1249 |
Atp6v1d,Irf8,Akt3,Rab20,Nr4a3,Ptafr,Ttc39b,Lpar1,Il1b,Pmepa1,Tagap,Tnfsf10,Acpp,Gpr18,Mtus1,Arid5a,Spsb1,Cpd,Gpr68,Nfkbie,Rin2,Batf2,Tnfsf8,Slc39a4,Ctsc,Nek6,Rhoc,Ahr,Cd38 |
| 2.378e-04 | -8.34 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_UP | 181 | 29 | 15632 | 1249 |
Timp1,Bcl2l11,Ccl12,Parp9,Samd9l,Dusp2,Arg2,Nxf1,Fas,Plk3,Slc28a2,Ppfibp1,Gnb4,Mov10,Plk2,Slfn4,Klf2,Casp4,Igsf9,Junb,Psd4,Bst1,Rtn1,Glrx,Ptges,Slfn3,Rbms1,Ccl4,Slc29a3 |
| 2.378e-04 | -8.34 | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_DN | MSigDB lists | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_DN | 181 | 29 | 15632 | 1249 |
Orai2,Cdkn1a,Rcn1,Serpinb9,Frmd4a,Psme2,Timeless,Stat4,Il18rap,Dgka,Ifit1bl2,Dcun1d3,Extl2,1600014C10Rik,Rgs3,Crim1,Ddx60,Psme1,Evl,Cyth3,Spata13,Slco3a1,Ppp2r5a,Peli1,Gsr,Cnn2,Ifit1bl1,Pik3r5,Eno1 |
| 2.378e-04 | -8.34 | GSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_UP | 181 | 29 | 15632 | 1249 |
Timp1,Casp1,Ass1,Bcl2l11,Scarf1,Samd9l,Phlpp1,Dusp2,Sertad3,Mxd1,Plk3,Itga4,Gbp2,Hopx,Mov10,Gdf15,Egln3,Rasgrp1,Dgka,Bst1,Tifa,Ube2l6,Ms4a6d,Filip1l,Tnfsf4,Glrx,Prkar2b,Fam162a,Ccl4 |
| 2.378e-04 | -8.34 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN | 181 | 29 | 15632 | 1249 |
Slfn8,Gpr35,Peli1,Trmt1l,Sav1,Apba1,Stat2,Phlpp2,Tifa,Flnb,Stoml1,Kctd12,Rgl1,Nfkb1,Itgal,Actb,Irak2,Tnip1,Chd9,Cldnd1,Slfn9,Epsti1,Vegfc,Ap3m2,Ptk2,Sema4c,Dusp5,Tmod3,Irf1 |
| 2.378e-04 | -8.34 | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN | MSigDB lists | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN | 181 | 29 | 15632 | 1249 |
Arl5b,Csf1,Cxcl2,AA467197,Kctd12,Nfkb1,Myadm,Ccr1,Notch2,Cdkn1a,Dusp16,Mmp9,Ptgir,Filip1l,Ptger4,Acvr1b,Pim1,Il6,Cish,Fgl2,N4bp1,Plac8,Swap70,Ahr,Rhoc,Aff1,Ppm1l,Kat2b,Prnp |
| 2.378e-04 | -8.34 | GSE27786_LIN_NEG_VS_NKCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_NKCELL_DN | 181 | 29 | 15632 | 1249 |
Ccdc88b,Zfp281,Icam1,Mapkapk2,Mthfr,Cept1,Cnot4,Cxcl14,Parp9,Gpr68,Ikzf1,Slfn8,Stard5,Rgs14,Dync1h1,Cmklr1,Slfn9,Cd300lf,Asb13,Ifi35,Stat1,Smc5,Ptgir,Rtn1,Usp12,Inhba,Leng9,Zc3h7a,Sap30 |
| 2.378e-04 | -8.34 | GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_DN | MSigDB lists | GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_DN | 181 | 29 | 15632 | 1249 |
Fut8,Tnfsf8,Aoah,Ifit1bl1,Apobec3,Gclc,Prpf4,Magohb,Mcm10,Fpr2,Aldh1b1,Sell,Trim12c,Nlrp3,Tpx2,Gpr132,Antxr1,Bst1,Ifit1bl2,Card6,Sesn3,Ltbp2,Pid1,Cmklr1,Tnfsf10,Ptger4,Il13ra1,Fpr1,Rcsd1 |
| 2.378e-04 | -8.34 | GSE27786_ERYTHROBLAST_VS_MONO_MAC_DN | MSigDB lists | GSE27786_ERYTHROBLAST_VS_MONO_MAC_DN | 181 | 29 | 15632 | 1249 |
Mdn1,Gpr35,Mllt6,Ogfrl1,Ythdf1,N4bp1,Arhgef3,Gpc1,Pbx1,Atp11b,Slc28a2,Tlr6,Agtrap,Psmb10,Trim14,Zfp36,Pdss1,Stat4,Nampt,Lnpep,Tshz1,Sipa1l1,Heatr6,Casp8,Znrf1,Ikbke,Sec24b,Wdr43,Ttc39b |
| 2.382e-04 | -8.34 | macromolecule localization | biological process | GO:0033036 | 2211 | 191 | 20694 | 1406 |
Pikfyve,Cdkn1a,Abcc1,Katna1,Pla2g4a,Etv5,Ift57,Serp1,Rtn2,Stra6l,Magohb,Rffl,Atp6v1d,Egr2,Slc28a2,Agrn,Txn1,Il1rn,Traf3ip2,Plod3,Bcl6,Ppp1r15a,Tor1aip2,Notch2,Calcrl,Srgn,Rab10,Stxbp3,Rrbp1,Grk3,Cacnb3,Trem1,Plek,Atp11b,Mcm9,Mid1,Ap3m2,Pgap2,G3bp2,Isg15,Il1b,Mdm2,Slc15a3,Keap1,Psmd10,Hk2,Itgav,Rtp4,D1Ertd622e,Ezr,Arrdc4,Nfkbia,Stard5,Gbp2,Stat5a,Pnpt1,Ap3b1,Tulp3,Mecp2,Kif5c,Rab3ip,Rnf19b,Htr2a,Vps54,Dcp1a,Dennd1b,Tor1aip1,Stx6,Snx10,4932438A13Rik,Sec24a,Nxf1,Treml4,Stat3,Aftph,Arl4a,Gramd1a,Nlrp3,Ranbp2,Pou2f2,Abcc4,Optn,Apba1,Inhba,Tnfaip3,Adar,Mpp7,Rab19,Slco3a1,Nlrc4,Tlr6,Lcp2,Pml,Arl5c,Angpt1,Ikzf1,Rab20,Fcho2,Snx2,Daxx,Tnf,Syk,Osbpl3,Sh3bp4,Ric1,Stxbp1,Cd74,Parp3,Fabp3,Tnfaip2,Tbc1d1,Ift22,Lipg,Hk1,Rabgef1,Nlgn2,Arl5b,Phip,Igf2bp2,Msr1,Dennd2a,Stoml1,Rapgef2,Rab9,Plscr1,Syne2,Stard7,Cox18,Kpna3,Atm,Acsl1,Acsl5,Lgals9,Tap1,Hhex,Arf4,Atp11a,Chst11,Lyn,Cav1,Spire1,Parp11,Myadm,Tbc1d13,Rab32,Sqstm1,Ptch1,F11r,Pdzd11,Rab21,Xkr8,Hinfp,Ehd1,Tspo,Fchsd2,Rab11fip1,Aim2,Mcoln2,Abcb1a,Cenpe,Morc3,Clic5,Svbp,Itga4,Dtx3l,Zfp36,Nod2,Frmd6,Tmsb10,Tap2,Dnaja1,Stau1,Homer1,Hap1,Stx11,Rrs1,Ldlr,Myo1b,Lrp4,Rhbdf2,Nos2,Atp10a,Rilpl1,Plekhf2,Notch1,Chmp4b,Tomm70a,Itgal,Fam53c,Tlr2,Nfkbib |
| 2.400e-04 | -8.33 | negative regulation of proteolysis | biological process | GO:0045861 | 361 | 43 | 20694 | 1406 |
Spint2,Timp1,Prdx5,Plat,Tnfsf14,Mmp9,Mdm2,Serpinb9b,Slpi,Il6,Usp25,Serpinb6b,Ptgs2,Serpina3f,Bcl2a1d,Cflar,Src,Hspa1b,N4bp1,Thbs1,Tlk2,Birc2,Trim21,Serpinb2,Serpinb9,Dnajb2,Cdkn2d,Serpine1,Ctla2a,Nr1h3,C3,Cst7,Rnf34,Adora2a,Serpina3g,Rffl,Nr4a1,Sco1,Caml,Plaur,Il10,Pml,Birc3 |
| 2.416e-04 | -8.33 | GO_NATURAL_KILLER_CELL_ACTIVATION | MSigDB lists | GO_NATURAL_KILLER_CELL_ACTIVATION | 47 | 12 | 15632 | 1249 |
Il12b,Il18,Pik3cd,Slamf7,Il15,Ifna1,Ifna2,Axl,Casp8,Ifna6,Ifna5,Ifnb1 |
| 2.434e-04 | -8.32 | GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN | MSigDB lists | GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN | 190 | 30 | 15632 | 1249 |
Odc1,Tmem229b,Map3k8,Socs3,Cd200,Epsti1,Nfil3,Rbms1,Cnp,Casp4,Stoml1,Kctd12,Tyk2,Syne2,Cysltr2,Il4ra,Sell,Evl,Enpp4,Dnase1l3,Mdfic,Rnd3,Gpc1,Arid5a,Gpr18,Casz1,Bcl2l11,Cept1,Micall2,Tnfsf8 |
| 2.438e-04 | -8.32 | zinc ion binding | molecular function | GO:0008270 | 672 | 71 | 20217 | 1400 |
Slfn9,Mefv,Trafd1,Trim21,Znfx1,Apobec3,Trim14,Egr1,Rasgrp1,Tcea1,Asah2,Mdm2,Dhx58,Trim36,Rnf145,Mt2,Top3a,Traf1,Trim13,Mmp25,Samhd1,Nr3c1,Zcchc2,Zswim4,Ddx58,Slfn8,Mid1,Timp1,Trim34a,Cpd,Rnf24,Ifih1,Setdb2,Trim12a,Sec24b,Mmp14,Pikfyve,Pml,Traf2,Tet2,Birc2,Mmp13,Sec24a,Ubr4,Tnfaip3,Tnfsf10,Trim56,Tut7,Smpdl3b,Gch1,Trim26,Nr1h3,Kdm4a,S100a8,Nr4a1,Mmp9,Dtnb,Morc3,Mt1,Dtx2,Lnpep,Gda,Ptch1,Traf5,Sqstm1,Rnf139,Trim30a,Rabgef1,Kdm5b,Nr4a3,Car13 |
| 2.444e-04 | -8.32 | GO_LYTIC_VACUOLE | MSigDB lists | GO_LYTIC_VACUOLE | 474 | 60 | 15632 | 1249 |
Tlr3,Rnf19b,H2-Ab1,Nr4a3,Slc29a3,Acp2,Il1b,Gja1,H2-Eb1,Atp6v1d,Pdgfrb,Rnaset2a,H2-Aa,Hap1,Mmp13,Vasn,Slc30a4,Cd74,Calcrl,Atp11a,Gnb4,Tnfaip3,Hck,Clcn5,Cd164,Ifnar1,Src,Acpp,Slc15a3,Rffl,Cp,Rab9,Tlr9,Dram1,Lyn,Pik3cd,Adrb2,Ldlr,Znrf1,Clcn7,Rnaset2b,Lnpep,P2ry2,Rasgrp1,Mmd,Sdc1,Gpc1,Slc48a1,Cd34,Sdc4,Zc3hav1,Sqstm1,Agrn,Ass1,Trip10,Il4i1,Ctsc,Sdc2,Vcan,Ap3b1 |
| 2.446e-04 | -8.32 | positive regulation of JUN kinase activity | biological process | GO:0043507 | 79 | 15 | 20694 | 1406 |
Il1rn,Il1b,Map2k4,Fzd5,Mlkl,Tlr9,Mapkbp1,Tnf,Mdfic,Ripk2,Mul1,Traf2,Tlr6,Edn1,Syk |
| 2.451e-04 | -8.31 | negative regulation of adaptive immune response | biological process | GO:0002820 | 47 | 11 | 20694 | 1406 |
Zc3h12a,Samsn1,Spn,Bcl6,Tnfsf4,Fcgr2b,Nod2,Il4ra,Ifnb1,Parp3,Tnfrsf14 |
| 2.451e-04 | -8.31 | positive regulation of epithelial to mesenchymal transition | biological process | GO:0010718 | 47 | 11 | 20694 | 1406 |
Rgcc,Notch1,Jag1,Pdpn,Il1b,Acvr1,Bmp2,Glipr2,Gcnt2,Bambi,Il6 |
| 2.451e-04 | -8.31 | regulation of cell aging | biological process | GO:0090342 | 47 | 11 | 20694 | 1406 |
Bcl6,Plk2,Rbl1,Eef1e1,Sirt1,Arg2,Akt3,Nampt,Cgas,Hmga2,Pnpt1 |
| 2.451e-04 | -8.31 | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 164 | 27 | 15632 | 1249 |
Syne2,Ifit3,Sema3c,Mppe1,Ifit3b,Pik3cd,Mmp25,Max,Herc6,Fgl2,Sdc2,Samd9l,Ggct,Gclm,Spic,Ifit2,Plekha5,Abcc5,Zc3hav1,Crlf3,Pde3b,Adar,Ddx58,Sell,Dtx3l,Hhex,Itga4 |
| 2.451e-04 | -8.31 | BROWNE_HCMV_INFECTION_18HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_18HR_UP | 164 | 27 | 15632 | 1249 |
Gsr,Katna1,Abcc5,Nfkbia,Morc3,Tap1,Tle3,Etv5,Enpp4,Smg7,Cd83,Il15,Dcp2,Casp2,Rasgrp1,Met,Stx6,Eya4,Med13,Zhx2,Sec24a,Ldlr,Rsbn1,Il1rn,Mthfd2,Lyn,St7 |
| 2.456e-04 | -8.31 | GSE40274_CTRL_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 147 | 25 | 15632 | 1249 |
Rbbp8,Znfx1,Rai14,Mul1,Mpp7,Prrg4,Ddx60,Spred1,Slamf7,Tmc3,Prdx1,Batf,Cd83,Lad1,Itgal,Hk2,Cd69,Smpdl3b,Nmi,Trim21,Serpinb9,Ifi35,Nfil3,Lrp11,Cflar |
| 2.463e-04 | -8.31 | GO_RESPONSE_TO_METAL_ION | MSigDB lists | GO_RESPONSE_TO_METAL_ION | 309 | 43 | 15632 | 1249 |
C3,S100a8,Nfkb1,Cav1,Casp8,Fas,Sdc1,Prnp,Slc30a1,Tspo,Ass1,Fos,Jun,Pla2g4a,Edn1,Bnip3,Il6,Hmox1,Ptgs2,Vcam1,Thbs1,Clic4,Ptges,Keap1,Junb,Cd86,Fosb,Slc25a12,Slc30a4,Hif1a,Icam1,Il1a,Sphk1,Cd14,Daxx,Hvcn1,Dusp1,Homer1,Casp3,Cp,Ccnd1,Mecp2,Mdm2 |
| 2.469e-04 | -8.31 | mitotic cell cycle phase transition | biological process | GO:0044772 | 133 | 21 | 20694 | 1406 |
Ccng2,Crlf3,Inhba,Cdkn2d,Plk3,Rhou,Ccnd1,Rgcc,Abcb1a,Ccnd2,Acvr1b,Cdkn1a,Ccne1,Rbbp8,Ccnj,Chmp4b,Acvr1,Hinfp,Pim2,Plk2,Gpr132 |
| 2.473e-04 | -8.30 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_UP | 199 | 31 | 15632 | 1249 |
Spry2,Prkce,Errfi1,Cd200r4,Chst11,Bcl2a1d,H2-Q4,Casp1,Bcl2a1b,H2-Q6,Tal2,Gpc1,Samhd1,H2-Q7,Atf3,Prdm1,Traf1,Piezo1,Spint2,4930523C07Rik,Ccl5,Hopx,Asns,Cd86,Bcl2a1a,Rgs1,Plat,5430427O19Rik,Nfil3,Kif5c,Slc25a22 |
| 2.481e-04 | -8.30 | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP | 68 | 15 | 15632 | 1249 |
Thbs1,Armc8,Dusp16,Egr1,Ell2,Cpeb4,Serpinb9,Cp,Rapgef2,Slc39a14,Nampt,Fosb,Ets2,Sik3,Tnfsf14 |
| 2.481e-04 | -8.30 | GO_ENDOTHELIAL_CELL_DIFFERENTIATION | MSigDB lists | GO_ENDOTHELIAL_CELL_DIFFERENTIATION | 68 | 15 | 15632 | 1249 |
Kdm6b,Col18a1,Icam1,F11r,Clic4,Rap2c,Notch1,Ezr,Plod3,Myadm,Acvr1,Jag1,Rapgef2,Acvrl1,Met |
| 2.489e-04 | -8.30 | anchoring junction | cellular component | GO:0070161 | 307 | 38 | 20747 | 1409 |
Dst,Ptk2,Pdlim7,Itga5,Keap1,Nectin2,Gja1,Itgb8,Asap3,Ezr,Flnb,Map2k1,Zyx,Itgav,Vasp,Evl,Mpp7,Pkp4,Irf2,Frmd4a,Nectin4,Tnks1bp1,Jak2,Jag1,Cyth3,Pvr,Flrt3,Hck,Flrt2,Cdc42ep4,Prag1,Notch1,Rnd1,Sdc4,Lyn,Syne2,Map4k4,Cav1 |
| 2.499e-04 | -8.29 | lytic vacuole | cellular component | GO:0000323 | 429 | 49 | 20747 | 1409 |
Clcn7,Il1b,Cd74,Acpp,Acp5,Calcrl,Gja1,Sqstm1,Rnf19b,Tnfaip3,Cst7,Wdr59,Rnaset2b,Slc49a4,Zc3hav1,Mcoln2,Cd164,Mt1,Pdgfrb,Hck,Ldlr,H2-Aa,Mmp13,Slc15a3,Rab9,Hap1,Tlr9,Treml4,Slc30a4,Ifnar1,Milr1,Ctsc,Snx2,Ass1,Src,Dram1,Slc48a1,P2ry2,Irgm1,Trip10,Acp2,Rnaset2a,Srgn,Slc29a3,Dtx3l,Il4i1,H2-Eb1,Znrf1,Cd34 |
| 2.541e-04 | -8.28 | MODULE_433 | MSigDB lists | MODULE_433 | 54 | 13 | 15632 | 1249 |
Osm,Nampt,Lif,Inhba,Vegfc,Jag1,Csf3,Il15,Csf1,Pdgfb,Bmp2,Tnfsf10,Il6 |
| 2.544e-04 | -8.28 | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 173 | 28 | 15632 | 1249 |
Tlr1,Zfp36,Syne2,Slc12a9,Atm,Junb,Fcgr4,Dusp6,Card6,Casp8,Notch2,Jak2,Adam19,Tmem219,Rab11fip1,Ly75,Treml2,Arhgap26,Dusp1,Cx3cr1,Lpcat2,Tspo,Hk3,Apaf1,Mvp,Hhex,Prrg4,Rnf135 |
| 2.544e-04 | -8.28 | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | MSigDB lists | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | 173 | 28 | 15632 | 1249 |
Slc39a14,Isg20,Ext1,Plod2,Cenpj,Lcp2,Csrp1,Eno2,Gng12,Ppa1,Mmp9,Ptgir,Kdm6b,Smox,Phactr4,Ift57,Ncoa5,Egr2,Eno1,Homer1,Spsb1,Samhd1,Tle3,Ncoa7,Gnb4,Rtp4,Spata13,Egr1 |
| 2.544e-04 | -8.28 | GSE360_CTRL_VS_L_MAJOR_MAC_DN | MSigDB lists | GSE360_CTRL_VS_L_MAJOR_MAC_DN | 173 | 28 | 15632 | 1249 |
Optn,Gadd45g,Nqo1,Gsr,Top3a,Homer1,Birc2,Psip1,Ahr,Plagl2,Mdfic,Traf5,Zbtb5,Myd88,Slc30a4,G3bp2,Slc13a3,Ccne1,Gch1,Igf1r,Pgk1,Abcc4,Tfec,Clic4,Inpp1,Rgs1,Acsl1,Ell2 |
| 2.544e-04 | -8.28 | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_UP | MSigDB lists | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_UP | 173 | 28 | 15632 | 1249 |
Myo10,Tnfrsf14,Enpp4,Bmp2,Sgk3,Traf5,Ciita,Nr1h3,Pikfyve,Malt1,Evl,Cept1,Mecp2,Cd40,Itpr1,Lrp4,Psip1,Cnn2,Clic4,Serpinb2,Acsl5,Slc43a3,Rcn1,Tifa,Akt3,Inpp5b,Marco,Slc4a7 |
| 2.553e-04 | -8.27 | GO_POSITIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION | 83 | 17 | 15632 | 1249 |
Ripk2,Lif,Ifna1,Hcls1,Atp2b4,Ifna2,Angpt1,Txn1,Tnf,Cav1,Osm,Spry2,Ifna6,Il6,Csf3,Ifna5,Ifnb1 |
| 2.553e-04 | -8.27 | GO_PYRUVATE_METABOLIC_PROCESS | MSigDB lists | GO_PYRUVATE_METABOLIC_PROCESS | 61 | 14 | 15632 | 1249 |
Nr4a3,Ldha,Tpi1,Pgk1,Pfkl,Hk3,Slc16a1,Pfkfb3,Eno1,Hk1,Slc16a3,Eno2,Pcx,Hk2 |
| 2.553e-04 | -8.27 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN | 61 | 14 | 15632 | 1249 |
Bbx,Phlda1,Ddit4,Dusp4,Kctd12,Ccl12,Tcf4,Itpr1,Plk2,Ccl4,Olfml3,Glrx,Atp2b4,Larp1 |
| 2.557e-04 | -8.27 | plasma membrane raft | cellular component | GO:0044853 | 124 | 20 | 20747 | 1409 |
Lipe,Ptch1,Ptgs2,Igf1r,Adrb2,Cav1,Sele,Lrp8,Ezr,Hmox1,Hck,Hk1,Lcp2,Ldlr,Slc2a1,Jak2,Asah2,P2ry12,Lrp4,Src |
| 2.578e-04 | -8.26 | GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | MSigDB lists | GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 699 | 82 | 15632 | 1249 |
Myadm,Gja1,Plek,Flrt2,Plk2,Fzd5,Piezo1,Tbc1d13,Hap1,Vasp,Csf3,Rapgef2,Ptger4,Ptprj,Nsmaf,Spire1,Cdc42ep4,Thbs1,Sec24b,Phldb1,Src,Tnf,Hspa1a,Birc2,Swap70,Rhoq,Tbc1d1,Hspa2,Acvrl1,Mecp2,Asap3,Aim2,Parp10,Icam1,Hck,Myo10,Notch1,Atm,Lmo4,Cenpj,Irf8,Cav1,Slc9a1,Xaf1,Rictor,Tmod3,Ptk2,Rab20,Mefv,Lpar1,Kdr,Hcls1,Whamm,Fscn1,Nlgn2,Pmepa1,Dnajb2,Flrt3,Bcl2l11,Agrn,Crbn,Eif2ak2,Ezr,Jun,Cyfip1,Prkce,Mmp14,Stap1,Edn1,Triobp,Tlr6,Stxbp1,Evl,Nck1,Fas,Pikfyve,Mpp7,Sdc1,Cdc42ep2,Kif9,Sdc4,Chmp4b |
| 2.588e-04 | -8.26 | actin filament bundle organization | biological process | GO:0061572 | 71 | 14 | 20694 | 1406 |
Marcks,Rhof,Triobp,Dbnl,Spire1,Rnd3,Src,Myo1b,Swap70,Fscn1,Rhoc,Rnd1,Ezr,Zyx |
| 2.588e-04 | -8.26 | regulation of cardiac muscle hypertrophy | biological process | GO:0010611 | 71 | 14 | 20694 | 1406 |
Nr4a3,Edn1,Errfi1,Atp2b4,Notch1,Trip10,Ptk2,Jarid2,Tnfrsf1b,Sirt1,Slc9a1,Tomm70a,Pde5a,Nr3c1 |
| 2.610e-04 | -8.25 | response to cadmium ion | biological process | GO:0046686 | 33 | 9 | 20694 | 1406 |
Jun,Fos,Mt2,Daxx,Hmox1,Mt1,Slc30a1,Prnp,Mmp9 |
| 2.617e-04 | -8.25 | GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 182 | 29 | 15632 | 1249 |
Gclc,Tnfaip3,Psme1,Ube2e1,Plk3,Rnf139,Psmb10,Ctsc,Mdm2,Psma6,Ezr,Rnf114,Psmb9,Psmd10,Keap1,Dnajb2,Ptk2,Rnf19b,Smc5,Psmb6,Trib1,Trib3,Psme2,Rnf19a,Psmb8,Ankib1,Rnf14,Cav1,Plk2 |
| 2.617e-04 | -8.25 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN | 182 | 29 | 15632 | 1249 |
Psip1,Slc25a37,Fam43a,Ikzf1,Gpr68,Errfi1,Ch25h,Traf1,Cd180,Pde3b,Crlf3,Sdc4,Sav1,Tle3,Atp11b,Klf7,Card6,Ccl5,Junb,Hopx,Phlpp2,Snx2,Dyrk2,Acvr1b,Irak2,Prkx,Whamm,Dnajb2,Dusp16 |
| 2.617e-04 | -8.25 | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_DN | MSigDB lists | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_DN | 182 | 29 | 15632 | 1249 |
Swap70,Fam43a,Cdyl2,Cebpd,Abcb1a,Slc44a1,Nmral1,Traf1,Malt1,Hlx,Aim2,Apaf1,Samhd1,Nod1,Cd80,Birc3,Akt3,Slc2a6,Trip13,Tlr1,Plscr1,St3gal5,Rcan1,Casp7,Acp2,Fscn1,Gca,Serpinb2,Tmem123 |
| 2.617e-04 | -8.25 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN | 182 | 29 | 15632 | 1249 |
Ccne1,Rgl1,Xaf1,Cd69,Pla2g7,Trim56,Filip1l,Ripk2,Dyrk2,Lyn,Fam111a,Tnip1,Slfn9,Pilrb1,Rcl1,Clmp,Cst7,Rnf114,Fam43a,Crbn,Mtus1,Cyfip1,Tet2,Slfn8,Rsad2,Nfkbie,St3gal6,Ifih1,Pilrb2 |
| 2.617e-04 | -8.25 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN | 182 | 29 | 15632 | 1249 |
Ly75,Mdn1,Casp1,Dusp1,Cd40,Homer1,Il15,Batf,Mdfic,Tnks1bp1,Bcor,Abr,Dmxl2,Znrf3,Dtwd1,Slpi,Trim21,Ksr1,Rap1gap2,Nampt,Casp4,Mcm9,Daam1,Gca,Sh3bgrl2,Cacna1d,Stat1,Ttc39b,Mob3b |
| 2.617e-04 | -8.25 | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP | 182 | 29 | 15632 | 1249 |
Nfkbie,Fgl2,Mllt6,Samd9l,Rsad2,Bcl2a1d,Ifnar1,Bcl2a1b,Kif9,Klf7,Clcn5,Ier2,Sdc1,Calcrl,Bcl9,Procr,Akt3,Med13,Usp12,Etv6,Xaf1,Junb,Tnfrsf1b,Gbp7,Bcl2a1a,Tax1bp1,Dyrk2,Socs3,Azi2 |
| 2.617e-04 | -8.25 | GSE39022_LN_VS_SPLEEN_DC_UP | MSigDB lists | GSE39022_LN_VS_SPLEEN_DC_UP | 182 | 29 | 15632 | 1249 |
Ehd1,D1Ertd622e,Phgdh,Pnp2,Cox17,Aebp2,Mxd1,Prdm1,Tpi1,Tlr6,Upp1,Ncoa7,Chmp4b,Relb,Angpt1,Tuba4a,Marco,Csf1,Nmi,Rapgef2,Il18rap,Slc43a3,Sema4a,Acsl5,Osbpl3,Idi1,Agpat4,Lhx2,Cmpk2 |
| 2.617e-04 | -8.25 | GSE3039_CD4_TCELL_VS_B2_BCELL_DN | MSigDB lists | GSE3039_CD4_TCELL_VS_B2_BCELL_DN | 182 | 29 | 15632 | 1249 |
Tnip1,Ccl4,Serpinb2,Igf2bp2,Plaur,Acp2,Ptk2,Ppa1,Odc1,Ier3,Nr4a3,Nrp2,Wars,Smpdl3b,Cd274,Fcgr1,Lipg,Cd38,Spred1,Trim13,Ccnd2,Gpr84,Rhoq,Txnrd1,Ass1,Serp1,Eno1,Cd302,Dock4 |
| 2.617e-04 | -8.25 | GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_UP | MSigDB lists | GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_UP | 182 | 29 | 15632 | 1249 |
Armc8,Ap3m2,Slfn3,Tmem123,Cacnb3,Pik3cd,Ccdc25,Rictor,Tyk2,Leng9,Tdrd7,Ampd3,Slfn4,Cnp,Arid4a,Vcpip1,Ube2f,Cd180,Dcp2,Papss2,Mpp7,Evl,Ogfrl1,Parp14,Rbbp8,Bcl6,Parp8,Dpy19l1,Plac8 |
| 2.617e-04 | -8.25 | GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP | MSigDB lists | GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP | 182 | 29 | 15632 | 1249 |
Sell,Arl4a,P2ry14,Hlx,Gnb4,Trp53i11,Traf5,Pde3b,Lpcat2,Hivep2,Parp8,Cnn2,Ap3b1,Ccng2,Rhoq,Grina,Ms4a6d,Dck,Gtpbp2,Thbs1,Tmem123,Lnpep,Ccrl2,Pla2g7,Dgka,Uba7,Icosl,Akt3,Tlr1 |
| 2.617e-04 | -8.25 | GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_DN | 182 | 29 | 15632 | 1249 |
Esd,Tnfaip2,Asf1a,Polr2g,Clcn7,Acsl5,Vcam1,Acsl1,Fpr1,Sema4a,Gpr85,Cd200,Prdm9,Pou2f2,Parp12,Rasgrp1,Bst1,Myo1b,Nfkb1,Jdp2,Rsad2,Aebp2,Mdm2,Tlk2,Tspan3,Psmd10,Arhgef3,Itgav,Gramd1a |
| 2.621e-04 | -8.25 | negative regulation of leukocyte migration | biological process | GO:0002686 | 40 | 10 | 20694 | 1406 |
Ccl12,Gpr18,Cd200,Rabgef1,Abr,Lrch1,Dusp1,Stap1,Ptger4,Slamf8 |
| 2.621e-04 | -8.25 | positive regulation of myeloid leukocyte mediated immunity | biological process | GO:0002888 | 40 | 10 | 20694 | 1406 |
Ddx58,Cxcl1,Il4ra,C3,Adora2b,Ptafr,Stxbp1,Syk,Fgr,Fcgr1 |
| 2.645e-04 | -8.24 | V-set | pfam domains | PF07686 | 163 | 25 | 18711 | 1348 |
Pvr,Siglece,Treml4,Igsf8,Cd83,F11r,Vcan,Cd80,Trem1,Cd200r4,Gm5150,Tapbpl,B430306N03Rik,Cd300e,Scn1b,Cd86,Cd274,Treml2,A530064D06Rik,Icosl,Clmp,Nectin2,Slamf9,Nectin4,Cd300lf |
| 2.646e-04 | -8.24 | MHC_I/II-like_Ag-recog | interpro domains | IPR011162 | 60 | 13 | 19984 | 1430 |
H2-Eb1,Procr,H2-T10,Raet1e,H2-T22,H2-Aa,H2-M2,H2-T24,H2-Q7,H2-Q4,H2-Q6,H60b,H2-Ab1 |
| 2.669e-04 | -8.23 | positive regulation of endothelial cell migration | biological process | GO:0010595 | 97 | 17 | 20694 | 1406 |
Adora2b,Akt3,Plk2,Thbs1,Zc3h12a,Met,Sirt1,Angpt1,Stat5a,Ptgs2,Hmox1,Plpp3,Vegfc,Cd40,Pdgfb,Kdr,Hif1a |
| 2.671e-04 | -8.23 | GO_RESPONSE_TO_NUTRIENT | MSigDB lists | GO_RESPONSE_TO_NUTRIENT | 191 | 30 | 15632 | 1249 |
Apaf1,Lipg,Tspo,Slc16a1,Il15,Mthfr,Cdkn2d,Nqo1,Ccnd1,Mdm2,Cp,Tnc,Pla2g4a,Ccl12,Ass1,Eif2ak2,Il1b,Vcam1,Cxcl10,Acsl1,Pim1,Ptgs2,Ldha,Hmox1,Hmgcs1,Hat1,Fzd1,Cav1,Ccne1,Ccl5 |
| 2.680e-04 | -8.22 | DAZARD_UV_RESPONSE_CLUSTER_G2 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G2 | 23 | 8 | 15632 | 1249 |
Cited2,Ier3,Csrp1,Atf3,Junb,Cxcl2,Bambi,Cxcl1 |
| 2.696e-04 | -8.22 | GO_INTRINSIC_COMPONENT_OF_PLASMA_MEMBRANE | MSigDB lists | GO_INTRINSIC_COMPONENT_OF_PLASMA_MEMBRANE | 1488 | 155 | 15632 | 1249 |
Gpr68,Itgb8,Cp,Ntng2,Slc39a4,Tnfsf8,Traf2,H2-Q6,P2ry13,Csf3r,Tnf,Abcc5,Slc16a3,Hvcn1,Traf5,Cd14,Rapgef2,Il12rb1,H2-Aa,Flrt2,Pdgfrb,Ccr1,Gja1,Htr2b,Pcdh7,Pilrb1,Adora2b,Il2rg,Tlr3,Slc31a1,Mmp14,Spn,Itgav,Olr1,Sgcb,F10,Pilrb2,Sdc4,Cd34,Pilra,Il15,Slc16a1,Gpc1,Sdc1,P2ry14,Znrf3,Fas,Mmd,Slc9a1,Cav1,Tnfrsf1b,Ednrb,Abcc1,Lrrc8c,Notch2,Ldlr,Cd82,Lpar1,Itga9,Lyn,Ptgir,Itga5,Acvr1,Acvrl1,Atp13a1,Gpr84,Ly75,P2ry12,Birc2,Cd40,Slc2a1,Axl,Gypc,Ifnar1,Clcn5,Cd164,Bfar,Cd83,Tnfrsf8,Bmp2,Calcrl,Cd180,Icam1,Slco3a1,Sell,Itga4,H2-Q7,Adora2a,Slc2a6,Tlr1,Slc7a5,Scn1b,Tnfsf15,Slc7a2,Slc13a3,Slc7a8,Slc31a2,Slc4a7,Plaur,Dcbld2,Cmklr1,Tnfsf10,Kcna3,Clec5a,Ptafr,Ptprj,Cd55,Prokr1,Kcnj2,Ccr3,Il6,Pdpn,Igsf6,Gpr35,Msr1,Tspan3,Zyx,Cx3cr1,H2-Q4,Flt1,Flrt3,Slc7a11,Tnfrsf14,Atp2b4,Slc28a2,Htr2a,Sgms2,Il4ra,Tlr6,Jag1,Ccrl2,Slc39a14,Met,Cd69,Cysltr2,Procr,Plscr1,St3gal5,Itgal,Marco,P2ry2,Rnf31,Lnpep,Igf1r,Xcr1,Nlgn2,Siglece,Kdr,Acvr1b,Tlr2,Adrb2,Tnfsf4,Nox1,Cd200,Il13ra1 |
| 2.700e-04 | -8.22 | HASINA_NOL7_TARGETS_DN | MSigDB lists | HASINA_NOL7_TARGETS_DN | 13 | 6 | 15632 | 1249 |
Sdc1,Cd55,Jag1,Sdc2,Met,Angpt1 |
| 2.700e-04 | -8.22 | BIOCARTA_GRANULOCYTES_PATHWAY | MSigDB lists | BIOCARTA_GRANULOCYTES_PATHWAY | 13 | 6 | 15632 | 1249 |
Tnf,Csf3,Itgal,Il1a,Icam1,Sell |
| 2.700e-04 | -8.22 | GO_POSITIVE_REGULATION_OF_MONOCYTE_CHEMOTAXIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_MONOCYTE_CHEMOTAXIS | 13 | 6 | 15632 | 1249 |
Ccl5,Ccl12,Ccr1,Serpine1,Cxcl10,Pla2g7 |
| 2.700e-04 | -8.22 | PID_TCR_JNK_PATHWAY | MSigDB lists | PID_TCR_JNK_PATHWAY | 13 | 6 | 15632 | 1249 |
Dbnl,Lcp2,Jun,Map3k8,Map2k4,Crkl |
| 2.700e-04 | -8.22 | GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION | 13 | 6 | 15632 | 1249 |
Mefv,Irak3,Il10,Nfkb1,Thbs1,Cmklr1 |
| 2.700e-04 | -8.22 | GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | 13 | 6 | 15632 | 1249 |
Ptger4,Adrb2,Dock4,Ptgs2,Adora2b,Calcrl |
| 2.700e-04 | -8.22 | MODULE_178 | MSigDB lists | MODULE_178 | 13 | 6 | 15632 | 1249 |
Il18,Kdr,Tnfaip2,Vegfc,Jag1,Angpt1 |
| 2.700e-04 | -8.22 | GO_REGULATION_OF_VIRAL_INDUCED_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_VIRAL_INDUCED_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 13 | 6 | 15632 | 1249 |
Zc3hav1,Dhx58,Ddx60,Birc3,Birc2,Ankrd17 |
| 2.703e-04 | -8.22 | Ras protein signal transduction | biological process | GO:0007265 | 213 | 29 | 20694 | 1406 |
Rac3,Rhoh,Rhoc,Rnd1,Gpsm2,Ift22,Bcl6,Rab10,Rnd3,Rhof,Rhoq,Rab32,Rab19,Dbnl,Rras2,Rap2c,Rab21,Cdc42ep2,Rab9,Cdc42ep4,Rab20,Plk2,Rapgef2,Rhou,Pdpn,Ksr1,Jun,Phactr4,Cyfip1 |
| 2.709e-04 | -8.21 | AML_Q6 | MSigDB lists | AML_Q6 | 236 | 35 | 15632 | 1249 |
Trib1,Phf6,Sema4a,Mafg,Rnf19b,Mmp9,Agpat4,Gfi1,Rgs1,Cav1,Ptch1,Ccr1,Cdyl,Vasn,Cd69,Il18rap,Rilpl1,Pigv,Nlrp3,Hlx,Nek6,Lif,Rbl1,Batf,Smg7,Sla,Pbx1,Bcl6,Dusp1,Flt1,Nr4a1,Ccl12,B3gnt5,Prokr1,Dusp2 |
| 2.713e-04 | -8.21 | GSE2585_THYMIC_MACROPHAGE_VS_MTEC_DN | MSigDB lists | GSE2585_THYMIC_MACROPHAGE_VS_MTEC_DN | 165 | 27 | 15632 | 1249 |
Ccl4,Pmepa1,Nfil3,Cdkn1a,Slc43a3,Pim1,Arid5b,Nr4a3,Rab20,Isg20,Ddit4,Bcl9,Il18rap,Pde4b,Hk1,Atp2b4,Plagl2,Lif,Dmxl2,Bnip3,Rnf24,Mecp2,Pde5a,Slc7a11,Msr1,Tcf4,Jun |
| 2.713e-04 | -8.21 | GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | MSigDB lists | GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | 165 | 27 | 15632 | 1249 |
Notch1,Rhoh,Irs2,Zfp281,Ccdc86,Myc,Ythdf1,Ifrd1,Bcl2l11,Crbn,Parp8,Znfx1,Tagap,Zc3h12a,Scyl2,Max,Fam53c,Trib1,Zfp36,Gpr132,Cd69,Nfkbid,Zfp324,Gem,Fosb,Rel,Tnfsf14 |
| 2.713e-04 | -8.21 | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_2H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_2H_UP | 165 | 27 | 15632 | 1249 |
Gch1,Tnfrsf1b,Ccne1,Slc2a6,St3gal5,Rictor,Slc25a12,Sema4c,C3,Hmox1,Arid5b,Ust,Cenpe,Tnf,Rhof,Sat1,Ctsc,Cdyl2,Evl,Nfkbiz,Itga4,Slc39a13,Ubash3b,Slamf7,Tnfrsf8,Spred1,Plagl2 |
| 2.713e-04 | -8.21 | positive regulation of T-helper 17 type immune response | biological process | GO:2000318 | 10 | 5 | 20694 | 1406 |
Nfkbid,Nfkbiz,Nlrp3,Malt1,Arid5a |
| 2.713e-04 | -8.21 | negative regulation of type I interferon-mediated signaling pathway | biological process | GO:0060339 | 10 | 5 | 20694 | 1406 |
Ptpn2,Samhd1,Adar,Mul1,Nlrc5 |
| 2.713e-04 | -8.21 | cell proliferation involved in kidney development | biological process | GO:0072111 | 10 | 5 | 20694 | 1406 |
Bmp2,Egr1,Ptch1,Pdgfrb,Pdgfb |
| 2.713e-04 | -8.21 | regulation of neutrophil apoptotic process | biological process | GO:0033029 | 10 | 5 | 20694 | 1406 |
Pik3cd,Slc7a11,Fcgr2b,Hcar2,Il18 |
| 2.713e-04 | -8.21 | interleukin-6 production | biological process | GO:0032635 | 10 | 5 | 20694 | 1406 |
Nos2,Il1b,Il18rap,Il18,Azi2 |
| 2.713e-04 | -8.21 | regulation of fever generation | biological process | GO:0031620 | 10 | 5 | 20694 | 1406 |
Il1b,Tnf,Ptgs2,Ccl5,Ednrb |
| 2.713e-04 | -8.21 | negative regulation of tumor necrosis factor secretion | biological process | GO:1904468 | 10 | 5 | 20694 | 1406 |
Ptger4,Arg2,Cx3cl1,Zc3h12a,Tlr6 |
| 2.713e-04 | -8.21 | type I interferon production | biological process | GO:0032606 | 10 | 5 | 20694 | 1406 |
Trim56,Azi2,Irf7,Ifnar1,Myd88 |
| 2.725e-04 | -8.21 | MANTOVANI_NFKB_TARGETS_UP | MSigDB lists | MANTOVANI_NFKB_TARGETS_UP | 41 | 11 | 15632 | 1249 |
Dusp6,Ccl12,Flt1,Casp4,Il10,Cp,Prkce,Myc,C3,Nfkbiz,Vcam1 |
| 2.725e-04 | -8.21 | PID_UPA_UPAR_PATHWAY | MSigDB lists | PID_UPA_UPAR_PATHWAY | 41 | 11 | 15632 | 1249 |
Serpine1,Pdgfrb,Itgav,Src,Mmp13,Fpr1,Fpr2,Mmp9,Itga5,Plaur,Plau |
| 2.744e-04 | -8.20 | receptor-mediated endocytosis | biological process | GO:0006898 | 134 | 21 | 20694 | 1406 |
Calcrl,Fcho2,Fchsd2,Cav1,Reps1,Dbnl,Syk,Msr1,Htr2b,Marco,Fpr2,Ezr,Ldlr,Scarf1,Fcgr2b,Scyl2,Itga4,Fcgr1,Grk3,Adrb2,Cd14 |
| 2.761e-04 | -8.19 | Activation of caspases through apoptosome-mediated cleavage | REACTOME pathways | R-MMU-111459 | 5 | 4 | 8608 | 757 |
Apaf1,Cycs,Casp3,Casp7 |
| 2.761e-04 | -8.19 | Cytochrome c-mediated apoptotic response | REACTOME pathways | R-MMU-111461 | 5 | 4 | 8608 | 757 |
Cycs,Apaf1,Casp7,Casp3 |
| 2.778e-04 | -8.19 | IRF_2 | prosite domains | PS51507 | 9 | 5 | 13278 | 1037 |
Irf7,Irf8,Irf4,Irf1,Irf2 |
| 2.778e-04 | -8.19 | IRF_1 | prosite domains | PS00601 | 9 | 5 | 13278 | 1037 |
Irf8,Irf7,Irf1,Irf2,Irf4 |
| 2.780e-04 | -8.19 | GO_GROWTH_FACTOR_BINDING | MSigDB lists | GO_GROWTH_FACTOR_BINDING | 115 | 21 | 15632 | 1249 |
Rhbdf2,Pdgfrb,Itgav,Ltbp2,Flt1,Dusp1,Acvrl1,Hap1,Vasn,Acvr1,Htra1,Pdgfb,Nrp2,Il2rg,Acvr1b,Igf1r,Crim1,Kdr,Gpc1,Thbs1,Il1rn |
| 2.780e-04 | -8.19 | DAZARD_RESPONSE_TO_UV_SCC_DN | MSigDB lists | DAZARD_RESPONSE_TO_UV_SCC_DN | 115 | 21 | 15632 | 1249 |
Il4ra,Adora2b,Crkl,Tnfaip3,Klf7,Casp8,Tiparp,Rrs1,N4bp1,Jarid2,Morc3,Cdyl,Dusp4,Rap1gap2,Cnot4,Rapgef2,Tlk2,Myc,Sat1,Ext1,Ddit4 |
| 2.791e-04 | -8.18 | regulation of developmental growth | biological process | GO:0048638 | 397 | 46 | 20694 | 1406 |
Sirt1,Plac8,Tomm70a,Hmga2,Ppp2r3a,Notch1,Trip10,Ptch1,Gja1,Dbnl,Pim1,Ahr,Cdk5r1,Stat3,Bcl2l11,Sema3c,Nr3c1,Eif4g2,Jarid2,Sema4a,Cyfip1,Mul1,Hlx,Gdf15,Sav1,Agrn,Ptk2,C3,Edn1,Sema4c,Ifrd1,Csf1,Serpine1,Serp1,Ikzf1,Adrb2,Cdkn1a,Rab21,Ezr,Dusp6,Mecp2,Cited2,Ptger4,Hopx,Daxx,Stat5a |
| 2.800e-04 | -8.18 | Chemokine receptors bind chemokines | REACTOME pathways | R-MMU-380108 | 50 | 13 | 8608 | 757 |
Pf4,Ccr3,Cxcl10,Ccrl2,Cxcl1,Cxcl11,Cxcl3,Ccl5,Xcr1,Cxcl9,Cx3cl1,Cxcl2,Cx3cr1 |
| 2.802e-04 | -8.18 | BRLZ | smart domains | SM00338 | 51 | 13 | 9567 | 823 |
Fos,Fosb,Jdp2,Nfil3,Mafk,Jun,Mafg,Batf,Batf2,Atf3,Maff,Cebpd,Junb |
| 2.806e-04 | -8.18 | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN | 174 | 28 | 15632 | 1249 |
Slc2a1,Tcf4,Tspan3,Ppp1r14b,Slc7a11,Cers6,Lztfl1,Fchsd2,Irf4,Mdn1,Rhoh,Mapkapk2,Mdfic,Dnase1l3,Crim1,Cd164,Irf8,Higd1a,Dach1,Spint2,Slc7a5,Flnb,Zeb1,Odc1,Dusp5,Dck,Zhx2,Adam19 |
| 2.806e-04 | -8.18 | GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_DN | MSigDB lists | GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_DN | 174 | 28 | 15632 | 1249 |
Gtpbp2,Trib3,Cd200,Ell2,Inpp5b,Bcorl1,Isg20,Asah2,Sik3,Plekha2,Gbp7,Clic5,Slc7a8,Atp2b4,Ifit1,Mvp,Zfp319,Irak3,Rbms2,Upp1,Traf1,Ifih1,Nfkbiz,Pml,Stxbp1,Phlpp1,Optn,Gramd1a |
| 2.810e-04 | -8.18 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP | 292 | 41 | 15632 | 1249 |
Sesn3,C1rl,Gbgt1,Tlr1,Ampd3,Plscr1,Pstpip2,Caml,Rhou,Xaf1,Traf3ip2,Cpeb4,Mthfd2,Il18,Mefv,Tnfaip2,Cd300lf,Nfkb2,Glrx,Prkar2b,Slc7a11,Casp1,Csf3r,Tet2,Nlrc4,Pde1b,Sat1,Parp9,Tra2a,Fgl2,4932438A13Rik,Mcoln2,Stxbp1,Prdm1,Parp10,Dmxl2,Ifih1,Kdm4a,F11r,Cd74,Stat2 |
| 2.812e-04 | -8.18 | GO_EPITHELIUM_DEVELOPMENT | MSigDB lists | GO_EPITHELIUM_DEVELOPMENT | 869 | 98 | 15632 | 1249 |
Phgdh,Tnc,Errfi1,Hdac1,Plod3,Sav1,Pbx1,Apaf1,Prdm1,Tulp3,F11r,Arg2,Rab10,Rapgef2,Inhba,Vasp,Ppp2r3a,Fzd1,Myadm,Gja1,Fzd5,Map2k1,Pgk1,Mmp14,Ift57,Phactr4,Dhrs9,Cited2,Cd34,Sdc4,Palld,Col18a1,Sdc1,Csf1,Cnn3,Tdrd7,Atm,Ednrb,Sema3c,Lmo4,Rpgrip1l,Jak2,Rap2c,Lhx2,Cdkn1a,Frmd6,Sema4c,Itga5,Casp3,Setdb2,Ccnd1,Acvr1,Kdm5b,Acvrl1,Src,Lrp4,Gpsm2,Bmp2,Notch1,Rhoc,Hhex,Pml,Hif1a,Icam1,Intu,Pdgfb,Rilpl1,Slc4a7,Arid4a,Mthfd1l,Klf2,Prkx,Clic4,Vegfc,Sec24b,Kdm6b,Fndc3a,Spry2,Edn1,Myc,Il6,Ezr,Flrt3,Slc7a11,Tagln,Jun,Timeless,Flnb,Jag1,Met,Clic5,Il10,Ptch1,Fam20c,Kdr,Socs3,Stat1,Acvr1b |
| 2.844e-04 | -8.17 | death-inducing signaling complex | cellular component | GO:0031264 | 6 | 4 | 20747 | 1409 |
Casp3,Cflar,Fas,Casp8 |
| 2.848e-04 | -8.16 | positive regulation of T-helper 17 cell differentiation | biological process | GO:2000321 | 6 | 4 | 20694 | 1406 |
Nfkbid,Nfkbiz,Nlrp3,Malt1 |
| 2.848e-04 | -8.16 | T cell extravasation | biological process | GO:0072683 | 6 | 4 | 20694 | 1406 |
Icam1,Ccl2,Ccl5,Crkl |
| 2.848e-04 | -8.16 | cellular response to bacterial lipopeptide | biological process | GO:0071221 | 6 | 4 | 20694 | 1406 |
Tlr6,Tlr1,Cd14,Tlr2 |
| 2.848e-04 | -8.16 | response to hyperoxia | biological process | GO:0055093 | 6 | 4 | 20694 | 1406 |
Fas,Nox1,Cav1,Sod2 |
| 2.848e-04 | -8.16 | cytokine secretion involved in immune response | biological process | GO:0002374 | 6 | 4 | 20694 | 1406 |
Nlrp3,Tlr2,Trem1,Nod2 |
| 2.848e-04 | -8.16 | cellular response to peptidoglycan | biological process | GO:0071224 | 6 | 4 | 20694 | 1406 |
Tlr2,Nlrp3,Nod2,Ripk2 |
| 2.848e-04 | -8.16 | interferon-gamma-mediated signaling pathway | biological process | GO:0060333 | 6 | 4 | 20694 | 1406 |
Irf1,Jak2,Nmi,Stat1 |
| 2.848e-04 | -8.16 | glomerular mesangium development | biological process | GO:0072109 | 6 | 4 | 20694 | 1406 |
Pdgfrb,Egr1,Notch1,Pdgfb |
| 2.848e-04 | -8.16 | response to bacterial lipopeptide | biological process | GO:0070339 | 6 | 4 | 20694 | 1406 |
Tlr2,Cd14,Tlr1,Tlr6 |
| 2.848e-04 | -8.16 | response to mycotoxin | biological process | GO:0010046 | 6 | 4 | 20694 | 1406 |
Pdgfb,Actb,Egr1,Ass1 |
| 2.848e-04 | -8.16 | cellular response to bacterial lipoprotein | biological process | GO:0071220 | 6 | 4 | 20694 | 1406 |
Cd14,Tlr2,Tlr1,Tlr6 |
| 2.848e-04 | -8.16 | inflammasome complex | cellular component | GO:0061702 | 15 | 6 | 20747 | 1409 |
Aim2,Nlrp3,Nlrc4,Casp4,Casp1,Gsdmd |
| 2.855e-04 | -8.16 | Fc receptor signaling pathway | biological process | GO:0038093 | 15 | 6 | 20694 | 1406 |
Fcgr1,Clec4d,Fcgr2b,Nr4a3,Clec4e,Fcgr4 |
| 2.855e-04 | -8.16 | positive regulation of interleukin-6 biosynthetic process | biological process | GO:0045410 | 15 | 6 | 20694 | 1406 |
Tlr1,Il1b,Tnf,Stat3,Ptafr,Tlr6 |
| 2.855e-04 | -8.16 | cytokine biosynthetic process | biological process | GO:0042089 | 15 | 6 | 20694 | 1406 |
Gadd45g,Nod1,Irf7,Myd88,Il18,Ifnar1 |
| 2.865e-04 | -8.16 | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_FOXP3_TRASDUCED_CD4_TCELL_UP | MSigDB lists | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_FOXP3_TRASDUCED_CD4_TCELL_UP | 140 | 24 | 15632 | 1249 |
Serpine1,Plod2,Vps54,Cnp,Wars,Hmox1,Smox,Tnfsf4,Rab20,Spire1,Ier3,Il18,Cox18,Flrt3,Tcf4,Tgs1,Gpr84,Tbc1d1,Nupr1,Psme1,Sphk1,Ciapin1,Tnks1bp1,Me1 |
| 2.869e-04 | -8.16 | calcium-mediated signaling | biological process | GO:0019722 | 125 | 20 | 20694 | 1406 |
Tnf,Cacna1d,P2ry12,Irgm2,Htr2b,Ccrl2,Kdr,Edn1,Vcam1,Sphk1,Ptprj,Ccr3,Cx3cr1,Fpr2,Xcr1,Ccr1,Rcan1,Ednrb,Prnp,Slc9a1 |
| 2.875e-04 | -8.15 | GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 629 | 75 | 15632 | 1249 |
Osm,Plk2,Myadm,Jarid2,Vasn,Rapgef2,Cxcl10,Ptger4,Thbs1,Hspa1a,Gpsm2,Birc2,Rgs14,Swap70,Lrp4,Tnf,Dync1h1,Src,Hspa2,Acvrl1,Mecp2,Lztfl1,Rhoq,Kdm4a,Lif,Pml,Irak3,Lmo4,Pid1,Sema3c,Cav1,Rabgef1,Atm,Birc3,Rap1gap2,Xaf1,Sirt1,Sema4a,Mefv,Lpar1,Tmod3,Stat1,Ptk2,Sema4c,Gfi1,Pmepa1,Dnajb2,Asf1a,Cflar,Tmem67,Hmga1,Psmd10,Nlrc4,Sbds,Crbn,Ezr,Mid1,Triobp,Ifrd1,Katna1,Mmp14,Stap1,Ppp2r5a,Spry2,Bnip3,Cdk5r1,Tpx2,Nr1h3,Mul1,Pttg1,Nek6,Bcor,Evl,Chmp4b,Tspo |
| 2.878e-04 | -8.15 | GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_UP | MSigDB lists | GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_UP | 183 | 29 | 15632 | 1249 |
Psme1,Mapkapk2,Mthfr,Rhoh,Psmb10,Isg15,Fcgr1,Gbp2,Nfkbia,Ifit2,Agrn,Znfx1,Cd40,Hspa1a,Ms4a6d,Irf1,Ifit3b,Rnaset2b,Dusp16,Trafd1,Cmpk2,S100a8,Rnaset2a,Lgals9,Ifit3,Sema3c,Irf7,Nmi,Met |
| 2.878e-04 | -8.15 | GSE15767_MED_VS_SCS_MAC_LN_UP | MSigDB lists | GSE15767_MED_VS_SCS_MAC_LN_UP | 183 | 29 | 15632 | 1249 |
Lyn,Slamf8,Thbs1,Notch2,Nfxl1,Irf8,Pid1,Asah2,Slamf9,H2-Aa,Nrp2,Sell,Fpr2,F11r,Apba1,Hlx,Pdgfc,Nod1,Dock4,Homer1,Fos,Dse,Tspan3,Msr1,Lrp4,Dpy19l1,Acvrl1,Gpr35,Stard5 |
| 2.878e-04 | -8.15 | GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 183 | 29 | 15632 | 1249 |
Rnf19b,Ell2,Traf3ip2,Ripk2,Mthfd2,Igf1r,Dnajb2,Nfil3,Abcc4,Jdp2,Hopx,Casp4,Psme2,Nfkbil1,Mul1,P2ry14,Arrdc4,Traf5,Batf,1600014C10Rik,Mdfic,Dnase1l3,Axl,Spsb1,Rapgef5,Gpr18,Cyfip1,Psmb9,Abcb1a |
| 2.878e-04 | -8.15 | GSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_UP | MSigDB lists | GSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_UP | 183 | 29 | 15632 | 1249 |
Fcgr4,Il10,Flrt2,Kctd12,Ppp2r3a,Spint2,Tdrd7,Il18rap,Ripk2,Socs3,H2-Ab1,Il18,Ikbke,Prkx,Il1rn,Gfi1,Nfil3,Bcl2l11,Spn,Fgl2,Socs1,Sell,P2ry14,Il4ra,Papss2,Dcp2,Prnp,Tulp3,Sla |
| 2.878e-04 | -8.15 | GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_UP | MSigDB lists | GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_UP | 183 | 29 | 15632 | 1249 |
Rab10,Sap30,Procr,H2-Aa,Fzd1,Met,Birc3,Map4k4,Cacybp,Lgals9,Lcn2,Cep350,Ccl4,Tnfaip2,Mmp9,Rcan1,Ms4a6d,Pim1,Rsad2,Dync1h1,Jun,Cd34,Chmp4b,Tab2,Trim13,Plagl1,Il1a,Slco3a1,Jmjd6 |
| 2.880e-04 | -8.15 | GSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 157 | 26 | 15632 | 1249 |
Adrb2,Nr4a3,Rcsd1,Arl5c,Larp1,Cd55,Agpat4,Slc37a3,Vps54,Cd86,Pde4b,Egln3,Dgka,Mcoln2,Irf2,Fas,Slfn5,Cd80,Crlf3,Rapgef5,Treml2,Mafk,Phlpp1,Phgdh,Fut8,Parp14 |
| 2.880e-04 | -8.15 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_DN | 157 | 26 | 15632 | 1249 |
Prkce,Dusp4,Ifrd1,Nr4a1,Cd40,Tpst1,Itpr1,Mdfic,Rab3ip,Med13,Ksr1,Usp12,Tshz1,Pde4b,Cdyl,Cep350,Igsf8,Cd86,Cav1,Cldnd1,Clcf1,Htr2b,Gng4,St3gal1,Cdc42ep4,Il12b |
| 2.885e-04 | -8.15 | non-membrane-bounded organelle | cellular component | GO:0043228 | 4079 | 328 | 20747 | 1409 |
Ppp2r5a,Cdkn1a,Clmp,Pik3r5,Fnbp1l,Rmdn3,Atf3,Kif5c,Etv3,Psip1,Homer1,Hdac1,Nr1h3,Tyk2,Mcm9,Ubr4,Crbn,Stau1,Zc3h12a,Gypc,Acsl5,Trip13,Pdk3,Tulp3,Ift22,Phf6,Tpx2,Smg7,Cutc,Map2k1,Myo10,Nr3c1,Fcgr2b,Nfkbiz,Lad1,Gpsm2,Sco1,Mndal,Sgcb,Myc,Atp6v1d,Ddx60,Intu,Klf6,Mapkapk2,Ifi207,Sp140,Ciapin1,Taf4b,Cited2,Itpr1,Rai14,Rap1gap2,Eef1e1,Mov10,Igf2bp2,Tnks1bp1,Arid5a,Tra2a,Larp1,Ddx4,Cenpj,Samhd1,Cep350,Nes,Pcgf5,Hap1,Nsd3,Sbds,Cnn2,Mecp2,Ppp4r2,Ifi209,Irf4,Ift57,Flnb,Snx10,Zyx,Parp3,Dst,Rab3ip,Plk3,Ccdc88b,Sirt1,Syne2,Dnaja1,Ccdc86,Junb,Fam111a,Cdyl,Klf2,Clic4,Noc4l,Irf1,Tmod3,Jun,Ifi214,Dync1i2,Mdn1,Ankrd17,Cdk5r1,Spry2,Phlda1,Frmd4a,Sele,Trib3,Cnp,Wdr43,Rbl1,Dcp2,Grk3,Resf1,Pml,Rcl1,Kif9,Mvp,Swap70,Atp2b4,Daam1,Rrs1,Abr,Atm,Radx,Tma16,Rnd1,Kmt5a,Prdx1,Mtus1,Myadm,Hspa2,Hsph1,Marcksl1,Top3a,Rnf19a,Mefv,Rgcc,Ifi204,Trim12c,Asf1a,Prkce,Sap30,Ikbkg,Jak2,Hmgn3,Txnrd1,Dync1h1,Dyrk2,Jmjd6,Prkar2b,Gng12,Snapc1,Tcf4,Dcp1a,Myo1b,Pde4b,Ctsc,Ikzf1,Xrn1,Fcho2,Mark2,Keap1,Noct,G3bp2,Src,Nfkbie,Nek6,Procr,Mmp14,Frmd6,Sdc4,Lyn,Daxx,Pim1,Nlrc5,N4bp1,Rhoq,Hmox1,Adar,Hck,Cdc42ep4,Rgs14,Timeless,Stat1,Rhof,Fscn1,Pla2g4a,Lipe,Rbpms,Traf5,Tap1,Pstpip2,Tdrd7,Uaca,Mdm2,Vasp,Evl,Tpm4,Tent4a,Lrp8,Sipa1l1,Rilpl1,Mcm10,Riox2,Gem,Kif3c,Ripk2,Triobp,Flt1,Slc16a1,Katna1,Mid1,Micall2,Smc5,Hat1,Vcam1,Birc2,Arl4a,Trip10,Nos2,Bcl6,Sod2,Max,Socs1,Srgn,Serp1,Ehd1,Ifi213,Slc2a1,Arhgap26,Isg20,Cacna1d,Prdm9,Rabgef1,Tuba4a,Golga3,Dbnl,Carmil1,Marcks,Rac3,Icosl,Whamm,Bcl2l11,Psmd10,Malt1,Ptk2,Polr2g,Fgr,Ncoa5,Mtdh,Rpgrip1l,Slc7a11,Spire1,Setdb2,Plscr1,Stxbp1,Cdc42ep2,Carhsp1,Actb,Mdfic,Mrpl52,S100a8,Parp10,Sinhcaf,Kdm4a,Ifi211,Psd,Clic5,Tlk2,Mapkbp1,Ccne1,Tmem67,Mxd1,Zfp36,Ifi208,Hmga2,Ddx58,Parp9,Gbp2,Pnpt1,Tcea1,H3f3b,Ifi203,Pdlim7,Cgas,Gja1,Sqstm1,Cnn3,Trim36,Rbbp8,Ppp1r12b,Psma6,Ago3,Csrp1,Ep400,Kat2b,Cav1,Rsad2,Cep85l,Nod2,Dock4,Plekhn1,Sass6,Sertad3,Ccnd2,Relb,Rims3,Kitl,Ifi205,Stat3,Etv6,Hspa1a,Pkp4,Oasl1,Nck1,Hilpda,Cenpe,Palld,Plk2,Mcmbp,Adora2a,Hcls1,Ezr,Lpcat2,Dennd2a,Eif2ak2,Hif1a,Dek,Hmga1 |
| 2.919e-04 | -8.14 | mouse chr1 | chromosome location | mouse chr1 | 395 | 42 | 24173 | 1464 |
Btg2,Dst,Sele,Ptgs2os2,Rrs1,Traf5,Stat1,Gsta3,Hlx,Atp2b4,Serpinb2,Fcgr4,Ifi203,Casp8,Igsf9,Inpp1,Mndal,Atf3,Igsf8,Cd34,Cd55,Sell,Ifi205,Tnfsf4,Cflar,Rgs1,Fcgr2b,D1Ertd622e,Sp100,Mcm6,Fzd5,Ifi204,Ptgs2,F11r,Stat4,Sgk3,Pla2g4a,Myo1b,Slc30a1,Pbx1,Il10,Kdm5b |
| 2.930e-04 | -8.14 | GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_UP | MSigDB lists | GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_UP | 192 | 30 | 15632 | 1249 |
Csf3,Psme2,Casp8,Jdp2,Birc3,Acsl5,Fscn1,Sema4a,Rcn1,Adora2b,Sema4c,Tapbp,Arhgap26,Dbnl,Dusp2,Rai14,Ctsc,Gpr18,Cst7,Aoah,Spn,Tnfaip3,Olfml3,Tle3,Lpcat2,Rnd1,Nmral1,Spata13,Lif,Psme1 |
| 2.931e-04 | -8.13 | AAGCCAT_MIR135A_MIR135B | MSigDB lists | AAGCCAT_MIR135A_MIR135B | 302 | 42 | 15632 | 1249 |
Slc39a13,Hif1a,Ccnd2,Atf3,Chmp4b,Atp2b4,Extl2,Mapkbp1,Mtus1,Psip1,Zswim4,Aebp2,Ccng2,Cpd,Slc44a1,Peli1,Acvr1b,Usp42,Fcho2,Arid5b,Gpr85,Frmd4a,Mtdh,Herc6,Dgkh,Ptk2,Kpna3,Pim2,Dusp5,Igf2bp2,Jak2,Cacna1d,Rgl1,Mier3,Jdp2,Inhba,Sirt1,Stx6,Pde7b,Kctd12,Akt3,Phlpp2 |
| 2.931e-04 | -8.13 | GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | MSigDB lists | GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | 302 | 42 | 15632 | 1249 |
Apba1,Lif,Hhex,Prdm1,Slc30a1,Hif1a,Bmp2,Adar,Hinfp,Angpt1,Notch1,Plod3,Sbds,Bcl2l11,Rbbp8,Mgat1,Eno1,Spic,Edn1,Fut8,Acvrl1,Acvr1,Socs3,Mafg,Rcn1,Acvr1b,Rpgrip1l,Keap1,Gja1,Junb,Ptch1,Map2k1,Casp8,Med21,P2ry2,Il10,Klf2,Hopx,Fzd5,Pdgfb,Inpp5b,Maff |
| 2.940e-04 | -8.13 | FALVELLA_SMOKERS_WITH_LUNG_CANCER | MSigDB lists | FALVELLA_SMOKERS_WITH_LUNG_CANCER | 69 | 15 | 15632 | 1249 |
Mapkapk2,Pgs1,Nr4a3,Rcan1,Serpinb2,Sod2,Ahrr,Ezr,Dusp1,Nampt,Serpine1,Btg2,Micall2,Met,B3gnt5 |
| 2.944e-04 | -8.13 | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN | MSigDB lists | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN | 35 | 10 | 15632 | 1249 |
Gpc1,Sdc2,Vcan,Ltbp2,Syk,Lpar1,Timp1,Sdc1,Sema3c,Lox |
| 2.953e-04 | -8.13 | phagocytic vesicle | cellular component | GO:0045335 | 89 | 16 | 20747 | 1409 |
Tlr9,Stxbp3,Evl,Irgm1,Rab20,Rab32,Tlr1,Cdc42ep4,Zyx,Syk,Cdc42ep2,Rab9,Stx11,Stxbp1,Stx6,Flnb |
| 2.956e-04 | -8.13 | GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION | 558 | 68 | 15632 | 1249 |
Bmp2,Pbx1,Notch1,Daxx,Hlx,Cd74,Stat3,Gpr68,Acvrl1,Mecp2,Ccnd1,Hdac1,Lrp4,Tnf,Ankrd17,Bcl6,P2ry12,Il1b,Pf4,Zhx2,Tlr3,Cxcl10,Il18,Trib3,Pdgfb,Nfkbid,Vasn,Inhba,Rapgef2,Hopx,Plk2,Tspo,Tmem176b,Cdk5r1,Il4ra,Nr1h3,Ubash3b,Katna1,Stap1,Il6,Myc,Ifnb1,Cxcl14,Ifrd1,Itgav,Nfkbia,Ptpn2,Cflar,Gfi1,Stat1,Ptk2,Tnfsf4,Sema4c,Sema4a,Lyn,Trib1,Irf1,Lpar1,Zeb1,Rap1gap2,Tmem176a,Sirt1,Jag1,Jdp2,Ednrb,Ptch1,Sema3c,Cav1 |
| 2.962e-04 | -8.12 | GO_G_PROTEIN_COUPLED_PURINERGIC_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_G_PROTEIN_COUPLED_PURINERGIC_RECEPTOR_SIGNALING_PATHWAY | 18 | 7 | 15632 | 1249 |
Adora2b,P2ry12,Ptafr,P2ry13,P2ry2,P2ry14,Adora2a |
| 2.962e-04 | -8.12 | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP | MSigDB lists | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP | 18 | 7 | 15632 | 1249 |
Pim1,F11r,Pdgfb,Tnc,Edn1,Cd200,Thbs1 |
| 2.962e-04 | -8.12 | GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | 18 | 7 | 15632 | 1249 |
Ifnb1,Irak3,Angpt1,Il10,Bcl6,Tnf,Hmox1 |
| 2.962e-04 | -8.12 | GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | 18 | 7 | 15632 | 1249 |
Stap1,Syk,C3,Adora2b,Fgr,Il4ra,Ptafr |
| 2.962e-04 | -8.12 | AMIT_DELAYED_EARLY_GENES | MSigDB lists | AMIT_DELAYED_EARLY_GENES | 18 | 7 | 15632 | 1249 |
Zfp36,Rbms1,Btg2,Maff,Atf3,Junb,Klf6 |
| 2.962e-04 | -8.12 | NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_DN | MSigDB lists | NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_DN | 18 | 7 | 15632 | 1249 |
Ampd3,Plat,Tnfsf10,Fgl2,Rbpms,Nupr1,Casp1 |
| 2.963e-04 | -8.12 | TIEN_INTESTINE_PROBIOTICS_24HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_24HR_DN | 201 | 31 | 15632 | 1249 |
Atf3,Prnp,Sat1,Gclm,Aftph,Ifrd1,Nqo1,Hsph1,Txnrd1,Sqstm1,Tank,Serp1,Arf4,Gfpt1,Glrx,Tcea1,Nfil3,Rnf19b,Cd55,Mtdh,Fndc3a,Trib3,Mthfd2,Ddit4,Phlda1,Wars,Jag1,Vasp,Gdf15,Asns,Ppp1r15a |
| 2.966e-04 | -8.12 | GO_REGULATION_OF_COAGULATION | MSigDB lists | GO_REGULATION_OF_COAGULATION | 84 | 17 | 15632 | 1249 |
Adrb2,Lyn,Ubash3b,Plaur,Enpp4,Thbs1,Serpinb2,Plat,Cd34,Plau,Serpine1,Cav1,Syk,Plek,Procr,Pdgfb,Edn1 |
| 2.973e-04 | -8.12 | IG_MHC | prosite domains | PS00290 | 56 | 13 | 13278 | 1037 |
H2-T10,H2-Q7,H2-M2,Tapbpl,H2-Aa,H2-T22,Tapbp,H2-Q6,Siglece,H2-T24,H2-Q4,H2-Ab1,H2-Eb1 |
| 2.973e-04 | -8.12 | PID_S1P_S1P3_PATHWAY | MSigDB lists | PID_S1P_S1P3_PATHWAY | 29 | 9 | 15632 | 1249 |
Itgav,Src,Flt1,Pdgfrb,Gna15,Akt3,Jak2,Pdgfb,S1pr2 |
| 2.973e-04 | -8.12 | GO_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS | 29 | 9 | 15632 | 1249 |
Vcam1,Nrp2,Kdr,Notch1,Flt1,Egr3,Nr4a1,Mapkapk2,Pdgfrb |
| 2.973e-04 | -8.12 | GO_CCR_CHEMOKINE_RECEPTOR_BINDING | MSigDB lists | GO_CCR_CHEMOKINE_RECEPTOR_BINDING | 29 | 9 | 15632 | 1249 |
Cx3cl1,Ccl22,Ccl5,Ccl12,Ccl3,Ccrl2,Ccl4,Ccl2,Stat3 |
| 2.973e-04 | -8.12 | NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_UP | MSigDB lists | NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_UP | 29 | 9 | 15632 | 1249 |
Myc,Stat3,Cdk5r1,Ccnd2,Nfkb1,Ccne1,Nfkbia,Gadd45b,Casp7 |
| 2.973e-04 | -8.12 | GO_GLUCOSE_CATABOLIC_PROCESS | MSigDB lists | GO_GLUCOSE_CATABOLIC_PROCESS | 29 | 9 | 15632 | 1249 |
Hk2,Pgk1,Pfkl,Hk3,Pfkfb3,Eno1,Tpi1,Hk1,Eno2 |
| 2.973e-04 | -8.12 | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | MSigDB lists | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | 29 | 9 | 15632 | 1249 |
Tnfrsf1b,Pim1,Upp1,Irf1,Fgr,Ier3,Tnfaip2,Sla,Cd38 |
| 2.981e-04 | -8.12 | MEL18_DN.V1_DN | MSigDB lists | MEL18_DN.V1_DN | 132 | 23 | 15632 | 1249 |
Phyh,Oas1g,Dio2,Pid1,Plekha4,Ifit1bl2,Pde4b,Oas1a,Eya4,Tmem176a,Pde7b,Ube2l6,Slpi,Ddx60,Tmem176b,Egr1,Mvp,Fos,Ifit2,Ifit1bl1,Pde5a,Cxcl14,Dusp2 |
| 2.986e-04 | -8.12 | regulation of leukocyte degranulation | biological process | GO:0043300 | 48 | 11 | 20694 | 1406 |
Ptafr,Stxbp1,Syk,Fgr,Hmox1,Rabgef1,Il4ra,Abr,Lgals9,Lyn,Adora2b |
| 2.990e-04 | -8.12 | GO_RESPONSE_TO_GAMMA_RADIATION | MSigDB lists | GO_RESPONSE_TO_GAMMA_RADIATION | 48 | 12 | 15632 | 1249 |
Tlk2,Myc,Cav1,Atm,Ccl12,Dcun1d3,Il1b,Trim13,Cxcl10,Egr1,Socs3,Pml |
| 2.990e-04 | -8.12 | ZHOU_TNF_SIGNALING_4HR | MSigDB lists | ZHOU_TNF_SIGNALING_4HR | 48 | 12 | 15632 | 1249 |
Tnfaip2,Clic4,Tnip1,Prdx1,Ptges,Ccl12,Sod2,Tuba4a,Nfkb1,Nfkbia,Psmb8,Tspan3 |
| 2.998e-04 | -8.11 | P53_DN.V1_UP | MSigDB lists | P53_DN.V1_UP | 166 | 27 | 15632 | 1249 |
Spry2,Birc2,Gpsm2,Axl,Ass1,Enpp4,Mark2,Crim1,Ahr,Rras2,Sdc4,Plau,Arl4a,Cdkn2d,Maff,Vasp,Spint2,Cnn3,Sap30,Daam1,Tuba4a,Inpp1,Irf1,Adora2b,Tgfbi,Il18,Uchl1 |
| 2.998e-04 | -8.11 | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_UP | MSigDB lists | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_UP | 166 | 27 | 15632 | 1249 |
Rhou,Mmd,Phlda1,Tnfsf14,Plekhg1,Samsn1,Hopx,Ccl5,Plek,Clic5,Gfi1,Adrb2,Gpr68,Ogfrl1,Lztfl1,Dusp8,Ctsc,Abcb1a,Timp1,Cyfip1,Dse,Plod3,Ahr,Atp2b4,Prnp,Kat2b,Zfp513 |
| 2.998e-04 | -8.11 | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_DN | 166 | 27 | 15632 | 1249 |
Plac8,Trmt1l,Phldb1,Srm,Swap70,Myc,Pde1b,Ogfrl1,Cept1,Acvr1,Ddx58,Klf7,Zc3hav1,Osm,Zeb1,Ep400,Rtn2,Atxn7l1,Pou2f2,Max,Atp10a,Hmox1,Arid5b,Ier3,Serpinb2,Stard7,Tfec |
| 3.015e-04 | -8.11 | positive regulation of mitochondrion organization | biological process | GO:0010822 | 72 | 14 | 20694 | 1406 |
Kdr,Hif1a,Hk2,Fas,Mul1,Fam162a,Tnfsf10,Mmp9,Bcl2l11,Bnip3,Optn,Plaur,Ddhd1,Pmaip1 |
| 3.023e-04 | -8.10 | regulation of fibroblast proliferation | biological process | GO:0048145 | 107 | 18 | 20694 | 1406 |
Jun,Sod2,Serpine1,Nupr1,Pdgfb,Sphk1,Cd74,Pmaip1,Pml,Cdkn1a,Morc3,Dach1,Parp10,Myc,Fbxo4,Mmp9,Pdgfrb,Pdgfc |
| 3.031e-04 | -8.10 | negative regulation of cell growth | biological process | GO:0030308 | 194 | 27 | 20694 | 1406 |
Sema4a,Pml,Cdkn1a,Sertad3,Ptprj,Dcbld2,Sema3c,Gng4,Acvrl1,Mul1,Dcun1d3,Mecp2,Sh3bp4,Acvr1b,Mndal,Bcl6,Tomm70a,Sirt1,Cdkn2d,Dnajb2,Crlf3,Osgin2,Inhba,Cdk5r1,Ifrd1,Sema4c,Gja1 |
| 3.036e-04 | -8.10 | RNA polymerase II-specific DNA-binding transcription factor binding | molecular function | GO:0061629 | 283 | 36 | 20217 | 1400 |
Psma6,Stat3,Ets2,Rbl1,Fos,Taf4b,Jun,Actb,Rnf14,Nr4a3,Src,Mier3,Stat1,Nfkbia,Daxx,Sirt1,Notch2,Nr1h3,Nr4a1,Ahr,Hif1a,Ncoa7,Cited2,Egr2,Arid5a,Dnaja1,Hmga1,Mtdh,Mdfic,Nfkbid,Ifrd1,Crkl,Med13,Rbbp8,Hdac1,Hspa1a |
| 3.043e-04 | -8.10 | GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_DN | 149 | 25 | 15632 | 1249 |
Olr1,Sdc4,Mafg,Rab20,Ak4,Tpi1,Hmox1,Tnfsf4,Atf3,Dtnb,Gpr68,Csf3,Mdm2,Mecp2,Rbpms,Phlda1,Bnip3,Eno1,P2ry2,Slc2a1,Osm,Gna15,Slc16a3,P4ha1,Eno2 |
| 3.047e-04 | -8.10 | GO_ANCHORING_JUNCTION | MSigDB lists | GO_ANCHORING_JUNCTION | 458 | 58 | 15632 | 1249 |
Mmp14,Triobp,Itgav,Flrt3,Cnn2,Ezr,Flt1,Zyx,Hmga1,Cyfip1,Rras2,Sdc4,Plau,Rnd3,Ppfibp1,Palld,Evl,Mpp7,Sdc1,Flnb,Slc9a1,Cnn3,Procr,Rhou,Syne2,Jag1,Lap3,Layn,Cav1,Vezt,Actb,Itga5,Cd200,Ptk2,Lyn,Tnc,Rab21,Arhgap26,Hspa1a,Hck,Notch1,Asap3,Itga4,Irf2,Rnd1,Icam1,Pdlim7,Rab10,Fzd1,Vasp,Gja1,Csrp1,Map2k1,Pdgfrb,Flrt2,Keap1,Plaur,Pkp4 |
| 3.058e-04 | -8.09 | PID_IL4_2PATHWAY | MSigDB lists | PID_IL4_2PATHWAY | 62 | 14 | 15632 | 1249 |
Jak2,Socs1,Il4ra,Il2rg,Irs2,Il13ra1,Socs3,Egr2,Irf4,Parp14,Hmga1,Bcl6,Il10,Stat5a |
| 3.058e-04 | -8.09 | GENTILE_UV_LOW_DOSE_DN | MSigDB lists | GENTILE_UV_LOW_DOSE_DN | 62 | 14 | 15632 | 1249 |
Gbe1,Rbms1,Myo10,Angpt1,Vegfc,Igf1r,Sipa1l1,Tpst1,Sema3c,Ext1,Ddit4,Ppp2r3a,Met,Ap3b1 |
| 3.059e-04 | -8.09 | BBOX | smart domains | SM00336 | 58 | 14 | 9567 | 823 |
Trim13,Trim34a,Mefv,Pml,Trim30a,Trim14,Mid1,Trim12a,Trim56,Trim12c,Trim26,Trim30d,Trim36,Trim21 |
| 3.067e-04 | -8.09 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway | molecular function | GO:0097199 | 6 | 4 | 20217 | 1400 |
Casp4,Casp1,Casp3,Casp8 |
| 3.067e-04 | -8.09 | podosome | cellular component | GO:0002102 | 27 | 8 | 20747 | 1409 |
Fscn1,Kif9,Dbnl,Tpm4,Actb,Src,Palld,Vcam1 |
| 3.076e-04 | -8.09 | modification by symbiont of host morphology or physiology | biological process | GO:0044003 | 27 | 8 | 20694 | 1406 |
Tnip1,Irgm2,Serpinb9,Tlr2,Myc,Irgm1,Mmp9,Bcl2l11 |
| 3.076e-04 | -8.09 | regulation of nuclease activity | biological process | GO:0032069 | 27 | 8 | 20694 | 1406 |
Oas2,Oas3,Sirt1,Oas1a,Oasl2,Oas1g,Oasl1,Oas1b |
| 3.088e-04 | -8.08 | PID_TXA2PATHWAY | MSigDB lists | PID_TXA2PATHWAY | 55 | 13 | 15632 | 1249 |
Icam1,Lyn,Fgr,Ptgir,Hck,Vcam1,Gna15,Pik3r6,Src,Pik3r5,Syk,Sele,Prkce |
| 3.092e-04 | -8.08 | GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_DN | MSigDB lists | GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_DN | 175 | 28 | 15632 | 1249 |
Itga9,Ppfibp2,Gcnt2,Ikbke,Clcn7,P2ry2,Serpine1,Osm,Irf7,Rgl1,Fcgr4,Stx11,Jag1,Icosl,Isg15,Cyth3,Kmo,Etv3,Slc30a4,Angpt1,Me1,Mapkbp1,F10,Itgav,Dtnb,Itgb8,Rnf24,Prkce |
| 3.092e-04 | -8.08 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 175 | 28 | 15632 | 1249 |
Tnfaip2,Fscn1,Il18,Ptafr,Irf1,Ptgir,Dtx2,Parp3,Uba7,Bst1,Scn1b,Tlr1,Inpp5b,Irf7,Tnfsf14,Ccl5,Gdf15,Rgl1,Tap1,Etv5,Tnfrsf14,Nfkbie,Fchsd2,Tmem184b,Cyfip1,Ehd1,Tnf,Aoah |
| 3.092e-04 | -8.08 | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 175 | 28 | 15632 | 1249 |
Irf4,Lrch1,Slc15a3,Rai14,Phlpp1,Hivep2,Acpp,Trp53i11,Rras2,Sdc4,Slamf7,Pde3b,Rab3ip,Klf7,Cd38,Relb,Tnfaip3,Gbp2,Cdkn2d,Hivep3,Tnfsf10,Adam19,Snn,Dck,Dyrk2,Uaca,Parp3,Spata5l1 |
| 3.092e-04 | -8.08 | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN | 175 | 28 | 15632 | 1249 |
Rnf31,Pde4b,Hopx,Tlr1,Stxbp3,Trim14,Tyk2,Atp10a,Rnf19b,Slfn9,Znrf1,Ppp2r2a,Slc37a3,Slfn8,Hspa2,Dhx58,Rhoh,Irf2,Rars,Nfkbiz,Nfkbil1,Arrdc4,Rtp4,Psmb10,Cdc42ep2,Extl2,Zfp319,Mcmbp |
| 3.092e-04 | -8.08 | GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_UP | MSigDB lists | GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_UP | 175 | 28 | 15632 | 1249 |
Icam1,Plk3,Plagl2,Tnfaip3,Tle3,Sdc4,Arhgef3,Bcl6,Taf4b,Nr3c1,Myc,Odc1,Rcan1,Adora2b,Mthfd2,H3f3b,Osbpl3,Slc29a3,Clic4,Irf8,Rel,Birc3,Ednrb,Hivep3,Hk2,Bcl9,Zeb1,Btg2 |
| 3.097e-04 | -8.08 | GO_MAINTENANCE_OF_LOCATION_IN_CELL | MSigDB lists | GO_MAINTENANCE_OF_LOCATION_IN_CELL | 92 | 18 | 15632 | 1249 |
Gpsm2,Il10,Psmd10,Cav1,Hk1,Nfkbia,Ezr,Morc3,Syne2,Hk2,Nfkbie,G3bp2,Nfkbib,Flnb,Pml,Nfkbil1,Keap1,Tspo |
| 3.098e-04 | -8.08 | ST_TYPE_I_INTERFERON_PATHWAY | MSigDB lists | ST_TYPE_I_INTERFERON_PATHWAY | 9 | 5 | 15632 | 1249 |
Ifnb1,Tyk2,Stat2,Ifnar1,Stat1 |
| 3.098e-04 | -8.08 | BIOCARTA_BLYMPHOCYTE_PATHWAY | MSigDB lists | BIOCARTA_BLYMPHOCYTE_PATHWAY | 9 | 5 | 15632 | 1249 |
Icam1,Itgal,Cd40,Fcgr2b,Cd80 |
| 3.098e-04 | -8.08 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | MSigDB lists | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | 9 | 5 | 15632 | 1249 |
Kdr,Nrp2,Flt1,Vegfc,Pdgfc |
| 3.098e-04 | -8.08 | CHEN_HOXA5_TARGETS_6HR_UP | MSigDB lists | CHEN_HOXA5_TARGETS_6HR_UP | 9 | 5 | 15632 | 1249 |
Egr1,Ier2,Gadd45b,Sat1,Tiparp |
| 3.130e-04 | -8.07 | detection of bacterial lipopeptide | biological process | GO:0070340 | 3 | 3 | 20694 | 1406 |
Tlr2,Tlr1,Tlr6 |
| 3.130e-04 | -8.07 | positive regulation of MDA-5 signaling pathway | biological process | GO:1900245 | 3 | 3 | 20694 | 1406 |
Dhx58,Ankrd17,Ddx60 |
| 3.130e-04 | -8.07 | response to triacyl bacterial lipopeptide | biological process | GO:0071725 | 3 | 3 | 20694 | 1406 |
Tlr2,Cd14,Tlr1 |
| 3.130e-04 | -8.07 | regulation of interleukin-4-mediated signaling pathway | biological process | GO:1902214 | 3 | 3 | 20694 | 1406 |
Cd300lf,Parp14,Ptpn2 |
| 3.130e-04 | -8.07 | regulation of macrophage colony-stimulating factor signaling pathway | biological process | GO:1902226 | 3 | 3 | 20694 | 1406 |
Csf1,Ptpn2,Stap1 |
| 3.130e-04 | -8.07 | glomerular mesangial cell proliferation | biological process | GO:0072110 | 3 | 3 | 20694 | 1406 |
Pdgfb,Pdgfrb,Egr1 |
| 3.130e-04 | -8.07 | cellular response to triacyl bacterial lipopeptide | biological process | GO:0071727 | 3 | 3 | 20694 | 1406 |
Tlr2,Cd14,Tlr1 |
| 3.130e-04 | -8.07 | regulation of miRNA catabolic process | biological process | GO:2000625 | 3 | 3 | 20694 | 1406 |
Tent2,Zc3h12a,Pnpt1 |
| 3.141e-04 | -8.07 | negative regulation of lymphocyte differentiation | biological process | GO:0045620 | 56 | 12 | 20694 | 1406 |
Socs1,Nfkbid,Ifnb1,Il4ra,Hlx,Fgl2,Irf1,Ptpn2,Zc3h12a,Bcl6,Tnfsf4,Cd74 |
| 3.161e-04 | -8.06 | - | gene3d domains | 3.30.505.10 | 109 | 21 | 8819 | 755 |
Crkl,Socs7,Jak2,Rin2,Stap1,Src,Stat5a,Nck1,Syk,Stat2,Lyn,Fgr,Socs3,Stat4,Sla,Stat3,Hck,Socs1,Cish,Stat1,Lcp2 |
| 3.162e-04 | -8.06 | GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_UP | 184 | 29 | 15632 | 1249 |
Mitd1,Tnip1,Slfn9,Znrf1,Sp110,Ap3m2,Dyrk2,Dnaja2,Rcsd1,Kcna3,Adora2a,Trim56,Lnpep,Casp8,Lcp2,Rbm43,Gbp2,Daxx,Ddx60,Nck1,Rtp4,Ppp2r5a,Peli1,Phgdh,Slfn8,Ikzf1,Mllt6,Ifit2,Ezr |
| 3.162e-04 | -8.06 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_INF_DN | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_INF_DN | 184 | 29 | 15632 | 1249 |
Mmd,Rnf19a,Egln3,Ext1,Asah2,Atp6v1d,Pde4b,Igf1r,Tagap,Snn,Trib3,Cdc42ep4,Nr4a3,Rab20,Egr3,Cd200,Cers6,Ift57,Egr2,Aftph,Tspan3,Cst7,Rab3ip,Spred1,Traf5,Ubash3b,Prnp,Cyth3,Hif1a |
| 3.188e-04 | -8.05 | protein tyrosine kinase activity | molecular function | GO:0004713 | 133 | 21 | 20217 | 1400 |
Flt1,Sla,Src,Hck,Eif2ak2,Dyrk2,Ptk2,Pdgfrb,Ripk2,Syk,Igf1r,Jak2,Kdr,Nrp2,Tyk2,Map2k4,Map2k1,Lyn,Met,Axl,Fgr |
| 3.188e-04 | -8.05 | aromatic compound catabolic process | biological process | GO:0019439 | 289 | 36 | 20694 | 1406 |
Apobec3,Tent4a,Atm,Upp1,Hdc,Pnpt1,Mgat1,Magohb,Noct,Slfn8,Dcp2,Gtpbp2,Tut7,Rnaset2a,Ago3,Samhd1,Smg7,Cnp,Isg20,Dio2,Xrn1,Helz2,Tent2,Hmox1,Zhx2,Zfp36,Zc3h12a,Dcp1a,Dnase1l3,Oas2,Pde5a,Enpp4,Kmo,Gda,Polr2g,Tet2 |
| 3.189e-04 | -8.05 | KRAS.600_UP.V1_UP | MSigDB lists | KRAS.600_UP.V1_UP | 238 | 35 | 15632 | 1249 |
Etv5,Plau,Gng11,Cd80,St3gal6,Cdk5r1,Fabp3,Dusp4,Spry2,Lrch1,Gpr18,Dock4,Trim36,Dhrs9,Fmnl2,Vegfc,Dcbld2,Glrx,Gfi1,Cmklr1,Adam19,Plat,Ptgs2,Nr4a3,Mmp9,Rtn1,Kif5c,Inhba,Csf3,Mmd,Cxcl2,Zeb1,Tnfsf15,Scn1b,Dusp6 |
| 3.210e-04 | -8.04 | GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_UP | 193 | 30 | 15632 | 1249 |
Notch2,Dek,Nfkb2,Gca,Sema4c,Casp7,Kpna3,Il13ra1,Rcan1,Mob3b,Serpinb9,Map2k4,Tlr2,Tor3a,Snx10,Zc3h12c,Lap3,Hk3,Cd38,Magohb,Mapkapk2,Palld,Rnf135,D1Ertd622e,Il4i1,Arhgap26,Cenpe,B4galt4,Itpr1,Hmga1 |
| 3.210e-04 | -8.04 | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 193 | 30 | 15632 | 1249 |
Src,Gadd45b,Parp8,Arid5a,Bcl6,Eno1,Dusp2,Icam1,Cd34,Bfar,1600014C10Rik,Ccr1,Itgal,Trim14,Alas1,Smpdl3b,Stat4,Met,Egln3,Etv6,Ebi3,Socs3,Acvr1b,Rcsd1,Nr4a3,Tapbpl,Vegfc,Trem1,Pgk1,Tfec |
| 3.233e-04 | -8.04 | CCAWWNAAGG_SRF_Q4 | MSigDB lists | CCAWWNAAGG_SRF_Q4 | 77 | 16 | 15632 | 1249 |
Klf6,Nr4a1,Csrp1,Tagln,Tcf4,Fosb,Ptch1,Egr2,Dusp2,Prdm1,Egr1,Mapkapk2,Dusp5,Pcdh7,Actb,Thbs1 |
| 3.233e-04 | -8.04 | GO_ACUTE_INFLAMMATORY_RESPONSE | MSigDB lists | GO_ACUTE_INFLAMMATORY_RESPONSE | 77 | 16 | 15632 | 1249 |
Hp,Tnfsf4,Nupr1,Il1a,Hif1a,Icam1,Vcam1,Il1rn,Il1b,Ptges,S100a8,Ass1,Stat3,Il6,Plscr1,Acvr1 |
| 3.233e-04 | -8.04 | MODULE_107 | MSigDB lists | MODULE_107 | 77 | 16 | 15632 | 1249 |
Olr1,F10,Plau,Plat,Hp,Mmp9,Mmp13,C1ra,Ctsc,Mmp14,Htra1,Psmb9,Timp1,Lap3,Casp4,Casp1 |
| 3.252e-04 | -8.03 | positive regulation of actin filament polymerization | biological process | GO:0030838 | 81 | 15 | 20694 | 1406 |
Vasp,Carmil1,Fchsd2,Rictor,Icam1,Prkce,Spire1,Cyfip1,Rac3,Nck1,Evl,Whamm,Csf3,Cdc42ep4,Cdc42ep2 |
| 3.252e-04 | -8.03 | regulation of coagulation | biological process | GO:0050818 | 81 | 15 | 20694 | 1406 |
Ubash3b,Pdgfb,Syk,Pdpn,Lyn,Cav1,Serpine1,Procr,Plek,Plau,Thbs1,Adrb2,Cd34,Ptprj,Enpp4 |
| 3.258e-04 | -8.03 | regulation of neutrophil migration | biological process | GO:1902622 | 41 | 10 | 20694 | 1406 |
Nod2,Cd74,Sell,Il1a,Il1b,Ptger4,Slamf8,Bst1,Myd88,Edn1 |
| 3.258e-04 | -8.03 | antigen processing and presentation of endogenous antigen | biological process | GO:0019883 | 41 | 10 | 20694 | 1406 |
H2-T22,H2-Q6,H2-Q7,H2-Q4,Tap2,Tap1,Tapbp,H2-T24,H2-T10,H2-M2 |
| 3.258e-04 | -8.03 | protein kinase B signaling | biological process | GO:0043491 | 41 | 10 | 20694 | 1406 |
Kdr,Cd40,Ccl5,Plk3,Ccl12,Il1b,Tnf,Lox,P2ry12,Axl |
| 3.258e-04 | -8.03 | viral entry into host cell | biological process | GO:0046718 | 41 | 10 | 20694 | 1406 |
Clec5a,Nectin4,Itgav,Cd300lf,Nectin2,Cd55,Axl,Pvr,Tnfrsf14,Cav1 |
| 3.281e-04 | -8.02 | positive regulation of macrophage chemotaxis | biological process | GO:0010759 | 21 | 7 | 20694 | 1406 |
Ccl2,Cmklr1,Thbs1,Csf1,Cx3cl1,Ccl5,Ptprj |
| 3.310e-04 | -8.01 | GSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_DN | MSigDB lists | GSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_DN | 167 | 27 | 15632 | 1249 |
Tnf,Psmb9,Irf4,Tapbp,Psma6,Fgl2,Psme1,Ier2,Aim2,Nxf1,Sell,Psmb10,Gclc,Fcgr1,Rbms2,Me1,S100a8,Rrs1,Psme2,Rap1gap2,Uba7,Bst1,Wars,H2-Ab1,Larp1,Il2rg,Plat |
| 3.314e-04 | -8.01 | TAP1 binding | molecular function | GO:0046978 | 3 | 3 | 20217 | 1400 |
Tap1,Tapbp,Tap2 |
| 3.314e-04 | -8.01 | TAP2 binding | molecular function | GO:0046979 | 3 | 3 | 20217 | 1400 |
Tap2,Tapbp,Tap1 |
| 3.314e-04 | -8.01 | ISG15 transferase activity | molecular function | GO:0042296 | 3 | 3 | 20217 | 1400 |
Ube2e1,Ube2e2,Ube2l6 |
| 3.329e-04 | -8.01 | cellular response to peptide hormone stimulus | biological process | GO:0071375 | 185 | 26 | 20694 | 1406 |
Pde3b,Cyfip1,Stat5a,Slc9a1,Irf1,Stat3,Src,Agtrap,Nr4a1,Igf1r,Socs7,Rhoq,Phip,Stat1,Jak2,Kat2b,Irs2,Nfkb1,Cav1,Nr4a3,Rab10,Il18,Ptpn2,Ptk2,Trib3,Akt3 |
| 3.331e-04 | -8.01 | cytokine receptor activity | molecular function | GO:0004896 | 97 | 17 | 20217 | 1400 |
Il4ra,Gpr35,Ccr3,Il15ra,Il12rb1,Ifnar1,Il18rap,Ebi3,Il12b,Ccr1,Ccrl2,Xcr1,Il13ra1,Il2rg,Csf3r,Cx3cr1,Cd74 |
| 3.331e-04 | -8.01 | gliogenesis | biological process | GO:0042063 | 226 | 30 | 20694 | 1406 |
Cx3cl1,Gpc1,Phgdh,Ccl3,Adora2a,Syne2,Tspo,P2ry12,Egr2,Vcan,Plpp3,Lif,Pdgfb,Ptprj,Ccl12,Map2k1,S100a8,Fpr2,Cnp,Adgrg6,Ccl2,Stat3,Csf1,Lrp8,Cdk5r1,Tlr2,Socs7,Il1b,Notch1,Pou3f1 |
| 3.332e-04 | -8.01 | protein ubiquitination | biological process | GO:0016567 | 457 | 51 | 20694 | 1406 |
Rnf19b,Cop1,Cnot4,Dtx3l,Rnf31,Malt1,Ube2e2,Socs7,Birc2,Trim21,Trim56,Birc3,Uba7,Rnf19a,Arrdc4,Med21,Bfar,Klhl25,Trim12a,Rffl,Pcgf5,Trim36,Herc6,Rnf135,Znrf3,Rnf34,Trim13,Isg15,Dtx2,Arel1,Mdm2,Sirt1,Rnf139,Spsb1,Tnfaip3,Keap1,Trim30a,Vcpip1,Znrf1,Bcor,Crbn,Ubr4,Trim12c,Fbxo4,Sde2,Peli1,Mul1,Ube2e1,Ankib1,Rnf14,Traf2 |
| 3.333e-04 | -8.01 | TIR | pfam domains | PF01582 | 20 | 7 | 18711 | 1348 |
Il18rap,Tlr9,Tlr1,Myd88,Tlr2,Tlr3,Tlr6 |
| 3.334e-04 | -8.01 | GO_CIRCULATORY_SYSTEM_PROCESS | MSigDB lists | GO_CIRCULATORY_SYSTEM_PROCESS | 342 | 46 | 15632 | 1249 |
Stat1,Nox1,Adrb2,Slc9a1,Ednrb,Lnpep,P2ry2,Nos2,Cav1,Htr2a,Gclc,Cd34,Olr1,Angpt1,Abr,Cx3cl1,Kat2b,Gclm,Kcnj2,Edn1,Sod2,Dock4,Htr2b,Vegfc,Hmox1,Ptprj,Ptafr,Cxcl10,Adora2b,Rcan1,Ptgs2,Scn1b,Pdgfb,Adora2a,Gja1,Gch1,Cd38,Mthfr,Agtrap,F11r,Icam1,Hif1a,Acvrl1,Mecp2,Plod3,Src |
| 3.337e-04 | -8.01 | regulation of transforming growth factor beta production | biological process | GO:0071634 | 34 | 9 | 20694 | 1406 |
Cd200,Cx3cl1,Ptgs2,Itgb8,Cd34,Thbs1,Met,Hif1a,Itgav |
| 3.373e-04 | -7.99 | DNA-binding transcription factor binding | molecular function | GO:0140297 | 360 | 43 | 20217 | 1400 |
Psma6,Actb,Fos,Taf4b,Rnf14,Nr4a3,Daxx,Sirt1,Tle3,Nr4a1,Notch2,Nr1h3,Hif1a,Ncoa7,Egr2,Hmga1,Mdfic,Nfkbid,Rbbp8,Ciita,Tcf4,Hhex,Stat3,Ets2,Myc,Rbl1,Jun,Src,Mier3,Psip1,Stat1,Nfkbia,Ahr,Cited2,Nek6,Arid5a,Mtdh,Dnaja1,Crkl,Ifrd1,Hdac1,Med13,Hspa1a |
| 3.403e-04 | -7.99 | GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_UP | 176 | 28 | 15632 | 1249 |
Kremen1,Tapbp,Casp3,Myc,Rai14,Tiparp,Jun,Birc2,Eif2ak2,Trmt1l,Daxx,Rbm43,Isg15,Oas2,Spen,Ifit3,Hopx,Brwd3,Dusp6,Tmem219,Notch2,Rbms1,Mitd1,Asf1a,Ifit3b,Fam111a,Endod1,Ptgir |
| 3.403e-04 | -7.99 | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_UP | MSigDB lists | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_UP | 176 | 28 | 15632 | 1249 |
Stap1,Sat1,Abcb1a,Ccnd1,Tnf,Rras2,Ciita,Crlf3,Plau,Dnase1l3,Daxx,Tlr1,Icosl,Oas2,Ube2e2,Casp8,Myo1b,Slfn4,Cd82,Slfn3,Clcf1,Pfkl,Trem1,Rtn1,Il2rg,Mefv,Clec4d,Lpar1 |
| 3.403e-04 | -7.99 | GSE6875_WT_VS_FOXP3_KO_TREG_UP | MSigDB lists | GSE6875_WT_VS_FOXP3_KO_TREG_UP | 176 | 28 | 15632 | 1249 |
Chic2,Frmd4a,Smc5,Tmod3,Hsd17b7,Arf4,Plcl2,Col27a1,Idi1,Marco,Plekha2,Golga3,Rgl1,Stat4,Sap30,H2-Aa,Sdc1,Tmem176b,Etv5,Samhd1,Tnks1bp1,Slc25a25,Cnn2,Mllt6,Treml2,Gadd45g,Slc15a3,Carhsp1 |
| 3.403e-04 | -7.99 | GSE360_L_MAJOR_VS_T_GONDII_MAC_UP | MSigDB lists | GSE360_L_MAJOR_VS_T_GONDII_MAC_UP | 176 | 28 | 15632 | 1249 |
Relb,Hck,Il15,Fabp3,Upp1,Fas,Tlk2,Optn,Pdpn,Sod2,Txnrd1,Acp2,Ptges,Il1b,Plaur,Tnip1,Nfkb2,Tnfaip2,Il18,Il12b,Ptgs2,Dtx2,Pla2g7,Stat4,Scn1b,Tlr1,Lcp2,Slc31a2 |
| 3.413e-04 | -7.98 | ZF_BBOX | prosite domains | PS50119 | 64 | 14 | 13278 | 1037 |
Trim12c,Trim30a,Mefv,Trim34a,Mid1,Trim30d,Trim12a,Trim36,Trim56,Pml,Trim14,Trim26,Trim21,Trim13 |
| 3.428e-04 | -7.98 | lymphocyte proliferation | biological process | GO:0046651 | 99 | 17 | 20694 | 1406 |
Cd180,Tnfsf4,Ifna6,Plcl2,Ifna1,Itgal,Malt1,Psmb10,Ripk2,Ifna4,Ifnb1,Il15,Azi2,Ebi3,Gja1,Ifna2,Ifna5 |
| 3.429e-04 | -7.98 | GO_ALPHA_BETA_T_CELL_DIFFERENTIATION | MSigDB lists | GO_ALPHA_BETA_T_CELL_DIFFERENTIATION | 42 | 11 | 15632 | 1249 |
Tnfsf8,Il6,Irf4,Rsad2,Syk,Batf,Relb,Ptger4,Sema4a,Il12b,Irf1 |
| 3.437e-04 | -7.98 | GO_KINASE_INHIBITOR_ACTIVITY | MSigDB lists | GO_KINASE_INHIBITOR_ACTIVITY | 85 | 17 | 15632 | 1249 |
Cdkn1a,Socs7,Prkar2b,Spred1,Socs1,Trib1,Trib3,Kat2b,Rhoh,Cdkn2d,Socs3,Nck1,Cish,Casp3,Spry2,Flrt2,Flrt3 |
| 3.437e-04 | -7.98 | GO_CYTOKINE_BINDING | MSigDB lists | GO_CYTOKINE_BINDING | 85 | 17 | 15632 | 1249 |
Thbs1,Il1rn,Itga4,Il12b,Il2rg,Cd74,Zfp36,Nrp2,Acvrl1,Il18bp,Acvr1,Vasn,Il12rb1,Ifnar1,Itgav,Ccr1,Cx3cr1 |
| 3.456e-04 | -7.97 | HUTTMANN_B_CLL_POOR_SURVIVAL_UP | MSigDB lists | HUTTMANN_B_CLL_POOR_SURVIVAL_UP | 239 | 35 | 15632 | 1249 |
Slc16a3,Gypc,Timp1,Arid5a,Zyx,Tbc1d1,Ifi44,Pnp2,Cebpd,Itga4,Abr,Mapkapk2,Atp11a,Sertad3,Pde3b,Tspo,Clcn5,Cd38,Tnfrsf1b,Dusp6,Psd4,Ppp1r15a,Itgal,Irf7,Ogfr,Btg2,Fzd1,Egln3,Pim2,Dusp5,Grina,Thbs1,Igf1r,Dnajb2,Cdkn1a |
| 3.457e-04 | -7.97 | GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 125 | 22 | 15632 | 1249 |
Pid1,Il10,Psmd10,Tnfsf14,Nfkbia,Txn1,Hsph1,Lztfl1,Nfkbie,G3bp2,Fzd1,Nfkbib,Rhoq,Ppp2r5a,Nlrp3,Nfkbil1,Parp10,Dyrk2,Zc3h12a,Keap1,Mdfic,Angpt1 |
| 3.469e-04 | -7.97 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | 70 | 15 | 15632 | 1249 |
Rhoq,Alas1,Rtn2,Bnip3,Met,Ccng2,Cebpd,Cpd,Rin2,Pla2g7,Casp4,Gem,Samhd1,Lox,Adrb2 |
| 3.470e-04 | -7.97 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP | 185 | 29 | 15632 | 1249 |
Cd86,Rnaset2a,Klf2,Tor3a,Pdk3,Cd69,Tyk2,Zfp36,Caml,Mppe1,Fam53c,Ptger4,Rnaset2b,Ppfibp2,Ralgds,Csf3r,Cd302,Rnf114,Nr4a1,Dusp1,Klf3,Cebpd,Vcan,Rab11fip1,Egr1,Itga4,Mxd1,Sla,Tspo |
| 3.470e-04 | -7.97 | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_UP | 185 | 29 | 15632 | 1249 |
Gbp3,Rtp4,Il4ra,P2ry14,Rbm43,Slc28a2,Lipe,Src,Cd302,Rhoq,Cpd,Pcx,C1ra,Sdc2,Oas1g,Smox,Pim1,Irf1,Rgs1,Fam20c,Pkp4,Vegfc,Tuba4a,Ccl5,Gem,Casp4,Tifa,Procr,Oas1a |
| 3.470e-04 | -7.97 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_NKCELL_DN | 185 | 29 | 15632 | 1249 |
Cebpd,Cers6,Fgl2,Ifnar1,Syk,Aoah,Jun,Rhbdf2,Cd302,Hck,Cd38,Rgs3,Hk3,Tpi1,Marcksl1,Nfkbil1,Rtp4,Cd180,Tyk2,Pdk3,Ccr1,Fcgr4,Irf7,Gca,Siglece,Hmox1,Socs3,Frmd4a,Lyn |
| 3.470e-04 | -7.97 | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN | 185 | 29 | 15632 | 1249 |
Cd38,Rbms2,Slc48a1,Kat2b,Spata13,Pgm1,Csrnp1,Pcx,Ctsc,Gpsm2,Plac8,Lipe,Plekhf2,Dusp16,Znrf1,Snapc1,Rgs1,Acvr1b,Smox,Fndc3a,Il12rb1,Etv6,Cnp,Cd86,Atp6v1d,Plod2,Gem,Gja1,P4ha1 |
| 3.470e-04 | -7.97 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 185 | 29 | 15632 | 1249 |
Irf7,Gna15,Itgal,Ccl5,Gdf15,Psmb8,Maff,Uba7,Oas1a,Nmi,Alas1,Inpp5b,Irf1,Psmb6,Oas1g,Trafd1,Dnajb2,Ppfibp2,Tnfsf10,Vcam1,Cd302,Ehd1,Aoah,Pcx,Phgdh,Rbl1,Tap1,Tnfrsf14,Trp53i11 |
| 3.470e-04 | -7.97 | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN | MSigDB lists | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN | 185 | 29 | 15632 | 1249 |
Ap3m2,Gtpbp2,Rnf145,Etnk1,Zc3h7a,Icosl,Tlr1,Plekha2,Ifit1bl2,Card6,Slc28a2,Herc3,Gnb4,Crlf3,Sla,Ddx58,Pigv,Fas,Irf2,B3gnt5,Ccng2,Hspa2,Sat1,Otud1,Rgs14,Bcl6,Ifit1bl1,Klf6,Parp8 |
| 3.470e-04 | -7.97 | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP | MSigDB lists | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP | 185 | 29 | 15632 | 1249 |
N4bp1,Plod3,Plekhf2,Bcl6,Tmem184b,B4galt4,Znfx1,Slc44a1,Egr2,Prokr1,Gadd45g,Glipr2,Nek6,Slco3a1,Socs1,Myd88,Batf,Atp11b,Jdp2,Rabgef1,Plod2,Gem,Il10,Flnb,Ddit4,Ptprj,Ttc39b,Arid5b,Rab20 |
| 3.470e-04 | -7.97 | GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_DN | MSigDB lists | GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_DN | 185 | 29 | 15632 | 1249 |
Wars,Etv6,Kctd12,Procr,Nrp2,Nmi,Rel,Ptch1,Eif4g2,Gfpt1,Dr1,Thbs1,Osgin2,Asb13,Map2k4,B3gnt5,D1Ertd622e,Gpr35,Katna1,Rnf24,Dse,Tagln,Rab3ip,Etv5,Gbp2,Cd74,Ppm1l,Papss2,Mxd1 |
| 3.500e-04 | -7.96 | regulation of phospholipid metabolic process | biological process | GO:1903725 | 73 | 14 | 20694 | 1406 |
Pcx,Lyn,Nod2,Fgr,Pdgfb,Flt1,Htr2b,Fabp3,Fpr2,Ldlr,Pik3r5,Htr2a,Pdgfrb,Src |
| 3.500e-04 | -7.96 | regulation of osteoclast differentiation | biological process | GO:0045670 | 73 | 14 | 20694 | 1406 |
Pilrb1,Gpr68,Il12b,Clec2d,Ccr1,Ubash3b,Tmem178,Ccl3,Tnf,Csf1,Ccl5,Ifnb1,Fos,Notch2 |
| 3.504e-04 | -7.96 | ZBP1(DAI) mediated induction of type I IFNs | REACTOME pathways | R-MMU-1606322 | 17 | 7 | 8608 | 757 |
Nfkb2,Nfkb1,Ikbkg,Zbp1,Nfkbia,Myd88,Nfkbib |
| 3.506e-04 | -7.96 | nucleic acid binding | molecular function | GO:0003676 | 3070 | 258 | 20217 | 1400 |
Egr3,Klf7,Sp110,Ifi204,Rbl1,Mcm10,Apobec3,Znfx1,Hspa1a,Kat2b,Timeless,Egr1,Ifi209,Tal2,Tcea1,Plagl1,Mndal,Dnase1l3,Klf3,Arid5a,Zfp40,Mafg,Stau1,Arid5b,Aebp2,Oas2,H3f3b,Sp100,Rbpms,Ythdf1,Zeb1,Radx,Cgas,Dach1,Trim30a,Nr4a3,Eif4g2,Nfkb2,Tiparp,Ciita,Zup1,Ifi208,Cnp,Prpf4,Batf2,Tut7,Pnpt1,Ctu1,Isg20,Gtpbp2,Oas1g,Tnfaip3,Magohb,Hmga1,Zc3h7a,Ifit1bl1,Stat2,Zc3hav1,Zfp800,Ahr,Crlf3,Zcchc2,Maff,Myc,Oas1b,Slfn8,Stat3,Kdm6b,G3bp2,Etv3,Stat1,Mier3,Zbtb5,Psip1,Rcan1,Cebpd,Aff1,Ifi211,Swap70,Fosb,Dcp2,Nfkb1,Mdm2,Pbx1,Atm,Prdm1,Mafk,Cers6,Igf2bp2,Nr4a1,Nr1h3,Sirt1,Nlrc5,Chd9,Ddx4,Spen,Morc3,Ier2,Max,Prdx5,Bcor,Smg7,Rnf114,Sp140,Ifit1,Sap30,Spic,Oas3,Ikzf1,Gfi1,Denr,Slpi,Sod2,Ifi205,Ifit2,Ahrr,Etv5,Ifi203,Rrs1,Egr2,Rbm43,Nlrp3,Ift57,Samhd1,Nr3c1,Ddx60,Junb,Sphk1,Ddx58,Klf8,Nfil3,Ifi213,Rbms2,Jun,Phf6,Ets2,Zfp36,Csrnp1,Larp1,Slfn9,Tlr9,Notch1,Irf2,Foxp4,Trim21,Atf3,Dr1,Lipe,Tshz1,Carhsp1,Noct,Bbx,Zfp281,Mtdh,Shfl,Hopx,Hlx,Klf6,Trmt1l,Nupr1,Oas1a,Jdp2,Polr2g,Helz2,Bcl6,Jarid2,Fos,Mxd1,Psma6,Ifi214,Mycl,Rabgef1,Zfp513,Kdm5b,Rbbp8,Batf,Setdb2,Pou2f2,Ascc3,Cpeb4,Lhx2,Nfxl1,Oasl2,Ranbp2,Stat4,Hif1a,Pcgf5,Ifi207,Top3a,Aim2,Ago3,Irf1,Hivep2,Adar,Mov10,Rfx5,Tnf,Jmjd6,Mcm6,Eno1,N4bp1,Ifih1,Eif2ak2,Hdac1,Hmgn3,Casz1,Cyfip1,Rars,Pou3f1,Mcm9,Arid4a,Dhx58,Lmo4,Xrn1,Ifit1bl2,Tra2a,Irf7,Sde2,Ep400,9130023H24Rik,Dek,Tdrd7,Tlr3,Zfp945,Oasl1,Hivep3,Zfp319,Prdm9,Taf4b,Mecp2,Etv6,Cnot4,Tfec,Klf2,Plagl2,Zbp1,Ankrd17,Irf8,Sbds,Fubp1,Stat5a,Hmga2,Endod1,Zc3h12a,Hhex,Tcf4,Pml,Tet2,Irf4,Relb,Hinfp,Rbms1,Zhx2,Plscr1,Snapc1,Nxf1,Marf1,Rel |
| 3.514e-04 | -7.95 | SRF_C | MSigDB lists | SRF_C | 194 | 30 | 15632 | 1249 |
Thbs1,Actb,Dnajb4,Dusp5,Egr3,Ppp2r3a,G3bp2,Pdlim7,Fosb,Ptch1,Osm,Myo1b,Dcun1d3,Dusp6,Junb,Tle3,Rgs3,Egr1,Zfp513,Ier2,Gadd45g,Acvr1,Egr2,Dusp2,Tank,Fos,Tagln,Klf6,Cnn2,Nr4a1 |
| 3.514e-04 | -7.95 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | 194 | 30 | 15632 | 1249 |
Ddx58,Tmem176b,Gnb4,Birc2,Casp1,Zfp800,Ift57,Parp9,Gpr35,Lrch1,Il6,Trib3,Frmd4a,Dram1,Mmp9,Tfec,Cmpk2,Cflar,Cxcl1,Rgs1,Col27a1,Asah2,Lad1,Adap2,Snx2,Slamf9,Met,Pstpip2,Fabp7,Stxbp3 |
| 3.531e-04 | -7.95 | GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_UP | MSigDB lists | GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_UP | 159 | 26 | 15632 | 1249 |
Dusp2,Tbc1d1,Gpr68,Scarf1,Treml2,Phlpp1,Slc7a11,Tnf,Gramd1a,Nlrc5,Trip10,Sla,Rbms2,Chmp4b,Tlr6,Lrp8,Pgm1,Pdlim7,Dcp1a,Myadm,Tuba4a,4930523C07Rik,Tnip1,Fscn1,Cdkn1a,Stard7 |
| 3.531e-04 | -7.95 | GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP | MSigDB lists | GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP | 159 | 26 | 15632 | 1249 |
Endod1,Ifi204,Rnf145,Epsti1,Dusp16,Myadm,Ppp1r15b,Mndal,Samsn1,Flrt2,Daam1,Ifi208,Ifi211,Ifi203,Itga4,Arg2,Ifi214,Ifi207,Ifi213,Ifi205,Ifi209,Stap1,Peli1,Sat1,Ifnb1,Lztfl1 |
| 3.549e-04 | -7.94 | MODULE_361 | MSigDB lists | MODULE_361 | 117 | 21 | 15632 | 1249 |
Cd200,Kcna3,Fgr,Il4ra,Rcsd1,Plcl2,Cmklr1,Adam19,Tnfaip2,Hvcn1,5430427O19Rik,Plac8,Sp140,Abcc5,Irf8,Flrt2,Heatr6,Btg2,Mecp2,Spint2,Rsad2 |
| 3.549e-04 | -7.94 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_CIS | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_CIS | 117 | 21 | 15632 | 1249 |
Ifi208,Cnn3,Ctsc,Ifi211,Ifi203,Il12rb1,Csrp1,Ifi213,Mndal,Ifi209,Hdc,Ifi205,Gnb4,Ifi207,Psmb6,Ifi214,Agtrap,F11r,Ifi204,Rcn1,Ccnd2 |
| 3.558e-04 | -7.94 | ATTACAT_MIR3803P | MSigDB lists | ATTACAT_MIR3803P | 93 | 18 | 15632 | 1249 |
Eif4g2,Trim36,Hivep2,Nampt,Itgav,Flrt2,Rab21,Snx2,Zfp800,Cnot4,Cpeb4,Herc6,Irf2,Bcor,Fndc3a,Nr4a3,Kitl,Apaf1 |
| 3.566e-04 | -7.94 | ubiquitin-like protein transferase activity | molecular function | GO:0019787 | 394 | 46 | 20217 | 1400 |
Trim13,Uba7,Cop1,Ankib1,Rnf24,Rnf135,Fbxo4,Trim12c,Ube2f,Trim21,Dtx3l,Mdm2,Trim36,Malt1,Rnf145,Znrf3,Ube2e2,Med21,Rnf19b,Rffl,Rnf139,Cnot4,Bcor,Trim30a,Rabgef1,Arel1,Rnf14,Trim12a,Rnf31,Birc3,Ube2l6,Mul1,Traf2,Rnf34,Herc6,Peli1,Ubr4,Ranbp2,Birc2,Znrf1,Trim56,Bfar,Ube2e1,Tnfaip3,Rnf19a,Egr2 |
| 3.614e-04 | -7.93 | cell-substrate junction | cellular component | GO:0030055 | 166 | 24 | 20747 | 1409 |
Irf2,Evl,Vasp,Itgav,Ezr,Flnb,Map2k1,Zyx,Ptk2,Dst,Keap1,Itga5,Pdlim7,Itgb8,Asap3,Sdc4,Cav1,Syne2,Map4k4,Prag1,Flrt3,Flrt2,Hck,Jak2 |
| 3.617e-04 | -7.92 | positive regulation of T cell mediated cytotoxicity | biological process | GO:0001916 | 49 | 11 | 20694 | 1406 |
H2-T24,H2-M2,H2-T10,Pvr,H2-Q6,H2-T22,Il12b,Nectin2,H2-Q7,Tap2,H2-Q4 |
| 3.638e-04 | -7.92 | protein kinase regulator activity | molecular function | GO:0019887 | 163 | 24 | 20217 | 1400 |
Cdkn2d,Cdkn1a,Rgcc,Ccne1,Trib3,Ccnj,Daxx,Casp3,Spred1,Map2k1,Nos2,Kat2b,Ccnd2,Ccng2,Prkar2b,Spry2,Irgm2,Mtcp1,Cdk5r1,Nck1,Ccl5,Ccnd1,Trib1,Lgals9 |
| 3.647e-04 | -7.92 | FURUKAWA_DUSP6_TARGETS_PCI35_UP | MSigDB lists | FURUKAWA_DUSP6_TARGETS_PCI35_UP | 63 | 14 | 15632 | 1249 |
Herc6,Hmox1,Phf11d,Tapbpl,Aldh1b1,Rtp4,Phf11a,Phf11c,Phf11b,Psmb9,Slc15a3,AA467197,Dusp4,Parp9 |
| 3.647e-04 | -7.92 | GO_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS | 63 | 14 | 15632 | 1249 |
Ldlr,Htr2a,Htr2b,Ptk2,Lyn,Fabp3,Fgr,Pdgfb,Nod2,Src,Flt1,Pik3r5,Pik3r6,Pdgfrb |
| 3.647e-04 | -7.92 | chr1q22 | MSigDB lists | chr1q22 | 63 | 14 | 15632 | 1249 |
Igsf9,Ifi213,Ifi209,Mndal,Ifi205,Ifi208,Ifi211,Ifi203,Sele,Aim2,Ifi214,Sema4a,Ifi204,Ifi207 |
| 3.651e-04 | -7.92 | GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP | MSigDB lists | GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP | 168 | 27 | 15632 | 1249 |
Serpinb9,Ptgs2,Clec5a,Filip1l,Ebi3,Egr3,Atp10a,Pmepa1,Il1b,Chd9,Map4k4,Clic5,Maff,Cxcl2,Inhba,Slc25a12,Ddit4,Tpx2,Traf1,Il1a,Egr1,Atf3,Gclc,Slc2a1,Mtus1,Itpr1,Ppfia3 |
| 3.657e-04 | -7.91 | EGR_N | interpro domains | IPR021849 | 3 | 3 | 19984 | 1430 |
Egr1,Egr3,Egr2 |
| 3.657e-04 | -7.91 | L_AA_transporter | interpro domains | IPR004760 | 3 | 3 | 19984 | 1430 |
Slc7a5,Slc7a11,Slc7a8 |
| 3.657e-04 | -7.91 | DUF2075 | interpro domains | IPR018647 | 3 | 3 | 19984 | 1430 |
Slfn9,Slfn5,Slfn8 |
| 3.657e-04 | -7.91 | RIG-I_C | interpro domains | IPR041204 | 3 | 3 | 19984 | 1430 |
Dhx58,Ddx58,Ifih1 |
| 3.657e-04 | -7.91 | RLR_CTR | interpro domains | IPR021673 | 3 | 3 | 19984 | 1430 |
Ifih1,Dhx58,Ddx58 |
| 3.657e-04 | -7.91 | PIM1/2/3 | interpro domains | IPR017348 | 3 | 3 | 19984 | 1430 |
Pim2,Pim1,Pim3 |
| 3.657e-04 | -7.91 | RLR_C_sf | interpro domains | IPR038557 | 3 | 3 | 19984 | 1430 |
Ddx58,Dhx58,Ifih1 |
| 3.664e-04 | -7.91 | CKAP4 (cytoskeleton associated protein 4) | protein interactions | 10970 | 8 | 5 | 7778 | 753 |
Ktn1,Chmp4b,Ksr1,Junb,Rmdn3 |
| 3.664e-04 | -7.91 | Hes1 (hes family bHLH transcription factor 1) | protein interactions | 15205 | 8 | 5 | 7778 | 753 |
Stat3,Sirt1,Jak2,Kdm6b,Rcan1 |
| 3.676e-04 | -7.91 | BOYLAN_MULTIPLE_MYELOMA_C_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_DN | 49 | 12 | 15632 | 1249 |
Rab20,Slc30a1,Irs2,Klf7,Rgs1,Jun,Plod2,Klf6,Cers6,Egln3,Abcb1a,Sat1 |
| 3.676e-04 | -7.91 | GO_SKELETAL_MUSCLE_CELL_DIFFERENTIATION | MSigDB lists | GO_SKELETAL_MUSCLE_CELL_DIFFERENTIATION | 49 | 12 | 15632 | 1249 |
Atf3,Nupr1,Egr1,Plagl1,Fos,Bcl9,Sap30,Btg2,Egr2,Notch1,Hivep3,Maff |
| 3.680e-04 | -7.91 | KOYAMA_SEMA3B_TARGETS_UP | MSigDB lists | KOYAMA_SEMA3B_TARGETS_UP | 249 | 36 | 15632 | 1249 |
Dcbld2,Fmnl2,Plaur,Thbs1,Adrb2,Kif3c,Tgfbi,Kif5c,Pcgf5,Itpkc,Hk2,Antxr1,Ddit4,Ube2l6,Ksr1,Serpine1,Dmwd,Plekhg1,Ltbp2,Gdf15,Psmb8,Slc31a2,Tsku,Stau1,1600014C10Rik,Plau,Gmppb,Mid1,Minpp1,Ctsc,Casz1,Cd302,Swap70,Sp140,Rapgef5,Axl |
| 3.701e-04 | -7.90 | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | MSigDB lists | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | 277 | 39 | 15632 | 1249 |
Ccr1,Ccl5,Ednrb,P2ry2,Cysltr2,Gpr132,Adora2a,Cxcl2,Ptger4,Ptgir,C3,Lpar1,Adora2b,Fpr1,Ptafr,Cxcl10,Adrb2,Cxcl1,Ccl4,Xcr1,Hcar2,Pf4,Htr2b,Cx3cr1,Ccl12,Gpr18,P2ry12,P2ry13,Prokr1,Ccr3,Edn1,S1pr2,Gpr68,Fpr2,Ccl22,Cx3cl1,P2ry14,Htr2a,Ccl3 |
| 3.730e-04 | -7.89 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | 134 | 23 | 15632 | 1249 |
Notch1,Samhd1,Col4a2,Rbms2,Atp11a,Papss2,Isg15,Slco3a1,Atf3,Nupr1,Pnp2,Fos,Cited2,Plac8,Dusp1,Phyh,Ifi35,Socs3,St3gal5,Slpi,Sema3c,Klf2,Snx10 |
| 3.731e-04 | -7.89 | KEGG_ACUTE_MYELOID_LEUKEMIA | MSigDB lists | KEGG_ACUTE_MYELOID_LEUKEMIA | 56 | 13 | 15632 | 1249 |
Stat5a,Pim2,Pik3r5,Nfkb1,Pml,Ikbkg,Pim1,Map2k1,Pik3cd,Stat3,Akt3,Myc,Ccnd1 |
| 3.731e-04 | -7.89 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | 56 | 13 | 15632 | 1249 |
Dach1,Cdyl,Sema3c,Calcrl,Lmo4,Pcdh7,Tmeff1,Pbx1,Kitl,Gng11,Mdfic,Prkar2b,Stx11 |
| 3.731e-04 | -7.89 | AMIT_EGF_RESPONSE_240_HELA | MSigDB lists | AMIT_EGF_RESPONSE_240_HELA | 56 | 13 | 15632 | 1249 |
Plk2,Ezr,Ehd1,Slc7a11,Txnrd1,Zeb1,Cd55,Ell2,Lrp8,Sdc4,Rbms1,Pcdh7,Thbs1 |
| 3.731e-04 | -7.89 | RIG-I_C-RD | pfam domains | PF11648 | 3 | 3 | 18711 | 1348 |
Dhx58,Ifih1,Ddx58 |
| 3.731e-04 | -7.89 | RIG-I_C | pfam domains | PF18119 | 3 | 3 | 18711 | 1348 |
Ddx58,Dhx58,Ifih1 |
| 3.731e-04 | -7.89 | DUF3446 | pfam domains | PF11928 | 3 | 3 | 18711 | 1348 |
Egr3,Egr2,Egr1 |
| 3.731e-04 | -7.89 | DUF2075 | pfam domains | PF09848 | 3 | 3 | 18711 | 1348 |
Slfn5,Slfn8,Slfn9 |
| 3.734e-04 | -7.89 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032436 | 82 | 15 | 20694 | 1406 |
Rnf19b,Cop1,Trib3,Gclc,Rnf19a,Mdm2,Plk2,Hspa1b,Dnajb2,Trib1,Psmd10,Ankib1,Plk3,Rnf14,Hspa1a |
| 3.741e-04 | -7.89 | GO_CELLULAR_RESPONSE_TO_TOXIC_SUBSTANCE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_TOXIC_SUBSTANCE | 24 | 8 | 15632 | 1249 |
Abtb2,Hif1a,Ppp1r15a,Pla2g4a,Rab10,Slc9a1,Mdm2,Il1b |
| 3.741e-04 | -7.89 | ONO_AML1_TARGETS_UP | MSigDB lists | ONO_AML1_TARGETS_UP | 24 | 8 | 15632 | 1249 |
Cd38,Mecp2,Slamf7,Fos,Sema4a,Jun,P2ry14,Gadd45b |
| 3.741e-04 | -7.89 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_ANTIGEN | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_ANTIGEN | 24 | 8 | 15632 | 1249 |
H2-Q4,H2-Q7,Tap2,Cd74,H2-Q6,Abcb1a,Tapbp,Tap1 |
| 3.741e-04 | -7.89 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP | 24 | 8 | 15632 | 1249 |
Dusp16,Maff,Ppp1r15a,Ptgs2,Dnaja1,Mafg,Klf6,Csrnp1 |
| 3.741e-04 | -7.89 | ST_INTERLEUKIN_4_PATHWAY | MSigDB lists | ST_INTERLEUKIN_4_PATHWAY | 24 | 8 | 15632 | 1249 |
Akt3,Jak2,Cish,Tyk2,Src,Il13ra1,Il4ra,Il2rg |
| 3.741e-04 | -7.89 | B cell receptor signaling pathway | KEGG pathways | ko04662 | 70 | 16 | 7931 | 713 |
Map2k1,Ifitm1,Pik3cd,Nfkbia,Ikbkg,Rac3,Fcgr2b,Malt1,Lyn,Syk,Nfkbib,Nfkbie,Jun,Nfkb1,Fos,Akt3 |
| 3.741e-04 | -7.89 | B cell receptor signaling pathway | KEGG pathways | mmu04662 | 70 | 16 | 7931 | 713 |
Nfkb1,Jun,Nfkbie,Akt3,Fos,Ifitm1,Pik3cd,Map2k1,Ikbkg,Nfkbia,Syk,Nfkbib,Lyn,Rac3,Fcgr2b,Malt1 |
| 3.741e-04 | -7.89 | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_DN | 177 | 28 | 15632 | 1249 |
Gsr,Mllt6,Itgb8,Tank,Cd40,Dnaja1,Znfx1,Pik3r5,Hivep2,Dync1h1,Crim1,Pim3,Il1a,Kmo,Hk2,Ccrl2,Med13,Ampd3,Trim21,Zc3h12c,Myo1b,Il1b,Abcc1,Mob3c,Cd82,Cflar,C3,Itga5 |
| 3.741e-04 | -7.89 | GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP | 177 | 28 | 15632 | 1249 |
Rin2,Optn,Ccr3,1110038F14Rik,Myc,Ezr,Parp8,Psip1,Sod2,Etv5,Rbms2,Cutc,Gys1,Cyth3,Arl4a,Traf1,Aim2,Tlr6,Ksr1,Ube2l6,Daam1,Casp4,Pdk3,Igf2bp2,Whamm,Acsl5,Mtmr14,Dram1 |
| 3.741e-04 | -7.89 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_DN | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_DN | 177 | 28 | 15632 | 1249 |
Prdm1,Gbe1,St3gal6,Sass6,Slamf7,Cst7,Plac8,Ptpn2,Tiparp,Fcgr2b,Tbc1d1,Ifrd1,Tmod3,Dyrk2,Ier3,Cdc42ep4,St7,Dnajb4,Rcn1,Adam19,Ust,5430427O19Rik,Myadm,Ccl5,Plek,Eef1e1,Il18rap,Smpdl3b |
| 3.750e-04 | -7.89 | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_DN | MSigDB lists | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_DN | 151 | 25 | 15632 | 1249 |
Kat2b,Znrf3,Tmem176b,Rab3ip,Irak3,Acpp,Rhbdf2,Spn,Klf3,Treml2,Dock10,Ikzf1,Uaca,Tmod3,Filip1l,Osbpl3,Znrf1,Rbms1,Ldlr,Sec24a,Sipa1l1,Slc4a7,Map4k4,Syne2,Rap1gap2 |
| 3.771e-04 | -7.88 | KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY | 78 | 16 | 15632 | 1249 |
Lyn,Pik3cd,Malt1,Rac3,Nfkbie,Akt3,Fcgr2b,Nfkbib,Fos,Map2k1,Jun,Nfkbia,Nfkb1,Ikbkg,Pik3r5,Syk |
| 3.771e-04 | -7.88 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | MSigDB lists | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | 78 | 16 | 15632 | 1249 |
Psmb8,H2-Q4,Lnpep,Itgav,H2-Q6,Tap2,Psmb9,Psmd10,Psme2,Psma6,H2-Q7,Psme1,Psmb6,Psmb10,Fcgr1,Tap1 |
| 3.787e-04 | -7.88 | BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN | 36 | 10 | 15632 | 1249 |
Glrx,Gclm,Abcb1a,Slc16a1,Gclc,Kat2b,Lap3,Gbe1,Tlr3,Spsb1 |
| 3.787e-04 | -7.88 | GENTILE_UV_RESPONSE_CLUSTER_D7 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D7 | 36 | 10 | 15632 | 1249 |
Rbms1,Nr3c1,Rras2,Cebpd,Met,Rars,Morc3,Trip10,Casp8,Il4ra |
| 3.787e-04 | -7.88 | GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | 36 | 10 | 15632 | 1249 |
Tnfsf4,Hlx,Bcl6,Il4ra,Ptpn2,Irf1,Cd74,Ifnb1,Inhba,Nfkbid |
| 3.800e-04 | -7.88 | GO_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | 268 | 38 | 15632 | 1249 |
Acvrl1,Ift57,Nod2,Errfi1,Ccnd1,Kdm5b,Il6,Myc,Ccr3,Jun,Ccl12,Stat5a,Nr4a1,Angpt1,Tnfaip3,Notch1,Bmp2,Sav1,Plau,Intu,Hif1a,Sirt1,Rictor,Htra1,Nrp2,Pdgfb,Ptch1,Cav1,Gja1,Ccl5,Ednrb,Htr2b,Vegfc,Kdr,Thbs1,Nr4a3,Stat1,Egr3 |
| 3.804e-04 | -7.87 | GSE15330_WT_VS_IKAROS_KO_HSC_UP | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_HSC_UP | 186 | 29 | 15632 | 1249 |
Parp12,Rab10,Pstpip2,Chic2,Nr4a3,Ifi35,Fam53c,Smc5,Fndc3a,Plaur,Arf4,Dnaja1,Jun,Parp8,Klf3,Ddhd1,Syk,Mdm2,Errfi1,Acvrl1,Abcb1a,Ly75,Pde1b,Phip,Hif1a,Arl4a,Mark2,Samhd1,Sgk3 |
| 3.804e-04 | -7.87 | GSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP | MSigDB lists | GSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP | 186 | 29 | 15632 | 1249 |
Brwd3,Dmwd,Lmo4,Golga3,Ascc3,Srxn1,Kif5c,Rnf19b,Pdzd11,Tapbpl,Cxcl10,Tgfbi,Slamf8,Tnfsf10,Pik3r5,Psip1,Cenpe,Gpsm2,Cish,Phgdh,Cpd,Cox17,Ier2,Cx3cl1,P2ry14,Sphk1,Il1a,Tnfrsf8,F10 |
| 3.804e-04 | -7.87 | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN | 186 | 29 | 15632 | 1249 |
Klf2,Pdgfb,Zeb1,Psme2,Stat4,Dgka,Traf3ip2,Tnip1,Wdr43,Abcc5,Sbds,Plekha5,Bcl2l11,Cst7,Phldb1,Ppp1r14b,Jun,Tlk2,Mecp2,Evl,Mcoln2,Usp18,Ccnd2,Il4ra,Gbe1,Traf1,Sell,Traf5,Crlf3 |
| 3.804e-04 | -7.87 | GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_UP | MSigDB lists | GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_UP | 186 | 29 | 15632 | 1249 |
Fcgr2b,Plekhf2,Casp1,Acpp,Slamf7,Sgk3,Ciita,Tle3,Dnase1l3,Nupr1,Prdm1,St3gal6,Fgr,Ccl22,Rasgrp1,Stat4,Casp4,Lcn2,Map2k1,Il10,Hopx,Ccl4,Tnfsf10,Adam19,Actb,Rbms1,Plaur,Acsl1,Ier3 |
| 3.821e-04 | -7.87 | protein complex oligomerization | biological process | GO:0051259 | 588 | 62 | 20694 | 1406 |
Ikbke,Lrp4,Kcna3,Vasp,Tifa,Marcks,Traf2,G3bp2,Map2k1,Samhd1,Lcn2,Kcnj2,Prnp,Keap1,Ripk3,Hmox1,Cycs,Cav1,Nlrc4,Gja1,Itpr1,Sqstm1,Pdss1,Chmp4b,Kctd12,Txnrd1,Mmp9,Zc3h12a,Lrrc8c,Optn,Mlkl,Snx2,Pnpt1,Ehd1,Sod2,Gfpt1,Mcoln2,Acpp,Gch1,Rasgrp1,Birc3,Angpt1,Ikzf1,Apaf1,Evl,Me1,Fas,Ccl5,Jmjd6,Nod2,Homer1,Birc2,Trim21,Cutc,Stxbp3,Igf1r,Pfkl,Dgkh,Agrn,Cd74,Gsdmd,Malt1 |
| 3.843e-04 | -7.86 | GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_DN | MSigDB lists | GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_DN | 195 | 30 | 15632 | 1249 |
Tnfsf14,4930523C07Rik,Dach1,Brwd3,Card6,Nfkb1,Ksr1,Il12b,Serpinb9,Ebi3,Cd200,Pcgf5,Socs3,Clcf1,Cflar,Adam19,Swap70,Tet2,D16Ertd472e,Jun,Gadd45b,Cst7,Rapgef5,Chst11,Mllt6,Aebp2,Fut8,Il6,Batf,Lipg |
| 3.852e-04 | -7.86 | cell cycle arrest | biological process | GO:0007050 | 91 | 16 | 20694 | 1406 |
Inhba,Notch2,Cdkn2d,Pnpt1,Rgcc,Slfn1,Atm,Cdkn1a,Pml,Il12b,Map2k1,Notch1,Thbs1,Myc,Whamm,Irf1 |
| 3.874e-04 | -7.86 | mononuclear cell proliferation | biological process | GO:0032943 | 100 | 17 | 20694 | 1406 |
Plcl2,Ifna6,Psmb10,Ifna1,Itgal,Malt1,Cd180,Tnfsf4,Ebi3,Azi2,Ifna2,Ifna5,Gja1,Ifna4,Ifnb1,Ripk2,Il15 |
| 3.879e-04 | -7.85 | GO_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS | 126 | 22 | 15632 | 1249 |
Il1b,Htr2b,Htr2a,Ldlr,Ptgs2,Nr4a3,Fabp3,Fgr,Adrb2,Nsmaf,Lyn,Nr1h3,Irs2,Ptk2,Nod2,Pdgfb,Pla2g4a,Prkce,Pdgfrb,Flt1,Tnf,Src |
| 3.884e-04 | -7.85 | regulation of cytosolic calcium ion concentration | biological process | GO:0051480 | 358 | 42 | 20694 | 1406 |
Swap70,Ednrb,Fpr1,Htr2a,Il1b,Ccr3,Ptgir,Itpr1,Gja1,Htr2b,Itgav,Ccrl2,Jak2,Edn1,Marcksl1,Gpr18,Cxcl2,Cav1,Cxcl3,Gpr35,Cd38,Adrb2,Cacnb3,Cx3cr1,Hap1,Fpr2,Xcr1,Ccr1,Cxcl10,Cmklr1,Kdr,Ero1l,Tmem178,Atp2b4,Ptger4,Cx3cl1,P2ry2,Ccl3,Gna15,Lpar1,Cacna1d,Cxcl1 |
| 3.903e-04 | -7.85 | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN | 160 | 26 | 15632 | 1249 |
Mapkapk2,Hlx,Trim13,Slamf7,Cd83,Daxx,Crim1,Dock4,Mrpl52,Rab21,Tbc1d1,Tra2a,Ppa1,Rnf19b,Casp7,Nr4a3,Lyn,Usp42,Rcan1,Plat,Mier3,Birc3,Sema3c,Bcl9,Hivep3,Ccrl2 |
| 3.903e-04 | -7.85 | GSE29618_BCELL_VS_MONOCYTE_UP | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_UP | 160 | 26 | 15632 | 1249 |
Pim2,Odc1,Kcna3,Arid5b,Adam19,Zhx2,Birc3,Atm,Isg20,Mmd,Cd69,Rasgrp1,Evl,Klf8,Il4ra,Pikfyve,Traf5,Rras2,Ezr,Sp140,Swap70,Tcf4,Slc2a1,Myc,Stap1,Ift57 |
| 3.949e-04 | -7.84 | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION | 30 | 9 | 15632 | 1249 |
Il12b,Tlr2,Cd40,Irf8,Irf1,Ripk2,Tlr3,Tlr9,Tnfsf4 |
| 3.949e-04 | -7.84 | GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION | 30 | 9 | 15632 | 1249 |
Dock4,P2ry2,Pdgfrb,Lpar1,Ccl5,Src,Ptger4,Pdgfb,Plau |
| 3.949e-04 | -7.84 | DOANE_BREAST_CANCER_CLASSES_DN | MSigDB lists | DOANE_BREAST_CANCER_CLASSES_DN | 30 | 9 | 15632 | 1249 |
Plaur,Cebpd,Fscn1,Sgcb,Dek,Slc16a1,Atp11a,Plod2,Lmo4 |
| 3.949e-04 | -7.84 | HALLMARK_NOTCH_SIGNALING | MSigDB lists | HALLMARK_NOTCH_SIGNALING | 30 | 9 | 15632 | 1249 |
Ccnd1,Notch1,Jag1,Fzd1,Sap30,Notch2,Fzd5,St3gal6,Dtx2 |
| 3.951e-04 | -7.84 | phagocytosis | biological process | GO:0006909 | 128 | 20 | 20694 | 1406 |
Jmjd6,Itgav,Msr1,Marco,Cd302,Ldlr,Rac3,Nr1h3,Xkr8,Fcgr2b,Axl,Irf8,Rab20,Itgal,Myd88,Hck,Met,Fcgr1,Thbs1,Treml4 |
| 3.951e-04 | -7.84 | regulation of cell cycle G1/S phase transition | biological process | GO:1902806 | 128 | 20 | 20694 | 1406 |
Mdm2,Psme1,Cdkn1a,Ccne1,Pml,Casp2,Ccl12,Ankrd17,Ube2e2,Rbl1,Dcun1d3,Atp2b4,Psme2,Ccnd2,Cdkn2d,Plk3,Ccnd1,Pdpn,Slfn1,Rgcc |
| 3.954e-04 | -7.84 | muscle structure development | biological process | GO:0061061 | 495 | 54 | 20694 | 1406 |
Flnb,Maff,Sdc1,Cav1,Sirt1,Csrp1,Btg2,Sgcb,Ppp2r3a,Notch1,Cd164,Lif,Pdgfb,Tmod3,Lox,Psma6,Fos,Cflar,Sap30,Bcl9,Hlx,Bmp2,Casp1,Sema4c,Homer1,Ifrd1,Nupr1,Egr1,Uchl1,Pdlim7,Ednrb,Pdgfrb,Arid5b,Myc,Hivep3,Kdm6b,Rcan1,Egr2,Cacybp,Cited2,Mecp2,Plagl1,Fzd1,Serp1,Angpt1,Met,Slc9a1,H3f3b,Map2k4,Nr4a1,Hinfp,Acvr1,Asf1a,Atf3 |
| 3.970e-04 | -7.83 | GO_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | 86 | 17 | 15632 | 1249 |
Serpine1,Cx3cr1,Ccl12,Pdgfb,Sema4a,Cxcl10,Adrb2,Ptger4,Hhex,Lif,Stat1,Pml,Notch1,Pf4,Col4a2,Thbs1,Pde3b |
| 4.018e-04 | -7.82 | entry into cell of other organism involved in symbiotic interaction | biological process | GO:0051806 | 42 | 10 | 20694 | 1406 |
Nectin2,Cd55,Axl,Tnfrsf14,Cav1,Pvr,Nectin4,Clec5a,Itgav,Cd300lf |
| 4.018e-04 | -7.82 | glial cell migration | biological process | GO:0008347 | 42 | 10 | 20694 | 1406 |
Socs7,Ccl2,Vcan,Syne2,Tspo,P2ry12,Ccl12,Lrp8,Cdk5r1,Ccl3 |
| 4.018e-04 | -7.82 | entry into host | biological process | GO:0044409 | 42 | 10 | 20694 | 1406 |
Nectin2,Cd55,Axl,Tnfrsf14,Pvr,Cav1,Nectin4,Clec5a,Itgav,Cd300lf |
| 4.018e-04 | -7.82 | entry into other organism involved in symbiotic interaction | biological process | GO:0051828 | 42 | 10 | 20694 | 1406 |
Nectin2,Cav1,Tnfrsf14,Pvr,Axl,Cd55,Itgav,Nectin4,Clec5a,Cd300lf |
| 4.018e-04 | -7.82 | regulation of monooxygenase activity | biological process | GO:0032768 | 42 | 10 | 20694 | 1406 |
Cav1,Nfkb1,Nod1,Gfi1,Gch1,Tnf,Il1b,Atp2b4,Htr2b,Arg2 |
| 4.018e-04 | -7.82 | entry into host cell | biological process | GO:0030260 | 42 | 10 | 20694 | 1406 |
Itgav,Clec5a,Nectin4,Cd300lf,Nectin2,Axl,Cd55,Cav1,Pvr,Tnfrsf14 |
| 4.022e-04 | -7.82 | ERB2_UP.V1_DN | MSigDB lists | ERB2_UP.V1_DN | 169 | 27 | 15632 | 1249 |
Irf7,Slc7a2,Cav1,Ifit1bl2,Oas2,Rasgrp1,Oas1a,Flnb,Kif5c,Oas1g,Egr3,Herc6,Wdr43,Prkar2b,Igf1r,Zcchc2,Jak2,Rbbp8,Ass1,Cenpe,Ifit1bl1,Ift57,Myc,Ifi44,Ifih1,Ddx58,Ddx60 |
| 4.022e-04 | -7.82 | WANG_CLIM2_TARGETS_DN | MSigDB lists | WANG_CLIM2_TARGETS_DN | 169 | 27 | 15632 | 1249 |
Etnk1,Hmgcs1,St3gal1,Stat1,Phf11d,Whamm,Idi1,Gca,Asf1a,Ifit1bl2,Rnf14,Ppp4r2,Stxbp3,Jag1,Fas,Rars,Csrnp1,Zfp281,Isg15,Phf11a,Daxx,Klf7,Phf11c,Ifit1bl1,Phf11b,Ccdc86,Ifrd1 |
| 4.025e-04 | -7.82 | BIRC2 (baculoviral IAP repeat containing 2) | protein interactions | 329 | 5 | 4 | 7778 | 753 |
Junb,Traf1,Traf2,Tnfrsf1b |
| 4.025e-04 | -7.82 | Pik3cg (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma) | protein interactions | 30955 | 5 | 4 | 7778 | 753 |
Pik3r6,Pik3r5,Pde3b,Pik3cd |
| 4.051e-04 | -7.81 | regulation of muscle hypertrophy | biological process | GO:0014743 | 74 | 14 | 20694 | 1406 |
Tnfrsf1b,Sirt1,Pde5a,Tomm70a,Slc9a1,Nr3c1,Notch1,Trip10,Jarid2,Ptk2,Edn1,Errfi1,Atp2b4,Nr4a3 |
| 4.052e-04 | -7.81 | lymphocyte costimulation | biological process | GO:0031294 | 28 | 8 | 20694 | 1406 |
Cav1,Tnfrsf14,Tnfsf14,Cd86,Tnfsf4,Cd274,Spn,Cd80 |
| 4.052e-04 | -7.81 | purinergic receptor signaling pathway | biological process | GO:0035587 | 28 | 8 | 20694 | 1406 |
Adora2b,P2ry12,P2ry13,Hcar2,Adora2a,P2ry2,P2ry14,Ptafr |
| 4.055e-04 | -7.81 | Fadd (Fas (TNFRSF6)-associated via death domain) | protein interactions | 14082 | 16 | 7 | 7778 | 753 |
Tnfaip3,Tnf,Cflar,Casp8,Mlkl,Birc3,Fas |
| 4.072e-04 | -7.81 | DAP12 signaling | REACTOME pathways | R-MMU-2424491 | 307 | 45 | 8608 | 757 |
Psmb10,Psmd10,Phlpp1,Klrk1,Pik3cd,Psmb9,Lcp2,Spred1,Angpt1,Psme2b,Phlpp2,Src,Prkce,Ppp2r1b,Syk,Nr4a1,Met,Ptk2,Mdm2,Ier3,Psmb8,Psme2,Trib3,Cd80,Psma6,Rapgef2,Pde1b,Rasgrp1,Psme1,Prkar2b,Dusp5,Psmb6,Dusp6,Cdkn1a,Kitl,Pdgfb,Rictor,Ppp2r5a,Irs2,Ksr1,Il2rg,Pdgfrb,Cd86,Jak2,Map2k1 |
| 4.079e-04 | -7.80 | RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP | MSigDB lists | RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP | 71 | 15 | 15632 | 1249 |
Dusp4,Slc7a5,Peli1,Swap70,Gpr18,S100a8,Ezr,Birc3,Notch2,Map3k8,Ch25h,Max,Cd55,Il13ra1,Dusp5 |
| 4.109e-04 | -7.80 | Metabolism of polyamines | REACTOME pathways | R-MMU-351202 | 79 | 17 | 8608 | 757 |
Srm,Nqo1,Arg2,Odc1,Psmb9,Psme1,Psmb6,Smox,Psmb10,Sat1,Ass1,Psmb8,Psmd10,Psme2b,Psme2,Psma6,Nmral1 |
| 4.109e-04 | -7.80 | GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN | 178 | 28 | 15632 | 1249 |
Fam111a,Casp7,Mtdh,Kpna3,Scyl2,Smc5,Glrx,Ccl4,Tnfsf10,Irf8,Cenpj,Med21,Tnfrsf1b,Ccne1,Tshz1,Sirt1,Ube2l6,Sap30,Arl5b,Ccnd2,Rars,Mxd1,Sgcb,Rhof,Eno1,Rbbp8,Mlkl,Carhsp1 |
| 4.109e-04 | -7.80 | GSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_UP | MSigDB lists | GSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_UP | 178 | 28 | 15632 | 1249 |
Cd302,Tiparp,Slfn8,Nr3c1,Lztfl1,Zfp281,Ppm1l,Sell,Sgk3,Enpp4,Klf7,Mcmbp,Irak3,Pde4b,Card6,Dcun1d3,Cnn3,Bcl9,Ampd3,Usp12,Larp1,Ptk2,Filip1l,Dyrk2,Mppe1,Spata5l1,Clcf1,Slfn9 |
| 4.109e-04 | -7.80 | GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP | MSigDB lists | GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP | 178 | 28 | 15632 | 1249 |
Palld,Rnf139,Slco3a1,Slamf7,Slc16a1,Klf7,Aoah,Itpr1,Rgs14,Rab11fip1,Abcb1a,Gclm,Ifrd1,Dck,Dram1,Il12b,Map3k8,Cacnb3,Tgfbi,Cxcl1,Glrx,Htr2b,Snn,Txn1,Tor3a,Alas1,Bcorl1,Jag1 |
| 4.109e-04 | -7.80 | GSE30083_SP1_VS_SP3_THYMOCYTE_UP | MSigDB lists | GSE30083_SP1_VS_SP3_THYMOCYTE_UP | 178 | 28 | 15632 | 1249 |
Slc37a3,Gca,Trib1,Dram1,Dusp5,Mmp9,Nfkbid,Hivep3,Mmd,Stx11,Ext1,Cnn3,Nfkbib,Lad1,Junb,Ccr1,Hsd17b12,Ccl5,Spred1,Etv5,Tmem176b,Prdx5,Ccdc86,Ubtd2,Tcf4,Dusp1,Armcx6,Hivep2 |
| 4.109e-04 | -7.80 | GSE27786_LSK_VS_NKCELL_DN | MSigDB lists | GSE27786_LSK_VS_NKCELL_DN | 178 | 28 | 15632 | 1249 |
Slfn9,Jak2,Zhx2,Slc37a3,Rtn1,Ptgir,Cpeb4,Mthfd2,Plekha2,Zbp1,Ccdc88b,Pde3b,Olr1,Chmp4b,Tlr6,St3gal6,Ddx58,Stard5,Slfn8,Gpr68,Rsad2,Ap3b1,Errfi1,Abcc5,Klf3,Nfkbia,Axl,Nlrc5 |
| 4.109e-04 | -7.80 | GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_DN | MSigDB lists | GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_DN | 178 | 28 | 15632 | 1249 |
Rhoq,Bcl2a1d,C1ra,Gsr,Cenpe,Klf6,Bcl2a1b,Plekhf2,Casp1,Mdfic,Prdm1,Itga4,Tab2,Hif1a,St3gal6,Btg2,Mmd,Rabgef1,Actb,Dek,Bcl2a1a,Adam19,Pgk1,Crkl,Ptger4,Aida,4930453N24Rik,Ier3 |
| 4.109e-04 | -7.80 | GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_UP | MSigDB lists | GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_UP | 178 | 28 | 15632 | 1249 |
Lmo4,Btg2,Hivep3,Parp3,Endod1,Rcsd1,Adam19,Cdkn1a,Snn,Trem1,Cenpe,Tpst1,Gpsm2,Gpr18,Acpp,Lrch1,Slc15a3,Pnp2,Ctsc,Aldh1b1,Pttg1,Slc16a1,Slamf7,Sdc4,Tnfaip3,Rab3ip,Hvcn1,Cd38 |
| 4.110e-04 | -7.80 | LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP | MSigDB lists | LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP | 102 | 19 | 15632 | 1249 |
Inhba,Jag1,Gadd45g,Pla2g4a,Pdgfb,Mmp14,Tspan3,Serpine1,Zyx,Dusp1,Junb,Ass1,Il15ra,Htr2b,Ahr,Actb,Gpc1,Ptgs2,Tmod3 |
| 4.110e-04 | -7.80 | GO_LYMPHOCYTE_MEDIATED_IMMUNITY | MSigDB lists | GO_LYMPHOCYTE_MEDIATED_IMMUNITY | 102 | 19 | 15632 | 1249 |
Fas,Cd55,H2-Ab1,C3,Cd74,Icam1,Il4ra,Prdx1,Batf,Slamf7,H2-Eb1,Swap70,Irf7,C1rl,Ctsc,Dennd1b,Jag1,C1ra,Pou2f2 |
| 4.132e-04 | -7.79 | cell adhesion molecule binding | molecular function | GO:0050839 | 235 | 31 | 20217 | 1400 |
Cdk5r1,Itga5,Itgal,Ptk2,Il1b,Nectin4,Tgfbi,Pvr,Mmp14,Nlgn2,Cx3cl1,Thbs1,Nos2,Itgav,Plpp3,Src,Icam1,Itga4,Nectin2,Pkp4,Itgb8,Syk,Kdr,Caml,Lyn,Ezr,S1pr2,Sell,Isg15,Ptpn2,Vcam1 |
| 4.155e-04 | -7.79 | GSE21033_1H_VS_24H_POLYIC_STIM_DC_UP | MSigDB lists | GSE21033_1H_VS_24H_POLYIC_STIM_DC_UP | 152 | 25 | 15632 | 1249 |
Itgav,Aftph,Dusp4,Il18bp,Nfkbie,Tlk2,Socs1,Gbp3,Pfkfb3,Mapkbp1,Myo10,Zc3h12c,Egln3,Hivep3,Dusp5,Smc5,Atp10a,Arl5c,Map3k8,Usp42,Parp11,Ralgds,Gfi1,Sec24b,Dusp16 |
| 4.155e-04 | -7.79 | GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 152 | 25 | 15632 | 1249 |
Ddx60,Psme1,Plk3,Il1a,Tulp3,Ehd1,Mrpl52,Swap70,Irf4,Gpr84,Nqo1,Larp1,Cacnb3,Gfpt1,Pfkl,Esd,Nlgn2,Trafd1,Rel,Sco1,Med21,Csf1,Rab10,Rilpl1,Hat1 |
| 4.167e-04 | -7.78 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_DN | 187 | 29 | 15632 | 1249 |
Rhou,Dcp1a,Procr,Inpp5b,Plk2,Sema3c,Tuba4a,S100a8,Nampt,Pfkl,Tnip1,Ralgds,Il1rn,Ldha,Hp,Glipr2,Tcf4,Csf3r,Spic,Mrpl52,Ezr,Batf,Il4ra,Arg2,Jmjd6,Tpi1,Mcoln2,Nek6,Ier2 |
| 4.167e-04 | -7.78 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_UP | 187 | 29 | 15632 | 1249 |
Dnaja2,Trib3,Dnajb4,St7,Adrb2,Kitl,Ppfibp2,Wdr43,Brwd3,Tmeff1,Fabp7,Tulp3,Trim13,Slc30a1,Papss2,Jmjd6,Slc25a25,Tnf,Stat5a,Spsb1,Agrn,N4bp1,Spryd7,Slc7a11,Traf2,Hspa1a,Slc39a4,Nqo1,Stk40 |
| 4.224e-04 | -7.77 | negative regulation of production of molecular mediator of immune response | biological process | GO:0002701 | 35 | 9 | 20694 | 1406 |
Irak3,Bcl6,Angpt1,Ifnb1,Il10,Parp3,Fcgr2b,Hmox1,Tnf |
| 4.224e-04 | -7.77 | negative regulation of fibroblast proliferation | biological process | GO:0048147 | 35 | 9 | 20694 | 1406 |
Fbxo4,Mmp9,Myc,Nupr1,Parp10,Sod2,Morc3,Dach1,Pmaip1 |
| 4.224e-04 | -7.77 | regulation of syncytium formation by plasma membrane fusion | biological process | GO:0060142 | 35 | 9 | 20694 | 1406 |
Stat1,Cxcl10,Ccl8,Cxcl9,Gdf15,Tnfsf14,Il4ra,Cflar,Ehd1 |
| 4.224e-04 | -7.77 | positive regulation of pri-miRNA transcription by RNA polymerase II | biological process | GO:1902895 | 35 | 9 | 20694 | 1406 |
Pdgfb,Nr3c1,Stat3,Hif1a,Jun,Nfkb1,Fos,Il10,Bmp2 |
| 4.248e-04 | -7.76 | Central carbon metabolism in cancer | KEGG pathways | ko05230 | 64 | 15 | 7931 | 713 |
Pdgfrb,Slc7a5,Hk1,Hif1a,Pik3cd,Map2k1,Myc,Met,Hk3,Pfkl,Slc16a3,Ldha,Hk2,Akt3,Slc2a1 |
| 4.248e-04 | -7.76 | Central carbon metabolism in cancer | KEGG pathways | mmu05230 | 64 | 15 | 7931 | 713 |
Slc2a1,Ldha,Hk2,Akt3,Slc7a5,Hif1a,Hk1,Met,Hk3,Pfkl,Slc16a3,Pik3cd,Myc,Map2k1,Pdgfrb |
| 4.282e-04 | -7.76 | blood coagulation | biological process | GO:0007596 | 110 | 18 | 20694 | 1406 |
Papss2,Slc7a11,P2ry12,Ap3b1,Cx3cl1,Ubash3b,Stxbp3,Stxbp1,Lnpk,C3,Axl,F10,Enpp4,Ptprj,Evl,Pf4,Procr,Plek |
| 4.282e-04 | -7.76 | coagulation | biological process | GO:0050817 | 110 | 18 | 20694 | 1406 |
Procr,Plek,Evl,Pf4,Ptprj,Enpp4,F10,Axl,C3,Stxbp3,Lnpk,Stxbp1,Ubash3b,Ap3b1,Cx3cl1,P2ry12,Slc7a11,Papss2 |
| 4.306e-04 | -7.75 | regulation of cytokine secretion involved in immune response | biological process | GO:0002739 | 16 | 6 | 20694 | 1406 |
Angpt1,Tnfrsf1b,Il10,Tnfrsf14,Hk1,Tnf |
| 4.306e-04 | -7.75 | detection of other organism | biological process | GO:0098543 | 16 | 6 | 20694 | 1406 |
Nod1,Nod2,Tlr6,Tlr2,Tlr1,Nlrc4 |
| 4.306e-04 | -7.75 | detection of bacterium | biological process | GO:0016045 | 16 | 6 | 20694 | 1406 |
Tlr6,Tlr2,Nlrc4,Tlr1,Nod1,Nod2 |
| 4.309e-04 | -7.75 | MTOR_UP.V1_UP | MSigDB lists | MTOR_UP.V1_UP | 161 | 26 | 15632 | 1249 |
Psat1,Ifit1bl2,Ccl5,Gch1,Hivep3,Il18rap,Eef1e1,Oas2,Atxn7l1,Adora2b,Ak4,Mcm6,Hmgcs1,Ifi35,Hmox1,Idi1,Ldlr,Plat,Slc2a1,Ifit1bl1,Ifit2,Ccdc86,Usp18,Atf3,Kif9,Lipg |
| 4.309e-04 | -7.75 | GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_UP | 161 | 26 | 15632 | 1249 |
Hsd17b12,Mthfd1l,Tnfrsf1b,Rrs1,Ppp4r2,Stat4,Stx6,Stx11,Naa25,Hmgcs1,Phf6,Rcn1,Snapc1,Irak2,Nfil3,Hsph1,Eno1,Kdm5b,S1pr2,Mcoln2,Il4ra,Extl2,Chmp4b,Tnfaip3,Relb,Slc28a2 |
| 4.309e-04 | -7.75 | WNT_UP.V1_DN | MSigDB lists | WNT_UP.V1_DN | 161 | 26 | 15632 | 1249 |
Dio2,Cmpk2,Pcdh7,Adam19,Kitl,Kcna3,Acvr1b,Ptgs2,Clec4d,Pim2,Oas1g,Oas1a,Il12rb1,Met,Irf7,Dnase1l3,F10,Tal2,Tnfrsf8,Adar,Usp18,Gbp3,Isg15,Ifih1,Tlr6,Eif2ak2 |
| 4.331e-04 | -7.74 | LEE_LIVER_CANCER_E2F1_UP | MSigDB lists | LEE_LIVER_CANCER_E2F1_UP | 64 | 14 | 15632 | 1249 |
Tmem176b,Usp18,Cd74,Cxcl10,Bcl2a1a,Plat,Ifit2,Bcl2a1b,Lcn2,Casp4,Ets2,Ifi44,Plscr1,Bcl2a1d |
| 4.360e-04 | -7.74 | TYR_PHOSPHATASE_DUAL | prosite domains | PS50054 | 31 | 9 | 13278 | 1037 |
Dusp8,Dusp5,Dusp28,Dusp1,Dusp6,Dusp14,Dusp16,Dusp4,Dusp2 |
| 4.368e-04 | -7.74 | RUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP | MSigDB lists | RUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP | 19 | 7 | 15632 | 1249 |
Cp,Sod2,Stat1,Hp,Lipe,F11r,Tap2 |
| 4.368e-04 | -7.74 | GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP | MSigDB lists | GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP | 19 | 7 | 15632 | 1249 |
Cxcl1,Rgs1,Il1b,Cxcl2,Tnfsf4,Sod2,Jun |
| 4.368e-04 | -7.74 | BIOCARTA_ATM_PATHWAY | MSigDB lists | BIOCARTA_ATM_PATHWAY | 19 | 7 | 15632 | 1249 |
Mdm2,Cdkn1a,Nfkbia,Atm,Nfkb1,Jun,Rbbp8 |
| 4.371e-04 | -7.74 | IRF | smart domains | SM00348 | 9 | 5 | 9567 | 823 |
Irf7,Irf2,Irf1,Irf8,Irf4 |
| 4.384e-04 | -7.73 | KIM_MYC_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYC_AMPLIFICATION_TARGETS_DN | 79 | 16 | 15632 | 1249 |
Plekha2,Plekhg1,Etv6,Cebpd,Optn,Rnf19a,Ifih1,Ttc39b,Fam111a,F11r,Ddx58,Atp2b4,Kitl,Gca,Tmem67,Cflar |
| 4.389e-04 | -7.73 | Signalling by NGF | REACTOME pathways | R-MMU-166520 | 407 | 56 | 8608 | 757 |
Psme2,Trib3,Psma6,Cd80,Mdm2,Met,Ptk2,Ripk2,Psmb8,Ier3,Dusp4,Psmb6,Dusp6,Prkar2b,Psme1,Dusp5,Rasgrp1,Bcl2l11,Rapgef2,Pde1b,Irs2,Ppp2r5a,Rictor,Pdgfb,Casp2,Cdkn1a,Kitl,Jak2,Map2k1,Cd86,Pdgfrb,Ksr1,Abr,Nfkbia,Il2rg,Myd88,Casp3,Psmd10,Phlpp1,Psmb10,Crkl,Psmb9,Sqstm1,Pik3cd,Mapkapk2,Phlpp2,Src,Angpt1,Psme2b,Ralgds,Nfkb1,Spred1,Nr4a1,Ppp2r1b,Prkce,Arhgef3 |
| 4.403e-04 | -7.73 | GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN | 144 | 24 | 15632 | 1249 |
Fgr,Spata13,Slamf7,Il15,Dnase1l3,Crim1,Casp1,Cx3cr1,Traf2,Itpr1,Spry2,Ccr3,Lztfl1,Dgkh,Ptger4,Cd82,Gfpt1,Cmklr1,Notch2,Glrx,Il10,Ksr1,Il18rap,Smpdl3b |
| 4.406e-04 | -7.73 | GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BINDING | MSigDB lists | GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BINDING | 14 | 6 | 15632 | 1249 |
Pdgfc,Lyn,Pdgfrb,Ptprj,Pdgfb,Itga5 |
| 4.406e-04 | -7.73 | GO_INTERLEUKIN_1_PRODUCTION | MSigDB lists | GO_INTERLEUKIN_1_PRODUCTION | 14 | 6 | 15632 | 1249 |
Il1b,Nlrp3,Nlrc4,Casp1,Tlr6,Aim2 |
| 4.406e-04 | -7.73 | GO_CELLULAR_RESPONSE_TO_INTERFERON_BETA | MSigDB lists | GO_CELLULAR_RESPONSE_TO_INTERFERON_BETA | 14 | 6 | 15632 | 1249 |
Irf1,Ifnb1,Tlr3,Aim2,Pnpt1,Stat1 |
| 4.406e-04 | -7.73 | RUAN_RESPONSE_TO_TNF_UP | MSigDB lists | RUAN_RESPONSE_TO_TNF_UP | 14 | 6 | 15632 | 1249 |
Cp,Stat1,Sod2,Hp,Tap2,F11r |
| 4.406e-04 | -7.73 | GO_REGULATION_BY_VIRUS_OF_VIRAL_PROTEIN_LEVELS_IN_HOST_CELL | MSigDB lists | GO_REGULATION_BY_VIRUS_OF_VIRAL_PROTEIN_LEVELS_IN_HOST_CELL | 14 | 6 | 15632 | 1249 |
Ifit1bl1,Ifit1bl2,Stat1,Tap2,Stau1,Tap1 |
| 4.406e-04 | -7.73 | BIOCARTA_CD40_PATHWAY | MSigDB lists | BIOCARTA_CD40_PATHWAY | 14 | 6 | 15632 | 1249 |
Tnfaip3,Nfkbia,Dusp1,Nfkb1,Ikbkg,Cd40 |
| 4.406e-04 | -7.73 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | MSigDB lists | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | 14 | 6 | 15632 | 1249 |
Ddx58,Irf7,Rnf135,Ifih1,Ifnb1,Ikbke |
| 4.408e-04 | -7.73 | GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 356 | 47 | 15632 | 1249 |
Rnf34,Crim1,Rhoh,F11r,Rffl,Mdm2,Prdx5,Ifi213,Src,Tnf,Cst7,Timp1,Ifi205,Birc2,Ifi209,Thbs1,Serpinb2,Plaur,Serpinb9,Ifi208,Sh3bp4,Spint2,Ifit1bl2,Ppp1r15a,Serpine1,Spred1,Ifi207,Cdkn2d,Pttg1,Ifi214,Spry2,Il6,Ifit1bl1,Nlrc4,Tlr9,C3,Mmp9,Ifi204,Ifi211,Cnn3,Slpi,Sirt1,Ifi203,Birc3,Tnfsf14,Casp8,Mndal |
| 4.422e-04 | -7.72 | regulation of B cell mediated immunity | biological process | GO:0002712 | 58 | 12 | 20694 | 1406 |
Nod2,Tnf,Clcf1,Cd40,Parp3,C3,Cd55,Tnfsf4,Nectin2,Fcgr2b,Fcgr1,Bcl6 |
| 4.422e-04 | -7.72 | regulation of immunoglobulin mediated immune response | biological process | GO:0002889 | 58 | 12 | 20694 | 1406 |
Cd40,Clcf1,Tnf,Nod2,Fcgr1,Bcl6,Tnfsf4,Nectin2,Fcgr2b,C3,Cd55,Parp3 |
| 4.425e-04 | -7.72 | GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_DN | 170 | 27 | 15632 | 1249 |
Ppa1,Dusp5,Casp7,H2-Ab1,Xkr8,Ptafr,Mthfd2,Ak4,Tmem229b,Ldlr,Sp110,Mob3c,Mov10,St3gal5,Noc4l,Pdlim7,Trim21,Rapgef2,Stoml1,Bst1,Dtx3l,Etv5,Hvcn1,Slc25a37,Dse,Pnp2,Tbc1d1 |
| 4.425e-04 | -7.72 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP | 170 | 27 | 15632 | 1249 |
Plcl2,Fpr1,Mppe1,Phf11d,Dyrk2,Sema4c,Tlr3,Cd69,Rasgrp1,Rap1gap2,Ptch1,Phf11c,Slc28a2,Klf7,Phf11a,Arl4a,Nlrp3,Irs2,Plk3,Cebpd,Fchsd2,Jun,Arhgef3,Acpp,Fos,Dusp1,Phf11b |
| 4.425e-04 | -7.72 | GSE3982_EFF_MEMORY_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_EFF_MEMORY_VS_CENT_MEMORY_CD4_TCELL_UP | 170 | 27 | 15632 | 1249 |
Cx3cr1,Aoah,Parp8,4932438A13Rik,Ccnd1,Phactr4,Tnc,Klf8,Ccl22,Fgr,Ch25h,Enpp4,Extl2,Hopx,Lcn2,Tnfrsf1b,Rap1gap2,Syne2,Nrp2,Phyh,Azi2,Pkp4,Agpat4,Gfi1,Keap1,Chd9,Ldlr |
| 4.425e-04 | -7.72 | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | 170 | 27 | 15632 | 1249 |
Peli1,Taf4b,Ogfrl1,Pik3r5,Nfkbia,Tmem184b,Tcf4,Cd302,Mvp,Notch1,Csrnp1,Rhoh,Bcor,Nxf1,Cdk5r1,Dtx3l,Etv3,Hif1a,Ubash3b,Btg2,Reps1,Rictor,Rapgef2,Zfp324,Ccnj,Ptger4,Map3k8 |
| 4.435e-04 | -7.72 | Adipocytokine signaling pathway | KEGG pathways | ko04920 | 71 | 16 | 7931 | 713 |
Acsl1,Nfkbie,Nfkb1,Slc2a1,Tnfrsf1b,Acsl5,Akt3,Traf2,Irs2,Socs3,Nfkbia,Stat3,Jak2,Ikbkg,Nfkbib,Tnf |
| 4.435e-04 | -7.72 | Adipocytokine signaling pathway | KEGG pathways | mmu04920 | 71 | 16 | 7931 | 713 |
Akt3,Acsl5,Nfkbie,Tnfrsf1b,Slc2a1,Nfkb1,Acsl1,Tnf,Nfkbib,Stat3,Jak2,Ikbkg,Nfkbia,Irs2,Socs3,Traf2 |
| 4.437e-04 | -7.72 | Ser-Thr/Tyr_kinase_cat_dom | interpro domains | IPR001245 | 132 | 21 | 19984 | 1430 |
Pdgfrb,Src,Met,Ksr1,Syk,Flt1,Tyk2,Mlkl,Acvrl1,Kdr,Nek6,Ripk2,Ptk2,Jak2,Ripk3,Acvr1,Fgr,Igf1r,Lyn,Axl,Hck |
| 4.473e-04 | -7.71 | Glycolysis | REACTOME pathways | R-MMU-70171 | 28 | 9 | 8608 | 757 |
Hk2,Pfkl,Hk3,Eno2,Tpi1,Pgk1,Pfkfb3,Hk1,Eno1 |
| 4.485e-04 | -7.71 | GO_POSITIVE_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | MSigDB lists | GO_POSITIVE_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 57 | 13 | 15632 | 1249 |
Pdgfc,Angpt1,Jak2,Kdr,Hcls1,Fgr,Ptk2,Sirt1,Csf3,Pdgfb,Pdgfrb,Flt1,Ccl5 |
| 4.485e-04 | -7.71 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | MSigDB lists | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | 57 | 13 | 15632 | 1249 |
Uba7,Flnb,Ube2l6,Ifit1bl1,Ifit1bl2,Eif4g2,Eif2ak2,Isg15,Usp18,Ddx58,Stat1,Kpna3,Ube2e1 |
| 4.490e-04 | -7.71 | IKEDA_MIR1_TARGETS_UP | MSigDB lists | IKEDA_MIR1_TARGETS_UP | 50 | 12 | 15632 | 1249 |
Fndc3a,Spred1,Crim1,Rsbn1,Arf4,Gclc,Plk2,Cited2,Acvr1,Jag1,Edn1,Cnn3 |
| 4.490e-04 | -7.71 | GO_NEGATIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | 50 | 12 | 15632 | 1249 |
Tnip1,Lyn,Atf3,Lif,Errfi1,Spry2,Rgs14,Cav1,Ptpn2,Dusp1,Ezr,Dusp6 |
| 4.497e-04 | -7.71 | TOOKER_GEMCITABINE_RESISTANCE_DN | MSigDB lists | TOOKER_GEMCITABINE_RESISTANCE_DN | 119 | 21 | 15632 | 1249 |
Slc7a5,Triobp,Vcan,Slc39a14,Cox17,Sh3bp4,Cept1,Slc7a11,P4ha2,Ezr,Psat1,Plod2,Cacybp,Asns,Ahsa1,Clic4,Pdgfc,Malt1,Cd55,Papss2,Trib3 |
| 4.499e-04 | -7.71 | nucleobase-containing compound catabolic process | biological process | GO:0034655 | 230 | 30 | 20694 | 1406 |
Enpp4,Polr2g,Zfp36,Dcp1a,Zc3h12a,Dnase1l3,Oas2,Pde5a,Zhx2,Xrn1,Helz2,Tent2,Rnaset2a,Samhd1,Ago3,Smg7,Cnp,Isg20,Noct,Slfn8,Gtpbp2,Dcp2,Tut7,Mgat1,Pnpt1,Magohb,Apobec3,Tent4a,Atm,Upp1 |
| 4.508e-04 | -7.70 | GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_UP | MSigDB lists | GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_UP | 179 | 28 | 15632 | 1249 |
Clic4,Chd9,Nfkb2,Tlr2,Ell2,Pou2f2,Tdrd7,Rel,Plek,Myadm,Hvcn1,Relb,Irak3,Cutc,Nmral1,Icam1,Pikfyve,Gbp3,Magohb,Mapkapk2,Arhgap26,Nfkbie,Irgq,D1Ertd622e,Nat2,Cd40,Ehd1,Apobec3 |
| 4.532e-04 | -7.70 | regulation of lymphocyte chemotaxis | biological process | GO:1901623 | 22 | 7 | 20694 | 1406 |
Ccl5,Ccl12,Tnfsf14,Lgals9,Ccl4,Cxcl10,Cxcl14 |
| 4.532e-04 | -7.70 | detection of external biotic stimulus | biological process | GO:0098581 | 22 | 7 | 20694 | 1406 |
Nod1,Nod2,Tlr2,Tlr1,Tlr6,Itgav,Nlrc4 |
| 4.557e-04 | -7.69 | GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | MSigDB lists | GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 536 | 65 | 15632 | 1249 |
Acvr1b,Rcn1,Mafg,Sema4c,Socs3,Lhx2,Rpgrip1l,Il10,Sema3c,P2ry2,Lmo4,Casp8,Ptch1,Atm,Zeb1,Slc30a1,Fas,Angpt1,Sdc4,Hinfp,Adar,Spic,Bcl2l11,Sbds,Chst11,Ift57,Phactr4,Edn1,Mmp14,Sec24b,Keap1,Fzd5,Klf2,Hopx,Map2k1,Med21,Mthfd1l,Junb,Gja1,Fzd1,Maff,Vasp,Ppp2r3a,Ext1,Inpp5b,Pdgfb,Tulp3,Hif1a,Intu,Prdm1,Hhex,Lif,Apba1,Apaf1,Notch1,Pbx1,Bmp2,Mgat1,Eno1,Rbbp8,Plod3,Acvr1,Acvrl1,Fut8,Phgdh |
| 4.559e-04 | -7.69 | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_UP | MSigDB lists | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_UP | 188 | 29 | 15632 | 1249 |
Gbp7,Rnaset2a,Txn1,Hk2,Hap1,Oas1a,Ldha,Oas1g,Trafd1,Cdkn1a,Rnaset2b,Lacc1,Adam19,Bcl2a1a,Rbbp8,Bcl2a1b,Bcl2a1d,Mlkl,Optn,Casp3,Tnc,Isg15,Tpx2,Rab19,Pml,Tap1,Cd80,Adar,Cd83 |
| 4.559e-04 | -7.69 | GSE24142_DN2_VS_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_UP | 188 | 29 | 15632 | 1249 |
Il4ra,Lif,Itga4,Hhex,Cd34,Cd302,Cyfip1,Cst7,Map3k6,Cnn2,Ogfrl1,Rai14,Fcgr2b,Fut8,Clec4d,Ier3,Pim1,Cmpk2,Rgs1,Myadm,Dusp6,Ccl5,Tuba4a,Hsd17b12,Slc7a8,Car13,Pdlim7,Plscr1,Procr |
| 4.559e-04 | -7.69 | GSE7852_TREG_VS_TCONV_FAT_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_FAT_DN | 188 | 29 | 15632 | 1249 |
Sema4a,Phf6,Trib3,Cox18,Ptger4,Epsti1,Inpp1,Tnfsf14,Map4k4,Slc12a9,G3bp2,Phlpp2,Trim21,Rtp4,Jmjd6,St3gal6,Trim13,Atp11b,Rgs3,Gpc1,Nod1,Hspa1a,Cited2,Gpr18,Hivep2,Klf3,Arhgap26,Fchsd2,Irgm2 |
| 4.559e-04 | -7.69 | GSE27786_CD8_TCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NKTCELL_DN | 188 | 29 | 15632 | 1249 |
Hmga1,Aoah,Chst11,Rin2,Dock10,Prdx5,Phactr4,Fcgr2b,Carhsp1,Tab2,Itga4,Prdm1,Stxbp1,Cd38,Relb,Pbx1,Itgal,Gem,Tnfrsf1b,Inhba,Rap1gap2,Tdrd7,Atxn7l1,Plscr1,Fpr1,Gfi1,Nfil3,Tnfsf10,Cd82 |
| 4.573e-04 | -7.69 | SASSON_RESPONSE_TO_GONADOTROPHINS_UP | MSigDB lists | SASSON_RESPONSE_TO_GONADOTROPHINS_UP | 87 | 17 | 15632 | 1249 |
Col18a1,Cd55,Cdc42ep4,Jmjd6,Upp1,Prkx,Actb,Pgk1,Acp2,Tnfaip3,Stip1,Dusp1,P4ha2,Map2k1,Itpr1,Acpp,Hk2 |
| 4.573e-04 | -7.69 | WINTER_HYPOXIA_UP | MSigDB lists | WINTER_HYPOXIA_UP | 87 | 17 | 15632 | 1249 |
Ldha,Tpi1,Ak4,Adora2b,Pdzd11,Plau,Ldlr,Slc16a1,Igf2bp2,Rhoc,Pgk1,P4ha1,Vezt,Homer1,Slc2a1,Bnip3,Rnf24 |
| 4.598e-04 | -7.68 | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP | 153 | 25 | 15632 | 1249 |
Chd9,Rgs1,Klf7,Agpat4,Samhd1,Snn,Itga4,Mxd1,Socs3,Parp3,Ptgs2,Ubash3b,Kcna3,Irs2,Fam111a,Ddit4,St3gal5,Rapgef2,Maff,Rap1gap2,Parp8,Dusp1,Pik3r5,Cited2,Jun |
| 4.598e-04 | -7.68 | GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_UP | MSigDB lists | GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_UP | 153 | 25 | 15632 | 1249 |
Arl4a,Rhoh,Egr1,Pgs1,Ier2,Gng11,Traf5,Bcl6,Dse,Slc25a37,Lipe,Il18bp,Dusp2,Rab11fip1,Rai14,Stat3,Fcho2,Dyrk2,Traf3ip2,Pmepa1,Tcea1,Tshz1,Pdk3,Casp2,Btg2 |
| 4.601e-04 | -7.68 | BRUINS_UVC_RESPONSE_EARLY_LATE | MSigDB lists | BRUINS_UVC_RESPONSE_EARLY_LATE | 280 | 39 | 15632 | 1249 |
Acvr1,Ifrd1,Cish,Dennd1b,Spry2,Irgm2,Ptpn2,P2ry12,Traf2,Ddhd1,Dusp14,Etv5,Rab3ip,Rnd3,Rras2,Dtwd1,Zfp281,Pgm1,Tulp3,Pou2f2,Trim26,Rilpl1,Fubp1,Ppp1r15b,Ahrr,Snx10,Cdyl,Gfi1,Dusp28,Sec24b,Dusp16,Igf1r,Mitd1,Plat,Frmd4a,Filip1l,Dyrk2,Socs3,Kpna3 |
| 4.616e-04 | -7.68 | mouse chr19|19 C1 | chromosome location | mouse chr19|19 C1 | 56 | 11 | 24173 | 1464 |
Ch25h,Asah2,Insl6,Ifit2,Ifit1,Rcl1,Ric1,Ifit3,Cd274,Ifit3b,Ifit1bl2 |
| 4.627e-04 | -7.68 | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 1043 | 113 | 15632 | 1249 |
Bambi,Tnfsf10,Plaur,Scyl2,Smc5,Prdm9,Ptprj,Scn1b,Pdgfb,Hap1,Csf3,Jarid2,Bmp2,Hck,Daxx,Notch1,Pml,Lif,Sphk1,Icam1,Il1a,Hif1a,Rhoq,Lrp4,Axl,Src,Ehd1,Swap70,Kdr,Hcls1,Nlgn2,Stard7,Nox1,Adrb2,Sirt1,Rnf31,P2ry2,Tnfsf14,Irf8,Cdc42ep2,Angpt1,Mark2,Lrp8,Tlr6,Abr,Il4ra,Phip,Prkce,Edn1,Triobp,Agrn,Bcl2l11,Flrt3,Ccl12,Ezr,Jun,Cyfip1,Gcnt2,Il1b,Cdc42ep4,Spire1,Piezo1,Vasp,Rapgef2,Gdf15,Myadm,Plek,Serpine1,Pdgfrb,Map2k1,Fzd5,Flrt2,Cd14,Plagl2,Aim2,Micall2,Rab21,Sele,Mecp2,Glipr2,Phldb1,Ddhd1,Tnf,Bcl6,Fscn1,Whamm,Fam162a,Mmp9,C3,Rac3,Lyn,Lpar1,Rhou,Rictor,Jdp2,Atm,Casp8,Cav1,Sdc4,Fas,Nck1,Evl,Mpp7,Mul1,Cdk5r1,Kat2b,Sdc1,Stap1,Bnip3,Pla2g4a,Scarf1,Itgav,Syk |
| 4.632e-04 | -7.68 | Neutrophil degranulation | REACTOME pathways | R-MMU-6798695 | 557 | 72 | 8608 | 757 |
Rnaset2b,Lcn2,Ptafr,Itgal,Ctsc,Tlr2,Atp11a,H2-Q6,Serpinb6b,Pgm1,H2-T10,Serpina3f,C3,Gpr84,Atp11b,Sell,Slpi,Fpr2,H2-Q7,S100a8,Cxcl2,Gsdmd,Ampd3,Ubr4,Tarm1,Tnfrsf1b,Bst1,Pfkl,Mvp,Rnaset2a,Itgav,Mmp9,Cnn2,Olr1,Plac8,Dync1h1,Plau,Acpp,Cd14,Hp,H2-M2,Hspa1b,H2-Q4,Hvcn1,Mmp25,H2-T24,Hk3,Fgr,Fcgr4,Cd55,Apaf1,Clec5a,Pnp2,Cyfip1,Rap2c,Armc8,Rab10,Cxcl3,Fgl2,Dbnl,Rhof,Gca,Fpr1,Nfkb1,Cxcl1,Enpp4,Plaur,Atp6v1d,H2-T22,Clec4d,Ptprj,Fcgr2b |
| 4.640e-04 | -7.68 | GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP | MSigDB lists | GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP | 136 | 23 | 15632 | 1249 |
Plcl2,Slfn5,Rab3ip,Filip1l,Dyrk2,Slc30a4,Spata5l1,Pigv,Rnf145,Etv3,Rffl,Rab9,Cnn3,Gpr132,Acvrl1,Rnf19a,Treml2,Ube2e2,Kremen1,Pik3r5,Map4k4,Ets2,Gpr18 |
| 4.670e-04 | -7.67 | SESTO_RESPONSE_TO_UV_C0 | MSigDB lists | SESTO_RESPONSE_TO_UV_C0 | 103 | 19 | 15632 | 1249 |
Trim26,Rab21,Caml,Pnp2,Zfp36,Hsph1,Eif4g2,Nfkbia,Gdf15,Sqstm1,Brd2,Dnaja1,Cited2,Dr1,Il1rn,Bambi,Tap1,Hmox1,Prnp |
| 4.687e-04 | -7.67 | CD40 receptor complex | cellular component | GO:0035631 | 11 | 5 | 20747 | 1409 |
Rnf31,Traf2,Traf5,Cd40,Birc2 |
| 4.696e-04 | -7.66 | detection of molecule of bacterial origin | biological process | GO:0032490 | 11 | 5 | 20694 | 1406 |
Nod2,Tlr1,Tlr2,Itgav,Tlr6 |
| 4.696e-04 | -7.66 | negative regulation of neuroinflammatory response | biological process | GO:0150079 | 11 | 5 | 20694 | 1406 |
Cx3cl1,Cd200,Ldlr,Tnfrsf1b,Cst7 |
| 4.696e-04 | -7.66 | positive regulation of antigen processing and presentation | biological process | GO:0002579 | 11 | 5 | 20694 | 1406 |
H2-Ab1,Tap2,Cd74,Nod1,Nod2 |
| 4.696e-04 | -7.66 | regulation of toll-like receptor 2 signaling pathway | biological process | GO:0034135 | 11 | 5 | 20694 | 1406 |
Tlr1,Tlr6,Acod1,Nod2,Lyn |
| 4.696e-04 | -7.66 | peptidyl-serine dephosphorylation | biological process | GO:0070262 | 11 | 5 | 20694 | 1406 |
Nck1,Ppp2r2a,Dusp1,Ppp1r15b,Ppp1r15a |
| 4.696e-04 | -7.66 | positive regulation of chemokine biosynthetic process | biological process | GO:0045080 | 11 | 5 | 20694 | 1406 |
Egr1,Tnf,Il1b,Myd88,Tlr3 |
| 4.696e-04 | -7.66 | positive regulation of receptor biosynthetic process | biological process | GO:0010870 | 11 | 5 | 20694 | 1406 |
Nr1h3,Hif1a,Jak2,Edn1,Hdac1 |
| 4.696e-04 | -7.66 | positive regulation of chemokine (C-X-C motif) ligand 2 production | biological process | GO:2000343 | 11 | 5 | 20694 | 1406 |
Mcoln2,Hdac1,Cd74,Tnf,Ccl5 |
| 4.696e-04 | -7.66 | MyD88-independent toll-like receptor signaling pathway | biological process | GO:0002756 | 11 | 5 | 20694 | 1406 |
Tlr6,Tnip3,Prkce,Cd300lf,Tlr3 |
| 4.748e-04 | -7.65 | cellular response to antibiotic | biological process | GO:0071236 | 169 | 24 | 20694 | 1406 |
Bnip3,Mdm2,Sirt1,Pdgfrb,Zc3h12a,Nqo1,Axl,Kdm6b,Larp1,Sphk1,Tnfaip3,Prkce,Ripk3,Ahr,Egr1,Tlr9,Timeless,Src,Lcn2,Pla2g4a,Pdgfb,Il6,Daxx,Ccl7 |
| 4.751e-04 | -7.65 | RLR_CTR | prosite domains | PS51789 | 3 | 3 | 13278 | 1037 |
Ifih1,Ddx58,Dhx58 |
| 4.751e-04 | -7.65 | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_UP | 162 | 26 | 15632 | 1249 |
Malt1,Evl,Cd74,Cd83,Rras2,Traf5,Mdfic,Ezr,Plac8,Itpr1,Gpr18,Jun,Tcf4,Irf4,Mdn1,Stap1,H2-Ab1,Cd200,Odc1,Serpinb9,Arid5b,Esd,Irf8,Timeless,Phlpp2,Cd69 |
| 4.751e-04 | -7.65 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN | 162 | 26 | 15632 | 1249 |
Slc2a6,H2-Aa,Irf8,Cd86,Clic4,Orai2,H2-Ab1,Map3k8,Lyn,Stap1,Fchsd2,Rhoq,Fcgr2b,Tagln,Syk,Rhbdf2,Tcf4,Cd40,Swap70,Tspan3,Hck,Hhex,Fgr,Cd180,Cd74,Kmo |
| 4.751e-04 | -7.65 | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | 162 | 26 | 15632 | 1249 |
Acvr1,Mafk,Spry2,Edn1,Ppp2r5a,Egr2,Usp53,Dusp14,Ubash3b,Upp1,St3gal6,Atf3,Rnf19a,Wdfy1,Csf1,Tnfsf15,Tnfsf14,Atp6v1d,Serpine1,Gem,Ccr1,Rabgef1,Snapc1,Zcchc2,Rgs1,Trib1 |
| 4.751e-04 | -7.65 | PENG_GLUCOSE_DEPRIVATION_DN | MSigDB lists | PENG_GLUCOSE_DEPRIVATION_DN | 162 | 26 | 15632 | 1249 |
Fubp1,Mndal,Cd86,Ifi208,Ifi211,Ifi203,Usp12,Uchl1,Smc5,Ifi204,Asf1a,Dek,Arf4,Pgk1,Ifi213,Ehd1,Ifi205,Ifi209,Dnaja1,Tspan3,Rab9,Ppp2r5a,Ifi214,Sla,Traf5,Ifi207 |
| 4.751e-04 | -7.65 | GSE6259_CD4_TCELL_VS_CD8_TCELL_UP | MSigDB lists | GSE6259_CD4_TCELL_VS_CD8_TCELL_UP | 162 | 26 | 15632 | 1249 |
Egln3,Csf1,Fabp7,Pdlim7,Layn,Ltbp2,Dcbld2,Plaur,Fam162a,Cacnb3,Gpd2,Rtn1,Micall2,Mdn1,Il6,Timp1,Cenpe,Tagln,Atp2b4,Tsku,Bmp2,Il1a,Ccl22,Rnd1,Ch25h,Lrp8 |
| 4.763e-04 | -7.65 | C-type lectin receptors (CLRs) | REACTOME pathways | R-MMU-5621481 | 117 | 22 | 8608 | 757 |
Ikbkg,Casp8,Psmb10,Nfkb1,Psmb8,Psme2b,Psmd10,Clec4n,Malt1,Relb,Lyn,Tab2,Src,Psma6,Psme2,Nfkbia,Psmb9,Nfkb2,Il1b,Psme1,Syk,Psmb6 |
| 4.809e-04 | -7.64 | nuclear membrane | cellular component | GO:0031965 | 231 | 30 | 20747 | 1409 |
Ankrd17,Itpr1,Rap1gap2,Dusp2,Ccnd2,Phf11d,Phf11c,Ednrb,Osbpl3,Gch1,Dnajb2,Dtx2,Phlpp1,Sirt1,Syne2,Ptger4,Phf11b,Sh3bgrl2,Dpy19l1,Tor1aip1,Smox,Phf11a,Pml,Prnp,Slc30a1,Nr4a1,Trib3,Prpf38a,Slc16a3,Tent4a |
| 4.813e-04 | -7.64 | regulation of proteolysis involved in cellular protein catabolic process | biological process | GO:1903050 | 210 | 28 | 20694 | 1406 |
Rnf14,Plk3,Ankib1,Usp25,Hspa1a,Psme2,Pml,Ctsc,Sco1,Tlk2,Caml,Plk2,Rnf19a,N4bp1,Hspa1b,Trib1,Dnajb2,Nupr1,Psmd10,Tmem67,Trib3,Rnf19b,Cop1,Ptk2,Gclc,Mdm2,Rnf139,Psme1 |
| 4.817e-04 | -7.64 | regulation of neuron differentiation | biological process | GO:0045664 | 774 | 77 | 20694 | 1406 |
Sipa1l1,Sema4c,Nlgn2,Mycl,D16Ertd472e,Mosmo,Ifrd1,Igf1r,Lrp8,Ccl5,Zhx2,Kat2b,Ednrb,Bcl6,Rac3,Zeb1,Prag1,Agrn,Mark2,Dync1i2,Ptk2,Kif3c,Mecp2,Mov10,Zswim4,Cx3cl1,P2ry2,Tcf4,Ehd1,Fzd1,Met,Nck1,Ust,Sdc2,Etv5,Katna1,Rab21,Itpr1,Sphk1,Dbnl,Rap1gap2,Crkl,Pbx1,Cdk5r1,Lyn,Cav1,Kremen1,Sirt1,Mdm2,Il1b,Scarf1,Notch1,Il15ra,Gfi1,Casz1,Cyfip1,Scn1b,Il6,Lif,Kdm4a,Jag1,Mul1,Mmd,Lpar1,Lrp4,Cflar,Rapgef2,Plk2,Map4k4,Sema3c,Cd38,Nr3c1,Eif4g2,Bmp2,Map2k1,Hap1,Sema4a |
| 4.822e-04 | -7.64 | CEBPB_02 | MSigDB lists | CEBPB_02 | 234 | 34 | 15632 | 1249 |
Map4k4,Asah2,Lmo4,Pdgfb,Slc25a12,Ube2e2,Kpna3,Trib1,Ttc39b,Adrb2,Pcdh7,H3f3b,Nfil3,Dusp1,Nfkbia,Phldb1,Slc7a11,Bcl6,Pla2g4a,Kcnj2,Stat3,Cp,Rbpms,Vcan,Nfkbiz,Nek6,Ccnd2,Nlrp3,Il27,Pde3b,Gys1,Rab3ip,Spred1,Angpt1 |
| 4.822e-04 | -7.64 | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN | MSigDB lists | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN | 234 | 34 | 15632 | 1249 |
Spire1,Ier3,Trib1,Rcn1,Dusp5,C3,Acp2,Cflar,C1rl,Fosb,Irf8,Ppp1r15a,Dcun1d3,Rgl1,Spint2,Slc7a5,Piezo1,Ociad1,Prnp,Csrnp1,Egr1,Myo10,Dnase1l3,Lipg,Ets2,Fos,B4galt4,Slc25a37,Axl,Ezr,Gadd45g,Ccnd1,Setdb2,Phgdh |
| 4.823e-04 | -7.64 | CROONQUIST_NRAS_SIGNALING_UP | MSigDB lists | CROONQUIST_NRAS_SIGNALING_UP | 37 | 10 | 15632 | 1249 |
Snn,Ccl4,Msr1,Cd86,Dusp6,Ccl5,Malt1,Ifit1bl2,Ifit1bl1,Cx3cr1 |
| 4.823e-04 | -7.64 | GO_ATP_GENERATION_FROM_ADP | MSigDB lists | GO_ATP_GENERATION_FROM_ADP | 37 | 10 | 15632 | 1249 |
Eno2,Tpi1,Ldha,Hk1,Eno1,Pfkfb3,Pfkl,Hk3,Hk2,Pgk1 |
| 4.829e-04 | -7.64 | positive regulation of nervous system development | biological process | GO:0051962 | 653 | 67 | 20694 | 1406 |
Sema4a,Adgrl2,Hap1,Map2k1,Bmp2,Eif4g2,Nr3c1,Rapgef2,Cflar,Lpar1,Mmd,Mul1,Lif,Kdm4a,Cyfip1,Il6,Scn1b,Hif1a,Fubp1,Rgs14,Notch1,Il1b,Scarf1,Sirt1,Tnfrsf1b,Lyn,Tlr2,Clcf1,Crkl,Sphk1,Dbnl,Flrt3,Itpr1,Rab21,Cx3cr1,Etv5,Nck1,Hdac1,Met,Ehd1,Fzd1,P2ry12,Tcf4,Tspo,P2ry2,Tnf,Cx3cl1,Vegfc,Mecp2,Kif3c,Kdr,Mark2,Ptk2,Cst7,Zeb1,Agrn,Bcl6,Myc,Flrt2,Kat2b,Lrp8,Ccl5,Csf1,Igf1r,Nlgn2,D16Ertd472e,Spen |
| 4.841e-04 | -7.63 | secretion by cell | biological process | GO:0032940 | 407 | 46 | 20694 | 1406 |
Nos2,Il6,Hap1,Stx11,Trem1,Plek,Hck,Lyn,Inhba,Tlr2,Nr4a3,Nlrc4,Lcp2,Rims3,Tlr6,Pdzd11,Itgav,Axl,Notch1,Nlrp3,Isg15,Pou2f2,Optn,Apba1,Rab11fip1,Aim2,Syk,Mcoln2,Mecp2,Stxbp1,Ccr1,Dio2,Rasgrp1,Milr1,Ppfia3,Nod2,Notch2,Rab10,Ccl5,Edn1,Stxbp3,Rnf19b,Tnfaip2,Il1rn,Traf3ip2,Svbp |
| 4.864e-04 | -7.63 | GSE27786_LIN_NEG_VS_BCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_BCELL_DN | 171 | 27 | 15632 | 1249 |
Bfar,Cd164,Pml,Gbp3,Trim12c,Ccnd2,Icam1,Phip,Stard5,Fcgr2b,Ikzf1,Phlpp1,Sqstm1,Psmb9,Dusp16,Mob3c,Parp3,Dtx2,Stat1,Rnf19b,Mtmr14,Tmem229b,Chic2,Syne2,Oas2,Usp12,G3bp2 |
| 4.864e-04 | -7.63 | GSE3982_MAST_CELL_VS_MAC_DN | MSigDB lists | GSE3982_MAST_CELL_VS_MAC_DN | 171 | 27 | 15632 | 1249 |
Ak4,Stat1,Il13ra1,Uchl1,Acp2,Clcn7,Tnfsf14,Adap2,Slc7a8,Usp12,Inhba,Hivep3,Ppp2r3a,Kmo,Hlx,Me1,Rbl1,Pilra,Cyfip1,Jun,Parp8,Optn,Psma6,Scarf1,Fchsd2,Rhoq,Rai14 |
| 4.864e-04 | -7.63 | GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_DN | MSigDB lists | GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_DN | 171 | 27 | 15632 | 1249 |
Rap2c,Kif3c,Clec4d,Grina,Ampd3,Slpi,Card6,Gna15,Cutc,Tspo,Myd88,Batf,Irak3,Zfp319,Pdgfc,Hk3,Klf7,Pgs1,Upp1,Gpr84,B3gnt5,Prdx5,Cst7,Plac8,P4ha2,Nlrc4,Timp1 |
| 4.884e-04 | -7.62 | positive regulation of carbohydrate metabolic process | biological process | GO:0045913 | 84 | 15 | 20694 | 1406 |
Ptger4,Pdgfb,Ptafr,Hif1a,Nfkb1,Irs2,Kat2b,Prkce,Htr2a,Myc,Src,Dyrk2,Sirt1,Ptpn2,Ranbp2 |
| 4.884e-04 | -7.62 | negative regulation of protein modification by small protein conjugation or removal | biological process | GO:1903321 | 84 | 15 | 20694 | 1406 |
Dtx3l,Svbp,N4bp1,Caml,Parp10,Isg15,Gclc,Trim21,Dnaja1,Gbp4,Prkce,Tspo,Tnfaip3,Cav1,Dnajb2 |
| 4.886e-04 | -7.62 | GSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_UP | MSigDB lists | GSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_UP | 145 | 24 | 15632 | 1249 |
Tnfsf10,Cldnd1,Zcchc2,Dek,Jak2,Tmem67,Elmod2,Agpat4,Smc5,Nsmaf,Irf1,Ccdc25,Cep350,Cenpj,Irf8,Cd274,Slc28a2,Ahr,Atp2b4,Xrn1,Nmral1,Mdm2,N4bp1,Itgav |
| 4.886e-04 | -7.62 | GSE40274_FOXP3_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 145 | 24 | 15632 | 1249 |
Pdss1,Egln3,Cd86,Osm,Zcchc2,Inpp1,Slc37a3,Tmem219,Tnfsf4,Cd55,Arl5c,Rcsd1,Parp14,Rab9,Phlpp1,Dusp4,Rapgef5,Ddhd1,Pnpt1,Slc30a4,Fas,Egr1,Mcoln2,Kat2b |
| 4.886e-04 | -7.62 | BROWNE_HCMV_INFECTION_14HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_14HR_UP | 145 | 24 | 15632 | 1249 |
Tfec,Ppp2r2a,Hmox1,Max,Syne2,Slc39a14,Eya4,Alas1,Slc7a5,Fzd5,Ccne1,Etv5,Gclc,Smg7,Hinfp,Jmjd6,Nxf1,Calcrl,Marcksl1,Cers6,Gclm,Fos,Abcc5,Morc3 |
| 4.920e-04 | -7.62 | positive regulation of B cell proliferation | biological process | GO:0030890 | 43 | 10 | 20694 | 1406 |
Cdkn1a,Cd74,Irs2,Clcf1,Bcl6,Cd38,Cd40,Tlr9,Peli1,Bst1 |
| 4.920e-04 | -7.62 | regulation of response to reactive oxygen species | biological process | GO:1901031 | 43 | 10 | 20694 | 1406 |
Il10,Sesn3,Gch1,Tnf,Txn1,Nr4a3,Glrx,Hsph1,Hk3,Met |
| 4.922e-04 | -7.62 | PH-like_dom_sf | interpro domains | IPR011993 | 398 | 47 | 19984 | 1430 |
Fam43a,Frmd6,Arhgef3,Ezr,Stap1,Phlpp2,Vasp,Irs2,Plekha5,Triobp,Spred1,Plek,Cyth3,Plekhn1,Plekha2,Psd,Gramd1a,Spred3,Ranbp2,Plcl2,Ptk2,Plekha4,Arhgap26,Plekhf2,Grk3,Carmil1,Asap3,Spata13,Frmd4a,Akt3,Adap2,Osbpl3,Apba1,Tbc1d1,Myo10,Plekhg1,Psd4,Pid1,Phlpp1,Dock10,Rgs3,Swap70,Dgkh,Dcp1a,Phldb1,Evl,Homer1 |
| 4.941e-04 | -7.61 | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN | MSigDB lists | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN | 180 | 28 | 15632 | 1249 |
Acp2,Adam19,Sema4c,Itga5,Car13,Cd69,Flnb,Rel,Casp8,Slc31a2,Pdk3,Ncoa7,Cd164,Sgcb,Fcgr1,Cd80,Sdc1,Icam1,Trim13,Il4ra,Mthfr,Mllt6,Ccl2,P2ry12,Dse,Zmynd15,Ifnar1,Phldb1 |
| 4.941e-04 | -7.61 | GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | MSigDB lists | GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | 180 | 28 | 15632 | 1249 |
Tyk2,Ddit4,Isg20,Cep350,Ppp1r15a,Junb,Lrrc8c,Ap3m2,Cflar,Rab20,Arid5b,Ttc39b,Gpr68,Tapbp,Dbnl,Abcb1a,Bcl6,Homer1,Traf2,Hsph1,Zc3hav1,Crim1,Rgs3,Ccdc88b,Batf,Herc3,Xrn1,Prdm1 |
| 4.941e-04 | -7.61 | GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | MSigDB lists | GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | 180 | 28 | 15632 | 1249 |
Uchl1,Fndc3a,Dnajb4,Tgfbi,Fam20c,Gng12,Esd,Pde4b,Gch1,Klf2,Plekha2,Lcn2,Ep400,Ampd3,Tmem176a,Tmem176b,Pml,Pbx1,Clcn5,Rab3ip,Tagln,Bcl2l11,Sat1,Rai14,Ccnd1,Ap3b1,Errfi1,Rin2 |
| 4.941e-04 | -7.61 | VEGF_A_UP.V1_UP | MSigDB lists | VEGF_A_UP.V1_UP | 180 | 28 | 15632 | 1249 |
Isg20,Ddit4,Ube2l6,Phlda1,Uba7,Adora2a,Eno2,Psmb8,Col11a2,Nfkb2,Lhx2,Ptprj,Fcgr2b,Dusp8,Optn,Nfkbie,Tagln,Ccl12,Traf5,Trp53i11,Sdc4,Htr2a,Rgs3,Relb,Atf3,Icam1,Irs2,Traf1 |
| 4.952e-04 | -7.61 | positive regulation of neurogenesis | biological process | GO:0050769 | 582 | 61 | 20694 | 1406 |
Zeb1,Mark2,Ptk2,Myc,Bcl6,Lrp8,Csf1,Ccl5,Kat2b,Nlgn2,D16Ertd472e,Spen,Igf1r,Etv5,Cx3cr1,Rab21,Met,Nck1,Hdac1,Tnf,Cx3cl1,P2ry2,Tcf4,P2ry12,Tspo,Ehd1,Fzd1,Kdr,Kif3c,Mecp2,Vegfc,Il1b,Scarf1,Notch1,Rgs14,Fubp1,Tnfrsf1b,Sirt1,Tlr2,Clcf1,Lyn,Itpr1,Sphk1,Dbnl,Crkl,Bmp2,Eif4g2,Map2k1,Hap1,Rapgef2,Nr3c1,Mul1,Mmd,Lpar1,Cflar,Hif1a,Cyfip1,Scn1b,Il6,Lif,Kdm4a |
| 4.984e-04 | -7.60 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP | 189 | 29 | 15632 | 1249 |
Swap70,Ttc39c,Cst7,Ccnd1,Pla2g4a,Fcgr2b,Pnp2,Rhoq,Cd180,Trim13,Slco3a1,P2ry14,Hhex,Nek6,Spred1,Slc28a2,Gys1,Gclc,Clec4e,Gna15,Pdgfrb,Birc3,Ube2e2,Procr,Plscr1,Tifa,Fam111a,Ttc39b,Nlgn2 |
| 4.984e-04 | -7.60 | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN | MSigDB lists | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN | 189 | 29 | 15632 | 1249 |
Prdm1,Mcm10,Tpi1,Mdfic,Bcl2a1b,Cyfip1,Irf4,Casp3,Carhsp1,Cish,Rhoq,Errfi1,Fgl2,Bcl2a1d,C3,Ell2,Odc1,Serpinb9,Lyn,Bcl2a1a,Ccl4,Glrx,Txn1,Snx10,Myadm,Irf8,Hopx,Gem,Plscr1 |
| 5.025e-04 | -7.60 | PROTEASOME | prints domains | PR00141 | 7 | 4 | 5821 | 374 |
Psmb10,Psmb9,Psmb8,Psmb6 |
| 5.028e-04 | -7.60 | regulation of wound healing | biological process | GO:0061041 | 140 | 21 | 20694 | 1406 |
Gja1,Syk,Ptger4,Ubash3b,Pdgfb,Plpp3,Prkce,Pdpn,Hopx,Serpine1,Cav1,Lyn,Plau,Plek,Ccl2,Adrb2,Cd34,Thbs1,Enpp4,Ptprj,Cdkn1a |
| 5.046e-04 | -7.59 | mouse chr11|11 B1.2 | chromosome location | mouse chr11|11 B1.2 | 32 | 8 | 24173 | 1464 |
Tgtp1,Irgm1,Ifi47,Psme2b,Olfr56,9930111J21Rik1,Gm5431,9930111J21Rik2 |
| 5.049e-04 | -7.59 | GO_REGULATION_OF_WOUND_HEALING | MSigDB lists | GO_REGULATION_OF_WOUND_HEALING | 120 | 21 | 15632 | 1249 |
Ubash3b,Adrb2,Lyn,Ptger4,Enpp4,Plaur,Tnfaip3,Plau,Cd34,Thbs1,Serpinb2,Plat,Hopx,Cav1,Serpine1,Plek,Syk,Gja1,Edn1,Pdgfb,Prkce |
| 5.077e-04 | -7.59 | organelle membrane | cellular component | GO:0031090 | 2019 | 174 | 20747 | 1409 |
Tgtp2,Itpr1,Mosmo,Rap1gap2,Osbpl3,Higd1a,Tpst1,Gramd1a,Phlpp2,Rab32,Dst,Snx10,Cd38,Snx2,Bcl2a1d,Treml4,Cept1,Slc25a12,Sema4c,Bcl2a1a,Tgtp1,Rmdn3,Ric1,Traf2,Rap2c,Dhrs9,Glipr2,Sco1,Mul1,Rab19,Aftph,Slc37a3,Mx2,Rubcnl,Pcx,Acsl5,Zc3h12a,Rrbp1,H2-Eb1,Prkce,Slc29a3,Phf11c,Gch1,Dtx2,1600014C10Rik,Gk,Sh3bgrl2,Phf11b,Src,Phf11a,Fcho2,Mx1,AA467197,Trim14,Nr4a1,Myo1b,Slc16a3,Ch25h,Ankrd17,Ldlr,Ifi47,Bnip3,Nlrp3,Snn,Sirt1,Wdr59,Syne2,F830016B08Rik,Pml,Tspo,Rhbdf2,Gm5431,Armcx6,Cop1,Cnp,Trib3,Chmp4b,Ppp1r15a,Slc25a37,Bcl2a1b,Gm12185,Ehd1,Dusp2,Srgn,Sod2,Rffl,Ednrb,Tapbp,Dnajb2,Nos2,Ero1l,Ptger4,Fgr,Sec24a,Mtdh,Tor1aip1,Igtp,Rtn1,Mgat1,Whamm,Golga3,Sphk1,Irgm2,Slc25a22,Rnf139,Hk2,Ext1,Tomm70a,Phf11d,Stx6,Pmepa1,Mcoln2,Phlpp1,Lyn,Sec24b,Gpd2,Kmo,Lnpep,Fut8,Acsl1,Abcc1,Slc25a25,Prpf38a,Tent4a,Acpp,Tap1,Cox18,Stat3,Hk1,Pgap2,Trim13,Ccnd2,Lnpk,Rab21,Plekhn1,Slc44a1,Rsad2,Fndc3a,Irgm1,Slc48a1,Cav1,Ass1,Dpy19l1,Smox,Pigv,Prnp,Plpp3,Cd274,Agpat4,Ikbke,Rab10,Nck1,H2-Q6,Tap2,Slc15a3,Rab9,Tmtc2,Abcc4,Sgms2,Spire1,Gja1,Vrk2,Pikfyve,H2-Q7,Tmem178,Pnpt1,Gm4951,Slc30a1,Iigp1,H2-Q4,Tmem67,9930111J21Rik1,Psd,Gm4841 |
| 5.078e-04 | -7.59 | Hematopoietic cell lineage | KEGG pathways | ko04640 | 93 | 19 | 7931 | 713 |
Il6,Itga5,Il4ra,Cd38,H2-Ab1,Cd55,Il1a,Il1b,H2-Eb1,Tnf,Csf1,H2-Aa,Fcgr1,Csf3r,Csf3,Itga4,Kitl,Cd34,Cd14 |
| 5.078e-04 | -7.59 | Hematopoietic cell lineage | KEGG pathways | mmu04640 | 93 | 19 | 7931 | 713 |
Csf1,Fcgr1,H2-Aa,H2-Ab1,Il1a,Cd55,Il4ra,Cd38,Il6,Itga5,Tnf,H2-Eb1,Il1b,Itga4,Cd14,Kitl,Cd34,Csf3r,Csf3 |
| 5.080e-04 | -7.58 | GO_MODIFICATION_OF_MORPHOLOGY_OR_PHYSIOLOGY_OF_OTHER_ORGANISM | MSigDB lists | GO_MODIFICATION_OF_MORPHOLOGY_OR_PHYSIOLOGY_OF_OTHER_ORGANISM | 80 | 16 | 15632 | 1249 |
Serpinb9,Zc3h12a,Kpna3,Zc3hav1,Trem1,Ccl4,Tnip1,Jun,Casp8,Ccl5,Bcl2l11,Itgav,Eif2ak2,Pcx,Hdac1,Rab9 |
| 5.119e-04 | -7.58 | GO_REGULATION_OF_P38MAPK_CASCADE | MSigDB lists | GO_REGULATION_OF_P38MAPK_CASCADE | 25 | 8 | 15632 | 1249 |
Gadd45b,Hsph1,Ezr,Zc3h12a,Phlpp1,Rasgrp1,Gadd45g,Bmp2 |
| 5.120e-04 | -7.58 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 | 65 | 14 | 15632 | 1249 |
Ifit1bl2,Ifit1bl1,Psmb8,Casp1,Psmb9,Irf7,Ctsc,Pla2g4a,Tmod3,Isg15,Cd83,Pkp4,Ahr,Mdfic |
| 5.120e-04 | -7.58 | GO_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | 65 | 14 | 15632 | 1249 |
Kdr,Thbs1,Sdc4,Ptprj,Ptk2,Mmp14,Slc9a1,Acvrl1,Rapgef2,Gja1,Src,Tnf,Cav1,Fzd5 |
| 5.120e-04 | -7.58 | BOYLAN_MULTIPLE_MYELOMA_D_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_DN | 65 | 14 | 15632 | 1249 |
Atp10a,Dram1,Casp7,Atp11a,Cmpk2,Casp1,Csrp1,Abtb2,St3gal5,Pstpip2,Ksr1,Tdrd7,Nfkbie,Arhgap26 |
| 5.136e-04 | -7.57 | humoral immune response | biological process | GO:0006959 | 180 | 25 | 20694 | 1406 |
Notch2,Cxcl3,Ifnb1,Cxcl11,C1rl,Cxcl2,Rgcc,Ifna1,C1ra,C3,Cd55,Traf3ip2,Notch1,Cxcl9,Slpi,Cxcl10,Ifna5,Ifna2,Cxcl1,Ifna4,Tnf,Ifna6,Pf4,H2-Ab1,Ccl2 |
| 5.174e-04 | -7.57 | BIOCARTA_EGF_PATHWAY | MSigDB lists | BIOCARTA_EGF_PATHWAY | 31 | 9 | 15632 | 1249 |
Fos,Stat2,Jun,Map2k1,Map2k4,Stat5a,Stat1,Stat4,Stat3 |
| 5.174e-04 | -7.57 | GO_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION | 31 | 9 | 15632 | 1249 |
Pdgfb,Rap2c,Pdgfc,Vegfc,Errfi1,Mvp,Src,Cav1,Jun |
| 5.174e-04 | -7.57 | GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | MSigDB lists | GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | 31 | 9 | 15632 | 1249 |
Il1b,Il6,Hif1a,Il1a,Ptgs2,Adora2b,Nox1,Ccl12,C3 |
| 5.174e-04 | -7.57 | DORSAM_HOXA9_TARGETS_DN | MSigDB lists | DORSAM_HOXA9_TARGETS_DN | 31 | 9 | 15632 | 1249 |
Serpinb9,Lyn,Jun,Junb,Glrx,Clcn7,Sdc4,Myc,Cish |
| 5.174e-04 | -7.57 | TGCCTTA_MIR124A | MSigDB lists | TGCCTTA_MIR124A | 508 | 62 | 15632 | 1249 |
Serp1,Mecp2,Egr2,Rffl,Dennd1b,Stat3,Nr3c1,Sertad3,Arg2,F11r,Myo10,Plagl2,Cd164,Ncoa7,Dusp6,Myadm,Slc7a8,Slc4a7,Slc31a2,Eya4,Wdfy1,Rab10,Nrp2,Gpr85,Frmd4a,Phf6,Slc31a1,Pcgf5,Larp1,Abcc4,Osbpl3,Tmem184b,Bcl2l11,Ccl12,Rai14,Kcnj2,Spry2,Ccnd2,Palld,Abr,Ahr,Angpt1,Slc16a1,Slc48a1,Cep350,Pid1,Ednrb,P4ha1,Tor3a,Kctd12,Jag1,Sirt1,Akt3,Cnn3,Acsl1,Map2k4,Cacnb3,Ell2,Mtdh,Pmepa1,Lhx2,Rbms1 |
| 5.199e-04 | -7.56 | GO_POSITIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 112 | 20 | 15632 | 1249 |
Zc3h12a,Tlr3,Tlr9,Tlr2,Il12b,Sphk1,Il18,Ddx58,Ptgs2,Bambi,Hcls1,Jak2,Il1b,Tnf,Tnfsf14,Il6,Slc9a1,Rbpms,Mdm2,Csf3 |
| 5.199e-04 | -7.56 | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | 112 | 20 | 15632 | 1249 |
Sgcb,Clic4,Dcbld2,Ptges,Armc8,Prpf4,Nfil3,Palld,Nek6,Stxbp1,Socs3,Plagl1,Rcan1,Rab21,Cnn3,Ube2e2,Slc31a2,Gramd1a,Psip1,Cd302 |
| 5.213e-04 | -7.56 | positive regulation of reactive oxygen species biosynthetic process | biological process | GO:1903428 | 59 | 12 | 20694 | 1406 |
Icam1,Tlr2,Ptgs2,Tnf,Sod2,Jak2,Tlr6,Klf2,Klrk1,Il6,Ass1,Il1b |
| 5.217e-04 | -7.56 | positive regulation of oxidoreductase activity | biological process | GO:0051353 | 51 | 11 | 20694 | 1406 |
Cox17,Edn1,Htr2b,Lgals9,Ppm1k,Nod1,Nod2,Il1b,Tnf,Gch1,Ripk3 |
| 5.217e-04 | -7.56 | regulation of lipid kinase activity | biological process | GO:0043550 | 51 | 11 | 20694 | 1406 |
Lyn,Fpr2,Ppp2r5a,Nod2,Flt1,Pdgfrb,Src,Fgr,Pik3r5,Rbl1,Pdgfb |
| 5.247e-04 | -7.55 | kinase inhibitor activity | molecular function | GO:0019210 | 58 | 12 | 20217 | 1400 |
Trib1,Rhoh,Casp3,Spred1,Prkar2b,Wars,Nck1,Trib3,Cdkn1a,Cdkn2d,Socs1,Kat2b |
| 5.265e-04 | -7.55 | positive regulation of phosphatidylinositol 3-kinase activity | biological process | GO:0043552 | 29 | 8 | 20694 | 1406 |
Pdgfrb,Flt1,Src,Fgr,Pdgfb,Lyn,Fpr2,Nod2 |
| 5.296e-04 | -7.54 | positive regulation of natural killer cell mediated cytotoxicity | biological process | GO:0045954 | 36 | 9 | 20694 | 1406 |
Klrk1,Raet1e,Rasgrp1,Il12b,Nectin2,Il18rap,Pvr,Stat5a,H60b |
| 5.296e-04 | -7.54 | positive regulation of natural killer cell mediated immunity | biological process | GO:0002717 | 36 | 9 | 20694 | 1406 |
Klrk1,Raet1e,Il12b,Rasgrp1,Il18rap,Nectin2,Pvr,Stat5a,H60b |
| 5.299e-04 | -7.54 | LINDGREN_BLADDER_CANCER_HIGH_RECURRENCE | MSigDB lists | LINDGREN_BLADDER_CANCER_HIGH_RECURRENCE | 44 | 11 | 15632 | 1249 |
Col4a2,Nrp2,Vcam1,Adam19,Vcan,Birc3,Nr4a1,Col18a1,Csrp1,Myadm,Ubr4 |
| 5.299e-04 | -7.54 | REACTOME_TCR_SIGNALING | MSigDB lists | REACTOME_TCR_SIGNALING | 44 | 11 | 15632 | 1249 |
H2-Aa,Vasp,Nfkbia,H2-Eb1,Ikbkg,Lcp2,Evl,Malt1,Nck1,Ripk2,Tab2 |
| 5.299e-04 | -7.54 | MODULE_273 | MSigDB lists | MODULE_273 | 44 | 11 | 15632 | 1249 |
Cebpd,Nr3c1,Snapc1,Polr2g,Nmi,Rel,Irf1,Mafg,Nfkb1,Ppa1,Stat1 |
| 5.302e-04 | -7.54 | JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | REACTOME pathways | R-MMU-450321 | 18 | 7 | 8608 | 757 |
Tab2,Map2k4,Ripk2,Irak2,Nod1,Ikbkg,Nod2 |
| 5.319e-04 | -7.54 | GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS | MSigDB lists | GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS | 96 | 18 | 15632 | 1249 |
Nampt,Eno2,Hk1,Eno1,Pnp2,Pdss1,Prdx5,Hk2,Nox1,Ldha,Tpi1,Pgm1,Kmo,Pfkfb3,Pfkl,Hk3,Me1,Pgk1 |
| 5.336e-04 | -7.54 | SOUCEK_MYC_TARGETS | MSigDB lists | SOUCEK_MYC_TARGETS | 6 | 4 | 15632 | 1249 |
Ccl12,Ccl5,Cxcl1,Klf6 |
| 5.341e-04 | -7.53 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN | 172 | 27 | 15632 | 1249 |
Tap1,Fcgr1,Cd74,Psmb10,Psme1,H2-Q7,Psma6,Tapbp,Abcb1a,H2-Q6,Psmd10,Psmb9,Dync1h1,H2-Q4,Cenpe,Itgav,Sec24b,Sec24a,Kif3c,H2-Ab1,Psmb6,Psme2,H2-Aa,Tap2,Psmb8,H2-Eb1,Lnpep |
| 5.341e-04 | -7.53 | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_6H_DN | 172 | 27 | 15632 | 1249 |
Acvr1b,Rab20,Ptk2,Egr3,Znrf1,Osbpl3,Slfn9,Bambi,Gca,Vps54,Birc3,Nampt,Rabgef1,4930523C07Rik,Junb,Tuba4a,Nfkbid,Ksr1,Intu,Dmxl2,Ifit1,Dnaja1,Cd40,Tiparp,Cdyl2,Slfn8,Dusp8 |
| 5.341e-04 | -7.53 | GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_DN | MSigDB lists | GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_DN | 172 | 27 | 15632 | 1249 |
Itga5,Dram1,Il12b,Cdc42ep4,Asb13,Mefv,Tnip3,Clic4,Bcl2a1a,Il1b,Dcbld2,Gja1,Slc13a3,Hopx,Lcp2,Cav1,Fabp7,Ppp2r3a,Stat4,Bst1,Aldh1b1,Bcl2a1b,Lrp4,Flt1,Bcl2a1d,Tra2a,Ogfrl1 |
| 5.341e-04 | -7.53 | GSE3982_EOSINOPHIL_VS_BASOPHIL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_BASOPHIL_UP | 172 | 27 | 15632 | 1249 |
P4ha2,Txnrd1,Slc7a11,Acpp,Rgs14,Dock4,Csf3r,P2ry13,Rbbp8,Tiparp,Phactr4,Trim13,Bfar,Fcgr1,Cd80,Clec4e,Htr2a,Dach1,S100a8,Psd4,Inpp5b,Jag1,Vasp,Trib1,Bambi,Rgs1,Snn |
| 5.354e-04 | -7.53 | hemostasis | biological process | GO:0007599 | 112 | 18 | 20694 | 1406 |
Enpp4,Ptprj,C3,Axl,F10,Plek,Procr,Pf4,Evl,Cx3cl1,Ap3b1,Papss2,Slc7a11,P2ry12,Stxbp1,Lnpk,Stxbp3,Ubash3b |
| 5.365e-04 | -7.53 | VERRECCHIA_EARLY_RESPONSE_TO_TGFB1 | MSigDB lists | VERRECCHIA_EARLY_RESPONSE_TO_TGFB1 | 58 | 13 | 15632 | 1249 |
Cd82,Plat,Rnd3,Notch2,Rhoc,Marcksl1,Icam1,Rhoq,Mmp14,Vcan,Serpine1,Zyx,Timp1 |
| 5.365e-04 | -7.53 | GO_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS | 58 | 13 | 15632 | 1249 |
Hif1a,Nr4a3,Hp,Nox1,Sirt1,Met,Fut8,Hsph1,Tnf,Txn1,Sod2,Sesn3,Gch1 |
| 5.377e-04 | -7.53 | integrin-mediated signaling pathway | biological process | GO:0007229 | 76 | 14 | 20694 | 1406 |
Fgr,Syk,Fut8,Itgav,Itga5,Itga4,Itgal,Src,Itga9,Plek,Zyx,Ptk2,Itgb8,Isg15 |
| 5.393e-04 | -7.53 | Downstream TCR signaling | REACTOME pathways | R-MMU-202424 | 88 | 18 | 8608 | 757 |
Psmb9,Nfkbia,H2-Ab1,Psmb6,Psme1,Nfkb1,Psmb8,Ripk2,Psmb10,Ikbkg,Psme2,Tab2,Psma6,H2-Eb1,Psmd10,H2-Aa,Malt1,Psme2b |
| 5.410e-04 | -7.52 | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | 181 | 28 | 15632 | 1249 |
Rbm43,Olfml3,Lrp8,Tpx2,Peli1,Mmp14,Ctsc,Gclm,1110038F14Rik,Gsr,Apobec3,Dpy19l1,Cx3cr1,Aoah,P2ry12,Inpp1,Nfxl1,Abcc1,Hsd17b7,Lyn,Lox,Trim21,Ube2l6,Snx2,G3bp2,Sesn3,Ltbp2,Pid1 |
| 5.410e-04 | -7.52 | GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP | 181 | 28 | 15632 | 1249 |
Arf4,Ralgds,Socs7,Cpeb4,Ptgir,Grina,Il12b,Adrb2,Gpr132,Procr,Bst1,Pla2g7,Stx6,Rgl1,Rnf31,Gdf15,F10,Hvcn1,Evl,Mapkapk2,Aldh1b1,Sell,Gclm,Optn,Slc7a11,Ddhd1,Ppp1r14b,Zyx |
| 5.410e-04 | -7.52 | GSE13229_MATURE_VS_INTMATURE_NKCELL_UP | MSigDB lists | GSE13229_MATURE_VS_INTMATURE_NKCELL_UP | 181 | 28 | 15632 | 1249 |
Herc6,Tlr3,Etnk1,Slc43a3,Rcsd1,Cxcl1,Igf1r,Nfkb1,Tnfsf14,Cd274,Inpp5b,Stat4,Parp12,Ppp2r3a,Spint2,Egln3,Aim2,Slco3a1,Fgr,Kif9,Ripk3,Tnf,Eif2ak2,Zswim4,Gbp9,Gbp4,Fchsd2,Sele |
| 5.410e-04 | -7.52 | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_DN | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_DN | 181 | 28 | 15632 | 1249 |
Il10,Ttc9c,Ahrr,Mmd,Pdlim7,Plscr1,Frmd4a,Cd200,Ell2,Il15ra,Fmnl2,Bcl2a1a,Tnfsf10,Swap70,Itpr1,Ttc39c,Zmynd15,Plac8,Bcl2a1b,Chst11,Cpd,Bcl2a1d,Casp3,Tor1aip2,Nek6,Cd38,Gda,Vcpip1 |
| 5.422e-04 | -7.52 | BROWNE_HCMV_INFECTION_20HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_20HR_UP | 208 | 31 | 15632 | 1249 |
Hspa2,Dusp8,Abcb1a,Dnaja1,Ets2,Plagl2,Mark2,Zbtb5,Pml,Xaf1,Oas2,Alas1,Trim21,Trim26,Lcn2,Ogfr,Rel,Tuba4a,Brd2,Ccr1,Pdk3,Tfec,Nfkb2,Rap2c,Inpp1,Map2k4,Lyn,Nr4a3,Kif5c,Casp7,Rnf19b |
| 5.425e-04 | -7.52 | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 129 | 22 | 15632 | 1249 |
Ube2e1,Psme1,Parp10,Psmb6,Pml,Isg15,Psmb10,Tspo,Gclc,Tnfaip3,Dnajb2,Psmb8,N4bp1,Cav1,Psmb9,Psmd10,Hspa1a,Dnaja1,Trim21,Prkce,Psme2,Psma6 |
| 5.444e-04 | -7.52 | GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_UP | 190 | 29 | 15632 | 1249 |
Txn1,Pde4b,Dusp6,Ccl5,Csrp1,Myo1b,Oas1a,Jag1,Csf3,Oas1g,Trib3,Il18,Fam102b,Sh3bgrl2,Igf2bp2,P4ha2,Psmb9,Dock4,Irf4,Gbp9,Gbp4,Samd9l,Slc30a4,Atp11a,Pttg1,Usp18,Cd38,Dnase1l3,Atp11b |
| 5.444e-04 | -7.52 | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_DN | MSigDB lists | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_DN | 190 | 29 | 15632 | 1249 |
Kdm6b,Egr3,Kif5c,Cd200,Stat1,Igf1r,Rnaset2b,Snn,Ldlr,Rnaset2a,Atp6v1d,Map4k4,Trim56,Mmd,Rasgrp1,Egln3,Ext1,Bcl9,Hif1a,Zfp281,Plagl1,Cyth3,Cdk5r1,Cd83,Tspan3,Bcl6,Fam43a,Cers6,Egr2 |
| 5.444e-04 | -7.52 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_UP | 190 | 29 | 15632 | 1249 |
Hdc,Mov10,Nfkbib,Plscr1,Ext1,Mmd,Cpeb4,Ebi3,Rab20,Gpr85,Serpinb9,Osgin2,Plat,Plcl2,Cflar,Znrf1,Il1rn,Lhx2,Clmp,Nr4a1,Ehd1,Slc44a1,Edn1,Phgdh,Psd,Aebp2,Irs2,Ccl22,Apaf1 |
| 5.444e-04 | -7.52 | GSE43955_1H_VS_60H_ACT_CD4_TCELL_DN | MSigDB lists | GSE43955_1H_VS_60H_ACT_CD4_TCELL_DN | 190 | 29 | 15632 | 1249 |
Irf1,Map3k8,Fam111a,Ptger4,Il13ra1,Nfil3,Dr1,Il1rn,Ppp1r15a,Casp4,Gja1,Plscr1,Slc30a1,Il4ra,Socs1,Slc30a4,Ch25h,Cdkn2d,Nek6,Rhoh,Myd88,Tal2,Gadd45b,Ccl12,Errfi1,C1ra,Dtnb,Ppp2r5a,Tnfsf8 |
| 5.444e-04 | -7.52 | GSE27786_NKCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_NKCELL_VS_NKTCELL_UP | 190 | 29 | 15632 | 1249 |
Gnb4,Prdx1,Mthfr,Nfkbiz,Irf2,Tmem176b,Dhx58,Stard5,Ppp2r5a,Pnp2,Casp3,Gsdmd,Chd9,Fam20c,Cmklr1,Notch2,Nfxl1,Trib1,Ptgir,Dusp5,Ebi3,Rnf19b,Slamf9,Ext1,Rel,Slc31a2,Jarid2,Hsd17b12,Txn1 |
| 5.447e-04 | -7.52 | GO_RESPONSE_TO_INSULIN | MSigDB lists | GO_RESPONSE_TO_INSULIN | 199 | 30 | 15632 | 1249 |
Egr1,Fabp3,Irs2,Hif1a,Phip,Kat2b,Pde3b,Ccl12,Src,Ptpn2,Egr2,Rhoq,Il6,Errfi1,Socs3,Max,Lyn,Trib3,Gfpt1,Socs7,Igf1r,Ccl5,Nampt,Atp6v1d,Il10,Stxbp3,Pdgfb,Rab10,Slc9a1,Sirt1 |
| 5.448e-04 | -7.52 | intracellular non-membrane-bounded organelle | cellular component | GO:0043232 | 4060 | 324 | 20747 | 1409 |
Parp3,Zyx,Snx10,Flnb,Rab3ip,Plk3,Dst,Nsd3,Cenpj,Samhd1,Nes,Cep350,Hap1,Pcgf5,Ifi209,Irf4,Ift57,Sbds,Cnn2,Mecp2,Ppp4r2,Itpr1,Rai14,Rap1gap2,Eef1e1,Taf4b,Cited2,Larp1,Ddx4,Mov10,Igf2bp2,Tnks1bp1,Tra2a,Arid5a,Myc,Mndal,Sgcb,Ddx60,Klf6,Intu,Ifi207,Mapkapk2,Sp140,Ciapin1,Atp6v1d,Myo10,Map2k1,Nr3c1,Fcgr2b,Lad1,Nfkbiz,Cutc,Sco1,Gpsm2,Trip13,Gypc,Acsl5,Pdk3,Ubr4,Crbn,Zc3h12a,Stau1,Tpx2,Smg7,Tulp3,Phf6,Ift22,Atf3,Fnbp1l,Pik3r5,Rmdn3,Nr1h3,Tyk2,Mcm9,Kif5c,Homer1,Hdac1,Etv3,Psip1,Cdkn1a,Ppp2r5a,Clmp,Xrn1,Fcho2,Pde4b,Ctsc,Ikzf1,Noct,G3bp2,Src,Keap1,Mark2,Dync1h1,Dyrk2,Jmjd6,Dcp1a,Myo1b,Snapc1,Prkar2b,Gng12,Tcf4,Ifi204,Trim12c,Rnf19a,Mefv,Rgcc,Ikbkg,Jak2,Txnrd1,Hmgn3,Asf1a,Sap30,Prkce,Prdx1,Kmt5a,Mtus1,Myadm,Hspa2,Atp2b4,Daam1,Atm,Rrs1,Tma16,Radx,Rnd1,Marcksl1,Top3a,Hsph1,Pml,Rcl1,Resf1,Grk3,Mvp,Swap70,Kif9,Frmd4a,Cdk5r1,Spry2,Phlda1,Rbl1,Dcp2,Sele,Trib3,Cnp,Wdr43,Clic4,Noc4l,Fam111a,Cdyl,Klf2,Mdn1,Ankrd17,Tmod3,Irf1,Jun,Ifi214,Dync1i2,Sirt1,Syne2,Ccdc88b,Junb,Dnaja1,Ccdc86,Bcl2l11,Fgr,Mtdh,Ncoa5,Psmd10,Malt1,Ptk2,Polr2g,Isg20,Cacna1d,Rabgef1,Prdm9,Marcks,Rac3,Icosl,Whamm,Tuba4a,Golga3,Dbnl,Carmil1,Socs1,Serp1,Sod2,Max,Arhgap26,Slc2a1,Ifi213,Ehd1,Vcam1,Hat1,Micall2,Smc5,Nos2,Bcl6,Birc2,Arl4a,Trip10,Ripk2,Triobp,Flt1,Kif3c,Mid1,Slc16a1,Katna1,Pstpip2,Tdrd7,Lipe,Rbpms,Traf5,Tap1,Sipa1l1,Rilpl1,Riox2,Mcm10,Gem,Uaca,Mdm2,Vasp,Evl,Tpm4,Lrp8,Tent4a,Hck,Adar,Cdc42ep4,Timeless,Rgs14,Stat1,N4bp1,Hmox1,Rhoq,Rhof,Fscn1,Pla2g4a,Daxx,Sdc4,Pim1,Nfkbie,Nek6,Procr,Mmp14,Frmd6,Nlrc5,Eif2ak2,Hif1a,Ezr,Lpcat2,Dennd2a,Dek,Hmga1,Hilpda,Cenpe,Palld,Hspa1a,Pkp4,Oasl1,Nck1,Adora2a,Hcls1,Plk2,Mcmbp,Kitl,Ifi205,Sass6,Sertad3,Ccnd2,Relb,Rims3,Stat3,Etv6,Csrp1,Ep400,Kat2b,Cav1,Ppp1r12b,Rbbp8,Psma6,Ago3,Dock4,Plekhn1,Rsad2,Cep85l,Nod2,Gbp2,H3f3b,Tcea1,Pnpt1,Ifi203,Zfp36,Ifi208,Hmga2,Ddx58,Parp9,Gja1,Sqstm1,Trim36,Cnn3,Pdlim7,Cgas,Sinhcaf,Kdm4a,Ifi211,Tmem67,Mxd1,Tlk2,Clic5,Mapkbp1,Ccne1,Carhsp1,Stxbp1,Cdc42ep2,Actb,Mrpl52,Mdfic,Parp10,S100a8,Rpgrip1l,Slc7a11,Spire1,Plscr1,Setdb2 |
| 5.450e-04 | -7.51 | GO_CELLULAR_RESPONSE_TO_FATTY_ACID | MSigDB lists | GO_CELLULAR_RESPONSE_TO_FATTY_ACID | 51 | 12 | 15632 | 1249 |
Edn1,Tnc,Prkce,Il1b,Tnfsf4,Src,Ptger4,Pdk3,Ass1,Zc3h12a,Pid1,Ptafr |
| 5.450e-04 | -7.51 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | 51 | 12 | 15632 | 1249 |
Sema3c,Rictor,Il18rap,Csf1,Plscr1,Ifi44,Xrn1,Fas,Cd38,Olr1,Vcam1,Orai2 |
| 5.450e-04 | -7.51 | REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE | MSigDB lists | REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE | 51 | 12 | 15632 | 1249 |
Psme1,Psmb6,Psmb10,Cdkn1a,Psmb8,Atm,Ccne1,Psmb9,Psmd10,Psme2,Mdm2,Psma6 |
| 5.453e-04 | -7.51 | GO_RESPONSE_TO_ACID_CHEMICAL | MSigDB lists | GO_RESPONSE_TO_ACID_CHEMICAL | 311 | 42 | 15632 | 1249 |
Lrp11,Ptges,Il1b,Ptger4,Tnfsf4,Cpeb4,Zc3h12a,Ptgs2,Lyn,Acsl1,Ptafr,Pdgfb,Zeb1,Sh3bp4,Pdk3,Ccl5,Pid1,Asns,Pdgfrb,Ptch1,Atp2b4,Cd38,Pdgfc,Fas,Mthfr,Cdkn2d,Col18a1,Egr1,Icam1,Hif1a,Fabp3,Socs1,Edn1,Tnc,Casp3,Prkce,Il6,Dusp1,Src,Tnf,Ccl12,Ass1 |
| 5.519e-04 | -7.50 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 245 | 35 | 15632 | 1249 |
Pcdh7,Vcam1,Orai2,Fam102b,Serpinb2,Mob3c,Ptprj,Smox,Acvr1b,Ttc39b,Serpinb9,Frmd4a,Trim26,Akt3,Ddit4,Srxn1,Atxn7l1,Car13,Tmem26,Rgl1,4930523C07Rik,Sgk3,Gnb4,Slc48a1,Gda,Tle3,Hhex,Sphk1,Bbx,Prkce,Cish,Optn,Kdm5b,Pcx,Klf6 |
| 5.573e-04 | -7.49 | GO_PROTEIN_OLIGOMERIZATION | MSigDB lists | GO_PROTEIN_OLIGOMERIZATION | 409 | 52 | 15632 | 1249 |
Gfpt1,Pfkl,Igf1r,Dgkh,Trim21,Slc9a1,Pdss1,Oas1a,Rasgrp1,Kctd12,Birc3,Cav1,Casp8,Pnpt1,Chmp4b,Me1,Samhd1,Evl,Fas,Prnp,Nlrp3,Kcnj2,Nod2,Sod2,Sqstm1,Nlrc4,Ikbke,Keap1,Zc3h12a,Hmox1,Oas1g,Kcna3,Stxbp3,Snx2,Vasp,H2-Eb1,Gch1,Gja1,Ccl5,Nod1,Cutc,Ripk3,Apaf1,Tnfaip3,Malt1,Trim12c,Mlkl,Acvrl1,Ehd1,Lrp4,Traf2,Birc2 |
| 5.598e-04 | -7.49 | regulation of ossification | biological process | GO:0030278 | 233 | 30 | 20694 | 1406 |
Fam20c,Cebpd,Pdlim7,Ptk2,Isg15,Notch1,Gja1,Ptch1,Bcor,Kremen1,Csf1,Srgn,Ahr,Pbx1,Adrb2,Noct,Ccr1,Bmp2,Intu,Acvr1,Il6,Ptger4,Egr2,Hif1a,Lrp4,Rsad2,Tnf,P2ry2,Jag1,Ifi204 |
| 5.610e-04 | -7.49 | GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP | 155 | 25 | 15632 | 1249 |
B3gnt5,Fcgr2b,Upp1,Kat2b,Znrf3,Socs1,Tmem176b,Ripk3,Rab3ip,Myo10,Gnb4,Sdc4,Rnd3,Gna15,Ascc3,Syne2,Tmem176a,Cnn3,Cysltr2,Acvr1b,Mmp9,Plaur,Igf1r,Sh3bgrl2,Ikbke |
| 5.610e-04 | -7.49 | GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN | 155 | 25 | 15632 | 1249 |
Bst1,Lcn2,Plek,S100a8,Plaur,Il1rn,Clec5a,Fpr1,Acsl1,Rnf19b,Socs3,Ptgir,Il13ra1,Vcan,Cpd,Fos,Csf3r,Bcl6,Cd302,Zyx,Slc25a37,Slc16a1,Cd14,Tspo,Egr1 |
| 5.610e-04 | -7.49 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP | 155 | 25 | 15632 | 1249 |
Tnfsf8,Otud1,Jun,Tiparp,Parp8,Dusp1,Dhrs9,Hck,Kat2b,Mul1,Irs2,Nfkbiz,Itga4,Ier2,Rnf139,Rap1gap2,Maff,Klf2,Plek,Map4k4,Snn,Whamm,Kcna3,Pim1,Socs3 |
| 5.610e-04 | -7.49 | GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_UP | MSigDB lists | GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_UP | 155 | 25 | 15632 | 1249 |
Rap2c,Thbs1,Sec24a,Ap3m2,Prkar2b,Lrrc8c,Cpeb4,Socs3,Scyl2,Cd200,Map3k8,Zeb1,Arl5b,Mmd,Usp12,Nampt,Sesn3,Rel,Gem,Pim3,Sdc4,Prdm1,Ch25h,Nfkbiz,Peli1 |
| 5.666e-04 | -7.48 | regulation of muscle cell differentiation | biological process | GO:0051147 | 161 | 23 | 20694 | 1406 |
Notch1,Zeb1,Mmp14,Trip10,Sirt1,Gdf15,Ccl8,Tomm70a,Tnfsf14,Il4ra,Edn1,Ankrd17,Bmp2,Nr3c1,Daxx,Hopx,Cflar,Ehd1,Sod2,Cxcl10,Cxcl9,Pdgfb,Mecp2 |
| 5.698e-04 | -7.47 | FCERI mediated NF-kB activation | REACTOME pathways | R-MMU-2871837 | 74 | 16 | 8608 | 757 |
Psme1,Psmb6,Nfkbia,Rasgrp1,Psmb9,Psmd10,Malt1,Psme2b,Psme2,Lyn,Tab2,Psma6,Psmb10,Ikbkg,Nfkb1,Psmb8 |
| 5.757e-04 | -7.46 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_DN | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_DN | 164 | 26 | 15632 | 1249 |
P2ry14,Ccnd2,Cd74,Ch25h,Mcmbp,Samhd1,Fcgr1,Cers6,Gsr,Ythdf1,Fgl2,Batf2,Ctsc,Slamf8,Tgfbi,Ppa1,Psmb6,H2-Ab1,Trafd1,Idi1,Ascc3,Dcun1d3,Wars,Psme2,H2-Aa,Ube2l6 |
| 5.757e-04 | -7.46 | GSE10325_BCELL_VS_MYELOID_UP | MSigDB lists | GSE10325_BCELL_VS_MYELOID_UP | 164 | 26 | 15632 | 1249 |
Stap1,Optn,Sp140,Ezr,Gpr18,Tspan3,Zbtb5,Rras2,Traf5,Rhoh,Evl,Il4ra,Isg20,Rasgrp1,Syne2,Pde4b,Birc3,4930523C07Rik,Rabgef1,Asns,Adam19,Zhx2,Pim2,Cd200,Arid5b,Odc1 |
| 5.757e-04 | -7.46 | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 164 | 26 | 15632 | 1249 |
Kctd12,Casp2,Inpp5b,Tlr1,Vps54,4930523C07Rik,Card6,Tmem219,Mppe1,Aida,Hdac1,Sdc2,Cebpd,Casp3,Top3a,Fam43a,Rnf114,Abcc5,Dhrs9,Hvcn1,Gnb4,Pde3b,St3gal6,Nck1,Hhex,Tlr6 |
| 5.757e-04 | -7.46 | GSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_UP | MSigDB lists | GSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_UP | 164 | 26 | 15632 | 1249 |
Nkiras1,Spata13,Ccnd2,Upp1,Ifih1,Arl4a,Pde3b,Cutc,Nlrc5,Casp1,Gypc,Timp1,Pnp2,S1pr2,Rsad2,Cd55,Pim2,Parp11,Tlr2,Gbp2b,Rgs1,Epsti1,Card6,Tuba4a,Isg20,Il12rb1 |
| 5.757e-04 | -7.46 | GSE32255_UNSTIM_VS_4H_LPS_STIM_DC_UP | MSigDB lists | GSE32255_UNSTIM_VS_4H_LPS_STIM_DC_UP | 164 | 26 | 15632 | 1249 |
Endod1,Ptger4,Cd200,Kcna3,Ttc39b,Fam111a,Tnfsf10,Pkp4,Tagap,Slc4a7,Pdk3,Hopx,Samsn1,Reps1,Csf1,Alas1,Prdm1,Rhoh,Ubash3b,Plagl1,Cd38,Swap70,Tank,Egr2,Itgb8,Dusp4 |
| 5.763e-04 | -7.46 | Prion diseases | KEGG pathways | mmu05020 | 34 | 10 | 7931 | 713 |
Il6,Prnp,Hspa1a,Ccl5,Il1a,Egr1,Il1b,Stip1,Map2k1,Notch1 |
| 5.763e-04 | -7.46 | Prion diseases | KEGG pathways | ko05020 | 34 | 10 | 7931 | 713 |
Il1b,Egr1,Ccl5,Il1a,Hspa1a,Il6,Prnp,Notch1,Map2k1,Stip1 |
| 5.788e-04 | -7.45 | LUI_THYROID_CANCER_CLUSTER_4 | MSigDB lists | LUI_THYROID_CANCER_CLUSTER_4 | 10 | 5 | 15632 | 1249 |
Cd74,Wars,Zyx,H2-Ab1,Nupr1 |
| 5.788e-04 | -7.45 | MODULE_471 | MSigDB lists | MODULE_471 | 10 | 5 | 15632 | 1249 |
Acsl1,Lap3,Asns,Gclc,Gclm |
| 5.788e-04 | -7.45 | BIOCARTA_SODD_PATHWAY | MSigDB lists | BIOCARTA_SODD_PATHWAY | 10 | 5 | 15632 | 1249 |
Tnf,Birc3,Tnfrsf1b,Traf2,Casp8 |
| 5.788e-04 | -7.45 | IIZUKA_LIVER_CANCER_PROGRESSION_G1_G2_UP | MSigDB lists | IIZUKA_LIVER_CANCER_PROGRESSION_G1_G2_UP | 10 | 5 | 15632 | 1249 |
Psme1,Ube2l6,Stat1,Oas2,Trafd1 |
| 5.788e-04 | -7.45 | GO_REGULATION_OF_NECROPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_NECROPTOTIC_PROCESS | 10 | 5 | 15632 | 1249 |
Birc3,Cflar,Ripk3,Cav1,Birc2 |
| 5.824e-04 | -7.45 | Oxidative Stress | WikiPathways | WP412 | 28 | 10 | 4813 | 540 |
Junb,Gsr,Sod2,Fos,Nfkb1,Txnrd1,Hmox1,Nqo1,Gclc,Mt1 |
| 5.835e-04 | -7.45 | GO_MORPHOGENESIS_OF_AN_EPITHELIUM | MSigDB lists | GO_MORPHOGENESIS_OF_AN_EPITHELIUM | 390 | 50 | 15632 | 1249 |
Tnc,Setdb2,Kdm5b,Acvr1,Acvrl1,Src,Plod3,Bmp2,Pbx1,Notch1,Apaf1,Rhoc,Hhex,Pml,Hif1a,Tulp3,Intu,Rab10,Vasp,Fzd1,Mthfd1l,Gja1,Fzd5,Prkx,Clic4,Vegfc,Sec24b,Spry2,Edn1,Mmp14,Myc,Il6,Ift57,Phactr4,Ezr,Flrt3,Sdc4,Csf1,Timeless,Jag1,Met,Il10,Sema3c,Ptch1,Lmo4,Rpgrip1l,Lhx2,Sema4c,Socs3,Itga5 |
| 5.850e-04 | -7.44 | NGF signalling via TRKA from the plasma membrane | REACTOME pathways | R-MMU-187037 | 321 | 46 | 8608 | 757 |
Psme2,Trib3,Cd80,Psma6,Met,Ptk2,Mdm2,Psmb8,Ier3,Psmb6,Dusp4,Dusp6,Prkar2b,Psme1,Dusp5,Rasgrp1,Rapgef2,Pde1b,Irs2,Ppp2r5a,Rictor,Pdgfb,Kitl,Cdkn1a,Jak2,Map2k1,Cd86,Pdgfrb,Ksr1,Il2rg,Psmd10,Phlpp1,Psmb10,Crkl,Psmb9,Mapkapk2,Pik3cd,Src,Phlpp2,Angpt1,Psme2b,Ralgds,Spred1,Nr4a1,Ppp2r1b,Prkce |
| 5.858e-04 | -7.44 | GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_RESTING_CD4_TCELL_UP | MSigDB lists | GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_RESTING_CD4_TCELL_UP | 173 | 27 | 15632 | 1249 |
Stxbp3,Vasp,Tnfrsf1b,Cd86,Cldnd1,Snapc1,Keap1,Ap3m2,Stat1,Cpeb4,Asb13,Rab11fip1,Rab21,Cers6,Nfkbie,Mecp2,Cox17,Tlk2,Dusp1,Nr4a1,Swap70,Rhoh,Col18a1,Mxd1,Nfkbiz,Aim2,Spata13 |
| 5.858e-04 | -7.44 | GSE3982_MAST_CELL_VS_TH1_DN | MSigDB lists | GSE3982_MAST_CELL_VS_TH1_DN | 173 | 27 | 15632 | 1249 |
Sdc4,Hk3,Rbl1,Klf8,Tpx2,Irf4,Peli1,Optn,Chst11,Spsb1,Apobec3,Sp140,Klhl25,Psmb9,Cflar,Pim2,Ak4,Il2rg,Map3k8,Zeb1,Timeless,Nfkbib,Hivep3,Pdk3,Gch1,Tap2,Il10 |
| 5.858e-04 | -7.44 | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_UP | MSigDB lists | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_UP | 173 | 27 | 15632 | 1249 |
Slfn4,Psmb8,Tor3a,Ppp2r3a,Ppp4r2,Psmb6,Larp1,Vrk2,Rap2c,Cflar,Dr1,Slfn3,Dnaja1,Dusp1,Tapbp,Dbnl,Ccdc86,Rnf135,Plagl1,Mcoln2,Usp25,Psme1,Fas,Prpf38a,Rab3ip,Cutc,Cd80 |
| 5.858e-04 | -7.44 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_DN | 173 | 27 | 15632 | 1249 |
Pigv,Arg2,Bcor,Egr1,Dusp14,Gbp2,Prdx1,Dse,Rbbp8,Flt1,Nr4a1,Txnrd1,B3gnt5,Cycs,Nr4a3,Mthfd2,Cd200,Gfi1,Il1rn,Fam102b,Sec24a,Med21,Stx6,Kctd12,Spint2,Phlda1,Nmi |
| 5.858e-04 | -7.44 | GSE29618_PDC_VS_MDC_UP | MSigDB lists | GSE29618_PDC_VS_MDC_UP | 173 | 27 | 15632 | 1249 |
Flnb,Slc7a5,Egln3,Syne2,Dach1,Map4k4,Irf8,Rims3,Irf7,Cmklr1,Adam19,Zhx2,Dck,Dusp5,Odc1,Ctsc,Irf4,Fchsd2,Cers6,Plac8,Ppp1r14b,Slc7a11,Tspan3,Tcf4,Dnase1l3,Mapkapk2,Cdk5r1 |
| 5.870e-04 | -7.44 | PID_SMAD2_3NUCLEAR_PATHWAY | MSigDB lists | PID_SMAD2_3NUCLEAR_PATHWAY | 81 | 16 | 15632 | 1249 |
Hdac1,Dcp1a,Ifnb1,Nr3c1,Sap30,Myc,Il10,Fos,Irf7,Jun,Serpine1,Cdkn1a,Rbl1,Kat2b,Max,Atf3 |
| 5.883e-04 | -7.44 | MILI_PSEUDOPODIA_HAPTOTAXIS_UP | MSigDB lists | MILI_PSEUDOPODIA_HAPTOTAXIS_UP | 470 | 58 | 15632 | 1249 |
Ifi204,Dnajb4,Hmgcs1,Kpna3,Wdr43,Idi1,Rap2c,Tax1bp1,Mndal,Eif4g2,Xaf1,Ifi203,Pdss1,Ppp4r2,Ifi211,Mpp7,Ifi214,Coa5,Ccnd2,Palld,Vcpip1,Ifi207,Spred1,Pnpt1,Dnaja1,Ptpn2,Cyfip1,Psip1,Crbn,Samd9l,Irgm2,Serpinb9,4930453N24Rik,Fndc3a,Smc5,Tcea1,Igf2bp2,Pkp4,Inpp1,Dek,Atp6v1d,Vps54,Cacybp,Nampt,Ifi208,Hif1a,Fam133b,Mapkbp1,Ifi209,Tank,Ifi205,Rbbp8,Ifi213,Ifit2,Tlk2,Ogfrl1,Lztfl1,Nr3c1 |
| 5.918e-04 | -7.43 | GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_DN | MSigDB lists | GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_DN | 182 | 28 | 15632 | 1249 |
Il18,Pik3cd,Gpd2,Mthfd2,Rtn1,Bcl2a1a,Acsl5,Kdr,Igsf8,Inpp5b,Ampd3,Nfkbib,Evl,Psme1,Mxd1,Gnb4,Gclc,Gys1,Znfx1,Stat5a,Cnn2,Bcl2a1b,Rnf114,Il18bp,Bcl2a1d,Ctsc,Tbc1d1,Irf4 |
| 5.918e-04 | -7.43 | GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_UP | 182 | 28 | 15632 | 1249 |
Ptk2,Dyrk2,Htr2b,Sec24b,Zhx2,Bcl2a1a,Klf2,Tnfsf14,Gch1,Parp12,Isg20,Ddx58,Slc30a1,Plk3,Ddx60,Mvp,Pfkfb3,Sla,Gpr18,Mtus1,Birc2,Bcl2a1b,Acvr1,Dusp4,Dock10,Bcl2a1d,Abcb1a,Egr2 |
| 5.918e-04 | -7.43 | GSE17721_LPS_VS_CPG_24H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_24H_BMDC_UP | 182 | 28 | 15632 | 1249 |
Serpine1,Ccr1,Tdrd7,Uba7,Phyh,Slamf8,Stat1,Smox,Fam162a,P2ry12,Arid5a,Timp1,Plekhf2,Sbds,Ifit2,Dtnb,Rsad2,Gbp4,Gbp9,Gclm,Tor1aip2,Il1a,Stat2,Stxbp1,Gbp2,Gda,Il15,Crlf3 |
| 5.918e-04 | -7.43 | GSE3039_CD4_TCELL_VS_NKT_CELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_NKT_CELL_UP | 182 | 28 | 15632 | 1249 |
Il4i1,Dennd1b,Sat1,Dock4,P2ry13,B4galt4,Fbxo4,Relb,Lrp8,Evl,Pikfyve,Traf1,Rab19,Icam1,Slpi,Zeb1,Ube2e2,Rictor,Ccl5,Arid4a,Rnaset2a,Notch2,Ap3m2,Armc8,Rnaset2b,Mtmr14,Fam111a,Rnf145 |
| 5.918e-04 | -7.43 | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP | MSigDB lists | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP | 182 | 28 | 15632 | 1249 |
Ifit1bl2,Tuba4a,Hopx,Btg2,Trim26,Dgka,Zc3h12a,Trib1,Ms4a6d,Rnf145,Spata5l1,Clcf1,Chd9,Ikbke,Pkp4,Parp8,Gramd1a,Ifit1bl1,Abcb1a,Prkce,Rffl,Gbp9,Gbp4,Glipr2,Abr,Rhoh,Rnf139,Zfp281 |
| 5.918e-04 | -7.43 | GSE14350_IL2RB_KO_VS_WT_TREG_UP | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TREG_UP | 182 | 28 | 15632 | 1249 |
Psmb10,Mcoln2,Mdfic,Gbp2,Tspo,Dse,Acpp,Nlrc5,Pik3r5,Triobp,Tapbp,Irgm2,Mdn1,Ccdc86,Acvr1b,Sema4a,Stat1,Mmp9,Pim2,Glrx,Cd86,Tor1aip1,Gbp7,Dach1,Trim26,Wdfy1,Bcl9,Phlpp2 |
| 5.940e-04 | -7.43 | GSE11924_TFH_VS_TH1_CD4_TCELL_UP | MSigDB lists | GSE11924_TFH_VS_TH1_CD4_TCELL_UP | 191 | 29 | 15632 | 1249 |
Ifit3b,Lyn,Gng4,Oas1g,Fam53c,Sec24b,Igf1r,Bcl2a1a,Orai2,Osbpl3,Casp4,Ifit3,Asah2,Ppm1k,Mcm9,Arid4a,Tor3a,Oas1a,Icosl,Gbp3,Acpp,Bcl2a1b,Agrn,Crbn,Bcl2a1d,Cnot4,Setdb2,Gpr84,Tbc1d1 |
| 5.940e-04 | -7.43 | GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | 191 | 29 | 15632 | 1249 |
Osm,Tnfsf14,Itgal,Ifit1bl2,Fam72a,Rnf19a,Timeless,4930453N24Rik,Smc5,Dusp5,Atp10a,Lhx2,Tnfsf10,Arid5a,Dse,Insl6,Ifit1bl1,Spn,Klf3,Ift57,Cish,Arl4a,Arrdc4,Spata13,Ddx60,Mxd1,Tnfrsf14,Rab3ip,Ccdc88b |
| 5.940e-04 | -7.43 | GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDC_DN | 191 | 29 | 15632 | 1249 |
Map4k4,Bcl9,Uba7,Fam53c,Rtn1,Mob3b,Tnfaip2,Adam19,Tnip1,Slfn9,Ppp2r2a,Agrn,Rgs14,Oas3,Tmem184b,Hmga1,Slfn8,Pde1b,Ncoa5,B3gnt5,Hlx,Zfp281,F11r,Rnf135,Gys1,Notch1,Chmp4b,Tap1,Mdfic |
| 5.943e-04 | -7.43 | extracellular organelle | cellular component | GO:0043230 | 113 | 18 | 20747 | 1409 |
Gbp7,Gbp2b,Gbp2,Icam1,Cd86,Gbp9,Gbp3,Ppfia3,Asah2,Itga4,Irgm2,Pf4,Arrdc4,Iigp1,Gbp8,Vasn,Serpine1,Cd274 |
| 5.948e-04 | -7.43 | epithelial cell differentiation | biological process | GO:0030855 | 527 | 56 | 20694 | 1406 |
Myadm,Tagln,Flnb,Tdrd7,Ptch1,Gja1,Casp3,F11r,Spint2,Foxp4,Gfi1,Gpsm2,Notch1,Hhex,Fam20c,Palld,Ptgs2,Jag1,Pdgfb,Rilpl1,Hif1a,Rap2c,Bmp2,Map2k1,Rapgef2,Frmd6,Notch2,Col18a1,Icam1,Clic4,Fndc3a,Klf2,Triobp,Pou3f1,Sav1,Clic5,Kdm6b,Sec24b,Plod3,Slc4a7,Jun,Fzd1,Stat5a,Pdpn,Il1a,Kdr,Arid4a,Ezr,Plaur,Acvr1,Intu,Hdac1,Prdm1,Acvrl1,Myd88,Met |
| 5.953e-04 | -7.43 | GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 246 | 35 | 15632 | 1249 |
Tnfaip3,Gclc,Psmb10,Plk3,Ube2e1,Psme1,Rnf139,Mdm2,Psma6,Ctsc,Psmd10,Psmb9,Tiparp,Ezr,Tnf,Rnf114,Dnajb2,Il1b,Keap1,Trib3,Trib1,Rnf19b,Ptk2,Psmb6,Smc5,Rnf19a,Ppp2r3a,Psme2,Plk2,Cav1,Ankib1,Psmb8,Gja1,Tnfrsf1b,Rnf14 |
| 5.972e-04 | -7.42 | WH1/EVH1_dom | interpro domains | IPR000697 | 11 | 5 | 19984 | 1430 |
Vasp,Spred3,Homer1,Evl,Spred1 |
| 5.972e-04 | -7.42 | TNF_CS | interpro domains | IPR021184 | 11 | 5 | 19984 | 1430 |
Tnfsf10,Tnfsf8,Tnf,Tnfsf4,Tnfsf9 |
| 5.991e-04 | -7.42 | GSE21033_3H_VS_12H_POLYIC_STIM_DC_UP | MSigDB lists | GSE21033_3H_VS_12H_POLYIC_STIM_DC_UP | 147 | 24 | 15632 | 1249 |
Ptgir,Csrnp1,Ptprj,Arl5c,Papss2,Socs1,Slc16a1,Slc25a25,Sec24b,Angpt1,Myo10,Stau1,Ppp1r14b,Rbbp8,Gem,Tap2,Itpr1,Tifa,Phgdh,Zeb1,Egln3,B3gnt5,Nfkbie,Ccdc25 |
| 6.000e-04 | -7.42 | bZIP_1 | pfam domains | PF00170 | 28 | 8 | 18711 | 1348 |
Fosb,Batf,Jdp2,Junb,Fos,Batf2,Jun,Atf3 |
| 6.029e-04 | -7.41 | chr13q14 | MSigDB lists | chr13q14 | 66 | 14 | 15632 | 1249 |
Phf11a,Htr2a,Phf11c,Esd,Lacc1,Fndc3a,Kpna3,Trim13,Phf11d,Lrch1,Setdb2,Cysltr2,Spryd7,Phf11b |
| 6.029e-04 | -7.41 | PID_INTEGRIN1_PATHWAY | MSigDB lists | PID_INTEGRIN1_PATHWAY | 66 | 14 | 15632 | 1249 |
Tnc,Itgav,Col11a2,Igsf8,Plau,Vcam1,Cd14,Thbs1,Plaur,Itga4,Col18a1,Itga5,Tgfbi,Itga9 |
| 6.029e-04 | -7.41 | SESTO_RESPONSE_TO_UV_C8 | MSigDB lists | SESTO_RESPONSE_TO_UV_C8 | 66 | 14 | 15632 | 1249 |
Mthfd2,Il4ra,Ccnd2,Me1,Tnfsf10,Slc2a1,Serpine1,Sema3c,Cyfip1,Hk1,Slc7a5,Ppp2r5a,Flnb,Myc |
| 6.057e-04 | -7.41 | Immunoproteasome | KEGG pathways | M00337 | 18 | 7 | 7931 | 713 |
Psme1,Psmb8,Psmb10,Psmb9,Psma6,Psme2,Psme2b |
| 6.057e-04 | -7.41 | Immunoproteasome | KEGG pathways | mmu_M00337 | 18 | 7 | 7931 | 713 |
Psma6,Psme2,Psme2b,Psme1,Psmb8,Psmb10,Psmb9 |
| 6.082e-04 | -7.41 | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_2_OXOGLUTARATE_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_EACH_OF_OXYGEN_INTO_BOTH_DONORS | MSigDB lists | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_2_OXOGLUTARATE_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_EACH_OF_OXYGEN_INTO_BOTH_DONORS | 38 | 10 | 15632 | 1249 |
Kdm5b,Egln3,P4ha2,P4ha1,Plod3,Tet2,Kdm4a,Phyh,Jmjd6,Plod2 |
| 6.082e-04 | -7.41 | GO_PEPTIDYL_TYROSINE_AUTOPHOSPHORYLATION | MSigDB lists | GO_PEPTIDYL_TYROSINE_AUTOPHOSPHORYLATION | 38 | 10 | 15632 | 1249 |
Lyn,Fgr,Syk,Src,Ptk2,Hck,Tyk2,Igf1r,Kdr,Jak2 |
| 6.119e-04 | -7.40 | cellular response to hydrogen peroxide | biological process | GO:0070301 | 60 | 12 | 20694 | 1406 |
Sphk1,Bnip3,Il6,Sirt1,Src,Nqo1,Pdgfrb,Axl,Tnfaip3,Lcn2,Ripk3,Kdm6b |
| 6.120e-04 | -7.40 | MHC protein complex | cellular component | GO:0042611 | 23 | 7 | 20747 | 1409 |
H2-Q6,H2-Q7,H2-Eb1,H2-Q4,Cd74,H2-Aa,H2-Ab1 |
| 6.135e-04 | -7.40 | zinc ion homeostasis | biological process | GO:0055069 | 23 | 7 | 20694 | 1406 |
Mt2,Slc39a14,Slc39a13,Slc30a4,Mt1,Slc30a1,Slc39a4 |
| 6.135e-04 | -7.40 | positive regulation of interferon-alpha production | biological process | GO:0032727 | 23 | 7 | 20694 | 1406 |
Ddx58,Irf7,Zc3hav1,Stat1,Ifih1,Tlr9,Tlr3 |
| 6.135e-04 | -7.40 | positive regulation of protein autophosphorylation | biological process | GO:0031954 | 23 | 7 | 20694 | 1406 |
Tnks1bp1,Vegfc,Pdgfb,Syk,Src,Pdgfc,Rap2c |
| 6.135e-04 | -7.40 | negative regulation of cytokine production involved in immune response | biological process | GO:0002719 | 23 | 7 | 20694 | 1406 |
Irak3,Bcl6,Ifnb1,Il10,Tnf,Hmox1,Angpt1 |
| 6.135e-04 | -7.40 | cellular response to cadmium ion | biological process | GO:0071276 | 23 | 7 | 20694 | 1406 |
Mt1,Mmp9,Fos,Jun,Daxx,Hmox1,Mt2 |
| 6.139e-04 | -7.40 | export from cell | biological process | GO:0140352 | 446 | 49 | 20694 | 1406 |
Trem1,Plek,Hck,Stx11,Hap1,Il6,Nos2,Kcna3,Apba1,Pou2f2,Optn,Nlrp3,Notch1,Isg15,Axl,Nlrc4,Tlr6,Pdzd11,Lcp2,Rims3,Itgav,Tlr2,Nr4a3,Lyn,Inhba,Ppfia3,Milr1,Abcc1,Rasgrp1,Ccr1,Dio2,Stxbp1,Syk,Abcb1a,Mcoln2,Mecp2,Aim2,Rab11fip1,Svbp,Tnfaip2,Traf3ip2,Il1rn,Rnf19b,Stxbp3,Edn1,Rab10,Ccl5,Nod2,Notch2 |
| 6.153e-04 | -7.39 | cytoplasmic side of plasma membrane | cellular component | GO:0009898 | 162 | 23 | 20747 | 1409 |
Ezr,Gng11,Hck,Dst,Cyth3,Src,Fgr,Pkp4,Gnb4,Rgs1,Traf5,Lyn,Traf2,Gramd1a,Gng12,Birc2,Errfi1,Chmp4b,Gna15,Gng4,Gem,Rnf31,Rab21 |
| 6.160e-04 | -7.39 | WH1 | pfam domains | PF00568 | 11 | 5 | 18711 | 1348 |
Spred1,Spred3,Evl,Homer1,Vasp |
| 6.168e-04 | -7.39 | positive regulation of nuclear division | biological process | GO:0051785 | 77 | 14 | 20694 | 1406 |
Tnf,Smc5,Il1a,Rgcc,Edn1,Phip,Cenpe,Sphk1,Pdgfb,Igf1r,Il1b,Pdgfrb,Met,Prdm9 |
| 6.168e-04 | -7.39 | regulation of blood coagulation | biological process | GO:0030193 | 77 | 14 | 20694 | 1406 |
Plau,Plek,Cd34,Adrb2,Thbs1,Enpp4,Ptprj,Syk,Ubash3b,Pdgfb,Pdpn,Serpine1,Lyn,Cav1 |
| 6.170e-04 | -7.39 | TYR_PHOSPHATASE_DUAL_dom | interpro domains | IPR020422 | 35 | 9 | 19984 | 1430 |
Dusp14,Dusp1,Dusp2,Dusp6,Dusp8,Dusp16,Dusp28,Dusp4,Dusp5 |
| 6.241e-04 | -7.38 | regulation of ion transport | biological process | GO:0043269 | 732 | 73 | 20694 | 1406 |
Ccl5,Icam1,Hk1,Serpine1,Hvcn1,Irs2,Edn1,Homer1,Hspa2,Clic4,Nlgn2,Agrn,Kmo,Clic5,Il1rn,Fabp3,Pdgfrb,Pde4b,Htr2a,Cx3cl1,Tnf,P2ry2,Adora2a,Il1a,P2ry12,Tspo,Cacna1d,Cxcl1,Ccl4,Stxbp1,Abcb1a,Syk,Atp2b4,Ubash3b,Ccl12,Glrx,Pml,Ccr1,Mllt6,Gpr35,Ccl2,Slc9a1,Adrb2,Tlr9,Slc30a1,Ahr,Prkce,Slc31a2,Cav1,Lyn,Itpr1,Crbn,Gja1,Il1b,Akt3,Acsl5,Mmp9,Ptgs2,Kcna3,Cxcl10,Arg2,Ptafr,Scn1b,Pdgfb,Gem,Stoml1,Kcnj2,Hap1,Prnp,Cox17,Thbs1,Nr3c1,Cacnb3 |
| 6.252e-04 | -7.38 | - | gene3d domains | 2.170.150.30 | 3 | 3 | 8819 | 755 |
Dhx58,Ddx58,Ifih1 |
| 6.259e-04 | -7.38 | GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | 20 | 7 | 15632 | 1249 |
Plaur,Jak2,Tnfsf10,Traf2,Casp8,Fas,Mmp9 |
| 6.259e-04 | -7.38 | NOJIMA_SFRP2_TARGETS_DN | MSigDB lists | NOJIMA_SFRP2_TARGETS_DN | 20 | 7 | 15632 | 1249 |
Met,Ifnb1,Mdm2,Ccnd1,Ifi44,Stat1,Trim14 |
| 6.259e-04 | -7.38 | MURATA_VIRULENCE_OF_H_PILORI | MSigDB lists | MURATA_VIRULENCE_OF_H_PILORI | 20 | 7 | 15632 | 1249 |
Ccnd2,Bcl6,Aim2,Sod2,Mmp13,Cdkn1a,Mvp |
| 6.259e-04 | -7.38 | ZHU_SKIL_TARGETS_UP | MSigDB lists | ZHU_SKIL_TARGETS_UP | 20 | 7 | 15632 | 1249 |
Rhoq,Plau,Ccng2,Cdkn1a,Junb,Serpine1,Ppp1r15a |
| 6.259e-04 | -7.38 | NIELSEN_LEIOMYOSARCOMA_CNN1_DN | MSigDB lists | NIELSEN_LEIOMYOSARCOMA_CNN1_DN | 20 | 7 | 15632 | 1249 |
Spry2,Pdpn,Socs3,Uaca,Etv5,Plagl1,Tcf4 |
| 6.259e-04 | -7.38 | REACTOME_CTLA4_INHIBITORY_SIGNALING | MSigDB lists | REACTOME_CTLA4_INHIBITORY_SIGNALING | 20 | 7 | 15632 | 1249 |
Akt3,Cd80,Ppp2r5a,Ppp2r1b,Cd86,Lyn,Src |
| 6.261e-04 | -7.38 | GO_ENZYME_ACTIVATOR_ACTIVITY | MSigDB lists | GO_ENZYME_ACTIVATOR_ACTIVITY | 421 | 53 | 15632 | 1249 |
Mark2,Cdc42ep2,Cdk5r1,Abr,Rin2,Phactr4,Spry2,Ctsc,Tor1aip2,Prkce,Mmp14,Jun,Trip10,Dock4,Tagap,Cdkn1a,Cflar,Rgs1,Rictor,Dcp1a,Rap1gap2,Psme2,Cav1,Adap2,Daxx,Apaf1,Rgs3,Nod1,Bmp2,Ahsa1,Malt1,Psme1,Asap3,Errfi1,Arhgap26,Casp3,Tbc1d1,Dbnl,Rgs14,Casp1,Htr2b,Elmod2,Nsmaf,Cdc42ep4,Rapgef2,Tbc1d13,Pdgfb,Inpp5b,Tor1aip1,Ppp1r15a,Sipa1l1,Map2k1,Ccl5 |
| 6.274e-04 | -7.37 | glomerulus vasculature development | biological process | GO:0072012 | 17 | 6 | 20694 | 1406 |
Notch2,Pdgfb,Egr1,Pdgfrb,Notch1,Angpt1 |
| 6.274e-04 | -7.37 | regulation of phospholipid biosynthetic process | biological process | GO:0071071 | 17 | 6 | 20694 | 1406 |
Pdgfb,Htr2a,Fabp3,Pcx,Fpr2,Htr2b |
| 6.274e-04 | -7.37 | activation of NF-kappaB-inducing kinase activity | biological process | GO:0007250 | 17 | 6 | 20694 | 1406 |
Ikbkg,Tlr1,Traf2,Malt1,Tnfsf15,Irak2 |
| 6.287e-04 | -7.37 | positive regulation of response to interferon-gamma | biological process | GO:0060332 | 7 | 4 | 20694 | 1406 |
Irgm1,Nlrc5,Parp9,Irgm2 |
| 6.287e-04 | -7.37 | regulation of calcidiol 1-monooxygenase activity | biological process | GO:0060558 | 7 | 4 | 20694 | 1406 |
Gfi1,Nfkb1,Tnf,Il1b |
| 6.287e-04 | -7.37 | platelet degranulation | biological process | GO:0002576 | 7 | 4 | 20694 | 1406 |
Lyn,Syk,Stxbp1,Plek |
| 6.287e-04 | -7.37 | positive regulation of interferon-gamma-mediated signaling pathway | biological process | GO:0060335 | 7 | 4 | 20694 | 1406 |
Nlrc5,Parp9,Irgm2,Irgm1 |
| 6.287e-04 | -7.37 | nucleotide-binding oligomerization domain containing 2 signaling pathway | biological process | GO:0070431 | 7 | 4 | 20694 | 1406 |
Ripk2,Nod2,Nfkbia,Irgm2 |
| 6.287e-04 | -7.37 | regulation of phosphatidylinositol biosynthetic process | biological process | GO:0010511 | 7 | 4 | 20694 | 1406 |
Fpr2,Htr2a,Pdgfb,Htr2b |
| 6.287e-04 | -7.37 | nucleotide-binding oligomerization domain containing signaling pathway | biological process | GO:0070423 | 7 | 4 | 20694 | 1406 |
Irgm2,Nod2,Nfkbia,Ripk2 |
| 6.287e-04 | -7.37 | response to bacterial lipoprotein | biological process | GO:0032493 | 7 | 4 | 20694 | 1406 |
Tlr6,Tlr1,Tlr2,Cd14 |
| 6.287e-04 | -7.37 | protection from natural killer cell mediated cytotoxicity | biological process | GO:0042270 | 7 | 4 | 20694 | 1406 |
Tap1,Tap2,Clec2d,Serpinb9 |
| 6.287e-04 | -7.37 | positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target | biological process | GO:0002860 | 7 | 4 | 20694 | 1406 |
Nectin2,Il12b,Klrk1,Pvr |
| 6.385e-04 | -7.36 | GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11 | MSigDB lists | GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11 | 59 | 13 | 15632 | 1249 |
Hmgcs1,Agtrap,Sla,Samhd1,Dpy19l1,Hivep2,Card6,Plekha5,Rnf31,Fos,Gpsm2,Trip13,Xaf1 |
| 6.385e-04 | -7.36 | GO_POSITIVE_REGULATION_OF_JUN_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_JUN_KINASE_ACTIVITY | 59 | 13 | 15632 | 1249 |
Dbnl,Edn1,Syk,Map3k6,Tnf,Traf2,Fzd5,Il1b,Mdfic,Daxx,Tlr6,Tlr9,Mul1 |
| 6.385e-04 | -7.36 | GO_DOUBLE_STRANDED_RNA_BINDING | MSigDB lists | GO_DOUBLE_STRANDED_RNA_BINDING | 59 | 13 | 15632 | 1249 |
Stau1,Oas1g,Oasl1,Ddx60,Tlr3,Mtdh,Ifih1,Ddx58,Oas2,Dhx58,Oas1a,Eif2ak2,Oas3 |
| 6.385e-04 | -7.36 | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | 59 | 13 | 15632 | 1249 |
Prnp,Lyn,Prdm1,Tnfrsf14,Tnfaip3,Il10,Cd274,Atm,H2-Eb1,Spn,Pde5a,Casp3,Peli1 |
| 6.418e-04 | -7.35 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | 174 | 27 | 15632 | 1249 |
Traf3ip2,Nsmaf,Ttc39b,Orai2,Ttc9c,Tnfsf14,Fzd5,Ppm1k,Daam1,Gna15,Slpi,Adora2a,Leng9,Stat4,Prdm1,Nck1,Arrdc4,Gbe1,Rhoc,Mvp,Slc28a2,Slc16a3,Cnn2,Slc2a1,Dennd1b,Pde5a,Arhgap26 |
| 6.418e-04 | -7.35 | GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_DN | MSigDB lists | GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_DN | 174 | 27 | 15632 | 1249 |
Fosb,Tnfrsf1b,Psmb8,Eya4,Zfp36,Timeless,Flnb,Ext1,Sema4a,Hsd17b7,Xcr1,Csf3r,Dync1h1,Hsph1,Src,Cnn2,Gadd45g,Mmp14,Pnp2,Egr2,Sat1,Psmb10,Cd180,Prnp,Tap1,Gbp2,Stau1 |
| 6.418e-04 | -7.35 | GSE3982_EOSINOPHIL_VS_TH2_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_TH2_UP | 174 | 27 | 15632 | 1249 |
Gcnt2,Bcl2a1a,Ptges,Ppfibp2,Cd55,Ptafr,Trib1,Nmi,Cysltr2,Inpp5b,Syne2,Rabgef1,C1rl,Htr2a,Myd88,Hk3,Mthfr,Bcl2a1d,Mid1,Txnrd1,Bcl2a1b,Plekhf2,Cnn2,Parp8,Serp1,Birc2,Tpst1 |
| 6.418e-04 | -7.35 | GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_DN | MSigDB lists | GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_DN | 174 | 27 | 15632 | 1249 |
Cd200,Smc5,Phyh,Map3k8,Cxcl1,Jak2,Atm,Rel,Gem,Psme2,Flnb,Pla2g7,Cxcl2,Atf3,Rhoh,Pttg1,Traf1,Arg2,Rnd3,Pde3b,Gng11,Clcn5,Mdfic,Gbp2,Ccl12,Apobec3,B4galt4 |
| 6.418e-04 | -7.35 | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN | 174 | 27 | 15632 | 1249 |
Tpi1,Isg15,Bmp2,Tle3,Klf6,Syk,Ppp1r14b,Ctsc,Fut8,Myc,Fgl2,Ifi35,Mtmr14,Dram1,Ldha,Lox,Orai2,Rbms1,Ust,Ppfibp2,Abcc1,Pgk1,Keap1,Hk1,Ccl5,Daam1,Lmo4 |
| 6.418e-04 | -7.35 | GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP | 174 | 27 | 15632 | 1249 |
Me1,Rbms2,Nxf1,Socs1,Prnp,Kmo,Aim2,Ccnd1,Acvr1,Myc,Peli1,Irf4,Bcl2l11,Spsb1,Dcbld2,Inpp1,Cldnd1,Cd82,Gfpt1,Acvr1b,Gng4,Cd200,Smox,Ppp2r3a,Cxcl2,Gna15,Cav1 |
| 6.418e-04 | -7.35 | GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_DN | MSigDB lists | GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_DN | 174 | 27 | 15632 | 1249 |
Apobec3,Insl6,Klhl25,Nat2,Treml2,Psmb10,1600014C10Rik,Nod1,Slc28a2,Gbp2,Pde4b,Birc3,Arid4a,Tap2,Itgal,Btg2,Pou2f2,Tdrd7,Slc25a12,Oas1a,Oas1g,Casp7,Pik3cd,Rnf145,Dnajb4,Inpp1,Hcls1 |
| 6.449e-04 | -7.35 | secretion | biological process | GO:0046903 | 517 | 55 | 20694 | 1406 |
Apba1,Pou2f2,Abcc4,Optn,Isg15,Nlrp3,Notch1,Axl,Nlrc4,Gja1,Itgav,Rims3,Pdzd11,Tlr6,Lcp2,Nr4a3,Tlr2,Ccnd1,Inhba,Lyn,Cav1,Plek,Trem1,Hck,Stx11,Snx10,Hap1,Hif1a,Il6,Nos2,Svbp,Myc,Tnfaip2,Il1rn,Traf3ip2,Rnf19b,Edn1,Stxbp3,Rab10,Ccl5,Nod2,Notch2,Ppfia3,Milr1,Rasgrp1,Pla2g4a,Ccr1,Dio2,Stxbp1,Syk,Mecp2,Mcoln2,Aim2,Stat5a,Rab11fip1 |
| 6.457e-04 | -7.35 | REACTOME_GPCR_LIGAND_BINDING | MSigDB lists | REACTOME_GPCR_LIGAND_BINDING | 372 | 48 | 15632 | 1249 |
Calcrl,Ccl3,Gnb4,P2ry12,P2ry13,Gpr68,Adora2b,Cxcl10,Fpr1,Ptafr,Ptger4,Cd55,Gng4,Gng12,Htr2b,Hcar2,Pf4,Cxcl1,Fzd5,Ccr1,Ccl5,Adora2a,Cxcl2,Fzd1,Gpr132,Fpr2,Ccl22,Cx3cl1,P2ry14,Htr2a,Gng11,Gpr18,Cx3cr1,Ccl12,S1pr2,Edn1,Ccr3,Prokr1,Lpar1,Adrb2,C3,Ptgir,Xcr1,Ccl4,Ptch1,P2ry2,Ednrb,Cysltr2 |
| 6.467e-04 | -7.34 | GSE10273_LOW_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN | MSigDB lists | GSE10273_LOW_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN | 183 | 28 | 15632 | 1249 |
Bcl2a1d,Nfkbie,Cept1,Slc39a4,Gbp9,Gbp4,Ttc39c,Bcl2a1b,Flt1,Nr4a1,Hck,Vcpip1,Adar,Zfp281,Vasp,Uba7,Pdlim7,Psme2,Gpr132,Nos2,Ikbkg,Ttc9c,Plaur,Slc37a3,Hcls1,Bcl2a1a,Parp3,Mmp9 |
| 6.467e-04 | -7.34 | GSE3982_EOSINOPHIL_VS_BCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_BCELL_DN | 183 | 28 | 15632 | 1249 |
Ifi207,Dusp14,Mapkbp1,Ifi214,Psme1,Dhx58,Irf4,Pnp2,Ifi209,Ifi205,Ifi213,Il15ra,Osbpl3,Clic4,Ifi204,Kcna3,Serpinb9,Casp7,Traf3ip2,Ifi203,Ifi211,Ifi208,Asns,Hopx,Rrs1,Mndal,Golga3,Ccne1 |
| 6.467e-04 | -7.34 | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_UP | 183 | 28 | 15632 | 1249 |
Cd164,Mdfic,Rhoc,Plagl1,Traf1,Aldh1b1,Dmxl2,Slc30a1,Arl4a,Stat3,Igsf6,Ppp2r5a,Ehd1,Ccl12,Glrx,Tfec,Ppp2r2a,Serpinb2,Kcna3,Ldha,Ell2,Usp12,Cxcl2,Ube2l6,Trip13,Sema3c,Serpine1,Txn1 |
| 6.467e-04 | -7.34 | GSE23502_BM_VS_COLON_TUMOR_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_DN | MSigDB lists | GSE23502_BM_VS_COLON_TUMOR_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_DN | 183 | 28 | 15632 | 1249 |
Pim2,Traf3ip2,Endod1,Acvr1b,Ldlr,Whamm,Cxcl1,Pkp4,Myadm,Atm,Vezt,Slc2a6,Btg2,Gpr132,Spen,Syne2,Nupr1,Ier2,Itga4,Abr,Ccnd2,Ncoa7,Pik3r5,Rab32,Klf3,Rhbdf2,Rab11fip1,Phlpp1 |
| 6.467e-04 | -7.34 | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | 183 | 28 | 15632 | 1249 |
Ogfr,Psmb8,Txn1,Tyk2,Degs2,Phlda1,Ptafr,Kif3c,Odc1,Tgfbi,Rnf145,Fndc3a,Casp7,Rnf19b,Xcr1,Keap1,Pfkl,Adam19,Psmb9,Sod2,Mdm2,Pde1b,Psmb10,Nek6,Psme1,Ube2e1,Gclc,Il15 |
| 6.467e-04 | -7.34 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN | 183 | 28 | 15632 | 1249 |
Tnfrsf1b,Parp12,Oas1a,Phlpp2,Ttc39b,Acvr1b,Oas1g,Fndc3a,Rac3,Max,Zcchc2,Cd40,Tiparp,Klhl25,B4galt4,Itpr1,Aoah,Hivep2,Spsb1,Cpd,Cers6,Fchsd2,1110038F14Rik,Prnp,Ahr,Olfml3,Mdfic,Rab3ip |
| 6.467e-04 | -7.34 | GSE26488_CTRL_VS_PEPTIDE_INJECTION_HDAC7_DELTAP_TG_OT2_THYMOCYTE_DN | MSigDB lists | GSE26488_CTRL_VS_PEPTIDE_INJECTION_HDAC7_DELTAP_TG_OT2_THYMOCYTE_DN | 183 | 28 | 15632 | 1249 |
Tiparp,Mrpl52,Ppp1r14b,Sele,Mafk,Errfi1,Irs2,Gbp3,Ciapin1,Hck,Rgs3,Adar,Gys1,Rbms2,Myd88,Fosb,Gem,Plk2,Atm,Ampd3,Zfp36,Btg2,Rcn1,Stat1,Il13ra1,Ptk2,Tnfsf10,Ralgds |
| 6.467e-04 | -7.34 | GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN | MSigDB lists | GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN | 183 | 28 | 15632 | 1249 |
Il1a,Sell,Olr1,Slc25a25,Cd14,Tspo,Mtus1,Eno1,Gadd45b,Plod3,Tagln,S1pr2,Fgl2,Phgdh,Fcgr2b,Igsf6,Arid5b,Hp,Trem1,Pgk1,Glrx,Irf8,Lcn2,Tor3a,Ccr1,Pou2f2,Egln3,Alas1 |
| 6.467e-04 | -7.34 | GSE5503_LIVER_DC_VS_MLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | MSigDB lists | GSE5503_LIVER_DC_VS_MLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | 183 | 28 | 15632 | 1249 |
Ifit3b,Rcsd1,Slfn9,Ifit3,Marco,Cnp,Psd4,Tnfrsf1b,Stx6,Stat4,Ociad1,Nxf1,Ddx58,Usp18,Rhoh,Psme1,Nck1,Cd38,Rras2,Trmt1l,Rnf114,Cnn2,Nfkbie,Aebp2,Sat1,Slfn8,Abcb1a,D1Ertd622e |
| 6.476e-04 | -7.34 | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN | MSigDB lists | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN | 192 | 29 | 15632 | 1249 |
Ubash3b,Plagl1,Fam133b,Arrdc4,Gbp3,Bmp2,Chmp4b,Mdfic,Ehd1,Axl,N4bp1,Slc39a4,Fgl2,Ptprj,Rnf19b,Kif5c,Osbpl3,Chd9,Ppp2r1b,Il15ra,Ppp2r2a,Prkar2b,Gch1,Ahrr,Plekha2,Csf1,Pstpip2,Ppp4r2,Bst1 |
| 6.513e-04 | -7.34 | BROWNE_HCMV_INFECTION_2HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_2HR_DN | 45 | 11 | 15632 | 1249 |
Cdc42ep2,Abcc1,Stip1,Plaur,Phlda1,Myc,Dusp6,Ifit2,Axl,Cenpe,Serpine1 |
| 6.513e-04 | -7.34 | KEGG_TYPE_II_DIABETES_MELLITUS | MSigDB lists | KEGG_TYPE_II_DIABETES_MELLITUS | 45 | 11 | 15632 | 1249 |
Socs1,Irs2,Pik3cd,Socs3,Hk1,Pik3r5,Tnf,Hk2,Hk3,Prkce,Cacna1d |
| 6.548e-04 | -7.33 | negative regulation of transmembrane transport | biological process | GO:0034763 | 133 | 20 | 20694 | 1406 |
Crbn,Stxbp3,Rhoq,Cav1,Irs2,Ahr,Tnf,Prkce,Thbs1,Myc,Slc30a1,Tlr9,Cacnb3,Gpr35,Mmp9,Stoml1,Pid1,Agrn,Il1b,Gem |
| 6.575e-04 | -7.33 | GO_GLUCOSE_METABOLIC_PROCESS | MSigDB lists | GO_GLUCOSE_METABOLIC_PROCESS | 114 | 20 | 15632 | 1249 |
Pcx,Hk2,Slc25a12,Oas1a,Hk1,Pdk3,Eno2,Tnf,Eno1,Serp1,Pfkfb3,Pgk1,Pfkl,Hk3,Tpi1,Oas1g,Atf3,Gpd2,Irs2,Pgm1 |
| 6.578e-04 | -7.33 | GO_REGULATION_OF_LIPID_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_LIPID_KINASE_ACTIVITY | 52 | 12 | 15632 | 1249 |
Src,Flt1,Ptk2,Pik3r5,Lyn,Pik3r6,Pdgfrb,Fgr,Pdgfb,Ppp2r5a,Nod2,Rbl1 |
| 6.578e-04 | -7.33 | SESTO_RESPONSE_TO_UV_C2 | MSigDB lists | SESTO_RESPONSE_TO_UV_C2 | 52 | 12 | 15632 | 1249 |
Trip10,Morc3,Dusp4,Oas1a,Jag1,Stxbp3,Plscr1,Nr3c1,Hif1a,Oas1g,Ell2,Gclc |
| 6.581e-04 | -7.33 | positive regulation of cyclin-dependent protein kinase activity | biological process | GO:1904031 | 37 | 9 | 20694 | 1406 |
Ccnd2,Src,Pdgfb,Ccnd1,Pim1,Cdk5r1,Psmd10,Rgcc,Cdkn1a |
| 6.621e-04 | -7.32 | AMIT_EGF_RESPONSE_480_HELA | MSigDB lists | AMIT_EGF_RESPONSE_480_HELA | 148 | 24 | 15632 | 1249 |
Vasp,Ext1,Isg20,Pdlim7,Serpine1,Cdyl,Brd2,Plaur,Pmepa1,Inpp1,Nfkb2,Itga5,Ccnd1,Chst11,Dusp4,Hmga1,Zyx,Slc25a37,Ehd1,Agrn,Rhoc,Plau,Col4a2,Sphk1 |
| 6.621e-04 | -7.32 | GO_PHAGOCYTOSIS | MSigDB lists | GO_PHAGOCYTOSIS | 148 | 24 | 15632 | 1249 |
Prkce,Axl,Src,Syk,Itgav,Cyfip1,Cd302,Cd14,Fcgr1,Hck,Myo10,Nck1,Jmjd6,Fgr,Nr1h3,Adora2a,Irf8,Marco,Actb,Thbs1,Ptk2,Xkr8,Rab20,Lyn |
| 6.650e-04 | -7.32 | regulation of G1/S transition of mitotic cell cycle | biological process | GO:2000045 | 114 | 18 | 20694 | 1406 |
Ccl12,Cdkn1a,Ccne1,Casp2,Pml,Psme1,Mdm2,Plk3,Pdpn,Ccnd1,Slfn1,Rgcc,Psme2,Ccnd2,Ankrd17,Ube2e2,Rbl1,Dcun1d3 |
| 6.668e-04 | -7.31 | Ig_V-set | interpro domains | IPR013106 | 184 | 26 | 19984 | 1430 |
Cd200r4,Cd274,Pvr,Cd300lf,Nectin4,Cd83,Cd300e,Clmp,A530064D06Rik,Cd200,F11r,Scn1b,B430306N03Rik,Slamf9,Cd86,Treml4,Cd80,Trem1,Tapbpl,Igsf8,Nectin2,Vcan,Treml2,Gm5150,Icosl,Siglece |
| 6.692e-04 | -7.31 | viral process | biological process | GO:0016032 | 143 | 21 | 20694 | 1406 |
Tnfrsf14,Pcx,Cav1,Icam1,Ripk3,Zbp1,Itgav,Vcam1,Pvr,Denr,Cd55,Pml,Axl,Chmp4b,Nectin2,Myc,Cd300lf,Clec5a,Nectin4,Mmp9,Bcl2l11 |
| 6.693e-04 | -7.31 | NAKAMURA_ADIPOGENESIS_LATE_DN | MSigDB lists | NAKAMURA_ADIPOGENESIS_LATE_DN | 32 | 9 | 15632 | 1249 |
Il6,Rai14,Slc7a5,Hck,Itgav,Gdf15,Ier2,Serpine1,Lox |
| 6.693e-04 | -7.31 | GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | MSigDB lists | GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | 32 | 9 | 15632 | 1249 |
Tnfsf4,Ptger4,Sema4a,Il12b,Irf4,Batf,Il6,Relb,Rsad2 |
| 6.693e-04 | -7.31 | BIOCARTA_PDGF_PATHWAY | MSigDB lists | BIOCARTA_PDGF_PATHWAY | 32 | 9 | 15632 | 1249 |
Stat1,Stat5a,Stat3,Map2k4,Jun,Map2k1,Stat2,Fos,Stat4 |
| 6.742e-04 | -7.30 | GRESHOCK_CANCER_COPY_NUMBER_UP | MSigDB lists | GRESHOCK_CANCER_COPY_NUMBER_UP | 295 | 40 | 15632 | 1249 |
Klf6,Syk,Psip1,Sbds,Hmga1,Bcl6,Irf4,Fcgr2b,Ikzf1,Myc,Ccnd1,Arhgap26,Mllt6,Malt1,Fas,Rhoh,Pml,Ccnd2,Ciita,Tal2,Pbx1,Notch1,Aff1,Atm,Birc3,Rel,Pdgfrb,Pdgfb,Bcl9,Ext1,Etv6,Met,Pim1,Chic2,Nr4a3,Map2k4,Dek,Jak2,Nfkb2,Tcea1 |
| 6.756e-04 | -7.30 | positive regulation of natural killer cell activation | biological process | GO:0032816 | 30 | 8 | 20694 | 1406 |
Il15,Rasgrp1,Il12b,Stat5a,Axl,Il15ra,Il18,Irf1 |
| 6.762e-04 | -7.30 | KOBAYASHI_EGFR_SIGNALING_24HR_UP | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_24HR_UP | 82 | 16 | 15632 | 1249 |
Cebpd,Syne2,Cpd,Ccng2,Peli1,Fzd5,Irf7,Bcl6,Ass1,Pbx1,Cd74,Acsl1,Psmb10,Dram1,Nupr1,Hmox1 |
| 6.763e-04 | -7.30 | lipopeptide binding | molecular function | GO:0071723 | 7 | 4 | 20217 | 1400 |
Tlr2,Tlr6,Tlr1,Cd14 |
| 6.772e-04 | -7.30 | cysteine-type peptidase activity | molecular function | GO:0008234 | 170 | 24 | 20217 | 1400 |
Tank,Usp31,Otud1,Usp25,Vcpip1,Usp18,Casp3,Tnfaip3,Usp53,Malt1,Casp8,Ctsc,Casp1,Uchl1,Casp7,Casp2,Usp42,Casp4,Usp12,Zc3h12a,Cflar,Zup1,Adgb,Usp35 |
| 6.837e-04 | -7.29 | SRF_Q6 | MSigDB lists | SRF_Q6 | 220 | 32 | 15632 | 1249 |
Dusp5,Ldha,Egr3,Thbs1,Pcdh7,Actb,Myadm,Dcun1d3,Junb,Ptch1,Fosb,Pdlim7,Zeb1,Ppp2r3a,Hivep3,G3bp2,Mapkapk2,Zfp513,Egr1,Abr,Prdm1,Cx3cl1,Tle3,Tagln,Nr4a1,Cnn2,Klf6,Cited2,Fos,Dusp2,Egr2,Gadd45g |
| 6.845e-04 | -7.29 | positive regulation of GTPase activity | biological process | GO:0043547 | 368 | 42 | 20694 | 1406 |
Ccl3,Ccl7,Cx3cl1,Abr,Arhgap26,Jun,Ccl4,Ric1,Dock10,Rgs3,Map2k1,Ccl12,Rasgrp1,Cdc42ep2,Ccl2,Rapgef2,Map4k4,Icam1,Dock4,Pkp4,Dennd1b,Tagap,Ccl5,Adap2,Elmod2,Asap3,Sipa1l1,F11r,Htr2b,Cd40,Crkl,Tbc1d13,Rap1gap2,Rin2,Ccl9,Ranbp2,Agrn,Rgs1,Rgs14,Ccl22,Tbc1d1,Ccl8 |
| 6.849e-04 | -7.29 | GO_REGULATION_OF_HEAT_GENERATION | MSigDB lists | GO_REGULATION_OF_HEAT_GENERATION | 15 | 6 | 15632 | 1249 |
Ccl5,Ednrb,Tnf,Pla2g4a,Il1b,Ptgs2 |
| 6.849e-04 | -7.29 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | MSigDB lists | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | 15 | 6 | 15632 | 1249 |
Adora2a,P2ry14,P2ry13,P2ry2,Adora2b,P2ry12 |
| 6.849e-04 | -7.29 | GO_REGULATION_OF_INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS | 15 | 6 | 15632 | 1249 |
Ebi3,Tlr3,Tlr9,Il27,Il12b,Inhba |
| 6.849e-04 | -7.29 | GO_REGULATION_OF_LYMPHOCYTE_CHEMOTAXIS | MSigDB lists | GO_REGULATION_OF_LYMPHOCYTE_CHEMOTAXIS | 15 | 6 | 15632 | 1249 |
Ccl4,Cxcl14,Ccl5,Ccl12,Tnfsf14,Cxcl10 |
| 6.849e-04 | -7.29 | MODULE_444 | MSigDB lists | MODULE_444 | 15 | 6 | 15632 | 1249 |
Tgfbi,Il18,Tnfaip2,Kdr,Jag1,Angpt1 |
| 6.854e-04 | -7.29 | GO_PROTEOLYSIS | MSigDB lists | GO_PROTEOLYSIS | 1076 | 115 | 15632 | 1249 |
Zc3h12a,Uchl1,Rnf19b,Usp31,Herc6,Tnfsf10,Gca,Tnfsf15,Ifi208,Ube2l6,Uba7,Pml,Malt1,Psme1,Ube2e1,Isg15,Bfar,Nod1,Casp1,Ifi213,Ifi205,Birc2,Otud1,Psmb9,Klhl25,Rffl,Casp3,C1ra,Psma6,Mdm2,Casp7,Tnip1,Cflar,Tmem67,Lnpep,Psmb8,Ankib1,C1rl,Ptch1,Casp4,Ubr4,Htra1,Casp2,Ifi203,Sirt1,Rnf19a,Lrp8,Nlrp3,Pttg1,Trim13,Fbxo4,Plau,Herc3,Vcpip1,Chmp4b,Bcl2l11,Psmd10,Psmb6,Hp,Usp42,Plat,Keap1,Map2k1,Usp35,Mmp13,Rnf139,Psmb10,Usp18,Rnf34,Tnfaip3,Apaf1,Usp53,Tnf,Rhbdf2,Ifi209,Traf2,Rnf24,Cycs,Fgl2,C3,Mmp9,Map2k4,Mmp25,Rnf145,Ifi204,Adam19,Znrf1,Jak2,Dnajb2,Fam162a,Rnf14,Nfkb1,S100a8,Casp8,Lap3,Mndal,Psme2,Ifi211,Egln3,Usp12,Usp25,Fas,Znrf3,Ifi214,Mul1,F10,Olr1,Ifi207,Sqstm1,Crbn,Nlrc4,Mmp14,Ctsc,Ift57,Cpd |
| 6.880e-04 | -7.28 | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP | MSigDB lists | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP | 26 | 8 | 15632 | 1249 |
Irf7,Pim2,Gja1,Ass1,Stat1,Ifit1bl1,Ifit1bl2,C1ra |
| 6.880e-04 | -7.28 | GROSS_ELK3_TARGETS_UP | MSigDB lists | GROSS_ELK3_TARGETS_UP | 26 | 8 | 15632 | 1249 |
Cnn2,Ass1,Cav1,Rras2,Edn1,Ccnd1,Cpd,Hck |
| 6.880e-04 | -7.28 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP | 90 | 17 | 15632 | 1249 |
Egr3,Il13ra1,Tgfbi,Fabp3,Cd34,Gca,Glrx,Ifit1bl1,Ifit1bl2,Flrt3,Ccl5,Myo1b,Fos,Hspa1a,Procr,Cp,Kctd12 |
| 6.912e-04 | -7.28 | GO_ENDOCYTIC_VESICLE | MSigDB lists | GO_ENDOCYTIC_VESICLE | 248 | 35 | 15632 | 1249 |
Marco,Fzd5,Cav1,Ptch1,H2-Eb1,Rapgef2,Stx6,Inpp5b,Rab10,Tlr1,H2-Aa,Lpar1,Rab20,Tlr2,H2-Ab1,Tlr9,Hp,Ldlr,H2-Q6,Msr1,Rab32,H2-Q4,Hsph1,Ccl12,Syk,Itgav,Mdm2,Scarf1,Irgm2,Rab9,Rab11fip1,Cd74,H2-Q7,Tlr6,Fcgr1 |
| 6.974e-04 | -7.27 | cellular response to hormone stimulus | biological process | GO:0032870 | 437 | 48 | 20694 | 1406 |
Sirt1,Il18,Pid1,Akt3,Trib3,Notch1,Crkl,Jak2,Acod1,Stat1,Nfkb1,Cav1,Inhba,Prkce,Cdk5r1,Nr4a3,Nr3c1,Src,Stat3,Cyfip1,Acsl1,Zfp36,Junb,Ptpn2,Ptk2,Nr1h3,Dnaja1,Igf1r,Socs7,Rhoq,Phip,Ifnb1,Irs2,Kat2b,Rab10,Slc9a1,Irf1,Agtrap,Glrx,Tnfsf4,Nr4a1,Ddit4,Ptger4,Atp2b4,Pde3b,Stat5a,Jun,Daxx |
| 7.002e-04 | -7.26 | TATTATA_MIR374 | MSigDB lists | TATTATA_MIR374 | 267 | 37 | 15632 | 1249 |
Il15ra,Pmepa1,Dr1,Ust,Ralgds,Map2k4,Nr4a3,Larp1,Cpeb4,Pde7b,Etv6,Rab10,Med13,Il10,Fosb,Pde4b,Dach1,Eif4g2,Dusp6,Etv5,Aff1,Crim1,Bmp2,Pikfyve,Prdm1,Abr,Nfkbiz,Mecp2,Nr3c1,Spry2,Peli1,Mmp14,Dusp8,Homer1,Hivep2,Parp8,Ppp6r1 |
| 7.022e-04 | -7.26 | Antigen Presentation: Folding, assembly and peptide loading of class I MHC | REACTOME pathways | R-MMU-983170 | 48 | 12 | 8608 | 757 |
H2-M2,Tap1,H2-T10,H2-Q4,H2-T22,Sec24b,Tap2,Tapbp,H2-Q7,H2-Q6,Sec24a,H2-T24 |
| 7.025e-04 | -7.26 | TGFB_UP.V1_DN | MSigDB lists | TGFB_UP.V1_DN | 175 | 27 | 15632 | 1249 |
Kitl,Cxcl1,Ifit3b,Adrb2,Arid5b,Irf1,Ptger4,Eya4,Sap30,Ptch1,Ifit3,Gch1,Dusp6,Rgl1,Ifit1bl2,Birc3,Sav1,Mapkbp1,Slc30a1,Ddx58,Dusp4,Spry2,Minpp1,Cited2,Bcl6,Ifit2,Ifit1bl1 |
| 7.025e-04 | -7.26 | GSE28449_WT_VS_LRF_KO_GERMINAL_CENTER_BCELL_UP | MSigDB lists | GSE28449_WT_VS_LRF_KO_GERMINAL_CENTER_BCELL_UP | 175 | 27 | 15632 | 1249 |
Nr3c1,Spry2,Pnp2,Vcan,P4ha2,Nr4a1,Acpp,Dock4,Rnd3,Pfkfb3,Olr1,Tle3,Irak3,Dmxl2,Ddit4,Bst1,Fzd1,Ccr1,Rgl1,Tnfrsf1b,Lcn2,Tlr3,Ell2,Kcna3,Nr4a3,Map3k8,Serpinb9 |
| 7.025e-04 | -7.26 | GSE15215_CD2_POS_VS_NEG_PDC_DN | MSigDB lists | GSE15215_CD2_POS_VS_NEG_PDC_DN | 175 | 27 | 15632 | 1249 |
Dcp1a,Ube2l6,Nmi,Irf7,Cdyl,Nfkb1,Gfi1,Rbms1,Idi1,Tax1bp1,Dnajb4,Odc1,Psma6,Stat3,Aftph,Ppp2r5a,Traf2,D16Ertd472e,Eno1,Gadd45b,Etv3,Pikfyve,Sertad3,Mul1,Rars,Nck1,Rnf139 |
| 7.025e-04 | -7.26 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN | 175 | 27 | 15632 | 1249 |
Vegfc,Tapbpl,Mppe1,Pim2,Egr3,Fam53c,Dgka,Vasp,Cxcl2,Stx11,St3gal5,Isg20,Cep350,Lcp2,Tnfsf14,Ppp1r15a,Tuba4a,Tnfaip3,Cd38,Kat2b,Egr1,Pgs1,Ier2,Dusp2,Spry2,Bcl6,Hivep2 |
| 7.025e-04 | -7.26 | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN | 175 | 27 | 15632 | 1249 |
Sesn3,Lnpep,Junb,Itgal,Trim26,Rasgrp1,Filip1l,Endod1,Arid5b,Acsl1,Cdc42ep4,Mafg,Azi2,Ralgds,Cd300lf,Syk,Dync1h1,Cyfip1,Swap70,Dennd1b,D1Ertd622e,Nr3c1,Tlr6,Nxf1,Calcrl,Spata13,Klf7 |
| 7.025e-04 | -7.26 | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN | MSigDB lists | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN | 175 | 27 | 15632 | 1249 |
Mdn1,Irgq,Phgdh,Stap1,Ehd1,Ezr,Syk,Cd40,Slc2a1,Rbm43,Cd164,Hhex,Nck1,Wars,Stoml1,Stat4,Pou2f2,Psd4,Hopx,Vps54,Map2k1,Plcl2,Sp110,5430427O19Rik,Cd200,Kcna3,Rcsd1 |
| 7.030e-04 | -7.26 | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | 344 | 45 | 15632 | 1249 |
Sec24a,Clic4,Nfkb2,Mcm6,Il2rg,Slc43a3,Hmox1,Vasn,Nrp2,Pdgfrb,Rgl1,Sell,Fabp3,Spata13,Nupr1,Ier2,Cish,Tnc,Mgat1,Apobec3,Adam19,Hcls1,Mthfd2,Acsl1,Filip1l,Dyrk2,Hmgcs1,Trip13,Alas1,Gem,Ccne1,Eno2,Birc3,Rbl1,Cd80,Col4a2,Pttg1,Col18a1,Cox17,Ccl2,Rai14,Peli1,Nr4a1,Plac8,Cenpe |
| 7.030e-04 | -7.26 | SANSOM_APC_TARGETS_DN | MSigDB lists | SANSOM_APC_TARGETS_DN | 344 | 45 | 15632 | 1249 |
Upp1,Arg2,1600014C10Rik,Tsku,Gbp2,Rhoc,Lipe,Casp1,Cst7,Cd302,Casp3,Ly75,Adora2b,Tgfbi,Grina,Il18,Ikbke,Keap1,Slc7a8,Ccl5,Il12rb1,Dgka,Fas,Abr,Cdkn2d,Col18a1,Nkiras1,Cx3cl1,Papss2,Nr1h3,Irf4,Cxcl14,Pcx,Casp7,Irf1,Pik3cd,Jak2,Cd82,Adam19,Mov10,Itgal,Ksr1,Srxn1,Fabp7,Slpi |
| 7.053e-04 | -7.26 | GSE339_CD4POS_VS_CD8POS_DC_UP | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_UP | 193 | 29 | 15632 | 1249 |
Relb,Samhd1,Cd164,Rgs3,Tlr6,Rhoh,Traf1,Fgr,Usp18,Abcb1a,Aebp2,Kdm5b,Nr4a1,Cyfip1,Rgs14,Arhgef3,Ccl4,Acp2,Etnk1,Il2rg,Ptgs2,Ccrl2,Nfkb1,Tnfrsf1b,Rgl1,Hdc,Map2k1,Myo1b,Lcp2 |
| 7.053e-04 | -7.26 | REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION | MSigDB lists | REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION | 193 | 29 | 15632 | 1249 |
Gng11,Gnb4,Prkce,Pla2g4a,Pik3r5,Syk,Src,Timp1,P2ry12,Thbs1,Pf4,Abcc4,Vegfc,Gng12,Gng4,Dgkh,Ptk2,Lyn,Stxbp3,Akt3,Pdgfb,Rasgrp1,Dgka,Tuba4a,Plek,Pik3r6,Serpine1,Gna15,Lcp2 |
| 7.055e-04 | -7.26 | regulation of hemostasis | biological process | GO:1900046 | 78 | 14 | 20694 | 1406 |
Plek,Plau,Thbs1,Adrb2,Cd34,Ptprj,Enpp4,Syk,Pdgfb,Ubash3b,Pdpn,Serpine1,Lyn,Cav1 |
| 7.056e-04 | -7.26 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | 140 | 23 | 15632 | 1249 |
Abcb1a,D1Ertd622e,Slc39a4,Ccnd1,Abcc5,Tagln,Cd40,Pfkfb3,Cd14,Rhoc,Atf3,Upp1,Pgm1,Pttg1,Btg2,Smpdl3b,Map4k4,Myadm,Dusp6,Fscn1,Il1rn,Trib3,Ier3 |
| 7.060e-04 | -7.26 | GSE22886_DC_VS_MONOCYTE_UP | MSigDB lists | GSE22886_DC_VS_MONOCYTE_UP | 184 | 28 | 15632 | 1249 |
Mcm6,Slamf8,Dnajb4,Filip1l,Ap3m2,Fam162a,Stard7,Zcchc2,Cacybp,Ccne1,Spint2,Jag1,Fabp3,Ccl22,Abr,Ch25h,Evl,Me1,Slc16a1,Slc48a1,Plau,Swap70,Homer1,Sdc2,Ccl2,Dennd1b,Ctsc,Micall2 |
| 7.060e-04 | -7.26 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP | 184 | 28 | 15632 | 1249 |
Rnaset2b,Pkp4,Htr2b,Bcl2a1a,Slamf8,Slamf9,Pde7b,St3gal5,Alas1,Asah2,Samsn1,Rnaset2a,Clec4n,Hk3,Cd14,Bmp2,Cd74,Bcl2a1d,Cpd,Ccr3,Fcgr2b,1110038F14Rik,Fchsd2,Cish,Mtus1,Cx3cr1,Bcl2a1b,Cst7 |
| 7.060e-04 | -7.26 | GSE19923_WT_VS_HEB_KO_DP_THYMOCYTE_UP | MSigDB lists | GSE19923_WT_VS_HEB_KO_DP_THYMOCYTE_UP | 184 | 28 | 15632 | 1249 |
Itgav,N4bp1,Nfkbia,Spsb1,Lipe,Ccl2,Irgm2,Ifih1,Sdc1,Pttg1,Plk3,Tap1,Mdfic,Ahr,Ifit1,Il15,Cd34,Col11a2,Adora2a,Degs2,Mcm6,Lpar1,Cd200,Socs3,Ptprj,Adam19,Nfkb2,Znrf1 |
| 7.060e-04 | -7.26 | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | 184 | 28 | 15632 | 1249 |
Itpr1,Dennd1b,Abcb1a,Mid1,Dusp4,Samd9l,Dock10,Cox17,Itga4,Plagl1,Cd83,Ncoa7,Dcun1d3,Lad1,H2-Aa,Phlda1,Tlr1,Ell2,Dusp5,Hmgcs1,Ptger4,Usp31,Rcsd1,Map3k8,Fam111a,Idi1,Actb,Hsd17b7 |
| 7.060e-04 | -7.26 | GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN | MSigDB lists | GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN | 184 | 28 | 15632 | 1249 |
Irf7,Nos2,Tmem176a,Csf3,Sap30,Kcna3,Odc1,Rtn1,Ell2,Dck,Rnf19b,Ikbke,Tagln,Aoah,Lipe,Tapbp,Ppp2r5a,Rab21,Ikzf1,Xrn1,Upp1,Evl,Ier2,Rbl1,Dnase1l3,Fcgr1,Cd80,Pim3 |
| 7.070e-04 | -7.25 | GO_ANTIGEN_BINDING | MSigDB lists | GO_ANTIGEN_BINDING | 67 | 14 | 15632 | 1249 |
Slc7a8,H2-Eb1,H2-Q4,Cd40,H2-Q6,H2-Aa,Ep400,Slc7a5,Tapbp,Itga4,H2-Ab1,H2-Q7,Cd74,Tap1 |
| 7.070e-04 | -7.25 | DUAN_PRDM5_TARGETS | MSigDB lists | DUAN_PRDM5_TARGETS | 67 | 14 | 15632 | 1249 |
Ets2,Gadd45b,Nlrc5,Eno2,Apobec3,Myc,Cdc42ep4,Evl,Socs3,Pml,Ncoa7,Notch1,Notch2,Myd88 |
| 7.070e-04 | -7.25 | BRUECKNER_TARGETS_OF_MIRLET7A3_DN | MSigDB lists | BRUECKNER_TARGETS_OF_MIRLET7A3_DN | 67 | 14 | 15632 | 1249 |
Dio2,Pmepa1,Ptges,Col4a2,Bcl2a1a,Gpc1,Plk2,Eif4g2,Bcl2a1b,Rin2,Bcl2a1d,Cxcl2,Nrp2,Flnb |
| 7.070e-04 | -7.25 | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | MSigDB lists | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | 67 | 14 | 15632 | 1249 |
Bcl2a1b,Slc4a7,Plod2,Tspan3,Isg20,B3gnt5,Met,Hk2,Bcl2a1d,Itga5,Bcl2a1a,Ptges,Plaur,Igf2bp2 |
| 7.073e-04 | -7.25 | GO_NEGATIVE_REGULATION_OF_HEMOPOIESIS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_HEMOPOIESIS | 123 | 21 | 15632 | 1249 |
Tmem176b,Hlx,Tlr3,Tnfsf4,Il4ra,Lyn,Trib1,Cd74,Irf1,Ubash3b,Pf4,Notch1,Nfkbia,Ptpn2,Bcl6,Myc,Ifnb1,Tmem176a,Gpr68,Nfkbid,Inhba |
| 7.073e-04 | -7.25 | RB_P130_DN.V1_DN | MSigDB lists | RB_P130_DN.V1_DN | 123 | 21 | 15632 | 1249 |
Morc3,Rnaset2a,Hspa1a,Slc2a1,Bnip3,Ctsc,Htra1,Snx2,Kdm5b,Parp9,Hk2,Stat1,Usp18,Rcn1,Asb13,Arrdc4,Rap2c,Tmem123,Idi1,Rnaset2b,Olr1 |
| 7.079e-04 | -7.25 | Antiviral mechanism by IFN-stimulated genes | REACTOME pathways | R-MMU-1169410 | 24 | 8 | 8608 | 757 |
Isg15,Ube2e1,Usp18,Flnb,Uba7,Stat1,Ube2l6,Eif4g2 |
| 7.079e-04 | -7.25 | ISG15 antiviral mechanism | REACTOME pathways | R-MMU-1169408 | 24 | 8 | 8608 | 757 |
Isg15,Usp18,Ube2e1,Uba7,Flnb,Stat1,Ube2l6,Eif4g2 |
| 7.099e-04 | -7.25 | peptide binding | molecular function | GO:0042277 | 296 | 36 | 20217 | 1400 |
Fpr2,Cd74,Lnpep,Lrp8,Cd14,Igf1r,H2-Q6,Fcgr2b,Nfkbia,Ptges,Gsr,H2-Ab1,H2-T24,Tap1,H2-Q7,H2-Q4,Adrb2,Nod2,Tlr6,Tlr2,Fzd5,Tlr1,Tap2,Marco,Ednrb,H2-M2,Gsap,Prnp,Ldlr,Apba1,Inhba,H2-T10,H2-Aa,Msr1,H2-T22,Calcrl |
| 7.122e-04 | -7.25 | supramolecular fiber organization | biological process | GO:0097435 | 449 | 49 | 20694 | 1406 |
Rnd3,Spire1,Ripk3,Cav1,Rhof,Dbnl,Rhoh,Diaph2,Swap70,Mdm2,Csrp1,Lox,Tmod3,Vasp,Cflar,Marcks,Dst,Hcls1,Tpm4,Micall2,Whamm,Src,Myo1b,Ltbp2,Casp4,Carmil1,Fignl2,Triobp,Dync1h1,Rhoq,Rac3,Rnd1,Rhoc,Ccdc88b,Plod2,Pdgfrb,P4ha1,Fscn1,Plod3,Rhou,Plk3,Cenpj,Col11a2,Katna1,Zyx,Ezr,Nck1,Evl,Pstpip2 |
| 7.232e-04 | -7.23 | regulation of collagen biosynthetic process | biological process | GO:0032965 | 45 | 10 | 20694 | 1406 |
Rgcc,Serpine1,Adora2b,Ccl2,Il18,Errfi1,Pdgfrb,Prdx5,Pdgfb,Il6 |
| 7.232e-04 | -7.23 | spleen development | biological process | GO:0048536 | 45 | 10 | 20694 | 1406 |
Samd9l,Bcl2l11,Nfkb2,Cited2,Ahr,Pbx1,Ripk3,Fas,Jarid2,Tet2 |
| 7.258e-04 | -7.23 | cell projection organization | biological process | GO:0030030 | 1110 | 103 | 20694 | 1406 |
Flrt3,Jak2,Crkl,Abcc4,Notch1,Scarf1,Rilpl1,Pdgfb,Dst,Scn1b,Lpar1,Lrp4,Map4k4,Sema3c,Dock10,Map2k1,Snx10,Lst1,Hap1,Micall2,Rhoq,Triobp,Ntng2,Tsku,S1pr2,Fas,Lrp8,Flrt2,Carmil1,Igsf9,Itga4,Nectin2,Rac3,Clic5,Ptk2,Rab3ip,Tnc,Cenpj,Kif5c,Mecp2,Adora2a,Rhou,Pdpn,Ehd1,Evl,Intu,Sdc2,Ezr,Cnp,D1Ertd622e,Casp3,Gja1,Ptch1,Dnaaf3,Dbnl,Cdk5r1,Spire1,Nr4a3,Lyn,Klf7,Palld,Arf4,Btg2,Nes,Cyfip1,Il6,Phgdh,Ttc39c,Vasp,Plek,Prnp,Whamm,Lhx2,Rapgef2,Nrp2,Sema4a,Tmem67,Ext1,Psd,Igf1r,Rab10,Ccl5,Uchl1,Actb,Ift22,Fscn1,Sec24b,Rpgrip1l,Agrn,Mark2,Kdr,Egr2,Stxbp1,Snx2,Atp6v1d,Jun,P2ry12,Ift57,Fnbp1l,Nck1,Fcgr2b,Sdc4,Spata13 |
| 7.307e-04 | -7.22 | GAVIN_FOXP3_TARGETS_CLUSTER_P3 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P3 | 149 | 24 | 15632 | 1249 |
Samsn1,Ccrl2,Pou2f2,Ptprj,Sema4a,Gpd2,Il18,Ralgds,Pkp4,Rapgef5,Acpp,Tspan3,Casp3,Itgb8,Phlpp1,Rin2,Fgl2,Prdm1,Usp18,Cd74,Ppm1l,Sdc4,Pde3b,Cd80 |
| 7.349e-04 | -7.22 | RIP-mediated NFkB activation via ZBP1 | REACTOME pathways | R-MMU-1810476 | 14 | 6 | 8608 | 757 |
Nfkbia,Ikbkg,Nfkb1,Nfkb2,Nfkbib,Myd88 |
| 7.369e-04 | -7.21 | positive regulation of ATPase activity | biological process | GO:0032781 | 53 | 11 | 20694 | 1406 |
Dnaja1,Adrb2,Hspa2,Tor1aip1,Plscr1,Tor1aip2,Dnajb4,Dnajb2,Zc3hav1,Dnaja2,Ahsa1 |
| 7.482e-04 | -7.20 | GSE40666_UNTREATED_VS_IFNA_STIM_CD8_TCELL_90MIN_UP | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_CD8_TCELL_90MIN_UP | 132 | 22 | 15632 | 1249 |
Rtp4,Marcksl1,Ube2e1,Pim3,Lipg,Parp9,Tmem171,Ifi44,Gpd2,Serpinb9,Ifit3b,Ldha,Dusp5,Epsti1,Kitl,Plat,Ust,Cd274,Ifit3,Slc39a14,Slc7a5,Ppp4r2 |
| 7.490e-04 | -7.20 | ubiquitin-protein transferase activity | molecular function | GO:0004842 | 374 | 43 | 20217 | 1400 |
Dtx3l,Mdm2,Rnf145,Trim36,Malt1,Trim21,Rnf24,Ankib1,Trim12c,Fbxo4,Rnf135,Trim13,Cop1,Uba7,Birc2,Znrf1,Peli1,Ubr4,Rnf34,Herc6,Traf2,Rnf19a,Tnfaip3,Ube2e1,Trim56,Bfar,Trim12a,Mul1,Ube2l6,Rnf31,Birc3,Rffl,Rnf139,Rnf19b,Med21,Rnf14,Arel1,Trim30a,Rabgef1,Cnot4,Bcor,Ube2e2,Znrf3 |
| 7.491e-04 | -7.20 | GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_UP | MSigDB lists | GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_UP | 158 | 25 | 15632 | 1249 |
Snn,Gcnt2,Ralgds,Fam102b,Lyn,Itga5,Sema4c,Pde7b,Zc3h12c,Ahrr,Brwd3,Hvcn1,Gnb4,Fbrsl1,Slco3a1,Col18a1,Ube2e1,Ccng2,Kdm5b,Cish,Tcf4,Ets2,Arhgef3,Swap70,Gadd45b |
| 7.518e-04 | -7.19 | GO_TRANSCRIPTION_FACTOR_BINDING | MSigDB lists | GO_TRANSCRIPTION_FACTOR_BINDING | 495 | 60 | 15632 | 1249 |
Taf4b,Myc,Irf4,Jun,Hmga1,Psmd10,Fos,Psip1,Nfkbia,Rbl1,Ahr,Ifi207,Cd34,Ciita,Nlrp3,Ifi214,Kat2b,Bcor,Ifi203,Rnf19a,Sirt1,Med13,Ifi211,Zeb1,Spen,Lmo4,Mndal,Cav1,Nfkb1,Hcls1,Actb,Dr1,Trib1,Ifi204,Oasl1,Mtdh,Psma6,Mecp2,Mafk,Ccnd1,Hdac1,Egr2,Stat3,Ifi205,Rbbp8,Tcf4,Ifi209,Ifi213,Mdfic,Daxx,Pbx1,Hif1a,Hhex,Nfkbid,Ifi208,Fosb,Junb,Keap1,Nr4a3,Pim1 |
| 7.520e-04 | -7.19 | establishment or maintenance of cell polarity | biological process | GO:0007163 | 195 | 26 | 20694 | 1406 |
Gpsm2,Mark2,Rnd1,Rhoc,Rhoh,Arf4,Rpgrip1l,Fscn1,Rictor,Spry2,Frmd4a,Rnd3,Rab10,Igf1r,Crkl,Rhoq,Rhof,Spint2,Gja1,Pdzd11,Ezr,Ust,Lhx2,Cyth3,Syne2,Rhou |
| 7.565e-04 | -7.19 | GEORGANTAS_HSC_MARKERS | MSigDB lists | GEORGANTAS_HSC_MARKERS | 60 | 13 | 15632 | 1249 |
Tiparp,Fosb,Hopx,Klf2,Birc3,Rbpms,Rapgef2,H2-Aa,Arg2,H2-Ab1,Gbp2,Tnfsf10,Idi1 |
| 7.565e-04 | -7.19 | GO_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE | 60 | 13 | 15632 | 1249 |
Tnfaip3,Sphk1,Hif1a,Kdm6b,Fas,Il18rap,Sirt1,Il18bp,Mdm2,Il6,Bnip3,Klf2,Klf6 |
| 7.565e-04 | -7.19 | VANASSE_BCL2_TARGETS_DN | MSigDB lists | VANASSE_BCL2_TARGETS_DN | 60 | 13 | 15632 | 1249 |
Pla2g7,Nfkbid,Myc,Cyfip1,Map4k4,Ccr1,Samhd1,Abcc1,Dnase1l3,1600014C10Rik,Traf1,Ccnd2,Herc6 |
| 7.565e-04 | -7.19 | GO_VIRUS_RECEPTOR_ACTIVITY | MSigDB lists | GO_VIRUS_RECEPTOR_ACTIVITY | 60 | 13 | 15632 | 1249 |
Axl,Itgav,Cd86,Hspa1a,Htr2a,Ldlr,Cd80,Tnfrsf14,Cd55,Itga5,Icam1,Clec5a,F11r |
| 7.588e-04 | -7.18 | Il6st (interleukin 6 signal transducer) | protein interactions | 16195 | 9 | 5 | 7778 | 753 |
Lmo4,Stat1,Stat3,Socs3,Jak2 |
| 7.601e-04 | -7.18 | GO_REGULATION_OF_PHOSPHOLIPASE_C_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PHOSPHOLIPASE_C_ACTIVITY | 39 | 10 | 15632 | 1249 |
Prkce,Htr2a,Rasgrp1,Htr2b,Sele,Flt1,Ptafr,Pdgfrb,Gna15,Lpar1 |
| 7.601e-04 | -7.18 | regulation of dendritic cell cytokine production | biological process | GO:0002730 | 12 | 5 | 20694 | 1406 |
Tlr3,Nod2,Tlr9,Ddx58,Tlr2 |
| 7.601e-04 | -7.18 | histone mRNA catabolic process | biological process | GO:0071044 | 12 | 5 | 20694 | 1406 |
Dcp2,Atm,Tent2,Tent4a,Xrn1 |
| 7.601e-04 | -7.18 | G protein-coupled purinergic nucleotide receptor signaling pathway | biological process | GO:0035589 | 12 | 5 | 20694 | 1406 |
P2ry12,P2ry13,Ptafr,P2ry2,P2ry14 |
| 7.601e-04 | -7.18 | positive regulation of phospholipid biosynthetic process | biological process | GO:0071073 | 12 | 5 | 20694 | 1406 |
Htr2a,Pcx,Fabp3,Fpr2,Htr2b |
| 7.601e-04 | -7.18 | T-helper cell lineage commitment | biological process | GO:0002295 | 12 | 5 | 20694 | 1406 |
Il6,Spn,Irf4,Batf,Stat3 |
| 7.601e-04 | -7.18 | establishment of endothelial intestinal barrier | biological process | GO:0090557 | 12 | 5 | 20694 | 1406 |
F11r,Rap2c,Myd88,Icam1,Rapgef2 |
| 7.614e-04 | -7.18 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | MSigDB lists | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | 167 | 26 | 15632 | 1249 |
Prnp,Slc30a1,St3gal6,Cx3cl1,Plau,Tspo,Gng11,Crim1,Angpt1,Ifit1bl1,Axl,Agrn,Ets2,Tpst1,Nr3c1,Ppp2r5a,Rbpms,Cebpd,Acsl1,Lyn,Kdr,Gng12,Ifit1bl2,Rgl1,Sema3c,Kctd12 |
| 7.614e-04 | -7.18 | GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_UP | MSigDB lists | GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_UP | 167 | 26 | 15632 | 1249 |
Swap70,Klf6,Cxcl14,Ctsc,Dennd1b,Fchsd2,Fas,Mcoln2,Lrp8,Mdfic,Samhd1,Ahr,Gclc,Samsn1,Cd86,Snx10,Map4k4,Csrp1,Ccne1,G3bp2,Rab10,St3gal5,Tifa,Glrx,Cd82,Idi1 |
| 7.614e-04 | -7.18 | GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN | MSigDB lists | GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN | 167 | 26 | 15632 | 1249 |
Cpd,Ccng2,Pde1b,Setdb2,Pnp2,Itgav,Ccl12,Ripk3,Mapkbp1,Ubash3b,Fam133b,Tmtc2,Arrdc4,Atf3,Sh3bp4,Cd69,Srxn1,Phlda1,Zfp36,Psat1,Agpat4,Hsd17b7,Irak2,Nr4a3,Hmgcs1,Mtdh |
| 7.666e-04 | -7.17 | HSR_dom | interpro domains | IPR004865 | 7 | 4 | 19984 | 1430 |
Sp140,Sp110,A530032D15Rik,Sp100 |
| 7.666e-04 | -7.17 | Pept_T1A_subB | interpro domains | IPR000243 | 7 | 4 | 19984 | 1430 |
Psmb6,Psmb8,Psmb9,Psmb10 |
| 7.682e-04 | -7.17 | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_DN | MSigDB lists | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_DN | 176 | 27 | 15632 | 1249 |
Snx2,Slamf9,Cnn3,Tlr1,Ampd3,Ifit1bl2,Rnf31,Card6,Snn,Frmd6,Inpp1,Aida,Fam111a,Prdx5,Irgm2,Il4i1,Stard5,Zyx,Ifit1bl1,Ctu1,Daxx,Slc28a2,Sdc4,Zbtb5,Pnpt1,Sell,Rnf139 |
| 7.682e-04 | -7.17 | GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_UP | MSigDB lists | GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_UP | 176 | 27 | 15632 | 1249 |
Traf1,Irs2,Rars,Prpf38a,Ahr,Gclc,Ptpn2,Ets2,Ankrd17,Sbds,Ythdf1,Ifrd1,Tor1aip2,Gpd2,Ppa1,Slc31a1,Snn,Gfi1,Ccl4,Fubp1,Casp4,Rrs1,Irf8,Nampt,Stat4,Zfp36,Slc7a5 |
| 7.682e-04 | -7.17 | GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_UP | MSigDB lists | GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_UP | 176 | 27 | 15632 | 1249 |
Notch2,Sema4a,Ms4a6d,Mppe1,Il18rap,Sirt1,Med13,Gpr132,Pde4b,Mark2,Gpc1,Crlf3,Itga4,H2-Q7,Pgs1,Taf4b,Arhgap26,Errfi1,Ppp2r5a,Setdb2,D1Ertd622e,Mgat1,H2-Q6,Swap70,H2-Q4,Dync1h1,Klf3 |
| 7.682e-04 | -7.17 | GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN | MSigDB lists | GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN | 176 | 27 | 15632 | 1249 |
Rasgrp1,Trim56,Usp12,Tlr1,Atxn7l1,Btg2,Card6,Snn,Ikbke,Slfn9,Cflar,Frmd4a,Spata5l1,Filip1l,Egr3,St3gal1,Tlk2,Nr3c1,Slfn8,Slfn5,Hvcn1,Bfar,Sell,Ppm1l,Calcrl,Bcor,Evl |
| 7.682e-04 | -7.17 | GSE3982_EOSINOPHIL_VS_MAC_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAC_UP | 176 | 27 | 15632 | 1249 |
Syne2,Isg20,Itgal,Tnfrsf1b,Jarid2,Tax1bp1,Actb,Fpr1,Mmp25,Pim2,Mtmr14,Treml2,Gpr35,Slc44a1,Pla2g4a,Ptpn2,Acpp,Fos,Parp8,Klf3,Notch1,Cutc,Sla,Cdk5r1,Isg15,Prrg4,Hhex |
| 7.682e-04 | -7.17 | GSE3982_EOSINOPHIL_VS_DC_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_DC_UP | 176 | 27 | 15632 | 1249 |
Rhoh,Zfp281,Cutc,Cd34,Myd88,Hck,Notch1,Flrt3,Klf3,Ankrd17,D16Ertd472e,Rgs14,Stap1,Ccr3,Kdm6b,Fpr1,Irf1,Acvr1b,H3f3b,Jarid2,Rabgef1,Ppp1r15a,Ampd3,Isg20,Inpp5b,Xaf1,Syne2 |
| 7.700e-04 | -7.17 | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_DN | 185 | 28 | 15632 | 1249 |
Fndc3a,Smox,Ptprj,Ier3,Acvr1b,Sec24a,Snapc1,Gem,Serpine1,Ppp1r15a,Zeb1,Etv6,Stoml1,Csrnp1,Cdkn2d,Slc30a4,Upp1,Prnp,Tulp3,Ube2f,Rbms2,Myo10,Gramd1a,Rbbp8,Gpr18,Timp1,Carhsp1,Treml2 |
| 7.700e-04 | -7.17 | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN | 185 | 28 | 15632 | 1249 |
Irf8,Plod2,Lap3,Psat1,Mmd,Hat1,Ddit4,Flnb,Trip13,Rcsd1,Frmd4a,Cxcl10,Mthfd2,Sema4c,Pcgf5,Gca,Phlpp1,Optn,Rsad2,Dusp4,Casp3,Myc,Egr2,Ubash3b,Rtp4,Aim2,Etv5,Cd83 |
| 7.700e-04 | -7.17 | GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_DN | MSigDB lists | GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_DN | 185 | 28 | 15632 | 1249 |
1110038F14Rik,Rffl,Ubtd2,Rgs14,Rhbdf2,Cd40,Ifit1bl1,Morc3,Casp1,Ifnar1,Hvcn1,Tle3,Ciita,Crlf3,Etv3,Kmo,Ppm1l,Dtx3l,Snx2,Ampd3,Casp8,Ifit1bl2,Tuba4a,Adam19,Aida,Map3k8,Azi2,Filip1l |
| 7.700e-04 | -7.17 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN | 185 | 28 | 15632 | 1249 |
Tnc,Stk40,Cers6,Rsad2,Nfkbie,Abcc5,Tnf,Rnf139,Traf1,Cdk5r1,Hif1a,Trim21,Rasgrp1,Rnf19a,Oas1a,Arid4a,Jarid2,Dmwd,Mov10,Cnp,Abcc4,Acp2,Rcl1,Kif5c,Oas1g,Egr3,St3gal1,Cxcl10 |
| 7.700e-04 | -7.17 | GSE2826_WT_VS_BTK_KO_BCELL_DN | MSigDB lists | GSE2826_WT_VS_BTK_KO_BCELL_DN | 185 | 28 | 15632 | 1249 |
Prdx1,Cd14,Chmp4b,Il1a,Traf1,Casp3,Cpd,P4ha2,Axl,Ccl12,Znfx1,Traf2,Spic,Vcam1,Thbs1,Gng12,Glrx,Hp,Hmox1,Tgfbi,Acsl1,Il18,S100a8,Rgl1,P4ha1,Ahrr,Gbp7,Lap3 |
| 7.700e-04 | -7.17 | GSE27859_CD11C_INT_F480_HI_MACROPHAGE_VS_CD11C_ING_F480_INT_DC_DN | MSigDB lists | GSE27859_CD11C_INT_F480_HI_MACROPHAGE_VS_CD11C_ING_F480_INT_DC_DN | 185 | 28 | 15632 | 1249 |
Ccng2,Dusp2,Sat1,Gramd1a,Apaf1,Tspo,Il4ra,Gbp3,Col18a1,Prdm1,Pgs1,Kctd12,Egln3,Zc3h7a,Btg2,Wdfy1,Ednrb,Pde4b,Ankib1,Ap3m2,Snn,Slc37a3,Tmem123,Znrf1,Chic2,Tmem229b,4930453N24Rik,Rnf19b |
| 7.700e-04 | -7.17 | GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_UP | MSigDB lists | GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_UP | 185 | 28 | 15632 | 1249 |
Cst7,Agrn,Nr4a1,Atp13a1,Acvrl1,Cish,Traf1,Ifih1,Isg15,Slco3a1,Atp11a,Psme1,Fas,Klf7,Notch1,Ifit1,Batf,Irf7,Pdgfrb,Hopx,Ccl5,Tnfrsf1b,Dgka,Sema4a,Ms4a6d,Socs3,Tnip1,Znrf1 |
| 7.700e-04 | -7.17 | GSE34515_CD16_POS_MONOCYTE_VS_DC_DN | MSigDB lists | GSE34515_CD16_POS_MONOCYTE_VS_DC_DN | 185 | 28 | 15632 | 1249 |
Pigv,Dtx3l,Ddx60,Notch1,Ifit1,Plagl2,Slc28a2,Bmp2,Fcgr1,Cd302,Ifit2,Nlrc5,Klf6,Parp14,Ms4a6d,Fcho2,Tlr2,Cxcl10,Map3k8,Epsti1,Gtpbp2,Irf8,Itgal,Gdf15,Ccrl2,Pstpip2,Ampd3,Tifa |
| 7.707e-04 | -7.17 | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | MSigDB lists | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | 297 | 40 | 15632 | 1249 |
Zyx,Phldb1,Tagln,Rin2,Sat1,Tnc,Stat2,Papss2,Sphk1,Isg15,Mxd1,Nfkbiz,Csrnp1,Rgs3,Klf7,Aff1,Angpt1,Slfn5,Mvp,Plau,Pid1,Klf2,Gem,Card6,Tshz1,Lnpep,Phlda1,Flnb,4930453N24Rik,Ier3,Cdc42ep4,Arid5b,Lox,Frmd4a,Smox,Il13ra1,Igf2bp2,Fmnl2,Frmd6,Orai2 |
| 7.726e-04 | -7.17 | stress-activated protein kinase signaling cascade | biological process | GO:0031098 | 125 | 19 | 20694 | 1406 |
Zfp36,Myd88,Mlkl,Map4k4,Map2k4,Map2k1,Mapkapk2,Ptk2,Errfi1,Ptger4,Nek6,Syk,Tnf,Mapkbp1,Mdfic,Mul1,Trib1,Ripk2,Map3k8 |
| 7.728e-04 | -7.17 | regulation of carbohydrate metabolic process | biological process | GO:0006109 | 185 | 25 | 20694 | 1406 |
Pdk3,Ddit4,Dyrk2,Src,Plek,Stat3,Nr3c1,Gfpt1,Ptafr,Hif1a,Il6,Ptger4,Pdgfb,Ranbp2,Ptpn2,Ier3,Sirt1,Myc,Htr2a,Nupr1,Prkce,Rubcnl,Nfkb1,Kat2b,Irs2 |
| 7.738e-04 | -7.16 | positive regulation of proteasomal protein catabolic process | biological process | GO:1901800 | 106 | 17 | 20694 | 1406 |
Tmem67,Hspa1a,Dnajb2,Trib1,Psmd10,Ankib1,Plk3,Nupr1,Rnf14,Rnf19a,Mdm2,Plk2,Hspa1b,Rnf19b,Cop1,Trib3,Gclc |
| 7.749e-04 | -7.16 | positive regulation of small GTPase mediated signal transduction | biological process | GO:0051057 | 70 | 13 | 20694 | 1406 |
Notch2,Lpar1,Kitl,Gpr18,Csf1,Map4k4,Gpr35,Pdgfrb,Src,Rasgrp1,Prag1,Notch1,Map2k1 |
| 7.749e-04 | -7.16 | regulation of signal transduction by p53 class mediator | biological process | GO:1901796 | 70 | 13 | 20694 | 1406 |
Psmd10,Rffl,Rnf34,Eef1e1,Spred1,Kmt5a,Atm,Rrs1,Spred3,Cd74,Pmaip1,Sirt1,Mdm2 |
| 7.751e-04 | -7.16 | cysteine-type endopeptidase activity | molecular function | GO:0004197 | 95 | 16 | 20217 | 1400 |
Adgb,Usp35,Cflar,Usp12,Usp42,Casp4,Casp2,Casp7,Uchl1,Casp1,Ctsc,Malt1,Casp8,Casp3,Usp18,Usp25 |
| 7.751e-04 | -7.16 | ubiquitin-like protein binding | molecular function | GO:0032182 | 95 | 16 | 20217 | 1400 |
Tnfaip3,Daxx,Dnajb2,Birc2,Mdm2,Dcun1d3,Sqstm1,Rnf19b,Optn,Ikbkg,Ube2l6,Pml,Rnf31,Nr3c1,Tax1bp1,Uchl1 |
| 7.763e-04 | -7.16 | activated TAK1 mediates p38 MAPK activation | REACTOME pathways | R-MMU-450302 | 19 | 7 | 8608 | 757 |
Nod1,Irak2,Tab2,Ripk2,Mapkapk2,Nod2,Ikbkg |
| 7.772e-04 | -7.16 | neuron projection development | biological process | GO:0031175 | 689 | 69 | 20694 | 1406 |
Sdc4,Fcgr2b,Sdc2,Cnp,Evl,Adora2a,Ehd1,Jun,Tnc,Stxbp1,Kif5c,Egr2,Kdr,Mecp2,Agrn,Clic5,Rac3,Ptk2,Mark2,Actb,Sec24b,Itga4,Fas,Rab10,Lrp8,Flrt2,Igsf9,Uchl1,Ntng2,Tsku,Ext1,Triobp,Igf1r,Psd,Map2k1,Dock10,Lst1,Sema4a,Micall2,Hap1,Sema3c,Nrp2,Rapgef2,Map4k4,Lhx2,Phgdh,Vasp,Lrp4,Scn1b,Dst,Il6,Cyfip1,Notch1,Scarf1,Palld,Arf4,Btg2,Nr4a3,Spire1,Cdk5r1,Klf7,Lyn,Gja1,Ptch1,Casp3,Jak2,Flrt3,Crkl,Dbnl |
| 7.774e-04 | -7.16 | negative regulation of nervous system development | biological process | GO:0051961 | 359 | 41 | 20694 | 1406 |
Zhx2,Cav1,Kremen1,Pbx1,Fas,Cdk5r1,Tlr2,Rap1gap2,Ifrd1,Stap1,Sema4c,Il15ra,Dync1i2,Ptk2,Gfi1,Prag1,Il1b,Hmga2,Notch1,Mdm2,Ednrb,Lrp4,Tspo,Lpar1,Tnf,Jag1,Mecp2,Kdm4a,Tulp3,Casz1,Sema4a,Katna1,Ctsc,Ldlr,Cd38,Sema3c,Rapgef2,Plk2,Map4k4,Lhx2,Stat3 |
| 7.782e-04 | -7.16 | epithelial cell development | biological process | GO:0002064 | 227 | 29 | 20694 | 1406 |
Clic4,Flnb,Fndc3a,Triobp,F11r,Gja1,Spint2,Col18a1,Notch2,Frmd6,Myadm,Icam1,Sec24b,Plod3,Slc4a7,Palld,Clic5,Notch1,Pdgfb,Rilpl1,Arid4a,Hif1a,Jag1,Rapgef2,Prdm1,Met,Myd88,Ezr,Rap2c |
| 7.784e-04 | -7.16 | GO_RESPONSE_TO_VITAMIN | MSigDB lists | GO_RESPONSE_TO_VITAMIN | 99 | 18 | 15632 | 1249 |
Pla2g4a,Tnc,Fzd1,Ccnd1,Mdm2,Ccl12,Ccne1,Ccl5,Eif2ak2,Tspo,Il15,Il1b,Mthfr,Cdkn2d,Hmgcs1,Cxcl10,Pim1,Ptgs2 |
| 7.808e-04 | -7.16 | GSE11386_NAIVE_VS_MEMORY_BCELL_DN | MSigDB lists | GSE11386_NAIVE_VS_MEMORY_BCELL_DN | 141 | 23 | 15632 | 1249 |
Filip1l,Etnk1,St7,Il12b,Phyh,Ikbke,Chd9,Plod2,Rel,Trim14,Ddit4,Xaf1,Rictor,Evl,Ifih1,Traf1,Gbe1,Traf5,Slc28a2,Nlrc5,Peli1,Mdn1,Kdm5b |
| 7.850e-04 | -7.15 | GO_REGULATORY_REGION_NUCLEIC_ACID_BINDING | MSigDB lists | GO_REGULATORY_REGION_NUCLEIC_ACID_BINDING | 714 | 81 | 15632 | 1249 |
Junb,Arid4a,Jarid2,Fosb,Irf7,Ifi208,Arid5b,Nr4a3,Nfxl1,Nfkb2,Tnf,Ifi213,Arid5a,Tcf4,Bcl6,Ifi209,Ifi205,Stat3,Nr3c1,Egr2,Batf2,Aebp2,Hdac1,Mafk,Cebpd,Prdx5,Hhex,Prdm1,Irf2,Mxd1,Zfp513,Zfp281,Batf,Pbx1,Tal2,Etv5,Notch1,Relb,Nfkb1,Jdp2,Irf8,Rel,Mndal,Lmo4,Zeb1,Ifi211,Sirt1,Hivep3,Stat4,Pou2f2,Etv6,Ifi203,Max,Stat1,Irf1,Ifi204,Actb,H3f3b,Nfil3,Gfi1,Nlrc5,Hivep2,Fos,Ets2,Jun,Tiparp,Ikzf1,Irf4,Myc,Atf3,Egr1,Bcor,Kat2b,Plagl1,Etv3,Ifi214,Nr1h3,Ciita,Hinfp,Ifi207,Ahr |
| 7.865e-04 | -7.15 | p53-Dependent G1 DNA Damage Response | REACTOME pathways | R-MMU-69563 | 62 | 14 | 8608 | 757 |
Psmb6,Psme1,Atm,Psmb9,Cop1,Psma6,Psme2,Psme2b,Psmd10,Ccne1,Psmb8,Mdm2,Cdkn1a,Psmb10 |
| 7.865e-04 | -7.15 | p53-Dependent G1/S DNA damage checkpoint | REACTOME pathways | R-MMU-69580 | 62 | 14 | 8608 | 757 |
Psmb6,Psme1,Psmb9,Atm,Cop1,Psma6,Psme2,Psme2b,Ccne1,Psmd10,Psmb8,Mdm2,Cdkn1a,Psmb10 |
| 7.865e-04 | -7.15 | HSR | pfam domains | PF03172 | 7 | 4 | 18711 | 1348 |
Sp110,A530032D15Rik,Sp140,Sp100 |
| 7.894e-04 | -7.14 | GO_APOPTOTIC_MITOCHONDRIAL_CHANGES | MSigDB lists | GO_APOPTOTIC_MITOCHONDRIAL_CHANGES | 53 | 12 | 15632 | 1249 |
Gclc,Bcl2a1a,Bcl2a1d,Hk2,Bnip3,Gclm,Ggct,Jun,Sod2,Bcl2l11,Bcl2a1b,Ifit2 |
| 7.894e-04 | -7.14 | cell-cell adhesion | biological process | GO:0098609 | 382 | 43 | 20694 | 1406 |
Cx3cl1,Pdpn,Tnf,P2ry12,Olr1,Stxbp1,Itga5,Plpp3,Syk,Ubash3b,Acvr1,Vezt,S100a8,Cx3cr1,Pvr,Plek,Cd34,Spn,Ccl5,Pkp4,Cd200,Icam1,Cdk5r1,Igsf9,Sell,Tnip1,Slc7a11,Ntng2,Itgav,Stxbp3,Flrt3,Vcam1,Nlgn2,Fndc3a,Il1b,Nectin2,Lgals9,Cd164,Sele,Itgal,Nectin4,Palld,Itga4 |
| 7.916e-04 | -7.14 | membrane organization | biological process | GO:0061024 | 569 | 59 | 20694 | 1406 |
Rubcnl,Msr1,Stx6,Nlgn2,Tor1aip1,Nectin2,Rac3,Agrn,Lpcat2,Sec24b,Myc,Bnip3,Ap3b1,Spaca6,Fchsd2,Fcho2,Stxbp1,Abcb1a,Fcgr2b,Xkr8,Abcc1,Etv5,Cnp,Rab20,Stard5,Fcgr1,Slc9a1,Spire1,Myadm,Parp11,Mx2,Cav1,Atp11a,Marco,Mx1,Rtp4,Samd9l,Vcpip1,Hk2,Chmp4b,Pmaip1,Ier3,Sgcb,Cox18,Atp11b,Mul1,Lrp4,Syne2,Rilpl1,Atp10a,Stx11,Sec24a,Mitd1,Plscr1,Stat3,Bcl2l11,Whamm,Treml4,Thbs1 |
| 7.939e-04 | -7.14 | - | gene3d domains | 3.30.720.50 | 10 | 5 | 8819 | 755 |
Parp11,Dtx2,Parp12,Zc3hav1,Parp14 |
| 7.951e-04 | -7.14 | GNF2_S100A4 | MSigDB lists | GNF2_S100A4 | 46 | 11 | 15632 | 1249 |
Fgr,Hck,Glrx,Tnfsf10,Pilra,Casp1,Tnfrsf1b,Ccr1,Fgl2,Nod2,Igsf6 |
| 7.951e-04 | -7.14 | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_UP | MSigDB lists | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_UP | 46 | 11 | 15632 | 1249 |
Plagl1,Bcl6,Egr3,Cdkn2d,Fgl2,Rhoc,Adora2a,Spen,Jak2,Tlr1,Clic4 |
| 7.951e-04 | -7.14 | GO_HEXOSE_CATABOLIC_PROCESS | MSigDB lists | GO_HEXOSE_CATABOLIC_PROCESS | 46 | 11 | 15632 | 1249 |
Pfkfb3,Fut8,Pgk1,Hk2,Pfkl,Hk3,Tpi1,Hk1,Eno2,Eno1,Pgm1 |
| 7.951e-04 | -7.14 | GO_POSITIVE_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS | 46 | 11 | 15632 | 1249 |
Src,Flt1,Pdgfrb,Pdgfb,Nod2,Ptk2,Lyn,Fabp3,Fgr,Htr2a,Htr2b |
| 8.048e-04 | -7.12 | regulation of mitochondrial membrane potential | biological process | GO:0051881 | 79 | 14 | 20694 | 1406 |
Tspo,Sod2,Mul1,Adora2a,Prkce,Kdr,Pmaip1,Casp1,Pid1,Gclc,Bnip3,Gclm,Myc,Src |
| 8.055e-04 | -7.12 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | 150 | 24 | 15632 | 1249 |
Ikzf1,Myc,Ccnd1,Taf4b,Mid1,Ppp6r1,Agrn,Itgav,Tmem184b,Gng11,Gpc1,Sla,Mxd1,Rhoh,Pml,Cnn3,Trim14,Noc4l,Pdss1,Slc25a12,Sh3bp4,Samsn1,Plk2,Hcls1 |
| 8.055e-04 | -7.12 | GTCTTCC_MIR7 | MSigDB lists | GTCTTCC_MIR7 | 150 | 24 | 15632 | 1249 |
Irs2,Cyth3,Ppfia3,Kcnj2,Serp1,Rnf114,Nlgn2,Igf2bp2,Arf4,Rsbn1,Nr4a3,Pik3cd,Mafg,Pim1,Ptk2,Egr3,Fam53c,Sema4c,G3bp2,Ddit4,Cnn3,Flrt2,Arid4a,Dach1 |
| 8.109e-04 | -7.12 | antigen processing and presentation via MHC class Ib | biological process | GO:0002475 | 38 | 9 | 20694 | 1406 |
H2-M2,H2-T10,H2-T24,Ap3b1,H2-Q4,H2-Q7,Tap2,H2-T22,H2-Q6 |
| 8.110e-04 | -7.12 | positive regulation of reproductive process | biological process | GO:2000243 | 88 | 15 | 20694 | 1406 |
Prdm9,Pde5a,Plau,Il18,Src,Ednrb,Igf1r,Cited2,Ptger4,Abcb1a,Plat,Acvr1b,Ptafr,Inhba,P2ry2 |
| 8.158e-04 | -7.11 | adrenal gland development | biological process | GO:0030325 | 24 | 7 | 20694 | 1406 |
Nr3c1,Cited2,Igf1r,Arid5b,Pdgfrb,Hmga2,Pbx1 |
| 8.206e-04 | -7.11 | primary neural tube formation | biological process | GO:0014020 | 116 | 18 | 20694 | 1406 |
Vasp,Fzd1,Phactr4,Tulp3,Cited2,Casp3,Ptch1,Mthfr,Lmo4,Spint2,Sema4c,Hif1a,Sdc4,Lhx2,Sec24b,Ift57,Apaf1,Mthfd1l |
| 8.233e-04 | -7.10 | TCF1P_Q6 | MSigDB lists | TCF1P_Q6 | 241 | 34 | 15632 | 1249 |
Tle3,Mark2,Rbms2,Gmppb,Hif1a,Col18a1,Arhgap26,Ncoa5,Dusp8,Edn1,Sat1,Tet2,Fos,Klf3,Cdkn1a,Nlgn2,Stard7,Kitl,Kif3c,Il12b,Pik3cd,Trib1,Itpkc,Hmgcs1,Cpeb4,Etv6,Fzd1,Med13,Sik3,Lmo4,Jarid2,Atm,Ttc9c,Cdyl |
| 8.260e-04 | -7.10 | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_DN | MSigDB lists | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_DN | 68 | 14 | 15632 | 1249 |
Pim2,Cd55,Evl,Nfkbiz,Il4ra,Ier3,Samhd1,Hck,Psat1,Birc3,Jun,Scn1b,Mdn1,Uba7 |
| 8.260e-04 | -7.10 | GNF2_PTPRC | MSigDB lists | GNF2_PTPRC | 68 | 14 | 15632 | 1249 |
Parp12,Klf2,H2-Q6,Lcp2,Itgal,Casp8,H2-Q4,Parp8,Phf11b,Phf11c,Hcls1,Phf11a,Phf11d,H2-Q7 |
| 8.260e-04 | -7.10 | HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | MSigDB lists | HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | 68 | 14 | 15632 | 1249 |
Tagln,Ass1,Vcan,Inhba,Il6,Mmp25,Ier3,Icam1,Cdkn1a,Olfml3,Tnfaip3,Relb,Sdc4,Col4a2 |
| 8.261e-04 | -7.10 | REACTOME_SIGNALLING_BY_NGF | MSigDB lists | REACTOME_SIGNALLING_BY_NGF | 204 | 30 | 15632 | 1249 |
Map2k1,Dusp6,Adora2a,Casp2,Rictor,Akt3,Trib3,Ripk2,Prkar2b,Cdkn1a,Ppp2r1b,Ralgds,Arhgef3,Bcl2l11,Sqstm1,Src,Nfkbia,Nr4a1,Dusp4,Mdm2,Hdac1,Phlpp1,Pde1b,Prkce,Casp3,Stat3,Irs2,Mapkapk2,Abr,Myd88 |
| 8.294e-04 | -7.09 | G protein-coupled purinergic nucleotide receptor activity | molecular function | GO:0045028 | 12 | 5 | 20217 | 1400 |
Ptafr,P2ry2,P2ry14,P2ry13,P2ry12 |
| 8.294e-04 | -7.09 | G protein-coupled nucleotide receptor activity | molecular function | GO:0001608 | 12 | 5 | 20217 | 1400 |
P2ry2,P2ry14,P2ry13,P2ry12,Ptafr |
| 8.304e-04 | -7.09 | REACTOME_APOPTOSIS | MSigDB lists | REACTOME_APOPTOSIS | 133 | 22 | 15632 | 1249 |
Psme1,Ptk2,Casp7,Fas,Psmb6,Psmb10,Cflar,Tnfsf10,Apaf1,Psmb8,Tnf,Bcl2l11,Psmd10,Psmb9,Traf2,Casp8,Birc2,Casp3,Cycs,Dbnl,Psme2,Psma6 |
| 8.304e-04 | -7.09 | MODULE_122 | MSigDB lists | MODULE_122 | 133 | 22 | 15632 | 1249 |
Ccl12,Itgav,Ccr1,Cx3cr1,Csf3r,Zyx,Itgal,Tnc,Apba1,Itga5,Col18a1,Sell,Rnd1,Il18,Cx3cl1,Fpr2,Icam1,Tgfbi,Ccl4,Rnd3,Vcam1,Ppfibp1 |
| 8.340e-04 | -7.09 | GSE12366_GC_VS_NAIVE_BCELL_UP | MSigDB lists | GSE12366_GC_VS_NAIVE_BCELL_UP | 168 | 26 | 15632 | 1249 |
Daam1,Vezt,Ccne1,Plek,Met,Syne2,Tifa,Asb13,Nr4a3,Sema4a,Chic2,Clic4,Gfpt1,Bcl6,Psmd10,Rapgef5,Psip1,Cenpe,Hspa2,Dennd1b,Tnfsf8,Casp3,Slco3a1,Samhd1,Prpf38a,Cd38 |
| 8.340e-04 | -7.09 | GSE3982_DC_VS_BCELL_DN | MSigDB lists | GSE3982_DC_VS_BCELL_DN | 168 | 26 | 15632 | 1249 |
Arid5b,Mefv,Zhx2,Thbs1,Sik3,Ptch1,Irf7,Irf8,Klf2,Itgal,Rabgef1,Oas2,Tpx2,Arl4a,Rhoh,H2-Q7,Plagl2,Crlf3,Ciita,Cd34,Ankrd17,D16Ertd472e,Rgs14,H2-Q6,H2-Q4,Dusp1 |
| 8.349e-04 | -7.09 | 4_helix_cytokine-like_core | interpro domains | IPR009079 | 84 | 15 | 19984 | 1430 |
Il10,Csf1,Il15,Ifna4,Csf3,Ifna5,Ifna2,Ifnb1,Kitl,Ifna6,Il6,Clcf1,Osm,Ifna1,Lif |
| 8.351e-04 | -7.09 | actin filament organization | biological process | GO:0007015 | 228 | 29 | 20694 | 1406 |
Marcks,Vasp,Rhou,Pstpip2,Evl,Nck1,Casp4,Myo1b,Src,Whamm,Ezr,Micall2,Zyx,Tpm4,Hcls1,Dbnl,Rhoq,Rhof,Triobp,Carmil1,Spire1,Rnd3,Fscn1,Swap70,Rnd1,Rhoc,Diaph2,Rhoh,Rac3 |
| 8.368e-04 | -7.09 | CD20-like | interpro domains | IPR007237 | 23 | 7 | 19984 | 1430 |
Ms4a6c,Ms4a6b,Ms4a6d,Ms4a4b,Tmem176a,Tmem176b,Ms4a4c |
| 8.391e-04 | -7.08 | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN | MSigDB lists | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN | 186 | 28 | 15632 | 1249 |
Acvrl1,Ifi44,Tor1aip2,Ikzf1,Itpr1,Acpp,Gypc,P4ha2,Dpy19l1,Rbl1,Myo10,Tnfrsf14,Ripk3,Hvcn1,Pde3b,Slco3a1,Ddx58,Syne2,Oas2,G3bp2,Tuba4a,Tshz1,Atm,Sema4a,Gpd2,Lyn,Mob3b,Tmem229b |
| 8.391e-04 | -7.08 | GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_DN | MSigDB lists | GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_DN | 186 | 28 | 15632 | 1249 |
Stk40,Ppfia3,Ccnd1,Phlpp1,Gpr84,H2-Q6,Swap70,Rapgef5,Plac8,H2-Q4,Cx3cr1,Zfp319,Arg2,Icam1,Nupr1,Nfkbiz,H2-Q7,Mcm10,Il12rb1,Inhba,Icosl,Klf2,Frmd6,Pfkl,Sema4a,Fpr1,Ier3,Uchl1 |
| 8.391e-04 | -7.08 | GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_DN | 186 | 28 | 15632 | 1249 |
Rasgrp1,Uba7,Tlr1,Nmi,Inpp5b,Sipa1l1,Ccl5,Sesn3,Pde4b,Ikbke,Irak2,Plcl2,Clcf1,Kcna3,Acvr1b,Kremen1,Peli1,Ikzf1,Dse,Ifnar1,Trim36,Cnn2,Daxx,Crim1,Sgk3,Cd74,Tlr6,Evl |
| 8.391e-04 | -7.08 | GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_DN | MSigDB lists | GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_DN | 186 | 28 | 15632 | 1249 |
Pdk3,Zc3h12c,Gbp7,Ddit4,Tmod3,Pim1,Phyh,Clcn7,Sh3bgrl2,Tmem123,Igf1r,Glrx,Plac8,Casp1,Ass1,Eno1,Fut8,Myc,Fgl2,Ube2e1,Tmem176b,Prdm1,Mcoln2,Atp11a,Gbp3,Il15,Cd80,Hck |
| 8.391e-04 | -7.08 | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN | 186 | 28 | 15632 | 1249 |
Pik3r6,Ccl5,Myadm,Tmem26,Kctd12,AA467197,Rasgrp1,Ociad1,Csf1,Rcn1,Ptger4,Vegfc,Agpat4,Ap3m2,Gfi1,Cdkn1a,Glrx,Tfec,Cflar,Msr1,Cyfip1,Acpp,Fgl2,Abcb1a,Rhoq,Ubash3b,Rgs3,1600014C10Rik |
| 8.391e-04 | -7.08 | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP | 177 | 27 | 15632 | 1249 |
Ppp1r15b,Cd274,Sik3,Phlda1,Pcgf5,Dusp5,Serpinb9,Zcchc2,Epsti1,Il15ra,Vrk2,Hsph1,Cenpe,Morc3,Ifit2,Psip1,Trmt1l,Itpr1,Arhgef3,Hspa1a,Dennd1b,Tnfsf8,Mid1,Aim2,Plagl1,Sell,Crim1 |
| 8.391e-04 | -7.08 | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | MSigDB lists | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | 177 | 27 | 15632 | 1249 |
Rnf135,Aim2,Stxbp1,Mcoln2,Ncoa7,Trip10,Plekha5,Txnrd1,Nqo1,Gpr68,Ctsc,Casp3,Pde1b,Ifi35,Ell2,Dusp16,Jak2,Inpp1,Ldlr,Adam19,Cd82,Lmo4,Plekha2,Ccne1,Rapgef2,Rnf19a,Tifa |
| 8.391e-04 | -7.08 | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_UP | MSigDB lists | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_UP | 177 | 27 | 15632 | 1249 |
Pml,Lif,Dtx3l,Arrdc4,Usp18,Tsku,Gbp2,Ifit1bl1,Jun,Fos,Lrch1,Oas1g,Socs3,Mtmr14,Slc25a22,Nfkb1,Ccl5,Ifit1bl2,Junb,Casp4,Gbp7,Cd274,Irf8,Ube2l6,Etv6,Spint2,Oas1a |
| 8.391e-04 | -7.08 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | 177 | 27 | 15632 | 1249 |
Gadd45b,Sqstm1,Rnf114,Bcl6,Tbc1d1,Slc15a3,4932438A13Rik,Nod2,Acvr1,Nfkbie,Egr1,Upp1,Atp11a,Hinfp,Myd88,Atp11b,Rhoc,Map4k4,Tnfrsf1b,Zc3h7a,H2-Aa,Tyk2,Egr3,Serpinb9,Polr2g,Nfkb2,Ralgds |
| 8.391e-04 | -7.08 | GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN | MSigDB lists | GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN | 177 | 27 | 15632 | 1249 |
Plk2,Daam1,Klf2,Rel,Irf8,Hopx,Slc31a2,Rap1gap2,Tgfbi,Arid5b,Azi2,Hmgcs1,Cd55,Gfpt1,Clic4,Slc25a37,Phlpp1,Vcan,Chst11,Stat3,Ppp2r5a,Plagl1,Ifih1,Itga4,Ahr,Vcpip1,Tnfaip3 |
| 8.391e-04 | -7.08 | GSE369_IFNG_KO_VS_WT_LIVER_UP | MSigDB lists | GSE369_IFNG_KO_VS_WT_LIVER_UP | 177 | 27 | 15632 | 1249 |
Zc3h7a,Rictor,Dusp6,Rnaset2a,Asah2,Cflar,Zcchc2,Elmod2,Cd82,Rnaset2b,Smc5,Itga9,Rnf145,Nr4a3,Irgq,Pde1b,Nfkbie,Ccng2,Phactr4,Cenpe,Slamf7,Pde3b,Tnfaip3,Prdm1,Cdk5r1,Arl4a,St3gal6 |
| 8.467e-04 | -7.07 | mouse chr12 B1|12 18.06 cM | chromosome location | mouse chr12 B1|12 18.06 cM | 4 | 3 | 24173 | 1464 |
Dock4,Arl4a,Ifrd1 |
| 8.559e-04 | -7.06 | SUBTIL_PROGESTIN_TARGETS | MSigDB lists | SUBTIL_PROGESTIN_TARGETS | 33 | 9 | 15632 | 1249 |
Sap30,Bnip3,Ccnd1,Cebpd,Dusp1,Atf3,Abcc5,Kat2b,Jun |
| 8.559e-04 | -7.06 | GO_CELLULAR_RESPONSE_TO_DSRNA | MSigDB lists | GO_CELLULAR_RESPONSE_TO_DSRNA | 33 | 9 | 15632 | 1249 |
Mul1,Cav1,Nfkb1,Tlr3,Ifit1bl2,Ifit1bl1,Ifnb1,Zc3hav1,Adar |
| 8.559e-04 | -7.06 | NAKAMURA_ADIPOGENESIS_EARLY_DN | MSigDB lists | NAKAMURA_ADIPOGENESIS_EARLY_DN | 33 | 9 | 15632 | 1249 |
Hck,Rai14,Il6,Vcam1,Lox,Serpine1,Gdf15,Itgav,Ier2 |
| 8.559e-04 | -7.06 | GO_RESPONSE_TO_DEXAMETHASONE | MSigDB lists | GO_RESPONSE_TO_DEXAMETHASONE | 33 | 9 | 15632 | 1249 |
Ass1,Ccl12,Ptafr,Adrb2,Edn1,Il6,Errfi1,Il1b,Ifnb1 |
| 8.570e-04 | -7.06 | regulation of vascular endothelial growth factor production | biological process | GO:0010574 | 31 | 8 | 20694 | 1406 |
Il6,Hif1a,Ccl2,Adora2b,C3,Ptgs2,Il1b,Il1a |
| 8.570e-04 | -7.06 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological process | GO:0042771 | 31 | 8 | 20694 | 1406 |
Ddit4,Nupr1,Ifi204,Cdkn1a,Pmaip1,Pml,Sirt1,Dyrk2 |
| 8.570e-04 | -7.06 | regulation of inflammatory response to antigenic stimulus | biological process | GO:0002861 | 31 | 8 | 20694 | 1406 |
Tnf,Il12b,Fcgr2b,Il10,Nod2,C3,Fcgr1,Spn |
| 8.570e-04 | -7.06 | natural killer cell activation involved in immune response | biological process | GO:0002323 | 31 | 8 | 20694 | 1406 |
Ifna1,Ifna5,Ifna2,Ifna6,Il12b,Stx11,Ifna4,Ifnb1 |
| 8.570e-04 | -7.06 | dendritic cell differentiation | biological process | GO:0097028 | 31 | 8 | 20694 | 1406 |
Relb,Notch2,Lyn,Batf2,Azi2,Batf,Tnfsf9,Irf4 |
| 8.642e-04 | -7.05 | REACTOME_METABOLISM_OF_CARBOHYDRATES | MSigDB lists | REACTOME_METABOLISM_OF_CARBOHYDRATES | 223 | 32 | 15632 | 1249 |
Agrn,Abcc5,B4galt4,Dse,Eno1,Slc2a1,Sdc2,Chst11,Vcan,Pcx,St3gal3,Tpi1,Sdc1,Pgm1,St3gal6,Gbe1,Sdc4,Pfkfb3,Gpc1,Gys1,Hk3,Eno2,Hk1,Slc9a1,Ext1,Slc25a12,Hk2,St3gal1,Ppp2r1b,Ust,Pfkl,Pgk1 |
| 8.685e-04 | -7.05 | myeloid cell activation involved in immune response | biological process | GO:0002275 | 46 | 10 | 20694 | 1406 |
Cx3cr1,Lyn,Ifnb1,Rasgrp1,Nr4a3,Stx11,Prkce,Milr1,Dnase1l3,Syk |
| 8.694e-04 | -7.05 | positive regulation of lipase activity | biological process | GO:0060193 | 54 | 11 | 20694 | 1406 |
Nr1h3,Ccl5,Rhoc,Sele,Lpar1,Ptafr,Flt1,Pdgfrb,Htr2b,Arf4,Htr2a |
| 8.694e-04 | -7.05 | negative regulation of chemotaxis | biological process | GO:0050922 | 54 | 11 | 20694 | 1406 |
Gpr18,Stap1,Sema4c,Dusp1,Ccl12,Notch1,Sema4a,Ptpn2,Sema3c,Thbs1,Slamf8 |
| 8.694e-04 | -7.05 | endothelial cell development | biological process | GO:0001885 | 54 | 11 | 20694 | 1406 |
Col18a1,Ezr,Myadm,Rap2c,Icam1,Rapgef2,Plod3,Clic4,F11r,Met,Myd88 |
| 8.707e-04 | -7.05 | CD20 | pfam domains | PF04103 | 23 | 7 | 18711 | 1348 |
Tmem176b,Ms4a4b,Ms4a4c,Ms4a6b,Ms4a6d,Ms4a6c,Tmem176a |
| 8.707e-04 | -7.05 | Rhodanese | pfam domains | PF00581 | 23 | 7 | 18711 | 1348 |
Dusp6,Dusp4,Dusp16,Dusp8,Dusp5,Dusp2,Dusp1 |
| 8.746e-04 | -7.04 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_PEPTIDE_ANTIGEN | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_PEPTIDE_ANTIGEN | 21 | 7 | 15632 | 1249 |
H2-Q7,H2-Q4,H2-Q6,Tap2,Abcb1a,Tap1,Tapbp |
| 8.746e-04 | -7.04 | ONO_FOXP3_TARGETS_UP | MSigDB lists | ONO_FOXP3_TARGETS_UP | 21 | 7 | 15632 | 1249 |
Slamf7,Cd38,Mecp2,Gadd45b,Il10,Fos,Jun |
| 8.746e-04 | -7.04 | BIOCARTA_P53HYPOXIA_PATHWAY | MSigDB lists | BIOCARTA_P53HYPOXIA_PATHWAY | 21 | 7 | 15632 | 1249 |
Atm,Hif1a,Abcb1a,Nfkbib,Mdm2,Cdkn1a,Nqo1 |
| 8.746e-04 | -7.04 | PID_S1P_S1P1_PATHWAY | MSigDB lists | PID_S1P_S1P1_PATHWAY | 21 | 7 | 15632 | 1249 |
Sphk1,Pdgfrb,Ptgs2,Itgav,Abcc1,Kdr,Pdgfb |
| 8.746e-04 | -7.04 | GO_NEGATIVE_REGULATION_OF_VIRAL_TRANSCRIPTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_VIRAL_TRANSCRIPTION | 21 | 7 | 15632 | 1249 |
Jun,Trim13,Ccl5,Hdac1,Ccl4,Trim21,Trim14 |
| 8.746e-04 | -7.04 | GO_NECROPTOTIC_PROCESS | MSigDB lists | GO_NECROPTOTIC_PROCESS | 21 | 7 | 15632 | 1249 |
Ripk3,Mlkl,Birc2,Tnf,Fas,Tlr3,Cd14 |
| 8.746e-04 | -7.04 | BIOCARTA_MITOCHONDRIA_PATHWAY | MSigDB lists | BIOCARTA_MITOCHONDRIA_PATHWAY | 21 | 7 | 15632 | 1249 |
Birc2,Casp8,Birc3,Casp7,Apaf1,Cycs,Casp3 |
| 8.752e-04 | -7.04 | regulation of GTPase activity | biological process | GO:0043087 | 430 | 47 | 20694 | 1406 |
Map4k4,Rapgef2,Cdc42ep2,Map2k1,Rgs3,Dock10,Lrch1,Abr,Ccl22,Rgs14,Rgs1,Ranbp2,Rap1gap2,Rin2,Crkl,Tbc1d13,Htr2b,F11r,Asap3,Rictor,Ccl2,Rasgrp1,Ccl12,Sh3bp4,Ric1,Ccl4,Jun,Arhgap26,Cx3cl1,Ccl7,Ccl3,Ccl8,Bcl6,Tbc1d1,Agrn,Ccl9,Cd40,Sipa1l1,Elmod2,Adap2,Spry2,Tagap,Ccl5,Dennd1b,Pkp4,Dock4,Icam1 |
| 8.782e-04 | -7.04 | GSE43863_NAIVE_VS_TH1_EFF_CD4_TCELL_D6_LCMV_DN | MSigDB lists | GSE43863_NAIVE_VS_TH1_EFF_CD4_TCELL_D6_LCMV_DN | 125 | 21 | 15632 | 1249 |
Rtp4,Rnd1,Ppm1l,Ddx58,Trib1,Pgs1,Sp110,Trafd1,Epsti1,Casp8,Cd274,Tap2,Fzd5,Gch1,Ccl5,Tnf,Nod2,Sele,Psme2,Ube2l6,Isg20 |
| 8.797e-04 | -7.04 | negative regulation of cell cycle | biological process | GO:0045786 | 407 | 45 | 20694 | 1406 |
Ier3,Gpr132,Btg2,Mdm2,Hhex,Notch1,Pttg1,Casp3,Ccnd1,Osm,Inhba,Tnfaip3,Whamm,Thbs1,Timeless,Plk2,Map2k1,Bmp2,Casp2,Lif,Atm,Ptgs2,Myc,Il12b,Tmem67,Rbl1,Trip13,Rgcc,Nupr1,Kat2b,Cdkn2d,Notch2,Irf1,Nr4a1,Ccl12,Hinfp,Pml,Cdkn1a,Plaat3,Cenpe,Dcun1d3,Pnpt1,Slfn1,Plk3,Tnf |
| 8.803e-04 | -7.04 | DNA-binding transcription activator activity | molecular function | GO:0001216 | 445 | 49 | 20217 | 1400 |
Tfec,Mycl,Nr4a3,Plagl2,Fos,Etv6,Ier2,Mafg,Nr1h3,Nr4a1,Sirt1,Hmga1,Plscr1,Rel,Egr2,Relb,Irf4,Hif1a,Etv5,Stat4,Tcf4,Lhx2,Pou2f2,Stat5a,Fubp1,Batf,Nfkb2,Spic,Hmga2,Stat1,Jun,Myc,Csrnp1,Stat3,Nr3c1,Irf1,Hivep2,Junb,Klf7,Stat2,Klf6,Fosb,Plagl1,Pbx1,Nfkb1,Cebpd,Egr1,Notch1,Irf2 |
| 8.803e-04 | -7.04 | DNA-binding transcription activator activity, RNA polymerase II-specific | molecular function | GO:0001228 | 445 | 49 | 20217 | 1400 |
Nr1h3,Mafg,Nr4a1,Sirt1,Ier2,Fos,Etv6,Mycl,Tfec,Plagl2,Nr4a3,Fubp1,Stat5a,Pou2f2,Batf,Nfkb2,Spic,Hmga2,Tcf4,Lhx2,Irf4,Relb,Hif1a,Stat4,Etv5,Plscr1,Hmga1,Egr2,Rel,Klf7,Stat2,Nr3c1,Irf1,Hivep2,Junb,Jun,Myc,Csrnp1,Stat3,Stat1,Notch1,Irf2,Cebpd,Egr1,Fosb,Plagl1,Pbx1,Nfkb1,Klf6 |
| 8.863e-04 | -7.03 | CAIRO_HEPATOBLASTOMA_DN | MSigDB lists | CAIRO_HEPATOBLASTOMA_DN | 242 | 34 | 15632 | 1249 |
Hp,Zc3h12a,Trib1,Slc43a3,Acsl1,Inpp1,Rcl1,Nfil3,Nampt,Mfap3l,Gch1,Marco,C1rl,Serpine1,Ext1,Alas1,Slpi,Kmo,Papss2,St3gal6,Il4ra,Rnd3,Cd14,Dnase1l3,Tsku,Klf6,Ass1,Ets2,Fcgr2b,Cp,Stard5,Gadd45g,Cxcl14,C1ra |
| 8.869e-04 | -7.03 | GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN | MSigDB lists | GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN | 151 | 24 | 15632 | 1249 |
Nfkb2,Rgs1,Clcn7,Znrf1,Stat1,Zc3h7a,Gpr132,Xaf1,Cd69,Sesn3,Dusp6,Nampt,Fosb,Relb,Zc3hav1,Malt1,Traf1,Gbp3,Gbp9,Gbp4,Myc,Dock10,Nlrc5,Nr4a1 |
| 8.869e-04 | -7.03 | KATSANOU_ELAVL1_TARGETS_UP | MSigDB lists | KATSANOU_ELAVL1_TARGETS_UP | 151 | 24 | 15632 | 1249 |
Il2rg,Cd200,Pcgf5,Esd,Slfn3,Plekha2,Plod2,Slfn4,Dusp6,Gdf15,Slamf9,Psme2,Pdgfb,Nupr1,Fas,Lpcat2,Spsb1,Ccng2,Pde5a,Nfkbie,Ifi44,Sat1,Irgm2,Ctsc |
| 8.869e-04 | -7.03 | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_UP | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_UP | 151 | 24 | 15632 | 1249 |
Slc43a3,Fam162a,Sh3bgrl2,Lap3,Plek,Tor3a,Hivep3,Trip13,Csf1,Inpp5b,Ociad1,Reps1,Arrdc4,Marcksl1,Psme1,Plagl2,Me1,Ppfibp1,Cd38,Spred1,Batf,Tank,Cst7,Itgb8 |
| 8.873e-04 | -7.03 | renal system vasculature development | biological process | GO:0061437 | 18 | 6 | 20694 | 1406 |
Angpt1,Notch1,Pdgfrb,Egr1,Pdgfb,Notch2 |
| 8.873e-04 | -7.03 | interleukin-1 beta production | biological process | GO:0032611 | 18 | 6 | 20694 | 1406 |
Casp1,Aim2,Il1b,Nlrp3,Tlr6,Nlrc4 |
| 8.873e-04 | -7.03 | kidney vasculature development | biological process | GO:0061440 | 18 | 6 | 20694 | 1406 |
Notch2,Pdgfb,Pdgfrb,Egr1,Angpt1,Notch1 |
| 8.873e-04 | -7.03 | regulation of podosome assembly | biological process | GO:0071801 | 18 | 6 | 20694 | 1406 |
Fscn1,Src,Hck,Palld,Kif9,Tnf |
| 8.897e-04 | -7.02 | GO_POST_EMBRYONIC_DEVELOPMENT | MSigDB lists | GO_POST_EMBRYONIC_DEVELOPMENT | 84 | 16 | 15632 | 1249 |
Tal2,Plagl2,Csrnp1,Prdm1,Arid5b,Chst11,Kdm5b,Mecp2,Bcl2l11,Morc3,Serp1,Tiparp,Fzd5,Tet2,Sema3c,Itpr1 |
| 8.897e-04 | -7.02 | BONCI_TARGETS_OF_MIR15A_AND_MIR16_1 | MSigDB lists | BONCI_TARGETS_OF_MIR15A_AND_MIR16_1 | 84 | 16 | 15632 | 1249 |
Kpna3,Crkl,Dnaja2,Plagl1,Pim1,Ccnd2,Cdk5r1,Map2k4,Trim36,Ccne1,Ptch1,Kcnj2,Akt3,Btg2,Ccnd1,Cpd |
| 8.919e-04 | -7.02 | TNF_1 | prosite domains | PS00251 | 11 | 5 | 13278 | 1037 |
Tnfsf4,Tnfsf9,Tnfsf10,Tnf,Tnfsf8 |
| 8.919e-04 | -7.02 | WH1 | prosite domains | PS50229 | 11 | 5 | 13278 | 1037 |
Evl,Vasp,Homer1,Spred3,Spred1 |
| 8.919e-04 | -7.02 | GO_PHAGOCYTIC_VESICLE | MSigDB lists | GO_PHAGOCYTIC_VESICLE | 92 | 17 | 15632 | 1249 |
Rab20,Tlr2,Tlr6,Tlr9,H2-Q7,Stx6,Rab9,Rab11fip1,Tlr1,Irgm2,Rab10,Inpp5b,H2-Q6,Itgav,Syk,H2-Q4,Rab32 |
| 8.922e-04 | -7.02 | RAGHAVACHARI_PLATELET_SPECIFIC_GENES | MSigDB lists | RAGHAVACHARI_PLATELET_SPECIFIC_GENES | 61 | 13 | 15632 | 1249 |
Gng11,Thbs1,Prkar2b,Pf4,Snn,Tnfsf4,Endod1,Max,Odc1,Mmd,Tuba4a,Ccl5,Mfap3l |
| 8.987e-04 | -7.01 | Regulation by c-FLIP | REACTOME pathways | R-MMU-3371378 | 10 | 5 | 8608 | 757 |
Cflar,Fas,Tnfsf10,Casp8,Traf2 |
| 8.987e-04 | -7.01 | Dimerization of procaspase-8 | REACTOME pathways | R-MMU-69416 | 10 | 5 | 8608 | 757 |
Tnfsf10,Fas,Cflar,Casp8,Traf2 |
| 8.987e-04 | -7.01 | CASP8 activity is inhibited | REACTOME pathways | R-MMU-5218900 | 10 | 5 | 8608 | 757 |
Casp8,Traf2,Tnfsf10,Fas,Cflar |
| 8.987e-04 | -7.01 | Ligand-dependent caspase activation | REACTOME pathways | R-MMU-140534 | 10 | 5 | 8608 | 757 |
Traf2,Casp8,Tnfsf10,Cflar,Fas |
| 8.987e-04 | -7.01 | Interleukin-6 signaling | REACTOME pathways | R-MMU-1059683 | 10 | 5 | 8608 | 757 |
Stat1,Jak2,Il6,Stat3,Socs3 |
| 9.032e-04 | -7.01 | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | MSigDB lists | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | 160 | 25 | 15632 | 1249 |
Bcl2a1d,Gadd45g,Rin2,Tnfsf8,Egr2,Il6,Fos,Tspan3,Bcl2a1b,Cd83,Sgk3,Ciapin1,Fam133b,Prnp,Zfp36,Phlda1,Plk2,Tnfsf14,Dach1,Il1b,Armc8,Agpat4,Bcl2a1a,Dusp5,Egr3 |
| 9.032e-04 | -7.01 | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | MSigDB lists | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | 160 | 25 | 15632 | 1249 |
Usp31,Rcan1,Chic2,Fosb,Rapgef2,Maff,Met,Atf3,Egr1,Bcor,Cx3cl1,St3gal6,Rnd3,Ncoa7,Spred1,Slc25a37,Dusp1,Sod2,Tagln,Fos,Tnc,Itgb8,Cp,Rbpms,Mid1 |
| 9.041e-04 | -7.01 | RPL9 (ribosomal protein L9) | protein interactions | 6133 | 3 | 3 | 7778 | 753 |
Ksr1,Rrbp1,Mdm2 |
| 9.041e-04 | -7.01 | Hist2h3c1 (histone cluster 2, H3c1) | protein interactions | 15077 | 3 | 3 | 7778 | 753 |
Cxcl10,Il6,Cxcl2 |
| 9.041e-04 | -7.01 | Odc1 (ornithine decarboxylase, structural 1) | protein interactions | 18263 | 3 | 3 | 7778 | 753 |
Nqo1,Odc1,Myc |
| 9.049e-04 | -7.01 | actin-based cell projection | cellular component | GO:0098858 | 208 | 27 | 20747 | 1409 |
Triobp,Myo10,Angpt1,Ezr,Palld,Spn,Rhoc,Acpp,Dync1h1,Myo1b,Cnp,Cd302,Itgav,Vasp,Clic5,Clic4,Pdpn,Kitl,Slc4a7,Fchsd2,Spata13,Fscn1,Vcam1,Syne2,Dock4,Cyfip1,Antxr1 |
| 9.095e-04 | -7.00 | mRNA catabolic process | biological process | GO:0006402 | 117 | 18 | 20694 | 1406 |
Tent2,Atm,Tent4a,Helz2,Xrn1,Zhx2,Magohb,Pnpt1,Tut7,Gtpbp2,Dcp2,Dcp1a,Zc3h12a,Zfp36,Noct,Polr2g,Smg7,Ago3 |
| 9.098e-04 | -7.00 | Pkinase_Tyr | pfam domains | PF07714 | 129 | 20 | 18711 | 1348 |
Src,Pdgfrb,Axl,Lyn,Fgr,Mlkl,Syk,Jak2,Flt1,Igf1r,Acvrl1,Met,Ksr1,Hck,Kdr,Acvr1,Tyk2,Ripk3,Ptk2,Ripk2 |
| 9.099e-04 | -7.00 | WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1 | MSigDB lists | WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1 | 27 | 8 | 15632 | 1249 |
Tpi1,Trib3,Higd1a,Slc2a1,Eno1,Egln3,Olr1,Pgk1 |
| 9.099e-04 | -7.00 | KAMIKUBO_MYELOID_CEBPA_NETWORK | MSigDB lists | KAMIKUBO_MYELOID_CEBPA_NETWORK | 27 | 8 | 15632 | 1249 |
Irf8,Hdc,Lcn2,Il18,S100a8,Hp,Glrx,Spint2 |
| 9.099e-04 | -7.00 | GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS_IN_CYCLIC_AMIDINES | MSigDB lists | GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS_IN_CYCLIC_AMIDINES | 27 | 8 | 15632 | 1249 |
Mthfd2,Mthfd1l,Apobec3,Gch1,Gda,Adar,Ampd3,Zbp1 |
| 9.099e-04 | -7.00 | GO_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION | MSigDB lists | GO_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION | 27 | 8 | 15632 | 1249 |
Tap1,Nod2,Thbs1,Abcb1a,Nod1,Tapbpl,Tap2,Cd74 |
| 9.099e-04 | -7.00 | WOTTON_RUNX_TARGETS_DN | MSigDB lists | WOTTON_RUNX_TARGETS_DN | 27 | 8 | 15632 | 1249 |
Kitl,Nr3c1,Cebpd,Egln3,Errfi1,Fndc3a,Eno2,Plod2 |
| 9.105e-04 | -7.00 | regulation of response to DNA damage stimulus | biological process | GO:2001020 | 208 | 27 | 20694 | 1406 |
Fbxo4,Plscr1,Timeless,Eya4,Pml,Spred1,Eef1e1,Atm,Parp9,Sirt1,Ier3,Dtx3l,Myc,Mdm2,Spred3,Cgas,Cd74,Pmaip1,Parp3,Ppp4r2,Fignl2,Kmt5a,Spire1,Dek,Psmd10,Cdkn2d,Radx |
| 9.106e-04 | -7.00 | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | 448 | 55 | 15632 | 1249 |
Lmo4,Pid1,Tor3a,Plscr1,Asb13,Rcsd1,Mthfd2,Sema4a,Endod1,Gsta3,Ppfibp2,Tiparp,Cited2,B4galt4,Plac8,Ezr,H2-Q4,Nfkbia,Gadd45g,Nqo1,Pla2g4a,Edn1,Mpp7,Mul1,Cyth3,Dusp14,Aff1,Pnpt1,Gclc,Rras2,Sipa1l1,Hopx,Dusp6,Nampt,Slc31a2,Hsd17b12,Tapbpl,St3gal1,Smox,Abcc4,Ptges,Gng12,Cd302,H2-Q6,Insl6,Stat5a,Hspa2,Cebpd,Errfi1,Ly75,D1Ertd622e,Calcrl,H2-Q7,Pdgfc,Rab3ip |
| 9.125e-04 | -7.00 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_DN | 169 | 26 | 15632 | 1249 |
Eif4g2,Dgka,Kctd12,Sap30,St7,Ldha,Kpna3,Sec24a,Notch2,Cited2,Jun,Csf3r,Casz1,N4bp1,Dusp1,Klf6,Pde5a,Ifnb1,Ifrd1,Pnp2,Egr1,Atf3,Ahr,Zbp1,Cd14,Ciita |
| 9.125e-04 | -7.00 | GSE28130_ACTIVATED_VS_INDUCEED_TREG_DN | MSigDB lists | GSE28130_ACTIVATED_VS_INDUCEED_TREG_DN | 169 | 26 | 15632 | 1249 |
Tnfrsf1b,Dach1,Irf7,Hopx,Ddit4,Tmeff1,Adora2a,Cxcl2,Stx11,Smpdl3b,Il13ra1,Dusp5,Dck,Hmox1,Nr4a3,Cxcl1,Cacna1d,Lhx2,Fcgr2b,Ccnd1,Aldh1b1,Dmxl2,Tspo,Gpc1,Crlf3,Zbtb5 |
| 9.126e-04 | -7.00 | regulation of blood circulation | biological process | GO:1903522 | 240 | 30 | 20694 | 1406 |
Jak2,Edn1,Gja1,Cav1,Icam1,Dock4,Ahr,Htr2a,Mdm2,Pde5a,Pde4b,Sirt1,Zc3h12a,Agrn,Pdgfb,Atp2b4,Scn1b,Ptafr,Hif1a,Cacna1d,Ptgs2,Cx3cl1,Hopx,Adrb2,Slc9a1,Cd38,Dusp5,Kcnj2,Map2k1,Gch1 |
| 9.134e-04 | -7.00 | GSE339_CD8POS_VS_CD4CD8DN_DC_DN | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_DN | 187 | 28 | 15632 | 1249 |
Prnp,Fgr,Nck1,Ifit1,Cd164,Rgs3,Relb,Crlf3,Rgs14,Arhgef3,Cyfip1,Ddhd1,Aebp2,Abcb1a,Ptgs2,Rcl1,Rel,Lcp2,Myo1b,Mov10,Map2k1,Hdc,Junb,Rgl1,Gch1,Nfkb1,Ccrl2,Htra1 |
| 9.134e-04 | -7.00 | GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_DN | MSigDB lists | GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_DN | 187 | 28 | 15632 | 1249 |
Fosb,Pdgfrb,Asns,Gja1,Eno2,Cxcl2,Cnn3,Cdc42ep4,Dnajb4,Hmox1,C3,Hp,Ptges,Dusp16,Ikbke,Birc2,Agrn,Spryd7,P4ha2,Cpd,Sele,Errfi1,Edn1,F11r,Trim13,Col18a1,Ch25h,Slc25a25 |
| 9.134e-04 | -7.00 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP | 187 | 28 | 15632 | 1249 |
Tapbp,Mid1,Gbp4,Gbp9,Dbnl,Arid5a,Ifit1bl1,Stau1,Gda,Gnb4,Pou2f2,Syne2,Tbc1d13,Slc7a5,Cysltr2,Csf1,Irf7,Lgals9,Ifit1bl2,Cmpk2,Trafd1,Pkp4,Cxcl10,Mthfd2,Nsmaf,Tgfbi,Clec5a,Sema4c |
| 9.134e-04 | -7.00 | GSE18203_CTRL_VS_INTRATUMORAL_CPG_INJ_MC38_TUMOR_DN | MSigDB lists | GSE18203_CTRL_VS_INTRATUMORAL_CPG_INJ_MC38_TUMOR_DN | 187 | 28 | 15632 | 1249 |
Marcksl1,Hif1a,Plagl1,Prnp,Sass6,Tpx2,Cd83,Prdx1,Mdfic,Gadd45b,Plac8,Casp1,Bcl2a1b,Cyfip1,Bcl6,Casp3,Tnfsf8,Bcl2a1d,Odc1,Ttc39b,Bcl2a1a,Adam19,Cldnd1,Pgk1,Hopx,Casp4,Mmd,Egln3 |
| 9.154e-04 | -7.00 | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN | MSigDB lists | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN | 540 | 64 | 15632 | 1249 |
Isg20,Psmb8,Pdk3,Nfkb1,Lap3,Cflar,Arf4,Tax1bp1,Vrk2,Nfil3,Casp7,Etnk1,Ppa1,Odc1,Acsl1,Nat2,Ap3b1,Optn,Syk,Sqstm1,Jun,Dnaja1,Slamf7,Pde3b,Prpf4,Fas,Nck1,Trim13,Ube2l6,Btg2,G3bp2,Oas2,Hsd17b12,Cdyl,Pde4b,Med21,Map2k1,Atp6v1d,Gtpbp2,Tnfsf10,Sec24b,Ppp2r2a,Dusp5,Ak4,Stat3,Pnp2,Rab9,Rhoq,Klf6,Txnrd1,Slc16a3,Itpr1,Psmb9,Oas3,Cd40,Birc2,Myd88,Crlf3,Gys1,Cd38,Cd164,Irf2,Rhoh,Rnf139 |
| 9.157e-04 | -7.00 | GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | MSigDB lists | GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | 178 | 27 | 15632 | 1249 |
Ifi204,Ebi3,Trafd1,Keap1,Pfkl,Lrp11,Osbpl3,Mndal,Map2k1,Layn,Psd4,P4ha1,Psmb8,Ifi203,Egln3,Spint2,Ccdc25,Ifi208,Ifi211,Ifi214,Apaf1,Ifi207,Ifi209,Ifi205,Mrpl52,Ifi213,Ap3b1 |
| 9.157e-04 | -7.00 | GSE18893_CTRL_VS_TNF_TREATED_TREG_24H_UP | MSigDB lists | GSE18893_CTRL_VS_TNF_TREATED_TREG_24H_UP | 178 | 27 | 15632 | 1249 |
Rap2c,Irak2,Idi1,Slfn3,Arf4,Dusp16,Dusp5,Uchl1,Ep400,Srxn1,Parp12,Adora2a,Gch1,Ifit1bl2,Rabgef1,Hdc,Slfn4,Gys1,Col4a2,Olr1,Slc30a1,Samd9l,Mdm2,4932438A13Rik,Gypc,Ifit1bl1,Psmb9 |
| 9.157e-04 | -7.00 | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_DN | MSigDB lists | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_DN | 178 | 27 | 15632 | 1249 |
Fam111a,Nsmaf,Gpd2,Sema4c,Casp7,Ptgir,Hmox1,Cdkn1a,Abcc4,Glrx,Clic4,Il10,Car13,Mmd,Pdss1,Hif1a,Ubash3b,Ifih1,Tpi1,Spred1,Dusp14,Gnb4,Rapgef5,Gsr,Cpd,Dusp4,Carhsp1 |
| 9.157e-04 | -7.00 | GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_UP | 178 | 27 | 15632 | 1249 |
Spic,Plod3,Bcl2l11,Itgav,Cish,Mmp14,Ly75,Egr2,Ifih1,Il1a,Hif1a,Cyth3,Prdm1,Ahr,Ptch1,Il10,Csrp1,Slc4a7,Ccrl2,Plscr1,Ddit4,Csf1,Gpd2,Ptprj,Xcr1,Clic4,Il1rn |
| 9.157e-04 | -7.00 | GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_DN | MSigDB lists | GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_DN | 178 | 27 | 15632 | 1249 |
Bbx,Slfn8,Gsr,Ift57,Dusp1,Dock4,Lipg,Rnf34,Myo10,Cd38,Apaf1,Ext1,Icosl,Stx11,4930523C07Rik,Slc13a3,Serpine1,Adap2,Slfn9,Arf4,Elmod2,Filip1l,Itga5,Tnfsf4,Il18,Mefv,Phyh |
| 9.169e-04 | -6.99 | BZIP_BASIC | prosite domains | PS00036 | 34 | 9 | 13278 | 1037 |
Nfil3,Batf2,Jun,Jdp2,Fosb,Atf3,Batf,Junb,Fos |
| 9.202e-04 | -6.99 | GO_RESPONSE_TO_ALKALOID | MSigDB lists | GO_RESPONSE_TO_ALKALOID | 134 | 22 | 15632 | 1249 |
Hif1a,Icam1,Htr2a,Plau,Slc7a11,Tnf,Psmb9,Homer1,Il6,Prkce,Edn1,Casp3,Sdc2,Mdm2,Hmox1,Vcam1,Ppp2r2a,Il1b,Nfkb1,Ccl5,Fosb,Ppp1r15a |
| 9.202e-04 | -6.99 | LANDIS_ERBB2_BREAST_TUMORS_324_UP | MSigDB lists | LANDIS_ERBB2_BREAST_TUMORS_324_UP | 134 | 22 | 15632 | 1249 |
Flnb,St3gal5,Rab10,Lmo4,Lcn2,Csrp1,Dusp6,Cd82,Ier3,Ell2,Dck,Etnk1,Errfi1,Ccnd1,Ctsc,Fut8,Serp1,Ptpn2,Ezr,Nr4a1,F11r,Ier2 |
| 9.223e-04 | -6.99 | GO_ACTIN_FILAMENT_BASED_PROCESS | MSigDB lists | GO_ACTIN_FILAMENT_BASED_PROCESS | 408 | 51 | 15632 | 1249 |
Antxr1,Scn1b,Pdlim7,Vasp,Gja1,Plek,Pdgfrb,Sipa1l1,Myo1b,Daam1,Fmnl2,Spire1,Rhoq,Micall2,Arhgap26,Sele,Src,Tnf,Bcl6,Swap70,Rnd1,F11r,Flnb,Cnn3,Slc9a1,Syne2,Rhou,Rictor,Hcls1,Cflar,Whamm,Jak2,Fscn1,Frmd6,Tmod3,Rac3,Kcnj2,Phactr4,Triobp,S1pr2,Ezr,Cnn2,Trip10,Rhof,Zyx,Cdc42ep2,Rnd3,Palld,Evl,Abr,Nck1 |
| 9.226e-04 | -6.99 | GO_FC_EPSILON_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_FC_EPSILON_RECEPTOR_SIGNALING_PATHWAY | 117 | 20 | 15632 | 1249 |
Jun,Lcp2,Psmb9,Fos,Psmd10,Syk,Ikbkg,Nfkb1,Psmb8,Nfkbia,Psma6,Psme2,Nr4a3,Psmb10,Lyn,Map2k4,Tab2,Psmb6,Psme1,Malt1 |
| 9.226e-04 | -6.99 | KRAS.BREAST_UP.V1_UP | MSigDB lists | KRAS.BREAST_UP.V1_UP | 117 | 20 | 15632 | 1249 |
Gfi1,Glrx,Tnfaip3,Il1b,Pde3b,Cxcl1,Cmklr1,Traf1,Il2rg,Ccl22,Mmp9,Lif,Prdm1,Cxcl2,Tmem176a,Spry2,Acpp,Ppp1r15a,Dhrs9,Birc3 |
| 9.243e-04 | -6.99 | Antifolate resistance | KEGG pathways | ko01523 | 30 | 9 | 7931 | 713 |
Mthfr,Abcc5,Ikbkg,Il6,Il1b,Abcc4,Tnf,Abcc1,Nfkb1 |
| 9.243e-04 | -6.99 | Antifolate resistance | KEGG pathways | mmu01523 | 30 | 9 | 7931 | 713 |
Il6,Ikbkg,Mthfr,Abcc5,Il1b,Abcc4,Tnf,Nfkb1,Abcc1 |
| 9.257e-04 | -6.98 | GO_REGULATION_OF_LIPID_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_LIPID_METABOLIC_PROCESS | 271 | 37 | 15632 | 1249 |
Fabp3,Fgr,Irs2,Nr1h3,Pde3b,Bmp2,Htr2a,Tspo,Rbl1,Flt1,Tnf,Src,Pik3r5,Pla2g4a,Prkce,Ppp2r5a,Nod2,Ptk2,C3,Ptgs2,Trib3,Adrb2,Nr4a3,Nsmaf,Lyn,Ldlr,Gfi1,Htr2b,Il1b,Hcar2,Pdk3,Nfkb1,Cav1,Pdgfrb,Pik3r6,Pdgfb,Sirt1 |
| 9.291e-04 | -6.98 | protein tyrosine/serine/threonine phosphatase activity | molecular function | GO:0008138 | 38 | 9 | 20217 | 1400 |
Dusp4,Dusp14,Dusp1,Dusp28,Dusp6,Dusp8,Dusp2,Dusp16,Dusp5 |
| 9.312e-04 | -6.98 | Integrin cell surface interactions | REACTOME pathways | R-MMU-216083 | 63 | 14 | 8608 | 757 |
Itgav,Kdr,Itga5,F11r,Vcam1,Itgb8,Tnc,Icam1,Itga9,Itgal,Thbs1,Itga4,Col18a1,Col4a2 |
| 9.375e-04 | -6.97 | plasma membrane bounded cell projection organization | biological process | GO:0120036 | 1055 | 98 | 20694 | 1406 |
Kif5c,Cenpj,Tnc,Mecp2,Pdpn,Adora2a,Ehd1,Evl,Intu,Sdc2,Ezr,Cnp,Tsku,Ntng2,Triobp,S1pr2,Lrp8,Fas,Carmil1,Igsf9,Flrt2,Itga4,Rac3,Clic5,Nectin2,Rab3ip,Ptk2,Rilpl1,Scn1b,Dst,Lrp4,Lpar1,Sema3c,Map4k4,Map2k1,Dock10,Micall2,Hap1,Lst1,Snx10,Jak2,Flrt3,Crkl,Abcc4,Scarf1,Notch1,Stxbp1,Egr2,Kdr,Atp6v1d,Snx2,P2ry12,Jun,Fnbp1l,Nck1,Ift57,Sdc4,Fcgr2b,Spata13,Ext1,Tmem67,Igf1r,Psd,Ccl5,Rab10,Uchl1,Actb,Rpgrip1l,Fscn1,Sec24b,Ift22,Agrn,Mark2,Il6,Cyfip1,Ttc39c,Phgdh,Vasp,Whamm,Prnp,Plek,Nrp2,Rapgef2,Lhx2,Sema4a,Dnaaf3,Ptch1,Gja1,Casp3,Dbnl,Nr4a3,Cdk5r1,Spire1,Klf7,Lyn,Palld,Btg2,Arf4 |
| 9.384e-04 | -6.97 | GO_POSITIVE_REGULATION_OF_CELL_CYCLE | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_CYCLE | 300 | 40 | 15632 | 1249 |
Hspa2,Ccnd1,Cnot4,Mdm2,Prkce,Edn1,Cited2,Ankrd17,Psmd10,Bcl2l11,Src,Tnks1bp1,Pbx1,Crlf3,Cdk5r1,Sphk1,Il1a,Phip,Plagl1,Ccnd2,Pml,Plk3,Casp2,Ube2e2,Pdgfb,Trim21,Btg2,Pdgfrb,Cenpj,Plk2,Asns,Atm,Cdkn1a,Il1b,Pkp4,Nr4a3,Pim1,Tmod3,Smc5,Prdm9 |
| 9.419e-04 | -6.97 | LI_LUNG_CANCER | MSigDB lists | LI_LUNG_CANCER | 40 | 10 | 15632 | 1249 |
Prdx1,Pgk1,Hap1,Hck,Mdm2,Nfkb1,Psmb6,Ccne1,Hp,Fgr |
| 9.419e-04 | -6.97 | BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN | MSigDB lists | BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN | 40 | 10 | 15632 | 1249 |
Rcn1,Ak4,Higd1a,Eno1,Pdk3,Hmgcs1,Psat1,Stat5a,Plac8,Tax1bp1 |
| 9.419e-04 | -6.97 | KAAB_FAILED_HEART_VENTRICLE_DN | MSigDB lists | KAAB_FAILED_HEART_VENTRICLE_DN | 40 | 10 | 15632 | 1249 |
Psme2,Cd14,Rab9,Stat3,Wars,Slc39a14,Ldha,Slc31a2,Isg15,Daam1 |
| 9.419e-04 | -6.97 | PID_IFNG_PATHWAY | MSigDB lists | PID_IFNG_PATHWAY | 40 | 10 | 15632 | 1249 |
Jak2,Stat3,Il1b,Crkl,Stat1,Casp1,Irf1,Map2k1,Socs1,Ptpn2 |
| 9.419e-04 | -6.97 | GO_REGULATION_OF_INTERLEUKIN_10_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_10_PRODUCTION | 40 | 10 | 15632 | 1249 |
Cd34,Irf4,Cd83,Nod2,Ptger4,Tlr9,Tnfsf4,H2-Eb1,Cd274,Il12b |
| 9.419e-04 | -6.97 | RASHI_RESPONSE_TO_IONIZING_RADIATION_1 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_1 | 40 | 10 | 15632 | 1249 |
Egr1,Dusp1,Atf3,Ier2,Slc2a1,Adrb2,Jun,Ier3,Fos,Zfp36 |
| 9.423e-04 | -6.97 | BORLAK_LIVER_CANCER_EGF_UP | MSigDB lists | BORLAK_LIVER_CANCER_EGF_UP | 54 | 12 | 15632 | 1249 |
Fos,Serpine1,Ets2,Atf3,Junb,Tlr6,Egr1,Fgl2,Ccnd1,Rhoc,Btg2,Plscr1 |
| 9.489e-04 | -6.96 | Chuk (conserved helix-loop-helix ubiquitous kinase) | protein interactions | 12675 | 18 | 7 | 7778 | 753 |
Tax1bp1,Nfkbib,Rnf31,Cd40,Ikbkg,Nfkbia,Tpx2 |
| 9.512e-04 | -6.96 | nucleolus | cellular component | GO:0005730 | 830 | 80 | 20747 | 1409 |
Tcea1,Ifi203,Rcl1,Myo10,Pml,Ifi208,Cutc,Pdk3,Acsl5,Kdm4a,Phlda1,Ifi211,Crbn,Riox2,Mcm10,Tent4a,Wdr43,Tulp3,Mdm2,Trib3,Phf6,Noc4l,Atf3,Stat1,Adar,Fam111a,N4bp1,Hmox1,Mdfic,Parp10,Mdn1,Ifi214,Pim1,Nfkbie,Cdkn1a,Plscr1,Ccdc86,Parp3,Ezr,Mtdh,Plk3,Malt1,Ptk2,Oasl1,Pcgf5,Rabgef1,Jmjd6,Isg20,Ifi209,Sbds,Golga3,Snapc1,Ifi205,Eef1e1,Itpr1,Rai14,Ifi204,Taf4b,Sertad3,Rgcc,Ccnd2,Txnrd1,Tra2a,Etv6,Arid5a,Ifi213,Myc,Prdx1,Mtus1,Tma16,Mndal,Atm,Rrs1,Sp140,Ciapin1,Klf6,Ifi207,Dock4,Rsad2,Arl4a |
| 9.523e-04 | -6.96 | GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 143 | 23 | 15632 | 1249 |
Mafg,Rtp4,Il12b,Plk3,Egr3,Dnaja2,Gng4,Uchl1,Daxx,Il15ra,Idi1,Kdr,Homer1,Ets2,Fam43a,Tmem200b,Srm,Tor1aip2,Plscr1,Piezo1,Katna1,Slc2a6,Slc39a4 |
| 9.525e-04 | -6.96 | cellular macromolecule catabolic process | biological process | GO:0044265 | 731 | 72 | 20694 | 1406 |
Dnajb2,Uchl1,Zhx2,Tmem67,Birc2,Xrn1,Tent2,Cnot4,Cop1,Rnf19b,Psmb10,Zfp36,Dcp1a,Psmb6,Oas2,Dtx3l,Bnip3,Pnpt1,Magohb,Rffl,Usp42,Rnf34,Znrf3,Armc8,Uba7,Ago3,Pml,Casp8,Psmb8,Noct,Klhl25,Arrdc4,Rnf19a,Dcp2,Gtpbp2,Psmb9,Bfar,Keap1,Tnfaip3,Crbn,Helz2,Usp18,Znrf1,Isg15,Chmp4b,Polr2g,Trim13,Rnf139,Sirt1,Zc3h12a,Spsb1,Arel1,Dnase1l3,Mdm2,Ankib1,Rnf14,Psma6,Gpc1,Usp12,Tent4a,Atm,Usp25,Rnaset2a,Ctsc,Smg7,Ubr4,Isg20,Fbxo4,Peli1,Ube2l6,Slfn8,Tut7 |
| 9.548e-04 | -6.95 | YTATTTTNR_MEF2_02 | MSigDB lists | YTATTTTNR_MEF2_02 | 624 | 72 | 15632 | 1249 |
Cdkn1a,Lrrc8c,Prkar2b,Dnajb2,Tmem67,Rgs1,Rap2c,Rab20,Lyn,Max,Trim14,Med13,Il10,Vezt,Sik3,Clic5,P4ha1,Cd34,Sgcb,Gng11,Plagl1,Mpp7,Ppm1l,Palld,Usp25,Mllt6,Dtnb,Edn1,Mmp14,Znfx1,Fos,Trip10,Jun,Klf3,Nr4a1,Gadd45b,Adhfe1,Flrt3,Bcl2l11,Zhx2,Ppp2r2a,Tnfsf10,Kcna3,Lox,Frmd4a,Ppp2r3a,Nrp2,Sipa1l1,Rrs1,Fosb,Junb,Slc7a8,Rgl1,Plagl2,Gnb4,Cd180,Zfp281,Slc39a13,Slc30a4,Hlx,Prdm1,Arhgap26,Ccnd1,Prdx5,B3gnt5,Rab21,Ntng2,Rffl,Rnf24,Rhoq,P2ry12,Bcl6 |
| 9.565e-04 | -6.95 | LEE_BMP2_TARGETS_DN | MSigDB lists | LEE_BMP2_TARGETS_DN | 804 | 89 | 15632 | 1249 |
Bambi,Ptgs2,Serpinb9,Larp1,Usp31,Ldha,Dnaja2,Hk2,Noc4l,Fubp1,Mthfd1l,Jarid2,Nampt,Gch1,Ahsa1,Bmp2,Jmjd6,Mcm10,Mdn1,Fut8,Ly75,Ccdc86,Tank,Ehd1,Hsph1,Spryd7,Tnfaip2,Fam111a,Etnk1,Ppa1,Dck,Eef1e1,Hat1,Rasgrp1,Pdss1,Trip13,Psat1,Ccne1,Angpt1,Rras2,Rnd3,Pnpt1,Pde3b,Taf4b,Tra2a,Cxcl14,Rab32,Stip1,Pgk1,Cox18,Adora2b,Mcm6,Naa25,Tlr3,Asns,Cacybp,Rrs1,Serpine1,Cdyl,Gja1,Pdgfc,Irak3,Sav1,Ube2f,Csrnp1,Hdac1,Cycs,Phgdh,P4ha2,Slc16a3,Usp53,Txnrd1,Wdr43,Hsd17b7,Fscn1,Idi1,Ppp2r1b,Ldlr,Odc1,Mthfd2,Cnn3,S100a8,Me1,Pim3,Slc16a1,Ciapin1,Ifrd1,Ass1,Srm |
| 9.572e-04 | -6.95 | GGGTGGRR_PAX4_03 | MSigDB lists | GGGTGGRR_PAX4_03 | 1185 | 124 | 15632 | 1249 |
Agpat4,Plekhn1,Nlgn2,Armc8,Prkar2b,Sh3bgrl2,Cacna1d,Tnip1,Irf1,Slc39a14,Procr,Ptch1,Pdk3,Eif4g2,Eno2,Lnpep,Mark2,Tnks1bp1,Rbms2,Ccnd2,Abr,Kremen1,Spry2,Prkce,Ppp2r5a,Il6,Jun,Flt1,Map3k6,Zhx2,Pim1,Kif3c,Cd55,Dusp5,Adora2a,Maff,Hk2,Pdgfb,Daam1,Gch1,Tuba4a,Crim1,Mcmbp,Hif1a,Socs1,Sphk1,Psme1,Hhex,Apba1,Mthfr,Lif,Zfp513,Acvr1,Zfp800,Nr3c1,Fut8,Dusp8,Fchsd2,Rgs14,Dync1h1,Axl,Clmp,Cdkn1a,Notch2,Egr3,Max,Sema4c,Pim2,Itga5,Usp12,Kctd12,Zeb1,Spen,Slc9a1,Mov10,Dcun1d3,Klf7,Rbl1,Ahr,Zbtb5,Gmppb,Cnot4,Vcan,Psd,Mllt6,Scarf1,Tor1aip2,Hmga1,Nr4a1,Gadd45b,Klf3,Sqstm1,Ptges,Plat,Nr4a3,Gpr85,Frmd4a,Il2rg,Pcgf5,Ddit4,Rab10,Col11a2,Plekha4,Serpine1,Brd2,Brwd3,Cd38,Etv5,Gnb4,Ube2f,Pbx1,Klf8,Tab2,Pigv,Prdm1,Arhgap26,Treml2,Hdac1,Stat3,Slc39a4,Homer1,Mtus1,Tcf4,Slc25a37 |
| 9.608e-04 | -6.95 | cellular response to DNA damage stimulus | biological process | GO:0006974 | 658 | 66 | 20694 | 1406 |
Bcl2l11,Tank,Dyrk2,Bcl2a1a,Tnks1bp1,Timeless,Samhd1,Marf1,Tlk2,Casp2,Zbtb5,Nek6,Atm,Smc5,Ikbke,Bcl2a1d,Mcm9,Parp9,Sirt1,Ier3,Zc3h12a,Tnfrsf1b,Btg2,Mdm2,Hmga2,Pmaip1,Mcm6,Mapkapk2,Pttg1,Ikbkg,Casp3,Susd6,Uaca,Mcm10,Hmox1,Ccnd1,Lyn,Batf,Uba7,Parp10,Ddit4,Eya4,Hinfp,Asf1a,Pml,Rbbp8,Cdkn1a,Bcl2a1b,Hspa1a,Ifi204,Tnf,Plk3,Ascc3,Egln3,Sod2,Myc,Bcl6,Dtx3l,Cgas,Parp3,Dnaja1,Trip13,Ube2e2,Nupr1,Hmga1,Cdkn2d |
| 9.614e-04 | -6.95 | COATES_MACROPHAGE_M1_VS_M2_DN | MSigDB lists | COATES_MACROPHAGE_M1_VS_M2_DN | 69 | 14 | 15632 | 1249 |
Tlr1,Bnip3,Procr,Egln3,Bst1,Il18bp,Gdf15,Slc2a1,Hspa1a,Flrt2,Thbs1,Rras2,F10,Uchl1 |
| 9.614e-04 | -6.95 | GO_ENDODERM_DEVELOPMENT | MSigDB lists | GO_ENDODERM_DEVELOPMENT | 69 | 14 | 15632 | 1249 |
Inhba,Dusp4,Ext1,Mmp14,Dusp2,Dusp1,Itgav,Notch1,Col4a2,Hhex,Itga4,Dusp5,Itga5,Mmp9 |
| 9.614e-04 | -6.95 | RAMALHO_STEMNESS_DN | MSigDB lists | RAMALHO_STEMNESS_DN | 69 | 14 | 15632 | 1249 |
Hdc,Col11a2,Rgs14,Slfn4,Ppp2r5a,Acvrl1,Cebpd,Abr,Evl,St3gal6,Papss2,Arg2,Grina,Slfn3 |
| 9.617e-04 | -6.95 | NOD1/2 Signaling Pathway | REACTOME pathways | R-MMU-168638 | 25 | 8 | 8608 | 757 |
Irak2,Nod1,Ripk2,Nod2,Casp8,Ikbkg,Tnfaip3,Tab2 |
| 9.655e-04 | -6.94 | gland development | biological process | GO:0048732 | 432 | 47 | 20694 | 1406 |
Igf1r,Csf1,Irs2,Notch2,Pdgfrb,Arid5b,Rpgrip1l,Kdm5b,Tnc,Cited2,Tnf,Stat5a,Jun,Sod2,Ikzf1,Met,Plaur,Pml,Jak2,Gja1,Lmo4,Itpr1,Ptch1,Crkl,Hmox1,Ripk3,Ahr,Pbx1,Ccnd1,Cav1,Hhex,Notch1,Hmga2,Tet2,Hp,Hif1a,Pdgfb,Atm,Il6,Hlx,Src,Bcl2l11,Nr3c1,Sema3c,Map2k1,Bmp2,Jarid2 |
| 9.665e-04 | -6.94 | positive regulation of Ras protein signal transduction | biological process | GO:0046579 | 63 | 12 | 20694 | 1406 |
Pdgfrb,Gpr35,Map4k4,Map2k1,Notch1,Rasgrp1,Prag1,Csf1,Gpr18,Kitl,Notch2,Lpar1 |
| 9.753e-04 | -6.93 | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP | 152 | 24 | 15632 | 1249 |
Smg7,Gclc,Prdx1,Gbe1,C1ra,Ifrd1,Ubtd2,Spryd7,Sbds,Slc16a3,Slc25a37,Eif2ak2,P4ha2,Sp110,Vcam1,Gfpt1,Phyh,Ms4a6d,Slc25a12,Htra1,Hdc,Med21,Casp4,Cav1 |
| 9.753e-04 | -6.93 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_UP | 152 | 24 | 15632 | 1249 |
Snn,Kcna3,Tgfbi,Shisa3,Rhou,Hk2,Zeb1,Cysltr2,Clic5,Mthfd1l,Pde4b,Nfkb1,Ahr,Tab2,Traf1,Dusp4,Spry2,Mdn1,Tnfsf8,Myc,Hmga1,Spsb1,Hivep2,Plekha5 |
| 9.776e-04 | -6.93 | neural tube development | biological process | GO:0021915 | 188 | 25 | 20694 | 1406 |
Notch1,Mthfd1l,Rpgrip1l,Sec24b,Plod3,Ptch1,Lmo4,Casp3,Spint2,Sema4c,Intu,Sdc4,Casp8,Sema3c,Lhx2,Ift57,Apaf1,Phgdh,Vasp,Fzd1,Mthfr,Hif1a,Cited2,Phactr4,Tulp3 |
| 9.808e-04 | -6.93 | MHC class I protein binding | molecular function | GO:0042288 | 18 | 6 | 20217 | 1400 |
Pilra,Pilrb1,Tap1,Pilrb2,Tap2,Klrk1 |
| 9.808e-04 | -6.93 | phosphatidylinositol 3-kinase regulator activity | molecular function | GO:0035014 | 18 | 6 | 20217 | 1400 |
Socs7,Cish,Pik3r6,Socs1,Socs3,Pik3r5 |
| 9.856e-04 | -6.92 | BENPORATH_CYCLING_GENES | MSigDB lists | BENPORATH_CYCLING_GENES | 583 | 68 | 15632 | 1249 |
Rgs3,Tsku,Bmp2,Kdm4a,Hif1a,Zfp281,Tab2,Kmo,Ccnd1,Kdm5b,Mdm2,Nr3c1,Casp3,Top3a,Itpr1,Timp1,Gpsm2,Rbbp8,Birc2,Klf6,Txnrd1,Usp53,Vegfc,Vcam1,Rcan1,Osgin2,Mcm6,Cdc42ep4,Larp1,Sap30,Antxr1,Plk2,Ifit1bl2,Gdf15,Tle3,Olr1,Pttg1,Sdc1,Cyth3,Kat2b,Arl4a,Dmxl2,Tpx2,Cdkn2d,Il18bp,Tra2a,Ncoa5,Dusp4,Mid1,Cxcl14,Gclm,Katna1,Znfx1,Ifit1bl1,Cnn2,Cenpe,Ap3m2,Cflar,Dr1,Dnajb4,Pik3cd,Ebi3,Uaca,Stat1,Met,Trip13,Lmo4,Ccne1 |
| 9.900e-04 | -6.92 | GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP | 161 | 25 | 15632 | 1249 |
Hivep2,Rab21,Ift57,Dusp4,Nod2,Ifrd1,Malt1,Sell,Traf5,Irak3,Ccr1,Cd86,Rel,Flnb,Wdfy1,Cnn3,Mtmr14,Ptk2,Ier3,Irf1,Tgfbi,Cldnd1,Arf4,Snn,Esd |
| 9.914e-04 | -6.92 | SHIN_B_CELL_LYMPHOMA_CLUSTER_6 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_6 | 11 | 5 | 15632 | 1249 |
Ptgs2,Socs1,Ifnb1,Il1b,S100a8 |
| 9.914e-04 | -6.92 | REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 | MSigDB lists | REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 | 11 | 5 | 15632 | 1249 |
Ddx58,Rnf135,Ifih1,Casp8,Ikbkg |
| 9.914e-04 | -6.92 | MARTINELLI_IMMATURE_NEUTROPHIL_DN | MSigDB lists | MARTINELLI_IMMATURE_NEUTROPHIL_DN | 11 | 5 | 15632 | 1249 |
Sema3c,Csf3r,Fcgr4,Aoah,Sod2 |
| 9.914e-04 | -6.92 | GO_POSITIVE_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_POSITIVE_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 11 | 5 | 15632 | 1249 |
Stat3,Pdgfb,Jun,Hif1a,Fos |
| 9.914e-04 | -6.92 | GO_REGULATION_OF_CHEMOKINE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CHEMOKINE_BIOSYNTHETIC_PROCESS | 11 | 5 | 15632 | 1249 |
Il1b,Hmox1,Il6,Tlr3,Tnf |
| 9.914e-04 | -6.92 | BIOCARTA_MONOCYTE_PATHWAY | MSigDB lists | BIOCARTA_MONOCYTE_PATHWAY | 11 | 5 | 15632 | 1249 |
Sell,Sele,Itgal,Icam1,Itga4 |
| 9.914e-04 | -6.92 | MODULE_528 | MSigDB lists | MODULE_528 | 11 | 5 | 15632 | 1249 |
Asns,Lap3,Acsl1,Gclm,Gclc |
| 9.914e-04 | -6.92 | GO_CD40_RECEPTOR_COMPLEX | MSigDB lists | GO_CD40_RECEPTOR_COMPLEX | 11 | 5 | 15632 | 1249 |
Traf5,Rnf31,Traf2,Birc2,Cd40 |
| 9.914e-04 | -6.92 | ST_STAT3_PATHWAY | MSigDB lists | ST_STAT3_PATHWAY | 11 | 5 | 15632 | 1249 |
Il6,Cish,Src,Jak2,Stat3 |
| 9.914e-04 | -6.92 | WU_HBX_TARGETS_1_UP | MSigDB lists | WU_HBX_TARGETS_1_UP | 11 | 5 | 15632 | 1249 |
Il6,Fas,Glrx,Acp2,Casp4 |
| 9.914e-04 | -6.92 | BIOCARTA_GLYCOLYSIS_PATHWAY | MSigDB lists | BIOCARTA_GLYCOLYSIS_PATHWAY | 11 | 5 | 15632 | 1249 |
Pgk1,Eno1,Pfkl,Hk1,Tpi1 |
| 9.914e-04 | -6.92 | regulation of hormone biosynthetic process | biological process | GO:0046885 | 39 | 9 | 20694 | 1406 |
Nfkb1,Gfi1,Bmp2,Il1b,Tnf,Egr1,Igf1r,Nr3c1,Hif1a |
| 9.920e-04 | -6.92 | regulation of hormone secretion | biological process | GO:0046883 | 296 | 35 | 20694 | 1406 |
Nos2,Tnf,Cacna1d,Rab11fip1,Hif1a,Ptger4,Lif,Pde3b,Il6,Glrx,Serp1,Map4k4,Cd38,Gpr68,Hdac1,Hcar2,Prkce,Hmgn3,Clcf1,Ccl5,Osm,Irs2,Slc16a1,Klf7,Inhba,Jak2,Edn1,Gja1,Pfkl,Nlgn2,Hmga2,Pim3,Il1b,Kdm5b,Sirt1 |
| 9.923e-04 | -6.92 | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | MSigDB lists | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | 101 | 18 | 15632 | 1249 |
Fcho2,Ier3,Cxcl10,Pmepa1,Vcpip1,Idi1,Ikbke,Clic4,Slc48a1,Plat,Asns,Serpine1,Tnfrsf1b,Cpd,Dusp4,Tbc1d1,Ddit4,Pdlim7 |
| 9.927e-04 | -6.92 | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | 253 | 35 | 15632 | 1249 |
Rai14,Spry2,Dusp4,Plod3,Ehd1,Cutc,Rnd3,Prdx1,Col4a2,Prpf4,Palld,Pttg1,Upp1,Pdlim7,Trip13,Timeless,Phlda1,Flnb,Eef1e1,Hat1,Dusp6,Map4k4,Txn1,Ldlr,Idi1,Arf4,Gfpt1,Actb,Ppp2r2a,Pgk1,Igf2bp2,Plaur,Ldha,Mcm6,Odc1 |
| 9.935e-04 | -6.91 | GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_DN | MSigDB lists | GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_DN | 188 | 28 | 15632 | 1249 |
Mrpl52,Ccnd1,Mllt6,Rhoq,Irf4,Phgdh,P2ry14,Upp1,Tpi1,Prpf4,Spred1,Cd38,Lipg,Pim3,Gnb4,Cd274,Smpdl3b,Nrp2,Serpinb9,Pik3cd,Rtn1,Endod1,Wdr43,Igf2bp2,Fam20c,Serpinb2,Ccl4,Jak2 |
| 9.935e-04 | -6.91 | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_UP | MSigDB lists | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_UP | 188 | 28 | 15632 | 1249 |
Odc1,Trib1,Hmox1,Fndc3a,Keap1,Gfpt1,Jag1,Flnb,Jmjd6,Gbe1,Tpi1,Mapkapk2,Rhoc,Gclc,Tspo,Fos,Cd302,Mgat1,Jun,Hmga1,Ezr,Dusp1,Txnrd1,Sqstm1,Acvr1,Nqo1,Gsr,Gclm |
| 9.935e-04 | -6.91 | GSE3982_EOSINOPHIL_VS_DC_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_DC_DN | 188 | 28 | 15632 | 1249 |
Nqo1,Cers6,Mdm2,Slc15a3,Rai14,Pnp2,Ctsc,Eno1,Dhrs9,Flt1,Samhd1,Sdc4,Cd83,Kmo,Palld,Atf3,Ppp2r3a,Slc39a14,Bst1,H2-Aa,Trim14,Adap2,Fam162a,Osbpl3,Il1rn,Cxcl1,Tgfbi,Slc31a1 |
| 9.935e-04 | -6.91 | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_17H_DN | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_17H_DN | 188 | 28 | 15632 | 1249 |
Tspan3,Treml2,Chst11,Dusp4,Pnp2,Tle3,Irak3,Mcmbp,Gnb4,Lpcat2,Flrt2,Plekhg1,Rnaset2a,Myadm,Snx2,Hk2,Egln3,Piezo1,Tlr1,Aida,Larp1,Fam53c,Smox,Usp31,Rnaset2b,Ccl4,Cldnd1,Irak2 |
| 9.935e-04 | -6.91 | GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_DN | MSigDB lists | GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_DN | 188 | 28 | 15632 | 1249 |
Jarid2,Ogfr,Plk2,Maff,Cxcl2,St3gal1,Rab20,Trib3,Bambi,Nfil3,Il1b,Bcl2l11,Dusp1,Nr4a1,Hspa1a,Fos,Rai14,Cish,Phgdh,Tlk2,Ogfrl1,Mafk,Mthfr,Atf3,Pttg1,Il1a,Pilra,Crim1 |
| 9.945e-04 | -6.91 | regulation of metal ion transport | biological process | GO:0010959 | 421 | 46 | 20694 | 1406 |
Glrx,Ccl12,Mllt6,Ccr1,Pml,Gpr35,Slc30a1,Tlr9,Adrb2,Slc9a1,Adora2a,Cx3cl1,Cxcl1,Tspo,Cacna1d,P2ry12,Ccl4,Ubash3b,Atp2b4,Agrn,Pdgfrb,Htr2a,Pde4b,Icam1,Ccl5,Serpine1,Homer1,Hspa2,Gem,Kcnj2,Hap1,Stoml1,Prnp,Cacnb3,Ptgs2,Cxcl10,Pdgfb,Scn1b,Akt3,Slc31a2,Prkce,Ahr,Lyn,Cav1,Itpr1,Gja1 |
| 9.973e-04 | -6.91 | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP | MSigDB lists | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP | 170 | 26 | 15632 | 1249 |
Maff,Zfp36,Slc7a5,Med21,Plk2,Birc3,Rgs1,St7,Asb13,Osgin2,Itga5,Filip1l,Rtn1,Ptger4,Ift57,Cpd,Ifrd1,Abcb1a,Dse,Hsph1,Tnf,Olr1,Dnase1l3,Tnfaip3,Jmjd6,Etv3 |
| 9.982e-04 | -6.91 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_DN | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_DN | 179 | 27 | 15632 | 1249 |
Adora2a,Isg20,Csf1,St3gal5,Tnfsf14,Dcun1d3,Gch1,Rnf31,Il15ra,Dusp16,Rsbn1,Tnfsf10,Serpinb9,Ptafr,Cpeb4,Hmox1,Traf3ip2,Dtx2,Scarf1,Timp1,Casp1,Zc3hav1,Bfar,Myd88,Sla,Rtp4,Hhex |
| 9.982e-04 | -6.91 | GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 179 | 27 | 15632 | 1249 |
Psma6,Peli1,Psmd10,Psmb9,Birc2,Angpt1,Fbxo4,Arrdc4,Sphk1,Mul1,Psmb10,Malt1,Ube2e1,Psme1,Rnf139,Nmi,Psme2,Cav1,Psmb8,Birc3,Dcun1d3,Dnajb2,Trib3,Adrb2,Ptk2,Ripk2,Psmb6 |
| 9.982e-04 | -6.91 | GO_EPITHELIAL_CELL_DEVELOPMENT | MSigDB lists | GO_EPITHELIAL_CELL_DEVELOPMENT | 179 | 27 | 15632 | 1249 |
Plod3,Ezr,Notch1,Icam1,Sdc1,Hif1a,F11r,Palld,Col18a1,Prdm1,Met,Rapgef2,Jag1,Flnb,Pdgfb,Rilpl1,Myadm,Gja1,Slc4a7,Clic5,Arid4a,Cdkn1a,Frmd6,Sec24b,Clic4,Rap2c,Fndc3a |
| 9.982e-04 | -6.91 | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN | 179 | 27 | 15632 | 1249 |
Fpr1,Pim1,Dnajb2,Il1b,Igf1r,Gng12,Dusp6,Pde4b,Ccr1,Plk2,Slpi,Hhex,Evl,Sell,Prnp,Ccnd2,Nkiras1,Abcc5,Parp8,Tpst1,Tcf4,Bcl6,Cd40,Fcgr2b,Tapbp,Rin2,Cnot4 |
| 9.982e-04 | -6.91 | GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | MSigDB lists | GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | 179 | 27 | 15632 | 1249 |
Hvcn1,Crim1,Ppfibp1,Tnfaip3,Me1,Clec4e,Pde3b,Cd180,Nlrp3,Slco3a1,Tlr6,Fgl2,I830077J02Rik,Peli1,Slc44a1,Csf3r,Zyx,Dhrs9,Tnfaip2,Tgfbi,Rcsd1,Fam111a,Ptprj,Il13ra1,Rtn1,Stat4,Pde7b |
| 1.001e-03 | -6.91 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | MSigDB lists | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | 77 | 15 | 15632 | 1249 |
Ptk2,Itga5,Icam1,Itga9,F11r,Vcam1,Col4a2,Thbs1,Src,Syk,Itgav,Itgal,Tnc,Itgb8,Rasgrp1 |
| 1.001e-03 | -6.91 | GO_REGULATION_OF_JUN_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_JUN_KINASE_ACTIVITY | 77 | 15 | 15632 | 1249 |
Map3k6,Tnf,Syk,Traf2,Fzd5,Dnaja1,Edn1,Dbnl,Tlr9,Tlr6,Aida,Mul1,Daxx,Mdfic,Il1b |
| 1.003e-03 | -6.91 | BCL2RLATEDA1 | prints domains | PR01867 | 4 | 3 | 5821 | 374 |
Bcl2a1a,Bcl2a1d,Bcl2a1b |
| 1.005e-03 | -6.90 | cyclin-dependent protein serine/threonine kinase regulator activity | molecular function | GO:0016538 | 46 | 10 | 20217 | 1400 |
Ccng2,Ccnd1,Ccnd2,Casp3,Cdk5r1,Ccnj,Cdkn1a,Cdkn2d,Kat2b,Ccne1 |
| 1.006e-03 | -6.90 | fat cell differentiation | biological process | GO:0045444 | 118 | 18 | 20694 | 1406 |
Egr2,Socs7,Ero1l,Nr4a3,Ptgs2,Ccnd1,Arl4a,Socs1,Sirt1,Cebpd,Arid5b,Adrb2,Lrrc8c,Plac8,Bnip3,4932438A13Rik,Nr4a1,Psmb8 |
| 1.012e-03 | -6.90 | MODULE_170 | MSigDB lists | MODULE_170 | 93 | 17 | 15632 | 1249 |
Cebpd,Kctd12,Ccr1,Ccl12,Ccl5,Timp1,Pdgfrb,Vcam1,Tnfsf10,Thbs1,Cd14,Fcgr1,Gbp2,Mmp9,Ccnd2,Ier3,Fpr1 |
| 1.012e-03 | -6.90 | MODULE_172 | MSigDB lists | MODULE_172 | 93 | 17 | 15632 | 1249 |
Hp,Hmgcs1,Mmp9,Plau,F10,Plat,Olr1,Casp1,Timp1,Psmb9,Lap3,Casp4,Ctsc,Mmp14,Mmp13,Pla2g7,C1ra |
| 1.014e-03 | -6.89 | somatodendritic compartment | cellular component | GO:0036477 | 1020 | 95 | 20747 | 1409 |
Grk3,Cnn3,Htr2a,Nqo1,Casp3,Psd,Cdk5r1,Cd200,Magohb,Ldlr,Cx3cr1,Cpeb4,Glrx,Sdc2,Uchl1,Slc31a1,Bnip3,Xrn1,Prnp,Arf4,Pde4b,Ass1,Mark2,Palld,Dync1h1,Adora2a,Hdc,Plk2,Prkar2b,Eno2,Txnrd1,Tnfrsf1b,Igf1r,Casp4,Cx3cl1,Ccr1,Tnf,Fcgr2b,Myo10,Nr3c1,Map2k1,Pdgfb,Kif3c,Mul1,Katna1,Ctla2a,Lpar1,Adrb2,Map2k4,Stau1,Sipa1l1,Tpx2,Lrp8,Igsf9,Ccl2,Stat1,Gpc1,Rgs14,Optn,Lrp4,Rapgef2,Apba1,Kremen1,Cd40,Fscn1,Homer1,Hdac1,Kif5c,Itga4,Ptch1,Cyfip1,Flnb,Plk3,Rab3ip,Htr2b,Ptk2,Kdr,Hap1,Cacna1d,Ift57,Rac3,Dbnl,Itpr1,Met,Dock10,Fas,Max,Pde1b,Nlgn2,Acvrl1,Fabp7,Ptger4,Ero1l,Kcnj2,Txn1 |
| 1.016e-03 | -6.89 | HOEBEKE_LYMPHOID_STEM_CELL_DN | MSigDB lists | HOEBEKE_LYMPHOID_STEM_CELL_DN | 85 | 16 | 15632 | 1249 |
Ifi214,Ifi204,Phyh,Tnfsf10,Il1b,Etv5,Ifi207,Ifi213,Mndal,Ifi209,Ifi205,Klf2,Ifi208,Ifi211,Maff,Ifi203 |
| 1.016e-03 | -6.89 | BIOCARTA_MAPK_PATHWAY | MSigDB lists | BIOCARTA_MAPK_PATHWAY | 85 | 16 | 15632 | 1249 |
Map2k1,Jun,Traf2,Fos,Nfkb1,Map4k4,Nfkbia,Map3k6,Rapgef2,Myc,Map2k4,Map3k8,Mapkapk2,Stat1,Max,Daxx |
| 1.016e-03 | -6.89 | GNF2_STAT6 | MSigDB lists | GNF2_STAT6 | 85 | 16 | 15632 | 1249 |
Casp4,Serp1,Rnaset2a,H2-Q6,Junb,Psmb8,H2-Q4,Tyk2,Tapbp,Sell,Psmb10,Lyn,H2-Q7,Rnaset2b,Hcls1,Myd88 |
| 1.018e-03 | -6.89 | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_DN | 135 | 22 | 15632 | 1249 |
Pla2g7,Usp12,Nfkbie,Acvrl1,Vasp,Axl,Cst7,Osbpl3,Pilra,Hcls1,Rgs1,Pmepa1,Dnase1l3,Olfml3,Abr,Tgfbi,Cd74,Ccl22,Itga9,Spata5l1,Dmxl2,Il12b |
| 1.018e-03 | -6.89 | MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP | MSigDB lists | MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP | 360 | 46 | 15632 | 1249 |
Uaca,Oasl1,Mtdh,Mafg,Odc1,Tnfaip2,Abcc1,Prkar2b,Ahrr,Etv6,Mmd,Pgs1,Ppm1l,Sdc1,Slc48a1,Gclc,Gpc1,Prpf4,Srm,Ass1,Bbx,Pdpn,Gclm,Pcx,Nqo1,Vcan,Fam53c,Naa25,Gng12,Brd2,Ccl5,Map4k4,G3bp2,Marcksl1,Rnd1,Slco3a1,Myd88,Myo10,Mcmbp,Txnrd1,Hspa1a,Ttc39c,Traf2,Slc15a3,Gsr,Nfkbie |
| 1.020e-03 | -6.89 | regulation of immunoglobulin production | biological process | GO:0002637 | 72 | 13 | 20694 | 1406 |
Clcf1,Tnf,Il4ra,Tnfaip3,Traf2,Cd40,Il6,Tnfsf4,Fcgr2b,Cgas,Parp3,Tlr9,Bcl6 |
| 1.022e-03 | -6.89 | REACTOME_INFLAMMASOMES | MSigDB lists | REACTOME_INFLAMMASOMES | 16 | 6 | 15632 | 1249 |
Aim2,Txn1,Casp1,Nlrc4,Nlrp3,Mefv |
| 1.022e-03 | -6.89 | KIM_PTEN_TARGETS_UP | MSigDB lists | KIM_PTEN_TARGETS_UP | 16 | 6 | 15632 | 1249 |
Fam162a,Cdkn1a,Plau,Slc7a11,Ifi44,Gdf15 |
| 1.022e-03 | -6.89 | FINETTI_BREAST_CANCER_KINOME_GREEN | MSigDB lists | FINETTI_BREAST_CANCER_KINOME_GREEN | 16 | 6 | 15632 | 1249 |
Hck,Mlkl,Lyn,Fgr,Pim2,Syk |
| 1.022e-03 | -6.89 | BIOCARTA_PML_PATHWAY | MSigDB lists | BIOCARTA_PML_PATHWAY | 16 | 6 | 15632 | 1249 |
Tnf,Fas,Tnfrsf1b,Pml,Sirt1,Daxx |
| 1.022e-03 | -6.89 | GO_CELLULAR_RESPONSE_TO_ANTIBIOTIC | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ANTIBIOTIC | 16 | 6 | 15632 | 1249 |
Il1b,Ppp1r15a,Mdm2,Pla2g4a,Rab10,Slc9a1 |
| 1.022e-03 | -6.89 | YIH_RESPONSE_TO_ARSENITE_C4 | MSigDB lists | YIH_RESPONSE_TO_ARSENITE_C4 | 16 | 6 | 15632 | 1249 |
Nck1,Map3k8,Jun,F11r,Tapbp,Etv6 |
| 1.022e-03 | -6.89 | BIOCARTA_P53_PATHWAY | MSigDB lists | BIOCARTA_P53_PATHWAY | 16 | 6 | 15632 | 1249 |
Atm,Ccne1,Ccnd1,Apaf1,Mdm2,Cdkn1a |
| 1.022e-03 | -6.89 | GO_HOST | MSigDB lists | GO_HOST | 16 | 6 | 15632 | 1249 |
Ifit1bl1,Axl,Ifit1bl2,Sco1,Tap2,Tap1 |
| 1.022e-03 | -6.89 | GO_CYCLIC_NUCLEOTIDE_CATABOLIC_PROCESS | MSigDB lists | GO_CYCLIC_NUCLEOTIDE_CATABOLIC_PROCESS | 16 | 6 | 15632 | 1249 |
Cnp,Pde5a,Pde7b,Pde4b,Pde3b,Pde1b |
| 1.029e-03 | -6.88 | GO_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING | MSigDB lists | GO_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING | 118 | 20 | 15632 | 1249 |
Txn1,Tnf,Src,Axl,Pik3r5,Rictor,Sirt1,Phlpp1,Csf3,Spry2,Il6,Mul1,Ptk2,Ptprj,Mtdh,Angpt1,F10,Thbs1,Hcls1,Gcnt2 |
| 1.029e-03 | -6.88 | ACACTAC_MIR1423P | MSigDB lists | ACACTAC_MIR1423P | 118 | 20 | 15632 | 1249 |
Tiparp,Pde4b,Slc7a11,Tmem200b,Brwd3,Rnf31,Itgav,Psip1,Rictor,Mmd,Egr2,Kat2b,Tab2,Arid5b,Fndc3a,Spred1,Aff1,Fmnl2,Stau1,Gfi1 |
| 1.037e-03 | -6.87 | GO_CORE_PROMOTER_PROXIMAL_REGION_DNA_BINDING | MSigDB lists | GO_CORE_PROMOTER_PROXIMAL_REGION_DNA_BINDING | 321 | 42 | 15632 | 1249 |
Aebp2,Hdac1,Cebpd,Stat3,Nr3c1,Irf4,Batf2,Myc,Egr2,Fos,Jun,Ets2,Ifi205,Ifi209,Tcf4,Ifi213,Ifi207,Batf,Hinfp,Pbx1,Zfp281,Ifi214,Mxd1,Atf3,Prdm1,Hhex,Ifi203,Etv6,Pou2f2,Ifi211,Ifi208,Fosb,Mndal,Junb,Jdp2,Actb,Nfkb2,Irf1,Ifi204,Nr4a3,Max,Stat1 |
| 1.050e-03 | -6.86 | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN | MSigDB lists | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN | 144 | 23 | 15632 | 1249 |
Il15,Herc3,Lpcat2,Sell,Aim2,Tmem171,Ifi44,Ly75,Peli1,Pkp4,Ust,Fcho2,Odc1,Usp31,Filip1l,Ell2,Akt3,Tnfsf15,Pid1,Lad1,Cd86,Casp4,Myadm |
| 1.050e-03 | -6.86 | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN | MSigDB lists | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN | 144 | 23 | 15632 | 1249 |
Rab3ip,Olfml3,Cyth3,Ccnd2,Znrf3,Sell,Evl,Bcor,Sele,Kdm5b,Treml2,Myc,Klf3,Igf1r,Zhx2,Znrf1,Ikbke,Mppe1,Cd55,Arl5c,Rasgrp1,Bcorl1,Card6 |
| 1.053e-03 | -6.86 | regulation of ubiquitin-dependent protein catabolic process | biological process | GO:2000058 | 148 | 21 | 20694 | 1406 |
Mdm2,Plk2,N4bp1,Rnf19a,Hspa1b,Rnf139,Rnf19b,Cop1,Trib3,Ptk2,Pml,Caml,Tlk2,Gclc,Hspa1a,Trib1,Dnajb2,Plk3,Rnf14,Psmd10,Ankib1 |
| 1.056e-03 | -6.85 | REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION | MSigDB lists | REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION | 235 | 33 | 15632 | 1249 |
Lnpep,Psmb8,Tap2,Ubr4,Psme2,Ube2l6,Trim21,Uba7,Ube2e2,Socs3,Psmb6,Asb13,Keap1,Sec24b,Itgav,Trim36,Spsb1,H2-Q4,H2-Q6,Psmb9,Psmd10,Psma6,H2-Q7,Psme1,Ube2e1,Socs1,Psmb10,Dtx3l,Fbxo4,Ube2f,Fcgr1,Rnf34,Tap1 |
| 1.057e-03 | -6.85 | Cbl (Casitas B-lineage lymphoma) | protein interactions | 12402 | 52 | 13 | 7778 | 753 |
Sla,Fgr,Flt1,Cd40,Tnf,Serpinb9,Hck,Lyn,Pdgfrb,Crkl,Syk,Src,Nck1 |
| 1.062e-03 | -6.85 | Role of LAT2/NTAL/LAB on calcium mobilization | REACTOME pathways | R-MMU-2730905 | 116 | 21 | 8608 | 757 |
Pik3cd,Pdgfrb,Cd86,Syk,Ppp2r1b,Nr4a1,Kitl,Cdkn1a,Ier3,Pdgfb,Mdm2,Met,Phlpp1,Rictor,Src,Lyn,Cd80,Ppp2r5a,Irs2,Trib3,Phlpp2 |
| 1.067e-03 | -6.84 | negative regulation of response to reactive oxygen species | biological process | GO:1901032 | 25 | 7 | 20694 | 1406 |
Il10,Nr4a3,Glrx,Txn1,Hsph1,Hk3,Met |
| 1.067e-03 | -6.84 | negative regulation of hydrogen peroxide-induced cell death | biological process | GO:1903206 | 25 | 7 | 20694 | 1406 |
Hk3,Met,Hsph1,Nr4a3,Glrx,Txn1,Il10 |
| 1.067e-03 | -6.84 | negative regulation of receptor signaling pathway via JAK-STAT | biological process | GO:0046426 | 25 | 7 | 20694 | 1406 |
Ptpn2,Irf1,Socs3,Cav1,Parp14,Socs1,Hmga2 |
| 1.067e-03 | -6.84 | regulation of heterotypic cell-cell adhesion | biological process | GO:0034114 | 25 | 7 | 20694 | 1406 |
Gcnt2,Il1b,Tnf,Il1rn,Myadm,Il10,Tnfaip3 |
| 1.067e-03 | -6.84 | negative regulation of cellular response to drug | biological process | GO:2001039 | 25 | 7 | 20694 | 1406 |
Txn1,Nr4a3,Glrx,Il10,Hk3,Met,Hsph1 |
| 1.067e-03 | -6.84 | detection of biotic stimulus | biological process | GO:0009595 | 25 | 7 | 20694 | 1406 |
Tlr6,Itgav,Tlr2,Nlrc4,Tlr1,Nod1,Nod2 |
| 1.067e-03 | -6.84 | positive regulation of vascular endothelial growth factor production | biological process | GO:0010575 | 25 | 7 | 20694 | 1406 |
C3,Adora2b,Il6,Il1a,Hif1a,Il1b,Ptgs2 |
| 1.067e-03 | -6.84 | positive regulation of mononuclear cell migration | biological process | GO:0071677 | 25 | 7 | 20694 | 1406 |
Serpine1,Fpr2,Pla2g7,Ccr1,Ccl5,Cxcl10,Ccl2 |
| 1.067e-03 | -6.84 | negative regulation of cell aging | biological process | GO:0090344 | 25 | 7 | 20694 | 1406 |
Sirt1,Bcl6,Plk2,Rbl1,Hmga2,Akt3,Nampt |
| 1.067e-03 | -6.84 | neural tube closure | biological process | GO:0001843 | 109 | 17 | 20694 | 1406 |
Vasp,Fzd1,Tulp3,Phactr4,Cited2,Casp3,Mthfr,Lmo4,Ptch1,Sema4c,Spint2,Sdc4,Sec24b,Lhx2,Apaf1,Ift57,Mthfd1l |
| 1.069e-03 | -6.84 | HSR | prosite domains | PS51414 | 7 | 4 | 13278 | 1037 |
Sp140,Sp110,Sp100,A530032D15Rik |
| 1.071e-03 | -6.84 | GSE3720_UNSTIM_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP | MSigDB lists | GSE3720_UNSTIM_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP | 153 | 24 | 15632 | 1249 |
Dgka,Tlr1,Psme2,Plekha2,Lap3,Dusp6,Map4k4,Psmb8,Mthfd1l,Wdr43,Fam162a,Ikbke,Etnk1,Cd55,Tnfsf8,Stap1,Ppp1r14b,Plac8,Batf,Rras2,Rtp4,Sell,Psme1,Evl |
| 1.073e-03 | -6.84 | GO_GOLGI_APPARATUS_PART | MSigDB lists | GO_GOLGI_APPARATUS_PART | 807 | 89 | 15632 | 1249 |
F10,Sdc4,Lpcat2,Gpc1,Sdc1,Cyth3,Pikfyve,Nck1,Vcan,Optn,Cpd,Ctsc,Aftph,Mmp14,B4galt4,Trip10,Pmepa1,Whamm,Notch2,Gbp2b,Ust,Tlr9,Rhou,Stx6,Cav1,Lap3,Pdgfc,Slc39a13,Cd74,Gbp3,Plk3,Glipr2,B3gnt5,Rab21,Rnf24,H2-Q6,Mgat1,Tpst1,Sec24a,Gcnt2,Tlr3,St3gal1,Ext1,Rab10,Gbgt1,H2-Aa,Fzd5,Golga3,Vps54,H2-Eb1,Gja1,Vcpip1,Rnd3,Sgms2,St3gal3,Chst11,Sdc2,Irgm2,Rab32,H2-Q4,Agrn,Rasgrp1,St3gal5,Notch1,Clcn5,Gbp2,Agtrap,St3gal6,H2-Q7,Tapbp,Fut8,Dbnl,Rab9,Rffl,Rhoq,Acpp,Dse,Slc2a1,Ppp6r1,Il15ra,Sec24b,Chic2,Tgfbi,Tapbpl,H2-Ab1,Cd55,Fndc3a,Pdgfb,Myo1b |
| 1.075e-03 | -6.84 | positive regulation of protein complex disassembly | biological process | GO:0043243 | 32 | 8 | 20694 | 1406 |
Tnf,Carmil1,Irgm2,Irgm1,Plek,Bnip3,Adrb2,Igf1r |
| 1.075e-03 | -6.84 | regulation of cellular extravasation | biological process | GO:0002691 | 32 | 8 | 20694 | 1406 |
Abr,Icam1,Ripk3,Il1a,Itga4,Ptger4,Ccl2,Ptafr |
| 1.075e-03 | -6.84 | negative regulation of interferon-gamma production | biological process | GO:0032689 | 32 | 8 | 20694 | 1406 |
Prnp,Zc3h12a,Lgals9,Il10,Nod2,Axl,Cd274,Tnfsf4 |
| 1.080e-03 | -6.83 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_DN | 189 | 28 | 15632 | 1249 |
Spata13,Slc30a4,Ch25h,Cdkn2d,Ifit1,Myd88,1600014C10Rik,Tiparp,Errfi1,Gadd45g,Cebpd,Fcgr2b,Cish,Pik3cd,Map3k8,Socs3,Pim2,Il1rn,Rbms1,Tax1bp1,Plat,Col11a2,Myo1b,Gja1,Tmem176a,Procr,Plscr1,Alas1 |
| 1.080e-03 | -6.83 | GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_UP | MSigDB lists | GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_UP | 189 | 28 | 15632 | 1249 |
Tmem229b,Mefv,Naa25,C3,Nfil3,Lmo4,Lap3,Egln3,Ociad1,Pstpip2,Pdss1,Tifa,Slpi,Slc2a6,Sgms2,Papss2,Aim2,Mapkapk2,Stau1,Hvcn1,Olr1,Hck,Slc16a1,Cx3cr1,Cenpe,Aoah,Plod3,Cers6 |
| 1.080e-03 | -6.83 | GSE43955_1H_VS_42H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_1H_VS_42H_ACT_CD4_TCELL_UP | 189 | 28 | 15632 | 1249 |
Gpr132,Gem,Slc4a7,Brwd3,Gng12,Gfi1,Thbs1,Kcna3,Adrb2,Cdc42ep4,Ptprj,Rtn1,Nfkbie,Cebpd,Nr3c1,Ikzf1,Pdpn,Msr1,Aoah,Rbl1,Dnase1l3,Hinfp,Ube2f,Adar,Papss2,Ier2,Itga4,Rhoh |
| 1.080e-03 | -6.83 | GSE27786_CD4_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_CD4_VS_CD8_TCELL_UP | 189 | 28 | 15632 | 1249 |
Vps54,Casp4,Birc3,Slc4a7,Tnfrsf1b,Rnf19a,Ext1,Plscr1,Ebi3,Igf1r,Gtpbp2,Bcl2a1a,Rgs1,Gca,Itgav,Bcl2a1b,Casp1,Mllt6,Bcl2a1d,Prdx5,Stard5,Prnp,Atp11a,Hif1a,Pttg1,Ppm1l,Itga4,Apba1 |
| 1.080e-03 | -6.83 | mouse chr5 | chromosome location | mouse chr5 | 383 | 39 | 24173 | 1464 |
Rhof,Fzd1,Dr1,Oas1a,Flt1,Gbp4,Cxcl1,Il6,Kdr,Hsph1,Gfi1,Plod3,Oas1g,Cxcl9,Actb,Abcb1a,Aff1,Tlr1,Cd38,Plac8,Tbc1d1,Lap3,Mafk,Fam133b,Cxcl2,Usp42,Uchl1,Golga3,Grk3,Cxcl10,Pgm1,Cyth3,Oas1b,Oas2,Tlr6,Fgl2,Fscn1,Oas3,Bst1 |
| 1.082e-03 | -6.83 | BILBAN_B_CLL_LPL_DN | MSigDB lists | BILBAN_B_CLL_LPL_DN | 34 | 9 | 15632 | 1249 |
Ms4a6d,Fos,Prnp,Ier3,Junb,Dusp1,Fgl2,Glrx,Sat1 |
| 1.082e-03 | -6.83 | GO_RESPONSE_TO_FLUID_SHEAR_STRESS | MSigDB lists | GO_RESPONSE_TO_FLUID_SHEAR_STRESS | 34 | 9 | 15632 | 1249 |
Plau,Mmp13,Src,Gja1,Ass1,Ptgs2,Klf2,Cited2,Pdgfrb |
| 1.084e-03 | -6.83 | REACTOME_MITOTIC_G1_G1_S_PHASES | MSigDB lists | REACTOME_MITOTIC_G1_G1_S_PHASES | 127 | 21 | 15632 | 1249 |
Ccnd1,Hdac1,Psma6,Myc,Psme2,Psmd10,Psmb9,Psmb8,Ccne1,Rbl1,Cdkn1a,Ppp2r2a,Ppp2r1b,Ccnd2,Mcm6,Psmb10,Max,Psme1,Mcm10,Psmb6,Cdkn2d |
| 1.085e-03 | -6.83 | AREB6_04 | MSigDB lists | AREB6_04 | 226 | 32 | 15632 | 1249 |
Pcgf5,Armc8,Pkp4,Igf1r,Pcdh7,Cmklr1,Lmo4,Dusp6,Nfkb1,Junb,Fzd1,Hivep3,Trim14,Magohb,Prdm1,Me1,Plagl2,Olfml3,Klf7,Pde3b,Ciita,Gnb4,Tcf4,Swap70,Slc7a11,Clmp,Rnf24,Fchsd2,Slc44a1,Kcnj2,Edn1,Fut8 |
| 1.087e-03 | -6.82 | GSE27786_LSK_VS_CD8_TCELL_DN | MSigDB lists | GSE27786_LSK_VS_CD8_TCELL_DN | 180 | 27 | 15632 | 1249 |
Psmb10,Slc30a1,Itga4,Lrch3,Mcmbp,Olfml3,Klf7,Zbp1,Eno1,Dpy19l1,Ehd1,Klf3,Prdx5,Aebp2,Mdm2,Errfi1,Slfn8,Cpeb4,Ap3m2,Slc37a3,Slfn9,Ptch1,Hopx,Sesn3,Leng9,Rnf19a,Stat4 |
| 1.087e-03 | -6.82 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP | 180 | 27 | 15632 | 1249 |
Nr4a3,Rcsd1,Ptafr,Larp1,Ppa1,Epsti1,Agpat4,Sec24a,Gbp7,Mthfd1l,P4ha1,Fam72a,Trip13,Plagl1,Hif1a,Prnp,Gbp3,Sell,Il4ra,Atp2b4,Samhd1,Rras2,Trp53i11,Treml2,Phlpp1,Ift57,Dusp4 |
| 1.087e-03 | -6.82 | GO_REGULATION_OF_CALCIUM_ION_TRANSPORT | MSigDB lists | GO_REGULATION_OF_CALCIUM_ION_TRANSPORT | 180 | 27 | 15632 | 1249 |
Pdgfb,Slc9a1,Hap1,Ccr1,Pde4b,Gja1,Ccl5,Cav1,Pdgfrb,Cacna1d,Ccl4,Tlr9,Ptgs2,Cacnb3,Adrb2,Cxcl10,Lyn,Prkce,Hspa2,Ccl12,Homer1,P2ry12,Tspo,Pml,Icam1,Ubash3b,Slc30a1 |
| 1.087e-03 | -6.82 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP | 180 | 27 | 15632 | 1249 |
Gpc1,Atp11b,Tnfaip3,Mxd1,Nfkbiz,Lrp8,Cish,Mdm2,Errfi1,Ift57,Mlkl,Cers6,Spn,Rab32,Slc7a11,Esd,Sema4c,Pim1,Serpinb9,Mcm6,Slc2a6,Maff,Egln3,Slc7a8,Txn1,Itgal,Osm |
| 1.087e-03 | -6.82 | GSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_DN | 180 | 27 | 15632 | 1249 |
Ifi208,Ifi211,Ifi203,Il18rap,Stoml1,Smpdl3b,Atm,Pde4b,Mndal,Hopx,Osbpl3,Xkr8,Ifi204,Cish,Irf4,Nr3c1,Sp140,Parp8,Ifi213,Ezr,Ifi205,Ifi209,Cd38,Ifi207,Bcor,Ifi214,Trim13 |
| 1.087e-03 | -6.82 | GSE6674_ANTI_IGM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP | MSigDB lists | GSE6674_ANTI_IGM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP | 180 | 27 | 15632 | 1249 |
Dgka,Stxbp3,4930523C07Rik,Ttc9c,Card6,Glrx,Inpp1,Tmem229b,Aida,Tapbpl,Ttc39b,Mtmr14,Lztfl1,Parp9,Ppp2r5a,Otud1,Bcl6,Parp8,Apobec3,Tap1,Samhd1,1600014C10Rik,Sla,Spata13,Cyth3,Evl,Fas |
| 1.089e-03 | -6.82 | RIGGI_EWING_SARCOMA_PROGENITOR_UP | MSigDB lists | RIGGI_EWING_SARCOMA_PROGENITOR_UP | 391 | 49 | 15632 | 1249 |
Shisa3,Ptger4,Dusp5,Pcgf5,Ptgs2,Serpinb9,Pcdh7,Bambi,Jarid2,Gch1,Dusp6,Gdf15,Rnaset2a,Cd274,Btg2,Tnfsf15,Mmp13,AA467197,Marcksl1,Itga4,Icam1,Spata13,Kmo,Upp1,Pbx1,Cd14,Hvcn1,Myo10,Olfml3,Tcf4,Tnc,Ifi44,Egr2,Il13ra1,Mmp9,Gpd2,Rnaset2b,Lmo4,Hivep3,Stat4,Jag1,Lrp8,Ccnd2,Atp11b,Fam43a,Flrt3,Fos,Cited2,Ppfia3 |
| 1.089e-03 | -6.82 | GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_DN | MSigDB lists | GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_DN | 171 | 26 | 15632 | 1249 |
Ptprj,Clec5a,Lyn,Sh3bgrl2,Lacc1,5430427O19Rik,Clec4n,Tnfrsf1b,Gna15,Pid1,Irf8,Trim14,Alas1,Kctd12,Tlr6,Ubash3b,Nkiras1,Tnfrsf8,Ccdc88b,Serp1,Ctsc,Ikzf1,Fcgr2b,Nat2,Batf2,Igsf6 |
| 1.089e-03 | -6.82 | GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_DN | MSigDB lists | GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_DN | 171 | 26 | 15632 | 1249 |
Jun,Ctu1,Pikfyve,Stxbp1,Col18a1,Gda,Mdfic,Ppfibp1,Ube2f,Fzd5,Snx10,Ccnj,Psat1,Ccne1,Dcun1d3,Piezo1,Tifa,Pdss1,Osgin2,Rcan1,Ier3,Pdzd11,Pkp4,Dio2,Tfec,Gfpt1 |
| 1.089e-03 | -6.82 | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | 171 | 26 | 15632 | 1249 |
Arid5b,Nr4a3,Herc6,Ptger4,Tagap,Wdr43,Rel,Plek,Sirt1,Kctd12,Ep400,Zfp36,Ubash3b,Hif1a,Slco3a1,Cdk5r1,Nxf1,Ier2,Mapkapk2,Csrnp1,Notch1,Cd83,Gpr18,Dse,Mtus1,Nr4a1 |
| 1.089e-03 | -6.82 | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN | 171 | 26 | 15632 | 1249 |
H2-Ab1,Pdzd11,Nr4a3,Fam20c,Mob3c,Rnf14,Mthfd1l,Mov10,Sco1,Cacybp,Zc3h12c,Isg20,Rhou,Mcoln2,Dtx3l,1600014C10Rik,Ube2f,Mdfic,Daxx,Sqstm1,Plod3,Pla2g4a,Parp9,Hspa2,Rin2,Cnot4 |
| 1.089e-03 | -6.82 | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 171 | 26 | 15632 | 1249 |
Zc3hav1,Tspo,Zbp1,Inpp1,Notch2,Crlf3,Jak2,Acsl1,Rcan1,Oasl1,Xkr8,Aim2,Tapbp,Snx2,Sdc2,Carhsp1,D16Ertd472e,Csf3r,Tor1aip1,Cst7,Card6,S100a8,Junb,Fcgr4,Cx3cr1,Cnn2 |
| 1.098e-03 | -6.81 | G1/S DNA Damage Checkpoints | REACTOME pathways | R-MMU-69615 | 64 | 14 | 8608 | 757 |
Mdm2,Psmb8,Psmb10,Cdkn1a,Psme2,Psma6,Psmd10,Ccne1,Psme2b,Cop1,Atm,Psmb9,Psmb6,Psme1 |
| 1.102e-03 | -6.81 | GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 513 | 61 | 15632 | 1249 |
Micall2,Bcl6,Swap70,Ddhd1,Tnf,Src,Hck,Plagl2,Daxx,Icam1,Hif1a,Il1a,Pml,Lif,Hap1,Vasp,Csf3,Pdgfb,Pdgfrb,Fzd5,Plek,Jarid2,Il1b,Plaur,Tnfsf10,Spire1,Cdc42ep4,Smc5,Prdm9,Stap1,Prkce,Edn1,Pla2g4a,Bnip3,Cyfip1,Bcl2l11,Cdc42ep2,Sdc4,Mul1,Phip,Sdc1,Kat2b,Evl,Nck1,Rhou,Sirt1,Rictor,Casp8,Cav1,Rnf31,Jdp2,Atm,Stard7,Fam162a,Hcls1,Kdr,Whamm,Fscn1,Adrb2,Lpar1,Mmp9 |
| 1.109e-03 | -6.80 | PUJANA_BRCA1_PCC_NETWORK | MSigDB lists | PUJANA_BRCA1_PCC_NETWORK | 1491 | 151 | 15632 | 1249 |
Pgk1,Ikbke,Il2rg,Mcm6,Parp3,Inhba,Eya4,Il12rb1,Sap30,Asns,Rrs1,Med21,Plek,Cd38,Plagl2,Aim2,Tlk2,Hdac1,Rsad2,Cycs,Ifi209,Tnf,Stat5a,Wdr43,Abcc1,Polr2g,Orai2,Ppp2r1b,Idi1,Adam19,Odc1,Ifi204,Dnajb4,Mthfd2,Mtdh,Max,Pim2,Trim14,Ifi211,Psme2,Rel,Nos2,Mndal,Atm,Ifi207,Atp11b,Prpf4,Me1,Rbl1,Zc3hav1,Slc16a1,Dcp2,Ciapin1,Ifi214,Tpx2,Fas,Nck1,Ap3b1,Ggct,Nat2,Katna1,Gpr18,Ptpn2,Hmga1,Psip1,Syk,Srm,Rnf114,Tcea1,Osbpl3,Snapc1,Dek,Nsmaf,Ptprj,Smc5,Ldha,Wars,Csf3,Hk2,Oas2,Ifi208,Slc7a5,Fubp1,Txn1,Jarid2,Daxx,Relb,Crlf3,Ahsa1,Smg7,Cd180,Itga4,Irf2,Ube2e1,Rhoh,Mdm2,Psma6,Gsr,Tbc1d1,Mdn1,Casp3,Swap70,Cd40,Eno1,Rbbp8,Ifi205,Hsph1,Ifi213,Ifnar1,Ppp6r1,Igf1r,Stard7,Gfi1,Actb,Dr1,Tmem123,Asf1a,Acvr1b,Pik3cd,Gpd2,Casp7,Nox1,Dck,Itpkc,Eef1e1,Hat1,Ifi203,Casp2,Ep400,Trip13,Timeless,Irf8,Psmb8,Ccne1,P4ha1,Prdx1,Ciita,Pfkfb3,Htr2a,Pttg1,Rars,Taf4b,Cox17,Tra2a,Ikzf1,Irf4,Myc,Psmd10,Cenpe,Flt1,Bcl2l11 |
| 1.109e-03 | -6.80 | Rhodanese-like_dom_sf | interpro domains | IPR036873 | 24 | 7 | 19984 | 1430 |
Dusp1,Dusp2,Dusp6,Dusp8,Dusp16,Dusp4,Dusp5 |
| 1.109e-03 | -6.80 | Rhodanese-like_dom | interpro domains | IPR001763 | 24 | 7 | 19984 | 1430 |
Dusp6,Dusp2,Dusp1,Dusp8,Dusp16,Dusp5,Dusp4 |
| 1.112e-03 | -6.80 | antigen receptor-mediated signaling pathway | biological process | GO:0050851 | 119 | 18 | 20694 | 1406 |
Pde4b,Cd38,Rnf31,Cacnb3,Spn,Malt1,Zc3h12a,Icosl,Crkl,Nfkbiz,Syk,Lcp2,Lyn,Ripk2,Themis2,Nfkbid,Bcl2a1d,Dennd1b |
| 1.115e-03 | -6.80 | Il1b (interleukin 1 beta) | protein interactions | 16176 | 6 | 4 | 7778 | 753 |
Tnfaip3,Casp8,Casp1,Ripk3 |
| 1.115e-03 | -6.80 | Nfkbiz (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta) | protein interactions | 80859 | 6 | 4 | 7778 | 753 |
Nfkb1,Nfkb2,Il6,Ikbkg |
| 1.115e-03 | -6.80 | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | 70 | 14 | 15632 | 1249 |
Uchl1,Atf3,Rab20,Slc30a1,Ccnd2,Klf7,Abtb2,Jun,Asns,Plk2,Pla2g4a,Cd69,Cers6,Ccnd1 |
| 1.115e-03 | -6.80 | ROSS_ACUTE_MYELOID_LEUKEMIA_CBF | MSigDB lists | ROSS_ACUTE_MYELOID_LEUKEMIA_CBF | 70 | 14 | 15632 | 1249 |
Atp2b4,Il15ra,Cd34,Ciita,Clec5a,Hif1a,Abr,Ptgir,Isg20,Dusp2,Cav1,Sipa1l1,Junb,Dusp6 |
| 1.115e-03 | -6.80 | TOOKER_GEMCITABINE_RESISTANCE_UP | MSigDB lists | TOOKER_GEMCITABINE_RESISTANCE_UP | 70 | 14 | 15632 | 1249 |
Ciapin1,Acvr1b,Odc1,Isg15,Arid5b,Palld,Tpi1,Sp110,Acsl5,Bambi,Pde4b,Ass1,Sat1,Trim21 |
| 1.115e-03 | -6.80 | GO_FC_GAMMA_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_FC_GAMMA_RECEPTOR_SIGNALING_PATHWAY | 70 | 14 | 15632 | 1249 |
Lyn,Clec4d,Fgr,Cyfip1,Syk,Src,Nck1,Ptk2,Myo10,Hck,Clec4e,Fcgr1,Prkce,Actb |
| 1.116e-03 | -6.80 | extracellular region | cellular component | GO:0005576 | 2389 | 199 | 20747 | 1409 |
Fam20c,Casp4,Hsph1,Ifna1,Ntng2,Smpdl3b,Tsku,Plau,Gdf15,Gbp3,Gbp9,Svbp,Cd14,Spn,Cxcl1,Lrch3,Il1a,Mmp25,Angpt1,Mmp9,Ctsc,Vasn,H2-T22,Cpd,Nlrp3,Raet1e,Lif,Ifna2,Il15,Lgals9,Il10,Ldlr,Csf3,Ifna5,Il27,Flrt3,Dnase1l3,Cnp,Sele,Ccr3,Pdgfc,Cxcl14,Tnfsf14,Lox,Saa3,Ifna4,Usb1,Txn1,Plod3,Ccl12,C1ra,Il18,Lipg,Sema4a,Gsdmd,Il15ra,Crim1,Bmp2,Ifna6,Met,Fas,Thbs1,Nampt,Il6,Gbp8,Arrdc4,Insl6,Plat,Ppfia3,Endod1,Ebi3,C3,Glipr2,Slpi,Col27a1,Fabp3,Fgl2,Cd40,Sema4c,F10,Cxcl2,Tpx2,Axl,Ccl2,Tulp3,Ccl22,Il1b,Tnfsf4,Plaur,Asah2,Ifnb1,Casp1,Lad1,Fcgr2b,C1rl,Pdgfb,Col11a2,H2-T10,Ltbp2,Tnfsf15,H2-M2,Cx3cl1,Vegfc,Serpina3g,Msr1,Aoah,Rnaset2a,Col4a2,Kitl,Icam1,Ccl9,Agrn,Cd274,Hilpda,Il18bp,Sema3c,Milr1,Edn1,Tnfsf9,Plscr1,Serpinb6b,Ccl3,Cxcl3,S100a8,H2-Q6,Tnfsf10,Cd86,H2-T24,Tnfsf8,Iigp1,H2-Q4,Pf4,Cp,Cst7,H2-Q7,Lcn2,Serpinb2,Gbp2,Vcan,Serpinb9,Nos2,Il4ra,Csf1,Serpinb9b,Hp,Vcam1,Osm,Cxcl11,Hsd17b12,Sdc1,Cd34,St3gal1,Col18a1,Srgn,Tnc,Serpine1,Kdr,Irgm2,Timp1,Cxcl10,Ccl4,Adam19,Pnp2,Gbp2b,Ccl5,Ccl8,Isg15,Kmo,Itga4,Sdc4,Rnaset2b,Mmp14,Procr,Serpina3f,Ptch1,Ccl7,Olr1,Tgfbi,Mmp13,Gpc1,Il12b,Flrt2,Pgk1,Il1rn,Gbp7,Lrp8,Cxcl9,Htra1,Ctla2a,H60b,Cd180,Lipe,Acpp,Clcf1,Prrg4,Flt1,Inhba,Tnf,Pla2g7 |
| 1.119e-03 | -6.80 | HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP | MSigDB lists | HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP | 55 | 12 | 15632 | 1249 |
Fgl2,Pou2f2,Rasgrp1,Mmp14,Psmb9,Tcf4,Hspa1a,Aoah,Pf4,Tnfaip3,Cd74,Stat1 |
| 1.119e-03 | -6.80 | chr1q25 | MSigDB lists | chr1q25 | 55 | 12 | 15632 | 1249 |
Tor3a,Rgl1,Trmt1l,Lad1,Cep350,Pla2g4a,Tor1aip2,Stx6,Tnfsf4,Ptgs2,Smg7,Atp2b4 |
| 1.119e-03 | -6.80 | BIOCARTA_PPARA_PATHWAY | MSigDB lists | BIOCARTA_PPARA_PATHWAY | 55 | 12 | 15632 | 1249 |
Ptgs2,Nr1h3,Prkar2b,Me1,Nos2,Cited2,Jun,Stat5a,Tnf,Dusp1,Nfkbia,Myc |
| 1.126e-03 | -6.79 | Ig_C1-set | interpro domains | IPR003597 | 61 | 12 | 19984 | 1430 |
H2-T10,Tapbpl,Tapbp,H2-Eb1,H2-Q7,H2-Q4,H2-Q6,H2-M2,H2-T24,H2-Aa,H2-T22,H2-Ab1 |
| 1.133e-03 | -6.78 | Focal Adhesion | WikiPathways | WP85 | 185 | 35 | 4813 | 540 |
Hck,Pik3r5,Itgav,Itga5,Pdgfb,Ptk2,Map2k1,Vegfc,Thbs1,Ccnd2,Pdgfc,Akt3,Birc2,Met,Pik3cd,Jun,Rac3,Itgb8,Tnc,Actb,Flt1,Cav1,Col4a2,Src,Zyx,Crkl,Ccnd1,Itgal,Fgr,Birc3,Itga4,Col11a2,Itga9,Vasp,Pdgfrb |
| 1.135e-03 | -6.78 | ATPase regulator activity | molecular function | GO:0060590 | 39 | 9 | 20217 | 1400 |
Dnaja1,Dnajb2,Hsph1,Ahsa1,Dnaja2,Dnajb4,Tor1aip1,Tor1aip2,Agrn |
| 1.155e-03 | -6.76 | GO_CYSTEINE_TYPE_PEPTIDASE_ACTIVITY | MSigDB lists | GO_CYSTEINE_TYPE_PEPTIDASE_ACTIVITY | 145 | 23 | 15632 | 1249 |
Casp2,Usp35,Usp12,Casp4,Casp8,Tnip1,Gca,Cflar,Uchl1,Zc3h12a,Casp7,Usp31,Usp42,Ctsc,Casp3,Usp53,Casp1,Otud1,Vcpip1,Tnfaip3,Usp25,Malt1,Usp18 |
| 1.156e-03 | -6.76 | GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN | 199 | 29 | 15632 | 1249 |
Tpi1,Abr,Irak3,Hck,Cd14,Mgat1,Slc16a3,Casp1,Cers6,Rin2,Nod2,Vcan,Sema4a,Tlr2,Mtmr14,Glrx,Gca,Tnfaip2,Notch2,Ubr4,Itgal,Tnfrsf1b,Dusp6,Slc31a2,S100a8,Kctd12,Vasp,Wars,Ext1 |
| 1.158e-03 | -6.76 | HUANG_FOXA2_TARGETS_UP | MSigDB lists | HUANG_FOXA2_TARGETS_UP | 41 | 10 | 15632 | 1249 |
Psat1,Slc7a11,Homer1,Kat2b,Asns,Rbpms,Jag1,Tnfaip3,Maff,Relb |
| 1.158e-03 | -6.76 | GO_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS | MSigDB lists | GO_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS | 41 | 10 | 15632 | 1249 |
Ccl12,Ccl5,Cx3cl1,Cd74,Thbs1,Csf1,Cxcl1,Cmklr1,Il1b,Cxcl2 |
| 1.158e-03 | -6.76 | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_8_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_8_PRODUCTION | 41 | 10 | 15632 | 1249 |
Tlr2,Hspa1a,Serpine1,Ddx58,Ptger4,Tlr9,Tlr3,Tnf,Il1b,Nod2 |
| 1.158e-03 | -6.76 | GO_RESPONSE_TO_COLD | MSigDB lists | GO_RESPONSE_TO_COLD | 41 | 10 | 15632 | 1249 |
Fos,Adrb2,Cxcl10,Casp8,Plac8,Nfkbia,Hspa2,Rnf34,Il6,Lrp11 |
| 1.161e-03 | -6.76 | PML body | cellular component | GO:0016605 | 73 | 13 | 20747 | 1409 |
Daxx,Sirt1,Smc5,Isg20,Top3a,Ikbke,Morc3,Pml,Sp100,N4bp1,Max,Ciita,Sqstm1 |
| 1.162e-03 | -6.76 | GO_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS | 48 | 11 | 15632 | 1249 |
Ripk3,Fas,Hif1a,Cd74,Lyn,Irs2,Nfkbid,Ccl5,Cd274,Il10,Bcl6 |
| 1.162e-03 | -6.76 | GO_NEGATIVE_REGULATION_OF_COAGULATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_COAGULATION | 48 | 11 | 15632 | 1249 |
Serpinb2,Plat,Pdgfb,Cd34,Procr,Edn1,Plau,Plaur,Adrb2,Serpine1,Ubash3b |
| 1.162e-03 | -6.76 | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | 48 | 11 | 15632 | 1249 |
Rabgef1,Spn,H2-Q4,H2-Q6,Bcl6,Ifnb1,Abr,H2-Q7,Hmox1,Serpinb9,Tap1 |
| 1.162e-03 | -6.76 | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN | MSigDB lists | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN | 48 | 11 | 15632 | 1249 |
Gja1,Ccl12,Ifit1bl2,Pde4b,Ifit1bl1,Ptger4,S100a8,Tgfbi,Cd14,Tnfsf10,Plau |
| 1.162e-03 | -6.76 | SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP | MSigDB lists | SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP | 48 | 11 | 15632 | 1249 |
Mthfd2,Ldha,Hck,Prdx1,Bcl2a1a,Eno1,Hmga1,Bcl2a1b,Bcl2a1d,Psme2,Sat1 |
| 1.162e-03 | -6.76 | GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION | MSigDB lists | GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION | 48 | 11 | 15632 | 1249 |
Ptger4,Lpar1,Trib1,Plau,Src,Ccl5,Dock4,Serpine1,P2ry2,Pdgfrb,Pdgfb |
| 1.162e-03 | -6.76 | ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_DN | 48 | 11 | 15632 | 1249 |
Fam162a,Tle3,Zc3hav1,1600014C10Rik,Dmxl2,Rasgrp1,Myc,Tap2,Arhgef3,Tcf4,Ccne1 |
| 1.166e-03 | -6.75 | positive regulation of response to wounding | biological process | GO:1903036 | 73 | 13 | 20694 | 1406 |
Thbs1,Ccl2,Plek,Ptprj,Scarf1,Enpp4,Plpp3,Igf1r,Ptger4,Serpine1,Hopx,Pdpn,Prkce |
| 1.166e-03 | -6.75 | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_UP | MSigDB lists | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_UP | 7 | 4 | 15632 | 1249 |
Bcl2l11,Tnfaip3,Cd40,Trib3 |
| 1.166e-03 | -6.75 | KUWANO_RNA_STABILIZED_BY_NO | MSigDB lists | KUWANO_RNA_STABILIZED_BY_NO | 7 | 4 | 15632 | 1249 |
Gadd45b,Hmox1,Chic2,Ptgs2 |
| 1.166e-03 | -6.75 | ST_IL_13_PATHWAY | MSigDB lists | ST_IL_13_PATHWAY | 7 | 4 | 15632 | 1249 |
Tyk2,Il4ra,Il13ra1,Jak2 |
| 1.166e-03 | -6.75 | FARDIN_HYPOXIA_9 | MSigDB lists | FARDIN_HYPOXIA_9 | 7 | 4 | 15632 | 1249 |
Ddit4,Bnip3,Ak4,Fam162a |
| 1.166e-03 | -6.75 | WANG_ESOPHAGUS_CANCER_PROGRESSION_UP | MSigDB lists | WANG_ESOPHAGUS_CANCER_PROGRESSION_UP | 7 | 4 | 15632 | 1249 |
Dusp2,Myadm,Plaur,Cxcl2 |
| 1.166e-03 | -6.75 | SCHRAMM_INHBA_TARGETS_UP | MSigDB lists | SCHRAMM_INHBA_TARGETS_UP | 7 | 4 | 15632 | 1249 |
Ccnd1,Tgfbi,Dusp4,Lmo4 |
| 1.166e-03 | -6.75 | BUDHU_LIVER_CANCER_METASTASIS_DN | MSigDB lists | BUDHU_LIVER_CANCER_METASTASIS_DN | 7 | 4 | 15632 | 1249 |
Il1a,Il12b,Il1b,Tnf |
| 1.166e-03 | -6.75 | positive regulation of protein polyubiquitination | biological process | GO:1902916 | 13 | 5 | 20694 | 1406 |
Nod2,Birc3,Birc2,Fbxo4,Nmi |
| 1.166e-03 | -6.75 | negative regulation of interleukin-1 secretion | biological process | GO:0050711 | 13 | 5 | 20694 | 1406 |
Zc3h12a,Nlrp3,Tnfaip3,Ptger4,Pml |
| 1.166e-03 | -6.75 | CD4-positive, alpha-beta T cell lineage commitment | biological process | GO:0043373 | 13 | 5 | 20694 | 1406 |
Batf,Stat3,Irf4,Spn,Il6 |
| 1.166e-03 | -6.75 | regulation of protein deubiquitination | biological process | GO:0090085 | 13 | 5 | 20694 | 1406 |
Tnip1,Dnajb2,Tank,Zc3h12a,Trim21 |
| 1.166e-03 | -6.75 | negative regulation of alpha-beta T cell proliferation | biological process | GO:0046642 | 13 | 5 | 20694 | 1406 |
Cd274,Arg2,Tnfrsf14,Lgals9,Tarm1 |
| 1.166e-03 | -6.75 | negative regulation of vasoconstriction | biological process | GO:0045906 | 13 | 5 | 20694 | 1406 |
Dusp5,Hif1a,Dock4,Ahr,Cx3cl1 |
| 1.166e-03 | -6.75 | I-kappaB phosphorylation | biological process | GO:0007252 | 13 | 5 | 20694 | 1406 |
Tlr2,Ikbke,Saa3,Tlr3,Tlr9 |
| 1.166e-03 | -6.75 | positive regulation of metanephros development | biological process | GO:0072216 | 13 | 5 | 20694 | 1406 |
Pdgfb,Lif,Myc,Egr1,Pdgfrb |
| 1.174e-03 | -6.75 | mouse chr4 | chromosome location | mouse chr4 | 436 | 43 | 24173 | 1464 |
Mob3b,Mdn1,Tnfsf8,Gem,Slc2a1,Mthfr,Prdx1,Fabp3,Pou3f1,Csf3r,Lyn,Isg15,Lpar1,Ifna2,Jun,Txn1,Tal2,Eno1,Mycl,Pde4b,Ifna6,Ifnb1,Ptafr,Ripk2,Kdm4a,Slc9a1,Ifna4,Tnfrsf1b,Marcksl1,Ak4,Casz1,Agrn,Inpp5b,Ifna1,Tnfrsf8,Rgs3,Fgr,Hdac1,Plpp3,Ifna5,Tnc,Tgs1,Agtrap |
| 1.175e-03 | -6.75 | GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_DN | MSigDB lists | GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_DN | 154 | 24 | 15632 | 1249 |
Sdc1,F11r,Myd88,Gpr68,Glipr2,S1pr2,Igsf6,Rab21,Sema4a,Fpr1,Slamf8,Il13ra1,Glrx,Sec24a,Gca,Gfpt1,Osbpl3,Psmb8,Snx10,Stx11,Stat4,Wars,Slpi,Fabp7 |
| 1.177e-03 | -6.74 | regulation of proteasomal protein catabolic process | biological process | GO:0061136 | 180 | 24 | 20694 | 1406 |
Usp25,Psme2,Hspa1a,Plk3,Rnf14,Ankib1,Plk2,N4bp1,Rnf19a,Hspa1b,Tlk2,Caml,Sco1,Tmem67,Trib1,Dnajb2,Nupr1,Psmd10,Mdm2,Psme1,Rnf19b,Cop1,Trib3,Gclc |
| 1.183e-03 | -6.74 | GSE34515_CD16_NEG_MONOCYTE_VS_DC_DN | MSigDB lists | GSE34515_CD16_NEG_MONOCYTE_VS_DC_DN | 181 | 27 | 15632 | 1249 |
Cnot4,Parp9,Cers6,Enpp4,Psme1,Stxbp1,Cdkn2d,Wars,Il12rb1,Pou2f2,Rilpl1,Ube2l6,Slc7a5,Marco,Lap3,Casp8,Gja1,Sesn3,Brd2,5430427O19Rik,Elmod2,Znrf1,Clic4,Acvr1b,Ifi35,Usp31,Max |
| 1.183e-03 | -6.74 | GSE29618_MONOCYTE_VS_MDC_DN | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_DN | 181 | 27 | 15632 | 1249 |
Ccnd2,Pttg1,Klf8,Tab2,Evl,Zc3hav1,Samhd1,Ciita,Hmga1,Slc2a1,Axl,Cnn2,Ppp1r14b,Cst7,Irf4,Dennd1b,Mob3b,Il2rg,Il18,H2-Ab1,Il13ra1,Ppa1,Fam162a,Wdr43,Rgs1,Sh3bp4,Spint2 |
| 1.183e-03 | -6.74 | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY6_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY6_EFFECTOR_CD8_TCELL_DN | 181 | 27 | 15632 | 1249 |
Cox18,4930453N24Rik,Ifi35,Larp1,Usp31,Stip1,Idi1,Cflar,Tor3a,Nrp2,Traf1,Coa5,Lrp8,Relb,Mvp,Adar,Ube2f,Oas3,Mrpl52,Swap70,Txnrd1,Gadd45b,Nfkbia,Ifrd1,Ubtd2,Cish,Gclm |
| 1.183e-03 | -6.74 | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_UP | MSigDB lists | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_UP | 181 | 27 | 15632 | 1249 |
Nampt,Fzd5,Fosb,Rnf19a,Maff,Pde7b,Itga5,Clec5a,Lox,Il1rn,Cacna1d,Sec24a,Plaur,Tfec,Wdr43,Slc7a11,Sqstm1,P2ry12,Fos,Tpst1,Gpr84,Micall2,Rab9,Gadd45g,Psme1,Gbp3,Cx3cl1 |
| 1.183e-03 | -6.74 | GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_UP | 181 | 27 | 15632 | 1249 |
Traf1,Plagl2,Sdc4,Eno1,Ets2,Bcl2l11,Ezr,Dusp1,Cpd,Nr3c1,Irf4,Serpinb9,Rab20,Slc25a22,Slc43a3,Ldha,Kdm6b,Rcl1,Clic4,Osbpl3,Rrs1,Tnfsf14,Myo1b,Samsn1,Irf8,Ccnj,Csf1 |
| 1.183e-03 | -6.74 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_UP | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_UP | 181 | 27 | 15632 | 1249 |
Tnfrsf14,Slc28a2,Plagl1,Tlr6,Lztfl1,Cebpd,Sat1,Tiparp,Dock4,Plod3,Glrx,Gsta3,Thbs1,Pim1,Itga9,Phyh,Scyl2,Ccrl2,Pla2g7,Wdr59,Tifa,Igsf8,P2ry2,Dach1,Slc4a7,Dusp6,Gch1 |
| 1.183e-03 | -6.74 | GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_UP | 181 | 27 | 15632 | 1249 |
Ak4,Pik3cd,Bcl2a1a,Sec24a,Kitl,Gng12,Snn,Abcc1,Nfil3,Clic5,Casp4,Spen,Herc3,Bmp2,Cdc42ep2,Plagl2,Rab32,Klf6,Cst7,Bcl2a1b,Gpr18,Msr1,Cd40,Tbc1d1,Katna1,S1pr2,Bcl2a1d |
| 1.183e-03 | -6.74 | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN | MSigDB lists | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN | 181 | 27 | 15632 | 1249 |
Ifit1bl2,Irf7,Cav1,Klf2,Kctd12,Rictor,Cx3cr1,Ifit1bl1,Hivep2,Klf3,Cited2,Msr1,Fos,Tet2,Prkce,Abcb1a,D1Ertd622e,Fcgr2b,Rsad2,B3gnt5,Pde5a,Cd200r4,Itga4,Mxd1,Ifih1,Aldh1b1,Pttg1 |
| 1.184e-03 | -6.74 | tube closure | biological process | GO:0060606 | 110 | 17 | 20694 | 1406 |
Lhx2,Sec24b,Ift57,Apaf1,Mthfd1l,Sdc4,Phactr4,Tulp3,Cited2,Casp3,Mthfr,Lmo4,Ptch1,Sema4c,Spint2,Vasp,Fzd1 |
| 1.186e-03 | -6.74 | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | MSigDB lists | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | 163 | 25 | 15632 | 1249 |
Slc39a4,Ccnd1,Dusp4,Ehd1,Rab32,Mgat1,Trip10,Tsku,Olfml3,Ier2,Asap3,Sdc1,Arl4a,Ext1,Ccdc25,Slc39a14,Kctd12,Rgl1,Plk2,Igf2bp2,Ptger4,Dennd2a,Slc43a3,Lpar1,Cdc42ep4 |
| 1.186e-03 | -6.74 | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP | 163 | 25 | 15632 | 1249 |
Xkr8,Irf2,Zc3h12a,Phf11d,Atp11a,Ifih1,Il1rn,Cacna1d,Crlf3,Phf11a,Prkx,Phf11c,Pde4b,Phf11b,Ppp6r1,Ifnar1,Tnfsf14,Casz1,Sik3,Trim14,Pdgfb,Slc44a1,Uba7,Syne2,Dgka |
| 1.186e-03 | -6.74 | DARWICHE_SKIN_TUMOR_PROMOTER_DN | MSigDB lists | DARWICHE_SKIN_TUMOR_PROMOTER_DN | 163 | 25 | 15632 | 1249 |
Cx3cr1,Bcl2a1b,Itpr1,Otud1,Swap70,Mgat1,Gclm,Cp,Chst11,Bcl2a1d,Slc39a13,Fbrsl1,Cdc42ep2,Samhd1,Txn1,Cacybp,Asns,Scn1b,Rnf19a,Jag1,Denr,Bcl2a1a,Fam162a,Il1b,Pmepa1 |
| 1.186e-03 | -6.74 | GO_DENDRITIC_CELL_DIFFERENTIATION | MSigDB lists | GO_DENDRITIC_CELL_DIFFERENTIATION | 28 | 8 | 15632 | 1249 |
Cd86,Azi2,Lyn,Axl,Relb,Irf4,Batf,Batf2 |
| 1.186e-03 | -6.74 | GNF2_MMP1 | MSigDB lists | GNF2_MMP1 | 28 | 8 | 15632 | 1249 |
Plod2,Serpine1,Ccl12,Csf3,Il1b,Cxcl2,Il6,Rai14 |
| 1.186e-03 | -6.74 | GO_POSITIVE_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE | 28 | 8 | 15632 | 1249 |
Tnf,C3,Ccl5,Ptgs2,Osm,Pla2g4a,Il6,Il1b |
| 1.187e-03 | -6.74 | cell projection | cellular component | GO:0042995 | 2419 | 201 | 20747 | 1409 |
Ddx58,Pdlim7,Itga5,Htr2a,Nqo1,Cnn3,Sqstm1,Ldha,Rhoc,Psd,Clic5,Cd200,Tmem67,Stxbp1,Cpeb4,Glrx,Ksr1,Casp8,Actb,Rpgrip1l,Slc7a11,Abcc4,Uchl1,Ezr,Hif1a,Prnp,Vezt,Scimp,Ass1,Rab10,Palld,Plk2,Adora2a,Agrn,Hk1,Kitl,Cav1,Cx3cl1,Irgm1,Rab21,Fzd1,Dock4,Kif3c,Abcb1a,Triobp,Katna1,Acpp,Ctla2a,Adrb2,Lrp8,Vasp,Evl,Igsf9,Rilpl1,Sipa1l1,Rhoq,Psd4,Rgs14,Stat1,Hck,Flrt2,Fscn1,Lrp4,Rapgef2,Apba1,Bst1,Ptch1,Eif4g2,Daxx,Itga4,Phlpp1,Cyfip1,Nfkb1,Htr2b,Ptk2,Fgr,P2ry12,Cacna1d,Tlr2,Kdr,Sphk1,Nrp2,Carmil1,Dbnl,Rac3,Max,Dock10,Acp2,Ehd1,Fchsd2,Fzd5,Notch2,Micall2,Ptger4,Ptgs2,Vcam1,Cacybp,Antxr1,Trip10,Kcnj2,Ero1l,Rhou,Fos,Grk3,Swap70,Cdk5r1,Spry2,Cnp,Cx3cr1,Flrt3,Kcna3,Clic4,Tmod3,Cyth3,Ptprj,Syne2,Sirt1,Bnip3,Pde4b,Orai2,Arf4,Angpt1,Phactr4,Xrn1,Mark2,Src,Dync1h1,Spn,Mtmr14,Nox1,Hdc,Prkar2b,Myo1b,Mefv,Eno2,Tnfrsf1b,Samsn1,Eno1,Igf1r,Atp2b4,Ntng2,Daam1,Myadm,Casp4,Igsf8,Dmwd,Pdgfb,Casp1,Slc39a14,Nr3c1,Myo10,Map2k1,Fcgr2b,Asap3,Mul1,Map2k4,Stau1,Lpar1,Tulp3,Itgav,Cd302,Ift22,Ccl2,Tpx2,Optn,Adgrl2,Cd40,Kif5c,Homer1,Hdac1,Spata13,Plek,D1Ertd622e,Snx2,Flnb,Scn1b,Dst,Plk3,Rab3ip,Hap1,Cenpj,Cep350,Ift57,Fas,Met,Piezo1,Nlgn2,Slc4a7,Rap1gap2,Pdpn,Itpr1,Mosmo,Phlpp2,Myc,Acvrl1,Fabp7,Rhoh,Atp6v1d,Intu,Osbpl3,Txn1 |
| 1.187e-03 | -6.74 | transcription factor AP-1 complex | cellular component | GO:0035976 | 4 | 3 | 20747 | 1409 |
Junb,Jun,Fos |
| 1.187e-03 | -6.74 | CD95 death-inducing signaling complex | cellular component | GO:0031265 | 4 | 3 | 20747 | 1409 |
Fas,Cflar,Casp8 |
| 1.188e-03 | -6.74 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | 172 | 26 | 15632 | 1249 |
Map3k6,Ythdf1,Ccnd1,Socs1,Il1a,Mcm10,Dusp14,Etv5,Pnpt1,Batf,Klf2,Tnfsf14,Tnfrsf1b,Eef1e1,Wars,Alas1,Pdss1,Spen,Rilpl1,Serpinb9,Mafg,Trib1,Adora2b,Ldha,Egr3,Pkp4 |
| 1.188e-03 | -6.74 | CHANDRAN_METASTASIS_UP | MSigDB lists | CHANDRAN_METASTASIS_UP | 172 | 26 | 15632 | 1249 |
P4ha1,S100a8,Ogfr,Slc7a5,Ep400,Ddit4,Wdfy1,Ripk2,Larp1,Cpeb4,Map3k8,Lyn,Ak4,Fscn1,Stard7,Dync1h1,Itpr1,Dusp8,Vcan,Cdkn2d,Nupr1,Magohb,Lrch3,Tpx2,Zfp281,Slc16a1 |
| 1.188e-03 | -6.74 | GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_DN | MSigDB lists | GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_DN | 172 | 26 | 15632 | 1249 |
Cers6,Psd,Rnf24,Ppp2r5a,Cd302,Gpr18,Clmp,Hivep2,Klf7,Rab3ip,Bcor,Trim56,Rapgef2,Btg2,Col11a2,Card6,Sesn3,Map4k4,Pde4b,Snn,Rcl1,Znrf1,Mppe1,Dyrk2,Filip1l,Egr3 |
| 1.188e-03 | -6.74 | GSE19374_UNINF_VS_LISTERIA_INFECTED_MACROPHAGE_DN | MSigDB lists | GSE19374_UNINF_VS_LISTERIA_INFECTED_MACROPHAGE_DN | 172 | 26 | 15632 | 1249 |
Tab2,Sertad3,Gys1,Lipe,Slc16a3,Dock4,D16Ertd472e,Abcb1a,Lrch1,Arhgap26,Rbpms,Fam53c,Zc3h12a,Tmod3,Trib1,Gtpbp2,Vrk2,Glrx,Nampt,Lnpep,Samsn1,Adap2,Slc9a1,Noc4l,Sh3bp4,Maff |
| 1.188e-03 | -6.74 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_UP | 172 | 26 | 15632 | 1249 |
Ust,Slfn3,Cxcl1,Cflar,Tlr2,Mthfd2,Eya4,Inhba,Wars,Casp4,Asns,Plk2,Slfn4,Ccl5,Prpf38a,Clcn5,Pim3,Nlrp3,Il1a,Apba1,Rars,Ccnd1,Tbc1d1,Phgdh,Sbds,Fam43a |
| 1.188e-03 | -6.74 | lamellipodium membrane | cellular component | GO:0031258 | 8 | 4 | 20747 | 1409 |
Itgav,Antxr1,Pdpn,Syne2 |
| 1.188e-03 | -6.74 | cellular response to mycotoxin | biological process | GO:0036146 | 4 | 3 | 20694 | 1406 |
Pdgfb,Egr1,Actb |
| 1.188e-03 | -6.74 | positive regulation of natural killer cell chemotaxis | biological process | GO:2000503 | 4 | 3 | 20694 | 1406 |
Ccl5,Ccl4,Cxcl14 |
| 1.188e-03 | -6.74 | regulation of mast cell cytokine production | biological process | GO:0032763 | 4 | 3 | 20694 | 1406 |
Nr4a3,Hmox1,Bcl6 |
| 1.188e-03 | -6.74 | helper T cell extravasation | biological process | GO:0035684 | 4 | 3 | 20694 | 1406 |
Ccl5,Ccl2,Crkl |
| 1.188e-03 | -6.74 | detection of bacterial lipoprotein | biological process | GO:0042494 | 4 | 3 | 20694 | 1406 |
Tlr1,Tlr2,Tlr6 |
| 1.188e-03 | -6.74 | response to diacyl bacterial lipopeptide | biological process | GO:0071724 | 4 | 3 | 20694 | 1406 |
Tlr6,Tlr2,Cd14 |
| 1.188e-03 | -6.74 | regulation of MyD88-dependent toll-like receptor signaling pathway | biological process | GO:0034124 | 4 | 3 | 20694 | 1406 |
Cd300lf,Irf7,Irf1 |
| 1.188e-03 | -6.74 | positive regulation of ovulation | biological process | GO:0060279 | 4 | 3 | 20694 | 1406 |
Plau,Inhba,Plat |
| 1.188e-03 | -6.74 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological process | GO:0002291 | 4 | 3 | 20694 | 1406 |
Itgal,Icam1,Fgl2 |
| 1.188e-03 | -6.74 | cellular response to diacyl bacterial lipopeptide | biological process | GO:0071726 | 4 | 3 | 20694 | 1406 |
Cd14,Tlr2,Tlr6 |
| 1.188e-03 | -6.74 | positive regulation of mast cell proliferation | biological process | GO:0070668 | 4 | 3 | 20694 | 1406 |
Stat5a,Kitl,Lyn |
| 1.188e-03 | -6.74 | cellular response to cisplatin | biological process | GO:0072719 | 4 | 3 | 20694 | 1406 |
Timeless,Slc31a1,Hmox1 |
| 1.190e-03 | -6.73 | regulation of interleukin-18 production | biological process | GO:0032661 | 8 | 4 | 20694 | 1406 |
Nod2,Tlr9,Tnf,Tlr2 |
| 1.190e-03 | -6.73 | positive regulation of RIG-I signaling pathway | biological process | GO:1900246 | 8 | 4 | 20694 | 1406 |
Dhx58,Ddx60,Ankrd17,Zc3hav1 |
| 1.190e-03 | -6.73 | regulation of platelet-derived growth factor receptor-beta signaling pathway | biological process | GO:2000586 | 8 | 4 | 20694 | 1406 |
Lox,Src,Glrx,Ptpn2 |
| 1.190e-03 | -6.73 | T-helper 17 cell lineage commitment | biological process | GO:0072540 | 8 | 4 | 20694 | 1406 |
Batf,Stat3,Irf4,Il6 |
| 1.190e-03 | -6.73 | regulation of long-chain fatty acid import into cell | biological process | GO:0140212 | 8 | 4 | 20694 | 1406 |
Fabp3,Thbs1,Irs2,Acsl5 |
| 1.190e-03 | -6.73 | inflammatory response to wounding | biological process | GO:0090594 | 8 | 4 | 20694 | 1406 |
Hmox1,Il1a,Hif1a,Timp1 |
| 1.190e-03 | -6.73 | negative regulation of CD4-positive, alpha-beta T cell proliferation | biological process | GO:2000562 | 8 | 4 | 20694 | 1406 |
Lgals9,Tarm1,Cd274,Arg2 |
| 1.190e-03 | -6.73 | positive regulation of natural killer cell mediated immune response to tumor cell | biological process | GO:0002857 | 8 | 4 | 20694 | 1406 |
Klrk1,Pvr,Nectin2,Il12b |
| 1.190e-03 | -6.73 | wound healing involved in inflammatory response | biological process | GO:0002246 | 8 | 4 | 20694 | 1406 |
Timp1,Hif1a,Hmox1,Il1a |
| 1.190e-03 | -6.73 | negative regulation of hydrogen peroxide-mediated programmed cell death | biological process | GO:1901299 | 8 | 4 | 20694 | 1406 |
Glrx,Met,Hk3,Hsph1 |
| 1.192e-03 | -6.73 | C1-set | pfam domains | PF07654 | 61 | 12 | 18711 | 1348 |
H2-Q6,Tapbpl,H2-Eb1,H2-T24,Tapbp,H2-T22,H2-M2,H2-Aa,H2-Q4,H2-T10,H2-Q7,H2-Ab1 |
| 1.194e-03 | -6.73 | ATPase activator activity | molecular function | GO:0001671 | 25 | 7 | 20217 | 1400 |
Dnajb2,Dnaja1,Ahsa1,Dnajb4,Tor1aip1,Dnaja2,Tor1aip2 |
| 1.194e-03 | -6.73 | regulation of DNA-templated transcription in response to stress | biological process | GO:0043620 | 56 | 11 | 20694 | 1406 |
Nck1,Klf2,Cited2,Ppp1r15a,Hif1a,Atf3,Jun,Rgs14,Egr1,Notch1,Hmox1 |
| 1.194e-03 | -6.73 | regulation of antigen receptor-mediated signaling pathway | biological process | GO:0050854 | 56 | 11 | 20694 | 1406 |
Ezr,Ptprj,Nectin2,Fcgr2b,Plcl2,Malt1,Ptpn2,Prnp,Lyn,Usp12,Stap1 |
| 1.194e-03 | -6.73 | positive regulation of wound healing | biological process | GO:0090303 | 56 | 11 | 20694 | 1406 |
Serpine1,Prkce,Enpp4,Hopx,Ptprj,Pdpn,Ptger4,Thbs1,Plpp3,Ccl2,Plek |
| 1.195e-03 | -6.73 | BIOCARTA_IL6_PATHWAY | MSigDB lists | BIOCARTA_IL6_PATHWAY | 22 | 7 | 15632 | 1249 |
Il6,Stat3,Jak2,Tyk2,Map2k1,Jun,Fos |
| 1.195e-03 | -6.73 | BIOCARTA_CHEMICAL_PATHWAY | MSigDB lists | BIOCARTA_CHEMICAL_PATHWAY | 22 | 7 | 15632 | 1249 |
Cycs,Casp3,Apaf1,Casp7,Atm,Ptk2,Stat1 |
| 1.195e-03 | -6.73 | BIOCARTA_CERAMIDE_PATHWAY | MSigDB lists | BIOCARTA_CERAMIDE_PATHWAY | 22 | 7 | 15632 | 1249 |
Casp8,Nsmaf,Map2k1,Map2k4,Traf2,Nfkb1,Cycs |
| 1.195e-03 | -6.73 | GO_REGULATION_OF_INTERLEUKIN_17_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_17_PRODUCTION | 22 | 7 | 15632 | 1249 |
Myd88,Il15,Nod2,Tnfsf4,Prnp,Il18,Il12b |
| 1.195e-03 | -6.73 | GO_G_PROTEIN_ALPHA_SUBUNIT_BINDING | MSigDB lists | GO_G_PROTEIN_ALPHA_SUBUNIT_BINDING | 22 | 7 | 15632 | 1249 |
Rgs14,Lpar1,Gpsm2,Adrb2,Rgs1,Htr2a,Htr2b |
| 1.199e-03 | -6.73 | regulation of actin filament organization | biological process | GO:0110053 | 255 | 31 | 20694 | 1406 |
Evl,Nck1,Csf3,Plek,Cdc42ep4,Met,Cdc42ep2,Whamm,Sdc4,Hcls1,Ptger4,Cyfip1,Vasp,Lpar1,Fchsd2,Tmod3,Cx3cl1,Swap70,Rhoc,Rac3,Dbnl,Asap3,Rictor,Tmsb10,Carmil1,Rgcc,Icam1,Spire1,Tlr2,Prkce,Myadm |
| 1.200e-03 | -6.73 | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | MSigDB lists | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | 218 | 31 | 15632 | 1249 |
Slc29a3,Ifi204,Endod1,Kdm6b,Ifi203,Tbc1d13,Eya4,Ifi208,Plscr1,Ifi211,Isg20,Mndal,Daam1,Dach1,Rgs3,Ifi207,Pde3b,Tspo,Jmjd6,Ifi214,Plagl1,Optn,Cp,Sat1,Irgq,Ifi205,Ifi209,Rgs14,Lrp4,Flt1,Ifi213 |
| 1.203e-03 | -6.72 | regulation of extracellular matrix organization | biological process | GO:1903053 | 40 | 9 | 20694 | 1406 |
Tnfrsf1b,Antxr1,Il6,Fscn1,Rgcc,Notch1,Pdpn,Cflar,Phldb1 |
| 1.203e-03 | -6.72 | regulation of astrocyte differentiation | biological process | GO:0048710 | 40 | 9 | 20694 | 1406 |
Mecp2,Lif,Kdm4a,Il1b,Bmp2,Ldlr,Clcf1,Hmga2,Notch1 |
| 1.207e-03 | -6.72 | TNF | pfam domains | PF00229 | 18 | 6 | 18711 | 1348 |
Tnfsf9,Tnfsf8,Tnfsf15,Tnfsf14,Tnfsf10,Tnf |
| 1.217e-03 | -6.71 | peptidase activator activity | molecular function | GO:0016504 | 32 | 8 | 20217 | 1400 |
Psme2,Cflar,Tank,Apaf1,Mmp25,Ctsc,Psme1,Cav1 |
| 1.217e-03 | -6.71 | NF-kappaB binding | molecular function | GO:0051059 | 32 | 8 | 20217 | 1400 |
Nfkbid,Psma6,Taf4b,Notch2,Hdac1,Nfkbia,Mtdh,Hspa1a |
| 1.223e-03 | -6.71 | growth factor binding | molecular function | GO:0019838 | 147 | 21 | 20217 | 1400 |
Thbs1,Gpc1,Kdr,Htra1,Dusp1,Acvr1b,Vasn,Acvrl1,Itgav,Ltbp2,Pdgfb,Flt1,Crim1,Il1rn,Hap1,Il2rg,Agrn,Igf1r,Acvr1,Csf3r,Pdgfrb |
| 1.223e-03 | -6.71 | positive regulation of purine nucleotide biosynthetic process | biological process | GO:1900373 | 19 | 6 | 20694 | 1406 |
Stat3,Myc,Map2k1,Nos2,Pid1,Adora2b |
| 1.223e-03 | -6.71 | interleukin-1 production | biological process | GO:0032612 | 19 | 6 | 20694 | 1406 |
Casp1,Nlrp3,Nlrc4,Tlr6,Il1b,Aim2 |
| 1.223e-03 | -6.71 | negative regulation of B cell proliferation | biological process | GO:0030889 | 19 | 6 | 20694 | 1406 |
Prdm1,Il10,Lyn,Atm,Fcgr2b,Casp3 |
| 1.223e-03 | -6.71 | regulation of glial cell migration | biological process | GO:1903975 | 19 | 6 | 20694 | 1406 |
P2ry12,Crkl,Fubp1,Csf1,Stap1,Fas |
| 1.223e-03 | -6.71 | positive regulation of nucleotide biosynthetic process | biological process | GO:0030810 | 19 | 6 | 20694 | 1406 |
Stat3,Myc,Nos2,Map2k1,Adora2b,Pid1 |
| 1.225e-03 | -6.70 | WARTERS_RESPONSE_TO_IR_SKIN | MSigDB lists | WARTERS_RESPONSE_TO_IR_SKIN | 63 | 13 | 15632 | 1249 |
Micall2,Btg2,Mdm2,Gdf15,Plcl2,Notch1,Ppfibp1,Cdkn1a,Dram1,Fas,Dnajb4,Tgfbi,Frmd4a |
| 1.225e-03 | -6.70 | GO_POSITIVE_REGULATION_OF_LIPASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_LIPASE_ACTIVITY | 63 | 13 | 15632 | 1249 |
Htr2a,Arf4,Htr2b,Rhoc,Ptafr,Nr1h3,Lpar1,Prkce,Sele,Ccl5,Flt1,Pdgfrb,Gna15 |
| 1.226e-03 | -6.70 | Tnfrsf1a (tumor necrosis factor receptor superfamily, member 1a) | protein interactions | 21937 | 14 | 6 | 7778 | 753 |
Tnf,Tnip1,Ikbkg,Syk,Rnf31,Tnfaip3 |
| 1.231e-03 | -6.70 | positive regulation of organic acid transport | biological process | GO:0032892 | 48 | 10 | 20694 | 1406 |
Kmo,Il1b,P2ry2,Il1a,Adora2a,Fabp3,Acsl5,Stxbp1,Edn1,Nr3c1 |
| 1.231e-03 | -6.70 | protein destabilization | biological process | GO:0031648 | 48 | 10 | 20694 | 1406 |
Trim21,Prnp,Rnf139,Src,Sirt1,Fbxo4,Mdm2,Bmp2,Mul1,Irgm2 |
| 1.231e-03 | -6.70 | platelet activation | biological process | GO:0030168 | 48 | 10 | 20694 | 1406 |
Ubash3b,Evl,Pf4,Stxbp3,Stxbp1,Plek,P2ry12,Slc7a11,Axl,Cx3cl1 |
| 1.231e-03 | -6.70 | negative regulation of myeloid leukocyte differentiation | biological process | GO:0002762 | 48 | 10 | 20694 | 1406 |
Gpr68,Myc,Tmem178,Ubash3b,Pilrb1,Ptpn2,Lyn,Trib1,Ifnb1,Clec2d |
| 1.248e-03 | -6.69 | positive regulation of animal organ morphogenesis | biological process | GO:0110110 | 101 | 16 | 20694 | 1406 |
Cd34,Sema3c,Myc,Hmga2,Notch1,Bmp2,Acvr1,Pml,Itpr1,Edn1,Lif,Jag1,Csf1,Pim1,Cflar,Tnfaip3 |
| 1.251e-03 | -6.68 | regulation of mitochondrion organization | biological process | GO:0010821 | 130 | 19 | 20694 | 1406 |
Psmd10,Fas,Mul1,Tspo,Fam162a,Hif1a,Kdr,Higd1a,Hk2,Plaur,Stat2,Pmaip1,Ddhd1,Mmp9,Tnfsf10,Bcl2l11,Ier3,Bnip3,Optn |
| 1.253e-03 | -6.68 | Znf_RING/FYVE/PHD | interpro domains | IPR013083 | 438 | 49 | 19984 | 1430 |
Rnf14,Phf11d,Phf11c,Phf6,Znrf1,Rnf139,Cnot4,Mllt6,Phf11a,Cop1,Kdm5b,Trim21,Rnf114,Rnf31,Trim13,Bfar,Trafd1,Mid1,Nsd3,Trim34a,Znrf3,Pikfyve,Rnf19a,Trim26,Rnf145,Ankib1,Phf11b,Pml,Trim30d,Rnf34,Rnf135,Plekhf2,Mdm2,Rnf19b,Mul1,Trim56,Trim12a,Trim30a,Dtx3l,Pcgf5,Trim12c,Kdm4a,Rffl,Wdfy1,Birc3,Dtx2,Traf2,Traf5,Rnf24 |
| 1.254e-03 | -6.68 | PID_ERBB1_DOWNSTREAM_PATHWAY | MSigDB lists | PID_ERBB1_DOWNSTREAM_PATHWAY | 103 | 18 | 15632 | 1249 |
Pik3cd,Map2k4,Stat1,Egr1,Ppp2r2a,Ralgds,Arf4,Jun,Map2k1,Fos,Dusp6,Dusp1,Src,Rictor,Zfp36,Stat3,Ksr1,Slc9a1 |
| 1.254e-03 | -6.68 | KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 103 | 18 | 15632 | 1249 |
Nfkbie,Rasgrp1,Akt3,Nfkbib,Lcp2,Il10,Fos,Jun,Map2k1,Nfkbia,Tnf,Nfkb1,Ikbkg,Pik3r5,Pik3cd,Map3k8,Malt1,Nck1 |
| 1.257e-03 | -6.68 | peptidyl-lysine 5-dioxygenase activity | molecular function | GO:0070815 | 4 | 3 | 20217 | 1400 |
Plod3,Jmjd6,Plod2 |
| 1.257e-03 | -6.68 | IgG receptor activity | molecular function | GO:0019770 | 4 | 3 | 20217 | 1400 |
Fcgr1,Fcgr4,Fcgr2b |
| 1.257e-03 | -6.68 | activin receptor activity, type I | molecular function | GO:0016361 | 4 | 3 | 20217 | 1400 |
Acvrl1,Acvr1,Acvr1b |
| 1.257e-03 | -6.68 | CCR2 chemokine receptor binding | molecular function | GO:0031727 | 4 | 3 | 20217 | 1400 |
Ccl7,Ccl2,Ccl12 |
| 1.257e-03 | -6.68 | cysteine-type endopeptidase activity involved in execution phase of apoptosis | molecular function | GO:0097200 | 4 | 3 | 20217 | 1400 |
Casp2,Casp7,Casp3 |
| 1.260e-03 | -6.68 | GO_EPITHELIAL_CELL_DIFFERENTIATION | MSigDB lists | GO_EPITHELIAL_CELL_DIFFERENTIATION | 434 | 53 | 15632 | 1249 |
Frmd6,Cdkn1a,Rap2c,Fam20c,Met,Tdrd7,Jag1,Flnb,Cnn3,Ptch1,Ednrb,Clic5,Cd34,Sdc1,Col18a1,Palld,Jun,Dhrs9,Tagln,Slc7a11,Ezr,Pgk1,Sec24b,Clic4,Fndc3a,Kdm6b,Fzd1,Rapgef2,Rab10,Rilpl1,Pdgfb,Map2k1,Klf2,Gja1,Myadm,Slc4a7,Arid4a,Notch1,Bmp2,Sav1,Intu,F11r,Hif1a,Icam1,Prdm1,Hhex,Acvrl1,Hdac1,Acvr1,Kdm5b,Casp3,Gpsm2,Plod3 |
| 1.262e-03 | -6.67 | BENPORATH_OCT4_TARGETS | MSigDB lists | BENPORATH_OCT4_TARGETS | 266 | 36 | 15632 | 1249 |
Hhex,Ifi214,Klf7,Spred1,Ifi207,Olfml3,Prpf38a,Tle3,Ifi213,Ifi205,Ptpn2,Ifi209,Tcf4,Tnc,Phgdh,Stat3,Slc44a1,Rnf24,Tra2a,Gadd45g,Ifi204,Bambi,Kdr,Ppp2r1b,Zhx2,Jarid2,Cdyl,Abtb2,Dusp6,Gja1,Atp6v1d,Mndal,Ifi211,Ifi208,Ppp2r3a,Ifi203 |
| 1.270e-03 | -6.67 | HUANG_GATA2_TARGETS_UP | MSigDB lists | HUANG_GATA2_TARGETS_UP | 146 | 23 | 15632 | 1249 |
Psmb8,Sipa1l1,Tap2,Samsn1,Slc2a6,Kctd12,Hp,Clec4d,Gcnt2,Cdkn1a,Sqstm1,Plac8,Psmb9,Fut8,Sat1,Fcgr2b,Prdx5,Hhex,P2ry14,Clec4e,Tspo,Irak3,Aff1 |
| 1.270e-03 | -6.67 | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP | 146 | 23 | 15632 | 1249 |
Irs2,Cdk5r1,Upp1,Kcna3,Mxd1,Tnfaip3,Clec4e,Whamm,Cited2,Fos,Klf2,Map4k4,Pik3r5,Pde4b,Junb,Parp8,Dusp1,Klf3,Maff,Rap1gap2,Lztfl1,Tnfsf8,Btg2 |
| 1.271e-03 | -6.67 | GSE30083_SP2_VS_SP3_THYMOCYTE_DN | MSigDB lists | GSE30083_SP2_VS_SP3_THYMOCYTE_DN | 191 | 28 | 15632 | 1249 |
Uaca,Dck,Oas1g,Clcf1,Tnfaip2,Col27a1,Clic4,Igsf8,Lmo4,Ifit1bl2,Oas1a,Csf3,Pstpip2,Tlr1,Sell,Rnf135,Itga4,Hhex,Mcoln2,Rnf34,Rras2,Klf3,Ifit1bl1,Abcc5,Pde5a,B3gnt5,C1ra,Ppp2r5a |
| 1.273e-03 | -6.67 | Toll-like receptor signaling | KEGG pathways | mmu_M00686 | 15 | 6 | 7931 | 713 |
Nfkb1,Tlr2,Tab2,Myd88,Nfkbia,Ikbkg |
| 1.273e-03 | -6.67 | Toll-like receptor signaling | KEGG pathways | M00686 | 15 | 6 | 7931 | 713 |
Nfkb1,Ikbkg,Myd88,Nfkbia,Tab2,Tlr2 |
| 1.279e-03 | -6.66 | peptidyl-amino acid modification | biological process | GO:0018193 | 801 | 77 | 20694 | 1406 |
Map2k1,Tlk2,Pdk3,Tpst1,Dyrk2,Src,Hck,Cdyl,Prdm9,Plk2,Lox,Mgat1,Nos2,Dpy19l1,Ikbke,Mul1,Acvr1b,Flt1,Pdgfb,Nek6,Lif,Atm,P4ha2,Sla,Ranbp2,Mapkapk2,Tet2,Axl,Akt3,Sirt1,Mdm2,Prkce,Cdk5r1,Tyk2,Osm,Rictor,Il12rb1,Lyn,Jak2,Hat1,Map2k4,Acvr1,S100a8,Met,Eif2ak2,Naa25,Egln3,Stat5a,Arid4a,Egr2,Kdr,Setdb2,Syk,Mecp2,Prkx,Mark2,Sgk3,Ptk2,Plod2,Morc3,P4ha1,Ep400,Irf4,Pdgfrb,Plod3,Il15,Hk1,Nsd3,Jmjd6,Kat2b,Dr1,Ifih1,Igf1r,Fut8,Kmt5a,Vrk2,Fgr |
| 1.283e-03 | -6.66 | EBV LMP1 signaling | WikiPathways | WP1243 | 21 | 8 | 4813 | 540 |
Ccl5,Ifnb1,Nfkb1,Nfkb2,Pdlim7,Ikbkg,Traf1,Tnf |
| 1.286e-03 | -6.66 | GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_UP | MSigDB lists | GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_UP | 182 | 27 | 15632 | 1249 |
Usp18,Zc3hav1,Rbm43,Fbxo4,1600014C10Rik,Arhgef3,Tet2,Slc25a37,Tra2a,Igsf6,Rnf24,Dnajb4,Smox,Sema4c,Ifi35,Itga5,Oasl1,Vegfc,5430427O19Rik,Dnajb2,Osm,Lcn2,Hsd17b12,Abtb2,Ext1,Akt3,Slc2a6 |
| 1.286e-03 | -6.66 | GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_UP | MSigDB lists | GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_UP | 182 | 27 | 15632 | 1249 |
Phlpp1,Cers6,Pdpn,Rhof,Eno1,Plac8,Ifit2,Armcx6,Rapgef5,Sgms2,Sdc1,Mcm10,Hivep3,Met,Fzd1,Klf2,Dmwd,Mthfd1l,Jarid2,Dusp6,Dio2,Prkar2b,Pcdh7,Ppp2r1b,Sema4a,Cpeb4,Uchl1 |
| 1.286e-03 | -6.66 | GSE22886_NAIVE_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NKCELL_DN | 182 | 27 | 15632 | 1249 |
Aoah,Ifi213,Ifi209,Tcf4,Ifi205,Arhgef3,Rhoq,Rab11fip1,Cebpd,Ifi214,Sla,Ifi207,Notch1,Crim1,Cdyl,Jarid2,Mndal,Lcn2,Ifi208,Ifi211,Il18rap,Ifi203,Atp10a,Map3k8,Ifi204,Inpp1,Cflar |
| 1.286e-03 | -6.66 | GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_UP | MSigDB lists | GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_UP | 182 | 27 | 15632 | 1249 |
Traf5,Gclc,Prnp,Sell,P2ry14,Il4ra,Hhex,Ccr3,Bnip3,Dusp2,Ly75,Itpr1,Swap70,Srm,Wdr43,Clcn7,Ccl4,Map3k8,H2-Ab1,Cd55,Traf3ip2,Slc39a14,Eef1e1,Txn1,Plek,Birc3,Map4k4 |
| 1.286e-03 | -6.66 | GSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | 182 | 27 | 15632 | 1249 |
Met,Ikbkg,Rgl1,Psat1,Plk2,Bambi,Clic4,Clcf1,Rbms1,Zcchc2,Esd,Dusp5,Mmp9,Stap1,Itgb8,Gypc,Abcc5,Zswim4,Hmga1,Bcl6,Slc48a1,Ube2f,F10,Slc25a25,Clcn5,Nck1,Nxf1 |
| 1.286e-03 | -6.66 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_DN | 182 | 27 | 15632 | 1249 |
Ebi3,Nr4a3,Fam20c,Whamm,Sesn3,Card6,Rgl1,Cep350,Hopx,H2-Aa,Trim14,Icosl,Ccrl2,Fas,Aldh1b1,Cd74,Kmo,Spata13,1600014C10Rik,Gys1,Cd38,Cd40,Bcl6,Ets2,Gpr18,Ccng2,Treml2 |
| 1.286e-03 | -6.66 | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_UP | MSigDB lists | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_UP | 182 | 27 | 15632 | 1249 |
Frmd6,Pkp4,Hcls1,Pilrb1,Pdzd11,Ell2,Hivep3,Gem,Cnp,Dusp6,Psmb8,Dusp14,Ahr,Slc28a2,Cd38,Pilrb2,Pim3,Fgr,P2ry14,Dcp2,Ubash3b,Gadd45g,Arhgap26,Acpp,Swap70,Mrpl52,Lipe |
| 1.286e-03 | -6.66 | GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_UP | MSigDB lists | GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_UP | 182 | 27 | 15632 | 1249 |
Ptpn2,Syk,Casp1,Rin2,Dbnl,Nxf1,Atp11a,Icam1,Mapkapk2,Tap1,Relb,Gpc1,Rnf34,Myd88,Ogfr,Hopx,Ccl5,Eif4g2,Kctd12,Il18rap,G3bp2,H2-Aa,Ext1,Nsmaf,Ell2,Mmp9,Cd82 |
| 1.286e-03 | -6.66 | GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_UP | MSigDB lists | GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_UP | 182 | 27 | 15632 | 1249 |
Lif,Pgs1,Tulp3,Cd14,Cd80,1600014C10Rik,Mdfic,Aff1,Plac8,Swap70,Timp1,Cebpd,Ift57,Mdm2,Parp3,Zc3h12a,Uchl1,Cox18,Tax1bp1,Lnpep,Sesn3,Gem,Rims3,Gpr132,Cysltr2,Etv6,Car13 |
| 1.286e-03 | -6.66 | GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_DN | MSigDB lists | GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_DN | 182 | 27 | 15632 | 1249 |
Ccnd1,Fgl2,Cebpd,Dusp1,Klf6,Axl,Itpr1,Jun,Serp1,Csf3r,Rgs3,Ier2,Egr1,Ccnd2,Xrn1,Ociad1,Zfp36,Timeless,Ccrl2,Junb,Dusp6,Klf2,Fosb,Kitl,Igf1r,Ptk2,Adrb2 |
| 1.286e-03 | -6.66 | GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | MSigDB lists | GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | 182 | 27 | 15632 | 1249 |
Sec24b,Pkp4,Pcdh7,Irf1,Dnajb4,Ppa1,Sema4c,Fam53c,Kctd12,Jag1,Hivep3,Pdss1,Tmeff1,Zc3h7a,Pstpip2,Irf8,Gbp2,Gclc,Col4a2,Il15,Vcan,Ctsc,Gclm,Bcl6,Cited2,Psip1,Abcc5 |
| 1.286e-03 | -6.66 | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_DN | 182 | 27 | 15632 | 1249 |
Il1a,Prdm1,Tnks1bp1,Hinfp,Eif2ak2,Bcl2a1b,Bcl2a1d,Nqo1,Cish,Mmp14,Dusp8,Acsl1,Ptprj,Xcr1,Bcl2a1a,Clic4,Serpinb2,Tnfsf10,Lcn2,Gem,Slc4a7,Csrp1,Gja1,Ccl5,Ccrl2,Csf1,Plscr1 |
| 1.287e-03 | -6.66 | positive regulation of anion transport | biological process | GO:1903793 | 65 | 12 | 20694 | 1406 |
Nr3c1,Il1b,Kmo,Acsl5,Fabp3,Ptafr,Edn1,Stxbp1,Abcb1a,Adora2a,Il1a,P2ry2 |
| 1.289e-03 | -6.65 | GO_CELLULAR_TRANSITION_METAL_ION_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_TRANSITION_METAL_ION_HOMEOSTASIS | 71 | 14 | 15632 | 1249 |
Myc,Slc39a4,Cp,Slc39a14,S100a8,Slc31a2,Sco1,Lcn2,Slc31a1,Hmox1,Slc39a13,Prnp,Hif1a,Slc30a1 |
| 1.294e-03 | -6.65 | integrin binding | molecular function | GO:0005178 | 128 | 19 | 20217 | 1400 |
Kdr,Mmp14,Cx3cl1,Thbs1,Lyn,S1pr2,Isg15,Ptpn2,Vcam1,Itgav,Src,Plpp3,Itga5,Icam1,Ptk2,Il1b,Itgb8,Syk,Tgfbi |
| 1.294e-03 | -6.65 | GSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN | MSigDB lists | GSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN | 173 | 26 | 15632 | 1249 |
Psd4,Casp8,Gna15,Ext1,Maff,Inhba,H2-Ab1,Ak4,Sec24a,Serpinb2,Nfil3,Abcc1,Slc16a3,Cst7,Bcl6,Trip10,Cp,Gclm,Bnip3,Phactr4,Irf2,Kat2b,Htr2a,Ppfibp1,Clcn5,Cd38 |
| 1.294e-03 | -6.65 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_UP | 173 | 26 | 15632 | 1249 |
Pdpn,Pnp2,Vcan,Ppfia3,Dusp4,Dpy19l1,P4ha2,Srm,Homer1,Rras2,Cd83,Slc28a2,Hlx,Ier2,Marcksl1,Ch25h,Aldh1b1,Socs1,Slc39a14,Pde4b,Nfkb1,Rel,Plod2,Egr3,Tgfbi,Rcan1 |
| 1.294e-03 | -6.65 | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN | 173 | 26 | 15632 | 1249 |
Irgq,Rab21,Lrch1,Eif2ak2,Sod2,Pik3r5,Plod3,Adar,Mcmbp,Slco3a1,Cdk5r1,Socs1,Gbe1,Jmjd6,Btg2,Phlda1,Zfp36,Ccl4,Ikbke,Rnf19b,Atp10a,Dnaja2,Fndc3a,Trib1,Nsmaf,Mthfd2 |
| 1.294e-03 | -6.65 | GSE29949_MICROGLIA_VS_DC_BRAIN_DN | MSigDB lists | GSE29949_MICROGLIA_VS_DC_BRAIN_DN | 173 | 26 | 15632 | 1249 |
Stx11,Cxcl2,Adora2a,Trim21,Lmo4,Serpine1,Casp8,Irf7,Ppfibp2,Gcnt2,Tnfsf10,H2-Ab1,Socs3,Gng4,Dtnb,Ccl2,Itgb8,Tnfsf8,Bcl6,Ptpn2,Gadd45b,Cd38,P2ry14,Slc30a4,Nfkbil1,Col18a1 |
| 1.295e-03 | -6.65 | GCNP_SHH_UP_LATE.V1_DN | MSigDB lists | GCNP_SHH_UP_LATE.V1_DN | 164 | 25 | 15632 | 1249 |
Cx3cl1,Il4ra,Sell,Agtrap,Ncoa7,Cnn2,Parp8,Slc2a1,Ikzf1,Tbc1d1,Edn1,Sat1,Acvr1,Ptprj,Ebi3,Ptger4,Adrb2,Fam111a,Sh3bgrl2,Vegfc,Ikbkg,Psmb8,Zc3h12c,Nmi,Nrp2 |
| 1.298e-03 | -6.65 | Oxidative Damage | WikiPathways | WP1496 | 41 | 12 | 4813 | 540 |
Casp3,Tnfrsf1b,Apaf1,Traf1,Map2k4,Cycs,Tnf,Cdkn1a,Nfkb1,Nfkbie,C1ra,Traf2 |
| 1.298e-03 | -6.65 | positive regulation of lipid biosynthetic process | biological process | GO:0046889 | 92 | 15 | 20694 | 1406 |
Ldlr,Il1b,Pla2g4a,Nr1h3,Adora2b,Fpr2,Fabp3,Acsl5,Htr2a,Tnf,Ptgs2,Il1a,Pcx,Htr2b,Igf1r |
| 1.306e-03 | -6.64 | TNF_2 | prosite domains | PS50049 | 17 | 6 | 13278 | 1037 |
Tnfsf14,Tnfsf8,Tnfsf10,Tnf,Tnfsf9,Tnfsf15 |
| 1.306e-03 | -6.64 | INTERFERON_A_B_D | prosite domains | PS00252 | 17 | 6 | 13278 | 1037 |
Ifna4,Ifnb1,Ifna5,Ifna2,Ifna6,Ifna1 |
| 1.306e-03 | -6.64 | GO_CHEMICAL_HOMEOSTASIS | MSigDB lists | GO_CHEMICAL_HOMEOSTASIS | 823 | 90 | 15632 | 1249 |
Slc31a2,Slc4a7,Slc7a8,Ifit1bl2,Hk2,Oas1g,Ptger4,Cd55,Grina,Clic4,Ehd1,Cd40,Itpr1,Swap70,Atp13a1,Pml,Slc30a4,Icam1,Hif1a,Pdk3,Ptch1,P2ry2,Lcn2,Gna15,Slc39a14,Oas1a,Sirt1,Stat1,Nox1,Mafg,Prkar2b,Xcr1,Ccl12,Ifit1bl1,Prkce,Il6,Ccl2,Myc,Kcnj2,Ccr3,Edn1,Ncoa5,Tmtc2,Prnp,Htr2a,Plau,Tap1,Atp2b4,Ccl5,Gja1,Ccr1,Atp6v1d,Tap2,Hmox1,Slc31a1,Htr2b,Il1b,Slc25a37,Homer1,Slc39a4,Cp,Stat3,Fabp3,Slc39a13,Lipg,Cutc,Sgk3,Cd38,Stau1,Ednrb,Hk1,S100a8,Sco1,Cav1,Med13,Slc9a1,Rab20,Lpar1,Cacnb3,Ldlr,Jak2,Sod2,Ptpn2,Pla2g4a,Fas,Irs2,Slc30a1,Nr1h3,Slc16a1,Hk3 |
| 1.312e-03 | -6.64 | KRAS.600.LUNG.BREAST_UP.V1_UP | MSigDB lists | KRAS.600.LUNG.BREAST_UP.V1_UP | 238 | 33 | 15632 | 1249 |
Mmp9,Kif5c,Ptgs2,Cmklr1,Cxcl1,Adam19,Plaur,Dcbld2,Glrx,Gfi1,Il1b,Birc3,Ppp1r15a,Isg20,Tnfsf15,Inhba,Csf3,Cxcl2,Prdm1,Tmem176b,Lif,Ccl22,Sphk1,St3gal6,Traf1,Gng11,Fbxo4,Bmp2,Tnfaip3,Dhrs9,Gypc,Dock4,Spry2 |
| 1.316e-03 | -6.63 | GAVIN_FOXP3_TARGETS_CLUSTER_P6 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P6 | 87 | 16 | 15632 | 1249 |
Irf8,Cst7,Cenpe,Il12rb1,Slc39a4,Ifi44,Abcb1a,Ksr1,Cysltr2,Tpx2,Icam1,Odc1,Tpi1,Mcm10,Ebi3,Cmpk2 |
| 1.316e-03 | -6.63 | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 87 | 16 | 15632 | 1249 |
Txn1,Nfkbia,Psmd10,Il10,Nfkbib,Fzd1,G3bp2,Nfkbie,Zc3h12a,Dyrk2,Parp10,Nfkbil1,Nlrp3,Angpt1,Keap1,Mdfic |
| 1.316e-03 | -6.63 | GCTCTTG_MIR335 | MSigDB lists | GCTCTTG_MIR335 | 79 | 15 | 15632 | 1249 |
Rsbn1,Igf2bp2,Stard7,Crim1,Naa25,Crkl,Max,Trim13,Nr4a3,Slc9a1,Glipr2,Abcc5,Dcun1d3,Tpst1,Cep350 |
| 1.316e-03 | -6.63 | GO_MOVEMENT_IN_ENVIRONMENT_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION | MSigDB lists | GO_MOVEMENT_IN_ENVIRONMENT_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION | 79 | 15 | 15632 | 1249 |
Hspa1a,Cd86,Cav1,Itgav,Axl,Tnfrsf14,Cd80,Ldlr,Htr2a,F11r,Icam1,Clec5a,Itga5,Cd55,Kpna3 |
| 1.322e-03 | -6.63 | Jak2 (Janus kinase 2) | protein interactions | 16452 | 35 | 10 | 7778 | 753 |
Lyn,Cav1,Stat5a,Lmo4,Stat3,Ubash3b,Socs1,Src,Socs3,Jak2 |
| 1.323e-03 | -6.63 | BURTON_ADIPOGENESIS_PEAK_AT_0HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_0HR | 56 | 12 | 15632 | 1249 |
Pdgfrb,Klf2,Ube2l6,Csf1,Ccng2,Isg15,Psmb10,Serpinb9,Trib3,Ralgds,Plat,Vegfc |
| 1.323e-03 | -6.63 | SCHEIDEREIT_IKK_INTERACTING_PROTEINS | MSigDB lists | SCHEIDEREIT_IKK_INTERACTING_PROTEINS | 56 | 12 | 15632 | 1249 |
Ccnd1,Src,Eif2ak2,Atm,Casp8,Tank,Irf7,Traf2,Tnfaip3,Traf3ip2,Map3k8,Traf1 |
| 1.328e-03 | -6.62 | negative regulation of protein ubiquitination | biological process | GO:0031397 | 74 | 13 | 20694 | 1406 |
Dnaja1,Gbp4,Prkce,Tspo,Tnfaip3,Cav1,Dtx3l,Svbp,N4bp1,Caml,Parp10,Gclc,Isg15 |
| 1.328e-03 | -6.62 | regulation of ATPase activity | biological process | GO:0043462 | 74 | 13 | 20694 | 1406 |
Dnajb2,Dnaja2,Dnaja1,Tor1aip1,Hspa2,Dnajb4,Zc3hav1,Cnn3,Ahsa1,Adrb2,Plscr1,Sirt1,Tor1aip2 |
| 1.328e-03 | -6.62 | stress-activated MAPK cascade | biological process | GO:0051403 | 83 | 14 | 20694 | 1406 |
Trib1,Ripk2,Mul1,Mdfic,Mapkbp1,Tnf,Syk,Ptger4,Ptk2,Mapkapk2,Map2k4,Mlkl,Myd88,Zfp36 |
| 1.336e-03 | -6.62 | regulation of T cell differentiation in thymus | biological process | GO:0033081 | 33 | 8 | 20694 | 1406 |
Egr3,Ptpn2,Rasgrp1,Zeb1,Il1b,Il2rg,Nfkbid,Lgals9 |
| 1.336e-03 | -6.62 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib | biological process | GO:0002476 | 33 | 8 | 20694 | 1406 |
H2-T24,H2-T10,H2-M2,H2-T22,H2-Q6,H2-Q4,Tap2,H2-Q7 |
| 1.336e-03 | -6.62 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway | biological process | GO:0002484 | 33 | 8 | 20694 | 1406 |
H2-Q6,H2-T22,H2-Q7,H2-Q4,Tap2,H2-T24,H2-M2,H2-T10 |
| 1.336e-03 | -6.62 | acute-phase response | biological process | GO:0006953 | 33 | 8 | 20694 | 1406 |
Il1a,Il1rn,Saa3,Il1b,Hp,Plscr1,Stat3,Il6 |
| 1.336e-03 | -6.62 | regulation of platelet activation | biological process | GO:0010543 | 33 | 8 | 20694 | 1406 |
Lyn,Pdpn,Ptprj,Adrb2,Syk,Ubash3b,Pdgfb,Plek |
| 1.336e-03 | -6.62 | positive regulation of lipid kinase activity | biological process | GO:0090218 | 33 | 8 | 20694 | 1406 |
Pdgfrb,Flt1,Src,Fgr,Fpr2,Lyn,Nod2,Pdgfb |
| 1.336e-03 | -6.62 | positive regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0045737 | 33 | 8 | 20694 | 1406 |
Src,Ccnd2,Pdgfb,Rgcc,Psmd10,Cdk5r1,Pim1,Ccnd1 |
| 1.336e-03 | -6.62 | Tlr4 (toll-like receptor 4) | protein interactions | 21898 | 24 | 8 | 7778 | 753 |
Birc2,Wdfy1,Birc3,Myd88,Syk,Il10,Cd14,Ikbkg |
| 1.345e-03 | -6.61 | negative regulation of cellular catabolic process | biological process | GO:0031330 | 235 | 29 | 20694 | 1406 |
Htr2b,Timp1,Larp1,Tent2,Hmox1,Nupr1,Tnfaip3,Zfp36,Chmp4b,Mapkapk2,Ptk2,Hp,Atp2b4,Kdm4a,Usp25,Ric1,Tent4a,Tspo,Myd88,Noct,Stat3,N4bp1,Eif4g2,Caml,Tlk2,Sco1,Nampt,Pml,Il10 |
| 1.350e-03 | -6.61 | L-ascorbic acid binding | molecular function | GO:0031418 | 19 | 6 | 20217 | 1400 |
Plod2,P4ha1,P4ha2,Phyh,Egln3,Plod3 |
| 1.351e-03 | -6.61 | plasma membrane protein complex | cellular component | GO:0098797 | 534 | 55 | 20747 | 1409 |
Calcrl,Itgav,Rnf31,Mpp7,H2-Q4,Traf5,Cd74,Gnb4,Itga5,H2-Q7,Casp3,Gja1,Gng11,Syk,Gna15,Tlr6,Traf2,Lyn,Itga4,Cd40,H2-Q6,Casp8,Cflar,H2-Aa,Tlr1,Kcna3,Gng12,Itgal,Il6,Cacna1d,Tlr2,Nox1,Itgb8,Ebi3,Itga9,Pde4b,Fcho2,Scn1b,Il12rb1,H2-Ab1,Birc2,Il18rap,Kcnj2,Gng4,Acvr1b,Sgcb,Igf1r,Cacnb3,Vcam1,Hspa2,Acvrl1,Acvr1,H2-Eb1,Fas,Bmp2 |
| 1.355e-03 | -6.60 | GO_RESPONSE_TO_VITAMIN_D | MSigDB lists | GO_RESPONSE_TO_VITAMIN_D | 35 | 9 | 15632 | 1249 |
Cdkn2d,Cxcl10,Pim1,Ptgs2,Tnc,Il15,Pla2g4a,Il1b,Fzd1 |
| 1.355e-03 | -6.60 | GO_NADH_METABOLIC_PROCESS | MSigDB lists | GO_NADH_METABOLIC_PROCESS | 35 | 9 | 15632 | 1249 |
Pfkfb3,Hk3,Pfkl,Hk2,Pgk1,Eno2,Hk1,Tpi1,Eno1 |
| 1.355e-03 | -6.60 | GO_REGULATION_OF_LYMPHOCYTE_MIGRATION | MSigDB lists | GO_REGULATION_OF_LYMPHOCYTE_MIGRATION | 35 | 9 | 15632 | 1249 |
Ccl4,Cxcl14,Ripk3,Tnfrsf14,Ccl5,Ccl12,Itga4,Cxcl10,Tnfsf14 |
| 1.355e-03 | -6.60 | GO_PEPTIDASE_ACTIVATOR_ACTIVITY | MSigDB lists | GO_PEPTIDASE_ACTIVATOR_ACTIVITY | 35 | 9 | 15632 | 1249 |
Casp1,Psme1,Cav1,Psme2,Mmp14,Nod1,Ctsc,Casp3,Apaf1 |
| 1.358e-03 | -6.60 | GO_LIGASE_ACTIVITY | MSigDB lists | GO_LIGASE_ACTIVITY | 375 | 47 | 15632 | 1249 |
Egr2,Rffl,Mdm2,Traf2,Birc2,Rnf34,Ube2f,Tnfaip3,Rnf139,Trim12c,Dtx3l,Rnf135,Wars,Uba7,Mthfd1l,Asns,Acsl5,Rcl1,Rnf19b,Herc6,Uchl1,Parp3,Gclm,Peli1,Cnot4,Pcx,Mid1,Trim36,Rnf114,Ass1,Herc3,Gclc,Rars,Trim13,Znrf3,Mul1,Trim21,Rnf19a,Trim56,Birc3,Rnf31,Rnf14,Ubr4,Znrf1,Dtx2,Mthfd2,Acsl1 |
| 1.365e-03 | -6.60 | phosphoprotein binding | molecular function | GO:0051219 | 100 | 16 | 20217 | 1400 |
Pde3b,Lyn,Stap1,Acp2,Fgr,Samsn1,Crkl,Socs3,Plat,Ubash3b,Hck,Src,Mid1,Lrp11,Syk,Phf6 |
| 1.368e-03 | -6.59 | organic cyclic compound catabolic process | biological process | GO:1901361 | 324 | 37 | 20694 | 1406 |
Hmox1,Zhx2,Gsta3,Xrn1,Tent2,Helz2,Kmo,Enpp4,Polr2g,Gda,Tet2,Dcp1a,Zc3h12a,Zfp36,Pde5a,Dnase1l3,Oas2,Mgat1,Pnpt1,Magohb,Apobec3,Tent4a,Atm,Hdc,Upp1,Samhd1,Ago3,Smg7,Rnaset2a,Dio2,Isg20,Cnp,Noct,Gtpbp2,Slfn8,Dcp2,Tut7 |
| 1.368e-03 | -6.59 | GSE40274_EOS_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_EOS_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 138 | 22 | 15632 | 1249 |
Usp35,Rapgef2,Ctsc,Irgq,Mgat1,Tnfsf14,Cacybp,Gch1,Rnf31,Ccr1,Pmepa1,Gfi1,Glrx,Crim1,Slc16a1,Cldnd1,Gys1,Ust,Nod1,Cdc42ep4,Azi2,Jmjd6 |
| 1.368e-03 | -6.59 | BIDUS_METASTASIS_DN | MSigDB lists | BIDUS_METASTASIS_DN | 138 | 22 | 15632 | 1249 |
Rgl1,Itgal,Plekha2,Ep400,Hp,Dram1,Ms4a6d,Frmd4a,Cflar,Ehd1,Gsdmd,Slc25a37,Gypc,Syk,Rin2,Parp10,Rnd1,Cd34,Sla,Ahr,Mvp,Ppfibp1 |
| 1.372e-03 | -6.59 | neural tube formation | biological process | GO:0001841 | 131 | 19 | 20694 | 1406 |
Sdc4,Casp8,Mthfd1l,Lhx2,Sec24b,Ift57,Apaf1,Vasp,Fzd1,Ptch1,Lmo4,Mthfr,Casp3,Hif1a,Sema4c,Spint2,Cited2,Phactr4,Tulp3 |
| 1.376e-03 | -6.59 | myeloid dendritic cell activation | biological process | GO:0001773 | 26 | 7 | 20694 | 1406 |
Batf2,Notch2,Relb,Tnfsf9,Irf4,Batf,Pilrb1 |
| 1.376e-03 | -6.59 | mature B cell differentiation | biological process | GO:0002335 | 26 | 7 | 20694 | 1406 |
Tnfaip3,Notch2,Dock10,Slamf8,Plcl2,Pou2f2,Malt1 |
| 1.376e-03 | -6.59 | regulation of T-helper 17 type immune response | biological process | GO:2000316 | 26 | 7 | 20694 | 1406 |
Malt1,Zc3h12a,Arid5a,Nlrp3,Lgals9,Nfkbid,Nfkbiz |
| 1.376e-03 | -6.59 | negative regulation of receptor signaling pathway via STAT | biological process | GO:1904893 | 26 | 7 | 20694 | 1406 |
Parp14,Cav1,Hmga2,Socs1,Socs3,Irf1,Ptpn2 |
| 1.376e-03 | -6.59 | positive regulation of phospholipase C activity | biological process | GO:0010863 | 26 | 7 | 20694 | 1406 |
Lpar1,Sele,Htr2a,Flt1,Pdgfrb,Htr2b,Ptafr |
| 1.378e-03 | -6.59 | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP | 192 | 28 | 15632 | 1249 |
Ppp2r5a,Fcgr2b,Ttc39c,H2-Q6,Pik3r5,Insl6,Cx3cr1,Hsph1,H2-Q4,Klf3,Nod1,Slco3a1,Icam1,H2-Q7,Evl,Il18rap,Tyk2,Rap1gap2,Rasgrp1,Hopx,Klf2,Card6,Ap3m2,Prkx,Tnip1,Orai2,Adrb2,Smox |
| 1.384e-03 | -6.58 | Proteasome_activ_PA28_N | interpro domains | IPR003185 | 4 | 3 | 19984 | 1430 |
Psme1,Psme2b,Psme2 |
| 1.384e-03 | -6.58 | Syndecan | interpro domains | IPR001050 | 4 | 3 | 19984 | 1430 |
Sdc4,Sdc1,Sdc2 |
| 1.384e-03 | -6.58 | PA28_N_sf | interpro domains | IPR036996 | 4 | 3 | 19984 | 1430 |
Psme2b,Psme1,Psme2 |
| 1.384e-03 | -6.58 | PA28_C | interpro domains | IPR003186 | 4 | 3 | 19984 | 1430 |
Psme1,Psme2b,Psme2 |
| 1.384e-03 | -6.58 | Proteasome_activ_PA28 | interpro domains | IPR009077 | 4 | 3 | 19984 | 1430 |
Psme1,Psme2b,Psme2 |
| 1.384e-03 | -6.58 | Syndecan_CS | interpro domains | IPR030479 | 4 | 3 | 19984 | 1430 |
Sdc1,Sdc4,Sdc2 |
| 1.384e-03 | -6.58 | Proteasome_activ_sf | interpro domains | IPR036252 | 4 | 3 | 19984 | 1430 |
Psme1,Psme2b,Psme2 |
| 1.384e-03 | -6.58 | Tribbles/Ser_Thr_kinase_40 | interpro domains | IPR024104 | 4 | 3 | 19984 | 1430 |
Trib3,Trib1,Stk40 |
| 1.384e-03 | -6.58 | PA28_C_sf | interpro domains | IPR036997 | 4 | 3 | 19984 | 1430 |
Psme2,Psme1,Psme2b |
| 1.384e-03 | -6.58 | cNuc_Pdiesterase | interpro domains | IPR009097 | 4 | 3 | 19984 | 1430 |
Cnp,Leng9,Usb1 |
| 1.384e-03 | -6.58 | Bcl2A1 | interpro domains | IPR013282 | 4 | 3 | 19984 | 1430 |
Bcl2a1a,Bcl2a1d,Bcl2a1b |
| 1.384e-03 | -6.58 | WH1 | smart domains | SM00461 | 11 | 5 | 9567 | 823 |
Spred1,Evl,Vasp,Spred3,Homer1 |
| 1.392e-03 | -6.58 | YU_MYC_TARGETS_DN | MSigDB lists | YU_MYC_TARGETS_DN | 49 | 11 | 15632 | 1249 |
Dgka,H2-Aa,Slfn4,Klf2,Klf3,Slfn3,Rbms1,Gbp3,Cd74,Evl,H2-Ab1 |
| 1.392e-03 | -6.58 | GO_ENDODERM_FORMATION | MSigDB lists | GO_ENDODERM_FORMATION | 49 | 11 | 15632 | 1249 |
Dusp1,Itga4,Dusp5,Itgav,Mmp9,Itga5,Col4a2,Mmp14,Dusp2,Inhba,Dusp4 |
| 1.394e-03 | -6.58 | Natural killer cell mediated cytotoxicity | KEGG pathways | mmu04650 | 116 | 21 | 7931 | 713 |
Pik3cd,Map2k1,Fcgr4,Ifna6,Ifnar1,Tnf,Icam1,Syk,Rac3,Lcp2,Ifna4,Fas,Ifna5,Ifna2,Ifnb1,Itgal,Ifna1,Raet1e,Tnfsf10,Casp3,Klrk1 |
| 1.394e-03 | -6.58 | Natural killer cell mediated cytotoxicity | KEGG pathways | ko04650 | 116 | 21 | 7931 | 713 |
Pik3cd,Map2k1,Ifna6,Fcgr4,Rac3,Lcp2,Tnf,Icam1,Syk,Ifnar1,Fas,Ifna5,Ifna4,Ifna2,Ifnb1,Raet1e,Tnfsf10,Itgal,Ifna1,Klrk1,Casp3 |
| 1.397e-03 | -6.57 | GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_DN | MSigDB lists | GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_DN | 183 | 27 | 15632 | 1249 |
Rab9,Ly75,Ift57,Plekha5,Nr4a1,Ptpn2,Rbbp8,Hmga1,Slamf7,Pde3b,Slc16a1,Batf,Ppfibp1,Rhoh,Arl4a,Sass6,Dcp2,Fam133b,Ksr1,Sik3,Gca,Dek,Cacna1d,Dnaja2,Nr4a3,Ttc39b,Osgin2 |
| 1.397e-03 | -6.57 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN | 183 | 27 | 15632 | 1249 |
Sap30,Phlda1,Slc7a5,Timeless,Cnp,Tspan3,Il10,Lap3,Ascc3,Dpy19l1,Pdk3,Lnpep,Hk3,Pkp4,Nfil3,Gfi1,Cdkn1a,Sla,Ccl4,Idi1,Slc43a3,Pttg1,Psmb10,Mthfd2,Ifi35,Ptgir,Cd200 |
| 1.397e-03 | -6.57 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | 183 | 27 | 15632 | 1249 |
Gbp7,Tnfsf14,Irf8,Hivep3,Plscr1,Map3k8,Frmd4a,Rcan1,Pcgf5,Atp10a,Gfi1,Il15ra,Znrf1,Tcf4,Arhgef3,Plekha5,Cst7,Ccl12,Spn,Ehd1,Nqo1,Ccnd2,Bcor,Mcoln2,Plk3,Tle3,Pnpt1 |
| 1.397e-03 | -6.57 | GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_DN | MSigDB lists | GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_DN | 183 | 27 | 15632 | 1249 |
Tnfsf10,Gcnt2,Irak2,Pim2,Grina,Piezo1,Wdfy1,AA467197,Il18rap,Tshz1,Tap2,Gpc1,Sdc4,Sgcb,Plagl2,Relb,Irak3,Etv5,Tpi1,Evl,Prdm1,Ciapin1,Pgm1,Glipr2,Aebp2,Optn,Arid5a |
| 1.397e-03 | -6.57 | Epor (erythropoietin receptor) | protein interactions | 13857 | 10 | 5 | 7778 | 753 |
Jak2,Stat5a,Cish,Crkl,Lyn |
| 1.397e-03 | -6.57 | Ube2d3 (ubiquitin-conjugating enzyme E2D 3) | protein interactions | 66105 | 10 | 5 | 7778 | 753 |
Tnfaip3,Rnf31,Mdm2,Traf2,Tax1bp1 |
| 1.397e-03 | -6.57 | Sumo1 (small ubiquitin-like modifier 1) | protein interactions | 22218 | 10 | 5 | 7778 | 753 |
Irf8,Junb,Daxx,Jun,Irf1 |
| 1.398e-03 | -6.57 | RHODANESE_3 | prosite domains | PS50206 | 23 | 7 | 13278 | 1037 |
Dusp1,Dusp8,Dusp5,Dusp4,Dusp16,Dusp2,Dusp6 |
| 1.398e-03 | -6.57 | TIR | prosite domains | PS50104 | 23 | 7 | 13278 | 1037 |
Tlr1,Tlr9,Il18rap,Myd88,Tlr2,Tlr6,Tlr3 |
| 1.406e-03 | -6.57 | GO_PROTEIN_SECRETION | MSigDB lists | GO_PROTEIN_SECRETION | 104 | 18 | 15632 | 1249 |
Pou2f2,Nod2,Pnp2,Stxbp3,Nos2,Lcp2,Nlrc4,Ltbp2,Plek,Notch1,Trem1,Il1rn,Tlr2,Lyn,Nlrp3,Traf3ip2,Tlr6,Aim2 |
| 1.406e-03 | -6.57 | GO_CELL_CYCLE_G1_S_PHASE_TRANSITION | MSigDB lists | GO_CELL_CYCLE_G1_S_PHASE_TRANSITION | 104 | 18 | 15632 | 1249 |
Gfi1,Cdkn1a,Hinfp,Crlf3,Acvr1b,Mcm6,Mcm10,Plk3,Cdkn2d,Pim2,Inhba,Ccnd1,Acvr1,Rhou,Gpr132,Plk2,Rbbp8,Ccne1 |
| 1.406e-03 | -6.57 | ZHANG_TLX_TARGETS_UP | MSigDB lists | ZHANG_TLX_TARGETS_UP | 104 | 18 | 15632 | 1249 |
Gadd45g,Ddit4,Srxn1,Csf1,Sat1,Btg2,Cited2,Gadd45b,Nr4a1,Tap1,Cdkn1a,Sp110,Ralgds,Nfkb2,Rnf145,Slco3a1,Sphk1,Parp3 |
| 1.409e-03 | -6.56 | GSE27786_NKTCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_NKTCELL_VS_NEUTROPHIL_UP | 174 | 26 | 15632 | 1249 |
Atp10a,Odc1,Phf6,Tnfsf10,Rgs1,Jak2,Ppp2r2a,Pfkl,Ptch1,Nmi,Inpp5b,Eef1e1,Pml,Slc30a1,Coa5,Tap1,Tnfaip3,Zc3hav1,Psip1,Ccdc86,Setdb2,Mdn1,Parp9,Taf4b,Aebp2,Lztfl1 |
| 1.409e-03 | -6.56 | GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_UP | 174 | 26 | 15632 | 1249 |
Bcl6,Jun,Gpr18,Parp8,Bbx,Myc,Rab11fip1,Psme1,Evl,Rgs3,Ccdc88b,Irf7,Lcp2,Card6,Brd2,Dach1,Zfp36,Gpr132,Egr3,Max,Sp110,Inpp1,Ikbke,Nfkb2,Tnip1,Orai2 |
| 1.412e-03 | -6.56 | PA28_beta | pfam domains | PF02252 | 4 | 3 | 18711 | 1348 |
Psme2b,Psme1,Psme2 |
| 1.412e-03 | -6.56 | PA28_alpha | pfam domains | PF02251 | 4 | 3 | 18711 | 1348 |
Psme2b,Psme1,Psme2 |
| 1.412e-03 | -6.56 | WANG_TARGETS_OF_MLL_CBP_FUSION_UP | MSigDB lists | WANG_TARGETS_OF_MLL_CBP_FUSION_UP | 42 | 10 | 15632 | 1249 |
Cpd,Ogfrl1,Cd14,Gpc1,F10,Gtpbp2,Vcam1,Cep350,P2ry14,Ezr |
| 1.412e-03 | -6.56 | GO_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN | MSigDB lists | GO_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN | 42 | 10 | 15632 | 1249 |
Lyn,Serpine1,Swap70,Syk,Rac3,Ccl5,Ptk2,Pde3b,Piezo1,Plau |
| 1.412e-03 | -6.56 | KLEIN_TARGETS_OF_BCR_ABL1_FUSION | MSigDB lists | KLEIN_TARGETS_OF_BCR_ABL1_FUSION | 42 | 10 | 15632 | 1249 |
Ikzf1,Irf4,Myd88,Cd38,Pml,Syk,Gypc,Cd40,Csf3r,Itgal |
| 1.413e-03 | -6.56 | CAGTGTT_MIR141_MIR200A | MSigDB lists | CAGTGTT_MIR141_MIR200A | 287 | 38 | 15632 | 1249 |
Nrp2,Tmeff1,Phlpp2,Stat4,Sirt1,Csf3,Nampt,Ppp1r15b,Dcun1d3,Cnp,Dmwd,Rbms1,Dek,Dr1,Chd9,Rap2c,Igf2bp2,Glrx,Frmd6,Ppp2r2a,Kpna3,Mob3b,Ak4,Rnf145,Frmd4a,Map2k4,Kcnj2,Mecp2,Errfi1,Phlpp1,Cpd,Stat5a,Src,Jun,Plagl2,St3gal3,Stxbp1,Irs2 |
| 1.413e-03 | -6.56 | GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION | MSigDB lists | GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION | 287 | 38 | 15632 | 1249 |
Icam1,F11r,Itga4,Col18a1,Ripk3,Kif9,Col4a2,Timp1,Tnf,Plod3,Agrn,Itgav,Vcan,Tnc,Mmp14,Itgb8,Itga9,Tgfbi,Lox,Ptk2,Nox1,Mmp9,Itga5,Vcam1,Thbs1,Kdr,Nfkb2,Col27a1,Flrt2,Itgal,Col11a2,Serpine1,Hsd17b12,P4ha1,Ltbp2,Mmp13,Pdgfb,Htra1 |
| 1.414e-03 | -6.56 | GO_CYTOPLASMIC_SIDE_OF_MEMBRANE | MSigDB lists | GO_CYTOPLASMIC_SIDE_OF_MEMBRANE | 165 | 25 | 15632 | 1249 |
Tyk2,Gna15,Gem,Rnf31,Pkp4,Gng12,Jak2,Rgs1,Lyn,Ptk2,Gng4,Errfi1,Rab21,Traf2,Dnaja1,Birc2,Src,Ezr,Syk,Chmp4b,Hck,Traf5,Gng11,Cyth3,Fgr |
| 1.414e-03 | -6.56 | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | 165 | 25 | 15632 | 1249 |
Gem,Plk2,Sesn3,Cd69,Flnb,Btg2,Nr4a3,Ell2,Herc6,Mtus1,Tnf,Ncoa5,Tnfsf8,Dusp2,Peli1,Mpp7,Dtx3l,Ubash3b,Csrnp1,Rhoh,Plk3,Prdm1,Tnfaip3,Cd83,Fbrsl1 |
| 1.414e-03 | -6.56 | GSE3982_NKCELL_VS_TH2_UP | MSigDB lists | GSE3982_NKCELL_VS_TH2_UP | 165 | 25 | 15632 | 1249 |
Nfkbil1,Enpp4,Hk3,Zbp1,Arhgef3,Aoah,Syk,Fchsd2,Frmd4a,Xkr8,Dram1,Agpat4,Vegfc,Snn,Il1b,Itgal,Rnf31,Ednrb,Ltbp2,Stoml1,Jag1,Syne2,Procr,Caml,Antxr1 |
| 1.414e-03 | -6.56 | GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP | MSigDB lists | GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP | 165 | 25 | 15632 | 1249 |
Vasp,Rhou,Oas1a,Slamf9,Cdyl,Rrs1,Cd82,Cmpk2,Stard7,Oas1g,Ttc39b,Pdzd11,Adora2b,I830077J02Rik,Glipr2,Tmem200b,Ifit2,Oas3,Nlrc4,Trp53i11,Atp11b,Clcn5,Rgs3,Arrdc4,Slco3a1 |
| 1.414e-03 | -6.56 | GO_CELLULAR_RESPONSE_TO_ACID_CHEMICAL | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ACID_CHEMICAL | 165 | 25 | 15632 | 1249 |
Pdgfc,Socs1,Hif1a,Egr1,Fas,Prkce,Edn1,Tnc,Ass1,Ccl12,Src,Tnf,Il1b,Ptafr,Lyn,Zc3h12a,Tnfsf4,Cpeb4,Ptger4,Sh3bp4,Pdgfb,Zeb1,Pid1,Ccl5,Pdk3 |
| 1.419e-03 | -6.56 | EPO Receptor Signaling | WikiPathways | WP1249 | 26 | 9 | 4813 | 540 |
Map2k1,Socs1,Stat3,Src,Cish,Jak2,Stat1,Irs2,Stat5a |
| 1.426e-03 | -6.55 | MODULE_33 | MSigDB lists | MODULE_33 | 346 | 44 | 15632 | 1249 |
Bcl6,Hck,Rgs3,Sell,Nfkbil1,Hk2,Tmeff1,Lad1,Ccl5,Gja1,Gdf15,Gch1,Ifit1bl2,4930523C07Rik,Pf4,Inpp1,Thbs1,Serpinb9,Ptafr,Cxcl10,Uchl1,Cpd,Dusp4,Ass1,Sod2,Tagln,Ifit1bl1,Tle3,Trp53i11,Pfkfb3,P2ry14,Arl4a,Mmd,Slpi,Plod2,Rims3,Ccne1,Lnpep,Tnfaip2,Cacnb3,Mmp9,Itga5,C3,Hmgcs1 |
| 1.439e-03 | -6.54 | GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | MSigDB lists | GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 498 | 59 | 15632 | 1249 |
Lif,Pml,Plk3,Nfkbil1,Parp10,Sphk1,Ddx58,Mdfic,Plagl2,Lrp4,Tnf,Hsph1,Rhoq,Micall2,Nfkbie,Rbpms,Lztfl1,Mdm2,Zc3h12a,Tlr3,Il12b,Il18,Ptgs2,Bambi,Keap1,Il1b,Txn1,Fzd5,Fzd1,Csf3,G3bp2,Cdk5r1,Nlrp3,Prdx1,Angpt1,Ccl12,Bcl2l11,Nfkbia,Ezr,Psmd10,Il6,Ppp2r5a,Dyrk2,Tlr9,Tlr2,Hcls1,Jak2,Cdkn1a,Stard7,Rnf31,Casp8,Il10,Pid1,Tnfsf14,Nfkbib,Slc9a1,Rhou,Stx6,Sirt1 |
| 1.446e-03 | -6.54 | TIR_dom | interpro domains | IPR000157 | 25 | 7 | 19984 | 1430 |
Tlr2,Tlr6,Myd88,Tlr1,Tlr3,Tlr9,Il18rap |
| 1.450e-03 | -6.54 | negative regulation of DNA biosynthetic process | biological process | GO:2000279 | 41 | 9 | 20694 | 1406 |
Dcp2,Gja1,Acvrl1,Dusp1,Src,Dach1,Parp3,Pml,Ahr |
| 1.450e-03 | -6.54 | negative regulation of endothelial cell proliferation | biological process | GO:0001937 | 41 | 9 | 20694 | 1406 |
Flt1,Acvrl1,Gja1,Stat1,Thbs1,Rgcc,Ccl12,Tnf,Cav1 |
| 1.450e-03 | -6.54 | regulation of viral transcription | biological process | GO:0046782 | 41 | 9 | 20694 | 1406 |
Hdac1,Ccl4,Trim21,Zfp36,Jun,Trim13,Trim14,Ccl5,Mdfic |
| 1.451e-03 | -6.54 | positive regulation of protein ubiquitination | biological process | GO:0031398 | 112 | 17 | 20694 | 1406 |
Fbxo4,Angpt1,Peli1,Arrdc4,Adrb2,Nmi,Birc3,Trib3,Birc2,Dcun1d3,Sphk1,Psmd10,Nod2,Dnajb2,Ripk2,Trib1,Cav1 |
| 1.453e-03 | -6.53 | T cell receptor signaling pathway | biological process | GO:0050852 | 93 | 15 | 20694 | 1406 |
Cacnb3,Spn,Rnf31,Pde4b,Icosl,Malt1,Zc3h12a,Nfkbiz,Crkl,Lcp2,Nfkbid,Bcl2a1d,Ripk2,Themis2,Dennd1b |
| 1.454e-03 | -6.53 | negative regulation of interleukin-6 production | biological process | GO:0032715 | 49 | 10 | 20694 | 1406 |
Rabgef1,Tnf,Cd200,Trim30a,Tnfaip3,Il10,Zc3h12a,Irak3,Klf2,Tlr9 |
| 1.454e-03 | -6.53 | negative regulation of epithelial cell apoptotic process | biological process | GO:1904036 | 49 | 10 | 20694 | 1406 |
Igf1r,Kdr,Angpt1,Tnfaip3,Serpine1,Cflar,Il10,Nupr1,Hmox1,Icam1 |
| 1.470e-03 | -6.52 | anatomical structure homeostasis | biological process | GO:0060249 | 314 | 36 | 20694 | 1406 |
Parp3,Akt3,Slc28a2,Notch1,Rac3,Chmp4b,Vps54,Acp5,Pdgfrb,Nod2,Csf1,Marcksl1,Homer1,Xrn1,Prdx5,Snx10,Ccne1,Pla2g4a,Smg7,Tlr9,Adrb2,Cd34,Gcnt2,Src,Fbxo4,Cacna1d,P2ry2,Lox,Smc5,Cx3cl1,Col11a2,Atm,Il6,Hif1a,Hspa1a,Kdr |
| 1.474e-03 | -6.52 | BIOCARTA_NO2IL12_PATHWAY | MSigDB lists | BIOCARTA_NO2IL12_PATHWAY | 17 | 6 | 15632 | 1249 |
Il12b,Nos2,Tyk2,Stat4,Il12rb1,Jak2 |
| 1.474e-03 | -6.52 | TERAMOTO_OPN_TARGETS_CLUSTER_7 | MSigDB lists | TERAMOTO_OPN_TARGETS_CLUSTER_7 | 17 | 6 | 15632 | 1249 |
Mthfd2,Ppp1r15a,H2-Ab1,Wars,Pde3b,Phgdh |
| 1.474e-03 | -6.52 | GO_L_ASCORBIC_ACID_BINDING | MSigDB lists | GO_L_ASCORBIC_ACID_BINDING | 17 | 6 | 15632 | 1249 |
P4ha2,Plod3,P4ha1,Phyh,Plod2,Egln3 |
| 1.474e-03 | -6.52 | LUND_SILENCED_BY_METHYLATION | MSigDB lists | LUND_SILENCED_BY_METHYLATION | 17 | 6 | 15632 | 1249 |
Odc1,H3f3b,Notch1,Sdc1,Hmox1,Sdc4 |
| 1.474e-03 | -6.52 | GO_REACTIVE_NITROGEN_SPECIES_METABOLIC_PROCESS | MSigDB lists | GO_REACTIVE_NITROGEN_SPECIES_METABOLIC_PROCESS | 17 | 6 | 15632 | 1249 |
Nqo1,Prdx5,Gch1,Nos2,Slc7a2,Arg2 |
| 1.474e-03 | -6.52 | GENTILE_UV_RESPONSE_CLUSTER_D1 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D1 | 17 | 6 | 15632 | 1249 |
Gem,Dusp1,Casp3,Ddit4,Rnd3,Stxbp3 |
| 1.474e-03 | -6.52 | MAHADEVAN_IMATINIB_RESISTANCE_UP | MSigDB lists | MAHADEVAN_IMATINIB_RESISTANCE_UP | 17 | 6 | 15632 | 1249 |
Cxcl14,Myo10,Pdgfc,Crim1,Bambi,Axl |
| 1.474e-03 | -6.52 | OUYANG_PROSTATE_CANCER_PROGRESSION_UP | MSigDB lists | OUYANG_PROSTATE_CANCER_PROGRESSION_UP | 17 | 6 | 15632 | 1249 |
Jun,Dusp16,Fos,Syk,Stat1,Stat3 |
| 1.474e-03 | -6.52 | MODULE_362 | MSigDB lists | MODULE_362 | 17 | 6 | 15632 | 1249 |
Il18,Jag1,Vegfc,Angpt1,Tnfaip2,Kdr |
| 1.474e-03 | -6.52 | GO_NEGATIVE_REGULATION_OF_LIPID_STORAGE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LIPID_STORAGE | 17 | 6 | 15632 | 1249 |
Tnf,Nfkbia,Itgav,Il6,Nr1h3,Ptpn2 |
| 1.474e-03 | -6.52 | PODAR_RESPONSE_TO_ADAPHOSTIN_DN | MSigDB lists | PODAR_RESPONSE_TO_ADAPHOSTIN_DN | 17 | 6 | 15632 | 1249 |
Sdc1,Hk2,Cxcl10,Cx3cr1,Idi1,Ccne1 |
| 1.479e-03 | -6.52 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate | KEGG pathways | M00001 | 26 | 8 | 7931 | 713 |
Eno2,Hk2,Hk1,Hk3,Pgk1,Tpi1,Pfkl,Eno1 |
| 1.479e-03 | -6.52 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate | KEGG pathways | mmu_M00001 | 26 | 8 | 7931 | 713 |
Hk2,Eno2,Eno1,Pgk1,Pfkl,Tpi1,Hk3,Hk1 |
| 1.487e-03 | -6.51 | regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032434 | 122 | 18 | 20694 | 1406 |
Hspa1b,Plk2,Mdm2,N4bp1,Rnf19a,Tlk2,Caml,Gclc,Trib3,Cop1,Rnf19b,Hspa1a,Rnf14,Plk3,Ankib1,Psmd10,Trib1,Dnajb2 |
| 1.491e-03 | -6.51 | GO_CYTOKINE_RECEPTOR_ACTIVITY | MSigDB lists | GO_CYTOKINE_RECEPTOR_ACTIVITY | 88 | 16 | 15632 | 1249 |
Il2rg,Il4ra,Il12b,Cd74,Il13ra1,Ebi3,Xcr1,Il15ra,Cmklr1,Csf3r,Ifnar1,Cx3cr1,Ccr1,Il12rb1,Ccrl2,Ccr3 |
| 1.498e-03 | -6.50 | GO_CELLULAR_RESPONSE_TO_ALCOHOL | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ALCOHOL | 113 | 19 | 15632 | 1249 |
Inhba,Errfi1,Fzd1,Ifnb1,Tnc,Il6,Prkce,Il10,Klf2,Ptch1,Klf6,Ccl5,Ass1,Ccl12,Il15,Pim1,Ptafr,Hmgcs1,Lrp8 |
| 1.499e-03 | -6.50 | GO_REGULATION_OF_GROWTH | MSigDB lists | GO_REGULATION_OF_GROWTH | 582 | 67 | 15632 | 1249 |
Ppp2r3a,Inhba,Sh3bp4,Osm,Hopx,Gja1,Dusp6,Dcbld2,Il12b,Gng4,Ptprj,Ptger4,Acvrl1,Cish,Stat3,Rab21,Serp1,Bcl6,Eno1,Stat5a,Tnf,Cd38,Crim1,Notch1,Sav1,Sgk3,Crlf3,Sphk1,Sertad3,Socs1,Hif1a,Pml,Hlx,Sirt1,Htra1,Slc9a1,Csf1,Ogfr,Ptch1,Sema3c,Il10,Irf8,Dcun1d3,S100a8,Cdkn1a,Socs7,H3f3b,Sema4a,Adrb2,Acvr1b,Socs3,C3,Sema4c,Ptk2,4932438A13Rik,Ifrd1,Mmp14,Psmd10,Agrn,Bcl2l11,Sqstm1,Ezr,Plac8,Pnpt1,Mul1,Cdk5r1,Cdkn2d |
| 1.500e-03 | -6.50 | HIF1_Q5 | MSigDB lists | HIF1_Q5 | 221 | 31 | 15632 | 1249 |
Psd,Phlpp1,Zfp800,Fchsd2,Tet2,Hmga1,Slc2a1,Cited2,Eno1,Bcl6,Gadd45b,Bcl2l11,Tle3,Tsku,Cdc42ep2,Bmp2,Hif1a,Lrp8,Pdgfb,Arl5b,Ubr4,Pdk3,Brwd3,P4ha1,Lhx2,Fam162a,Pim1,Ddx4,Max,Ptprj,Ldha |
| 1.508e-03 | -6.50 | Rho protein signal transduction | biological process | GO:0007266 | 75 | 13 | 20694 | 1406 |
Rhou,Pdpn,Rnd3,Rhof,Rhoq,Phactr4,Rac3,Rhoh,Rnd1,Rhoc,Cdc42ep2,Cdc42ep4,Bcl6 |
| 1.515e-03 | -6.49 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_UP | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_UP | 184 | 27 | 15632 | 1249 |
Mppe1,Phyh,Ms4a6d,Fndc3a,Oas1g,Rnaset2b,Osbpl3,Rnaset2a,Plekha2,Pdk3,Slc7a8,Oas1a,Cd180,Fabp3,H2-Q7,Hhex,Klf7,Ncoa7,Gbp2,Angpt1,Ciita,H2-Q6,Cd302,H2-Q4,Dhrs9,Abcc5,Ogfrl1 |
| 1.515e-03 | -6.49 | GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_UP | MSigDB lists | GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_UP | 184 | 27 | 15632 | 1249 |
Acp2,Htr2b,Rgs1,Gtpbp2,Slamf8,4930453N24Rik,Pde7b,Il12rb1,Stoml1,Tlr1,Irf7,Cnp,Cd86,Rnf31,Prpf38a,Enpp4,Tspo,Zbp1,Sphk1,Pttg1,Ddx58,Stxbp1,Stk40,Oas3,Lrp4,Parp8,P4ha2 |
| 1.515e-03 | -6.49 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | 184 | 27 | 15632 | 1249 |
Tank,Cyfip1,Fchsd2,Ankrd24,Hspa2,Optn,Nfkbie,Csrnp1,Tpx2,Prnp,Slc39a13,Hif1a,Dnase1l3,Mdfic,Sesn3,Myadm,Arid4a,Cd86,Oas2,Ptgir,Parp3,Casp7,Acsl1,Clic4,Irak2,Slc29a3,5430427O19Rik |
| 1.515e-03 | -6.49 | GSE27786_LIN_NEG_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_LIN_NEG_VS_ERYTHROBLAST_UP | 184 | 27 | 15632 | 1249 |
Ccdc86,Cept1,Mllt6,Fgl2,Nfkbie,Ythdf1,Nlrc5,Parp8,Syk,Sgcb,Mcmbp,Nck1,Rhoh,Slco3a1,Plscr1,Stat4,Tyk2,Mthfd1l,Tor3a,Lap3,Heatr6,Chd9,Epsti1,Casp7,Atp10a,Irf1,Lyn |
| 1.515e-03 | -6.49 | GSE2826_WT_VS_XID_BCELL_DN | MSigDB lists | GSE2826_WT_VS_XID_BCELL_DN | 184 | 27 | 15632 | 1249 |
Glipr2,Kdm5b,Cpd,Cish,Traf2,Spic,Axl,Map3k6,P4ha2,Plekha5,Ccl12,Clcn5,Chmp4b,Tle3,Pgm1,Slc30a1,Mapkapk2,Cdkn2d,Pla2g7,St3gal5,Gna15,Map2k1,Ptch1,Ptges,Vcam1,Nfkb2,Tgfbi |
| 1.519e-03 | -6.49 | IBR | pfam domains | PF01485 | 13 | 5 | 18711 | 1348 |
Rnf19a,Ankib1,Rnf19b,Rnf31,Rnf14 |
| 1.524e-03 | -6.49 | GO_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | 29 | 8 | 15632 | 1249 |
Il10,Cd274,Prnp,Axl,Tnfsf4,H2-Eb1,Zc3h12a,Inhba |
| 1.524e-03 | -6.49 | GO_NEGATIVE_REGULATION_OF_PROTEIN_MATURATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_MATURATION | 29 | 8 | 15632 | 1249 |
Birc2,Serpine1,Nlrc4,Ppp1r15a,Cd55,Birc3,Mdm2,Thbs1 |
| 1.524e-03 | -6.49 | SHIN_B_CELL_LYMPHOMA_CLUSTER_2 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_2 | 29 | 8 | 15632 | 1249 |
Fosb,Ccnd2,Dtx2,Gadd45b,Prdm1,Stat5a,Myc,Irf4 |
| 1.524e-03 | -6.49 | HOLLERN_SOLID_NODULAR_BREAST_TUMOR_DN | MSigDB lists | HOLLERN_SOLID_NODULAR_BREAST_TUMOR_DN | 29 | 8 | 15632 | 1249 |
Tpst1,Icam1,Gja1,Dgkh,P4ha2,Lrrc8c,Bmp2,Pdpn |
| 1.529e-03 | -6.48 | Signaling by Leptin | REACTOME pathways | R-MMU-2586551 | 11 | 5 | 8608 | 757 |
Stat5a,Jak2,Stat3,Socs3,Irs2 |
| 1.530e-03 | -6.48 | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN | MSigDB lists | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN | 148 | 23 | 15632 | 1249 |
Atxn7l1,Cnn3,Rasgrp1,B3gnt5,Snx2,Sesn3,Gypc,Fam43a,Slc25a37,Plekha2,Itpr1,Klf2,Rbm43,Pde3b,Dek,Zcchc2,Snn,Usp25,Cd55,Hhex,Rcsd1,Fam111a,Tmem229b |
| 1.532e-03 | -6.48 | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | 175 | 26 | 15632 | 1249 |
Timp1,Klf3,Gypc,Nfkbie,Bbx,Cdk5r1,Atf3,Ier2,Usp25,Hck,Irak3,Tsku,Cd83,Sla,Fzd5,Casp8,Casp2,Maff,H2-Ab1,St3gal1,Herc6,Il13ra1,Ell2,Orai2,Jak2,Ralgds |
| 1.532e-03 | -6.48 | AKT_UP.V1_DN | MSigDB lists | AKT_UP.V1_DN | 175 | 26 | 15632 | 1249 |
Zc3h12c,Klf2,Pde4b,Kctd12,Slc7a5,Htra1,Zeb1,Nr4a3,Il13ra1,Dram1,Asf1a,Fam20c,Ass1,Adhfe1,Stat5a,Gramd1a,Cnn2,C1ra,Slc39a4,Pla2g4a,Fut8,Irs2,Slco3a1,Slc39a13,Tulp3,Fas |
| 1.532e-03 | -6.48 | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | 175 | 26 | 15632 | 1249 |
Ms4a6d,Ttc39b,Abcc4,Prkx,Plat,Zc3h12c,Atm,Brwd3,Btg2,Sgms2,Ubash3b,Evl,Nfkbiz,Ncoa7,Tle3,Atp11b,Zc3hav1,Dnase1l3,Gclc,Cyfip1,Homer1,Arhgap26,Errfi1,I830077J02Rik,Pla2g4a,Tnc |
| 1.532e-03 | -6.48 | GSE3982_NEUTROPHIL_VS_BASOPHIL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_BASOPHIL_UP | 175 | 26 | 15632 | 1249 |
Slco3a1,Fgr,Ddx58,Prrg4,Atf3,Relb,Gbp2,Cdc42ep2,Htr2a,Pfkfb3,Bcl6,Rhbdf2,Acpp,Ehd1,P4ha2,Ppfia3,Treml2,Dusp2,Sema4a,Xkr8,Ptges,Cflar,Sipa1l1,Klf2,Il10,Phlda1 |
| 1.532e-03 | -6.48 | GSE7852_LN_VS_FAT_TCONV_UP | MSigDB lists | GSE7852_LN_VS_FAT_TCONV_UP | 175 | 26 | 15632 | 1249 |
Sesn3,Spsb1,Hmga1,Ptch1,Cenpj,Gpr18,Stard5,Bcl9,Inpp5b,Irgm2,Trim21,Cers6,Treml2,Cept1,Bcor,Stat1,Pikfyve,Dcp2,Usp18,Parp11,Acvr1b,Adar,Sgk3,Snn,Atp11b,Igf2bp2 |
| 1.532e-03 | -6.48 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_UP | 175 | 26 | 15632 | 1249 |
Lpar1,Nsmaf,Il2rg,C3,Itga5,Mob3c,Keap1,Cdkn1a,Abcc1,Tnip1,Hopx,Ccrl2,Kmo,Palld,Sdc4,Sav1,Dnaja1,Hsph1,Pik3r5,Il18bp,Mllt6,S1pr2,Gsr,Gadd45g,Gclm,Gpr35 |
| 1.539e-03 | -6.48 | Apoptosis - multiple species | KEGG pathways | mmu04215 | 32 | 9 | 7931 | 713 |
Casp7,Casp8,Pmaip1,Birc3,Apaf1,Birc2,Cycs,Casp3,Bcl2l11 |
| 1.539e-03 | -6.48 | Apoptosis - multiple species | KEGG pathways | ko04215 | 32 | 9 | 7931 | 713 |
Apaf1,Birc3,Pmaip1,Casp8,Casp7,Bcl2l11,Cycs,Casp3,Birc2 |
| 1.541e-03 | -6.48 | GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN | 157 | 24 | 15632 | 1249 |
Denr,Plat,Lrp11,Tnfsf10,Ppfibp2,Plek,Ptch1,Sco1,Pdss1,Rtn2,Fgr,Gpc1,Ehd1,Dpy19l1,Mgat1,Ttc39c,P2ry12,Gbp4,Gbp9,Mlkl,Sdc2,Fgl2,Mdm2,Vcan |
| 1.541e-03 | -6.48 | LEE_DIFFERENTIATING_T_LYMPHOCYTE | MSigDB lists | LEE_DIFFERENTIATING_T_LYMPHOCYTE | 166 | 25 | 15632 | 1249 |
Sla,Slfn5,Evl,Rhoh,Spata13,Sell,Ikzf1,Bcl2l11,Psmb9,Hcls1,Rnaset2b,Tagap,Sp110,Rcsd1,Ociad1,Btg2,Trim14,Rasgrp1,Dgka,Lnpep,Brd2,Itgal,Rnaset2a,Fubp1,Cep350 |
| 1.541e-03 | -6.48 | GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_UP | 166 | 25 | 15632 | 1249 |
Ccnd1,Slc44a1,Minpp1,Rgs14,Abcc5,Stat5a,Dpy19l1,Etv5,Mapkbp1,Lrp8,Ube2e1,Rtn2,Pstpip2,Slc13a3,Psat1,Atm,Trafd1,Armc8,Hsd17b7,Cflar,Il18,St7,Pik3cd,Mthfd2,Hmgcs1 |
| 1.543e-03 | -6.47 | liver development | biological process | GO:0001889 | 103 | 16 | 20694 | 1406 |
Hmox1,Ccnd1,Ahr,Sod2,Jun,Hlx,Notch2,Itpr1,Cited2,Hhex,Notch1,Tet2,Jarid2,Hp,Met,Rpgrip1l |
| 1.556e-03 | -6.47 | GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_IN_RESPONSE_TO_STRESS | MSigDB lists | GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_IN_RESPONSE_TO_STRESS | 57 | 12 | 15632 | 1249 |
Notch1,Hmox1,Egr1,Atf3,Nck1,Hif1a,Egln3,Cited2,Jun,Klf2,Rgs14,Ppp1r15a |
| 1.556e-03 | -6.47 | LEE_LIVER_CANCER_MYC_TGFA_UP | MSigDB lists | LEE_LIVER_CANCER_MYC_TGFA_UP | 57 | 12 | 15632 | 1249 |
Ccnd1,Plscr1,Tlr1,Slpi,Btg2,Lcn2,Ets2,Slc13a3,Plat,Mthfd2,Usp18,Icam1 |
| 1.556e-03 | -6.47 | GO_NUCLEOTIDE_PHOSPHORYLATION | MSigDB lists | GO_NUCLEOTIDE_PHOSPHORYLATION | 57 | 12 | 15632 | 1249 |
Pfkfb3,Pgk1,Cmpk2,Hk3,Pfkl,Tpi1,Ldha,Ak4,Hk2,Hk1,Eno2,Eno1 |
| 1.556e-03 | -6.47 | PID_SHP2_PATHWAY | MSigDB lists | PID_SHP2_PATHWAY | 57 | 12 | 15632 | 1249 |
Pdgfb,Il6,Sdc2,Map2k1,Pdgfrb,Lmo4,Jak2,Kdr,Igf1r,Angpt1,Stat1,Il2rg |
| 1.556e-03 | -6.47 | LEE_LIVER_CANCER_ACOX1_UP | MSigDB lists | LEE_LIVER_CANCER_ACOX1_UP | 57 | 12 | 15632 | 1249 |
Cd74,Ets2,Lcn2,Hdac1,Nqo1,Edn1,Col4a2,Plat,Slpi,H2-Aa,Plscr1,Slc16a1 |
| 1.556e-03 | -6.47 | PID_FAK_PATHWAY | MSigDB lists | PID_FAK_PATHWAY | 57 | 12 | 15632 | 1249 |
Nck1,Ptk2,Itga5,Klf8,Map2k4,Src,Itgav,Map2k1,Jun,Mmp14,Ccnd1,Arhgap26 |
| 1.568e-03 | -6.46 | GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | 122 | 20 | 15632 | 1249 |
Il1b,Hcls1,Bambi,Jak2,Sphk1,Il18,Tlr2,Il12b,Ptgs2,Ddx58,Lif,Zc3h12a,Tlr9,Tlr3,Csf3,Rbpms,Il6,Slc9a1,Tnfsf14,Tnf |
| 1.572e-03 | -6.46 | negative regulation of cell projection organization | biological process | GO:0031345 | 205 | 26 | 20694 | 1406 |
Lrp4,Lpar1,Mecp2,Katna1,Sema4a,Prnp,Evl,Sema3c,Cd38,Rapgef2,Plk2,Map4k4,Cdk5r1,Kremen1,Spry2,Sema4c,Stap1,Ifrd1,Rap1gap2,Prag1,Dync1i2,Ptk2,Gfi1,Rab3ip,Il15ra,Mdm2 |
| 1.588e-03 | -6.45 | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_BIOSYNTHETIC_PROCESS | 12 | 5 | 15632 | 1249 |
Il1b,Il1a,Cd86,Cd80,Irf4 |
| 1.588e-03 | -6.45 | GO_REGULATION_OF_MONOCYTE_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_MONOCYTE_DIFFERENTIATION | 12 | 5 | 15632 | 1249 |
Csf1,Myc,Gpr68,Jun,Irf7 |
| 1.588e-03 | -6.45 | PARK_TRETINOIN_RESPONSE | MSigDB lists | PARK_TRETINOIN_RESPONSE | 12 | 5 | 15632 | 1249 |
Plek,Smox,Sla,Pim1,Fgr |
| 1.588e-03 | -6.45 | GO_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | 12 | 5 | 15632 | 1249 |
Traf2,Casp8,Fas,Jak2,Tnfsf10 |
| 1.588e-03 | -6.45 | GO_MACROPHAGE_CHEMOTAXIS | MSigDB lists | GO_MACROPHAGE_CHEMOTAXIS | 12 | 5 | 15632 | 1249 |
Cx3cl1,Cx3cr1,Ccl12,Ednrb,Ccl5 |
| 1.588e-03 | -6.45 | GO_POSITIVE_REGULATION_OF_CELLULAR_EXTRAVASATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_EXTRAVASATION | 12 | 5 | 15632 | 1249 |
Ptafr,Icam1,Ccl12,Ptger4,Itga4 |
| 1.588e-03 | -6.45 | GO_ACTIVATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | 12 | 5 | 15632 | 1249 |
Pdgfc,Adrb2,Angpt1,Pilrb2,Pilrb1 |
| 1.588e-03 | -6.45 | GO_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS | 12 | 5 | 15632 | 1249 |
Il12b,Ebi3,Tlr3,Tlr9,Il27 |
| 1.588e-03 | -6.45 | GO_POSITIVE_REGULATION_OF_ASTROCYTE_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ASTROCYTE_DIFFERENTIATION | 12 | 5 | 15632 | 1249 |
Bmp2,Lif,Clcf1,Il1b,Notch1 |
| 1.588e-03 | -6.45 | GO_G_PROTEIN_COUPLED_PURINERGIC_NUCLEOTIDE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_G_PROTEIN_COUPLED_PURINERGIC_NUCLEOTIDE_RECEPTOR_SIGNALING_PATHWAY | 12 | 5 | 15632 | 1249 |
P2ry13,Ptafr,P2ry14,P2ry2,P2ry12 |
| 1.588e-03 | -6.45 | SCHAVOLT_TARGETS_OF_TP53_AND_TP63 | MSigDB lists | SCHAVOLT_TARGETS_OF_TP53_AND_TP63 | 12 | 5 | 15632 | 1249 |
Casp1,Fas,Cdkn1a,Mdm2,Vcan |
| 1.588e-03 | -6.45 | GO_RESPONSE_TO_COBALT_ION | MSigDB lists | GO_RESPONSE_TO_COBALT_ION | 12 | 5 | 15632 | 1249 |
Casp3,Fas,Bnip3,Casp8,Hif1a |
| 1.588e-03 | -6.45 | WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_DN | MSigDB lists | WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_DN | 12 | 5 | 15632 | 1249 |
Gbp3,Lcp2,Samsn1,Sla,Nlrc5 |
| 1.601e-03 | -6.44 | GO_RESPONSE_TO_INCREASED_OXYGEN_LEVELS | MSigDB lists | GO_RESPONSE_TO_INCREASED_OXYGEN_LEVELS | 23 | 7 | 15632 | 1249 |
Cdkn1a,Bnip3,Plau,Pdgfrb,Cav1,Fas,Nox1 |
| 1.601e-03 | -6.44 | GO_REGULATION_OF_MYELOID_CELL_APOPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_MYELOID_CELL_APOPTOTIC_PROCESS | 23 | 7 | 15632 | 1249 |
Clec5a,Irf7,Ccl5,Sirt1,Nod2,Hcar2,Kitl |
| 1.601e-03 | -6.44 | GO_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS | MSigDB lists | GO_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS | 23 | 7 | 15632 | 1249 |
H2-Eb1,Tnf,Kdm6b,Icam1,Rasgrp1,Il1b,Notch1 |
| 1.601e-03 | -6.44 | GO_POSITIVE_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION | 23 | 7 | 15632 | 1249 |
Fos,Gpr68,Il12b,Tnf,Csf1,Ccr1,Ccl5 |
| 1.602e-03 | -6.44 | regulation of cell-matrix adhesion | biological process | GO:0001952 | 113 | 17 | 20694 | 1406 |
Sdc4,Ptprj,Mmp14,Ptk2,Src,Plau,Acvrl1,Bcl6,Map4k4,Thbs1,Jag1,Plekha2,Csf1,Serpine1,Bst1,Kdr,Vegfc |
| 1.604e-03 | -6.44 | GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 368 | 46 | 15632 | 1249 |
Gclc,Usp25,Ctsc,Psmd10,Tiparp,Ezr,Rnf114,Dnajb2,Trib1,Odc1,Ptk2,Rnf19a,Psme2,Il10,Cav1,Nos2,Atm,Psmb8,Ankib1,Tnfrsf1b,Rnf14,Tnfaip3,Irak3,Psmb10,Plk3,Ube2e1,Psme1,Rnf139,Pml,Mdm2,Tlk2,Psma6,Psmb9,Timp1,Dusp1,Tnf,N4bp1,Il1b,Keap1,Trib3,Rnf19b,Smc5,Psmb6,Ppp2r3a,Plk2,Gja1 |
| 1.612e-03 | -6.43 | negative regulation of peptidyl-tyrosine phosphorylation | biological process | GO:0050732 | 58 | 11 | 20694 | 1406 |
Errfi1,Socs3,Mvp,Socs1,Cav1,Irf1,Il18,Samsn1,Ptpn2,Fam72a,Parp14 |
| 1.612e-03 | -6.43 | neuron death | biological process | GO:0070997 | 58 | 11 | 20694 | 1406 |
Casp3,Plau,Atm,Slc9a1,Bnip3,Apaf1,Usp53,Cxcl2,Casp7,Fas,Fam162a |
| 1.614e-03 | -6.43 | GSE22886_NAIVE_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_DC_DN | 194 | 28 | 15632 | 1249 |
Kctd12,Pla2g7,Slc7a8,Slc31a2,Adap2,Gca,Mtmr14,Mthfd2,Nr4a3,Slamf8,Igsf6,Kcnj2,Nqo1,Sdc2,Ap3b1,Txnrd1,Sqstm1,Syk,Rab32,Dock4,Dse,Slc48a1,Gclc,Prdx1,Plau,Crim1,Tpi1,Kmo |
| 1.614e-03 | -6.43 | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_DN | MSigDB lists | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_DN | 194 | 28 | 15632 | 1249 |
Itpr1,Psmb9,Timp1,Mgat1,Stat5a,Ifnar1,Il18bp,Fgl2,Fcgr2b,Stat3,Ctsc,Nkiras1,Mpp7,Mxd1,Tlr6,Sdc4,Tspo,Fcgr1,Mov10,Jarid2,Ednrb,Cnn3,Psme2,Grina,Tgfbi,Il13ra1,Slc31a1,Hmox1 |
| 1.620e-03 | -6.43 | LU_EZH2_TARGETS_UP | MSigDB lists | LU_EZH2_TARGETS_UP | 241 | 33 | 15632 | 1249 |
Oasl1,Dennd2a,Casp7,Ifi35,Ifit3b,Ier3,Trib3,Ppp2r2a,Pfkl,Psmb8,Ifit1bl2,Tor3a,Irf7,Ogfr,Ifit3,Ube2l6,Ddit4,G3bp2,Psmb10,Isg15,F11r,Ahsa1,Sdc4,Ppfibp1,Ppp1r14b,Sod2,Ifit1bl1,Rhof,Psmb9,Phgdh,Triobp,Hdac1,Tlk2 |
| 1.622e-03 | -6.42 | cellular transition metal ion homeostasis | biological process | GO:0046916 | 94 | 15 | 20694 | 1406 |
Lcn2,Slc39a14,Sco1,Cp,Slc30a1,Mt1,Myc,Slc39a13,Prnp,Hmox1,Slc31a2,Mt2,Slc31a1,Hif1a,Slc39a4 |
| 1.630e-03 | -6.42 | cell body | cellular component | GO:0044297 | 796 | 76 | 20747 | 1409 |
Rac3,Adora2a,Hdc,Prkar2b,Palld,Tlr2,Kdr,Cacna1d,Dync1h1,Plk3,P2ry12,Ass1,Htr2b,Hspa1b,Xrn1,Flnb,Ezr,Kcnj2,Txn1,Casp4,Cx3cl1,Fabp7,Acvrl1,Cacybp,Igf1r,Ptger4,Txnrd1,Tnfrsf1b,Eno2,Itpr1,Met,Fas,Pde1b,Cd200,Magohb,Tpx2,Sipa1l1,Lrp8,Ccl2,Adrb2,Lpar1,Cdk5r1,Map2k4,Stau1,Gnb4,Mul1,Cnn3,Katna1,Htr2a,Nqo1,Casp3,Ccr1,Tnf,Fcgr2b,Map2k1,Myo10,Pdgfb,Kif3c,Uchl1,Cyfip1,Slc31a1,Itga4,Daxx,Sdc2,Casp8,Lrp4,Rapgef2,Kremen1,Glrx,Cd40,Homer1,Hdac1,Kif5c,Gpc1,Optn,Cx3cr1 |
| 1.634e-03 | -6.42 | regulation of striated muscle cell differentiation | biological process | GO:0051153 | 123 | 18 | 20694 | 1406 |
Il4ra,Cflar,Ehd1,Daxx,Hopx,Tnfsf14,Cxcl9,Cxcl10,Edn1,Mmp14,Trip10,Notch1,Bmp2,Nr3c1,Gdf15,Ccl8,Tomm70a,Sirt1 |
| 1.636e-03 | -6.42 | regulation of muscle system process | biological process | GO:0090257 | 238 | 29 | 20694 | 1406 |
Trip10,Ptk2,Agrn,Notch1,Pde5a,Tomm70a,Pde4b,Tnfrsf1b,Zc3h12a,Sirt1,Calcrl,Cav1,Dock4,Nr4a3,Sphk1,Edn1,Errfi1,Adora2b,Kcnj2,Jarid2,Map2k1,Slc9a1,Adrb2,Nr3c1,Ptgs2,Ptger4,Atp2b4,Ptafr,Arg2 |
| 1.638e-03 | -6.41 | LABBE_TGFB1_TARGETS_DN | MSigDB lists | LABBE_TGFB1_TARGETS_DN | 97 | 17 | 15632 | 1249 |
Tap1,Plaur,Gclc,Kitl,Pbx1,Myd88,Tmem176b,Mmp13,Cp,Plscr1,Ccl2,Casp3,Kcnj2,Pstpip2,Lcn2,Cav1,Gdf15 |
| 1.643e-03 | -6.41 | GSE22886_NAIVE_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_MEMORY_TCELL_DN | 185 | 27 | 15632 | 1249 |
Hivep2,Timp1,Cited2,Acvr1,Gsr,Ift57,Ube2e1,Ccnd2,Tab2,Mdfic,Rbl1,Ahr,Eif4g2,4930523C07Rik,Birc3,Samsn1,Rasgrp1,Casp2,Tmod3,Dnaja2,Ldha,Aida,Dek,Tnfsf10,Bambi,Tmem123,Pkp4 |
| 1.643e-03 | -6.41 | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_UP | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_UP | 185 | 27 | 15632 | 1249 |
Abtb2,Psat1,Gna15,Lcn2,Ascc3,Timeless,Pdlim7,G3bp2,Rnf19a,Xaf1,Slc31a1,Itga5,Chic2,Osgin2,Trib1,Gpd2,Frmd4a,Dpy19l1,Mrpl52,Dock4,D1Ertd622e,Ppp2r5a,Ubtd2,Rab9,Cdkn2d,Rnf139,Arrdc4 |
| 1.643e-03 | -6.41 | GSE27786_CD4_TCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_MONO_MAC_DN | 185 | 27 | 15632 | 1249 |
Rnf24,Carhsp1,Batf2,Gpr35,Casp3,Axl,Gpc1,Sgk3,Rbl1,Nck1,Sass6,Mpp7,Irs2,Agtrap,Arg2,Sap30,Vasp,Cxcl2,Myadm,Snx10,Txn1,Osm,Glrx,Cdkn1a,Cpeb4,Rab20,Slc43a3 |
| 1.643e-03 | -6.41 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP | 185 | 27 | 15632 | 1249 |
Trafd1,Clcn7,Kif3c,Grina,Socs3,Srxn1,Irf7,Klf2,Brwd3,Pde4b,Jarid2,Tnfaip3,Cd14,Slco3a1,Irs2,Usp18,Trim13,Nqo1,Pde1b,Slc39a4,Jun,Fos,Abcc5,Plekha5,Agrn,Slc7a11,Stat5a |
| 1.643e-03 | -6.41 | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP | 185 | 27 | 15632 | 1249 |
Slfn9,Nfkb2,Slc29a3,Acsl5,Cdkn1a,Lhx2,St3gal1,Hmgcs1,Asb13,Psme2,Uba7,Pou2f2,Ubr4,Rel,Traf5,Bfar,Rgs3,Apaf1,Xrn1,Gbp3,Usp18,Plagl1,Myc,Tnfsf8,Slfn8,Tapbp,Gypc |
| 1.643e-03 | -6.41 | GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_DN | MSigDB lists | GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_DN | 185 | 27 | 15632 | 1249 |
Ass1,Nr4a1,Cnn2,Rhoq,Ly75,Irgm2,Cx3cl1,Irs2,Sdc1,Mthfr,Col18a1,Evl,Cd83,Rnaset2a,Pdk3,Psat1,Stx6,G3bp2,Snx2,Trim21,Lpar1,Rnf145,Dck,Etnk1,Crkl,Pkp4,Rnaset2b |
| 1.644e-03 | -6.41 | positive regulation of calcium ion transport | biological process | GO:0051928 | 133 | 19 | 20694 | 1406 |
Homer1,Itpr1,Cxcl10,Ccl4,Pdgfb,Hspa2,Cx3cl1,Ccl5,Serpine1,Cav1,Cacna1d,Tspo,Pdgfrb,Adrb2,Cacnb3,Slc9a1,Ccl12,Ccr1,Hap1 |
| 1.644e-03 | -6.41 | antigen processing and presentation of peptide antigen via MHC class Ib | biological process | GO:0002428 | 34 | 8 | 20694 | 1406 |
H2-T24,H2-T10,H2-M2,H2-T22,H2-Q6,H2-Q7,Tap2,H2-Q4 |
| 1.644e-03 | -6.41 | regulation of purine nucleotide biosynthetic process | biological process | GO:1900371 | 34 | 8 | 20694 | 1406 |
Myc,Ak4,Stat3,Adora2b,Pid1,Pdk3,Nos2,Map2k1 |
| 1.644e-03 | -6.41 | cellular oxidant detoxification | biological process | GO:0098869 | 34 | 8 | 20694 | 1406 |
Selenow,Prdx1,Prdx5,Nqo1,Srxn1,Hp,Sod2,S100a8 |
| 1.644e-03 | -6.41 | positive regulation of T cell migration | biological process | GO:2000406 | 34 | 8 | 20694 | 1406 |
Tnfsf4,Ccl5,Cxcl10,Tnfsf14,Spn,Lgals9,Tnfrsf14,Itga4 |
| 1.644e-03 | -6.41 | peptidyl-tyrosine autophosphorylation | biological process | GO:0038083 | 34 | 8 | 20694 | 1406 |
Src,Hck,Sla,Kdr,Igf1r,Ptk2,Lyn,Fgr |
| 1.644e-03 | -6.41 | regulation of mast cell degranulation | biological process | GO:0043304 | 34 | 8 | 20694 | 1406 |
Hmox1,Rabgef1,Il4ra,Lyn,Adora2b,Stxbp1,Syk,Fgr |
| 1.644e-03 | -6.41 | regulation of nucleotide biosynthetic process | biological process | GO:0030808 | 34 | 8 | 20694 | 1406 |
Adora2b,Pid1,Nos2,Pdk3,Map2k1,Myc,Ak4,Stat3 |
| 1.647e-03 | -6.41 | T cell migration | biological process | GO:0072678 | 20 | 6 | 20694 | 1406 |
Itga4,Crkl,Cxcl10,Ccl5,Icam1,Ccl2 |
| 1.647e-03 | -6.41 | negative regulation of T-helper cell differentiation | biological process | GO:0045623 | 20 | 6 | 20694 | 1406 |
Il4ra,Hlx,Tnfsf4,Bcl6,Irf1,Zc3h12a |
| 1.647e-03 | -6.41 | mitotic G1/S transition checkpoint | biological process | GO:0044819 | 20 | 6 | 20694 | 1406 |
Plk3,Ccnd1,Cdkn1a,Pml,Casp2,Mdm2 |
| 1.647e-03 | -6.41 | myeloid dendritic cell differentiation | biological process | GO:0043011 | 20 | 6 | 20694 | 1406 |
Batf,Tnfsf9,Irf4,Batf2,Relb,Notch2 |
| 1.647e-03 | -6.41 | amyloid-beta clearance | biological process | GO:0097242 | 20 | 6 | 20694 | 1406 |
Igf1r,Msr1,Marco,Lrp4,C3,Ldlr |
| 1.647e-03 | -6.41 | negative regulation of smooth muscle contraction | biological process | GO:0045986 | 20 | 6 | 20694 | 1406 |
Ptgs2,Dock4,Calcrl,Adora2b,Adrb2,Ptger4 |
| 1.655e-03 | -6.40 | GSE6259_DEC205_POS_DC_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_DEC205_POS_DC_VS_CD8_TCELL_DN | 140 | 22 | 15632 | 1249 |
Glipr2,Irf4,Slc39a4,Prkce,Zyx,Cx3cr1,Cd80,Ccnd2,Nek6,Pml,Syne2,Ppp2r3a,Tmeff1,Zc3h12c,Daam1,Mov10,Pik3r6,Jarid2,Gcnt2,Ier3,Mefv,Pim2 |
| 1.655e-03 | -6.40 | GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA | MSigDB lists | GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA | 140 | 22 | 15632 | 1249 |
Fut8,Pdgfb,Edn1,Acvr1,Acvrl1,Src,Cx3cr1,Gdf15,Ccl5,Ltbp2,Ccl12,Fos,Cav1,Zyx,Jun,Col4a2,Gcnt2,Bambi,Apaf1,Ptk2,Pml,F11r |
| 1.656e-03 | -6.40 | KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION | MSigDB lists | KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION | 65 | 13 | 15632 | 1249 |
Met,Casp3,Atp6v1d,Jun,Ccl5,Nfkb1,Ikbkg,Src,Nfkbia,Nod1,Map2k4,Lyn,F11r |
| 1.656e-03 | -6.40 | GO_POSITIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS | 65 | 13 | 15632 | 1249 |
Kat2b,Hif1a,Ptafr,Irs2,Ptger4,Dyrk2,Il15,Htr2a,Ptpn2,Src,Nfkb1,Pdgfb,Prkce |
| 1.656e-03 | -6.40 | GO_PHAGOCYTIC_VESICLE_MEMBRANE | MSigDB lists | GO_PHAGOCYTIC_VESICLE_MEMBRANE | 65 | 13 | 15632 | 1249 |
Rab20,Tlr2,H2-Q7,Tlr6,H2-Q6,H2-Q4,Rab32,Rab10,Irgm2,Inpp5b,Rab9,Rab11fip1,Tlr1 |
| 1.656e-03 | -6.40 | PID_LYSOPHOSPHOLIPID_PATHWAY | MSigDB lists | PID_LYSOPHOSPHOLIPID_PATHWAY | 65 | 13 | 15632 | 1249 |
Jun,Gna15,Fos,Nfkb1,Src,Nfkbia,Il6,Prkce,Casp3,Lyn,Lpar1,Mmp9,Ptk2 |
| 1.656e-03 | -6.40 | REACTOME_ER_PHAGOSOME_PATHWAY | MSigDB lists | REACTOME_ER_PHAGOSOME_PATHWAY | 65 | 13 | 15632 | 1249 |
Tap1,Psmb10,Psmb6,Psme1,H2-Q7,Psma6,Psme2,Tap2,Psmb9,Psmd10,H2-Q6,H2-Q4,Psmb8 |
| 1.658e-03 | -6.40 | GO_NEGATIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | 50 | 11 | 15632 | 1249 |
Bmp2,Cflar,Daxx,Notch1,Cxcl10,Il18,Pdgfb,Cxcl14,Hdac1,Tnf,Ankrd17 |
| 1.658e-03 | -6.40 | DELASERNA_MYOD_TARGETS_DN | MSigDB lists | DELASERNA_MYOD_TARGETS_DN | 50 | 11 | 15632 | 1249 |
Gbp2,Cd34,Tgfbi,Mpp7,Serpinb9,Sdc2,Rbpms,Vasn,Fzd1,Klf6,Pde4b |
| 1.665e-03 | -6.40 | GSE28408_LY6G_POS_VS_NEG_DC_DN | MSigDB lists | GSE28408_LY6G_POS_VS_NEG_DC_DN | 176 | 26 | 15632 | 1249 |
Ggct,Rab9,Psma6,Tapbp,Cebpd,Cx3cr1,Sp140,Il15,Tnfrsf8,Cd38,Egr1,Cd74,Trim12c,Ccrl2,Eno2,Snx10,Tnfrsf1b,Pdgfrb,Acsl5,Dek,Ldlr,Idi1,Ifi35,Uchl1,Irf1,Arid5b |
| 1.665e-03 | -6.40 | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 176 | 26 | 15632 | 1249 |
Insl6,Birc2,Sat1,Phgdh,Parp9,Il15,Cd38,Igsf9,Tor3a,Gja1,Rnf14,Plekha2,G3bp2,Stat4,Egln3,Mtmr14,Osgin2,Rcsd1,Serpinb9,Gtpbp2,Dek,Cldnd1,Pfkl,Acp2,Glrx,Vrk2 |
| 1.665e-03 | -6.40 | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_DN | MSigDB lists | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_DN | 176 | 26 | 15632 | 1249 |
Gypc,Sod2,B4galt4,Sat1,Cyth3,Usp18,Isg15,Bmp2,Gclc,Cd80,Ripk3,Samhd1,Slc4a7,Tor3a,Itgal,Ext1,Akt3,Phlpp2,Tyk2,Kpna3,Il13ra1,Rtn1,Itga9,Cxcl10,Ralgds,Ap3m2 |
| 1.673e-03 | -6.39 | Apoptotic factor-mediated response | REACTOME pathways | R-MMU-111471 | 7 | 4 | 8608 | 757 |
Casp3,Casp7,Apaf1,Cycs |
| 1.675e-03 | -6.39 | GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_DN | MSigDB lists | GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_DN | 149 | 23 | 15632 | 1249 |
Egr3,Nfkbiz,Ube2e1,Lif,Pim2,Adora2b,Map3k8,Mapkbp1,Clcf1,Lipg,Rab3ip,Tnf,Dusp1,Fos,Irf8,Klf2,Trip10,Ets2,Ext1,Rab21,Arl5b,Dusp2,Dusp4 |
| 1.678e-03 | -6.39 | GO_G_PROTEIN_COUPLED_RECEPTOR_BINDING | MSigDB lists | GO_G_PROTEIN_COUPLED_RECEPTOR_BINDING | 232 | 32 | 15632 | 1249 |
Ccl12,Homer1,Hspa1a,Dnaja1,Edn1,Stat3,Ccl2,S1pr2,Cxcl14,Ccl22,Rtp4,Znrf3,Cx3cl1,Ccl3,Ednrb,Ccl5,Gna15,Ccrl2,Rapgef2,Cxcl2,Tyk2,Fzd1,Uchl1,C3,Adrb2,Cxcl10,Cxcl1,Rpgrip1l,Jak2,Bambi,Ccl4,Pf4 |
| 1.678e-03 | -6.39 | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_UP | MSigDB lists | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_UP | 167 | 25 | 15632 | 1249 |
Arhgap26,Tnfsf8,Mdn1,Fcgr2b,Pik3r5,Ppp1r14b,Cx3cr1,Klf3,Traf5,Pigv,Sell,Fas,Lrch3,Itga4,Il18rap,Rap1gap2,Dgka,Smpdl3b,Tlr1,Ikbke,Rcsd1,Il18,St3gal1,Cd55,Arl5c |
| 1.678e-03 | -6.39 | GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_DN | MSigDB lists | GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_DN | 167 | 25 | 15632 | 1249 |
Lcn2,Gna15,Ccne1,Myadm,Mthfd1l,S100a8,Bst1,Ppp4r2,Slpi,Acsl1,Trib1,Ldha,Mmp9,Pcgf5,Hp,Fam53c,Ldlr,Bambi,Arf4,Il1rn,Bcl6,Rbpms,Gpr84,Sat1,Hlx |
| 1.681e-03 | -6.39 | HAN_JNK_SINGALING_DN | MSigDB lists | HAN_JNK_SINGALING_DN | 36 | 9 | 15632 | 1249 |
Cd74,Sema3c,Lcn2,Fas,Socs3,C3,Ahr,Cd14,Cp |
| 1.681e-03 | -6.39 | GO_B_CELL_PROLIFERATION | MSigDB lists | GO_B_CELL_PROLIFERATION | 36 | 9 | 15632 | 1249 |
Ifna5,Ifnb1,Ifna2,Plcl2,Ifna1,Ifna6,Il10,Cd180,Cd40 |
| 1.681e-03 | -6.39 | GO_REGULATION_OF_MAST_CELL_ACTIVATION | MSigDB lists | GO_REGULATION_OF_MAST_CELL_ACTIVATION | 36 | 9 | 15632 | 1249 |
Plscr1,Rabgef1,Hmox1,Syk,Adora2b,Il4ra,Lyn,Nr4a3,Fgr |
| 1.681e-03 | -6.39 | GO_POLYUBIQUITIN_BINDING | MSigDB lists | GO_POLYUBIQUITIN_BINDING | 36 | 9 | 15632 | 1249 |
Sqstm1,Ikbkg,Parp10,Tnip3,Tab2,Ikbke,Tnfaip3,Dnajb2,Optn |
| 1.681e-03 | -6.39 | TRAF6 mediated NF-kB activation | REACTOME pathways | R-MMU-933542 | 16 | 6 | 8608 | 757 |
Ikbkg,Nfkbia,Nfkb2,Myd88,Nfkb1,Nfkbib |
| 1.681e-03 | -6.39 | Nucleotide-like (purinergic) receptors | REACTOME pathways | R-MMU-418038 | 16 | 6 | 8608 | 757 |
Adora2a,P2ry2,P2ry13,P2ry14,P2ry12,Adora2b |
| 1.682e-03 | -6.39 | GSE3720_LPS_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_DN | MSigDB lists | GSE3720_LPS_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_DN | 158 | 24 | 15632 | 1249 |
Psmb8,Asah2,Cnp,Nfkbib,Psme2,Gpr132,Fzd1,Traf3ip2,Filip1l,Cd55,Nr4a3,Ikbke,Wdr43,Fam162a,Pik3r5,Tnfsf8,Stap1,Myc,Ccr3,Prrg4,Psme1,Evl,Sell,Chmp4b |
| 1.701e-03 | -6.38 | Tyr_kinase_cat_dom | interpro domains | IPR020635 | 81 | 14 | 19984 | 1430 |
Kdr,Flt1,Syk,Tyk2,Src,Pdgfrb,Met,Axl,Hck,Igf1r,Fgr,Lyn,Ptk2,Jak2 |
| 1.704e-03 | -6.37 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | 73 | 14 | 15632 | 1249 |
Psme2,Psma6,Psmb8,H2-Q4,Lnpep,Itgav,H2-Q6,Psmb9,Psmd10,Fcgr1,H2-Q7,Psme1,Psmb6,Psmb10 |
| 1.704e-03 | -6.37 | REACTOME_PLATELET_HOMEOSTASIS | MSigDB lists | REACTOME_PLATELET_HOMEOSTASIS | 73 | 14 | 15632 | 1249 |
Pde5a,Pla2g4a,Pde1b,Ppp2r5a,Nos2,Gng12,Gnb4,Gng11,Ppp2r1b,Pde3b,Fgr,Ptgir,Lrp8,Gng4 |
| 1.704e-03 | -6.37 | KEGG_CHRONIC_MYELOID_LEUKEMIA | MSigDB lists | KEGG_CHRONIC_MYELOID_LEUKEMIA | 73 | 14 | 15632 | 1249 |
Cdkn1a,Pik3cd,Crkl,Ccnd1,Mdm2,Hdac1,Myc,Akt3,Map2k1,Ikbkg,Nfkb1,Pik3r5,Nfkbia,Stat5a |
| 1.708e-03 | -6.37 | regulation of purine nucleotide metabolic process | biological process | GO:1900542 | 76 | 13 | 20694 | 1406 |
Ak4,Hif1a,Nupr1,Nos2,Myc,Htr2a,Ier3,Stat3,Pid1,Adora2b,Ddit4,Pdk3,Map2k1 |
| 1.711e-03 | -6.37 | GO_ENDOTHELIAL_CELL_DEVELOPMENT | MSigDB lists | GO_ENDOTHELIAL_CELL_DEVELOPMENT | 43 | 10 | 15632 | 1249 |
Clic4,Rap2c,Met,Rapgef2,Col18a1,Plod3,Myadm,Ezr,F11r,Icam1 |
| 1.711e-03 | -6.37 | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN | MSigDB lists | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN | 43 | 10 | 15632 | 1249 |
Kat2b,Egr1,Ier2,Klf6,Igf1r,Pdlim7,Ext1,Vcam1,Csf1,Col4a2 |
| 1.711e-03 | -6.37 | GO_POSITIVE_REGULATION_OF_CELL_KILLING | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_KILLING | 43 | 10 | 15632 | 1249 |
H2-Q7,H2-Q4,Ccl12,Bcl2l11,H2-Q6,Il12b,Nos2,Stap1,Il12rb1,Rasgrp1 |
| 1.711e-03 | -6.37 | GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_ABSENCE_OF_LIGAND | MSigDB lists | GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_ABSENCE_OF_LIGAND | 43 | 10 | 15632 | 1249 |
Cx3cr1,Tnf,Fas,Hspa1a,Cx3cl1,Il1a,Ppp2r1b,Il1b,Pf4,Inhba |
| 1.711e-03 | -6.37 | GO_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY | 81 | 15 | 15632 | 1249 |
Nod2,Prdx5,Edn1,Cav1,Tnf,Nfkb1,Gch1,Ripk3,Atp2b4,Gfi1,Htr2b,Il1b,Nod1,Hif1a,Hp |
| 1.713e-03 | -6.37 | establishment or maintenance of actin cytoskeleton polarity | biological process | GO:0030950 | 14 | 5 | 20694 | 1406 |
Rictor,Rnd1,Rnd3,Rhoc,Rhof |
| 1.713e-03 | -6.37 | negative regulation of macrophage activation | biological process | GO:0043031 | 14 | 5 | 20694 | 1406 |
Nr1h3,Cx3cl1,Ldlr,Cd200,Cst7 |
| 1.713e-03 | -6.37 | signal transduction involved in mitotic DNA integrity checkpoint | biological process | GO:1902403 | 14 | 5 | 20694 | 1406 |
Atm,Mdm2,Cdkn1a,Casp2,Pml |
| 1.713e-03 | -6.37 | signal transduction involved in mitotic cell cycle checkpoint | biological process | GO:0072413 | 14 | 5 | 20694 | 1406 |
Casp2,Pml,Mdm2,Cdkn1a,Atm |
| 1.713e-03 | -6.37 | negative regulation of type 2 immune response | biological process | GO:0002829 | 14 | 5 | 20694 | 1406 |
Hlx,Bcl6,Ifnb1,Irf1,Arg2 |
| 1.713e-03 | -6.37 | response to granulocyte macrophage colony-stimulating factor | biological process | GO:0097012 | 14 | 5 | 20694 | 1406 |
Etv3,Jak2,Zfp36,Pde1b,Stat5a |
| 1.713e-03 | -6.37 | regulation of MHC class II biosynthetic process | biological process | GO:0045346 | 14 | 5 | 20694 | 1406 |
Jak2,Sirt1,Ciita,Il10,Pf4 |
| 1.713e-03 | -6.37 | signal transduction involved in mitotic DNA damage checkpoint | biological process | GO:1902402 | 14 | 5 | 20694 | 1406 |
Mdm2,Cdkn1a,Atm,Pml,Casp2 |
| 1.713e-03 | -6.37 | positive regulation of DNA damage response, signal transduction by p53 class mediator | biological process | GO:0043517 | 14 | 5 | 20694 | 1406 |
Spred3,Atm,Spred1,Pmaip1,Eef1e1 |
| 1.713e-03 | -6.37 | negative regulation of monooxygenase activity | biological process | GO:0032769 | 14 | 5 | 20694 | 1406 |
Cav1,Atp2b4,Nfkb1,Gfi1,Arg2 |
| 1.713e-03 | -6.37 | antigen processing and presentation of exogenous peptide antigen via MHC class II | biological process | GO:0019886 | 14 | 5 | 20694 | 1406 |
Fcgr2b,H2-Eb1,H2-Ab1,Cd74,H2-Aa |
| 1.718e-03 | -6.37 | regulation of insulin secretion | biological process | GO:0050796 | 185 | 24 | 20694 | 1406 |
Prkce,Hmgn3,Nos2,Tnf,Ccl5,Irs2,Slc16a1,Cacna1d,Klf7,Hif1a,Jak2,Gja1,Pfkl,Pde3b,Nlgn2,Glrx,Pim3,Il1b,Sirt1,Serp1,Map4k4,Hdac1,Gpr68,Cd38 |
| 1.729e-03 | -6.36 | Dual-sp_phosphatase_cat-dom | interpro domains | IPR000340 | 40 | 9 | 19984 | 1430 |
Dusp8,Dusp2,Dusp1,Dusp6,Dusp14,Dusp5,Dusp28,Dusp4,Dusp16 |
| 1.734e-03 | -6.36 | regulation of peptide hormone secretion | biological process | GO:0090276 | 228 | 28 | 20694 | 1406 |
Pfkl,Nlgn2,Gja1,Jak2,Irs2,Klf7,Slc16a1,Clcf1,Hmgn3,Prkce,Ccl5,Sirt1,Pim3,Hmga2,Il1b,Pde3b,Lif,Ptger4,Hif1a,Cacna1d,Tnf,Nos2,Hdac1,Cd38,Gpr68,Map4k4,Serp1,Glrx |
| 1.736e-03 | -6.36 | regulation of phosphatidylinositol 3-kinase activity | biological process | GO:0043551 | 42 | 9 | 20694 | 1406 |
Fpr2,Lyn,Nod2,Pik3r5,Fgr,Pdgfb,Pdgfrb,Flt1,Src |
| 1.736e-03 | -6.36 | positive regulation of phospholipase activity | biological process | GO:0010518 | 42 | 9 | 20694 | 1406 |
Ccl5,Sele,Lpar1,Ptafr,Pdgfrb,Htr2b,Flt1,Arf4,Htr2a |
| 1.736e-03 | -6.36 | negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | biological process | GO:0002823 | 42 | 9 | 20694 | 1406 |
Parp3,Ifnb1,Nod2,Il4ra,Fcgr2b,Tnfsf4,Bcl6,Spn,Zc3h12a |
| 1.742e-03 | -6.35 | hydrolase activity, acting on ester bonds | molecular function | GO:0016788 | 734 | 72 | 20217 | 1400 |
Acp2,Dusp6,Rbbp8,Endod1,Eya4,Zc3h12a,Pde7b,Mppe1,Cnp,Isg20,Pnpt1,Dusp8,Smpdl3b,Prkar2b,Ubash3b,Pfkfb3,Acpp,Pde4b,Ptpn2,Dusp1,Pla2g7,Pla2g4a,Phlpp2,Nod2,Ppm1l,Dusp2,Helz2,Pde3b,Acp5,Dusp28,Inpp5b,Phlpp1,Esd,Lipg,Plpp3,Ppm1k,Usb1,Zc3h12c,Ppp2r2a,Slfn9,Pde5a,Rnaset2a,Inpp1,Dusp4,Dusp14,Rnaset2b,Plaat3,Dcp2,Lipe,Noct,Nt5c3,Ccl5,Ddhd1,Xrn1,Dnase1l3,Pde1b,Samhd1,Ppp2r1b,Aoah,Ago3,Mtmr14,Ppp2r5a,Slfn8,Minpp1,Ptprj,Rcl1,Plpp1,Ccr1,Hmox1,Dusp5,Plcl2,Dusp16 |
| 1.745e-03 | -6.35 | EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP | MSigDB lists | EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP | 195 | 28 | 15632 | 1249 |
Lif,Parp3,H2-Q7,Nox1,Cx3cl1,Acsl1,Isg15,Fabp3,Cxcl10,Calcrl,Tnfaip2,Cdc42ep2,Traf5,Myo10,Agrn,Tagln,Spn,H2-Q4,Klf6,Ezr,Plek,Gadd45b,H2-Q6,Pdlim7,Irgq,C1ra,Egln3,Hivep3 |
| 1.745e-03 | -6.35 | phosphatidylinositol 3-kinase complex | cellular component | GO:0005942 | 27 | 7 | 20747 | 1409 |
Socs3,Pik3cd,Socs1,Cish,Socs7,Pik3r6,Pik3r5 |
| 1.749e-03 | -6.35 | negative regulation of alpha-beta T cell differentiation | biological process | GO:0046639 | 27 | 7 | 20694 | 1406 |
Bcl6,Irf1,Zc3h12a,Il4ra,Hlx,Tnfsf4,Socs1 |
| 1.749e-03 | -6.35 | negative regulation of oxidoreductase activity | biological process | GO:0051354 | 27 | 7 | 20694 | 1406 |
Atp2b4,Arg2,Prdx5,Gfi1,Nfkb1,Hp,Cav1 |
| 1.749e-03 | -6.35 | mast cell activation | biological process | GO:0045576 | 27 | 7 | 20694 | 1406 |
Lcp2,Milr1,Nr4a3,Fcgr2b,Rasgrp1,Rhoh,Lyn |
| 1.754e-03 | -6.35 | enzyme inhibitor activity | molecular function | GO:0004857 | 379 | 42 | 20217 | 1400 |
Birc3,Slpi,Cd55,Kat2b,Cst7,Serpina3f,Notch1,C3,Serpinb2,Nck1,Wars,Atp2b4,Prkar2b,Ppp1r12b,Parp9,Trib1,Serpina3g,Serpine1,Wfdc17,Dtx3l,Birc2,Socs1,Serpinb9,Bcl2a1d,Cdkn1a,Cdkn2d,Trib3,Crim1,Tnfsf14,Ctla2b,Serpinb9b,Spint2,Serpinb6b,Timp1,Rhoh,Casp3,Spred1,Ppp1r14b,Prdx5,Agrn,Phactr4,Pttg1 |
| 1.774e-03 | -6.33 | developmental process involved in reproduction | biological process | GO:0003006 | 736 | 71 | 20694 | 1406 |
Src,Bcl2l11,Cdyl,Tut7,Casp4,Map2k1,Marf1,Casp2,Htra1,Hif1a,Pdgfb,Lif,Atm,Serpinb6b,Nos2,Ptgs2,Sirt1,Tiparp,Notch1,Hmga2,Il1b,Diaph2,Axl,Spint2,Gja1,Itgav,Tdrd7,Crkl,Ahr,Pbx1,Ccnd1,Zmynd15,Inhba,Met,Angpt1,Prdm1,H3f3b,Taf4b,Acvr1,Etv5,Plaur,Pla2g4a,Il10,Dach1,Tnc,Arid4a,Socs3,Kdr,Stxbp1,Cited2,Il1a,Stat5a,Kitl,Junb,Fzd5,Insl6,Arid5b,Itga4,Nectin2,Kdm5b,Birc2,Vcam1,Trip13,Fndc3a,Igf1r,Hspa2,Icam1,Csf1,Nupr1,Notch2,Serpine1 |
| 1.778e-03 | -6.33 | GO_PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY | MSigDB lists | GO_PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY | 330 | 42 | 15632 | 1249 |
Pde7b,Smpdl3b,Eya4,Phlpp2,Inpp5b,Map2k1,Ppm1k,Cnp,Ccl5,Ppp1r15b,Dusp6,Pde4b,Ccr1,Acp2,Dusp28,Ppp2r2a,Dusp16,Inpp1,Plcl2,Mppe1,Hmox1,Dusp5,Ptprj,Mtmr14,Pde5a,Dusp4,Phlpp1,Pde1b,Dusp8,Dusp2,Minpp1,Cycs,Ptpn2,Acpp,Dusp1,Samhd1,Dusp14,Pde3b,Pfkfb3,Ppm1l,Pikfyve,Ubash3b |
| 1.779e-03 | -6.33 | GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_DN | MSigDB lists | GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_DN | 186 | 27 | 15632 | 1249 |
Pttg1,Mdfic,Daxx,Tmem184b,Eno1,Cyfip1,Ifnar1,Mlkl,Lztfl1,Nod2,Mdm2,Optn,Dennd1b,Slfn8,Pim1,Cox18,Cacnb3,Oas1g,Nfil3,Dusp16,Pkp4,Slfn9,Cldnd1,Nfxl1,Arf4,Irf7,Oas1a |
| 1.779e-03 | -6.33 | GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_DN | 186 | 27 | 15632 | 1249 |
Slpi,Slamf9,Mmd,Gja1,Irf8,Myo1b,Vegfc,Pfkl,Mmp9,C3,Pim2,Tgfbi,Grina,Clec4d,Slc39a4,C1ra,Nqo1,Spn,Cx3cr1,Serp1,Tspo,Gclc,Tal2,Olfml3,Cdkn2d,Lif,Tulp3 |
| 1.779e-03 | -6.33 | GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_DN | 186 | 27 | 15632 | 1249 |
Ap3m2,Frmd6,Igf2bp2,Slfn9,Tnip1,Znrf1,Slfn3,Arid5b,Acvr1b,Smox,Inpp5b,Slfn4,Gbp2,Zc3hav1,Hvcn1,Rras2,Trp53i11,Sell,Ddx58,Cdkn2d,Fas,Treml2,Rffl,Slfn8,Rhof,Psip1,Gramd1a |
| 1.779e-03 | -6.33 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_INF_UP | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_INF_UP | 186 | 27 | 15632 | 1249 |
Gpr68,Fcgr2b,Ctsc,Swap70,Zyx,Samhd1,Pilrb2,Slamf7,Gpc1,P2ry14,Slco3a1,Prrg4,AA467197,Btg2,Samsn1,Plek,Ccl5,Cdkn1a,Nfil3,Pilrb1,Prkx,Rcn1,Ier3,Dgkh,Ptprj,Dusp5,Ptgir |
| 1.779e-03 | -6.33 | GSE8621_LPS_STIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE8621_LPS_STIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN | 186 | 27 | 15632 | 1249 |
1600014C10Rik,Lpcat2,Smg7,Gbe1,Dock10,B3gnt5,Mllt6,Nfkbie,Ikzf1,Pik3r5,Parp8,Frmd6,Snn,Epsti1,Cd82,Rcsd1,Fam111a,Kctd12,Ppp4r2,Timeless,Nmi,Wdfy1,Reps1,Sap30,Cd86,Irf8,Samsn1 |
| 1.779e-03 | -6.33 | GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN | MSigDB lists | GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN | 186 | 27 | 15632 | 1249 |
Glrx,Cdkn1a,St7,Traf3ip2,Ptk2,Usp12,Tmeff1,Itgal,Rnf14,Eno2,Jarid2,Hck,Aff1,1600014C10Rik,Sgcb,Sdc4,Nxf1,Pttg1,Nkiras1,Tlr6,Mcoln2,Fas,Slc44a1,Mmp14,Plod3,Cenpe,Nfkbia |
| 1.779e-03 | -6.33 | GSE15330_WT_VS_IKAROS_KO_LYMPHOID_MULTIPOTENT_PROGENITOR_UP | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_LYMPHOID_MULTIPOTENT_PROGENITOR_UP | 186 | 27 | 15632 | 1249 |
Cd86,Mov10,Irf7,Jarid2,Atm,Stat4,Csf1,Chic2,Ptger4,Ppp2r2a,Ap3m2,Glrx,Hcls1,Gypc,Rnf114,Fgl2,Hspa2,Parp14,Sat1,Slc44a1,Ly75,Slco3a1,Nr1h3,Rtp4,Usp25,Tnfrsf14,Rbm43 |
| 1.779e-03 | -6.33 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DN | 186 | 27 | 15632 | 1249 |
Dusp6,Tor3a,Hdc,Casp4,Tnfsf14,Plscr1,Sap30,Rnf19a,Atp10a,Rnf19b,Bcl2a1a,Dusp28,Casp1,Plekha5,Pik3r5,Bcl2a1b,Trim36,Batf2,Pde5a,Bcl2a1d,Mcoln2,Cdk5r1,Slco3a1,St3gal6,Slamf7,Pde3b,Olr1 |
| 1.780e-03 | -6.33 | modification of morphology or physiology of other organism | biological process | GO:0035821 | 144 | 20 | 20694 | 1406 |
Ccl4,Slpi,Tlr2,Ccl5,Serpinb9,Irgm2,Tnip1,Jun,Pcx,Trem1,Bcl2l11,Ccl2,Mmp9,Rab9,Zc3h12a,Irgm1,Gsdmd,Pf4,Hdac1,Myc |
| 1.785e-03 | -6.33 | RUIZ_TNC_TARGETS_DN | MSigDB lists | RUIZ_TNC_TARGETS_DN | 132 | 21 | 15632 | 1249 |
Mcm10,Odc1,Mcm6,Fam111a,Plau,Rras2,Serpinb2,Thbs1,Dio2,Crim1,Olr1,Ccne1,Cav1,Pnp2,Trip13,Slc7a5,Ccdc86,Pdss1,Ogfrl1,Sh3bp4,Met |
| 1.785e-03 | -6.33 | GO_MAINTENANCE_OF_LOCATION | MSigDB lists | GO_MAINTENANCE_OF_LOCATION | 132 | 21 | 15632 | 1249 |
Nfkbib,Flnb,Syne2,Hk2,Nfkbie,G3bp2,Hk1,S100a8,Nfkbia,Tnf,Ezr,Morc3,Gpsm2,Il10,Psmd10,Cav1,Tspo,Il1b,Keap1,Pml,Nfkbil1 |
| 1.789e-03 | -6.33 | SYNDECAN | prosite domains | PS00964 | 4 | 3 | 13278 | 1037 |
Sdc1,Sdc4,Sdc2 |
| 1.793e-03 | -6.32 | transition metal ion homeostasis | biological process | GO:0055076 | 124 | 18 | 20694 | 1406 |
Myc,Slc39a13,Mt1,Slc30a1,Prnp,Lcn2,Cp,Sco1,Slc39a14,Slc31a1,Slc30a4,Cutc,Slc39a4,Hif1a,Sod2,Mt2,Hmox1,Slc31a2 |
| 1.793e-03 | -6.32 | regulation of cellular ketone metabolic process | biological process | GO:0010565 | 124 | 18 | 20694 | 1406 |
Atp2b4,Prkce,Nr4a3,Egr1,Ptgs2,Slc7a11,Irs2,Cav1,Sirt1,Gk,Nr1h3,Pdk3,Bmp2,Il1b,Pla2g4a,Acsl5,Fabp3,Trib3 |
| 1.794e-03 | -6.32 | BENPORATH_NANOG_TARGETS | MSigDB lists | BENPORATH_NANOG_TARGETS | 886 | 95 | 15632 | 1249 |
Sdc4,Kif9,Extl2,Tle3,Klf7,Spred1,Ifi207,Tpx2,Papss2,Ifi214,Ap3b1,Vcan,Cept1,Cnn2,Cited2,Ptpn2,Trip10,Ppp2r1b,Arf4,Vrk2,Dtx2,Pim2,Mmp9,Ifi204,Ifi211,Cnn3,Egln3,Mndal,Sema3c,Mov10,Cav1,Pbx1,Sgk3,Sav1,Prpf38a,Olfml3,Zfp281,F11r,Rnf24,Tnc,Phgdh,Stat3,Glipr2,Rbpms,Txnrd1,Serp1,Ifi209,Sec24a,Cdc42ep4,Arid5b,Ppp2r3a,Dusp6,Gja1,Hsd17b12,Cdyl,Rrs1,Adar,Ppfibp1,Angpt1,Prnp,Pdpn,Slc44a1,Taf4b,Slc7a11,Jun,Fam20c,Tmem123,Kdr,Ell2,Kpna3,Etnk1,Bcl9,Ifi203,Eef1e1,Rnf31,P4ha1,Eif4g2,Bmp2,Ahsa1,Hhex,Pnp2,Gypc,Clmp,Parp8,Ifi213,Ifi205,Bambi,Clic4,Gng12,Mob3b,Ak4,Slc7a5,Ifi208,Wars,Jarid2 |
| 1.804e-03 | -6.32 | cytoskeleton organization | biological process | GO:0007010 | 1026 | 94 | 20694 | 1406 |
Mark2,Ccdc88b,Rnd1,Fscn1,Bcl6,Pdlim7,Actb,Slc16a1,Daam1,Dync1h1,Fignl2,Phip,Brwd3,Zyx,Ccl12,Katna1,Pstpip2,Nck1,Gpr35,Arhgap26,Trim36,Tuba4a,Plk3,Tnf,Tpx2,Sik3,Gpsm2,Cnn3,Diaph2,Csrp1,Palld,Cav1,Spire1,Tagln,Dbnl,Rhof,F11r,Dnaaf3,Tpm4,Cep350,Plk2,Plek,Whamm,Cflar,Abr,Syne2,Vasp,Cnn2,Ptk2,Nectin2,Rac3,Rhoc,Vps54,Pdgfrb,Spry2,Carmil1,Tmsb10,Frmd6,S1pr2,Antxr1,Rhoq,Triobp,Sipa1l1,Cnp,Ezr,Evl,Fmnl2,Ccl2,Rhou,Phactr4,Mecp2,Cenpj,Cenpe,Trip10,Rgs14,Rhoh,Swap70,Rictor,Sbds,Tnfaip3,Rnd3,Flnb,Znrf1,Micall2,Hcls1,Sass6,Casp4,Cdc42ep2,Src,Myo1b,Tmod3,Pdgfb,Dst,Marcks |
| 1.807e-03 | -6.32 | GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP | 177 | 26 | 15632 | 1249 |
Gca,Fmnl2,Igf1r,Agpat4,Frmd6,Cd200,Kif5c,Gpr85,Frmd4a,Ttc9c,Rel,Vezt,Layn,Gnb4,Rab3ip,Cd38,Gda,Cyth3,Phip,Ppm1l,Gbp3,Egr2,Ifi44,Cpd,Parp8,Swap70 |
| 1.807e-03 | -6.32 | GSE16450_CTRL_VS_IFNA_12H_STIM_MATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_CTRL_VS_IFNA_12H_STIM_MATURE_NEURON_CELL_LINE_DN | 177 | 26 | 15632 | 1249 |
Pla2g7,Tmem176a,Cxcl2,Btg2,Tlr1,Psme2,Samsn1,Socs7,Trafd1,Abcc1,Il1rn,Dnajb4,Chic2,Acvr1b,Slamf8,Tapbpl,Kpna3,Slc15a3,Spryd7,Cst7,Tap1,Cd14,Ddx58,Nmral1,Sass6,Tmem176b |
| 1.807e-03 | -6.32 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN | 177 | 26 | 15632 | 1249 |
Ptprj,Itga5,Rtn1,Il13ra1,Tgfbi,Rcsd1,Fam111a,Clec4d,Cxcl10,Xcr1,Clec4n,Myadm,Cd180,Nlrp3,Clec4e,Slamf7,Gclc,Pdgfc,Me1,Dhrs9,Msr1,Acpp,Zyx,Cited2,Slc44a1,Fgl2 |
| 1.807e-03 | -6.32 | GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_UP | MSigDB lists | GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_UP | 177 | 26 | 15632 | 1249 |
Atp11b,Rras2,Il4ra,Calcrl,Psd,Vcan,Mecp2,Rnf24,Ppp2r5a,Bbx,Nr3c1,Pik3r5,Ifit2,Bambi,Ust,Fam102b,Cflar,Tmod3,Ptk2,Ptger4,Usp12,Trim56,Ampd3,Cnn3,Col11a2,Card6 |
| 1.807e-03 | -6.32 | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_DN | 177 | 26 | 15632 | 1249 |
Samhd1,Ciita,Tab2,Ccnd2,P2ry14,Evl,Irf4,Ccdc86,Rhof,Hmga1,Slc2a1,Cnn2,Axl,Hivep2,Cst7,Fam162a,Acsl5,Asf1a,Il2rg,Il18,Ppa1,Dyrk2,Mmd,Sh3bp4,Spint2,Zeb1 |
| 1.810e-03 | -6.31 | DSPc | pfam domains | PF00782 | 40 | 9 | 18711 | 1348 |
Dusp16,Dusp8,Dusp28,Dusp6,Dusp4,Dusp1,Dusp14,Dusp5,Dusp2 |
| 1.817e-03 | -6.31 | purinergic nucleotide receptor activity | molecular function | GO:0001614 | 20 | 6 | 20217 | 1400 |
Hcar2,P2ry2,Ptafr,P2ry12,P2ry13,P2ry14 |
| 1.817e-03 | -6.31 | nucleotide receptor activity | molecular function | GO:0016502 | 20 | 6 | 20217 | 1400 |
P2ry2,Hcar2,Ptafr,P2ry13,P2ry14,P2ry12 |
| 1.822e-03 | -6.31 | REACTOME_GLUCOSE_METABOLISM | MSigDB lists | REACTOME_GLUCOSE_METABOLISM | 58 | 12 | 15632 | 1249 |
Tpi1,Eno2,Gbe1,Eno1,Pgm1,Gys1,Ppp2r1b,Pfkfb3,Pcx,Pgk1,Pfkl,Slc25a12 |
| 1.826e-03 | -6.31 | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D | 789 | 86 | 15632 | 1249 |
Snn,Abcc4,Ppp2r2a,Sec24b,Il15ra,Slc37a3,Inpp1,Elmod2,Arid5b,Chic2,Traf3ip2,Parp3,Hmox1,Kdm6b,Tbc1d13,Dgka,G3bp2,Sipa1l1,Serpine1,Rnaset2a,Ppm1k,Hsd17b12,Snx10,Ripk3,Bfar,Myd88,Mapkbp1,Rab19,Slc39a13,Lif,Mxd1,Stk40,Ccng2,Mlkl,Mdm2,Cish,Rab9,Tank,Cd302,Bcl6,Traf2,Mtus1,Klhl25,Plod3,Plekhf2,Usp53,Lipe,Stat5a,Cdkn1a,Armc8,Pfkl,Rnaset2b,Tnfaip2,Tnip1,Whamm,Rbms1,Arf4,Sema4a,Stat1,Mtdh,Eef1e1,Hivep3,Mmd,Ksr1,Casp8,Lnpep,Ppp1r15b,Rbm43,Slc48a1,Slc25a25,Pim3,Nr1h3,Mpp7,Etv3,Prnp,Kat2b,Nek6,Nfkbiz,Pcx,Ifrd1,Cept1,4932438A13Rik,Aftph,Igsf6,Tiparp,Adhfe1 |
| 1.826e-03 | -6.31 | GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_UP | 168 | 25 | 15632 | 1249 |
Rap1gap2,Sirt1,Wdfy1,Tuba4a,Bambi,Idi1,Acsl1,Mob3b,Acvr1b,Traf3ip2,Itga5,Ell2,Mtmr14,Il18bp,Slc2a1,Rhof,Bcl6,Gypc,Mul1,Pttg1,Mapkapk2,Bcor,Plk3,Malt1,Hhex |
| 1.826e-03 | -6.31 | GSE25087_TREG_VS_TCONV_FETUS_UP | MSigDB lists | GSE25087_TREG_VS_TCONV_FETUS_UP | 168 | 25 | 15632 | 1249 |
Samsn1,Cacybp,Itgal,Snx10,Mmd,Srxn1,Ksr1,Map3k8,Gpd2,Tnip3,Pim1,Trib1,Frmd6,Cldnd1,Adam19,Lrp4,B3gnt5,Ly75,Cish,Rab11fip1,Irs2,Tab2,Kat2b,Ube2e1,Ahr |
| 1.826e-03 | -6.31 | GSE21033_CTRL_VS_POLYIC_STIM_DC_1H_DN | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_1H_DN | 168 | 25 | 15632 | 1249 |
Scarf1,Zyx,Sqstm1,Pfkfb3,Socs1,Mapkapk2,Dcp1a,Nfkbib,Phlpp2,Akt3,Vps54,Rel,Ltbp2,Nfkb1,Junb,Gsta3,H3f3b,Nfkb2,Acsl5,Rbms1,Azi2,Il18,Acvr1b,Dyrk2,Kdm6b |
| 1.826e-03 | -6.31 | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_UP | MSigDB lists | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_UP | 168 | 25 | 15632 | 1249 |
Prnp,Ccl22,Icam1,Sla,Plagl2,Ezr,Srm,Irf4,Tgs1,Ccnd1,Ppa1,Tnip3,Rcan1,Acsl1,Clcn7,Arf4,Cd82,Rgs1,Nfil3,Junb,Btg2,Nfkbib,Zfp324,Inhba,Maff |
| 1.826e-03 | -6.31 | GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | 168 | 25 | 15632 | 1249 |
Klf8,Ciita,Sla,Slc48a1,Gbp2,Ppfibp1,Hck,Lipe,Nr4a1,Tpst1,Il6,Kdm5b,Tapbp,Cers6,Dtnb,Herc6,St3gal1,Xkr8,Kcna3,Siglece,Gpr132,Zfp36,Zfp324,Uba7,Rap1gap2 |
| 1.835e-03 | -6.30 | SNF5_DN.V1_UP | MSigDB lists | SNF5_DN.V1_UP | 159 | 24 | 15632 | 1249 |
Rbl1,Fcgr1,Evl,C1ra,Tapbp,Mmp14,Egr2,Znfx1,Psmb9,Ass1,Ifit2,Cx3cr1,Ifit1bl1,Lhx2,Cxcl10,Oasl1,Hat1,Fabp7,Inpp5b,Isg20,Tap2,Plek,Psmb8,Ifit1bl2 |
| 1.838e-03 | -6.30 | GO_TRANSITION_METAL_ION_HOMEOSTASIS | MSigDB lists | GO_TRANSITION_METAL_ION_HOMEOSTASIS | 98 | 17 | 15632 | 1249 |
Slc39a14,Cp,Slc39a4,Myc,Sco1,Lcn2,Slc31a2,Slc25a37,S100a8,Cutc,Hif1a,Slc39a13,Prnp,Slc30a1,Slc30a4,Hmox1,Slc31a1 |
| 1.839e-03 | -6.30 | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN | 205 | 29 | 15632 | 1249 |
Plagl2,Gys1,Gclc,Gbe1,Spata13,Gpr35,Bnip3,Slc2a1,Jun,Homer1,Ass1,P4ha2,Dusp1,Ehd1,Il15ra,Fam162a,Gcnt2,Vcam1,Hmox1,Pdlim7,Srxn1,Isg20,Plekha2,Nos2,Serpine1,Higd1a,Tnfrsf1b,Jarid2,Eno2 |
| 1.842e-03 | -6.30 | PILON_KLF1_TARGETS_UP | MSigDB lists | PILON_KLF1_TARGETS_UP | 462 | 55 | 15632 | 1249 |
Fzd5,Daam1,Nrp2,Fzd1,Hmox1,St3gal1,Vcam1,Il1b,Dcbld2,H2-Q6,Dusp8,Mdm2,Ogfrl1,H2-Q7,Itga4,Lipg,Pbx1,Bfar,Rhoc,Clcn5,Ednrb,Marco,Med13,Srxn1,Ell2,Hmgcs1,Cpeb4,Etnk1,Mthfd2,Dnajb4,Rbms1,Actb,Dnajb2,Wdr43,Prkar2b,Igf1r,Agrn,Flt1,H2-Q4,Msr1,Aftph,Slc44a1,Gclm,Bnip3,Sdc2,Col18a1,Rars,Irs2,Cx3cl1,Nr1h3,Slc30a1,Ciapin1,Plagl1,Gng11,Me1 |
| 1.856e-03 | -6.29 | mitogen-activated protein kinase binding | molecular function | GO:0051019 | 34 | 8 | 20217 | 1400 |
Gch1,Dusp2,Tnip1,Dusp1,Sirt1,Ptprj,Mapkapk2,Ptafr |
| 1.865e-03 | -6.28 | platelet-derived growth factor receptor binding | molecular function | GO:0005161 | 14 | 5 | 20217 | 1400 |
Pdgfb,Lyn,Ptprj,Pdgfrb,Pdgfc |
| 1.876e-03 | -6.28 | GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 640 | 72 | 15632 | 1249 |
Cdkn1a,Asf1a,Polr2g,Lyn,Ifi204,Dyrk2,Casp2,Ifi203,Egln3,Sirt1,Ube2e2,Timeless,Trip13,Ifi211,Mndal,Cenpj,Mcm9,Tnfrsf1b,Ikbkg,Atm,Tnks1bp1,Ifi207,Hinfp,Ifi214,Pttg1,Plagl1,Nek6,Mapkapk2,Cdkn2d,Parp9,Cnot4,Myc,Hmga1,Dnaja1,Bcl2l11,Bcl2a1b,Tcea1,Ikbke,Bcl2a1a,Parp3,Smc5,Hmox1,Uba7,Eya4,Ifi208,Ube2l6,Ddit4,Btg2,Ascc3,Irf7,Plk2,Ppp1r15a,Ube2f,Batf,Isg15,Dtx3l,Pml,Nupr1,Plk3,Mcm10,Bcl2a1d,Ccnd1,Mdm2,Tlk2,Top3a,Casp3,Ifi205,Rbbp8,Ifi209,Bcl6,Ifi213,Tnf |
| 1.885e-03 | -6.27 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | 196 | 28 | 15632 | 1249 |
Ifi203,Hivep3,Ifi208,Timeless,Trip13,Ifi211,Mndal,Txn1,Tcea1,Chd9,Rpgrip1l,Mcm6,Ifi204,Denr,Psma6,Ifi209,Ptpn2,Ifi205,Ets2,Txnrd1,Psip1,Cenpe,Ifi213,Rab32,Ifi207,Gng11,Rras2,Ifi214 |
| 1.885e-03 | -6.27 | GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN | MSigDB lists | GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN | 196 | 28 | 15632 | 1249 |
Rras2,Pim3,Plk3,Palld,Hif1a,Prnp,Abcb1a,Nr3c1,Tor1aip2,Ctsc,Pde1b,Pcx,Dusp1,Gpsm2,Plat,Plaur,Rnf19b,Denr,Ppa1,Srxn1,Tmeff1,Mmp13,Inhba,Egln3,Tdrd7,Slc4a7,Col11a2,Serpine1 |
| 1.885e-03 | -6.27 | GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_UP | MSigDB lists | GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_UP | 196 | 28 | 15632 | 1249 |
Ehd1,H2-Q4,Eno2,Snx10,Phldb1,H2-Q6,Cd40,Csf3r,Sat1,Pdlim7,Psme2,Nat2,Ap3b1,Il12rb1,Hk2,H2-Q7,Dtx2,Ccl22,Usp18,Psmb10,Il15,Polr2g,Cd82,Plat,Ikbke,Cd80,Dusp16,Glrx |
| 1.885e-03 | -6.27 | regulation of glucose transmembrane transport | biological process | GO:0010827 | 86 | 14 | 20694 | 1406 |
Il1b,Pid1,Trib3,C3,Rtn2,Met,Myc,Tnf,Nr4a3,Irs2,Edn1,Stxbp3,Rhoq,Hk2 |
| 1.899e-03 | -6.27 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | 577 | 66 | 15632 | 1249 |
AA467197,Arl5b,Ifi208,Sipa1l1,Cacybp,Asns,Nampt,Slc4a7,Mthfd1l,Glrx,Plaur,Clic4,Snapc1,Osbpl3,Mcm6,Spire1,Ak4,Gsr,Pnp2,Cycs,Phgdh,Ifi205,Gpsm2,Slc2a1,Tank,Rbbp8,Ifi209,Eno1,Plod3,Ifi213,P4ha2,Dpy19l1,Mcmbp,Upp1,Ifi203,Hat1,Slc39a14,Zeb1,Ifi211,Zc3h7a,Mndal,Lnpep,P4ha1,Ccne1,Eif4g2,Psat1,Eno2,Gfpt1,Mthfd2,Gpd2,Ifi204,Nqo1,Rai14,Ggct,Ctsc,Ppp1r14b,Slc7a11,Rbl1,Ifi207,Slc16a1,Gpc1,Pnpt1,Sgcb,Ifi214,Sass6,Rars |
| 1.902e-03 | -6.26 | MODULE_128 | MSigDB lists | MODULE_128 | 90 | 16 | 15632 | 1249 |
Cebpd,Kctd12,Pdgfrb,Timp1,Ccl5,Ccl12,Ccr1,Gbp2,Cd14,Fcgr1,Thbs1,Vcam1,Fpr1,Ier3,Ccnd2,Mmp9 |
| 1.911e-03 | -6.26 | WANG_SMARCE1_TARGETS_UP | MSigDB lists | WANG_SMARCE1_TARGETS_UP | 253 | 34 | 15632 | 1249 |
Sipa1l1,Ifit3,Jdp2,Dach1,Etv6,Fzd1,Jag1,Wars,Antxr1,Ifit3b,Map3k8,Tgfbi,Il13ra1,Cd200,Rtn1,Socs3,Cd55,Dio2,Plat,Rbms1,Pcdh7,Tagln,Flrt3,Ifit2,Vcan,Glipr2,Sdc2,Itgb8,Slc44a1,Nupr1,Me1,Tle3,Klf7,Lpcat2 |
| 1.915e-03 | -6.26 | GO_G1_DNA_DAMAGE_CHECKPOINT | MSigDB lists | GO_G1_DNA_DAMAGE_CHECKPOINT | 66 | 13 | 15632 | 1249 |
Plk2,Cenpj,Atm,Mdm2,Ccnd1,Cnot4,Casp2,Btg2,Plagl1,Plk3,Pml,Cdkn1a,Tnks1bp1 |
| 1.915e-03 | -6.26 | GO_B_CELL_MEDIATED_IMMUNITY | MSigDB lists | GO_B_CELL_MEDIATED_IMMUNITY | 66 | 13 | 15632 | 1249 |
H2-Ab1,Cd55,Fas,C3,Cd74,Il4ra,Batf,H2-Eb1,Swap70,C1rl,Irf7,C1ra,Pou2f2 |
| 1.918e-03 | -6.26 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | MSigDB lists | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | 124 | 20 | 15632 | 1249 |
H3f3b,Prkar2b,Ifna2,Jak2,Ifna1,Kif9,Irf1,Mafg,Kif3c,Irf2,Hdac1,Mafk,Maff,Dock10,Ifna5,Ifnb1,Ifna6,Dock4,Irf7,Ehd1 |
| 1.918e-03 | -6.26 | Signaling by EGFR | REACTOME pathways | R-MMU-177929 | 312 | 43 | 8608 | 757 |
Angpt1,Rictor,Psme2b,Src,Irs2,Ppp2r5a,Phlpp2,Spred1,Kitl,Cdkn1a,Pdgfb,Ppp2r1b,Cd86,Spry2,Jak2,Nr4a1,Map2k1,Ksr1,Il2rg,Pdgfrb,Prkce,Psmd10,Phlpp1,Psme2,Cd80,Psma6,Trib3,Psmb10,Met,Mdm2,Ptk2,Psmb8,Ier3,Prkar2b,Psme1,Dusp5,Psmb6,Dusp6,Rapgef2,Pik3cd,Pde1b,Rasgrp1,Psmb9 |
| 1.924e-03 | -6.25 | AAGCACT_MIR520F | MSigDB lists | AAGCACT_MIR520F | 215 | 30 | 15632 | 1249 |
Itga9,Usp42,Nr4a3,Pcgf5,Fndc3a,Dnaja2,Ralgds,Asf1a,Cep350,Arid4a,Rgl1,Ednrb,Hivep3,Rictor,Ppp2r3a,Ccnd2,Abr,Irf2,Spred1,Rbl1,Znfx1,Mtus1,Tiparp,Flt1,Ddhd1,Ccnd1,Mecp2,Aebp2,Zfp800,Cpd |
| 1.925e-03 | -6.25 | regulation of actin polymerization or depolymerization | biological process | GO:0008064 | 176 | 23 | 20694 | 1406 |
Rac3,Hcls1,Evl,Nck1,Cdc42ep4,Cdc42ep2,Csf3,Plek,Whamm,Swap70,Rictor,Fchsd2,Vasp,Tmsb10,Carmil1,Spire1,Tlr2,Prkce,Tmod3,Icam1,Myadm,Cyfip1,Dbnl |
| 1.925e-03 | -6.25 | GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP | 187 | 27 | 15632 | 1249 |
Pou2f2,Ddit4,Phlda1,Plk2,Tnfsf14,Serpine1,Map2k1,Ifit1bl2,Slc7a8,Acp2,Tcea1,Abcc1,Htr2b,Ikbke,Odc1,Ptgir,Hmox1,Dtx2,Nqo1,Ifit1bl1,Sqstm1,Slc16a3,Tle3,Cd180,St3gal6,Marcksl1,Abr |
| 1.925e-03 | -6.25 | GSE27786_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_NKCELL_DN | 187 | 27 | 15632 | 1249 |
Phyh,Grina,Map3k8,Oasl1,Rtn1,Osbpl3,Nfxl1,Tor1aip1,Rel,Gem,Snx10,Jarid2,Itga4,Tmem176b,Nfkbiz,Mapkapk2,Pbx1,Tet2,Csf3r,Fam43a,Abcc5,Lrp4,Rin2,Mlkl,Spry2,Casp3,Ppp2r5a |
| 1.925e-03 | -6.25 | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_UP | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_UP | 187 | 27 | 15632 | 1249 |
Inpp1,Frmd4a,Dram1,Dyrk2,Mmd,Stx11,Htra1,Hopx,Snx10,Rhoc,Pde3b,Atp11a,Calcrl,Arrdc4,Slco3a1,H2-Q7,Magohb,Gsr,Gpr68,Ankrd24,Cish,H2-Q6,Klhl25,Ifit2,Rab32,H2-Q4,Nlrc5 |
| 1.925e-03 | -6.25 | GSE14308_INDUCED_VS_NATURAL_TREG_DN | MSigDB lists | GSE14308_INDUCED_VS_NATURAL_TREG_DN | 187 | 27 | 15632 | 1249 |
Klf7,Nxf1,Trim12c,Arrdc4,Il4ra,Ppm1l,Mcoln2,Psme1,Ap3b1,Acpp,Trmt1l,Hivep2,Morc3,Cmpk2,Prkx,Tax1bp1,Plcl2,Clcn7,Snapc1,Elmod2,Rnf145,Smc5,Mmd,Cysltr2,Zc3h7a,Golga3,Asah2 |
| 1.930e-03 | -6.25 | regulation of nucleotide metabolic process | biological process | GO:0006140 | 77 | 13 | 20694 | 1406 |
Stat3,Ier3,Htr2a,Myc,Map2k1,Pdk3,Ddit4,Adora2b,Pid1,Hif1a,Ak4,Nos2,Nupr1 |
| 1.935e-03 | -6.25 | WILENSKY_RESPONSE_TO_DARAPLADIB | MSigDB lists | WILENSKY_RESPONSE_TO_DARAPLADIB | 30 | 8 | 15632 | 1249 |
Plaur,Pla2g7,Ccl5,Hmox1,Mmp9,Ccr1,Ptafr,Il1a |
| 1.935e-03 | -6.25 | REACTOME_CD28_CO_STIMULATION | MSigDB lists | REACTOME_CD28_CO_STIMULATION | 30 | 8 | 15632 | 1249 |
Akt3,Cd80,Rictor,Src,Cd86,Trib3,Map3k8,Lyn |
| 1.935e-03 | -6.25 | PID_P38_ALPHA_BETA_PATHWAY | MSigDB lists | PID_P38_ALPHA_BETA_PATHWAY | 30 | 8 | 15632 | 1249 |
Fgr,Map2k4,Lyn,Dusp1,Src,Hck,Dusp16,Dusp8 |
| 1.935e-03 | -6.25 | MODULE_265 | MSigDB lists | MODULE_265 | 30 | 8 | 15632 | 1249 |
Myd88,Tlr1,Il15ra,Il13ra1,Il4ra,Csf3r,Il2rg,Tlr2 |
| 1.935e-03 | -6.25 | GO_RESPONSE_TO_MINERALOCORTICOID | MSigDB lists | GO_RESPONSE_TO_MINERALOCORTICOID | 30 | 8 | 15632 | 1249 |
Cdkn1a,Fosb,Ccnd1,Fos,Ccne1,Junb,Edn1,Src |
| 1.935e-03 | -6.25 | PID_AVB3_OPN_PATHWAY | MSigDB lists | PID_AVB3_OPN_PATHWAY | 30 | 8 | 15632 | 1249 |
Jun,Fos,Itgav,Mmp9,Nfkb1,Syk,Plau,Nfkbia |
| 1.935e-03 | -6.25 | HU_GENOTOXIC_DAMAGE_24HR | MSigDB lists | HU_GENOTOXIC_DAMAGE_24HR | 30 | 8 | 15632 | 1249 |
Slc7a5,Isg15,Dnaja1,Serpinb9,Mthfd2,Psat1,Casp1,Tmod3 |
| 1.944e-03 | -6.24 | regulation of lipid transport | biological process | GO:0032368 | 115 | 17 | 20694 | 1406 |
Irs2,Il1a,P2ry2,Syk,Edn1,Ptch1,Itgav,Acsl5,Fabp3,Nr1h3,Il1b,Kdm5b,Nfkbia,Ttc39b,Lipg,Thbs1,Sirt1 |
| 1.952e-03 | -6.24 | carbohydrate binding | molecular function | GO:0030246 | 269 | 32 | 20217 | 1400 |
Gys1,Hk2,Gbe1,Plod2,Lgals9,Hk3,Clec4n,P4ha2,Gfpt1,Clec4d,Olr1,Hk1,Plod3,Clec2d,Clec5a,Cd302,Siglece,Clec4e,Ly75,Layn,Egln3,Klrk1,Phyh,P4ha1,Adgrl2,Cd34,Vcan,Sele,Klra2,Cd69,Sell,Pfkl |
| 1.959e-03 | -6.24 | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_DN | 178 | 26 | 15632 | 1249 |
Fchsd2,Ikzf1,Chst11,Rnf114,Ifnar1,Cenpe,Gsdmd,Pde3b,Nod1,Aff1,Slco3a1,Dtx3l,Pikfyve,Gbp3,Usp18,Kdm4a,Phip,Card6,Sesn3,Brwd3,Arid4a,Lgals9,Lcp2,Dek,Ap3m2,Slc43a3 |
| 1.959e-03 | -6.24 | GSE17721_LPS_VS_POLYIC_1H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_1H_BMDC_DN | 178 | 26 | 15632 | 1249 |
Acvr1b,C3,Parp3,Crkl,Abcc1,Plekhn1,Gcnt2,Cd300lf,Spint2,Trip13,Zc3h7a,Spen,Sell,Socs1,Xrn1,Gda,Bfar,Rnf34,Hinfp,Birc2,Psmb9,Ctu1,Gadd45g,Ap3b1,Rhoq,Tnc |
| 1.959e-03 | -6.24 | GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_UP | MSigDB lists | GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_UP | 178 | 26 | 15632 | 1249 |
Ddx4,Slc29a3,Serpinb2,Ppfibp2,Gng12,Ahrr,Slc12a9,Arid4a,Jarid2,Atp6v1d,Adap2,Stxbp3,St3gal5,Pstpip2,Ube2l6,Marcksl1,Ifih1,Ccl22,Gnb4,Armcx6,Dusp1,Rab11fip1,Gpr35,Lrch1,Rsad2,Ogfrl1 |
| 1.959e-03 | -6.24 | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 178 | 26 | 15632 | 1249 |
Ube2f,Tab2,Hif1a,Coa5,Ccnd2,Ccl22,Nfkbil1,Psme1,Rars,Rffl,Cd40,Plekha5,Ppp1r14b,Esd,Fam162a,Slfn3,Rcan1,Il2rg,Wars,Hivep3,Pou2f2,Tbc1d13,Psme2,Slfn4,Ankib1,Tnfrsf1b |
| 1.959e-03 | -6.24 | GSE3982_BCELL_VS_TH1_DN | MSigDB lists | GSE3982_BCELL_VS_TH1_DN | 178 | 26 | 15632 | 1249 |
Sap30,Il18rap,Rnf19a,Tap2,Hopx,Ccl4,Il15ra,Ptgir,Slc31a1,Slc25a22,Ak4,Slc43a3,Rnf24,Spry2,Optn,Cst7,Spsb1,D16Ertd472e,Pde3b,Tap1,Hk3,Atp2b4,Nupr1,Plk3,St3gal6,Pttg1 |
| 1.959e-03 | -6.24 | ZWANG_EGF_INTERVAL_DN | MSigDB lists | ZWANG_EGF_INTERVAL_DN | 178 | 26 | 15632 | 1249 |
Zc3h12a,Cdc42ep4,Irf1,Tnfsf10,Ralgds,Rbms1,Glrx,Junb,Ifit1bl2,Abtb2,Nos2,Serpine1,Samsn1,Daam1,Slpi,Zfp36,Bcl9,Spata13,Klf8,Plau,Phldb1,Klf3,Spsb1,Ifit1bl1,Casz1,Kdm5b |
| 1.959e-03 | -6.24 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_DN | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_DN | 178 | 26 | 15632 | 1249 |
Btg2,Cd69,Stx11,Map4k4,Klf2,Ppp1r15a,Osm,Fosb,Trem1,Ptger4,H2-Ab1,Cd55,Fam53c,Oasl1,Dnaja2,Ptgs2,Ifrd1,Crbn,Nr4a1,Dusp1,Tiparp,Serp1,Csf3r,Gbp2,Prnp,Cd74 |
| 1.962e-03 | -6.23 | regulation of transmembrane transport | biological process | GO:0034762 | 567 | 57 | 20694 | 1406 |
Hap1,Kcnj2,Stoml1,Gem,Cacnb3,Cox17,Thbs1,Prnp,Kcna3,Scn1b,Ptafr,Cxcl10,Acsl5,Pid1,Trib3,Il1b,Mmp9,Cav1,Lyn,Prkce,Slc31a2,Nr4a3,Ahr,Hk2,Gja1,Crbn,Glrx,Tlr9,Slc30a1,Adrb2,Slc9a1,Met,Ccl2,Gpr35,Rtn2,Cacna1d,Tnf,Cx3cl1,Ubash3b,Atp2b4,Abcb1a,C3,Clic5,Agrn,Myc,Pde4b,Actb,Irs2,Hvcn1,Hk1,Clic4,Nlgn2,Hspa2,Homer1,Rhoq,Edn1,Stxbp3 |
| 1.964e-03 | -6.23 | NAKAMURA_ADIPOGENESIS_EARLY_UP | MSigDB lists | NAKAMURA_ADIPOGENESIS_EARLY_UP | 51 | 11 | 15632 | 1249 |
Ccrl2,Cebpd,Nfil3,Zfp36,Myc,Ppp2r1b,Irs2,Gadd45b,Myadm,Usp53,Sod2 |
| 1.964e-03 | -6.23 | GO_POSITIVE_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY | 51 | 11 | 15632 | 1249 |
Pdgfrb,Gna15,Ccl5,Flt1,Sele,Prkce,Ptafr,Lpar1,Htr2b,Htr2a,Arf4 |
| 1.964e-03 | -6.23 | PID_KIT_PATHWAY | MSigDB lists | PID_KIT_PATHWAY | 51 | 11 | 15632 | 1249 |
Socs1,Map2k1,Lyn,Crkl,Stat5a,Stat1,Spred1,Stat3,Jak2,Stap1,Kitl |
| 1.964e-03 | -6.23 | GO_RESPONSE_TO_ORGANOPHOSPHORUS | MSigDB lists | GO_RESPONSE_TO_ORGANOPHOSPHORUS | 133 | 21 | 15632 | 1249 |
Ass1,Casp1,Ccl12,Ezr,Junb,Dusp1,Birc2,Fosb,Jun,Fos,P2ry12,Rapgef2,Stat1,Ldha,Ptafr,Sphk1,Sell,Lpar1,Ptgs2,Sdc1,Il1b |
| 1.964e-03 | -6.23 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN | 133 | 21 | 15632 | 1249 |
Dusp16,Plaur,Plekhn1,Pgk1,Itga4,Klf8,Isg15,Sertad3,Ddit4,Ube2l6,Scn1b,Rtn2,Lztfl1,Ccrl2,Spint2,Fzd1,P4ha2,Apobec3,Cav1,Ppm1k,Hmga1 |
| 1.965e-03 | -6.23 | negative regulation of peptidase activity | biological process | GO:0010466 | 263 | 31 | 20694 | 1406 |
Birc3,Plaur,Nr4a1,Thbs1,Src,Hspa1b,Cflar,Bcl2a1d,Rffl,Adora2a,Serpinb6b,Serpina3g,Serpina3f,Ptgs2,Slpi,Il6,Rnf34,C3,Cst7,Serpinb9b,Mdm2,Mmp9,Cdkn2d,Serpine1,Tnfsf14,Serpinb9,Birc2,Spint2,Prdx5,Serpinb2,Timp1 |
| 1.984e-03 | -6.22 | ESC_V6.5_UP_LATE.V1_DN | MSigDB lists | ESC_V6.5_UP_LATE.V1_DN | 169 | 25 | 15632 | 1249 |
Serpine1,Plekha4,Fzd5,Smpdl3b,Inhba,Pdss1,Ttc39b,Ddx4,Lox,Trib3,Socs3,Timp1,Trmt1l,Aoah,Myc,Mdn1,Ggct,Kat2b,Icam1,Nupr1,Plk3,Pdgfc,Cd38,Gys1,Rbm43 |
| 1.992e-03 | -6.22 | GO_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY | MSigDB lists | GO_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY | 142 | 22 | 15632 | 1249 |
Wdr43,Lhx2,Ccl4,Clic4,Ust,Arf4,Fscn1,Rpgrip1l,Pdzd11,Frmd4a,Ptk2,Syne2,Rictor,Rab10,Slc9a1,Mark2,Mpp7,Cyth3,Spry2,Gpsm2,Spn,Ezr |
| 1.999e-03 | -6.22 | regulation of transcription from RNA polymerase II promoter in response to stress | biological process | GO:0043618 | 51 | 10 | 20694 | 1406 |
Jun,Atf3,Notch1,Hmox1,Egr1,Cited2,Klf2,Nck1,Hif1a,Ppp1r15a |
| 2.000e-03 | -6.21 | GSE3982_MAST_CELL_VS_BCELL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_BCELL_DN | 160 | 24 | 15632 | 1249 |
Snn,Il13ra1,Ebi3,Arid5b,Kcna3,Oas2,Ccne1,Hopx,Irf8,Klf2,Adar,Il15,Ppfibp1,Rgs3,Rhoh,Psme1,Evl,Rtp4,Klf8,Il6,Irf4,Fcgr2b,Dhx58,Klhl25 |
| 2.000e-03 | -6.21 | GSE26488_WT_VS_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE26488_WT_VS_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN | 160 | 24 | 15632 | 1249 |
Top3a,Gbp4,Gbp9,Cish,Itpr1,Slc16a3,Ifit2,Cd83,Jmjd6,Rars,Slc7a5,Tnfsf14,Ccl5,Slc7a8,Tnfaip2,Cxcl1,Clcf1,Tnip3,Tgfbi,Rcan1,Ptgs2,Lpar1,Oasl1,Egr3 |
| 2.000e-03 | -6.21 | GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_UP | MSigDB lists | GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_UP | 160 | 24 | 15632 | 1249 |
Treml2,Rasgrp1,Dgka,Ext1,Ikzf1,Egr2,Peli1,Sipa1l1,Lipe,Map4k4,Spred1,Rab3ip,Pmepa1,Rras2,Ikbke,Etv3,Hif1a,Calcrl,Cyth3,Sell,Cdk5r1,Irs2,St3gal1,Rhoh |
| 2.000e-03 | -6.21 | CREBP1_Q2 | MSigDB lists | CREBP1_Q2 | 225 | 31 | 15632 | 1249 |
Agpat4,Ppp2r2a,Sema4c,Egr3,Ell2,Slc31a1,Gng4,Rcan1,Trib1,Nr4a3,Noc4l,Nfkbid,Maff,Ppp1r15a,Fosb,Lmo4,Gem,Rbms2,Slc25a25,Hhex,Abr,Egr1,Ccnd2,Stat3,Egr2,Dusp1,Flt1,Flrt3,Fos,Zmynd15,Rbbp8 |
| 2.001e-03 | -6.21 | protein complex involved in cell adhesion | cellular component | GO:0098636 | 35 | 8 | 20747 | 1409 |
Itga4,Lyn,Cd80,Itga9,Itgal,Itgb8,Itgav,Itga5 |
| 2.006e-03 | -6.21 | positive regulation of vascular smooth muscle cell proliferation | biological process | GO:1904707 | 35 | 8 | 20694 | 1406 |
Nr4a3,Tnf,Jun,Mmp9,Edn1,Jak2,Pdgfb,Mdm2 |
| 2.006e-03 | -6.21 | regulation of anion transmembrane transport | biological process | GO:1903959 | 35 | 8 | 20694 | 1406 |
Acsl5,Irs2,Tnf,Hk1,Thbs1,Abcb1a,Prnp,Ptafr |
| 2.006e-03 | -6.21 | regulation of mast cell activation involved in immune response | biological process | GO:0033006 | 35 | 8 | 20694 | 1406 |
Rabgef1,Hmox1,Adora2b,Lyn,Il4ra,Stxbp1,Fgr,Syk |
| 2.021e-03 | -6.20 | mouse chr4 C4|4 42.03 cM | chromosome location | mouse chr4 C4|4 42.03 cM | 5 | 3 | 24173 | 1464 |
Ifna6,Ifna4,Ifna5 |
| 2.023e-03 | -6.20 | MHC class II protein complex | cellular component | GO:0042613 | 9 | 4 | 20747 | 1409 |
H2-Ab1,H2-Aa,H2-Eb1,Cd74 |
| 2.024e-03 | -6.20 | mouse chr10|10 A1 | chromosome location | mouse chr10|10 A1 | 39 | 8 | 24173 | 1464 |
Mthfd1l,Katna1,Ust,Tab2,Rab32,Lrp11,Plekhg1,Adgb |
| 2.027e-03 | -6.20 | regulation of vitamin D biosynthetic process | biological process | GO:0060556 | 9 | 4 | 20694 | 1406 |
Gfi1,Nfkb1,Il1b,Tnf |
| 2.027e-03 | -6.20 | regulation of hematopoietic stem cell proliferation | biological process | GO:1902033 | 9 | 4 | 20694 | 1406 |
Kitl,Cxcl1,Pim1,Eif2ak2 |
| 2.027e-03 | -6.20 | toll-like receptor 3 signaling pathway | biological process | GO:0034138 | 9 | 4 | 20694 | 1406 |
Lgals9,Tlr3,Cd86,Tnf |
| 2.027e-03 | -6.20 | negative regulation of interleukin-1 beta secretion | biological process | GO:0050713 | 9 | 4 | 20694 | 1406 |
Nlrp3,Zc3h12a,Pml,Tnfaip3 |
| 2.027e-03 | -6.20 | regulation of toll-like receptor 3 signaling pathway | biological process | GO:0034139 | 9 | 4 | 20694 | 1406 |
Peli1,Wdfy1,Cav1,Tnfaip3 |
| 2.027e-03 | -6.20 | aspartate transmembrane transport | biological process | GO:0015810 | 9 | 4 | 20694 | 1406 |
Slc25a12,Slc13a3,Lrrc8c,Slc25a22 |
| 2.027e-03 | -6.20 | oligopeptide transmembrane transport | biological process | GO:0035672 | 9 | 4 | 20694 | 1406 |
Slc7a11,Slco3a1,Slc15a3,Abcc1 |
| 2.027e-03 | -6.20 | heat generation | biological process | GO:0031649 | 9 | 4 | 20694 | 1406 |
Adrb2,Il1a,Il1b,Il1rn |
| 2.027e-03 | -6.20 | CD4-positive, alpha-beta T cell cytokine production | biological process | GO:0035743 | 9 | 4 | 20694 | 1406 |
Il18rap,Il18,Il12b,Dennd1b |
| 2.027e-03 | -6.20 | positive regulation of cellular senescence | biological process | GO:2000774 | 9 | 4 | 20694 | 1406 |
Eef1e1,Cgas,Arg2,Sirt1 |
| 2.027e-03 | -6.20 | response to interleukin-18 | biological process | GO:0070673 | 9 | 4 | 20694 | 1406 |
Il18rap,Il18,Ripk2,Pdgfb |
| 2.027e-03 | -6.20 | positive regulation of fever generation | biological process | GO:0031622 | 9 | 4 | 20694 | 1406 |
Tnf,Il1b,Ptgs2,Ccl5 |
| 2.028e-03 | -6.20 | TACTTGA_MIR26A_MIR26B | MSigDB lists | TACTTGA_MIR26A_MIR26B | 283 | 37 | 15632 | 1249 |
Itga5,Cd200,Dusp5,Rtn1,Larp1,Mtdh,Ptgs2,Phf6,Pim1,Rcn1,Rap2c,Cldnd1,Adam19,Snn,Ccne1,Atm,Nampt,Slc4a7,Eif4g2,Plod2,Cep350,Ep400,G3bp2,Jag1,Usp25,Lif,Nek6,Intu,Ccnd2,Htr2a,Pfkfb3,Slc7a11,Tmem200b,Ehd1,Hmga1,Tmem184b,Kcnj2 |
| 2.032e-03 | -6.20 | RING | smart domains | SM00184 | 228 | 33 | 9567 | 823 |
Bfar,Rnf34,Rnf145,Ankib1,Trim13,Cop1,Birc3,Rnf139,Pcgf5,Traf5,Mid1,Znrf1,Rnf19a,Dtx3l,Birc2,Rnf135,Rnf19b,Dtx2,Trim34a,Traf2,Trim36,Znrf3,Trim26,Trim30d,Rnf114,Trim21,Rffl,Pml,Trim30a,Trim12c,Rnf24,Trim56,Trim12a |
| 2.034e-03 | -6.20 | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN | 197 | 28 | 15632 | 1249 |
Atp6v1d,Cnp,Hk1,Rnf14,Abtb2,Wars,Slc31a1,Etnk1,Casp7,Acsl5,Actb,Hmga1,Dnaja1,Ppp1r14b,P4ha2,Cenpe,Hspa2,Cycs,Casp3,Rtp4,Traf1,Cd74,Cd38,Tnfrsf8,Ahsa1,Batf,Sgcb,Extl2 |
| 2.042e-03 | -6.19 | cell-cell junction | cellular component | GO:0005911 | 472 | 49 | 20747 | 1409 |
Slc9a1,Micall2,Fzd5,Myadm,F11r,Fabp7,Kcnj2,Tnks1bp1,Pvr,Ccnd1,Slc2a1,Nck1,Pkp4,Nectin4,Itgal,Lcp2,Zyx,Scn1b,Keap1,Dst,Ptk2,Usp53,Mtdh,Nectin2,Frmd6,Rpgrip1l,Rap2c,Lyn,Itga4,Clmp,Flrt3,Mmp13,Cdc42ep4,Flrt2,Clic4,Fscn1,Cyth3,Rapgef2,Ptprj,Frmd4a,Pdzd11,Vasp,Mpp7,Ddx58,Abcb1a,Pdlim7,Itga5,Pikfyve,Gja1 |
| 2.050e-03 | -6.19 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | 116 | 19 | 15632 | 1249 |
Rbl1,Adam19,Tnfaip2,Pcdh7,Vcam1,Marcksl1,Evl,Ccnd1,Phlda1,Pdpn,Plscr1,Fut8,Casp4,Tiparp,Timp1,Myo1b,Gja1,Ccl12,Nfkbia |
| 2.055e-03 | -6.19 | ACCAAAG_MIR9 | MSigDB lists | ACCAAAG_MIR9 | 454 | 54 | 15632 | 1249 |
Atp11a,Tab2,Prdm1,Zfp319,Crim1,Pdgfc,Bcl6,Dse,P4ha2,Axl,Aebp2,Dbnl,Rnf24,Gpr85,Tgfbi,Pcgf5,Larp1,Dio2,Igf2bp2,Ralgds,Kitl,Pcdh7,Osbpl3,Pdgfrb,Gch1,Slc31a2,Pde7b,Zfp324,Xrn1,Ubash3b,Mapkapk2,Foxp4,Col4a2,Flrt3,Ap3b1,Kcnj2,Mthfd2,Acvr1b,Itpkc,Egr3,Cpeb4,Frmd6,Rap2c,Notch2,Dr1,Sh3bgrl2,Rims3,Cep350,Nfkb1,Kctd12,Slc39a14,Sirt1,Rnf19a,Slc9a1 |
| 2.058e-03 | -6.19 | ST_T_CELL_SIGNAL_TRANSDUCTION | MSigDB lists | ST_T_CELL_SIGNAL_TRANSDUCTION | 44 | 10 | 15632 | 1249 |
Rasgrp1,Nfkbie,Nfkb2,Nfkbib,Prdx1,Lcp2,Nfkb1,Nfkbil1,Nck1,Nfkbia |
| 2.058e-03 | -6.19 | GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY | 44 | 10 | 15632 | 1249 |
Pdgfrb,Fgr,Pik3r6,Lyn,Pik3r5,Flt1,Ptk2,Src,Nod2,Pdgfb |
| 2.058e-03 | -6.19 | DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP | MSigDB lists | DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP | 44 | 10 | 15632 | 1249 |
Sla,Gca,Atp2b4,Cst7,Plac8,S100a8,Ptger4,Cd302,Csf3r,Samsn1 |
| 2.058e-03 | -6.19 | GO_NON_MEMBRANE_SPANNING_PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | GO_NON_MEMBRANE_SPANNING_PROTEIN_TYROSINE_KINASE_ACTIVITY | 44 | 10 | 15632 | 1249 |
Eif2ak2,Ptk2,Src,Syk,Ripk2,Fgr,Lyn,Jak2,Hck,Tyk2 |
| 2.059e-03 | -6.19 | phosphatase complex | cellular component | GO:1903293 | 43 | 9 | 20747 | 1409 |
Ppp1r15b,Ppp1r15a,Ppp2r2a,Itpr1,Nck1,Ppp2r1b,Ppp2r5a,Ppp2r3a,Ppp4r2 |
| 2.059e-03 | -6.19 | protein serine/threonine phosphatase complex | cellular component | GO:0008287 | 43 | 9 | 20747 | 1409 |
Ppp1r15b,Ppp1r15a,Ppp2r2a,Itpr1,Nck1,Ppp2r1b,Ppp2r5a,Ppp2r3a,Ppp4r2 |
| 2.062e-03 | -6.18 | SCHEIDEREIT_IKK_TARGETS | MSigDB lists | SCHEIDEREIT_IKK_TARGETS | 18 | 6 | 15632 | 1249 |
Nfkb2,Nfkb1,Nfkbib,Nfkbia,Nfkbid,Ccnd1 |
| 2.062e-03 | -6.18 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_DN | 18 | 6 | 15632 | 1249 |
Rgl1,Pml,Rgs3,Rnf145,B3gnt5,Slc30a1 |
| 2.062e-03 | -6.18 | GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | 18 | 6 | 15632 | 1249 |
Htra1,Dhx58,Eif2ak2,Ifit1bl2,Ifit1bl1,Mul1 |
| 2.062e-03 | -6.18 | GO_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | 18 | 6 | 15632 | 1249 |
Dennd1b,Cd55,Tlr2,Nod2,Trem1,Sirt1 |
| 2.062e-03 | -6.18 | HOFMANN_MYELODYSPLASTIC_SYNDROM_RISK_DN | MSigDB lists | HOFMANN_MYELODYSPLASTIC_SYNDROM_RISK_DN | 18 | 6 | 15632 | 1249 |
Lcp2,Stat2,Pf4,Dyrk2,Ifnar1,Rhoh |
| 2.062e-03 | -6.18 | BIOCARTA_ETS_PATHWAY | MSigDB lists | BIOCARTA_ETS_PATHWAY | 18 | 6 | 15632 | 1249 |
Csf1,Fos,Etv3,Rbl1,Jun,Ets2 |
| 2.062e-03 | -6.18 | GO_FILOPODIUM_MEMBRANE | MSigDB lists | GO_FILOPODIUM_MEMBRANE | 18 | 6 | 15632 | 1249 |
Vasp,Syne2,Myo10,Pdpn,Antxr1,Itgav |
| 2.062e-03 | -6.18 | SMID_BREAST_CANCER_RELAPSE_IN_PLEURA_DN | MSigDB lists | SMID_BREAST_CANCER_RELAPSE_IN_PLEURA_DN | 18 | 6 | 15632 | 1249 |
Cp,Slpi,Bambi,Fabp7,H2-Ab1,Psat1 |
| 2.062e-03 | -6.18 | GO_REGULATION_OF_MYOBLAST_FUSION | MSigDB lists | GO_REGULATION_OF_MYOBLAST_FUSION | 18 | 6 | 15632 | 1249 |
Gdf15,Cflar,Ehd1,Cxcl10,Il4ra,Tnfsf14 |
| 2.062e-03 | -6.18 | BIOCARTA_CARDIACEGF_PATHWAY | MSigDB lists | BIOCARTA_CARDIACEGF_PATHWAY | 18 | 6 | 15632 | 1249 |
Myc,Nfkb1,Ednrb,Edn1,Jun,Fos |
| 2.062e-03 | -6.18 | SCIBETTA_KDM5B_TARGETS_UP | MSigDB lists | SCIBETTA_KDM5B_TARGETS_UP | 18 | 6 | 15632 | 1249 |
Smox,Ehd1,Rnaset2a,Sat1,Clcf1,Rnaset2b |
| 2.062e-03 | -6.18 | BIOCARTA_TH1TH2_PATHWAY | MSigDB lists | BIOCARTA_TH1TH2_PATHWAY | 18 | 6 | 15632 | 1249 |
Il12b,Cd40,Il4ra,Il18,Cd86,Il12rb1 |
| 2.065e-03 | -6.18 | regulation of T cell apoptotic process | biological process | GO:0070232 | 43 | 9 | 20694 | 1406 |
Arg2,Hif1a,Nfkbid,Casp8,Tnfsf4,Cd274,Ripk3,Ccl5,Serpinb9 |
| 2.066e-03 | -6.18 | GO_MYELOID_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_MYELOID_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 37 | 9 | 15632 | 1249 |
Rasgrp1,Prkce,Stxbp3,Nr4a3,Lyn,Pik3cd,Syk,Tlr3,Cx3cr1 |
| 2.066e-03 | -6.18 | BIOCARTA_P38MAPK_PATHWAY | MSigDB lists | BIOCARTA_P38MAPK_PATHWAY | 37 | 9 | 15632 | 1249 |
Stat1,Mapkapk2,Max,Map2k4,Traf2,Myc,Pla2g4a,Daxx,Rapgef2 |
| 2.066e-03 | -6.18 | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_REGULATOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | MSigDB lists | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_REGULATOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | 37 | 9 | 15632 | 1249 |
Casp1,Birc3,Birc2,Serpinb9,Tnfsf14,Nod1,Casp3,Prdx5,Apaf1 |
| 2.066e-03 | -6.18 | GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION | 37 | 9 | 15632 | 1249 |
Peli1,Clcf1,Cdkn1a,Bst1,Cd38,Cd40,Bcl6,Irs2,Cd74 |
| 2.067e-03 | -6.18 | Signaling by VEGF | REACTOME pathways | R-MMU-194138 | 295 | 41 | 8608 | 757 |
Vegfc,Ksr1,Flt1,Il2rg,Pdgfrb,Ppp2r1b,Axl,Kdr,Jak2,Map2k1,Itgav,Spred1,Kitl,Pdgfb,Angpt1,Rictor,Psme2b,Irs2,Ppp2r5a,Src,Mapkapk2,Rapgef2,Nrp2,Rasgrp1,Psmb9,Cyfip1,Psme1,Dusp5,Sphk1,Psmb6,Dusp6,Psmb10,Nck1,Ptk2,Met,Psmb8,Cav1,Psmd10,Psme2,Psma6,Trib3 |
| 2.070e-03 | -6.18 | regulation of animal organ morphogenesis | biological process | GO:2000027 | 209 | 26 | 20694 | 1406 |
Edn1,Bcor,Itpr1,Csf1,Pim1,Tnfaip3,Myc,Sec24b,Notch1,Hmga2,Casz1,Znrf3,Lif,Cited2,Jag1,Tnf,Cflar,Fzd1,Met,Plau,Cd34,Sema3c,Bmp2,Etv5,Acvr1,Pml |
| 2.073e-03 | -6.18 | embryo development ending in birth or egg hatching | biological process | GO:0009792 | 828 | 78 | 20694 | 1406 |
Hopx,Fzd1,Inpp5b,Socs3,Cited2,Tulp3,Phactr4,Sdc4,Vezt,Hinfp,Acvr1,Intu,Rbbp8,Il10,Casp8,Phf6,Angpt1,Spic,Acvrl1,Apaf1,Slc30a1,Ift57,Prdm1,Med21,Notch2,Eno1,Vcam1,Sema4c,Ext1,Edn1,Klf2,Zeb1,Mmp14,Junb,Pdgfrb,Fzd5,Rpgrip1l,Ifitm1,Sec24b,Itga4,Plod3,Phgdh,Mgat1,Vasp,Acvr1b,Hif1a,Mthfr,Mafg,Lif,Pdgfb,Atm,Map2k1,Bmp2,Bcl2l11,Hsd17b7,Sema3c,Lhx2,Keap1,Rcn1,Cdk5r1,Maff,Adar,Pbx1,Rictor,Chst11,Atp11a,Sbds,Spint2,Itgav,Ptch1,Lmo4,Gja1,Bcor,Casp3,Notch1,Hhex,Mthfd1l,Apba1 |
| 2.082e-03 | -6.17 | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | 188 | 27 | 15632 | 1249 |
Pdzd11,Ier3,Fndc3a,Nfil3,Pmepa1,Arf4,Atp6v1d,Gja1,Car13,Prnp,Hif1a,Lif,Hvcn1,Ripk3,Spred1,Myo10,Rbms2,Tspo,Tiparp,Trip10,Tmem184b,Aebp2,Glipr2,Gadd45g,Acvrl1,Tbc1d1,Rffl |
| 2.082e-03 | -6.17 | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_UP | 188 | 27 | 15632 | 1249 |
Adap2,Nos2,Casp8,Snx10,Ccr1,S100a8,Tmem26,Slc9a1,Arid5b,Il18,Ttc39b,Cd200,Zc3h12a,Cd82,Spic,Casz1,Axl,Cnot4,Cxcl14,Stard5,Nr1h3,Pdgfc,Cd38,Klf7,Zbtb5,Mapkbp1,Sdc4 |
| 2.082e-03 | -6.17 | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | 188 | 27 | 15632 | 1249 |
Gpd2,Fndc3a,Tagap,Osbpl3,Il1rn,Fam102b,Gcnt2,Cd86,Plekha2,Ptch1,Birc3,Nfkb1,P4ha1,AA467197,Zeb1,Ubash3b,Kat2b,Notch1,Spred1,Cd38,Vcpip1,Gclc,Tspo,Timp1,Cenpe,Plekhf2,Acvr1 |
| 2.082e-03 | -6.17 | GSE2826_WT_VS_BTK_KO_BCELL_UP | MSigDB lists | GSE2826_WT_VS_BTK_KO_BCELL_UP | 188 | 27 | 15632 | 1249 |
Ebi3,Cd200,Ldha,Bcl2a1a,Fam162a,Cep350,Dmwd,Casp4,Zeb1,Timeless,Plscr1,Dgka,Ier2,Rhoh,Mcoln2,Crlf3,Cd83,Me1,Relb,Hivep2,Bcl2a1b,Ankrd17,Tcf4,Bcl6,Il4i1,Mecp2,Bcl2a1d |
| 2.082e-03 | -6.17 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_UP | 188 | 27 | 15632 | 1249 |
Mcoln2,Slc30a4,Prdm1,Vcpip1,Rapgef5,Cenpe,Klf6,Itpr1,Gbp9,Lrch1,Gbp4,Top3a,Cdyl2,Pim2,Sema4a,Mob3b,Tmem229b,4930453N24Rik,Frmd6,Pkp4,Gng12,Sipa1l1,Fzd5,Tnfsf14,Slpi,Il18rap,Kctd12 |
| 2.093e-03 | -6.17 | hepaticobiliary system development | biological process | GO:0061008 | 106 | 16 | 20694 | 1406 |
Cited2,Itpr1,Jun,Hlx,Sod2,Notch2,Ahr,Ccnd1,Hmox1,Rpgrip1l,Met,Hp,Jarid2,Tet2,Notch1,Hhex |
| 2.093e-03 | -6.17 | reactive oxygen species metabolic process | biological process | GO:0072593 | 106 | 16 | 20694 | 1406 |
Txnrd1,Ddit4,Bnip3,Slc7a2,Prdx1,Nqo1,Met,Cycs,Sod2,Nos2,Tlr2,Pdgfb,Nox1,Prdx5,Edn1,Tlr6 |
| 2.099e-03 | -6.17 | neuron differentiation | biological process | GO:0030182 | 1044 | 95 | 20694 | 1406 |
Lrp4,Dst,Scn1b,Lif,Pdgfb,Map2k1,Dock10,Micall2,Hap1,Lst1,Stat3,Sema3c,Map4k4,Inhba,Jak2,Flrt3,Crkl,Scarf1,Notch1,Gfi1,Adora2a,Ehd1,Kif5c,Tnc,Mecp2,Tulp3,Ddit4,Sdc2,Cnp,Hdac1,Evl,Lrp8,Fas,Igsf9,Flrt2,Ntng2,Tsku,Triobp,D16Ertd472e,Rac3,Clic5,Ptk2,Itga4,Phgdh,Jag1,Vasp,Mturn,Ier2,Hif1a,Casz1,Il6,Cyfip1,Sema4a,Nrp2,Rapgef2,Lhx2,Nr4a3,Spire1,Cdk5r1,Klf7,Lyn,Lmo4,Gja1,Ptch1,Casp3,Dbnl,Ppp2r3a,Palld,Btg2,Arf4,Jun,Sod2,Stxbp1,Egr2,Kdr,Sdc4,Fcgr2b,Met,Ikzf1,Prdm1,Rab10,Uchl1,Zhx2,Ext1,Tmem67,Vcam1,Igf1r,Psd,Agrn,Rnd1,C3,Mark2,Actb,Slc4a7,Sec24b |
| 2.106e-03 | -6.16 | BIOCARTA_TPO_PATHWAY | MSigDB lists | BIOCARTA_TPO_PATHWAY | 24 | 7 | 15632 | 1249 |
Jak2,Stat3,Stat1,Stat5a,Jun,Map2k1,Fos |
| 2.106e-03 | -6.16 | GO_APOPTOTIC_CELL_CLEARANCE | MSigDB lists | GO_APOPTOTIC_CELL_CLEARANCE | 24 | 7 | 15632 | 1249 |
Thbs1,Itgav,Xkr8,Axl,Jmjd6,Nr1h3,Marco |
| 2.106e-03 | -6.16 | XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR | MSigDB lists | XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR | 24 | 7 | 15632 | 1249 |
Upp1,Jun,Ehd1,Plaur,Plau,Pfkfb3,Sat1 |
| 2.106e-03 | -6.16 | REACTOME_BASIGIN_INTERACTIONS | MSigDB lists | REACTOME_BASIGIN_INTERACTIONS | 24 | 7 | 15632 | 1249 |
Cav1,Spn,Slc7a8,Slc16a3,Slc7a11,Slc16a1,Slc7a5 |
| 2.106e-03 | -6.16 | PID_INTEGRIN_A9B1_PATHWAY | MSigDB lists | PID_INTEGRIN_A9B1_PATHWAY | 24 | 7 | 15632 | 1249 |
Vcam1,Sat1,Tnc,Vegfc,Src,Itga9,Nos2 |
| 2.106e-03 | -6.16 | PID_TRAIL_PATHWAY | MSigDB lists | PID_TRAIL_PATHWAY | 24 | 7 | 15632 | 1249 |
Cflar,Ikbkg,Tnfsf10,Traf2,Map2k4,Pik3cd,Casp8 |
| 2.106e-03 | -6.16 | GO_MHC_PROTEIN_BINDING | MSigDB lists | GO_MHC_PROTEIN_BINDING | 24 | 7 | 15632 | 1249 |
Pilrb1,Pilra,Pilrb2,Tapbp,Tap1,Cd74,Tap2 |
| 2.106e-03 | -6.16 | GO_FIBRONECTIN_BINDING | MSigDB lists | GO_FIBRONECTIN_BINDING | 24 | 7 | 15632 | 1249 |
Itga4,Hsd17b12,Sdc4,Itgav,Thbs1,Mmp13,Plekha2 |
| 2.106e-03 | -6.16 | CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_DN | 24 | 7 | 15632 | 1249 |
Plod2,Rcn1,Homer1,Card6,Dram1,Cers6,Bambi |
| 2.106e-03 | -6.16 | ZHENG_FOXP3_TARGETS_UP | MSigDB lists | ZHENG_FOXP3_TARGETS_UP | 24 | 7 | 15632 | 1249 |
Lrrc8c,Abcb1a,Ubash3b,Map3k8,Prdm1,P4ha1,Rhoh |
| 2.116e-03 | -6.16 | PROVENZANI_METASTASIS_DN | MSigDB lists | PROVENZANI_METASTASIS_DN | 125 | 20 | 15632 | 1249 |
Ak4,Rcn1,Ccnd2,Slco3a1,Pdgfc,Col4a2,Sdc4,Notch2,Tnip1,Slc48a1,Tnfaip2,Psmb9,Lcn2,Serpine1,Slc2a1,P4ha2,Plod3,Ccnd1,Spint2,Nmi |
| 2.119e-03 | -6.16 | Stabilization of p53 | REACTOME pathways | R-MMU-69541 | 54 | 12 | 8608 | 757 |
Psme2b,Psmd10,Psma6,Psme2,Psmb10,Psmb8,Mdm2,Psme1,Psmb6,Psmb9,Atm,Cop1 |
| 2.122e-03 | -6.16 | GSE29618_BCELL_VS_PDC_DN | MSigDB lists | GSE29618_BCELL_VS_PDC_DN | 179 | 26 | 15632 | 1249 |
Mapkapk2,Dnase1l3,Ppp1r14b,Slc7a11,Trip10,Tcf4,Irf4,Ctsc,Sema4c,Dusp5,Mcm6,Cmklr1,Txn1,Dach1,Plek,Sema3c,Irf8,Gna15,Higd1a,Rims3,Irf7,Slc7a5,Flnb,Sh3bp4,Egln3,Etv6 |
| 2.122e-03 | -6.16 | GSE3982_DC_VS_BASOPHIL_UP | MSigDB lists | GSE3982_DC_VS_BASOPHIL_UP | 179 | 26 | 15632 | 1249 |
Rtn2,Ppp2r3a,Inhba,Wars,Hivep3,Cdyl,Atp6v1d,Ascc3,Il10,Esd,Slc31a1,Atp10a,Dram1,Rai14,Spry2,Nqo1,Phactr4,Cers6,Spsb1,Eno1,Cd83,Hck,Stxbp1,Atf3,Kmo,Ccl22 |
| 2.122e-03 | -6.16 | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_UP | MSigDB lists | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_UP | 179 | 26 | 15632 | 1249 |
Asf1a,Rap2c,Nlgn2,Dtx2,Atxn7l1,Ep400,Ampd3,Tmem176a,Pde4b,Gch1,Ppp1r15a,Casp4,Tmem176b,Ccnd2,1110038F14Rik,Egr2,Rai14,Ap3b1,Ccnd1,Cept1,Ifit2,Gypc,Clmp,Bcl2l11,Fos,B4galt4 |
| 2.122e-03 | -6.16 | GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | 179 | 26 | 15632 | 1249 |
Egr2,Chst11,Taf4b,Aebp2,Gadd45g,Bcl2a1d,Bcl2a1b,Rgs14,Itpr1,Ciita,Cd83,Myo10,Tle3,Zfp281,Gmppb,Icosl,Wdfy1,Hivep3,Stx11,Snx10,Brd2,Lap3,Bcl2a1a,Fscn1,Fmnl2,Osgin2 |
| 2.122e-03 | -6.16 | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_DN | MSigDB lists | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_DN | 179 | 26 | 15632 | 1249 |
Frmd6,Orai2,Fam102b,Ust,Cdc42ep4,Tnfsf4,Atp10a,Il18rap,AA467197,Rap1gap2,Osm,Nod1,Rras2,P2ry14,Itga4,Glipr2,Acvrl1,Dock10,Irf4,Cish,Gpr18,D16Ertd472e,Axl,Dpy19l1,Pik3r5,Bcl2l11 |
| 2.122e-03 | -6.16 | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP | 179 | 26 | 15632 | 1249 |
Cd274,Samsn1,Tap2,Igsf8,Irf7,Ahrr,Pla2g7,Pde7b,Alas1,Mppe1,Tapbpl,Endod1,Socs7,Rbms1,Tnip1,Psmb9,Klf3,Ddhd1,Ap3b1,Nr3c1,1110038F14Rik,Dusp2,Cd74,Nfkbil1,Notch1,Prpf4 |
| 2.122e-03 | -6.16 | GSE27786_BCELL_VS_CD4_TCELL_DN | MSigDB lists | GSE27786_BCELL_VS_CD4_TCELL_DN | 179 | 26 | 15632 | 1249 |
Hmox1,Cox18,Ttc39b,Bcl2a1a,Znrf1,Rgs1,Ifit1bl2,Tshz1,Itgal,Plscr1,Rnf19a,Il18rap,Tmem176b,Itga4,Plau,Ccdc88b,1600014C10Rik,Klf3,Ifit1bl1,Pik3r5,Bcl2a1b,Abcc5,Cyfip1,Birc2,Mllt6,Bcl2a1d |
| 2.122e-03 | -6.16 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_UP | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_UP | 179 | 26 | 15632 | 1249 |
Usp53,Klf6,Spsb1,Parp14,Chst11,Cd200r4,P2ry14,Pttg1,Atp11a,Gpc1,Cutc,Fbxo4,Sesn3,Daam1,Hopx,Nmi,Srxn1,Ext1,Il18rap,Stoml1,Fcho2,Mppe1,Grina,Ust,Fam20c,Cmpk2 |
| 2.123e-03 | -6.15 | MODULE_11 | MSigDB lists | MODULE_11 | 496 | 58 | 15632 | 1249 |
Stat2,Rnd1,Mthfr,Nupr1,Etv5,Myo10,Itpr1,Mtus1,Bcl6,Tnf,Abcc5,Ccnd1,Hspa2,D1Ertd622e,Tnc,Dusp8,Rtn1,Gng4,Rsbn1,Inpp1,Hopx,Cnp,Atp6v1d,Ifit1bl2,Pde4b,Gja1,Stoml1,Hap1,Scn1b,Ccnd2,Angpt1,Gclc,Fos,Ifit1bl1,Cx3cr1,Vcan,Psd,Dtnb,Cacnb3,Acsl1,Egr3,Rac3,Kif5c,Cd200,Ell2,Lhx2,Dnajb2,Ap3m2,Rgs1,Rims3,Lmo4,Eno2,Ednrb,Mmd,Bcl9,Fabp7,Ppp4r2,St3gal5 |
| 2.128e-03 | -6.15 | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 | MSigDB lists | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 | 245 | 33 | 15632 | 1249 |
C1rl,Btg2,Isg20,Trim26,Tapbpl,Tnip3,Pim2,Snn,Ldlr,Sec24a,Orai2,Ptpn2,D16Ertd472e,Sod2,N4bp1,Dtnb,Ogfrl1,Chst11,Rhoq,Mmp14,Irf4,Dmxl2,Ccnd2,Cd180,Rhoh,Nck1,Prdm1,Vcpip1,Irak3,Cd38,Slamf7,Cdc42ep2,Zbp1 |
| 2.155e-03 | -6.14 | GSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_UP | MSigDB lists | GSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_UP | 170 | 25 | 15632 | 1249 |
Fpr1,Nr4a3,Dck,Tlr3,Il1rn,Plk2,Fcgr4,Slc31a2,Xaf1,Casp2,Slco3a1,Tlr6,Lif,Nfkbil1,Gng11,Crlf3,Itgav,Ifnar1,Spn,Lipe,Cx3cr1,Acvrl1,Pcx,Vcan,Fchsd2 |
| 2.155e-03 | -6.14 | TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P | MSigDB lists | TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P | 538 | 62 | 15632 | 1249 |
Mafg,Pik3cd,Socs3,Ell2,Cpeb4,Mtdh,Kpna3,Frmd6,Rap2c,Adam19,Arf4,Znrf1,Zcchc2,Jdp2,Dcun1d3,Ednrb,Mier3,Mmd,Sirt1,Bcl9,Ksr1,Spen,Bcor,Sgcb,Extl2,Ptpn2,Bcl2l11,Rab32,Fam43a,Irf4,Arid5b,Fcho2,Phf6,Fndc3a,Pcgf5,Crkl,Naa25,Dio2,Cldnd1,Elmod2,Serpine1,Ascc3,Gja1,Rgl1,Arid4a,Rab10,Tmeff1,Sap30,Nrp2,Ddit4,Socs1,Il1a,Hlx,Ier2,Prdm1,Plagl2,Ube2f,Ankrd17,P4ha2,B3gnt5,Mecp2,Acvr1 |
| 2.158e-03 | -6.14 | GO_PERINUCLEAR_REGION_OF_CYTOPLASM | MSigDB lists | GO_PERINUCLEAR_REGION_OF_CYTOPLASM | 580 | 66 | 15632 | 1249 |
Gbp2,Mvp,Malt1,Apba1,Slc39a13,Gbp3,Sele,Tlk2,Nfkbie,Prdx5,Src,Hspa1a,Osbpl3,Clic4,Sec24a,Pkp4,Sec24b,Ptges,Hmox1,Scyl2,Spire1,Rab10,Rapgef2,Inhba,Oas2,Cnp,Fzd5,Myo1b,Vps54,Cd34,Fas,Trim13,Nmral1,Cx3cl1,Pikfyve,Cdk5r1,Pla2g4a,Prkce,Optn,Ezr,Cx3cr1,Eif2ak2,Ccl12,Cyfip1,Dnaja1,Trip10,Gbp2b,Prkar2b,Cdkn1a,Mtdh,Mtmr14,Stat1,Rac3,Odc1,Lyn,Ddx4,Slc9a1,Csf1,Stx6,Rap1gap2,Tnfrsf1b,Lnpep,Dcun1d3,Cav1,Nos2,Ptch1 |
| 2.158e-03 | -6.14 | MODULE_238 | MSigDB lists | MODULE_238 | 134 | 21 | 15632 | 1249 |
Spint2,Rsad2,Oas1a,Mecp2,Heatr6,Irf8,Flrt2,Abcc5,Plac8,Tap1,5430427O19Rik,Sp110,Hvcn1,Tnfaip2,Cmklr1,Fgr,Il4ra,Rcsd1,Kcna3,Cd200,Oas1g |
| 2.159e-03 | -6.14 | IBR_dom | interpro domains | IPR002867 | 14 | 5 | 19984 | 1430 |
Rnf14,Rnf31,Rnf19a,Ankib1,Rnf19b |
| 2.163e-03 | -6.14 | manganese ion binding | molecular function | GO:0030145 | 59 | 11 | 20217 | 1400 |
Sod2,Lap3,Extl2,Pim1,Fam20c,Arg2,Idi1,Dcp2,Dyrk2,Me1,Mgat1 |
| 2.166e-03 | -6.13 | peptidase regulator activity | molecular function | GO:0061134 | 238 | 29 | 20217 | 1400 |
Serpina3f,Cst7,Birc3,Slpi,C3,Serpinb2,Wfdc17,Serpine1,Apaf1,Birc2,Serpina3g,Bcl2a1d,Serpinb9,Cflar,Mmp25,Ctsc,Ctla2b,Serpinb9b,Psme2,Crim1,Tnfsf14,Pttg1,Prdx5,Tank,Timp1,Cav1,Psme1,Spint2,Serpinb6b |
| 2.167e-03 | -6.13 | FCERI mediated MAPK activation | REACTOME pathways | R-MMU-2871796 | 233 | 34 | 8608 | 757 |
Psmd10,Psma6,Psme2,Psmb10,Psmb8,Met,Ptk2,Dusp5,Psme1,Jun,Dusp6,Lcp2,Psmb6,Rapgef2,Psmb9,Rasgrp1,Psme2b,Fos,Angpt1,Src,Lyn,Ppp2r5a,Irs2,Kitl,Spred1,Map2k4,Pdgfb,Syk,Ppp2r1b,Map2k1,Jak2,Il2rg,Ksr1,Pdgfrb |
| 2.175e-03 | -6.13 | natural killer cell mediated cytotoxicity | biological process | GO:0042267 | 21 | 6 | 20694 | 1406 |
Rnf19b,Raet1e,H60b,Prdx1,Stx11,Il18 |
| 2.175e-03 | -6.13 | post-embryonic animal organ development | biological process | GO:0048569 | 21 | 6 | 20694 | 1406 |
Ahr,Fzd5,Jak2,Kdr,Flt1,Bcl2l11 |
| 2.175e-03 | -6.13 | purinergic nucleotide receptor signaling pathway | biological process | GO:0035590 | 21 | 6 | 20694 | 1406 |
Ptafr,P2ry14,Hcar2,P2ry2,P2ry12,P2ry13 |
| 2.175e-03 | -6.13 | cellular zinc ion homeostasis | biological process | GO:0006882 | 21 | 6 | 20694 | 1406 |
Slc30a1,Mt1,Slc39a13,Slc39a14,Slc39a4,Mt2 |
| 2.175e-03 | -6.13 | regulation of macrophage derived foam cell differentiation | biological process | GO:0010743 | 21 | 6 | 20694 | 1406 |
Il18,Itgav,Msr1,Nfkbia,Pf4,Csf1 |
| 2.175e-03 | -6.13 | positive regulation of fatty acid transport | biological process | GO:2000193 | 21 | 6 | 20694 | 1406 |
Acsl5,Fabp3,P2ry2,Il1a,Edn1,Il1b |
| 2.175e-03 | -6.13 | vascular endothelial growth factor signaling pathway | biological process | GO:0038084 | 21 | 6 | 20694 | 1406 |
Nrp2,Pdgfb,Vegfc,Pdgfrb,Flt1,Kdr |
| 2.175e-03 | -6.13 | TAP complex binding | molecular function | GO:0062061 | 9 | 4 | 20217 | 1400 |
Tapbp,H2-Q6,H2-Q4,H2-Q7 |
| 2.175e-03 | -6.13 | acid phosphatase activity | molecular function | GO:0003993 | 9 | 4 | 20217 | 1400 |
Acpp,Minpp1,Acp2,Acp5 |
| 2.177e-03 | -6.13 | GSE25502_WT_VS_KLF13_KO_THYMIC_MEMORY_LIKE_CD8_TCELL_UP | MSigDB lists | GSE25502_WT_VS_KLF13_KO_THYMIC_MEMORY_LIKE_CD8_TCELL_UP | 161 | 24 | 15632 | 1249 |
Pikfyve,Malt1,Rgs3,P2ry12,Gpr18,Cd302,Spryd7,Bcl2a1b,Acvr1,Bcl2a1d,Nr3c1,Bnip3,Minpp1,Il4i1,Rai14,Slc31a1,Bcl2a1a,Tnfsf10,Spint2,AA467197,Ksr1,Pstpip2,Tmeff1,Tifa |
| 2.177e-03 | -6.13 | GSE6259_BCELL_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_BCELL_VS_CD8_TCELL_DN | 161 | 24 | 15632 | 1249 |
Rapgef2,Phlpp2,Daam1,Ppm1k,Lcp2,Dusp6,Tfec,Tagap,Dcbld2,Idi1,Fam102b,Tlr2,Tnip3,Cebpd,Taf4b,Rhoq,Casp3,Psip1,Rab32,Mdfic,Aff1,Col4a2,Crlf3,Irs2 |
| 2.177e-03 | -6.13 | GO_REGULATION_OF_PROTEIN_BINDING | MSigDB lists | GO_REGULATION_OF_PROTEIN_BINDING | 161 | 24 | 15632 | 1249 |
Itga4,Bmp2,Angpt1,Ifit1bl1,Src,Crbn,Ifit2,Traf2,Mmp9,Adrb2,Aida,Trib3,Bambi,Mitd1,Plcl2,Ifit1bl2,Plk2,Cav1,Il10,Hopx,Slpi,Pdgfb,Csf3,Rapgef2 |
| 2.177e-03 | -6.13 | TRIAD | prosite domains | PS51873 | 13 | 5 | 13278 | 1037 |
Rnf19b,Rnf19a,Rnf31,Ankib1,Rnf14 |
| 2.178e-03 | -6.13 | GO_RESPONSE_TO_AMINO_ACID | MSigDB lists | GO_RESPONSE_TO_AMINO_ACID | 108 | 18 | 15632 | 1249 |
Asns,Tnf,Ccl12,Ass1,Ccl5,Sh3bp4,Casp3,Edn1,Zeb1,Il6,Icam1,Socs1,Lyn,Ptger4,Fas,Cpeb4,Mthfr,Pdgfc |
| 2.181e-03 | -6.13 | GO_RESPONSE_TO_ESTRADIOL | MSigDB lists | GO_RESPONSE_TO_ESTRADIOL | 143 | 22 | 15632 | 1249 |
Dusp1,Ass1,Ccne1,Il10,Ptch1,Casp8,Pdgfrb,Rbbp8,Pdgfb,Casp3,Stat3,Mecp2,Ccnd1,Nqo1,Socs3,C3,Ptgs2,Hif1a,Socs1,Cd38,Ahr,Il1b |
| 2.185e-03 | -6.13 | ruffle membrane | cellular component | GO:0032587 | 69 | 12 | 20747 | 1409 |
Itga5,Src,Spata13,Fgr,Ptprj,Ddx58,Arf4,Psd4,Pdpn,Itgav,Plek,Psd |
| 2.185e-03 | -6.13 | YAMANAKA_GLIOBLASTOMA_SURVIVAL_UP | MSigDB lists | YAMANAKA_GLIOBLASTOMA_SURVIVAL_UP | 8 | 4 | 15632 | 1249 |
Stk40,Itga5,Tpi1,Rab32 |
| 2.186e-03 | -6.13 | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_6H_DN | 152 | 23 | 15632 | 1249 |
Dtx3l,Mpp7,Rhoh,Olfml3,Spred1,Homer1,Plekhf2,Gbp4,Gbp9,Il2rg,Ptafr,Arid5b,Fam111a,Stat1,Wdr43,Tmem123,Asf1a,Cxcl1,Gch1,Rhou,Etv6,Tmeff1,Zeb1 |
| 2.186e-03 | -6.13 | GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN | MSigDB lists | GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN | 152 | 23 | 15632 | 1249 |
Parp10,Trim12c,Slamf7,Il15,Daxx,Agrn,Rnf114,Il4i1,Batf2,Slfn8,Ell2,Ebi3,Slfn9,Epsti1,Rnf31,Gch1,Abtb2,Slc31a2,Ppm1k,Isg20,Slc9a1,Parp12,Il18rap |
| 2.193e-03 | -6.12 | JNK cascade | biological process | GO:0007254 | 69 | 12 | 20694 | 1406 |
Ptk2,Map2k4,Mlkl,Myd88,Ripk2,Mul1,Trib1,Tnf,Mapkbp1,Mdfic,Ptger4,Syk |
| 2.197e-03 | -6.12 | leukocyte apoptotic process | biological process | GO:0071887 | 28 | 7 | 20694 | 1406 |
Crkl,Il6,Myc,Bcl2l11,Fas,Hcar2,Traf3ip2 |
| 2.197e-03 | -6.12 | pericardium development | biological process | GO:0060039 | 28 | 7 | 20694 | 1406 |
Pdpn,Bmp2,Notch1,Rpgrip1l,Itga4,Flrt3,Vcam1 |
| 2.197e-03 | -6.12 | positive regulation of p38MAPK cascade | biological process | GO:1900745 | 28 | 7 | 20694 | 1406 |
Gadd45b,Met,Zc3h12a,Il1b,Bmp2,Gadd45g,Sphk1 |
| 2.197e-03 | -6.12 | regulation of regulatory T cell differentiation | biological process | GO:0045589 | 28 | 7 | 20694 | 1406 |
Socs1,Tnfsf4,Lgals9,Il2rg,Ctla2a,Irf1,Bcl6 |
| 2.197e-03 | -6.12 | negative regulation of cyclin-dependent protein kinase activity | biological process | GO:1904030 | 28 | 7 | 20694 | 1406 |
Actb,Casp3,Hhex,Cdkn2d,Kat2b,Cdkn1a,Tnfaip3 |
| 2.197e-03 | -6.12 | positive regulation of release of cytochrome c from mitochondria | biological process | GO:0090200 | 28 | 7 | 20694 | 1406 |
Plaur,Fas,Fam162a,Mmp9,Tnfsf10,Bcl2l11,Bnip3 |
| 2.206e-03 | -6.12 | MODULE_255 | MSigDB lists | MODULE_255 | 384 | 47 | 15632 | 1249 |
Csf1,Trim14,Timeless,Ppp4r2,Plekhg1,Gem,Lap3,Clcf1,Chd9,Nfil3,Tnfsf4,Mmp9,Sema4a,Acsl1,Mmp14,Hivep2,Morc3,Ccl12,Fos,Cited2,Zbtb5,Slamf7,Ddx60,Phip,Fpr2,Kat2b,Aldh1b1,Tuba4a,Gja1,Larp1,Ptgs2,Cxcl10,Stat3,Kdm5b,Acvr1,Gpr68,Plekhf2,Arid5a,Sav1,Mapkbp1,Smg7,Ncoa7,Mcmbp,Itga4,Prdm1,Il1a,Hif1a |
| 2.218e-03 | -6.11 | AATGTGA_MIR23A_MIR23B | MSigDB lists | AATGTGA_MIR23A_MIR23B | 374 | 46 | 15632 | 1249 |
G3bp2,Map4k4,Gja1,Pde4b,Fosb,Col11a2,Kitl,Rsbn1,Pkp4,Dusp5,Ptger4,Dennd1b,Ccnd1,Mtus1,Mdfic,Marcksl1,Irf2,Magohb,Prdm1,Intu,Kdm4a,Zeb1,Met,Dach1,Asf1a,Adam19,Zcchc2,Egr3,Cpeb4,Casp7,Rcn1,Trib1,Irf1,Stard5,Rai14,Spry2,Klf3,Plau,Rras2,Atp11b,Aff1,Palld,Nek6,Fas,Cdk5r1,Plagl1 |
| 2.225e-03 | -6.11 | SH2 | smart domains | SM00252 | 101 | 18 | 9567 | 823 |
Syk,Src,Nck1,Sla,Lyn,Socs1,Fgr,Rin2,Jak2,Crkl,Socs7,Stap1,Socs3,Cish,Stat2,Hck,Lcp2,Stat5a |
| 2.229e-03 | -6.11 | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | 324 | 41 | 15632 | 1249 |
Casp8,Fzd5,Cav1,Tnfsf14,Rnf31,Hap1,Rhou,Csf3,Slc9a1,Il12b,Cxcl10,Tlr2,Il18,Ptgs2,Adora2b,Zc3h12a,Tlr3,Tlr9,Il1b,Stard7,Bambi,Hcls1,Jak2,Syk,Ccl12,Bcl2l11,Tnf,Ehd1,Ezr,Rbpms,Mdm2,Il6,Rab21,Micall2,Cdk5r1,Fgr,Sphk1,Il4ra,Ddx58,Plk3,Plagl2 |
| 2.249e-03 | -6.10 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP | 189 | 27 | 15632 | 1249 |
Pde4b,Jarid2,Brwd3,Ppfibp2,Trafd1,Kitl,Grina,Dnajb4,Azi2,Nr4a3,Adrb2,Kif3c,Nqo1,Acvrl1,Stk40,Slc39a4,Traf2,Bcl6,Stat5a,Eif2ak2,Plekha5,Agrn,N4bp1,Cyth3,Trim13,Papss2,Mcoln2 |
| 2.249e-03 | -6.10 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | 189 | 27 | 15632 | 1249 |
St3gal1,Adrb2,Kif3c,Nr4a3,Azi2,Dnajb4,Grina,Glrx,Trafd1,Brwd3,Jarid2,Pde4b,Klf2,Trim21,Mcoln2,Trim13,Cyth3,Slc25a25,Agrn,Plekha5,N4bp1,Spsb1,Eif2ak2,Bcl6,Traf2,Slc39a4,Nqo1 |
| 2.249e-03 | -6.10 | GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN | 189 | 27 | 15632 | 1249 |
Pgk1,Fscn1,Polr2g,Tnip1,Ppp2r1b,Ak4,Mthfd2,Ldha,Wars,Tnfsf14,Lcp2,Eno2,Txn1,Ccl5,Ccne1,Prdx1,Slc16a1,Tpx2,Socs1,Psma6,Dusp4,Phgdh,Psmb9,Eno1,Trip10,Cenpe,Srm |
| 2.249e-03 | -6.10 | GSE29949_CD8_POS_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN | MSigDB lists | GSE29949_CD8_POS_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN | 189 | 27 | 15632 | 1249 |
Tmem123,Prkx,Cxcl1,Ier3,Rcn1,Ifi35,Ppp2r3a,Isg20,Sik3,Asns,Nampt,Gbp2,Mapkbp1,Prnp,Nfkbil1,Slc30a4,Dtnb,Tnfsf8,Cited2,Rbbp8,Mtus1,Itpr1,Ass1,Lrp4,Cst7,Sp140,Klf6 |
| 2.251e-03 | -6.10 | DSPc | smart domains | SM00195 | 35 | 9 | 9567 | 823 |
Dusp8,Dusp5,Dusp14,Dusp2,Dusp6,Dusp4,Dusp16,Dusp1,Dusp28 |
| 2.262e-03 | -6.09 | G-protein alpha-subunit binding | molecular function | GO:0001965 | 35 | 8 | 20217 | 1400 |
Igf1r,Rgs1,Htr2b,Rgs14,Htr2a,Gpsm2,Adrb2,Lpar1 |
| 2.268e-03 | -6.09 | LIU_SOX4_TARGETS_UP | MSigDB lists | LIU_SOX4_TARGETS_UP | 117 | 19 | 15632 | 1249 |
Csf1,Fut8,Isg20,Scn1b,Tbc1d13,Swap70,Plk2,Tmem184b,Thbs1,Tnfsf10,Ppp2r1b,Atp2b4,Enpp4,Vrk2,Usp31,Dusp5,Lif,Mppe1,Zfp281 |
| 2.273e-03 | -6.09 | Ferroptosis | KEGG pathways | mmu04216 | 40 | 10 | 7931 | 713 |
Cp,Acsl5,Gclc,Slc7a11,Hmox1,Prnp,Slc39a14,Gclm,Sat1,Acsl1 |
| 2.273e-03 | -6.09 | Ferroptosis | KEGG pathways | ko04216 | 40 | 10 | 7931 | 713 |
Acsl5,Gclc,Slc7a11,Hmox1,Prnp,Cp,Gclm,Sat1,Acsl1,Slc39a14 |
| 2.283e-03 | -6.08 | Factors involved in megakaryocyte development and platelet production | REACTOME pathways | R-MMU-983231 | 115 | 20 | 8608 | 757 |
Irf2,Irf7,Mafk,Cenpe,Mafg,Kif9,Ehd1,Ifna5,Ifna6,Irf1,Ifna1,Ifna4,Maff,H3f3b,Ifna2,Carmil1,Kif3c,Prkar2b,Jak2,Ifnb1 |
| 2.294e-03 | -6.08 | ENK_UV_RESPONSE_KERATINOCYTE_DN | MSigDB lists | ENK_UV_RESPONSE_KERATINOCYTE_DN | 446 | 53 | 15632 | 1249 |
Mcm6,Slc31a1,Dusp5,Sec24b,Pcdh7,Dek,Flrt2,Ifit1bl2,G3bp2,Nmi,Stxbp3,Malt1,Stau1,Crim1,Myo10,Bcl6,Birc2,Slc2a1,Rbbp8,Abcc5,Tlk2,Mecp2,Ccng2,Cebpd,Tnc,Ifi44,Adrb2,Dyrk2,Stard7,Sema3c,Birc3,Stx6,Eef1e1,Cnn3,Plscr1,Trip13,Trim13,Ccnd2,Tpx2,Gbe1,Rars,Aff1,Klf7,Prpf4,Rnd3,Slc16a1,Fos,Dnaja1,Ifit1bl1,Rapgef5,Cnot4,Cpd,Dusp4 |
| 2.297e-03 | -6.08 | GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_UP | MSigDB lists | GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_UP | 180 | 26 | 15632 | 1249 |
Ifi207,Sphk1,Ifi214,Agtrap,Rnf139,Marcksl1,Bnip3,Mgat1,Ifi209,Ifi205,Timp1,Pik3r5,Casp1,Ifi213,Glrx,Hcls1,Slc43a3,Ifi204,Ifi203,Ifi208,Ifi211,Mndal,Ptch1,Samsn1,Itgal,Fcgr4 |
| 2.297e-03 | -6.08 | GSE27786_CD8_TCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NKCELL_DN | 180 | 26 | 15632 | 1249 |
Sdc4,Nfkbiz,Spata13,Phactr4,Hspa2,Lrp4,Sod2,Gsdmd,Axl,Plac8,Actb,Nfxl1,Trafd1,Oasl1,Ptprj,Rnf19b,Frmd4a,Clec4d,Slc43a3,Plscr1,Inhba,Snx2,Slc4a7,Pik3r6,Gem,Tor1aip1 |
| 2.297e-03 | -6.08 | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_DC_DN | 180 | 26 | 15632 | 1249 |
Rab9,Gpr35,Mmp14,Rhoq,Spry2,Phgdh,Scarf1,Ets2,Cd40,Bmp2,Fcgr1,Gpc1,Tlr6,Arl4a,Irs2,Cyth3,Slc7a5,Scn1b,Ampd3,Tmeff1,Csf3,Osm,Irf8,Plat,Gng4,Max |
| 2.297e-03 | -6.08 | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | MSigDB lists | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | 180 | 26 | 15632 | 1249 |
Whamm,Clcn7,Osbpl3,Socs7,Keap1,Etnk1,Stat1,Dnajb4,Pim1,Acvr1b,Azi2,Stat4,Slc7a8,Pde4b,Daam1,Il15,Slc48a1,Adar,Slc28a2,Bcor,Slc30a1,Tor1aip2,Taf4b,Cers6,Dhx58,Msr1 |
| 2.297e-03 | -6.08 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_UP | 180 | 26 | 15632 | 1249 |
Daam1,Samsn1,Pde4b,Ksr1,Flnb,Il12b,Socs3,Rsbn1,Polr2g,Rap2c,Cd82,Arhgef3,Cited2,Rab32,Cdyl2,Treml2,Nqo1,Ifnb1,Calcrl,Tmtc2,Zfp281,Il4ra,Prdm1,Trp53i11,Batf,Slc48a1 |
| 2.298e-03 | -6.08 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN | 100 | 17 | 15632 | 1249 |
Il18,Fas,Notch1,Col4a2,Cacybp,Ets2,Ifit1bl2,Ifit1bl1,Agrn,Ccnd1,Gadd45g,Cpd,Tmem176a,Tbc1d1,Irgm2,Trim21,Casp3 |
| 2.298e-03 | -6.08 | GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | 100 | 17 | 15632 | 1249 |
Hif1a,Ptgs2,Zc3h12a,Mmp9,Angpt1,Vegfc,Thbs1,Kdr,Jun,Src,Stat5a,Met,Glipr2,Prkce,Edn1,Nrp2,Pdgfb |
| 2.314e-03 | -6.07 | CORDENONSI_YAP_CONSERVED_SIGNATURE | MSigDB lists | CORDENONSI_YAP_CONSERVED_SIGNATURE | 52 | 11 | 15632 | 1249 |
Phgdh,Fscn1,Thbs1,Crim1,Etv5,Mdfic,Dusp1,Gadd45b,Axl,Tspan3,Serpine1 |
| 2.314e-03 | -6.07 | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN | MSigDB lists | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN | 52 | 11 | 15632 | 1249 |
Traf5,Dek,Zhx2,H2-Ab1,Btg2,Mmd,Pou2f2,Birc3,Swap70,Irf8,Cd40 |
| 2.314e-03 | -6.07 | GALE_APL_WITH_FLT3_MUTATED_UP | MSigDB lists | GALE_APL_WITH_FLT3_MUTATED_UP | 52 | 11 | 15632 | 1249 |
Rras2,Phf11a,Chd9,Phf11c,Abcc1,Phf11b,Apobec3,Plagl1,Myo1b,Phf11d,Vps54 |
| 2.314e-03 | -6.07 | BROWNE_HCMV_INFECTION_1HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_1HR_UP | 52 | 11 | 15632 | 1249 |
Pcdh7,Cxcl1,Ldlr,Il6,Mmp14,Igf1r,Atp2b4,Rasgrp1,Nr4a1,Bcl2l11,Gpr18 |
| 2.327e-03 | -6.06 | regulation of collagen metabolic process | biological process | GO:0010712 | 52 | 10 | 20694 | 1406 |
Rgcc,Serpine1,Adora2b,Pdgfrb,Prdx5,Ccl2,Il18,Errfi1,Il6,Pdgfb |
| 2.327e-03 | -6.06 | membrane invagination | biological process | GO:0010324 | 52 | 10 | 20694 | 1406 |
Fcho2,Spire1,Fcgr2b,Xkr8,Rac3,Treml4,Thbs1,Fcgr1,Marco,Msr1 |
| 2.327e-03 | -6.06 | response to extracellular stimulus | biological process | GO:0009991 | 392 | 42 | 20694 | 1406 |
Atf3,Cdkn1a,Adora2b,Casp1,Ldlr,Cpeb4,Adrb2,Nmral1,Asns,Ldha,Noct,Jun,P2ry12,Sod2,Sesn3,Fos,Wdr59,Eif2ak2,Slc25a25,Higd1a,Axl,Clic5,Il1b,Itga4,Gdf15,Gsdmd,Zc3h12a,Mmp9,Zfp36,Sirt1,Slc2a1,Slc16a1,Sell,Cdkn2d,Pim1,Fas,Igf1r,Larp1,Slc39a4,Stat1,Lrp11,Vcam1 |
| 2.336e-03 | -6.06 | LIAO_METASTASIS | MSigDB lists | LIAO_METASTASIS | 467 | 55 | 15632 | 1249 |
Slfn9,Lrp11,Bambi,Ptges,Igf2bp2,Pkp4,Gng4,Uchl1,Smox,Nsmaf,Usp42,H2-Aa,Slc2a6,Ddit4,Tbc1d13,Map4k4,Mthfd1l,Col11a2,Asns,Traf5,Gbp2,Nupr1,Mxd1,Arg2,Agtrap,Slc39a4,B3gnt5,Hdac1,Ddhd1,Slc2a1,Orai2,Socs7,Denr,Mthfd2,Rnf145,Trip13,Nfkbib,Bcorl1,Mmd,Ccne1,Eno2,Sema3c,Zc3hav1,Plagl1,Ctsc,Slfn8,Nqo1,Ifrd1,Vcan,Agrn,Slc7a11,Tmem200b,Gramd1a,Trip10,Hmga1 |
| 2.337e-03 | -6.06 | GSE15659_NAIVE_VS_PTPRC_NEG_CD4_TCELL_DN | MSigDB lists | GSE15659_NAIVE_VS_PTPRC_NEG_CD4_TCELL_DN | 171 | 25 | 15632 | 1249 |
Rnaset2b,Prkx,Spata5l1,Slc43a3,Tdrd7,Rhou,Rnf19a,Wars,Tlr1,Procr,Samsn1,Rnaset2a,Ppm1k,Tnfaip3,Vcpip1,Tpi1,Rbpms,S1pr2,Rab9,Prkce,Ppp2r5a,Top3a,Rhbdf2,Timp1,Trim36 |
| 2.337e-03 | -6.06 | GSE22611_UNSTIM_VS_2H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_UP | MSigDB lists | GSE22611_UNSTIM_VS_2H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_UP | 171 | 25 | 15632 | 1249 |
Acsl1,Ifi204,C3,Mtmr14,Med21,Mndal,Junb,Ifi203,Ifi208,Ifi211,Reps1,Ifi214,F11r,Stxbp1,Ube2e1,Ifi207,Rnf34,Rras2,Ifi205,Dnaja1,Ifi209,Plod3,Ifi213,Psma6,Sdc2 |
| 2.339e-03 | -6.06 | MODULE_317 | MSigDB lists | MODULE_317 | 375 | 46 | 15632 | 1249 |
Stat3,Acvr1,Kdm5b,Gpr68,Plekhf2,Arid5a,Sav1,Mapkbp1,Smg7,Ncoa7,Mcmbp,Itga4,Prdm1,Il1a,Hif1a,Tuba4a,Gja1,Larp1,Ptgs2,Cxcl10,Mmp14,Morc3,Hivep2,Ccl12,Fos,Cited2,Zbtb5,Slamf7,Ddx60,Kat2b,Fpr2,Phip,Trim14,Csf1,Timeless,Ppp4r2,Plekhg1,Lap3,Gem,Clcf1,Chd9,Nfil3,Tnfsf4,Mmp9,Acsl1,Sema4a |
| 2.341e-03 | -6.06 | - | gene3d domains | 1.20.5.120 | 4 | 3 | 8819 | 755 |
Psme2b,Psme2,Psme1 |
| 2.341e-03 | -6.06 | - | gene3d domains | 1.20.120.180 | 4 | 3 | 8819 | 755 |
Psme1,Psme2b,Psme2 |
| 2.354e-03 | -6.05 | mesenchymal cell development | biological process | GO:0014031 | 88 | 14 | 20694 | 1406 |
Notch1,Acvr1,Sema4a,Ednrb,Nrp2,Sema3c,Jag1,Kitl,Hif1a,Sema4c,Htr2b,Edn1,Cited2,Phactr4 |
| 2.355e-03 | -6.05 | EPHD | interpro domains | IPR034732 | 27 | 7 | 19984 | 1430 |
Mllt6,Phf11b,Phf11a,Phf6,Phf11d,Phf11c,Kdm4a |
| 2.358e-03 | -6.05 | RPL22 (ribosomal protein L22) | protein interactions | 6146 | 11 | 5 | 7778 | 753 |
Actb,Ktn1,Flnb,Rrbp1,Ksr1 |
| 2.368e-03 | -6.05 | GO_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | 135 | 21 | 15632 | 1249 |
Pdpn,Psme2,Btg2,Casp2,Mdm2,Ube2e2,Ccnd1,Cnot4,Atm,Ankrd17,Cenpj,Plk2,Pid1,Tnks1bp1,Cdkn1a,Atp2b4,Pml,Psme1,Plk3,Plagl1,Pim1 |
| 2.369e-03 | -6.05 | KOBAYASHI_EGFR_SIGNALING_24HR_DN | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_24HR_DN | 237 | 32 | 15632 | 1249 |
Zc3hav1,Etv5,Tpx2,Sphk1,Cx3cl1,Upp1,Mcm10,Dusp4,Ccnd1,Gpsm2,Srm,Axl,Dcbld2,Ier3,Fam111a,Mcm6,Adora2b,Odc1,Slc43a3,Oasl1,Ell2,Dusp5,Eef1e1,Hat1,Maff,Met,Phlda1,Timeless,Trip13,Dusp6,Psat1,Eno2 |
| 2.372e-03 | -6.04 | - | gene3d domains | 3.40.250.10 | 23 | 7 | 8819 | 755 |
Dusp6,Dusp16,Dusp8,Dusp2,Dusp1,Dusp5,Dusp4 |
| 2.373e-03 | -6.04 | WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D | 614 | 69 | 15632 | 1249 |
Optn,Myc,Prkce,Ikzf1,Irf4,Cited2,Gramd1a,Spsb1,Angpt1,Tle3,Rbl1,Me1,Mark2,Tspo,Ciapin1,St3gal3,Egr1,Tmem176b,Abr,Met,Tmem176a,Plscr1,Alas1,Timeless,Bcorl1,Gbp7,Mov10,Prkar2b,Stard7,Hcls1,Polr2g,Azi2,Acsl1,Dck,Itga5,Uaca,Kif5c,Gbp9,Gbp4,Oaf,Ankrd17,Eno1,Txnrd1,Gypc,Ctu1,Tnfaip3,Gbp2,Mdfic,Cd164,Gys1,St3gal6,Gbp3,Lrch3,Sap30,Atp6v1d,Map2k1,Hopx,Brd2,Hcar2,Acp2,Ptges,Keap1,Rcl1,Dcbld2,Osbpl3,Serpinb9,Nr4a3,Dnaja2,Pcgf5 |
| 2.383e-03 | -6.04 | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP | 153 | 23 | 15632 | 1249 |
Fos,Jun,Cited2,Pde4b,Junb,Dusp1,Casp1,Mmd,Rap1gap2,St3gal5,Ubash3b,Rcsd1,Socs1,Itga4,Nfkbiz,Evl,Socs3,Parp3,Nfil3,Samhd1,Snn,Zc3hav1,Rgs1 |
| 2.386e-03 | -6.04 | Prot_kinase_dom | interpro domains | IPR000719 | 486 | 52 | 19984 | 1430 |
Akt3,Kdr,Mlkl,Prag1,Scyl2,Grk3,Dyrk2,Map3k6,Met,Irak2,Axl,Pim3,Ptk2,Prkx,Acvr1b,Ripk2,Mapkapk2,Trib3,Map2k4,Syk,Ksr1,Sik3,Igf1r,Tlk2,Lyn,Vrk2,Acvr1,Eif2ak2,Mark2,Map3k8,Plk3,Flt1,Map4k4,Src,Pdgfrb,Irak3,Fgr,Pim1,Sgk3,Stk40,Nek6,Ikbke,Acvrl1,Map2k1,Tyk2,Pim2,Hck,Plk2,Prkce,Ripk3,Jak2,Trib1 |
| 2.388e-03 | -6.04 | cytoplasmic side of membrane | cellular component | GO:0098562 | 179 | 23 | 20747 | 1409 |
Gem,Rnf31,Errfi1,Chmp4b,Gng12,Traf5,Pkp4,Gnb4,Rgs1,Src,Fgr,Dst,Gng11,Ezr,Rab21,Gng4,Gna15,Birc2,Gramd1a,Lyn,Traf2,Cyth3,Hck |
| 2.388e-03 | -6.04 | MODULE_66 | MSigDB lists | MODULE_66 | 509 | 59 | 15632 | 1249 |
St3gal5,Htra1,Ppp4r2,Bcl9,Fabp7,Lmo4,Rims3,Ednrb,Eno2,Dnajb2,Cdkn1a,Lhx2,Rgs1,Acsl1,Cacnb3,C3,Rac3,Kif5c,Gadd45g,Dtnb,Psd,Vcan,Fos,Cx3cr1,Ifit1bl1,Nr4a1,Angpt1,Rnd3,Ccnd2,Stxbp1,Stoml1,Phlda1,Scn1b,Atp6v1d,Cnp,Gja1,Ifit1bl2,Pde4b,Gng12,Inpp1,Rsbn1,Hmox1,Rtn1,Dusp5,Gng4,Uchl1,Hspa2,Dusp8,D1Ertd622e,Tnc,Mtus1,Itpr1,Abcc5,Tnf,Myo10,Rnd1,Stat2,Nupr1,Mthfr |
| 2.400e-03 | -6.03 | regulation of actin filament length | biological process | GO:0030832 | 179 | 23 | 20694 | 1406 |
Dbnl,Carmil1,Tmsb10,Rictor,Myadm,Prkce,Spire1,Tlr2,Icam1,Swap70,Rac3,Cyfip1,Fchsd2,Vasp,Tmod3,Nck1,Evl,Whamm,Cdc42ep2,Cdc42ep4,Plek,Csf3,Hcls1 |
| 2.402e-03 | -6.03 | Nos2 (nitric oxide synthase 2, inducible) | protein interactions | 18126 | 7 | 4 | 7778 | 753 |
Nfkb1,Ptgs2,Rel,Nos2 |
| 2.402e-03 | -6.03 | Bach2 (BTB and CNC homology, basic leucine zipper transcription factor 2) | protein interactions | 12014 | 7 | 4 | 7778 | 753 |
Prdm1,Bcl6,Mafk,Mafg |
| 2.402e-03 | -6.03 | Irf4 (interferon regulatory factor 4) | protein interactions | 16364 | 7 | 4 | 7778 | 753 |
Irf8,Ripk2,Myd88,Stat3 |
| 2.402e-03 | -6.03 | Hnrnpa0 (heterogeneous nuclear ribonucleoprotein A0) | protein interactions | 77134 | 7 | 4 | 7778 | 753 |
Cxcl2,Tnf,Mapkapk2,Ptgs2 |
| 2.403e-03 | -6.03 | MODULE_79 | MSigDB lists | MODULE_79 | 92 | 16 | 15632 | 1249 |
Ccnd2,Fpr1,Ier3,Mmp9,Gbp2,Vcam1,Thbs1,Fcgr1,Cd14,Timp1,Pdgfrb,Ccr1,Ccl12,Ccl5,Cebpd,Kctd12 |
| 2.403e-03 | -6.03 | GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | 92 | 16 | 15632 | 1249 |
Src,Gdf15,Ltbp2,Ccl12,Fos,Zyx,Jun,Fut8,Pdgfb,Acvr1,Acvrl1,Ptk2,Pml,F11r,Gcnt2,Bambi |
| 2.405e-03 | -6.03 | regulation of phosphatase activity | biological process | GO:0010921 | 158 | 21 | 20694 | 1406 |
Ppp1r14b,Plek,Ppp1r15a,Pdgfrb,Rcan1,Ppp4r2,Ppp2r2a,Ppp2r3a,Marf1,Bmp2,Ppp1r15b,Phactr4,Spred1,Ppp2r1b,Vcan,Jak2,Ppp6r1,Ppp2r5a,Ripk3,Ahr,Tnf |
| 2.407e-03 | -6.03 | TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | REACTOME pathways | R-MMU-6804115 | 17 | 6 | 8608 | 757 |
Cenpj,Cnot4,Plk3,Btg2,Tnks1bp1,Plk2 |
| 2.412e-03 | -6.03 | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_17_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_17_PRODUCTION | 13 | 5 | 15632 | 1249 |
Myd88,Il15,Nod2,Il12b,Il18 |
| 2.412e-03 | -6.03 | MATZUK_EARLY_ANTRAL_FOLLICLE | MSigDB lists | MATZUK_EARLY_ANTRAL_FOLLICLE | 13 | 5 | 15632 | 1249 |
Thbs1,Src,Ahr,Taf4b,Ccnd2 |
| 2.412e-03 | -6.03 | REACTOME_REGULATION_OF_IFNG_SIGNALING | MSigDB lists | REACTOME_REGULATION_OF_IFNG_SIGNALING | 13 | 5 | 15632 | 1249 |
Socs1,Ptpn2,Jak2,Stat1,Socs3 |
| 2.412e-03 | -6.03 | ONGUSAHA_BRCA1_TARGETS_UP | MSigDB lists | ONGUSAHA_BRCA1_TARGETS_UP | 13 | 5 | 15632 | 1249 |
Mmp13,Tgfbi,Ddit4,Hmox1,Col18a1 |
| 2.412e-03 | -6.03 | WACKER_HYPOXIA_TARGETS_OF_VHL | MSigDB lists | WACKER_HYPOXIA_TARGETS_OF_VHL | 13 | 5 | 15632 | 1249 |
Hk2,Ccnd1,P4ha1,Cp,Eno2 |
| 2.412e-03 | -6.03 | HOLLERN_MICROACINAR_BREAST_TUMOR_DN | MSigDB lists | HOLLERN_MICROACINAR_BREAST_TUMOR_DN | 13 | 5 | 15632 | 1249 |
Tnc,Dram1,Slc16a1,Tnfaip2,Ptges |
| 2.412e-03 | -6.03 | GO_NEGATIVE_REGULATION_OF_MYELOID_CELL_APOPTOTIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MYELOID_CELL_APOPTOTIC_PROCESS | 13 | 5 | 15632 | 1249 |
Ccl5,Kitl,Irf7,Nod2,Clec5a |
| 2.412e-03 | -6.03 | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP | MSigDB lists | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP | 13 | 5 | 15632 | 1249 |
Spsb1,Ampd3,Tnip1,Ltbp2,Plaur |
| 2.412e-03 | -6.03 | MODULE_501 | MSigDB lists | MODULE_501 | 13 | 5 | 15632 | 1249 |
Mmp14,Dusp2,Casp1,Bst1,Sema3c |
| 2.415e-03 | -6.03 | protease binding | molecular function | GO:0002020 | 145 | 20 | 20217 | 1400 |
Sell,Prnp,Ldlr,Serpinb9,Hspa1a,Cflar,Lcn2,Casp3,Timp1,Fas,Ripk2,Serpine1,Rffl,Tnf,Rnf139,Tnfaip3,Malt1,Bfar,Itgav,Cdk5r1 |
| 2.427e-03 | -6.02 | GSE3039_CD4_TCELL_VS_B1_BCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_B1_BCELL_UP | 190 | 27 | 15632 | 1249 |
Ciapin1,Cd74,Kmo,Palld,Stxbp1,Ifit1,Ciita,Cd34,Pim3,Trp53i11,Gys1,Zyx,Ccnd1,Dbnl,Ms4a6d,Uaca,Rtn1,Oasl1,Pf4,Frmd6,Jak2,Myadm,Slamf9,Cd69,H2-Aa,St3gal5,Flnb |
| 2.427e-03 | -6.02 | regulation of heat generation | biological process | GO:0031650 | 15 | 5 | 20694 | 1406 |
Il1b,Tnf,Ednrb,Ccl5,Ptgs2 |
| 2.427e-03 | -6.02 | negative regulation of anoikis | biological process | GO:2000811 | 15 | 5 | 20694 | 1406 |
Ptk2,Cav1,Itga5,Notch1,Src |
| 2.427e-03 | -6.02 | regulation of skeletal muscle cell proliferation | biological process | GO:0014857 | 15 | 5 | 20694 | 1406 |
Angpt1,Stat3,Sirt1,Jak2,Cflar |
| 2.427e-03 | -6.02 | alpha-beta T cell lineage commitment | biological process | GO:0002363 | 15 | 5 | 20694 | 1406 |
Irf4,Stat3,Batf,Il6,Spn |
| 2.427e-03 | -6.02 | negative regulation of inflammatory response to antigenic stimulus | biological process | GO:0002862 | 15 | 5 | 20694 | 1406 |
Fcgr2b,Il12b,Spn,Il10,Nod2 |
| 2.427e-03 | -6.02 | modulation by symbiont of host cellular process | biological process | GO:0044068 | 15 | 5 | 20694 | 1406 |
Irgm2,Tnip1,Irgm1,Serpinb9,Bcl2l11 |
| 2.427e-03 | -6.02 | toll-like receptor 4 signaling pathway | biological process | GO:0034142 | 15 | 5 | 20694 | 1406 |
Ripk2,Nfkbia,Prkce,Cd14,Tnip3 |
| 2.428e-03 | -6.02 | REACTOME_SIGNAL_AMPLIFICATION | MSigDB lists | REACTOME_SIGNAL_AMPLIFICATION | 31 | 8 | 15632 | 1249 |
Gng11,Gng4,Src,Gnb4,Pla2g4a,Gna15,Gng12,P2ry12 |
| 2.428e-03 | -6.02 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 31 | 8 | 15632 | 1249 |
Nod1,Zc3hav1,Dhx58,Ddx60,Ripk2,Cd180,Il12b,Ankrd17 |
| 2.428e-03 | -6.02 | GO_CELLULAR_RESPONSE_TO_HEAT | MSigDB lists | GO_CELLULAR_RESPONSE_TO_HEAT | 31 | 8 | 15632 | 1249 |
Tfec,Cdkn1a,Thbs1,Hspa1a,Cxcl10,Lyn,Il1a,Hmox1 |
| 2.428e-03 | -6.02 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS | 31 | 8 | 15632 | 1249 |
Sirt1,Met,Hif1a,Nr4a3,Txn1,Hp,Hsph1,Sod2 |
| 2.428e-03 | -6.02 | GO_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 31 | 8 | 15632 | 1249 |
Hp,Hsph1,Tnf,Txn1,Sesn3,Gch1,Met,Nr4a3 |
| 2.428e-03 | -6.02 | vasodilation | biological process | GO:0042311 | 36 | 8 | 20694 | 1406 |
Adrb2,Plod3,Ednrb,Sod2,Adora2b,Adora2a,Tnf,Gch1 |
| 2.428e-03 | -6.02 | tumor necrosis factor-mediated signaling pathway | biological process | GO:0033209 | 36 | 8 | 20694 | 1406 |
Stat1,Traf2,Jak2,Tnfrsf1b,Nfkbia,Fas,Aim2,Tnf |
| 2.428e-03 | -6.02 | positive regulation of epithelial cell apoptotic process | biological process | GO:1904037 | 36 | 8 | 20694 | 1406 |
Cd40,Hdac1,Thbs1,Itga4,Jak2,Col18a1,Rgcc,Ccl12 |
| 2.433e-03 | -6.02 | Regulation of IFNG signaling | REACTOME pathways | R-MMU-877312 | 12 | 5 | 8608 | 757 |
Stat1,Socs1,Socs3,Jak2,Ptpn2 |
| 2.441e-03 | -6.02 | TIR | smart domains | SM00255 | 23 | 7 | 9567 | 823 |
Tlr1,Il18rap,Tlr6,Tlr2,Tlr9,Tlr3,Myd88 |
| 2.441e-03 | -6.02 | RHOD | smart domains | SM00450 | 23 | 7 | 9567 | 823 |
Dusp4,Dusp1,Dusp16,Dusp6,Dusp2,Dusp8,Dusp5 |
| 2.444e-03 | -6.01 | positive regulation of organelle assembly | biological process | GO:1902117 | 79 | 13 | 20694 | 1406 |
Edn1,G3bp2,Dync1h1,Cenpj,Tmem67,Tnf,Sdc1,Fscn1,Palld,Src,Hap1,Gpsm2,Sdc4 |
| 2.449e-03 | -6.01 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | molecular function | GO:0016814 | 28 | 7 | 20217 | 1400 |
Gch1,Apobec3,Ampd3,Gda,Mthfd2,Adar,Zbp1 |
| 2.454e-03 | -6.01 | protein localization | biological process | GO:0008104 | 1903 | 160 | 20694 | 1406 |
Pikfyve,Pml,Cdkn1a,Etv5,Katna1,Arl5c,Ift57,Ikzf1,Serp1,Angpt1,Rab20,Rtn2,Fcho2,Rffl,Daxx,Snx2,Tnf,Atp6v1d,Syk,Ric1,Sh3bp4,Egr2,Stxbp1,Cd74,Parp3,Tnfaip2,Slc28a2,Txn1,Traf3ip2,Il1rn,Agrn,Ift22,Tbc1d1,Plod3,Bcl6,Ppp1r15a,Tor1aip2,Calcrl,Notch2,Hk1,Rabgef1,Srgn,Rab10,Nlgn2,Arl5b,Dennd2a,Msr1,Stxbp3,Phip,Rrbp1,Cacnb3,Grk3,Rapgef2,Rab9,Plek,Trem1,Mcm9,Syne2,Cox18,Mid1,Kpna3,Ap3m2,Pgap2,Lgals9,Hhex,Isg15,Tap1,Arf4,Mdm2,Cav1,Lyn,Slc15a3,Psmd10,Spire1,Keap1,Myadm,Parp11,Rab32,Tbc1d13,Hk2,Sqstm1,Pdzd11,F11r,Rtp4,Ptch1,Itgav,Ezr,Rab21,D1Ertd622e,Hinfp,Arrdc4,Nfkbia,Gbp2,Ehd1,Tspo,Fchsd2,Rab11fip1,Ap3b1,Aim2,Tulp3,Abcb1a,Mcoln2,Mecp2,Kif5c,Cenpe,Morc3,Rnf19b,Rab3ip,Clic5,Htr2a,Dtx3l,Itga4,Svbp,Vps54,Dcp1a,Nod2,Tmsb10,Frmd6,Tap2,Dennd1b,Dnaja1,Stau1,Tor1aip1,Homer1,Stx6,Snx10,Hap1,Stx11,Rrs1,Sec24a,Nxf1,Treml4,Myo1b,Stat3,Aftph,Lrp4,Nos2,Rhbdf2,Arl4a,Rilpl1,Plekhf2,Nlrp3,Notch1,Chmp4b,Ranbp2,Pou2f2,Tomm70a,Optn,Apba1,Itgal,Tnfaip3,Tlr2,Fam53c,Mpp7,Adar,Rab19,Nfkbib,Nlrc4,Tlr6,Lcp2 |
| 2.456e-03 | -6.01 | immunoglobulin production | biological process | GO:0002377 | 61 | 11 | 20694 | 1406 |
Nod2,Samhd1,Traf3ip2,Fas,Atm,Pou2f2,H2-Ab1,Swap70,Batf,Fgl2,Icosl |
| 2.456e-03 | -6.01 | IL-1_fam | interpro domains | IPR000975 | 9 | 4 | 19984 | 1430 |
Il1b,Il18,Il1a,Il1rn |
| 2.460e-03 | -6.01 | FAELT_B_CLL_WITH_VH3_21_DN | MSigDB lists | FAELT_B_CLL_WITH_VH3_21_DN | 45 | 10 | 15632 | 1249 |
Ccng2,Tspo,Spen,Fcgr2b,Plcl2,Serp1,Lmo4,Tab2,Psmd10,Smc5 |
| 2.460e-03 | -6.01 | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | 45 | 10 | 15632 | 1249 |
Nod2,Hcls1,Kitl,Hif1a,Cd74,Irf7,Bcl6,Irs2,Axl,Ccl5 |
| 2.465e-03 | -6.01 | GO_REGULATION_OF_TISSUE_REMODELING | MSigDB lists | GO_REGULATION_OF_TISSUE_REMODELING | 60 | 12 | 15632 | 1249 |
Syk,Gja1,Src,Il12b,Il18,Ubash3b,Pml,Ptger4,Abr,Tnfaip3,Cd38,Il15 |
| 2.465e-03 | -6.01 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN | 60 | 12 | 15632 | 1249 |
B3gnt5,Lipg,Pdgfb,Fam102b,Arl4a,Ifit3b,Ifit3,Stat1,Rapgef5,Ifit1bl2,Ifit1bl1,Shisa3 |
| 2.478e-03 | -6.00 | MODULE_459 | MSigDB lists | MODULE_459 | 366 | 45 | 15632 | 1249 |
Trim14,Csf1,Ppp4r2,Timeless,Plekhg1,Lap3,Gem,Clcf1,Chd9,Nfil3,Mmp9,Acsl1,Sema4a,Mmp14,Morc3,Hivep2,Ccl12,Fos,Cited2,Zbtb5,Slamf7,Ddx60,Kat2b,Phip,Fpr2,Gja1,Tuba4a,Larp1,Ptgs2,Cxcl10,Stat3,Kdm5b,Acvr1,Gpr68,Plekhf2,Arid5a,Mapkbp1,Sav1,Smg7,Ncoa7,Mcmbp,Itga4,Prdm1,Hif1a,Il1a |
| 2.484e-03 | -6.00 | GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_DN | MSigDB lists | GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_DN | 181 | 26 | 15632 | 1249 |
Homer1,Eno1,Cenpe,Src,Srm,Txnrd1,Cd164,Me1,Myo1b,Rabgef1,Dusp6,Dcun1d3,Rnf19a,Inhba,Snx2,Fzd1,Met,Pde7b,Clec5a,Mcm6,Dio2,Plaur,Il1b,Nfil3,Il1rn,Ccl4 |
| 2.484e-03 | -6.00 | GSE27786_LIN_NEG_VS_NKTCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_NKTCELL_DN | 181 | 26 | 15632 | 1249 |
Tap1,Ccdc88b,Pttg1,Nck1,Usp25,Parp9,Gadd45g,Sat1,Rgs14,Arid5a,Itgav,Whamm,Tnfsf10,Tnip1,Hcls1,Ikbke,Atp10a,Ifi35,Etnk1,Il13ra1,Slc39a14,Kctd12,Cysltr2,Nmi,Irf7,Jarid2 |
| 2.484e-03 | -6.00 | GSE3982_MAC_VS_TH1_DN | MSigDB lists | GSE3982_MAC_VS_TH1_DN | 181 | 26 | 15632 | 1249 |
Kif5c,Pim2,Ifi35,Pdk3,Dmwd,Fubp1,Tap2,Cav1,Samsn1,Il10,Timeless,Slc7a5,Nfkbib,Isg20,Dgka,Stoml1,Bcor,Ier2,Traf5,Crlf3,Angpt1,Prpf4,Cnn2,Ezr,Hspa2,Tlk2 |
| 2.484e-03 | -6.00 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN | 181 | 26 | 15632 | 1249 |
Lztfl1,Ctsc,Tcf4,Otud1,Agrn,Adar,Gnb4,Aldh1b1,Gbe1,Ppm1l,Mpp7,Trim13,Ube2e2,Bcl9,Cnn3,Ascc3,Brwd3,Map4k4,Arid4a,Snn,Plaur,Dr1,Uchl1,Smc5,Egr3,Kpna3 |
| 2.484e-03 | -6.00 | GO_PEPTIDYL_TYROSINE_MODIFICATION | MSigDB lists | GO_PEPTIDYL_TYROSINE_MODIFICATION | 181 | 26 | 15632 | 1249 |
Pdgfb,Tyk2,Met,Il12rb1,Osm,Pdgfrb,Map2k1,Kdr,Jak2,Igf1r,Dyrk2,Ripk2,Ptk2,Map2k4,Lyn,Syk,Flt1,Eif2ak2,Stat5a,Axl,Src,Tpst1,Il15,Hck,Lif,Fgr |
| 2.484e-03 | -6.00 | GSE17580_TREG_VS_TEFF_UP | MSigDB lists | GSE17580_TREG_VS_TEFF_UP | 181 | 26 | 15632 | 1249 |
Mdn1,Phlpp1,Cyfip1,Sla,Hif1a,Zfp281,Upp1,Tlr1,Ccdc25,Il12rb1,Tnfrsf1b,Casp8,Ptch1,Gbp7,Vps54,Samsn1,Lad1,Asns,Sh3bgrl2,Gfi1,Abcc1,Socs3,Ttc39b,Kcna3,Pim1,Rcn1 |
| 2.485e-03 | -6.00 | GO_TISSUE_REMODELING | MSigDB lists | GO_TISSUE_REMODELING | 84 | 15 | 15632 | 1249 |
Notch2,Lif,Adrb2,Hif1a,Il1a,Mmp14,Il6,Acvrl1,Jag1,Mdm2,Gja1,Src,Axl,Sema3c,Cav1 |
| 2.486e-03 | -6.00 | regulation of synapse organization | biological process | GO:0050807 | 267 | 31 | 20694 | 1406 |
Sema4a,Il10,Adgrl2,Fcgr2b,Etv5,Nrp2,Prnp,Fzd1,Lrp4,Tnf,Cyfip1,Mecp2,Ptk2,Chmp4b,Agrn,Arf4,Flrt2,Slc7a11,Igsf9,Cdk5r1,Tlr2,Lrp8,Srgn,Crkl,Nlgn2,Dbnl,Homer1,Rims3,Sipa1l1,Flrt3,Ntng2 |
| 2.507e-03 | -5.99 | MHC_I-like_Ag-recog_sf | interpro domains | IPR037055 | 50 | 10 | 19984 | 1430 |
H60b,H2-T10,Procr,H2-Q6,H2-Q4,H2-Q7,H2-M2,H2-T24,Raet1e,H2-T22 |
| 2.511e-03 | -5.99 | muscle tissue development | biological process | GO:0060537 | 347 | 38 | 20694 | 1406 |
Flnb,Ifrd1,Homer1,Cav1,Maff,Nupr1,Ahr,Egr1,Csrp1,Btg2,Tiparp,Sgcb,Myc,Pdgfrb,Rcan1,Notch1,Hivep3,Kdm6b,Cacybp,Cited2,Egr2,Fos,Sap30,Cflar,Bcl9,Hlx,Plagl1,Psma6,Sema3c,Slc9a1,Angpt1,Met,Casp8,Atf3,Map2k4,Nr4a1,Acvr1,Bmp2 |
| 2.518e-03 | -5.98 | IL1 | pfam domains | PF00340 | 9 | 4 | 18711 | 1348 |
Il1b,Il1rn,Il18,Il1a |
| 2.518e-03 | -5.98 | GO_SPLEEN_DEVELOPMENT | MSigDB lists | GO_SPLEEN_DEVELOPMENT | 38 | 9 | 15632 | 1249 |
Nfkb2,Pbx1,Ripk3,Bcl2l11,Fas,Jarid2,Cited2,Psmb9,Tet2 |
| 2.518e-03 | -5.98 | WARTERS_IR_RESPONSE_5GY | MSigDB lists | WARTERS_IR_RESPONSE_5GY | 38 | 9 | 15632 | 1249 |
Gdf15,Fas,Atf3,Plk3,Cdkn1a,Mdm2,Notch1,Btg2,Plcl2 |
| 2.528e-03 | -5.98 | Rap1 signaling pathway | KEGG pathways | ko04015 | 213 | 32 | 7931 | 713 |
Flt1,Ralgds,Pdgfc,Igf1r,Kitl,Vegfc,Pdgfrb,Fpr1,Rac3,Lcp2,Adora2a,Crkl,Met,Map2k1,Dock4,Lpar1,Csf1,Itgal,Akt3,Src,Pdgfb,Angpt1,Rapgef5,Thbs1,Kdr,Sipa1l1,Actb,Rapgef2,Pik3cd,Adora2b,Vasp,Rgs14 |
| 2.528e-03 | -5.98 | Rap1 signaling pathway | KEGG pathways | mmu04015 | 213 | 32 | 7931 | 713 |
Kitl,Flt1,Ralgds,Igf1r,Pdgfc,Map2k1,Dock4,Met,Lpar1,Csf1,Rac3,Lcp2,Vegfc,Fpr1,Pdgfrb,Crkl,Adora2a,Thbs1,Akt3,Src,Itgal,Rapgef5,Pdgfb,Angpt1,Pik3cd,Adora2b,Rapgef2,Vasp,Rgs14,Kdr,Actb,Sipa1l1 |
| 2.532e-03 | -5.98 | GO_INTEGRIN_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_INTEGRIN_MEDIATED_SIGNALING_PATHWAY | 76 | 14 | 15632 | 1249 |
Fgr,Itga9,Itga5,Ptk2,Itga4,Hck,Zyx,Itgal,Syk,Itgav,Plek,Src,Itgb8,Fut8 |
| 2.532e-03 | -5.98 | MUNSHI_MULTIPLE_MYELOMA_UP | MSigDB lists | MUNSHI_MULTIPLE_MYELOMA_UP | 76 | 14 | 15632 | 1249 |
Cflar,Hcls1,Angpt1,Relb,Pim2,Isg20,Csf1,Psme2,Acvrl1,Axl,Eif4g2,Nfkbia,Fos,Jun |
| 2.532e-03 | -5.98 | CLEC7A/inflammasome pathway | REACTOME pathways | R-MMU-5660668 | 4 | 3 | 8608 | 757 |
Malt1,Casp8,Il1b |
| 2.532e-03 | -5.98 | Neurophilin interactions with VEGF and VEGFR | REACTOME pathways | R-MMU-194306 | 4 | 3 | 8608 | 757 |
Nrp2,Kdr,Flt1 |
| 2.533e-03 | -5.98 | GSE12366_GC_VS_MEMORY_BCELL_DN | MSigDB lists | GSE12366_GC_VS_MEMORY_BCELL_DN | 172 | 25 | 15632 | 1249 |
Rnf19a,Parp12,Dgka,Pde4b,Klf2,Fosb,Pdgfrb,Cflar,Notch2,Ust,Cdkn1a,Snn,Cd55,Egr3,Fndc3a,Stat1,Phyh,Mob3b,Stard5,Il18bp,Dock10,Dusp1,Slc2a1,Oas3,Ccnd2 |
| 2.533e-03 | -5.98 | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP | 172 | 25 | 15632 | 1249 |
Ppfibp1,Hk3,Sla,Pilrb2,Nxf1,P2ry14,Il4ra,Kmo,Evl,Treml2,Phlpp1,Tbc1d1,Bcl6,Tpst1,Cd40,Pilrb1,Rab20,Itga5,Bst1,Mmd,Zfp324,Icosl,Tnfsf14,4930523C07Rik,Junb |
| 2.560e-03 | -5.97 | TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D | MSigDB lists | TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D | 438 | 52 | 15632 | 1249 |
Akt3,Sirt1,Etv6,Rabgef1,Abtb2,Chd9,Egr3,Cpeb4,Sema4c,Rnf145,Acsl1,Prkce,Mmp14,Cpd,Bcl2l11,Fos,Slc25a25,Aff1,Palld,Kat2b,Trim13,Irs2,Phlda1,G3bp2,Ccnj,Cdyl,Map2k1,Plcl2,Rsbn1,Osbpl3,Fmnl2,Igf2bp2,Snn,Dusp5,Fndc3a,Usp42,Tgfbi,Nsmaf,Spire1,Nr4a3,Nr3c1,Tbc1d1,Itgb8,Mecp2,Zfp800,Dock10,Slc25a37,Klf6,Rnf34,Crim1,Lif,Il1a |
| 2.560e-03 | -5.97 | Small_GTP-bd_dom | interpro domains | IPR005225 | 161 | 22 | 19984 | 1430 |
Rhoq,Arf4,Arl4a,Rhoc,Gem,Rap2c,Rab19,Arl5c,Rnd1,Rhoh,Rab20,Rnd3,Rras2,Nkiras1,Rhof,Rab32,Rac3,Arl5b,Rab9,Rhou,Rab10,Rab21 |
| 2.571e-03 | -5.96 | regulation of organ growth | biological process | GO:0046620 | 118 | 17 | 20694 | 1406 |
Bcl2l11,Serp1,Sirt1,Tomm70a,Nr3c1,Sav1,Notch1,Trip10,Ptk2,Jarid2,Gja1,Edn1,Dusp6,Cited2,Pim1,Ahr,Hlx |
| 2.580e-03 | -5.96 | regulation of reproductive process | biological process | GO:2000241 | 180 | 23 | 20694 | 1406 |
Osm,Inhba,Il1a,P2ry2,Nupr1,Trip13,Ptger4,Cited2,Igf1r,Lif,Abcb1a,Plat,Ptafr,Acvr1b,Stxbp1,Timp1,Notch1,Prdm9,Pde5a,Src,Plau,Il18,Ednrb |
| 2.580e-03 | -5.96 | alpha-amino acid metabolic process | biological process | GO:1901605 | 180 | 23 | 20694 | 1406 |
Adhfe1,Plod3,Gclm,P4ha1,Tha1,Txnrd1,Plod2,Kmo,Gclc,Hdc,Ero1l,Mecp2,P4ha2,Mthfr,Gfpt1,Arg2,Egln3,Nos2,Phgdh,Asns,Psat1,Odc1,Ass1 |
| 2.583e-03 | -5.96 | negative regulation of neurogenesis | biological process | GO:0050768 | 336 | 37 | 20694 | 1406 |
Stap1,Sema4c,Rap1gap2,Ifrd1,Pbx1,Cdk5r1,Fas,Cav1,Zhx2,Kremen1,Ednrb,Mdm2,Il1b,Prag1,Notch1,Hmga2,Il15ra,Gfi1,Dync1i2,Ptk2,Casz1,Mecp2,Kdm4a,Jag1,Tspo,Lpar1,Lrp4,Stat3,Lhx2,Plk2,Map4k4,Rapgef2,Cd38,Sema3c,Ldlr,Katna1,Sema4a |
| 2.595e-03 | -5.95 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | 136 | 21 | 15632 | 1249 |
Nupr1,Adrb2,Papss2,Trib3,Tspo,Clic4,Gpc1,Cd34,Rbms2,Col4a2,Acp2,Abcc1,Csrp1,Agrn,Dusp1,Plac8,Snx10,Sema3c,Klf2,Asns,Carhsp1 |
| 2.595e-03 | -5.95 | MODULE_111 | MSigDB lists | MODULE_111 | 136 | 21 | 15632 | 1249 |
Scn1b,Fcgr2b,Oas2,Stat4,Smpdl3b,Psd,Ccl12,Rapgef5,Flt1,Pbx1,Ikbke,Cd34,Il1rn,Gng4,Apba1,Stxbp1,Lif,Fgr,Il2rg,Il4ra,Acvr1b |
| 2.596e-03 | -5.95 | GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 154 | 23 | 15632 | 1249 |
Tmem229b,Phf11d,Fam111a,Fpr1,Psmb8,Adap2,Pdgfb,Ube2l6,Nmi,Slpi,Hap1,Met,Hhex,Nr1h3,Nod1,Phf11a,Phf11c,Ifit2,Phf11b,Mgat1,Pla2g4a,Ccnd1,Tapbp |
| 2.596e-03 | -5.95 | GSE32901_TH17_EMRICHED_VS_TH17_NEG_CD4_TCELL_DN | MSigDB lists | GSE32901_TH17_EMRICHED_VS_TH17_NEG_CD4_TCELL_DN | 154 | 23 | 15632 | 1249 |
Parp11,Hcls1,Ppp2r2a,Nfkb1,Abtb2,Plk2,Zfp36,Nfkbiz,Traf1,Rtp4,Ifih1,Hif1a,Spata13,Pde3b,Sla,Tnfaip3,Ppfibp1,Abcc5,Nfkbia,Bcl6,Otud1,Aftph,Kcnj2 |
| 2.596e-03 | -5.95 | GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_UP | MSigDB lists | GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_UP | 154 | 23 | 15632 | 1249 |
Mndal,Ifi208,Tlr1,Slpi,Ifi211,Ifi203,Ifi204,Slfn9,Prkx,Apobec3,Ifi213,Ifi209,Ifi205,Slfn8,Nqo1,Dhx58,Lrp8,Ifi214,Fbxo4,Mapkbp1,Sav1,Ifi207,Pdgfc |
| 2.598e-03 | -5.95 | response to temperature stimulus | biological process | GO:0009266 | 159 | 21 | 20694 | 1406 |
Gclc,Tfec,Dio2,Ccl2,Hspa1b,Htr2a,Adrb2,Pde4b,Plac8,Dnaja2,Daxx,Hmox1,Il1a,Osm,Lrp11,Htr2b,Hspa1a,Rnf34,Dnaja1,Psip1,Hspa2 |
| 2.598e-03 | -5.95 | regulation of actin filament polymerization | biological process | GO:0030833 | 159 | 21 | 20694 | 1406 |
Myadm,Tmod3,Icam1,Spire1,Prkce,Tlr2,Tmsb10,Carmil1,Vasp,Fchsd2,Rictor,Dbnl,Cyfip1,Hcls1,Rac3,Whamm,Csf3,Cdc42ep2,Cdc42ep4,Nck1,Evl |
| 2.605e-03 | -5.95 | GSE21033_3H_VS_24H_POLYIC_STIM_DC_UP | MSigDB lists | GSE21033_3H_VS_24H_POLYIC_STIM_DC_UP | 145 | 22 | 15632 | 1249 |
Pfkfb3,Myo10,Tab2,Gbp3,Aftph,Rnf24,Arhgap26,Pik3r5,Itpr1,Rgs14,Otud1,Tmem184b,Tnip1,Ppfibp2,Fmnl2,Gfi1,Parp3,Map3k8,Rcsd1,Zfp36,Lnpep,Lcp2 |
| 2.617e-03 | -5.95 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP | 191 | 27 | 15632 | 1249 |
Nr4a3,Parp3,Gfi1,Inpp1,Osbpl3,Hopx,Ahrr,Ankib1,Il12rb1,Inpp5b,Cysltr2,Slc9a1,Il4ra,Malt1,Slc28a2,Cd38,Homer1,Acpp,Ppp6r1,Abcc5,Crbn,Pde5a,Samd9l,Cd200r4,Setdb2,Gbp9,Gbp4 |
| 2.617e-03 | -5.95 | GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_UP | 191 | 27 | 15632 | 1249 |
Klf7,Angpt1,Rras2,Sav1,Fam133b,Kmo,Arl4a,Il4ra,Mapkapk2,Mdm2,Acvrl1,Fut8,Ppfibp2,Cdkn1a,Cacna1d,Cd82,Gcnt2,Tmem123,Pim1,Mafg,St7,Il13ra1,Wars,Hk2,Ksr1,Tmeff1,Serpine1 |
| 2.640e-03 | -5.94 | macromolecule catabolic process | biological process | GO:0009057 | 823 | 77 | 20694 | 1406 |
Pnpt1,Rffl,Magohb,Rnf34,Znrf3,Usp42,Ago3,Uba7,Armc8,Psmb8,Pml,Casp8,Klhl25,Noct,Bfar,Arrdc4,Dcp2,Gtpbp2,Rnf19a,Psmb9,Uchl1,Zhx2,Dnajb2,Xrn1,Tmem67,Birc2,Tent2,Cnot4,Cop1,Rnf19b,Dcp1a,Lnpep,Zfp36,Psmb10,Bnip3,Dtx3l,Psmb6,Oas2,Psma6,Rnf14,Gpc1,Ankib1,Traf2,Usp12,Atm,Tent4a,Usp25,Ctsc,Smg7,Ldlr,Rnaset2a,Aoah,Isg20,Ubr4,Peli1,Fbxo4,Slfn8,Ube2l6,Tut7,Keap1,Tnfaip3,Cemip2,Crbn,Usp18,Znrf1,Helz2,Chmp4b,Isg15,Trim13,Polr2g,Zc3h12a,Spsb1,Rnf139,Sirt1,Mdm2,Arel1,Dnase1l3 |
| 2.641e-03 | -5.94 | Osteoclast | WikiPathways | WP454 | 14 | 6 | 4813 | 540 |
Acp5,Ifnb1,Slc9a1,Gpr68,Pdgfb,Ifnar1 |
| 2.645e-03 | -5.94 | CATTTCA_MIR203 | MSigDB lists | CATTTCA_MIR203 | 258 | 34 | 15632 | 1249 |
Tnfrsf8,Sgk3,Rnf34,Ahr,Egr1,Irs2,Kmo,Tmtc2,Zfp281,Edn1,D1Ertd622e,Vcan,Mafk,Mecp2,Src,Ets2,Cited2,Dr1,Rpgrip1l,Fmnl2,Socs3,Ell2,Dusp5,Cpeb4,Naa25,Egr3,Gpr85,Spire1,Nr4a3,Rab10,Spen,Tshz1,Dcun1d3,Atm |
| 2.649e-03 | -5.93 | TTTTGAG_MIR373 | MSigDB lists | TTTTGAG_MIR373 | 210 | 29 | 15632 | 1249 |
Peli1,Hdac1,Dhx58,Psip1,Atp2b4,Relb,Zfp281,Hif1a,Tmeff1,Wdfy1,St3gal5,Kctd12,Arid4a,Ccnj,Brd2,Flrt2,Casp8,Arf4,Jak2,Pkp4,Armc8,Pmepa1,Fignl2,Kpna3,Scyl2,Mob3b,Clec5a,Frmd4a,Arid5b |
| 2.661e-03 | -5.93 | MODULE_100 | MSigDB lists | MODULE_100 | 501 | 58 | 15632 | 1249 |
Pde4b,Ifit1bl2,Gja1,Cnp,Atp6v1d,Phlda1,Scn1b,Stoml1,Hmox1,Rtn1,Dusp5,Uchl1,Gng4,Rsbn1,Inpp1,Gng12,Tnf,Abcc5,Mtus1,Itpr1,D1Ertd622e,Tnc,Dusp8,Hspa2,Nupr1,Mthfr,Stat2,Rnd1,Myo10,Eno2,Ednrb,Lmo4,Rims3,Fabp7,St3gal5,Ppp4r2,Htra1,Kif5c,C3,Rac3,Cacnb3,Acsl1,Rgs1,Lhx2,Dnajb2,Cdkn1a,Ifit1bl1,Cx3cr1,Nr4a1,Fos,Psd,Vcan,Gadd45g,Dtnb,Stxbp1,Ccnd2,Rnd3,Angpt1 |
| 2.670e-03 | -5.93 | IL-3 Signaling Pathway | WikiPathways | WP373 | 99 | 21 | 4813 | 540 |
Jak2,Mapkapk2,Slc2a1,Crkl,Stat3,Nfkb1,Src,Mmp9,Bcl2l11,Socs3,Stat1,Ptk2,Pik3cd,Stat5a,Lyn,Hck,Cish,Tnfrsf1b,Tyk2,Syk,Map2k1 |
| 2.683e-03 | -5.92 | Deubiquitination | REACTOME pathways | R-MMU-5688426 | 236 | 34 | 8608 | 757 |
Psmd10,Traf2,Ddx58,Nlrp3,Psme2,Psma6,Psmb10,Ikbkg,Tnip1,Mdm2,Birc3,Ripk2,Psmb8,Kat2b,Psme1,Psmb6,Usp25,Ifih1,Hif1a,Usp42,Nod1,Psmb9,Usp18,Psme2b,Birc2,Adrb2,Nod2,Keap1,Uchl1,Tnfaip3,Usp12,Nfkbia,Tnip3,Actb |
| 2.684e-03 | -5.92 | GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_DN | MSigDB lists | GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_DN | 182 | 26 | 15632 | 1249 |
Jak2,Rab20,Nxf1,Ifit3b,Ifih1,Ddx58,Rtn1,Prdm1,Ebi3,Stat4,Kdm5b,Ppp4r2,H2-Aa,Srxn1,Cysltr2,Ociad1,Akt3,Oas3,Osm,Gbp7,Ifit3,Ppm1k,Cnp,Ctu1,4930523C07Rik,Dync1h1 |
| 2.684e-03 | -5.92 | GSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_UP | 182 | 26 | 15632 | 1249 |
Hcls1,Adam19,Epsti1,Vrk2,Casp7,Kpna3,Il13ra1,Serpinb9,Map2k4,Inpp5b,H2-Aa,Tifa,Sh3bp4,Cd86,Cd80,Slamf7,Enpp4,Hk3,Abr,Palld,Nlrp3,Pde1b,Cers6,Stat5a,Psmb9,B4galt4 |
| 2.684e-03 | -5.92 | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_UP | 182 | 26 | 15632 | 1249 |
Il15ra,5430427O19Rik,Dr1,Asf1a,Trib1,Acsl1,Rcsd1,Fam111a,Tnfsf4,Mtdh,Ptger4,Egr3,Ell2,Phlda1,Samsn1,Slc4a7,Dcun1d3,Cd83,Slc16a1,P2ry14,Aim2,Ube2e1,Il6,Swap70,Dnaja1,Cited2 |
| 2.684e-03 | -5.92 | GSE10325_CD4_TCELL_VS_BCELL_UP | MSigDB lists | GSE10325_CD4_TCELL_VS_BCELL_UP | 182 | 26 | 15632 | 1249 |
Rasgrp1,Stat4,Tnfsf14,Ccl5,Ap3m2,Tnfsf10,Tmem123,Pim1,Dyrk2,Atp10a,Sema4c,Cpd,Acvr1,Optn,Cish,Tnfsf8,Bnip3,Timp1,Tnfaip3,Samhd1,Atp2b4,Pde3b,Ccnd2,Upp1,Stxbp1,Plk3 |
| 2.684e-03 | -5.92 | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP | MSigDB lists | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP | 182 | 26 | 15632 | 1249 |
Apba1,Fndc3a,Ptk2,Endod1,Tmem176b,Irs2,Il4ra,Mob3b,Prnp,Cutc,Pde3b,Sdc4,Lrrc8c,Cd38,Ahrr,N4bp1,Gpsm2,Tcf4,Irf8,Cp,Pdpn,D1Ertd622e,Tmeff1,Fut8,Tmem176a,Rin2 |
| 2.684e-03 | -5.92 | YAGI_AML_FAB_MARKERS | MSigDB lists | YAGI_AML_FAB_MARKERS | 182 | 26 | 15632 | 1249 |
Aoah,Txnrd1,Casp1,Rras2,Pbx1,Cd164,Samhd1,Cd180,Nlrp3,Stat4,Tnfrsf1b,Cav1,Plod2,Med21,Orai2,Bambi,Tnfaip2,Hmgcs1,Max,Ell2,Cd200,Pim2,Mppe1,Arid5b,Il2rg,Nr4a3 |
| 2.684e-03 | -5.92 | GSE7460_TCONV_VS_TREG_LN_UP | MSigDB lists | GSE7460_TCONV_VS_TREG_LN_UP | 182 | 26 | 15632 | 1249 |
Ikzf1,Acvrl1,Cers6,Kremen1,Pik3r5,Gramd1a,Dse,Acpp,Pde3b,Myo10,Slc30a4,Cnn3,Ppp1r15b,Lmo4,Ppp2r1b,Ldlr,Dusp28,Snn,Pim2,Dyrk2,St3gal1,Max,Gpd2,Sema4a,Nr4a3,Tmem229b |
| 2.684e-03 | -5.92 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | 182 | 26 | 15632 | 1249 |
Sap30,Ddit4,Hk2,Rnf14,Psat1,Idi1,Clic4,Bcl2a1a,Cmpk2,Trafd1,Glrx,Fam162a,Dck,Cd200,Serpinb9,Mthfd2,Trib3,Rhoq,Bcl2a1d,Bcl2a1b,Eif2ak2,Slc2a1,Tpi1,Mcoln2,Jmjd6,Cyth3 |
| 2.684e-03 | -5.92 | GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_UP | MSigDB lists | GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_UP | 182 | 26 | 15632 | 1249 |
Sat1,Cnot4,Mafk,Errfi1,4932438A13Rik,Gsr,Gadd45g,Gramd1a,Ttc39c,Ripk3,Gbp2,Pgs1,Slc30a4,Hlx,Cdkn2d,Prnp,Zfp36,Spint2,Zc3h12c,Serpine1,Lhx2,Nfil3,Frmd6,Ripk2,Ak4,Map3k8 |
| 2.684e-03 | -5.92 | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_DN | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_DN | 182 | 26 | 15632 | 1249 |
Ap3b1,Triobp,Rab9,Acpp,Birc2,Rab32,Rras2,Crlf3,Upp1,Rnf135,Trim12c,Hlx,Nfkbiz,G3bp2,Flnb,Slpi,Tor1aip1,Casp8,Rgl1,Arid4a,Elmod2,Rbms1,Cpeb4,Tmod3,Zc3h12a,Parp3 |
| 2.684e-03 | -5.92 | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 182 | 26 | 15632 | 1249 |
Ifi208,Trim14,Sap30,Ifi211,Rap1gap2,Ifi203,Oas2,Snx2,Stoml1,Ttc9c,Ccr1,Mndal,Plcl2,Sp110,Ldha,Ifi204,Ifi213,Cd302,Ifi209,Ifi205,Ube2f,Ifi207,Hvcn1,Aim2,Ifi214,Usp18 |
| 2.684e-03 | -5.92 | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP | MSigDB lists | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP | 182 | 26 | 15632 | 1249 |
Ehd1,Syk,Swap70,Cdyl2,Chst11,Lztfl1,Ubash3b,Prnp,Ifih1,Traf1,Spred1,Tor3a,Gja1,Ccne1,Cd86,Tmem26,Hmgcs1,Endod1,Rcan1,Itga9,Dusp16,Tmem219,Agpat4,Dnajb2,Frmd6,Abcc4 |
| 2.687e-03 | -5.92 | multicellular organismal process | biological process | GO:0032501 | 7388 | 551 | 20694 | 1406 |
Casz1,Ddx4,Cyfip1,Mgat1,Ptgs2,Ier2,Syne2,Bcl9,Mmd,Dusp5,Plscr1,Spn,Rapgef2,Marf1,F10,Adora2b,Tpi1,Itpr1,Samd9l,Acod1,Tmeff1,F11r,Dbnl,Spire1,Pbx1,Osm,Klf7,Cav1,Mmp9,Sirt1,Plcl2,Cd164,Lgals9,Il15ra,Stxbp1,Cited2,Il1a,Tnf,Rsad2,Tcf4,Jun,Angpt1,Ikzf1,Asah2,Taf4b,Rasgrp1,Ccl12,Atf3,Psd,Nlgn2,Mycl,Icam1,Jmjd6,Irs2,Kat2b,Uchl1,Arid5b,Aida,Insl6,Rpgrip1l,Col27a1,Lipg,Gclc,Tnfaip2,Pou3f1,Ifna5,Mthfr,Serpinb6b,Tmod3,Gpd2,Stk40,Lrp4,Mul1,Hlx,Hsd17b7,Clec5a,Tut7,B3gnt5,Rrs1,Il18rap,Ldlr,Casp1,Jarid2,Micall2,Hap1,Marco,Foxp4,Usp53,Gpr18,Sbds,Il18,Zc3h12a,Sgcb,Scarf1,Chmp4b,Gfi1,Trip10,Prokr1,Kif3c,Usp42,Lnpk,Cenpe,Plpp3,Tspo,Irf1,Map2k4,Intu,Rab21,Asf1a,Il10,Cnp,Dach1,Cx3cr1,Sema4c,Edn1,Prkar2b,Rai14,Trip13,Dnaja1,Socs7,Fas,Papss2,Hmga1,Irf4,Itga4,Gclm,Ccr3,Casp7,Sav1,Mmp14,Acvr1b,Nfkb2,Phgdh,Lox,Ttc39c,Cnn2,Mcm9,Plek,Tnfsf9,Nrp2,Lhx2,Bmp2,Ifnar1,Keap1,Rcn1,Cdk5r1,Nfkb1,Acp5,Ifna1,Btg2,Isg15,Diaph2,Acp2,Il1b,Tet2,Sik3,Cacybp,P2ry2,Spaca6,Inpp5b,P2ry12,Agtrap,Acvrl1,Ifna6,Nck1,Sdc4,Vezt,Katna1,Pla2g4a,Gys1,Etv5,Trim56,Rbbp8,Pikfyve,Zfp513,Nampt,Casp8,Phf6,Cdkn1a,Tmem67,Stxbp3,Mosmo,Clic4,Srgn,Slc7a5,Ednrb,Ifitm1,Slc28a2,Agrn,Il12b,Arg2,Vcan,Flt1,Lif,Slc25a25,Psma6,Gpc1,Heatr9,Bcl2l11,Nr3c1,Map2k1,Dock10,Eif4g2,Snx10,Odc1,Fpr2,Errfi1,Timp1,Lrp11,Lcp2,Tlr6,Jak2,Tcea1,Rap1gap2,Sphk1,Rictor,Inhba,Irf7,Tnfaip3,Tnfrsf1b,Nlrp3,Akt3,Rgs14,Ifna2,Socs3,Arid4a,Tnc,Kif5c,Apobec3,Herc6,Golga3,Azi2,Plagl1,Pdpn,Stat5a,Batf,Ccl2,Adrb2,Slc30a1,Evl,Med21,Slamf8,Mllt6,Sipa1l1,Ifrd1,Antxr1,Spen,Hspa2,Gsr,Il15,Csf1,Nupr1,Igsf9,Col18a1,Pdgfrb,Cebpd,Fzd5,Ptpn2,Nr1h3,Tle3,Prag1,Prkx,Rac3,Kdm5b,Etv6,Ptk2,Nes,Atm,Abr,Fos,Bcl2a1d,Mturn,Cdyl,Cd38,Timeless,Adgrl2,Ptch1,Lmo4,Htr2b,Clcf1,Parp11,Ahr,Il4ra,Slc7a11,Kremen1,Chst11,Atp11a,Lyn,Ier3,Arf4,Fam20c,Hhex,Pik3r6,Axl,Irf8,Gpsm2,Txnrd1,Hp,Ccl4,Syk,Pde3b,Ifi204,Ccl3,Zswim4,Fzd1,Sod2,Col4a2,Noct,Prdm1,Eya4,Pml,Ccr1,Ciapin1,Nox1,Wars,Msr1,Tshz1,Fndc3a,Igf1r,Fgr,Ankrd17,Ccl5,Nod1,Cdkn2d,Ifnb1,Junb,Actb,Malt1,Pde4b,Sec24b,C3,Cd74,Htra1,Spred1,Scn1b,Nos2,Tab2,Ifna4,Csf3,Gcnt2,Icosl,Trmt1l,Map4k4,Tnfsf8,Ptprj,Tlk2,Gsta3,Tdrd7,Flnb,Tlr2,Clec4d,Hmox1,Clec4e,Tiparp,Cd300lf,Notch1,Rhoh,Mmp13,Ets2,Atp2b4,Ptger4,Mov10,Mcoln2,Abcb1a,Adora2a,Rnf114,Aim2,Ehd1,Plau,Adgrg6,Adam19,Ust,Hdac1,Tnfsf4,Nr4a1,Hinfp,Acvr1,Plaur,S100a8,Homer1,Tsku,Stap1,Tent2,D16Ertd472e,H2-Q7,Lrp8,Pla2g7,Nod2,Flrt2,Serpine1,Adap2,Zfp36,Gadd45g,Nectin2,Hivep3,Enpp4,Itgb8,Clic5,Morc3,Hif1a,Itga5,Ccnd2,Kdm4a,Il6,Jag1,Cflar,Sap30,Vasp,Trem1,Prnp,Cd34,Cacnb3,Prdm9,Thbs1,Plk2,Samhd1,Sema4a,Rel,Cemip2,Dnaaf3,Gja1,Itgav,Casp3,Rtp4,Nr4a3,Ccnd1,Relb,Zmynd15,Palld,Procr,Clmp,Pdgfc,Mdm2,Slc7a2,Ppp2r3a,Hmga2,Tal2,Fubp1,Mapkapk2,Gfpt1,Egr2,Kdr,Setdb2,Col11a2,Ubash3b,Cx3cl1,Kitl,Cacna1d,Serp1,Myd88,Met,Mafk,Ift57,H3f3b,Zfp281,Shisa3,Fcgr2b,Arid5a,Gch1,Eno1,Vcam1,Ext1,Cxcl14,Fut8,Rgcc,Rab10,Egr1,Zhx2,Calcrl,Notch2,Pdlim7,Slc4a7,Fabp7,Gdf15,Bcl6,Plod3,Gadd45b,Spred3,Rnd1,Kdm6b,Cgas,Il1rn,Mark2,Rcan1,Ptafr,Mafg,Pdgfb,Dst,Batf2,Lpar1,Stat3,Src,H2-Ab1,Egr3,Plekha5,Sema3c,4932438A13Rik,Hcls1,Ampd3,Lst1,Kcnj2,Nlrc4,Spint2,Stat1,Bcor,Prdx5,Flrt3,Crkl,Ripk3,Adar,Maff,Mthfd1l,Apba1,Swap70,Pou2f2,Optn,Znrf3,Vegfc,Tulp3,Phactr4,Mecp2,Hopx,Ap3b1,Spic,Apaf1,Tlr9,Pf4,Slc9a1,Ddit4,Sdc2,Ezr,Bbx,Birc2,Ntng2,Csrnp1,Triobp,Klf2,Pde1b,Dock4,Dennd1b,Spry2,Plagl2,Htr2a,Vps54,Pde5a,Myc,Olfr56,Zeb1,Dync1i2,Rnf19b,Ppp4r2 |
| 2.690e-03 | -5.92 | chordate embryonic development | biological process | GO:0043009 | 811 | 76 | 20694 | 1406 |
Phf6,Casp8,Il10,Rbbp8,Acvr1,Hinfp,Intu,Vezt,Sdc4,Med21,Prdm1,Ift57,Slc30a1,Apaf1,Acvrl1,Spic,Angpt1,Inpp5b,Fzd1,Hopx,Tulp3,Phactr4,Cited2,Socs3,Mmp14,Zeb1,Itga4,Plod3,Sec24b,Rpgrip1l,Ifitm1,Fzd5,Pdgfrb,Junb,Notch2,Klf2,Edn1,Ext1,Vcam1,Sema4c,Eno1,Bmp2,Map2k1,Lhx2,Sema3c,Hsd17b7,Bcl2l11,Vasp,Mgat1,Phgdh,Atm,Pdgfb,Lif,Mthfr,Mafg,Acvr1b,Hif1a,Hhex,Notch1,Apba1,Mthfd1l,Sbds,Atp11a,Chst11,Pbx1,Maff,Adar,Rcn1,Keap1,Casp3,Bcor,Lmo4,Gja1,Ptch1,Itgav,Spint2 |
| 2.693e-03 | -5.92 | phospholipid metabolic process | biological process | GO:0006644 | 291 | 33 | 20694 | 1406 |
Sgms2,Pla2g7,Plpp1,Hmgcs1,Cish,Socs7,Dgkh,Lpcat2,Acsl5,Mppe1,Pdgfrb,Socs1,Inpp5b,Socs3,Pgap2,Inpp1,Agpat4,Plaat3,Atm,Mecp2,Plpp3,Idi1,Dgka,Pla2g4a,Pikfyve,Plek,Pgs1,Pigv,Plscr1,Cept1,Smpdl3b,Pik3cd,Etnk1 |
| 2.696e-03 | -5.92 | positive chemotaxis | biological process | GO:0050918 | 53 | 10 | 20694 | 1406 |
Cxcl10,Angpt1,Met,Vegfc,Pdgfb,Ccl5,Cx3cl1,Ptprj,Saa3,Fpr2 |
| 2.696e-03 | -5.92 | negative regulation of smooth muscle cell proliferation | biological process | GO:0048662 | 53 | 10 | 20694 | 1406 |
Il15,Hmox1,Ptgir,Il12b,Il10,Sod2,Cav1,Tnfaip3,Cdkn1a,Trib1 |
| 2.701e-03 | -5.91 | Apoptotic machinery | KEGG pathways | mmu_M00685 | 4 | 3 | 7931 | 713 |
Apaf1,Casp7,Casp3 |
| 2.701e-03 | -5.91 | Apoptotic machinery | KEGG pathways | M00685 | 4 | 3 | 7931 | 713 |
Apaf1,Casp3,Casp7 |
| 2.711e-03 | -5.91 | GO_RESPONSE_TO_RADIATION | MSigDB lists | GO_RESPONSE_TO_RADIATION | 388 | 47 | 15632 | 1249 |
Icam1,Hif1a,F11r,Plk3,Pml,Rgs14,Ifi205,Ifi209,Dusp1,Ifi213,N4bp1,Mecp2,Ccnd1,Tlk2,Mdm2,Casp3,Pde1b,Ptgs2,Cxcl10,Il12b,Il1b,Vcam1,Asns,Ppp1r15a,Txn1,Junb,Ifi208,Trim13,Ifi214,Egr1,Cdkn2d,Ifi207,Fos,Jun,Ccl12,Myc,Ifi204,Hmgcs1,Socs3,Cdkn1a,Cav1,Mndal,Atm,Dcun1d3,Sirt1,Ifi203,Ifi211 |
| 2.714e-03 | -5.91 | JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP | MSigDB lists | JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP | 53 | 11 | 15632 | 1249 |
Ppp1r14b,Hmox1,Tmem176b,Marcksl1,Klf6,Ccnd2,Fos,Stat3,Ppfibp1,Ccnd1,Chst11 |
| 2.714e-03 | -5.91 | LIM_MAMMARY_LUMINAL_PROGENITOR_UP | MSigDB lists | LIM_MAMMARY_LUMINAL_PROGENITOR_UP | 53 | 11 | 15632 | 1249 |
Cd14,Il4i1,Ccdc88b,Tnfaip2,Ctsc,Il15,Hivep3,C3,S100a8,Hsd17b12,Acsl1 |
| 2.722e-03 | -5.91 | GTGCCAA_MIR96 | MSigDB lists | GTGCCAA_MIR96 | 278 | 36 | 15632 | 1249 |
Ezr,Klf3,Sdc2,Mecp2,Hspa2,Prkce,Plagl1,St3gal3,Rnf139,Csrnp1,Cd164,Tsku,Slc25a25,Cav1,Plod2,Map2k1,Slc7a8,Rictor,Rap1gap2,Casp2,Cnn3,Spen,Ext1,Csf1,Pdlim7,Trib3,St7,Arid5b,Nr4a3,Cpeb4,Crkl,Pcgf5,Stard7,Pmepa1,Zhx2,Nlgn2 |
| 2.726e-03 | -5.91 | GO_MODULATION_BY_SYMBIONT_OF_HOST_CELLULAR_PROCESS | MSigDB lists | GO_MODULATION_BY_SYMBIONT_OF_HOST_CELLULAR_PROCESS | 25 | 7 | 15632 | 1249 |
Tnip1,Serpinb9,Casp8,Kpna3,Itgav,Bcl2l11,Zc3h12a |
| 2.726e-03 | -5.91 | GNF2_SNRK | MSigDB lists | GNF2_SNRK | 25 | 7 | 15632 | 1249 |
Rasgrp1,Parp8,Ccl5,Lcp2,Itgal,Arhgef3,Casp8 |
| 2.726e-03 | -5.91 | PID_GLYPICAN_1PATHWAY | MSigDB lists | PID_GLYPICAN_1PATHWAY | 25 | 7 | 15632 | 1249 |
Src,Flt1,Gpc1,Prnp,Lyn,Fgr,Hck |
| 2.726e-03 | -5.91 | GO_REGULATION_OF_MACROPHAGE_ACTIVATION | MSigDB lists | GO_REGULATION_OF_MACROPHAGE_ACTIVATION | 25 | 7 | 15632 | 1249 |
Stap1,Thbs1,Cd74,Slc7a2,Nr1h3,Il4ra,Zc3h12a |
| 2.726e-03 | -5.91 | MODULE_488 | MSigDB lists | MODULE_488 | 25 | 7 | 15632 | 1249 |
Kat2b,Il1a,Eif2ak2,Il1b,Cdkn1a,Btg2,Il6 |
| 2.726e-03 | -5.91 | REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 | MSigDB lists | REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 | 25 | 7 | 15632 | 1249 |
Src,Gng4,Gna15,Pla2g4a,Gnb4,Gng11,Gng12 |
| 2.726e-03 | -5.91 | PID_P38_MKK3_6PATHWAY | MSigDB lists | PID_P38_MKK3_6PATHWAY | 25 | 7 | 15632 | 1249 |
Gadd45g,Tab2,Traf2,Atm,Txn1,Gadd45b,Map3k6 |
| 2.726e-03 | -5.91 | GO_NEGATIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | 25 | 7 | 15632 | 1249 |
Hmox1,Tnf,Bcl6,Il10,Irak3,Angpt1,Ifnb1 |
| 2.726e-03 | -5.91 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA | MSigDB lists | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA | 25 | 7 | 15632 | 1249 |
Gng11,Gnb4,Akt3,Gng12,Pik3r5,Gng4,Pik3r6 |
| 2.729e-03 | -5.90 | positive regulation of peptidyl-threonine phosphorylation | biological process | GO:0010800 | 29 | 7 | 20694 | 1406 |
Sphk1,Tnks1bp1,S1pr2,Phip,Met,Ripk2,Irgm2 |
| 2.729e-03 | -5.90 | negative regulation of protein processing | biological process | GO:0010955 | 29 | 7 | 20694 | 1406 |
Ctla2a,Birc2,Thbs1,Mdm2,Birc3,Serpine1,Cst7 |
| 2.729e-03 | -5.90 | ERK1 and ERK2 cascade | biological process | GO:0070371 | 29 | 7 | 20694 | 1406 |
Map2k1,Ccr3,Itgav,Htr2b,Kdr,Myc,Ptger4 |
| 2.729e-03 | -5.90 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | GO:1902042 | 29 | 7 | 20694 | 1406 |
Icam1,Hmox1,Rnf34,Cflar,Serpine1,Rffl,Tnfaip3 |
| 2.729e-03 | -5.90 | positive regulation of mast cell activation | biological process | GO:0033005 | 29 | 7 | 20694 | 1406 |
Fgr,Syk,Stxbp1,Adora2b,Il4ra,Nr4a3,Nectin2 |
| 2.729e-03 | -5.90 | positive regulation of peptidyl-serine phosphorylation of STAT protein | biological process | GO:0033141 | 29 | 7 | 20694 | 1406 |
Ifna5,Ifna2,Ifna1,Lif,Ifna6,Ifna4,Ifnb1 |
| 2.729e-03 | -5.90 | negative regulation of protein maturation | biological process | GO:1903318 | 29 | 7 | 20694 | 1406 |
Thbs1,Mdm2,Ctla2a,Birc2,Serpine1,Birc3,Cst7 |
| 2.734e-03 | -5.90 | transition metal ion transmembrane transporter activity | molecular function | GO:0046915 | 36 | 8 | 20217 | 1400 |
Slc31a1,Slc31a2,Slc39a4,Slc30a4,Slc25a37,Slc30a1,Slc39a13,Slc39a14 |
| 2.737e-03 | -5.90 | regulation of phosphoprotein phosphatase activity | biological process | GO:0043666 | 99 | 15 | 20694 | 1406 |
Jak2,Vcan,Ppp2r1b,Phactr4,Tnf,Ppp6r1,Ppp2r5a,Ppp1r15a,Pdgfrb,Ppp1r14b,Ppp1r15b,Ppp2r2a,Ppp2r3a,Ppp4r2,Rcan1 |
| 2.742e-03 | -5.90 | GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_UP | MSigDB lists | GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_UP | 173 | 25 | 15632 | 1249 |
Upp1,Nxf1,Pml,Cd34,Il15,Clec4e,Cited2,Mecp2,Rin2,Sdc2,Sat1,Gclm,Cish,Dusp2,Ifi44,Grina,Rab20,Itga5,Tnfaip2,Tap2,Snx10,Rap1gap2,Vasp,Spen,H2-Aa |
| 2.742e-03 | -5.90 | GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN | MSigDB lists | GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN | 173 | 25 | 15632 | 1249 |
Hivep2,Ifit2,Rhbdf2,Nlrc4,Prkce,Pcx,Pgs1,Atf3,Fgr,Papss2,Nr1h3,Atp11b,S100a8,Ifit3,Itgal,Oas1a,Bst1,C3,Oas1g,Rab20,Ifit3b,Acsl1,Ttc39b,Cd300lf,Cd82 |
| 2.742e-03 | -5.90 | GSE29618_MONOCYTE_VS_PDC_DN | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DN | 173 | 25 | 15632 | 1249 |
Dnase1l3,Rhoh,Mapkapk2,Lrp8,Fchsd2,Irf4,Mdn1,Ppp1r14b,Slc7a11,Slc2a1,Tcf4,Adam19,Zhx2,Dusp5,Dck,Mcm6,Il2rg,Odc1,Slc7a5,Phlpp2,Flnb,Egln3,Rims3,Irf7,Irf8 |
| 2.742e-03 | -5.90 | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 173 | 25 | 15632 | 1249 |
Hhex,Slc30a1,Crlf3,Pde3b,Hvcn1,Abcc5,Rnf114,Acpp,Casp3,Ly75,Rab11fip1,Sdc2,Ogfrl1,Hdac1,Psmb6,Mppe1,Orai2,Adam19,Socs7,Hsd17b12,4930523C07Rik,Casp8,Tlr1,Kctd12,Tbc1d13 |
| 2.742e-03 | -5.90 | GSE18893_TCONV_VS_TREG_2H_CULTURE_UP | MSigDB lists | GSE18893_TCONV_VS_TREG_2H_CULTURE_UP | 173 | 25 | 15632 | 1249 |
Arid5a,Cers6,Gadd45g,Aebp2,Mllt6,Bbx,Rhoq,Nxf1,Pgm1,Hvcn1,Il15,Sgk3,Lnpep,Inpp5b,Map3k8,Phf6,Tgfbi,Dtx2,Usp31,Dram1,Rnf19b,Ebi3,Fmnl2,Mob3c,Cd300lf |
| 2.742e-03 | -5.90 | GSE3982_MAST_CELL_VS_NKCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_NKCELL_UP | 173 | 25 | 15632 | 1249 |
Tax1bp1,Clic4,Esd,Pkp4,Pmepa1,Pgk1,Snn,Abcc4,Larp1,Ptk2,Dram1,Adora2b,Rab20,Ampd3,Rtn2,Alas1,Lmo4,Etv5,Stxbp1,Pla2g4a,Rai14,Acvr1,Hspa2,Cers6,Dpy19l1 |
| 2.743e-03 | -5.90 | Platinum drug resistance | KEGG pathways | mmu01524 | 76 | 15 | 7931 | 713 |
Pik3cd,Casp8,Slc31a1,Cdkn1a,Fas,Birc2,Apaf1,Atm,Pmaip1,Birc3,Akt3,Mdm2,Cycs,Casp3,Gsta3 |
| 2.743e-03 | -5.90 | Platinum drug resistance | KEGG pathways | ko01524 | 76 | 15 | 7931 | 713 |
Birc2,Fas,Pik3cd,Casp8,Cdkn1a,Slc31a1,Mdm2,Akt3,Cycs,Gsta3,Casp3,Atm,Apaf1,Birc3,Pmaip1 |
| 2.749e-03 | -5.90 | neuron part | cellular component | GO:0097458 | 1936 | 162 | 20747 | 1409 |
Htr2a,Casp3,Nqo1,Cnn3,Sqstm1,Fos,Grk3,Stx11,Slc30a1,Chmp4b,Clic5,Cd200,Dmxl2,Magohb,Cdk5r1,Psd,Rhoc,Glrx,Casp8,Actb,Flrt3,Cx3cr1,Stxbp1,Cpeb4,Ldlr,Kcna3,Slc31a1,Bnip3,Uchl1,Rpgrip1l,Sirt1,Sdc2,Mark2,Src,Ass1,Pde4b,Arf4,Orai2,Fcho2,Vezt,Xrn1,Prnp,Hdc,Plekha5,Slc16a3,Prkar2b,Plk2,Adora2a,Dync1h1,Pkp4,Palld,Rab10,Kctd12,Tnfrsf1b,Prkce,Stat3,Txnrd1,Rims3,Agrn,Eno2,Cx3cl1,Rab21,Fzd1,Marcksl1,Casp4,Dock4,Eno1,Igf1r,P2ry2,Atp2b4,Ntng2,Abr,Katna1,Mul1,Igsf8,Kif3c,Pdgfb,Tnf,Ccr1,Casp1,Map2k1,Myo10,Nr3c1,Triobp,Fcgr2b,Lrp8,Ccl2,Igsf9,Sipa1l1,Tpx2,Map2k4,Stau1,Ctla2a,Lpar1,Adrb2,Cd40,Sema4c,Kremen1,Kif5c,Homer1,Fscn1,Hdac1,Lrp4,Rapgef2,Apba1,Optn,Stx6,Gpc1,Rgs14,Adgrl2,Stat1,Flrt2,Phlpp1,Cyfip1,Ptch1,Eif4g2,Daxx,Itga4,Lyn,Htr2b,Ppfia3,Dst,Ptk2,Ppfibp2,Plk3,Rab3ip,Flnb,Scn1b,Nfkb1,Sphk1,Nrp2,Dbnl,Rac3,Ift57,Hap1,Cacna1d,Plat,Kdr,Fchsd2,Max,Met,Myd88,Dock10,Fas,Slc4a7,Pde1b,Nlgn2,Rap1gap2,Itpr1,Acp2,Kcnj2,Ero1l,Stxbp3,Txn1,Phlpp2,Micall2,Ptger4,Ptgs2,Myc,Fabp7,Acvrl1,Cacybp |
| 2.749e-03 | -5.90 | GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | MSigDB lists | GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | 288 | 37 | 15632 | 1249 |
Cyfip1,Swap70,Ezr,Cnn2,Triobp,Kcnj2,Edn1,Rhoq,Prkce,Stap1,F11r,Icam1,Cdk5r1,Nck1,Evl,Asap3,Hck,Sdc4,Cdc42ep2,Cav1,Pdgfrb,Pde4b,Plek,Myadm,Csf3,Rictor,Vasp,Slc9a1,Lpar1,Cdc42ep4,Spire1,Ptger4,Tmod3,Frmd6,Fscn1,Whamm,Hcls1 |
| 2.764e-03 | -5.89 | KAYO_AGING_MUSCLE_DN | MSigDB lists | KAYO_AGING_MUSCLE_DN | 119 | 19 | 15632 | 1249 |
Ifi207,Polr2g,Ifi214,Ifi204,Ell2,Rars,Psma6,Ifi203,Top3a,Ifi208,Ifi211,Mndal,Ifi209,Casp4,Ifi205,Nfkb1,Sod2,Lnpep,Ifi213 |
| 2.768e-03 | -5.89 | GO_PROTEIN_UBIQUITINATION | MSigDB lists | GO_PROTEIN_UBIQUITINATION | 586 | 66 | 15632 | 1249 |
Rnf19a,Ube2e2,Trim56,Sirt1,Trim21,Psme2,Ubr4,Rabgef1,Psmb8,Birc3,Ankib1,Rnf31,Lnpep,Rnf14,Socs7,Znrf1,Rnf145,Asb13,Dtx2,Socs3,Cnot4,Peli1,Nlrc4,Psmd10,Crbn,Trim36,Spsb1,Rnf114,Vcpip1,Herc3,Fbxo4,Pttg1,Trim13,Znrf3,Mul1,Bcor,Uba7,Ube2l6,Med21,Keap1,Rnf19b,Herc6,Psmb6,Mdm2,Psma6,Cish,Rnf24,Rffl,Traf2,Klhl25,Psmb9,Birc2,Tnfaip3,Rnf34,Bfar,Traf5,Ube2f,Trim12c,Socs1,Dtx3l,Rnf135,Psmb10,Malt1,Ube2e1,Psme1,Rnf139 |
| 2.782e-03 | -5.88 | MODULE_137 | MSigDB lists | MODULE_137 | 502 | 58 | 15632 | 1249 |
Itpr1,Mtus1,Abcc5,Tnf,Hspa2,Dusp8,D1Ertd622e,Tnc,Rnd1,Stat2,Mthfr,Nupr1,Myo10,Atp6v1d,Cnp,Gja1,Pde4b,Ifit1bl2,Stoml1,Scn1b,Phlda1,Dusp5,Rtn1,Uchl1,Gng4,Hmox1,Gng12,Inpp1,Rsbn1,Fos,Nr4a1,Ifit1bl1,Cx3cr1,Dtnb,Gadd45g,Vcan,Psd,Ccnd2,Stxbp1,Angpt1,Rnd3,Rims3,Lmo4,Ednrb,Eno2,Htra1,Ppp4r2,St3gal5,Fabp7,Acsl1,Cacnb3,C3,Rac3,Kif5c,Cdkn1a,Dnajb2,Lhx2,Rgs1 |
| 2.796e-03 | -5.88 | regulation of G protein-coupled receptor signaling pathway | biological process | GO:0008277 | 129 | 18 | 20694 | 1406 |
Ccl5,Atp2b4,Tulp3,Htr2b,Edn1,C3,Rgs1,Fpr2,Rgs14,Acpp,Kctd12,Grk3,Adrb2,Rpgrip1l,Pde4b,Pde5a,Plek,Met |
| 2.804e-03 | -5.88 | mouse chr11 | chromosome location | mouse chr11 | 550 | 50 | 24173 | 1464 |
Adam19,Rel,Cdk5r1,Ccl7,Jmjd6,Il12b,Stat3,Heatr9,Adap2,Plek,Dbnl,Csf3,Mgat1,Ikzf1,Irf1,Stat5a,Ccl2,Ccl5,Sco1,Gm12185,Tgtp2,P4ha2,Wfdc17,Rnf135,Lif,Vps54,Ccl3,Mafg,Map2k4,Kcnj2,Igtp,Slfn1,Osm,Ccl9,Ccl12,Cpd,Slfn2,Dhx58,Ccl4,Peli1,Mllt6,Abr,Hap1,Nos2,Dusp14,Ksr1,Cnp,Psmb6,Ccl8,Crlf3 |
| 2.813e-03 | -5.87 | BIOCARTA_DC_PATHWAY | MSigDB lists | BIOCARTA_DC_PATHWAY | 19 | 6 | 15632 | 1249 |
Tlr9,Il10,Cd40,Ifnb1,Il12b,Tlr2 |
| 2.813e-03 | -5.87 | GO_RESPONSE_TO_LEPTIN | MSigDB lists | GO_RESPONSE_TO_LEPTIN | 19 | 6 | 15632 | 1249 |
Stat3,Edn1,Sirt1,Ccnd1,Nr4a3,Pid1 |
| 2.813e-03 | -5.87 | GO_ZINC_ION_HOMEOSTASIS | MSigDB lists | GO_ZINC_ION_HOMEOSTASIS | 19 | 6 | 15632 | 1249 |
Slc39a4,S100a8,Slc30a4,Slc30a1,Slc39a14,Slc39a13 |
| 2.813e-03 | -5.87 | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN | MSigDB lists | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN | 19 | 6 | 15632 | 1249 |
Plk2,Olfml3,Dusp4,Tcf4,Ccl12,Phlda1 |
| 2.813e-03 | -5.87 | GO_COPPER_ION_TRANSPORT | MSigDB lists | GO_COPPER_ION_TRANSPORT | 19 | 6 | 15632 | 1249 |
Slc31a2,Slc31a1,Cutc,Cp,Sco1,Cox17 |
| 2.813e-03 | -5.87 | GO_RESPONSE_TO_MUSCLE_STRETCH | MSigDB lists | GO_RESPONSE_TO_MUSCLE_STRETCH | 19 | 6 | 15632 | 1249 |
Nfkbia,Edn1,Slc9a1,Nfkb1,Fos,Jun |
| 2.813e-03 | -5.87 | AMIT_EGF_RESPONSE_240_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_240_MCF10A | 19 | 6 | 15632 | 1249 |
Bmp2,Pcdh7,Plau,Dusp4,Slc7a11,Ptafr |
| 2.813e-03 | -5.87 | GO_CELLULAR_RESPONSE_TO_FLUID_SHEAR_STRESS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_FLUID_SHEAR_STRESS | 19 | 6 | 15632 | 1249 |
Ptgs2,Klf2,Ass1,Src,Mmp13,Plau |
| 2.813e-03 | -5.87 | GO_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT | MSigDB lists | GO_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT | 19 | 6 | 15632 | 1249 |
Pdgfb,Cd34,Egr1,Notch1,Pdgfrb,Angpt1 |
| 2.813e-03 | -5.87 | GO_LAMELLIPODIUM_MEMBRANE | MSigDB lists | GO_LAMELLIPODIUM_MEMBRANE | 19 | 6 | 15632 | 1249 |
Itgav,Syne2,Vasp,Pdpn,Piezo1,Antxr1 |
| 2.813e-03 | -5.87 | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_SECRETION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_SECRETION | 19 | 6 | 15632 | 1249 |
Nod2,Nlrp3,Ifnar1,Casp1,Gsdmd,Aim2 |
| 2.816e-03 | -5.87 | MODULE_301 | MSigDB lists | MODULE_301 | 128 | 20 | 15632 | 1249 |
Oas1a,Mecp2,Rsad2,Spint2,Plac8,Abcc5,Irf8,Flrt2,Heatr6,Cmklr1,Tnfaip2,Hvcn1,Tap1,5430427O19Rik,Oas1g,Cd200,Kcna3,Il4ra,Rcsd1,Fgr |
| 2.816e-03 | -5.87 | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | MSigDB lists | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | 128 | 20 | 15632 | 1249 |
Mapkapk2,Trib3,Irs2,Ralgds,Ppp2r1b,Cdkn1a,Prkar2b,Nr4a1,Src,Dusp6,Map2k1,Stat3,Akt3,Prkce,Pde1b,Rictor,Phlpp1,Mdm2,Adora2a,Dusp4 |
| 2.817e-03 | -5.87 | spermatoproteasome complex | cellular component | GO:1990111 | 5 | 3 | 20747 | 1409 |
Psmb9,Psmb8,Psmb10 |
| 2.817e-03 | -5.87 | NLRP3 inflammasome complex | cellular component | GO:0072559 | 5 | 3 | 20747 | 1409 |
Gsdmd,Casp1,Nlrp3 |
| 2.817e-03 | -5.87 | GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 259 | 34 | 15632 | 1249 |
Gclc,Tnfaip3,Plk3,Psme1,Ube2e1,Pml,Rnf139,Psmb10,Ctsc,Tlk2,Mdm2,Psma6,Ezr,Dusp1,N4bp1,Rnf114,Psmd10,Psmb9,Dnajb2,Keap1,Ptk2,Rnf19b,Psmb6,Smc5,Trib3,Trib1,Psme2,Rnf19a,Ankib1,Psmb8,Atm,Rnf14,Plk2,Cav1 |
| 2.819e-03 | -5.87 | IL-5 Signaling Pathway | WikiPathways | WP151 | 68 | 16 | 4813 | 540 |
Lyn,Hck,Stat1,Jun,Nfkbia,Stat5a,Hcls1,Icam1,Syk,Nfkb1,Crkl,Stat3,Jak2,Pla2g4a,Socs1,Pim1 |
| 2.820e-03 | -5.87 | HALLMARK_MITOTIC_SPINDLE | MSigDB lists | HALLMARK_MITOTIC_SPINDLE | 192 | 27 | 15632 | 1249 |
Kif3c,Cdc42ep4,Pcgf5,Notch2,Fscn1,Cenpj,Tuba4a,Rictor,Ppp4r2,Flnb,Tpx2,Sass6,Palld,Abr,Nck1,Stau1,Cdc42ep2,Dock4,Rhof,Arhgef3,Bcl2l11,Rapgef5,Cenpe,Ezr,Dync1h1,Mid1,Katna1 |
| 2.820e-03 | -5.87 | plasma membrane lactate transport | biological process | GO:0035879 | 5 | 3 | 20694 | 1406 |
Slc16a1,Myc,Slc16a3 |
| 2.820e-03 | -5.87 | response to molecule of fungal origin | biological process | GO:0002238 | 5 | 3 | 20694 | 1406 |
Syk,Tlr2,Myd88 |
| 2.820e-03 | -5.87 | cytoplasmic sequestering of NF-kappaB | biological process | GO:0007253 | 5 | 3 | 20694 | 1406 |
Nfkbia,Nfkbib,Psmd10 |
| 2.820e-03 | -5.87 | positive regulation of hyaluronan biosynthetic process | biological process | GO:1900127 | 5 | 3 | 20694 | 1406 |
Ptger4,Pdgfb,Nfkb1 |
| 2.820e-03 | -5.87 | interleukin-18-mediated signaling pathway | biological process | GO:0035655 | 5 | 3 | 20694 | 1406 |
Il18rap,Il18,Pdgfb |
| 2.820e-03 | -5.87 | fever generation | biological process | GO:0001660 | 5 | 3 | 20694 | 1406 |
Il1b,Il1rn,Il1a |
| 2.820e-03 | -5.87 | negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | biological process | GO:1990441 | 5 | 3 | 20694 | 1406 |
Ppp1r15a,Jun,Nck1 |
| 2.820e-03 | -5.87 | T-helper 1 cell cytokine production | biological process | GO:0035744 | 5 | 3 | 20694 | 1406 |
Il12b,Il18,Il18rap |
| 2.820e-03 | -5.87 | positive regulation of I-kappaB phosphorylation | biological process | GO:1903721 | 5 | 3 | 20694 | 1406 |
Cx3cl1,Traf2,Cx3cr1 |
| 2.820e-03 | -5.87 | regulation of memory T cell differentiation | biological process | GO:0043380 | 5 | 3 | 20694 | 1406 |
Tnfsf4,Fgl2,Bcl6 |
| 2.820e-03 | -5.87 | type I interferon biosynthetic process | biological process | GO:0045351 | 5 | 3 | 20694 | 1406 |
Myd88,Ifnar1,Irf7 |
| 2.820e-03 | -5.87 | ciliary body morphogenesis | biological process | GO:0061073 | 5 | 3 | 20694 | 1406 |
Jag1,Tsku,Notch2 |
| 2.820e-03 | -5.87 | regulation of microglial cell migration | biological process | GO:1904139 | 5 | 3 | 20694 | 1406 |
Csf1,Stap1,P2ry12 |
| 2.820e-03 | -5.87 | positive regulation of skeletal muscle cell proliferation | biological process | GO:0014858 | 5 | 3 | 20694 | 1406 |
Jak2,Stat3,Sirt1 |
| 2.820e-03 | -5.87 | positive regulation of chronic inflammatory response | biological process | GO:0002678 | 5 | 3 | 20694 | 1406 |
Tnf,Adora2b,Pde5a |
| 2.820e-03 | -5.87 | B-1 B cell homeostasis | biological process | GO:0001922 | 5 | 3 | 20694 | 1406 |
Tnfaip3,Ahr,Hif1a |
| 2.820e-03 | -5.87 | regulation of interferon-alpha biosynthetic process | biological process | GO:0045354 | 5 | 3 | 20694 | 1406 |
Tlr9,Tlr3,Nmi |
| 2.820e-03 | -5.87 | positive regulation of cAMP-dependent protein kinase activity | biological process | GO:2000481 | 5 | 3 | 20694 | 1406 |
Sirt1,Rapgef2,Atp2b4 |
| 2.820e-03 | -5.87 | growth hormone receptor signaling pathway via JAK-STAT | biological process | GO:0060397 | 5 | 3 | 20694 | 1406 |
Jak2,Stat3,Stat5a |
| 2.820e-03 | -5.87 | connective tissue replacement | biological process | GO:0097709 | 5 | 3 | 20694 | 1406 |
Timp1,Il1a,Hif1a |
| 2.820e-03 | -5.87 | Fc receptor mediated stimulatory signaling pathway | biological process | GO:0002431 | 5 | 3 | 20694 | 1406 |
Nr4a3,Fcgr2b,Lyn |
| 2.820e-03 | -5.87 | negative regulation of cytokine secretion involved in immune response | biological process | GO:0002740 | 5 | 3 | 20694 | 1406 |
Il10,Angpt1,Tnf |
| 2.820e-03 | -5.87 | regulation of ovulation | biological process | GO:0060278 | 5 | 3 | 20694 | 1406 |
Inhba,Plat,Plau |
| 2.820e-03 | -5.87 | response to cisplatin | biological process | GO:0072718 | 5 | 3 | 20694 | 1406 |
Hmox1,Timeless,Slc31a1 |
| 2.820e-03 | -5.87 | negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation | biological process | GO:1903912 | 5 | 3 | 20694 | 1406 |
Ppp1r15a,Ppp1r15b,Nck1 |
| 2.820e-03 | -5.87 | regulation of mast cell proliferation | biological process | GO:0070666 | 5 | 3 | 20694 | 1406 |
Stat5a,Kitl,Lyn |
| 2.820e-03 | -5.87 | cellular response to hyperoxia | biological process | GO:0071455 | 5 | 3 | 20694 | 1406 |
Cav1,Nox1,Fas |
| 2.820e-03 | -5.87 | connective tissue replacement involved in inflammatory response wound healing | biological process | GO:0002248 | 5 | 3 | 20694 | 1406 |
Timp1,Hif1a,Il1a |
| 2.820e-03 | -5.87 | maintenance of protein location in mitochondrion | biological process | GO:0072656 | 5 | 3 | 20694 | 1406 |
Hk1,Tspo,Hk2 |
| 2.820e-03 | -5.87 | positive regulation of phosphatidylinositol biosynthetic process | biological process | GO:0010513 | 5 | 3 | 20694 | 1406 |
Htr2b,Fpr2,Htr2a |
| 2.820e-03 | -5.87 | positive regulation of extracellular matrix organization | biological process | GO:1903055 | 22 | 6 | 20694 | 1406 |
Il6,Fscn1,Rgcc,Pdpn,Cflar,Phldb1 |
| 2.820e-03 | -5.87 | T cell mediated cytotoxicity | biological process | GO:0001913 | 22 | 6 | 20694 | 1406 |
Stx11,Serpinb9,Serpinb9b,Ctsc,Raet1e,H60b |
| 2.820e-03 | -5.87 | natural killer cell mediated immunity | biological process | GO:0002228 | 22 | 6 | 20694 | 1406 |
Stx11,Il18,Prdx1,Raet1e,H60b,Rnf19b |
| 2.820e-03 | -5.87 | positive regulation of alpha-beta T cell proliferation | biological process | GO:0046641 | 22 | 6 | 20694 | 1406 |
Il18,Syk,Cd80,Tnfsf4,Il12b,Ripk2 |
| 2.820e-03 | -5.87 | positive regulation of myoblast fusion | biological process | GO:1901741 | 22 | 6 | 20694 | 1406 |
Cxcl9,Gdf15,Ccl8,Tnfsf14,Il4ra,Ehd1 |
| 2.820e-03 | -5.87 | positive regulation of lipid storage | biological process | GO:0010884 | 22 | 6 | 20694 | 1406 |
Msr1,Zc3h12a,Ikbke,Hilpda,Ehd1,C3 |
| 2.820e-03 | -5.87 | positive regulation of endothelial cell apoptotic process | biological process | GO:2000353 | 22 | 6 | 20694 | 1406 |
Thbs1,Itga4,Col18a1,Cd40,Ccl12,Rgcc |
| 2.820e-03 | -5.87 | regulation of protein polyubiquitination | biological process | GO:1902914 | 22 | 6 | 20694 | 1406 |
Fbxo4,Parp10,Birc2,Nmi,Nod2,Birc3 |
| 2.824e-03 | -5.87 | mouse chr2|2 C1.1 | chromosome location | mouse chr2|2 C1.1 | 41 | 8 | 24173 | 1464 |
Cd302,Acvr1,Ly75,Fmnl2,Nmi,Rbm43,Pkp4,Rnd3 |
| 2.840e-03 | -5.86 | GSE35543_IN_VIVO_NTREG_VS_IN_VITRO_ITREG_DN | MSigDB lists | GSE35543_IN_VIVO_NTREG_VS_IN_VITRO_ITREG_DN | 137 | 21 | 15632 | 1249 |
Ube2e2,Mlkl,Ikzf1,Bcorl1,Dusp8,Itpr1,Arhgef3,Plekha2,Tank,Pde4b,Card6,Sesn3,Pfkfb3,Tmem123,Slamf8,Ddx58,Kcna3,Pim1,Ifih1,Fas,Rhoh |
| 2.851e-03 | -5.86 | BASSO_CD40_SIGNALING_DN | MSigDB lists | BASSO_CD40_SIGNALING_DN | 61 | 12 | 15632 | 1249 |
Btg2,Isg20,Orai2,Tspo,Rapgef2,Cd38,Prkar2b,Rapgef5,Syk,Bcl6,St3gal6,Rims3 |
| 2.851e-03 | -5.86 | KEGG_COLORECTAL_CANCER | MSigDB lists | KEGG_COLORECTAL_CANCER | 61 | 12 | 15632 | 1249 |
Pik3cd,Rac3,Ralgds,Fos,Map2k1,Jun,Pik3r5,Ccnd1,Cycs,Casp3,Akt3,Myc |
| 2.851e-03 | -5.86 | REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | MSigDB lists | REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | 61 | 12 | 15632 | 1249 |
Cdkn1a,Psmb6,Psme1,Max,Psmb10,Myc,Psme2,Psma6,Ccne1,Psmb8,Psmd10,Psmb9 |
| 2.851e-03 | -5.86 | PID_MYC_REPRESS_PATHWAY | MSigDB lists | PID_MYC_REPRESS_PATHWAY | 61 | 12 | 15632 | 1249 |
Rbl1,Cebpd,Gfi1,Cdkn1a,Hdac1,Ccnd1,Myc,Cflar,Pdgfrb,Irf8,Ccl5,Max |
| 2.855e-03 | -5.86 | ER-Phagosome pathway | REACTOME pathways | R-MMU-1236974 | 42 | 10 | 8608 | 757 |
H2-T24,H2-Q6,H2-Q7,Tapbp,Tap2,H2-T22,H2-Q4,H2-M2,Tap1,H2-T10 |
| 2.872e-03 | -5.85 | fatty acid derivative biosynthetic process | biological process | GO:1901570 | 45 | 9 | 20694 | 1406 |
Syk,Sphk1,Acsl1,Edn1,Cd74,Ptges,Acsl5,Pla2g4a,Ptgs2 |
| 2.872e-03 | -5.85 | cellular detoxification | biological process | GO:1990748 | 45 | 9 | 20694 | 1406 |
Prdx1,Selenow,Prdx5,Nqo1,Srxn1,Sod2,Hp,S100a8,Esd |
| 2.872e-03 | -5.85 | regulation of pri-miRNA transcription by RNA polymerase II | biological process | GO:1902893 | 45 | 9 | 20694 | 1406 |
Nr3c1,Pdgfb,Stat3,Hif1a,Jun,Fos,Il10,Nfkb1,Bmp2 |
| 2.872e-03 | -5.85 | execution phase of apoptosis | biological process | GO:0097194 | 45 | 9 | 20694 | 1406 |
Casp3,Plscr1,Casp4,Dnase1l3,Casp7,Xkr8,Casp2,Casp1,Casp8 |
| 2.872e-03 | -5.85 | GO_POSITIVE_REGULATION_OF_CELL_CYCLE_ARREST | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_CYCLE_ARREST | 77 | 14 | 15632 | 1249 |
Btg2,Crlf3,Tnks1bp1,Casp2,Cdkn1a,Mdm2,Cnot4,Pml,Plk3,Atm,Cenpj,Cdk5r1,Plk2,Plagl1 |
| 2.891e-03 | -5.85 | CEBPB_01 | MSigDB lists | CEBPB_01 | 240 | 32 | 15632 | 1249 |
Errfi1,Glipr2,Cept1,Pla2g4a,Pde1b,P2ry13,Dusp1,Tnf,Crim1,Pdgfc,Rgs3,Mcmbp,Gys1,Kdm4a,Slc39a13,Nrp2,Il10,Tnfsf14,Ptch1,Lmo4,H3f3b,Il1b,Acsl5,Pim1,Trib1,Rcan1,Gpr85,Adrb2,C3,Ptgir,Scyl2,Itga5 |
| 2.894e-03 | -5.85 | Ig_sub | interpro domains | IPR003599 | 377 | 42 | 19984 | 1430 |
Kdr,Treml2,Vcan,Mfap3l,Igsf8,Milr1,Nectin2,Pdgfrb,Sema4c,Siglece,Il18rap,Flt1,Gm5150,Icosl,Malt1,Axl,Cd80,Trem1,Treml4,Tapbpl,Icam1,A530064D06Rik,Clmp,Cd200,Cd300e,Slamf9,B430306N03Rik,F11r,Fcgr4,Fcgr2b,Fcgr1,Cd300lf,Palld,Tarm1,Sema3c,Cd200r4,Pvr,Cd274,Igsf9,Nectin4,Cd83,Vcam1 |
| 2.897e-03 | -5.84 | GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP | MSigDB lists | GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP | 183 | 26 | 15632 | 1249 |
Aim2,Nck1,Mcoln2,Fam133b,Arl4a,Gnb4,Eno1,D1Ertd622e,Sat1,Dusp2,Carhsp1,B3gnt5,Usp31,Stat1,Uchl1,Fam111a,Esd,Hsd17b7,Mthfd1l,Csrp1,Dusp6,Lap3,Gbp7,Casp8,Slc7a5,Cd69 |
| 2.897e-03 | -5.84 | GSE360_DC_VS_MAC_DN | MSigDB lists | GSE360_DC_VS_MAC_DN | 183 | 26 | 15632 | 1249 |
Ifi209,Ifi205,Hivep2,Ifi213,Cp,Ifi214,Plk3,Atf3,Ifi207,Daxx,Me1,Prdx1,Cd14,Mndal,Ogfr,Irf7,Nfkb1,Maff,Ifi203,Oas2,Ifi211,Psme2,Ifi208,Slc7a5,Ifi204,Ldha |
| 2.897e-03 | -5.84 | GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_DN | MSigDB lists | GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_DN | 183 | 26 | 15632 | 1249 |
Maff,Ksr1,Tmeff1,Plscr1,Irf8,Fam162a,Wdr43,Nfil3,Il1rn,Slc29a3,Ldha,Mdm2,Dock10,Irgm2,Cish,Cd40,Tpst1,Dnaja1,Spryd7,Srm,Agrn,Txnrd1,Slc16a1,Pnpt1,Tmtc2,Nfkbiz |
| 2.897e-03 | -5.84 | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | 183 | 26 | 15632 | 1249 |
Rsbn1,Cldnd1,Ldlr,Chd9,Il15ra,Pf4,Trib1,Odc1,Ptafr,Inpp5b,Stxbp3,Usp12,Spint2,Txn1,Traf5,Zbtb5,Sla,Mdfic,Phip,Tab2,Nxf1,Slc30a1,Arl4a,Ikzf1,Dock4,Cd40 |
| 2.897e-03 | -5.84 | GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_UP | 183 | 26 | 15632 | 1249 |
Marcksl1,Socs1,Clec4e,Insl6,Slc2a1,Ets2,Egr2,Cish,Kdm5b,Cox17,Sema4c,Mmp9,Socs3,Itpkc,Adora2b,Ptgs2,Il1rn,Adam19,Dnajb2,Cdkn1a,Ccr1,Gdf15,Il10,Hdc,Srxn1,Mmd |
| 2.897e-03 | -5.84 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP | 183 | 26 | 15632 | 1249 |
Lyn,Plcl2,Adam19,Daam1,Ccne1,Jag1,Mmd,Rasgrp1,Syne2,Trim26,Zfp36,Kmo,Cd180,Plagl1,Cdkn2d,Rhoh,Cd38,Hck,Gpr18,Dpy19l1,Rapgef5,Apobec3,Ap3b1,Tbc1d1,Irf4,Fchsd2 |
| 2.900e-03 | -5.84 | glycerolipid metabolic process | biological process | GO:0046486 | 281 | 32 | 20694 | 1406 |
Cish,Lipe,Dgkh,Socs7,Cav1,Plpp1,Pla2g7,Pdgfrb,Sirt1,Lipg,Lpcat2,Mppe1,Plaat3,Inpp1,Pgap2,Acsl1,Socs3,Mecp2,Atm,Socs1,Inpp5b,Cept1,Plscr1,Gk,Plek,Pigv,Pgs1,Etnk1,Pik3cd,Pla2g4a,Dgka,Pikfyve |
| 2.917e-03 | -5.84 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | biological process | GO:0070059 | 37 | 8 | 20694 | 1406 |
Trib3,Casp4,Ero1l,Apaf1,Pml,Pmaip1,Itpr1,Casp3 |
| 2.917e-03 | -5.84 | phagocytosis, engulfment | biological process | GO:0006911 | 37 | 8 | 20694 | 1406 |
Fcgr2b,Xkr8,Rac3,Marco,Msr1,Treml4,Fcgr1,Thbs1 |
| 2.923e-03 | -5.84 | LUI_THYROID_CANCER_CLUSTER_1 | MSigDB lists | LUI_THYROID_CANCER_CLUSTER_1 | 46 | 10 | 15632 | 1249 |
Phip,Fosb,Nr4a1,Hhex,Dusp6,Lrp4,Ccnd1,Cebpd,Btg2,St3gal5 |
| 2.923e-03 | -5.84 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_DN | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_DN | 46 | 10 | 15632 | 1249 |
H2-Ab1,Kat2b,P2ry14,Hdc,Casp8,Btg2,Irf4,Rnf24,Sdc2,Fgl2 |
| 2.936e-03 | -5.83 | CEBP_Q3 | MSigDB lists | CEBP_Q3 | 221 | 30 | 15632 | 1249 |
Bcl6,Jun,Mid1,Ccr3,Pla2g4a,Nfkbiz,Palld,Rab3ip,Etv5,Spred1,Lipg,Gys1,Asah2,Lmo4,Pdgfrb,Junb,Jarid2,Brd2,Ube2e2,Syne2,Pdgfb,Med13,Chic2,Cd55,Dgkh,Kpna3,Tagap,Acsl5,Kitl,Tnfsf10 |
| 2.937e-03 | -5.83 | Thyroid hormone signaling pathway | KEGG pathways | mmu04919 | 115 | 20 | 7931 | 713 |
Pik3cd,Hdac1,Myc,Map2k1,Notch1,Hif1a,Dio2,Notch2,Ccnd1,Actb,Slc9a1,Slc2a1,Kat2b,Med13,Stat1,Akt3,Mdm2,Src,Itgav,Rcan1 |
| 2.945e-03 | -5.83 | GO_GUANYL_NUCLEOTIDE_BINDING | MSigDB lists | GO_GUANYL_NUCLEOTIDE_BINDING | 339 | 42 | 15632 | 1249 |
Rhof,Rab32,Ehd1,Pde5a,Rab21,Irgm2,Irgq,Rab9,Gbp4,Gbp9,Rhoq,Rab19,Nkiras1,Rnd1,Gbp3,Arl4a,Gmppb,Tpx2,Rhoh,Gbp2,Rhoc,Samhd1,Ciita,Rnd3,Rras2,Gna15,Gem,Gbp7,Gch1,Tuba4a,Rapgef2,Rhou,Rab10,Arl5b,Ak4,Rab20,Arl5c,Rac3,Gtpbp2,Arf4,Gbp2b,Rap2c |
| 2.949e-03 | -5.83 | Toll_tir_struct_dom_sf | interpro domains | IPR035897 | 28 | 7 | 19984 | 1430 |
Tlr6,Tlr2,Tlr9,Tlr1,Myd88,Il18rap,Tlr3 |
| 2.951e-03 | -5.83 | organelle envelope | cellular component | GO:0031967 | 1018 | 92 | 20747 | 1409 |
Sirt1,Syne2,Bnip3,Snn,Glrx,Ankrd17,Bcl2a1b,Ppp1r15a,Slc25a37,Cnp,Trib3,Chmp4b,Armcx6,Ptges,Pml,Tspo,Slc30a1,Pnpt1,Vrk2,Gja1,1600014C10Rik,Gk,Rsad2,Dtx2,Plekhn1,Gch1,Slc44a1,Ccnd2,Phf11c,Hk1,Nxf1,Cox18,Stat3,Dync1h1,Adap2,Ikbke,Slc16a3,Parp11,Nr4a1,Agpat4,AA467197,Trim14,Prnp,Phf11a,Mx1,Smox,Ass1,Sh3bgrl2,Dpy19l1,Src,Phf11b,Lyn,Gpd2,Kmo,Phlpp1,Ranbp2,Phf11d,Rmdn3,Tomm70a,Bcl2a1a,Hk2,Slc25a12,Acsl5,Uaca,Slc25a25,Prpf38a,Tent4a,Pcx,Mx2,Sco1,Cox17,Acsl1,Mul1,Ptger4,Rab32,Cacybp,Myc,Osbpl3,Higd1a,Dnajb2,Sod2,Ednrb,Itpr1,Rap1gap2,Dusp2,Tor3a,Slc25a22,Bcl2a1d,Dst,Tor1aip1,Cycs,Fgr |
| 2.965e-03 | -5.82 | GSE3982_MAC_VS_NEUTROPHIL_LPS_STIM_UP | MSigDB lists | GSE3982_MAC_VS_NEUTROPHIL_LPS_STIM_UP | 174 | 25 | 15632 | 1249 |
Tcf4,Slc39a4,Ifi44,Cers6,Acvrl1,Atf3,Mcm10,Stxbp1,Rtp4,Tspo,Abtb2,Sik3,Fubp1,Serpine1,Slc39a14,Oas1a,Fndc3a,Oas1g,Dck,Kcna3,Aida,Gpd2,Arid5b,Rgs1,Wdr43 |
| 2.965e-03 | -5.82 | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | 174 | 25 | 15632 | 1249 |
Fam20c,Igf2bp2,Dennd2a,Traf3ip2,Mtdh,Ptk2,Slamf8,Ak4,H2-Aa,Dcun1d3,Pbx1,Samhd1,Gbp2,Clcn5,Palld,Sphk1,Nxf1,Cd74,Etv3,Il1a,Slc7a11,Plod3,Map3k6,Tiparp,Itpr1 |
| 2.965e-03 | -5.82 | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | 174 | 25 | 15632 | 1249 |
Mapkapk2,Cyth3,Agtrap,Nod1,Rhoc,Spn,Parp8,Itgav,Plekha5,N4bp1,Sp140,Prkce,Dennd1b,Egr3,Fcho2,Slc25a22,Cflar,Chd9,Thbs1,Gfi1,Tnfsf14,Lcp2,Tmeff1,Trim14,Stat4 |
| 2.965e-03 | -5.82 | GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_UP | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_UP | 174 | 25 | 15632 | 1249 |
Il6,Nr3c1,Zyx,Sqstm1,Bcl2l11,Flt1,Ppfibp1,Pfkfb3,Plagl1,Mxd1,Prdm1,Dcp1a,St3gal5,Akt3,Tnfsf14,Tnfrsf1b,Rabgef1,Acsl5,Cmklr1,Azi2,Mefv,Dyrk2,Rnf19b,Kdm6b,Etnk1 |
| 2.965e-03 | -5.82 | GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_UP | MSigDB lists | GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_UP | 174 | 25 | 15632 | 1249 |
Hk3,Bmp2,Sla,Extl2,Sell,Socs1,Ifih1,P2ry14,Prnp,Palld,Mid1,Rsad2,Rhoq,Bcl2l11,Gfi1,Acp2,Nfil3,Whamm,Il1rn,Spint2,Kctd12,H2-Aa,Myo1b,Sema3c,Slc4a7 |
| 2.965e-03 | -5.82 | GSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_UP | 174 | 25 | 15632 | 1249 |
Txnrd1,S100a8,Rab32,Slc7a8,P2ry13,Adap2,Fzd5,Fchsd2,Pla2g4a,Sat1,Csf1,1110038F14Rik,Ppp2r3a,Il13ra1,C3,Stxbp1,Ube2e1,Frmd4a,Ccl22,Kmo,Plau,Cd83,Clcn7,Me1,Fam162a |
| 2.977e-03 | -5.82 | GO_CELLULAR_CHEMICAL_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_CHEMICAL_HOMEOSTASIS | 535 | 61 | 15632 | 1249 |
Hk2,Atp6v1d,Gja1,Ccl5,Ccr1,Slc31a2,Slc4a7,Il1b,Htr2b,Clic4,Grina,Hmox1,Slc31a1,Ptger4,Cd55,Atp13a1,Slc39a4,Cp,Cd40,Swap70,Itpr1,Cd38,Sgk3,Icam1,Hif1a,Slc39a13,Pml,Sirt1,Slc39a14,Slc9a1,Lcn2,P2ry2,Sco1,Cav1,Gna15,Ednrb,Hk1,S100a8,Pdk3,Xcr1,Jak2,Rab20,Mafg,Lpar1,Cacnb3,Nox1,Prkce,Myc,Ccl2,Edn1,Ccr3,Kcnj2,Ccl12,Atp2b4,Hk3,Htr2a,Plau,Slc30a1,Irs2,Prnp,Fas |
| 2.980e-03 | -5.82 | fructokinase activity | molecular function | GO:0008865 | 5 | 3 | 20217 | 1400 |
Hk3,Hk2,Hk1 |
| 2.980e-03 | -5.82 | glucokinase activity | molecular function | GO:0004340 | 5 | 3 | 20217 | 1400 |
Hk1,Hk2,Hk3 |
| 2.980e-03 | -5.82 | C-X3-C chemokine binding | molecular function | GO:0019960 | 5 | 3 | 20217 | 1400 |
Itgav,Itga4,Cx3cr1 |
| 2.980e-03 | -5.82 | hexokinase activity | molecular function | GO:0004396 | 5 | 3 | 20217 | 1400 |
Hk3,Hk1,Hk2 |
| 2.980e-03 | -5.82 | activin-activated receptor activity | molecular function | GO:0017002 | 5 | 3 | 20217 | 1400 |
Acvr1,Acvr1b,Acvrl1 |
| 2.980e-03 | -5.82 | mannokinase activity | molecular function | GO:0019158 | 5 | 3 | 20217 | 1400 |
Hk2,Hk1,Hk3 |
| 2.980e-03 | -5.82 | stem cell factor receptor binding | molecular function | GO:0005173 | 5 | 3 | 20217 | 1400 |
Spred3,Kitl,Spred1 |
| 2.995e-03 | -5.81 | Acute myeloid leukemia | KEGG pathways | mmu05221 | 55 | 12 | 7931 | 713 |
Ikbkg,Stat3,Ccnd1,Pml,Myc,Map2k1,Pik3cd,Akt3,Pim2,Stat5a,Nfkb1,Pim1 |
| 2.995e-03 | -5.81 | Acute myeloid leukemia | KEGG pathways | ko05221 | 55 | 12 | 7931 | 713 |
Pim2,Stat5a,Akt3,Pim1,Nfkb1,Ccnd1,Stat3,Ikbkg,Map2k1,Myc,Pik3cd,Pml |
| 2.996e-03 | -5.81 | Kinase-like_dom_sf | interpro domains | IPR011009 | 526 | 55 | 19984 | 1430 |
Vrk2,Lyn,Tlk2,Igf1r,Sik3,Eif2ak2,Acvr1,Map2k4,Trib3,Mapkapk2,Ripk2,Acvr1b,Ksr1,Pik3cd,Syk,Pim3,Axl,Ptk2,Prkx,Scyl2,Mlkl,Prag1,Akt3,Kdr,Irak2,Met,Map3k6,Dyrk2,Grk3,Prkce,Hck,Plk2,Trib1,Atm,Ripk3,Jak2,Map2k1,Acvrl1,Ikbke,Nek6,Pim2,Tyk2,Fgr,Irak3,Stk40,Sgk3,Pim1,Plk3,Map3k8,Mark2,Etnk1,Pdgfrb,Src,Map4k4,Flt1 |
| 3.000e-03 | -5.81 | TBK1.DF_DN | MSigDB lists | TBK1.DF_DN | 260 | 34 | 15632 | 1249 |
Dennd1b,Rai14,Spry2,Ccng2,Ccnd1,Flrt3,Ifit1bl1,Psmb9,Fos,Klf7,Irf2,Ddx60,Kdm4a,Dcp2,Ccnd2,Gja1,Psmb8,Ifit1bl2,Plekha2,Lmo4,Sema3c,Thbs1,Il1rn,Osbpl3,Ptges,Pmepa1,Pkp4,Tmod3,Smc5,Dck,Ell2,Etnk1,Hmgcs1,Nsmaf |
| 3.010e-03 | -5.81 | NAKAMURA_ADIPOGENESIS_LATE_UP | MSigDB lists | NAKAMURA_ADIPOGENESIS_LATE_UP | 94 | 16 | 15632 | 1249 |
Plk3,Atf3,Hmgcs1,Irs2,Serpinb9,Acsl5,Ppp2r1b,Prkar2b,Nfil3,Lipe,Myadm,Myc,Ppp2r5a,Ccrl2,Mmd,Cebpd |
| 3.010e-03 | -5.81 | GO_POSITIVE_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 94 | 16 | 15632 | 1249 |
Rnf19b,Plk3,Smc5,Trib1,Trib3,Gclc,Keap1,Dnajb2,Ankib1,Rnf114,Rnf14,Cav1,Plk2,Psmd10,Rnf19a,Mdm2 |
| 3.014e-03 | -5.80 | GO_PROTEIN_KINASE_B_SIGNALING | MSigDB lists | GO_PROTEIN_KINASE_B_SIGNALING | 32 | 8 | 15632 | 1249 |
Plk3,Tnf,Axl,Ccl12,Ccl5,P2ry12,Il1b,Cd40 |
| 3.014e-03 | -5.80 | GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION | 32 | 8 | 15632 | 1249 |
Il10,Klf2,Tnf,Tlr9,Rabgef1,Zc3h12a,Irak3,Tnfaip3 |
| 3.014e-03 | -5.80 | MOOTHA_GLUCONEOGENESIS | MSigDB lists | MOOTHA_GLUCONEOGENESIS | 32 | 8 | 15632 | 1249 |
Eno1,Gpd2,Ldha,Tpi1,Eno2,Pcx,Me1,Pgk1 |
| 3.014e-03 | -5.80 | GO_POSITIVE_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | 32 | 8 | 15632 | 1249 |
Src,Ccnd2,Pim1,Psmd10,Pdgfb,Cdkn1a,Hspa2,Ccnd1 |
| 3.014e-03 | -5.80 | GO_T_CELL_PROLIFERATION | MSigDB lists | GO_T_CELL_PROLIFERATION | 32 | 8 | 15632 | 1249 |
Cd86,Tnfsf14,Psmb10,Malt1,Ebi3,Tnfsf4,Ripk2,Il15 |
| 3.023e-03 | -5.80 | response to heat | biological process | GO:0009408 | 100 | 15 | 20694 | 1406 |
Osm,Dnaja2,Daxx,Il1a,Hmox1,Dnaja1,Psip1,Hspa2,Lrp11,Hspa1a,Tfec,Gclc,Pde4b,Hspa1b,Ccl2 |
| 3.023e-03 | -5.80 | GSE32901_TH1_VS_TH17_ENRICHED_CD4_TCELL_UP | MSigDB lists | GSE32901_TH1_VS_TH17_ENRICHED_CD4_TCELL_UP | 165 | 24 | 15632 | 1249 |
Nr3c1,Peli1,Rab11fip1,Ythdf1,Phip,Fam133b,Sell,Traf1,Crim1,Zc3hav1,Olfml3,Casp8,Sipa1l1,Zeb1,Ext1,Med13,Stat4,Dgka,Fcho2,Pim1,Rcsd1,Znrf1,Plcl2,Tax1bp1 |
| 3.023e-03 | -5.80 | GO_REGULATION_OF_CELL_SUBSTRATE_ADHESION | MSigDB lists | GO_REGULATION_OF_CELL_SUBSTRATE_ADHESION | 165 | 24 | 15632 | 1249 |
Vegfc,Thbs1,Kdr,Gcnt2,Jak2,Rac3,Itga5,Ptk2,Ptprj,Csf1,Slc9a1,Plekha2,Serpine1,Myadm,Hsd17b12,Notch1,Plau,Sdc4,Acvrl1,Triobp,Prkce,Mmp14,Bcl6,Src |
| 3.023e-03 | -5.80 | GO_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS | 165 | 24 | 15632 | 1249 |
Psme1,Nr1h3,Irs2,Psmb10,Fabp3,Kat2b,Bmp2,Atp2b4,Psmb9,Psmd10,Prkce,Pla2g4a,Nqo1,Psma6,Psmb6,Nr4a3,Trib3,Ptgs2,Odc1,Psmb8,Pdk3,Cav1,Psme2,Sirt1 |
| 3.023e-03 | -5.80 | GSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_UP | MSigDB lists | GSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_UP | 165 | 24 | 15632 | 1249 |
Mapkbp1,Smg7,Marcksl1,Aim2,Lrp8,Ccl22,Sat1,Slc44a1,Tmem184b,Zyx,Cflar,Serpinb2,Dnajb2,Acvr1b,Mthfd2,Icosl,Reps1,Pdlim7,Mmd,Slc7a8,Dusp6,Vezt,Vps54,Dmwd |
| 3.023e-03 | -5.80 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_UP | 165 | 24 | 15632 | 1249 |
Gng11,Cd34,Mdfic,Mapkapk2,Tmem176b,Il4ra,Ctsc,Ikzf1,Phactr4,Lztfl1,Ifnar1,Morc3,Ankrd17,Rgs1,Prkx,Tmod3,Nr4a3,Aida,Ptgs2,Pdss1,Junb,Plekha2,Plod2,Fosb |
| 3.023e-03 | -5.80 | GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_DN | MSigDB lists | GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_DN | 165 | 24 | 15632 | 1249 |
Mtus1,Bcl6,Phlpp1,Treml2,Glipr2,I830077J02Rik,Scarf1,Trp53i11,Ccdc88b,Smg7,Atp11b,Ttc9c,4930523C07Rik,Tuba4a,Sh3bp4,Vasp,Casp2,Ldha,Adora2b,Il2rg,Cflar,Stard7,Cmpk2,Lrrc8c |
| 3.035e-03 | -5.80 | envelope | cellular component | GO:0031975 | 1019 | 92 | 20747 | 1409 |
Phf11c,Ccnd2,Nxf1,Hk1,Stat3,Cox18,Gk,1600014C10Rik,Rsad2,Dtx2,Gch1,Slc44a1,Plekhn1,Trim14,AA467197,Mx1,Phf11a,Prnp,Smox,Src,Phf11b,Sh3bgrl2,Dpy19l1,Ass1,Dync1h1,Parp11,Adap2,Ikbke,Slc16a3,Agpat4,Nr4a1,Glrx,Ankrd17,Syne2,Sirt1,Snn,Bnip3,Slc30a1,Pnpt1,Pml,Tspo,Vrk2,Gja1,Bcl2a1b,Slc25a37,Ppp1r15a,Chmp4b,Cnp,Trib3,Ptges,Armcx6,Ednrb,Sod2,Dusp2,Rap1gap2,Itpr1,Tor3a,Rab32,Ptger4,Myc,Cacybp,Dnajb2,Osbpl3,Higd1a,Tor1aip1,Dst,Fgr,Cycs,Slc25a22,Bcl2a1d,Rmdn3,Phf11d,Bcl2a1a,Tomm70a,Hk2,Slc25a12,Kmo,Gpd2,Lyn,Phlpp1,Ranbp2,Mul1,Acsl1,Cox17,Sco1,Acsl5,Tent4a,Pcx,Prpf38a,Uaca,Slc25a25,Mx2 |
| 3.036e-03 | -5.80 | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_UP | MSigDB lists | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_UP | 193 | 27 | 15632 | 1249 |
Il1rn,Zhx2,Stip1,Uchl1,Psmb6,Kif3c,Ifi204,Ifi208,Ifi211,Trim21,Ifi203,Rnf14,Nfkb1,Irf7,Mndal,Mapkbp1,Daxx,Ifi207,Aldh1b1,Ifi214,Igsf6,Cp,Abcb1a,Pcx,Ifi213,Ifi205,Ifi209 |
| 3.038e-03 | -5.80 | MHC protein binding | molecular function | GO:0042287 | 29 | 7 | 20217 | 1400 |
Klrk1,Tap1,Pilrb1,Tap2,Pilrb2,Pilra,Cd74 |
| 3.038e-03 | -5.80 | cyclic-nucleotide phosphodiesterase activity | molecular function | GO:0004112 | 29 | 7 | 20217 | 1400 |
Prkar2b,Pde5a,Pde1b,Cnp,Pde3b,Pde4b,Pde7b |
| 3.046e-03 | -5.79 | WOOD_EBV_EBNA1_TARGETS_DN | MSigDB lists | WOOD_EBV_EBNA1_TARGETS_DN | 39 | 9 | 15632 | 1249 |
Idi1,Tax1bp1,Abcc4,Il13ra1,Psmb8,Sphk1,Adap2,Tgfbi,Ptgs2 |
| 3.046e-03 | -5.79 | chr11q22 | MSigDB lists | chr11q22 | 39 | 9 | 15632 | 1249 |
Tmem123,Ppp2r1b,Mmp13,Atm,Birc3,Il18,Birc2,Casp4,Zc3h12c |
| 3.046e-03 | -5.79 | GO_PHOSPHATASE_COMPLEX | MSigDB lists | GO_PHOSPHATASE_COMPLEX | 39 | 9 | 15632 | 1249 |
Ppp4r2,Ppp2r5a,Cycs,Ppp2r3a,Ppp2r2a,Ppp1r15b,Nck1,Itpr1,Ppp1r15a |
| 3.046e-03 | -5.79 | GO_TRANSITION_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_TRANSITION_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 39 | 9 | 15632 | 1249 |
Slc39a14,Slc39a13,Atp13a1,Slc30a1,Slc25a37,Slc31a2,Slc30a4,Slc39a4,Slc31a1 |
| 3.046e-03 | -5.79 | ZHAN_EARLY_DIFFERENTIATION_GENES_DN | MSigDB lists | ZHAN_EARLY_DIFFERENTIATION_GENES_DN | 39 | 9 | 15632 | 1249 |
Ccng2,Myc,Ciita,Traf5,Il4ra,Rel,Rhoh,Egr3,Tnf |
| 3.049e-03 | -5.79 | ARID_dom | interpro domains | IPR001606 | 15 | 5 | 19984 | 1430 |
Arid5a,Jarid2,Arid5b,Kdm5b,Arid4a |
| 3.049e-03 | -5.79 | ARID_dom_sf | interpro domains | IPR036431 | 15 | 5 | 19984 | 1430 |
Arid5a,Jarid2,Arid5b,Kdm5b,Arid4a |
| 3.049e-03 | -5.79 | CCTGCTG_MIR214 | MSigDB lists | CCTGCTG_MIR214 | 212 | 29 | 15632 | 1249 |
Slc7a8,Vezt,Rims3,Csf1,Rtn2,Atxn7l1,Vasn,Adora2a,Rap1gap2,Fam53c,Cpeb4,Larp1,Crkl,Kpna3,Acvr1b,Phf6,Pim1,Gpr85,Pcdh7,Socs7,Slc16a3,Arid5a,Trip10,Mid1,Fam133b,Chmp4b,Mark2,Atp2b4,Plagl2 |
| 3.054e-03 | -5.79 | MODULE_378 | MSigDB lists | MODULE_378 | 370 | 45 | 15632 | 1249 |
Sema4a,Acsl1,Mmp9,Nfil3,Clcf1,Chd9,Plekhg1,Gem,Lap3,Csf1,Trim14,Ppp4r2,Timeless,Phip,Fpr2,Kat2b,Ddx60,Zbtb5,Slamf7,Fos,Cited2,Hivep2,Morc3,Ccl12,Mmp14,Ptgs2,Cxcl10,Larp1,Gja1,Tuba4a,Il1a,Hif1a,Prdm1,Itga4,Ncoa7,Mcmbp,Sav1,Mapkbp1,Smg7,Arid5a,Plekhf2,Kdm5b,Acvr1,Gpr68,Stat3 |
| 3.068e-03 | -5.79 | NABA_MATRISOME | MSigDB lists | NABA_MATRISOME | 924 | 97 | 15632 | 1249 |
Clec4n,P4ha1,Ltbp2,Il10,Tnfsf14,Htra1,Tnfsf4,Ebi3,Sema4a,Clcf1,Fam20c,Ccl12,Agrn,Il6,Ccl2,Sdc2,Cxcl14,Ccl22,Plau,Ifna1,Angpt1,Lgals9,Pdgfb,Tnfsf15,Ifna6,Csf3,Clec5a,Tgfbi,Clec4d,Il12b,Cxcl10,Lox,Serpinb9,Il1rn,Thbs1,Tnfsf10,Serpinb2,Vegfc,Pf4,Cst7,Insl6,Timp1,Lif,Il1a,Crlf3,Bmp2,Crim1,S100a8,Sema3c,Plod2,Csf1,Slpi,Egln3,Sema4c,Mmp9,Mmp25,Adam19,Col27a1,Ccl4,Ctsc,Mmp14,Vcan,Ifnb1,Ifna5,Col18a1,Sdc1,Cx3cl1,Il15,F10,Sdc4,Col4a2,Clec4e,Gpc1,Gdf15,Ccl5,Col11a2,Osm,Serpine1,Mmp13,Inhba,Cxcl2,Il18,Cxcl1,Plat,Kitl,Il1b,P4ha2,Tnf,Plod3,Tnc,Ntng2,Tnfsf8,Fgl2,Pdgfc,Ccl3,Tsku,Ifna2 |
| 3.076e-03 | -5.78 | gland morphogenesis | biological process | GO:0022612 | 120 | 17 | 20694 | 1406 |
Stat5a,Cav1,Notch2,Csf1,Tnf,Igf1r,Pdgfb,Il6,Tnc,Ptch1,Tet2,Pml,Notch1,Kdm5b,Nr3c1,Sema3c,Src |
| 3.089e-03 | -5.78 | ALK_DN.V1_UP | MSigDB lists | ALK_DN.V1_UP | 129 | 20 | 15632 | 1249 |
Asns,Gna15,Psat1,Gdf15,Slc7a11,Nod2,Bst1,Ddit4,Il6,Slc7a5,Trib3,Mthfd2,Prdm1,Nfkbil1,Ch25h,Vegfc,Trem1,Tfec,Olfml3,Slamf7 |
| 3.104e-03 | -5.78 | K63-linked polyubiquitin modification-dependent protein binding | molecular function | GO:0070530 | 22 | 6 | 20217 | 1400 |
Tab2,Tnfaip3,Optn,Parp10,Sqstm1,Ikbkg |
| 3.104e-03 | -5.78 | nitric-oxide synthase binding | molecular function | GO:0050998 | 22 | 6 | 20217 | 1400 |
Nos2,Atp2b4,Actb,Cd74,Cav1,Arg2 |
| 3.105e-03 | -5.77 | GO_CELLULAR_RESPONSE_TO_RADIATION | MSigDB lists | GO_CELLULAR_RESPONSE_TO_RADIATION | 138 | 21 | 15632 | 1249 |
Hif1a,Ifi204,Ptgs2,Ifi214,Egr1,Ifi207,Cdkn1a,Ppp1r15a,Ifi205,Mndal,Ifi209,Ifi213,Atm,N4bp1,Sirt1,Tlk2,Mdm2,Ifi203,Ifi211,Ifi208,Myc |
| 3.105e-03 | -5.77 | GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_UP | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_UP | 138 | 21 | 15632 | 1249 |
Dse,Gpr18,Card6,Pde4b,Ifnb1,Il18rap,Ube2e2,Stard5,Ctsc,Akt3,Bnip3,Sell,Mafg,Pigv,Cyth3,Dyrk2,Evl,Slfn5,Mob3c,Tnfrsf14,Ikbke |
| 3.105e-03 | -5.77 | Glucose metabolism | REACTOME pathways | R-MMU-70326 | 71 | 14 | 8608 | 757 |
Slc25a12,Pcx,Hk3,Pfkl,Hk2,Hk1,Pfkfb3,Gbe1,Pgm1,Eno1,Gys1,Tpi1,Eno2,Pgk1 |
| 3.111e-03 | -5.77 | regulation of sensory perception | biological process | GO:0051931 | 54 | 10 | 20694 | 1406 |
Adrb2,Cacnb3,Slc9a1,Ptafr,Ednrb,Fcgr4,Edn1,Il10,Acpp,Il1a |
| 3.118e-03 | -5.77 | MODULE_179 | MSigDB lists | MODULE_179 | 401 | 48 | 15632 | 1249 |
Gja1,Tuba4a,Larp1,Ptgs2,Cxcl10,Plekhf2,Arid5a,Stat3,Acvr1,Kdm5b,Gpr68,Itga4,Prdm1,Hif1a,Il1a,Mapkbp1,Sav1,Smg7,Ncoa7,Mcmbp,Plekhg1,Lap3,Gem,Trim14,Csf1,Ppp4r2,Timeless,Tnfsf4,Mmp9,Il13ra1,Acsl1,Sema4a,Clcf1,Chd9,Nfil3,Morc3,Hivep2,Ccl12,Fos,Cited2,Mmp14,Ddx60,Kat2b,Fpr2,Phip,Aldh1b1,Zbtb5,Slamf7 |
| 3.124e-03 | -5.77 | GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_UP | 184 | 26 | 15632 | 1249 |
Cish,Cxcl14,Ankrd24,Syk,Clcn5,Gda,Tnfaip3,Mxd1,Icam1,Fpr2,Arg2,Ccrl2,Kctd12,S100a8,Dusp6,Gbp7,Col27a1,Ppfibp2,Hp,Dram1,Mmp9,Hmox1,Gng4,Pim1,Pdzd11,Lyn |
| 3.124e-03 | -5.77 | GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 184 | 26 | 15632 | 1249 |
Gbp3,Atp11a,Ier2,Nqo1,Psip1,Lipe,Cenpe,Spsb1,Igf1r,Tax1bp1,Serpinb2,Tgfbi,Adora2b,Irf1,Hk2,Il12rb1,Flnb,Phlda1,Ppp4r2,Ddit4,Zeb1,Casp4,Plk2,Irf8,Ccr1,Dach1 |
| 3.124e-03 | -5.77 | RAF_UP.V1_DN | MSigDB lists | RAF_UP.V1_DN | 184 | 26 | 15632 | 1249 |
Ak4,Gpd2,Egr3,Pkp4,Igf1r,Zhx2,Jak2,Bambi,Kitl,Myo1b,Cav1,Plk2,Slc7a2,Pdk3,Rasgrp1,Ddit4,Palld,Myo10,Rnd3,Slc16a1,Tspan3,Fos,Ccnd1,Sdc2,Ift57,Minpp1 |
| 3.124e-03 | -5.77 | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_DN | 184 | 26 | 15632 | 1249 |
Uba7,Stx6,Il12rb1,Smpdl3b,Irf7,Nfkb1,Psat1,Nfil3,Znrf1,Spata5l1,Dhx58,Cebpd,Hdac1,Il18bp,Glipr2,1110038F14Rik,Irf4,Phgdh,Abcb1a,D16Ertd472e,Arid5a,Tap1,Ifit1,Ripk3,Slc48a1,Lrp8 |
| 3.140e-03 | -5.76 | ARID | pfam domains | PF01388 | 15 | 5 | 18711 | 1348 |
Jarid2,Kdm5b,Arid5b,Arid4a,Arid5a |
| 3.146e-03 | -5.76 | PIP3 activates AKT signaling | REACTOME pathways | R-MMU-1257604 | 110 | 19 | 8608 | 757 |
Kitl,Cdkn1a,Pdgfb,Mdm2,Met,Ier3,Rictor,Phlpp1,Src,Trib3,Phlpp2,Ppp2r5a,Cd80,Irs2,Pik3cd,Pdgfrb,Ppp2r1b,Cd86,Nr4a1 |
| 3.167e-03 | -5.75 | chr7p15 | MSigDB lists | chr7p15 | 54 | 11 | 15632 | 1249 |
Ahr,Actb,Osbpl3,Nod1,Tax1bp1,Snx10,Rapgef5,Tra2a,Inhba,Ggct,Itgb8 |
| 3.169e-03 | -5.75 | regulation of steroid biosynthetic process | biological process | GO:0050810 | 72 | 12 | 20694 | 1406 |
Il1b,Bmp2,Adora2b,Gfi1,Sirt1,Nr3c1,Egr1,Tnf,Il1a,Tspo,Nfkb1,Igf1r |
| 3.188e-03 | -5.75 | RGAGGAARY_PU1_Q6 | MSigDB lists | RGAGGAARY_PU1_Q6 | 453 | 53 | 15632 | 1249 |
Rilpl1,Vasp,Vasn,Csf3,Map2k1,Samsn1,Lcp2,Plat,Htr2b,Smox,Ptprj,Gpr85,Il12b,Ptafr,Acvrl1,Treml2,Parp8,Src,Stat5a,Tnf,Ccdc88b,Tmc3,Plagl2,Lif,Pml,Hhex,Timeless,Trip13,Csf1,Etv6,Slc39a14,Sik3,Irf8,Itgal,Tnfsf14,Cacna1d,Mob3c,Tmod3,Ptgir,Mmp9,Max,Cpeb4,Rab20,Lyn,Il4i1,Stap1,Pla2g4a,I830077J02Rik,Trmt1l,Psip1,Znfx1,Ahr,Angpt1 |
| 3.196e-03 | -5.75 | regulation of myotube differentiation | biological process | GO:0010830 | 63 | 11 | 20694 | 1406 |
Il4ra,Mmp14,Cflar,Ehd1,Daxx,Notch1,Tnfsf14,Gdf15,Cxcl9,Ccl8,Cxcl10 |
| 3.197e-03 | -5.75 | positive regulation of cell proliferation involved in kidney development | biological process | GO:1901724 | 10 | 4 | 20694 | 1406 |
Egr1,Myc,Pdgfb,Cflar |
| 3.197e-03 | -5.75 | regulation of prostaglandin biosynthetic process | biological process | GO:0031392 | 10 | 4 | 20694 | 1406 |
Sirt1,Il1b,Ptgs2,Pla2g4a |
| 3.197e-03 | -5.75 | T-helper 17 cell differentiation | biological process | GO:0072539 | 10 | 4 | 20694 | 1406 |
Batf,Stat3,Irf4,Il6 |
| 3.197e-03 | -5.75 | T-helper 17 type immune response | biological process | GO:0072538 | 10 | 4 | 20694 | 1406 |
Stat3,Batf,Irf4,Il6 |
| 3.197e-03 | -5.75 | T-helper 1 cell differentiation | biological process | GO:0045063 | 10 | 4 | 20694 | 1406 |
Relb,Gadd45g,Sema4a,Spn |
| 3.197e-03 | -5.75 | regulation of T-helper 2 cell cytokine production | biological process | GO:2000551 | 10 | 4 | 20694 | 1406 |
Nlrp3,Il6,Rsad2,Ifnb1 |
| 3.197e-03 | -5.75 | positive regulation of MHC class II biosynthetic process | biological process | GO:0045348 | 10 | 4 | 20694 | 1406 |
Sirt1,Jak2,Il10,Ciita |
| 3.197e-03 | -5.75 | tyrosine phosphorylation of STAT protein | biological process | GO:0007260 | 10 | 4 | 20694 | 1406 |
Jak2,Il15,Lif,Osm |
| 3.197e-03 | -5.75 | negative regulation of leukocyte degranulation | biological process | GO:0043301 | 10 | 4 | 20694 | 1406 |
Hmox1,Rabgef1,Abr,Lgals9 |
| 3.197e-03 | -5.75 | regulation of interleukin-12 biosynthetic process | biological process | GO:0045075 | 10 | 4 | 20694 | 1406 |
Rel,Nfkb1,Tlr6,Irf1 |
| 3.197e-03 | -5.75 | regulation of natural killer cell mediated cytotoxicity directed against tumor cell target | biological process | GO:0002858 | 10 | 4 | 20694 | 1406 |
Klrk1,Pvr,Nectin2,Il12b |
| 3.204e-03 | -5.74 | GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP | MSigDB lists | GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP | 175 | 25 | 15632 | 1249 |
Flnb,Isg20,Slc9a1,Pou2f2,Bst1,Ednrb,Plek,Psmb8,Pcdh7,Jak2,Cxcl1,Dcbld2,Itga5,Irf1,Itga9,Minpp1,Vcan,Apobec3,Pde3b,Trp53i11,Samhd1,Gbp2,Myo10,Mdfic,Pttg1 |
| 3.204e-03 | -5.74 | PEREZ_TP53_AND_TP63_TARGETS | MSigDB lists | PEREZ_TP53_AND_TP63_TARGETS | 175 | 25 | 15632 | 1249 |
Ptprj,Col27a1,Bambi,Igf1r,Adap2,Ksr1,Vasn,Fzd1,Rasgrp1,Col18a1,Egr1,Bcor,Spata13,Cx3cl1,Arg2,Bmp2,Apaf1,Foxp4,Fam43a,Bcl2l11,Casz1,Micall2,Egr2,Rab11fip1,Cxcl14 |
| 3.204e-03 | -5.74 | GSE3982_DC_VS_TH1_DN | MSigDB lists | GSE3982_DC_VS_TH1_DN | 175 | 25 | 15632 | 1249 |
Pik3cd,Stip1,Gfi1,Cflar,Ccl4,Adam19,Hopx,Nos2,Fubp1,Nampt,Gch1,Slc39a14,Zeb1,Pttg1,Arl4a,Mxd1,Pgs1,Magohb,Sdc4,Tnf,Klf6,Nfkbia,Sp140,Chst11,Hspa2 |
| 3.204e-03 | -5.74 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP | 175 | 25 | 15632 | 1249 |
Cd69,Rap1gap2,Klf2,Rnaset2a,Sik3,Casp8,Fosb,Rnaset2b,Plcl2,Tmem123,Arid5b,Ptger4,Sema4c,Dyrk2,Peli1,Fos,Jun,Tiparp,Dusp1,Plac8,Klf7,Tnfaip3,Arl4a,Nlrp3,Irs2 |
| 3.204e-03 | -5.74 | GSE22589_HEALTHY_VS_SIV_INFECTED_DC_UP | MSigDB lists | GSE22589_HEALTHY_VS_SIV_INFECTED_DC_UP | 175 | 25 | 15632 | 1249 |
Dbnl,Ogfrl1,Rgs14,Jun,Slc2a1,Hspa1a,Batf,Ciita,Ccdc88b,Hvcn1,Atf3,Nfkbil1,Jmjd6,Nlrp3,Il4ra,Rilpl1,Timeless,Hk2,Slc12a9,Jdp2,Cnp,Ldlr,Il1b,Irf1,Nr4a3 |
| 3.204e-03 | -5.74 | GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_DN | MSigDB lists | GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_DN | 175 | 25 | 15632 | 1249 |
Isg20,Stat4,Pde7b,Casp2,Tdrd7,Ifit1bl2,Hsd17b12,Cd300lf,Ifi35,Tlr3,Tgfbi,Frmd4a,Rsad2,Samd9l,Cpd,Cenpe,Ifit1bl1,Sbds,Sla,Lpcat2,Ncoa7,Mcm10,Usp18,Zfp281,Ifih1 |
| 3.236e-03 | -5.73 | nuclear-transcribed mRNA catabolic process | biological process | GO:0000956 | 91 | 14 | 20694 | 1406 |
Magohb,Xrn1,Helz2,Tent2,Atm,Tent4a,Smg7,Polr2g,Zfp36,Noct,Zc3h12a,Dcp1a,Dcp2,Gtpbp2 |
| 3.242e-03 | -5.73 | GO_ENDOCYTOSIS | MSigDB lists | GO_ENDOCYTOSIS | 443 | 52 | 15632 | 1249 |
Lyn,Adrb2,Rab20,Ptk2,Ldlr,Actb,Cav1,Marco,Irf8,Rabgef1,Nr1h3,Pikfyve,Lrp8,Mapkapk2,Nck1,Olr1,Fcgr1,Trip10,Msr1,Cyfip1,Itgav,Syk,Ezr,Scarf1,Rin2,Prkce,Fcho2,Scyl2,Hp,Xkr8,Htr2b,Thbs1,Snx10,Adora2a,Sh3bp4,Snx2,Pdlim7,Jmjd6,Fgr,Calcrl,Itga4,Myo10,Hck,Cd14,Cd302,Lrp4,Src,Hsph1,Axl,Ehd1,Ly75,Dbnl |
| 3.249e-03 | -5.73 | GO_REGULATION_OF_LIPASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_LIPASE_ACTIVITY | 78 | 14 | 15632 | 1249 |
Ptafr,Nr1h3,Lpar1,Htr2a,Arf4,Rhoc,Htr2b,Ccl5,Flt1,Pdgfrb,Gna15,Prkce,Rasgrp1,Sele |
| 3.266e-03 | -5.72 | GSE7460_TCONV_VS_TREG_THYMUS_UP | MSigDB lists | GSE7460_TCONV_VS_TREG_THYMUS_UP | 194 | 27 | 15632 | 1249 |
Usp12,Trim56,Slc39a14,Inpp5b,Zfp36,Arl5b,Dusp6,Rap2c,Acvr1b,Dyrk2,Cdyl2,Kremen1,Vcan,Acvrl1,Irgq,Gpr18,Otud1,Acpp,P4ha2,Pde3b,Ddx58,Slc30a1,Slco3a1,Nxf1,Znrf3,Tlr6,Egr1 |
| 3.274e-03 | -5.72 | GSE12366_NAIVE_VS_MEMORY_BCELL_DN | MSigDB lists | GSE12366_NAIVE_VS_MEMORY_BCELL_DN | 166 | 24 | 15632 | 1249 |
Dennd1b,Slc2a1,P2ry12,Cd80,Gclc,Atp2b4,Nek6,Fas,Traf1,Plek,Ccr1,Pik3r6,Lmo4,Ptch1,C1rl,Daam1,Samsn1,Cd82,Gfpt1,Osbpl3,Nfil3,Rnf19b,Acsl1,Ptafr |
| 3.274e-03 | -5.72 | GSE14000_4H_VS_16H_LPS_DC_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_UP | 166 | 24 | 15632 | 1249 |
Clcn5,Ncoa7,Samhd1,Zc3hav1,Dnase1l3,Ciita,Ubash3b,Ddx58,Evl,Parp14,Pla2g4a,Tnc,Ggct,Cyfip1,Homer1,Tnf,Flt1,Prkx,Oasl1,Btg2,Srxn1,Zc3h12c,Atm,Pdk3 |
| 3.274e-03 | -5.72 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP | 166 | 24 | 15632 | 1249 |
Jun,Fos,Dusp1,Arl4a,Irs2,Nlrp3,Stat2,Vcpip1,Olfml3,Zc3hav1,Aff1,Zbp1,Zbtb5,Slc7a2,Ptch1,Klf2,Cd69,Rap1gap2,Fabp7,Fpr1,Dyrk2,Tlr3,Ptger4,Plcl2 |
| 3.274e-03 | -5.72 | GO_REGULATION_OF_OSSIFICATION | MSigDB lists | GO_REGULATION_OF_OSSIFICATION | 166 | 24 | 15632 | 1249 |
Il6,Egr2,Pla2g4a,Acvr1,Lrp4,Tnf,Bmp2,Pbx1,Notch1,Bcor,Intu,Hif1a,Pdlim7,Csf1,Fzd1,Jag1,Gja1,Ccr1,Ptch1,P2ry2,Fam20c,Ptk2,Ptger4,Adrb2 |
| 3.274e-03 | -5.72 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_DN | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_DN | 166 | 24 | 15632 | 1249 |
Cd180,Rnf135,Itga4,Hhex,Nupr1,Prrg4,Angpt1,Crlf3,Ciita,Adhfe1,Abcc5,Ogfrl1,Triobp,Cebpd,Fcgr2b,Ms4a6d,Itga9,Rnaset2b,Nfxl1,Rnaset2a,Cep350,Sipa1l1,Slc7a8,Rap1gap2 |
| 3.276e-03 | -5.72 | Hexokinase_N | interpro domains | IPR022672 | 5 | 3 | 19984 | 1430 |
Hk3,Hk2,Hk1 |
| 3.276e-03 | -5.72 | Hexokinase_C | interpro domains | IPR022673 | 5 | 3 | 19984 | 1430 |
Hk1,Hk3,Hk2 |
| 3.276e-03 | -5.72 | Hexokinase | interpro domains | IPR001312 | 5 | 3 | 19984 | 1430 |
Hk1,Hk3,Hk2 |
| 3.276e-03 | -5.72 | Hexokinase_BS | interpro domains | IPR019807 | 5 | 3 | 19984 | 1430 |
Hk1,Hk2,Hk3 |
| 3.276e-03 | -5.72 | IL-1_CS | interpro domains | IPR020877 | 5 | 3 | 19984 | 1430 |
Il1a,Il1rn,Il1b |
| 3.278e-03 | -5.72 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN | 112 | 18 | 15632 | 1249 |
Tcf4,Lmo4,Klf3,Parp8,Cers6,Cnn3,Slc44a1,Clec4d,Sell,Evl,Itga5,Igf1r,Crim1,Prkar2b,Tnks1bp1,Fam102b,Clcf1,Pde3b |
| 3.283e-03 | -5.72 | scaffold protein binding | molecular function | GO:0097110 | 71 | 12 | 20217 | 1400 |
Phf6,Homer1,Mdm2,Trem1,Casp8,Src,Atp2b4,Gja1,Casp1,Lrp4,Casp4,Map2k1 |
| 3.283e-03 | -5.72 | GO_RIBONUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_RIBONUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | 62 | 12 | 15632 | 1249 |
Ak4,Tpi1,Ldha,Pfkl,Hk3,Pgk1,Pfkfb3,Eno1,Eno2,Hk1,Hk2,Ampd3 |
| 3.283e-03 | -5.72 | PID_ENDOTHELIN_PATHWAY | MSigDB lists | PID_ENDOTHELIN_PATHWAY | 62 | 12 | 15632 | 1249 |
Jak2,Fos,Gna15,Map2k1,Jun,Src,Ednrb,Edn1,Pla2g4a,Slc9a1,Cysltr2,Prkce |
| 3.283e-03 | -5.72 | GO_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY | 62 | 12 | 15632 | 1249 |
Prkce,Sele,Rasgrp1,Flt1,Ccl5,Gna15,Pdgfrb,Arf4,Htr2a,Htr2b,Lpar1,Ptafr |
| 3.283e-03 | -5.72 | GO_RESPONSE_TO_OSMOTIC_STRESS | MSigDB lists | GO_RESPONSE_TO_OSMOTIC_STRESS | 62 | 12 | 15632 | 1249 |
Slc2a1,Rcsd1,Hif1a,Kmo,Ccl5,Plk3,Tlr3,Tnf,Relb,Errfi1,Tspo,Icosl |
| 3.283e-03 | -5.72 | WILCOX_RESPONSE_TO_PROGESTERONE_DN | MSigDB lists | WILCOX_RESPONSE_TO_PROGESTERONE_DN | 62 | 12 | 15632 | 1249 |
Clic4,Tnfsf10,Thbs1,Plau,Igf1r,Atp2b4,Frmd4a,Piezo1,Pdlim7,Inhba,Tra2a,Ccnd1 |
| 3.284e-03 | -5.72 | mouse chr13 | chromosome location | mouse chr13 | 279 | 29 | 24173 | 1464 |
Syk,Nfil3,Serpinb6b,Ap3b1,Dek,Serpinb9b,Tent4a,Caml,Ctla2a,BC147527,Serpinb9,Cd83,Ctla2b,Tgfbi,Jarid2,Glrx,Trip13,Parp8,Zfp456,Hmgcs1,Ptch1,Rgs14,Inhba,Vcan,Gcnt2,Gng4,Cdyl,Ddx4,Edn1 |
| 3.293e-03 | -5.72 | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP | MSigDB lists | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP | 301 | 38 | 15632 | 1249 |
Nr3c1,Tnfsf8,Slc44a1,Ppp2r5a,Triobp,Lipe,Insl6,Rnf114,Ppp6r1,B4galt4,Rbbp8,Bcl6,Zmynd15,Sgk3,Aim2,Usp25,Atp11a,Kmo,Stat2,Gbe1,Aldh1b1,Papss2,Nmi,Ube2e2,Hk2,Gdf15,Daam1,Plekha2,Golga3,Dcbld2,Gfi1,Sp110,Tcea1,Atp10a,St3gal1,Mmp9,Ms4a6d,Ier3 |
| 3.294e-03 | -5.72 | GO_REGULATION_OF_MITOTIC_CELL_CYCLE | MSigDB lists | GO_REGULATION_OF_MITOTIC_CELL_CYCLE | 433 | 51 | 15632 | 1249 |
Nek6,Pttg1,Plagl1,Phip,Tpx2,Pim3,Chmp4b,Tnks1bp1,Cenpe,Psmd10,Edn1,Pdpn,Cnot4,Tmod3,Pim2,Cdkn1a,Atm,Psmb8,Pid1,Ptch1,Cenpj,Psme2,Ube2e2,Sirt1,Casp2,Psme1,Ube2e1,Plk3,Pml,Il1a,Sphk1,Psmb10,Pbx1,Dusp1,Psmb9,Ankrd17,Ccnd1,Mdm2,Hspa2,Psma6,Parp3,Smc5,Psmb6,Pim1,Il1b,Plk2,Asns,Pdgfrb,Gpr132,Pdgfb,Btg2 |
| 3.300e-03 | -5.71 | phosphatase activity | molecular function | GO:0016791 | 267 | 31 | 20217 | 1400 |
Ubash3b,Pfkfb3,Dusp8,Nt5c3,Eya4,Dusp14,Dusp4,Inpp1,Acp2,Dusp6,Ppp2r2a,Dusp16,Ppm1k,Plpp3,Dusp5,Phlpp1,Inpp5b,Plpp1,Ptprj,Minpp1,Dusp28,Acp5,Dusp2,Mtmr14,Phlpp2,Ppp2r5a,Ppm1l,Dusp1,Ppp2r1b,Ptpn2,Acpp |
| 3.332e-03 | -5.70 | regulation of steroid metabolic process | biological process | GO:0019218 | 101 | 15 | 20694 | 1406 |
Il1a,Tnf,Egr1,Nfkb1,Stat5a,Tspo,Igf1r,Ldlr,Bmp2,Il1b,Gfi1,Adora2b,Sirt1,Nr3c1,Ttc39b |
| 3.335e-03 | -5.70 | positive regulation of response to tumor cell | biological process | GO:0002836 | 16 | 5 | 20694 | 1406 |
Klrk1,Pvr,Nectin2,Cd274,Il12b |
| 3.335e-03 | -5.70 | positive regulation of immune response to tumor cell | biological process | GO:0002839 | 16 | 5 | 20694 | 1406 |
Klrk1,Pvr,Cd274,Nectin2,Il12b |
| 3.335e-03 | -5.70 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | biological process | GO:0002504 | 16 | 5 | 20694 | 1406 |
Cd74,H2-Aa,H2-Ab1,H2-Eb1,Fcgr2b |
| 3.335e-03 | -5.70 | negative regulation of leukocyte chemotaxis | biological process | GO:0002689 | 16 | 5 | 20694 | 1406 |
Slamf8,Dusp1,Gpr18,Ccl12,Stap1 |
| 3.335e-03 | -5.70 | antigen processing and presentation of peptide antigen via MHC class II | biological process | GO:0002495 | 16 | 5 | 20694 | 1406 |
Cd74,H2-Aa,H2-Ab1,Fcgr2b,H2-Eb1 |
| 3.335e-03 | -5.70 | regulation of monocyte differentiation | biological process | GO:0045655 | 16 | 5 | 20694 | 1406 |
Gpr68,Myc,Jun,Cd74,Csf1 |
| 3.335e-03 | -5.70 | copper ion homeostasis | biological process | GO:0055070 | 16 | 5 | 20694 | 1406 |
Cutc,Sco1,Prnp,Slc31a2,Slc31a1 |
| 3.335e-03 | -5.70 | negative regulation of viral release from host cell | biological process | GO:1902187 | 16 | 5 | 20694 | 1406 |
Trim56,Pml,Trim26,Trim13,Trim21 |
| 3.341e-03 | -5.70 | Hexokinase_2 | pfam domains | PF03727 | 5 | 3 | 18711 | 1348 |
Hk1,Hk3,Hk2 |
| 3.341e-03 | -5.70 | Hexokinase_1 | pfam domains | PF00349 | 5 | 3 | 18711 | 1348 |
Hk1,Hk3,Hk2 |
| 3.350e-03 | -5.70 | endoplasmic reticulum membrane | cellular component | GO:0005789 | 508 | 51 | 20747 | 1409 |
Rhbdf2,Gm5431,Slc37a3,Pml,Gm4951,Pnpt1,Vrk2,Rab19,F830016B08Rik,H2-Q7,Tmem178,Gm12185,Zc3h12a,Gm4841,Tap1,9930111J21Rik1,Iigp1,H2-Q4,Tmem67,Ifi47,Tgtp1,Tap2,Ext1,H2-Q6,Sgms2,Dhrs9,Traf2,Tmtc2,Rtn1,Igtp,Dst,Pigv,Mtdh,Ch25h,Rnf139,Irgm2,Cept1,Rab10,Plpp3,Trim13,Itpr1,Pgap2,Tgtp2,Rrbp1,Gramd1a,Rsad2,Irgm1,Lnpk,Tapbp,Dnajb2,Ero1l |
| 3.354e-03 | -5.70 | chaperone cofactor-dependent protein refolding | biological process | GO:0051085 | 30 | 7 | 20694 | 1406 |
Hspa2,Hsph1,Ero1l,Hspa1b,Hspa1a,Dnajb4,Cd74 |
| 3.354e-03 | -5.70 | inflammatory response to antigenic stimulus | biological process | GO:0002437 | 30 | 7 | 20694 | 1406 |
Serpinb9,Tnf,Rasgrp1,Notch1,Icam1,Notch2,Fcgr1 |
| 3.354e-03 | -5.70 | positive regulation of phosphatase activity | biological process | GO:0010922 | 30 | 7 | 20694 | 1406 |
Ripk3,Ppp1r15b,Bmp2,Plek,Pdgfrb,Jak2,Ppp1r15a |
| 3.354e-03 | -5.70 | regulation of phospholipase C activity | biological process | GO:1900274 | 30 | 7 | 20694 | 1406 |
Ptafr,Pdgfrb,Htr2b,Flt1,Htr2a,Sele,Lpar1 |
| 3.354e-03 | -5.70 | regulation of homotypic cell-cell adhesion | biological process | GO:0034110 | 30 | 7 | 20694 | 1406 |
Lyn,Ccl5,Pdpn,Map2k1,Syk,Adrb2,Ubash3b |
| 3.354e-03 | -5.70 | positive regulation of macrophage activation | biological process | GO:0043032 | 30 | 7 | 20694 | 1406 |
Stap1,Tlr6,Thbs1,Ctsc,Lgals9,Il4ra,Il10 |
| 3.354e-03 | -5.70 | regulation of tumor necrosis factor-mediated signaling pathway | biological process | GO:0010803 | 30 | 7 | 20694 | 1406 |
Rffl,Casp1,Traf2,Ptpn2,Casp4,Sphk1,Syk |
| 3.355e-03 | -5.70 | Zfp467 (zinc finger protein 467) | protein interactions | 68910 | 4 | 3 | 7778 | 753 |
Stat3,Stat1,Stat4 |
| 3.355e-03 | -5.70 | Mtf1 (metal response element binding transcription factor 1) | protein interactions | 17764 | 4 | 3 | 7778 | 753 |
Rnf14,Nr4a3,Hif1a |
| 3.355e-03 | -5.70 | TNFRSF19 (TNF receptor superfamily member 19) | protein interactions | 55504 | 4 | 3 | 7778 | 753 |
Traf5,Traf1,Traf2 |
| 3.355e-03 | -5.70 | Prlr (prolactin receptor) | protein interactions | 19116 | 4 | 3 | 7778 | 753 |
Jak2,Stat5a,Nectin4 |
| 3.355e-03 | -5.70 | EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma) | protein interactions | 1968 | 4 | 3 | 7778 | 753 |
Hsph1,Rrbp1,Ksr1 |
| 3.359e-03 | -5.70 | epithelial cell morphogenesis | biological process | GO:0003382 | 46 | 9 | 20694 | 1406 |
Frmd6,Col18a1,Flnb,Plod3,Clic4,Palld,Met,Spint2,Rilpl1 |
| 3.359e-03 | -5.70 | plasma membrane invagination | biological process | GO:0099024 | 46 | 9 | 20694 | 1406 |
Fcgr2b,Spire1,Xkr8,Rac3,Treml4,Thbs1,Fcgr1,Marco,Msr1 |
| 3.366e-03 | -5.69 | GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_DN | MSigDB lists | GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_DN | 185 | 26 | 15632 | 1249 |
Ednrb,Ahrr,Map2k1,Stxbp3,Usp12,Etnk1,Map3k8,Il2rg,Cox18,Rnf145,Rcn1,Tmem123,Dr1,Vcam1,Cflar,Hivep2,Serp1,Arhgef3,Rhoq,Fgl2,Palld,Nfkbiz,Papss2,Slc28a2,Hck,Cd164 |
| 3.366e-03 | -5.69 | GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP | 185 | 26 | 15632 | 1249 |
Dusp16,Lacc1,Gca,Irak2,Slfn9,Notch2,Acsl1,Gpd2,Tlr3,Ptprj,Tdrd7,Trim14,Plekha2,Ppm1k,St3gal6,Stxbp1,Irf2,Marcksl1,Nr3c1,Slfn8,Tbc1d1,Irgm2,Tpst1,Itpr1,Cyfip1,Slc25a37 |
| 3.366e-03 | -5.69 | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN | 185 | 26 | 15632 | 1249 |
Gem,Il10,Asns,Eef1e1,Flnb,Phlda1,Pstpip2,Rab20,Adrb2,Arid5b,Phyh,Stat1,Ell2,Nfil3,Igf1r,Bambi,Cd82,Sh3bgrl2,Itgav,P4ha2,Dusp1,Src,Gadd45g,Mxd1,Lipg,Traf5 |
| 3.366e-03 | -5.69 | GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | MSigDB lists | GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | 185 | 26 | 15632 | 1249 |
Rab3ip,Ifit1,Ddx60,Atp11a,Irs2,Ifi44,Hdac1,Dhx58,Spsb1,Swap70,Ets2,Pkp4,Pmepa1,Smox,Oasl1,Rnf145,Cacnb3,Nr4a3,Bcl9,Nrp2,Wdr59,Eif4g2,Ccnj,Eno2,Map4k4,Irf7 |
| 3.366e-03 | -5.69 | GSE20727_DNFB_ALLERGEN_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN | MSigDB lists | GSE20727_DNFB_ALLERGEN_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN | 185 | 26 | 15632 | 1249 |
Fgl2,Cpd,Carhsp1,Nat2,Tspan3,Trmt1l,Apobec3,Slc16a3,Dnase1l3,Hif1a,Nmral1,Prnp,Abr,Mcm10,Fas,Pml,Tpi1,Fam72a,Xaf1,Srxn1,Isg20,Trip13,Flnb,Lacc1,Mafg,Dgkh |
| 3.374e-03 | -5.69 | INTERFERONAB | prints domains | PR00266 | 24 | 6 | 5821 | 374 |
Ifna4,Ifna2,Ifna6,Ifna5,Ifnb1,Ifna1 |
| 3.387e-03 | -5.69 | regulation of cellular carbohydrate metabolic process | biological process | GO:0010675 | 152 | 20 | 20694 | 1406 |
Pdk3,Ddit4,Ranbp2,Ptpn2,Ier3,Sirt1,Src,Dyrk2,Plek,Stat3,Nr3c1,Nupr1,Prkce,Rubcnl,Kat2b,Irs2,Gfpt1,Ptafr,Hif1a,Il6 |
| 3.418e-03 | -5.68 | IL-9 Signaling Pathway | WikiPathways | WP10 | 24 | 8 | 4813 | 540 |
Stat3,Stat1,Irs2,Stat5a,Map2k1,Il2rg,Tyk2,Socs3 |
| 3.452e-03 | -5.67 | GO_PURINE_CONTAINING_COMPOUND_CATABOLIC_PROCESS | MSigDB lists | GO_PURINE_CONTAINING_COMPOUND_CATABOLIC_PROCESS | 47 | 10 | 15632 | 1249 |
Gda,Enpp4,Pde5a,Pde7b,Samhd1,Pde3b,Pnp2,Pde1b,Ampd3,Pde4b |
| 3.452e-03 | -5.67 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 47 | 10 | 15632 | 1249 |
Adrb2,Trim13,Hif1a,Sqstm1,Ripk2,Larp1,Sirt1,Kdr,Bnip3,Nod1 |
| 3.459e-03 | -5.67 | GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | 342 | 42 | 15632 | 1249 |
Bcl2l11,Src,Tnf,Eif2ak2,Crbn,Birc2,Jun,Cyfip1,Prkce,Triobp,Tlr6,Stxbp1,Fas,Aim2,Nck1,Evl,Mpp7,Icam1,Cdc42ep2,Kif9,Hck,Chmp4b,Myadm,Plek,Lmo4,Cav1,Irf8,Piezo1,Xaf1,Vasp,Csf3,Rictor,Tmod3,Ptger4,Mefv,Cdc42ep4,Spire1,Hcls1,Fscn1,Whamm,Pmepa1,Sec24b |
| 3.459e-03 | -5.67 | GO_PROTEIN_DEPHOSPHORYLATION | MSigDB lists | GO_PROTEIN_DEPHOSPHORYLATION | 176 | 25 | 15632 | 1249 |
Ppm1k,Ppp1r15a,Dusp6,Ppp1r15b,Ppp2r3a,Eya4,Phlpp2,Dusp5,Mtmr14,Ptprj,Ppp2r2a,Dusp28,Acp2,Dusp16,Ptpn2,Dusp1,Dusp4,Phlpp1,Dusp2,Dusp8,Cycs,Ppm1l,Ubash3b,Nck1,Dusp14 |
| 3.459e-03 | -5.67 | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 176 | 25 | 15632 | 1249 |
H3f3b,Dram1,Azi2,Osgin2,Pstpip2,Csf1,Bst1,C1rl,Hdc,Pdgfc,Hhex,Mxd1,Psme1,P2ry14,Prnp,Plagl1,Peli1,Ppp2r5a,Slc44a1,Rhoq,Kdm5b,Txnrd1,Sqstm1,Dpy19l1,Swap70 |
| 3.459e-03 | -5.67 | TGTGTGA_MIR377 | MSigDB lists | TGTGTGA_MIR377 | 176 | 25 | 15632 | 1249 |
D16Ertd472e,Fut8,Egr2,Rbpms,Mdm2,Triobp,Egr1,Fam133b,Vcpip1,Ednrb,Atxn7l1,Rictor,Eya4,Jag1,Max,Cpeb4,Hmox1,Phf6,Rnf145,Osgin2,Gpr85,Rpgrip1l,Rsbn1,Agpat4,Armc8 |
| 3.459e-03 | -5.67 | GSE21546_WT_VS_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_WT_VS_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | 176 | 25 | 15632 | 1249 |
Dusp16,Pim1,Azi2,Tlr9,Nfkbid,Srxn1,Arl5b,Gem,Fosb,Jarid2,Junb,Kif9,Ube2f,Marcksl1,Csrnp1,Egr1,Hspa2,Dtnb,Dusp8,Dusp2,Cish,Bcl6,Nr4a1,Gadd45b,Hsph1 |
| 3.459e-03 | -5.67 | GSE15767_MED_VS_SCS_MAC_LN_DN | MSigDB lists | GSE15767_MED_VS_SCS_MAC_LN_DN | 176 | 25 | 15632 | 1249 |
Slc37a3,Wdr43,Dnajb2,Tnfsf10,Cd82,Tax1bp1,Mppe1,Smox,Pim2,Jag1,Ptch1,Sipa1l1,4930523C07Rik,Rab19,Traf1,Mllt6,Atp13a1,Gpr68,Phgdh,Mdn1,Setdb2,Hivep2,Gramd1a,Spn,Psip1 |
| 3.459e-03 | -5.67 | CYCLIN_D1_KE_.V1_UP | MSigDB lists | CYCLIN_D1_KE_.V1_UP | 176 | 25 | 15632 | 1249 |
Ahr,Rgs3,Hk3,Batf,Traf1,Col18a1,Plk3,Cebpd,Dusp4,Cox17,Casp3,Zyx,Birc2,Hspa1a,Ets2,Hsph1,Cdkn1a,Pfkl,Dusp5,Egr3,Bcl9,Dmwd,Lcn2,Asns,Fzd5 |
| 3.463e-03 | -5.67 | p53-like_TF_DNA-bd | interpro domains | IPR008967 | 44 | 9 | 19984 | 1430 |
Stat3,Stat1,Stat2,Nfkb1,Nfkb2,Rel,Stat5a,Relb,Stat4 |
| 3.476e-03 | -5.66 | SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN | MSigDB lists | SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN | 26 | 7 | 15632 | 1249 |
Triobp,Relb,Traf1,Atp2b4,Nfkb2,Slc7a5,Atf3 |
| 3.476e-03 | -5.66 | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_UP | MSigDB lists | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_UP | 26 | 7 | 15632 | 1249 |
Nqo1,Ptges,Tspo,Cp,Cd34,Trib3,Atf3 |
| 3.476e-03 | -5.66 | NAKAJIMA_EOSINOPHIL | MSigDB lists | NAKAJIMA_EOSINOPHIL | 26 | 7 | 15632 | 1249 |
P2ry14,Marcksl1,Plaur,Olr1,Ccr3,Ccl4,Rgs1 |
| 3.476e-03 | -5.66 | GENTILE_UV_RESPONSE_CLUSTER_D9 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D9 | 26 | 7 | 15632 | 1249 |
Met,Idi1,Cited2,Rrs1,Swap70,Acvr1b,Dyrk2 |
| 3.476e-03 | -5.66 | GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | 26 | 7 | 15632 | 1249 |
C3,Nox1,Ptgs2,Adora2b,Hif1a,Il1a,Il1b |
| 3.476e-03 | -5.66 | GO_PURINERGIC_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_PURINERGIC_RECEPTOR_SIGNALING_PATHWAY | 26 | 7 | 15632 | 1249 |
Ptafr,P2ry13,P2ry14,P2ry2,Adora2b,P2ry12,Adora2a |
| 3.476e-03 | -5.66 | GO_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION | 26 | 7 | 15632 | 1249 |
Msr1,Nr1h3,Nfkbia,Itgav,Nfkb1,Pf4,Csf1 |
| 3.476e-03 | -5.66 | GO_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 26 | 7 | 15632 | 1249 |
Atm,Cd74,Psmd10,Mdm2,Sirt1,Spred1,Eef1e1 |
| 3.477e-03 | -5.66 | regulation of organelle assembly | biological process | GO:1902115 | 206 | 25 | 20694 | 1406 |
Palld,Fscn1,Chmp4b,Gpsm2,Dync1h1,Tmem67,Edn1,Sipa1l1,Nupr1,Sdc1,Kat2b,Hck,Hspa1b,Src,Kif9,Plk2,Sdc4,Ezr,Pikfyve,Hap1,Cenpj,Hspa1a,G3bp2,Tnf,Syne2 |
| 3.478e-03 | -5.66 | apoptotic cell clearance | biological process | GO:0043277 | 38 | 8 | 20694 | 1406 |
Axl,Jmjd6,Nr1h3,Xkr8,Rac3,Thbs1,Marco,Itgav |
| 3.505e-03 | -5.65 | Znf_RING_CS | interpro domains | IPR017907 | 155 | 21 | 19984 | 1430 |
Trim36,Trim30a,Pml,Trim21,Cop1,Traf2,Traf5,Trim12a,Trim56,Rnf135,Trim34a,Trim13,Bfar,Rnf14,Dtx3l,Rnf114,Rnf31,Trim12c,Mid1,Trim30d,Pcgf5 |
| 3.507e-03 | -5.65 | LEE_INTRATHYMIC_T_PROGENITOR | MSigDB lists | LEE_INTRATHYMIC_T_PROGENITOR | 14 | 5 | 15632 | 1249 |
Hivep3,Rims3,Ets2,Rras2,Tnfsf4 |
| 3.507e-03 | -5.65 | INGA_TP53_TARGETS | MSigDB lists | INGA_TP53_TARGETS | 14 | 5 | 15632 | 1249 |
Thbs1,Ier3,Cdkn1a,Mdm2,Fos |
| 3.507e-03 | -5.65 | GO_POSITIVE_REGULATION_OF_METANEPHROS_DEVELOPMENT | MSigDB lists | GO_POSITIVE_REGULATION_OF_METANEPHROS_DEVELOPMENT | 14 | 5 | 15632 | 1249 |
Pdgfrb,Myc,Egr1,Lif,Pdgfb |
| 3.507e-03 | -5.65 | GO_NEGATIVE_REGULATION_OF_MYOTUBE_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MYOTUBE_DIFFERENTIATION | 14 | 5 | 15632 | 1249 |
Cflar,Notch1,Daxx,Hdac1,Cxcl10 |
| 3.507e-03 | -5.65 | GO_NEGATIVE_REGULATION_OF_B_CELL_PROLIFERATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_B_CELL_PROLIFERATION | 14 | 5 | 15632 | 1249 |
Prdm1,Atm,Casp3,Il10,Lyn |
| 3.507e-03 | -5.65 | VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP | MSigDB lists | VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP | 14 | 5 | 15632 | 1249 |
Pfkfb3,Bnip3,Hk2,Maff,Ccnd2 |
| 3.507e-03 | -5.65 | BIOCARTA_RANKL_PATHWAY | MSigDB lists | BIOCARTA_RANKL_PATHWAY | 14 | 5 | 15632 | 1249 |
Eif2ak2,Ifnar1,Nfkb1,Fos,Ifnb1 |
| 3.507e-03 | -5.65 | GO_REGULATION_OF_PODOSOME_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_PODOSOME_ASSEMBLY | 14 | 5 | 15632 | 1249 |
Hck,Src,Fscn1,Tnf,Kif9 |
| 3.507e-03 | -5.65 | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN | MSigDB lists | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN | 14 | 5 | 15632 | 1249 |
Plk2,Atp2b4,Tcf4,Olfml3,Glrx |
| 3.507e-03 | -5.65 | FERRANDO_LYL1_NEIGHBORS | MSigDB lists | FERRANDO_LYL1_NEIGHBORS | 14 | 5 | 15632 | 1249 |
Hhex,Cd34,Sod2,Ccnd2,Sell |
| 3.507e-03 | -5.65 | CAIRO_PML_TARGETS_BOUND_BY_MYC_DN | MSigDB lists | CAIRO_PML_TARGETS_BOUND_BY_MYC_DN | 14 | 5 | 15632 | 1249 |
Cav1,Ccnd1,Pdgfrb,Cdkn1a,Hspa1a |
| 3.507e-03 | -5.65 | ZHAN_LATE_DIFFERENTIATION_GENES_DN | MSigDB lists | ZHAN_LATE_DIFFERENTIATION_GENES_DN | 14 | 5 | 15632 | 1249 |
Tcea1,Bcl6,Marcksl1,Syk,Rhoh |
| 3.510e-03 | -5.65 | YAMAZAKI_TCEB3_TARGETS_DN | MSigDB lists | YAMAZAKI_TCEB3_TARGETS_DN | 195 | 27 | 15632 | 1249 |
Hmga1,Slc2a1,Psip1,Sod2,Gclm,Mdn1,Arl4a,Agtrap,Col18a1,Spred1,Ahsa1,Fzd5,Klf2,Ptch1,Jarid2,Ccne1,Dusp6,Hat1,Spint2,Sap30,Phyh,Pim1,Ttc39b,Hmgcs1,Uchl1,Igf1r,Tcea1 |
| 3.512e-03 | -5.65 | GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_DN | MSigDB lists | GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_DN | 104 | 17 | 15632 | 1249 |
Cd83,Ccl4,Hsd17b7,Dnajb2,Marcksl1,Sema4c,Upp1,Adora2b,Slpi,Egr2,Tmem26,Gpr68,Rhou,Fam43a,Swap70,Cnp,Casp4 |
| 3.523e-03 | -5.65 | GO_INTRACELLULAR_VESICLE | MSigDB lists | GO_INTRACELLULAR_VESICLE | 1173 | 119 | 15632 | 1249 |
Plekhf2,Hsph1,Slc2a1,Timp1,Itpr1,Acpp,Rhoq,Dbnl,Rab9,Dennd1b,Mdm2,Apba1,Slc30a4,H2-Q7,Sphk1,Agtrap,Socs1,Hck,Notch1,Gch1,Slc4a7,Cnp,Phlda1,Tlr1,Inpp5b,Pdgfb,Stx11,Hap1,Scyl2,Fndc3a,Cd55,H2-Ab1,Chic2,Clic4,Thbs1,Sec24b,Pf4,Abcc4,Vegfc,Il15ra,Ccl12,H2-Q4,Rab32,Msr1,Irgm2,Edn1,Tlr6,Dmxl2,Arrdc4,Fcgr1,Htr2a,Prdx1,Herc3,Lnpep,Ptch1,Marco,Mefv,Tlr2,Kdr,Tmem67,Ap3m2,Esd,H2-Q6,Rab11fip1,Slc39a4,Rab21,Prdx5,Cd74,F11r,Sgk3,Gja1,H2-Eb1,Pde4b,Vps54,Serpine1,Pdgfrb,Fzd5,H2-Aa,Stxbp3,Rab10,Sh3bp4,Rapgef2,Hp,Spire1,Fcho2,Plat,Sec24a,Pcdh7,Acp2,Il1b,Itgav,Sqstm1,Syk,Trim36,Aftph,Mmp14,Ctsc,Pla2g4a,Scarf1,Optn,Ap3b1,Stxbp1,Fas,Pikfyve,Atm,Cav1,Vezt,Trim21,Stx6,Itga5,Tlr9,Sema4c,Rab20,Lpar1,Ldlr,Znrf1,Clcn7,Whamm,Dusp16 |
| 3.524e-03 | -5.65 | neuron development | biological process | GO:0048666 | 845 | 78 | 20694 | 1406 |
Rapgef2,Map4k4,Lhx2,Nrp2,Sema3c,Dock10,Map2k1,Hap1,Micall2,Sema4a,Lst1,Cyfip1,Il6,Scn1b,Dst,Pdgfb,Lif,Phgdh,Mturn,Vasp,Lrp4,Palld,Btg2,Arf4,Scarf1,Notch1,Flrt3,Casp3,Jak2,Ptch1,Gja1,Dbnl,Crkl,Spire1,Cdk5r1,Nr4a3,Lyn,Klf7,Prdm1,Evl,Sdc2,Fcgr2b,Sdc4,Cnp,Kdr,Egr2,Stxbp1,Kif5c,Tnc,Mecp2,Adora2a,Jun,Sod2,Ehd1,Slc4a7,Actb,Sec24b,Itga4,Rac3,Clic5,Agrn,Rnd1,Mark2,Ptk2,C3,Triobp,Ntng2,Tsku,Ext1,Tmem67,Psd,Igf1r,Lrp8,Rab10,Fas,Uchl1,Igsf9,Flrt2 |
| 3.528e-03 | -5.65 | GO_FILOPODIUM | MSigDB lists | GO_FILOPODIUM | 87 | 15 | 15632 | 1249 |
Osbpl3,Fscn1,Vcam1,Myo10,Spata13,Pdpn,Antxr1,Vasp,Syne2,Itgav,Dync1h1,Ezr,Cd302,Acpp,Myo1b |
| 3.528e-03 | -5.65 | GO_RESPONSE_TO_FATTY_ACID | MSigDB lists | GO_RESPONSE_TO_FATTY_ACID | 87 | 15 | 15632 | 1249 |
Pid1,Src,Pdk3,Ass1,Tnc,Edn1,Prkce,Ptgs2,Ptafr,Acsl1,Fabp3,Tnfsf4,Ptger4,Zc3h12a,Il1b |
| 3.528e-03 | -5.65 | BROWNE_HCMV_INFECTION_20HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_20HR_DN | 87 | 15 | 15632 | 1249 |
Nqo1,Akt3,Acpp,Sipa1l1,Axl,Pde4b,Tnfrsf14,Ahr,Glrx,Rras2,Rnd3,Serpinb2,Gbe1,Traf3ip2,Filip1l |
| 3.542e-03 | -5.64 | GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | MSigDB lists | GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | 167 | 24 | 15632 | 1249 |
Clic4,Socs3,Met,Timeless,Csf1,Ptch1,Fzd5,Il10,Sema3c,Notch1,Pbx1,Bmp2,Pml,Prdm1,Hhex,Kdm5b,Acvr1,Il6,Myc,Mmp14,Edn1,Tnc,Spry2,Src |
| 3.542e-03 | -5.64 | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP | 167 | 24 | 15632 | 1249 |
Fos,Tpst1,Gadd45b,Bbx,Rab9,Tnfsf8,Nxf1,Ier2,Rnf139,Samhd1,Tnfaip3,Golga3,Atm,Sirt1,Spen,Flnb,Zfp36,Fam53c,Xkr8,Ptger4,Itga5,Zc3h12a,Ppfibp2,Plcl2 |
| 3.563e-03 | -5.64 | response to antineoplastic agent | biological process | GO:0097327 | 73 | 12 | 20694 | 1406 |
Hmox1,Daxx,Egr1,Ifnb1,Jak2,Pdgfb,Larp1,Slc31a1,Ddit4,Zc3h12a,Nr3c1,Timeless |
| 3.563e-03 | -5.64 | positive regulation of striated muscle cell differentiation | biological process | GO:0051155 | 73 | 12 | 20694 | 1406 |
Il4ra,Ehd1,Hopx,Tnfsf14,Cxcl9,Edn1,Trip10,Mmp14,Ccl8,Nr3c1,Gdf15,Sirt1 |
| 3.576e-03 | -5.63 | negative regulation of G protein-coupled receptor signaling pathway | biological process | GO:0045744 | 55 | 10 | 20694 | 1406 |
Ccl5,Rgs14,Htr2b,Met,Plek,Pde4b,Rpgrip1l,Atp2b4,Grk3,Adrb2 |
| 3.576e-03 | -5.63 | endocytic vesicle | cellular component | GO:0030139 | 174 | 22 | 20747 | 1409 |
Rapgef2,Ehd1,Zyx,Fcho2,Cdc42ep4,Tlr1,Syk,Rab9,Cdc42ep2,Stx6,Flnb,Stx11,Stxbp1,Tlr9,Stxbp3,Sphk1,Ccl2,Irgm1,Evl,Rab20,Lpar1,Rab32 |
| 3.584e-03 | -5.63 | phospholipase C-activating G protein-coupled receptor signaling pathway | biological process | GO:0007200 | 92 | 14 | 20694 | 1406 |
Fpr2,Cx3cr1,Fpr1,Gpr35,Ednrb,Htr2a,Gna15,P2ry2,Gpr18,Lpar1,P2ry12,Edn1,Htr2b,Cmklr1 |
| 3.592e-03 | -5.63 | cell cortex | cellular component | GO:0005938 | 308 | 34 | 20747 | 1409 |
Rims3,Rhoq,Eno2,Rhof,Actb,Slc2a1,Rnd1,Spire1,Eno1,Cav1,Myadm,Daxx,Rhoh,Traf2,Phldb1,Nos2,Rhou,Triobp,Map2k1,Ppfia3,Mark2,Gpsm2,Agtrap,Tnfaip2,Dync1h1,Rhoc,Gypc,Dbnl,Tpm4,Rnd3,Sele,Cd302,Hcls1,Marcks |
| 3.599e-03 | -5.63 | negative regulation of CD4-positive, alpha-beta T cell differentiation | biological process | GO:0043371 | 23 | 6 | 20694 | 1406 |
Hlx,Il4ra,Tnfsf4,Bcl6,Zc3h12a,Irf1 |
| 3.599e-03 | -5.63 | positive regulation of cellular extravasation | biological process | GO:0002693 | 23 | 6 | 20694 | 1406 |
Il1a,Icam1,Itga4,Ptger4,Ptafr,Ccl2 |
| 3.599e-03 | -5.63 | proteasomal ubiquitin-independent protein catabolic process | biological process | GO:0010499 | 23 | 6 | 20694 | 1406 |
Psmb10,Keap1,Psma6,Psmb9,Psmb6,Psmb8 |
| 3.599e-03 | -5.63 | negative regulation of regulated secretory pathway | biological process | GO:1903306 | 23 | 6 | 20694 | 1406 |
Abr,Lgals9,Notch1,Hmox1,Rabgef1,Stxbp3 |
| 3.608e-03 | -5.62 | GO_TRANSITION_METAL_ION_BINDING | MSigDB lists | GO_TRANSITION_METAL_ION_BINDING | 1230 | 124 | 15632 | 1249 |
Mmp9,Dtx2,Rnf145,Mppe1,Mmp25,Znrf1,Idi1,Adam19,Lhx2,S100a8,Rnf14,Sco1,Plod2,Lap3,Lmo4,Nos2,Trim21,Trim14,Zeb1,Trim56,Xaf1,Egln3,Dcp2,Mul1,Nr1h3,Znrf3,Pikfyve,Gpc1,Phf11a,Klf7,Me1,Morc3,Nr4a1,Trim36,Sqstm1,Sod2,Rnf114,Mmp14,Mllt6,Cnot4,Dtnb,Cpd,Mid1,Pcgf5,Phf6,Nr4a3,Sec24a,Sp110,Csrp1,Trim26,Wdfy1,Pdlim7,Car13,Mmp13,Ch25h,Rnf139,Tab2,Ifih1,Rnf135,Traf5,Rnf34,Cutc,Gda,Tnfaip3,P4ha2,Phf11b,Zswim4,Plod3,Traf2,Micall2,Rnf24,Cp,Dhx58,Dyrk2,Phf11d,Mefv,Zcchc2,Fam20c,Ankib1,Birc3,Rabgef1,Rnf31,P4ha1,Lnpep,Ubr4,Lcn2,Rnf19a,Oas1a,Rasgrp1,Trim13,Prnp,Samhd1,Phf11c,Tet2,Znfx1,Zyx,Cox17,Rnf19b,Oas1g,Pim1,Lox,Nfxl1,Sec24b,Tcea1,Gch1,Oas2,Pml,Il1a,Ddx58,Kdm4a,Dtx3l,Jmjd6,Trim12c,Traf1,Bfar,Apobec3,Sp140,Birc2,Nr3c1,Rffl,Top3a,Setdb2,Mdm2,Kdm5b |
| 3.611e-03 | -5.62 | GO_AMINOGLYCAN_METABOLIC_PROCESS | MSigDB lists | GO_AMINOGLYCAN_METABOLIC_PROCESS | 158 | 23 | 15632 | 1249 |
Il1b,Ust,Gcnt2,Pim1,St3gal1,Ext1,Slc9a1,Pdgfrb,Angpt1,Gpc1,Sdc4,Il15,Extl2,St3gal6,Sdc1,St3gal3,Vcan,Chst11,Sdc2,Dse,B4galt4,Abcc5,Agrn |
| 3.616e-03 | -5.62 | GSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_DN | MSigDB lists | GSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_DN | 113 | 18 | 15632 | 1249 |
Slfn5,Slc29a3,Ttc39b,Ptafr,Rtp4,Xrn1,Kmo,Cd180,Pgm1,Oas2,Gpr68,Mmd,Edn1,Ext1,Cd40,Oas3,Zc3h12c,Rel |
| 3.623e-03 | -5.62 | death receptor binding | molecular function | GO:0005123 | 16 | 5 | 20217 | 1400 |
Nsmaf,Cflar,Casp8,Casp3,Tnfsf15 |
| 3.624e-03 | -5.62 | GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_UP | MSigDB lists | GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_UP | 186 | 26 | 15632 | 1249 |
Gclc,Gnb4,Kif9,Rhoc,Ifit1,Nupr1,Slc44a1,Il4i1,Spryd7,Tnf,Map3k6,Nfkb2,Plat,Serpinb2,Traf3ip2,Rnf19b,Dnajb4,Plscr1,St3gal5,Nfkbib,Tmeff1,Btg2,Gja1,Plk2,Asns,Myo1b |
| 3.624e-03 | -5.62 | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_DN | 186 | 26 | 15632 | 1249 |
Slc37a3,Lacc1,Ccl4,Pim1,Mob3b,Nr4a3,Ier3,Ttc39b,Pcgf5,Smpdl3b,Procr,Slc2a6,Noc4l,Rel,Plod2,Gch1,Plagl2,Cd83,Pim3,Nmral1,Nek6,Acvr1,Trip10,P4ha2,Slc7a11,Srm |
| 3.624e-03 | -5.62 | GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | MSigDB lists | GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | 186 | 26 | 15632 | 1249 |
Chst11,Il18bp,Ift57,Pla2g4a,Micall2,Rbbp8,Cd40,Tcf4,Cenpe,Aff1,Bmp2,Pttg1,Prnp,Tpx2,Papss2,Egln3,Srxn1,Pstpip2,Procr,Ltbp2,Ccne1,Clic4,Nr4a3,Sema4c,Tlr3,Mmp9 |
| 3.624e-03 | -5.62 | GSE22886_NAIVE_BCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_DC_DN | 186 | 26 | 15632 | 1249 |
Sdc2,Dennd1b,Dse,Dock4,Ankrd17,Mgat1,Cited2,Txnrd1,Slc7a11,Rhoc,Pilra,Plau,Gclc,Abr,Rars,Tpi1,Rapgef2,Pla2g7,Samsn1,Slc7a8,Slc31a2,Rnf14,Tfec,Tgfbi,Mthfd2,Hmox1 |
| 3.624e-03 | -5.62 | GSE360_CTRL_VS_L_MAJOR_DC_UP | MSigDB lists | GSE360_CTRL_VS_L_MAJOR_DC_UP | 186 | 26 | 15632 | 1249 |
Psd,Pde1b,Spry2,Ifi209,Zyx,Ifi205,Ifi213,Tle3,Samhd1,Ifi207,Smg7,Mapkbp1,Ifi214,Fabp3,Fgr,Kmo,Ifi203,Ifi208,Ifi211,Mndal,Wdr43,Vegfc,Stip1,Ifi204,Hmox1,Ptk2 |
| 3.624e-03 | -5.62 | GSE17721_POLYIC_VS_GARDIQUIMOD_0.5H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_0.5H_BMDC_DN | 186 | 26 | 15632 | 1249 |
Plk2,Slfn4,Zc3h12c,Procr,Srxn1,Timeless,Snx2,Pou2f2,Oas2,Ppp2r3a,Dnaja2,Map2k4,Map3k8,Il1rn,Slfn3,Sp110,Tfec,Spn,Trmt1l,Hmga1,Stard5,Hspa2,Ier2,Prdx1,Rnf34,Chmp4b |
| 3.627e-03 | -5.62 | regulation of protein processing | biological process | GO:0070613 | 64 | 11 | 20694 | 1406 |
Inpp5b,Serpine1,Birc2,Cst7,Birc3,Mmp14,Thbs1,Mdm2,Ctla2a,Rnf139,Src |
| 3.627e-03 | -5.62 | negative regulation of cell cycle G1/S phase transition | biological process | GO:1902807 | 64 | 11 | 20694 | 1406 |
Cdkn1a,Pml,Casp2,Cdkn2d,Ccnd1,Plk3,Ccl12,Slfn1,Mdm2,Dcun1d3,Rbl1 |
| 3.632e-03 | -5.62 | plasma membrane region | cellular component | GO:0098590 | 1194 | 105 | 20747 | 1409 |
Slco3a1,Jak2,Rims3,Hk1,Eno2,Nod2,Marcksl1,Atp2b4,Ntng2,Eno1,Igf1r,P2ry2,Cav1,Scimp,Src,Ezr,Arf4,Lcp2,Fcho2,Slc16a3,Adora2a,Tlr9,Cldnd1,Hspa1a,Nod1,Nox1,Spn,Kctd12,Slc39a4,Ptprj,Cpeb4,Stxbp1,Flrt3,Ldlr,Kcna3,Notch1,Slc7a11,Spire1,Syne2,Abcc4,Htr2a,Itga5,Gja1,Stx11,Ddx58,Slc30a1,Sele,Pdzd11,Tmem67,Rhoc,Psd,Ehd1,Cd34,Slc2a1,Slc4a7,Nlgn2,Fas,Met,Itpr1,Pdpn,Mosmo,Antxr1,Stxbp3,Cacnb3,Ptgs2,Phlpp2,Slc9a1,Il18,Ptk2,P2ry12,Fgr,Mtdh,Itga9,Cd38,Crkl,Nrp2,Dbnl,Cacna1d,Homer1,Fscn1,Sema4c,Apba1,Rapgef2,Jag1,Lrp4,Spata13,Hmox1,Cd55,Hck,Pdgfrb,Rgs14,Psd4,Adgrl2,Phlpp1,Ptch1,Plek,Abcc1,Asah2,Pdgfb,Abcb1a,Itgav,Lrp8,Sipa1l1,Lipe,Adrb2 |
| 3.651e-03 | -5.61 | nuclear envelope | cellular component | GO:0005635 | 402 | 42 | 20747 | 1409 |
Tor1aip1,Smox,Dst,Phf11b,Dpy19l1,Sh3bgrl2,Slc30a1,Phf11a,Pml,Prnp,Tent4a,Chmp4b,Parp11,Prpf38a,Trib3,Uaca,Slc16a3,Ptges,Nr4a1,Dync1h1,Tor3a,Ankrd17,Phf11c,Ednrb,Ccnd2,Phf11d,Dusp2,Rap1gap2,Nxf1,Itpr1,Bnip3,Phlpp1,Dtx2,Ranbp2,Gch1,Dnajb2,Osbpl3,Ptger4,Syne2,Myc,Cacybp,Sirt1 |
| 3.653e-03 | -5.61 | Tyr_kinase_AS | interpro domains | IPR008266 | 97 | 15 | 19984 | 1430 |
Igf1r,Fgr,Lyn,Axl,Hck,Jak2,Ptk2,Kdr,Prag1,Src,Pdgfrb,Met,Tyk2,Flt1,Syk |
| 3.657e-03 | -5.61 | GO_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | 40 | 9 | 15632 | 1249 |
Col18a1,Il10,Icam1,Serpine1,Cd40,Kdr,Thbs1,Angpt1,Tnfaip3 |
| 3.657e-03 | -5.61 | ACAACCT_MIR453 | MSigDB lists | ACAACCT_MIR453 | 40 | 9 | 15632 | 1249 |
Arid5a,Mafg,Nr4a3,Ifit1bl2,Ifit1bl1,Vasp,Scarf1,Myc,Rap2c |
| 3.657e-03 | -5.61 | HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP | 40 | 9 | 15632 | 1249 |
Stat4,H2-Aa,Ciita,Csf1,Jak2,Sell,Cdk5r1,Ms4a6d,Rhoh |
| 3.663e-03 | -5.61 | GSE14415_ACT_VS_CTRL_NATURAL_TREG_DN | MSigDB lists | GSE14415_ACT_VS_CTRL_NATURAL_TREG_DN | 149 | 22 | 15632 | 1249 |
Evl,Cd55,Bcor,Pttg1,Ccnd2,Trim13,Il15,Bambi,Fam162a,Nfil3,Nr4a1,Parp8,Dusp1,Card6,Irf7,Zeb1,Btg2,Akt3,Mdn1,Tnfsf8,Fchsd2,Taf4b |
| 3.663e-03 | -5.61 | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_UP | MSigDB lists | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_UP | 149 | 22 | 15632 | 1249 |
Fcho2,Hmox1,Fmnl2,Lacc1,Nfil3,Thbs1,Slc29a3,Slc7a8,Psat1,Ccr1,Trim14,Tlr1,Apaf1,Ahr,Samhd1,Me1,Plau,Syk,Sdc2,Fgl2,Nqo1,Egr2 |
| 3.666e-03 | -5.61 | mouse chr4 E1|4 78.17 cM | chromosome location | mouse chr4 E1|4 78.17 cM | 2 | 2 | 24173 | 1464 |
Tnfrsf8,Tnfrsf1b |
| 3.666e-03 | -5.61 | mouse chr14 A3|14 16.09 cM | chromosome location | mouse chr14 A3|14 16.09 cM | 2 | 2 | 24173 | 1464 |
Arhgef3,Arf4 |
| 3.666e-03 | -5.61 | mouse chr5 C3.1|5 32.8 cM | chromosome location | mouse chr5 C3.1|5 32.8 cM | 2 | 2 | 24173 | 1464 |
Pgm1,Tbc1d1 |
| 3.666e-03 | -5.61 | mouse chr5 F|5 60.65 cM | chromosome location | mouse chr5 F|5 60.65 cM | 2 | 2 | 24173 | 1464 |
Oas1a,Oas1g |
| 3.666e-03 | -5.61 | mouse chr17 D|17 29.08 cM | chromosome location | mouse chr17 D|17 29.08 cM | 2 | 2 | 24173 | 1464 |
Gm16712,Ebi3 |
| 3.666e-03 | -5.61 | mouse chr11 A1|11 2.94 cM | chromosome location | mouse chr11 A1|11 2.94 cM | 2 | 2 | 24173 | 1464 |
Lif,Osm |
| 3.666e-03 | -5.61 | mouse chr19 C3|19 38.8 cM | chromosome location | mouse chr19 C3|19 38.8 cM | 2 | 2 | 24173 | 1464 |
Nfkb2,Psd |
| 3.666e-03 | -5.61 | mouse chr4 C1|4 34.06 cM | chromosome location | mouse chr4 C1|4 34.06 cM | 2 | 2 | 24173 | 1464 |
Tnc,Tnfsf8 |
| 3.666e-03 | -5.61 | mouse chr17 B1|17 18.65 cM | chromosome location | mouse chr17 B1|17 18.65 cM | 2 | 2 | 24173 | 1464 |
H2-Q5,H2-Q4 |
| 3.666e-03 | -5.61 | mouse chr7 B1|7 19.3 cM | chromosome location | mouse chr7 B1|7 19.3 cM | 2 | 2 | 24173 | 1464 |
Scn1b,Gramd1a |
| 3.666e-03 | -5.61 | mouse chr13 A3.2|13 13.79 cM | chromosome location | mouse chr13 A3.2|13 13.79 cM | 2 | 2 | 24173 | 1464 |
Serpinb9,Serpinb9b |
| 3.666e-03 | -5.61 | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | MSigDB lists | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | 79 | 14 | 15632 | 1249 |
Psme2,Zfp36,Psma6,Dcp1a,Psmb8,Hspa1a,Psmd10,Psmb9,Mapkapk2,Psmb6,Psme1,Psmb10,Xrn1,Dcp2 |
| 3.677e-03 | -5.61 | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK | 122 | 19 | 15632 | 1249 |
Hsd17b12,Lipe,Plekhf2,Mtus1,Klhl25,Tank,Cd302,Ksr1,Aftph,G3bp2,Pcx,Prnp,Kat2b,Bfar,Pim3,Mapkbp1,Slc48a1,Pfkl,Abcc4 |
| 3.679e-03 | -5.61 | GO_REGULATION_OF_INTERLEUKIN_8_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_8_PRODUCTION | 55 | 11 | 15632 | 1249 |
Il1b,Nod2,Serpine1,Hspa1a,Tlr2,Il10,Ddx58,Tlr9,Tnf,Tlr3,Ptger4 |
| 3.679e-03 | -5.61 | KEGG_GLYCOLYSIS_GLUCONEOGENESIS | MSigDB lists | KEGG_GLYCOLYSIS_GLUCONEOGENESIS | 55 | 11 | 15632 | 1249 |
Hk2,Pgk1,Pfkl,Hk3,Tpi1,Ldha,Hk1,Eno2,Aldh1b1,Eno1,Pgm1 |
| 3.679e-03 | -5.61 | GO_MONOSACCHARIDE_CATABOLIC_PROCESS | MSigDB lists | GO_MONOSACCHARIDE_CATABOLIC_PROCESS | 55 | 11 | 15632 | 1249 |
Pfkfb3,Fut8,Pgk1,Hk2,Pfkl,Hk3,Hk1,Tpi1,Eno2,Eno1,Pgm1 |
| 3.679e-03 | -5.61 | SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_DN | MSigDB lists | SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_DN | 55 | 11 | 15632 | 1249 |
Cd180,Rhoh,H2-Q7,Itga4,Dnase1l3,Inpp1,Traf5,H2-Q6,Gpr18,H2-Q4,Cd69 |
| 3.681e-03 | -5.60 | JOHNSTONE_PARVB_TARGETS_2_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_DN | 293 | 37 | 15632 | 1249 |
Hivep3,Rnf19a,Ahrr,Cdyl,Dach1,Fubp1,Gcnt2,Rap2c,Clic4,Frmd6,Sec24b,Esd,Slc31a1,Etnk1,Ptk2,Slc44a1,Ubtd2,1110038F14Rik,Nr3c1,Casp3,B3gnt5,Hdac1,Ifrd1,Rin2,Plekha5,Cst7,Tpst1,Dock4,Ttc39c,Atp11b,Angpt1,Pdgfc,Enpp4,Gbe1,Xrn1,Dcp2,Nmral1 |
| 3.682e-03 | -5.60 | sex differentiation | biological process | GO:0007548 | 274 | 31 | 20694 | 1406 |
Icam1,Ahr,Pbx1,Ccnd1,Nupr1,Serpine1,Inhba,Gja1,Itgav,Fndc3a,Crkl,Hmga2,Axl,Sirt1,Insl6,Arid5b,Tiparp,Serpinb6b,Nos2,Stat5a,Kitl,Arid4a,Kdr,Cited2,Atm,Pla2g4a,Dach1,Src,Bcl2l11,Angpt1,H3f3b |
| 3.685e-03 | -5.60 | YIH_RESPONSE_TO_ARSENITE_C5 | MSigDB lists | YIH_RESPONSE_TO_ARSENITE_C5 | 9 | 4 | 15632 | 1249 |
Map2k1,Ccl12,Pml,Plau |
| 3.685e-03 | -5.60 | SA_FAS_SIGNALING | MSigDB lists | SA_FAS_SIGNALING | 9 | 4 | 15632 | 1249 |
Casp8,Cflar,Casp3,Fas |
| 3.685e-03 | -5.60 | GO_NEGATIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | 9 | 4 | 15632 | 1249 |
Ppp1r15b,Bfar,Nck1,Ppp1r15a |
| 3.685e-03 | -5.60 | GO_CXCR_CHEMOKINE_RECEPTOR_BINDING | MSigDB lists | GO_CXCR_CHEMOKINE_RECEPTOR_BINDING | 9 | 4 | 15632 | 1249 |
Cxcl1,Pf4,Cxcl2,Cxcl10 |
| 3.685e-03 | -5.60 | PID_VEGF_VEGFR_PATHWAY | MSigDB lists | PID_VEGF_VEGFR_PATHWAY | 9 | 4 | 15632 | 1249 |
Vegfc,Nrp2,Flt1,Kdr |
| 3.685e-03 | -5.60 | OXFORD_RALA_TARGETS_UP | MSigDB lists | OXFORD_RALA_TARGETS_UP | 9 | 4 | 15632 | 1249 |
Asns,Cxcl1,Slc7a11,Dusp6 |
| 3.685e-03 | -5.60 | BIOCARTA_FREE_PATHWAY | MSigDB lists | BIOCARTA_FREE_PATHWAY | 9 | 4 | 15632 | 1249 |
Gsr,Nox1,Tnf,Nfkb1 |
| 3.685e-03 | -5.60 | VANLOO_SP3_TARGETS_UP | MSigDB lists | VANLOO_SP3_TARGETS_UP | 9 | 4 | 15632 | 1249 |
Itga4,Nupr1,Serpinb2,Trib3 |
| 3.685e-03 | -5.60 | GO_PEPTIDOGLYCAN_BINDING | MSigDB lists | GO_PEPTIDOGLYCAN_BINDING | 9 | 4 | 15632 | 1249 |
Nod2,Nlrp3,Tlr2,Nod1 |
| 3.695e-03 | -5.60 | GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 140 | 21 | 15632 | 1249 |
Wdr43,Lrp11,Prdx1,Batf,Mcm6,Tlr2,Sdc1,Denr,Hmox1,Pcgf5,Plk3,Psma6,Cpd,Csf1,Irf4,Nrp2,Homer1,Sod2,Csrp1,Tmem200b,Nampt |
| 3.701e-03 | -5.60 | BROWNE_HCMV_INFECTION_24HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_DN | 131 | 20 | 15632 | 1249 |
Lpar1,Nr1h3,Cflar,Rras2,Sgcb,Actb,Thbs1,Crim1,Atp2b4,Cdkn1a,Angpt1,Abcc1,Sema3c,Cav1,Pdgfrb,Ext1,Pdlim7,Bst1,Rin2,Met |
| 3.701e-03 | -5.60 | GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | MSigDB lists | GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 131 | 20 | 15632 | 1249 |
Kdr,Hcls1,Kitl,Cd80,Jak2,Angpt1,Pdgfc,Ptk2,Fgr,Pik3cd,Ier3,Irs2,Pdgfb,Rasgrp1,Sirt1,Csf3,Ccl5,Flt1,Pdgfrb,Cd86 |
| 3.704e-03 | -5.60 | SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_DN | MSigDB lists | SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_DN | 33 | 8 | 15632 | 1249 |
Socs1,Arid5a,Socs3,Stat1,Stat5a,Arid4a,Igf1r,Kitl |
| 3.704e-03 | -5.60 | GO_LUMENAL_SIDE_OF_MEMBRANE | MSigDB lists | GO_LUMENAL_SIDE_OF_MEMBRANE | 33 | 8 | 15632 | 1249 |
Cd74,H2-Q6,H2-Eb1,H2-Q4,H2-Q7,H2-Ab1,Tapbp,H2-Aa |
| 3.704e-03 | -5.60 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_UP | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_UP | 33 | 8 | 15632 | 1249 |
H2-Aa,Rras2,Cd83,Rab21,Maff,Stat4,Nampt,Map2k4 |
| 3.704e-03 | -5.60 | GO_LYMPHOCYTE_CHEMOTAXIS | MSigDB lists | GO_LYMPHOCYTE_CHEMOTAXIS | 33 | 8 | 15632 | 1249 |
Ccl12,Ccl5,Ccl22,Cxcl10,Cx3cl1,Pik3cd,Ccl2,Ccl3 |
| 3.704e-03 | -5.60 | PID_EPO_PATHWAY | MSigDB lists | PID_EPO_PATHWAY | 33 | 8 | 15632 | 1249 |
Jak2,Irs2,Lyn,Nfkb1,Stat1,Socs3,Crkl,Stat5a |
| 3.704e-03 | -5.60 | WEIGEL_OXIDATIVE_STRESS_BY_TBH_AND_H2O2 | MSigDB lists | WEIGEL_OXIDATIVE_STRESS_BY_TBH_AND_H2O2 | 33 | 8 | 15632 | 1249 |
Spint2,Tcea1,Hdac1,Slc7a5,Vcam1,Actb,Zyx,Itgal |
| 3.704e-03 | -5.60 | PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP | MSigDB lists | PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP | 33 | 8 | 15632 | 1249 |
Aoah,Atp10a,S100a8,Tlr3,Cxcl1,Il1b,Cebpd,Cd38 |
| 3.724e-03 | -5.59 | ARPC1B (actin related protein 2/3 complex subunit 1B) | protein interactions | 10095 | 12 | 5 | 7778 | 753 |
Tmod3,Kif3c,Cenpe,Itga5,Actb |
| 3.731e-03 | -5.59 | GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_NONATOPIC_PATIENT_DN | MSigDB lists | GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_NONATOPIC_PATIENT_DN | 177 | 25 | 15632 | 1249 |
Tiparp,Syk,Gramd1a,Dync1h1,Gadd45b,Hivep2,Kdm5b,Ap3b1,Arl4a,Isg15,Usp25,Atp11b,Tnks1bp1,Hinfp,Adap2,Junb,Tdrd7,Rasgrp1,Snx2,Prdm9,Ap3m2,Plaur,Tmem123,Rap2c,Tax1bp1 |
| 3.731e-03 | -5.59 | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_DN | 177 | 25 | 15632 | 1249 |
Mmp9,Slc31a1,Adora2b,Clcn7,Serpinb2,Kitl,Fam162a,Txn1,Dach1,Myo1b,Slpi,Il18rap,Nfkbiz,Itga4,Rtp4,Dtwd1,Cd83,Cutc,Cd14,Chmp4b,Axl,Ppp1r14b,D16Ertd472e,Pde1b,B3gnt5 |
| 3.731e-03 | -5.59 | GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_1_DN | MSigDB lists | GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_1_DN | 177 | 25 | 15632 | 1249 |
Gadd45b,Slc44a1,Nmi,Aftph,Scn1b,Stx11,Ift57,Mmp9,Lif,Ell2,Csrnp1,Palld,Fam53c,Mxd1,Pgs1,Tapbpl,Ubash3b,Icam1,Rgs1,Ccdc88b,Trp53i11,Sdc4,F10,Frmd6,Plagl2 |
| 3.731e-03 | -5.59 | GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_UP | MSigDB lists | GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_UP | 177 | 25 | 15632 | 1249 |
Tmem229b,Acvr1b,Sec24b,Wdr43,Tmem123,Bcl2a1a,Sik3,Dusp6,Jarid2,4930523C07Rik,Stat4,Ksr1,Pgm1,Trim13,Fas,Nfkbil1,Hvcn1,Ahsa1,Ifnar1,Bcl2a1b,Gsdmd,Bcl2a1d,Kdm5b,Mllt6,Irf4 |
| 3.731e-03 | -5.59 | GSE14308_TH2_VS_TH17_UP | MSigDB lists | GSE14308_TH2_VS_TH17_UP | 177 | 25 | 15632 | 1249 |
Cenpe,Pik3r5,Casp3,Errfi1,Dtnb,Rsad2,Nmral1,Gmppb,Il4ra,Enpp4,Lgals9,Sik3,Sipa1l1,Lap3,Rrs1,Tlr1,Rap1gap2,Tdrd7,Ak4,Pik3cd,Gpd2,Osbpl3,Elmod2,Tax1bp1,Glrx |
| 3.738e-03 | -5.59 | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | MSigDB lists | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | 96 | 16 | 15632 | 1249 |
Kat2b,Plk3,Stat1,Jak2,Rbbp8,Lmo4,Atm,Junb,Nfkbia,Stat5a,Ccne1,Ccnd1,Hdac1,Mdm2,Nmi,Myc |
| 3.750e-03 | -5.59 | GO_PARTURITION | MSigDB lists | GO_PARTURITION | 20 | 6 | 15632 | 1249 |
Mmp13,Maff,Edn1,Ptafr,Ptger4,Ccl12 |
| 3.750e-03 | -5.59 | GO_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | MSigDB lists | GO_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | 20 | 6 | 15632 | 1249 |
Jun,Bcl2a1d,Bcl2a1b,Sod2,Bcl2a1a,Ggct |
| 3.750e-03 | -5.59 | MANN_RESPONSE_TO_AMIFOSTINE_UP | MSigDB lists | MANN_RESPONSE_TO_AMIFOSTINE_UP | 20 | 6 | 15632 | 1249 |
Mdm2,Gsr,Cdkn1a,Myc,Casp4,Gdf15 |
| 3.750e-03 | -5.59 | KIM_GERMINAL_CENTER_T_HELPER_DN | MSigDB lists | KIM_GERMINAL_CENTER_T_HELPER_DN | 20 | 6 | 15632 | 1249 |
Dusp8,Usp12,Rap1gap2,Ell2,Irs2,Dock4 |
| 3.750e-03 | -5.59 | MODULE_439 | MSigDB lists | MODULE_439 | 20 | 6 | 15632 | 1249 |
Bcl2a1d,Bcl2a1a,Ier3,Lap3,Bcl2a1b,Nfkb1 |
| 3.750e-03 | -5.59 | GO_POSITIVE_REGULATION_OF_TRANSLATIONAL_INITIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSLATIONAL_INITIATION | 20 | 6 | 15632 | 1249 |
Polr2g,Ythdf1,Ccl5,Tnf,Nck1,Ppp1r15a |
| 3.750e-03 | -5.59 | GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION_OF_STAT_PROTEIN | MSigDB lists | GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION_OF_STAT_PROTEIN | 20 | 6 | 15632 | 1249 |
Ifna2,Ifna5,Ifnb1,Lif,Ifna6,Ifna1 |
| 3.750e-03 | -5.59 | NIKOLSKY_OVERCONNECTED_IN_BREAST_CANCER | MSigDB lists | NIKOLSKY_OVERCONNECTED_IN_BREAST_CANCER | 20 | 6 | 15632 | 1249 |
Nfkb1,Stat1,Irf8,Stat4,Kdm5b,Etv5 |
| 3.750e-03 | -5.59 | GO_MAST_CELL_ACTIVATION | MSigDB lists | GO_MAST_CELL_ACTIVATION | 20 | 6 | 15632 | 1249 |
Nr4a3,Rasgrp1,Pik3cd,Lyn,Lcp2,Rhoh |
| 3.750e-03 | -5.59 | STAT3_01 | MSigDB lists | STAT3_01 | 20 | 6 | 15632 | 1249 |
Cish,Maff,Apba1,Ccl12,Irf1,Icam1 |
| 3.753e-03 | -5.59 | GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | MSigDB lists | GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | 71 | 13 | 15632 | 1249 |
Tlr2,Cd55,Fas,H2-Ab1,Traf3ip2,Trem1,Batf,Swap70,H2-Eb1,Nod2,Sirt1,Pou2f2,Dennd1b |
| 3.753e-03 | -5.59 | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP | 71 | 13 | 15632 | 1249 |
Lhx2,Nxf1,Atf3,Pim2,Cebpd,Nat2,Alas1,Cnp,Ifit1bl1,Ifit1bl2,Tuba4a,Brd2,Srm |
| 3.767e-03 | -5.58 | ZAMORA_NOS2_TARGETS_UP | MSigDB lists | ZAMORA_NOS2_TARGETS_UP | 63 | 12 | 15632 | 1249 |
Ppp1r14b,Srm,Csrp1,Ccne1,Hsph1,Pnp2,Ifrd1,Hmox1,Ppa1,Ier2,Mcm6,Il1rn |
| 3.801e-03 | -5.57 | neuronal cell body | cellular component | GO:0043025 | 709 | 67 | 20747 | 1409 |
Ptger4,Igf1r,Fabp7,Acvrl1,Cx3cl1,Txn1,Casp4,Kcnj2,Pde1b,Met,Fas,Itpr1,Eno2,Tnfrsf1b,Txnrd1,Cacna1d,Dync1h1,Kdr,Palld,Prkar2b,Hdc,Adora2a,Rac3,Flnb,Xrn1,Htr2b,Ass1,Plk3,Itga4,Sdc2,Slc31a1,Cyfip1,Uchl1,Optn,Cx3cr1,Gpc1,Hdac1,Homer1,Kif5c,Kremen1,Cd40,Glrx,Rapgef2,Lrp4,Stau1,Map2k4,Cdk5r1,Adrb2,Lpar1,Ccl2,Lrp8,Magohb,Tpx2,Sipa1l1,Cd200,Pdgfb,Kif3c,Myo10,Map2k1,Ccr1,Tnf,Nqo1,Casp3,Katna1,Htr2a,Mul1,Cnn3 |
| 3.812e-03 | -5.57 | neural crest cell development | biological process | GO:0014032 | 83 | 13 | 20694 | 1406 |
Sema4c,Hif1a,Edn1,Htr2b,Phactr4,Cited2,Jag1,Kitl,Ednrb,Nrp2,Sema3c,Acvr1,Sema4a |
| 3.812e-03 | -5.57 | regulation of cell junction assembly | biological process | GO:1901888 | 83 | 13 | 20694 | 1406 |
Mmp14,Ptk2,Sdc4,Ptprj,Map4k4,Rapgef2,Src,Fzd5,Acvrl1,Cav1,Tnf,Kdr,Gja1 |
| 3.828e-03 | -5.57 | GSE40655_FOXO1_KO_VS_WT_NTREG_DN | MSigDB lists | GSE40655_FOXO1_KO_VS_WT_NTREG_DN | 168 | 24 | 15632 | 1249 |
Ell2,Cd200,Rcn1,Agpat4,Ccl5,Psat1,Pdk3,Plek,Tnfsf14,Ppp2r3a,Smpdl3b,Car13,Nek6,Fas,Nmral1,Rbms2,Ppfibp1,Insl6,Ehd1,Hspa1a,Slc44a1,Egr2,Dhx58,Mdm2 |
| 3.828e-03 | -5.57 | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN | 168 | 24 | 15632 | 1249 |
Mpp7,Cdkn2d,Tlr6,Itga4,Tle3,Klf7,Hvcn1,Fcgr1,P2ry13,Bcl6,Psmb9,Nr4a1,Fgl2,Prkce,Ifi44,Asb13,Mmp25,Mppe1,Tmem219,Rbms1,Klf2,Stx11,Il12rb1,Zfp36 |
| 3.847e-03 | -5.56 | EPHD | prosite domains | PS51805 | 27 | 7 | 13278 | 1037 |
Kdm4a,Phf11b,Phf6,Mllt6,Phf11a,Phf11d,Phf11c |
| 3.863e-03 | -5.56 | E3_UB_ligase_RBR | interpro domains | IPR031127 | 10 | 4 | 19984 | 1430 |
Rnf19b,Ankib1,Rnf14,Rnf19a |
| 3.863e-03 | -5.56 | RHD_dimer | interpro domains | IPR032397 | 10 | 4 | 19984 | 1430 |
Nfkb1,Relb,Nfkb2,Rel |
| 3.863e-03 | -5.56 | RHD_DNA_bind_dom_sf | interpro domains | IPR037059 | 10 | 4 | 19984 | 1430 |
Nfkb1,Relb,Nfkb2,Rel |
| 3.863e-03 | -5.56 | RHD_DNA_bind_dom | interpro domains | IPR011539 | 10 | 4 | 19984 | 1430 |
Rel,Nfkb2,Nfkb1,Relb |
| 3.885e-03 | -5.55 | GO_GOLGI_MEMBRANE | MSigDB lists | GO_GOLGI_MEMBRANE | 648 | 71 | 15632 | 1249 |
Lpcat2,Rnd3,St3gal3,Pikfyve,Cyth3,Sgms2,Aftph,Ctsc,Irgm2,Chst11,Optn,H2-Q4,B4galt4,Ust,Gbp2b,Whamm,Notch2,Pmepa1,Tlr9,St3gal5,Rasgrp1,Rhou,Stx6,Cav1,Gbp2,Notch1,Pdgfc,Clcn5,H2-Q7,Agtrap,Gbp3,St3gal6,Cd74,Slc39a13,Dbnl,Rab9,Rnf24,Rhoq,Rffl,Rab21,Fut8,B3gnt5,Tapbp,Glipr2,Ppp6r1,Slc2a1,Tpst1,Mgat1,H2-Q6,Dse,Sec24a,Gcnt2,Sec24b,Il15ra,Fndc3a,H2-Ab1,St3gal1,Cd55,Tlr3,Tapbpl,Gbgt1,H2-Aa,Ext1,Pdgfb,Rab10,Gja1,H2-Eb1,Golga3,Vps54,Myo1b,Fzd5 |
| 3.909e-03 | -5.54 | B cell activation involved in immune response | biological process | GO:0002312 | 47 | 9 | 20694 | 1406 |
Dock10,Cd180,Ifnb1,Notch2,Tnfaip3,Icosl,Batf,Swap70,Plcl2 |
| 3.909e-03 | -5.54 | regulation of release of cytochrome c from mitochondria | biological process | GO:0090199 | 47 | 9 | 20694 | 1406 |
Bnip3,Tnfsf10,Mmp9,Bcl2l11,Higd1a,Fam162a,Psmd10,Fas,Plaur |
| 3.909e-03 | -5.54 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | GO:1902041 | 47 | 9 | 20694 | 1406 |
Hmox1,Icam1,Tnfaip3,Atf3,Rffl,Serpine1,Cflar,Rnf34,Thbs1 |
| 3.909e-03 | -5.54 | positive regulation of vasoconstriction | biological process | GO:0045907 | 47 | 9 | 20694 | 1406 |
Icam1,Ptgs2,Cav1,Ptafr,Gja1,Htr2a,Pdgfb,Cd38,Pde5a |
| 3.909e-03 | -5.54 | negative regulation of epithelial cell differentiation | biological process | GO:0030857 | 47 | 9 | 20694 | 1406 |
Cav1,Notch1,Jag1,Il1a,Ccnd1,Zeb1,Foxp4,Mmp9,Acvrl1 |
| 3.909e-03 | -5.54 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological process | GO:2001239 | 47 | 9 | 20694 | 1406 |
Cx3cl1,Il1b,Tnf,Eya4,Cx3cr1,Inhba,Sgk3,Ppp2r1b,Pf4 |
| 3.911e-03 | -5.54 | phosphoprotein phosphatase activity | molecular function | GO:0004721 | 172 | 22 | 20217 | 1400 |
Dusp5,Dusp8,Ubash3b,Dusp16,Ppm1k,Dusp28,Ptprj,Phlpp1,Eya4,Mtmr14,Ppp2r5a,Phlpp2,Ppm1l,Dusp2,Ppp2r2a,Dusp6,Acp2,Ptpn2,Ppp2r1b,Dusp4,Dusp14,Dusp1 |
| 3.919e-03 | -5.54 | cytoplasmic ribonucleoprotein granule | cellular component | GO:0036464 | 197 | 24 | 20747 | 1409 |
Ago3,Psma6,Ddx4,Actb,Larp1,Mov10,Trim12c,Socs1,Carhsp1,Icosl,Dcp1a,Dcp2,Tdrd7,Stau1,Rbpms,Zc3h12a,G3bp2,Sqstm1,Noct,Polr2g,Nfkbiz,Xrn1,Zfp36,Kif3c |
| 3.922e-03 | -5.54 | Jak1 (Janus kinase 1) | protein interactions | 16451 | 17 | 6 | 7778 | 753 |
Lmo4,Stat3,Socs3,Socs1,Ptpn2,Stat5a |
| 3.926e-03 | -5.54 | cell junction | cellular component | GO:0030054 | 1119 | 99 | 20747 | 1409 |
Nectin2,Keap1,Lcp2,Vezt,Ezr,Itgal,Palld,Kctd12,Nectin4,Nox1,Nck1,Pkp4,Pvr,Ccnd1,Jak2,Znrf1,Rims3,Agrn,Myadm,Cav1,Rnd1,Gja1,Itga5,Pdlim7,Pikfyve,Rhou,Ddx58,Mpp7,Dmxl2,Dcp2,Pdzd11,Frmd4a,Cyth3,Ptprj,Clic4,Flrt3,Cpeb4,Syne2,Notch1,Rpgrip1l,Itgb8,Usp53,Mtdh,Htr2b,Dst,Ptk2,Slc7a2,Zyx,Scn1b,Flnb,Nampt,Sphk1,Dbnl,Kdr,Hap1,Irf2,Arhgap26,Slc2a1,Fchsd2,Tnks1bp1,Pdpn,Rai14,Nlgn2,Kcnj2,Prag1,Map4k4,F11r,Fabp7,Slc9a1,Fzd5,Micall2,Smc5,Asap3,Slc16a1,Map2k1,Abcb1a,Hcar2,Sipa1l1,Vasp,Itgav,Igsf9,Evl,Jag1,Rapgef2,Sema4c,Homer1,Fscn1,Mmp13,Rgs14,Cdc42ep4,Hck,Flrt2,Cyfip1,Clmp,Lyn,Itga4,Sdc4,Frmd6,Rap2c |
| 3.943e-03 | -5.54 | biological adhesion | biological process | GO:0022610 | 798 | 74 | 20694 | 1406 |
Pcdh7,Thbs1,Cd34,Spn,Whamm,Bcl2l11,Plek,Src,Micall2,Pvr,Tgfbi,Gbp3,Dst,Itga5,Vcan,Gbp2b,Olr1,Itgal,Palld,Itga9,Lgals9,Axl,Cd164,Sele,Scarf1,Il1b,Itgav,F11r,Flrt3,Sell,Slc7a11,Tnip1,Cd200,Cdk5r1,Prkce,Gbp2,Angpt1,Cx3cr1,Siglece,S100a8,Zyx,Acvr1,Vezt,Plpp3,Syk,Ubash3b,Gbp7,Stxbp1,Tnc,Gbp9,Klra2,Kitl,P2ry12,Cx3cl1,Pdpn,Tnf,Itga4,Nectin4,Itgb8,Prkx,Nectin2,Antxr1,Nlgn2,Fndc3a,Ntng2,Csf3r,Stxbp3,Vcam1,Igsf9,Col18a1,Flrt2,Ccl5,Pkp4,Icam1 |
| 3.948e-03 | -5.53 | glycerophospholipid metabolic process | biological process | GO:0006650 | 208 | 25 | 20694 | 1406 |
Mecp2,Atm,Inpp1,Pgap2,Socs3,Plaat3,Inpp5b,Socs1,Etnk1,Pik3cd,Plscr1,Cept1,Pgs1,Pigv,Plek,Pikfyve,Dgka,Pla2g4a,Dgkh,Socs7,Cish,Pla2g7,Pdgfrb,Mppe1,Lpcat2 |
| 3.959e-03 | -5.53 | RHD_dimer | pfam domains | PF16179 | 10 | 4 | 18711 | 1348 |
Nfkb1,Rel,Nfkb2,Relb |
| 3.959e-03 | -5.53 | WWE | pfam domains | PF02825 | 10 | 4 | 18711 | 1348 |
Parp11,Parp12,Dtx2,Zc3hav1 |
| 3.959e-03 | -5.53 | RHD_DNA_bind | pfam domains | PF00554 | 10 | 4 | 18711 | 1348 |
Nfkb2,Rel,Nfkb1,Relb |
| 3.961e-03 | -5.53 | glucose metabolic process | biological process | GO:0006006 | 93 | 14 | 20694 | 1406 |
Pfkl,Hk2,Myc,Ldha,Serp1,Pgm1,Atf3,Pcx,Tpi1,Pgk1,Hk1,Pdk3,Tnf,Gpd2 |
| 3.970e-03 | -5.53 | actin filament | cellular component | GO:0005884 | 123 | 17 | 20747 | 1409 |
Tmod3,Mark2,Keap1,Pdlim7,Src,Rhoq,Ezr,Hck,Gng12,Carmil1,Dbnl,Tpm4,Hcls1,Myo1b,Rac3,Pstpip2,Palld |
| 3.978e-03 | -5.53 | DURAND_STROMA_NS_UP | MSigDB lists | DURAND_STROMA_NS_UP | 150 | 22 | 15632 | 1249 |
Arhgap26,Rbpms,Ampd3,Ctsc,Itpr1,Slc16a3,Gdf15,Pik3r5,Dusp6,Insl6,Gch1,Ezr,Map3k6,Hivep2,Olr1,Dusp16,Pde3b,Nod1,Mpp7,Phyh,Prrg4,Aim2 |
| 3.978e-03 | -5.53 | PKCA_DN.V1_DN | MSigDB lists | PKCA_DN.V1_DN | 150 | 22 | 15632 | 1249 |
Cp,Dennd1b,Map3k6,Plau,Zfp319,Pdgfc,Enpp4,Nfkbiz,Slc30a1,Etv3,Tifa,Procr,Ext1,Hk2,Psat1,Pdgfrb,Myo1b,Nfil3,Zc3h12a,Tlr2,Clec4d,Trib1 |
| 3.985e-03 | -5.53 | Ube2i (ubiquitin-conjugating enzyme E2I) | protein interactions | 22196 | 28 | 8 | 7778 | 753 |
Fas,Mdm2,Jun,Dach1,Hif1a,Irf8,Irf2,Irf1 |
| 3.995e-03 | -5.52 | negative regulation of autophagy | biological process | GO:0010507 | 74 | 12 | 20694 | 1406 |
Stat3,Ptk2,Il10,Nampt,Chmp4b,Eif4g2,Kdm4a,Htr2b,Tspo,Tnfaip3,Nupr1,Hmox1 |
| 3.997e-03 | -5.52 | cytoskeleton | cellular component | GO:0005856 | 2076 | 171 | 20747 | 1409 |
Sele,Cnp,Spry2,Frmd4a,Kif9,Mvp,Swap70,Resf1,Dnaja1,Ccdc88b,Syne2,Tmod3,Dync1i2,Mdn1,Clic4,Prkar2b,Gng12,Myo1b,Dync1h1,Dyrk2,Mark2,Keap1,Src,Pde4b,Ctsc,Fcho2,Hsph1,Marcksl1,Daam1,Atm,Rnd1,Mtus1,Myadm,Hspa2,Prkce,Ikbkg,Jak2,Rgcc,Rnf19a,Mefv,Tulp3,Ift22,Tpx2,Smg7,Ubr4,Zc3h12a,Gypc,Gpsm2,Nr3c1,Map2k1,Myo10,Fcgr2b,Lad1,Clmp,Ppp2r5a,Kif5c,Tyk2,Fnbp1l,Pik3r5,Rmdn3,Sbds,Cnn2,Mecp2,Ppp4r2,Ift57,Cenpj,Cep350,Nes,Pcgf5,Hap1,Dst,Rab3ip,Plk3,Snx10,Flnb,Zyx,Atp6v1d,Intu,Ddx60,Mapkapk2,Sgcb,Myc,Igf2bp2,Tnks1bp1,Rai14,Rap1gap2,Clic5,Tlk2,Mapkbp1,Ccne1,Tmem67,Pdlim7,Gja1,Cnn3,Trim36,Ddx58,Gbp2,Rpgrip1l,Slc7a11,Spire1,Actb,S100a8,Stxbp1,Cdc42ep2,Plk2,Adora2a,Hcls1,Hspa1a,Pkp4,Cenpe,Palld,Ezr,Dennd2a,Cep85l,Nod2,Plekhn1,Ppp1r12b,Csrp1,Kat2b,Sass6,Relb,Rims3,Kitl,Uaca,Vasp,Evl,Tpm4,Lrp8,Sipa1l1,Rilpl1,Gem,Traf5,Tap1,Pstpip2,Slc16a1,Katna1,Mid1,Kif3c,Triobp,Ripk2,Flt1,Nlrc5,Procr,Nek6,Mmp14,Frmd6,Daxx,Rhof,Fscn1,Rhoq,Hck,Cdc42ep4,Rgs14,Tuba4a,Dbnl,Carmil1,Rac3,Marcks,Whamm,Psmd10,Ptk2,Fgr,Ncoa5,Bcl2l11,Trip10,Nos2,Micall2,Vcam1,Slc2a1,Arhgap26,Serp1 |
| 4.016e-03 | -5.52 | GGGAGGRR_MAZ_Q6 | MSigDB lists | GGGAGGRR_MAZ_Q6 | 2059 | 196 | 15632 | 1249 |
Sp140,Gypc,Src,Slc2a1,Itpr1,Dusp8,Fchsd2,Egr2,Fut8,Ccnd1,Lif,Socs1,Sertad3,Kdm4a,Smg7,Notch1,Sesn3,Arid4a,Jarid2,Rgl1,Igsf8,Daam1,Pdgfb,Adora2a,Csf3,Ptafr,Kcna3,Serpinb2,Plaur,Trmt1l,Tagln,Map3k6,Dock4,Fos,Prkce,Ppfia3,Cxcl14,Egr1,Arrdc4,Nkiras1,Ccnd2,Cdc42ep2,Tnks1bp1,P4ha1,Ccne1,Eif4g2,Mier3,Ubr4,Hat1,Jag1,Denr,Mtmr14,Actb,Nlgn2,Agpat4,Phldb1,Slc25a37,Tcf4,Ankrd17,Mtus1,Stat3,Prdx5,Rbpms,Glipr2,Aebp2,Csrnp1,Plk3,Pigv,Tab2,Slc39a13,Brwd3,Osm,Fzd5,Parp12,St3gal1,Nr4a3,Il18,Cdc42ep4,Map3k8,Plat,Ralgds,Pcdh7,Stip1,Pkp4,Psip1,Gadd45b,Hmga1,Trip10,Mmp14,Scarf1,Gadd45g,S1pr2,Mllt6,Bcor,Tpi1,Nr1h3,Cx3cl1,Dusp14,Lmo4,Mov10,Atxn7l1,Rtn2,Zeb1,Cnn3,Syne2,Slamf9,Egr3,Ust,Col27a1,Rbms1,Znrf1,Lipe,Acvr1,Bmp2,Rhoc,Daxx,Junb,Slc7a8,Slc13a3,Tnfsf15,Stx11,G3bp2,Ptprj,Pim1,Il1rn,Nfkbia,Jun,Cyfip1,Slc44a1,Myc,Mark2,Clic5,Dach1,Lcn2,Bcl9,Pla2g7,Etnk1,Mafg,Prkar2b,Igf1r,Serp1,Itgb8,Phgdh,Rab21,Ccng2,Dhx58,Errfi1,Tlk2,Hdac1,Etv5,Rgs3,Brd2,Myadm,Dusp6,Gdf15,Ttc9c,Fosb,Col11a2,Tmeff1,Rab10,Vasp,Vasn,Slc25a12,St7,Phf6,Nfkb2,Gtpbp2,Ass1,Dnaja1,Casz1,Fcgr2b,Tor1aip2,Dusp4,Cnot4,Vcan,Psd,Col18a1,Nck1,Sdc1,Trp53i11,Tle3,Gem,Med13,Mmd,Itga5,Max,Sema4c,Trib1,Adam19,Ldlr,Rap2c,Arf4,Jak2,Cdkn1a,Lrrc8c,H3f3b |
| 4.021e-03 | -5.52 | GSE14308_TH17_VS_INDUCED_TREG_DN | MSigDB lists | GSE14308_TH17_VS_INDUCED_TREG_DN | 178 | 25 | 15632 | 1249 |
Traf2,B4galt4,Errfi1,Psd,Taf4b,Phactr4,Cers6,Ythdf1,Cp,Rnf24,Arl4a,Spred1,Chmp4b,Rbl1,Ccdc88b,Marco,Oas1a,Il12rb1,Arl5b,Egr3,Oas1g,Stat1,Ppfibp2,Cdkn1a,Tnip1 |
| 4.021e-03 | -5.52 | GSE13229_IMM_VS_INTMATURE_NKCELL_DN | MSigDB lists | GSE13229_IMM_VS_INTMATURE_NKCELL_DN | 178 | 25 | 15632 | 1249 |
Casp7,Dnaja2,Lrrc8c,Clcn7,Rsbn1,Ppm1k,Ccnj,Hk1,Sirt1,Slc39a13,Ccnd2,Nkiras1,Cd180,Prdm1,Usp25,Olr1,Slc28a2,Bfar,Gpc1,Ccdc88b,Ifit2,Abcc5,Syk,Gclm,Ppp2r5a |
| 4.021e-03 | -5.52 | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_UP | MSigDB lists | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_UP | 178 | 25 | 15632 | 1249 |
Ms4a6d,Rcn1,Parp3,Vasn,Bst1,Ampd3,Ppp4r2,Fubp1,Abtb2,Rab3ip,Crim1,Slc16a1,Usp18,Aldh1b1,Sell,Nfkbil1,Nupr1,Cdyl2,Mdn1,Myc,Egr2,Tspan3,B4galt4,Trip10,Spsb1 |
| 4.021e-03 | -5.52 | GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_DN | MSigDB lists | GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_DN | 178 | 25 | 15632 | 1249 |
Syne2,Lap3,Ptch1,Ankib1,Snx10,Lacc1,Igf1r,Abcc4,Rbms1,Mob3b,Acsl1,Ebi3,Kpna3,Ptger4,Dusp5,Gsr,Phgdh,Pla2g4a,Dse,Arid5a,Homer1,Bcl6,Pfkfb3,Ccnd2,Tmem176b |
| 4.021e-03 | -5.52 | GSE30083_SP1_VS_SP4_THYMOCYTE_UP | MSigDB lists | GSE30083_SP1_VS_SP4_THYMOCYTE_UP | 178 | 25 | 15632 | 1249 |
Pdzd11,Trib1,Uchl1,Mmp9,Agpat4,Plod2,Dmwd,Rrs1,Tuba4a,Hsd17b12,Eno2,Hivep3,Scn1b,Cnn3,Marcksl1,Slc30a4,Spred1,Etv5,Gpc1,Abcc5,Armcx6,Ift57,Lztfl1,Ubtd2,Ccdc86 |
| 4.021e-03 | -5.52 | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN | MSigDB lists | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN | 178 | 25 | 15632 | 1249 |
Dhx58,Rsad2,Arhgap26,Katna1,Agrn,Etv5,Clec4e,Lpcat2,Rnd3,Palld,Plk3,Xaf1,Eef1e1,Stxbp3,Nfkbib,Trim14,Pstpip2,Col11a2,Dusp6,Slc7a8,Cmpk2,Gfi1,Tfec,Irak2,Map3k8 |
| 4.024e-03 | -5.52 | GSE14415_INDUCED_TREG_VS_TCONV_DN | MSigDB lists | GSE14415_INDUCED_TREG_VS_TCONV_DN | 141 | 21 | 15632 | 1249 |
Spry2,Rasgrp1,B3gnt5,Kdm5b,Card6,Klf3,Junb,Otud1,Ttc39c,Dnajb2,Klf7,Crim1,Prrg4,Bcor,Cd55,Adrb2,Traf1,Slco3a1,Ccnd2,Mppe1,Trim13 |
| 4.029e-03 | -5.51 | regulation of carbohydrate biosynthetic process | biological process | GO:0043255 | 103 | 15 | 20694 | 1406 |
Il6,Pdgfb,Ptger4,Hif1a,Gfpt1,Ptafr,Kat2b,Irs2,Nfkb1,Nr3c1,Ptpn2,Plek,Sirt1,Dyrk2,Ranbp2 |
| 4.031e-03 | -5.51 | DARWICHE_SKIN_TUMOR_PROMOTER_UP | MSigDB lists | DARWICHE_SKIN_TUMOR_PROMOTER_UP | 123 | 19 | 15632 | 1249 |
Slpi,S100a8,Axl,Plac8,Srm,Plekha4,Traf2,Spic,Cited2,Eno1,Pfkl,Esd,Cmpk2,Pgk1,Rhoh,Ldha,Lif,Icam1,Cx3cl1 |
| 4.031e-03 | -5.51 | GO_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT | MSigDB lists | GO_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT | 123 | 19 | 15632 | 1249 |
Atf3,Hlx,Egr1,Nupr1,Plagl1,Cflar,Notch1,Ass1,Homer1,Fos,Cav1,Igsf8,Bcl9,Sap30,Btg2,Egr2,Flnb,Hivep3,Maff |
| 4.044e-03 | -5.51 | EGFR tyrosine kinase inhibitor resistance | KEGG pathways | mmu01521 | 79 | 15 | 7931 | 713 |
Pdgfrb,Bcl2l11,Kdr,Stat3,Jak2,Axl,Il6,Met,Map2k1,Pik3cd,Src,Akt3,Pdgfc,Pdgfb,Igf1r |
| 4.044e-03 | -5.51 | EGFR tyrosine kinase inhibitor resistance | KEGG pathways | ko01521 | 79 | 15 | 7931 | 713 |
Igf1r,Pdgfc,Pdgfb,Akt3,Src,Il6,Stat3,Axl,Jak2,Bcl2l11,Kdr,Pdgfrb,Pik3cd,Map2k1,Met |
| 4.051e-03 | -5.51 | GO_SIGNAL_TRANSDUCER_ACTIVITY | MSigDB lists | GO_SIGNAL_TRANSDUCER_ACTIVITY | 1495 | 147 | 15632 | 1249 |
Nfkbib,Ednrb,Ikbkg,Tnfrsf1b,Casp8,Notch2,Ptk2,Tlr9,Ptgir,Lpar1,Map2k4,Lyn,Stap1,S1pr2,Psd,Scarf1,Nr4a1,Spn,Syk,Itgav,Gpr18,Sdc4,Tspo,Cd80,Ahr,Fas,Nek6,Fpr2,Mul1,Nr1h3,Irs2,Gpr141,P2ry14,Gpr132,Nrp2,H2-Aa,Rapgef2,Il12rb1,Fzd1,Ccr1,Gja1,Flrt2,Fzd5,Map2k1,Pdgfrb,Ikbke,Htr2b,Sp110,Crkl,Tlr3,Gng4,Ripk2,Hmox1,Adora2b,Nr4a3,Gpr85,Map3k8,Il2rg,Stat3,Sele,Gpr68,Stat5a,Traf2,P2ry13,Csf3r,Gnb4,Cd14,Cd74,Cysltr2,Ccrl2,Cd69,Met,Marco,Itgal,Gna15,Ptch1,Ogfr,P2ry2,Kdr,Igf1r,Xcr1,Ebi3,Il13ra1,Stat1,Acvr1b,Tlr2,Adrb2,Ccr3,Prokr1,Igsf6,Prkce,Gpr35,Flt1,Map3k6,Cx3cr1,Flrt3,Htr2a,Gng11,Fcgr1,Tnfrsf14,Tlr6,Mapkapk2,Lrp8,Trim13,Il4ra,Antxr1,Tlr1,Olfr56,Adora2a,Map4k4,Plk2,Cd86,Plcl2,Cmklr1,Gng12,Il15ra,Plaur,Hcar2,H2-Ab1,Ptger4,Il12b,Nsmaf,Ptafr,Fpr1,Nr3c1,Gpr84,Acvr1,Acvrl1,Axl,Ifnar1,Itpr1,P2ry12,Rgs14,Cd40,Tnfrsf8,Daxx,Crim1,Ripk3,Rhoc,Malt1,Itga4,Icam1,Stat2,Calcrl,Agtrap,Trim12c,Sphk1 |
| 4.054e-03 | -5.51 | MODULE_175 | MSigDB lists | MODULE_175 | 48 | 10 | 15632 | 1249 |
Phlda1,Igf1r,Il15ra,Aoah,Ccr1,Col18a1,Sp140,Cx3cl1,Plod2,Trip10 |
| 4.054e-03 | -5.51 | GO_POSITIVE_REGULATION_OF_REPRODUCTIVE_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_REPRODUCTIVE_PROCESS | 48 | 10 | 15632 | 1249 |
Inhba,Pde5a,Plau,Acvr1b,Ptafr,P2ry2,Cited2,Prdm9,Ptger4,Ednrb |
| 4.054e-03 | -5.51 | ONDER_CDH1_TARGETS_3_DN | MSigDB lists | ONDER_CDH1_TARGETS_3_DN | 48 | 10 | 15632 | 1249 |
Dusp6,Ptgs2,Lcn2,P2ry2,Cxcl1,Edn1,Serpinb2,Csf3,Cxcl2,Il1b |
| 4.054e-03 | -5.51 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | MSigDB lists | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | 48 | 10 | 15632 | 1249 |
Psmb10,Odc1,Psmb9,Psmd10,Psmb6,Psmb8,Psme1,Psma6,Nqo1,Psme2 |
| 4.054e-03 | -5.51 | GTAAACC_MIR2995P | MSigDB lists | GTAAACC_MIR2995P | 48 | 10 | 15632 | 1249 |
H3f3b,Mecp2,Hspa2,Rsbn1,Rap2c,Ppp2r5a,Tiparp,Map3k8,Mafg,Abr |
| 4.082e-03 | -5.50 | positive regulation of collagen biosynthetic process | biological process | GO:0032967 | 31 | 7 | 20694 | 1406 |
Prdx5,Pdgfrb,Ccl2,Rgcc,Il18,Serpine1,Pdgfb |
| 4.082e-03 | -5.50 | establishment of endothelial barrier | biological process | GO:0061028 | 31 | 7 | 20694 | 1406 |
Rapgef2,Ezr,F11r,Myadm,Rap2c,Myd88,Icam1 |
| 4.082e-03 | -5.50 | immunoglobulin production involved in immunoglobulin mediated immune response | biological process | GO:0002381 | 31 | 7 | 20694 | 1406 |
Pou2f2,Fgl2,Batf,Icosl,Swap70,H2-Ab1,Nod2 |
| 4.082e-03 | -5.50 | regulation of peptidyl-serine phosphorylation of STAT protein | biological process | GO:0033139 | 31 | 7 | 20694 | 1406 |
Ifna4,Ifnb1,Ifna2,Ifna5,Ifna1,Lif,Ifna6 |
| 4.082e-03 | -5.50 | regulation of nitric-oxide synthase activity | biological process | GO:0050999 | 31 | 7 | 20694 | 1406 |
Arg2,Htr2b,Atp2b4,Gch1,Il1b,Nod1,Cav1 |
| 4.094e-03 | -5.50 | thymus development | biological process | GO:0048538 | 56 | 10 | 20694 | 1406 |
Lmo4,Ikzf1,Bcl2l11,Atm,Cited2,Crkl,Pbx1,Ripk3,Map2k1,Jarid2 |
| 4.095e-03 | -5.50 | polyubiquitin modification-dependent protein binding | molecular function | GO:0031593 | 55 | 10 | 20217 | 1400 |
Ikbkg,Tnip3,Dnajb2,Tnfaip3,Parp10,Tnip1,Ikbke,Sqstm1,Tab2,Optn |
| 4.100e-03 | -5.50 | Autodegradation of the E3 ubiquitin ligase COP1 | REACTOME pathways | R-MMU-349425 | 51 | 11 | 8608 | 757 |
Psmb10,Cop1,Psmb8,Psmb9,Atm,Psme1,Psmd10,Psme2b,Psme2,Psmb6,Psma6 |
| 4.100e-03 | -5.50 | Regulation of ornithine decarboxylase (ODC) | REACTOME pathways | R-MMU-350562 | 51 | 11 | 8608 | 757 |
Psmb8,Psmb9,Odc1,Nqo1,Psmb10,Psma6,Psme2,Psmb6,Psme2b,Psme1,Psmd10 |
| 4.103e-03 | -5.50 | regulation of synapse structure or activity | biological process | GO:0050803 | 276 | 31 | 20694 | 1406 |
Etv5,Fcgr2b,Adgrl2,Il10,Sema4a,Prnp,Nrp2,Tnf,Lrp4,Fzd1,Mecp2,Cyfip1,Agrn,Chmp4b,Ptk2,Arf4,Srgn,Lrp8,Cdk5r1,Tlr2,Igsf9,Slc7a11,Flrt2,Ntng2,Sipa1l1,Flrt3,Rims3,Homer1,Dbnl,Nlgn2,Crkl |
| 4.118e-03 | -5.49 | MARCKS | prints domains | PR00963 | 2 | 2 | 5821 | 374 |
Marcks,Marcksl1 |
| 4.118e-03 | -5.49 | IL6GCSFMGF | prints domains | PR00433 | 2 | 2 | 5821 | 374 |
Il6,Csf3 |
| 4.118e-03 | -5.49 | HIGHMOBLTYIY | prints domains | PR00930 | 2 | 2 | 5821 | 374 |
Hmga2,Hmga1 |
| 4.120e-03 | -5.49 | regulation of cell migration involved in sprouting angiogenesis | biological process | GO:0090049 | 39 | 8 | 20694 | 1406 |
Ptgs2,Hmox1,Notch1,Akt3,Kdr,Plk2,Thbs1,Spred1 |
| 4.120e-03 | -5.49 | positive regulation of cardiac muscle hypertrophy | biological process | GO:0010613 | 39 | 8 | 20694 | 1406 |
Sirt1,Edn1,Nr3c1,Slc9a1,Pde5a,Nr4a3,Ptk2,Trip10 |
| 4.120e-03 | -5.49 | negative regulation of response to drug | biological process | GO:2001024 | 39 | 8 | 20694 | 1406 |
Il10,Tnf,Txn1,Glrx,Nr4a3,Hsph1,Met,Hk3 |
| 4.152e-03 | -5.48 | MODULE_157 | MSigDB lists | MODULE_157 | 97 | 16 | 15632 | 1249 |
Stxbp1,Lif,Gng4,Il2rg,Fgr,Sla,Pfkfb3,Cd34,Rapgef5,Ccl12,Flt1,Gna15,Oas2,Smpdl3b,Psd,Stat4 |
| 4.176e-03 | -5.48 | TF_DNA-bd_sf | interpro domains | IPR008917 | 16 | 5 | 19984 | 1430 |
Junb,Jun,Mafg,Maff,Mafk |
| 4.176e-03 | -5.48 | Pro_4_hyd_alph | interpro domains | IPR006620 | 16 | 5 | 19984 | 1430 |
Plod3,Egln3,Plod2,P4ha2,P4ha1 |
| 4.190e-03 | -5.47 | GSE41978_WT_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41978_WT_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | 188 | 26 | 15632 | 1249 |
Spint2,Cxcl2,Slc12a9,Clec4n,Fzd5,Slc7a2,Dr1,Serpinb2,Plekhn1,Il1b,Dram1,Fam53c,Sema4a,Lyn,Gpr35,Prkce,Pdpn,Axl,Trip10,Cd34,Sgcb,Clec4e,Fcgr1,Notch1,Hck,Fpr2 |
| 4.190e-03 | -5.47 | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_DN | MSigDB lists | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_DN | 188 | 26 | 15632 | 1249 |
Serpine1,Vps54,Lmo4,G3bp2,Kctd12,Mtdh,Tmod3,Ell2,Dck,Plaur,Esd,Frmd6,Nfil3,Acpp,Eif2ak2,Slc7a11,Abcc5,Gsr,Psma6,Nr3c1,Ccr3,Fut8,Irgm2,Nat2,Usp18,Tnfaip3 |
| 4.190e-03 | -5.47 | GSE40443_INDUCED_VS_TOTAL_TREG_UP | MSigDB lists | GSE40443_INDUCED_VS_TOTAL_TREG_UP | 188 | 26 | 15632 | 1249 |
Trib1,Nr4a3,Gpd2,Mmp9,Slc39a14,Hivep3,Itgal,Lmo4,Plod2,Jarid2,Etv5,Relb,Samhd1,Rbms2,Icam1,Egr1,Bcor,Kdm5b,Stk40,Irgq,Egr2,Klhl25,Nr4a1,Armcx6,Ppp6r1,Bcl2l11 |
| 4.213e-03 | -5.47 | HEXOKINASE_1 | prosite domains | PS00378 | 5 | 3 | 13278 | 1037 |
Hk1,Hk3,Hk2 |
| 4.213e-03 | -5.47 | INTERLEUKIN_1 | prosite domains | PS00253 | 5 | 3 | 13278 | 1037 |
Il1a,Il1b,Il1rn |
| 4.213e-03 | -5.47 | HEXOKINASE_2 | prosite domains | PS51748 | 5 | 3 | 13278 | 1037 |
Hk3,Hk1,Hk2 |
| 4.216e-03 | -5.47 | regulation of supramolecular fiber organization | biological process | GO:1902903 | 346 | 37 | 20694 | 1406 |
Swap70,Rhoc,Rac3,Gda,Edn1,Asap3,Dbnl,Myadm,Rgcc,Icam1,Tlr2,Prkce,Spire1,Tmsb10,Carmil1,Cav1,Rictor,Whamm,Plek,Csf3,Cdc42ep4,Met,Cdc42ep2,Nck1,Evl,Ldlr,Hcls1,Sdc4,Mecp2,Cyfip1,Ptger4,Cx3cl1,Mid1,Tmod3,Vasp,Fchsd2,Lpar1 |
| 4.224e-03 | -5.47 | muscle organ development | biological process | GO:0007517 | 288 | 32 | 20694 | 1406 |
Cav1,Nupr1,Maff,Egr1,Flnb,Homer1,Cd164,Rcan1,Notch1,Hivep3,Btg2,Sgcb,Myc,Arid5b,Sirt1,Bcl9,Hlx,Fos,Fzd1,Cflar,Sap30,Psma6,Plagl1,Cited2,Lif,Egr2,Atf3,Nr4a1,Bmp2,Angpt1,Serp1,Met |
| 4.224e-03 | -5.47 | LIU_PROSTATE_CANCER_DN | MSigDB lists | LIU_PROSTATE_CANCER_DN | 428 | 50 | 15632 | 1249 |
Traf5,Pdgfc,Crim1,Gbp2,Klf8,Slco3a1,Tbc1d1,Fchsd2,Rbpms,C1ra,Casp1,Gypc,Dse,Tpst1,Pcdh7,Inpp1,Kitl,Clic4,Phlda1,Eya4,Slc25a12,Uba7,Csrp1,Gja1,Tuba4a,Col4a2,Plau,Atp2b4,Palld,Sdc1,Plagl1,Ccnd2,Cx3cl1,Optn,Tmem200b,Tagln,Flrt3,Ets2,Rbms1,Col27a1,H3f3b,Frmd6,Lpar1,Itga9,Ksr1,Met,Eno2,Cav1,Plekha2,Layn |
| 4.232e-03 | -5.47 | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_UP | 160 | 23 | 15632 | 1249 |
Zcchc2,Nfil3,Ap3m2,Cd200,Spint2,Slamf9,Jag1,Hivep3,Mthfd1l,Slc16a1,Ube2f,Extl2,Vcpip1,Hk3,Clcn5,Tpi1,Ch25h,Calcrl,Ccnd2,Ccl22,Myc,Ccl2,Spn |
| 4.232e-03 | -5.47 | GO_NEGATIVE_REGULATION_OF_CELL_GROWTH | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_GROWTH | 160 | 23 | 15632 | 1249 |
Sh3bp4,Inhba,Sirt1,Sema3c,Gja1,Dcun1d3,Dcbld2,Cdkn1a,Acvr1b,Sema4a,Ptprj,Sema4c,Gng4,Ifrd1,Acvrl1,Eno1,Bcl6,Crlf3,Sertad3,Mul1,Cdk5r1,Cdkn2d,Pml |
| 4.232e-03 | -5.47 | YAMAZAKI_TCEB3_TARGETS_UP | MSigDB lists | YAMAZAKI_TCEB3_TARGETS_UP | 160 | 23 | 15632 | 1249 |
Wars,Pde1b,Ext1,Sat1,Fut8,Cited2,Plod2,Zyx,P4ha1,Flrt3,Nr4a1,P4ha2,Mdfic,Cd38,Plat,Slc16a1,Col4a2,Arf4,Grina,Ccnd2,Rcn1,Dyrk2,Fndc3a |
| 4.232e-03 | -5.47 | GSE3982_BCELL_VS_TH2_UP | MSigDB lists | GSE3982_BCELL_VS_TH2_UP | 160 | 23 | 15632 | 1249 |
Ppfibp2,Prkar2b,Stoml1,Tbc1d13,Rabgef1,Ifit1bl2,Irf8,Golga3,Casp4,Zbtb5,Zbp1,Psme1,Arl4a,Il6,Fchsd2,Slc15a3,Dusp1,Ifit1bl1,Tagln,Plekhf2,Rapgef5,N4bp1,Tspan3 |
| 4.236e-03 | -5.46 | regulation of heart growth | biological process | GO:0060420 | 84 | 13 | 20694 | 1406 |
Sirt1,Nr3c1,Tomm70a,Notch1,Sav1,Jarid2,Trip10,Dusp6,Edn1,Gja1,Cited2,Ahr,Pim1 |
| 4.243e-03 | -5.46 | dioxygenase activity | molecular function | GO:0051213 | 92 | 14 | 20217 | 1400 |
Riox2,Rsbn1,Kdm4a,Egln3,Ptgs2,Phyh,P4ha2,P4ha1,Jmjd6,Kdm6b,Tet2,Plod2,Kdm5b,Plod3 |
| 4.253e-03 | -5.46 | GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 72 | 13 | 15632 | 1249 |
Itgav,Ccl12,Axl,Src,Flt1,Cyfip1,Nrp2,Mapkapk2,Nck1,Ptk2,Kdr,Actb,Vegfc |
| 4.255e-03 | -5.46 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP | 56 | 11 | 15632 | 1249 |
Nupr1,Gja1,Tgfbi,Upp1,Fut8,Casp3,Kitl,Gpc1,Tspo,Ccnd1,Cdkn1a |
| 4.255e-03 | -5.46 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | MSigDB lists | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | 56 | 11 | 15632 | 1249 |
Vcam1,Cd34,Icam1,Sell,H2-Q7,C3,Fcgr2b,Itgal,H2-Q6,Cd40,H2-Q4 |
| 4.281e-03 | -5.45 | GAB1 signalosome | REACTOME pathways | R-MMU-180292 | 113 | 19 | 8608 | 757 |
Pik3cd,Pdgfrb,Ppp2r1b,Cd86,Nr4a1,Kitl,Cdkn1a,Pdgfb,Met,Mdm2,Ier3,Rictor,Phlpp1,Src,Irs2,Ppp2r5a,Trib3,Phlpp2,Cd80 |
| 4.281e-03 | -5.45 | PI3K/AKT activation | REACTOME pathways | R-MMU-198203 | 113 | 19 | 8608 | 757 |
Phlpp1,Rictor,Trib3,Ppp2r5a,Irs2,Phlpp2,Cd80,Src,Cdkn1a,Kitl,Ier3,Mdm2,Met,Pdgfb,Cd86,Ppp2r1b,Nr4a1,Pik3cd,Pdgfrb |
| 4.293e-03 | -5.45 | LINDGREN_BLADDER_CANCER_CLUSTER_1_UP | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_1_UP | 106 | 17 | 15632 | 1249 |
Mob3c,Ifi207,Igf1r,Esd,Snapc1,Ifi204,Ifi214,Zfp513,Ifi203,Ifi211,Ifi208,Bbx,Ifi205,Ifi209,Mndal,Ifi213,Casp1 |
| 4.307e-03 | -5.45 | GO_CELLULAR_RESPONSE_TO_DRUG | MSigDB lists | GO_CELLULAR_RESPONSE_TO_DRUG | 64 | 12 | 15632 | 1249 |
Ppp1r15a,Nos2,Pde4b,Ccl12,Cd69,Edn1,Myc,Prnp,Hif1a,Tlr3,Aim2,Il1b |
| 4.307e-03 | -5.45 | KEGG_RENAL_CELL_CARCINOMA | MSigDB lists | KEGG_RENAL_CELL_CARCINOMA | 64 | 12 | 15632 | 1249 |
Pik3cd,Slc2a1,Jun,Map2k1,Hif1a,Pik3r5,Crkl,Met,Egln3,Vegfc,Akt3,Pdgfb |
| 4.329e-03 | -5.44 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN | 179 | 25 | 15632 | 1249 |
Aff1,Traf1,Socs1,Irs2,Atf3,Prokr1,Lrch1,Otud1,Arid5a,Parp8,Plekhf2,Tagap,Pkp4,Rcl1,Wdr43,Pim1,Adrb2,Clec4d,St3gal1,Ripk2,Zscan29,Rnf19a,Fosb,Casp4,Pde4b |
| 4.329e-03 | -5.44 | GSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN | 179 | 25 | 15632 | 1249 |
Sesn3,Ikbkg,Lnpep,Btg2,Kctd12,Itpkc,Dusp5,Rcsd1,Mafg,Azi2,Adrb2,Phf6,Adam19,Dnajb2,Hivep2,Egr2,Rhoq,Nr3c1,Cept1,Ifrd1,Kdm5b,Pikfyve,Nxf1,Spata13,Klf7 |
| 4.329e-03 | -5.44 | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_DN | 179 | 25 | 15632 | 1249 |
Nqo1,Cxcl14,Tapbp,Rin2,Egr2,Mdn1,Tcf4,Slc7a11,Eif2ak2,Ahr,Hinfp,Slc30a1,Ifih1,Il1a,Nkiras1,Kctd12,Ccrl2,Csf1,Ddit4,Dusp6,Igf1r,Vcam1,Znrf1,Acsl1,Ptprj |
| 4.329e-03 | -5.44 | GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN | 179 | 25 | 15632 | 1249 |
Slfn8,Ikzf1,Cish,Slc15a3,Rhoq,Phactr4,Cers6,Hsph1,Itpr1,Tcf4,Pde3b,Notch1,Sphk1,Cnn3,Jdp2,Irf8,Cnp,Plekha2,Slc29a3,Slfn9,Hsd17b7,Hmgcs1,Dyrk2,Traf3ip2,Usp42 |
| 4.329e-03 | -5.44 | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_UP | 179 | 25 | 15632 | 1249 |
Nfkbid,Trim56,Wdr59,Ampd3,Tlr1,Slfn4,Ifit3,Card6,Slfn3,Tnip1,Slc25a22,Ifit3b,Nr4a3,Socs3,Treml2,Kdm5b,Dock10,Nr3c1,Arid5a,D16Ertd472e,Usp53,Agrn,Ccnd2,Pigv,Fas |
| 4.329e-03 | -5.44 | GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | MSigDB lists | GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | 179 | 25 | 15632 | 1249 |
P4ha1,Brd2,4930523C07Rik,Gbp7,Rnaset2a,Mmp14,Slfn8,Gadd45g,Oas2,Kctd12,Kdm5b,Treml2,Dyrk2,Rab20,Tgfbi,Usp18,Etv3,Ccnd2,Zfp281,Slfn9,Chd9,Pde3b,Sgk3,Rnaset2b,Crim1 |
| 4.329e-03 | -5.44 | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_DN | 179 | 25 | 15632 | 1249 |
Kif3c,Clec4d,Mefv,St7,Mob3b,Acp2,Dnajb2,Stip1,Pfkl,Gja1,Hsd17b12,Pdgfrb,Lad1,Btg2,Maff,Pou2f2,Pgs1,Ier2,Zfp281,Hck,Clcn5,Srm,Dusp2,Pcx,Stk40 |
| 4.329e-03 | -5.44 | GSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_UP | MSigDB lists | GSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_UP | 179 | 25 | 15632 | 1249 |
Phyh,Acsl1,Dck,Pf4,Il1rn,Chd9,Atp6v1d,Slc4a7,Ccl5,Psd4,Slc39a14,Spint2,Piezo1,Upp1,Slc30a1,Socs1,Egr1,Stxbp1,Ciita,Slc16a1,Tspan3,Gpsm2,Aoah,Bcl2l11,Ccng2 |
| 4.329e-03 | -5.44 | GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_UP | MSigDB lists | GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_UP | 179 | 25 | 15632 | 1249 |
Rhoc,Zbtb5,Dmxl2,Rars,Triobp,Mid1,Gpr68,Scarf1,Pnp2,Ifit1bl1,Nr4a1,Inpp1,Gca,Cxcl1,Dusp5,Il13ra1,Hp,Smox,Cxcl2,Smpdl3b,Rtn2,Ddit4,Tnfsf14,Tnfrsf1b,Ifit1bl2 |
| 4.360e-03 | -5.44 | NAKAJIMA_MAST_CELL | MSigDB lists | NAKAJIMA_MAST_CELL | 41 | 9 | 15632 | 1249 |
Dusp14,Plat,Alas1,Prdx1,Hdc,Timp1,Gdf15,Ccl12,Eno2 |
| 4.360e-03 | -5.44 | ZHAN_MULTIPLE_MYELOMA_LB_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_LB_UP | 41 | 9 | 15632 | 1249 |
Flnb,Edn1,Cflar,Rasgrp1,Usp53,Pcgf5,Nampt,Arid5b,Cacnb3 |
| 4.360e-03 | -5.44 | GO_REGULATION_OF_LEUKOCYTE_DEGRANULATION | MSigDB lists | GO_REGULATION_OF_LEUKOCYTE_DEGRANULATION | 41 | 9 | 15632 | 1249 |
Abr,Rabgef1,Hmox1,Syk,Adora2b,Lyn,Il4ra,Ptafr,Fgr |
| 4.360e-03 | -5.44 | GO_T_TUBULE | MSigDB lists | GO_T_TUBULE | 41 | 9 | 15632 | 1249 |
Slc30a1,Cacnb3,Ezr,Atp2b4,Rtn2,Scn1b,Cacna1d,Slc9a1,Kcnj2 |
| 4.371e-03 | -5.43 | erythrocyte differentiation | biological process | GO:0030218 | 94 | 14 | 20694 | 1406 |
Bcl6,Ptpn2,Ikzf1,Hcls1,Cited2,Klf2,Tcea1,Jak2,Casp3,Arid4a,Lyn,Jmjd6,Adar,Tmod3 |
| 4.372e-03 | -5.43 | TP53 Regulates Transcription of Cell Cycle Genes | REACTOME pathways | R-MMU-6791312 | 31 | 8 | 8608 | 757 |
Btg2,Plk3,Cdkn1a,Plk2,Ccne1,Cenpj,Cnot4,Tnks1bp1 |
| 4.375e-03 | -5.43 | REACTOME_GLYCOLYSIS | MSigDB lists | REACTOME_GLYCOLYSIS | 27 | 7 | 15632 | 1249 |
Pfkfb3,Ppp2r1b,Pfkl,Pgk1,Eno2,Tpi1,Eno1 |
| 4.375e-03 | -5.43 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 27 | 7 | 15632 | 1249 |
Apaf1,Casp4,Traf2,Ppp1r15a,Trib3,Itpr1,Pml |
| 4.375e-03 | -5.43 | BIOCARTA_GSK3_PATHWAY | MSigDB lists | BIOCARTA_GSK3_PATHWAY | 27 | 7 | 15632 | 1249 |
Eif2ak2,Nfkb1,Gja1,Ccnd1,Fzd1,Myd88,Cd14 |
| 4.375e-03 | -5.43 | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | MSigDB lists | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | 27 | 7 | 15632 | 1249 |
Rictor,Mdm2,Phlpp1,Cdkn1a,Akt3,Trib3,Nr4a1 |
| 4.375e-03 | -5.43 | MARSHALL_VIRAL_INFECTION_RESPONSE_DN | MSigDB lists | MARSHALL_VIRAL_INFECTION_RESPONSE_DN | 27 | 7 | 15632 | 1249 |
Nfkbib,Relb,Il18rap,Klf3,Nfkbia,Pim1,Klf2 |
| 4.376e-03 | -5.43 | GSE45365_WT_VS_IFNAR_KO_CD11B_DC_DN | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_CD11B_DC_DN | 142 | 21 | 15632 | 1249 |
Usp35,Rhou,Tor1aip2,Arl5b,B4galt4,Nlrc4,Tiparp,Dach1,Rab32,Cenpe,Hk3,Vrk2,Gsta3,Myo10,Armc8,Siglece,Nkiras1,Xrn1,Agtrap,Dram1,Hp |
| 4.376e-03 | -5.43 | SMITH_TERT_TARGETS_UP | MSigDB lists | SMITH_TERT_TARGETS_UP | 142 | 21 | 15632 | 1249 |
Cd55,Atf3,Mthfd2,Ptgs2,Bmp2,Dr1,Gfpt1,Cxcl1,Tcea1,Ppp2r2a,Ahr,Nfil3,Nfkb1,Dusp1,Lmo4,Asns,Zfp36,Tnc,Cebpd,Etv6,Ifrd1 |
| 4.379e-03 | -5.43 | GO_DOUBLE_STRANDED_DNA_BINDING | MSigDB lists | GO_DOUBLE_STRANDED_DNA_BINDING | 662 | 72 | 15632 | 1249 |
Irf4,Myc,Fos,Jun,Ets2,Hmga1,Nlrc5,Ifi207,Hinfp,Kat2b,Plagl1,Etv3,Ifi214,Ddx60,Atf3,Egr1,Sirt1,Stat4,Pou2f2,Etv6,Ifi203,Ifi211,Rel,Mndal,Lmo4,Nfkb1,Jdp2,H3f3b,Nfil3,Actb,Rbms1,Ifi204,Irf1,Max,Stat1,Hdac1,Aebp2,Mecp2,Mafk,Cebpd,Nr3c1,Stat3,Egr2,Batf2,Bcl6,Ifi209,Tcf4,Ifi205,Klf6,Ifi213,Etv5,Relb,Batf,Pbx1,Tal2,Zfp281,Ddx58,Prdm1,Hhex,Aim2,Mcm10,Irf2,Mxd1,Ifi208,Fosb,Irf7,Junb,Jarid2,Nfxl1,Nfkb2,Arid5b,Nr4a3 |
| 4.381e-03 | -5.43 | ACEVEDO_LIVER_CANCER_DN | MSigDB lists | ACEVEDO_LIVER_CANCER_DN | 481 | 55 | 15632 | 1249 |
Fosb,Serpine1,Ppp1r15a,Klf2,Rgl1,Phlda1,Slc7a5,Trib3,Ldha,Dusp5,Ppp2r2a,Acp2,Rcl1,Eno1,Ifnar1,Dync1h1,Cers6,Ccnd1,Oaf,Phgdh,Psmb10,Kmo,Csrnp1,Myo10,C1rl,Irf8,Tnfrsf1b,Dcun1d3,Tor3a,Slc39a14,Zfp36,Ier3,Irf1,Rcn1,Trib1,C3,Hmgcs1,Ppfibp2,H3f3b,Ldlr,Sh3bgrl2,Dnaja1,Ets2,Fos,Ezr,Nfkbia,I830077J02Rik,Prnp,Pgm1,Egr1,Nek6,Evl,Tnfrsf14,Rnd3,Sdc4 |
| 4.384e-03 | -5.43 | GO_ENDOPLASMIC_RETICULUM | MSigDB lists | GO_ENDOPLASMIC_RETICULUM | 1464 | 144 | 15632 | 1249 |
Vcpip1,Tap1,Rras2,Pde3b,Trim13,Prnp,Tmtc2,Nlrp3,Ppm1l,Pgs1,Edn1,Kcnj2,Prkce,Fos,H2-Q4,Slc7a11,Flrt3,Ccl12,Rnaset2b,Esd,Agpat4,Tmem67,Kdr,Rcn1,Acsl1,Oas1a,Slc39a14,Rasgrp1,Ksr1,Casp4,P4ha1,Notch1,Bfar,Ahsa1,Calcrl,Agtrap,H2-Q7,Pml,Tapbp,Atp13a1,Minpp1,Rab9,Dse,Itpr1,Plekhf2,Slc37a3,Plaur,Il15ra,Sec24b,Osbpl3,Acsl5,Thbs1,Ptgs2,Grina,Tapbpl,Shisa3,H2-Ab1,Oas1g,Uchl1,Zc3h12a,Hap1,Oas2,Caml,Pdgfb,Rnaset2a,Snx10,Atp11b,Col4a2,Extl2,F10,Lpcat2,Slc30a1,Nck1,Col18a1,Usp25,Cept1,Bnip3,Tor1aip2,Ctsc,Pla2g4a,Dnaja1,Ptpn2,Dhrs9,Ass1,Sqstm1,Lrrc8c,Hsd17b7,Vrk2,Notch2,Col27a1,Mppe1,Cpeb4,Mtdh,Tlr9,Itga5,Syne2,Slc9a1,Rtn2,Cav1,Plod2,Tor3a,Pdgfc,Stau1,1600014C10Rik,Cd74,Atp11a,Pigv,Ch25h,Rnf139,Rsad2,Cers6,Rab21,Traf2,H2-Q6,Serp1,P2ry13,Rhbdf2,P4ha2,Ifit2,Plod3,Keap1,Ptges,Vcam1,Sec24a,Gpr85,Tlr3,Atp10a,Hmox1,Rtn1,Degs2,Rab10,Ext1,H2-Aa,Piezo1,Ppp1r15a,Tap2,Col11a2,Flrt2,Rrs1,Map2k1,Ttc9c,H2-Eb1,Hsd17b12,Gja1 |
| 4.405e-03 | -5.43 | MODULE_174 | MSigDB lists | MODULE_174 | 89 | 15 | 15632 | 1249 |
Piezo1,Dusp2,Tlr1,Cp,Ccr1,Aoah,Sod2,Gdf15,Gna15,Csf3r,Mgat1,Trip10,Cd14,Hlx,Ier3 |
| 4.405e-03 | -5.43 | CAHOY_ASTROGLIAL | MSigDB lists | CAHOY_ASTROGLIAL | 89 | 15 | 15632 | 1249 |
Tspo,Fas,Hmox1,C3,Traf1,Lox,Cp,Glipr2,Ltbp2,Tagln,Casp1,Insl6,Timp1,Lcn2,Serpine1 |
| 4.413e-03 | -5.42 | regulation of neuron projection development | biological process | GO:0010975 | 601 | 58 | 20694 | 1406 |
Mdm2,Sirt1,Gfi1,Il15ra,Scarf1,Crkl,Sphk1,Dbnl,Rap1gap2,Itpr1,Kremen1,Lyn,Cdk5r1,Nr3c1,Rapgef2,Plk2,Map4k4,Cd38,Sema3c,Sema4a,Hap1,Map2k1,Eif4g2,Lif,Cyfip1,Scn1b,Il6,Cflar,Mul1,Lpar1,Lrp4,Mark2,Ptk2,Dync1i2,Prag1,Agrn,Ifrd1,Igf1r,Nlgn2,D16Ertd472e,Sema4c,Sipa1l1,Kat2b,Lrp8,Ust,Nck1,Met,Rab21,Sdc2,Katna1,Mov10,Mecp2,Kif3c,Ehd1,Fzd1,P2ry2,Zswim4,Cx3cl1 |
| 4.429e-03 | -5.42 | CTTTGT_LEF1_Q2 | MSigDB lists | CTTTGT_LEF1_Q2 | 1751 | 169 | 15632 | 1249 |
Map4k4,Sesn3,Gch1,Ccnj,Ppm1k,Plk2,Cnp,Slc2a6,Btg2,Stx11,Dgka,Smc5,Uchl1,Ptprj,Smox,Lox,Kif3c,Pim1,Tnfsf10,Zhx2,Glrx,Dio2,Ehd1,Hsph1,Dync1h1,Dusp1,Parp8,P2ry12,Rhoq,Fchsd2,Fut8,Stk40,Ccnd1,Myo10,Clcn5,Notch1,Crim1,Dach1,Eif4g2,P2ry2,Akt3,Bcl9,Met,Casp2,Il13ra1,Pik3cd,Adrb2,Slc25a22,Acvr1b,Fam20c,Tmem67,Actb,Prkar2b,Igf1r,Agpat4,Pik3r5,Bcl2l11,Flrt3,Slc7a11,Rab32,Dock4,Fos,Cyfip1,Tet2,Bbx,Il6,Slc44a1,Spry2,Ncoa5,Kremen1,Tra2a,Lrp8,Gbe1,Gng11,Rnd3,Pfkfb3,Angpt1,Gja1,Arl5b,Tmeff1,Rab10,Nrp2,Ddit4,Sap30,Fzd1,Ppp2r3a,Eya4,Vasn,Rtn1,Crkl,St7,Cdc42ep4,Gpr85,Nr4a3,Tmem229b,Gcnt2,Ralgds,Pcdh7,Gtpbp2,Snn,Abcc5,Txnrd1,Bcl6,Mtus1,Arid5a,Rnf24,Itgb8,Stat3,Ccng2,B3gnt5,Cers6,Tlk2,Rbpms,Glipr2,Pigv,Klf8,F11r,Cd74,Sgk3,Tsku,Olfml3,Rgs3,Pdgfc,Dcun1d3,Plod2,Lmo4,Rtn2,Cnn3,Kctd12,Etv6,Mmd,Sema4c,Hmgcs1,Egr3,Tnip3,Odc1,Dnajb4,Trib1,Rap2c,Ust,Adam19,Notch2,Rbms1,Nfil3,H3f3b,Dhrs9,Morc3,Klf3,Dnaja1,Hmga1,Cited2,Mmp14,Bnip3,Mid1,Dusp4,Mllt6,Rin2,S1pr2,Psd,Cnot4,Vcan,Arl4a,Cdk5r1,Sdc1,Slc16a1,Extl2,Tle3,Klf7,Foxp4 |
| 4.437e-03 | -5.42 | Irf7 (interferon regulatory factor 7) | protein interactions | 54123 | 8 | 4 | 7778 | 753 |
Gbp4,Nmi,Myd88,Rsad2 |
| 4.437e-03 | -5.42 | RPL18A (ribosomal protein L18a) | protein interactions | 6142 | 8 | 4 | 7778 | 753 |
Brwd3,Rrbp1,Ksr1,Ktn1 |
| 4.437e-03 | -5.42 | Optn (optineurin) | protein interactions | 71648 | 8 | 4 | 7778 | 753 |
Sema4a,Optn,Fos,Sqstm1 |
| 4.445e-03 | -5.42 | CREB_Q2 | MSigDB lists | CREB_Q2 | 237 | 31 | 15632 | 1249 |
Noc4l,Nfkbid,Jag1,Maff,Ppp1r15a,Gem,Fosb,Pkp4,Dnajb2,Egr3,Sema4c,Ldha,Slc31a1,Trib1,Rcan1,Nr4a3,Stat3,Nr3c1,Ift57,Slc25a37,Dusp1,Gadd45b,Fos,Rbbp8,Zmynd15,Rbms2,Relb,Tle3,Atf3,Hhex,Egr1 |
| 4.453e-03 | -5.41 | ARID | prosite domains | PS51011 | 15 | 5 | 13278 | 1037 |
Arid5a,Kdm5b,Arid4a,Arid5b,Jarid2 |
| 4.458e-03 | -5.41 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_DN | 170 | 24 | 15632 | 1249 |
Phlda1,Stx6,Dach1,Med21,Rrs1,Cacybp,Lcp2,Asns,Osbpl3,Mob3c,Cd200,Ggct,Irf4,Chst11,Srm,Ppp1r14b,Tnf,Rbbp8,Homer1,Dse,Prdx1,Gbp2,Dusp14,Prpf38a |
| 4.458e-03 | -5.41 | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP | 170 | 24 | 15632 | 1249 |
Atp11a,Socs1,Il4ra,P2ry14,Slc30a4,Klf7,Rhoc,Nod1,Fbxo4,Cd302,Tpst1,Treml2,Abcb1a,Slc39a4,Lrch1,Pde1b,Xkr8,Hmgcs1,Il13ra1,Cd200,Plk2,Tbc1d13,Cysltr2,Timeless |
| 4.458e-03 | -5.41 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_UP | 170 | 24 | 15632 | 1249 |
Txn1,Ttc9c,Gsdmd,Ppp1r15b,Ccl5,Eno1,Rhof,Alas1,Piezo1,Etv6,Spint2,Magohb,Mtmr14,Palld,Ccl22,Traf1,Slco3a1,Nfxl1,Sdc4,Cutc,Sla,Daxx,Ppfibp2,Pdgfc |
| 4.463e-03 | -5.41 | negative regulation of lipid storage | biological process | GO:0010888 | 17 | 5 | 20694 | 1406 |
Itgav,Ptpn2,Nr1h3,Ttc39b,Nfkbia |
| 4.463e-03 | -5.41 | histone mRNA metabolic process | biological process | GO:0008334 | 17 | 5 | 20694 | 1406 |
Dcp2,Atm,Tent4a,Tent2,Xrn1 |
| 4.463e-03 | -5.41 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment | biological process | GO:0043369 | 17 | 5 | 20694 | 1406 |
Irf4,Stat3,Batf,Il6,Spn |
| 4.463e-03 | -5.41 | positive regulation of transforming growth factor beta production | biological process | GO:0071636 | 17 | 5 | 20694 | 1406 |
Cd200,Cx3cl1,Ptgs2,Thbs1,Cd34 |
| 4.463e-03 | -5.41 | positive regulation of B cell differentiation | biological process | GO:0045579 | 17 | 5 | 20694 | 1406 |
Il2rg,Syk,Stat5a,Prdm1,Mmp14 |
| 4.463e-03 | -5.41 | positive regulation of humoral immune response | biological process | GO:0002922 | 17 | 5 | 20694 | 1406 |
Nod2,C3,Acod1,Il1b,Tnf |
| 4.463e-03 | -5.41 | positive regulation of autophagy of mitochondrion | biological process | GO:1903599 | 17 | 5 | 20694 | 1406 |
Hif1a,Hk2,Bnip3,Mul1,Optn |
| 4.469e-03 | -5.41 | regulation of response to endoplasmic reticulum stress | biological process | GO:1905897 | 75 | 12 | 20694 | 1406 |
Tmem67,Ikbkg,Usp25,Nupr1,Sirt1,Ppp1r15a,Ptpn2,Nck1,Bfar,Fcgr2b,Ppp1r15b,Grina |
| 4.500e-03 | -5.40 | GSE339_CD8POS_VS_CD4CD8DN_DC_UP | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_UP | 189 | 26 | 15632 | 1249 |
Mdn1,Pde1b,Gsr,Flt1,Sqstm1,Gys1,Pbx1,Tap1,Prpf38a,Nek6,Col18a1,Procr,Plscr1,Gdf15,Irf8,Lap3,Adam19,Ppfibp2,Glrx,Xcr1,Odc1,Cxcl10,Kif3c,Sema4a,Il18,Serpinb9 |
| 4.500e-03 | -5.40 | GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 189 | 26 | 15632 | 1249 |
Calcrl,Rtp4,Usp25,Daxx,Ripk3,Slc28a2,Ciita,Otud1,Parp8,Syk,Arhgap26,Errfi1,Mllt6,Ms4a6d,Aida,Nr4a3,Map3k8,Ptger4,Parp3,Epsti1,Sec24b,Hopx,Cd86,Plekha2,Gch1,Stx6 |
| 4.500e-03 | -5.40 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | 189 | 26 | 15632 | 1249 |
Heatr6,Rel,Atxn7l1,Tmeff1,Car13,Oas1a,Vasn,Oas1g,Osgin2,Jak2,Hsd17b7,Itgav,Ppp6r1,Gypc,Ifit2,Rhof,Itpr1,Dennd1b,Dtnb,Cdkn2d,Magohb,Il4ra,Phip,Hif1a,Trp53i11,Herc3 |
| 4.500e-03 | -5.40 | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_UP | MSigDB lists | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_UP | 189 | 26 | 15632 | 1249 |
H2-Q4,Klf6,Pik3r5,Otud1,H2-Q6,D16Ertd472e,Birc2,Abcb1a,Gpr68,H2-Q7,Zfp281,St3gal6,Crim1,4930523C07Rik,Card6,Pid1,Heatr6,Trim56,Filip1l,Rac3,Kif5c,Dyrk2,Acvr1b,Cflar,Ldlr,Dnajb2 |
| 4.500e-03 | -5.40 | JU_AGING_TERC_TARGETS_DN | MSigDB lists | JU_AGING_TERC_TARGETS_DN | 5 | 3 | 15632 | 1249 |
Pf4,Kitl,Ccl5 |
| 4.500e-03 | -5.40 | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_DN | MSigDB lists | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_DN | 5 | 3 | 15632 | 1249 |
Cd34,Olr1,Sele |
| 4.500e-03 | -5.40 | FERRARI_RESPONSE_TO_FENRETINIDE_DN | MSigDB lists | FERRARI_RESPONSE_TO_FENRETINIDE_DN | 5 | 3 | 15632 | 1249 |
Ldlr,Cd34,Hspa2 |
| 4.500e-03 | -5.40 | LIU_IL13_MEMORY_MODEL_DN | MSigDB lists | LIU_IL13_MEMORY_MODEL_DN | 5 | 3 | 15632 | 1249 |
Il13ra1,Bcl2l11,Dusp4 |
| 4.507e-03 | -5.40 | Hypertrophy Model | WikiPathways | WP202 | 20 | 7 | 4813 | 540 |
Il18,Dusp14,Zeb1,Atf3,Il1a,Nr4a3,Ifrd1 |
| 4.511e-03 | -5.40 | JEPSEN_SMRT_TARGETS | MSigDB lists | JEPSEN_SMRT_TARGETS | 34 | 8 | 15632 | 1249 |
Esd,Srxn1,Zbtb5,Timp1,Hmga1,Kdm6b,Hmox1,Egr1 |
| 4.511e-03 | -5.40 | QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2 | MSigDB lists | QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2 | 34 | 8 | 15632 | 1249 |
Srm,Slc16a3,Itga5,Hk1,Fscn1,Cited2,Plod2,Mark2 |
| 4.511e-03 | -5.40 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_DN | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_DN | 34 | 8 | 15632 | 1249 |
Casp7,Sema4c,Gbe1,Plod2,Rbl1,Glrx,Pdgfc,Sdc2 |
| 4.527e-03 | -5.40 | T cell selection | biological process | GO:0045058 | 48 | 9 | 20694 | 1406 |
Cd74,Fas,Il15,Syk,Spn,Il6,Batf,Stat3,Irf4 |
| 4.527e-03 | -5.40 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | biological process | GO:0007157 | 48 | 9 | 20694 | 1406 |
Vcam1,Itga5,Nectin4,Itgal,Sele,Cd164,Pvr,Itga4,Lgals9 |
| 4.527e-03 | -5.40 | protein kinase C-activating G protein-coupled receptor signaling pathway | biological process | GO:0007205 | 24 | 6 | 20694 | 1406 |
Dgka,Adora2a,Dgkh,Cish,Edn1,Htr2b |
| 4.527e-03 | -5.40 | regulation of interleukin-6 biosynthetic process | biological process | GO:0045408 | 24 | 6 | 20694 | 1406 |
Tlr1,Tnf,Il1b,Ptafr,Stat3,Tlr6 |
| 4.527e-03 | -5.40 | regulation of gonad development | biological process | GO:1905939 | 24 | 6 | 20694 | 1406 |
Src,Abcb1a,Ptger4,Cited2,Nupr1,Il1a |
| 4.527e-03 | -5.40 | vascular endothelial growth factor receptor signaling pathway | biological process | GO:0048010 | 24 | 6 | 20694 | 1406 |
Ccl2,Kdr,Flt1,Mapkapk2,Pdgfb,Vegfc |
| 4.527e-03 | -5.40 | negative regulation of oxidative stress-induced neuron death | biological process | GO:1903204 | 24 | 6 | 20694 | 1406 |
Slc7a11,Fzd1,Ncoa7,Il10,Nr4a3,Hif1a |
| 4.534e-03 | -5.40 | exoribonuclease activity | molecular function | GO:0004532 | 31 | 7 | 20217 | 1400 |
Xrn1,Isg20,Zc3h12a,Pnpt1,Usb1,Dcp2,Noct |
| 4.545e-03 | -5.39 | INTEGRINA | prints domains | PR01185 | 18 | 5 | 5821 | 374 |
Itgav,Itga9,Itga4,Itga5,Itgal |
| 4.547e-03 | -5.39 | TNECROSISFCT | prints domains | PR01234 | 6 | 3 | 5821 | 374 |
Tnfsf14,Tnf,Tnfsf15 |
| 4.547e-03 | -5.39 | INTERLEUKIN1 | prints domains | PR00264 | 6 | 3 | 5821 | 374 |
Il1rn,Il1b,Il1a |
| 4.557e-03 | -5.39 | GO_MEMBRANE_REGION | MSigDB lists | GO_MEMBRANE_REGION | 1059 | 108 | 15632 | 1249 |
Sipa1l1,Slc7a8,Slc4a7,Pdgfb,Antxr1,Slc7a5,Tlr1,Ptgs2,Kcna3,Ptprj,Cd55,Plaur,Abcc4,P2ry12,Rgs14,Birc2,Slc2a1,Lipe,Src,Ehd1,Lrp4,Casp3,Rhoq,Spata13,Icam1,Ddx58,Fgr,Notch1,Myo10,Hck,Nod1,P2ry2,Ptch1,Birc3,Jag1,Met,Plscr1,Adrb2,Tlr2,Nox1,Prkar2b,Nlgn2,Tmem67,Cflar,Kdr,Ezr,Flrt3,Nod2,Spry2,Pdpn,Prnp,Tlr6,Lrp8,Atp2b4,Angpt1,Htr2a,Lcp2,Pdgfrb,Plek,Gja1,Myadm,Sh3bp4,Rapgef2,Vasp,Reps1,Piezo1,Phlpp2,Stxbp3,Fcho2,Hmox1,Pgk1,Traf2,Homer1,Tnf,Sele,Slc39a4,Cd14,Cav1,Casp8,Tnfrsf1b,Hk1,Ednrb,Syne2,Kctd12,Slc9a1,Cacnb3,Itga9,Lyn,Pdzd11,Sema4c,Mtdh,Tlr9,Ptk2,Itga5,Abcc1,Fscn1,Arf4,Jak2,Ldlr,Ppp2r1b,Itgav,Pikfyve,Fas,Spred1,Olr1,Sdc4,Cd34,Gpc1 |
| 4.575e-03 | -5.39 | WHITFIELD_CELL_CYCLE_G2 | MSigDB lists | WHITFIELD_CELL_CYCLE_G2 | 161 | 23 | 15632 | 1249 |
Cflar,Ebi3,Uaca,Stat1,Cdc42ep4,Sap30,Met,Tuba4a,Cep350,Ciita,Rgs3,Kdm4a,Arl4a,Casp3,Nr3c1,Katna1,Ncoa5,Mid1,Hspa2,Cxcl14,Klf6,Ifnar1,Timp1 |
| 4.575e-03 | -5.39 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN | 161 | 23 | 15632 | 1249 |
Cd82,Pde3b,Hck,Dram1,Ptgir,Cd200,Parp3,Zfp281,Csf1,Ext1,Nr3c1,Aftph,Cnot4,Stx11,Dcp1a,Cx3cr1,Plek,Dusp1,Aoah,Bcl6,Cd302,Ptch1,Trip10 |
| 4.575e-03 | -5.39 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_DN | 161 | 23 | 15632 | 1249 |
Prkar2b,Prkx,Nr4a3,Asb13,Mmp25,Mppe1,Endod1,Stx11,Zfp36,Klf2,Tshz1,Pdk3,Tle3,Klf7,Slc48a1,Mpp7,Itga4,Slc39a4,P2ry13,Psmb9,Nr4a1,Ezr,Gsdmd |
| 4.575e-03 | -5.39 | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | 161 | 23 | 15632 | 1249 |
Slc4a7,Irf8,Flnb,Pstpip2,Csf1,Dgka,Dck,Endod1,Fam111a,Pik3cd,Ust,Gca,Cd82,Notch2,Sp110,Spn,Stap1,Hhex,Kmo,Cd74,Clec4e,Traf5,Klf7 |
| 4.581e-03 | -5.39 | GO_RECEPTOR_COMPLEX | MSigDB lists | GO_RECEPTOR_COMPLEX | 317 | 39 | 15632 | 1249 |
Ahr,Olr1,Notch1,Cd14,Bmp2,Traf5,Il4ra,Nr1h3,Cd74,Tlr6,Lrp8,Itga4,Acvr1,Rffl,Itgb8,Il6,Gpr84,Birc2,Cd40,Traf2,Itgav,Syk,Flt1,Igf1r,Ldlr,Notch2,Lyn,Adrb2,Tlr2,Acvr1b,Itga9,Itga5,Il13ra1,Il12rb1,Tlr1,Nrp2,Itgal,Ahrr,Rnf31 |
| 4.599e-03 | -5.38 | miRNA regulation of DNA Damage Response | WikiPathways | WP2087 | 65 | 15 | 4813 | 540 |
Gadd45g,Mdm2,Casp3,Tlk2,Apaf1,Fas,Ccnd2,Ccne1,Casp8,Ccnd1,Cdkn1a,Pml,Pmaip1,Atm,Gadd45b |
| 4.601e-03 | -5.38 | GO_EARLY_ENDOSOME | MSigDB lists | GO_EARLY_ENDOSOME | 277 | 35 | 15632 | 1249 |
Pml,H2-Q7,Pikfyve,Arrdc4,Atp11a,Fcgr1,Lipg,Sgk3,Atp11b,Plekhf2,Ehd1,H2-Q4,Rab32,H2-Q6,Dbnl,Rab21,Tlr3,Nox1,Adrb2,Kdr,Ldlr,Vcam1,Pmepa1,Gja1,Lnpep,Rabgef1,P2ry2,Map2k1,Cav1,Fzd5,Myo1b,Wdfy1,Inpp5b,Stx6,Snx2 |
| 4.604e-03 | -5.38 | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | MSigDB lists | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | 98 | 16 | 15632 | 1249 |
Osgin2,Kmo,Dusp5,Cpeb4,Etnk1,Cd55,Glrx,Lrp11,Prdx1,Txnrd1,Gja1,Errfi1,Vcan,Arhgap26,Pla2g4a,Sat1 |
| 4.608e-03 | -5.38 | SCF(Skp2)-mediated degradation of p27/p21 | REACTOME pathways | R-MMU-187577 | 59 | 12 | 8608 | 757 |
Psmb9,Psme1,Ccnd1,Psmb6,Psmb10,Cdkn1a,Psmb8,Ccne1,Psmd10,Psme2b,Psme2,Psma6 |
| 4.609e-03 | -5.38 | glutamate-cysteine ligase complex | cellular component | GO:0017109 | 2 | 2 | 20747 | 1409 |
Gclc,Gclm |
| 4.609e-03 | -5.38 | stereocilium shaft | cellular component | GO:0120043 | 2 | 2 | 20747 | 1409 |
Triobp,Fchsd2 |
| 4.609e-03 | -5.38 | Toll-like receptor 1-Toll-like receptor 2 protein complex | cellular component | GO:0035354 | 2 | 2 | 20747 | 1409 |
Tlr2,Tlr1 |
| 4.609e-03 | -5.38 | integrin alphav-beta8 complex | cellular component | GO:0034686 | 2 | 2 | 20747 | 1409 |
Itgav,Itgb8 |
| 4.609e-03 | -5.38 | Toll-like receptor 2-Toll-like receptor 6 protein complex | cellular component | GO:0035355 | 2 | 2 | 20747 | 1409 |
Tlr2,Tlr6 |
| 4.613e-03 | -5.38 | negative regulation of response to macrophage colony-stimulating factor | biological process | GO:1903970 | 2 | 2 | 20694 | 1406 |
Ptpn2,Stap1 |
| 4.613e-03 | -5.38 | tripeptide transmembrane transport | biological process | GO:0035443 | 2 | 2 | 20694 | 1406 |
Slc7a11,Abcc1 |
| 4.613e-03 | -5.38 | interleukin-13-mediated signaling pathway | biological process | GO:0035772 | 2 | 2 | 20694 | 1406 |
Cd300lf,Il13ra1 |
| 4.613e-03 | -5.38 | negative regulation of mast cell cytokine production | biological process | GO:0032764 | 2 | 2 | 20694 | 1406 |
Bcl6,Hmox1 |
| 4.613e-03 | -5.38 | positive regulation of miRNA catabolic process | biological process | GO:2000627 | 2 | 2 | 20694 | 1406 |
Pnpt1,Zc3h12a |
| 4.613e-03 | -5.38 | detection of triacyl bacterial lipopeptide | biological process | GO:0042495 | 2 | 2 | 20694 | 1406 |
Tlr2,Tlr1 |
| 4.613e-03 | -5.38 | nucleotide-binding oligomerization domain containing 1 signaling pathway | biological process | GO:0070427 | 2 | 2 | 20694 | 1406 |
Ripk2,Nfkbia |
| 4.613e-03 | -5.38 | positive regulation of phenotypic switching | biological process | GO:1900241 | 2 | 2 | 20694 | 1406 |
Sod2,Pdgfb |
| 4.613e-03 | -5.38 | negative regulation of macrophage colony-stimulating factor signaling pathway | biological process | GO:1902227 | 2 | 2 | 20694 | 1406 |
Ptpn2,Stap1 |
| 4.613e-03 | -5.38 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | biological process | GO:0002479 | 2 | 2 | 20694 | 1406 |
Tap1,Tapbp |
| 4.613e-03 | -5.38 | cellular response to mycophenolic acid | biological process | GO:0071506 | 2 | 2 | 20694 | 1406 |
Pdgfb,Egr1 |
| 4.613e-03 | -5.38 | negative regulation of hippocampal neuron apoptotic process | biological process | GO:0110091 | 2 | 2 | 20694 | 1406 |
Cx3cl1,Cx3cr1 |
| 4.613e-03 | -5.38 | endocardial cushion cell differentiation | biological process | GO:0061443 | 2 | 2 | 20694 | 1406 |
Jag1,Acvr1 |
| 4.613e-03 | -5.38 | positive regulation of growth factor dependent skeletal muscle satellite cell proliferation | biological process | GO:1902728 | 2 | 2 | 20694 | 1406 |
Jak2,Stat3 |
| 4.613e-03 | -5.38 | susceptibility to T cell mediated cytotoxicity | biological process | GO:0060370 | 2 | 2 | 20694 | 1406 |
Nectin2,Pvr |
| 4.613e-03 | -5.38 | cellular response to progesterone stimulus | biological process | GO:0071393 | 2 | 2 | 20694 | 1406 |
Acod1,Src |
| 4.613e-03 | -5.38 | metanephric glomerular mesangium development | biological process | GO:0072223 | 2 | 2 | 20694 | 1406 |
Pdgfb,Pdgfrb |
| 4.613e-03 | -5.38 | tolerance induction to lipopolysaccharide | biological process | GO:0072573 | 2 | 2 | 20694 | 1406 |
Acod1,Tnfaip3 |
| 4.613e-03 | -5.38 | regulation of chronic inflammatory response to non-antigenic stimulus | biological process | GO:0002880 | 2 | 2 | 20694 | 1406 |
Adora2b,Cx3cr1 |
| 4.613e-03 | -5.38 | glutathione transmembrane transport | biological process | GO:0034775 | 2 | 2 | 20694 | 1406 |
Abcc1,Slc7a11 |
| 4.613e-03 | -5.38 | positive regulation of skeletal muscle satellite cell proliferation | biological process | GO:1902724 | 2 | 2 | 20694 | 1406 |
Jak2,Stat3 |
| 4.613e-03 | -5.38 | detection of diacyl bacterial lipopeptide | biological process | GO:0042496 | 2 | 2 | 20694 | 1406 |
Tlr2,Tlr6 |
| 4.613e-03 | -5.38 | cell-cell adhesion in response to extracellular stimulus | biological process | GO:0140039 | 2 | 2 | 20694 | 1406 |
Vcam1,Itga4 |
| 4.613e-03 | -5.38 | positive regulation of interleukin-4-mediated signaling pathway | biological process | GO:1902216 | 2 | 2 | 20694 | 1406 |
Cd300lf,Parp14 |
| 4.613e-03 | -5.38 | metanephric glomerular mesangial cell proliferation involved in metanephros development | biological process | GO:0072262 | 2 | 2 | 20694 | 1406 |
Pdgfb,Pdgfrb |
| 4.613e-03 | -5.38 | regulation of activated CD8-positive, alpha-beta T cell apoptotic process | biological process | GO:1905402 | 2 | 2 | 20694 | 1406 |
Cd274,Arg2 |
| 4.613e-03 | -5.38 | negative regulation of cellular response to macrophage colony-stimulating factor stimulus | biological process | GO:1903973 | 2 | 2 | 20694 | 1406 |
Ptpn2,Stap1 |
| 4.613e-03 | -5.38 | positive regulation of protein K48-linked ubiquitination | biological process | GO:1902524 | 2 | 2 | 20694 | 1406 |
Birc2,Nmi |
| 4.613e-03 | -5.38 | response to mycophenolic acid | biological process | GO:0071505 | 2 | 2 | 20694 | 1406 |
Pdgfb,Egr1 |
| 4.613e-03 | -5.38 | regulation of calcium-independent cell-cell adhesion | biological process | GO:0051040 | 2 | 2 | 20694 | 1406 |
Cx3cl1,Bmp2 |
| 4.613e-03 | -5.38 | positive regulation of myeloid dendritic cell activation | biological process | GO:0030887 | 2 | 2 | 20694 | 1406 |
Clec4d,Klrk1 |
| 4.613e-03 | -5.38 | angiotensin-activated signaling pathway involved in heart process | biological process | GO:0086098 | 2 | 2 | 20694 | 1406 |
Cav1,Src |
| 4.613e-03 | -5.38 | interferon-gamma biosynthetic process | biological process | GO:0042095 | 2 | 2 | 20694 | 1406 |
Gadd45g,Il18 |
| 4.619e-03 | -5.38 | Class A/1 (Rhodopsin-like receptors) | REACTOME pathways | R-MMU-373076 | 299 | 40 | 8608 | 757 |
S1pr2,P2ry12,Pf4,Ccr3,Cxcl10,P2ry14,Fpr1,Adrb2,Edn1,Cxcl1,Cxcl9,Cxcl2,Htr2a,Cx3cr1,Adora2a,Gpr35,Ccl5,Cxcl3,Gpr68,Adora2b,Gpr18,Ccl9,Prokr1,Ptgir,Htr2b,Gpr132,Fpr2,Ednrb,P2ry2,C3,Cxcl11,Ptafr,Hcar2,Ccrl2,P2ry13,Ptger4,Cx3cl1,Lpar1,Cysltr2,Xcr1 |
| 4.629e-03 | -5.38 | FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP | MSigDB lists | FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP | 81 | 14 | 15632 | 1249 |
Tcf4,Lcp2,Cx3cr1,Slc7a5,Stat3,Ikzf1,Sell,Fgr,Il2rg,Tnfaip3,Nfil3,Ralgds,Cd34,Prdx1 |
| 4.629e-03 | -5.38 | pyruvate metabolic process | biological process | GO:0006090 | 66 | 11 | 20694 | 1406 |
Ldha,Hk3,Pfkl,Me1,Hk2,Hk1,Nr4a3,Tpi1,Pcx,Eno2,Pgk1 |
| 4.629e-03 | -5.38 | regulation of protein maturation | biological process | GO:1903317 | 66 | 11 | 20694 | 1406 |
Birc3,Cst7,Inpp5b,Serpine1,Mmp14,Ctla2a,Rnf139,Src,Birc2,Thbs1,Mdm2 |
| 4.648e-03 | -5.37 | GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_UP | MSigDB lists | GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_UP | 199 | 27 | 15632 | 1249 |
Mthfd2,Ldha,Hmgcs1,Pgk1,Nfil3,Cflar,Asns,Eno2,Stx11,Eef1e1,Il18rap,Timeless,Sap30,Tpx2,Traf1,Gbe1,Pttg1,Ccnd2,Tpi1,Prdx1,Eno1,Psmb9,Srm,Cst7,Psma6,Pnp2,Phgdh |
| 4.650e-03 | -5.37 | ubiquitin binding | molecular function | GO:0043130 | 74 | 12 | 20217 | 1400 |
Tnfaip3,Dnajb2,Rnf31,Ikbkg,Ube2l6,Rnf19b,Optn,Uchl1,Mdm2,Birc2,Sqstm1,Tax1bp1 |
| 4.657e-03 | -5.37 | GSE3982_NEUTROPHIL_VS_TH2_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH2_UP | 180 | 25 | 15632 | 1249 |
Apaf1,Hk3,Pfkfb3,Clec4e,Htr2a,Arl4a,Tlr6,Ogfrl1,Ifnb1,Serp1,Ifit2,Parp8,Abcc5,Trem1,Sec24b,Zcchc2,Mppe1,Mmp25,Rnf19b,Xaf1,Syne2,Pstpip2,Tor1aip1,Dach1,Ltbp2 |
| 4.657e-03 | -5.37 | CHANG_CORE_SERUM_RESPONSE_DN | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_DN | 180 | 25 | 15632 | 1249 |
Arid5b,Hmgcs1,Cdkn1a,Idi1,Ldlr,Tnfaip2,Cd82,C1rl,Jag1,Slpi,Csf1,Caml,Xrn1,Fabp3,Nupr1,Irak3,F10,Bcl6,Arhgef3,Sod2,Ccng2,4932438A13Rik,Errfi1,Kdm5b,Parp14 |
| 4.657e-03 | -5.37 | GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_UP | MSigDB lists | GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_UP | 180 | 25 | 15632 | 1249 |
Agrn,Stat5a,Acvrl1,Ogfrl1,Fchsd2,Irf4,Tpx2,Cd74,Slc30a4,Hhex,Angpt1,Gng11,Lpcat2,Pilrb2,Cd34,Ppm1k,Maff,H2-Aa,Mefv,Pim2,Egr3,Htr2b,Agpat4,Tmem67,Pilrb1 |
| 4.657e-03 | -5.37 | GSE12198_LOW_IL2_STIM_NK_CELL_VS_HIGH_IL2_STIM_NK_CELL_UP | MSigDB lists | GSE12198_LOW_IL2_STIM_NK_CELL_VS_HIGH_IL2_STIM_NK_CELL_UP | 180 | 25 | 15632 | 1249 |
Ext1,Trim21,Btg2,Vasn,Rasgrp1,Samsn1,Ikbke,Epsti1,Igf1r,Sec24b,Frmd6,Larp1,Mtdh,Trib1,Ms4a6d,Chic2,Ttc39b,Psd,Tlk2,Gadd45b,Tnf,Ppp1r14b,Lrp4,Hif1a,Fam133b |
| 4.657e-03 | -5.37 | GSE4748_CTRL_VS_LPS_STIM_DC_3H_DN | MSigDB lists | GSE4748_CTRL_VS_LPS_STIM_DC_3H_DN | 180 | 25 | 15632 | 1249 |
Glrx,Gcnt2,Tgfbi,Odc1,Hmox1,Rnf19b,St3gal1,Stat4,Ociad1,Nampt,S100a8,Rgl1,Me1,Slc48a1,Rbms2,Batf,Arrdc4,Col18a1,Atf3,Pcx,Gadd45g,Tor1aip2,Dusp1,Gadd45b,Nr4a1 |
| 4.657e-03 | -5.37 | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_DN | MSigDB lists | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_DN | 180 | 25 | 15632 | 1249 |
Adam19,Cacna1d,Cdkn1a,Esd,Trip13,Isg20,Sap30,Pou2f2,Fam72a,Wars,Hivep3,Car13,Ccne1,Plod2,Dusp14,Dnase1l3,Tpi1,Mcm10,Hhex,Tpx2,Ifi44,Egr2,Ap3b1,Plac8,Cenpe |
| 4.657e-03 | -5.37 | GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_UP | 180 | 25 | 15632 | 1249 |
Gtpbp2,Idi1,Asf1a,Acvr1b,Frmd4a,Smc5,Filip1l,Rnf19a,Trim56,Rasgrp1,Ampd3,Ppm1k,Ptch1,Jarid2,Cd164,Tulp3,Rtp4,Cept1,Rsad2,Parp9,Parp14,Egr2,D16Ertd472e,Bcl2l11,Sod2 |
| 4.657e-03 | -5.37 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_UP | 180 | 25 | 15632 | 1249 |
Samsn1,Rap1gap2,Ifna6,Pim1,Dram1,Xkr8,Atp10a,Tnfsf4,Cd55,Timp1,Plac8,Casp1,Ifna5,Slc15a3,Ifi44,Cd74,Sell,Notch1,Mdfic,Ifna2,Rras2,Ifna1,Pde3b,Pbx1,Gng11 |
| 4.657e-03 | -5.37 | GSE14308_TH2_VS_NATURAL_TREG_DN | MSigDB lists | GSE14308_TH2_VS_NATURAL_TREG_DN | 180 | 25 | 15632 | 1249 |
Clcn7,Zhx2,Cmpk2,Ppp2r2a,Cxcl10,Rcsd1,Acvr1b,Ext1,Rnf31,Nfkb1,Sesn3,Jarid2,Mcm9,Tap2,Pnpt1,Lrch3,Slc30a1,Pttg1,Stard5,Ikzf1,Nfkbie,Ctu1,Gadd45b,Tnf,Acpp |
| 4.657e-03 | -5.37 | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN | 180 | 25 | 15632 | 1249 |
Adam19,Pilrb1,Osbpl3,Tfec,Lrrc8c,Ppa1,Atp10a,Mtmr14,Sema4a,Timeless,Inpp5b,Tdrd7,Tyk2,Sirt1,Sh3bp4,Tuba4a,Pilrb2,Rbl1,Apaf1,Stap1,S1pr2,Ifnar1,Bcl2l11,Parp8,Ifit2 |
| 4.657e-03 | -5.37 | GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_DN | MSigDB lists | GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_DN | 180 | 25 | 15632 | 1249 |
Cxcl2,Dcp1a,Casp2,Stat4,Stxbp3,Gem,Plekha2,Myadm,Ccne1,Birc3,Dek,Smc5,Etnk1,Ccng2,Mecp2,Lztfl1,4932438A13Rik,Birc2,Cyfip1,Spryd7,Ube2f,Il15,Mpp7,Fam133b,Atp11a |
| 4.669e-03 | -5.37 | neural crest cell migration | biological process | GO:0001755 | 57 | 10 | 20694 | 1406 |
Acvr1,Kitl,Sema4a,Htr2b,Ednrb,Sema4c,Hif1a,Nrp2,Sema3c,Phactr4 |
| 4.675e-03 | -5.37 | GSE37534_GW1929_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN | MSigDB lists | GSE37534_GW1929_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN | 152 | 22 | 15632 | 1249 |
Mmp9,Fam53c,Ch25h,Arl4a,Mpp7,Ifit3b,Gbp3,Fcho2,Calcrl,Elmod2,Zhx2,Tnks1bp1,Slc37a3,Epsti1,Vps54,Ankrd17,Ptpn2,Ifit3,Spen,Egln3,Rictor,Arhgap26 |
| 4.675e-03 | -5.37 | GO_REGENERATION | MSigDB lists | GO_REGENERATION | 152 | 22 | 15632 | 1249 |
Nr4a3,Adrb2,Socs1,Lif,Socs3,Fas,Cdkn1a,Notch1,Tspo,Jak2,Plau,Cflar,Notch2,Jun,Cav1,Ccne1,Gja1,Ccl12,Ifrd1,Ccnd1,Tnc,Bcl9 |
| 4.675e-03 | -5.37 | GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 152 | 22 | 15632 | 1249 |
Kif9,Ncoa7,Hp,St3gal1,St3gal3,Kat2b,Stat2,Kmo,Mob3b,Rcsd1,Adrb2,Spire1,Trim21,Tbc1d1,Pla2g4a,Ampd3,Fchsd2,Pla2g7,Pde5a,Psd4,Rgs14,Csf3r |
| 4.697e-03 | -5.36 | regulation of protein tyrosine kinase activity | biological process | GO:0061097 | 85 | 13 | 20694 | 1406 |
Lrp8,Mvp,Cav1,Stap1,Errfi1,Pdgfb,Rap2c,Agrn,Prnp,Ptpn2,Fcgr1,Fam72a,Hsph1 |
| 4.729e-03 | -5.35 | MODULE_23 | MSigDB lists | MODULE_23 | 525 | 59 | 15632 | 1249 |
Phyh,Ak4,Tgfbi,Hp,Glrx,Plat,Serpine1,Psd4,Ifit1bl2,Hap1,Stoml1,Ube2l6,Fgr,Isg15,Atp11a,Stat2,Mthfr,Nupr1,Plk3,Nfkbil1,Cd14,Pbx1,Slc2a1,Cst7,Tnf,Ccnd1,Sele,Cp,Acsl1,Trib1,Rac3,Itga5,Ptch1,Tnfrsf1b,Ikbkg,Casp2,Smpdl3b,Slpi,Nfkbib,Alas1,Procr,Aldh1b1,Cdk5r1,Il4ra,Sdc1,Col18a1,Dnase1l3,Atp2b4,Tnfrsf14,Htr2a,F10,Cd34,Cited2,Ccl12,Slc7a11,Gadd45b,Ifit1bl1,Pcx,Stard5 |
| 4.737e-03 | -5.35 | TBK1.DN.48HRS_DN | MSigDB lists | TBK1.DN.48HRS_DN | 49 | 10 | 15632 | 1249 |
Dck,Il13ra1,Psmb8,Birc2,Ier3,Atp6v1d,Trib3,Gna15,St3gal5,Dusp4 |
| 4.737e-03 | -5.35 | GO_REGULATION_OF_MYOTUBE_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_MYOTUBE_DIFFERENTIATION | 49 | 10 | 15632 | 1249 |
Gdf15,Ehd1,Cxcl10,Il4ra,Tnfsf14,Mmp14,Cflar,Daxx,Notch1,Hdac1 |
| 4.737e-03 | -5.35 | PID_PI3KCI_PATHWAY | MSigDB lists | PID_PI3KCI_PATHWAY | 49 | 10 | 15632 | 1249 |
Hck,Cyth3,Plekha2,Fgr,Pik3cd,Lyn,Pik3r6,Src,Syk,Pik3r5 |
| 4.737e-03 | -5.35 | GERHOLD_ADIPOGENESIS_UP | MSigDB lists | GERHOLD_ADIPOGENESIS_UP | 49 | 10 | 15632 | 1249 |
Stat3,Gclm,Pcx,Stat1,Ldha,Ppa1,Sqstm1,Stat5a,Lipe,Acsl1 |
| 4.741e-03 | -5.35 | Ikbkg (inhibitor of kappaB kinase gamma) | protein interactions | 16151 | 41 | 10 | 7778 | 753 |
Nfkbia,Nfkbiz,Hspa1b,Nfkbib,Traf2,Rnf31,Tnfaip3,Cd40,Tnf,Ikbkg |
| 4.748e-03 | -5.35 | cell trailing edge | cellular component | GO:0031254 | 11 | 4 | 20747 | 1409 |
Ezr,Scimp,Bst1,Spn |
| 4.748e-03 | -5.35 | uropod | cellular component | GO:0001931 | 11 | 4 | 20747 | 1409 |
Scimp,Ezr,Bst1,Spn |
| 4.754e-03 | -5.35 | GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_UP | MSigDB lists | GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_UP | 143 | 21 | 15632 | 1249 |
Trim21,Pnp2,Il12rb1,Hivep3,Scarf1,Dync1h1,Nlrc5,Tnf,Card6,Marco,Sipa1l1,Clcn7,1600014C10Rik,Stat1,Tlr6,Slamf8,Cd74,Usp42,Pttg1,Ccnd2,Rtp4 |
| 4.754e-03 | -5.35 | KATSANOU_ELAVL1_TARGETS_DN | MSigDB lists | KATSANOU_ELAVL1_TARGETS_DN | 143 | 21 | 15632 | 1249 |
Fgl2,Ifi203,Ifi211,Timeless,Ifi208,Daam1,Layn,Ets2,Ifi205,Ifi209,Mndal,Ifi213,Clmp,Fmnl2,Ifi207,Serpinb2,Tgfbi,Ifi204,Ifi214,St3gal6,Kif5c |
| 4.755e-03 | -5.35 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | biological process | GO:0006977 | 11 | 4 | 20694 | 1406 |
Casp2,Pml,Cdkn1a,Mdm2 |
| 4.755e-03 | -5.35 | negative regulation of heterotypic cell-cell adhesion | biological process | GO:0034115 | 11 | 4 | 20694 | 1406 |
Il10,Tnfaip3,Il1rn,Myadm |
| 4.755e-03 | -5.35 | interleukin-1 secretion | biological process | GO:0050701 | 11 | 4 | 20694 | 1406 |
Nlrc4,Nlrp3,Aim2,Tlr6 |
| 4.755e-03 | -5.35 | regulation of CD4-positive, alpha-beta T cell proliferation | biological process | GO:2000561 | 11 | 4 | 20694 | 1406 |
Arg2,Cd274,Lgals9,Tarm1 |
| 4.755e-03 | -5.35 | regulation of humoral immune response mediated by circulating immunoglobulin | biological process | GO:0002923 | 11 | 4 | 20694 | 1406 |
Cd55,Nod2,Fcgr2b,Tnf |
| 4.755e-03 | -5.35 | growth hormone receptor signaling pathway | biological process | GO:0060396 | 11 | 4 | 20694 | 1406 |
Ptk2,Stat5a,Jak2,Stat3 |
| 4.755e-03 | -5.35 | regulation of natural killer cell mediated immune response to tumor cell | biological process | GO:0002855 | 11 | 4 | 20694 | 1406 |
Pvr,Klrk1,Il12b,Nectin2 |
| 4.755e-03 | -5.35 | cellular response to growth hormone stimulus | biological process | GO:0071378 | 11 | 4 | 20694 | 1406 |
Stat5a,Ptk2,Stat3,Jak2 |
| 4.755e-03 | -5.35 | positive regulation of glial cell migration | biological process | GO:1903977 | 11 | 4 | 20694 | 1406 |
P2ry12,Crkl,Fubp1,Csf1 |
| 4.755e-03 | -5.35 | positive regulation of macrophage derived foam cell differentiation | biological process | GO:0010744 | 11 | 4 | 20694 | 1406 |
Pf4,Il18,Msr1,Csf1 |
| 4.755e-03 | -5.35 | positive regulation of cell aging | biological process | GO:0090343 | 11 | 4 | 20694 | 1406 |
Eef1e1,Cgas,Sirt1,Arg2 |
| 4.755e-03 | -5.35 | regulation of cell-cell adhesion involved in gastrulation | biological process | GO:0070587 | 11 | 4 | 20694 | 1406 |
Il10,Tnfaip3,Il1rn,Myadm |
| 4.755e-03 | -5.35 | positive regulation of monocyte chemotactic protein-1 production | biological process | GO:0071639 | 11 | 4 | 20694 | 1406 |
Nod2,Mcoln2,Il1a,Il1b |
| 4.792e-03 | -5.34 | glutamate-cysteine ligase activity | molecular function | GO:0004357 | 2 | 2 | 20217 | 1400 |
Gclc,Gclm |
| 4.792e-03 | -5.34 | tapasin binding | molecular function | GO:0046980 | 2 | 2 | 20217 | 1400 |
Tap2,Tap1 |
| 4.792e-03 | -5.34 | ATPase-coupled peptide antigen transmembrane transporter activity | molecular function | GO:0015433 | 2 | 2 | 20217 | 1400 |
Tap1,Tap2 |
| 4.792e-03 | -5.34 | NAD(P)+ nucleosidase activity | molecular function | GO:0050135 | 2 | 2 | 20217 | 1400 |
Cd38,Bst1 |
| 4.792e-03 | -5.34 | triacyl lipopeptide binding | molecular function | GO:0042497 | 2 | 2 | 20217 | 1400 |
Tlr2,Tlr1 |
| 4.792e-03 | -5.34 | NAD+ nucleotidase, cyclic ADP-ribose generating | molecular function | GO:0061809 | 2 | 2 | 20217 | 1400 |
Bst1,Cd38 |
| 4.792e-03 | -5.34 | diacyl lipopeptide binding | molecular function | GO:0042498 | 2 | 2 | 20217 | 1400 |
Tlr6,Tlr2 |
| 4.792e-03 | -5.34 | left-handed Z-DNA binding | molecular function | GO:0003692 | 2 | 2 | 20217 | 1400 |
Zbp1,Adar |
| 4.800e-03 | -5.34 | GO_CELL_LEADING_EDGE | MSigDB lists | GO_CELL_LEADING_EDGE | 328 | 40 | 15632 | 1249 |
Ddx58,Spata13,Cyth3,Fgr,Evl,Palld,Asap3,Rab3ip,Myo10,Swap70,Cyfip1,Ezr,Src,Itgav,Psd,Phactr4,Spry2,Dbnl,Pdpn,Mefv,Ptk2,Ptprj,Mtmr14,Rac3,Itga5,Fscn1,Arf4,Samsn1,Layn,Lmo4,Plek,Myadm,Slc39a14,Snx2,Syne2,Vasp,Slc9a1,Antxr1,Pdlim7,Piezo1 |
| 4.804e-03 | -5.34 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_DN | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_DN | 171 | 24 | 15632 | 1249 |
Dennd1b,Stap1,Mdn1,Fut8,Casp3,Nr3c1,Rab21,Ccng2,Dock10,Kdm5b,Psip1,Plekhf2,Bmp2,Traf5,Zbtb5,Col18a1,Nr1h3,Cyth3,Zc3h7a,Ext1,Eif4g2,Dach1,Nfkb2,Orai2 |
| 4.804e-03 | -5.34 | AAAGGAT_MIR501 | MSigDB lists | AAAGGAT_MIR501 | 116 | 18 | 15632 | 1249 |
Rsbn1,Rpgrip1l,Cd164,Nfil3,Larp1,Rcn1,Phf6,Map3k8,Nr4a3,Zc3h7a,Prkce,Usp12,Errfi1,Rgl1,Rabgef1,Bcl6,Jun,Map2k1 |
| 4.805e-03 | -5.34 | STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_UP | MSigDB lists | STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_UP | 73 | 13 | 15632 | 1249 |
Dio2,Pde3b,Rbms1,Plcl2,Socs3,Prdm1,Cp,Wdfy1,Ttc39c,Slc4a7,Ifit1bl2,Ifit1bl1,Pde4b |
| 4.806e-03 | -5.34 | MORF_PML | MSigDB lists | MORF_PML | 134 | 20 | 15632 | 1249 |
Slc9a1,Gpr35,Cnot4,Tra2a,Casp2,Itgav,Ikbkg,Cnp,Rbbp8,Sik3,Slc2a1,Mgat1,Cd40,Ikbke,Plk3,Irf2,Pml,Cdk5r1,Mmp25,Slc30a1 |
| 4.806e-03 | -5.34 | GO_RESPONSE_TO_TRANSITION_METAL_NANOPARTICLE | MSigDB lists | GO_RESPONSE_TO_TRANSITION_METAL_NANOPARTICLE | 134 | 20 | 15632 | 1249 |
Ppp1r15a,S100a8,Nfkb1,Ass1,Ccne1,Ccnd1,Mdm2,Pla2g4a,Cp,Il1a,Icam1,Prnp,Ptgs2,Slc30a1,Slc30a4,Slc31a1,Hmox1,Hvcn1,Vcam1,Tspo |
| 4.809e-03 | -5.34 | ABC_membrane | pfam domains | PF00664 | 23 | 6 | 18711 | 1348 |
Abcc5,Abcb1a,Tap1,Tap2,Abcc1,Abcc4 |
| 4.823e-03 | -5.33 | IBR | smart domains | SM00647 | 14 | 5 | 9567 | 823 |
Rnf19b,Rnf19a,Rnf31,Ankib1,Rnf14 |
| 4.829e-03 | -5.33 | GSE17721_POLYIC_VS_CPG_12H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_12H_BMDC_DN | 190 | 26 | 15632 | 1249 |
Adora2b,Acvr1b,Mefv,Mtdh,Slc31a1,Denr,Traf3ip2,Abcc1,Plat,Lmo4,Slc7a2,Eif4g2,Gdf15,Car13,Rab10,Pstpip2,Pdlim7,Fam133b,Jmjd6,Hck,Aoah,Ctu1,Spryd7,Srm,Ccl2,Dusp2 |
| 4.829e-03 | -5.33 | GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_DN | MSigDB lists | GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_DN | 190 | 26 | 15632 | 1249 |
Prdx1,Hif1a,Slc30a1,Minpp1,Pdpn,Sdc2,Txnrd1,Tiparp,Jun,Kdr,Serpinb2,Tnfaip2,Asf1a,Plaur,Esd,Tgfbi,Pim1,Clec4d,Srxn1,Wars,Mmp13,Maff,Birc3,Ccr1,Ubr4,Lcn2 |
| 4.829e-03 | -5.33 | GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_UP | 190 | 26 | 15632 | 1249 |
Pou2f2,Wars,Stat4,Tlr1,Procr,Inpp5b,Adap2,Map2k1,Junb,Rbms1,Ier3,Map3k8,Zc3h12a,Hp,Phlpp1,Nfkbie,Ankrd17,Sod2,Plekha5,Gypc,Casp1,Mcmbp,Cd14,Sla,Pilra,Hhex |
| 4.841e-03 | -5.33 | development of primary female sexual characteristics | biological process | GO:0046545 | 105 | 15 | 20694 | 1406 |
Angpt1,Src,Sirt1,Tiparp,Arid5b,Pla2g4a,Dach1,Kdr,Atm,Ahr,Nos2,Serpine1,Kitl,Inhba,Stat5a |
| 4.841e-03 | -5.33 | negative regulation of ion transmembrane transport | biological process | GO:0034766 | 105 | 15 | 20694 | 1406 |
Prkce,Tnf,Ahr,Irs2,Cav1,Crbn,Gem,Agrn,Stoml1,Mmp9,Gpr35,Slc30a1,Tlr9,Cacnb3,Thbs1 |
| 4.843e-03 | -5.33 | pattern recognition receptor activity | molecular function | GO:0038187 | 17 | 5 | 20217 | 1400 |
Tlr9,Tlr2,Ptafr,Trim12c,Clec4e |
| 4.849e-03 | -5.33 | positive regulation of muscle hypertrophy | biological process | GO:0014742 | 40 | 8 | 20694 | 1406 |
Ptk2,Trip10,Nr4a3,Nr3c1,Pde5a,Slc9a1,Sirt1,Edn1 |
| 4.853e-03 | -5.33 | Sphingolipid signaling pathway | KEGG pathways | ko04071 | 120 | 20 | 7931 | 713 |
Prkce,Ppp2r3a,Ppp2r2a,Akt3,Asah2,Sphk1,Abcc1,Nfkb1,S1pr2,Cers6,Sgms2,Rac3,Tnf,Ppp2r1b,Ppp2r5a,Traf2,Map2k1,Degs2,Pik3cd,Nsmaf |
| 4.853e-03 | -5.33 | Sphingolipid signaling pathway | KEGG pathways | mmu04071 | 120 | 20 | 7931 | 713 |
Pik3cd,Map2k1,Degs2,Nsmaf,Ppp2r1b,Ppp2r5a,Traf2,Rac3,Tnf,Sgms2,Cers6,Sphk1,S1pr2,Nfkb1,Abcc1,Asah2,Akt3,Ppp2r2a,Ppp2r3a,Prkce |
| 4.900e-03 | -5.32 | GNF2_CASP8 | MSigDB lists | GNF2_CASP8 | 21 | 6 | 15632 | 1249 |
Parp8,Atm,Lcp2,Itgal,Ddx58,Casp8 |
| 4.900e-03 | -5.32 | HUI_MAPK14_TARGETS_UP | MSigDB lists | HUI_MAPK14_TARGETS_UP | 21 | 6 | 15632 | 1249 |
Dusp8,Gadd45g,Gng4,Prnp,Jun,Isg15 |
| 4.900e-03 | -5.32 | GO_HISTONE_DEMETHYLASE_ACTIVITY | MSigDB lists | GO_HISTONE_DEMETHYLASE_ACTIVITY | 21 | 6 | 15632 | 1249 |
Kdm4a,Kdm5b,Arid5b,Jmjd6,Kdm6b,Jarid2 |
| 4.900e-03 | -5.32 | GO_POSITIVE_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION | 21 | 6 | 15632 | 1249 |
Nod1,Abcb1a,Tap1,Tap2,Cd74,Nod2 |
| 4.900e-03 | -5.32 | MATZUK_SPERMATOGONIA | MSigDB lists | MATZUK_SPERMATOGONIA | 21 | 6 | 15632 | 1249 |
Apaf1,Etv5,Csf1,Ddx4,Gja1,Cdkn2d |
| 4.900e-03 | -5.32 | GO_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS | 21 | 6 | 15632 | 1249 |
Sec24a,Itgav,Edn1,Nr1h3,Hif1a,Hdac1 |
| 4.900e-03 | -5.32 | GO_REGULATION_OF_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION | 21 | 6 | 15632 | 1249 |
Il6,Txn1,Parp10,Jak2,Cdkn1a,Sirt1 |
| 4.900e-03 | -5.32 | REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING | MSigDB lists | REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING | 21 | 6 | 15632 | 1249 |
Cd80,Akt3,Map3k8,Rictor,Cd86,Trib3 |
| 4.900e-03 | -5.32 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | MSigDB lists | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | 21 | 6 | 15632 | 1249 |
H2-Aa,Vasp,Nck1,H2-Eb1,Evl,Lcp2 |
| 4.900e-03 | -5.32 | BIOCARTA_CTL_PATHWAY | MSigDB lists | BIOCARTA_CTL_PATHWAY | 21 | 6 | 15632 | 1249 |
H2-Q7,Fas,H2-Q4,H2-Q6,Icam1,Itgal |
| 4.900e-03 | -5.32 | STEGER_ADIPOGENESIS_UP | MSigDB lists | STEGER_ADIPOGENESIS_UP | 21 | 6 | 15632 | 1249 |
Hp,Lipe,Nr1h3,Acsl1,Cp,Mmd |
| 4.900e-03 | -5.32 | KANG_FLUOROURACIL_RESISTANCE_UP | MSigDB lists | KANG_FLUOROURACIL_RESISTANCE_UP | 21 | 6 | 15632 | 1249 |
Arid5b,Osbpl3,Cdkn1a,Nqo1,Lztfl1,H3f3b |
| 4.900e-03 | -5.32 | GO_ADENYLYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_ADENYLYLTRANSFERASE_ACTIVITY | 21 | 6 | 15632 | 1249 |
Oas1a,Oas2,Papss2,Oas3,Oas1g,Oasl1 |
| 4.900e-03 | -5.32 | Amoebiasis | KEGG pathways | ko05146 | 104 | 18 | 7931 | 713 |
Nfkb1,Serpinb9,Cd14,Nos2,Serpinb9b,Ptk2,Col4a2,Tlr2,Gna15,Casp3,Serpinb6b,Il10,Pik3cd,Il12b,Il1b,Tnf,Il6,Arg2 |
| 4.900e-03 | -5.32 | Amoebiasis | KEGG pathways | mmu05146 | 104 | 18 | 7931 | 713 |
Il10,Serpinb6b,Pik3cd,Il6,Arg2,Tnf,Il1b,Il12b,Serpinb9,Nfkb1,Cd14,Casp3,Gna15,Serpinb9b,Nos2,Ptk2,Tlr2,Col4a2 |
| 4.901e-03 | -5.32 | GO_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | MSigDB lists | GO_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | 57 | 11 | 15632 | 1249 |
Cav1,Dock4,Flt1,Edn1,Adora2b,Ptgs2,Calcrl,Ptafr,Sphk1,Adrb2,Ptger4 |
| 4.908e-03 | -5.32 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3 | 65 | 12 | 15632 | 1249 |
Tlr1,Slpi,Phgdh,Maff,Ifit2,Psat1,Jun,Serpine1,Lcn2,Rhoc,Nupr1,Mcm6 |
| 4.908e-03 | -5.32 | DITTMER_PTHLH_TARGETS_DN | MSigDB lists | DITTMER_PTHLH_TARGETS_DN | 65 | 12 | 15632 | 1249 |
Ptk2,Casp1,Serpine1,Tbc1d1,Rras2,Spen,Sap30,Sec24a,Timeless,Rapgef2,Sp110,Hspa2 |
| 4.913e-03 | -5.32 | integrin complex | cellular component | GO:0008305 | 32 | 7 | 20747 | 1409 |
Itga9,Lyn,Itga4,Itgav,Itga5,Itgal,Itgb8 |
| 4.919e-03 | -5.31 | HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_DN | MSigDB lists | HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_DN | 15 | 5 | 15632 | 1249 |
Dyrk2,Ifnar1,Stat2,Pf4,Ptch1 |
| 4.919e-03 | -5.31 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | MSigDB lists | REACTOME_PLATELET_SENSITIZATION_BY_LDL | 15 | 5 | 15632 | 1249 |
Fgr,Ppp2r1b,Ppp2r5a,Lrp8,Pla2g4a |
| 4.919e-03 | -5.31 | GO_POSITIVE_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE | 15 | 5 | 15632 | 1249 |
Il12b,Il12rb1,Cd80,Ripk2,Hlx |
| 4.919e-03 | -5.31 | XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP | MSigDB lists | XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP | 15 | 5 | 15632 | 1249 |
Hdac1,Birc2,Nmi,Tnfsf10,Stat1 |
| 4.919e-03 | -5.31 | GHO_ATF5_TARGETS_DN | MSigDB lists | GHO_ATF5_TARGETS_DN | 15 | 5 | 15632 | 1249 |
Itga5,Trip13,Dusp1,Rnd3,Slc2a1 |
| 4.919e-03 | -5.31 | GO_MHC_CLASS_I_PROTEIN_BINDING | MSigDB lists | GO_MHC_CLASS_I_PROTEIN_BINDING | 15 | 5 | 15632 | 1249 |
Tap1,Tapbp,Pilra,Pilrb2,Pilrb1 |
| 4.919e-03 | -5.31 | ABE_VEGFA_TARGETS | MSigDB lists | ABE_VEGFA_TARGETS | 15 | 5 | 15632 | 1249 |
Ptgs2,Rcan1,Egr2,Slc4a7,Egr3 |
| 4.919e-03 | -5.31 | GO_NITRIC_OXIDE_METABOLIC_PROCESS | MSigDB lists | GO_NITRIC_OXIDE_METABOLIC_PROCESS | 15 | 5 | 15632 | 1249 |
Gch1,Arg2,Slc7a2,Nos2,Nqo1 |
| 4.919e-03 | -5.31 | PID_IL5_PATHWAY | MSigDB lists | PID_IL5_PATHWAY | 15 | 5 | 15632 | 1249 |
Stat5a,Jak2,Cish,Pim1,Lyn |
| 4.919e-03 | -5.31 | GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION | 15 | 5 | 15632 | 1249 |
Fgr,Nr4a3,Il4ra,Adora2b,Syk |
| 4.919e-03 | -5.31 | GO_POSITIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | 15 | 5 | 15632 | 1249 |
Traf2,Casp8,Jak2,Fas,Tnfsf10 |
| 4.919e-03 | -5.31 | GO_ACTIVATION_OF_NF_KAPPAB_INDUCING_KINASE_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_NF_KAPPAB_INDUCING_KINASE_ACTIVITY | 15 | 5 | 15632 | 1249 |
Traf2,Tnfsf15,Tlr6,Malt1,Tlr3 |
| 4.919e-03 | -5.31 | GO_NEGATIVE_REGULATION_OF_ANOIKIS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ANOIKIS | 15 | 5 | 15632 | 1249 |
Itga5,Src,Ptk2,Cav1,Notch1 |
| 4.924e-03 | -5.31 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent | biological process | GO:0002486 | 32 | 7 | 20694 | 1406 |
H2-T22,H2-Q6,H2-Q7,H2-Q4,H2-T24,H2-M2,H2-T10 |
| 4.924e-03 | -5.31 | regulation of oxidative stress-induced neuron death | biological process | GO:1903203 | 32 | 7 | 20694 | 1406 |
Slc7a11,Il10,Fzd1,Ncoa7,Nr4a3,Tlr6,Hif1a |
| 4.924e-03 | -5.31 | regulation of viral release from host cell | biological process | GO:1902186 | 32 | 7 | 20694 | 1406 |
Trim21,Trim26,Chmp4b,Pcx,Trim13,Trim56,Pml |
| 4.924e-03 | -5.31 | positive regulation of acute inflammatory response | biological process | GO:0002675 | 32 | 7 | 20694 | 1406 |
Ccl5,Ptgs2,Tnf,Il1b,C3,Fcgr1,Il6 |
| 4.940e-03 | -5.31 | GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_DN | MSigDB lists | GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_DN | 162 | 23 | 15632 | 1249 |
Psmb9,Rhbdf2,Dock4,Itgav,Phlpp1,Cycs,Stat3,Ctsc,Dbnl,Ddx58,Rnd1,Gmppb,Pml,Rab3ip,Plau,Ccnj,Ccdc25,Rasgrp1,Nfkbib,Tnip3,Lyn,Dgkh,Larp1 |
| 4.971e-03 | -5.30 | type I interferon receptor binding | molecular function | GO:0005132 | 24 | 6 | 20217 | 1400 |
Ifna6,Ifna4,Ifna2,Ifna5,Ifnb1,Ifna1 |
| 4.983e-03 | -5.30 | STEIN_ESRRA_TARGETS | MSigDB lists | STEIN_ESRRA_TARGETS | 463 | 53 | 15632 | 1249 |
Slc31a1,Inpp1,Asns,Higd1a,Rnaset2a,Gdf15,4930523C07Rik,Arid4a,Slc25a12,Scn1b,Slc2a6,Jmjd6,Rnf139,Daxx,Cd83,Rnf34,Slc16a3,Dusp1,Ccng2,Rhoq,Rab21,Cycs,Ier3,Mmp9,Prkar2b,Fam162a,Rnaset2b,Stard7,Ust,Fscn1,Gfpt1,Cflar,Rnf14,Hk1,Rap1gap2,Egln3,Slc39a14,Pdss1,Ampd3,St3gal5,Alas1,Trim14,Phip,Ciapin1,Aff1,Slc16a1,Plau,Rhof,Tmem184b,Ets2,Sod2,Mid1,Ctsc |
| 4.983e-03 | -5.30 | GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 463 | 53 | 15632 | 1249 |
Birc3,S100a8,Cav1,Cenpj,Slc9a1,Rictor,Ptk2,Tmod3,Lpar1,Tmem67,Fscn1,Whamm,Hcls1,Ezr,Sbds,Nlrc4,Cyfip1,Edn1,Prkce,Stap1,Triobp,Mid1,Nck1,Evl,Nek6,Tpx2,Cdk5r1,Sdc4,Cdc42ep2,Chmp4b,Mark2,Plek,Myadm,Plk2,Pdgfrb,Csf3,Vasp,Ptger4,Parp3,Cdc42ep4,Spire1,Clic4,Dync1h1,Phldb1,Swap70,Rgs14,Birc2,Gpsm2,Rhoq,Asap3,F11r,Icam1,Hck |
| 5.005e-03 | -5.30 | GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDC_DN | 181 | 25 | 15632 | 1249 |
Itga4,Upp1,Pilra,Cd38,Plagl2,Arid5a,Cited2,Prokr1,Slc39a4,Cp,Nqo1,B3gnt5,Hp,Slc31a1,Adrb2,Serpinb2,P4ha1,Cav1,Cacybp,Myo1b,Marco,Stxbp3,Slpi,Ccrl2,Rasgrp1 |
| 5.005e-03 | -5.30 | GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_UP | MSigDB lists | GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_UP | 181 | 25 | 15632 | 1249 |
Eno1,Tnf,Hivep2,Srm,Ggct,Ccdc86,Pnp2,Gbe1,Palld,Rras2,Lcp2,Txn1,Rcan1,Rcn1,Nsmaf,Ldha,Psmb6,Dusp5,Ripk2,Nfil3,Pgk1,Il1b,Polr2g,Cflar,Idi1 |
| 5.005e-03 | -5.30 | GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_UP | MSigDB lists | GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_UP | 181 | 25 | 15632 | 1249 |
Ppp1r15a,Sipa1l1,Dmwd,Isg20,Ccrl2,St3gal1,Serpinb9,Notch2,Agpat4,Mob3c,Axl,Ezr,Mrpl52,Il18bp,Chst11,Kdm5b,Samd9l,Phactr4,Pml,Egr1,Lif,Stxbp1,Gnb4,Spred1,Crim1 |
| 5.005e-03 | -5.30 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_DN | 181 | 25 | 15632 | 1249 |
Casp7,Endod1,Znrf1,Plat,Rgs1,Sp110,Hcar2,Card6,Akt3,Slc39a14,Zscan29,Mapkbp1,1600014C10Rik,Cd38,Zfp319,Src,Spsb1,N4bp1,Klhl25,Mtus1,Cd40,Stat3,Oaf,Fchsd2,Cpd |
| 5.005e-03 | -5.30 | GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP | 181 | 25 | 15632 | 1249 |
Gnb4,Etv5,Ccnd2,Gbe1,Sass6,Stat3,Mid1,Dek,Gfpt1,Jak2,Fscn1,Adam19,Irak2,Fam162a,Nfil3,Endod1,Pim1,Ak4,Mthfd2,Map3k8,Zeb1,Snx10,Eno2,Nfkb1,Ccne1 |
| 5.005e-03 | -5.30 | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_UP | 181 | 25 | 15632 | 1249 |
Cacnb3,Tapbpl,Xkr8,Kif5c,Il13ra1,Tax1bp1,Golga3,Procr,Etv3,P2ry14,Gbp3,Ier2,Samhd1,Klhl25,Mgat1,Tmem184b,Cited2,Gsdmd,Spsb1,Crbn,Slc7a11,Cox17,Lztfl1,Kremen1,Slc39a4 |
| 5.005e-03 | -5.30 | GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_UP | 181 | 25 | 15632 | 1249 |
Igf2bp2,Pgk1,Inpp1,Tnfsf10,Kcna3,Smox,Cd200,Stat4,Rnf19a,Gbp7,Ankib1,Ripk3,Klf7,Gbp2,Slc16a1,Sell,Nck1,Treml2,Rffl,Ly75,Cish,Arid5a,Klf3,Sod2,Insl6 |
| 5.005e-03 | -5.30 | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP | 181 | 25 | 15632 | 1249 |
Homer1,Dnaja1,Cd302,Hspa1a,Hsph1,Axl,Dusp1,Map3k6,Plekhf2,Cebpd,Arl4a,Pilra,Ahsa1,Cacybp,Ednrb,Akt3,Ube2l6,Alas1,Dnajb4,Dnaja2,Tmod3,Rcl1,Stip1,Il1rn,Clic4 |
| 5.046e-03 | -5.29 | Stat3 (signal transducer and activator of transcription 3) | protein interactions | 20848 | 29 | 8 | 7778 | 753 |
Jun,Stat1,Irf4,Stat2,Ociad1,Stat3,Jak2,Src |
| 5.060e-03 | -5.29 | GO_CORE_PROMOTER_BINDING | MSigDB lists | GO_CORE_PROMOTER_BINDING | 153 | 22 | 15632 | 1249 |
Nlrc5,Ifi213,Ifi209,Mndal,Ifi205,Irf7,Fos,Ifi208,Ifi211,Ifi203,Hdac1,Sirt1,Stat1,Ifi214,Nr4a3,Ifi204,Zfp281,Nfil3,Relb,Ifi207,Notch1,H3f3b |
| 5.060e-03 | -5.29 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_DN | 153 | 22 | 15632 | 1249 |
Rhou,Rapgef2,Itgb8,Ddit4,Bcl6,Ccl12,Tnfrsf1b,Junb,Ifit1bl1,Ifit1bl2,Il1b,Dnase1l3,Dusp16,Notch1,Hvcn1,Cd82,Gbp3,P2ry14,Cd74,Pim2,Palld,Oasl1 |
| 5.093e-03 | -5.28 | GO_TUBE_MORPHOGENESIS | MSigDB lists | GO_TUBE_MORPHOGENESIS | 319 | 39 | 15632 | 1249 |
Timeless,Csf1,Zeb1,Met,Fzd1,Vasp,Gja1,Mthfd1l,Lmo4,Ptch1,Clic4,Prkx,Sec24b,Lhx2,Sema4c,Nr4a3,Myc,Mmp14,Setdb2,Spry2,Tnc,Edn1,Acvrl1,Phactr4,Ift57,Acvr1,Kdm5b,Bcl2l11,Src,Pbx1,Bmp2,Sdc4,Apaf1,Notch1,Pml,Hhex,Hlx,Tulp3,Hif1a |
| 5.095e-03 | -5.28 | CERVERA_SDHB_TARGETS_1_UP | MSigDB lists | CERVERA_SDHB_TARGETS_1_UP | 99 | 16 | 15632 | 1249 |
Htra1,Edn1,Gpr68,Dusp4,Smpdl3b,Nod2,Inhba,Ifit2,Sgcb,Lhx2,Kif3c,Rab20,Il18,Pik3cd,Ubash3b,Cacnb3 |
| 5.095e-03 | -5.28 | WESTON_VEGFA_TARGETS | MSigDB lists | WESTON_VEGFA_TARGETS | 99 | 16 | 15632 | 1249 |
Vcan,Sat1,Pnp2,Gem,Pde4b,Nr4a1,Ccl12,Htr2b,Vcam1,Sdc4,Cd34,Kdr,Hcls1,Tnfsf10,Adora2b,Pim1 |
| 5.101e-03 | -5.28 | CTGAGCC_MIR24 | MSigDB lists | CTGAGCC_MIR24 | 210 | 28 | 15632 | 1249 |
Mmp14,Bcl2l11,Ccdc88b,Tab2,Plk3,Marcksl1,Apba1,Hap1,Inpp5b,Col11a2,Plod2,Dusp16,Dcbld2,Snn,Nfxl1,Plcl2,Adam19,Rap2c,Pim1,Acvr1b,Sema4a,Mafg,Arid5b,Ptger4,Kpna3,Mtmr14,Dyrk2,Pim2 |
| 5.115e-03 | -5.28 | Apelin signaling pathway | KEGG pathways | mmu04371 | 137 | 22 | 7931 | 713 |
Rras2,Pde3b,Serpine1,Gng4,Slc9a1,Sphk1,Prkce,Pik3r6,Nos2,Akt3,Gng12,Plat,Gng11,Jag1,Map2k1,Gnb4,Lipe,Klf2,Ccnd1,Itpr1,Egr1,Pik3r5 |
| 5.117e-03 | -5.28 | NEMO_N | interpro domains | IPR021063 | 2 | 2 | 19984 | 1430 |
Optn,Ikbkg |
| 5.117e-03 | -5.28 | Nmi/IFP35_dom | interpro domains | IPR009909 | 2 | 2 | 19984 | 1430 |
Ifi35,Nmi |
| 5.117e-03 | -5.28 | AHR/AHRR | interpro domains | IPR039091 | 2 | 2 | 19984 | 1430 |
Ahr,Ahrr |
| 5.117e-03 | -5.28 | Lamina-ass_polypeptide_CLAP1C | interpro domains | IPR008662 | 2 | 2 | 19984 | 1430 |
Tor1aip1,Tor1aip2 |
| 5.117e-03 | -5.28 | ABC_Tap-like | interpro domains | IPR013305 | 2 | 2 | 19984 | 1430 |
Tap1,Tap2 |
| 5.117e-03 | -5.28 | PUFD | interpro domains | IPR032365 | 2 | 2 | 19984 | 1430 |
Bcor,Bcorl1 |
| 5.117e-03 | -5.28 | HMGA | interpro domains | IPR000116 | 2 | 2 | 19984 | 1430 |
Hmga1,Hmga2 |
| 5.117e-03 | -5.28 | IL6/GCSF/MGF_CS | interpro domains | IPR030473 | 2 | 2 | 19984 | 1430 |
Csf3,Il6 |
| 5.117e-03 | -5.28 | Leukemia_IF/oncostatin | interpro domains | IPR001581 | 2 | 2 | 19984 | 1430 |
Lif,Osm |
| 5.117e-03 | -5.28 | Rib_rcpt_KP | interpro domains | IPR007794 | 2 | 2 | 19984 | 1430 |
Ktn1,Rrbp1 |
| 5.117e-03 | -5.28 | ADP-ribosyl_cyclase | interpro domains | IPR003193 | 2 | 2 | 19984 | 1430 |
Cd38,Bst1 |
| 5.117e-03 | -5.28 | Liprin-beta_SAM_rpt_2 | interpro domains | IPR037618 | 2 | 2 | 19984 | 1430 |
Ppfibp1,Ppfibp2 |
| 5.117e-03 | -5.28 | Interferon-induced_IFIT1 | interpro domains | IPR024121 | 2 | 2 | 19984 | 1430 |
Ifit1bl2,Ifit1bl1 |
| 5.117e-03 | -5.28 | Zalpha_dom | interpro domains | IPR042371 | 2 | 2 | 19984 | 1430 |
Adar,Zbp1 |
| 5.117e-03 | -5.28 | LAP1C-like_C_sf | interpro domains | IPR038599 | 2 | 2 | 19984 | 1430 |
Tor1aip2,Tor1aip1 |
| 5.117e-03 | -5.28 | TRC8_N_dom | interpro domains | IPR025754 | 2 | 2 | 19984 | 1430 |
Rnf139,Rnf145 |
| 5.117e-03 | -5.28 | DUF4569 | interpro domains | IPR027869 | 2 | 2 | 19984 | 1430 |
5430427O19Rik,Gm6377 |
| 5.117e-03 | -5.28 | Cop_transporter | interpro domains | IPR007274 | 2 | 2 | 19984 | 1430 |
Slc31a2,Slc31a1 |
| 5.117e-03 | -5.28 | TMEM176A/TMEM176B | interpro domains | IPR009281 | 2 | 2 | 19984 | 1430 |
Tmem176a,Tmem176b |
| 5.117e-03 | -5.28 | Prot_Pase1_reg-su15A/B_C | interpro domains | IPR019523 | 2 | 2 | 19984 | 1430 |
Ppp1r15a,Ppp1r15b |
| 5.117e-03 | -5.28 | Liprin-beta_SAM_rpt_1 | interpro domains | IPR037617 | 2 | 2 | 19984 | 1430 |
Ppfibp1,Ppfibp2 |
| 5.117e-03 | -5.28 | MARCKS | interpro domains | IPR002101 | 2 | 2 | 19984 | 1430 |
Marcksl1,Marcks |
| 5.117e-03 | -5.28 | BIRC2/BIRC3_UBA | interpro domains | IPR041933 | 2 | 2 | 19984 | 1430 |
Birc3,Birc2 |
| 5.117e-03 | -5.28 | Nmi/IFP35_N | interpro domains | IPR009938 | 2 | 2 | 19984 | 1430 |
Nmi,Ifi35 |
| 5.117e-03 | -5.28 | Interferon-induced_IFIT3 | interpro domains | IPR024122 | 2 | 2 | 19984 | 1430 |
Ifit3,Ifit3b |
| 5.117e-03 | -5.28 | IRF1/IRF2 | interpro domains | IPR017431 | 2 | 2 | 19984 | 1430 |
Irf2,Irf1 |
| 5.117e-03 | -5.28 | OGF_rcpt | interpro domains | IPR006757 | 2 | 2 | 19984 | 1430 |
Ogfr,Ogfrl1 |
| 5.117e-03 | -5.28 | IL-1_propep | interpro domains | IPR003502 | 2 | 2 | 19984 | 1430 |
Il1a,Il1b |
| 5.117e-03 | -5.28 | Leukemia_IF/oncostatin_CS | interpro domains | IPR019827 | 2 | 2 | 19984 | 1430 |
Lif,Osm |
| 5.117e-03 | -5.28 | TRAF_BIRC3-bd | interpro domains | IPR032070 | 2 | 2 | 19984 | 1430 |
Traf1,Traf2 |
| 5.117e-03 | -5.28 | PIK3R5/6 | interpro domains | IPR019522 | 2 | 2 | 19984 | 1430 |
Pik3r5,Pik3r6 |
| 5.117e-03 | -5.28 | VASP/EVL | interpro domains | IPR017354 | 2 | 2 | 19984 | 1430 |
Vasp,Evl |
| 5.117e-03 | -5.28 | PUFD_som_sf | interpro domains | IPR038227 | 2 | 2 | 19984 | 1430 |
Bcor,Bcorl1 |
| 5.117e-03 | -5.28 | OGFr | interpro domains | IPR039574 | 2 | 2 | 19984 | 1430 |
Ogfrl1,Ogfr |
| 5.117e-03 | -5.28 | IL-6/GCSF/MGF | interpro domains | IPR030474 | 2 | 2 | 19984 | 1430 |
Il6,Csf3 |
| 5.117e-03 | -5.28 | Liprin-beta_SAM_rpt_3 | interpro domains | IPR037619 | 2 | 2 | 19984 | 1430 |
Ppfibp2,Ppfibp1 |
| 5.126e-03 | -5.27 | 2-oxoglutarate-dependent dioxygenase activity | molecular function | GO:0016706 | 48 | 9 | 20217 | 1400 |
Jmjd6,Kdm4a,Plod2,Tet2,Egln3,Plod3,P4ha2,P4ha1,Phyh |
| 5.132e-03 | -5.27 | organic substance catabolic process | biological process | GO:1901575 | 1405 | 120 | 20694 | 1406 |
Uchl1,Zhx2,Hk1,Pfkl,Tmem67,Cnot4,Lipg,Bnip3,Psmb6,Oas2,Tha1,Psmb10,Inpp5b,Rffl,Magohb,Smox,Plaat3,Eno2,Pml,Casp8,Ago3,Pla2g4a,Uba7,Asah2,Armc8,Bfar,Rnf19a,Noct,Adhfe1,Keap1,Usp18,Helz2,Hk2,Cemip2,Il4i1,Trim13,Polr2g,Tet2,Isg15,Mdm2,Arel1,Sirt1,Mgat1,Ankib1,Atm,Tent4a,Upp1,Ddhd1,Tpi1,Ubr4,Isg20,Samhd1,Ctsc,Sat1,Ube2l6,Slfn8,Fbxo4,Ldha,Dnajb2,Pla2g7,Esd,Tent2,Birc2,Xrn1,Rnf19b,Cop1,Gda,Kmo,Enpp4,Dtx3l,Pde5a,Dcp1a,Lnpep,Zfp36,Pnpt1,Hdc,Rnf34,Mmp13,Apobec3,Znrf3,Usp42,Inpp1,Dio2,Psmb8,Cnp,Gtpbp2,Arrdc4,Dcp2,Psmb9,Klhl25,Pgk1,Tnfaip3,Hmox1,Znrf1,Crbn,Gsta3,Lipe,Chmp4b,Dnase1l3,Zc3h12a,Spsb1,Rnf139,Hk3,Phyh,Rnf14,Psma6,Gpd2,Nos2,Gpc1,Usp25,Traf2,Usp12,Arg2,Smg7,Ldlr,Rnaset2a,Aoah,Smpdl3b,Tut7,Peli1 |
| 5.164e-03 | -5.27 | GO_POSITIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY | 42 | 9 | 15632 | 1249 |
Gch1,Tnf,Hif1a,Nod1,Edn1,Htr2b,Il1b,Ripk3,Nod2 |
| 5.164e-03 | -5.27 | LEE_AGING_MUSCLE_UP | MSigDB lists | LEE_AGING_MUSCLE_UP | 42 | 9 | 15632 | 1249 |
Stard7,Mecp2,Htra1,Rab21,Fos,Plagl1,Usp53,Atf3,Nampt |
| 5.164e-03 | -5.27 | GO_REGULATION_OF_INSULIN_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_INSULIN_RECEPTOR_SIGNALING_PATHWAY | 42 | 9 | 15632 | 1249 |
Cish,Il1b,Ncoa5,Sirt1,Socs3,Src,Ptpn2,Socs1,Pid1 |
| 5.164e-03 | -5.27 | GO_PROTEIN_TYROSINE_SERINE_THREONINE_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_PROTEIN_TYROSINE_SERINE_THREONINE_PHOSPHATASE_ACTIVITY | 42 | 9 | 15632 | 1249 |
Dusp1,Dusp5,Dusp6,Dusp16,Dusp14,Dusp4,Dusp28,Dusp2,Dusp8 |
| 5.164e-03 | -5.27 | GO_MODIFICATION_BY_SYMBIONT_OF_HOST_MORPHOLOGY_OR_PHYSIOLOGY | MSigDB lists | GO_MODIFICATION_BY_SYMBIONT_OF_HOST_MORPHOLOGY_OR_PHYSIOLOGY | 42 | 9 | 15632 | 1249 |
Zc3hav1,Tnip1,Serpinb9,Casp8,Itgav,Bcl2l11,Zc3h12a,Eif2ak2,Kpna3 |
| 5.173e-03 | -5.26 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_DN | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_DN | 172 | 24 | 15632 | 1249 |
Bcl2a1b,Txnrd1,Insl6,Fgl2,Lztfl1,Bcl2a1d,Minpp1,Casp3,Phgdh,Rai14,Usp25,Batf,Il10,Casp4,Smpdl3b,Egln3,Cxcl2,Psme2,Rab20,Denr,Pmepa1,Glrx,Acsl5,Bcl2a1a |
| 5.173e-03 | -5.26 | GSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_UP | MSigDB lists | GSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_UP | 172 | 24 | 15632 | 1249 |
Slc15a3,Slc39a4,Ccr3,Spry2,Zyx,Rhbdf2,Slc28a2,Adar,Ifih1,Fgr,Traf1,Palld,Nmi,Irf7,Ifit3,Gch1,Rabgef1,Gsta3,Ifit3b,Lox,Slc43a3,Kcna3,Stat1,Zc3h12a |
| 5.177e-03 | -5.26 | GSE339_CD4POS_VS_CD4CD8DN_DC_UP | MSigDB lists | GSE339_CD4POS_VS_CD4CD8DN_DC_UP | 191 | 26 | 15632 | 1249 |
Stat1,Il18,Serpinb2,Tnip1,Slfn3,Trafd1,Acp2,Atp6v1d,Slfn4,Lcp2,Stxbp3,Pdgfb,Procr,Fabp7,Zeb1,Trim21,Nr1h3,Ccnd2,Usp18,F11r,Dnase1l3,Gbp2,Agrn,Tnf,Spn,Pde1b |
| 5.177e-03 | -5.26 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_DN | 191 | 26 | 15632 | 1249 |
Cdkn2d,Hlx,Gbp3,Il4ra,Prnp,Myd88,Gbp2,Angpt1,Cx3cr1,Csf3r,Cish,Il6,Ly75,Cebpd,Gadd45g,Il18bp,Ncoa5,Il13ra1,Larp1,Lpar1,Ccl4,Il1rn,Dusp16,Fam162a,Ppp4r2,Procr |
| 5.187e-03 | -5.26 | NEMO | pfam domains | PF11577 | 2 | 2 | 18711 | 1348 |
Ikbkg,Optn |
| 5.187e-03 | -5.26 | DUF4569 | pfam domains | PF15133 | 2 | 2 | 18711 | 1348 |
Gm6377,5430427O19Rik |
| 5.187e-03 | -5.26 | Ctr | pfam domains | PF04145 | 2 | 2 | 18711 | 1348 |
Slc31a1,Slc31a2 |
| 5.187e-03 | -5.26 | NID | pfam domains | PF07292 | 2 | 2 | 18711 | 1348 |
Nmi,Ifi35 |
| 5.187e-03 | -5.26 | 2OG-FeII_Oxy | pfam domains | PF03171 | 2 | 2 | 18711 | 1348 |
Plod2,Plod3 |
| 5.187e-03 | -5.26 | PP1c_bdg | pfam domains | PF10488 | 2 | 2 | 18711 | 1348 |
Ppp1r15b,Ppp1r15a |
| 5.187e-03 | -5.26 | LIF_OSM | pfam domains | PF01291 | 2 | 2 | 18711 | 1348 |
Lif,Osm |
| 5.187e-03 | -5.26 | z-alpha | pfam domains | PF02295 | 2 | 2 | 18711 | 1348 |
Zbp1,Adar |
| 5.187e-03 | -5.26 | LAP1C | pfam domains | PF05609 | 2 | 2 | 18711 | 1348 |
Tor1aip2,Tor1aip1 |
| 5.187e-03 | -5.26 | Rib_hydrolayse | pfam domains | PF02267 | 2 | 2 | 18711 | 1348 |
Bst1,Cd38 |
| 5.187e-03 | -5.26 | IFP_35_N | pfam domains | PF07334 | 2 | 2 | 18711 | 1348 |
Ifi35,Nmi |
| 5.187e-03 | -5.26 | Rib_recp_KP_reg | pfam domains | PF05104 | 2 | 2 | 18711 | 1348 |
Ktn1,Rrbp1 |
| 5.187e-03 | -5.26 | PI3K_1B_p101 | pfam domains | PF10486 | 2 | 2 | 18711 | 1348 |
Pik3r6,Pik3r5 |
| 5.187e-03 | -5.26 | MARCKS | pfam domains | PF02063 | 2 | 2 | 18711 | 1348 |
Marcksl1,Marcks |
| 5.187e-03 | -5.26 | TRAF_BIRC3_bd | pfam domains | PF16673 | 2 | 2 | 18711 | 1348 |
Traf1,Traf2 |
| 5.187e-03 | -5.26 | OGFr_N | pfam domains | PF04664 | 2 | 2 | 18711 | 1348 |
Ogfr,Ogfrl1 |
| 5.187e-03 | -5.26 | TRC8_N | pfam domains | PF13705 | 2 | 2 | 18711 | 1348 |
Rnf145,Rnf139 |
| 5.187e-03 | -5.26 | IL1_propep | pfam domains | PF02394 | 2 | 2 | 18711 | 1348 |
Il1a,Il1b |
| 5.187e-03 | -5.26 | PUFD | pfam domains | PF16553 | 2 | 2 | 18711 | 1348 |
Bcorl1,Bcor |
| 5.198e-03 | -5.26 | viral life cycle | biological process | GO:0019058 | 86 | 13 | 20694 | 1406 |
Nectin2,Chmp4b,Axl,Cd55,Pvr,Nectin4,Clec5a,Cd300lf,Icam1,Cav1,Tnfrsf14,Pcx,Itgav |
| 5.198e-03 | -5.26 | vasculogenesis | biological process | GO:0001570 | 86 | 13 | 20694 | 1406 |
Cited2,Spred1,Kdr,Cav1,Tiparp,Pdgfrb,Junb,Angpt1,Ptk2,Itgb8,Ptprj,Notch1,Hhex |
| 5.204e-03 | -5.26 | Sqstm1 (sequestosome 1) | protein interactions | 18412 | 48 | 11 | 7778 | 753 |
Optn,Tax1bp1,Klf3,Keap1,Gja1,Casp8,Sqstm1,Gbp2,Klf2,Gnb4,Trim30a |
| 5.206e-03 | -5.26 | regulation of smooth muscle contraction | biological process | GO:0006940 | 67 | 11 | 20694 | 1406 |
Ptgs2,Dock4,Map2k1,Adora2b,Cav1,Calcrl,Edn1,Ptafr,Sphk1,Ptger4,Adrb2 |
| 5.211e-03 | -5.26 | GO_UBIQUITIN_LIKE_PROTEIN_BINDING | MSigDB lists | GO_UBIQUITIN_LIKE_PROTEIN_BINDING | 108 | 17 | 15632 | 1249 |
Optn,Ubtd2,Ube2l6,Dcun1d3,Rnf31,Ikbkg,Sqstm1,Tnfaip3,Dnajb2,Ikbke,Tab2,Tnip3,Uchl1,Dyrk2,Usp25,Pml,Parp10 |
| 5.217e-03 | -5.26 | Platelet sensitization by LDL | REACTOME pathways | R-MMU-432142 | 9 | 4 | 8608 | 757 |
Lrp8,Gna15,Pla2g4a,Fgr |
| 5.218e-03 | -5.26 | regulation of erythrocyte differentiation | biological process | GO:0045646 | 49 | 9 | 20694 | 1406 |
Isg15,Stat5a,Lyn,Inhba,Zfp36,Hif1a,Stat3,Acvr1b,Stat1 |
| 5.218e-03 | -5.26 | activation of MAPKK activity | biological process | GO:0000186 | 49 | 9 | 20694 | 1406 |
Map3k8,Ripk2,Gadd45b,Eif2ak2,Mapkbp1,Gadd45g,Map3k6,Mlkl,Jak2 |
| 5.221e-03 | -5.26 | organophosphate metabolic process | biological process | GO:0019637 | 706 | 66 | 20694 | 1406 |
Nt5c3,Kmo,Lpcat2,Pde5a,Pdgfrb,Papss2,Pla2g7,Hk1,Sgms2,Socs7,Dgkh,Pfkl,Hmgcs1,Rhoq,Cish,Eno2,Nampt,Cnp,Pikfyve,Pla2g4a,Acpp,Etnk1,Pigv,Pgs1,Cept1,Gk,Inpp5b,Socs1,Mecp2,Plpp3,Agpat4,Plaat3,Socs3,Inpp1,Gfpt1,Mppe1,Acsl5,Mocs1,Plcl2,Hk3,Pgk1,Plpp1,Hk2,Cmpk2,Tpi1,Samhd1,Ampd3,Dgka,Idi1,Pik3cd,Smpdl3b,Grk3,Itpkc,Dck,Plek,Plscr1,Oasl2,Gpd2,Pfkfb3,Atm,Upp1,Ak4,Oas1a,Acsl1,Ptafr,Pgap2 |
| 5.248e-03 | -5.25 | nuclear outer membrane-endoplasmic reticulum membrane network | cellular component | GO:0042175 | 532 | 52 | 20747 | 1409 |
Plpp3,Irgm2,Cept1,Rab10,Ch25h,Rnf139,Mtdh,Dst,Pigv,Igtp,Rtn1,Lnpk,Tapbp,Dnajb2,Ero1l,Rsad2,Irgm1,Gramd1a,Rrbp1,Tgtp2,Itpr1,Pgap2,Trim13,Iigp1,H2-Q4,Tmem67,9930111J21Rik1,Zc3h12a,Gm12185,Gm4841,Tap1,Vrk2,Rab19,F830016B08Rik,H2-Q7,Tmem178,Pml,Pnpt1,Gm4951,Rhbdf2,Slc37a3,Gm5431,Tmtc2,Traf2,Syne2,Dhrs9,Sgms2,Ext1,H2-Q6,Tap2,Ifi47,Tgtp1 |
| 5.265e-03 | -5.25 | BROWN_MYELOID_CELL_DEVELOPMENT_DN | MSigDB lists | BROWN_MYELOID_CELL_DEVELOPMENT_DN | 117 | 18 | 15632 | 1249 |
Pcx,Spint2,Slc7a5,H2-Aa,Fut8,Parp8,Slc7a8,Hsph1,Psat1,Wdr43,Rcl1,Slc16a1,Osbpl3,Papss2,St7,Tmtc2,Odc1,H2-Ab1 |
| 5.265e-03 | -5.25 | GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | 117 | 18 | 15632 | 1249 |
Zeb1,S1pr2,4932438A13Rik,Ccnd1,Errfi1,Acvrl1,Maff,Tnf,Cav1,Ptch1,Kitl,Prkx,Notch1,Keap1,Il1b,Lif,Stat1,Mafg |
| 5.269e-03 | -5.25 | GO_HEPATICOBILIARY_SYSTEM_DEVELOPMENT | MSigDB lists | GO_HEPATICOBILIARY_SYSTEM_DEVELOPMENT | 126 | 19 | 15632 | 1249 |
Ccne1,Ass1,Jarid2,Jun,Cited2,Tet2,Asns,Psmb9,Cp,Ccnd1,Hlx,Fas,Hhex,Hmgcs1,Adrb2,Arid5b,Ak4,Rpgrip1l,Notch1 |
| 5.274e-03 | -5.25 | Interleukin-2 signaling | REACTOME pathways | R-MMU-451927 | 228 | 32 | 8608 | 757 |
Psma6,Psme2,Psmd10,Psmb8,Met,Ptk2,Psmb10,Dusp6,Psmb6,Dusp5,Psme1,Psmb9,Rasgrp1,Stat5a,Rapgef2,Pik3cd,Src,Irs2,Ppp2r5a,Lgals9,Psme2b,Angpt1,Pdgfb,Kitl,Spred1,Map2k1,Jak2,Syk,Ppp2r1b,Pdgfrb,Il2rg,Ksr1 |
| 5.294e-03 | -5.24 | negative regulation of protein binding | biological process | GO:0032091 | 106 | 15 | 20694 | 1406 |
Il10,Pim2,Myc,Itga4,Adrb2,Actb,Mitd1,Plscr1,Met,Cav1,Dnajb2,Ifit2,Mecp2,Slpi,Pdgfb |
| 5.299e-03 | -5.24 | REL_2 | prosite domains | PS50254 | 10 | 4 | 13278 | 1037 |
Rel,Nfkb1,Nfkb2,Relb |
| 5.300e-03 | -5.24 | Syndecan interactions | REACTOME pathways | R-MMU-3000170 | 14 | 5 | 8608 | 757 |
Sdc2,Itgav,Sdc4,Tnc,Sdc1 |
| 5.304e-03 | -5.24 | vacuole | cellular component | GO:0005773 | 520 | 51 | 20747 | 1409 |
Clcn7,Il1b,Acpp,Cd74,Acp5,Calcrl,Rubcnl,Gja1,Sqstm1,Rnf19b,Cst7,Tnfaip3,Abcc1,Wdr59,Rnaset2b,Zc3hav1,Slc49a4,Mcoln2,Cd164,Ldlr,H2-Aa,Mmp13,Mt1,Pdgfrb,Hck,Rab9,Slc15a3,Hap1,Tlr9,Treml4,Ifnar1,Milr1,Slc30a4,Snx2,Ctsc,Src,Ass1,Slc48a1,Dram1,P2ry2,Irgm1,Trip10,Srgn,Rnaset2a,Dtx3l,Slc29a3,Acp2,Il4i1,H2-Eb1,Cd34,Znrf1 |
| 5.306e-03 | -5.24 | negative regulation of muscle cell apoptotic process | biological process | GO:0010656 | 58 | 10 | 20694 | 1406 |
Zc3h12a,Jak2,Edn1,Sirt1,Igf1r,Nupr1,Hmox1,Trip10,Cav1,Cflar |
| 5.329e-03 | -5.23 | GO_OUTER_MEMBRANE | MSigDB lists | GO_OUTER_MEMBRANE | 163 | 23 | 15632 | 1249 |
Bnip3,Slc44a1,Bcl2a1d,Rsad2,Rab32,Bcl2l11,Bcl2a1b,Ass1,Tspo,Prnp,Kmo,Mul1,Syne2,Hk2,Gja1,Hk1,Cnp,Ppp1r15a,Casp8,Bcl2a1a,Acsl5,Snn,Acsl1 |
| 5.329e-03 | -5.23 | GSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_UP | MSigDB lists | GSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_UP | 163 | 23 | 15632 | 1249 |
Psme2,Rhou,Ednrb,Fmnl2,Stat1,Rtn1,Pcgf5,Max,Gpd2,Ier3,Gpr85,Fam111a,Usp42,Nr3c1,Optn,Ddhd1,Ets2,Psmb9,Bmp2,Tnfaip3,Psme1,Pikfyve,Fam133b |
| 5.336e-03 | -5.23 | TGANTCA_AP1_C | MSigDB lists | TGANTCA_AP1_C | 1031 | 105 | 15632 | 1249 |
Il10,Lnpep,Eno2,Procr,Akt3,Itpkc,Stat1,Gfi1,Agpat4,Hcls1,Dock4,Znfx1,Cyfip1,Map3k6,Cxcl14,Il6,Angpt1,Mark2,Pfkfb3,Plau,Igsf8,Sipa1l1,Tuba4a,Snx10,Slc7a8,Dgka,Stx11,Csf3,Pim1,Thbs1,Serpinb2,Il1rn,Eno1,Acpp,Cst7,N4bp1,Dync1h1,Stk40,Mdm2,Dennd1b,Pde1b,Rhoq,Rhoc,Clcn5,Bmp2,Adap2,Lmo4,Usp12,Slc9a1,Isg20,Trib1,Rnf145,Tnip3,Dtx2,Mmp9,Cdkn1a,H3f3b,Col27a1,Jak2,Hmga1,Ass1,Sqstm1,Gadd45b,Dtnb,Gadd45g,Rin2,S1pr2,Cept1,Tor1aip2,Bnip3,Gpr141,Nek6,Dusp14,Olr1,Spred1,Hk3,Il27,Pdgfrb,Tor1aip1,Ppp1r15a,Brd2,Gja1,Igsf9,Vasp,Vasn,Mmp13,Nrp2,Reps1,Rcan1,Rtn1,Ppp2r2a,Gtpbp2,Mecp2,Tlk2,Sat1,Tab2,Slc39a13,Csrnp1,Prrg4,Prdm1,Tsku,Etv5,Rgs3,Rnf34,Sgk3 |
| 5.348e-03 | -5.23 | Regulation of mRNA stability by proteins that bind AU-rich elements | REACTOME pathways | R-MMU-450531 | 83 | 15 | 8608 | 757 |
Psmb8,Psmb10,Psme2,Psma6,Hspa1b,Psmd10,Psme2b,Dcp1a,Psmb9,Mapkapk2,Psmb6,Xrn1,Dcp2,Psme1,Anp32a |
| 5.351e-03 | -5.23 | CREB_Q4 | MSigDB lists | CREB_Q4 | 240 | 31 | 15632 | 1249 |
Kcnj2,Ift57,Dusp1,Slc25a37,Rbbp8,Ankrd17,Zmynd15,Fos,Rbms2,Tle3,Relb,Atf3,Hhex,Noc4l,Maff,Nfkbid,Jag1,G3bp2,Psmb8,Gem,Fosb,Ppp1r15a,Ppp2r2a,Pkp4,Ldha,Slc31a1,Egr3,Sema4c,Nr4a3,Trib1,Rcan1 |
| 5.353e-03 | -5.23 | maintenance of location | biological process | GO:0051235 | 169 | 21 | 20694 | 1406 |
Nfkbia,Morc3,Lcn2,Lgals9,Gpsm2,Pml,Il1b,Txn1,4932438A13Rik,Nfkbib,Hk2,Tspo,Cav1,Syne2,Tmsb10,Stat5a,Tnf,Srgn,Hk1,Psmd10,Keap1 |
| 5.353e-03 | -5.23 | placenta development | biological process | GO:0001890 | 169 | 21 | 20694 | 1406 |
Prdm1,Itga4,Junb,Met,Fzd5,Il10,Map2k1,Pla2g4a,Cited2,Lif,Pdgfb,Socs3,Hif1a,Htra1,Birc2,Spint2,Vcam1,Itgav,Serpine1,Notch2,Ptgs2 |
| 5.356e-03 | -5.23 | positive regulation of toll-like receptor 9 signaling pathway | biological process | GO:0034165 | 6 | 3 | 20694 | 1406 |
Rsad2,Tlr9,Treml4 |
| 5.356e-03 | -5.23 | positive regulation of miRNA metabolic process | biological process | GO:2000630 | 6 | 3 | 20694 | 1406 |
Nfkb1,Pnpt1,Zc3h12a |
| 5.356e-03 | -5.23 | positive regulation of apoptotic cell clearance | biological process | GO:2000427 | 6 | 3 | 20694 | 1406 |
Cd300lf,C3,Ccl2 |
| 5.356e-03 | -5.23 | regulation of macrophage inflammatory protein 1 alpha production | biological process | GO:0071640 | 6 | 3 | 20694 | 1406 |
Mcoln2,Arg2,Mefv |
| 5.356e-03 | -5.23 | regulation of adiponectin secretion | biological process | GO:0070163 | 6 | 3 | 20694 | 1406 |
Rab11fip1,Il1b,Hcar2 |
| 5.356e-03 | -5.23 | positive regulation of interleukin-18 production | biological process | GO:0032741 | 6 | 3 | 20694 | 1406 |
Tlr2,Tnf,Tlr9 |
| 5.356e-03 | -5.23 | regulation of T-helper 1 cell cytokine production | biological process | GO:2000554 | 6 | 3 | 20694 | 1406 |
Il1b,Arid5a,Il18 |
| 5.356e-03 | -5.23 | positive regulation of autophagosome maturation | biological process | GO:1901098 | 6 | 3 | 20694 | 1406 |
Irgm1,Irgm2,Adrb2 |
| 5.356e-03 | -5.23 | cellular response to interleukin-18 | biological process | GO:0071351 | 6 | 3 | 20694 | 1406 |
Il18,Il18rap,Pdgfb |
| 5.356e-03 | -5.23 | regulation of long-chain fatty acid import across plasma membrane | biological process | GO:0010746 | 6 | 3 | 20694 | 1406 |
Thbs1,Irs2,Acsl5 |
| 5.356e-03 | -5.23 | regulation of I-kappaB phosphorylation | biological process | GO:1903719 | 6 | 3 | 20694 | 1406 |
Traf2,Cx3cl1,Cx3cr1 |
| 5.356e-03 | -5.23 | necroptotic signaling pathway | biological process | GO:0097527 | 6 | 3 | 20694 | 1406 |
Tnf,Fas,Tlr3 |
| 5.356e-03 | -5.23 | regulation of MDA-5 signaling pathway | biological process | GO:0039533 | 6 | 3 | 20694 | 1406 |
Dhx58,Ddx60,Ankrd17 |
| 5.356e-03 | -5.23 | negative regulation of chronic inflammatory response | biological process | GO:0002677 | 6 | 3 | 20694 | 1406 |
Tnfaip3,Cx3cr1,Il10 |
| 5.356e-03 | -5.23 | positive regulation of T-helper 1 cell cytokine production | biological process | GO:2000556 | 6 | 3 | 20694 | 1406 |
Il18,Arid5a,Il1b |
| 5.356e-03 | -5.23 | tumor necrosis factor production | biological process | GO:0032640 | 6 | 3 | 20694 | 1406 |
Tlr2,Tlr9,Azi2 |
| 5.356e-03 | -5.23 | positive regulation of dendritic cell antigen processing and presentation | biological process | GO:0002606 | 6 | 3 | 20694 | 1406 |
Nod2,Cd74,Nod1 |
| 5.356e-03 | -5.23 | regulation of interleukin-1-mediated signaling pathway | biological process | GO:2000659 | 6 | 3 | 20694 | 1406 |
Il1rn,Il6,Vrk2 |
| 5.356e-03 | -5.23 | positive regulation of necrotic cell death | biological process | GO:0010940 | 6 | 3 | 20694 | 1406 |
Tspo,Bnip3,Ripk3 |
| 5.356e-03 | -5.23 | positive regulation of interleukin-10 secretion | biological process | GO:2001181 | 6 | 3 | 20694 | 1406 |
Ptger4,Lgals9,Cd274 |
| 5.356e-03 | -5.23 | negative regulation of T-helper 2 cell differentiation | biological process | GO:0045629 | 6 | 3 | 20694 | 1406 |
Hlx,Bcl6,Irf1 |
| 5.356e-03 | -5.23 | interleukin-15-mediated signaling pathway | biological process | GO:0035723 | 6 | 3 | 20694 | 1406 |
Il15,Il2rg,Il15ra |
| 5.356e-03 | -5.23 | positive regulation of platelet activation | biological process | GO:0010572 | 6 | 3 | 20694 | 1406 |
Pdpn,Ptprj,Plek |
| 5.356e-03 | -5.23 | cellular response to interleukin-15 | biological process | GO:0071350 | 6 | 3 | 20694 | 1406 |
Il2rg,Il15ra,Il15 |
| 5.356e-03 | -5.23 | B-1 B cell differentiation | biological process | GO:0001923 | 6 | 3 | 20694 | 1406 |
Plcl2,Slamf8,Malt1 |
| 5.356e-03 | -5.23 | inflammatory cell apoptotic process | biological process | GO:0006925 | 6 | 3 | 20694 | 1406 |
Fas,Hcar2,Il6 |
| 5.356e-03 | -5.23 | negative regulation of syncytium formation by plasma membrane fusion | biological process | GO:0034242 | 6 | 3 | 20694 | 1406 |
Cflar,Cxcl10,Stat1 |
| 5.366e-03 | -5.23 | regulation of protein polymerization | biological process | GO:0032271 | 213 | 25 | 20694 | 1406 |
Rac3,Gda,Dbnl,Myadm,Icam1,Prkce,Tlr2,Spire1,Tmsb10,Carmil1,Cav1,Rictor,Whamm,Csf3,Cdc42ep2,Cdc42ep4,Met,Nck1,Evl,Hcls1,Mecp2,Cyfip1,Tmod3,Vasp,Fchsd2 |
| 5.374e-03 | -5.23 | GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_DN | MSigDB lists | GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_DN | 182 | 25 | 15632 | 1249 |
Atp11a,Arrdc4,Rars,Nek6,Egr1,Extl2,Ttc39c,Tiparp,Spryd7,Gpr68,Rsad2,Setdb2,Slc43a3,Sema4a,Gpd2,Ptprj,Lacc1,Il1rn,Inpp1,Ptch1,Rgl1,Ahrr,Rhou,Ddit4,Btg2 |
| 5.374e-03 | -5.23 | GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_UP | MSigDB lists | GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_UP | 182 | 25 | 15632 | 1249 |
Cyfip1,Dse,Cd40,Slc2a1,Ifit2,Casp1,Ctsc,Tbc1d1,Irgm2,Kmo,Hlx,Irf2,Tmem176b,Bcor,Rnf139,Rbl1,Cep350,Tmem26,Aida,Cdc42ep4,Azi2,Casp7,Tlr3,Socs3,Tax1bp1 |
| 5.374e-03 | -5.23 | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_DN | 182 | 25 | 15632 | 1249 |
Rhoc,F11r,Socs1,Magohb,Hlx,Kremen1,Hdac1,Psma6,Gpr84,Cp,Slc44a1,Mrpl52,Gpsm2,Slc7a11,Srm,Stard7,Trem1,Tnip1,Acvr1b,Il18,Cxcl2,Tlr1,Gna15,S100a8,Slc13a3 |
| 5.374e-03 | -5.23 | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | 182 | 25 | 15632 | 1249 |
Hopx,Slfn4,Nampt,Syne2,Pou2f2,Stat4,Ep400,Ociad1,Rcn1,Ripk2,Ptger4,Hmgcs1,Glrx,Slfn9,Slfn3,Homer1,Swap70,Psmd10,Tspan3,Nr4a1,Dbnl,Ppp2r5a,Slfn8,Mcoln2,Rars |
| 5.374e-03 | -5.23 | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TREG_DN | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TREG_DN | 182 | 25 | 15632 | 1249 |
Inpp1,Ikbke,Aida,Chic2,4930453N24Rik,Azi2,Ptger4,Stat1,Gpr132,Lgals9,Fubp1,Mdfic,Hinfp,1600014C10Rik,Tab2,Usp18,Socs1,Fas,Tlr6,Hdac1,Triobp,Irgm2,Parp14,Stap1,Gramd1a |
| 5.374e-03 | -5.23 | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 182 | 25 | 15632 | 1249 |
Cd83,Mdfic,Rbl1,Prpf4,Daxx,Cst7,Tnf,Trip10,Tiparp,Cd40,Pnp2,Top3a,Cnot4,Ifrd1,Trafd1,Brd2,Gdf15,Ccne1,Rnf14,Psmb8,Itgal,Gna15,Ubr4,Inpp5b,Trim21 |
| 5.374e-03 | -5.23 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP | 182 | 25 | 15632 | 1249 |
Atf3,Hif1a,Mvp,Tnfaip3,Gadd45b,Nfkbia,Jun,1110038F14Rik,Nfkbie,Arhgap26,Dusp5,Dnaja2,Rnf19b,Fam53c,Irf1,Nfkb2,Rap2c,Junb,Tor3a,Lap3,Tap2,Ddit4,Cd69,Maff,G3bp2 |
| 5.374e-03 | -5.23 | GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_DN | MSigDB lists | GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_DN | 182 | 25 | 15632 | 1249 |
Trib1,Gfpt1,Clic4,Rel,Rrs1,Dusp6,Rnf14,Hivep3,Wars,Spint2,Trip13,Pgm1,Magohb,Egr1,Lrp8,Plagl2,Slc16a1,Homer1,Nfkbia,Tnf,Srm,Hspa2,Phgdh,Fut8,Ccdc86 |
| 5.374e-03 | -5.23 | GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_UP | MSigDB lists | GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_UP | 182 | 25 | 15632 | 1249 |
Hcls1,Acp2,Plaur,Pik3cd,Clec4d,Pou2f2,Rgl1,Igsf8,Col11a2,Fcgr1,Batf,Hck,Tlr6,Pml,Mthfr,Hlx,Abr,Egr2,Edn1,Abcc5,Plod3,Ccl12,Axl,Csf3r,Znfx1 |
| 5.374e-03 | -5.23 | GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_DN | 182 | 25 | 15632 | 1249 |
Shisa3,Max,Sp110,Ust,Rgs1,Nfkb2,Col27a1,Dach1,Snx10,Smpdl3b,Icosl,H2-Q7,Rhoc,Mdfic,Olr1,Rgs3,Slamf7,Rhbdf2,P2ry12,H2-Q6,Casp1,Eif2ak2,H2-Q4,Fcgr2b,Ccr3 |
| 5.374e-03 | -5.23 | GSE15930_STIM_VS_STIM_AND_IFNAB_24H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_24H_CD8_T_CELL_DN | 182 | 25 | 15632 | 1249 |
Ccl4,Pcdh7,Dek,Xcr1,Ier3,Ifit3b,Pstpip2,Snx2,Csrp1,Fosb,Ifit3,Lgals9,Plau,Myo10,Cdkn2d,Mthfr,Slc30a1,Tulp3,Il1a,Ctsc,Ccnd1,Itgav,Ifit2,Eno1,Swap70 |
| 5.374e-03 | -5.23 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_UP | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_UP | 182 | 25 | 15632 | 1249 |
Cd86,Gna15,Hopx,Gbp7,Gem,Tshz1,Myadm,Il12rb1,Eef1e1,Rap1gap2,Pdss1,Smc5,Il15ra,Dcbld2,Stip1,Prkar2b,Osbpl3,Irak2,Ust,Swap70,Pik3r5,Mdm2,Gbp3,Samhd1,Mdfic |
| 5.386e-03 | -5.22 | Programmed Cell Death | REACTOME pathways | R-MMU-5357801 | 99 | 17 | 8608 | 757 |
Apaf1,Pmaip1,Bcl2l11,Casp3,Tnfsf10,Birc2,Mlkl,Casp7,Traf2,Ripk3,Ptk2,Birc3,Dbnl,Fas,Cflar,Cycs,Casp8 |
| 5.390e-03 | -5.22 | protein phosphatase binding | molecular function | GO:0019903 | 166 | 21 | 20217 | 1400 |
Itpr1,Atp2b4,Smg7,Stat1,Phactr4,Cpd,Irs2,Stat3,Ptk2,Traf2,Mvp,Met,Sphk1,Slc9a1,Adrb2,Ppp6r1,Vcan,Stau1,Ap3b1,Ppp1r15a,Ppp2r2a |
| 5.399e-03 | -5.22 | mitotic cell cycle | biological process | GO:0000278 | 508 | 50 | 20694 | 1406 |
Rhoc,Rgcc,Ccng2,Spry2,Cdkn2d,Dync1h1,Trip13,Acvr1,Ccnj,Hinfp,Pim2,Cdkn1a,Pml,Rbbp8,Tuba4a,Plk3,Rhou,Daxx,Trim36,Cenpe,Setdb2,Cenpj,Mecp2,Azi2,Tpx2,Abcb1a,Chmp4b,Rgs14,Pttg1,Gpsm2,Mcm6,Ier3,Mdm2,Gpr132,Ccnd1,Inhba,Crlf3,Sbds,Vcpip1,Map2k1,Ppp2r2a,Rrs1,Gem,Ccne1,Casp2,Mitd1,Plk2,Ccnd2,Acvr1b,Atm |
| 5.404e-03 | -5.22 | positive regulation of binding | biological process | GO:0051099 | 202 | 24 | 20694 | 1406 |
Traf2,Bambi,Parp9,Ripk2,Rapgef2,Plk2,Csf3,Met,Plaur,Bmp2,Crbn,Jak2,Eno1,Cav1,Kat2b,Myc,Dtx3l,Plcl2,Irf4,Mmp9,Lgals9,Trib3,Agrn,Txn1 |
| 5.408e-03 | -5.22 | catabolic process | biological process | GO:0009056 | 1687 | 141 | 20694 | 1406 |
Psmb10,Tha1,Bnip3,Lipg,Mmp25,Oas2,Psmb6,Cnot4,Tmem67,Pfkl,Hk1,Zhx2,Uchl1,Irgm1,Noct,Bfar,Fnbp1l,Prdx1,Rnf19a,Ago3,Pla2g4a,Armc8,Uba7,Asah2,Eno2,Casp8,Pml,Plaat3,Smox,Rffl,Inpp5b,Magohb,Mmp9,Sirt1,Mdm2,Arel1,Isg15,Trim13,Txnrd1,Dram1,Polr2g,Tet2,Irf8,Cemip2,Il4i1,Sqstm1,Usp18,Hk2,Helz2,Adhfe1,Trim30a,Keap1,Fbxo4,Ldha,Sat1,Slfn8,Ube2l6,Samhd1,Ctsc,Tpi1,Ddhd1,Isg20,Ubr4,Acsl1,Upp1,Tent4a,Atm,Mgat1,Ankib1,Lnpep,Dcp1a,Zfp36,Dtx3l,Pde5a,Kmo,Enpp4,Rnf19b,Cop1,Mmp14,Gda,Birc2,Xrn1,Tent2,Esd,Rubcnl,Pla2g7,Dnajb2,Klhl25,Psmb9,Gtpbp2,Arrdc4,Dcp2,S100a8,Dio2,Psmb8,Cnp,Znrf3,Apobec3,Mmp13,Rnf34,Inpp1,Usp42,Hdc,Pnpt1,Trim12a,Spsb1,Zc3h12a,Rnf139,Hk3,Optn,Dnase1l3,Chmp4b,Prdx5,Gsta3,Crbn,Lipe,Znrf1,Hmox1,Tnfaip3,Pgk1,Peli1,Smpdl3b,Tut7,Ldlr,Smg7,Aoah,Rnaset2a,Hap1,Usp12,Traf2,Arg2,Usp25,1600014C10Rik,Gpc1,Nos2,Rnf14,Psma6,Gpd2,Lrp4,Irgm2,Phyh |
| 5.416e-03 | -5.22 | GO_TRANSCRIPTION_FACTOR_ACTIVITY_PROTEIN_BINDING | MSigDB lists | GO_TRANSCRIPTION_FACTOR_ACTIVITY_PROTEIN_BINDING | 539 | 60 | 15632 | 1249 |
Tcf4,Eno1,Birc2,Rbbp8,Nr3c1,Hdac1,Aebp2,Kdm5b,Rbpms,Ccnd1,Mecp2,Mxd1,Lif,Pml,Zfp281,Hif1a,Ripk3,Daxx,Notch1,Ncoa7,Relb,Cdyl,Junb,Med21,Sap30,Nmi,Nfkbid,Trib3,Arid5b,Nfkb2,Zhx2,Tfec,Psip1,Cited2,Jun,Hmga1,Atf3,Nfkbiz,Bcor,Kat2b,Nr1h3,Ciita,Hinfp,Klf7,Rnf14,Ccne1,Ahrr,Zeb1,Spen,Med13,Trip13,Nfkbib,Sirt1,Mtdh,Max,Dr1,Notch2,Rap2c,Lhx2,Nfil3 |
| 5.427e-03 | -5.22 | Ntn_hydrolases_N | interpro domains | IPR029055 | 31 | 7 | 19984 | 1430 |
Psmb6,Gfpt1,Psmb10,Psmb8,Asns,Psma6,Psmb9 |
| 5.429e-03 | -5.22 | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | 300 | 37 | 15632 | 1249 |
P4ha1,Lmo4,P2ry2,Plscr1,Sh3bp4,Rasgrp1,Ak4,Acsl1,Lyn,Plcl2,Idi1,Prkx,Cldnd1,Igf2bp2,Prkar2b,Trim36,Psip1,Abcc5,Ccl12,Mtus1,Tspan3,Swap70,Rbbp8,Peli1,Myc,Optn,Cers6,Mid1,Dusp4,Nck1,Kmo,Plagl1,Papss2,Cx3cl1,Rnd1,Slc16a1,Atp11b |
| 5.436e-03 | -5.21 | GO_UBIQUITIN_LIKE_PROTEIN_TRANSFERASE_ACTIVITY | MSigDB lists | GO_UBIQUITIN_LIKE_PROTEIN_TRANSFERASE_ACTIVITY | 392 | 46 | 15632 | 1249 |
Rnf19a,Ube2e2,Trim56,Trim21,Ubr4,Rnf31,Rnf14,Rabgef1,Birc3,Ankib1,Znrf1,Rnf145,Cnot4,Peli1,Nlrc4,Rnf114,Spsb1,Trim36,Fbxo4,Herc3,Znrf3,Mul1,Trim13,Bcor,Uba7,Ube2l6,Med21,Keap1,Rnf19b,Herc6,Mdm2,Rnf24,Rffl,Birc2,Traf2,Tnfaip3,Ube2f,Bfar,Rnf34,Traf5,Trim12c,Rnf135,Dtx3l,Rnf139,Malt1,Ube2e1 |
| 5.438e-03 | -5.21 | REACTOME_DOWNSTREAM_TCR_SIGNALING | MSigDB lists | REACTOME_DOWNSTREAM_TCR_SIGNALING | 28 | 7 | 15632 | 1249 |
H2-Aa,Ikbkg,Ripk2,H2-Eb1,Nfkbia,Malt1,Tab2 |
| 5.438e-03 | -5.21 | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN | MSigDB lists | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN | 28 | 7 | 15632 | 1249 |
Cd14,Cxcl14,Tmem176b,Ptger4,C3,Socs3,Fosb |
| 5.438e-03 | -5.21 | GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MIGRATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MIGRATION | 28 | 7 | 15632 | 1249 |
Ccl4,Cxcl14,Tnfrsf14,Ccl5,Itga4,Cxcl10,Tnfsf14 |
| 5.438e-03 | -5.21 | GO_REGULATION_OF_CELLULAR_EXTRAVASATION | MSigDB lists | GO_REGULATION_OF_CELLULAR_EXTRAVASATION | 28 | 7 | 15632 | 1249 |
Ripk3,Ccl12,Ptger4,Abr,Itga4,Ptafr,Icam1 |
| 5.438e-03 | -5.21 | WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_UP | MSigDB lists | WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_UP | 28 | 7 | 15632 | 1249 |
Thbs1,Igsf6,Alas1,Tfec,Gda,Ccnd2,Mtus1 |
| 5.438e-03 | -5.21 | VALK_AML_CLUSTER_4 | MSigDB lists | VALK_AML_CLUSTER_4 | 28 | 7 | 15632 | 1249 |
Itga4,Abcb1a,Dram1,Il4ra,Cyfip1,Klf2,Trib1 |
| 5.438e-03 | -5.21 | REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING | MSigDB lists | REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING | 28 | 7 | 15632 | 1249 |
Gnb4,Akt3,Gng4,Pik3r5,Gng11,Gng12,Pik3r6 |
| 5.438e-03 | -5.21 | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | MSigDB lists | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 28 | 7 | 15632 | 1249 |
Ccnd2,Gadd45b,Cd55,Mdfic,Me1,Htra1,Myc |
| 5.438e-03 | -5.21 | BIOCARTA_TNFR1_PATHWAY | MSigDB lists | BIOCARTA_TNFR1_PATHWAY | 28 | 7 | 15632 | 1249 |
Traf2,Casp8,Jun,Map2k4,Tnf,Casp2,Casp3 |
| 5.438e-03 | -5.21 | BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN | 28 | 7 | 15632 | 1249 |
Plaur,Phlda1,Flnb,Ier3,Ptgs2,Gja1,Hsph1 |
| 5.446e-03 | -5.21 | GO_DEFENSE_RESPONSE_TO_GRAM_NEGATIVE_BACTERIUM | MSigDB lists | GO_DEFENSE_RESPONSE_TO_GRAM_NEGATIVE_BACTERIUM | 35 | 8 | 15632 | 1249 |
Optn,Tnfrsf14,Trem1,Serpine1,Nos2,Il12b,Tlr9,Il6 |
| 5.446e-03 | -5.21 | ZHAN_MULTIPLE_MYELOMA_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_DN | 35 | 8 | 15632 | 1249 |
Vcam1,Pla2g7,Prkar2b,Pf4,Cebpd,Hhex,Syk,Lcn2 |
| 5.451e-03 | -5.21 | GO_REGULATION_OF_LIPID_TRANSPORT | MSigDB lists | GO_REGULATION_OF_LIPID_TRANSPORT | 91 | 15 | 15632 | 1249 |
Kdm5b,Sirt1,Edn1,Ptch1,P2ry2,Syk,Itgav,Nfkb1,Nfkbia,Il1b,Lipg,Tspo,Thbs1,Irs2,Nr1h3 |
| 5.453e-03 | -5.21 | GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 | MSigDB lists | GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 | 280 | 35 | 15632 | 1249 |
Nsmaf,Nr4a3,Map2k4,Fcho2,Dyrk2,Itga5,Ptger4,Cpeb4,Snn,Adam19,Rsbn1,Vps54,Klf2,Myo1b,Sesn3,Cd69,G3bp2,Phlpp2,Slc9a1,Btg2,Arrdc4,Pikfyve,Sertad3,Kat2b,Rgs3,Tmem184b,P2ry13,Itpr1,Bcl2l11,Itgav,Morc3,Sdc2,Prkce,Egr2,D1Ertd622e |
| 5.457e-03 | -5.21 | striated muscle tissue development | biological process | GO:0014706 | 328 | 35 | 20694 | 1406 |
Homer1,Flnb,Ifrd1,Nupr1,Maff,Egr1,Cav1,Pdgfrb,Btg2,Myc,Sgcb,Hivep3,Notch1,Kdm6b,Rcan1,Egr2,Cited2,Cacybp,Plagl1,Psma6,Fos,Sap30,Cflar,Bcl9,Hlx,Angpt1,Met,Sema3c,Slc9a1,Map2k4,Nr4a1,Bmp2,Acvr1,Casp8,Atf3 |
| 5.470e-03 | -5.21 | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_DN | MSigDB lists | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_DN | 154 | 22 | 15632 | 1249 |
Dse,Gramd1a,Arid4a,Sele,Treml2,Myc,Peli1,Tlr1,Tnfsf8,Zeb1,Slco3a1,Sell,Calcrl,Filip1l,Arl5c,Pmepa1,Rab3ip,Epsti1,Ikbke,Znrf1,Rras2,Crlf3 |
| 5.470e-03 | -5.21 | GSE22342_CD11C_HIGH_VS_LOW_DECIDUAL_MACROPHAGES_DN | MSigDB lists | GSE22342_CD11C_HIGH_VS_LOW_DECIDUAL_MACROPHAGES_DN | 154 | 22 | 15632 | 1249 |
Calcrl,Rnf145,Ubash3b,Slc25a22,Shisa3,Ptk2,H3f3b,Traf5,Cd300lf,Cyfip1,Pik3r6,Pde4b,Tor3a,Srm,Trmt1l,Txnrd1,Tmem26,I830077J02Rik,Ube2l6,Mdn1,Noc4l,H2-Aa |
| 5.470e-03 | -5.21 | GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 154 | 22 | 15632 | 1249 |
Pcgf5,Cxcl1,Zhx2,Junb,Ankib1,Abtb2,Psat1,Gch1,Srxn1,Plk3,Ier2,Isg15,Slc25a25,Hsph1,Srm,Txnrd1,Homer1,Ets2,Slc39a4,Stap1,Katna1,Egr2 |
| 5.470e-03 | -5.21 | GSE6269_STAPH_AUREUS_VS_STREP_PNEUMO_INF_PBMC_UP | MSigDB lists | GSE6269_STAPH_AUREUS_VS_STREP_PNEUMO_INF_PBMC_UP | 154 | 22 | 15632 | 1249 |
Hdc,Insl6,Tor3a,Eif2ak2,Met,Hk2,Scarf1,Optn,Phlda1,Antxr1,Trim14,Serpinb9,St3gal6,Aldh1b1,Parp11,Rcn1,Gng4,Ppfibp1,Etv5,Gpc1,Clcn7,Sdc4 |
| 5.470e-03 | -5.21 | GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_UP | MSigDB lists | GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_UP | 154 | 22 | 15632 | 1249 |
Dusp1,Crbn,Ift57,B3gnt5,S1pr2,Dusp8,Rab9,Sat1,Irs2,Palld,Dusp14,Atp11b,Gng11,Plk2,Slc4a7,Slpi,Gpr85,Dusp5,Mmp9,Igf1r,Cldnd1,Dr1 |
| 5.475e-03 | -5.21 | GTGACGY_E4F1_Q6 | MSigDB lists | GTGACGY_E4F1_Q6 | 582 | 64 | 15632 | 1249 |
Slc31a1,Dusp5,Gng4,Rcan1,Nr4a3,Pcdh7,Nfkb2,Pkp4,Ppp2r2a,Sec24b,Mthfd1l,Junb,Plk2,Ppp1r15a,Fosb,Ascc3,Tmeff1,Noc4l,Stxbp3,G3bp2,Maff,Hk2,Slc39a13,Arg2,Relb,Slc25a37,Dusp1,Armcx6,Zmynd15,Ankrd17,Rbbp8,Stat3,Egr2,Egr3,Ell2,Dnajb4,Trib1,Adrb2,Arf4,Tax1bp1,Abcc1,Cdkn1a,Psmb8,Ubr4,Gem,Layn,Lrp8,Egr1,Ccnd2,Nmral1,Gmppb,Rbms2,Slc25a25,Prpf4,Tle3,Nr4a1,Flt1,Bcl2l11,Dnaja1,Il6,Phlpp1,S1pr2,Ift57,Dusp4 |
| 5.502e-03 | -5.20 | monosaccharide binding | molecular function | GO:0048029 | 85 | 13 | 20217 | 1400 |
Hk2,Plod2,Siglece,Gys1,Plod3,Pfkl,Hk1,Phyh,P4ha2,P4ha1,Egln3,Clec4n,Hk3 |
| 5.507e-03 | -5.20 | KEGG_ARGININE_AND_PROLINE_METABOLISM | MSigDB lists | KEGG_ARGININE_AND_PROLINE_METABOLISM | 50 | 10 | 15632 | 1249 |
Sat1,P4ha2,Ass1,Srm,P4ha1,Odc1,Nos2,Lap3,Arg2,Aldh1b1 |
| 5.507e-03 | -5.20 | TONG_INTERACT_WITH_PTTG1 | MSigDB lists | TONG_INTERACT_WITH_PTTG1 | 50 | 10 | 15632 | 1249 |
Adap2,Ier3,Phf11d,Cnp,Plk3,Phf11b,Phf11c,Aebp2,Ppfibp2,Phf11a |
| 5.521e-03 | -5.20 | cellular component assembly | biological process | GO:0022607 | 2201 | 179 | 20694 | 1406 |
Cycs,Adar,Mpp7,Ripk3,Hat1,Crkl,Flrt3,Nlrc4,Mcm6,Pdss1,Nlrp3,Optn,Abcc4,Swap70,Apba1,Kcna3,Lpar1,Ikbke,Gpc1,Dst,Pdgfb,Marcks,Lcn2,Kcnj2,Snx10,Hcls1,Tapbp,Map2k1,Cox17,Sass6,Src,Nupr1,Dgkh,S1pr2,Ntng2,Triobp,Rhoq,Birc2,Rab3ip,Ptk2,Rac3,Pdgfrb,Plagl2,Fzd5,Hopx,Rhou,Pnpt1,Mecp2,Cenpj,Birc3,Ezr,Sco1,Apaf1,Pf4,Evl,Keap1,Psmd10,Dnaaf3,Itgav,Gja1,Rhof,Diaph2,Mdm2,Mlkl,Lrrc8c,Pdgfc,Vasp,Cflar,Ttc39c,Lox,G3bp2,Itga5,Samhd1,Cd34,Prdm9,Prnp,Stxbp3,Brd2,Tmem67,Rnd1,Agrn,Plod3,P2ry12,Cx3cl1,Atp6v1d,Gfpt1,Spata13,Denr,Pikfyve,Gch1,Fnbp1l,H3f3b,Nck1,Ift57,Me1,Irgm1,Sbds,Mx2,Rnd3,Tlr2,Hmox1,Vcpip1,Mx1,Chmp4b,Zc3h12a,Mdn1,Tifa,Lrp4,Irgm2,Tmod3,Rilpl1,Traf2,Micall2,Tapbpl,Rrs1,Myo1b,Carmil1,Nod2,Pkp4,Fas,Tap2,Trip13,Trim21,Homer1,Rhoc,Nectin2,Ehd1,Mcoln2,Cenpe,Asf1a,Intu,Cav1,Spire1,Sqstm1,Dbnl,Rab32,Itpr1,Txnrd1,Kctd12,Csrp1,Slc2a1,Mmp9,Cox18,Cyfip1,Rapgef2,Whamm,Coa5,Jmjd6,Ccl5,Nlgn2,Igf1r,Pfkl,Psip1,Cutc,Dync1h1,Cd74,Max,Rpgrip1l,Fscn1,Malt1,Gsdmd,Fcho2,Tcf4,Sod2,Snx2,Daxx,Tpx2,Stxbp1,Zyx,Pml,Ciapin1,Rasgrp1,Ago3,Acpp,Pstpip2,Rab20,Angpt1,Noct,Ikzf1 |
| 5.533e-03 | -5.20 | negative regulation of developmental growth | biological process | GO:0048640 | 127 | 17 | 20694 | 1406 |
Cdk5r1,Mecp2,Ifrd1,Cited2,Ptch1,Gja1,Sema4c,Cdkn1a,Sema4a,Jarid2,Ptk2,Sav1,Tomm70a,Plac8,Sema3c,Gdf15,Adrb2 |
| 5.533e-03 | -5.20 | positive regulation of cell-substrate adhesion | biological process | GO:0010811 | 127 | 17 | 20694 | 1406 |
Map4k4,Thbs1,Hsd17b12,Rac3,Ptprj,Sdc4,Kdr,Jak2,Triobp,Itga5,Vegfc,Crkl,Myadm,Csf1,Plekha2,Prkce,Carmil1 |
| 5.564e-03 | -5.19 | GSE28237_EARLY_VS_LATE_GC_BCELL_DN | MSigDB lists | GSE28237_EARLY_VS_LATE_GC_BCELL_DN | 173 | 24 | 15632 | 1249 |
Ttc39b,Sema4a,Atp10a,Parp3,Pkp4,Plcl2,Abtb2,Vasp,Reps1,Spen,Psme2,Agtrap,Evl,Abr,Angpt1,Rhoc,Zfp319,Tspo,Acpp,Gramd1a,Apobec3,Ythdf1,Tapbp,Atp13a1 |
| 5.564e-03 | -5.19 | GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_UP | MSigDB lists | GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_UP | 173 | 24 | 15632 | 1249 |
Tal2,Zbp1,Arl4a,Cdk5r1,Fgr,Gpr35,Dock10,Fam43a,Phldb1,Tcf4,Cd40,Nfkb2,Chd9,Cmpk2,Hsd17b7,Tlr3,Trib1,Spire1,Zc3h7a,Cnn3,Tlr1,Gch1,Ppm1k,Hopx |
| 5.564e-03 | -5.19 | GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN | MSigDB lists | GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN | 173 | 24 | 15632 | 1249 |
Sell,Hhex,Chst11,Ifrd1,4932438A13Rik,Rab11fip1,Cd302,P2ry13,Zyx,Rgs14,Fos,Abcc5,Aoah,Parp8,Slc25a37,5430427O19Rik,Il18,Mppe1,Ldha,Fam53c,Etv6,Lmo4,Slc7a2,Tuba4a |
| 5.569e-03 | -5.19 | GO_NUCLEIC_ACID_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | GO_NUCLEIC_ACID_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 999 | 102 | 15632 | 1249 |
Stat5a,Klf6,Bcl6,Tcf4,Ifi209,Stat3,Batf2,Mecp2,Mafk,Hdac1,Aebp2,Prdm1,Csrnp1,Zfp281,Batf,Pbx1,Etv5,Plagl2,Irf7,Fosb,Rcan1,Nr4a3,Arid5b,Nfkb2,Klf3,Nr4a1,Spic,Ets2,Cited2,Hmga1,Ifi214,Nr1h3,Klf7,Foxp4,Aff1,Ifi207,Ahr,Jdp2,Nfkb1,Rel,Mndal,Lmo4,Ifi211,Zeb1,Zscan29,Etv6,Pou2f2,Egr3,Max,Ifi204,Nfil3,Ifi213,Sp140,Ifi205,Eno1,Nr3c1,Egr2,Kdm5b,Cebpd,Irf2,Mxd1,Hhex,Hif1a,Stat2,Tal2,Notch1,Relb,Junb,Jarid2,Arid4a,Klf2,Fubp1,Btg2,Ifi208,Maff,Nfxl1,Tfec,Zhx2,Hivep2,Znfx1,Fos,Jun,Irf4,Ikzf1,Myc,Taf4b,Atf3,Egr1,Plagl1,Etv3,Pttg1,Hinfp,Dach1,Irf8,Plscr1,Stat4,Hivep3,Ifi203,Stat1,Irf1,Mafg,Gfi1 |
| 5.572e-03 | -5.19 | Integrin_alpha_C_CS | interpro domains | IPR018184 | 17 | 5 | 19984 | 1430 |
Itgal,Itga9,Itgav,Itga5,Itga4 |
| 5.572e-03 | -5.19 | Cyclin | interpro domains | IPR039361 | 17 | 5 | 19984 | 1430 |
Ccnd1,Ccnj,Ccng2,Ccne1,Ccnd2 |
| 5.573e-03 | -5.19 | GO_DEFENSE_RESPONSE_TO_GRAM_POSITIVE_BACTERIUM | MSigDB lists | GO_DEFENSE_RESPONSE_TO_GRAM_POSITIVE_BACTERIUM | 66 | 12 | 15632 | 1249 |
Il6,Tnfsf8,H2-Q4,Tnf,H2-Q6,Nod1,Myd88,Tnfrsf14,H2-Q7,Ripk2,Fgr,Tlr2 |
| 5.573e-03 | -5.19 | RODRIGUES_THYROID_CARCINOMA_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_DN | 66 | 12 | 15632 | 1249 |
Hivep2,Nampt,Bbx,Itgb8,Tra2a,Lif,Tab2,Irf1,Thbs1,Pmepa1,Dcbld2,Igf2bp2 |
| 5.574e-03 | -5.19 | Atf4 (activating transcription factor 4) | protein interactions | 11911 | 13 | 5 | 7778 | 753 |
Trib3,Hif1a,Egln3,Fos,Jun |
| 5.594e-03 | -5.19 | sensory organ development | biological process | GO:0007423 | 583 | 56 | 20694 | 1406 |
Tdrd7,Gja1,Inhba,Nr4a3,Rcn1,Ahr,Mapkapk2,Gfi1,Notch1,Ppp2r3a,Pdgfb,Lif,Slc25a25,Casz1,Hif1a,Flt1,Abr,Jag1,Ttc39c,Gpd2,Lhx2,Stat3,Bcl2l11,Bmp2,Clic4,Triobp,Edn1,Tshz1,Cxcl14,Tsku,Jmjd6,Zhx2,Spry2,Notch2,Myc,Sec24b,Rpgrip1l,Slc4a7,Fzd5,Cebpd,Pdgfrb,Zeb1,Clic5,Phactr4,Tulp3,Cited2,Kdr,Jun,Ifi204,Prdm1,Hdac1,Ikzf1,Acvrl1,Zfp513,Sdc4,Eya4 |
| 5.620e-03 | -5.18 | negative regulation of interleukin-2 production | biological process | GO:0032703 | 25 | 6 | 20694 | 1406 |
Ezr,Cd34,Nod2,Tnfaip3,Zfp36,Prnp |
| 5.620e-03 | -5.18 | positive regulation of hemostasis | biological process | GO:1900048 | 25 | 6 | 20694 | 1406 |
Pdpn,Ptprj,Enpp4,Serpine1,Plek,Thbs1 |
| 5.620e-03 | -5.18 | regulation of platelet-derived growth factor receptor signaling pathway | biological process | GO:0010640 | 25 | 6 | 20694 | 1406 |
Glrx,Lox,Ptgir,Ptprj,Src,Ptpn2 |
| 5.620e-03 | -5.18 | positive regulation of erythrocyte differentiation | biological process | GO:0045648 | 25 | 6 | 20694 | 1406 |
Isg15,Inhba,Stat1,Hif1a,Stat3,Acvr1b |
| 5.620e-03 | -5.18 | negative regulation of type I interferon production | biological process | GO:0032480 | 25 | 6 | 20694 | 1406 |
Relb,Rel,Acod1,Gbp4,Nmi,Dhx58 |
| 5.620e-03 | -5.18 | response to copper ion | biological process | GO:0046688 | 25 | 6 | 20694 | 1406 |
Prnp,Mt1,Il1a,Daxx,Mt2,Cp |
| 5.620e-03 | -5.18 | positive regulation of blood coagulation | biological process | GO:0030194 | 25 | 6 | 20694 | 1406 |
Plek,Enpp4,Ptprj,Pdpn,Thbs1,Serpine1 |
| 5.620e-03 | -5.18 | protein hydroxylation | biological process | GO:0018126 | 25 | 6 | 20694 | 1406 |
Plod3,P4ha2,P4ha1,Egln3,Jmjd6,Plod2 |
| 5.620e-03 | -5.18 | regulation of glutamate secretion | biological process | GO:0014048 | 25 | 6 | 20694 | 1406 |
Il1b,Il1rn,Kmo,Adora2a,Nr3c1,Stxbp1 |
| 5.620e-03 | -5.18 | negative regulation of antigen receptor-mediated signaling pathway | biological process | GO:0050858 | 25 | 6 | 20694 | 1406 |
Prnp,Ptpn2,Plcl2,Ptprj,Fcgr2b,Ezr |
| 5.621e-03 | -5.18 | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN | 58 | 11 | 15632 | 1249 |
Dock4,Flrt2,Cav1,C3,Clic5,Rgl1,Atp2b4,Rhoq,Kdr,Procr,Bnip3 |
| 5.621e-03 | -5.18 | GO_NEGATIVE_REGULATION_OF_WOUND_HEALING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_WOUND_HEALING | 58 | 11 | 15632 | 1249 |
Gja1,Ubash3b,Adrb2,Serpine1,Plau,Cd34,Pdgfb,Edn1,Serpinb2,Plat,Plaur |
| 5.621e-03 | -5.18 | PID_NOTCH_PATHWAY | MSigDB lists | PID_NOTCH_PATHWAY | 58 | 11 | 15632 | 1249 |
Rbbp8,Eno1,Spen,Myc,Ccnd1,Hdac1,Jag1,Notch2,Mark2,Notch1,Cdkn1a |
| 5.621e-03 | -5.18 | GO_LEUKOCYTE_HOMEOSTASIS | MSigDB lists | GO_LEUKOCYTE_HOMEOSTASIS | 58 | 11 | 15632 | 1249 |
Bcl2l11,Pde4b,Tnfsf14,Il6,Casp3,Fas,Lyn,Hif1a,Tnfaip3,Hcar2,Ripk3 |
| 5.628e-03 | -5.18 | LE_EGR2_TARGETS_DN | MSigDB lists | LE_EGR2_TARGETS_DN | 100 | 16 | 15632 | 1249 |
Slc2a1,Tiparp,Myo1b,Fut8,Abcb1a,Fgl2,Errfi1,Rtn1,Cd55,Hmgcs1,Slco3a1,Lox,Idi1,Pim3,Me1,Cdkn1a |
| 5.628e-03 | -5.18 | WOOD_EBV_EBNA1_TARGETS_UP | MSigDB lists | WOOD_EBV_EBNA1_TARGETS_UP | 100 | 16 | 15632 | 1249 |
Slco3a1,Icam1,Stat1,C3,Dusp14,Inpp1,Hspa1a,Txnrd1,Itgav,Ass1,Apobec3,Nqo1,Rbpms,Myc,Gclm,Ctsc |
| 5.628e-03 | -5.18 | GO_FAT_CELL_DIFFERENTIATION | MSigDB lists | GO_FAT_CELL_DIFFERENTIATION | 100 | 16 | 15632 | 1249 |
Socs7,Lrrc8c,Nr4a3,Socs1,Adrb2,Arl4a,Arid5b,Ptgs2,Sirt1,Ccnd1,Egr2,Bnip3,Pid1,Psmb8,Nr4a1,Plac8 |
| 5.653e-03 | -5.18 | type 5 metabotropic glutamate receptor binding | molecular function | GO:0031802 | 6 | 3 | 20217 | 1400 |
Adora2a,Homer1,Prnp |
| 5.653e-03 | -5.18 | L-aspartate transmembrane transporter activity | molecular function | GO:0015183 | 6 | 3 | 20217 | 1400 |
Slc25a12,Slc25a22,Slc13a3 |
| 5.673e-03 | -5.17 | negative regulation of insulin receptor signaling pathway | biological process | GO:0046627 | 41 | 8 | 20694 | 1406 |
Ptpn2,Socs3,Cish,Nck1,Socs1,Il1b,Ncoa5,Pid1 |
| 5.685e-03 | -5.17 | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_180MIN_DN | 136 | 20 | 15632 | 1249 |
Nr3c1,Nrp2,Igsf6,Optn,Tdrd7,Il27,Fam102b,Pbx1,Gpc1,Dusp16,Tnfrsf14,Gfi1,Smox,Rnf19b,Tmem176b,Itga4,Rtn1,Parp3,Ubash3b,Irs2 |
| 5.729e-03 | -5.16 | Proteasome_suB-type | interpro domains | IPR023333 | 11 | 4 | 19984 | 1430 |
Psmb9,Psmb10,Psmb8,Psmb6 |
| 5.740e-03 | -5.16 | regulation of exocytosis | biological process | GO:0017157 | 248 | 28 | 20694 | 1406 |
Il4ra,Lyn,Prkce,Hmox1,Rabgef1,Sdc1,Rab10,Fgr,Rims3,Stxbp3,Lgals9,Notch1,Htr2a,Apba1,Abr,Cacna1d,Adora2a,P2ry2,Syk,Ptafr,Stxbp1,Rab21,Hap1,Adora2b,Glrx,Sdc4,Adrb2,Rab9 |
| 5.741e-03 | -5.16 | regulation of fatty acid metabolic process | biological process | GO:0019217 | 87 | 13 | 20694 | 1406 |
Sirt1,Gk,Pla2g4a,Pdk3,Il1b,Nr1h3,Trib3,Fabp3,Acsl5,Ptgs2,Nr4a3,Cav1,Irs2 |
| 5.744e-03 | -5.16 | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN | MSigDB lists | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN | 164 | 23 | 15632 | 1249 |
Tcf4,Irf8,Myo1b,Syk,Treml2,Phlpp2,Slc15a3,Timeless,Irf4,Fpr2,Cd200,Hmgcs1,Hhex,H2-Ab1,Dram1,Dnase1l3,Cd80,Fbxo4,Adam19,Ust,Rras2,Nod1,Gtpbp2 |
| 5.744e-03 | -5.16 | GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_UP | MSigDB lists | GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_UP | 164 | 23 | 15632 | 1249 |
Trim14,Bcorl1,Ddit4,Csrp1,Dnajb2,Dusp16,Usp31,Dusp4,Ccl2,Ubtd2,Rab9,Oaf,Nr3c1,H2-Q6,Ass1,H2-Q4,Tnfaip3,Batf,Pfkfb3,Socs1,Nxf1,Mcoln2,H2-Q7 |
| 5.744e-03 | -5.16 | GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_DN | MSigDB lists | GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_DN | 164 | 23 | 15632 | 1249 |
Bcl2l11,Otud1,Rab9,Tgs1,Tlr6,Hhex,Sertad3,Etv5,Tor3a,Clic5,Adap2,Myo1b,Tmem26,Stat1,Ripk2,Ptger4,Frmd4a,Nsmaf,Tgfbi,Gca,Slc29a3,Bambi,Elmod2 |
| 5.745e-03 | -5.16 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_1H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_1H_ACT_CD4_TCELL_DN | 127 | 19 | 15632 | 1249 |
Traf1,Nlrp3,Foxp4,Pmepa1,Xcr1,Clec4e,Kitl,Gadd45b,Src,Gypc,Rin2,Gpr68,Dusp4,Rap1gap2,Gadd45g,Ddit4,Phgdh,Tmem171,Gpr35 |
| 5.756e-03 | -5.16 | GO_LEUKOCYTE_MIGRATION_INVOLVED_IN_INFLAMMATORY_RESPONSE | MSigDB lists | GO_LEUKOCYTE_MIGRATION_INVOLVED_IN_INFLAMMATORY_RESPONSE | 10 | 4 | 15632 | 1249 |
Ccl12,S100a8,Cx3cl1,Sele |
| 5.756e-03 | -5.16 | YAGUE_PRETUMOR_DRUG_RESISTANCE_DN | MSigDB lists | YAGUE_PRETUMOR_DRUG_RESISTANCE_DN | 10 | 4 | 15632 | 1249 |
Frmd4a,Dse,Vcan,Ltbp2 |
| 5.756e-03 | -5.16 | IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS | MSigDB lists | IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS | 10 | 4 | 15632 | 1249 |
Tnfaip3,Nfkb1,Isg20,Atf3 |
| 5.756e-03 | -5.16 | TSUDA_ALVEOLAR_SOFT_PART_SARCOMA | MSigDB lists | TSUDA_ALVEOLAR_SOFT_PART_SARCOMA | 10 | 4 | 15632 | 1249 |
Mapkapk2,Pim1,Met,Lyn |
| 5.756e-03 | -5.16 | GO_NEGATIVE_REGULATION_BY_HOST_OF_VIRAL_TRANSCRIPTION | MSigDB lists | GO_NEGATIVE_REGULATION_BY_HOST_OF_VIRAL_TRANSCRIPTION | 10 | 4 | 15632 | 1249 |
Jun,Hdac1,Ccl5,Ccl4 |
| 5.756e-03 | -5.16 | ZHENG_RESPONSE_TO_ARSENITE_UP | MSigDB lists | ZHENG_RESPONSE_TO_ARSENITE_UP | 10 | 4 | 15632 | 1249 |
Gclm,Hmox1,Txnrd1,Slc30a1 |
| 5.756e-03 | -5.16 | GO_POSITIVE_REGULATION_OF_CAMP_MEDIATED_SIGNALING | MSigDB lists | GO_POSITIVE_REGULATION_OF_CAMP_MEDIATED_SIGNALING | 10 | 4 | 15632 | 1249 |
Pf4,Cxcl10,Rapgef2,Ptgir |
| 5.756e-03 | -5.16 | GO_NEGATIVE_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION | 10 | 4 | 15632 | 1249 |
Cav1,Errfi1,Jun,Mvp |
| 5.756e-03 | -5.16 | GO_REGULATION_OF_CYTOKINE_SECRETION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_REGULATION_OF_CYTOKINE_SECRETION_INVOLVED_IN_IMMUNE_RESPONSE | 10 | 4 | 15632 | 1249 |
Tnf,Tnfrsf14,Il10,Angpt1 |
| 5.756e-03 | -5.16 | GO_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN | MSigDB lists | GO_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN | 10 | 4 | 15632 | 1249 |
Osm,Lif,Jak2,Il15 |
| 5.756e-03 | -5.16 | HEDVAT_ELF4_TARGETS_UP | MSigDB lists | HEDVAT_ELF4_TARGETS_UP | 10 | 4 | 15632 | 1249 |
Cxcl1,Abcb1a,Hdc,Rcan1 |
| 5.756e-03 | -5.16 | GO_DETECTION_OF_MOLECULE_OF_BACTERIAL_ORIGIN | MSigDB lists | GO_DETECTION_OF_MOLECULE_OF_BACTERIAL_ORIGIN | 10 | 4 | 15632 | 1249 |
Tlr2,Nod2,Tlr1,Tlr6 |
| 5.756e-03 | -5.16 | GO_MACROPHAGE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_MACROPHAGE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 10 | 4 | 15632 | 1249 |
Tlr3,Cx3cr1,Prkce,Syk |
| 5.756e-03 | -5.16 | GO_MHC_CLASS_II_PROTEIN_COMPLEX | MSigDB lists | GO_MHC_CLASS_II_PROTEIN_COMPLEX | 10 | 4 | 15632 | 1249 |
Cd74,H2-Aa,H2-Ab1,H2-Eb1 |
| 5.756e-03 | -5.16 | GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_FISSION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_FISSION | 10 | 4 | 15632 | 1249 |
Bnip3,Ddhd1,Kdr,Mul1 |
| 5.756e-03 | -5.16 | HINATA_NFKB_MATRIX | MSigDB lists | HINATA_NFKB_MATRIX | 10 | 4 | 15632 | 1249 |
Mmp14,Serpinb2,Rnd3,Serpine1 |
| 5.762e-03 | -5.16 | GO_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | 118 | 18 | 15632 | 1249 |
Nsmaf,Fabp3,Nr1h3,Trib3,Ptgs2,C3,Gfi1,Htr2b,Il1b,Htr2a,Bmp2,Tspo,Ldlr,Nfkb1,Tnf,Sirt1,Pdgfb,Pla2g4a |
| 5.766e-03 | -5.16 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_UP | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_UP | 183 | 25 | 15632 | 1249 |
Gsdmd,Agrn,Apobec3,Traf2,Cyfip1,Homer1,Dnaja1,Mapkbp1,Stau1,Cd164,Aim2,Plk3,Ddx60,Zfp281,Icam1,Ankib1,4930523C07Rik,Cep350,Plcl2,Irak2,Chic2,Phf6,4930453N24Rik,Spata5l1,Nr4a3 |
| 5.766e-03 | -5.16 | GSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_UP | MSigDB lists | GSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_UP | 183 | 25 | 15632 | 1249 |
Fscn1,Rgs1,Tnip1,Pfkl,Tgfbi,Rab20,Adrb2,Cdc42ep4,Isg20,Ccrl2,Junb,Lcp2,Gem,Fosb,Col4a2,Slc48a1,Gbp2,Irak3,Mmp14,Dbnl,Rai14,Dusp4,Tapbp,Klf6,Mrpl52 |
| 5.766e-03 | -5.16 | GSE20198_UNTREATED_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP | MSigDB lists | GSE20198_UNTREATED_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP | 183 | 25 | 15632 | 1249 |
Hap1,Tbc1d13,Rnf19a,Sesn3,Col27a1,Fscn1,Bcl2a1a,Dusp16,Asb13,Kif3c,Ak4,Ccl2,Rab11fip1,Ikzf1,Bcl2a1d,Hdac1,Treml2,Bcl2a1b,Tnf,Prrg4,Csrnp1,Pgs1,Irs2,Agtrap,Socs1 |
| 5.766e-03 | -5.16 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_6H_DN | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_6H_DN | 183 | 25 | 15632 | 1249 |
Ptger4,Smc5,Grina,Serpinb9,Gpd2,Fam111a,Frmd4a,Asf1a,Psat1,Cenpj,Ptch1,Kctd12,Slc30a4,Magohb,Tpx2,Sass6,Gpc1,Ripk3,Dusp1,Trim36,Insl6,Tcf4,Gpsm2,Irgq,Fgl2 |
| 5.766e-03 | -5.16 | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN | 183 | 25 | 15632 | 1249 |
Tap1,Ahr,Aff1,Gys1,Il15,Mthfr,Adora2a,Pid1,Cacybp,Rnaset2a,Gna15,Asah2,Daam1,Tap2,Cdkn1a,Epsti1,Pkp4,Rnaset2b,Tnfaip2,Col27a1,Whamm,Chic2,Cd200,Ppa1,Mtmr14 |
| 5.766e-03 | -5.16 | GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN | MSigDB lists | GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN | 183 | 25 | 15632 | 1249 |
Ms4a6d,Stat1,Fam20c,Pik3r6,Gbp7,Psmb8,Rap1gap2,Cd69,Parp12,Med13,Bcorl1,Akt3,Jmjd6,Dtx3l,Ubash3b,Egr1,Malt1,Nfkbiz,Vcpip1,Adar,Dnaja1,Errfi1,Treml2,Ly75,Rai14 |
| 5.766e-03 | -5.16 | GSE27786_NKCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_NKCELL_VS_NEUTROPHIL_UP | 183 | 25 | 15632 | 1249 |
Prdm1,Mthfr,Psmb10,Dtwd1,Ddhd1,Ttc39c,Sat1,Slfn8,Spry2,Dusp2,Nfkbie,Parp9,B3gnt5,Cmklr1,Slfn9,Pfkl,Stip1,Sesn3,Ppm1k,Pdgfb,Ext1,Psme2,Usp12,Snx2,Etv6 |
| 5.770e-03 | -5.16 | regulation of nuclear division | biological process | GO:0051783 | 192 | 23 | 20694 | 1406 |
Hspa1b,Met,Pdgfrb,Prdm9,Il1b,Chmp4b,Pttg1,Cenpe,Hspa1a,Phip,Edn1,Lif,Igf1r,Pdgfb,Trip13,Nek6,Atm,Sphk1,Rgcc,Il1a,Smc5,Tnf,Osm |
| 5.787e-03 | -5.15 | GO_HEAT_SHOCK_PROTEIN_BINDING | MSigDB lists | GO_HEAT_SHOCK_PROTEIN_BINDING | 83 | 14 | 15632 | 1249 |
Nfkb1,Nfkbia,Dnaja1,Hspa1a,Nod2,Dnaja2,Bcor,Hif1a,Kdr,Dnajb2,Ahr,Apaf1,Daxx,Stip1 |
| 5.808e-03 | -5.15 | negative regulation of myeloid cell differentiation | biological process | GO:0045638 | 97 | 14 | 20694 | 1406 |
Clec2d,Zfp36,Ptpn2,Nfkbia,Pf4,Pilrb1,Gpr68,Myc,Ifnb1,Stat5a,Trib1,Lyn,Tmem178,Ubash3b |
| 5.808e-03 | -5.15 | regulation of muscle adaptation | biological process | GO:0043502 | 97 | 14 | 20694 | 1406 |
Nr4a3,Errfi1,Edn1,Atp2b4,Notch1,Jarid2,Ptk2,Trip10,Sirt1,Tnfrsf1b,Nr3c1,Pde5a,Tomm70a,Slc9a1 |
| 5.834e-03 | -5.14 | HD/PDEase_dom | interpro domains | IPR003607 | 24 | 6 | 19984 | 1430 |
Pde5a,Pde4b,Pde3b,Pde7b,Pde1b,Samhd1 |
| 5.834e-03 | -5.14 | Interferon_alpha/beta/delta | interpro domains | IPR000471 | 24 | 6 | 19984 | 1430 |
Ifna1,Ifnb1,Ifna6,Ifna4,Ifna2,Ifna5 |
| 5.838e-03 | -5.14 | prostaglandin biosynthetic process | biological process | GO:0001516 | 18 | 5 | 20694 | 1406 |
Sphk1,Cd74,Ptges,Edn1,Ptgs2 |
| 5.838e-03 | -5.14 | establishment or maintenance of cytoskeleton polarity | biological process | GO:0030952 | 18 | 5 | 20694 | 1406 |
Rhoc,Rnd1,Rnd3,Rhof,Rictor |
| 5.838e-03 | -5.14 | reactive nitrogen species metabolic process | biological process | GO:2001057 | 18 | 5 | 20694 | 1406 |
Tlr2,Tlr6,Prdx5,Nos2,Slc7a2 |
| 5.838e-03 | -5.14 | negative regulation of peptidyl-threonine phosphorylation | biological process | GO:0010801 | 18 | 5 | 20694 | 1406 |
Spred1,Spry2,Met,Spred3,Ddit4 |
| 5.838e-03 | -5.14 | cellular response to angiotensin | biological process | GO:1904385 | 18 | 5 | 20694 | 1406 |
Src,Agtrap,Nfkb1,Igf1r,Cav1 |
| 5.838e-03 | -5.14 | prostanoid biosynthetic process | biological process | GO:0046457 | 18 | 5 | 20694 | 1406 |
Sphk1,Ptges,Cd74,Edn1,Ptgs2 |
| 5.838e-03 | -5.14 | negative regulation of interleukin-17 production | biological process | GO:0032700 | 18 | 5 | 20694 | 1406 |
Arg2,Tnfsf4,Tlr2,Il12b,Prnp |
| 5.838e-03 | -5.14 | xenobiotic transport | biological process | GO:0042908 | 18 | 5 | 20694 | 1406 |
Slc2a1,Abcc1,Lrrc8c,Abcc4,Abcb1a |
| 5.838e-03 | -5.14 | response to leptin | biological process | GO:0044321 | 18 | 5 | 20694 | 1406 |
Pid1,Ccnd1,Sirt1,Stat3,Nr4a3 |
| 5.838e-03 | -5.14 | negative regulation of membrane potential | biological process | GO:0045837 | 18 | 5 | 20694 | 1406 |
Prkce,Il1rn,Pmaip1,Il6,Bnip3 |
| 5.838e-03 | -5.14 | positive regulation of astrocyte differentiation | biological process | GO:0048711 | 18 | 5 | 20694 | 1406 |
Lif,Il1b,Bmp2,Notch1,Clcf1 |
| 5.838e-03 | -5.14 | cellular response to unfolded protein | biological process | GO:0034620 | 68 | 11 | 20694 | 1406 |
Hspa1b,Serp1,Ppp1r15a,Optn,Atf3,Hspa1a,Ero1l,Hspa2,Eif2ak2,Daxx,Ccnd1 |
| 5.838e-03 | -5.14 | positive regulation of intrinsic apoptotic signaling pathway | biological process | GO:2001244 | 68 | 11 | 20694 | 1406 |
Cav1,S100a8,Ripk3,Nupr1,Nck1,Plscr1,Sirt1,Bcl2l11,Ptpn2,Plagl2,Nox1 |
| 5.854e-03 | -5.14 | membrane part | cellular component | GO:0044425 | 7154 | 530 | 20747 | 1409 |
Marco,Pilrb1,Fcgr2b,Aftph,Slc39a14,Mul1,Pde3b,Asah2,Il13ra1,Sco1,Ier3,Gypc,Lpar1,Tnfsf4,P2ry13,Gnb4,Plaur,Lst1,Errfi1,Hsd17b7,Cd302,Itgav,Adgrl2,Dcbld2,Pcdh7,Slc25a12,Kremen1,Sema4c,Homer1,Traf2,Siglece,Slc28a2,Clmp,Slc12a9,Ric1,Il12rb1,Crkl,Cd38,Snx10,I830077J02Rik,Itgb8,Dst,Tmeff1,Stoml1,Bmp2,Mosmo,Pdpn,Itpr1,Piezo1,Nlgn2,Thbs1,Sema4a,Il15ra,Crim1,Gramd1a,Il18,Sgcb,Cacnb3,Higd1a,Csf3r,Stxbp3,Gpr68,Il18rap,Gng11,Degs2,Grk3,Rhbdf2,Tnfsf14,F830016B08Rik,Casp3,Mpp7,Armcx6,Slc2a6,Chmp4b,Slc7a5,Kcna3,Rtn2,Clic4,Cx3cr1,Flrt3,Ifi47,Clec5a,Tspan3,Clec4d,Syne2,Sdc2,H2-T22,Bnip3,Angpt1,Tlr3,Orai2,Arf4,Pde4b,Gsr,Src,Nectin2,Mark2,St3gal5,Mmp25,Spn,Nectin4,Nod1,Rgs1,Cldnd1,Cd14,Prkar2b,P2ry14,Gng12,Slc16a3,Cmklr1,Tmem176a,Slc29a3,Tmem123,Slco3a1,Tnfrsf14,Myadm,Eno1,B4galt4,Atp2b4,Gng4,Caml,Flt1,Cd200r4,Syk,Klra2,Slc16a1,Abcc1,Adrb2,Tap1,Cd80,Gem,Hcar2,Sipa1l1,Lrp8,Igsf9,Slc25a25,Tomm70a,Gpc1,Flrt2,Pgk1,Hmox1,Stx6,Lrp4,Apba1,Rapgef2,Ext1,Pilra,Ap3b1,Gpr132,Adgrg6,Sdc4,Itga4,Lyn,Sec24b,Grina,Znrf3,Mmp14,Ptgir,Lnpep,Procr,Ptch1,Mcoln2,Cemip2,Bcl2l11,Igsf6,P2ry12,Hvcn1,S1pr2,Kdr,Irgm2,Gpr18,Gpr35,Clcn5,Calhm6,Ptafr,Slamf8,Dbnl,Nrp2,Serp1,Socs1,Xcr1,Ap3m2,Slc43a3,Sdc1,St3gal1,Ehd1,Vcam1,Treml2,Mitd1,Fzd5,Kcnj2,Tapbp,Sell,Il4ra,Antxr1,Csf1,Birc2,Slc30a1,Gm4951,Pnpt1,Tmem229b,Ddx58,Mppe1,Ms4a6b,Gja1,Tmem178,Tnfrsf8,Itga5,Rhoc,Slamf7,Cp,Tmem176b,Cd300e,Cd74,Abcc5,Socs3,H2-Q4,Tlr1,H2-Aa,Ktn1,Enpp4,Slc15a3,Tnfsf8,Ly6c2,Cflar,Casp8,Actb,Tnfsf10,Tmtc2,Spire1,Fam241a,Sgms2,Slc31a1,St7,Milr1,Lcp2,Prnp,Vezt,Ezr,Mfsd7a,Scimp,Tmc3,Ust,Reps1,Rab10,St3gal3,Scarf1,Sema3c,Itgal,Agpat4,Tlr9,Cd274,Plpp3,Adora2a,Ms4a6c,Pgap2,Hk1,Kitl,Rims3,Trim13,Tarm1,Ms4a4b,Msr1,Mfap3l,Cav1,Acvr1b,Slc44a1,Rab21,Gpr85,Lnpk,H2-T10,Nod2,Atp13a1,Irgm1,Cx3cl1,Rsad2,Ccr1,Igsf8,Slc37a3,Klrk1,Pdgfb,Bambi,Rnf19b,Rab19,Acsl5,Zc3h12a,Ubr4,Axl,Tapbpl,Pdgfrb,Rmdn3,Tgtp1,Pik3r5,Spata13,Cd40,Adgre4,Plek,Socs7,Dhrs9,Gna15,Fam162a,Scn1b,Snx2,Cish,Ebi3,B3gnt5,Slc39a13,Susd6,Cept1,Ifitm1,Fcgr4,Samhd1,Il6,Treml4,Stra6l,Trp53i11,Fas,Met,Slc4a7,Fcgr1,Tgtp2,Plpp1,Acvrl1,F11r,Rhoh,Tpst1,Phlpp2,Ly6a,Atp6v1d,Extl2,Pml,Tspo,Sh3bp4,Dse,Gm5431,Stx11,Agtrap,Clcn7,Gm12185,Ptges,Rnf31,Sele,Ccr3,Ldlr,Noc4l,Spint2,Eva1b,Cyth3,Ptprj,Lrp11,Fpr2,Ppm1l,Raet1e,Vasn,Adora2b,Cpd,Snn,Gpr141,Ifnar1,Fcho2,H2-Ab1,AA467197,Kctd12,Nox1,Tmem219,Ch25h,Olfr56,Lrrc25,Shisa3,Pilrb2,Eno2,Tmem184b,Tmem171,Rnf19a,Rrbp1,H2-Eb1,Jak2,Prkce,Tnfrsf1b,Hspa2,1600014C10Rik,Igf1r,Ntng2,Smpdl3b,Slc13a3,Marcksl1,Clec4e,Il2rg,Tnf,Inpp5b,Abcb1a,Xkr8,Acsl1,Fut8,Ccrl2,Prrg4,Traf5,H60b,Lipe,Cd180,Acpp,Ly75,Atp10a,Gbgt1,Cxcl9,Rgs14,Psd4,Lrrc8c,Trem1,Hck,Rtp4,Cd55,Ppp2r1b,Rhoq,Jag1,Olr1,Fscn1,Kmo,Bst1,Pmepa1,Cd164,Phlpp1,Igtp,Layn,Spaca6,Rtn1,Cysltr2,Mgat1,Itga9,Cxcl10,Mtdh,Fgr,Sec24a,Adam19,Htr2b,Ptk2,Slc7a2,Tor1aip1,Tlr2,Dio2,Cd83,Cacna1d,Rnf139,Slc25a22,Clec2d,Chst11,Icosl,Sphk1,Golga3,Atp11a,Clec4n,Acp2,Ednrb,Rnf145,Hsd17b12,Fchsd2,Birc3,Slc2a1,Cd34,Tor1aip2,Dram1,Slc9a1,Ptgs2,Ptger4,Notch2,Ero1l,Dnajb2,Cers6,Tmem26,H2-Q7,Htr2a,Pikfyve,Vrk2,Psd,9930111J21Rik1,Gm4841,Cd200,Tmem67,Iigp1,Calcrl,Pdzd11,Clic5,Cd86,Tap2,Slc7a8,H2-T24,Stxbp1,Cpeb4,Ms4a6d,H2-Q6,Slc39a4,Abcc4,Pik3r6,Slc7a11,Slc49a4,Notch1,Tnfsf9,Tlr6,Plscr1,Prokr1,Cd69,Slc30a4,Cd300lf,Lpcat2,St3gal6,Dpy19l1,Pigv,Plaat3,Hilpda,Pkp4,Hspa1a,Slc31a2,Gcnt2,Rnf24,Gpr84,Icam1,Slamf9,Agrn,Cd82,Acvr1,Cox18,Slc48a1,Pik3cd,P2ry2,4932438A13Rik,Fzd1,Fpr1,Tnfsf15,H2-M2,Fndc3a |
| 5.864e-03 | -5.14 | endoplasmic reticulum part | cellular component | GO:0044432 | 622 | 59 | 20747 | 1409 |
Vrk2,F830016B08Rik,Rab19,H2-Q7,Tmem178,Pml,Pnpt1,Gm4951,Rhbdf2,Slc37a3,Gm5431,Iigp1,H2-Q4,Tmem67,P4ha1,9930111J21Rik1,Zc3h12a,Gm12185,Gm4841,Tap1,Ext1,H2-Q6,Rtn2,P4ha2,Tap2,Ifi47,Tgtp1,Rnaset2b,Tmtc2,Traf2,Sgms2,Dhrs9,Mtdh,Dst,Pigv,Igtp,Rtn1,Edn1,Plpp3,Irgm2,Cept1,Rab10,Rnf139,Ch25h,Rrbp1,Tor3a,Tgtp2,Itpr1,Pgap2,Rnaset2a,Trim13,Lnpk,Tapbp,Osbpl3,Dnajb2,Ero1l,Rsad2,Irgm1,Gramd1a |
| 5.883e-03 | -5.14 | TNFs bind their physiological receptors | REACTOME pathways | R-MMU-5669034 | 26 | 7 | 8608 | 757 |
Tnfsf9,Tnfrsf14,Tnfsf4,Tnfrsf8,Tnfsf15,Tnfsf8,Tnfrsf1b |
| 5.883e-03 | -5.14 | Generation of second messenger molecules | REACTOME pathways | R-MMU-202433 | 26 | 7 | 8608 | 757 |
H2-Aa,Evl,H2-Eb1,Lcp2,H2-Ab1,Nck1,Vasp |
| 5.883e-03 | -5.14 | Basigin interactions | REACTOME pathways | R-MMU-210991 | 26 | 7 | 8608 | 757 |
Slc7a5,Cav1,Slc16a3,Slc7a8,Slc7a11,Spn,Slc16a1 |
| 5.890e-03 | -5.13 | regulation of viral entry into host cell | biological process | GO:0046596 | 33 | 7 | 20694 | 1406 |
Cd74,Trim56,Trim30a,Nectin2,Ifitm1,Trim26,Trim21 |
| 5.890e-03 | -5.13 | regulation of vascular permeability | biological process | GO:0043114 | 33 | 7 | 20694 | 1406 |
Nr3c1,Il18,Angpt1,Ccl4,Abr,Adora2a,Ptprj |
| 5.890e-03 | -5.13 | negative regulation of signal transduction in absence of ligand | biological process | GO:1901099 | 33 | 7 | 20694 | 1406 |
Cx3cl1,Tnf,Il1b,Eya4,Sgk3,Cx3cr1,Pf4 |
| 5.890e-03 | -5.13 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological process | GO:2001240 | 33 | 7 | 20694 | 1406 |
Cx3cr1,Sgk3,Tnf,Eya4,Il1b,Cx3cl1,Pf4 |
| 5.890e-03 | -5.13 | regulation of B cell differentiation | biological process | GO:0045577 | 33 | 7 | 20694 | 1406 |
Slamf8,Tlr9,Syk,Prdm1,Il2rg,Stat5a,Mmp14 |
| 5.890e-03 | -5.13 | regulation of hydrogen peroxide-induced cell death | biological process | GO:1903205 | 33 | 7 | 20694 | 1406 |
Il10,Nr4a3,Glrx,Txn1,Hsph1,Hk3,Met |
| 5.890e-03 | -5.13 | icosanoid biosynthetic process | biological process | GO:0046456 | 33 | 7 | 20694 | 1406 |
Sphk1,Syk,Edn1,Cd74,Ptges,Ptgs2,Pla2g4a |
| 5.908e-03 | -5.13 | GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_UP | MSigDB lists | GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_UP | 155 | 22 | 15632 | 1249 |
Ripk3,Chd9,Tax1bp1,Fbxo4,Pde3b,Cflar,Sertad3,Slco3a1,Parp11,Ubash3b,Phyh,Phip,Usp25,Pml,Parp3,Parp12,Kdm5b,Fchsd2,Akt3,Ddit4,Sqstm1,Brwd3 |
| 5.908e-03 | -5.13 | GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_DN | 155 | 22 | 15632 | 1249 |
Cxcl1,Fscn1,Cd14,Rnf19b,Prrg4,Mmp9,Icam1,Clec5a,F11r,Tlr2,Ier3,Stat3,Pdlim7,Slc15a3,H2-Aa,Jag1,Cxcl2,Cpd,Tor3a,Gna15,Csf3r,Zyx |
| 5.908e-03 | -5.13 | MODULE_334 | MSigDB lists | MODULE_334 | 155 | 22 | 15632 | 1249 |
Zeb1,Gclm,Cish,Snx2,Cebpd,Ccng2,Dusp4,Crbn,Syk,Timp1,Hspa1a,Pfkfb3,Pilrb2,Pilrb1,Prkar2b,Sp110,Ifi35,Rnf139,Rhoh,Osgin2,Frmd4a,Cxcl10 |
| 5.917e-03 | -5.13 | TRAIL signaling | REACTOME pathways | R-MMU-75158 | 5 | 3 | 8608 | 757 |
Casp8,Tnfsf10,Cflar |
| 5.920e-03 | -5.13 | negative regulation of neuron differentiation | biological process | GO:0045665 | 260 | 29 | 20694 | 1406 |
Sema4c,Rap1gap2,Ifrd1,Pbx1,Cdk5r1,Zhx2,Cav1,Kremen1,Ednrb,Mdm2,Prag1,Il1b,Notch1,Il15ra,Ptk2,Dync1i2,Gfi1,Casz1,Mecp2,Jag1,Lrp4,Lpar1,Cd38,Sema3c,Plk2,Map4k4,Rapgef2,Katna1,Sema4a |
| 5.930e-03 | -5.13 | GO_EMBRYONIC_MORPHOGENESIS | MSigDB lists | GO_EMBRYONIC_MORPHOGENESIS | 520 | 58 | 15632 | 1249 |
Vegfc,Sec24b,Htr2b,Nr4a3,Kdm6b,Dusp5,Inhba,Mmp13,Fzd1,Vasp,Ext1,Fzd5,Mthfd1l,Gja1,Tshz1,Apaf1,Notch1,Pbx1,Tulp3,Hif1a,Zfp281,Intu,Hhex,Itga4,Hlx,Hdac1,Acvr1,Setdb2,Dusp1,Txnrd1,Lrp4,Lhx2,Rpgrip1l,Sema4c,Socs3,Mmp9,Itga5,Zeb1,Il10,Lmo4,Ptch1,Clic5,Col4a2,Sdc4,Abr,Chst11,Dusp4,Ift57,Phactr4,Edn1,Spry2,Dusp2,Mmp14,Ets2,Flt1,Itgav,Bcl2l11,Flrt3 |
| 5.938e-03 | -5.13 | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | MSigDB lists | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | 193 | 26 | 15632 | 1249 |
Cd55,Mthfd2,Phyh,Cd82,Arf4,Il1rn,Tcea1,Cdkn1a,Pfkl,Ppfibp2,Stip1,Gja1,S100a8,Casp4,Mmp13,Egr1,Ier2,Psme1,Cx3cl1,Sdc4,Klf3,Nfkbia,Fos,Myc,Abcb1a,Casp3 |
| 5.980e-03 | -5.12 | GSE42088_2H_VS_24H_LEISHMANIA_INF_DC_UP | MSigDB lists | GSE42088_2H_VS_24H_LEISHMANIA_INF_DC_UP | 174 | 24 | 15632 | 1249 |
Bst1,Zfp36,Slc9a1,Klf2,Rnaset2a,Cd86,Pdk3,Tor3a,Rnaset2b,Mppe1,Phyh,Tgfbi,Hmox1,Nod2,Rab11fip1,Cd302,Csf3r,Fos,Nr4a1,Crbn,Cnn2,Tspo,Cd14,Myd88 |
| 5.980e-03 | -5.12 | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | 174 | 24 | 15632 | 1249 |
Plekhn1,Ptprj,Clec5a,Sap30,Tlr1,Bst1,Adora2a,Eif4g2,Cnp,Gna15,Pid1,Lcp2,P2ry2,Hvcn1,Tnfaip3,Spata13,St3gal6,Mdn1,Tmem171,4932438A13Rik,Hsph1,Src,Psip1,Dnaja1 |
| 5.980e-03 | -5.12 | GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP | 174 | 24 | 15632 | 1249 |
Ogfrl1,Aebp2,Cox17,D1Ertd622e,Spry2,Zyx,Gadd45b,Sgcb,Irs2,Nupr1,Snx2,Wars,Rilpl1,Casp4,Rrs1,Tnfrsf1b,Ppp1r15b,Ttc9c,Hsd17b12,Hcls1,Pdzd11,Fam111a,Uchl1,Larp1 |
| 5.980e-03 | -5.12 | GSE27786_LSK_VS_CD4_TCELL_DN | MSigDB lists | GSE27786_LSK_VS_CD4_TCELL_DN | 174 | 24 | 15632 | 1249 |
Fgl2,Rictor,Vasp,Ikzf1,Nr3c1,Fcgr2b,Ppp2r5a,Ppp4r2,Daam1,Eno1,Plekha2,Nlrc5,Klf3,Sesn3,Tsku,Glrx,Tap1,Osbpl3,Zbp1,Ddx58,Grina,Spata13,Slc30a1,Parp3 |
| 5.980e-03 | -5.12 | GSE27786_BCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_BCELL_VS_NKTCELL_DN | 174 | 24 | 15632 | 1249 |
Spry2,Rnf24,Abcc5,Ccdc88b,Crim1,Tmem176b,Usp25,Agtrap,St3gal6,Slc7a5,Plscr1,Mmd,Hk1,Osm,Med21,Jak2,Rgs1,Ikbke,Glrx,Zhx2,Smox,Atp10a,Mppe1,Ttc39b |
| 5.980e-03 | -5.12 | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_UP | MSigDB lists | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_UP | 174 | 24 | 15632 | 1249 |
Cxcl2,Cd69,Nfkbid,Dusp2,Zfp36,Htra1,Btg2,Osm,Fosb,Il10,Ppp1r15a,Fos,Dusp1,Pde4b,Ahr,Cxcl1,Nlrp3,Ier3,Cyth3,Filip1l,Egr1,Socs3,Malt1,Ier2 |
| 5.980e-03 | -5.12 | GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_UP | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_UP | 174 | 24 | 15632 | 1249 |
Inpp1,Tax1bp1,Fscn1,Pkp4,Rtn1,Stat1,Max,Ier3,Gpd2,Fzd1,Ednrb,Ankib1,Bmp2,Gng11,Pml,Pikfyve,Tpx2,Fam133b,Cycs,Ccnd1,Apobec3,Plekha5,Dusp1,Jun |
| 5.980e-03 | -5.12 | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | 174 | 24 | 15632 | 1249 |
Slc48a1,Pbx1,Gpc1,Cd14,Bfar,Rtp4,Slfn8,B3gnt5,Ift57,Mlkl,Cst7,Rgs1,Slfn9,Trafd1,Esd,Socs3,Atp10a,Ttc39b,Trib1,Phlda1,Stx6,Sco1,Mcm9,Tap2 |
| 5.982e-03 | -5.12 | OCT1_01 | MSigDB lists | OCT1_01 | 232 | 30 | 15632 | 1249 |
Jarid2,Dusp6,Sesn3,Rel,Pdgfrb,Lmo4,Slc25a12,Hivep3,Csf3,Ppp2r3a,Egln3,Adora2a,Pim2,Rcan1,Gpr85,Lyn,H3f3b,Zhx2,Slc7a11,Mtus1,Cited2,Tcf4,Egr2,Ccnd1,Cpd,Mid1,Bcor,Cd180,Lipg,Pbx1 |
| 5.989e-03 | -5.12 | response to gamma radiation | biological process | GO:0010332 | 50 | 9 | 20694 | 1406 |
Myc,Mdm2,Atm,Dcun1d3,Cdkn1a,Sod2,Pml,Tlk2,Egr1 |
| 6.000e-03 | -5.12 | Caspase activation via extrinsic apoptotic signalling pathway | REACTOME pathways | R-MMU-5357769 | 20 | 6 | 8608 | 757 |
Traf2,Casp8,Casp3,Fas,Cflar,Tnfsf10 |
| 6.000e-03 | -5.12 | CTLA4 inhibitory signaling | REACTOME pathways | R-MMU-389513 | 20 | 6 | 8608 | 757 |
Cd86,Ppp2r1b,Cd80,Ppp2r5a,Src,Lyn |
| 6.009e-03 | -5.11 | glutamine family amino acid metabolic process | biological process | GO:0009064 | 59 | 10 | 20694 | 1406 |
Asns,Arg2,Gfpt1,Mecp2,Gclm,Nos2,Adhfe1,Gclc,Phgdh,Ass1 |
| 6.019e-03 | -5.11 | BUTYPHLNCDUF | prints domains | PR01407 | 53 | 9 | 5821 | 374 |
Trim30a,Trim12c,Trim34a,Mid1,Trim21,Trim30d,Rnf135,Trim26,Trim14 |
| 6.027e-03 | -5.11 | sensory organ morphogenesis | biological process | GO:0090596 | 295 | 32 | 20694 | 1406 |
Abr,Ttc39c,Jag1,Cited2,Phactr4,Pdgfb,Flt1,Kdr,Hif1a,Casz1,Eya4,Hdac1,Prdm1,Stat3,Ikzf1,Zhx2,Notch2,Spry2,Nr4a3,Tdrd7,Tsku,Triobp,Tshz1,Edn1,Gfi1,Clic5,Zeb1,Ppp2r3a,Sec24b,Myc,Fzd5,Slc4a7 |
| 6.027e-03 | -5.11 | Interferon | pfam domains | PF00143 | 24 | 6 | 18711 | 1348 |
Ifna2,Ifna5,Ifna1,Ifna6,Ifnb1,Ifna4 |
| 6.027e-03 | -5.11 | Signaling by Leptin | REACTOME pathways | R-MMU-2586552 | 221 | 31 | 8608 | 757 |
Angpt1,Psme2b,Ppp2r5a,Irs2,Src,Spred1,Kitl,Socs3,Pdgfb,Ppp2r1b,Jak2,Map2k1,Ksr1,Il2rg,Pdgfrb,Psmd10,Psme2,Psma6,Psmb10,Stat3,Ptk2,Met,Psmb8,Psme1,Dusp5,Psmb6,Dusp6,Rapgef2,Stat5a,Rasgrp1,Psmb9 |
| 6.037e-03 | -5.11 | GO_EXTRINSIC_COMPONENT_OF_MEMBRANE | MSigDB lists | GO_EXTRINSIC_COMPONENT_OF_MEMBRANE | 242 | 31 | 15632 | 1249 |
Nsmaf,Lyn,Pik3cd,Zc3h12a,Gng4,Ptk2,Gng12,Plaur,Rgs1,Mitd1,Jak2,Golga3,Pik3r6,Gna15,Snx10,Tyk2,Bst1,Snx2,Fgr,Prnp,Cyth3,Pml,Hck,Gng11,Eno1,Syk,Pik3r5,Bcl2l11,Src,Ezr,Errfi1 |
| 6.044e-03 | -5.11 | GUO_TARGETS_OF_IRS1_AND_IRS2 | MSigDB lists | GUO_TARGETS_OF_IRS1_AND_IRS2 | 92 | 15 | 15632 | 1249 |
Pde7b,Flnb,Cacybp,Slc7a2,Dnaja1,Hsph1,Tnfrsf1b,Gch1,Vegfc,Dnajb2,Actb,Rbms1,Rcan1,Rnd1,Ifi35 |
| 6.044e-03 | -5.11 | GO_REGULATION_OF_CELL_MATRIX_ADHESION | MSigDB lists | GO_REGULATION_OF_CELL_MATRIX_ADHESION | 92 | 15 | 15632 | 1249 |
Acvrl1,Mmp14,Slc9a1,Csf1,Bcl6,Serpine1,Plekha2,Src,Vegfc,Kdr,Thbs1,Sdc4,Plau,Ptprj,Ptk2 |
| 6.053e-03 | -5.11 | GO_HEXOSE_METABOLIC_PROCESS | MSigDB lists | GO_HEXOSE_METABOLIC_PROCESS | 146 | 21 | 15632 | 1249 |
Pgk1,Pfkl,Hk3,Pfkfb3,Irs2,Gpd2,Pgm1,Tpi1,Oas1g,Atf3,Pcx,Hk2,Oas1a,Slc25a12,Fut8,Serp1,Eno1,Hk1,Pdk3,Eno2,Tnf |
| 6.053e-03 | -5.11 | GSE4984_GALECTIN1_VS_LPS_STIM_DC_UP | MSigDB lists | GSE4984_GALECTIN1_VS_LPS_STIM_DC_UP | 146 | 21 | 15632 | 1249 |
Trim13,Phyh,Mppe1,Ddx58,Sema4c,Lrch3,Arl5c,Usp25,Tlr6,Filip1l,Zhx2,Elmod2,Serpinb2,Dse,Asah2,Vps54,Plekhf2,Psd4,Dtnb,Vasp,Trim14 |
| 6.074e-03 | -5.10 | MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | MSigDB lists | MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | 252 | 32 | 15632 | 1249 |
Rnf14,Fzd1,Jag1,Usp12,Sirt1,Ep400,Nmi,Pdgfb,Phf6,Dnaja2,Fndc3a,Dck,Lrrc8c,Glrx,Igf2bp2,Vegfc,Ppp2r1b,Clcn7,Cflar,Birc2,Slc2a1,Nlrc4,Txnrd1,Hsph1,Vcan,Myc,D1Ertd622e,Spry2,Cdk5r1,Zfp281,Stau1,Crlf3 |
| 6.077e-03 | -5.10 | GO_MANGANESE_ION_BINDING | MSigDB lists | GO_MANGANESE_ION_BINDING | 43 | 9 | 15632 | 1249 |
Me1,Fam20c,Idi1,Lap3,Dcp2,Mppe1,Pim1,Dyrk2,Sod2 |
| 6.077e-03 | -5.10 | GNF2_SELL | MSigDB lists | GNF2_SELL | 43 | 9 | 15632 | 1249 |
Myd88,Hcls1,Rnaset2b,Junb,Casp1,Rnaset2a,Sell,Lyn,Casp4 |
| 6.093e-03 | -5.10 | negative regulation of hydrolase activity | biological process | GO:0051346 | 438 | 44 | 20694 | 1406 |
Ppp1r15a,Cst7,C3,Serpinb2,Birc2,Serpinb9,Spry2,Serpine1,Cdkn2d,Ppp1r14b,Plaur,Nr4a1,Birc3,Rnf34,Sh3bp4,Phactr4,Serpina3g,Tnf,Adora2a,Rffl,Sirt1,Mmp9,Mdm2,Serpinb9b,Cnn3,Prdx5,F11r,Timp1,Spint2,Ahr,Tnfsf14,Src,Hspa1b,Thbs1,Marf1,Il6,Slpi,Spred1,Serpina3f,Ptgs2,Serpinb6b,Lrch1,Cflar,Bcl2a1d |
| 6.094e-03 | -5.10 | LIF_OSM | prosite domains | PS00590 | 2 | 2 | 13278 | 1037 |
Osm,Lif |
| 6.094e-03 | -5.10 | MARCKS_2 | prosite domains | PS00827 | 2 | 2 | 13278 | 1037 |
Marcks,Marcksl1 |
| 6.094e-03 | -5.10 | MARCKS_1 | prosite domains | PS00826 | 2 | 2 | 13278 | 1037 |
Marcksl1,Marcks |
| 6.094e-03 | -5.10 | INTERLEUKIN_6 | prosite domains | PS00254 | 2 | 2 | 13278 | 1037 |
Il6,Csf3 |
| 6.109e-03 | -5.10 | mouse chr10|10 A3 | chromosome location | mouse chr10|10 A3 | 37 | 7 | 24173 | 1464 |
Reps1,Mtfr2,Raet1e,C920009B18Rik,Abracl,Pde7b,H60b |
| 6.112e-03 | -5.10 | cellular catabolic process | biological process | GO:0044248 | 1466 | 124 | 20694 | 1406 |
Cnp,Psmb8,S100a8,Dio2,Klhl25,Dcp2,Arrdc4,Gtpbp2,Psmb9,Pnpt1,Trim12a,Usp42,Apobec3,Mmp13,Rnf34,Znrf3,Hdc,Enpp4,Kmo,Gda,Rnf19b,Cop1,Zfp36,Dcp1a,Lnpep,Dtx3l,Pde5a,Rubcnl,Esd,Dnajb2,Birc2,Xrn1,Tent2,Rnaset2a,Aoah,Smg7,Ldlr,Hap1,Peli1,Tut7,Smpdl3b,Rnf14,Psma6,Nos2,Gpc1,Irgm2,Phyh,Lrp4,Arg2,Usp12,1600014C10Rik,Usp25,Chmp4b,Rnf139,Zc3h12a,Spsb1,Dnase1l3,Optn,Hmox1,Tnfaip3,Lipe,Crbn,Gsta3,Prdx5,Znrf1,Uba7,Asah2,Armc8,Pla2g4a,Ago3,Pml,Casp8,Noct,Irgm1,Rnf19a,Prdx1,Bfar,Fnbp1l,Magohb,Rffl,Smox,Cnot4,Tha1,Psmb10,Psmb6,Oas2,Lipg,Bnip3,Uchl1,Zhx2,Tmem67,Ctsc,Samhd1,Isg20,Ubr4,Tpi1,Fbxo4,Slfn8,Ube2l6,Sat1,Ankib1,Mgat1,Acsl1,Atm,Tent4a,Upp1,Isg15,Tet2,Dram1,Polr2g,Irf8,Txnrd1,Trim13,Sirt1,Arel1,Mdm2,Keap1,Trim30a,Adhfe1,Il4i1,Cemip2,Helz2,Usp18,Sqstm1 |
| 6.124e-03 | -5.10 | organic substance transport | biological process | GO:0071702 | 1868 | 154 | 20694 | 1406 |
Tap1,Isg15,Hhex,Acsl5,Slc2a1,Slc7a2,Arf4,Lrrc8c,Parp11,Abcc5,Spire1,Slc7a8,Slc15a3,Atp11a,Cav1,Lyn,Slc7a11,Gja1,Itgav,Rtp4,Tbc1d13,Rab32,Stoml1,Rrbp1,Plek,Trem1,Rab9,Plscr1,Grk3,Cox18,Stard7,Atp11b,G3bp2,Acsl1,Ap3m2,Il6,Kpna3,Il1rn,Traf3ip2,Slc28a2,Fabp3,Cd74,Slc4a7,Lipg,Tbc1d1,Slc25a12,Ift22,Rab10,Rabgef1,Slc37a3,Slc16a1,Calcrl,Notch2,Slc7a5,Phip,Igf2bp2,Dennd2a,Stxbp3,Msr1,Arl5b,Pla2g4a,Abcc1,Cdkn1a,Pml,Slc44a1,Rab20,Rtn2,Stra6l,Serp1,Ift57,Arl5c,Slc13a3,Slc16a3,Snx2,Rffl,Magohb,Stxbp1,Egr2,Ric1,Syk,Osbpl3,Ranbp2,Chmp4b,Nlrp3,Notch1,Gramd1a,Plekhf2,Apba1,Optn,Tomm70a,Pou2f2,Abcc4,Adar,Fam53c,Tlr2,Inhba,Tlr6,Lcp2,Nlrc4,Slco3a1,Rab19,Sec24a,Ldlr,Rrs1,Stx11,Nfkbie,Hap1,Snx10,Aftph,Myo1b,Stat3,Nxf1,Rhbdf2,Arl4a,Nos2,Rilpl1,Slc29a3,Slc25a25,Atp10a,Rab3ip,Rnf19b,Slc25a22,Zfp36,Svbp,Vps54,Myc,Dtx3l,Slc48a1,Dennd1b,Tap2,Nod2,Stx6,Edn1,Stau1,Xkr8,Dio2,Rab21,D1Ertd622e,Ezr,Stard5,Arrdc4,Nfkbia,Pdpn,Aim2,Ap3b1,Pnpt1,Fchsd2,Tspo,Rab11fip1,Ehd1,Kif5c,Mcoln2,Mecp2,Abcb1a |
| 6.139e-03 | -5.09 | Apc (APC, WNT signaling pathway regulator) | protein interactions | 11789 | 49 | 11 | 7778 | 753 |
Ccnd1,Ptges,Ptgs2,Nos2,Pla2g4a,Plau,Sat1,Il6,Myd88,Myc,Jun |
| 6.164e-03 | -5.09 | C-C chemokine binding | molecular function | GO:0019957 | 25 | 6 | 20217 | 1400 |
Ccr3,Ccr1,Cx3cr1,Ccrl2,Xcr1,Zfp36 |
| 6.164e-03 | -5.09 | chemokine receptor activity | molecular function | GO:0004950 | 25 | 6 | 20217 | 1400 |
Cx3cr1,Ccr1,Ccr3,Gpr35,Ccrl2,Xcr1 |
| 6.164e-03 | -5.09 | G protein-coupled chemoattractant receptor activity | molecular function | GO:0001637 | 25 | 6 | 20217 | 1400 |
Ccr3,Ccr1,Cx3cr1,Ccrl2,Xcr1,Gpr35 |
| 6.171e-03 | -5.09 | GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 137 | 20 | 15632 | 1249 |
Jun,Bcl6,Arhgef3,Plk2,Cyfip1,Dbnl,Ksr1,Phactr4,Rasgrp1,Rhou,Rapgef2,G3bp2,Mapkapk2,Crkl,Cdc42ep4,Ralgds,Cdc42ep2,Rap2c,Rras2,Cdkn1a |
| 6.171e-03 | -5.09 | regulation of DNA biosynthetic process | biological process | GO:2000278 | 118 | 16 | 20694 | 1406 |
Dusp1,Gja1,Pdgfb,Atm,Ahr,Src,Fbxo4,Acvrl1,Pdgfrb,Dcp2,Myc,Smg7,Pml,Parp3,Cdkn1a,Dach1 |
| 6.171e-03 | -5.09 | activation of MAPK activity | biological process | GO:0000187 | 118 | 16 | 20694 | 1406 |
Met,Mlkl,Thbs1,Gdf15,Bmp2,Il1b,Map2k1,Map2k4,Cd74,Syk,Crkl,Tnf,Mdfic,Lpar1,Mul1,Ripk2 |
| 6.182e-03 | -5.09 | GSE17721_POLYIC_VS_PAM3CSK4_0.5H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_0.5H_BMDC_DN | 184 | 25 | 15632 | 1249 |
Kat2b,Agtrap,Rars,Usp25,Rbl1,Me1,Phldb1,Cst7,Rin2,Fgl2,Acvr1,C1ra,Ccl2,Chic2,Mafg,Nr4a3,Mtmr14,Vrk2,Ralgds,Cav1,Tshz1,Parp12,Oas2,Trim26,Sap30 |
| 6.182e-03 | -5.09 | GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 184 | 25 | 15632 | 1249 |
Pde7b,Stx11,Stx6,Ext1,Plod2,Lad1,Asns,Jdp2,Nampt,Cd200,Dusp5,Ptgir,Ppa1,Smox,Kdm6b,Cpd,Dhx58,Phgdh,Oaf,Srm,Gadd45b,Stat5a,Relb,Cd83,Magohb |
| 6.199e-03 | -5.08 | plasma membrane bounded cell projection | cellular component | GO:0120025 | 2222 | 180 | 20747 | 1409 |
Bnip3,Syne2,Sirt1,Cyth3,Ptprj,Tmod3,Kcna3,Clic4,Flrt3,Cx3cr1,Cnp,Cdk5r1,Fos,Grk3,Casp4,Myadm,Eno1,Igf1r,Atp2b4,Ntng2,Daam1,Tnfrsf1b,Eno2,Myo1b,Hdc,Prkar2b,Spn,Nox1,Mtmr14,Dync1h1,Src,Mark2,Angpt1,Phactr4,Xrn1,Pde4b,Orai2,Arf4,D1Ertd622e,Plek,Spata13,Cd40,Kif5c,Hdac1,Homer1,Adgrl2,Optn,Tpx2,Itgav,Cd302,Tulp3,Ift22,Ccl2,Lpar1,Map2k4,Stau1,Asap3,Mul1,Casp1,Myo10,Nr3c1,Map2k1,Fcgr2b,Igsf8,Pdgfb,Intu,Txn1,Atp6v1d,Myc,Acvrl1,Phlpp2,Rap1gap2,Pdpn,Itpr1,Mosmo,Met,Fas,Nlgn2,Slc4a7,Ift57,Hap1,Cenpj,Plk3,Rab3ip,Dst,Scn1b,Flnb,Uchl1,Abcc4,Rpgrip1l,Slc7a11,Casp8,Actb,Glrx,Cpeb4,Stxbp1,Cd200,Tmem67,Clic5,Psd,Rhoc,Ldha,Cnn3,Sqstm1,Itga5,Htr2a,Pdlim7,Nqo1,Ddx58,Rab21,Fzd1,Dock4,Cx3cl1,Cav1,Hk1,Kitl,Agrn,Adora2a,Plk2,Palld,Rab10,Ass1,Scimp,Hif1a,Prnp,Ezr,Cyfip1,Phlpp1,Eif4g2,Itga4,Daxx,Bst1,Ptch1,Lrp4,Rapgef2,Apba1,Fscn1,Rgs14,Psd4,Stat1,Flrt2,Rilpl1,Sipa1l1,Lrp8,Vasp,Igsf9,Evl,Ctla2a,Adrb2,Acpp,Katna1,Triobp,Kif3c,Abcb1a,Kcnj2,Ero1l,Antxr1,Vcam1,Cacybp,Notch2,Micall2,Ptgs2,Ptger4,Fchsd2,Ehd1,Acp2,Max,Dock10,Rac3,Nrp2,Sphk1,Dbnl,Carmil1,Kdr,Cacna1d,Fgr,P2ry12,Htr2b,Ptk2,Nfkb1 |
| 6.204e-03 | -5.08 | Calponin_repeat | interpro domains | IPR000557 | 6 | 3 | 19984 | 1430 |
Tagln,Cnn3,Cnn2 |
| 6.204e-03 | -5.08 | Liprin | interpro domains | IPR029515 | 6 | 3 | 19984 | 1430 |
Ppfibp2,Ppfibp1,Ppfia3 |
| 6.204e-03 | -5.08 | PAP_assoc | interpro domains | IPR002058 | 6 | 3 | 19984 | 1430 |
Tent4a,Tut7,Tent2 |
| 6.204e-03 | -5.08 | TNF | interpro domains | IPR006053 | 6 | 3 | 19984 | 1430 |
Tnf,Tnfsf14,Tnfsf15 |
| 6.204e-03 | -5.08 | TNF_rcpt--assoc_TRAF | interpro domains | IPR012227 | 6 | 3 | 19984 | 1430 |
Traf2,Traf5,Traf1 |
| 6.207e-03 | -5.08 | Kit Receptor Signaling Pathway | WikiPathways | WP407 | 67 | 15 | 4813 | 540 |
Map2k1,Stap1,Stat5a,Stat1,Kitl,Hck,Cish,Lyn,Spred1,Socs1,Jak2,Fgr,Src,Crkl,Stat3 |
| 6.255e-03 | -5.07 | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | MSigDB lists | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | 128 | 19 | 15632 | 1249 |
Sema3c,Lap3,Eno1,Agrn,Phactr4,Gsr,Cp,Pnp2,Cx3cl1,Psmb6,Tpi1,Col18a1,Ldha,Pgk1,Me1,Prdx1,Actb,Vcam1,Sdc4 |
| 6.284e-03 | -5.07 | RODRIGUES_DCC_TARGETS_DN | MSigDB lists | RODRIGUES_DCC_TARGETS_DN | 110 | 17 | 15632 | 1249 |
Ccnd2,Pim1,Nupr1,Klf7,Ahr,Myo10,Glrx,Gfpt1,Psmb9,Bcl6,Tank,Klf6,Kdm5b,Mecp2,Mid1,Ccng2,Rasgrp1 |
| 6.287e-03 | -5.07 | GO_REGULATION_OF_GTPASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_GTPASE_ACTIVITY | 618 | 67 | 15632 | 1249 |
Spry2,Ccl2,Rin2,Psd,Rapgef5,Agrn,Ccl12,Dock4,Jun,Trip10,Cdc42ep2,Angpt1,Nck1,Abr,Cyth3,Ccl22,Cx3cl1,Irs2,Rictor,Rasgrp1,Rap1gap2,Rabgef1,Plekhg1,Adap2,Arf4,Jak2,Ccl4,Rgs1,Tagap,Ptk2,Ptgir,Dennd2a,Tbc1d1,Dennd1b,Errfi1,Arhgap26,Dock10,P2ry12,Rgs14,Arhgef3,Bcl6,Cd40,Rgs3,Rab3ip,Ccl3,Asap3,Rhoh,F11r,Icam1,Spata13,Inpp5b,Pdgfb,Sh3bp4,Rapgef2,Tbc1d13,Rgl1,Ccl5,Psd4,Sipa1l1,Pdgfrb,Elmod2,Kitl,Ralgds,Pkp4,Htr2b,Cdc42ep4,Il2rg |
| 6.288e-03 | -5.07 | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 223 | 29 | 15632 | 1249 |
Tnf,Ccl12,Mdm2,Rbpms,Micall2,Il6,Ddx58,Sphk1,Cdk5r1,Plk3,Plagl2,Tnfsf14,Fzd5,Rnf31,Csf3,Rhou,Slc9a1,Ptgs2,Il18,Tlr2,Il12b,Tlr3,Tlr9,Zc3h12a,Stard7,Il1b,Jak2,Hcls1,Bambi |
| 6.289e-03 | -5.07 | GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | 22 | 6 | 15632 | 1249 |
Cflar,Bmp2,Hdac1,Daxx,Notch1,Cxcl10 |
| 6.289e-03 | -5.07 | GO_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION | MSigDB lists | GO_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION | 22 | 6 | 15632 | 1249 |
Tnfsf14,Cxcl10,Il4ra,Cflar,Ehd1,Gdf15 |
| 6.289e-03 | -5.07 | GO_ARF_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | GO_ARF_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 22 | 6 | 15632 | 1249 |
Arf4,Nck1,Psd4,Psd,Cyth3,Trip10 |
| 6.289e-03 | -5.07 | BIOCARTA_IL2_PATHWAY | MSigDB lists | BIOCARTA_IL2_PATHWAY | 22 | 6 | 15632 | 1249 |
Stat5a,Syk,Fos,Jun,Map2k1,Il2rg |
| 6.289e-03 | -5.07 | BILANGES_SERUM_SENSITIVE_VIA_TSC1 | MSigDB lists | BILANGES_SERUM_SENSITIVE_VIA_TSC1 | 22 | 6 | 15632 | 1249 |
Junb,Rnd3,Tuba4a,Egr1,Phlda1,Dusp4 |
| 6.289e-03 | -5.07 | BIOCARTA_VIP_PATHWAY | MSigDB lists | BIOCARTA_VIP_PATHWAY | 22 | 6 | 15632 | 1249 |
Prkar2b,Egr2,Myc,Nfkb1,Egr3,Nfkbia |
| 6.289e-03 | -5.07 | LA_MEN1_TARGETS | MSigDB lists | LA_MEN1_TARGETS | 22 | 6 | 15632 | 1249 |
Azi2,Casp8,Snx10,Nupr1,Itga5,Adam19 |
| 6.289e-03 | -5.07 | GO_G_PROTEIN_COUPLED_CHEMOATTRACTANT_RECEPTOR_ACTIVITY | MSigDB lists | GO_G_PROTEIN_COUPLED_CHEMOATTRACTANT_RECEPTOR_ACTIVITY | 22 | 6 | 15632 | 1249 |
Cmklr1,Ccr3,Ccrl2,Xcr1,Cx3cr1,Ccr1 |
| 6.289e-03 | -5.07 | GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_6 | MSigDB lists | GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_6 | 22 | 6 | 15632 | 1249 |
Pid1,St3gal6,Stat3,Ccl12,Nfkb1,Il6 |
| 6.289e-03 | -5.07 | GO_POSITIVE_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION | 22 | 6 | 15632 | 1249 |
Cd86,Il12rb1,Il18,Il12b,Tnfsf4,Icosl |
| 6.289e-03 | -5.07 | KEGG_DORSO_VENTRAL_AXIS_FORMATION | MSigDB lists | KEGG_DORSO_VENTRAL_AXIS_FORMATION | 22 | 6 | 15632 | 1249 |
Notch1,Etv6,Ets2,Map2k1,Spire1,Notch2 |
| 6.289e-03 | -5.07 | GO_PODOSOME | MSigDB lists | GO_PODOSOME | 22 | 6 | 15632 | 1249 |
Palld,Dbnl,Fscn1,Vcam1,Kif9,Rhou |
| 6.296e-03 | -5.07 | UDAYAKUMAR_MED1_TARGETS_UP | MSigDB lists | UDAYAKUMAR_MED1_TARGETS_UP | 119 | 18 | 15632 | 1249 |
Rhoq,Stx6,Psat1,Ccnj,Eif2ak2,Slc16a3,Gch1,Higd1a,Asns,Slc16a1,Pfkl,Me1,Mtdh,Malt1,Lrp8,Dcp2,Sdc1,Nsmaf |
| 6.300e-03 | -5.07 | Neomycin, kanamycin and gentamicin biosynthesis | KEGG pathways | ko00524 | 5 | 3 | 7931 | 713 |
Hk1,Hk3,Hk2 |
| 6.300e-03 | -5.07 | Neomycin, kanamycin and gentamicin biosynthesis | KEGG pathways | mmu00524 | 5 | 3 | 7931 | 713 |
Hk1,Hk3,Hk2 |
| 6.303e-03 | -5.07 | maintenance of protein location | biological process | GO:0045185 | 108 | 15 | 20694 | 1406 |
Hk2,Nfkbib,Keap1,Hk1,Psmd10,Srgn,Tmsb10,Syne2,Tspo,Cav1,Nfkbia,Txn1,Pml,Lgals9,Morc3 |
| 6.308e-03 | -5.07 | MODULE_241 | MSigDB lists | MODULE_241 | 67 | 12 | 15632 | 1249 |
Cd14,Ier3,Dusp2,Tlr1,Piezo1,Aoah,Ccr1,Sod2,Gdf15,Gna15,Trip10,Mgat1 |
| 6.312e-03 | -5.07 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | 437 | 50 | 15632 | 1249 |
Fam162a,Rnaset2b,Sh3bgrl2,Tmem67,Ust,Trib1,Egr3,Syne2,Kctd12,St3gal5,Ednrb,Kif9,Lpcat2,Kat2b,Papss2,Dtwd1,Egr1,Sdc2,Tmem171,Slc44a1,Fos,Flrt3,Dio2,Snn,Prkx,Phyh,St3gal1,Fzd1,Rilpl1,Higd1a,Rnaset2a,Slc7a8,Csrp1,Psd4,Pbx1,Smg7,Hhex,Marcksl1,Lztfl1,Glipr2,Rbpms,Cebpd,Tbc1d1,Mdn1,Egr2,Mtus1,Itpr1,Tcf4,Cd302,Parp8 |
| 6.324e-03 | -5.06 | PAP_assoc | pfam domains | PF03828 | 6 | 3 | 18711 | 1348 |
Tent2,Tent4a,Tut7 |
| 6.324e-03 | -5.06 | Calponin | pfam domains | PF00402 | 6 | 3 | 18711 | 1348 |
Cnn3,Cnn2,Tagln |
| 6.328e-03 | -5.06 | regulation of epithelial to mesenchymal transition | biological process | GO:0010717 | 88 | 13 | 20694 | 1406 |
Bambi,Il6,Vasn,Jag1,Rgcc,Pdpn,Glipr2,Gcnt2,Notch1,Il1b,Acvr1,Bmp2,Phldb1 |
| 6.328e-03 | -5.06 | positive regulation of muscle cell differentiation | biological process | GO:0051149 | 88 | 13 | 20694 | 1406 |
Tnfsf14,Hopx,Ehd1,Il4ra,Sod2,Edn1,Cxcl9,Mmp14,Trip10,Sirt1,Nr3c1,Gdf15,Ccl8 |
| 6.328e-03 | -5.06 | interleukin-1 receptor binding | molecular function | GO:0005149 | 18 | 5 | 20217 | 1400 |
Il1b,Myd88,Tlr9,Il1a,Il1rn |
| 6.345e-03 | -5.06 | EGF | pfam domains | PF00008 | 65 | 11 | 18711 | 1348 |
Vcan,Plat,Jag1,Notch2,Notch1,F10,Sele,Agrn,Ltbp2,Ptgs2,Vasn |
| 6.371e-03 | -5.06 | GO_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY | 51 | 10 | 15632 | 1249 |
Ppp1r15a,Pdgfrb,Tnf,Eif2ak2,Ppp6r1,Ppp2r2a,Ppp2r3a,Jak2,Ppp2r5a,Ppp2r1b |
| 6.375e-03 | -5.06 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP | 156 | 22 | 15632 | 1249 |
P2ry13,Bcl6,Psmb9,Apobec3,Nlrc5,Ezr,Nr4a1,Fgl2,Ifi44,Mpp7,Tle3,Klf7,Fcgr1,Lmo4,Klf2,Il12rb1,Rcsd1,Nr4a3,Ptgs2,Mppe1,Rcl1,Prkx |
| 6.375e-03 | -5.06 | GSE22886_IGA_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE22886_IGA_VS_IGM_MEMORY_BCELL_UP | 156 | 22 | 15632 | 1249 |
Maff,Stx11,Slc25a12,Psat1,Atp6v1d,Hopx,Daam1,Cd86,Prkar2b,Dyrk2,Il13ra1,Xkr8,Arid5b,Gclm,Arhgap26,Cst7,Pik3r5,Klf7,Atp2b4,Rars,Fas,Aim2 |
| 6.375e-03 | -5.06 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN | 156 | 22 | 15632 | 1249 |
Ppp2r2a,Trem1,Tax1bp1,Rbm43,Rbms1,Rab20,Sema4a,Stat2,Upp1,Ptgs2,Phf6,Tlr3,Prdm1,Rnf19b,Tdrd7,Usp12,Slc7a5,Trim21,P2ry2,P2ry13,P2ry12,Sco1 |
| 6.421e-03 | -5.05 | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | 175 | 24 | 15632 | 1249 |
Xaf1,Mfap3l,Rel,Tnfsf10,Tax1bp1,Chd9,Acsl5,Rbms1,Esd,Kpna3,Tnfsf4,Dennd1b,Aftph,Stat3,Ap3b1,Casp1,Parp8,Klf6,Tank,D16Ertd472e,Sav1,Atp2b4,Klf7,Papss2 |
| 6.421e-03 | -5.05 | GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_DN | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_DN | 175 | 24 | 15632 | 1249 |
Tnf,Hsph1,Tagln,Cd40,Zyx,Phgdh,Mmp14,S1pr2,Cx3cl1,Cd34,Slc16a1,Bmp2,Klf7,Fcgr4,Ccne1,Irf8,Il10,Lcp2,Ogfr,Ppp2r3a,Max,Ell2,Kif5c,Ppp2r1b |
| 6.421e-03 | -5.05 | GSE27786_NKCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_NKCELL_VS_ERYTHROBLAST_UP | 175 | 24 | 15632 | 1249 |
Cd86,Pde4b,Ankib1,Tbc1d13,Trim14,Zc3h7a,Caml,Plscr1,Stxbp3,Asb13,Ttc39b,Ppa1,Hmox1,5430427O19Rik,Cmklr1,Ikbke,Acpp,Axl,Trmt1l,Cox17,B3gnt5,Irf2,Tlr6,Rhoh |
| 6.421e-03 | -5.05 | GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_DN | MSigDB lists | GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_DN | 175 | 24 | 15632 | 1249 |
Smpdl3b,Rnf19a,H2-Aa,Zfp36,Scn1b,Hopx,Gja1,Rgl1,Tagap,Pcdh7,Arid5b,Lpar1,Chst11,Egr2,Slc15a3,Slc39a4,Ccr3,Zyx,Timp1,Slc7a11,Stat5a,Slc48a1,Tspo,Atp11a |
| 6.423e-03 | -5.05 | MODULE_291 | MSigDB lists | MODULE_291 | 59 | 11 | 15632 | 1249 |
Cd14,Ier3,Piezo1,Tlr1,Dusp2,Mgat1,Trip10,Gna15,Sod2,Gdf15,Ccr1 |
| 6.423e-03 | -5.05 | CHIBA_RESPONSE_TO_TSA_UP | MSigDB lists | CHIBA_RESPONSE_TO_TSA_UP | 59 | 11 | 15632 | 1249 |
H2-Q4,Junb,H2-Q7,Fosb,Pdgfrb,Fos,H2-Q6,Trp53i11,Glrx,Vegfc,Mmp13 |
| 6.447e-03 | -5.04 | SWEET_KRAS_ONCOGENIC_SIGNATURE | MSigDB lists | SWEET_KRAS_ONCOGENIC_SIGNATURE | 84 | 14 | 15632 | 1249 |
Lcn2,Tank,Cited2,Dusp6,Pdk3,Vasp,Ccnd1,Phlda1,H2-Aa,Il18,Tgfbi,Hif1a,Cdkn1a,Glrx |
| 6.449e-03 | -5.04 | GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | MSigDB lists | GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | 448 | 51 | 15632 | 1249 |
Ednrb,Cav1,Sema3c,P2ry2,Nos2,Rictor,Rap1gap2,Sema4c,Tmod3,Adrb2,Sema4a,Whamm,Hcls1,Tmem123,Ezr,Sod2,Cyfip1,Dock4,Gclm,Edn1,Prkce,Ifrd1,Triobp,Nck1,Evl,Kat2b,Cx3cl1,Cdk5r1,Cdc42ep2,Gclc,Htr2a,Plek,Gja1,Gch1,Myadm,Csf3,Vasp,Hmox1,Adora2b,Ptgs2,Ptafr,Cdc42ep4,Spire1,Htr2b,Plod3,Swap70,Rab21,Hif1a,Icam1,Cd38,Hck |
| 6.486e-03 | -5.04 | regulation of mitotic nuclear division | biological process | GO:0007088 | 161 | 20 | 20694 | 1406 |
Hspa1a,Cenpe,Phip,Edn1,Atm,Sphk1,Igf1r,Trip13,Pdgfb,Nek6,Smc5,Tnf,Rgcc,Il1a,Pdgfrb,Hspa1b,Met,Chmp4b,Il1b,Pttg1 |
| 6.510e-03 | -5.03 | T-tubule | cellular component | GO:0030315 | 69 | 11 | 20747 | 1409 |
Prkce,Rtn2,Scn1b,Slc30a1,Ezr,Kcnj2,Cacna1d,Cacnb3,Atp2b4,Igf1r,Slc9a1 |
| 6.522e-03 | -5.03 | HAHTOLA_SEZARY_SYNDROM_DN | MSigDB lists | HAHTOLA_SEZARY_SYNDROM_DN | 36 | 8 | 15632 | 1249 |
Hopx,Irf8,Serpinb9,Ptch1,Ccl5,Il18rap,Ccl4,Dusp2 |
| 6.522e-03 | -5.03 | APPIERTO_RESPONSE_TO_FENRETINIDE_UP | MSigDB lists | APPIERTO_RESPONSE_TO_FENRETINIDE_UP | 36 | 8 | 15632 | 1249 |
Sdc4,Stxbp3,Ahsa1,Ccl2,Myadm,Brd2,Uchl1,Gdf15 |
| 6.522e-03 | -5.03 | REACTOME_GAB1_SIGNALOSOME | MSigDB lists | REACTOME_GAB1_SIGNALOSOME | 36 | 8 | 15632 | 1249 |
Src,Nr4a1,Trib3,Akt3,Cdkn1a,Mdm2,Phlpp1,Rictor |
| 6.522e-03 | -5.03 | GO_T_CELL_SELECTION | MSigDB lists | GO_T_CELL_SELECTION | 36 | 8 | 15632 | 1249 |
Fas,Spn,Syk,Cd74,Il15,Batf,Irf4,Il6 |
| 6.522e-03 | -5.03 | GO_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY | MSigDB lists | GO_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY | 36 | 8 | 15632 | 1249 |
Rasgrp1,Tap1,H2-Q4,H2-Q7,H2-Q6,Serpinb9,Pik3r6,Il12b |
| 6.522e-03 | -5.03 | HALLMARK_ANGIOGENESIS | MSigDB lists | HALLMARK_ANGIOGENESIS | 36 | 8 | 15632 | 1249 |
Ptk2,Itgav,Ccnd2,Timp1,Vcan,Jag1,Olr1,Pf4 |
| 6.522e-03 | -5.03 | REACTOME_PI3K_AKT_ACTIVATION | MSigDB lists | REACTOME_PI3K_AKT_ACTIVATION | 36 | 8 | 15632 | 1249 |
Cdkn1a,Rictor,Mdm2,Phlpp1,Akt3,Irs2,Trib3,Nr4a1 |
| 6.527e-03 | -5.03 | histone acetyltransferase binding | molecular function | GO:0035035 | 33 | 7 | 20217 | 1400 |
Cited2,Pla2g4a,Kat2b,Stat1,Egr1,Nr4a3,Hif1a |
| 6.530e-03 | -5.03 | positive regulation of lipid transport | biological process | GO:0032370 | 69 | 11 | 20694 | 1406 |
Fabp3,Acsl5,Il1b,Nr1h3,P2ry2,Il1a,Lipg,Nfkbia,Ptch1,Edn1,Sirt1 |
| 6.530e-03 | -5.03 | regulation of sprouting angiogenesis | biological process | GO:1903670 | 69 | 11 | 20694 | 1406 |
Ptgs2,Hmox1,Notch1,Akt3,Il10,Kdr,Itga5,Plk2,Thbs1,Klf2,Spred1 |
| 6.537e-03 | -5.03 | GO_ENDOSOMAL_PART | MSigDB lists | GO_ENDOSOMAL_PART | 396 | 46 | 15632 | 1249 |
Jak2,Ldlr,Rap2c,Pmepa1,Tlr9,Mmd,Lnpep,Cav1,Slc48a1,Fcgr1,Chmp4b,Atp11b,Pikfyve,Rab32,H2-Q4,Mitd1,Slc29a3,Irak2,Ikbke,H2-Ab1,Tlr3,Scyl2,Inpp5b,Rab10,Antxr1,H2-Aa,Snx2,Snx10,H2-Eb1,Myo1b,Fzd5,Irf7,Myd88,Cd14,Cd164,Clcn5,H2-Q7,Slc30a4,Pml,Tab2,Rab21,Slc39a4,Rffl,Ehd1,Plekhf2,H2-Q6 |
| 6.554e-03 | -5.03 | GDP-mannose metabolism | BIOCYC pathways | MOUSE_MANGDPMET-PWY | 9 | 4 | 1025 | 97 |
Hk3,Hk2,Gmppb,Hk1 |
| 6.579e-03 | -5.02 | Endosomal/Vacuolar pathway | REACTOME pathways | R-MMU-1236977 | 33 | 8 | 8608 | 757 |
H2-T24,H2-Q7,H2-Q6,Lnpep,H2-T22,H2-Q4,H2-T10,H2-M2 |
| 6.579e-03 | -5.02 | PH_domain | interpro domains | IPR001849 | 260 | 30 | 19984 | 1430 |
Psd4,Plekhg1,Dock10,Phlpp1,Swap70,Plcl2,Dgkh,Phldb1,Osbpl3,Adap2,Plekha2,Phlda1,Psd,Myo10,Grk3,Triobp,Plek,Spata13,Asap3,Akt3,Cyth3,Plekhn1,Arhgef3,Plekha4,Stap1,Arhgap26,Abr,Irs2,Plekha5,Plekhf2 |
| 6.588e-03 | -5.02 | - | gene3d domains | 1.10.150.60 | 15 | 5 | 8819 | 755 |
Arid5a,Jarid2,Arid5b,Arid4a,Kdm5b |
| 6.599e-03 | -5.02 | negative regulation of blood circulation | biological process | GO:1903523 | 42 | 8 | 20694 | 1406 |
Cx3cl1,Ahr,Dock4,Zc3h12a,Jak2,Dusp5,Hif1a,Pde5a |
| 6.599e-03 | -5.02 | regulation of cytokine production involved in inflammatory response | biological process | GO:1900015 | 42 | 8 | 20694 | 1406 |
Tlr6,Zc3h12a,Myd88,Tarm1,D1Ertd622e,Nod2,Nos2,Mefv |
| 6.599e-03 | -5.02 | blood vessel remodeling | biological process | GO:0001974 | 42 | 8 | 20694 | 1406 |
Ahr,Jag1,Axl,Acvrl1,Sema3c,Mdm2,Itga4,Lif |
| 6.622e-03 | -5.02 | GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | MSigDB lists | GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | 185 | 25 | 15632 | 1249 |
Aoah,Acvr1,Fut8,Upp1,Socs1,Abr,Itga4,Klf7,Batf,Slc16a1,Rrs1,Plod2,Psd4,Dusp6,Ikbkg,Ccl5,Slc39a14,Spint2,Cnn3,Trip13,Piezo1,Phyh,Acsl1,Pf4,Tax1bp1 |
| 6.622e-03 | -5.02 | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | 185 | 25 | 15632 | 1249 |
D16Ertd472e,Tbc1d1,Ctsc,Fut8,Rhoq,Cebpd,Rars,Gmppb,Rnf34,Zbp1,Lap3,Stx11,Hat1,Kpna3,Etnk1,Ifi35,Fndc3a,Rcn1,Kcna3,Tapbpl,Gfpt1,Sec24a,Clic4,Inpp1,Stip1 |
| 6.622e-03 | -5.02 | GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_DN | MSigDB lists | GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_DN | 185 | 25 | 15632 | 1249 |
Dmwd,Irf7,Map4k4,Jdp2,Mier3,Oas2,Oas1a,Trip13,Reps1,Frmd4a,Adora2b,Oas1g,Oasl1,Atp10a,Keap1,Cenpe,Spn,Nlrc5,Dync1h1,Ppp2r5a,Ifi44,Cdkn2d,Slfn5,Zbp1,Tspo |
| 6.622e-03 | -5.02 | GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_UP | MSigDB lists | GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_UP | 185 | 25 | 15632 | 1249 |
Dusp6,Jdp2,Tnfsf14,Plod2,Ralgds,Ppp2r1b,Rnf19b,Cxcl10,Acsl1,Phgdh,Pnp2,Tnfsf8,Aebp2,Dusp1,Ehd1,Plac8,Ass1,Arid5a,Eno1,Cd38,Ripk3,Clcn5,Tle3,Cd74,Cdk5r1 |
| 6.622e-03 | -5.02 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_UP | 185 | 25 | 15632 | 1249 |
Hsd17b7,Rbms1,Cxcl1,Pcdh7,Tlr2,Arid5b,Ier3,Casp2,Cxcl2,Eef1e1,G3bp2,Tlr1,Nos2,Hvcn1,Nlrp3,Egr1,Prdm1,Errfi1,Acvr1,Nfkbie,Cish,Slc15a3,Ccl2,Sod2,Tnf |
| 6.622e-03 | -5.02 | GSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | 185 | 25 | 15632 | 1249 |
Papss2,Hif1a,F10,Olr1,Hk3,Cst7,Srm,Aoah,Plac8,Eno1,Igsf6,Fcgr2b,Rab21,Hspa2,Cers6,Ift57,Fgl2,Sema4a,Glrx,Pgk1,Gng12,Antxr1,Alas1,Pstpip2,Cd69 |
| 6.628e-03 | -5.02 | Small_GTPase | interpro domains | IPR001806 | 133 | 18 | 19984 | 1430 |
Rab21,Rnd1,Rab10,Rab9,Rhou,Rab32,Rab19,Rap2c,Rac3,Nkiras1,Rhof,Gem,Rras2,Rhoc,Rhoq,Rnd3,Rhoh,Rab20 |
| 6.629e-03 | -5.02 | Dorso-ventral axis formation | KEGG pathways | mmu04320 | 26 | 7 | 7931 | 713 |
Notch2,Cpeb4,Ets2,Notch1,Spire1,Map2k1,Etv6 |
| 6.629e-03 | -5.02 | Dorso-ventral axis formation | KEGG pathways | ko04320 | 26 | 7 | 7931 | 713 |
Etv6,Spire1,Notch1,Map2k1,Ets2,Notch2,Cpeb4 |
| 6.652e-03 | -5.01 | GSE45365_CD8A_DC_VS_CD11B_DC_UP | MSigDB lists | GSE45365_CD8A_DC_VS_CD11B_DC_UP | 166 | 23 | 15632 | 1249 |
Upp1,Papss2,Pnpt1,Gng11,Bmp2,Tnfaip3,Dusp1,Txnrd1,Apobec3,Ddhd1,Tpst1,Gpsm2,Cycs,Ift57,Usp42,Fam111a,Fscn1,Pkp4,Ankib1,Ednrb,Psme2,Fzd1,Rhou |
| 6.666e-03 | -5.01 | apical junction complex | cellular component | GO:0043296 | 140 | 18 | 20747 | 1409 |
Ddx58,Rapgef2,Nectin2,Mtdh,Cyth3,Ccnd1,Usp53,Fzd5,Rpgrip1l,Micall2,Rap2c,Frmd6,Nectin4,Frmd4a,F11r,Vasp,Clmp,Mpp7 |
| 6.673e-03 | -5.01 | Choline metabolism in cancer | KEGG pathways | mmu05231 | 99 | 17 | 7931 | 713 |
Pla2g4a,Jun,Fos,Ralgds,Akt3,Plpp1,Pdgfb,Pdgfc,Slc44a1,Dgka,Map2k1,Pik3cd,Plpp3,Dgkh,Hif1a,Rac3,Pdgfrb |
| 6.673e-03 | -5.01 | Choline metabolism in cancer | KEGG pathways | ko05231 | 99 | 17 | 7931 | 713 |
Dgka,Pdgfc,Pdgfb,Plpp1,Slc44a1,Ralgds,Fos,Akt3,Pla2g4a,Jun,Rac3,Pdgfrb,Plpp3,Dgkh,Hif1a,Map2k1,Pik3cd |
| 6.683e-03 | -5.01 | NGUYEN_NOTCH1_TARGETS_UP | MSigDB lists | NGUYEN_NOTCH1_TARGETS_UP | 29 | 7 | 15632 | 1249 |
Psmd10,Tagln,Col18a1,Itgav,Stat5a,Nqo1,Hdac1 |
| 6.683e-03 | -5.01 | MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_DN | MSigDB lists | MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_DN | 29 | 7 | 15632 | 1249 |
Ccl12,Plscr1,Sdc4,H2-Eb1,Vrk2,Ccrl2,Pim1 |
| 6.683e-03 | -5.01 | GO_PROTEIN_SERINE_THREONINE_KINASE_INHIBITOR_ACTIVITY | MSigDB lists | GO_PROTEIN_SERINE_THREONINE_KINASE_INHIBITOR_ACTIVITY | 29 | 7 | 15632 | 1249 |
Prkar2b,Cdkn1a,Kat2b,Spred1,Cdkn2d,Spry2,Casp3 |
| 6.683e-03 | -5.01 | GO_NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND | MSigDB lists | GO_NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND | 29 | 7 | 15632 | 1249 |
Pf4,Il1b,Cx3cr1,Tnf,Il1a,Cx3cl1,Hspa1a |
| 6.683e-03 | -5.01 | GO_L_ALPHA_AMINO_ACID_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_L_ALPHA_AMINO_ACID_TRANSMEMBRANE_TRANSPORT | 29 | 7 | 15632 | 1249 |
Slc25a12,Slc7a5,Slc7a2,Slc25a22,Slc13a3,Slc7a8,Slc7a11 |
| 6.683e-03 | -5.01 | GO_RESPONSE_TO_ATP | MSigDB lists | GO_RESPONSE_TO_ATP | 29 | 7 | 15632 | 1249 |
Il1b,Casp1,Ccl12,P2ry12,Ptgs2,Sell,Sphk1 |
| 6.683e-03 | -5.01 | FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_DN | MSigDB lists | FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_DN | 29 | 7 | 15632 | 1249 |
Itga4,Cd274,Traf5,Hcls1,Slpi,Cd38,Ptges |
| 6.683e-03 | -5.01 | GO_MHC_PROTEIN_COMPLEX | MSigDB lists | GO_MHC_PROTEIN_COMPLEX | 29 | 7 | 15632 | 1249 |
H2-Aa,H2-Q7,H2-Ab1,H2-Eb1,H2-Q4,H2-Q6,Cd74 |
| 6.683e-03 | -5.01 | MODULE_367 | MSigDB lists | MODULE_367 | 29 | 7 | 15632 | 1249 |
Dgka,Htr2b,Gna15,Lpar1,P2ry2,Ccr1,Ednrb |
| 6.689e-03 | -5.01 | CDC5_01 | MSigDB lists | CDC5_01 | 224 | 29 | 15632 | 1249 |
H3f3b,Tnfsf10,Bambi,Rgs1,Rbms1,Gpr85,Frmd4a,Lyn,Uchl1,Cpeb4,Hivep3,Samsn1,Sesn3,Dusp14,Angpt1,Pbx1,Sgk3,Sdc1,Klf8,Nek6,Bcor,Hspa2,Errfi1,Egr2,Stat3,Sat1,Hmga1,Cited2,Bcl6 |
| 6.689e-03 | -5.01 | GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS | 224 | 29 | 15632 | 1249 |
Plagl1,Il1a,Phip,Cdk5r1,Plk3,Pml,Tnks1bp1,Crlf3,Pbx1,Ankrd17,Cnot4,Ccnd1,Mdm2,Edn1,Prkce,Prdm9,Tmod3,Smc5,Pkp4,Cdkn1a,Il1b,Plk2,Pdgfrb,Cenpj,Atm,Ube2e2,Casp2,Pdgfb,Btg2 |
| 6.690e-03 | -5.01 | GO_CHEMOKINE_BINDING | MSigDB lists | GO_CHEMOKINE_BINDING | 16 | 5 | 15632 | 1249 |
Cx3cr1,Itga4,Ccr1,Itgav,Zfp36 |
| 6.690e-03 | -5.01 | GO_REGULATION_OF_MITOCHONDRIAL_DEPOLARIZATION | MSigDB lists | GO_REGULATION_OF_MITOCHONDRIAL_DEPOLARIZATION | 16 | 5 | 15632 | 1249 |
Src,Gclm,Tspo,Gclc,Kdr |
| 6.690e-03 | -5.01 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 16 | 5 | 15632 | 1249 |
Met,Nr4a3,Hsph1,Hp,Txn1 |
| 6.690e-03 | -5.01 | GO_COPPER_ION_HOMEOSTASIS | MSigDB lists | GO_COPPER_ION_HOMEOSTASIS | 16 | 5 | 15632 | 1249 |
Sco1,Prnp,Slc31a2,Cutc,Slc31a1 |
| 6.690e-03 | -5.01 | MODULE_275 | MSigDB lists | MODULE_275 | 16 | 5 | 15632 | 1249 |
Itga9,Itgal,Itga5,Itgav,Tnc |
| 6.690e-03 | -5.01 | GO_REGULATION_OF_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY | 16 | 5 | 15632 | 1249 |
Wdfy1,Peli1,Tnfaip3,Lyn,Nr1h3 |
| 6.690e-03 | -5.01 | GO_MODULATION_OF_GROWTH_OF_SYMBIONT_INVOLVED_IN_INTERACTION_WITH_HOST | MSigDB lists | GO_MODULATION_OF_GROWTH_OF_SYMBIONT_INVOLVED_IN_INTERACTION_WITH_HOST | 16 | 5 | 15632 | 1249 |
Tnf,Sqstm1,Il10,Irf8,Il12b |
| 6.690e-03 | -5.01 | GO_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS | 16 | 5 | 15632 | 1249 |
Irs2,Lyn,Bcl6,Cd74,Il10 |
| 6.690e-03 | -5.01 | NIELSEN_LEIOMYOSARCOMA_UP | MSigDB lists | NIELSEN_LEIOMYOSARCOMA_UP | 16 | 5 | 15632 | 1249 |
Ccl5,H2-Ab1,Aim2,Vegfc,Slamf8 |
| 6.690e-03 | -5.01 | GO_TYPE_I_INTERFERON_RECEPTOR_BINDING | MSigDB lists | GO_TYPE_I_INTERFERON_RECEPTOR_BINDING | 16 | 5 | 15632 | 1249 |
Ifna6,Ifna1,Ifnb1,Ifna5,Ifna2 |
| 6.690e-03 | -5.01 | GO_TRANSFORMING_GROWTH_FACTOR_BETA_BINDING | MSigDB lists | GO_TRANSFORMING_GROWTH_FACTOR_BETA_BINDING | 16 | 5 | 15632 | 1249 |
Acvr1,Vasn,Acvrl1,Thbs1,Itgav |
| 6.690e-03 | -5.01 | BIOCARTA_RELA_PATHWAY | MSigDB lists | BIOCARTA_RELA_PATHWAY | 16 | 5 | 15632 | 1249 |
Tnfrsf1b,Nfkb1,Ikbkg,Nfkbia,Tnf |
| 6.690e-03 | -5.01 | GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT1_PROTEIN | MSigDB lists | GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT1_PROTEIN | 16 | 5 | 15632 | 1249 |
Il12b,Ptpn2,Socs1,Cd40,Lif |
| 6.690e-03 | -5.01 | TOMIDA_METASTASIS_DN | MSigDB lists | TOMIDA_METASTASIS_DN | 16 | 5 | 15632 | 1249 |
Sat1,Nr4a1,Eno2,Wars,Glrx |
| 6.690e-03 | -5.01 | GO_NEGATIVE_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL | MSigDB lists | GO_NEGATIVE_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL | 16 | 5 | 15632 | 1249 |
Trim13,Trim12c,Trim26,Trim21,Pml |
| 6.708e-03 | -5.00 | phosphoric diester hydrolase activity | molecular function | GO:0008081 | 87 | 13 | 20217 | 1400 |
Pde5a,Pde4b,Pde3b,Mppe1,Ccl5,Cnp,Pde7b,Pde1b,Prkar2b,Plcl2,Smpdl3b,Ccr1,Hmox1 |
| 6.729e-03 | -5.00 | BRIGHT | smart domains | SM00501 | 15 | 5 | 9567 | 823 |
Arid5a,Kdm5b,Jarid2,Arid5b,Arid4a |
| 6.735e-03 | -5.00 | Cross-presentation of soluble exogenous antigens (endosomes) | REACTOME pathways | R-MMU-1236978 | 47 | 10 | 8608 | 757 |
Psmb6,Psme2,Psma6,Psmd10,Psme1,Psme2b,Fcgr1,Psmb8,Psmb9,Psmb10 |
| 6.735e-03 | -5.00 | VEGFA-VEGFR2 Pathway | REACTOME pathways | R-MMU-4420097 | 287 | 38 | 8608 | 757 |
Jak2,Map2k1,Itgav,Axl,Ppp2r1b,Kdr,Pdgfrb,Ksr1,Il2rg,Src,Ppp2r5a,Irs2,Rictor,Angpt1,Psme2b,Pdgfb,Spred1,Kitl,Psmb6,Dusp6,Psme1,Sphk1,Dusp5,Rasgrp1,Cyfip1,Psmb9,Rapgef2,Mapkapk2,Psme2,Psma6,Trib3,Psmd10,Cav1,Ptk2,Met,Psmb8,Psmb10,Nck1 |
| 6.752e-03 | -5.00 | OCT1_Q6 | MSigDB lists | OCT1_Q6 | 234 | 30 | 15632 | 1249 |
Gadd45g,Mid1,Egr2,Mtus1,Tcf4,Parp8,Slc7a11,Flrt3,Rgs3,Pdgfc,Tle3,Slc39a13,Prdm1,Lif,Csf3,Hivep3,Stat4,Adora2a,Ppp2r3a,Nrp2,Col11a2,Rel,Dusp6,H3f3b,Zhx2,Lyn,Pik3cd,Gpr85,Kpna3,Pim2 |
| 6.753e-03 | -5.00 | positive regulation of prostaglandin secretion | biological process | GO:0032308 | 12 | 4 | 20694 | 1406 |
Il1b,Edn1,P2ry2,Il1a |
| 6.753e-03 | -5.00 | positive regulation of ATP biosynthetic process | biological process | GO:2001171 | 12 | 4 | 20694 | 1406 |
Pid1,Myc,Map2k1,Stat3 |
| 6.753e-03 | -5.00 | negative regulation of mast cell activation | biological process | GO:0033004 | 12 | 4 | 20694 | 1406 |
Milr1,Cd300lf,Hmox1,Rabgef1 |
| 6.753e-03 | -5.00 | T cell cytokine production | biological process | GO:0002369 | 12 | 4 | 20694 | 1406 |
Dennd1b,Il12b,Il18,Il18rap |
| 6.753e-03 | -5.00 | regulation of hypersensitivity | biological process | GO:0002883 | 12 | 4 | 20694 | 1406 |
Fcgr1,Spn,C3,Fcgr2b |
| 6.753e-03 | -5.00 | oligopeptide transport | biological process | GO:0006857 | 12 | 4 | 20694 | 1406 |
Slco3a1,Slc15a3,Slc7a11,Abcc1 |
| 6.753e-03 | -5.00 | negative regulation of transcription from RNA polymerase II promoter in response to stress | biological process | GO:0097201 | 12 | 4 | 20694 | 1406 |
Cited2,Nck1,Jun,Ppp1r15a |
| 6.753e-03 | -5.00 | regulation of skeletal muscle satellite cell proliferation | biological process | GO:0014842 | 12 | 4 | 20694 | 1406 |
Cflar,Jak2,Stat3,Angpt1 |
| 6.753e-03 | -5.00 | 4-hydroxyproline metabolic process | biological process | GO:0019471 | 12 | 4 | 20694 | 1406 |
P4ha1,Ero1l,P4ha2,Egln3 |
| 6.753e-03 | -5.00 | negative regulation by host of viral transcription | biological process | GO:0043922 | 12 | 4 | 20694 | 1406 |
Hdac1,Jun,Ccl4,Ccl5 |
| 6.753e-03 | -5.00 | positive regulation of interleukin-2 biosynthetic process | biological process | GO:0045086 | 12 | 4 | 20694 | 1406 |
Stat5a,Il1a,Irf4,Il1b |
| 6.753e-03 | -5.00 | regulation of Fc receptor mediated stimulatory signaling pathway | biological process | GO:0060368 | 12 | 4 | 20694 | 1406 |
Lyn,Ptprj,Rabgef1,Plscr1 |
| 6.753e-03 | -5.00 | regulation of unsaturated fatty acid biosynthetic process | biological process | GO:2001279 | 12 | 4 | 20694 | 1406 |
Il1b,Ptgs2,Pla2g4a,Sirt1 |
| 6.753e-03 | -5.00 | intracellular signal transduction involved in G1 DNA damage checkpoint | biological process | GO:1902400 | 12 | 4 | 20694 | 1406 |
Cdkn1a,Mdm2,Pml,Casp2 |
| 6.753e-03 | -5.00 | signal transduction involved in mitotic G1 DNA damage checkpoint | biological process | GO:0072431 | 12 | 4 | 20694 | 1406 |
Mdm2,Cdkn1a,Pml,Casp2 |
| 6.753e-03 | -5.00 | regulation of hydrogen peroxide-mediated programmed cell death | biological process | GO:1901298 | 12 | 4 | 20694 | 1406 |
Hsph1,Hk3,Glrx,Met |
| 6.759e-03 | -5.00 | MODULE_532 | MSigDB lists | MODULE_532 | 345 | 41 | 15632 | 1249 |
Tuba4a,Gja1,Plekhg1,Lap3,Gem,Csf1,Timeless,Ppp4r2,Larp1,Mmp9,Ptgs2,Acsl1,Cxcl10,Clcf1,Chd9,Nfil3,Morc3,Hivep2,Ccl12,Plekhf2,Arid5a,Fos,Cited2,Stat3,Mmp14,Kdm5b,Acvr1,Gpr68,Prdm1,Ddx60,Kat2b,Il1a,Fpr2,Phip,Zbtb5,Sav1,Mapkbp1,Smg7,Slamf7,Ncoa7,Mcmbp |
| 6.759e-03 | -5.00 | KOYAMA_SEMA3B_TARGETS_DN | MSigDB lists | KOYAMA_SEMA3B_TARGETS_DN | 345 | 41 | 15632 | 1249 |
Hlx,Pgs1,Nlrp3,Traf1,Gpc1,Traf5,Tap1,Myo10,Foxp4,Plekhf2,Klf6,Hivep2,Nfkbia,Cd40,Tcf4,Hspa1a,Psmb9,Nqo1,Gng4,Hmgcs1,Larp1,Arid5b,Adora2b,Kitl,Rsbn1,Prkar2b,Pmepa1,Frmd6,Slc37a3,Lhx2,Birc3,Lmo4,Cep350,Cav1,Sema3c,Icosl,Stx11,AA467197,Adora2a,Sh3bp4,Jag1 |
| 6.782e-03 | -4.99 | negative regulation of G1/S transition of mitotic cell cycle | biological process | GO:2000134 | 60 | 10 | 20694 | 1406 |
Pml,Casp2,Cdkn1a,Slfn1,Plk3,Ccl12,Ccnd1,Rbl1,Dcun1d3,Mdm2 |
| 6.784e-03 | -4.99 | cellular response to extracellular stimulus | biological process | GO:0031668 | 217 | 25 | 20694 | 1406 |
Ldha,Asns,Nmral1,Cpeb4,Atf3,Adora2b,Cdkn1a,Higd1a,Eif2ak2,Wdr59,Sesn3,Fos,Jun,P2ry12,Mmp9,Sirt1,Slc2a1,Gsdmd,Zc3h12a,Itga4,Axl,Vcam1,Slc39a4,Fas,Pim1 |
| 6.788e-03 | -4.99 | CAIRO_HEPATOBLASTOMA_CLASSES_DN | MSigDB lists | CAIRO_HEPATOBLASTOMA_CLASSES_DN | 195 | 26 | 15632 | 1249 |
C1ra,Bcl6,Nfkbia,Hivep2,Cx3cr1,Dnase1l3,Sgcb,Fabp3,Slc30a1,Egr1,Col18a1,Fas,Uba7,Alas1,Htra1,St3gal5,Psme2,Phlda1,Zeb1,Casp4,Mfap3l,4930523C07Rik,Acsl5,Rcan1,Phyh,Atp10a |
| 6.814e-03 | -4.99 | SCHUHMACHER_MYC_TARGETS_UP | MSigDB lists | SCHUHMACHER_MYC_TARGETS_UP | 76 | 13 | 15632 | 1249 |
Rrs1,Srm,Nampt,Slc39a14,Myc,Cycs,Ctsc,Acsl1,Odc1,Ak4,Ldha,Lrp8,Slc16a1 |
| 6.814e-03 | -4.99 | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | MSigDB lists | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | 76 | 13 | 15632 | 1249 |
Map4k4,Ezr,Axl,Gem,Casp4,Sh3bp4,Stat1,Pik3cd,Trib1,Thbs1,Cflar,Trp53i11,Dusp14 |
| 6.828e-03 | -4.99 | EN1_01 | MSigDB lists | EN1_01 | 102 | 16 | 15632 | 1249 |
Rapgef5,Map4k4,Tcf4,Sipa1l1,Sat1,Caml,Mmp14,Eya4,Cd55,Bcor,Fndc3a,Nxf1,Nr4a3,Sav1,Sh3bgrl2,Notch1 |
| 6.848e-03 | -4.98 | STEIN_ESRRA_TARGETS_UP | MSigDB lists | STEIN_ESRRA_TARGETS_UP | 335 | 40 | 15632 | 1249 |
Higd1a,Asns,Rnaset2a,4930523C07Rik,Rnf14,Hk1,Gdf15,Slc25a12,Egln3,Rap1gap2,Trim14,Pdss1,St3gal5,Ampd3,Slc2a6,Alas1,Scn1b,Slc31a1,Mmp9,Fam162a,Rnaset2b,Fscn1,Cflar,Inpp1,Ust,Rhof,Ets2,Dusp1,Sod2,Slc16a3,Ctsc,Cycs,Rab21,Rhoq,Ciapin1,Jmjd6,Rnf139,Aff1,Rnf34,Slc16a1 |
| 6.871e-03 | -4.98 | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_UP | MSigDB lists | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_UP | 157 | 22 | 15632 | 1249 |
Ppfibp1,Angpt1,Lpcat2,Pbx1,Sav1,Gbp3,C3,Nfkbiz,Rsad2,Rbpms,Rin2,Atxn7l1,Caml,Ksr1,Bcorl1,Abcb1a,C1rl,Plod2,Lrp4,Sesn3,Igsf9,Birc3 |
| 6.871e-03 | -4.98 | GO_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | MSigDB lists | GO_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | 157 | 22 | 15632 | 1249 |
Mmp9,Zc3h12a,Evl,Ptk2,Sema4a,Ptgs2,Hif1a,Kdr,Thbs1,Angpt1,Vegfc,Notch1,Stat5a,Src,Jun,Prkce,Nrp2,Edn1,Pdgfb,Acvrl1,Met,Glipr2 |
| 6.871e-03 | -4.98 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_UP | 157 | 22 | 15632 | 1249 |
Il4ra,Ccl22,Etv3,Bcl2a1d,I830077J02Rik,Mid1,Ctsc,Pla2g4a,Timp1,Gpr18,Bcl2a1b,Bcl2l11,Aoah,Nfil3,Bcl2a1a,St3gal1,Pde7b,Spint2,Rap1gap2,Rrs1,Dusp6,Dach1 |
| 6.889e-03 | -4.98 | GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_UP | 176 | 24 | 15632 | 1249 |
Dtnb,Casp2,Ift57,Slc44a1,Procr,Ptch1,Acpp,Zc3h12c,Rnaset2a,Srm,Crbn,Pde4b,Ehd1,Fam162a,Rnaset2b,Tnfaip2,Extl2,Clec5a,Fpr2,Acvr1b,Calcrl,Uchl1,Mmp9,Hmgcs1 |
| 6.889e-03 | -4.98 | GSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_UP | MSigDB lists | GSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_UP | 176 | 24 | 15632 | 1249 |
Gng4,Cd200,Hmox1,H2-Ab1,Smox,Nfkb2,Ccl5,Tnfrsf1b,Txn1,Pdk3,Rel,Fabp7,Slc39a14,Cd14,Sdc4,Batf,Rbms2,Prdx1,Me1,Usp53,Txnrd1,Cebpd,Kdm5b,Ogfrl1 |
| 6.889e-03 | -4.98 | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_UP | MSigDB lists | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_UP | 176 | 24 | 15632 | 1249 |
Jdp2,Txn1,Slc13a3,Eno2,Pdgfb,Egln3,Maff,Ldha,Adrb2,Acsl1,Ptgs2,Asf1a,Rap2c,Pgk1,Fam162a,Rab32,Nfkbia,Rbbp8,Casp3,Ift57,Ogfrl1,Marcksl1,Hlx,Agtrap |
| 6.889e-03 | -4.98 | GSE37532_WT_VS_PPARG_KO_LN_TCONV_UP | MSigDB lists | GSE37532_WT_VS_PPARG_KO_LN_TCONV_UP | 176 | 24 | 15632 | 1249 |
Acvr1b,Atp10a,Dyrk2,Frmd6,Slfn9,Lad1,4930523C07Rik,Sesn3,Tlr1,Dcp2,Cyth3,Kat2b,Hhex,Itga4,Ncoa7,Gpr18,Bcl2l11,Lztfl1,Dock10,Nr3c1,Slfn8,Dennd1b,Gbp4,Gbp9 |
| 6.893e-03 | -4.98 | platelet aggregation | biological process | GO:0070527 | 26 | 6 | 20694 | 1406 |
Plek,Stxbp3,Stxbp1,Ubash3b,Slc7a11,P2ry12 |
| 6.893e-03 | -4.98 | negative regulation of ATP metabolic process | biological process | GO:1903579 | 26 | 6 | 20694 | 1406 |
Ddit4,Ier3,Nupr1,Stat3,Tspo,Pid1 |
| 6.893e-03 | -4.98 | regulation of urine volume | biological process | GO:0035809 | 26 | 6 | 20694 | 1406 |
Ptger4,Adrb2,Edn1,Ednrb,Mllt6,Adora2a |
| 6.893e-03 | -4.98 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0045736 | 26 | 6 | 20694 | 1406 |
Hhex,Tnfaip3,Cdkn1a,Kat2b,Cdkn2d,Casp3 |
| 6.893e-03 | -4.98 | negative regulation of glucose transmembrane transport | biological process | GO:0010829 | 26 | 6 | 20694 | 1406 |
Pid1,Tnf,Il1b,Myc,Stxbp3,Rhoq |
| 6.910e-03 | -4.97 | sarcolemma | cellular component | GO:0042383 | 162 | 20 | 20747 | 1409 |
Slc2a1,Dst,Ptk2,Prkce,Rtn2,Slc30a1,Scn1b,Agrn,Ezr,Fas,Kcnj2,Adrb2,Vcam1,Cav1,Atp2b4,Cacnb3,Cacna1d,Slc9a1,Sgcb,Igf1r |
| 6.922e-03 | -4.97 | amide binding | molecular function | GO:0033218 | 362 | 38 | 20217 | 1400 |
Tlr2,Tlr1,Fzd5,Tap2,Ednrb,Pcx,Marco,H2-M2,Gsap,Prnp,Ldlr,Apba1,Inhba,Cd300lf,H2-T10,H2-Aa,Msr1,H2-T22,Calcrl,Fpr2,Cd74,Lnpep,Lrp8,Cd14,H2-Q6,Igf1r,Fcgr2b,Nfkbia,Ptges,Gsr,H2-Ab1,H2-T24,Tap1,H2-Q7,H2-Q4,Adrb2,Nod2,Tlr6 |
| 6.923e-03 | -4.97 | GGCAGCT_MIR22 | MSigDB lists | GGCAGCT_MIR22 | 205 | 27 | 15632 | 1249 |
Tlk2,Mecp2,Nr3c1,Tet2,Slc2a1,Tagln,Plagl2,Prpf38a,Ccdc88b,Cyth3,Mxd1,Sirt1,Akt3,Slc9a1,Bcl9,Ppp1r15b,H3f3b,Cdkn1a,Rsbn1,Clic4,Chd9,Cldnd1,Pik3cd,Mthfd2,Fam53c,Max,Il13ra1 |
| 6.961e-03 | -4.97 | regeneration | biological process | GO:0031099 | 99 | 14 | 20694 | 1406 |
Cdkn1a,Plau,Jun,Bcl9,Cflar,Ccnd1,Hmox1,Fas,Ifrd1,Lif,Jak2,Gja1,Itpr1,Tnc |
| 6.961e-03 | -4.97 | positive regulation of blood circulation | biological process | GO:1903524 | 89 | 13 | 20694 | 1406 |
Gch1,Htr2a,Adrb2,Pde5a,Cd38,Sirt1,Cav1,Icam1,Ptgs2,Pdgfb,Ptafr,Edn1,Gja1 |
| 6.961e-03 | -4.97 | stem cell development | biological process | GO:0048864 | 89 | 13 | 20694 | 1406 |
Kitl,Jag1,Cited2,Phactr4,Htr2b,Edn1,Hif1a,Sema4c,Sema4a,Acvr1,Sema3c,Nrp2,Ednrb |
| 6.983e-03 | -4.96 | tube formation | biological process | GO:0035148 | 173 | 21 | 20694 | 1406 |
Sdc4,Notch1,Casp8,Bcl2l11,Mthfd1l,Ift57,Apaf1,Lhx2,Sec24b,Fzd1,Vasp,Hif1a,Sema4c,Spint2,Mthfr,Lmo4,Ptch1,Casp3,Cited2,Phactr4,Tulp3 |
| 6.991e-03 | -4.96 | temperature homeostasis | biological process | GO:0001659 | 34 | 7 | 20694 | 1406 |
Il1a,Egr1,Il1rn,Il1b,Stat3,Htr2a,Adrb2 |
| 6.991e-03 | -4.96 | response to bronchodilator | biological process | GO:0097366 | 34 | 7 | 20694 | 1406 |
Adora2a,Itgav,Traf2,Cflar,Pde1b,Hdac1,Thbs1 |
| 6.991e-03 | -4.96 | respiratory gaseous exchange by respiratory system | biological process | GO:0007585 | 34 | 7 | 20694 | 1406 |
Edn1,Adrb2,Fut8,Mecp2,Stk40,Chst11,Dach1 |
| 6.991e-03 | -4.96 | regulation of superoxide metabolic process | biological process | GO:0090322 | 34 | 7 | 20694 | 1406 |
Tnf,Gch1,Cxcl1,Fpr2,Acp5,Il18,Syk |
| 6.991e-03 | -4.96 | positive regulation of collagen metabolic process | biological process | GO:0010714 | 34 | 7 | 20694 | 1406 |
Serpine1,Pdgfb,Prdx5,Pdgfrb,Ccl2,Il18,Rgcc |
| 7.030e-03 | -4.96 | GCM_Q2 | MSigDB lists | GCM_Q2 | 215 | 28 | 15632 | 1249 |
Cx3cl1,Tpi1,Prdm1,Plagl2,Foxp4,Ets2,Ankrd17,Chst11,Vcan,Psd,Fchsd2,Slc44a1,Dusp5,Ell2,Mmp9,Ptprj,Zhx2,H3f3b,Igf1r,Rbms1,Daam1,Dcun1d3,Sesn3,Nfkbid,Piezo1,Ext1,Pdgfb,Reps1 |
| 7.030e-03 | -4.96 | CEBPDELTA_Q6 | MSigDB lists | CEBPDELTA_Q6 | 215 | 28 | 15632 | 1249 |
Wars,Ube2e2,Fosb,Ptch1,Osm,Il1rn,Itga5,Scyl2,Ptgir,Gpr85,Trib1,Pde1b,Slc44a1,Pla2g4a,Mid1,Slc7a11,Nr4a1,Jun,Cited2,Fos,Tal2,Lipg,Tnks1bp1,Rab3ip,Notch1,Atf3,Nr1h3,Ccnd2 |
| 7.045e-03 | -4.96 | GO_CELLULAR_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_HOMEOSTASIS | 632 | 68 | 15632 | 1249 |
Gja1,Ccl5,Ccr1,Slc4a7,Txn1,Slc31a2,Atp6v1d,Hk2,Hmox1,Slc31a1,Cd55,Ptger4,Grina,Clic4,Htr2b,Glrx,Il1b,Txnrd1,Cd40,Itpr1,Swap70,Cp,Slc39a4,Gsr,Atp13a1,Pml,Slc39a13,Hif1a,Icam1,Sgk3,Cd38,Hk1,Ednrb,S100a8,Pdk3,Lcn2,P2ry2,Nos2,Gna15,Cav1,Sco1,Slc9a1,Sirt1,Slc39a14,Nox1,Mafg,Rab20,Lpar1,Cacnb3,Jak2,Xcr1,Ccl12,Ccl2,Myc,Il6,Prkce,Ccr3,Kcnj2,Edn1,Fas,Slc30a1,Irs2,Prnp,Gclc,Htr2a,Plau,Hk3,Atp2b4 |
| 7.070e-03 | -4.95 | PH | pfam domains | PF00169 | 174 | 22 | 18711 | 1348 |
Dock10,Plekha4,Triobp,Myo10,Phlpp1,Plek,Akt3,Dgkh,Spata13,Cyth3,Plekha2,Swap70,Stap1,Arhgap26,Plekha5,Irs2,Grk3,Adap2,Asap3,Abr,Phldb1,Plekhf2 |
| 7.080e-03 | -4.95 | Ras | pfam domains | PF00071 | 133 | 18 | 18711 | 1348 |
Rhoh,Nkiras1,Rab21,Rhoc,Rab10,Rnd1,Rab9,Gem,Rhoq,Rab32,Rac3,Rap2c,Rab20,Rnd3,Rhou,Rras2,Rhof,Rab19 |
| 7.087e-03 | -4.95 | HALLMARK_HEME_METABOLISM | MSigDB lists | HALLMARK_HEME_METABOLISM | 186 | 25 | 15632 | 1249 |
Gclc,Kat2b,Slc30a1,Minpp1,Gclm,Nr3c1,Optn,Pcx,P4ha2,Klf3,Slc25a37,Slc7a11,Gypc,Slc2a1,Rcl1,Agpat4,Tcea1,Endod1,Smox,Ell2,C3,Btg2,Rnf19a,Asns,Daam1 |
| 7.087e-03 | -4.95 | GSE34515_CD16_POS_MONOCYTE_VS_DC_UP | MSigDB lists | GSE34515_CD16_POS_MONOCYTE_VS_DC_UP | 186 | 25 | 15632 | 1249 |
Chic2,Ebi3,Kpna3,Rcl1,Frmd6,Tnip1,Mcm9,Itgal,Jarid2,Junb,Hivep3,Plscr1,Flnb,Hif1a,Cdk5r1,Stau1,Il15,Arid5a,Serp1,Klf6,Nfkbia,Rin2,Fgl2,Zfp800,Acvrl1 |
| 7.087e-03 | -4.95 | GSE18893_CTRL_VS_TNF_TREATED_TCONV_2H_UP | MSigDB lists | GSE18893_CTRL_VS_TNF_TREATED_TCONV_2H_UP | 186 | 25 | 15632 | 1249 |
Rars,Rhoh,Gys1,Irak3,Morc3,Slc16a3,Psmb9,Psmd10,Katna1,Samd9l,Triobp,Acvrl1,Xkr8,Map2k4,Plcl2,Rap2c,Psmb8,Jdp2,Cd86,Cenpj,Dmwd,St3gal5,G3bp2,AA467197,Syne2 |
| 7.087e-03 | -4.95 | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_MAC_UP | 186 | 25 | 15632 | 1249 |
Hmox1,Trib1,Pim1,Kcna3,Nr4a3,Il1rn,Tax1bp1,Htr2b,Brd2,Asns,Tnfsf14,Trip13,Usp12,Abr,Nupr1,Ccl22,Aldh1b1,Fgr,Traf5,Txnrd1,Ccl12,Tmem184b,Irf4,Ppp2r5a,Pcx |
| 7.087e-03 | -4.95 | GSE24814_STAT5_KO_VS_WT_PRE_BCELL_DN | MSigDB lists | GSE24814_STAT5_KO_VS_WT_PRE_BCELL_DN | 186 | 25 | 15632 | 1249 |
Pde3b,Herc3,Il1a,Katna1,Gclm,Bcl2a1d,Cst7,Bcl2a1b,Aoah,Klf6,Itpr1,Gpr18,Sec24a,Bcl2a1a,Dck,Ak4,Zfp36,Sap30,Ext1,Spint2,Slc39a14,Psd4,Clic5,Jarid2,Gna15 |
| 7.111e-03 | -4.95 | GO_NEGATIVE_REGULATION_OF_T_CELL_PROLIFERATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_T_CELL_PROLIFERATION | 44 | 9 | 15632 | 1249 |
Casp3,Peli1,Tnfrsf14,Pde5a,H2-Eb1,Spn,Il10,Cd274,Prnp |
| 7.117e-03 | -4.95 | NATSUME_RESPONSE_TO_INTERFERON_BETA_UP | MSigDB lists | NATSUME_RESPONSE_TO_INTERFERON_BETA_UP | 68 | 12 | 15632 | 1249 |
Nfkb1,Eif2ak2,Dnaja1,Tnfsf14,Vcam1,Il15ra,Apaf1,Stat1,Fas,Casp7,Il18,Irf1 |
| 7.117e-03 | -4.95 | YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN | MSigDB lists | YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN | 68 | 12 | 15632 | 1249 |
Socs3,Malt1,Cpeb4,Hsph1,Icam1,Cacybp,Phyh,Ahsa1,Tnc,Tor1aip2,Ptges,Samd9l |
| 7.117e-03 | -4.95 | PID_TELOMERASE_PATHWAY | MSigDB lists | PID_TELOMERASE_PATHWAY | 68 | 12 | 15632 | 1249 |
Nfkb1,Mxd1,Max,Atm,Jun,Fos,Irf1,Znfx1,Myc,Sap30,Hdac1,Ccnd1 |
| 7.117e-03 | -4.95 | chr1p22 | MSigDB lists | chr1p22 | 68 | 12 | 15632 | 1249 |
Lrrc8c,Gbp2,Gfi1,Gbp2b,Dr1,Gbp3,Mcoln2,Gbp9,Gbp4,Cnn3,Lmo4,Gbp7 |
| 7.117e-03 | -4.95 | KEGG_PANCREATIC_CANCER | MSigDB lists | KEGG_PANCREATIC_CANCER | 68 | 12 | 15632 | 1249 |
Rac3,Pik3r5,Ikbkg,Stat1,Nfkb1,Map2k1,Pik3cd,Stat3,Akt3,Ralgds,Ccnd1,Vegfc |
| 7.144e-03 | -4.94 | mannitol degradation II | BIOCYC pathways | MOUSE_PWY-3861 | 5 | 3 | 1025 | 97 |
Hk2,Hk1,Hk3 |
| 7.180e-03 | -4.94 | regulation of cell growth | biological process | GO:0001558 | 430 | 43 | 20694 | 1406 |
Sphk1,Dbnl,Ifrd1,Crkl,Edn1,Gja1,Sema4c,Crlf3,Inhba,Osgin2,Cdkn2d,Dnajb2,Psmd10,Cdk5r1,Tomm70a,Bcl6,Sirt1,Trip10,Pttg1,Mmp14,Ptk2,Mndal,Cyfip1,Mecp2,Sh3bp4,Dcun1d3,Acvr1b,Mul1,Sema3c,Cd38,Slc9a1,Dcbld2,Nr3c1,Acvrl1,Gng4,Cdkn1a,Sema4a,Rab21,Pml,Eif4g2,Ptprj,Sertad3,4932438A13Rik |
| 7.183e-03 | -4.94 | respiratory tube development | biological process | GO:0030323 | 218 | 25 | 20694 | 1406 |
Stk40,Lox,Hopx,Pdpn,Lif,Tulp3,Tnc,Kdr,Map2k1,Timeless,Slc7a11,Jmjd6,Spry2,Klf2,Errfi1,Foxp4,Mmp14,Gpsm2,Hmga2,Hhex,Notch1,Sav1,Plod3,Sec24b,Pdgfrb |
| 7.224e-03 | -4.93 | cyclin-dependent protein serine/threonine kinase inhibitor activity | molecular function | GO:0004861 | 12 | 4 | 20217 | 1400 |
Kat2b,Casp3,Cdkn1a,Cdkn2d |
| 7.224e-03 | -4.93 | glucose binding | molecular function | GO:0005536 | 12 | 4 | 20217 | 1400 |
Hk3,Hk1,Hk2,Gys1 |
| 7.224e-03 | -4.93 | profilin binding | molecular function | GO:0005522 | 12 | 4 | 20217 | 1400 |
Cyfip1,Evl,Vasp,Rhoq |
| 7.224e-03 | -4.93 | 3',5'-cyclic-AMP phosphodiesterase activity | molecular function | GO:0004115 | 12 | 4 | 20217 | 1400 |
Pde3b,Pde1b,Pde7b,Pde4b |
| 7.246e-03 | -4.93 | GSE2706_LPS_VS_R848_AND_LPS_2H_STIM_DC_UP | MSigDB lists | GSE2706_LPS_VS_R848_AND_LPS_2H_STIM_DC_UP | 139 | 20 | 15632 | 1249 |
Ppfibp2,Dusp16,Pde3b,Tmem67,Il2rg,Aldh1b1,Slc39a13,Ell2,Pcgf5,Ch25h,Jag1,Gpr35,Nfkbib,Wdr59,P2ry2,Igsf8,Trip10,Psmb9,Ppp1r14b,Plek |
| 7.262e-03 | -4.93 | P-body | cellular component | GO:0000932 | 70 | 11 | 20747 | 1409 |
Dcp1a,Dcp2,Noct,Sqstm1,Polr2g,Mov10,Trim12c,Xrn1,Zfp36,Zc3h12a,Psma6 |
| 7.266e-03 | -4.92 | Integrin_alpha-2 | interpro domains | IPR013649 | 18 | 5 | 19984 | 1430 |
Itga5,Itga4,Itgav,Itgal,Itga9 |
| 7.266e-03 | -4.92 | Integrin_alpha | interpro domains | IPR000413 | 18 | 5 | 19984 | 1430 |
Itgal,Itga9,Itgav,Itga5,Itga4 |
| 7.266e-03 | -4.92 | FG-GAP | interpro domains | IPR013517 | 18 | 5 | 19984 | 1430 |
Itgal,Itga9,Itgav,Itga4,Itga5 |
| 7.270e-03 | -4.92 | Cd40 (CD40 antigen) | protein interactions | 21939 | 19 | 6 | 7778 | 753 |
Birc2,Birc3,Traf2,Ikbkg,Traf5,Map2k4 |
| 7.284e-03 | -4.92 | inositol lipid-mediated signaling | biological process | GO:0048017 | 70 | 11 | 20694 | 1406 |
Ptafr,Pdgfrb,Htr2b,Edn1,Igf1r,Htr2a,Pik3r5,Pik3cd,Pik3r6,Ezr,Adap2 |
| 7.292e-03 | -4.92 | PROTEIN_KINASE_TYR | prosite domains | PS00109 | 96 | 15 | 13278 | 1037 |
Flt1,Ptk2,Prag1,Hck,Jak2,Src,Tyk2,Lyn,Met,Kdr,Igf1r,Fgr,Syk,Axl,Pdgfrb |
| 7.311e-03 | -4.92 | TTGCWCAAY_CEBPB_02 | MSigDB lists | TTGCWCAAY_CEBPB_02 | 60 | 11 | 15632 | 1249 |
Trib1,Angpt1,Slc7a11,Serpine1,Sik3,Nrp2,Kcnj2,Etv6,Gsr,Nfkbie,Vcan |
| 7.311e-03 | -4.92 | LIN_NPAS4_TARGETS_DN | MSigDB lists | LIN_NPAS4_TARGETS_DN | 60 | 11 | 15632 | 1249 |
Egr2,Arl5b,Gadd45g,Dusp4,Errfi1,Egr1,Ier2,Egr3,Slc4a7,Osgin2,Etv3 |
| 7.311e-03 | -4.92 | AKL_HTLV1_INFECTION_DN | MSigDB lists | AKL_HTLV1_INFECTION_DN | 60 | 11 | 15632 | 1249 |
Dusp4,Stap1,Dennd1b,Serp1,Jun,Ptpn2,Cd86,Hopx,Dusp6,Mdfic,Ptgs2 |
| 7.320e-03 | -4.92 | - | gene3d domains | 3.40.50.12190 | 2 | 2 | 8819 | 755 |
Tor1aip1,Tor1aip2 |
| 7.320e-03 | -4.92 | - | gene3d domains | 3.10.260.40 | 2 | 2 | 8819 | 755 |
Bcor,Bcorl1 |
| 7.337e-03 | -4.91 | REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 | MSigDB lists | REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 | 52 | 10 | 15632 | 1249 |
Cdkn1a,Psma6,Psme2,Psmd10,Psmb9,Psmb10,Psme1,Psmb8,Ccne1,Psmb6 |
| 7.341e-03 | -4.91 | embryonic epithelial tube formation | biological process | GO:0001838 | 152 | 19 | 20694 | 1406 |
Vasp,Fzd1,Cited2,Phactr4,Tulp3,Ptch1,Mthfr,Lmo4,Casp3,Hif1a,Spint2,Sema4c,Casp8,Sdc4,Sec24b,Lhx2,Apaf1,Ift57,Mthfd1l |
| 7.356e-03 | -4.91 | - | gene3d domains | 2.60.40.340 | 10 | 4 | 8819 | 755 |
Rel,Nfkb2,Nfkb1,Relb |
| 7.379e-03 | -4.91 | Rel (reticuloendotheliosis oncogene) | protein interactions | 19696 | 9 | 4 | 7778 | 753 |
Bcl2a1a,Rel,Nos2,Il12b |
| 7.383e-03 | -4.91 | p75NTR signals via NF-kB | REACTOME pathways | R-MMU-193639 | 15 | 5 | 8608 | 757 |
Ripk2,Myd88,Nfkb1,Sqstm1,Nfkbia |
| 7.384e-03 | -4.91 | GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_UP | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_UP | 177 | 24 | 15632 | 1249 |
Cacna1d,Gys1,Kcna3,Aldh1b1,Pikfyve,Ptafr,Cx3cl1,Crkl,Psmb6,Cers6,Etv6,Acvrl1,Stat3,Pdlim7,Gpr35,Rbbp8,Ogfr,Atp6v1d,Eif4g2,Plod3,Tagln,Ikbkg,Ltbp2,Ccne1 |
| 7.384e-03 | -4.91 | GSE24210_IL35_TREATED_VS_UNTREATED_TCONV_CD4_TCELL_UP | MSigDB lists | GSE24210_IL35_TREATED_VS_UNTREATED_TCONV_CD4_TCELL_UP | 177 | 24 | 15632 | 1249 |
Cdc42ep2,Fbxo4,Rab3ip,Ehd1,Dse,Otud1,Arhgef3,Tet2,Egr2,Rab11fip1,D1Ertd622e,Hdac1,Cnot4,Uchl1,Mtmr14,Nsmaf,Usp42,Whamm,Igf1r,Tagap,Igsf9,Lcn2,Pstpip2,Ppp2r3a |
| 7.384e-03 | -4.91 | GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_DN | MSigDB lists | GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_DN | 177 | 24 | 15632 | 1249 |
Ccnd2,Cyth3,Sass6,Gmppb,Ppa1,Pkp4,Notch1,Chmp4b,Prpf38a,Gfi1,Pgk1,Tspo,Idi1,Lcp2,Txn1,Psat1,Cst7,Ccl5,Mid1,Gclm,Fut8,Cish,Peli1,Psme2 |
| 7.384e-03 | -4.91 | GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | MSigDB lists | GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | 177 | 24 | 15632 | 1249 |
Tbc1d1,Mdm2,Sdc2,Rsad2,Hlx,Ier2,Mxd1,Sell,Socs1,Mapkbp1,Batf,Cd80,Atp2b4,Plk2,Gna15,P2ry2,Ext1,Csf1,Slc7a5,Stoml1,Spint2,Nfil3,Gfi1,Keap1 |
| 7.384e-03 | -4.91 | GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | 177 | 24 | 15632 | 1249 |
Cdc42ep4,Spire1,Fscn1,Plek,Cav1,Irf8,Piezo1,Csf3,Rictor,Vasp,Aim2,Nck1,Fas,Evl,Tlr6,Icam1,Mpp7,Cdc42ep2,Hck,Src,Tnf,Bcl2l11,Jun,Prkce |
| 7.384e-03 | -4.91 | GSE14308_TH1_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_TH1_VS_INDUCED_TREG_UP | 177 | 24 | 15632 | 1249 |
Arid4a,Sipa1l1,Irf7,Casp4,Daam1,Slpi,Zc3h7a,Oas2,Traf3ip2,Dusp5,Tnfsf4,Dnajb4,Phf6,Crbn,Dnaja1,Katna1,Rab9,D1Ertd622e,Spry2,Gsr,Tapbp,Acvrl1,Trim12c,Fam133b |
| 7.384e-03 | -4.91 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_UP | 177 | 24 | 15632 | 1249 |
Gfi1,Dnase1l3,Trem1,Adam19,Extl2,Smc5,Cd200,Itga4,Marcksl1,Ptger4,Rasgrp1,Stat4,Ccl2,Stap1,Gpr35,Isg20,Lcn2,Osm,Marco,Lcp2,Nfkb1,Gypc,Dpy19l1,Ehd1 |
| 7.384e-03 | -4.91 | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN | 177 | 24 | 15632 | 1249 |
Ppp1r15a,Tnfsf14,Jarid2,Gpr132,Fabp7,Isg20,Btg2,Osgin2,Chic2,Rnf19b,Mtmr14,Il1b,H3f3b,Ehd1,Tra2a,Taf4b,Kcnj2,Jmjd6,Il1a,Fpr2,Tnfaip3,Cdc42ep2,Cd14,Pilra |
| 7.384e-03 | -4.91 | GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_DN | MSigDB lists | GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_DN | 177 | 24 | 15632 | 1249 |
Dyrk2,Socs3,Trib3,Nr4a3,Pdzd11,Dr1,Slfn3,Slfn4,Cnp,Ddit4,Btg2,Snx2,Casp2,Rhoh,Kdm4a,Slc16a1,Nfkbia,Psip1,Otud1,Tiparp,Micall2,Nfkbie,Errfi1,Psma6 |
| 7.387e-03 | -4.91 | P53_DN.V2_UP | MSigDB lists | P53_DN.V2_UP | 130 | 19 | 15632 | 1249 |
Osgin2,Ier3,Ch25h,Etv5,Relb,Tnfaip3,Il1rn,Sdc4,Cxcl1,Cd83,Clcf1,Ccl4,Sla,Nfkbia,Mmp13,Xaf1,Cd69,Ikzf1,Prkce |
| 7.387e-03 | -4.91 | GO_REGULATION_OF_CELL_CYCLE_ARREST | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE_ARREST | 94 | 15 | 15632 | 1249 |
Btg2,Cnot4,Ccnd1,Mdm2,Casp2,Atm,Plk2,Cenpj,Crlf3,Tnks1bp1,Cdkn1a,Plk3,Pml,Plagl1,Cdk5r1 |
| 7.392e-03 | -4.91 | LIF_OSM | smart domains | SM00080 | 2 | 2 | 9567 | 823 |
Osm,Lif |
| 7.392e-03 | -4.91 | IL6 | smart domains | SM00126 | 2 | 2 | 9567 | 823 |
Csf3,Il6 |
| 7.392e-03 | -4.91 | Zalpha | smart domains | SM00550 | 2 | 2 | 9567 | 823 |
Zbp1,Adar |
| 7.398e-03 | -4.91 | GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_UP | 158 | 22 | 15632 | 1249 |
Egr3,Crkl,Acvr1b,Map2k4,Arf4,Stau1,Prpf4,Rnf114,Tor1aip1,Timp1,Tnfsf14,Ascc3,Rab21,Nr3c1,Minpp1,Tlr1,Egr2,Rffl,Slc25a12,Cpd,Hat1,Eef1e1 |
| 7.398e-03 | -4.91 | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 158 | 22 | 15632 | 1249 |
Csf3r,Zmynd15,Dhrs9,Ogfrl1,Cish,D1Ertd622e,Irs2,St3gal6,Sell,Zfp281,Hhex,Zfp319,Ripk3,Cd14,Crlf3,Card6,Fcgr4,Tlr1,Glrx,Cd300lf,Plat,Asf1a |
| 7.398e-03 | -4.91 | GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_UP | 158 | 22 | 15632 | 1249 |
Tsku,Ap3m2,Zbtb5,Pim3,Whamm,Lipg,Rgs1,Usp42,Hif1a,Mmp25,Plk3,Rictor,Dcp1a,Dusp4,Btg2,Fchsd2,Zfp36,Arid5a,Pde4b,Nampt,Jarid2,Pik3r5 |
| 7.459e-03 | -4.90 | Protein_kinase_ATP_BS | interpro domains | IPR017441 | 375 | 40 | 19984 | 1430 |
Akt3,Kdr,Plk3,Mark2,Grk3,Pdgfrb,Src,Dyrk2,Map3k6,Met,Flt1,Map4k4,Fgr,Pim3,Axl,Pim1,Prkx,Ptk2,Sgk3,Acvrl1,Map2k4,Map2k1,Acvr1b,Ikbke,Nek6,Mapkapk2,Pim2,Tyk2,Syk,Igf1r,Tlk2,Lyn,Prkce,Sik3,Plk2,Hck,Eif2ak2,Ripk3,Jak2,Acvr1 |
| 7.474e-03 | -4.90 | proteasome core complex | cellular component | GO:0005839 | 19 | 5 | 20747 | 1409 |
Psmb8,Psmb9,Psmb6,Psma6,Psmb10 |
| 7.474e-03 | -4.90 | Integrin_alpha2 | pfam domains | PF08441 | 18 | 5 | 18711 | 1348 |
Itga9,Itgav,Itga4,Itgal,Itga5 |
| 7.474e-03 | -4.90 | FG-GAP | pfam domains | PF01839 | 18 | 5 | 18711 | 1348 |
Itga9,Itga5,Itga4,Itgal,Itgav |
| 7.482e-03 | -4.90 | thiol-dependent ubiquitinyl hydrolase activity | molecular function | GO:0036459 | 98 | 14 | 20217 | 1400 |
Usp53,Tnfaip3,Usp18,Vcpip1,Usp25,Otud1,Usp31,Tank,Usp35,Zup1,Zc3h12a,Usp12,Usp42,Uchl1 |
| 7.486e-03 | -4.89 | KRAS.300_UP.V1_UP | MSigDB lists | KRAS.300_UP.V1_UP | 121 | 18 | 15632 | 1249 |
Fabp3,Cdk5r1,St3gal6,Kif5c,Rtn1,Dcbld2,Etv5,Glrx,Adam19,Dock4,Trim36,Dusp6,Dhrs9,Csf3,Cxcl2,Spry2,Scn1b,Lrch1 |
| 7.486e-03 | -4.89 | GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST | MSigDB lists | GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST | 121 | 18 | 15632 | 1249 |
Trem1,Tnfaip3,Zc3hav1,Il15,Ddx58,Stat2,Il12b,Mul1,Aim2,Zc3h12a,Traf3ip2,Itpkc,Pml,Il12rb1,Leng9,Ifit1bl1,Fcgr4,Ifit1bl2 |
| 7.487e-03 | -4.89 | response to muscle stretch | biological process | GO:0035994 | 19 | 5 | 20694 | 1406 |
Slc9a1,Jun,Nfkbia,Fos,Nfkb1 |
| 7.487e-03 | -4.89 | negative regulation of natural killer cell mediated cytotoxicity | biological process | GO:0045953 | 19 | 5 | 20694 | 1406 |
Lgals9,Tap1,Tap2,Clec2d,Serpinb9 |
| 7.487e-03 | -4.89 | mitotic G1 DNA damage checkpoint | biological process | GO:0031571 | 19 | 5 | 20694 | 1406 |
Pml,Casp2,Mdm2,Cdkn1a,Ccnd1 |
| 7.487e-03 | -4.89 | regulation of interleukin-2 biosynthetic process | biological process | GO:0045076 | 19 | 5 | 20694 | 1406 |
Il1a,Zfp36,Il1b,Irf4,Stat5a |
| 7.487e-03 | -4.89 | regulation of ATP biosynthetic process | biological process | GO:2001169 | 19 | 5 | 20694 | 1406 |
Ak4,Myc,Pid1,Stat3,Map2k1 |
| 7.487e-03 | -4.89 | negative regulation of purine nucleotide metabolic process | biological process | GO:1900543 | 19 | 5 | 20694 | 1406 |
Stat3,Ddit4,Ier3,Nupr1,Pid1 |
| 7.487e-03 | -4.89 | positive regulation of hormone biosynthetic process | biological process | GO:0046886 | 19 | 5 | 20694 | 1406 |
Egr1,Tnf,Il1b,Hif1a,Igf1r |
| 7.532e-03 | -4.89 | HEATSHOCK70 | prints domains | PR00301 | 13 | 4 | 5821 | 374 |
Hsph1,Hspa1b,Hspa2,Hspa1a |
| 7.553e-03 | -4.89 | outflow tract morphogenesis | biological process | GO:0003151 | 80 | 12 | 20694 | 1406 |
Crkl,Cited2,Hif1a,Jun,Fzd1,Jag1,Sec24b,Sema3c,Nrp2,Thbs1,Acvr1,Notch1 |
| 7.554e-03 | -4.89 | HSF2_01 | MSigDB lists | HSF2_01 | 226 | 29 | 15632 | 1249 |
Nfkbid,Ube2e2,Pdgfb,Bcl9,Lap3,Eif4g2,Jarid2,Cacna1d,Pcdh7,Ralgds,Trib1,Clec4d,Nr4a3,Egr3,Rbpms,Mid1,Cish,Fos,Bcl6,Jun,Hspa1a,Hsph1,Dusp1,Hivep2,Abcc5,Me1,Tab2,Cdk5r1,Nek6 |
| 7.560e-03 | -4.88 | GO_REGULATION_OF_METAL_ION_TRANSPORT | MSigDB lists | GO_REGULATION_OF_METAL_ION_TRANSPORT | 286 | 35 | 15632 | 1249 |
Hap1,Scn1b,Slc9a1,Pdgfb,Pdgfrb,Cav1,Ccl5,Gja1,Pde4b,Slc31a2,Ccr1,Glrx,Ccl4,Cacna1d,Lyn,Adrb2,Cxcl10,Ptgs2,Cacnb3,Tlr9,Hspa2,Prkce,Kcnj2,Homer1,P2ry12,Ccl12,Atp2b4,Htr2a,Tspo,Sgk3,Slc30a1,Ubash3b,Prnp,Icam1,Pml |
| 7.579e-03 | -4.88 | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP | 187 | 25 | 15632 | 1249 |
Plac8,Nr4a1,Irf4,Casp3,Dusp2,Fgl2,Mcm10,Egr1,Fpr2,Clcn5,Rbl1,Snx10,Pdk3,S100a8,Txn1,Myadm,Irf8,Gem,Isg20,Hp,Dck,C3,Serpinb9,Lyn,Idi1 |
| 7.579e-03 | -4.88 | GSE45365_NK_CELL_VS_CD8A_DC_UP | MSigDB lists | GSE45365_NK_CELL_VS_CD8A_DC_UP | 187 | 25 | 15632 | 1249 |
Slc29a3,Clcn7,Fscn1,Snn,Rac3,Dck,Sema4a,Il2rg,Slpi,Ep400,Kctd12,Car13,Rnf31,Pdk3,Casp8,Lcn2,Lcp2,Col4a2,Hvcn1,Mxd1,Evl,Carhsp1,Dbnl,Fam43a,Zyx |
| 7.579e-03 | -4.88 | TTTGCAG_MIR518A2 | MSigDB lists | TTTGCAG_MIR518A2 | 187 | 25 | 15632 | 1249 |
Ankrd17,Hmga1,Kcnj2,Rab21,Ccl2,Aebp2,Cept1,Kdm5b,Dock10,Atp11a,Fam133b,Gnb4,Mier3,Dusp6,Mmd,Jag1,Cpeb4,Kpna3,Egr3,Pcgf5,Osgin2,Phf6,Chd9,Rap2c,Pmepa1 |
| 7.579e-03 | -4.88 | GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN | 187 | 25 | 15632 | 1249 |
Lipe,Spryd7,Psmb9,Rhoq,Slc44a1,Ccng2,Tapbp,Evl,Hhex,Pgm1,Traf5,Slc48a1,Klf7,Mdfic,Atm,Gna15,Pdgfrb,Caml,Btg2,Uba7,Tmem229b,Cox18,Tnip1,Tax1bp1,Cmpk2 |
| 7.579e-03 | -4.88 | GO_PROTEIN_AUTOPHOSPHORYLATION | MSigDB lists | GO_PROTEIN_AUTOPHOSPHORYLATION | 187 | 25 | 15632 | 1249 |
Syk,Src,Eif2ak2,Flt1,Fgr,Mapkapk2,Nek6,Irak3,Hck,Ripk3,Mark2,Pim3,Pdgfrb,Atm,Tyk2,Lyn,Acvr1b,Pim1,Pim2,Ptk2,Vrk2,Igf1r,Kdr,Prkx,Jak2 |
| 7.579e-03 | -4.88 | GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDC_UP | 187 | 25 | 15632 | 1249 |
Cd200,Ripk2,Rcsd1,Clcf1,Il15ra,Vrk2,Irf8,Csf1,Ccnd2,Atp11a,Cd34,Ciita,Tspo,Gbp2,Angpt1,Tagln,Bcl2l11,P2ry12,Hmga1,Phgdh,Oaf,Dusp2,Ccl2,Ly75,Psd |
| 7.579e-03 | -4.88 | GSE17721_CTRL_VS_POLYIC_1H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_1H_BMDC_DN | 187 | 25 | 15632 | 1249 |
Pde4b,Zc3h12c,Map2k1,Trim26,Atp10a,Dtx2,Cxcl10,Cflar,Cxcl1,Fscn1,Serpinb2,Tmem123,Slfn9,Nfil3,Tnf,N4bp1,Slc2a1,Slfn8,Fcgr2b,Ly75,Cpd,Hlx,Jmjd6,P2ry14,Rnd3 |
| 7.579e-03 | -4.88 | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | MSigDB lists | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | 187 | 25 | 15632 | 1249 |
Oas3,Rab32,Plac8,Dpy19l1,Gypc,Srm,Cst7,Spry2,Setdb2,Ubash3b,Rnf135,Mcoln2,Lrp8,Tor1aip1,Mmd,Oas2,Parp12,Inpp5b,Trim14,Pdlim7,Acvr1b,Mafg,Lyn,Adam19,Ppp2r1b |
| 7.579e-03 | -4.88 | GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP | MSigDB lists | GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP | 187 | 25 | 15632 | 1249 |
Tifa,H2-Aa,Ltbp2,Gch1,Myadm,Birc3,Atm,Plek,Irf8,Ripk2,Prdm9,Nr4a3,Tgfbi,Lpar1,Tnfsf8,Lrp4,Syk,Cst7,Plac8,Cd40,Tcf4,Swap70,Cd83,Ciita,Cd74 |
| 7.579e-03 | -4.88 | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN | 187 | 25 | 15632 | 1249 |
Il12rb1,Ksr1,Plscr1,Gem,Eif4g2,Glrx,Acp2,Tnfsf10,Adora2b,Usp42,Rnf19b,Dusp5,Chst11,Mlkl,Irgm2,Slc39a4,Ttc39c,Eif2ak2,Cst7,Cd38,Ahr,Slco3a1,Arl4a,Mpp7,Psme1 |
| 7.579e-03 | -4.88 | GSE13306_TREG_VS_TCONV_SPLEEN_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_SPLEEN_UP | 187 | 25 | 15632 | 1249 |
Dgkh,Ptprj,Ripk2,Mmp9,Pim1,Odc1,Serpinb9,Sec24a,Slc4a7,Procr,Isg20,Tlr1,Zscan29,Spint2,Csrnp1,Lif,Ccnd2,Ppm1l,Papss2,Sdc4,Trp53i11,Slfn5,Hivep2,Dusp4,C1ra |
| 7.602e-03 | -4.88 | regulation of muscle cell apoptotic process | biological process | GO:0010660 | 100 | 14 | 20694 | 1406 |
Zc3h12a,Sirt1,Bnip3,Il12b,Map2k4,Trip10,Jak2,Edn1,Igf1r,Nupr1,Hmox1,Sod2,Cav1,Cflar |
| 7.602e-03 | -4.88 | regulation of calcium-mediated signaling | biological process | GO:0050848 | 100 | 14 | 20694 | 1406 |
Tnf,Atp2b4,Syk,Bst1,Ccl4,Itpr1,Cmklr1,Kdr,Rcan1,Hap1,Slc9a1,Dyrk2,Itgal,Prnp |
| 7.615e-03 | -4.88 | SASSON_RESPONSE_TO_FORSKOLIN_DN | MSigDB lists | SASSON_RESPONSE_TO_FORSKOLIN_DN | 77 | 13 | 15632 | 1249 |
Stip1,Dusp14,Actb,Trp53i11,Thbs1,Trib1,Pik3cd,Stat1,Sh3bp4,Gem,Casp4,Axl,Map4k4 |
| 7.630e-03 | -4.88 | CSR_EARLY_UP.V1_UP | MSigDB lists | CSR_EARLY_UP.V1_UP | 149 | 21 | 15632 | 1249 |
Phlpp2,Pnp2,Spry2,Zfp800,Usp12,Inhba,Zfp324,Phldb1,Dnaja1,D16Ertd472e,Hmga1,Cd274,Slc16a1,Sec24a,Frmd6,Plaur,Ripk2,Hlx,St3gal1,Slc30a1,Ptgs2 |
| 7.630e-03 | -4.88 | GSE27896_HDAC6_KO_VS_WT_TREG_DN | MSigDB lists | GSE27896_HDAC6_KO_VS_WT_TREG_DN | 149 | 21 | 15632 | 1249 |
Ptger4,Malt1,Hmgcs1,Ddx58,Kmo,Trim13,Dtwd1,Traf1,Fgr,P2ry14,Tmem67,Extl2,Herc3,Tnfsf10,Ldlr,Clic4,Hsd17b7,Angpt1,Eif2ak2,Sesn3,Xaf1 |
| 7.631e-03 | -4.88 | regulation of translational initiation | biological process | GO:0006446 | 61 | 10 | 20694 | 1406 |
Klhl25,Ppp1r15a,Ythdf1,Nck1,Larp1,Ppp1r15b,Tnf,Eif4g2,Eif2ak2,Polr2g |
| 7.636e-03 | -4.87 | positive regulation of B cell mediated immunity | biological process | GO:0002714 | 43 | 8 | 20694 | 1406 |
C3,Nod2,Tnf,Clcf1,Nectin2,Tnfsf4,Fcgr1,Cd40 |
| 7.636e-03 | -4.87 | positive regulation of immunoglobulin mediated immune response | biological process | GO:0002891 | 43 | 8 | 20694 | 1406 |
Fcgr1,Cd40,Tnf,Clcf1,Nectin2,Tnfsf4,Nod2,C3 |
| 7.644e-03 | -4.87 | neural crest cell differentiation | biological process | GO:0014033 | 90 | 13 | 20694 | 1406 |
Hif1a,Sema4c,Htr2b,Ednrb,Edn1,Cited2,Phactr4,Nrp2,Sema3c,Jag1,Acvr1,Sema4a,Kitl |
| 7.644e-03 | -4.87 | negative regulation of hormone secretion | biological process | GO:0046888 | 90 | 13 | 20694 | 1406 |
Osm,Rab11fip1,Klf7,Pim3,Il1b,Pfkl,Lif,Pde3b,Map4k4,Il6,Hdac1,Sirt1,Edn1 |
| 7.676e-03 | -4.87 | GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_UP | 168 | 23 | 15632 | 1249 |
Cebpd,Errfi1,Lztfl1,Phldb1,Slc25a37,Rab32,Gramd1a,Gpr18,Slc16a1,Foxp4,Mapkapk2,Spata13,Rab10,Rasgrp1,Ube2e2,Sh3bp4,Tuba4a,P2ry2,Pcdh7,Gsta3,Gng12,Itga9,Mob3b |
| 7.691e-03 | -4.87 | ribonucleoprotein granule | cellular component | GO:0035770 | 208 | 24 | 20747 | 1409 |
Psma6,Ago3,Carhsp1,Socs1,Trim12c,Mov10,Larp1,Actb,Ddx4,Zc3h12a,Stau1,Rbpms,Tdrd7,Dcp2,Icosl,Dcp1a,Zfp36,Kif3c,Xrn1,Nfkbiz,Polr2g,Noct,Sqstm1,G3bp2 |
| 7.749e-03 | -4.86 | NUYTTEN_NIPP1_TARGETS_DN | MSigDB lists | NUYTTEN_NIPP1_TARGETS_DN | 755 | 79 | 15632 | 1249 |
Slc16a1,Slc48a1,Sgcb,Atp11b,Nlrp3,Kat2b,Dcp2,Sdc1,Rai14,Slc44a1,Kcnj2,Syk,Zyx,Dnaja1,Rhof,Tmem184b,Rap2c,Ppp2r1b,Actb,Znrf1,Fscn1,Arf4,Orai2,Lhx2,Dennd2a,Denr,Map2k4,Rcn1,Slpi,Ociad1,Syne2,Dcp1a,Pla2g7,Eif4g2,Lcn2,Cav1,Pbx1,Notch1,Malt1,Mxd1,Ccdc86,Casp3,Gpr68,Ccng2,Cers6,Ccnd1,Spryd7,Plekhf2,Parp8,Ankrd17,Osbpl3,Snapc1,Elmod2,Plcl2,Ptges,Keap1,Igf2bp2,Dusp5,St3gal1,Mcm6,Adora2b,Slc43a3,4930453N24Rik,Phlda1,Antxr1,Rab10,Pdgfb,Maff,Spint2,Vasn,Map4k4,Tuba4a,Gch1,Ttc9c,Snx10,Fubp1,Igsf8,Golga3,Klf2 |
| 7.752e-03 | -4.86 | GO_POSITIVE_REGULATION_OF_LIPID_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_LIPID_KINASE_ACTIVITY | 37 | 8 | 15632 | 1249 |
Fgr,Pdgfrb,Lyn,Ptk2,Flt1,Src,Nod2,Pdgfb |
| 7.752e-03 | -4.86 | BIOCARTA_MET_PATHWAY | MSigDB lists | BIOCARTA_MET_PATHWAY | 37 | 8 | 15632 | 1249 |
Met,Stat3,Jun,Map2k1,Fos,Ptk2,Crkl,Src |
| 7.783e-03 | -4.86 | Ddx60 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 60) | protein interactions | 234311 | 5 | 3 | 7778 | 753 |
Dhx58,Ifih1,Ddx58 |
| 7.783e-03 | -4.86 | Tmem173 (transmembrane protein 173) | protein interactions | 72512 | 5 | 3 | 7778 | 753 |
Trim56,Usp18,Trim30a |
| 7.783e-03 | -4.86 | Tirap (toll-interleukin 1 receptor (TIR) domain-containing adaptor protein) | protein interactions | 117149 | 5 | 3 | 7778 | 753 |
Socs1,Myd88,Tnfsf9 |
| 7.783e-03 | -4.86 | MRPL4 (mitochondrial ribosomal protein L4) | protein interactions | 51073 | 5 | 3 | 7778 | 753 |
Brwd3,Cenpe,Samhd1 |
| 7.783e-03 | -4.86 | RALA (RAS like proto-oncogene A) | protein interactions | 5898 | 5 | 3 | 7778 | 753 |
Tmod3,Flnb,Actb |
| 7.783e-03 | -4.86 | Bcl2a1a (B cell leukemia/lymphoma 2 related protein A1a) | protein interactions | 12044 | 5 | 3 | 7778 | 753 |
Pmaip1,Bcl2l11,Rel |
| 7.783e-03 | -4.86 | Tapbp (TAP binding protein) | protein interactions | 21356 | 5 | 3 | 7778 | 753 |
Tap1,Tap2,H2-Aa |
| 7.783e-03 | -4.86 | Ltbr (lymphotoxin B receptor) | protein interactions | 17000 | 5 | 3 | 7778 | 753 |
Traf2,Birc3,Traf5 |
| 7.783e-03 | -4.86 | Mapk9 (mitogen-activated protein kinase 9) | protein interactions | 26420 | 5 | 3 | 7778 | 753 |
Mapkbp1,Lrp8,Dusp2 |
| 7.783e-03 | -4.86 | Trpc4 (transient receptor potential cation channel, subfamily C, member 4) | protein interactions | 22066 | 5 | 3 | 7778 | 753 |
Cav1,Itpr1,Cyfip1 |
| 7.783e-03 | -4.86 | RFC3 (replication factor C subunit 3) | protein interactions | 5983 | 5 | 3 | 7778 | 753 |
Brwd3,Ksr1,Rrbp1 |
| 7.817e-03 | -4.85 | PROTEASOME_BETA_1 | prosite domains | PS00854 | 11 | 4 | 13278 | 1037 |
Psmb10,Psmb6,Psmb8,Psmb9 |
| 7.817e-03 | -4.85 | PROTEASOME_BETA_2 | prosite domains | PS51476 | 11 | 4 | 13278 | 1037 |
Psmb10,Psmb8,Psmb9,Psmb6 |
| 7.826e-03 | -4.85 | GO_VACUOLAR_PART | MSigDB lists | GO_VACUOLAR_PART | 635 | 68 | 15632 | 1249 |
Ehd1,Plekhf2,H2-Q6,Acpp,Rab21,Slc15a3,Rffl,Slc39a4,Cp,Slc30a4,H2-Q7,Pml,Tab2,Cd74,Atp11a,Gnb4,Myd88,Cd14,Clcn5,Cd164,Snx10,H2-Eb1,Fzd5,Myo1b,Rnaset2a,Atp6v1d,Pdgfrb,Irf7,Rab10,Inpp5b,H2-Aa,Antxr1,Snx2,Vasn,Tlr3,H2-Ab1,Scyl2,Ikbke,Irak2,Mitd1,Slc29a3,Acp2,H2-Q4,Rab32,Agrn,Irgm2,Sdc2,Ap3b1,Vcan,Sdc1,Pikfyve,Sdc4,Gpc1,Fcgr1,Slc48a1,Chmp4b,Atp11b,Lnpep,Cav1,Mmd,Tlr9,Dram1,Jak2,Clcn7,Ldlr,Rap2c,Rnaset2b,Pmepa1 |
| 7.837e-03 | -4.85 | GO_REGULATION_OF_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 140 | 20 | 15632 | 1249 |
Psmd10,Plk2,Cav1,Dusp1,Atm,Ankib1,Rnf114,Rnf14,N4bp1,Rnf19a,Tlk2,Mdm2,Trib1,Trib3,Rnf19b,Plk3,Smc5,Keap1,Dnajb2,Gclc |
| 7.861e-03 | -4.85 | MAZR_01 | MSigDB lists | MAZR_01 | 207 | 27 | 15632 | 1249 |
Abr,Mthfr,Apba1,Zfp513,Etv5,Stau1,Rbl1,Ahr,Trip10,Hmga1,Vcan,Tlk2,Mllt6,Aebp2,Dusp8,Pim1,Sema4c,Nlgn2,Notch2,Gtpbp2,Ust,Rap2c,Mov10,Junb,Vasp,Rtn2,Med13 |
| 7.862e-03 | -4.85 | Traf2 (TNF receptor-associated factor 2) | protein interactions | 22030 | 25 | 7 | 7778 | 753 |
Birc3,Ikbkg,Cd40,Tifa,Tnfaip3,Mapkbp1,Tax1bp1 |
| 7.863e-03 | -4.85 | - | gene3d domains | 3.40.50.10140 | 28 | 7 | 8819 | 755 |
Tlr2,Tlr6,Tlr3,Tlr9,Il18rap,Myd88,Tlr1 |
| 7.880e-03 | -4.84 | nucleoside-triphosphatase regulator activity | molecular function | GO:0060589 | 295 | 32 | 20217 | 1400 |
Rgs1,Gpsm2,Arhgap26,Htr2b,Dnaja2,Adap2,Tagap,Rap1gap2,Tbc1d1,Ralgds,Tor1aip2,Agrn,Rapgef2,Jun,Dnajb4,Tor1aip1,Rgs14,Abr,Cdc42ep2,Asap3,Sipa1l1,Rgs3,Ranbp2,Elmod2,Ahsa1,Tbc1d13,Dock4,Dnaja1,Sh3bp4,Rin2,Hsph1,Dnajb2 |
| 7.899e-03 | -4.84 | Cellular responses to stress | REACTOME pathways | R-MMU-2262752 | 356 | 45 | 8608 | 757 |
Psma6,Psme2,Sirt1,Ube2e1,Psmb8,Mdm2,Chmp4b,Txnrd1,Psmb6,Psme1,Ranbp2,H3f3b,Cited2,Hsph1,Ets2,Egln3,Ccne1,Mtmr14,Fos,Ep400,Cdkn1a,Txn1,Prdx1,Asf1a,Cdkn2d,Hmga1,Hspa1b,Psmd10,Gsr,Kdm6b,Psmb10,Cycs,Jun,Psmb9,Hif1a,Mapkapk2,Il6,Sod2,Psme2b,Map2k4,Nfkb1,Atm,Prdx5,Ero1l,Hmga2 |
| 7.908e-03 | -4.84 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_UP | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_UP | 178 | 24 | 15632 | 1249 |
Lmo4,Pde4b,Dgka,Cnn3,H2-Aa,Slpi,Acvr1b,Rnf145,Gpd2,Nr4a3,Dyrk2,Snn,Ppp2r1b,Ikbke,Gpr18,Gramd1a,Spsb1,Ccnd1,Acvrl1,Ppp2r5a,Kmo,Myo10,Dnase1l3,Pde3b |
| 7.908e-03 | -4.84 | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_UP | 178 | 24 | 15632 | 1249 |
Snx2,Uba7,Ube2l6,Spen,Cep350,Tor3a,Ahrr,Nfil3,Tmem229b,Slamf8,Ms4a6d,Asb13,Etnk1,Traf3ip2,Atp13a1,D1Ertd622e,Rab9,Ccl2,Jun,Trmt1l,Gypc,Pdgfc,Nxf1,Hlx |
| 7.908e-03 | -4.84 | GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP | MSigDB lists | GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP | 178 | 24 | 15632 | 1249 |
Ddx60,Cd55,Ddx58,Usp18,Slc30a1,Plcl2,Zcchc2,Pde3b,Zc3hav1,Abcc4,Ifit1bl1,Ifit1bl2,Ccl5,Mtus1,D16Ertd472e,Casp4,Bnip3,Fut8,St3gal5,Acvr1,Ccdc25,Stat4,Optn,Cpd |
| 7.908e-03 | -4.84 | GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | 178 | 24 | 15632 | 1249 |
Rab20,Pik3cd,Wdr43,Asf1a,Sipa1l1,Plod2,Jarid2,Rasgrp1,Stx6,Uba7,Zfp36,Cdk5r1,Il4ra,Ube2e1,Tnfrsf14,Mrpl52,Cst7,Phldb1,Gsdmd,Cers6,Nfkbie,S1pr2,Slc39a4,Tnfsf8 |
| 7.908e-03 | -4.84 | GSE14350_IL2RB_KO_VS_WT_TEFF_UP | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TEFF_UP | 178 | 24 | 15632 | 1249 |
Parp3,Tnfsf4,Nfkb2,Slc29a3,Znrf1,Zhx2,Igf1r,Lnpep,S100a8,Psme2,Wdfy1,Sh3bp4,Mcoln2,Marcksl1,Ifih1,Cd74,Plagl1,Batf,Hvcn1,Ncoa7,Parp8,Tspan3,Prkce,Tnfsf8 |
| 7.908e-03 | -4.84 | GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_DN | MSigDB lists | GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_DN | 178 | 24 | 15632 | 1249 |
Rnf31,Csrp1,Hk2,Arl5b,Tlr2,Ap3m2,Polr2g,Cited2,Hspa1a,Dnaja1,Psmb9,Fam43a,Mafk,Cox17,Trim12c,Rnf135,Arl4a,Psmb10,Fam133b,Coa5,Nkiras1,Tpi1,Plk3,Cd38 |
| 7.908e-03 | -4.84 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | 178 | 24 | 15632 | 1249 |
Ext1,Slc44a1,Tlr1,Treml2,Rap1gap2,Map4k4,Mtus1,Arhgef3,Klf2,Cd40,Dock4,Tcf4,Sh3bgrl2,Ikbke,Chd9,Tmem219,Klf7,Snn,Itga4,Smox,Rhoh,Ubash3b,Calcrl,Sell |
| 7.908e-03 | -4.84 | GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_DN | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_DN | 178 | 24 | 15632 | 1249 |
Rtp4,Rnd3,Me1,Cited2,Tspan3,Rhoq,Gclm,Ctsc,Dock10,Acvr1,Ifrd1,Ldha,Tapbpl,Rcn1,Adora2b,Ptgs2,Asf1a,Keap1,Pgk1,Wdr43,Mfap3l,Map2k1,C1rl,Asns |
| 7.908e-03 | -4.84 | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_DN | 178 | 24 | 15632 | 1249 |
Irf7,Ptch1,Lmo4,Itgal,Ppp1r15a,Gna15,Pim1,H2-Ab1,Acp2,Tnfaip2,Ldlr,Clic4,Pcdh7,Clcn7,Tmem184b,Cd40,Ppp6r1,Itgav,Pla2g4a,Nlrp3,Tab2,Enpp4,Tspo,Ahsa1 |
| 7.908e-03 | -4.84 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 178 | 24 | 15632 | 1249 |
Csf3,Uba7,Klf2,Pde4b,Ap3m2,Tnip1,Pim1,Pik3cd,Cd55,Mdn1,Slc15a3,Ly75,Timp1,B4galt4,Serp1,Ehd1,Sqstm1,Dhrs9,Tnfrsf14,Mvp,Ccnd2,Il4ra,Asap3,Tlr6 |
| 7.911e-03 | -4.84 | negative regulation of cell development | biological process | GO:0010721 | 384 | 39 | 20694 | 1406 |
Mdm2,Tomm70a,Ednrb,Dync1i2,Ptk2,Gfi1,Il15ra,Hmga2,Notch1,Prag1,Il1b,Ifrd1,Rap1gap2,Sema4c,Stap1,Kremen1,Cav1,Zhx2,Fas,Cdk5r1,Pbx1,Cd38,Sema3c,Plk2,Rapgef2,Lhx2,Map4k4,Stat3,Sema4a,Katna1,Ldlr,Kdm4a,Mecp2,Casz1,Lrp4,Tspo,Lpar1,Jag1,Il1a |
| 7.938e-03 | -4.84 | CALPONIN_2 | prosite domains | PS51122 | 6 | 3 | 13278 | 1037 |
Cnn2,Cnn3,Tagln |
| 7.938e-03 | -4.84 | CALPONIN_1 | prosite domains | PS01052 | 6 | 3 | 13278 | 1037 |
Cnn2,Cnn3,Tagln |
| 7.938e-03 | -4.84 | negative regulation of neuron projection development | biological process | GO:0010977 | 175 | 21 | 20694 | 1406 |
Il15ra,Dync1i2,Ptk2,Gfi1,Sema4a,Katna1,Prag1,Sema3c,Cd38,Mdm2,Map4k4,Rapgef2,Plk2,Lrp4,Lpar1,Kremen1,Cdk5r1,Mecp2,Rap1gap2,Ifrd1,Sema4c |
| 7.938e-03 | -4.84 | ameboidal-type cell migration | biological process | GO:0001667 | 175 | 21 | 20694 | 1406 |
P2ry12,Kitl,Syne2,Phactr4,Sema4c,Hif1a,Kdr,Htr2b,Itgav,Sema4a,Ptk2,Pml,Prkx,Acvr1,Nr4a1,Arid5b,Itga4,Sema3c,Nrp2,Egr3,Ednrb |
| 7.943e-03 | -4.84 | GO_NATURAL_KILLER_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_NATURAL_KILLER_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 23 | 6 | 15632 | 1249 |
Ifna6,Ifna1,Ifna2,Ifnb1,Ifna5,Il12b |
| 7.943e-03 | -4.84 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN | 23 | 6 | 15632 | 1249 |
Rbms1,Eif2ak2,Brd2,Myc,Fpr2,Fos |
| 7.943e-03 | -4.84 | GO_RESPONSE_TO_CORTICOSTERONE | MSigDB lists | GO_RESPONSE_TO_CORTICOSTERONE | 23 | 6 | 15632 | 1249 |
Fosb,Cdkn1a,Fos,Ccnd1,Ccne1,Junb |
| 7.943e-03 | -4.84 | CLIMENT_BREAST_CANCER_COPY_NUMBER_UP | MSigDB lists | CLIMENT_BREAST_CANCER_COPY_NUMBER_UP | 23 | 6 | 15632 | 1249 |
Ccnd1,Jag1,Bcl6,Ext1,Sla,Myc |
| 7.943e-03 | -4.84 | GO_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | MSigDB lists | GO_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 23 | 6 | 15632 | 1249 |
Edn1,Htr2a,Pik3r5,Igf1r,Htr2b,Pik3cd |
| 7.943e-03 | -4.84 | BIOCARTA_CELLCYCLE_PATHWAY | MSigDB lists | BIOCARTA_CELLCYCLE_PATHWAY | 23 | 6 | 15632 | 1249 |
Cdkn1a,Rbl1,Ccnd1,Cdkn2d,Ccne1,Ccnd2 |
| 7.943e-03 | -4.84 | GO_NEGATIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY | 23 | 6 | 15632 | 1249 |
Hp,Nfkb1,Atp2b4,Cav1,Prdx5,Gfi1 |
| 7.943e-03 | -4.84 | AZARE_STAT3_TARGETS | MSigDB lists | AZARE_STAT3_TARGETS | 23 | 6 | 15632 | 1249 |
Ccnd2,G3bp2,Thbs1,Clic4,Tnc,Pcdh7 |
| 7.943e-03 | -4.84 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN | 23 | 6 | 15632 | 1249 |
Osm,Tgfbi,Lif,Rapgef5,S100a8,Fcgr2b |
| 7.943e-03 | -4.84 | KEGG_ASTHMA | MSigDB lists | KEGG_ASTHMA | 23 | 6 | 15632 | 1249 |
Il10,Cd40,H2-Ab1,Tnf,H2-Eb1,H2-Aa |
| 7.943e-03 | -4.84 | GO_RESPONSE_TO_MAGNESIUM_ION | MSigDB lists | GO_RESPONSE_TO_MAGNESIUM_ION | 23 | 6 | 15632 | 1249 |
Sphk1,Ccnd1,Mdm2,C3,Thbs1,Cd14 |
| 7.943e-03 | -4.84 | GO_REGULATION_OF_METANEPHROS_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_METANEPHROS_DEVELOPMENT | 23 | 6 | 15632 | 1249 |
Pdgfrb,Egr1,Stat1,Lif,Myc,Pdgfb |
| 7.943e-03 | -4.84 | GO_POSITIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | MSigDB lists | GO_POSITIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | 23 | 6 | 15632 | 1249 |
Fam162a,Plaur,Bnip3,Tnfsf10,Mmp9,Bcl2l11 |
| 7.980e-03 | -4.83 | GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | MSigDB lists | GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 789 | 82 | 15632 | 1249 |
Socs1,Trim12c,Psmb10,Rnf135,Dtx3l,Ifih1,Usp18,Rnf139,Pml,Psme1,Ube2e1,Malt1,Tnfaip3,Ube2f,Rnf34,Bfar,Traf5,Birc2,Otud1,Psmb9,Traf2,Klhl25,Ctu1,Usp53,Psma6,Mdm2,Cish,Rffl,Rnf24,Egr2,Usp42,Zc3h12a,Uchl1,Psmb6,Smc5,Usp31,Rnf19b,Herc6,Keap1,Med21,Usp35,Uba7,Ube2l6,Znrf3,Mul1,Pttg1,Trim13,Bcor,Usp25,Vcpip1,Fbxo4,Herc3,Psmd10,Nlrc4,Rnf114,Crbn,Spsb1,Trim36,Cnot4,Peli1,Asb13,Rnf145,Dtx2,Socs3,Socs7,Znrf1,Ubr4,Dcun1d3,Rnf31,Lnpep,Rnf14,Rabgef1,Psmb8,Birc3,Ankib1,Trim56,Ube2e2,Sirt1,Rnf19a,Usp12,Psme2,Trim21 |
| 7.990e-03 | -4.83 | CPM (carboxypeptidase M) | protein interactions | 1368 | 14 | 5 | 7778 | 753 |
Actb,Rmdn3,Flnb,Chmp4b,Tmod3 |
| 7.990e-03 | -4.83 | TP53 (tumor protein p53) | protein interactions | 7157 | 14 | 5 | 7778 | 753 |
Sirt1,Ifi211,Mdm2,Pml,Hif1a |
| 7.993e-03 | -4.83 | CAGTATT_MIR200B_MIR200C_MIR429 | MSigDB lists | CAGTATT_MIR200B_MIR200C_MIR429 | 432 | 49 | 15632 | 1249 |
Zeb1,Cnn3,Ppp4r2,Med13,Mmd,Dach1,Gem,Cep350,Asf1a,Chd9,Rap2c,Prkar2b,Fignl2,Egr3,Dyrk2,Mafg,Kcnj2,Cnot4,Sdc2,Psip1,Cited2,Rnd3,Usp25,Kat2b,Pikfyve,Nrp2,Dgka,Ccnj,Rgl1,Cdyl,Map4k4,Plk2,Pcdh7,Clic4,Crkl,Phf6,Rab21,Nr3c1,Errfi1,Aebp2,Cers6,Dusp1,Phldb1,Lrp4,Itpr1,Mtus1,Ncoa7,Etv5,Prdm1 |
| 8.050e-03 | -4.82 | INTEGRIN_ALPHA | prosite domains | PS00242 | 17 | 5 | 13278 | 1037 |
Itgav,Itgal,Itga9,Itga4,Itga5 |
| 8.061e-03 | -4.82 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | 237 | 30 | 15632 | 1249 |
Slc7a11,Fam43a,Klf3,Fchsd2,Lrch1,Egr2,Rab11fip1,Casp3,Oaf,Kmo,Spata13,Icam1,Fas,Klf2,Zc3h12c,Gch1,Dusp6,Kctd12,Syne2,Etv6,Jag1,St3gal5,Nmi,Sap30,Ube2l6,Ksr1,Gpd2,Trib1,Rnf19b,Cmpk2 |
| 8.099e-03 | -4.82 | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | 188 | 25 | 15632 | 1249 |
Stip1,Cldnd1,Stat1,St3gal1,Etv6,Tlr1,Gpr132,Inpp5b,Sipa1l1,Hopx,Psd4,Sla,Traf5,Rras2,Nxf1,Slc30a4,Cox17,Dbnl,Ppp2r5a,Ctsc,Hspa1a,Dnaja1,Mrpl52,Plac8,Cnn2 |
| 8.099e-03 | -4.82 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | 188 | 25 | 15632 | 1249 |
Agrn,Dpy19l1,Lztfl1,Kdm5b,Rab11fip1,Sphk1,Etv3,Fpr2,Nek6,Tspo,F10,Sgcb,Fosb,Cxcl10,Ier3,Phyh,Tgfbi,Cacnb3,Ppa1,Smox,Il1b,Gfi1,Hcar2,Tax1bp1,Arf4 |
| 8.099e-03 | -4.82 | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN | 188 | 25 | 15632 | 1249 |
Maff,Eef1e1,Rasgrp1,Adora2a,Rab10,Serpine1,Tnfrsf1b,Abcc1,Rcl1,Dcbld2,Clcf1,Acsl5,Tlr2,Kcna3,Ptprj,Dusp2,Sqstm1,Olr1,Tnfaip3,Clcn5,Gpc1,Pilra,Slc25a25,Nck1,Prdm1 |
| 8.099e-03 | -4.82 | GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY7_UP | MSigDB lists | GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY7_UP | 188 | 25 | 15632 | 1249 |
Tpi1,Usp18,Ifih1,Herc3,Ifit1,Slfn5,Ifit2,Eif2ak2,Ezr,Trip10,Slfn8,Minpp1,Phlpp1,Rsad2,Max,Herc6,Trib1,Slc25a22,Slfn9,Pfkl,Cmpk2,Tor3a,Gna15,Irf7,Xaf1 |
| 8.099e-03 | -4.82 | GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN | MSigDB lists | GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN | 188 | 25 | 15632 | 1249 |
Il2rg,Wdr43,Bcl2a1a,Cxcl1,Lmo4,Plod2,Tnfsf14,Eno2,Stx6,Cxcl2,Reps1,Sap30,Dcp2,Nupr1,Irak3,Me1,Msr1,Fos,Bcl2a1b,Rab32,Bcl2a1d,Dtnb,Pcx,Acvr1,Vcan |
| 8.112e-03 | -4.81 | HSP70_C_sf | interpro domains | IPR029048 | 12 | 4 | 19984 | 1430 |
Hspa2,Hspa1b,Hspa1a,Hsph1 |
| 8.112e-03 | -4.81 | HSP70_peptide-bd_sf | interpro domains | IPR029047 | 12 | 4 | 19984 | 1430 |
Hsph1,Hspa1a,Hspa2,Hspa1b |
| 8.112e-03 | -4.81 | Proteasome_bsu_CS | interpro domains | IPR016050 | 12 | 4 | 19984 | 1430 |
Psmb6,Psmb8,Psmb10,Psmb9 |
| 8.128e-03 | -4.81 | chr9p22 | MSigDB lists | chr9p22 | 30 | 7 | 15632 | 1249 |
Ifna2,Ifna5,Ifnb1,Ifna6,Ifna1,Ttc39b,Psip1 |
| 8.128e-03 | -4.81 | GO_PROTEIN_COMPLEX_INVOLVED_IN_CELL_ADHESION | MSigDB lists | GO_PROTEIN_COMPLEX_INVOLVED_IN_CELL_ADHESION | 30 | 7 | 15632 | 1249 |
Itga5,Itgav,Itga4,Lyn,Itgal,Itga9,Itgb8 |
| 8.128e-03 | -4.81 | GO_POSITIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION | 30 | 7 | 15632 | 1249 |
Stau1,Notch1,Adar,Larp1,Ifit1bl2,Ifit1bl1,Ccl5 |
| 8.128e-03 | -4.81 | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | MSigDB lists | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | 30 | 7 | 15632 | 1249 |
Ccnd1,Pdgfrb,Jun,Bcl6,Fas,Nfkb1,Hmox1 |
| 8.128e-03 | -4.81 | GO_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION | MSigDB lists | GO_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION | 30 | 7 | 15632 | 1249 |
Sphk1,Ppp1r15a,Ripk2,Spred1,S1pr2,Ddit4,Spry2 |
| 8.128e-03 | -4.81 | GO_CELLULAR_SENESCENCE | MSigDB lists | GO_CELLULAR_SENESCENCE | 30 | 7 | 15632 | 1249 |
Cdkn1a,Sirt1,Pml,Smc5,Map2k1,Hmga1,Cav1 |
| 8.128e-03 | -4.81 | GO_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 30 | 7 | 15632 | 1249 |
Hmox1,Syk,Rabgef1,Il4ra,Lyn,Fgr,Adora2b |
| 8.128e-03 | -4.81 | WANG_METASTASIS_OF_BREAST_CANCER_ESR1_DN | MSigDB lists | WANG_METASTASIS_OF_BREAST_CANCER_ESR1_DN | 30 | 7 | 15632 | 1249 |
Il18,Phf11d,C3,Phf11b,Phf11c,Dusp4,Phf11a |
| 8.133e-03 | -4.81 | NFE2L2.V2 | MSigDB lists | NFE2L2.V2 | 380 | 44 | 15632 | 1249 |
Tnfsf15,4930523C07Rik,Asns,Uchl1,Smc5,Hmox1,H2-Ab1,Itgb8,Phgdh,Cycs,Gsr,Acvrl1,Phldb1,Txnrd1,Mdfic,Tsku,Hvcn1,Nupr1,Mcm10,Srxn1,Stat4,Jdp2,Psat1,Lcn2,Il10,Asf1a,Kif5c,Mthfd2,Mafg,Tnip3,Gclm,Nqo1,Slc7a11,Syk,Sqstm1,Bcl2l11,Flt1,Spn,Gclc,Slc48a1,Gpc1,Me1,Palld,Lrp8 |
| 8.133e-03 | -4.81 | MODULE_60 | MSigDB lists | MODULE_60 | 380 | 44 | 15632 | 1249 |
Hmox1,Ifi35,H2-Ab1,Ier3,Tgfbi,Trib1,Hcls1,Tnfaip2,Cdkn1a,Tnfrsf1b,Ccl5,Ccr1,Pdgfrb,Ppp1r15a,Scn1b,Alas1,Ube2l6,Ddit4,Stoml1,Mthfr,Nfkbil1,Plk3,Isg15,Psmb10,Cdk5r1,Fgr,Fpr2,Ccnd2,Cd14,Pbx1,Trp53i11,Plau,Cd34,Tap1,Rgs3,Tnfrsf14,Ccl12,Cst7,Nr4a1,Zyx,Cited2,Slc2a1,Rbpms,Ccnd1 |
| 8.143e-03 | -4.81 | GO_PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY | 95 | 15 | 15632 | 1249 |
Dusp1,Dusp6,Ptpn2,Map2k1,Dusp8,Dusp2,Eya4,Dusp4,Mtmr14,Ptprj,Dusp5,Ubash3b,Dusp16,Dusp28,Dusp14 |
| 8.174e-03 | -4.81 | chaperone binding | molecular function | GO:0051087 | 99 | 14 | 20217 | 1400 |
Cp,Dnaja2,Ctsc,Ksr1,Prnp,Ahr,Dnajb4,Pdpn,Birc2,Dnaja1,Dnajb2,Ahsa1,Hspa2,Stip1 |
| 8.174e-03 | -4.81 | ubiquitinyl hydrolase activity | molecular function | GO:0101005 | 99 | 14 | 20217 | 1400 |
Vcpip1,Usp18,Tank,Usp31,Otud1,Usp25,Tnfaip3,Usp53,Uchl1,Zc3h12a,Zup1,Usp35,Usp42,Usp12 |
| 8.216e-03 | -4.80 | mouse chr9|9 A1 | chromosome location | mouse chr9|9 A1 | 39 | 7 | 24173 | 1464 |
Tmem123,Maml2,Birc3,Sesn3,Endod1,Birc2,Mmp13 |
| 8.216e-03 | -4.80 | mouse chr8|8 C5 | chromosome location | mouse chr8|8 C5 | 39 | 7 | 24173 | 1464 |
Nlrc5,Lpcat2,9330175E14Rik,Ccl22,Ciapin1,Zfp319,Usb1 |
| 8.224e-03 | -4.80 | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP | 150 | 21 | 15632 | 1249 |
St3gal5,Rap1gap2,Cers6,Maff,Map4k4,Dusp1,Parp8,Plek,Otud1,Fos,Socs3,Nfkbiz,Mxd1,Ier2,Itga4,Fam111a,Irs2,Kcna3,Pim1,F11r,Ubash3b |
| 8.227e-03 | -4.80 | GO_NEGATIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT | 104 | 16 | 15632 | 1249 |
Zc3h12a,Dyrk2,Parp10,Nfkbil1,Nlrp3,Mdfic,Keap1,Angpt1,Nfkbia,Txn1,Il10,Psmd10,Nfkbib,Fzd1,Nfkbie,G3bp2 |
| 8.227e-03 | -4.80 | MODULE_192 | MSigDB lists | MODULE_192 | 104 | 16 | 15632 | 1249 |
Sp110,Pfkfb3,Osgin2,Frmd4a,Cxcl10,Ifi35,Snx2,Cebpd,Dusp4,Ccng2,Gclm,Zeb1,Cish,Timp1,Hspa1a,Crbn |
| 8.234e-03 | -4.80 | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP | MSigDB lists | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP | 169 | 23 | 15632 | 1249 |
Tnip3,Rcn1,Ebi3,Ptk2,Ppa1,Nfil3,Snapc1,Arf4,Ccl4,Cd82,Rgs1,Tnfsf14,Csf1,Prnp,Tle3,Cd83,Sla,Homer1,Ezr,Phldb1,Irf4,Tgs1,Gpr35 |
| 8.237e-03 | -4.80 | regulation of cellular response to drug | biological process | GO:2001038 | 35 | 7 | 20694 | 1406 |
Txn1,Glrx,Nr4a3,Il10,Met,Hk3,Hsph1 |
| 8.237e-03 | -4.80 | 'de novo' posttranslational protein folding | biological process | GO:0051084 | 35 | 7 | 20694 | 1406 |
Cd74,Hspa1b,Dnajb4,Hspa1a,Hsph1,Ero1l,Hspa2 |
| 8.237e-03 | -4.80 | glycosaminoglycan biosynthetic process | biological process | GO:0006024 | 35 | 7 | 20694 | 1406 |
Ext1,Pdgfrb,Angpt1,Extl2,Dse,Il1b,Chst11 |
| 8.274e-03 | -4.79 | GO_POSITIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 45 | 9 | 15632 | 1249 |
Ptpn2,Cav1,Bcl2l11,Nck1,Nox1,S100a8,Plagl2,Ripk3,Sirt1 |
| 8.274e-03 | -4.79 | SRF_01 | MSigDB lists | SRF_01 | 45 | 9 | 15632 | 1249 |
Egr1,Junb,Egr3,Ier2,Cnn2,Fosb,Fos,Thbs1,Egr2 |
| 8.274e-03 | -4.79 | GO_NEURON_DEATH | MSigDB lists | GO_NEURON_DEATH | 45 | 9 | 15632 | 1249 |
Bnip3,Slc9a1,Casp3,Plau,Fam162a,Apaf1,Fas,Max,Atm |
| 8.274e-03 | -4.79 | REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 | MSigDB lists | REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 | 45 | 9 | 15632 | 1249 |
Psmb10,Psmb9,Psmd10,Psmb6,Psmb8,Atm,Psme1,Psma6,Psme2 |
| 8.274e-03 | -4.79 | SESTO_RESPONSE_TO_UV_C5 | MSigDB lists | SESTO_RESPONSE_TO_UV_C5 | 45 | 9 | 15632 | 1249 |
Ldlr,Myc,Ext1,Sdc4,Abcc1,Jag1,Stat1,Eif2ak2,Rbbp8 |
| 8.289e-03 | -4.79 | positive regulation of response to DNA damage stimulus | biological process | GO:2001022 | 101 | 14 | 20694 | 1406 |
Parp9,Spire1,Eef1e1,Spred1,Atm,Pmaip1,Parp3,Spred3,Eya4,Dtx3l,Myc,Timeless,Plscr1,Sirt1 |
| 8.292e-03 | -4.79 | LEE_LIVER_CANCER_DENA_UP | MSigDB lists | LEE_LIVER_CANCER_DENA_UP | 61 | 11 | 15632 | 1249 |
Bcl2a1d,Tlr1,Lcn2,Plek,Bcl2a1b,Vcam1,Bcl2a1a,Col4a2,Plat,Thbs1,Mcm6 |
| 8.309e-03 | -4.79 | regulation of microtubule cytoskeleton organization | biological process | GO:0070507 | 198 | 23 | 20694 | 1406 |
Mid1,Trim36,Cenpj,Hspa1a,Tpx2,Dst,Mecp2,Met,Hspa1b,Plk2,Hsph1,Cdk5r1,Kat2b,Cav1,Tmem67,Dync1h1,Chmp4b,Agrn,Mark2,Gpsm2,Phldb1,Gda,Parp3 |
| 8.317e-03 | -4.79 | Signalling to ERKs | REACTOME pathways | R-MMU-187687 | 226 | 31 | 8608 | 757 |
Mapkapk2,Rapgef2,Rasgrp1,Psmb9,Psme1,Dusp5,Crkl,Psmb6,Dusp6,Psmb10,Ptk2,Met,Psmb8,Psmd10,Psme2,Psma6,Ksr1,Il2rg,Pdgfrb,Ppp2r1b,Jak2,Map2k1,Spred1,Kitl,Pdgfb,Ralgds,Angpt1,Psme2b,Src,Irs2,Ppp2r5a |
| 8.334e-03 | -4.79 | response to glucocorticoid | biological process | GO:0051384 | 81 | 12 | 20694 | 1406 |
Il6,Jak2,Ifnb1,Tnf,Fas,Nr3c1,Zfp36,Il10,Ddit4,Il1rn,Map2k1,Ass1 |
| 8.363e-03 | -4.78 | retina vasculature development in camera-type eye | biological process | GO:0061298 | 27 | 6 | 20694 | 1406 |
Pdgfb,Clic4,Hif1a,Slc4a7,Acvrl1,Pdgfrb |
| 8.363e-03 | -4.78 | cellular senescence | biological process | GO:0090398 | 27 | 6 | 20694 | 1406 |
Pml,Cdkn1a,Cav1,Map2k1,Sirt1,Smc5 |
| 8.363e-03 | -4.78 | labyrinthine layer morphogenesis | biological process | GO:0060713 | 27 | 6 | 20694 | 1406 |
Spint2,Vcam1,Socs3,Fzd5,Itga4,Il10 |
| 8.379e-03 | -4.78 | negative regulation of small molecule metabolic process | biological process | GO:0062014 | 91 | 13 | 20694 | 1406 |
Sirt1,Stat3,Plek,Ier3,Gfi1,Pid1,Trib3,Bmp2,Ddit4,Atp2b4,Il6,Nfkb1,Nupr1 |
| 8.412e-03 | -4.78 | AMIT_SERUM_RESPONSE_240_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_240_MCF10A | 53 | 10 | 15632 | 1249 |
Thbs1,Serpinb2,Pcdh7,Itga5,Ezr,Adrb2,Tlr2,Serpine1,Arhgef3,B4galt4 |
| 8.417e-03 | -4.78 | mesenchymal cell differentiation | biological process | GO:0048762 | 154 | 19 | 20694 | 1406 |
Kitl,Jag1,Cited2,Phactr4,Gja1,Htr2b,Edn1,Hif1a,Sema4c,Trip10,Sema4a,Plaur,Acvr1,Bmp2,Notch1,Sema3c,Nrp2,Ednrb,Acvrl1 |
| 8.454e-03 | -4.77 | morphogenesis of embryonic epithelium | biological process | GO:0016331 | 176 | 21 | 20694 | 1406 |
Hhex,Sdc4,Casp8,Mthfd1l,Sec24b,Lhx2,Ift57,Apaf1,Vasp,Fzd1,Casp3,Mthfr,Lmo4,Ptch1,Spint2,Sema4c,Hif1a,Vegfc,Tulp3,Phactr4,Cited2 |
| 8.463e-03 | -4.77 | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN | 179 | 24 | 15632 | 1249 |
Mgat1,Tmem184b,D16Ertd472e,Apobec3,Ppp1r14b,Fut8,Ctsc,Casp3,Rars,Cd38,Mvp,Cd14,Zbp1,Cnp,Cav1,Rcn1,Trib1,Sema4a,Ifi35,Casp7,Mtdh,Etnk1,Gfpt1,Cflar |
| 8.463e-03 | -4.77 | GSE17186_MEMORY_VS_NAIVE_BCELL_DN | MSigDB lists | GSE17186_MEMORY_VS_NAIVE_BCELL_DN | 179 | 24 | 15632 | 1249 |
Cebpd,Trim36,Lipe,B4galt4,Sla,Cd80,Slc25a25,Rbl1,Apaf1,Ddx60,Atf3,Rnf135,Kmo,Ltbp2,Arid4a,Atp6v1d,Serpinb2,Rgs1,Chd9,Znrf1,Vrk2,Acsl1,Adora2b,Rcan1 |
| 8.463e-03 | -4.77 | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_UP | MSigDB lists | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_UP | 179 | 24 | 15632 | 1249 |
Lrp8,Spred1,Ppfibp1,Ahr,Extl2,Sgk3,Acpp,Spsb1,Ehd1,Chst11,Cdyl2,Phactr4,Sema4a,Atp10a,C3,Cmklr1,Jak2,Rap2c,Daam1,Ahrr,Ccne1,Gja1,Ube2e2,Timeless |
| 8.463e-03 | -4.77 | GSE8621_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE8621_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN | 179 | 24 | 15632 | 1249 |
Rnf19a,Wdr59,Nmi,Sema3c,Hopx,Vps54,Sesn3,Epsti1,Slfn9,Spata5l1,Arid5b,Azi2,Cpeb4,Dyrk2,Stat1,Taf4b,Samd9l,Stat3,Slfn8,Ppp2r5a,Rhof,Bcl6,Rnf114,Il4ra |
| 8.463e-03 | -4.77 | GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN | 179 | 24 | 15632 | 1249 |
Cpeb4,Ust,Tnfsf10,Slfn9,Cmpk2,Hsd17b12,Ttc9c,Lcp2,Irf7,Slc2a6,Evl,Prdm1,Atp11a,Stat2,Papss2,Tnfrsf14,Rbl1,Plac8,Cst7,Homer1,Arid5a,Bcl6,Mgat1,Slfn8 |
| 8.463e-03 | -4.77 | GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP | MSigDB lists | GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP | 179 | 24 | 15632 | 1249 |
Ifit2,Gypc,Tpst1,Cited2,Pml,Nupr1,Col18a1,Cyth3,Hif1a,Ppm1l,Enpp4,Ankib1,Dach1,Hk1,Sesn3,Sik3,Ampd3,Cpeb4,St3gal1,Ptk2,Spire1,Osbpl3,Zcchc2,Prkar2b |
| 8.463e-03 | -4.77 | GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_UP | MSigDB lists | GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_UP | 179 | 24 | 15632 | 1249 |
Csrp1,P4ha2,Fam43a,Nlrc5,Plac8,Trip10,Fubp1,Cd40,Acpp,Tnfsf14,Cyfip1,Gbp9,Gbp4,Ikzf1,Spint2,Car13,S1pr2,Dram1,Il18,Pttg1,Usp18,Tspo,Sdc4,Gda |
| 8.463e-03 | -4.77 | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_UP | MSigDB lists | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_UP | 179 | 24 | 15632 | 1249 |
Map2k1,Arid4a,Slc4a7,Dusp6,Card6,Icosl,Dyrk2,Cd200,Smc5,Pkp4,Notch2,Chd9,Ldlr,Cd40,Rab32,Slc25a37,Parp8,Stap1,Peli1,Pttg1,Kmo,Bcor,Rras2,Traf5 |
| 8.463e-03 | -4.77 | GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_UP | MSigDB lists | GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_UP | 179 | 24 | 15632 | 1249 |
Hk1,Ccr1,Junb,Ppp1r15a,Cysltr2,Il12rb1,Itpkc,Il13ra1,Scyl2,Dram1,Casp7,Usp42,Thbs1,Nfkb2,Il1rn,Sqstm1,Phgdh,Mlkl,Stk40,Ap3b1,Ifrd1,Ppm1l,Traf5,Zfp319 |
| 8.463e-03 | -4.77 | GSE7852_TREG_VS_TCONV_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_DN | 179 | 24 | 15632 | 1249 |
Pde4b,Dusp6,Map4k4,Plekha2,Inpp5b,Rnf19a,Usp12,Dyrk2,Pim2,Mob3b,Sema4a,Orai2,Inpp1,Pik3r5,Itpr1,Otud1,Dse,Arid5a,Ikzf1,Setdb2,Slc30a4,Nxf1,St3gal6,Pde3b |
| 8.467e-03 | -4.77 | SIMBULAN_UV_RESPONSE_NORMAL_UP | MSigDB lists | SIMBULAN_UV_RESPONSE_NORMAL_UP | 6 | 3 | 15632 | 1249 |
Il6,Cxcl1,Cxcl2 |
| 8.467e-03 | -4.77 | GERHOLD_RESPONSE_TO_TZD_UP | MSigDB lists | GERHOLD_RESPONSE_TO_TZD_UP | 6 | 3 | 15632 | 1249 |
Ccnd1,Ccnd2,Casp8 |
| 8.467e-03 | -4.77 | FOURNIER_ACINAR_DEVELOPMENT_EARLY_DN | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_EARLY_DN | 6 | 3 | 15632 | 1249 |
Thbs1,Lrp8,Phlda1 |
| 8.468e-03 | -4.77 | GSE3720_UNSTIM_VS_LPS_STIM_VD2_GAMMADELTA_TCELL_UP | MSigDB lists | GSE3720_UNSTIM_VS_LPS_STIM_VD2_GAMMADELTA_TCELL_UP | 141 | 20 | 15632 | 1249 |
Plac8,Psmb8,Dusp6,Med21,Trim21,Rab21,Fchsd2,Psme2,Tnfsf8,Dgka,Magohb,Rcsd1,Traf1,Rtp4,Rras2,Znrf1,Batf,Ikbke,Pkp4,Samhd1 |
| 8.468e-03 | -4.77 | GSE4984_UNTREATED_VS_LPS_TREATED_DC_UP | MSigDB lists | GSE4984_UNTREATED_VS_LPS_TREATED_DC_UP | 141 | 20 | 15632 | 1249 |
Ccr3,Pdgfb,Nr3c1,Peli1,Taf4b,Lztfl1,Acvrl1,Morc3,Casp8,Sh3bgrl2,Clcf1,Mob3c,Tlr9,Lrch3,Parp3,Itpkc,Calcrl,Tulp3,Mppe1,Rab20 |
| 8.468e-03 | -4.77 | GSE3565_DUSP1_VS_WT_SPLENOCYTES_POST_LPS_INJECTION_UP | MSigDB lists | GSE3565_DUSP1_VS_WT_SPLENOCYTES_POST_LPS_INJECTION_UP | 141 | 20 | 15632 | 1249 |
Parp8,Srm,Treml2,Mdn1,Tlr1,Tnfsf8,Fchsd2,Myc,Traf1,Sell,Magohb,Etnk1,Pim2,Socs3,Tlr6,Rcl1,Atp11b,Adam19,Cldnd1,Ikbke |
| 8.479e-03 | -4.77 | GO_POSITIVE_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS | 11 | 4 | 15632 | 1249 |
Hdac1,Hif1a,Nr1h3,Edn1 |
| 8.479e-03 | -4.77 | SEMBA_FHIT_TARGETS_UP | MSigDB lists | SEMBA_FHIT_TARGETS_UP | 11 | 4 | 15632 | 1249 |
Oas1g,Col27a1,Oas1a,Sphk1 |
| 8.479e-03 | -4.77 | REACTOME_THE_NLRP3_INFLAMMASOME | MSigDB lists | REACTOME_THE_NLRP3_INFLAMMASOME | 11 | 4 | 15632 | 1249 |
Casp1,Txn1,Mefv,Nlrp3 |
| 8.479e-03 | -4.77 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_15 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_15 | 11 | 4 | 15632 | 1249 |
Hmga1,Pim1,Irf4,Dek |
| 8.479e-03 | -4.77 | GO_NEGATIVE_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION | 11 | 4 | 15632 | 1249 |
Ppp1r15a,Spred1,Spry2,Ddit4 |
| 8.479e-03 | -4.77 | REACTOME_P2Y_RECEPTORS | MSigDB lists | REACTOME_P2Y_RECEPTORS | 11 | 4 | 15632 | 1249 |
P2ry13,P2ry2,P2ry14,P2ry12 |
| 8.479e-03 | -4.77 | GO_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE | MSigDB lists | GO_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE | 11 | 4 | 15632 | 1249 |
Inhba,Asns,Notch1,Hmgcs1 |
| 8.479e-03 | -4.77 | GO_MICROGLIAL_CELL_ACTIVATION | MSigDB lists | GO_MICROGLIAL_CELL_ACTIVATION | 11 | 4 | 15632 | 1249 |
Cx3cl1,Jun,Tlr3,Cx3cr1 |
| 8.479e-03 | -4.77 | GO_I_KAPPAB_PHOSPHORYLATION | MSigDB lists | GO_I_KAPPAB_PHOSPHORYLATION | 11 | 4 | 15632 | 1249 |
Tlr2,Ikbke,Tlr9,Tlr3 |
| 8.479e-03 | -4.77 | GO_CYCLIN_DEPENDENT_PROTEIN_SERINE_THREONINE_KINASE_INHIBITOR_ACTIVITY | MSigDB lists | GO_CYCLIN_DEPENDENT_PROTEIN_SERINE_THREONINE_KINASE_INHIBITOR_ACTIVITY | 11 | 4 | 15632 | 1249 |
Cdkn2d,Casp3,Cdkn1a,Kat2b |
| 8.479e-03 | -4.77 | BIOCARTA_ASBCELL_PATHWAY | MSigDB lists | BIOCARTA_ASBCELL_PATHWAY | 11 | 4 | 15632 | 1249 |
Cd80,Fas,Cd40,Il10 |
| 8.479e-03 | -4.77 | MODULE_14 | MSigDB lists | MODULE_14 | 11 | 4 | 15632 | 1249 |
Tnfaip2,Jag1,Il18,Angpt1 |
| 8.479e-03 | -4.77 | GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | 11 | 4 | 15632 | 1249 |
Tnfsf4,Hlx,Bcl6,Il4ra |
| 8.488e-03 | -4.77 | PID_E2F_PATHWAY | MSigDB lists | PID_E2F_PATHWAY | 78 | 13 | 15632 | 1249 |
Plau,Apaf1,Cdkn1a,Rbl1,Casp7,Kat2b,Myc,Sirt1,Hdac1,Atm,Ccne1,Rbbp8,Serpine1 |
| 8.488e-03 | -4.77 | GO_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | 78 | 13 | 15632 | 1249 |
Cflar,Bmp2,Notch1,Daxx,Cxcl10,Il4ra,Edn1,Mmp14,Hdac1,Ehd1,Gdf15,Hopx,Tnfsf14 |
| 8.488e-03 | -4.77 | RASHI_RESPONSE_TO_IONIZING_RADIATION_6 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_6 | 78 | 13 | 15632 | 1249 |
Ikzf1,Fcgr2b,Slpi,Ccnj,Ifit1bl2,Ifit1bl1,S100a8,Ccl5,Psmb9,Gbp2,Fas,Hhex,Rhoh |
| 8.530e-03 | -4.76 | phosphotyrosine residue binding | molecular function | GO:0001784 | 43 | 8 | 20217 | 1400 |
Socs3,Crkl,Syk,Samsn1,Fgr,Acp2,Hck,Stap1 |
| 8.552e-03 | -4.76 | GSE4748_CYANOBACTERIUM_LPSLIKE_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN | MSigDB lists | GSE4748_CYANOBACTERIUM_LPSLIKE_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN | 160 | 22 | 15632 | 1249 |
Rnf24,Kcnj2,Arl4a,Herc3,Tuba4a,Fcgr4,Lcn2,Pdlim7,Slpi,Zfp36,Srxn1,Vasp,Inhba,Bst1,Mmp9,Dgkh,Rnf19b,Mafg,Mmp25,Sema4a,Il1rn,Igf2bp2 |
| 8.552e-03 | -4.76 | GO_RESPONSE_TO_CARBOHYDRATE | MSigDB lists | GO_RESPONSE_TO_CARBOHYDRATE | 160 | 22 | 15632 | 1249 |
Ptgs2,Lyn,Ptger4,Ldha,Pfkl,Il1b,Gfpt1,Thbs1,Ppp1r15a,Pdk3,Nfkb1,Gja1,Icam1,Hif1a,Calcrl,Irs2,Fas,Egr1,Me1,Plau,Mdm2,Casp3 |
| 8.558e-03 | -4.76 | cell redox homeostasis | biological process | GO:0045454 | 62 | 10 | 20694 | 1406 |
Prdx5,Prdx1,Ero1l,Il6,Glrx,Gclc,Gsr,Txn1,Sco1,Txnrd1 |
| 8.573e-03 | -4.76 | Platelet homeostasis | REACTOME pathways | R-MMU-418346 | 56 | 11 | 8608 | 757 |
Ptgir,Pla2g4a,Pde1b,Gna15,Itpr1,Fgr,Nos2,Pde5a,Lrp8,Atp2b4,Pde3b |
| 8.610e-03 | -4.75 | cytoskeletal protein binding | molecular function | GO:0008092 | 962 | 86 | 20217 | 1400 |
Mx2,Cnn2,Fcho2,Mid1,Hspa2,Vezt,Hap1,Mx1,Whamm,Mark2,Kif9,Kif3c,Ccdc88b,Antxr1,Marcks,Nfkb1,Rcsd1,Cep350,Cdk5r1,Pstpip2,Trim36,Hsph1,Prnp,Triobp,Mefv,Axl,Cyfip1,Evl,Spire1,Dst,Lrp8,Tor1aip1,Actb,Tmem67,Katna1,Tagln,Ezr,Pde4b,Gja1,Prkce,Lyn,Tpm4,Nod2,Ptk2,Kif5c,Sbds,Sipa1l1,Cenpe,Dbnl,Phf6,Phactr4,Hcls1,Rgs14,Cacybp,Myo1b,Cenpj,Dcp1a,Map4k4,Cnn3,Rab10,Ktn1,Micall2,Daam1,Tmsb10,Adora2a,Marcksl1,Nek6,Csrp1,Mtus1,Cacna1d,Ppp2r2a,Fmnl2,Nos2,Fabp3,Fscn1,Myo10,Daxx,S100a8,Vasp,Syne2,Palld,Diaph2,Tmod3,Bcl2l11,Pdlim7,Flnb |
| 8.647e-03 | -4.75 | HALLMARK_ESTROGEN_RESPONSE_EARLY | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_EARLY | 189 | 25 | 15632 | 1249 |
Egr3,Endod1,Asb13,Jak2,Igf1r,Ptges,Gja1,Lad1,P2ry2,Slc7a2,Slc7a5,Flnb,Rasgrp1,Papss2,Slc16a1,Aff1,Olfml3,Tsku,Fos,Slc2a1,Rbbp8,Tiparp,Cish,Myc,Ccnd1 |
| 8.647e-03 | -4.75 | HALLMARK_APICAL_JUNCTION | MSigDB lists | HALLMARK_APICAL_JUNCTION | 189 | 25 | 15632 | 1249 |
Traf1,Cx3cl1,Itga9,Icam1,Tgfbi,Mmp9,Ptk2,Evl,Nlgn2,Vcam1,Cd34,Actb,Fscn1,Layn,Zyx,Rhof,Cd274,Cd86,Syk,Ikbkg,Src,Cnn2,Vasp,Vcan,Akt3 |
| 8.647e-03 | -4.75 | GSE27786_BCELL_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_BCELL_VS_CD8_TCELL_UP | 189 | 25 | 15632 | 1249 |
Nfkbie,Ogfrl1,Gadd45g,Dbnl,Stard5,Fchsd2,Cyfip1,Hspa1a,Mgat1,Gadd45b,Relb,Pfkfb3,Il15,Ciita,Slc30a4,Leng9,Med13,Tor1aip1,Cnp,Slc4a7,Clic4,Ebi3,Mtmr14,Tmod3,Dtx2 |
| 8.658e-03 | -4.75 | TyrKc | smart domains | SM00219 | 81 | 14 | 9567 | 823 |
Jak2,Fgr,Lyn,Src,Met,Syk,Kdr,Pdgfrb,Hck,Axl,Ptk2,Tyk2,Igf1r,Flt1 |
| 8.680e-03 | -4.75 | MODULE_279 | MSigDB lists | MODULE_279 | 132 | 19 | 15632 | 1249 |
Crbn,Hspa1a,Timp1,Cish,Zeb1,Gclm,Cebpd,Dusp4,Ccng2,Snx2,Ifi35,Frmd4a,Cxcl10,Osgin2,Pfkfb3,Pilrb2,Pilrb1,Prkar2b,Sp110 |
| 8.692e-03 | -4.75 | transferase activity, transferring glycosyl groups | molecular function | GO:0016757 | 274 | 30 | 20217 | 1400 |
Tmtc2,Extl2,Plod3,Parp3,Parp12,Nampt,Pigv,B4galt4,Zc3hav1,St3gal3,Gbe1,Mgat1,Ext1,Parp14,Parp9,Upp1,Parp10,Dpy19l1,Gys1,St3gal6,B3gnt5,Gbgt1,Parp11,Pnp2,Tiparp,Gcnt2,Fut8,St3gal5,Parp8,St3gal1 |
| 8.735e-03 | -4.74 | - | gene3d domains | 3.60.20.10 | 22 | 6 | 8819 | 755 |
Psmb9,Asns,Psmb6,Psma6,Psmb8,Psmb10 |
| 8.779e-03 | -4.74 | - | gene3d domains | 3.30.500.10 | 50 | 10 | 8819 | 755 |
H2-M2,H2-T10,Procr,H2-Q6,H2-T24,H2-Q4,H2-T22,H2-Q7,Raet1e,H60b |
| 8.790e-03 | -4.73 | T cell proliferation | biological process | GO:0042098 | 44 | 8 | 20694 | 1406 |
Il15,Tnfsf4,Ripk2,Psmb10,Malt1,Itgal,Gja1,Ebi3 |
| 8.790e-03 | -4.73 | aminoglycan biosynthetic process | biological process | GO:0006023 | 44 | 8 | 20694 | 1406 |
Il1b,Chst11,Angpt1,Pdgfrb,Ext1,Dse,Extl2,B3gnt5 |
| 8.825e-03 | -4.73 | GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_UP | 170 | 23 | 15632 | 1249 |
Mapkapk2,Bcor,Atf3,Hif1a,Traf5,Tnfaip3,Tnfrsf14,Ddhd1,Axl,Myc,Peli1,Ly75,Dock10,Optn,Cd200,Itga5,Ebi3,Tnfsf4,Abcc1,Igsf9,Pdgfb,Icosl,Sirt1 |
| 8.825e-03 | -4.73 | LEF1_UP.V1_DN | MSigDB lists | LEF1_UP.V1_DN | 170 | 23 | 15632 | 1249 |
Ddx58,Usp18,Dmxl2,Papss2,Pdgfc,Mvp,Mdfic,Olr1,Oas3,Plac8,Il18,Herc6,Tlr3,Traf3ip2,Oas1g,Pf4,Cxcl1,Acsl5,Plod2,Stat4,Oas1a,Cnn3,Tnfsf15 |
| 8.825e-03 | -4.73 | GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 170 | 23 | 15632 | 1249 |
Atp13a1,Cish,D16Ertd472e,Arhgef3,Dhrs9,Mvp,Mark2,Hk3,Apaf1,Adar,Rnf34,Casp2,Zfp324,Snx2,Rnaset2a,Lnpep,Card6,Ttc9c,Fcgr4,Rnaset2b,Cd300lf,Jak2,Mppe1 |
| 8.828e-03 | -4.73 | Integrin_dom_sf | interpro domains | IPR032695 | 26 | 6 | 19984 | 1430 |
Itgb8,Itgav,Itga5,Itga4,Itga9,Itgal |
| 8.828e-03 | -4.73 | ABC1_TM_sf | interpro domains | IPR036640 | 26 | 6 | 19984 | 1430 |
Abcc5,Tap1,Abcb1a,Abcc4,Tap2,Abcc1 |
| 8.831e-03 | -4.73 | regulation of sensory perception of pain | biological process | GO:0051930 | 53 | 9 | 20694 | 1406 |
Edn1,Ednrb,Fcgr4,Ptafr,Slc9a1,Adrb2,Il1a,Acpp,Il10 |
| 8.831e-03 | -4.73 | astrocyte differentiation | biological process | GO:0048708 | 53 | 9 | 20694 | 1406 |
Fpr2,S100a8,Il1b,Adora2a,Notch1,Map2k1,Plpp3,Lif,Stat3 |
| 8.831e-03 | -4.73 | regulation of phospholipase activity | biological process | GO:0010517 | 53 | 9 | 20694 | 1406 |
Ccl5,Sele,Lpar1,Ptafr,Pdgfrb,Htr2b,Flt1,Htr2a,Arf4 |
| 8.831e-03 | -4.73 | regulation of mitochondrial membrane permeability | biological process | GO:0046902 | 53 | 9 | 20694 | 1406 |
Cnp,Pmaip1,Mul1,Bcl2l11,Stat3,Ier3,Hk2,Slc9a1,Bnip3 |
| 8.831e-03 | -4.73 | axonal transport | biological process | GO:0098930 | 53 | 9 | 20694 | 1406 |
Ap3b1,Rab21,Hap1,Uchl1,Hif1a,Dync1h1,Kif5c,Ap3m2,Dst |
| 8.850e-03 | -4.73 | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP | MSigDB lists | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP | 123 | 18 | 15632 | 1249 |
Arid5b,Lyn,Mcm6,Calcrl,Itga9,Pttg1,Cd200,Dusp5,Ch25h,Rbpms,Slc39a14,Pdpn,Pnp2,Isg20,Nos2,Rapgef5,Tuba4a,Gch1 |
| 8.850e-03 | -4.73 | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | 123 | 18 | 15632 | 1249 |
Il10,Psmd10,Rabgef1,Nfkbia,Txn1,Fzd1,Nfkbie,G3bp2,Nfkbib,Nlrp3,Dyrk2,Zc3h12a,Hmox1,Nfkbil1,Parp10,Mdfic,Keap1,Angpt1 |
| 8.863e-03 | -4.73 | GO_REGULATION_OF_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS | MSigDB lists | GO_REGULATION_OF_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS | 17 | 5 | 15632 | 1249 |
C3,Spn,Tnf,Il12b,Il10 |
| 8.863e-03 | -4.73 | GO_POSITIVE_REGULATION_OF_NATURAL_KILLER_CELL_ACTIVATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_NATURAL_KILLER_CELL_ACTIVATION | 17 | 5 | 15632 | 1249 |
Il15,Axl,Rasgrp1,Il12b,Il18 |
| 8.863e-03 | -4.73 | ZHENG_RESPONSE_TO_ARSENITE_DN | MSigDB lists | ZHENG_RESPONSE_TO_ARSENITE_DN | 17 | 5 | 15632 | 1249 |
Il1a,Mmp13,Cebpd,Cenpe,Myc |
| 8.863e-03 | -4.73 | GO_POSITIVE_REGULATION_OF_STEROL_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_STEROL_TRANSPORT | 17 | 5 | 15632 | 1249 |
Nr1h3,Ptch1,Sirt1,Lipg,Nfkbia |
| 8.863e-03 | -4.73 | CHEN_PDGF_TARGETS | MSigDB lists | CHEN_PDGF_TARGETS | 17 | 5 | 15632 | 1249 |
Gpd2,Arid5b,Tiparp,Klf2,Csrnp1 |
| 8.863e-03 | -4.73 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP | 17 | 5 | 15632 | 1249 |
Lrp8,Slc7a5,Ddit4,Stx11,Mthfd2 |
| 8.863e-03 | -4.73 | GO_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY | MSigDB lists | GO_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY | 17 | 5 | 15632 | 1249 |
Nfkbia,Ripk2,Prkce,Cd14,Tnip3 |
| 8.863e-03 | -4.73 | GO_CELLULAR_RESPONSE_TO_GROWTH_HORMONE_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_GROWTH_HORMONE_STIMULUS | 17 | 5 | 15632 | 1249 |
Lyn,Stat5a,Jak2,Ptk2,Stat3 |
| 8.863e-03 | -4.73 | KASLER_HDAC7_TARGETS_1_DN | MSigDB lists | KASLER_HDAC7_TARGETS_1_DN | 17 | 5 | 15632 | 1249 |
Trip10,Slc2a1,Sema4a,Hk2,C3 |
| 8.863e-03 | -4.73 | GO_MYELOID_DENDRITIC_CELL_DIFFERENTIATION | MSigDB lists | GO_MYELOID_DENDRITIC_CELL_DIFFERENTIATION | 17 | 5 | 15632 | 1249 |
Batf2,Irf4,Batf,Relb,Cd86 |
| 8.863e-03 | -4.73 | PID_NFKAPPAB_ATYPICAL_PATHWAY | MSigDB lists | PID_NFKAPPAB_ATYPICAL_PATHWAY | 17 | 5 | 15632 | 1249 |
Rel,Nfkb1,Syk,Src,Nfkbia |
| 8.863e-03 | -4.73 | GO_POSITIVE_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION | 17 | 5 | 15632 | 1249 |
Rap2c,Src,Pdgfb,Vegfc,Pdgfc |
| 8.863e-03 | -4.73 | GO_OVULATION | MSigDB lists | GO_OVULATION | 17 | 5 | 15632 | 1249 |
Sirt1,Ptgs2,Il1b,Il4ra,Pla2g4a |
| 8.863e-03 | -4.73 | GO_SIGNALING_PATTERN_RECOGNITION_RECEPTOR_ACTIVITY | MSigDB lists | GO_SIGNALING_PATTERN_RECOGNITION_RECEPTOR_ACTIVITY | 17 | 5 | 15632 | 1249 |
Cd14,Trim12c,Tlr2,Ptafr,Marco |
| 8.863e-03 | -4.73 | LI_ADIPOGENESIS_BY_ACTIVATED_PPARG | MSigDB lists | LI_ADIPOGENESIS_BY_ACTIVATED_PPARG | 17 | 5 | 15632 | 1249 |
Lipe,Nr1h3,Acsl1,Gpd2,Pcx |
| 8.863e-03 | -4.73 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | MSigDB lists | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | 17 | 5 | 15632 | 1249 |
Xrn1,Dcp1a,Dcp2,Mapkapk2,Zfp36 |
| 8.891e-03 | -4.72 | activin receptor complex | cellular component | GO:0048179 | 7 | 3 | 20747 | 1409 |
Acvrl1,Acvr1b,Acvr1 |
| 8.901e-03 | -4.72 | positive regulation of T-helper 2 cell cytokine production | biological process | GO:2000553 | 7 | 3 | 20694 | 1406 |
Il6,Rsad2,Nlrp3 |
| 8.901e-03 | -4.72 | regulation of extracellular matrix constituent secretion | biological process | GO:0003330 | 7 | 3 | 20694 | 1406 |
Tnfrsf1b,Notch1,Rgcc |
| 8.901e-03 | -4.72 | positive regulation of protein deubiquitination | biological process | GO:1903003 | 7 | 3 | 20694 | 1406 |
Tnip1,Tank,Zc3h12a |
| 8.901e-03 | -4.72 | negative regulation of cofactor metabolic process | biological process | GO:0051195 | 7 | 3 | 20694 | 1406 |
Stat3,Hp,Ptger4 |
| 8.901e-03 | -4.72 | cell proliferation involved in metanephros development | biological process | GO:0072203 | 7 | 3 | 20694 | 1406 |
Pdgfb,Ptch1,Pdgfrb |
| 8.901e-03 | -4.72 | positive regulation of toll-like receptor 3 signaling pathway | biological process | GO:0034141 | 7 | 3 | 20694 | 1406 |
Wdfy1,Peli1,Cav1 |
| 8.901e-03 | -4.72 | tumor necrosis factor superfamily cytokine production | biological process | GO:0071706 | 7 | 3 | 20694 | 1406 |
Tlr9,Azi2,Tlr2 |
| 8.901e-03 | -4.72 | response to herbicide | biological process | GO:0009635 | 7 | 3 | 20694 | 1406 |
Lcn2,Zc3h12a,Daxx |
| 8.901e-03 | -4.72 | response to nitrosative stress | biological process | GO:0051409 | 7 | 3 | 20694 | 1406 |
Gclc,Gclm,Atm |
| 8.901e-03 | -4.72 | negative regulation of microglial cell activation | biological process | GO:1903979 | 7 | 3 | 20694 | 1406 |
Cst7,Cx3cl1,Ldlr |
| 8.901e-03 | -4.72 | autophagic cell death | biological process | GO:0048102 | 7 | 3 | 20694 | 1406 |
Acp2,Cdkn2d,Bnip3 |
| 8.901e-03 | -4.72 | regulation of myeloid dendritic cell activation | biological process | GO:0030885 | 7 | 3 | 20694 | 1406 |
Klrk1,Il10,Clec4d |
| 8.901e-03 | -4.72 | negative regulation of antigen processing and presentation | biological process | GO:0002578 | 7 | 3 | 20694 | 1406 |
Tapbpl,Fgl2,Thbs1 |
| 8.901e-03 | -4.72 | regulation of isotype switching to IgE isotypes | biological process | GO:0048293 | 7 | 3 | 20694 | 1406 |
Bcl6,Tnfsf4,Clcf1 |
| 8.901e-03 | -4.72 | diapedesis | biological process | GO:0050904 | 7 | 3 | 20694 | 1406 |
Itga4,Crkl,Ccl5 |
| 8.901e-03 | -4.72 | reelin-mediated signaling pathway | biological process | GO:0038026 | 7 | 3 | 20694 | 1406 |
Lrp8,Stat5a,Crkl |
| 8.901e-03 | -4.72 | platelet-derived growth factor receptor-beta signaling pathway | biological process | GO:0035791 | 7 | 3 | 20694 | 1406 |
Pdgfb,Lox,Pdgfrb |
| 8.901e-03 | -4.72 | epithelial cell proliferation involved in salivary gland morphogenesis | biological process | GO:0060664 | 7 | 3 | 20694 | 1406 |
Il6,Pdgfb,Tnf |
| 8.901e-03 | -4.72 | gas homeostasis | biological process | GO:0033483 | 7 | 3 | 20694 | 1406 |
Hif1a,Cav1,Sod2 |
| 8.901e-03 | -4.72 | response to interleukin-12 | biological process | GO:0070671 | 7 | 3 | 20694 | 1406 |
Ripk2,Il12rb1,Jak2 |
| 8.901e-03 | -4.72 | negative regulation of p38MAPK cascade | biological process | GO:1903753 | 7 | 3 | 20694 | 1406 |
Ezr,Hsph1,Dusp1 |
| 8.901e-03 | -4.72 | prostaglandin transport | biological process | GO:0015732 | 7 | 3 | 20694 | 1406 |
Slco3a1,Abcc4,Nos2 |
| 8.901e-03 | -4.72 | positive regulation of mast cell chemotaxis | biological process | GO:0060754 | 7 | 3 | 20694 | 1406 |
Ccl5,Swap70,Vegfc |
| 8.901e-03 | -4.72 | regulation of apoptotic cell clearance | biological process | GO:2000425 | 7 | 3 | 20694 | 1406 |
Ccl2,Cd300lf,C3 |
| 8.901e-03 | -4.72 | pulmonary artery morphogenesis | biological process | GO:0061156 | 7 | 3 | 20694 | 1406 |
Jag1,Sec24b,Cited2 |
| 8.901e-03 | -4.72 | protein poly-ADP-ribosylation | biological process | GO:0070212 | 7 | 3 | 20694 | 1406 |
Parp14,Parp3,Parp10 |
| 8.901e-03 | -4.72 | positive regulation of natural killer cell proliferation | biological process | GO:0032819 | 7 | 3 | 20694 | 1406 |
Il15,Il18,Il12b |
| 8.901e-03 | -4.72 | negative regulation of hydrogen peroxide metabolic process | biological process | GO:0010727 | 7 | 3 | 20694 | 1406 |
Ptger4,Hp,Stat3 |
| 8.901e-03 | -4.72 | positive regulation of prostaglandin biosynthetic process | biological process | GO:0031394 | 7 | 3 | 20694 | 1406 |
Il1b,Ptgs2,Pla2g4a |
| 8.901e-03 | -4.72 | regulation of NK T cell differentiation | biological process | GO:0051136 | 7 | 3 | 20694 | 1406 |
Ap3b1,Ikzf1,Prdm1 |
| 8.901e-03 | -4.72 | regulation of dendritic cell apoptotic process | biological process | GO:2000668 | 7 | 3 | 20694 | 1406 |
Axl,Rapgef2,Lyn |
| 8.901e-03 | -4.72 | chemokine production | biological process | GO:0032602 | 7 | 3 | 20694 | 1406 |
Tnfsf4,Mcoln2,Nod2 |
| 8.901e-03 | -4.72 | hemoglobin biosynthetic process | biological process | GO:0042541 | 7 | 3 | 20694 | 1406 |
Hif1a,Lyn,Inhba |
| 8.901e-03 | -4.72 | paracrine signaling | biological process | GO:0038001 | 7 | 3 | 20694 | 1406 |
Pdgfb,Cd34,Cgas |
| 8.925e-03 | -4.72 | Signalling to RAS | REACTOME pathways | R-MMU-167044 | 218 | 30 | 8608 | 757 |
Psmb10,Psmb8,Ptk2,Met,Psmd10,Psma6,Psme2,Mapkapk2,Rapgef2,Psmb9,Rasgrp1,Dusp5,Psme1,Dusp6,Psmb6,Kitl,Spred1,Ralgds,Pdgfb,Psme2b,Angpt1,Src,Irs2,Ppp2r5a,Il2rg,Ksr1,Pdgfrb,Ppp2r1b,Map2k1,Jak2 |
| 8.934e-03 | -4.72 | MHC_I-like_Ag-recog | interpro domains | IPR011161 | 42 | 8 | 19984 | 1430 |
H2-M2,H2-T24,H2-T22,H2-T10,H2-Q7,H2-Q4,H2-Q6,Procr |
| 8.959e-03 | -4.72 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | 96 | 15 | 15632 | 1249 |
St3gal5,Sat1,Ass1,Tuba4a,Slc16a3,Rapgef5,Dock4,Igsf8,Timp1,Lad1,Sgk3,Etv5,Ell2,Il18,Adora2b |
| 8.959e-03 | -4.72 | MODULE_145 | MSigDB lists | MODULE_145 | 96 | 15 | 15632 | 1249 |
Rsad2,Spint2,Mecp2,Icosl,Irf8,Abcc5,Tap1,Hvcn1,Tnfaip2,Cmklr1,Il4ra,Rcsd1,Fgr,Kcna3,Cd200 |
| 8.959e-03 | -4.72 | GO_EXTRINSIC_COMPONENT_OF_CYTOPLASMIC_SIDE_OF_PLASMA_MEMBRANE | MSigDB lists | GO_EXTRINSIC_COMPONENT_OF_CYTOPLASMIC_SIDE_OF_PLASMA_MEMBRANE | 96 | 15 | 15632 | 1249 |
Gng12,Hck,Jak2,Rgs1,Gng11,Cyth3,Fgr,Lyn,Ptk2,Gng4,Errfi1,Tyk2,Gna15,Src,Syk |
| 8.965e-03 | -4.71 | YAGI_AML_SURVIVAL | MSigDB lists | YAGI_AML_SURVIVAL | 114 | 17 | 15632 | 1249 |
Tspo,Cd14,Prpf4,Gng12,Hmgcs1,Dmxl2,Phactr4,Vasp,Stx11,Bst1,Taf4b,Apobec3,Rab32,Nfkbia,Med21,Zyx,Traf2 |
| 8.979e-03 | -4.71 | GO_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE | MSigDB lists | GO_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE | 70 | 12 | 15632 | 1249 |
Il1b,Nlrp3,Ptgs2,C3,Cd55,Il6,Pla2g4a,Osm,Ednrb,Ccl5,Spn,Tnf |
| 8.979e-03 | -4.71 | GO_CELLULAR_GLUCOSE_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_GLUCOSE_HOMEOSTASIS | 70 | 12 | 15632 | 1249 |
Fas,Ptger4,Irs2,Hif1a,Icam1,Plau,Il1b,Hk3,Hk1,Pdk3,Hk2,Sirt1 |
| 8.993e-03 | -4.71 | regulation of DNA metabolic process | biological process | GO:0051052 | 363 | 37 | 20694 | 1406 |
Mecp2,Atm,Il6,Pdgfb,Dusp1,Parp9,Timeless,Dcp2,Apaf1,Prdm9,Acvrl1,Fbxo4,Src,Dach1,Cdkn1a,Pml,Smg7,Eya4,Tnfsf4,Igf1r,Cd40,Gja1,Fignl2,Radx,Ahr,Clcf1,Spire1,Dek,Myc,Dtx3l,Bcl6,Pdgfrb,Ier3,Sirt1,Ppp4r2,Parp3,Cgas |
| 8.994e-03 | -4.71 | regulation of double-strand break repair | biological process | GO:2000779 | 72 | 11 | 20694 | 1406 |
Pml,Parp3,Ppp4r2,Cgas,Dtx3l,Timeless,Radx,Parp9,Dek,Spire1,Fignl2 |
| 8.997e-03 | -4.71 | peptidyl-serine phosphorylation | biological process | GO:0018105 | 177 | 21 | 20694 | 1406 |
Mapkapk2,Mark2,Sgk3,Morc3,Akt3,Pdk3,Prkx,Tlk2,Plk2,Src,Dyrk2,Rictor,Cdk5r1,Hk1,Prkce,Ikbke,Pdgfb,Nek6,Syk,Vrk2,Atm |
| 9.007e-03 | -4.71 | REACTOME_GLYCOSAMINOGLYCAN_METABOLISM | MSigDB lists | REACTOME_GLYCOSAMINOGLYCAN_METABOLISM | 105 | 16 | 15632 | 1249 |
Ext1,Slc9a1,Vcan,Chst11,Sdc2,Abcc5,Agrn,B4galt4,Dse,Ust,Gpc1,Sdc4,St3gal3,St3gal1,St3gal6,Sdc1 |
| 9.007e-03 | -4.71 | DAZARD_RESPONSE_TO_UV_SCC_UP | MSigDB lists | DAZARD_RESPONSE_TO_UV_SCC_UP | 105 | 16 | 15632 | 1249 |
Fos,Cited2,Map2k1,Eif2ak2,Tnf,Cxcl2,Plscr1,Il6,Ptgs2,Atf3,Ube2e1,Il13ra1,Il1b,Pgk1,Cxcl1,Rras2 |
| 9.007e-03 | -4.71 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | 105 | 16 | 15632 | 1249 |
Tra2a,Peli1,Ampd3,Slpi,Slfn8,Nrp2,Dock4,Mtus1,Klf2,Slfn9,Cflar,Frmd4a,Itga9,Nupr1,Mmp9,Hp |
| 9.014e-03 | -4.71 | Axon guidance | REACTOME pathways | R-MMU-422475 | 436 | 53 | 8608 | 757 |
Psmd10,Cdk5r1,Vasp,Gpc1,Sdc2,Psmb10,Nck1,Itga5,Rnd1,Psmb9,Pik3cd,Nrp2,Src,Lyn,Itga9,Angpt1,Psme2b,Prnp,Spred1,Pdlim7,Ppp2r1b,Cacna1d,Sema4a,Cacnb3,Psme2,Psma6,Ptk2,Met,Psmb8,Psmb6,Dusp6,Psme1,Dusp5,Rasgrp1,Rapgef2,Irs2,Rhoc,Ppp2r5a,Evl,Pdgfb,Col4a2,Kitl,Ezr,Jak2,Itgav,Map2k1,Mmp9,Kdr,Pdgfrb,Stip1,Actb,Ksr1,Il2rg |
| 9.024e-03 | -4.71 | female gonad development | biological process | GO:0008585 | 102 | 14 | 20694 | 1406 |
Arid5b,Tiparp,Angpt1,Sirt1,Src,Pla2g4a,Atm,Kdr,Stat5a,Kitl,Inhba,Serpine1,Nos2,Ahr |
| 9.042e-03 | -4.71 | E4F1_Q6 | MSigDB lists | E4F1_Q6 | 249 | 31 | 15632 | 1249 |
Tle3,Slc25a25,Rbms2,Arg2,Slc39a13,Calcrl,S1pr2,Egr2,Nr3c1,Zmynd15,Rbbp8,Flrt3,Nr4a1,Dusp1,Slc25a37,Armcx6,Ppp2r2a,Pkp4,Arf4,Nr4a3,Trib1,Slc31a1,Gng4,Egr3,Maff,Leng9,Fosb,Gem,Ptch1,Ppp1r15a,Tor1aip1 |
| 9.048e-03 | -4.71 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_DN | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_DN | 180 | 24 | 15632 | 1249 |
Kif5c,Crkl,Smox,Prkx,Ralgds,Lrrc8c,Igf1r,Lad1,Adora2a,Slamf9,Vasn,Sell,Prnp,Tab2,Tmtc2,Sav1,Kif9,Relb,Armcx6,Birc2,Swap70,Fchsd2,B3gnt5,Phlpp1 |
| 9.048e-03 | -4.71 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_DN | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_DN | 180 | 24 | 15632 | 1249 |
Cers6,Gpr35,Ikzf1,Abcb1a,P2ry12,Rbl1,Hvcn1,1600014C10Rik,P2ry14,Gbe1,Aldh1b1,Cdkn2d,Evl,Casp2,Stoml1,Phlpp2,Isg20,Plod2,Slc12a9,Gng12,Chd9,Tnfsf10,Herc6,Etnk1 |
| 9.048e-03 | -4.71 | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP | 180 | 24 | 15632 | 1249 |
Sp140,Cenpe,Ezr,Rbbp8,Ccr3,Phgdh,Fut8,Dusp4,Egr1,Itga4,Tpx2,Pttg1,Cd38,Ccne1,Clic5,Abtb2,Itgal,Trip13,Timeless,Piezo1,Inpp5b,Mcm6,Trib1,Cldnd1 |
| 9.048e-03 | -4.71 | GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_UP | MSigDB lists | GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_UP | 180 | 24 | 15632 | 1249 |
Cacybp,Slamf9,Oas1a,Endod1,Stat1,Oas1g,Kif5c,Phyh,Arid5b,Jak2,Tnip1,Rcl1,Pkp4,Zhx2,Snn,Gadd45b,Sod2,Usp53,Ifi44,Aftph,Rsad2,Ddx60,Bcor,Prnp |
| 9.077e-03 | -4.70 | Ovarian tumor domain proteases | REACTOME pathways | R-MMU-5689896 | 28 | 7 | 8608 | 757 |
Tnfaip3,Tnip1,Nod1,Ripk2,Nod2,Ikbkg,Tnip3 |
| 9.106e-03 | -4.70 | P4Hc | smart domains | SM00702 | 16 | 5 | 9567 | 823 |
P4ha2,P4ha1,Plod2,Egln3,Plod3 |
| 9.108e-03 | -4.70 | regulatory RNA binding | molecular function | GO:0061980 | 35 | 7 | 20217 | 1400 |
Pnpt1,Tut7,Ago3,Zc3h12a,Zc3h7a,Tlr9,Mecp2 |
| 9.115e-03 | -4.70 | Type II diabetes mellitus | KEGG pathways | ko04930 | 48 | 10 | 7931 | 713 |
Socs1,Hk1,Pik3cd,Irs2,Socs3,Hk3,Cacna1d,Prkce,Hk2,Tnf |
| 9.115e-03 | -4.70 | Type II diabetes mellitus | KEGG pathways | mmu04930 | 48 | 10 | 7931 | 713 |
Cacna1d,Hk3,Socs3,Irs2,Pik3cd,Hk1,Socs1,Tnf,Hk2,Prkce |
| 9.139e-03 | -4.70 | RODRIGUES_NTN1_TARGETS_DN | MSigDB lists | RODRIGUES_NTN1_TARGETS_DN | 142 | 20 | 15632 | 1249 |
Ier3,Arid5b,Papss2,Gda,Rbms2,Fscn1,Klf2,Irf8,Ogfr,Rhof,Nr4a1,Dusp6,Tnfrsf1b,Arhgap26,Cnot4,Vasp,Met,Spen,Tnfsf15,Flnb |
| 9.146e-03 | -4.69 | serine/threonine protein kinase complex | cellular component | GO:1902554 | 82 | 12 | 20747 | 1409 |
Ccne1,Cdkn2d,Cdk5r1,Acvr1b,Ccnj,Cdkn1a,Acvrl1,Acvr1,Ccnd1,Ikbkg,Ccng2,Ccnd2 |
| 9.147e-03 | -4.69 | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN | MSigDB lists | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN | 38 | 8 | 15632 | 1249 |
Gbp2,Ppfibp1,Rbpms,H2-Aa,Sell,Dusp6,H2-Ab1,Hlx |
| 9.147e-03 | -4.69 | GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | MSigDB lists | GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | 38 | 8 | 15632 | 1249 |
Lyn,Serpinb9,Pik3cd,Nr4a3,Il6,Stxbp3,Trem1,Rasgrp1 |
| 9.147e-03 | -4.69 | GNF2_VAV1 | MSigDB lists | GNF2_VAV1 | 38 | 8 | 15632 | 1249 |
Hcls1,Phf11a,Phf11c,Sp110,Phf11b,Phf11d,Psmb10,Pik3cd |
| 9.147e-03 | -4.69 | GO_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | 38 | 8 | 15632 | 1249 |
Stap1,Plcl2,Ptpn2,Lyn,Prnp,Malt1,Ezr,Ptprj |
| 9.147e-03 | -4.69 | CHUNG_BLISTER_CYTOTOXICITY_DN | MSigDB lists | CHUNG_BLISTER_CYTOTOXICITY_DN | 38 | 8 | 15632 | 1249 |
Pdk3,Max,Sell,Kat2b,Gca,Irak3,Snn,Rap1gap2 |
| 9.147e-03 | -4.69 | ZHAN_MULTIPLE_MYELOMA_HP_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_HP_UP | 38 | 8 | 15632 | 1249 |
Fchsd2,Gng11,Tnfsf10,Ccrl2,Rsad2,Oas2,Scyl2,Ddx58 |
| 9.147e-03 | -4.69 | GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | 38 | 8 | 15632 | 1249 |
Tap1,Ifnb1,Serpinb9,Bcl6,H2-Q6,H2-Q4,Spn,H2-Q7 |
| 9.177e-03 | -4.69 | cellular component morphogenesis | biological process | GO:0032989 | 853 | 76 | 20694 | 1406 |
Nrp2,Sema3c,Lhx2,Map4k4,Src,Micall2,Lst1,Sema4a,Map2k1,Dock10,Scn1b,Dst,Cyfip1,Nes,Rilpl1,Lrp4,Vasp,Cflar,Gpc1,Tmod3,Csrp1,Palld,Pid1,Axl,Notch1,Dbnl,Flnb,Gja1,Itgav,Ptch1,Flrt3,Spint2,Klf7,Ahr,Nr4a3,Cdk5r1,Tlr2,Evl,Met,Pikfyve,Cnp,Sdc2,Stxbp1,Kif5c,Kdr,Egr2,Pdpn,Pnpt1,Snx2,Adora2a,Bcl6,Itga4,Plod3,Sec24b,Pdgfrb,Actb,Psmb10,Ptk2,Agrn,Clic5,Rac3,Nectin2,Antxr1,Clic4,Igf1r,Klf2,Tsku,Ext1,Ntng2,Triobp,Frmd6,Uchl1,Col18a1,Flrt2,Rab10,Lrp8 |
| 9.181e-03 | -4.69 | GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH1_UP | 161 | 22 | 15632 | 1249 |
Ly75,Nr3c1,Akt3,Rap1gap2,Syne2,Lztfl1,4932438A13Rik,Casp1,Abcc5,Crbn,Plac8,Cep350,Sik3,Rsbn1,Abcc4,Tnfrsf14,Itga5,Usp25,Dmxl2,Irs2,Il18,Trim13 |
| 9.181e-03 | -4.69 | GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_6H_DN | MSigDB lists | GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_6H_DN | 161 | 22 | 15632 | 1249 |
Jag1,Itgb8,Gclm,Ptpn2,Col11a2,Tor3a,Klf7,Cd38,Slamf7,Cxcl1,Serpinb9,Asb13,Arg2,Ptgs2,Slc43a3,Lpar1,Osgin2,Pml,Ebi3,Tlr3,Dram1,Abr |
| 9.190e-03 | -4.69 | ZF_RING_1 | prosite domains | PS00518 | 155 | 21 | 13278 | 1037 |
Pml,Trim56,Dtx3l,Trim13,Traf2,Trim21,Traf5,Rnf14,Bfar,Rnf31,Trim34a,Trim12c,Trim30a,Trim30d,Cop1,Mid1,Rnf114,Pcgf5,Rnf135,Trim36,Trim12a |
| 9.199e-03 | -4.69 | regulation of mitotic cell cycle phase transition | biological process | GO:1901990 | 257 | 28 | 20694 | 1406 |
Ube2e2,Hspa2,Ankrd17,Trip13,Rbl1,Ccnd1,Pbx1,Rgcc,Ier3,Psme1,Mdm2,Gpr132,Cenpe,Ccnd2,Psme2,Atm,Mecp2,Dcun1d3,Nek6,Pdpn,Plk3,Tmod3,Slfn1,Ccl12,Ccne1,Cdkn1a,Casp2,Pml |
| 9.212e-03 | -4.69 | GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 300 | 36 | 15632 | 1249 |
Smc5,Psmb6,Tmod3,Pim1,Cdkn1a,Atm,Psmb8,Cenpj,Plk2,Pid1,Psme2,Btg2,Gpr132,Casp2,Ube2e2,Pml,Nek6,Ube2e1,Psme1,Plk3,Psmb10,Plagl1,Pbx1,Tnks1bp1,Atp2b4,Cenpe,Dusp1,Ankrd17,Psmd10,Psmb9,Pdpn,Psma6,Hspa2,Mdm2,Ccnd1,Cnot4 |
| 9.226e-03 | -4.69 | GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_UP | MSigDB lists | GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_UP | 190 | 25 | 15632 | 1249 |
Rims3,Gbp7,Cd86,Nrp2,Socs3,Rcn1,Znrf1,Lrrc8c,Vegfc,Plac8,Rgs14,Swap70,Dusp8,B3gnt5,Phlpp1,Ddx60,Mxd1,Rtp4,Ppm1l,Dtx3l,Kat2b,Prnp,1600014C10Rik,Cd34,Trp53i11 |
| 9.226e-03 | -4.69 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_UP | 190 | 25 | 15632 | 1249 |
Egln3,Hk2,Ksr1,Sap30,Abcc1,Dusp16,Rsbn1,Mafg,Ier3,Cox18,Adora2b,Ak4,Slc31a1,Mdm2,Rab9,Slc2a1,Tpst1,Cst7,P4ha2,Prpf38a,Jmjd6,Hif1a,Lrp8,Slc30a4,Prdm1 |
| 9.235e-03 | -4.68 | endocardium development | biological process | GO:0003157 | 13 | 4 | 20694 | 1406 |
Angpt1,Notch1,Kdr,Acvr1 |
| 9.235e-03 | -4.68 | negative regulation of protein autophosphorylation | biological process | GO:0031953 | 13 | 4 | 20694 | 1406 |
Jun,Cav1,Errfi1,Mvp |
| 9.235e-03 | -4.68 | positive regulation of odontogenesis | biological process | GO:0042482 | 13 | 4 | 20694 | 1406 |
Csf1,Edn1,Bmp2,Cd34 |
| 9.235e-03 | -4.68 | positive regulation of heat generation | biological process | GO:0031652 | 13 | 4 | 20694 | 1406 |
Ccl5,Ptgs2,Tnf,Il1b |
| 9.235e-03 | -4.68 | susceptibility to natural killer cell mediated cytotoxicity | biological process | GO:0042271 | 13 | 4 | 20694 | 1406 |
Nectin2,H60b,Raet1e,Pvr |
| 9.235e-03 | -4.68 | cellular response to granulocyte macrophage colony-stimulating factor stimulus | biological process | GO:0097011 | 13 | 4 | 20694 | 1406 |
Stat5a,Pde1b,Zfp36,Etv3 |
| 9.235e-03 | -4.68 | branching involved in labyrinthine layer morphogenesis | biological process | GO:0060670 | 13 | 4 | 20694 | 1406 |
Fzd5,Socs3,Spint2,Il10 |
| 9.235e-03 | -4.68 | hemoglobin metabolic process | biological process | GO:0020027 | 13 | 4 | 20694 | 1406 |
Hif1a,Lyn,Inhba,Tet2 |
| 9.235e-03 | -4.68 | positive regulation of type I interferon-mediated signaling pathway | biological process | GO:0060340 | 13 | 4 | 20694 | 1406 |
Ikbke,Irf7,Nlrc5,Zbp1 |
| 9.235e-03 | -4.68 | regulation of NLRP3 inflammasome complex assembly | biological process | GO:1900225 | 13 | 4 | 20694 | 1406 |
Tlr6,Trim30a,Eif2ak2,Mefv |
| 9.235e-03 | -4.68 | response to increased oxygen levels | biological process | GO:0036296 | 13 | 4 | 20694 | 1406 |
Nox1,Fas,Cav1,Sod2 |
| 9.235e-03 | -4.68 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | biological process | GO:0061418 | 13 | 4 | 20694 | 1406 |
Cited2,Notch1,Hif1a,Egr1 |
| 9.235e-03 | -4.68 | cytoplasmic sequestering of transcription factor | biological process | GO:0042994 | 13 | 4 | 20694 | 1406 |
Nfkbib,Nfkbia,Keap1,Psmd10 |
| 9.235e-03 | -4.68 | regulation of cholesterol storage | biological process | GO:0010885 | 13 | 4 | 20694 | 1406 |
Ttc39b,Ehd1,Msr1,Nr1h3 |
| 9.235e-03 | -4.68 | positive regulation of urine volume | biological process | GO:0035810 | 13 | 4 | 20694 | 1406 |
Adora2a,Ednrb,Edn1,Ptger4 |
| 9.235e-03 | -4.68 | negative regulation of glycolytic process | biological process | GO:0045820 | 13 | 4 | 20694 | 1406 |
Ddit4,Nupr1,Ier3,Stat3 |
| 9.235e-03 | -4.68 | regulation of anion channel activity | biological process | GO:0010359 | 13 | 4 | 20694 | 1406 |
Prnp,Ptafr,Hk1,Abcb1a |
| 9.290e-03 | -4.68 | His_PPase_superfam | interpro domains | IPR029033 | 19 | 5 | 19984 | 1430 |
Acpp,Minpp1,Ubash3b,Pfkfb3,Acp2 |
| 9.290e-03 | -4.68 | Proteasome_sua/b | interpro domains | IPR001353 | 19 | 5 | 19984 | 1430 |
Psmb8,Psmb6,Psmb9,Psma6,Psmb10 |
| 9.290e-03 | -4.68 | Int_alpha_beta-p | interpro domains | IPR013519 | 19 | 5 | 19984 | 1430 |
Itga9,Itgal,Itgav,Itga5,Itga4 |
| 9.290e-03 | -4.68 | Integrin_alpha_N | interpro domains | IPR028994 | 19 | 5 | 19984 | 1430 |
Itgav,Itga5,Itga4,Itgal,Itga9 |
| 9.305e-03 | -4.68 | organelle organization | biological process | GO:0006996 | 3031 | 237 | 20694 | 1406 |
Cd34,Prdm9,Plk2,Plek,Fbxo4,Chd9,Ddhd1,Cep350,Gem,Kdm4a,G3bp2,Sap30,Cflar,Mcm9,Vasp,Ttc39c,Cnn2,Palld,Tet2,Pmaip1,Pttg1,Hmga2,Pim3,Diaph2,Acp2,Hk2,Rhof,Dnaaf3,Ift57,Nck1,Fnbp1l,H3f3b,Irgm1,Gpr35,Denr,Katna1,Sik3,Plaat3,Setdb2,Arhgap26,Atp6v1d,Bcl6,Bnip3,Pdlim7,Tor1aip2,Mark2,Ccdc88b,Rnd1,Kdm6b,Daam1,Kmt5a,Brd2,Tmem67,Mtfr2,Srgn,Rab10,Nr3c1,Cox17,Sass6,Stat3,Bcl2l11,Src,Ggct,Snx10,Map2k1,Sec24a,Hcls1,Pdgfb,Dst,Marcks,Ube2e1,Abcc4,Optn,Swap70,Mcm6,Akt3,Rgs14,Hat1,Bcor,Jak2,Rictor,Tnfaip3,Hmgn3,Dek,Evl,Slc9a1,Slamf8,Ccl2,Ezr,Sco1,Phactr4,Mecp2,Arid4a,Cenpj,Ascc3,Aebp2,Pnpt1,Hopx,Ap3b1,Rhou,Vps54,Myc,Rsbn1,Pdgfrb,Ptk2,Rab3ip,Rac3,Kdm5b,S1pr2,Antxr1,Hspa2,Tor1aip1,Rhoq,Stx6,Ntng2,Sipa1l1,Triobp,Spry2,Cdyl,Coa5,Whamm,Tpm4,Marf1,Ddx4,Atm,Abr,Syne2,Cox18,Csrp1,Sirt1,Ier3,Gpsm2,Cnn3,Hhex,Rab32,Sqstm1,Dbnl,Tagln,Samd9l,F11r,Cav1,Spire1,Parp11,Pstpip2,Noct,Ikzf1,Rab20,Kif9,Pml,Brwd3,Zyx,Pim2,Eya4,Ccl12,Bcorl1,Tpx2,Stxbp1,Pcgf5,Trim36,Jun,Sod2,Daxx,Tnf,Plk3,Tuba4a,Ift22,Rpgrip1l,Fscn1,Sec24b,Actb,Parp3,Gclc,Rbl1,Nlgn2,Dync1h1,Dr1,Phip,Fignl2,Kat2b,Jmjd6,Slc16a1,Casp4,Myo1b,Cdc42ep2,Jarid2,Micall2,Ccne1,Hap1,Rrs1,Stx11,Smg7,Tlk2,Rilpl1,Mthfr,Mcmbp,Irgm2,Znfx1,Mul1,Tmod3,Smc5,Tomm70a,Mdn1,Pid1,Trip10,Rhoh,Chmp4b,Vcpip1,Flnb,Znrf1,Mx1,Top3a,Mx2,Sbds,Rnd3,Hdac1,Fmnl2,Adgrg6,Asf1a,Cnp,Intu,Hspa1a,Lnpk,Cenpe,Ehd1,Gclm,Dtx3l,Irf4,Ep400,Nectin2,Rhoc,Trip13,Xrn1,Frmd6,Tmsb10,Carmil1,Rubcnl,Nsd3 |
| 9.308e-03 | -4.68 | NCAM signaling for neurite out-growth | REACTOME pathways | R-MMU-375165 | 237 | 32 | 8608 | 757 |
Cacnb3,Il2rg,Ksr1,Pdgfrb,Cacna1d,Ppp2r1b,Map2k1,Jak2,Kitl,Col4a2,Spred1,Pdgfb,Prnp,Psme2b,Angpt1,Src,Ppp2r5a,Irs2,Rapgef2,Psmb9,Rasgrp1,Dusp5,Psme1,Dusp6,Psmb6,Psmb10,Psmb8,Ptk2,Met,Psmd10,Psma6,Psme2 |
| 9.361e-03 | -4.67 | TARS (threonyl-tRNA synthetase) | protein interactions | 6897 | 2 | 2 | 7778 | 753 |
Max,Brwd3 |
| 9.361e-03 | -4.67 | Trim40 (tripartite motif-containing 40) | protein interactions | 195359 | 2 | 2 | 7778 | 753 |
Ifih1,Ddx58 |
| 9.361e-03 | -4.67 | PTPN23 (protein tyrosine phosphatase non-receptor type 23) | protein interactions | 25930 | 2 | 2 | 7778 | 753 |
Cenpe,Chmp4b |
| 9.361e-03 | -4.67 | POLB (DNA polymerase beta) | protein interactions | 5423 | 2 | 2 | 7778 | 753 |
Junb,Ktn1 |
| 9.361e-03 | -4.67 | Gbp2 (guanylate binding protein 2) | protein interactions | 14469 | 2 | 2 | 7778 | 753 |
Iigp1,Sqstm1 |
| 9.361e-03 | -4.67 | Angptl8 (angiopoietin-like 8) | protein interactions | 624219 | 2 | 2 | 7778 | 753 |
Sqstm1,Ikbkg |
| 9.361e-03 | -4.67 | Taf3 (TATA-box binding protein associated factor 3) | protein interactions | 209361 | 2 | 2 | 7778 | 753 |
Hmga2,Hmga1 |
| 9.361e-03 | -4.67 | CENPE (centromere protein E) | protein interactions | 1062 | 2 | 2 | 7778 | 753 |
Max,Cenpe |
| 9.361e-03 | -4.67 | Itga2 (integrin alpha 2) | protein interactions | 16398 | 2 | 2 | 7778 | 753 |
Lyn,Src |
| 9.361e-03 | -4.67 | ERBB2 (erb-b2 receptor tyrosine kinase 2) | protein interactions | 2064 | 2 | 2 | 7778 | 753 |
Errfi1,Tor1aip1 |
| 9.361e-03 | -4.67 | ORF75 (ORF75) | protein interactions | 1461076 | 2 | 2 | 7778 | 753 |
Traf2,Traf1 |
| 9.361e-03 | -4.67 | WDR3 (WD repeat domain 3) | protein interactions | 10885 | 2 | 2 | 7778 | 753 |
Rrbp1,Brwd3 |
| 9.361e-03 | -4.67 | Rhbdd3 (rhomboid domain containing 3) | protein interactions | 279766 | 2 | 2 | 7778 | 753 |
Tnfaip3,Ikbkg |
| 9.361e-03 | -4.67 | Ccr2 (chemokine (C-C motif) receptor 2) | protein interactions | 12772 | 2 | 2 | 7778 | 753 |
Ccl7,Ccl2 |
| 9.361e-03 | -4.67 | PRMT6 (protein arginine methyltransferase 6) | protein interactions | 55170 | 2 | 2 | 7778 | 753 |
Hmga1,Hmga2 |
| 9.361e-03 | -4.67 | ACKR2 (atypical chemokine receptor 2) | protein interactions | 1238 | 2 | 2 | 7778 | 753 |
Ccl3,Ccl2 |
| 9.361e-03 | -4.67 | Plcb4 (phospholipase C, beta 4) | protein interactions | 18798 | 2 | 2 | 7778 | 753 |
Itpr1,Homer1 |
| 9.361e-03 | -4.67 | ATP6V1E1 (ATPase H+ transporting V1 subunit E1) | protein interactions | 529 | 2 | 2 | 7778 | 753 |
Chmp4b,Rmdn3 |
| 9.361e-03 | -4.67 | EIF2S2 (eukaryotic translation initiation factor 2 subunit beta) | protein interactions | 8894 | 2 | 2 | 7778 | 753 |
Rrbp1,Ksr1 |
| 9.361e-03 | -4.67 | Snapc5 (small nuclear RNA activating complex, polypeptide 5) | protein interactions | 330959 | 2 | 2 | 7778 | 753 |
Fos,Jun |
| 9.361e-03 | -4.67 | S100b (S100 protein, beta polypeptide, neural) | protein interactions | 20203 | 2 | 2 | 7778 | 753 |
Stat1,Cacybp |
| 9.361e-03 | -4.67 | TNFRSF8 (TNF receptor superfamily member 8) | protein interactions | 943 | 2 | 2 | 7778 | 753 |
Traf1,Traf2 |
| 9.361e-03 | -4.67 | S1pr1 (sphingosine-1-phosphate receptor 1) | protein interactions | 13609 | 2 | 2 | 7778 | 753 |
Src,Jak2 |
| 9.361e-03 | -4.67 | MC159L (MC159L) | protein interactions | 1487017 | 2 | 2 | 7778 | 753 |
Traf1,Traf2 |
| 9.361e-03 | -4.67 | KAT2A (lysine acetyltransferase 2A) | protein interactions | 2648 | 2 | 2 | 7778 | 753 |
Notch1,Myc |
| 9.361e-03 | -4.67 | RPS27L (ribosomal protein S27 like) | protein interactions | 51065 | 2 | 2 | 7778 | 753 |
Ktn1,Rrbp1 |
| 9.361e-03 | -4.67 | Efs (embryonal Fyn-associated substrate) | protein interactions | 13644 | 2 | 2 | 7778 | 753 |
Src,Ptk2 |
| 9.363e-03 | -4.67 | regulation of cellular response to growth factor stimulus | biological process | GO:0090287 | 269 | 29 | 20694 | 1406 |
Spry2,Notch2,Cav1,Chst11,Pmepa1,Vasn,Fam20c,Sirt1,Zeb1,Notch1,Hhex,Cyfip1,Vegfc,Pdgfb,Cited2,Kdr,Bambi,Flt1,Htra1,Hif1a,Tcf4,Cflar,Fzd1,Gpc1,Lox,Fam72a,Thbs1,Acvrl1,Angpt1 |
| 9.373e-03 | -4.67 | PID_CD8_TCR_PATHWAY | MSigDB lists | PID_CD8_TCR_PATHWAY | 62 | 11 | 15632 | 1249 |
Cd80,Map3k8,H2-Q7,Malt1,Rasgrp1,Prkce,Cd86,Lcp2,H2-Q6,H2-Q4,Ikbkg |
| 9.386e-03 | -4.67 | transforming growth factor beta receptor activity, type I | molecular function | GO:0005025 | 7 | 3 | 20217 | 1400 |
Acvrl1,Acvr1b,Acvr1 |
| 9.386e-03 | -4.67 | G protein-coupled adenosine receptor activity | molecular function | GO:0001609 | 7 | 3 | 20217 | 1400 |
P2ry12,Adora2a,Adora2b |
| 9.386e-03 | -4.67 | type 1 angiotensin receptor binding | molecular function | GO:0031702 | 7 | 3 | 20217 | 1400 |
Jak2,Ednrb,Tyk2 |
| 9.386e-03 | -4.67 | vascular endothelial growth factor-activated receptor activity | molecular function | GO:0005021 | 7 | 3 | 20217 | 1400 |
Kdr,Flt1,Nrp2 |
| 9.386e-03 | -4.67 | CXCR chemokine receptor binding | molecular function | GO:0045236 | 7 | 3 | 20217 | 1400 |
Cx3cl1,Cxcl10,Pf4 |
| 9.433e-03 | -4.66 | regulation of T-helper 17 cell differentiation | biological process | GO:2000319 | 20 | 5 | 20694 | 1406 |
Malt1,Zc3h12a,Nlrp3,Nfkbid,Nfkbiz |
| 9.433e-03 | -4.66 | decidualization | biological process | GO:0046697 | 20 | 5 | 20694 | 1406 |
Ptgs2,Pla2g4a,Junb,Lif,Cited2 |
| 9.433e-03 | -4.66 | regulation of toll-like receptor 4 signaling pathway | biological process | GO:0034143 | 20 | 5 | 20694 | 1406 |
Acod1,Peli1,Nr1h3,Wdfy1,Lyn |
| 9.433e-03 | -4.66 | G1 DNA damage checkpoint | biological process | GO:0044783 | 20 | 5 | 20694 | 1406 |
Ccnd1,Pml,Casp2,Mdm2,Cdkn1a |
| 9.433e-03 | -4.66 | positive regulation of cell adhesion mediated by integrin | biological process | GO:0033630 | 20 | 5 | 20694 | 1406 |
Piezo1,Rac3,Ccl5,Syk,P2ry12 |
| 9.433e-03 | -4.66 | negative regulation of natural killer cell mediated immunity | biological process | GO:0002716 | 20 | 5 | 20694 | 1406 |
Tap1,Tap2,Clec2d,Serpinb9,Lgals9 |
| 9.433e-03 | -4.66 | pyroptosis | biological process | GO:0070269 | 20 | 5 | 20694 | 1406 |
Casp1,Casp4,Nlrc4,Gsdmd,Aim2 |
| 9.433e-03 | -4.66 | negative regulation of nucleotide metabolic process | biological process | GO:0045980 | 20 | 5 | 20694 | 1406 |
Ddit4,Ier3,Nupr1,Stat3,Pid1 |
| 9.438e-03 | -4.66 | MODULE_235 | MSigDB lists | MODULE_235 | 79 | 13 | 15632 | 1249 |
Gclm,Ube2l6,Ldlr,Alas1,Gclc,Hmgcs1,Ube2e1,Ass1,Gch1,Asns,Phyh,Odc1,Tpst1 |
| 9.450e-03 | -4.66 | GSE3982_BASOPHIL_VS_TH2_UP | MSigDB lists | GSE3982_BASOPHIL_VS_TH2_UP | 171 | 23 | 15632 | 1249 |
Casp4,Flnb,Pstpip2,Tdrd7,Bst1,Dram1,Hp,Map2k4,Osgin2,Actb,Plekhf2,Parp8,Bcl6,Dse,Rhoq,Ppp2r5a,Trim12c,Slco3a1,P2ry14,St3gal6,Plagl1,Ddx58,Pilra |
| 9.467e-03 | -4.66 | WANG_MLL_TARGETS | MSigDB lists | WANG_MLL_TARGETS | 270 | 33 | 15632 | 1249 |
Htr2a,Cd14,Gda,Angpt1,Ppm1l,Kcnj2,Parp14,Mmp14,Cish,Dusp2,Il6,Arhgap26,Stat5a,Plac8,Clmp,Apobec3,Cxcl1,Il1rn,Adam19,Vegfc,Ptges,Hcar2,Egr3,Fndc3a,Tgfbi,Adora2b,Arid5b,Fabp7,Mmp13,Smpdl3b,Dgka,Plek,Slc7a2 |
| 9.493e-03 | -4.66 | GO_ION_HOMEOSTASIS | MSigDB lists | GO_ION_HOMEOSTASIS | 543 | 59 | 15632 | 1249 |
Pml,Slc30a4,Fabp3,Slc39a13,Hif1a,Cutc,Lipg,Sgk3,Cd38,Slc25a37,Cd40,Swap70,Itpr1,Slc39a4,Cp,Atp13a1,Hmox1,Slc31a1,Cd55,Grina,Clic4,Htr2b,Il1b,Ccl5,Gja1,Slc7a8,Ccr1,Slc4a7,Slc31a2,Atp6v1d,Slc30a1,Prnp,Tmtc2,Htr2a,Atp2b4,Ccl12,Myc,Ccl2,Prkce,Edn1,Ccr3,Kcnj2,Nox1,Mafg,Rab20,Cacnb3,Lpar1,Jak2,Xcr1,Ednrb,S100a8,Lcn2,P2ry2,Gna15,Cav1,Sco1,Slc9a1,Sirt1,Slc39a14 |
| 9.509e-03 | -4.66 | male gonad development | biological process | GO:0008584 | 113 | 15 | 20694 | 1406 |
Gja1,Kdr,Arid4a,Cited2,Fndc3a,Crkl,Nupr1,Ccnd1,Icam1,Inhba,Bcl2l11,H3f3b,Arid5b,Insl6,Hmga2 |
| 9.513e-03 | -4.66 | BOCHKIS_FOXA2_TARGETS | MSigDB lists | BOCHKIS_FOXA2_TARGETS | 394 | 45 | 15632 | 1249 |
Ube2l6,Junb,Cdc42ep4,Kdm6b,Crkl,Pcgf5,Slc31a1,Mafk,Fgl2,C1ra,Cish,Itpr1,Zswim4,Mapkbp1,Gys1,1600014C10Rik,Stat2,Psmb10,Isg15,Psme1,Mxd1,C1rl,Plod2,Clcn7,Cd82,Cd300lf,Ldlr,Acsl1,Mafg,Lyn,Ptk2,Itpkc,Bnip3,Gpr35,Stard5,Il6,Klf3,Fam43a,Slc25a25,Kif9,Zbtb5,Prdx1,Fbxo4,Trim13,Arrdc4 |
| 9.527e-03 | -4.65 | GO_CARBOHYDRATE_BINDING | MSigDB lists | GO_CARBOHYDRATE_BINDING | 220 | 28 | 15632 | 1249 |
Sell,Cd34,Gys1,Clec4e,Hk3,Olr1,P4ha2,Gypc,Plod3,Cd302,Ly75,Vcan,Sele,Clec5a,Phyh,Clec4d,Siglece,Gfpt1,Pfkl,Clec4n,P4ha1,Hk1,Lgals9,Layn,Plod2,Egln3,Cd69,Hk2 |
| 9.539e-03 | -4.65 | Detoxification of Reactive Oxygen Species | REACTOME pathways | R-MMU-3299685 | 35 | 8 | 8608 | 757 |
Sod2,Txnrd1,Prdx1,Cycs,Txn1,Ero1l,Prdx5,Gsr |
| 9.551e-03 | -4.65 | Proteasome | pfam domains | PF00227 | 19 | 5 | 18711 | 1348 |
Psmb6,Psmb10,Psmb8,Psma6,Psmb9 |
| 9.570e-03 | -4.65 | cellular response to ionizing radiation | biological process | GO:0071479 | 63 | 10 | 20694 | 1406 |
Tlk2,Egr1,Cdkn1a,Ccnd2,Sirt1,Fbxo4,Tank,Mdm2,Atm,Tnks1bp1 |
| 9.572e-03 | -4.65 | NFAT_Q4_01 | MSigDB lists | NFAT_Q4_01 | 240 | 30 | 15632 | 1249 |
Ext1,Usp12,Nfkbid,Ppp2r3a,Jarid2,Mier3,Map4k4,Ccl5,Ppm1k,Plod2,Mitd1,Tagap,Stip1,Zhx2,Nfil3,Ptges,Gfi1,Phf6,Ier3,Nr4a3,Zfp800,Fos,Zbtb5,Sla,Pde3b,Rgs3,Plagl2,Prdm1,Prrg4,Icam1 |
| 9.575e-03 | -4.65 | GO_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION | MSigDB lists | GO_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION | 46 | 9 | 15632 | 1249 |
Clcf1,Il6,Il10,Traf2,Il4ra,Cd40,Bcl6,Tnfsf4,Tnf |
| 9.575e-03 | -4.65 | GO_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS | 46 | 9 | 15632 | 1249 |
Il1b,Jak2,Edn1,Il6,Ptgs2,Klf2,Icam1,Tnf,Ass1 |
| 9.575e-03 | -4.65 | NADLER_OBESITY_DN | MSigDB lists | NADLER_OBESITY_DN | 46 | 9 | 15632 | 1249 |
Asns,Gpd2,Gbe1,Hp,Ppa1,Pcx,Gsta3,Rbms2,Gng11 |
| 9.575e-03 | -4.65 | GO_POSITIVE_REGULATION_OF_GLIOGENESIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_GLIOGENESIS | 46 | 9 | 15632 | 1249 |
Lyn,Lif,Notch1,Etv5,Il1b,Clcf1,Csf1,Tspo,Bmp2 |
| 9.575e-03 | -4.65 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | MSigDB lists | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | 46 | 9 | 15632 | 1249 |
Fcgr1,Psme2,Psma6,Psmb6,Psme1,Psmb8,Psmb10,Psmb9,Psmd10 |
| 9.590e-03 | -4.65 | 7tm_1 | pfam domains | PF00001 | 299 | 33 | 18711 | 1348 |
Ednrb,Ccr1,Ccrl2,Gpr141,Hcar2,Prokr1,Gpr85,Gpr132,Ptger4,Fpr2,Ptafr,Htr2a,S1pr2,Cysltr2,Xcr1,Ptgir,Cx3cr1,Fpr1,Htr2b,P2ry12,Gpr84,Adrb2,Ccr3,Gpr35,Cmklr1,Gpr18,Lpar1,P2ry13,Gpr68,Adora2b,P2ry2,P2ry14,Adora2a |
| 9.603e-03 | -4.65 | AGCATTA_MIR155 | MSigDB lists | AGCATTA_MIR155 | 124 | 18 | 15632 | 1249 |
Ell2,Socs1,Gpr85,Hif1a,Tab2,Sla,Ikbke,Sgk3,Myo10,Psip1,N4bp1,Hivep2,Ptpn2,Carhsp1,Arl5b,Bcorl1,Mecp2,G3bp2 |
| 9.604e-03 | -4.65 | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | MSigDB lists | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | 54 | 10 | 15632 | 1249 |
Ass1,Col18a1,Ppp1r14b,Il4ra,Irs2,Tmeff1,Inpp1,Met,Prkar2b,Tnfaip3 |
| 9.604e-03 | -4.65 | GO_REGULATION_OF_VIRAL_TRANSCRIPTION | MSigDB lists | GO_REGULATION_OF_VIRAL_TRANSCRIPTION | 54 | 10 | 15632 | 1249 |
Jun,Trim13,Ccl5,Mdfic,Hdac1,Notch1,Ccl4,Polr2g,Trim14,Trim21 |
| 9.604e-03 | -4.65 | GGTGAAG_MIR412 | MSigDB lists | GGTGAAG_MIR412 | 54 | 10 | 15632 | 1249 |
Slc16a3,Bcl6,Irf7,Cdk5r1,Hif1a,Ccdc88b,Armc8,Fmnl2,Clcn5,Pkp4 |
| 9.604e-03 | -4.65 | GO_REGULATION_OF_MONOOXYGENASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_MONOOXYGENASE_ACTIVITY | 54 | 10 | 15632 | 1249 |
Tnf,Gch1,Nfkb1,Hif1a,Cav1,Nod1,Atp2b4,Gfi1,Il1b,Htr2b |
| 9.604e-03 | -4.65 | ZHENG_GLIOBLASTOMA_PLASTICITY_DN | MSigDB lists | ZHENG_GLIOBLASTOMA_PLASTICITY_DN | 54 | 10 | 15632 | 1249 |
Plagl1,Cav1,Lpar1,Fosb,Ddhd1,Itga5,Bcl2l11,Ppfibp2,Rhou,Zfp36 |
| 9.620e-03 | -4.64 | protein localization to nucleus | biological process | GO:0034504 | 167 | 20 | 20694 | 1406 |
Tor1aip1,Syk,Kpna3,Phip,Syne2,Adar,Fam53c,Mdm2,Gbp2,Nfkbia,Tor1aip2,Stat3,Morc3,Cdkn1a,Pml,Pikfyve,Ranbp2,Txn1,Rrs1,Hhex |
| 9.620e-03 | -4.64 | cellular modified amino acid metabolic process | biological process | GO:0006575 | 167 | 20 | 20694 | 1406 |
Ero1l,P4ha2,Mthfr,Gsta3,Egln3,Ptges,Slc7a11,Sod2,Gsr,Mthfd2,Plod3,Gclm,Plscr1,P4ha1,Mthfd1l,Plod2,Dio2,Ass1,Gclc,Gch1 |
| 9.639e-03 | -4.64 | cellular response to fatty acid | biological process | GO:0071398 | 36 | 7 | 20694 | 1406 |
Ptger4,Zc3h12a,Pid1,Tnfsf4,Prkce,Pdk3,Ldlr |
| 9.639e-03 | -4.64 | 'de novo' protein folding | biological process | GO:0006458 | 36 | 7 | 20694 | 1406 |
Cd74,Hspa2,Ero1l,Hsph1,Hspa1b,Hspa1a,Dnajb4 |
| 9.639e-03 | -4.64 | cellular modified amino acid biosynthetic process | biological process | GO:0042398 | 36 | 7 | 20694 | 1406 |
Plod2,Gclc,Gch1,Plod3,Gclm,Plscr1,Mthfd1l |
| 9.639e-03 | -4.64 | regulation of humoral immune response | biological process | GO:0002920 | 36 | 7 | 20694 | 1406 |
C3,Nod2,Cd55,Tnf,Il1b,Fcgr2b,Acod1 |
| 9.639e-03 | -4.64 | response to axon injury | biological process | GO:0048678 | 36 | 7 | 20694 | 1406 |
Jun,P2ry12,Sod2,Map2k1,Tnc,Jak2,Flrt3 |
| 9.666e-03 | -4.64 | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | 181 | 24 | 15632 | 1249 |
Coa5,Slco3a1,Tmem176b,Klf7,Tmem184b,Axl,Il4i1,Carhsp1,Rnf24,St7,Endod1,Dyrk2,Fam162a,Snn,Cdkn1a,Fscn1,Clic4,Plk2,Mcm9,Pde4b,Rnf31,Cd69,Vasp,Rap1gap2 |
| 9.666e-03 | -4.64 | GSE3982_DC_VS_TH2_UP | MSigDB lists | GSE3982_DC_VS_TH2_UP | 181 | 24 | 15632 | 1249 |
Slc15a3,Rab9,Nfkbie,Nqo1,Rgs14,Pilra,Cd83,Slc48a1,Hk3,Ccl22,Slco3a1,Nlrp3,H2-Aa,Rtn2,Bst1,Slc31a2,Ppp1r15a,Fzd5,Clcn7,Cdkn1a,Ptk2,Slamf8,Tgfbi,Tlr2 |
| 9.666e-03 | -4.64 | GO_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | 181 | 24 | 15632 | 1249 |
Atm,Btg2,Casp2,Egln3,Cpeb4,Hmox1,Nr4a3,Map2k4,Clcf1,Jak2,Axl,Ccl12,Sod2,Bcl2l11,Jun,Casp3,Gclm,Mecp2,Nqo1,Stxbp1,Hif1a,Cdk5r1,Gclc,Angpt1 |
| 9.666e-03 | -4.64 | GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_UP | MSigDB lists | GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_UP | 181 | 24 | 15632 | 1249 |
Nfil3,Ldha,Serpinb9,Map2k4,Xaf1,Mmd,Myadm,Lgals9,Pml,Lif,Tpx2,Rtp4,Fgr,Plagl1,Carhsp1,Aftph,Irf4,Dhx58,Mlkl,Optn,Vcan,Arhgap26,Trmt1l,Tmem184b |
| 9.666e-03 | -4.64 | GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_UP | MSigDB lists | GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_UP | 181 | 24 | 15632 | 1249 |
Tiparp,Hmga1,Hspa1a,Apobec3,Stat5a,Stk40,Casp3,Sertad3,Ciapin1,Marcksl1,Rnd3,Sdc4,Traf5,Pim3,Jarid2,Cdyl,Cxcl2,Tbc1d13,Fzd1,Rnf19a,Mmd,Fam53c,Serpinb2,Rbms1 |
| 9.666e-03 | -4.64 | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_DN | MSigDB lists | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_DN | 181 | 24 | 15632 | 1249 |
Mmp9,Rcan1,Ppp2r1b,Cxcl1,Frmd6,Htr2b,Dio2,Gja1,Jarid2,Atp6v1d,Htra1,Tmem176a,Dgka,Prnp,Cd83,Bcl2l11,Tagln,Cnn2,Spsb1,Jun,Slc44a1,Nat2,Myc,Cxcl14 |
| 9.734e-03 | -4.63 | Lectin_C | pfam domains | PF00059 | 117 | 16 | 18711 | 1348 |
Cd69,Clec4n,Cd302,Klra2,Clec5a,Sele,Clec4d,Clec4a1,Sell,Klrk1,Layn,Olr1,Vcan,Clec2d,Ly75,Clec4e |
| 9.790e-03 | -4.63 | GO_REGULATION_OF_SENSORY_PERCEPTION | MSigDB lists | GO_REGULATION_OF_SENSORY_PERCEPTION | 31 | 7 | 15632 | 1249 |
Acpp,Il10,Adrb2,Ptafr,Ednrb,Edn1,Slc9a1 |
| 9.790e-03 | -4.63 | MODULE_131 | MSigDB lists | MODULE_131 | 31 | 7 | 15632 | 1249 |
Plat,Plscr1,Plau,F10,Adora2a,Plaur,Serpine1 |
| 9.790e-03 | -4.63 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_WS | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_WS | 31 | 7 | 15632 | 1249 |
Sgcb,Trp53i11,H2-Aa,Itgb8,Cept1,Glrx,Syk |
| 9.790e-03 | -4.63 | GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | 31 | 7 | 15632 | 1249 |
Ptpn2,Il1b,Socs1,Ncoa5,Pid1,Socs3,Cish |
| 9.790e-03 | -4.63 | GO_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL | MSigDB lists | GO_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL | 31 | 7 | 15632 | 1249 |
Pml,Trim12c,Trim13,Trim26,Trim21,Pcx,Chmp4b |
| 9.790e-03 | -4.63 | DORN_ADENOVIRUS_INFECTION_12HR_DN | MSigDB lists | DORN_ADENOVIRUS_INFECTION_12HR_DN | 31 | 7 | 15632 | 1249 |
Ccnd1,Cd83,Myc,Il6,Ier3,Nfkbia,Txnrd1 |
| 9.790e-03 | -4.63 | chr20q12 | MSigDB lists | chr20q12 | 31 | 7 | 15632 | 1249 |
Cd40,Mmp9,Slc13a3,Src,Ncoa5,Slpi,Sdc4 |
| 9.790e-03 | -4.63 | SIMBULAN_UV_RESPONSE_NORMAL_DN | MSigDB lists | SIMBULAN_UV_RESPONSE_NORMAL_DN | 31 | 7 | 15632 | 1249 |
Rbpms,Rbms1,Thbs1,Phlda1,Myc,Adrb2,Gadd45b |
| 9.790e-03 | -4.63 | GO_HEART_VALVE_DEVELOPMENT | MSigDB lists | GO_HEART_VALVE_DEVELOPMENT | 31 | 7 | 15632 | 1249 |
Notch1,Acvr1,Mdm2,Jag1,Bmp2,Notch2,Prdm1 |
| 9.790e-03 | -4.63 | DORSEY_GAB2_TARGETS | MSigDB lists | DORSEY_GAB2_TARGETS | 31 | 7 | 15632 | 1249 |
Dusp5,Serpine1,Gng11,Thbs1,Cd69,Ccrl2,Acvr1 |
| 9.798e-03 | -4.63 | Chronic myeloid leukemia | KEGG pathways | mmu05220 | 71 | 13 | 7931 | 713 |
Hdac1,Pik3cd,Map2k1,Myc,Cdkn1a,Ikbkg,Nfkbia,Ccnd1,Crkl,Nfkb1,Akt3,Mdm2,Stat5a |
| 9.798e-03 | -4.63 | Chronic myeloid leukemia | KEGG pathways | ko05220 | 71 | 13 | 7931 | 713 |
Cdkn1a,Hdac1,Pik3cd,Myc,Map2k1,Ikbkg,Nfkbia,Ccnd1,Crkl,Nfkb1,Stat5a,Akt3,Mdm2 |
| 9.810e-03 | -4.62 | polyol metabolic process | biological process | GO:0019751 | 103 | 14 | 20694 | 1406 |
Gk,Itpkc,Plcl2,Grk3,Degs2,Asah2,Gch1,Tpi1,Ptafr,Inpp1,Mecp2,Sphk1,Plpp1,Inpp5b |
| 9.810e-03 | -4.62 | sensory perception of pain | biological process | GO:0019233 | 103 | 14 | 20694 | 1406 |
Tnf,Ptgs2,P2ry2,Uchl1,Edn1,Nlgn2,Mecp2,Il1rn,Il12b,Ednrb,Il18,Ccl2,Cacnb3,Htr2a |
| 9.835e-03 | -4.62 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | MSigDB lists | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | 191 | 25 | 15632 | 1249 |
Psmb10,Dtx3l,Socs1,Ube2e1,Psme1,Ube2f,Fbxo4,Rnf34,Psmb9,Psmd10,Trim36,Spsb1,Psma6,Asb13,Psmb6,Socs3,Keap1,Ubr4,Lnpep,Psmb8,Uba7,Ube2e2,Psme2,Trim21,Ube2l6 |
| 9.838e-03 | -4.62 | LABBE_TGFB1_TARGETS_UP | MSigDB lists | LABBE_TGFB1_TARGETS_UP | 97 | 15 | 15632 | 1249 |
Sat1,Pdgfb,Slc9a1,Jag1,Gadd45g,Junb,Ass1,Cited2,Tcf4,Serpine1,Actb,Gpc1,Nupr1,Ptgs2,Lox |
| 9.846e-03 | -4.62 | GO_FORMATION_OF_PRIMARY_GERM_LAYER | MSigDB lists | GO_FORMATION_OF_PRIMARY_GERM_LAYER | 106 | 16 | 15632 | 1249 |
Col4a2,Nr4a3,Mmp9,Itga5,Dusp5,Itga4,Kdm6b,Dusp4,Inhba,Acvr1,Mmp14,Dusp2,Ets2,Itgav,Txnrd1,Dusp1 |
| 9.848e-03 | -4.62 | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_UP | MSigDB lists | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_UP | 162 | 22 | 15632 | 1249 |
Stap1,Fchsd2,Irf4,Mdn1,Sp140,Tcf4,Tspan3,Traf5,Rras2,Rhoh,Phlpp2,Cd69,Syne2,Rasgrp1,Asns,Adam19,Zhx2,Tcea1,Pim2,Il2rg,Arid5b,Odc1 |
| 9.852e-03 | -4.62 | GSE45365_NK_CELL_VS_CD8_TCELL_UP | MSigDB lists | GSE45365_NK_CELL_VS_CD8_TCELL_UP | 143 | 20 | 15632 | 1249 |
Fmnl2,Nfil3,Cflar,Aida,Ptprj,Ripk2,Zscan29,Oas2,Syne2,Carhsp1,Slpi,Ppp4r2,B4galt4,Gna15,Cyfip1,Serp1,Arid4a,Ddhd1,Card6,Pik3r5 |
| 9.852e-03 | -4.62 | LEE_NEURAL_CREST_STEM_CELL_UP | MSigDB lists | LEE_NEURAL_CREST_STEM_CELL_UP | 143 | 20 | 15632 | 1249 |
Ifi203,Cebpd,Phlda1,Ifi208,Ifi211,Nrp2,Ifi205,Hmga1,Ifi209,Mndal,Sema3c,Gypc,Ifi213,Ifi207,Serpinb9,St7,Ifi214,Ifi204,Tgfbi,Itga4 |
| 9.852e-03 | -4.62 | GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP | MSigDB lists | GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP | 143 | 20 | 15632 | 1249 |
Il4i1,Slc9a1,Isg20,Parp12,Mdm2,Ccrl2,Nfkbid,Gch1,Abtb2,Eif2ak2,Slc31a2,Txn1,Samsn1,Cd274,Ldlr,Slamf7,Clcf1,Parp10,Max,Xkr8 |
| 9.856e-03 | -4.62 | response to ionizing radiation | biological process | GO:0010212 | 124 | 16 | 20694 | 1406 |
Egr1,Sod2,Ccnd2,Atm,Dcun1d3,Tlk2,Cdkn1a,Cop1,Pmaip1,Pml,Fbxo4,Sirt1,Tank,Mdm2,Myc,Tnks1bp1 |
| 9.860e-03 | -4.62 | mouse chr5 F|5 60.64 cM | chromosome location | mouse chr5 F|5 60.64 cM | 8 | 3 | 24173 | 1464 |
Oas2,Oas3,Oas1b |
| 9.860e-03 | -4.62 | mouse chr14|14 A2 | chromosome location | mouse chr14|14 A2 | 8 | 3 | 24173 | 1464 |
Ube2e1,Nkiras1,Ube2e2 |
| 9.870e-03 | -4.62 | phosphate ion binding | molecular function | GO:0042301 | 13 | 4 | 20217 | 1400 |
Gng12,Pnp2,Mthfd2,Stat5a |
| 9.889e-03 | -4.62 | GO_CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY | MSigDB lists | GO_CYCLIC_NUCLEOTIDE_PHOSPHODIESTERASE_ACTIVITY | 24 | 6 | 15632 | 1249 |
Pde7b,Pde5a,Cnp,Pde1b,Pde3b,Pde4b |
| 9.889e-03 | -4.62 | MODULE_73 | MSigDB lists | MODULE_73 | 24 | 6 | 15632 | 1249 |
Tlr2,Il2rg,Il4ra,Il15ra,Tlr1,Myd88 |
| 9.889e-03 | -4.62 | GO_POSITIVE_REGULATION_OF_TISSUE_REMODELING | MSigDB lists | GO_POSITIVE_REGULATION_OF_TISSUE_REMODELING | 24 | 6 | 15632 | 1249 |
Syk,Pml,Il15,Ptger4,Il12b,Il18 |
| 9.889e-03 | -4.62 | VALK_AML_CLUSTER_2 | MSigDB lists | VALK_AML_CLUSTER_2 | 24 | 6 | 15632 | 1249 |
Pim1,Jag1,Pde3b,Map4k4,Pla2g4a,Ezr |
| 9.889e-03 | -4.62 | GO_POSITIVE_REGULATION_OF_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_PHOSPHATASE_ACTIVITY | 24 | 6 | 15632 | 1249 |
Bmp2,Jak2,Plek,Pdgfrb,Ripk3,Ppp1r15a |
| 9.889e-03 | -4.62 | BRACHAT_RESPONSE_TO_METHOTREXATE_DN | MSigDB lists | BRACHAT_RESPONSE_TO_METHOTREXATE_DN | 24 | 6 | 15632 | 1249 |
Pdk3,Hmgcs1,Stat5a,Eno1,Ak4,Higd1a |
| 9.889e-03 | -4.62 | GENTLES_LEUKEMIC_STEM_CELL_UP | MSigDB lists | GENTLES_LEUKEMIC_STEM_CELL_UP | 24 | 6 | 15632 | 1249 |
Slc37a3,Rbpms,Cd34,Hopx,Icam1,Birc3 |
| 9.889e-03 | -4.62 | GO_POSITIVE_REGULATION_OF_MONOOXYGENASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_MONOOXYGENASE_ACTIVITY | 24 | 6 | 15632 | 1249 |
Tnf,Nod1,Gch1,Hif1a,Il1b,Htr2b |
| 9.889e-03 | -4.62 | GO_REGULATION_OF_THYMOCYTE_AGGREGATION | MSigDB lists | GO_REGULATION_OF_THYMOCYTE_AGGREGATION | 24 | 6 | 15632 | 1249 |
Nfkbid,Rasgrp1,Il1b,Zeb1,Ptpn2,Egr3 |
| 9.889e-03 | -4.62 | PID_NECTIN_PATHWAY | MSigDB lists | PID_NECTIN_PATHWAY | 24 | 6 | 15632 | 1249 |
Src,Ptk2,Pdgfb,Itgav,F11r,Pdgfrb |
| 9.889e-03 | -4.62 | GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 24 | 6 | 15632 | 1249 |
Il1b,Vegfc,Hif1a,Itga5,Hhex,Flt1 |
| 9.914e-03 | -4.61 | T cell receptor signaling pathway | KEGG pathways | mmu04660 | 103 | 17 | 7931 | 713 |
Map3k8,Akt3,Fos,Nfkb1,Nfkbie,Jun,Rasgrp1,Tnf,Nfkbib,Malt1,Lcp2,Ikbkg,Nfkbia,Nck1,Il10,Pik3cd,Map2k1 |
| 9.914e-03 | -4.61 | T cell receptor signaling pathway | KEGG pathways | ko04660 | 103 | 17 | 7931 | 713 |
Nfkb1,Jun,Nfkbie,Map3k8,Akt3,Fos,Il10,Pik3cd,Map2k1,Ikbkg,Nfkbia,Nck1,Rasgrp1,Tnf,Nfkbib,Malt1,Lcp2 |
| 9.927e-03 | -4.61 | IL-6-type cytokine receptor ligand interactions | REACTOME pathways | R-MMU-6788467 | 22 | 6 | 8608 | 757 |
Jak2,Lif,Osm,Il27,Clcf1,Ebi3 |
| 9.942e-03 | -4.61 | protein kinase inhibitor activity | molecular function | GO:0004860 | 53 | 9 | 20217 | 1400 |
Trib1,Trib3,Spred1,Casp3,Cdkn2d,Cdkn1a,Prkar2b,Nck1,Kat2b |
| 9.958e-03 | -4.61 | regulation of lipase activity | biological process | GO:0060191 | 73 | 11 | 20694 | 1406 |
Nr1h3,Ccl5,Rhoc,Sele,Lpar1,Ptafr,Htr2b,Pdgfrb,Flt1,Arf4,Htr2a |
| 9.965e-03 | -4.61 | lipid binding | molecular function | GO:0008289 | 739 | 68 | 20217 | 1400 |
Ptch1,Rapgef2,Cgas,Gramd1a,Plekhf2,Fnbp1l,S100a8,Trip10,Snx10,Dgka,Mitd1,Pla2g4a,Pla2g7,Apol9b,Lyn,Traf2,Rnf34,Tlr2,Plekha5,Dennd1b,Aida,Fzd5,Tlr1,Plekhn1,Psd4,C3,Lpar1,Cyth3,Tulp3,Fcho2,Cd14,Stard5,Fchsd2,Myo1b,Itpr1,Tspo,Plek,Hspa2,Arhgap26,Adap2,Mark2,Sell,Wdfy1,Kcnj2,Nr3c1,F10,Tlr6,Sphk1,Rubcnl,Zcchc2,Psd,Sgk3,Rasgrp1,Gsdmd,Jag1,Fabp7,Stard7,Plekha2,Snx2,Ptafr,Axl,Osbpl3,Plekha4,Cd55,Apba1,Cd300lf,Fabp3,Thbs1 |
| 9.975e-03 | -4.61 | regulation of hormone metabolic process | biological process | GO:0032350 | 54 | 9 | 20694 | 1406 |
Igf1r,Nr3c1,Hif1a,Gfi1,Nfkb1,Il1b,Bmp2,Egr1,Tnf |
| 9.975e-03 | -4.61 | positive regulation of stem cell proliferation | biological process | GO:2000648 | 54 | 9 | 20694 | 1406 |
Cxcl1,Cx3cr1,Kitl,Hmga2,Notch1,Taf4b,Cx3cl1,Vegfc,Hif1a |
| 9.975e-03 | -4.61 | regulation of epidermal cell differentiation | biological process | GO:0045604 | 54 | 9 | 20694 | 1406 |
Errfi1,Zfp36,Ptch1,Mafg,Mycl,Keap1,Notch1,Maff,Klf7 |
| 9.975e-03 | -4.61 | protein K48-linked ubiquitination | biological process | GO:0070936 | 54 | 9 | 20694 | 1406 |
Peli1,Rnf34,Ube2e2,Bfar,Znrf1,Dtx3l,Ube2e1,Rffl,Tnfaip3 |
| 9.975e-03 | -4.61 | Role of phospholipids in phagocytosis | REACTOME pathways | R-MMU-2029485 | 16 | 5 | 8608 | 757 |
Fcgr2b,Syk,Prkce,Fcgr4,Fcgr1 |
| 9.975e-03 | -4.61 | Nitric oxide stimulates guanylate cyclase | REACTOME pathways | R-MMU-392154 | 16 | 5 | 8608 | 757 |
Pde1b,Itpr1,Pde3b,Pde5a,Nos2 |
| 9.975e-03 | -4.61 | Regulation of TLR by endogenous ligand | REACTOME pathways | R-MMU-5686938 | 16 | 5 | 8608 | 757 |
Tlr1,Tlr6,Tlr2,S100a8,Cd14 |
| 9.975e-03 | -4.61 | Inflammasomes | REACTOME pathways | R-MMU-622312 | 16 | 5 | 8608 | 757 |
Aim2,Nlrp3,Casp1,Txn1,Mefv |
| 9.975e-03 | -4.61 | RAF-independent MAPK1/3 activation | REACTOME pathways | R-MMU-112409 | 16 | 5 | 8608 | 757 |
Dusp5,Jak2,Il6,Map2k1,Dusp6 |
| 1.004e-02 | -4.60 | AAGGGAT_MIR188 | MSigDB lists | AAGGGAT_MIR188 | 71 | 12 | 15632 | 1249 |
Kpna3,Crkl,Il13ra1,Zfp281,Bcl9,Rap2c,Kitl,H3f3b,Rictor,Spred1,Igf2bp2,Snn |
| 1.004e-02 | -4.60 | KEGG_MELANOMA | MSigDB lists | KEGG_MELANOMA | 71 | 12 | 15632 | 1249 |
Ccnd1,Igf1r,Pdgfc,Mdm2,Cdkn1a,Met,Pdgfb,Akt3,Pdgfrb,Map2k1,Pik3cd,Pik3r5 |
| 1.004e-02 | -4.60 | GO_CELLULAR_RESPONSE_TO_KETONE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_KETONE | 71 | 12 | 15632 | 1249 |
Tnfsf4,Ptger4,Errfi1,Ifnb1,Il6,Prkce,Klf2,Src,Klf6,Ass1,Ccl5,Ccl12 |
| 1.004e-02 | -4.60 | positive regulation of coagulation | biological process | GO:0050820 | 28 | 6 | 20694 | 1406 |
Thbs1,Plek,Serpine1,Ptprj,Pdpn,Enpp4 |
| 1.005e-02 | -4.60 | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | 211 | 27 | 15632 | 1249 |
Plod2,Rrs1,Mthfd1l,Isg20,Slc7a5,Phlda1,Flnb,Mcm6,Asb13,Usp31,Endod1,Smox,Egr3,Ptges,Jak2,Cd82,Rbbp8,Tiparp,Myc,Hif1a,Atp11a,Mcm10,Lrp8,Olfml3,Rbl1,Sgk3,Slc16a1 |
| 1.007e-02 | -4.60 | regulation of calcium ion import | biological process | GO:0090279 | 45 | 8 | 20694 | 1406 |
Homer1,Prnp,Pdgfrb,Pdgfb,Slc30a1,Adrb2,Ccl12,Serpine1 |
| 1.007e-02 | -4.60 | negative regulation of cellular response to insulin stimulus | biological process | GO:1900077 | 45 | 8 | 20694 | 1406 |
Nck1,Cish,Socs3,Ptpn2,Pid1,Ncoa5,Il1b,Socs1 |
| 1.007e-02 | -4.60 | glomerulus development | biological process | GO:0032835 | 45 | 8 | 20694 | 1406 |
Egr1,Ahr,Jag1,Notch1,Notch2,Pdgfrb,Angpt1,Pdgfb |
| 1.008e-02 | -4.60 | positive regulation of mitotic cell cycle phase transition | biological process | GO:1901992 | 83 | 12 | 20694 | 1406 |
Ccnd1,Pbx1,Rgcc,Tmod3,Mecp2,Hspa2,Ube2e2,Ankrd17,Ccnd2,Cenpe,Ccne1,Mdm2 |
| 1.009e-02 | -4.60 | MicroRNAs in cancer | KEGG pathways | mmu05206 | 279 | 37 | 7931 | 713 |
Ccnd1,Crkl,Pdgfrb,Notch2,Cdkn1a,Myc,Map2k1,Met,Abcb1a,Prkce,Casp3,Plau,Mdm2,Socs1,Ezr,Pim1,Sirt1,Hmga2,Marcks,Itga5,Stat3,Mmp9,Ccne1,Zeb1,Bcl2l11,Ptgs2,Irs2,Notch1,Pdgfb,Spry2,Thbs1,Atm,Ccnd2,Ddit4,Abcc1,Tnc,Nfkb1 |
| 1.009e-02 | -4.60 | MicroRNAs in cancer | KEGG pathways | ko05206 | 279 | 37 | 7931 | 713 |
Map2k1,Myc,Met,Abcb1a,Cdkn1a,Notch2,Pdgfrb,Ccnd1,Crkl,Hmga2,Socs1,Ezr,Sirt1,Pim1,Plau,Mdm2,Prkce,Casp3,Irs2,Notch1,Bcl2l11,Zeb1,Ptgs2,Marcks,Itga5,Stat3,Mmp9,Ccne1,Thbs1,Ccnd2,Atm,Ddit4,Tnc,Abcc1,Nfkb1,Pdgfb,Spry2 |
| 1.011e-02 | -4.59 | Gastrin-CREB signalling pathway via PKC and MAPK | REACTOME pathways | R-MMU-881907 | 390 | 48 | 8608 | 757 |
Cysltr2,Xcr1,Psme2,Psma6,Ptk2,Met,Ptafr,Psmb8,Dgkh,Psme1,Dusp5,Ednrb,Psmb6,Dusp6,Htr2b,Gpr132,Rapgef2,Fpr2,Ccl9,Rasgrp1,Prokr1,Irs2,Htr2a,Ppp2r5a,Edn1,Kitl,Pdgfb,Jak2,Map2k1,Ksr1,Il2rg,Pdgfrb,Lpar1,Psmd10,Rgs3,Psmb10,Gna15,P2ry2,Itpr1,Gpr68,Psmb9,Angpt1,Psme2b,Src,Spred1,Ppp2r1b,Dgka,Prkce |
| 1.011e-02 | -4.59 | GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_DN | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_DN | 172 | 23 | 15632 | 1249 |
Cd69,Ddit4,Srxn1,Csf1,Slc43a3,Nr4a3,Ptafr,Egr3,Hmgcs1,Irak2,Trip10,Itgav,Cd200r4,Chst11,Dusp4,Stap1,Pde1b,Tmtc2,Arrdc4,Nfkbiz,Etv5,Ube2f,Cd80 |
| 1.011e-02 | -4.59 | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_DN | 172 | 23 | 15632 | 1249 |
Slc43a3,Tpx2,Pigv,Egr3,Lif,Cd200,Mcoln2,Stip1,Cd38,Prpf38a,Fscn1,Sdc4,Irf8,Homer1,Cenpj,Rbbp8,Tnf,Ccne1,Slc39a14,Dhx58,Mlkl,Ccdc86,Trip13 |
| 1.011e-02 | -4.59 | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_DN | MSigDB lists | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_DN | 172 | 23 | 15632 | 1249 |
Ext1,Gpr132,Tifa,Jag1,Ptprj,Ptger4,Clec5a,Arf4,Vcam1,Eno1,Tbc1d1,Fut8,Tnc,Tnfsf8,Ccnd1,Gpr68,Magohb,Mcoln2,Icam1,Nlrp3,Aldh1b1,Slc16a1,Prpf4 |
| 1.011e-02 | -4.59 | GSE11924_TFH_VS_TH17_CD4_TCELL_UP | MSigDB lists | GSE11924_TFH_VS_TH17_CD4_TCELL_UP | 172 | 23 | 15632 | 1249 |
Aff1,Slfn5,Orai2,Prkx,Atp11a,Fcho2,Ifit3b,Evl,Fam53c,Vcan,Dusp4,Stx6,Icosl,Gpr132,Gclm,Ampd3,Ifit3,Znfx1,Mcm9,Ppm1k,Arid4a,Crbn,Psip1 |
| 1.011e-02 | -4.59 | HSF_Q6 | MSigDB lists | HSF_Q6 | 172 | 23 | 15632 | 1249 |
Bcl6,Ankrd17,Hspa1a,Hsph1,Mid1,Edn1,Rhoq,Pigv,Jmjd6,Atf3,Csrnp1,Olfml3,Tnks1bp1,C1rl,Map4k4,Dcun1d3,P4ha1,Phf6,Max,Rtn1,Uchl1,Ppp2r2a,Ust |
| 1.011e-02 | -4.59 | GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN | MSigDB lists | GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN | 172 | 23 | 15632 | 1249 |
H3f3b,Rbms1,Rgs1,Traf3ip2,Uba7,Dgka,Btg2,Casp4,Ogfr,Pde4b,Junb,Ikbkg,Aff1,Tnfaip3,Ciapin1,St3gal6,Nxf1,Plk3,Rnf139,Fchsd2,Dusp8,Ezr,Bcl2l11 |
| 1.012e-02 | -4.59 | RTAAACA_FREAC2_01 | MSigDB lists | RTAAACA_FREAC2_01 | 819 | 84 | 15632 | 1249 |
Ifih1,Socs1,Prdm1,Etv5,Pdgfc,Pbx1,Bmp2,Tcf4,Axl,Dusp1,Stk40,Mdm2,Fgl2,Tlk2,Ccnd1,Rhoq,Nr3c1,Map3k8,Frmd4a,Clec4d,Rcan1,Smox,Hcar2,Zhx2,Rcl1,Gcnt2,Lcp2,Gja1,Sesn3,Junb,Arid4a,Maff,Ppp2r3a,Inhba,Vasn,Mmp13,Pdgfb,Ddit4,Ext1,Etv3,Dcp2,Tle3,Zbtb5,Plau,Cited2,Fos,Gpr18,Tet2,Sqstm1,Flrt3,Nr4a1,Klf3,Mid1,Dusp4,Ncoa5,Mllt6,Cept1,Phlpp1,Vcan,Myc,Stap1,Abcb1a,Irf4,Edn1,Kcnj2,Acsl1,Dnajb4,Trib1,Tmod3,Mtmr14,Cdkn1a,Plekhn1,Igf1r,H3f3b,Tagap,Tnip1,Rgs1,Ust,Lmo4,Ptch1,Kctd12,Atxn7l1,Isg20,Spen |
| 1.013e-02 | -4.59 | IRF1_Q6 | MSigDB lists | IRF1_Q6 | 231 | 29 | 15632 | 1249 |
Ciita,Il27,Irs2,Psmb10,Cnot4,Il18bp,Tapbp,Fcgr2b,Casz1,Ezr,Ehd1,Klf6,Gfi1,Lox,Tapbpl,Mmp13,Dgka,Syne2,Trim21,Trip13,H2-Aa,Psme2,Sik3,Osm,Sipa1l1,Lmo4,Jarid2,Rnf31,P4ha1 |
| 1.015e-02 | -4.59 | KAAB_FAILED_HEART_ATRIUM_DN | MSigDB lists | KAAB_FAILED_HEART_ATRIUM_DN | 134 | 19 | 15632 | 1249 |
Daam1,Map2k1,Txn1,Tagln,Slc39a14,Wars,Optn,G3bp2,Stat3,Cnn3,Rab9,Acvr1b,Slco3a1,St3gal1,Ldha,Pgk1,Actb,Prdx1,Clic4 |
| 1.017e-02 | -4.59 | biosynthetic process | biological process | GO:0009058 | 2168 | 174 | 20694 | 1406 |
Samhd1,Dck,Cpeb4,Lox,Phgdh,Mcm9,Pgap2,Hif1a,Il1b,Tmtc2,Pttg1,Polr2g,Tet2,Mppe1,Slc7a2,Hsd17b12,St3gal5,Extl2,Pcx,Alas1,Ifnar1,Pla2g4a,Gys1,Gch1,Denr,Nampt,Serp1,Psat1,Myd88,Egr2,Plaat3,Gfpt1,Plod2,Tha1,Plod3,Egr1,Ext1,Hmgcs1,Fut8,Ampd3,Eif4g2,Odc1,Rbms1,Itpkc,Phlda1,Stat3,Nr3c1,Dpy19l1,Fam111a,Oas1a,Ptafr,Arg2,Ak4,Pdss1,Mcm6,Mthfd1l,Mcm10,Irf7,Pgk1,Inhba,Ptges,Stat1,Sphk1,Tcea1,St3gal1,Dio2,Cept1,Pgs1,Med21,Gtpbp2,Ell2,Eif2ak2,Stat5a,Eef1e1,Ch25h,Fosb,Kmo,Gbe1,Nr1h3,Pdgfrb,Myc,Pde5a,Aff1,Snapc1,Mrpl52,Tpi1,Ldha,Plscr1,Sde2,Degs2,Pik3cd,Timeless,Ptgs2,Mgat1,Oasl2,Fos,Acsl1,Nfil3,Upp1,Atm,Acsl5,Sirt1,Plcl2,Pbx1,Ahr,Lyn,Chst11,Tnip1,St3gal3,Lmo4,Parp10,Taf4b,Asah2,St3gal6,Atf3,Ciapin1,Angpt1,Col4a2,Etnk1,Dse,Tnf,Sod2,Tcf4,Jun,Agpat4,Syk,Lpcat2,Gclc,Cd74,Junb,Lipg,Srm,Nod1,Cdkn2d,Wars,Larp1,Nmi,Smg7,Dgka,Idi1,Ass1,Cmpk2,Ccne1,Hsd17b7,Asns,Gcnt2,Hivep2,B3gnt5,Nos2,Gpd2,Irgm2,Mcmbp,Mthfr,Mocs1,Il18,Plpp1,Lipe,Hinfp,Gmppb,Cnp,Il10,Gk,Pigv,Rars,Tspo,Hdc,Med13,Dhrs9,Cers6,Gclm,Gadd45g,Sgms2,Papss2,Edn1 |
| 1.020e-02 | -4.59 | zinc ion transmembrane transporter activity | molecular function | GO:0005385 | 20 | 5 | 20217 | 1400 |
Slc39a4,Slc39a14,Slc39a13,Slc30a1,Slc30a4 |
| 1.024e-02 | -4.58 | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_DN | MSigDB lists | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_DN | 153 | 21 | 15632 | 1249 |
Itgav,Slc25a37,Jarid2,Hsd17b12,Cenpe,Lap3,Birc2,Timeless,Fchsd2,Plscr1,Syne2,Parp9,Dyrk2,Bcor,Oasl1,Egr3,Tlr2,Ddx58,Kmo,Ust,Prkar2b |
| 1.024e-02 | -4.58 | GSE22045_TREG_VS_TCONV_UP | MSigDB lists | GSE22045_TREG_VS_TCONV_UP | 153 | 21 | 15632 | 1249 |
Psma6,Stx6,Ccng2,Dennd1b,Trim14,Isg20,Sap30,Sipa1l1,Casp8,Cd86,Daam1,N4bp1,Cenpe,Me1,Tnfsf10,Sec24a,Cd83,Sdc4,Cdc42ep4,Tpx2,Tnip3 |
| 1.024e-02 | -4.58 | GSE22886_NAIVE_BCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_DC_UP | 153 | 21 | 15632 | 1249 |
Taf4b,Mid1,Isg20,Zeb1,Phlpp2,Stap1,Gpr18,Klf2,Hopx,Casz1,Dusp1,Slc25a37,Cd38,Rras2,Il15,Fbxo4,Serpinb9,Sell,Endod1,Cd200,Pim2 |
| 1.024e-02 | -4.58 | GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN | 153 | 21 | 15632 | 1249 |
Ehd1,Plac8,Nlrc5,Klf3,Atm,Pdk3,Casp8,Plekha2,Arhgef3,St3gal5,Ntng2,Syne2,Ccng2,Usp35,Optn,Csf3,Adrb2,Cyth3,Pde3b,Whamm,Atp2b4 |
| 1.024e-02 | -4.58 | transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0007178 | 213 | 24 | 20694 | 1406 |
Ptk2,Lnpep,Dcp1a,Sirt1,Gdf15,Egr1,Inhba,Ppm1l,Fut8,Bmp2,Acvr1,Stoml1,Zyx,Pml,Acvrl1,Src,Myd88,Ccl2,Gcnt2,Jun,Fos,Bambi,Acvr1b,Cited2 |
| 1.024e-02 | -4.58 | positive regulation of developmental growth | biological process | GO:0048639 | 213 | 24 | 20694 | 1406 |
Sirt1,C3,Trip10,Hmga2,Notch1,Agrn,Dbnl,Edn1,Serpine1,Pim1,Csf1,Nr3c1,Adrb2,Serp1,Ikzf1,Ezr,Eif4g2,Ptger4,Mecp2,Cyfip1,Stat5a,Hlx,Mul1,Hopx |
| 1.028e-02 | -4.58 | RNase_Zc3h12_NYN | interpro domains | IPR021869 | 7 | 3 | 19984 | 1430 |
N4bp1,Zc3h12c,Zc3h12a |
| 1.028e-02 | -4.58 | Interferon_reg_factor-3 | interpro domains | IPR019471 | 7 | 3 | 19984 | 1430 |
Irf8,Irf4,Irf7 |
| 1.028e-02 | -4.58 | Helicase/UvrB_N | interpro domains | IPR006935 | 7 | 3 | 19984 | 1430 |
Dhx58,Ddx58,Ifih1 |
| 1.028e-02 | -4.58 | PGBDSf | interpro domains | IPR036366 | 7 | 3 | 19984 | 1430 |
Mmp13,Mmp14,Mmp9 |
| 1.028e-02 | -4.58 | Transcription_factor_Maf_fam | interpro domains | IPR024874 | 7 | 3 | 19984 | 1430 |
Mafg,Mafk,Maff |
| 1.028e-02 | -4.58 | Sprouty | interpro domains | IPR007875 | 7 | 3 | 19984 | 1430 |
Spred3,Spred1,Spry2 |
| 1.028e-02 | -4.58 | GS_dom | interpro domains | IPR003605 | 7 | 3 | 19984 | 1430 |
Acvrl1,Acvr1,Acvr1b |
| 1.028e-02 | -4.58 | SAND_dom | interpro domains | IPR000770 | 7 | 3 | 19984 | 1430 |
Sp110,Sp140,Sp100 |
| 1.028e-02 | -4.58 | Syndecan/Neurexin_dom | interpro domains | IPR027789 | 7 | 3 | 19984 | 1430 |
Sdc1,Sdc4,Sdc2 |
| 1.028e-02 | -4.58 | development of primary male sexual characteristics | biological process | GO:0046546 | 114 | 15 | 20694 | 1406 |
Hmga2,Bcl2l11,H3f3b,Insl6,Arid5b,Ccnd1,Nupr1,Icam1,Inhba,Kdr,Gja1,Arid4a,Fndc3a,Crkl,Cited2 |
| 1.032e-02 | -4.57 | GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP | MSigDB lists | GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP | 182 | 24 | 15632 | 1249 |
Asb13,St3gal6,Sell,Smc5,Etnk1,Samhd1,Gng12,Tax1bp1,Rbms2,Slc7a2,Fubp1,Ubr4,Samsn1,Sesn3,Gramd1a,Klf3,Kctd12,4932438A13Rik,Eya4,Tlk2,Sirt1,Kdm5b,Cnn3,Nr3c1 |
| 1.032e-02 | -4.57 | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN | 182 | 24 | 15632 | 1249 |
Adhfe1,Map3k6,Fam43a,Zswim4,Plekha5,Tspan3,Hspa1a,Hmga1,Rai14,Gpr35,Ubash3b,Sdc1,Aldh1b1,Nxf1,Pbx1,Slc48a1,Ube2f,Gda,Psat1,Mfap3l,Rel,Mtdh,Gtpbp2,Zcchc2 |
| 1.032e-02 | -4.57 | GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_DN | 182 | 24 | 15632 | 1249 |
Zhx2,Clic4,Tnfaip2,Map3k8,Nr4a3,Ripk2,Pde7b,Slc7a5,Irf8,Cd274,Birc3,Aff1,Slc25a25,Gclc,Cd74,Plk3,Ifrd1,Cnot4,Mafk,Dock10,Stk40,Irf4,Rbbp8,D16Ertd472e |
| 1.032e-02 | -4.57 | GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_DN | MSigDB lists | GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_DN | 182 | 24 | 15632 | 1249 |
Wdr43,Adam19,Serpinb2,Cflar,Polr2g,Ripk2,Dusp5,Psmb6,Spint2,Il18rap,Dusp6,Nfkb1,Txn1,Traf1,Pnp2,Ccdc86,Gclm,Tiparp,Eno1,Homer1,Srm,Bcl2l11,Hsph1,Tnf |
| 1.032e-02 | -4.57 | GO_PEPTIDASE_REGULATOR_ACTIVITY | MSigDB lists | GO_PEPTIDASE_REGULATOR_ACTIVITY | 182 | 24 | 15632 | 1249 |
Spint2,Prdx5,Mmp14,Slpi,Psme2,Casp3,Ctsc,Serpine1,Birc2,Cav1,Timp1,Tnfsf14,Nlrc4,Casp1,Cst7,Birc3,Crim1,Apaf1,Serpinb2,Nod1,Serpinb9,Pttg1,C3,Psme1 |
| 1.032e-02 | -4.57 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 182 | 24 | 15632 | 1249 |
Gcnt2,Bmp2,Bambi,Acvr1b,F11r,Ppm1l,Ptk2,Egr1,Pml,Inhba,Acvr1,Acvrl1,Fut8,Pdgfb,Fos,Zyx,Cited2,Jun,Src,Gdf15,Ltbp2,Lrp4,Lnpep,Ccl12 |
| 1.032e-02 | -4.57 | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_DN | 182 | 24 | 15632 | 1249 |
Cpd,Ift57,Rhoq,N4bp1,Spsb1,Ppfibp1,Ube2f,Tpx2,Nek6,Slc30a4,Mcm10,AA467197,Egln3,Fam72a,Slc39a14,Plscr1,Asns,Irf8,Gja1,Psat1,Cdkn1a,Ppp2r1b,St7,Mafg |
| 1.033e-02 | -4.57 | GO_REGULATION_OF_HOMEOSTATIC_PROCESS | MSigDB lists | GO_REGULATION_OF_HOMEOSTATIC_PROCESS | 417 | 47 | 15632 | 1249 |
Itpr1,Src,Tnf,Gpr68,Hif1a,Cd74,Isg15,Slc30a4,Pml,Cd38,Ripk3,Tnfaip3,H2-Eb1,Gja1,Ccl5,Inhba,Hap1,Scn1b,Ptgs2,Cxcl10,Nr4a3,Ptger4,Htr2b,Il1b,Hcar2,Sec24a,Kitl,Syk,Pla2g4a,Edn1,Gclm,Prkce,Myc,Ubash3b,Nr1h3,Slc30a1,Pim3,Tspo,Htr2a,Gclc,Cav1,Atm,Ednrb,Acvr1b,Lyn,Ldlr,Kdr |
| 1.035e-02 | -4.57 | neuron projection | cellular component | GO:0043005 | 1492 | 124 | 20747 | 1409 |
Glrx,Casp8,Actb,Cx3cr1,Flrt3,Stxbp1,Cpeb4,Kcna3,Bnip3,Uchl1,Rpgrip1l,Sirt1,Htr2a,Nqo1,Cnn3,Fos,Grk3,Clic5,Cd200,Cdk5r1,Psd,Rhoc,Tnfrsf1b,Agrn,Eno2,Cx3cl1,Rab21,Fzd1,Casp4,Dock4,Eno1,Igf1r,Atp2b4,Ntng2,Mark2,Src,Ass1,Pde4b,Arf4,Orai2,Prnp,Xrn1,Hdc,Prkar2b,Plk2,Adora2a,Dync1h1,Palld,Cd40,Kif5c,Homer1,Hdac1,Fscn1,Lrp4,Apba1,Rapgef2,Optn,Rgs14,Stat1,Adgrl2,Flrt2,Phlpp1,Cyfip1,Ptch1,Eif4g2,Daxx,Itga4,Katna1,Mul1,Igsf8,Kif3c,Pdgfb,Casp1,Myo10,Triobp,Map2k1,Nr3c1,Fcgr2b,Lrp8,Ccl2,Igsf9,Sipa1l1,Tpx2,Map2k4,Stau1,Ctla2a,Lpar1,Adrb2,Fchsd2,Max,Fas,Met,Dock10,Nlgn2,Slc4a7,Rap1gap2,Itpr1,Acp2,Kcnj2,Ero1l,Txn1,Phlpp2,Micall2,Ptger4,Ptgs2,Myc,Acvrl1,Cacybp,Htr2b,Dst,Ptk2,Plk3,Rab3ip,Flnb,Scn1b,Nfkb1,Sphk1,Nrp2,Dbnl,Rac3,Ift57,Hap1,Cacna1d,Kdr |
| 1.037e-02 | -4.57 | GARY_CD5_TARGETS_DN | MSigDB lists | GARY_CD5_TARGETS_DN | 396 | 45 | 15632 | 1249 |
Tuba4a,Ifit1bl2,Fubp1,Ascc3,Daam1,Cd86,Arl5b,Tlr1,Oas1g,Ak4,Stip1,Rcl1,Sp140,Plekhf2,Casp1,Hsph1,Tank,Pnp2,Rhoh,Magohb,Aim2,Kmo,Ube2f,Sgk3,Irf8,Met,Oas1a,Dyrk2,Max,Ifi35,Dnajb4,H3f3b,Sod2,Ifit1bl1,Cited2,Dnaja1,Slc44a1,Fcgr2b,Ikzf1,Cnot4,Chst11,Palld,Rars,Nxf1,Pgm1 |
| 1.040e-02 | -4.57 | TYROBP Causal Network | WikiPathways | WP3625 | 58 | 13 | 4813 | 540 |
Igsf6,Abcc4,Il18,C3,Hlx,Samsn1,Tnfrsf1b,Plek,Hcls1,Rgs1,Stat5a,Il13ra1,Adap2 |
| 1.041e-02 | -4.57 | MODULE_69 | MSigDB lists | MODULE_69 | 449 | 50 | 15632 | 1249 |
Edn1,Mmp14,Ccl2,Fos,Cited2,Hivep2,Morc3,Zbtb5,Slamf7,Phip,Fpr2,Kat2b,Aldh1b1,Pikfyve,Nxf1,Ddx60,Csf1,Trim14,Timeless,Ppp4r2,Plekhg1,Ednrb,Abcc1,Nfil3,Clcf1,Chd9,Tnfsf4,Acvr1,Kdm5b,Sele,Gpr68,Stat3,Arid5a,Cd302,Stat5a,Plekhf2,Ncoa7,Mcmbp,Mapkbp1,Sav1,Smg7,Il1a,Itga4,Prdm1,Hsd17b12,Tuba4a,Gja1,Vegfc,Ptgs2,Larp1 |
| 1.043e-02 | -4.56 | GO_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_PROTEIN_CATABOLIC_PROCESS | 524 | 57 | 15632 | 1249 |
Rnf145,Ldlr,Znrf1,Tmem67,Dnajb2,Lnpep,Rnf14,Atm,Psmb8,Ankib1,Casp8,Ubr4,Psme2,Sirt1,Rnf19a,Usp12,Usp25,Znrf3,Pttg1,Trim13,Fbxo4,Gpc1,Herc3,Chmp4b,Sqstm1,Crbn,Psmd10,Ctsc,Bnip3,Uchl1,Psmb6,Rnf19b,Usp31,Herc6,Usp42,Keap1,Ube2l6,Usp35,Uba7,Rnf139,Pml,Ube2e1,Psme1,Isg15,Psmb10,Usp18,Bfar,Rnf34,Tnfaip3,Birc2,Psmb9,Traf2,Klhl25,Rffl,Rnf24,Psma6,Mdm2 |
| 1.045e-02 | -4.56 | EGF-like_CS | interpro domains | IPR013032 | 192 | 23 | 19984 | 1430 |
Notch2,Itgb8,Plau,Lrp4,F10,Scarf1,Ltbp2,Vcan,Sell,Sele,Ntng2,Tnc,Ldlr,Tmeff1,Jag1,Vasn,Plat,C1ra,Lrp8,Agrn,Thbs1,Notch1,Adam19 |
| 1.047e-02 | -4.56 | ODONNELL_METASTASIS_UP | MSigDB lists | ODONNELL_METASTASIS_UP | 80 | 13 | 15632 | 1249 |
Pik3r5,Nr4a1,Myo1b,Ifna6,Pdlim7,Ksr1,Bcorl1,Ifna5,Dennd2a,Fcgr1,Ifna1,Slc28a2,Ifna2 |
| 1.047e-02 | -4.56 | VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP | MSigDB lists | VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP | 80 | 13 | 15632 | 1249 |
Egln3,Ly75,Plekha2,Slc16a3,Ezr,Pgk1,Etv5,Fam162a,Pfkl,Ier3,Upp1,Ldha,Tpi1 |
| 1.047e-02 | -4.56 | GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | 80 | 13 | 15632 | 1249 |
Hk3,Pfkl,Pgk1,Cmpk2,Hk2,Pfkfb3,Ampd3,Ak4,Eno1,Eno2,Tpi1,Ldha,Hk1 |
| 1.048e-02 | -4.56 | Syndecan | pfam domains | PF01034 | 7 | 3 | 18711 | 1348 |
Sdc2,Sdc1,Sdc4 |
| 1.048e-02 | -4.56 | Sprouty | pfam domains | PF05210 | 7 | 3 | 18711 | 1348 |
Spry2,Spred3,Spred1 |
| 1.048e-02 | -4.56 | IRF-3 | pfam domains | PF10401 | 7 | 3 | 18711 | 1348 |
Irf4,Irf8,Irf7 |
| 1.048e-02 | -4.56 | ResIII | pfam domains | PF04851 | 7 | 3 | 18711 | 1348 |
Dhx58,Ifih1,Ddx58 |
| 1.048e-02 | -4.56 | RNase_Zc3h12a | pfam domains | PF11977 | 7 | 3 | 18711 | 1348 |
Zc3h12a,Zc3h12c,N4bp1 |
| 1.048e-02 | -4.56 | TGF_beta_GS | pfam domains | PF08515 | 7 | 3 | 18711 | 1348 |
Acvr1b,Acvr1,Acvrl1 |
| 1.048e-02 | -4.56 | SAND | pfam domains | PF01342 | 7 | 3 | 18711 | 1348 |
Sp100,Sp140,Sp110 |
| 1.048e-02 | -4.56 | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_DN | 192 | 25 | 15632 | 1249 |
Tmem176a,Cacybp,Slfn4,Atp6v1d,Ifit1bl2,Tor3a,Snx10,Epsti1,Slfn3,Bcl2a1a,Ccl4,Odc1,Hmgcs1,Dck,Bcl2a1d,Cers6,Stard5,Psmd10,Ifit1bl1,Bcl2a1b,Rnf114,Daxx,Prdx1,Agtrap,Nck1 |
| 1.052e-02 | -4.55 | organic substance biosynthetic process | biological process | GO:1901576 | 2088 | 168 | 20694 | 1406 |
Ifnar1,Alas1,Lmo4,Tnip1,St3gal3,Pcx,Lyn,Chst11,Pbx1,Ahr,Extl2,Plcl2,Hsd17b12,St3gal5,Sirt1,Polr2g,Tet2,Mppe1,Acsl5,Pttg1,Il1b,Tmtc2,Nfil3,Upp1,Atm,Pgap2,Hif1a,Acsl1,Mcm9,Oasl2,Fos,Lox,Phgdh,Mgat1,Ptgs2,Cpeb4,Degs2,Timeless,Pik3cd,Ldha,Plscr1,Dck,Sde2,Tpi1,Mrpl52,Samhd1,Fut8,Larp1,Hmgcs1,Ext1,Wars,Srm,Nod1,Cdkn2d,Egr1,Plod3,Lipg,Junb,Tha1,Cd74,Plod2,Gclc,Lpcat2,Syk,Gfpt1,Egr2,Plaat3,Agpat4,Jun,Tcf4,Tnf,Dse,Etnk1,Serp1,Col4a2,Angpt1,Myd88,Psat1,Nampt,Denr,Atf3,Taf4b,Parp10,Asah2,St3gal6,Gch1,Gys1,Pla2g4a,Tcea1,Sphk1,Lipe,Stat1,Ptges,Plpp1,Irf7,Pgk1,Inhba,Mcm10,Il18,Mthfd1l,Mcm6,Mocs1,Pdss1,Ak4,Ptafr,Arg2,Mcmbp,Mthfr,Oas1a,Irgm2,Dpy19l1,Gpd2,Fam111a,Nr3c1,B3gnt5,Phlda1,Hivep2,Stat3,Gcnt2,Hsd17b7,Rbms1,Asns,Itpkc,Cmpk2,Ccne1,Odc1,Ass1,Idi1,Dgka,Smg7,Nmi,Ampd3,Eif4g2,Edn1,Snapc1,Papss2,Sgms2,Aff1,Gadd45g,Myc,Gclm,Pde5a,Pdgfrb,Cers6,Med13,Dhrs9,Nr1h3,Fosb,Ch25h,Gbe1,Kmo,Eef1e1,Hdc,Stat5a,Tspo,Eif2ak2,Ell2,Rars,Gtpbp2,Med21,Cept1,Gk,Pgs1,Pigv,Cnp,Il10,Hinfp,St3gal1 |
| 1.055e-02 | -4.55 | ESC_V6.5_UP_EARLY.V1_DN | MSigDB lists | ESC_V6.5_UP_EARLY.V1_DN | 163 | 22 | 15632 | 1249 |
Nupr1,Plau,Col4a2,Gys1,Pbx1,Gbp2,Axl,Tagln,Ddhd1,Oaf,Tnc,Socs3,Lox,Plcl2,Junb,Csrp1,Cav1,Fzd5,Serpine1,Htra1,Degs2,Inhba |
| 1.055e-02 | -4.55 | GSE34515_CD16_NEG_VS_POS_MONOCYTE_DN | MSigDB lists | GSE34515_CD16_NEG_VS_POS_MONOCYTE_DN | 163 | 22 | 15632 | 1249 |
Irf4,Ddit4,Tnfsf8,Slc7a5,Pde7b,Eef1e1,Spint2,Gna15,Rrs1,Heatr6,Ciita,Rbms2,Ppp2r1b,Asf1a,Clcn5,Cd38,Prkar2b,Ahr,Lrrc8c,Ms4a6d,Tulp3,Sell |
| 1.055e-02 | -4.55 | GSE9960_HEALTHY_VS_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_HEALTHY_VS_SEPSIS_PBMC_UP | 163 | 22 | 15632 | 1249 |
Golga3,Igsf8,Hopx,Ubr4,Tnfsf14,Egln3,Mmp13,Slamf9,Pdlim7,Srxn1,Csf1,Mob3b,Pim2,Rac3,Smox,Keap1,Rhof,Gpr68,Rhoq,Slc44a1,Tnc,Pttg1 |
| 1.055e-02 | -4.55 | mouse chr11 C|11 50.3 cM | chromosome location | mouse chr11 C|11 50.3 cM | 3 | 2 | 24173 | 1464 |
Slfn2,Slfn1 |
| 1.055e-02 | -4.55 | mouse chr3 H1|3 66.69 cM | chromosome location | mouse chr3 H1|3 66.69 cM | 3 | 2 | 24173 | 1464 |
Gbp2b,Gbp2 |
| 1.055e-02 | -4.55 | mouse chr1 A2|1 2.08 cM | chromosome location | mouse chr1 A2|1 2.08 cM | 3 | 2 | 24173 | 1464 |
Rrs1,Sgk3 |
| 1.056e-02 | -4.55 | Arginine and proline metabolism | KEGG pathways | ko00330 | 49 | 10 | 7931 | 713 |
Nos2,Smox,Srm,Aldh1b1,Arg2,P4ha2,Lap3,P4ha1,Odc1,Sat1 |
| 1.056e-02 | -4.55 | Arginine and proline metabolism | KEGG pathways | mmu00330 | 49 | 10 | 7931 | 713 |
P4ha1,Sat1,Odc1,Lap3,Srm,P4ha2,Arg2,Aldh1b1,Smox,Nos2 |
| 1.056e-02 | -4.55 | PID_AR_TF_PATHWAY | MSigDB lists | PID_AR_TF_PATHWAY | 63 | 11 | 15632 | 1249 |
Egr1,Src,Jun,Map2k4,Dnaja1,Rel,Kat2b,Nr3c1,Sirt1,Hdac1,Mdm2 |
| 1.056e-02 | -4.55 | GO_MONOSACCHARIDE_BINDING | MSigDB lists | GO_MONOSACCHARIDE_BINDING | 63 | 11 | 15632 | 1249 |
Phyh,Plod2,P4ha2,Hk1,P4ha1,Plod3,Hk3,Pfkl,Hk2,Egln3,Gys1 |
| 1.056e-02 | -4.55 | ELVIDGE_HIF1A_TARGETS_UP | MSigDB lists | ELVIDGE_HIF1A_TARGETS_UP | 63 | 11 | 15632 | 1249 |
Jak2,Ccdc86,Hsph1,Hhex,Tor3a,Scyl2,Srm,Gch1,Slco3a1,Rrs1,Dnaja1 |
| 1.058e-02 | -4.55 | TTGCACT_MIR130A_MIR301_MIR130B | MSigDB lists | TTGCACT_MIR130A_MIR301_MIR130B | 365 | 42 | 15632 | 1249 |
Rnf145,Irf1,Acsl1,Cpeb4,Rtn1,Dcbld2,Pmepa1,Ldlr,Chd9,Rap2c,Mier3,Lnpep,Gja1,Snx2,G3bp2,Cd69,Stx6,Csf1,Spen,Nrp2,Atp11a,Lrp8,Gda,Clcn5,Mdfic,Pfkfb3,Itpr1,Rbbp8,Hivep2,Ppp6r1,Lrp4,N4bp1,Abcc5,Cnot4,Acvr1,Mecp2,Psd,Mllt6,Zfp800,D1Ertd622e,Slc44a1,Peli1 |
| 1.061e-02 | -4.55 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_UP | 144 | 20 | 15632 | 1249 |
Msr1,Dusp6,Tshz1,Dach1,Ttc9c,Spint2,Stat4,Rbpms,Rtn2,Rhoq,Nrp2,Socs1,Kif3c,Slco3a1,Parp3,Tlr3,Pdgfc,Rbms2,Fam102b,Il1rn |
| 1.061e-02 | -4.55 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_DN | 144 | 20 | 15632 | 1249 |
Dusp1,Gem,Il6,Icosl,Ddit4,Dusp4,Rhou,Maff,Hivep3,Dusp5,Dram1,Arl5c,Ppm1l,Nlrp3,Osbpl3,Tle3,Agpat4,Il15ra,Plaur,Rgs3 |
| 1.061e-02 | -4.55 | regulation of protein dephosphorylation | biological process | GO:0035304 | 125 | 16 | 20694 | 1406 |
Ppp1r14b,Ppp1r15a,Pdgfrb,Swap70,Rcan1,Ppp4r2,Ppp2r2a,Ppp2r3a,Ppp1r15b,Phactr4,Ppp2r1b,Vcan,Jak2,Ppp6r1,Ppp2r5a,Tnf |
| 1.067e-02 | -4.54 | PU1_Q6 | MSigDB lists | PU1_Q6 | 212 | 27 | 15632 | 1249 |
Nck1,Nr1h3,Cx3cl1,Fcgr1,Pbx1,Ccdc88b,Znfx1,Fut8,Stap1,Acvrl1,I830077J02Rik,Tmem229b,Il18,Lyn,Rab20,Nfkb2,Mob3c,Sec24b,Birc3,Jarid2,Sesn3,Lcp2,Irf8,Sik3,Slc9a1,Csf1,Piezo1 |
| 1.067e-02 | -4.54 | BILD_E2F3_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_E2F3_ONCOGENIC_SIGNATURE | 212 | 27 | 15632 | 1249 |
Ak4,Dck,Il1b,Cmpk2,Plcl2,Ptch1,Gch1,Tshz1,Ccne1,Eno2,Fzd1,Slc25a12,Prrg4,Bcor,Stxbp1,Slc30a4,Tnfaip3,Cd83,Pfkfb3,Tmem200b,Psip1,Bcl2l11,Lrp4,Dpy19l1,D1Ertd622e,Tnc,Mdn1 |
| 1.067e-02 | -4.54 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | 212 | 27 | 15632 | 1249 |
Myadm,Igsf8,Ddit4,Scn1b,Pdlim7,Vasn,Degs2,Vasp,Dck,Trib3,Lox,Pdzd11,Tnfaip2,Ikbke,Klf6,Casp1,Spic,Tcf4,Ggct,Phgdh,Rai14,Fpr2,F11r,Plau,Rnd3,Cd34,Slc48a1 |
| 1.067e-02 | -4.54 | positive regulation of cellular carbohydrate metabolic process | biological process | GO:0010676 | 64 | 10 | 20694 | 1406 |
Prkce,Ranbp2,Kat2b,Irs2,Hif1a,Ptafr,Sirt1,Dyrk2,Src,Ptpn2 |
| 1.067e-02 | -4.54 | mammary gland epithelium development | biological process | GO:0061180 | 64 | 10 | 20694 | 1406 |
Stat5a,Pml,Kdm5b,Csf1,Ccnd1,Nr3c1,Src,Hif1a,Jak2,Ptch1 |
| 1.068e-02 | -4.54 | ABC1_TM_dom | interpro domains | IPR011527 | 27 | 6 | 19984 | 1430 |
Tap1,Abcc5,Abcc4,Abcb1a,Tap2,Abcc1 |
| 1.070e-02 | -4.54 | GO_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | 89 | 14 | 15632 | 1249 |
Src,Psmd10,Pdgfb,Casp3,Ccnd1,Hspa2,Hhex,Cdkn2d,Pim1,Ccnd2,Kat2b,Cdk5r1,Cdkn1a,Tnfaip3 |
| 1.072e-02 | -4.54 | STOSSI_RESPONSE_TO_ESTRADIOL | MSigDB lists | STOSSI_RESPONSE_TO_ESTRADIOL | 39 | 8 | 15632 | 1249 |
Nr4a3,Ptgs2,Gja1,Pde4b,Birc3,Tle3,Cd34,Pla2g4a |
| 1.072e-02 | -4.54 | WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_H2O2 | MSigDB lists | WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_H2O2 | 39 | 8 | 15632 | 1249 |
Marcksl1,Ccr1,Cdkn2d,Jun,Tank,Il18,Spry2,Myc |
| 1.073e-02 | -4.54 | C-type_lectin-like | interpro domains | IPR001304 | 119 | 16 | 19984 | 1430 |
Clec4e,Olr1,Clec4n,Clec4a1,Klrk1,Cd302,Cd69,Sele,Sell,Clec2d,Vcan,Clec4d,Klra2,Clec5a,Ly75,Layn |
| 1.074e-02 | -4.53 | GO_RESPONSE_TO_CALCIUM_ION | MSigDB lists | GO_RESPONSE_TO_CALCIUM_ION | 107 | 16 | 15632 | 1249 |
Ptges,Clic4,Thbs1,Sdc1,Ccnd1,Slc25a12,Il6,Pla2g4a,Edn1,Fosb,Jun,Fos,Cav1,Homer1,Junb,Dusp1 |
| 1.079e-02 | -4.53 | - | gene3d domains | 1.20.1270.10 | 11 | 4 | 8819 | 755 |
Hsph1,Hspa1a,Hspa2,Hspa1b |
| 1.081e-02 | -4.53 | GSE23568_ID3_KO_VS_WT_CD8_TCELL_UP | MSigDB lists | GSE23568_ID3_KO_VS_WT_CD8_TCELL_UP | 173 | 23 | 15632 | 1249 |
Cst7,Bcl2l11,Sod2,Plac8,Rhoq,Gclm,Cpd,Fgl2,Mcoln2,Hhex,Gmppb,Sass6,Pttg1,Ahr,Ccl5,Txn1,Rgl1,Trip13,Psmb6,Slc31a1,Map3k8,Adam19,Dusp16 |
| 1.081e-02 | -4.53 | GSE3039_NKT_CELL_VS_B1_BCELL_UP | MSigDB lists | GSE3039_NKT_CELL_VS_B1_BCELL_UP | 173 | 23 | 15632 | 1249 |
Rnf24,Pde1b,Cebpd,Samd9l,Vcan,Ogfrl1,Fgl2,4932438A13Rik,Mark2,Tuba4a,S100a8,Abtb2,Slfn4,Atxn7l1,Itga5,Pdzd11,Rcsd1,Adam19,Slfn3,Jak2,Znrf1,Tfec,Dusp16 |
| 1.081e-02 | -4.53 | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_DN | 173 | 23 | 15632 | 1249 |
Cx3cr1,Aoah,Abcc5,Cst7,P2ry13,Extl2,Samhd1,Angpt1,Myo10,Etv3,Ccl22,Fabp7,Antxr1,Htra1,Etv6,Clic5,Itgal,Dmwd,Cmklr1,Dcbld2,Sema4c,Oasl1,Lox |
| 1.081e-02 | -4.53 | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_DN | 173 | 23 | 15632 | 1249 |
Il18rap,Stat4,Phlda1,Tnfsf14,Cd274,Slc13a3,Psmb8,Pdk3,Jarid2,Ccl4,Tapbp,Dusp2,1110038F14Rik,Srm,Spryd7,Ifnar1,Phldb1,Cd80,Cutc,Rnf135,Gbp3,Usp25,Mcoln2 |
| 1.084e-02 | -4.52 | GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 788 | 81 | 15632 | 1249 |
Nox1,Etnk1,Tlr9,Mtmr14,Itpkc,Dck,Mppe1,Gpd2,Pik3cd,Gfpt1,Idi1,Agpat4,Pfkl,Atm,Eno2,Hk1,Ampd3,Plscr1,Oas1a,Smpdl3b,Pgs1,Tpi1,Pgm1,Sgms2,Pikfyve,Papss2,Irs2,Pfkfb3,Slc25a25,Lpcat2,Pde3b,Cd80,Hk3,Me1,Samhd1,Pik3r5,Pla2g4a,Slc44a1,Cept1,Pde5a,Ldha,Oas1g,Ak4,Ptafr,Inpp1,Kitl,Plaur,Htr2b,Pgk1,Cmpk2,Nampt,Plek,Pde4b,Gch1,Cd86,Cnp,Pdgfrb,Pik3r6,Inpp5b,Pdgfb,Adora2a,Oas2,Hk2,Pde7b,Kmo,Calcrl,Upp1,Pigv,Lipg,Gda,Ddhd1,Acpp,Hspa1a,Eno1,Cycs,Minpp1,Pnp2,Pde1b,Rhoq,Mecp2,Prdx5 |
| 1.087e-02 | -4.52 | IGc1 | smart domains | SM00407 | 59 | 11 | 9567 | 823 |
H2-T22,H2-Q6,H2-Aa,H2-Ab1,H2-T10,Tapbpl,H2-Q4,H2-Eb1,H2-Q7,H2-M2,H2-T24 |
| 1.092e-02 | -4.52 | GO_SINGLE_STRANDED_RNA_BINDING | MSigDB lists | GO_SINGLE_STRANDED_RNA_BINDING | 55 | 10 | 15632 | 1249 |
Ddx58,Ifih1,Jmjd6,Nxf1,Ddx60,Rbpms,Dhx58,Polr2g,Pnpt1,Zfp36 |
| 1.095e-02 | -4.51 | epithelial tube formation | biological process | GO:0072175 | 158 | 19 | 20694 | 1406 |
Casp8,Sdc4,Lhx2,Sec24b,Ift57,Apaf1,Mthfd1l,Vasp,Fzd1,Tulp3,Phactr4,Cited2,Casp3,Lmo4,Mthfr,Ptch1,Spint2,Sema4c,Hif1a |
| 1.095e-02 | -4.51 | ZHANG_BREAST_CANCER_PROGENITORS_DN | MSigDB lists | ZHANG_BREAST_CANCER_PROGENITORS_DN | 135 | 19 | 15632 | 1249 |
Hck,Mdfic,Armc8,Tnfaip2,Il18,Pik3cd,Nfkbiz,Malt1,Fndc3a,Socs3,Cpd,Tapbp,Csf1,Phgdh,Atxn7l1,Flnb,Klhl25,Plod3,Map4k4 |
| 1.098e-02 | -4.51 | 3',5'-cyclic-nucleotide phosphodiesterase activity | molecular function | GO:0004114 | 28 | 6 | 20217 | 1400 |
Pde4b,Pde7b,Prkar2b,Pde5a,Pde1b,Pde3b |
| 1.098e-02 | -4.51 | MHCCLASSI | prints domains | PR01638 | 39 | 7 | 5821 | 374 |
H2-T10,H2-Q7,H2-T22,H2-Q6,H2-M2,H2-Q4,H2-T24 |
| 1.099e-02 | -4.51 | GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_WITH_EGR2_DELETED_DN | MSigDB lists | GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_WITH_EGR2_DELETED_DN | 154 | 21 | 15632 | 1249 |
Ikbkg,Tmem200b,Cdyl,Dnaja1,Tiparp,Egr2,Stat3,Rhou,I830077J02Rik,Slamf9,Oas1a,Glipr2,Oas1g,Ttc39b,Adrb2,Adora2b,Cmpk2,Atp11b,Mvp,Rgs3,Stard7 |
| 1.099e-02 | -4.51 | GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_UP | MSigDB lists | GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_UP | 154 | 21 | 15632 | 1249 |
Stoml1,Tnc,Slpi,Rab9,Plk2,Lcp2,Otud1,Epsti1,Kif9,Gng11,Lpcat2,Trib3,Etv3,4930453N24Rik,Ptafr,Cxcl10,Kif3c,Fam111a,Egr3,Kdm6b,Palld |
| 1.099e-02 | -4.51 | visual system development | biological process | GO:0150063 | 380 | 38 | 20694 | 1406 |
Jun,P2ry12,Jag1,Gpd2,Lif,Cited2,Phactr4,Pdgfb,Tulp3,Slc25a25,Casz1,Hif1a,Kdr,Flt1,Zfp513,Prdm1,Hdac1,Lhx2,Stat3,Ikzf1,Acvrl1,Jmjd6,Inhba,Zhx2,Notch2,Rcn1,Ahr,Tdrd7,Clic4,Gja1,Tsku,C3,Ppp2r3a,Zeb1,Rpgrip1l,Pdgfrb,Fzd5,Slc4a7 |
| 1.100e-02 | -4.51 | regulation of insulin receptor signaling pathway | biological process | GO:0046626 | 74 | 11 | 20694 | 1406 |
Socs3,Cish,Socs1,Ncoa5,Sesn3,Ptpn2,Src,Sirt1,Nck1,Il1b,Pid1 |
| 1.100e-02 | -4.51 | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | MSigDB lists | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | 345 | 40 | 15632 | 1249 |
Oasl1,Itpkc,Gng4,Pik3cd,Cdc42ep4,Lpar1,Actb,Snn,Ptges,Plaur,Dcbld2,Ltbp2,Gna15,Col11a2,Rel,Klf2,Flrt2,Phlda1,Sap30,Pdgfb,Nrp2,Pou2f2,Vasp,Tnfrsf8,Cd80,Pde3b,Apaf1,Pik3r5,Plekha5,Tnf,Nr4a1,Gadd45b,Dusp1,Casz1,Mmp14,Dusp8,Rab11fip1,Nqo1,Ppfia3,Triobp |
| 1.101e-02 | -4.51 | GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_DN | MSigDB lists | GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_DN | 183 | 24 | 15632 | 1249 |
Klf6,Fos,Slc15a3,Ccnd1,Mxd1,Ier2,Csrnp1,Tspo,Klf7,Hck,Tle3,Nfkb1,Procr,Piezo1,Vasp,Stx6,Ebi3,Acvr1b,Plcl2,Znrf1,Fscn1,Kdr,Pkp4,Lrrc8c |
| 1.101e-02 | -4.51 | GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_DN | MSigDB lists | GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_DN | 183 | 24 | 15632 | 1249 |
Slc48a1,Pde3b,Fas,Ddx60,Slco3a1,Calcrl,Ccnd2,Ly75,Peli1,Tnfsf8,Cish,Cers6,Zyx,Gpsm2,Inpp1,Tnfsf10,Znrf1,Smox,Mthfd2,Inpp5b,Dgka,Rnf19a,Dcun1d3,Lad1 |
| 1.101e-02 | -4.51 | RIZKI_TUMOR_INVASIVENESS_3D_UP | MSigDB lists | RIZKI_TUMOR_INVASIVENESS_3D_UP | 183 | 24 | 15632 | 1249 |
Dhrs9,Cnn2,Jun,Arid5a,Dusp2,Egr2,Tnc,Ikzf1,Rhoh,Irs2,Tap2,Csf1,Cd69,Etv6,Mmp13,Stoml1,Filip1l,Ptk2,St7,Map2k4,Ptafr,Tnfsf10,Inpp1,Igf1r |
| 1.101e-02 | -4.51 | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_DN | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_DN | 183 | 24 | 15632 | 1249 |
Casp4,Gem,Mmd,Ube2e2,Pou2f2,Dnajb4,Fam111a,Dram1,Vegfc,Hcar2,Gfi1,5430427O19Rik,Slfn9,Tnfsf10,Ifit2,Crbn,Agrn,Casp1,Rin2,Slfn8,Rhoh,Sdc4,Pilra,Plau |
| 1.101e-02 | -4.51 | GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | MSigDB lists | GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | 183 | 24 | 15632 | 1249 |
Trp53i11,Lrp8,Rnf19b,Fas,Nr4a3,Mthfd2,Phf6,Slc43a3,Aida,Rab9,Atxn7l1,Slc15a3,Fchsd2,Ift57,Prdx5,Dusp4,Hivep3,Hdac1,Brwd3,Csrp1,Plek,Cited2,Dmwd,Rel |
| 1.101e-02 | -4.51 | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_DN | 183 | 24 | 15632 | 1249 |
Spata13,Prnp,Papss2,Pfkfb3,Pim3,Slc2a1,Cnn2,Plekha5,Rhoq,Trib1,Tgfbi,Acvr1b,Adora2b,Tlr2,Acp2,Zc3h12c,Cav1,Slc7a2,Stat4,Csf3,Cxcl2,Maff,Srxn1,Pdlim7 |
| 1.103e-02 | -4.51 | MODULE_259 | MSigDB lists | MODULE_259 | 47 | 9 | 15632 | 1249 |
Il4ra,Il2rg,Csf3r,Cdk5r1,Pdgfrb,Axl,Ccl12,Il13ra1,Cdkn1a |
| 1.103e-02 | -4.51 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | MSigDB lists | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | 47 | 9 | 15632 | 1249 |
Agrn,Sdc1,Dse,Sdc4,Ust,Gpc1,Vcan,Chst11,Sdc2 |
| 1.103e-02 | -4.51 | HENDRICKS_SMARCA4_TARGETS_DN | MSigDB lists | HENDRICKS_SMARCA4_TARGETS_DN | 47 | 9 | 15632 | 1249 |
Spry2,Nrp2,Kcnj2,Fchsd2,Myc,Asns,Cd74,Ccr1,Ltbp2 |
| 1.103e-02 | -4.51 | REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT | MSigDB lists | REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT | 47 | 9 | 15632 | 1249 |
Psmb9,Psmd10,Psmb10,Psmb8,Atm,Psme1,Psmb6,Psma6,Psme2 |
| 1.103e-02 | -4.51 | LEE_TARGETS_OF_PTCH1_AND_SUFU_UP | MSigDB lists | LEE_TARGETS_OF_PTCH1_AND_SUFU_UP | 47 | 9 | 15632 | 1249 |
Magohb,Mcm6,Mthfd2,Lap3,Ccnd2,H2-Aa,Rnd3,Hk2,Ccnd1 |
| 1.103e-02 | -4.51 | GO_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION | 47 | 9 | 15632 | 1249 |
Ptk2,Ptprj,Src,Acvrl1,Thbs1,Mmp14,Kdr,Sdc4,Slc9a1 |
| 1.105e-02 | -4.51 | LUZP1 (leucine zipper protein 1) | protein interactions | 7798 | 15 | 5 | 7778 | 753 |
Actb,Itga5,Tpx2,Flnb,Tmod3 |
| 1.106e-02 | -4.50 | Heat_shock_70_CS | interpro domains | IPR018181 | 13 | 4 | 19984 | 1430 |
Hsph1,Hspa2,Hspa1b,Hspa1a |
| 1.106e-02 | -4.50 | Hsp_70_fam | interpro domains | IPR013126 | 13 | 4 | 19984 | 1430 |
Hsph1,Hspa1a,Hspa2,Hspa1b |
| 1.106e-02 | -4.50 | Interleukin-10 signaling | REACTOME pathways | R-MMU-6783783 | 6 | 3 | 8608 | 757 |
Tyk2,Stat3,Il10 |
| 1.107e-02 | -4.50 | basolateral plasma membrane | cellular component | GO:0016323 | 226 | 25 | 20747 | 1409 |
Hspa1a,Nod1,Pdzd11,Tlr9,Cd38,Pdgfb,Ezr,Itga9,Ptk2,Abcc1,P2ry12,P2ry2,Slc9a1,Atp2b4,Cav1,Abcc4,Nod2,Stxbp3,Met,Slc4a7,Ldlr,Pdpn,Cd34,Slco3a1,Slc2a1 |
| 1.108e-02 | -4.50 | CD28 co-stimulation | REACTOME pathways | R-MMU-389356 | 29 | 7 | 8608 | 757 |
Map3k8,Cd86,Rictor,Cd80,Trib3,Lyn,Src |
| 1.109e-02 | -4.50 | GO_ORGAN_MORPHOGENESIS | MSigDB lists | GO_ORGAN_MORPHOGENESIS | 811 | 83 | 15632 | 1249 |
Setdb2,Stat3,Tnc,Stk40,Kdm5b,Acvr1,Errfi1,Hdac1,Mdm2,Plod3,Lrp4,Tnf,Src,Csf3r,Serp1,Bmp2,Pbx1,Sav1,Tsku,Notch1,Pdgfc,Csrnp1,Pml,Lif,Prdm1,Hlx,Hhex,Hif1a,Tulp3,Ppp2r3a,Fzd1,Mmp13,Inhba,Tshz1,Gja1,Mthfd1l,Pdgfrb,Map2k1,Flrt2,Fzd5,Prkx,Htr2b,Sec24b,Vegfc,Crkl,Nr4a3,Arid5b,Mmp14,Il6,Myc,Spry2,Edn1,Ift57,Phactr4,Chst11,Ccl12,Syk,Bcl2l11,Ezr,Jun,Cited2,Tiparp,Tet2,Tle3,Col18a1,Bcor,Tmem176b,Evl,Abr,Sdc1,Htra1,Csf1,Zeb1,Tdrd7,Jag1,Clic5,Ptch1,Sema3c,Cav1,Fam20c,Col27a1,Notch2,Ptk2 |
| 1.111e-02 | -4.50 | CTDL_fold | interpro domains | IPR016187 | 140 | 18 | 19984 | 1430 |
Klrk1,Clec4a1,Cd302,Col18a1,Clec4e,Clec4n,Olr1,Klra2,Clec4d,Col4a2,Layn,Ly75,Clec5a,Sell,Sele,Cd69,Vcan,Clec2d |
| 1.116e-02 | -4.50 | B30 | interpro domains | IPR001870 | 80 | 12 | 19984 | 1430 |
Trim34a,Rnf135,Spryd7,Trim30d,Mid1,Trim12c,Spsb1,Trim21,Trim14,Trim30a,Trim36,Trim26 |
| 1.117e-02 | -4.49 | NIK-->noncanonical NF-kB signaling | REACTOME pathways | R-MMU-5676590 | 58 | 11 | 8608 | 757 |
Psma6,Psme2,Psmb6,Psme2b,Psme1,Relb,Psmd10,Psmb9,Psmb8,Nfkb2,Psmb10 |
| 1.117e-02 | -4.49 | Dectin-1 mediated noncanonical NF-kB signaling | REACTOME pathways | R-MMU-5607761 | 58 | 11 | 8608 | 757 |
Psme2b,Psme1,Relb,Psmd10,Psma6,Psme2,Psmb6,Psmb10,Psmb9,Psmb8,Nfkb2 |
| 1.120e-02 | -4.49 | HALLMARK_CHOLESTEROL_HOMEOSTASIS | MSigDB lists | HALLMARK_CHOLESTEROL_HOMEOSTASIS | 72 | 12 | 15632 | 1249 |
Plscr1,Jag1,Errfi1,Pdk3,Ldlr,Idi1,Plaur,Nfil3,Hsd17b7,Hmgcs1,Atf3,Trib3 |
| 1.120e-02 | -4.49 | KEGG_VEGF_SIGNALING_PATHWAY | MSigDB lists | KEGG_VEGF_SIGNALING_PATHWAY | 72 | 12 | 15632 | 1249 |
Mapkapk2,Rac3,Ptk2,Sphk1,Pik3cd,Ptgs2,Kdr,Pik3r5,Src,Map2k1,Akt3,Pla2g4a |
| 1.121e-02 | -4.49 | positive regulation of cell cycle arrest | biological process | GO:0071158 | 37 | 7 | 20694 | 1406 |
Casp2,Pml,Cdkn1a,Crlf3,Cdk5r1,Rgcc,Mdm2 |
| 1.121e-02 | -4.49 | T cell homeostasis | biological process | GO:0043029 | 37 | 7 | 20694 | 1406 |
Fas,Ripk3,Ahr,Pmaip1,Stat5a,Bcl2l11,Casp3 |
| 1.121e-02 | -4.49 | regulation of endothelial cell differentiation | biological process | GO:0045601 | 37 | 7 | 20694 | 1406 |
Jag1,Notch1,Zeb1,Il1b,Tnf,S1pr2,Acvrl1 |
| 1.124e-02 | -4.49 | HDc | smart domains | SM00471 | 23 | 6 | 9567 | 823 |
Pde3b,Pde5a,Samhd1,Pde4b,Pde1b,Pde7b |
| 1.125e-02 | -4.49 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | 253 | 31 | 15632 | 1249 |
Srxn1,Cnn3,Trip13,Psme2,Inhba,G3bp2,Ikbkg,Tuba4a,Cav1,Daam1,Thbs1,Adam19,Pmepa1,Naa25,Tgfbi,Phgdh,Pnp2,Cox17,Vcan,Psma6,Axl,Ezr,Apobec3,Lrp4,Tcf4,Rnd3,Klf7,Crim1,Me1,Palld,Lrp8 |
| 1.126e-02 | -4.49 | GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 126 | 18 | 15632 | 1249 |
Cd74,Grina,Hif1a,Nck1,Nox1,Mmp9,Cdkn2d,Plaur,Ripk3,Plagl2,Cav1,Ptpn2,Src,Hsph1,S100a8,Bcl2l11,Sod2,Sirt1 |
| 1.126e-02 | -4.49 | CRX_DN.V1_UP | MSigDB lists | CRX_DN.V1_UP | 126 | 18 | 15632 | 1249 |
Tmem229b,Arg2,Ier3,Dusp14,Tnfaip3,Trafd1,Slc25a25,Hcls1,Ttc39c,Hspa1a,Gpsm2,Rabgef1,Ddhd1,Plekhf2,Bst1,Jag1,Batf2,Nat2 |
| 1.130e-02 | -4.48 | GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP | MSigDB lists | GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP | 164 | 22 | 15632 | 1249 |
Sh3bp4,Ccdc25,Rtn2,Tmeff1,Spry2,Lcn2,Cited2,Rims3,Lad1,Tnfsf14,Plk2,Itgal,Pik3r5,Me1,Plagl2,Mark2,Rsbn1,Ier3,Pttg1,Prdm9,Sema4c,Rars |
| 1.130e-02 | -4.48 | GO_LAMELLIPODIUM | MSigDB lists | GO_LAMELLIPODIUM | 164 | 22 | 15632 | 1249 |
Itgav,Swap70,Cyfip1,Dbnl,Pdpn,Phactr4,Palld,Evl,Spata13,Myo10,Rab3ip,Antxr1,Piezo1,Slc9a1,Syne2,Vasp,Slc39a14,Snx2,Rac3,Ptk2,Mefv,Fscn1 |
| 1.132e-02 | -4.48 | HSP70 | pfam domains | PF00012 | 13 | 4 | 18711 | 1348 |
Hspa1b,Hspa2,Hspa1a,Hsph1 |
| 1.134e-02 | -4.48 | STAT5A_03 | MSigDB lists | STAT5A_03 | 233 | 29 | 15632 | 1249 |
Psma6,Prkce,Bbx,Stat3,Bcl6,Tcf4,Flrt3,N4bp1,Flt1,Dnase1l3,Olfml3,Tle3,Angpt1,Spred1,Pde3b,Gnb4,Fgr,Zfp281,Tab2,Ppp2r3a,Etv6,Lmo4,Cd274,Map4k4,Kitl,Nr4a3,Pim1,Kcna3,Rcan1 |
| 1.137e-02 | -4.48 | NUMB (NUMB endocytic adaptor protein) | protein interactions | 8650 | 10 | 4 | 7778 | 753 |
Jun,Mdm2,Flnb,Notch1 |
| 1.137e-02 | -4.48 | ARHGAP21 (Rho GTPase activating protein 21) | protein interactions | 57584 | 10 | 4 | 7778 | 753 |
Tmod3,Flnb,Actb,Cenpe |
| 1.138e-02 | -4.48 | TTCYRGAA_UNKNOWN | MSigDB lists | TTCYRGAA_UNKNOWN | 294 | 35 | 15632 | 1249 |
Stat4,Jag1,Hat1,Pdgfb,Tnfsf15,Irf8,Cd274,Golga3,Jarid2,Brd2,Dcun1d3,Stip1,Cdkn1a,Dnajb2,Plat,Gcnt2,Dnajb4,Phf6,Uchl1,Rtn1,Acvr1,Glipr2,Cept1,Stk40,Egr2,Bcl6,Dnaja1,Aoah,Map3k6,Hsph1,Sod2,Sgms2,Jmjd6,Pigv,Bcor |
| 1.141e-02 | -4.47 | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | MSigDB lists | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | 325 | 38 | 15632 | 1249 |
Trip10,Rbbp8,Cd40,Eno1,N4bp1,Klf6,Ccng2,Taf4b,Slc39a4,Tgs1,Col18a1,Atf3,Marcksl1,Clcn5,Slc48a1,Dmwd,Myo1b,Daam1,Ppp1r15a,Slc12a9,Slc7a8,Kctd12,Pde7b,Trip13,Piezo1,Bcorl1,Sap30,Ier3,Gpd2,Traf3ip2,Ripk2,Mmp9,Ptk2,Xkr8,Larp1,Mtdh,Thbs1,Clic4 |
| 1.141e-02 | -4.47 | GO_NEURAL_TUBE_DEVELOPMENT | MSigDB lists | GO_NEURAL_TUBE_DEVELOPMENT | 145 | 20 | 15632 | 1249 |
Rpgrip1l,Sdc4,Sec24b,Notch1,Apaf1,Lhx2,Sema4c,Intu,Hif1a,Tulp3,Phgdh,Ift57,Phactr4,Vasp,Fzd1,Plod3,Mthfd1l,Ptch1,Lmo4,Sema3c |
| 1.141e-02 | -4.47 | NOTCH_DN.V1_DN | MSigDB lists | NOTCH_DN.V1_DN | 145 | 20 | 15632 | 1249 |
Slpi,Gpr68,Sele,Lztfl1,Lrp4,Sp140,Serpine1,Klf2,Tnfrsf8,Plat,Cd82,Tnfsf10,Orai2,Fmnl2,Dio2,Zc3h12a,Dram1,Mmp25,Ddx4,Itga9 |
| 1.142e-02 | -4.47 | lung development | biological process | GO:0030324 | 215 | 24 | 20694 | 1406 |
Klf2,Errfi1,Foxp4,Jmjd6,Slc7a11,Spry2,Sec24b,Plod3,Pdgfrb,Gpsm2,Mmp14,Notch1,Hhex,Hmga2,Sav1,Lif,Tnc,Kdr,Stk40,Lox,Hopx,Pdpn,Timeless,Map2k1 |
| 1.143e-02 | -4.47 | VEGFR2 mediated cell proliferation | REACTOME pathways | R-MMU-5218921 | 222 | 30 | 8608 | 757 |
Jak2,Map2k1,Ppp2r1b,Kdr,Pdgfrb,Ksr1,Il2rg,Src,Ppp2r5a,Irs2,Angpt1,Psme2b,Pdgfb,Spred1,Kitl,Psmb6,Dusp6,Psme1,Sphk1,Dusp5,Rasgrp1,Psmb9,Rapgef2,Psme2,Psma6,Psmd10,Met,Ptk2,Psmb8,Psmb10 |
| 1.148e-02 | -4.47 | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DEGRANULATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DEGRANULATION | 18 | 5 | 15632 | 1249 |
Syk,Adora2b,Fgr,Il4ra,Ptafr |
| 1.148e-02 | -4.47 | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | MSigDB lists | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | 18 | 5 | 15632 | 1249 |
Crkl,Syk,Pik3cd,Lyn,Hck |
| 1.148e-02 | -4.47 | GO_REGULATION_OF_INTERLEUKIN_2_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_2_BIOSYNTHETIC_PROCESS | 18 | 5 | 15632 | 1249 |
Cd86,Il1a,Il1b,Irf4,Cd80 |
| 1.148e-02 | -4.47 | GO_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 18 | 5 | 15632 | 1249 |
Jun,Hif1a,Fos,Stat3,Pdgfb |
| 1.148e-02 | -4.47 | GREENBAUM_E2A_TARGETS_DN | MSigDB lists | GREENBAUM_E2A_TARGETS_DN | 18 | 5 | 15632 | 1249 |
Cd74,Slfn4,Tmem229b,Slfn3,Evl |
| 1.148e-02 | -4.47 | BIOCARTA_TID_PATHWAY | MSigDB lists | BIOCARTA_TID_PATHWAY | 18 | 5 | 15632 | 1249 |
Nfkb1,Tnfrsf1b,Jak2,Tnf,Nfkbia |
| 1.148e-02 | -4.47 | GO_PEPTIDASE_ACTIVATOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | MSigDB lists | GO_PEPTIDASE_ACTIVATOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | 18 | 5 | 15632 | 1249 |
Apaf1,Casp1,Casp3,Nod1,Ctsc |
| 1.148e-02 | -4.47 | GO_REGULATION_OF_IMMUNOGLOBULIN_SECRETION | MSigDB lists | GO_REGULATION_OF_IMMUNOGLOBULIN_SECRETION | 18 | 5 | 15632 | 1249 |
Il6,Tnf,Tnfsf4,Cd40,Traf2 |
| 1.148e-02 | -4.47 | GO_MAST_CELL_MEDIATED_IMMUNITY | MSigDB lists | GO_MAST_CELL_MEDIATED_IMMUNITY | 18 | 5 | 15632 | 1249 |
Serpinb9,Pik3cd,Lyn,Rasgrp1,Nr4a3 |
| 1.148e-02 | -4.47 | HU_ANGIOGENESIS_UP | MSigDB lists | HU_ANGIOGENESIS_UP | 18 | 5 | 15632 | 1249 |
Sipa1l1,Fos,Sema3c,Stxbp1,Rnd3 |
| 1.148e-02 | -4.47 | GO_PROSTANOID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_PROSTANOID_BIOSYNTHETIC_PROCESS | 18 | 5 | 15632 | 1249 |
Cd74,Ptgs2,Ptges,Sphk1,Edn1 |
| 1.148e-02 | -4.47 | GO_REGULATION_OF_HETEROTYPIC_CELL_CELL_ADHESION | MSigDB lists | GO_REGULATION_OF_HETEROTYPIC_CELL_CELL_ADHESION | 18 | 5 | 15632 | 1249 |
Myadm,Gcnt2,Il1rn,Tnf,Il1b |
| 1.148e-02 | -4.47 | GO_PYRIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_PYRIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | 18 | 5 | 15632 | 1249 |
Me1,Kmo,Pnp2,Psat1,Nampt |
| 1.148e-02 | -4.47 | GO_NEGATIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY | 18 | 5 | 15632 | 1249 |
H2-Q4,H2-Q7,H2-Q6,Serpinb9,Tap1 |
| 1.148e-02 | -4.47 | SHIN_B_CELL_LYMPHOMA_CLUSTER_5 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_5 | 18 | 5 | 15632 | 1249 |
Socs3,Il6,Ciita,Tnf,Gfi1 |
| 1.148e-02 | -4.47 | endocardial cushion development | biological process | GO:0003197 | 46 | 8 | 20694 | 1406 |
Acvrl1,Mdm2,Thbs1,Cited2,Bmp2,Acvr1,Jag1,Notch1 |
| 1.151e-02 | -4.46 | Cyclin E associated events during G1/S transition | REACTOME pathways | R-MMU-69202 | 66 | 12 | 8608 | 757 |
Psmb6,Psme1,Ccnd1,Psmb9,Psme2,Psma6,Ccne1,Psmd10,Psme2b,Psmb8,Psmb10,Cdkn1a |
| 1.151e-02 | -4.46 | Cyclin A:Cdk2-associated events at S phase entry | REACTOME pathways | R-MMU-69656 | 66 | 12 | 8608 | 757 |
Psmb9,Psme1,Ccnd1,Psmb6,Psmb10,Cdkn1a,Psmb8,Ccne1,Psmd10,Psme2b,Psme2,Psma6 |
| 1.152e-02 | -4.46 | extrinsic component of membrane | cellular component | GO:0019898 | 309 | 32 | 20747 | 1409 |
Pml,Gng11,Crkl,Cish,Ezr,Snx10,Bcl2l11,Fgr,Src,Psd,Rgs1,Gnb4,Zc3h12a,Socs3,Errfi1,Golga3,Gng12,Hck,Socs1,Pik3r5,Cyth3,Olr1,Gramd1a,Pik3cd,Lyn,Eno1,Bst1,Mitd1,Socs7,Pik3r6,Gng4,Gna15 |
| 1.154e-02 | -4.46 | GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_DN | MSigDB lists | GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_DN | 174 | 23 | 15632 | 1249 |
Rcsd1,Arid5b,Cxcl10,Oas1g,Kif5c,St3gal1,Egr3,Rcl1,Jak2,Cnp,Jarid2,Dgka,Rasgrp1,Oas1a,Rnf19a,Pdlim7,Wdfy1,Csrnp1,Nfkbiz,Sav1,Rsad2,Cers6,Tnc |
| 1.154e-02 | -4.46 | GSE27786_NKCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_NKCELL_VS_MONO_MAC_UP | 174 | 23 | 15632 | 1249 |
Etnk1,Odc1,Phf6,Slfn9,Cldnd1,Cmklr1,Relb,Enpp4,Rcl1,Rnf114,Brd2,Dync1h1,Tap2,Psme2,Bbx,Nmi,Slc39a4,Rab10,Slfn8,Spry2,Dock10,G3bp2,Cox17 |
| 1.154e-02 | -4.46 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN | 174 | 23 | 15632 | 1249 |
Egr1,Upp1,Klf8,Hif1a,Me1,Plod3,Dpy19l1,Tpst1,Tmem184b,Itga5,Slc31a1,Etnk1,Sema4c,Adora2b,Thbs1,Adam19,Gfpt1,Vcam1,Ednrb,Rgl1,Map2k1,Cnn3,Jag1 |
| 1.154e-02 | -4.46 | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_DN | MSigDB lists | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_DN | 174 | 23 | 15632 | 1249 |
Nod1,Il4ra,Etv3,Rffl,Pde1b,Cish,Frmd6,Plat,Ust,Orai2,Nr4a3,Ptgir,Dyrk2,Oas2,Dgka,Kctd12,Rasgrp1,Tmeff1,Akt3,Cd86,Col11a2,Tshz1,Clic5 |
| 1.154e-02 | -4.46 | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN | 174 | 23 | 15632 | 1249 |
Rbms2,Myo10,Tnfaip3,Gbp2,Marcksl1,Pttg1,Tpx2,Nxf1,Tbc1d1,Lrch1,Slc15a3,Phlpp1,Nfkbie,Pde5a,Cenpe,Gtpbp2,Slc37a3,Parp3,Rcsd1,Cnn3,Stx6,Fam72a,Dusp6 |
| 1.159e-02 | -4.46 | MANTOVANI_VIRAL_GPCR_SIGNALING_UP | MSigDB lists | MANTOVANI_VIRAL_GPCR_SIGNALING_UP | 81 | 13 | 15632 | 1249 |
Ppp2r2a,Vcam1,Nfkbiz,Itpkc,C3,Myc,Itgb8,Cp,Prkce,Gpr18,Il10,Flt1,Ccl12 |
| 1.167e-02 | -4.45 | MS4A | interpro domains | IPR030417 | 20 | 5 | 19984 | 1430 |
Ms4a4b,Ms4a6c,Ms4a6b,Ms4a6d,Ms4a4c |
| 1.167e-02 | -4.45 | transcription coactivator activity | molecular function | GO:0003713 | 257 | 28 | 20217 | 1400 |
Med13,Kat2b,Pml,Dr1,Pou3f1,Cited2,Hinfp,Maml2,Ncoa7,Birc2,Mtdh,Hmga1,Nupr1,Nr1h3,Bcl9,Nr3c1,Rap2c,Helz2,Arid5b,Junb,Rbpms,Med21,Jun,Jmjd6,Daxx,Nsd3,Cenpj,Psip1 |
| 1.169e-02 | -4.45 | GO_GLIAL_CELL_MIGRATION | MSigDB lists | GO_GLIAL_CELL_MIGRATION | 32 | 7 | 15632 | 1249 |
Ccl12,P2ry12,Cdk5r1,Tspo,Mmp14,Vcan,Socs7 |
| 1.169e-02 | -4.45 | GO_PROTEIN_DESTABILIZATION | MSigDB lists | GO_PROTEIN_DESTABILIZATION | 32 | 7 | 15632 | 1249 |
Mul1,Src,Rnf139,Mdm2,Sirt1,Trim21,Bmp2 |
| 1.169e-02 | -4.45 | PID_INTEGRIN_A4B1_PATHWAY | MSigDB lists | PID_INTEGRIN_A4B1_PATHWAY | 32 | 7 | 15632 | 1249 |
Src,Itga4,Ptk2,Igsf8,Cd14,Thbs1,Vcam1 |
| 1.169e-02 | -4.45 | PID_SYNDECAN_4_PATHWAY | MSigDB lists | PID_SYNDECAN_4_PATHWAY | 32 | 7 | 15632 | 1249 |
Itga5,Mmp9,Ccl5,Ptk2,Thbs1,Tnc,Sdc4 |
| 1.170e-02 | -4.45 | regulation of immune response to tumor cell | biological process | GO:0002837 | 21 | 5 | 20694 | 1406 |
Pvr,Klrk1,Il12b,Cd274,Nectin2 |
| 1.170e-02 | -4.45 | positive regulation of mast cell degranulation | biological process | GO:0043306 | 21 | 5 | 20694 | 1406 |
Stxbp1,Il4ra,Syk,Fgr,Adora2b |
| 1.170e-02 | -4.45 | response to angiotensin | biological process | GO:1990776 | 21 | 5 | 20694 | 1406 |
Cav1,Nfkb1,Igf1r,Agtrap,Src |
| 1.170e-02 | -4.45 | negative regulation of glucose import | biological process | GO:0046325 | 21 | 5 | 20694 | 1406 |
Myc,Pid1,Rhoq,Tnf,Stxbp3 |
| 1.170e-02 | -4.45 | positive regulation of lymphocyte apoptotic process | biological process | GO:0070230 | 21 | 5 | 20694 | 1406 |
Cd274,Ccl5,Nfkbid,Il10,Myc |
| 1.170e-02 | -4.45 | positive regulation of cell migration involved in sprouting angiogenesis | biological process | GO:0090050 | 21 | 5 | 20694 | 1406 |
Akt3,Plk2,Hmox1,Kdr,Ptgs2 |
| 1.170e-02 | -4.45 | regulation of immunoglobulin secretion | biological process | GO:0051023 | 21 | 5 | 20694 | 1406 |
Il6,Cd40,Traf2,Tnf,Tnfsf4 |
| 1.170e-02 | -4.45 | regulation of interleukin-8 secretion | biological process | GO:2000482 | 21 | 5 | 20694 | 1406 |
Tlr6,Mapkbp1,Cd14,Tlr2,Tlr1 |
| 1.170e-02 | -4.45 | regulation of platelet aggregation | biological process | GO:0090330 | 21 | 5 | 20694 | 1406 |
Pdpn,Lyn,Adrb2,Syk,Ubash3b |
| 1.170e-02 | -4.45 | regulation of mitochondrial depolarization | biological process | GO:0051900 | 21 | 5 | 20694 | 1406 |
Src,Gclc,Kdr,Gclm,Tspo |
| 1.170e-02 | -4.45 | regulation of response to tumor cell | biological process | GO:0002834 | 21 | 5 | 20694 | 1406 |
Nectin2,Cd274,Il12b,Klrk1,Pvr |
| 1.170e-02 | -4.45 | regulation of anoikis | biological process | GO:2000209 | 21 | 5 | 20694 | 1406 |
Src,Notch1,Itga5,Cav1,Ptk2 |
| 1.170e-02 | -4.45 | positive regulation of mast cell activation involved in immune response | biological process | GO:0033008 | 21 | 5 | 20694 | 1406 |
Il4ra,Syk,Adora2b,Fgr,Stxbp1 |
| 1.171e-02 | -4.45 | CHEBOTAEV_GR_TARGETS_DN | MSigDB lists | CHEBOTAEV_GR_TARGETS_DN | 108 | 16 | 15632 | 1249 |
Pla2g4a,Irf4,Rtn2,Dpy19l1,Cnn2,Lrp4,Flrt2,Gbp7,Fam20c,Plat,Ptger4,Ch25h,Palld,Mob3b,Usp18,Il2rg |
| 1.172e-02 | -4.45 | in utero embryonic development | biological process | GO:0001701 | 530 | 50 | 20694 | 1406 |
Lif,Pdgfb,Acvr1b,Hif1a,Mafg,Mgat1,Bcl2l11,Map2k1,Bmp2,Spint2,Ptch1,Itgav,Bcor,Gja1,Chst11,Atp11a,Sbds,Rcn1,Keap1,Adar,Maff,Apba1,Hhex,Notch1,Cited2,Socs3,Inpp5b,Hopx,Slc30a1,Prdm1,Med21,Angpt1,Spic,Acvrl1,Rbbp8,Il10,Phf6,Hinfp,Acvr1,Klf2,Eno1,Vcam1,Edn1,Notch2,Rpgrip1l,Itga4,Plod3,Junb,Pdgfrb,Fzd5 |
| 1.173e-02 | -4.45 | GSE41867_NAIVE_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP | 184 | 24 | 15632 | 1249 |
Pde1b,Cers6,Itpr1,Rbm43,Slamf7,Samhd1,Slc28a2,Cd38,Mxd1,Slc39a13,Plagl1,Oas1a,Ccl5,Pde4b,Casp4,Plekha2,Tap2,Tax1bp1,Oas1g,Ell2,Il18,Parp11,Chic2,Grina |
| 1.173e-02 | -4.45 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_DN | 184 | 24 | 15632 | 1249 |
Rnf34,Mthfr,Spata13,Cish,Ly75,Ctsc,Nqo1,Ccnd1,Ifit2,Tank,Eno1,Swap70,Inpp1,Ccl4,Dek,Dnajb2,Tcea1,Ifit3b,Uba7,Snx2,Gch1,Irf7,Fosb,Ifit3 |
| 1.173e-02 | -4.45 | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_UP | 184 | 24 | 15632 | 1249 |
Phlpp2,Stat4,Slc39a14,Ebi3,Endod1,Kif5c,Odc1,Tnip3,Osbpl3,Bcl2a1a,Cflar,Bcl2a1b,Ppp1r14b,Fut8,Irf4,Stap1,Cox17,Bcl2a1d,Malt1,Marcksl1,Magohb,Tpi1,Ccl22,Rras2 |
| 1.173e-02 | -4.45 | GSE21063_WT_VS_NFATC1_KO_BCELL_DN | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_BCELL_DN | 184 | 24 | 15632 | 1249 |
Golga3,Sirt1,Flnb,Rab10,Spata5l1,Socs7,Nfkb2,Clic4,Asf1a,Znrf1,Jak2,Osbpl3,Gpsm2,Ddhd1,Crbn,Armcx6,Hivep2,Psma6,Cpd,Ifrd1,Tulp3,Nupr1,Marcksl1,Sla |
| 1.173e-02 | -4.45 | GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_DN | MSigDB lists | GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_DN | 184 | 24 | 15632 | 1249 |
Morc3,Ehd1,Msr1,Setdb2,Ppp2r5a,Spry2,Mid1,Scarf1,Chst11,Ifih1,Slco3a1,Cutc,Cd14,Gja1,Rnf14,Jarid2,Asah2,Rapgef2,Ptgir,Dnaja2,Dram1,Tnfaip2,Polr2g,Wdr43 |
| 1.173e-02 | -4.45 | GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDC_UP | 184 | 24 | 15632 | 1249 |
Stx6,Zeb1,Tmeff1,Wdfy1,Jarid2,Brd2,Myadm,Map4k4,Cdkn1a,Adam19,Tnfaip2,Pim1,Gpr85,Nr4a3,Ptger4,Mecp2,Tra2a,Cish,Nfkbia,Aff1,Chmp4b,Gpc1,Nlrp3,Ier2 |
| 1.173e-02 | -4.45 | GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_UP | 184 | 24 | 15632 | 1249 |
Ppfibp2,Dio2,Dusp28,Tgfbi,Isg20,Pdlim7,Lcp2,Fosb,Junb,Slc7a8,Gja1,Crim1,Gbp2,Tnfaip3,Col4a2,F11r,Ier2,Dusp4,Traf2,Jun,Gpsm2,Armcx6,Klf6,Stat5a |
| 1.176e-02 | -4.44 | - | gene3d domains | 3.40.50.1240 | 17 | 5 | 8819 | 755 |
Acp2,Pfkfb3,Minpp1,Acpp,Ubash3b |
| 1.183e-02 | -4.44 | SELECTIN | prints domains | PR00343 | 3 | 2 | 5821 | 374 |
Sele,Sell |
| 1.183e-02 | -4.44 | LEUZIPPRJUN | prints domains | PR00043 | 3 | 2 | 5821 | 374 |
Jun,Junb |
| 1.183e-02 | -4.44 | ATHOOK | prints domains | PR00929 | 3 | 2 | 5821 | 374 |
Hmga2,Hmga1 |
| 1.183e-02 | -4.44 | NUCLEARECPTR | prints domains | PR01284 | 3 | 2 | 5821 | 374 |
Nr4a3,Nr4a1 |
| 1.185e-02 | -4.44 | Notch-HLH transcription pathway | REACTOME pathways | R-MMU-350054 | 11 | 4 | 8608 | 757 |
Notch2,Maml2,Kat2b,Notch1 |
| 1.185e-02 | -4.44 | P2Y receptors | REACTOME pathways | R-MMU-417957 | 11 | 4 | 8608 | 757 |
P2ry13,P2ry2,P2ry12,P2ry14 |
| 1.185e-02 | -4.44 | DEx/H-box helicases activate type I IFN and inflammatory cytokines production | REACTOME pathways | R-MMU-3134963 | 11 | 4 | 8608 | 757 |
Irf7,Nfkb2,Nfkb1,Myd88 |
| 1.185e-02 | -4.44 | actin filament bundle | cellular component | GO:0032432 | 95 | 13 | 20747 | 1409 |
Flnb,Zyx,Dst,Fscn1,Ptk2,Pdlim7,Actb,Micall2,Daam1,Palld,Cnn2,Tpm4,Marcks |
| 1.186e-02 | -4.43 | GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | 64 | 11 | 15632 | 1249 |
Spire1,Cdc42ep4,Icam1,Evl,Nck1,Vasp,Hck,Rictor,Csf3,Prkce,Cdc42ep2 |
| 1.186e-02 | -4.43 | GO_ACTIN_FILAMENT | MSigDB lists | GO_ACTIN_FILAMENT | 64 | 11 | 15632 | 1249 |
Myo1b,Rcsd1,Src,Ezr,Rac3,Palld,Mark2,Gng12,Hck,Keap1,Rhoq |
| 1.186e-02 | -4.43 | GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | 64 | 11 | 15632 | 1249 |
Stat5a,Zc3h12a,Ptgs2,Edn1,Pdgfb,Nrp2,Thbs1,Kdr,Vegfc,Angpt1,Met |
| 1.186e-02 | -4.43 | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM | MSigDB lists | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM | 64 | 11 | 15632 | 1249 |
Cx3cl1,Tpi1,Col18a1,Ldha,Vcam1,Sdc4,Actb,Prdx1,Eno1,Phactr4,Cp |
| 1.186e-02 | -4.43 | Ras signaling pathway | KEGG pathways | mmu04014 | 227 | 31 | 7931 | 713 |
Csf1,Met,Map2k1,Rel,Ikbkg,Pdgfrb,Vegfc,Rasgrp1,Rac3,Rras2,Gng4,Kitl,Pdgfc,Igf1r,Ralgds,Flt1,Gng12,Gnb4,Gng11,Plaat3,Pik3cd,Ets2,Kdr,Ksr1,Rgl1,Nfkb1,Pla2g4a,Angpt1,Pdgfb,Rapgef5,Akt3 |
| 1.187e-02 | -4.43 | regulation of membrane permeability | biological process | GO:0090559 | 65 | 10 | 20694 | 1406 |
Ier3,F11r,Bcl2l11,Stat3,Slc9a1,Bnip3,Hk2,Mul1,Cnp,Pmaip1 |
| 1.187e-02 | -4.43 | GO_POSITIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT | 254 | 31 | 15632 | 1249 |
Slc9a1,Rhou,Hap1,Csf3,Rnf31,Fzd5,Tnfsf14,Cav1,Hcls1,Bambi,Jak2,Il1b,Stard7,Zc3h12a,Tlr3,Tlr9,Il18,Il12b,Tlr2,Cxcl10,Ptgs2,Il6,Micall2,Rab21,Mdm2,Rbpms,Ezr,Tnf,Plagl2,Sphk1,Ddx58 |
| 1.189e-02 | -4.43 | GO_REGULATION_OF_CELL_CYCLE_PROCESS | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE_PROCESS | 506 | 55 | 15632 | 1249 |
Hspa2,Psma6,Ccnd1,Mdm2,Ankrd17,Psmb9,Dusp1,Pbx1,Crlf3,Psmb10,Il1a,Pml,Lif,Ube2e1,Plk3,Psme1,Gpr132,Pdgfb,Btg2,Osm,Pdgfrb,Plk2,Il1b,Pkp4,Pim1,Parp3,Smc5,Psmb6,Prdm9,Cnot4,Prkce,Pdpn,Edn1,Psmd10,Cenpe,Tnks1bp1,Atp2b4,Chmp4b,Cdk5r1,Tpx2,Phip,Pttg1,Plagl1,Nek6,Casp2,Ube2e2,Psme2,Cenpj,Pid1,Atm,Psmb8,Dach1,Cdkn1a,Tmem67,Tmod3 |
| 1.192e-02 | -4.43 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_8 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_8 | 12 | 4 | 15632 | 1249 |
Syk,Tal2,Nr4a3,Ptch1 |
| 1.192e-02 | -4.43 | MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_DN | MSigDB lists | MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_DN | 12 | 4 | 15632 | 1249 |
Mdfic,Ptch1,Kat2b,Rab9 |
| 1.192e-02 | -4.43 | WU_HBX_TARGETS_2_DN | MSigDB lists | WU_HBX_TARGETS_2_DN | 12 | 4 | 15632 | 1249 |
Klf6,Eif2ak2,Il6,Acp2 |
| 1.192e-02 | -4.43 | GO_CELLULAR_RESPONSE_TO_CHOLESTEROL | MSigDB lists | GO_CELLULAR_RESPONSE_TO_CHOLESTEROL | 12 | 4 | 15632 | 1249 |
Hmgcs1,Lrp8,Inhba,Ptch1 |
| 1.192e-02 | -4.43 | TAGHAVI_NEOPLASTIC_TRANSFORMATION | MSigDB lists | TAGHAVI_NEOPLASTIC_TRANSFORMATION | 12 | 4 | 15632 | 1249 |
Fosb,Pdgfb,Nek6,Agrn |
| 1.192e-02 | -4.43 | GO_REGULATION_OF_VITAMIN_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_VITAMIN_METABOLIC_PROCESS | 12 | 4 | 15632 | 1249 |
Gfi1,Il1b,Nfkb1,Tnf |
| 1.192e-02 | -4.43 | REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON | MSigDB lists | REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON | 12 | 4 | 15632 | 1249 |
Cd14,Ikbke,Tlr3,Irf7 |
| 1.192e-02 | -4.43 | BIOCARTA_FIBRINOLYSIS_PATHWAY | MSigDB lists | BIOCARTA_FIBRINOLYSIS_PATHWAY | 12 | 4 | 15632 | 1249 |
Serpine1,Plat,Serpinb2,Plau |
| 1.192e-02 | -4.43 | GO_GLUCOSE_BINDING | MSigDB lists | GO_GLUCOSE_BINDING | 12 | 4 | 15632 | 1249 |
Hk1,Gys1,Hk2,Hk3 |
| 1.192e-02 | -4.43 | GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | 12 | 4 | 15632 | 1249 |
Bcl6,Il4ra,Hlx,Tnfsf4 |
| 1.192e-02 | -4.43 | GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_INVOLVED_IN_INFLAMMATORY_RESPONSE | MSigDB lists | GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_INVOLVED_IN_INFLAMMATORY_RESPONSE | 12 | 4 | 15632 | 1249 |
Il4ra,Slc7a2,Lyn,Syk |
| 1.192e-02 | -4.43 | GO_REGULATION_OF_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS | 12 | 4 | 15632 | 1249 |
Htr2b,Fabp3,Htr2a,Pdgfb |
| 1.192e-02 | -4.43 | BIOCARTA_IL17_PATHWAY | MSigDB lists | BIOCARTA_IL17_PATHWAY | 12 | 4 | 15632 | 1249 |
Il6,Kitl,Cd34,Csf3 |
| 1.192e-02 | -4.43 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_VIA_MHC_CLASS_IB | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_VIA_MHC_CLASS_IB | 12 | 4 | 15632 | 1249 |
Ap3b1,Tap2,Tap1,Abcb1a |
| 1.192e-02 | -4.43 | GO_LEUKOCYTE_ADHESION_TO_VASCULAR_ENDOTHELIAL_CELL | MSigDB lists | GO_LEUKOCYTE_ADHESION_TO_VASCULAR_ENDOTHELIAL_CELL | 12 | 4 | 15632 | 1249 |
Tnf,Itga4,Vcam1,Sele |
| 1.192e-02 | -4.43 | GO_JAK_STAT_CASCADE_INVOLVED_IN_GROWTH_HORMONE_SIGNALING_PATHWAY | MSigDB lists | GO_JAK_STAT_CASCADE_INVOLVED_IN_GROWTH_HORMONE_SIGNALING_PATHWAY | 12 | 4 | 15632 | 1249 |
Stat3,Stat5a,Jak2,Lyn |
| 1.192e-02 | -4.43 | REACTOME_P75NTR_SIGNALS_VIA_NFKB | MSigDB lists | REACTOME_P75NTR_SIGNALS_VIA_NFKB | 12 | 4 | 15632 | 1249 |
Myd88,Nfkbia,Sqstm1,Ripk2 |
| 1.192e-02 | -4.43 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | MSigDB lists | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | 12 | 4 | 15632 | 1249 |
Casp8,Casp7,Casp3,Dbnl |
| 1.192e-02 | -4.43 | ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_UP | MSigDB lists | ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_UP | 12 | 4 | 15632 | 1249 |
Rras2,Samsn1,Ift57,Vrk2 |
| 1.192e-02 | -4.43 | GO_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN | MSigDB lists | GO_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN | 12 | 4 | 15632 | 1249 |
Tap2,Tapbpl,Tap1,Abcb1a |
| 1.192e-02 | -4.43 | GO_REGULATION_OF_MHC_CLASS_II_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_MHC_CLASS_II_BIOSYNTHETIC_PROCESS | 12 | 4 | 15632 | 1249 |
Pf4,Il10,Sirt1,Ciita |
| 1.192e-02 | -4.43 | HASINA_NOL7_TARGETS_UP | MSigDB lists | HASINA_NOL7_TARGETS_UP | 12 | 4 | 15632 | 1249 |
Rtn1,Hif1a,Timp1,Plaur |
| 1.195e-02 | -4.43 | regulation of B cell apoptotic process | biological process | GO:0002902 | 29 | 6 | 20694 | 1406 |
Il10,Irs2,Cd74,Lyn,Bcl2a1a,Myc |
| 1.195e-02 | -4.43 | regulation of ruffle assembly | biological process | GO:1900027 | 29 | 6 | 20694 | 1406 |
Stap1,Cyfip1,Evl,Icam1,Cav1,P2ry12 |
| 1.195e-02 | -4.43 | zinc ion transport | biological process | GO:0006829 | 29 | 6 | 20694 | 1406 |
Ap3b1,Slc39a4,Slc39a14,Slc39a13,Slc30a4,Slc30a1 |
| 1.197e-02 | -4.43 | Interleukin-3, 5 and GM-CSF signaling | REACTOME pathways | R-MMU-512988 | 232 | 31 | 8608 | 757 |
Pdgfb,Spred1,Kitl,Src,Ppp2r5a,Irs2,Angpt1,Psme2b,Pdgfrb,Ksr1,Il2rg,Jak2,Map2k1,Ppp2r1b,Met,Ptk2,Psmb8,Psmb10,Psme2,Psma6,Psmd10,Rasgrp1,Psmb9,Rapgef2,Pik3cd,Stat5a,Crkl,Psmb6,Dusp6,Psme1,Dusp5 |
| 1.199e-02 | -4.42 | GO_CELL_CYCLE_PHASE_TRANSITION | MSigDB lists | GO_CELL_CYCLE_PHASE_TRANSITION | 234 | 29 | 15632 | 1249 |
Cenpj,Plk2,Ccne1,Tuba4a,Rhou,Inhba,Phlda1,Timeless,Gpr132,Mcm6,Acvr1b,Pim2,Prkar2b,Ppp2r2a,Gfi1,Cdkn1a,Rbbp8,Dync1h1,Optn,Ccnd1,Acvr1,Abcb1a,Tpx2,Cdkn2d,Mcm10,Plk3,Chmp4b,Crlf3,Hinfp |
| 1.199e-02 | -4.42 | FCH | pfam domains | PF00611 | 20 | 5 | 18711 | 1348 |
Fcho2,Pstpip2,Trip10,Fnbp1l,Fchsd2 |
| 1.200e-02 | -4.42 | FISCHER_G2_M_CELL_CYCLE | MSigDB lists | FISCHER_G2_M_CELL_CYCLE | 214 | 27 | 15632 | 1249 |
Stat1,Cdc42ep4,Rsbn1,Dr1,Cflar,Ldlr,Tnfaip2,Birc3,Cep350,Sap30,Trip13,Cdkn2d,Dcp2,Pttg1,Tpx2,Sertad3,Arl4a,Plau,Bmp2,Rgs3,Cenpe,Plekha5,Gpsm2,Katna1,Rin2,Mid1,Dusp4 |
| 1.200e-02 | -4.42 | BENPORATH_MYC_TARGETS_WITH_EBOX | MSigDB lists | BENPORATH_MYC_TARGETS_WITH_EBOX | 214 | 27 | 15632 | 1249 |
Tnfrsf8,Hif1a,Icam1,Ccnd2,Irf2,Mthfr,Mdm2,Ccnd1,Pla2g4a,Eno1,Jun,Ets2,Sqstm1,Srm,Actb,Arf4,Egr3,Dck,Pim2,Sirt1,Met,Isg20,Ampd3,Serpine1,Casp8,Txn1,Junb |
| 1.202e-02 | -4.42 | Platelet activation, signaling and aggregation | REACTOME pathways | R-MMU-76002 | 260 | 34 | 8608 | 757 |
Rasgrp1,Serpine1,Timp1,Pik3cd,Itpr1,Pcdh7,Lcp2,Srgn,Dgkh,Serpina3f,Ptk2,Pik3r5,Abcc4,Gna15,Plek,Prkce,P2ry12,Vegfc,Pf4,Il2rg,Dgka,Jak2,Endod1,Syk,Pdpn,Pdgfb,Thbs1,Pik3r6,Pla2g4a,Tuba4a,Gtpbp2,Stxbp3,Src,Lyn |
| 1.202e-02 | -4.42 | Glycolysis / Gluconeogenesis | KEGG pathways | ko00010 | 65 | 12 | 7931 | 713 |
Minpp1,Aldh1b1,Ldha,Hk2,Eno2,Hk1,Pgm1,Eno1,Pgk1,Tpi1,Pfkl,Hk3 |
| 1.202e-02 | -4.42 | Glycolysis / Gluconeogenesis | KEGG pathways | mmu00010 | 65 | 12 | 7931 | 713 |
Ldha,Minpp1,Aldh1b1,Eno2,Hk2,Hk1,Pfkl,Tpi1,Pgk1,Hk3,Pgm1,Eno1 |
| 1.204e-02 | -4.42 | phosphatase binding | molecular function | GO:0019902 | 212 | 24 | 20217 | 1400 |
Ap3b1,Ctsc,Stau1,Vcan,Slc9a1,Sphk1,Ppp6r1,Adrb2,Stat3,Cpd,Phactr4,Syk,Spred1,Itpr1,Stat1,Smg7,Ppp2r2a,Ppp1r15a,Met,Irs2,Mvp,Traf2,Ptk2,Atp2b4 |
| 1.208e-02 | -4.42 | CTACTGT_MIR199A | MSigDB lists | CTACTGT_MIR199A | 165 | 22 | 15632 | 1249 |
Snn,Dcbld2,Bmp2,Phf6,Calcrl,Tab2,Rnf139,Atf3,Cpeb4,Naa25,Met,Vcan,Aebp2,Phlpp2,Itgb8,Zeb1,Nrp2,Akt3,Map2k1,Cited2,Plod2,Fos |
| 1.208e-02 | -4.42 | GSE22886_TH1_VS_TH2_12H_ACT_DN | MSigDB lists | GSE22886_TH1_VS_TH2_12H_ACT_DN | 165 | 22 | 15632 | 1249 |
Spint2,Rnf19a,Arhgap26,Slc39a14,Slpi,Ksr1,Gpr132,Pla2g4a,Cep350,Itpr1,Snx10,Acp2,Me1,Cd164,Dio2,Cdc42ep2,Jak2,Siglece,Arg2,Cxcl10,Trim13,Lif |
| 1.209e-02 | -4.42 | Ubiquitin-dependent degradation of Cyclin D | REACTOME pathways | R-MMU-75815 | 51 | 10 | 8608 | 757 |
Psmb10,Psmb9,Psmb8,Ccnd1,Psme2b,Psme1,Psmd10,Psma6,Psme2,Psmb6 |
| 1.209e-02 | -4.42 | Ubiquitin-dependent degradation of Cyclin D1 | REACTOME pathways | R-MMU-69229 | 51 | 10 | 8608 | 757 |
Psmb9,Psmb8,Psmb10,Psma6,Psmb6,Psme2,Ccnd1,Psme2b,Psmd10,Psme1 |
| 1.210e-02 | -4.41 | regulation of tissue remodeling | biological process | GO:0034103 | 85 | 12 | 20694 | 1406 |
Il6,Syk,Ubash3b,Klf6,Ptger4,Gja1,Itgav,Abr,Cd38,Fcgr4,Il18,Pml |
| 1.210e-02 | -4.41 | response to corticosteroid | biological process | GO:0031960 | 85 | 12 | 20694 | 1406 |
Jak2,Zfp36,Il6,Nr3c1,Tnf,Il1rn,Ddit4,Ass1,Map2k1,Fas,Ifnb1,Il10 |
| 1.212e-02 | -4.41 | GO_VESICLE_MEMBRANE | MSigDB lists | GO_VESICLE_MEMBRANE | 485 | 53 | 15632 | 1249 |
Scarf1,Ap3b1,Aftph,Irgm2,Msr1,Rab32,H2-Q4,Fcgr1,Pikfyve,Dmxl2,Tlr6,Nck1,Ptch1,Marco,Cav1,Lnpep,Ap3m2,Ldlr,Whamm,Znrf1,Tmem67,Rab20,Tlr2,Sema4c,Mdm2,Rab11fip1,Dbnl,Rab9,Rhoq,Rab21,Itpr1,H2-Q6,Acpp,Traf2,Agtrap,Cd74,H2-Q7,Tlr1,H2-Aa,Inpp5b,Rab10,Fzd5,Gja1,H2-Eb1,Abcc4,Sec24b,Il15ra,Sec24a,Clic4,Pcdh7,Spire1,Fndc3a,H2-Ab1 |
| 1.212e-02 | -4.41 | urogenital system development | biological process | GO:0001655 | 322 | 33 | 20694 | 1406 |
Vcan,Arg2,Tnc,Pdgfb,Cited2,Jag1,Stat5a,Lrp4,Bcl2l11,Angpt1,Timeless,Plaur,Acvr1,Bmp2,Odc1,Gsta3,Ptch1,Stat1,Igf1r,Crkl,Ahr,Pbx1,Egr1,Jmjd6,Notch2,Pdgfrb,Arid5b,Myc,Tiparp,Rpgrip1l,Notch1,Prkx,Tet2 |
| 1.215e-02 | -4.41 | regulation of cellular localization | biological process | GO:0060341 | 955 | 83 | 20694 | 1406 |
Prnp,Fbxo4,Src,Hsph1,Map4k4,Gpr68,Cacnb3,Hcls1,Map2k1,Adora2b,Hap1,Ccne1,Cxcl10,Hif1a,Cyfip1,Lif,Gpc1,Gbp4,Ptgs2,Parp9,Lrp4,Zc3h12a,Ier3,Apba1,Sirt1,Rnf139,Mdm2,Pim3,Pid1,Pmaip1,Gpsm2,Rims3,Sphk1,Uaca,Sqstm1,Crkl,Prkce,Cdk5r1,Hmox1,Hmgn3,Lyn,Cav1,Klf7,Ppp2r5a,Slc7a11,Il4ra,Ccl2,Angpt1,Adrb2,Slc30a1,Ezr,Rab21,Pml,Stxbp1,Lztfl1,Mecp2,Ubash3b,Ptger4,Pde3b,Syk,Plk3,Tnf,Cx3cl1,Adora2a,P2ry2,Mdfic,Cacna1d,Ehd1,Actb,Zfp36,Sec24b,Dtx3l,Htr2a,Txn1,Kmo,Mmp14,Stx6,Dync1h1,Rhoq,Nlgn2,Fgr,Dnaja1,Rabgef1 |
| 1.215e-02 | -4.41 | tissue homeostasis | biological process | GO:0001894 | 182 | 21 | 20694 | 1406 |
Snx10,Akt3,Notch1,Slc28a2,Rac3,Chmp4b,Pla2g4a,Tlr9,Adrb2,Cd34,Vps54,Src,Gcnt2,Acp5,Pdgfrb,Nod2,Csf1,Col11a2,Homer1,Kdr,Prdx5 |
| 1.215e-02 | -4.41 | GO_REGULATION_OF_MRNA_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_MRNA_CATABOLIC_PROCESS | 25 | 6 | 15632 | 1249 |
Pnpt1,Zc3h12a,Zfp36,Polr2g,Btg2,Zc3hav1 |
| 1.215e-02 | -4.41 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | MSigDB lists | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | 25 | 6 | 15632 | 1249 |
Vcan,Sdc2,Sdc4,Gpc1,Sdc1,Agrn |
| 1.215e-02 | -4.41 | LU_TUMOR_VASCULATURE_UP | MSigDB lists | LU_TUMOR_VASCULATURE_UP | 25 | 6 | 15632 | 1249 |
Mmp9,Lcp2,Vcan,Hopx,Isg15,Adap2 |
| 1.215e-02 | -4.41 | VERRECCHIA_RESPONSE_TO_TGFB1_C2 | MSigDB lists | VERRECCHIA_RESPONSE_TO_TGFB1_C2 | 25 | 6 | 15632 | 1249 |
Marcksl1,Cd82,Mmp14,Icam1,Timp1,Rhoc |
| 1.215e-02 | -4.41 | RODRIGUES_NTN1_AND_DCC_TARGETS | MSigDB lists | RODRIGUES_NTN1_AND_DCC_TARGETS | 25 | 6 | 15632 | 1249 |
Arhgef3,Fos,Mmd,Ets2,Nfkbiz,Egr1 |
| 1.215e-02 | -4.41 | GO_VASODILATION | MSigDB lists | GO_VASODILATION | 25 | 6 | 15632 | 1249 |
Adrb2,Adora2b,Sod2,Plod3,Ednrb,Gch1 |
| 1.215e-02 | -4.41 | GO_REGULATION_OF_MEMBRANE_REPOLARIZATION | MSigDB lists | GO_REGULATION_OF_MEMBRANE_REPOLARIZATION | 25 | 6 | 15632 | 1249 |
Kcnj2,Cacna1d,Scn1b,Gja1,Cacnb3,Cav1 |
| 1.215e-02 | -4.41 | WIKMAN_ASBESTOS_LUNG_CANCER_DN | MSigDB lists | WIKMAN_ASBESTOS_LUNG_CANCER_DN | 25 | 6 | 15632 | 1249 |
Ms4a6d,Cd86,Itga4,Atm,Fgl2,Glrx |
| 1.215e-02 | -4.41 | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | 25 | 6 | 15632 | 1249 |
Ppp1r15a,Ptpn2,Nck1,Bfar,Bcl2l11,Ppp1r15b |
| 1.215e-02 | -4.41 | GO_NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 25 | 6 | 15632 | 1249 |
Cd74,Mdm2,Psmd10,Sirt1,Rffl,Rnf34 |
| 1.215e-02 | -4.41 | COLLER_MYC_TARGETS_UP | MSigDB lists | COLLER_MYC_TARGETS_UP | 25 | 6 | 15632 | 1249 |
Slc16a1,Ccnd2,Odc1,Ak4,Nampt,Ass1 |
| 1.215e-02 | -4.41 | GO_CYCLIN_DEPENDENT_PROTEIN_SERINE_THREONINE_KINASE_REGULATOR_ACTIVITY | MSigDB lists | GO_CYCLIN_DEPENDENT_PROTEIN_SERINE_THREONINE_KINASE_REGULATOR_ACTIVITY | 25 | 6 | 15632 | 1249 |
Kat2b,Ccnd1,Cdkn1a,Casp3,Cdkn2d,Ccne1 |
| 1.215e-02 | -4.41 | GO_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | 25 | 6 | 15632 | 1249 |
Thbs1,Stat5a,Pdgfb,Angpt1,Ptgs2,Vegfc |
| 1.217e-02 | -4.41 | Butyrophylin_SPRY | interpro domains | IPR003879 | 53 | 9 | 19984 | 1430 |
Trim30d,Trim12c,Mid1,Rnf135,Trim14,Trim30a,Trim26,Trim21,Trim34a |
| 1.217e-02 | -4.41 | TSENG_IRS1_TARGETS_DN | MSigDB lists | TSENG_IRS1_TARGETS_DN | 127 | 18 | 15632 | 1249 |
Casp2,Tapbp,Rsad2,Mmp14,Carhsp1,Rab9,Cd40,Itpr1,Gja1,Glrx,Frmd6,Tle3,Col4a2,Tgfbi,Lpar1,Traf3ip2,Pml,Hlx |
| 1.223e-02 | -4.40 | invadopodium | cellular component | GO:0071437 | 14 | 4 | 20747 | 1409 |
Pdpn,Nox1,Ezr,Fscn1 |
| 1.224e-02 | -4.40 | regulation of prostaglandin secretion | biological process | GO:0032306 | 14 | 4 | 20694 | 1406 |
Il1a,P2ry2,Edn1,Il1b |
| 1.224e-02 | -4.40 | positive regulation of renal sodium excretion | biological process | GO:0035815 | 14 | 4 | 20694 | 1406 |
Ptger4,Edn1,Ednrb,Adora2a |
| 1.224e-02 | -4.40 | positive regulation of regulatory T cell differentiation | biological process | GO:0045591 | 14 | 4 | 20694 | 1406 |
Il2rg,Bcl6,Lgals9,Socs1 |
| 1.224e-02 | -4.40 | regulation of miRNA metabolic process | biological process | GO:2000628 | 14 | 4 | 20694 | 1406 |
Zc3h12a,Pnpt1,Tent2,Nfkb1 |
| 1.224e-02 | -4.40 | negative regulation of platelet-derived growth factor receptor signaling pathway | biological process | GO:0010642 | 14 | 4 | 20694 | 1406 |
Ptprj,Ptpn2,Ptgir,Glrx |
| 1.224e-02 | -4.40 | neutrophil homeostasis | biological process | GO:0001780 | 14 | 4 | 20694 | 1406 |
Hcar2,Il6,Pde4b,Axl |
| 1.224e-02 | -4.40 | positive regulation of mitochondrial fission | biological process | GO:0090141 | 14 | 4 | 20694 | 1406 |
Ddhd1,Mul1,Bnip3,Kdr |
| 1.224e-02 | -4.40 | negative regulation of alcohol biosynthetic process | biological process | GO:1902931 | 14 | 4 | 20694 | 1406 |
Plek,Bmp2,Nfkb1,Gfi1 |
| 1.224e-02 | -4.40 | positive regulation of vascular endothelial growth factor receptor signaling pathway | biological process | GO:0030949 | 14 | 4 | 20694 | 1406 |
Flt1,Kdr,Angpt1,Hif1a |
| 1.224e-02 | -4.40 | regulation of translation in response to stress | biological process | GO:0043555 | 14 | 4 | 20694 | 1406 |
Ppp1r15a,Eif2ak2,Nck1,Pml |
| 1.224e-02 | -4.40 | regulation of type B pancreatic cell proliferation | biological process | GO:0061469 | 14 | 4 | 20694 | 1406 |
Errfi1,Nr4a3,Nupr1,Nr4a1 |
| 1.224e-02 | -4.40 | positive regulation of podosome assembly | biological process | GO:0071803 | 14 | 4 | 20694 | 1406 |
Tnf,Src,Palld,Fscn1 |
| 1.224e-02 | -4.40 | regulation of nuclear-transcribed mRNA poly(A) tail shortening | biological process | GO:0060211 | 14 | 4 | 20694 | 1406 |
Zfp36,Polr2g,Tent4a,Btg2 |
| 1.224e-02 | -4.40 | positive regulation of gonad development | biological process | GO:1905941 | 14 | 4 | 20694 | 1406 |
Abcb1a,Cited2,Ptger4,Src |
| 1.224e-02 | -4.40 | nitric oxide metabolic process | biological process | GO:0046209 | 14 | 4 | 20694 | 1406 |
Slc7a2,Nos2,Tlr6,Tlr2 |
| 1.224e-02 | -4.40 | negative regulation of vascular permeability | biological process | GO:0043116 | 14 | 4 | 20694 | 1406 |
Ptprj,Angpt1,Adora2a,Nr3c1 |
| 1.224e-02 | -4.40 | B cell apoptotic process | biological process | GO:0001783 | 14 | 4 | 20694 | 1406 |
Myc,Crkl,Traf3ip2,Bcl2l11 |
| 1.226e-02 | -4.40 | regulation of generation of precursor metabolites and energy | biological process | GO:0043467 | 127 | 16 | 20694 | 1406 |
Ddit4,Stat3,Dyrk2,Ier3,Htr2a,Cox17,Myc,Bnip3,Rubcnl,Pnpt1,Nupr1,Irs2,Pgk1,Hif1a,Gfpt1,Ak4 |
| 1.226e-02 | -4.40 | GSE21927_BALBC_VS_C57BL6_MONOCYTE_SPLEEN_DN | MSigDB lists | GSE21927_BALBC_VS_C57BL6_MONOCYTE_SPLEEN_DN | 146 | 20 | 15632 | 1249 |
Itgav,Ifi213,Hivep2,Snx10,Ifi205,Jun,Mndal,Ifi209,Pid1,Il6,Ifi208,Ifi211,Ifi203,Nfkbil1,Ifi214,Aida,Ifi204,Fcho2,Irak2,Ifi207 |
| 1.227e-02 | -4.40 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | 561 | 60 | 15632 | 1249 |
Bcl2a1d,Ccnd1,Mecp2,Cd302,Cd40,Psmb9,Dpy19l1,Mdfic,Crim1,Psmb10,Isg15,Icam1,Usp18,Mcm10,Hhex,Hk2,Fzd1,Slc25a12,Antxr1,Pdgfb,Serpine1,Rrs1,Rnaset2a,Hopx,Plk2,Pkp4,Thbs1,Bcl2a1a,Acsl5,Plcl2,Osbpl3,Pcdh7,Slc43a3,Tgfbi,Vcan,Sdc2,Edn1,Ctsc,Tagln,Ccl12,Bcl2a1b,Cnn2,Plau,Col4a2,Extl2,Aldh1b1,Nlrp3,Lrp8,Jag1,Pdss1,Trim14,Ccne1,Tor3a,Ap3m2,Rnaset2b,Cflar,Adrb2,Mppe1,Il13ra1,Endod1 |
| 1.227e-02 | -4.40 | MODULE_8 | MSigDB lists | MODULE_8 | 400 | 45 | 15632 | 1249 |
Birc2,Pnp2,Nupr1,Lif,Ube2e1,Crim1,Stau1,Atp6v1d,Myo1b,Tor1aip1,Asns,Lad1,Gch1,Dusp6,Map4k4,Gja1,Gdf15,Junb,Slc7a5,Mcm6,Tgfbi,Bambi,Zyx,Tspan3,Cpd,Myc,Ctsc,Arl4a,Tpx2,Il4ra,Sdc1,Pttg1,Ahr,Rnd3,Plod2,Cav1,Eef1e1,Hat1,Mmd,Trip13,Cnn3,Ier3,Rcn1,Filip1l,Ldlr |
| 1.228e-02 | -4.40 | BRUINS_UVC_RESPONSE_LATE | MSigDB lists | BRUINS_UVC_RESPONSE_LATE | 1028 | 102 | 15632 | 1249 |
Jak2,Rbms1,Ldlr,Idi1,Mthfd2,Rab20,Trim21,Usp12,Tmem176a,Mfap3l,Cav1,Sik3,Casp8,Col4a2,Il15,Slc48a1,Ahr,Pikfyve,Gclm,Ggct,Plac8,Sqstm1,Cited2,Ikbke,Slc31a1,Pcgf5,Rab10,Ext1,Car13,Mmp13,Vasn,Pde4b,Csrp1,Atp6v1d,Cd38,Lrch3,Tnc,Ntng2,Tcf4,Tpst1,Cd302,Bcl6,Actb,Tmem123,Tnip1,Esd,Ifi35,Etnk1,Endod1,Dck,Dyrk2,Rcn1,Adrb2,Plscr1,Hat1,Psat1,Ccne1,Rnf31,P4ha1,Pfkfb3,Gng11,Prnp,Sgms2,Nkiras1,Pttg1,Ccnd2,Sass6,Abcb1a,Slc44a1,Cxcl14,Flt1,Agrn,Psmd10,Osbpl3,Vegfc,Dcbld2,Cd55,Herc6,Smc5,Tgfbi,Serpinb9,Lox,Nmi,Dgka,Slc4a7,4930523C07Rik,Gch1,Magohb,St3gal6,Slco3a1,Tbc1d1,Ccdc86,Dbnl,Tapbp,Mlkl,Apobec3,Insl6,Ctu1,Ttc39c,Swap70,Cd40,Tank |
| 1.231e-02 | -4.40 | PROTEIN_KINASE_DOM | prosite domains | PS50011 | 486 | 52 | 13278 | 1037 |
Pim3,Src,Prag1,Flt1,Acvr1b,Map4k4,Dyrk2,Map2k4,Map3k8,Kdr,Fgr,Irak3,Irak2,Plk2,Acvr1,Nek6,Ripk2,Map2k1,Akt3,Ripk3,Stk40,Mlkl,Scyl2,Igf1r,Sgk3,Mapkapk2,Plk3,Lyn,Grk3,Tyk2,Trib1,Jak2,Eif2ak2,Tlk2,Ptk2,Pdgfrb,Mark2,Prkce,Pim1,Pim2,Prkx,Hck,Axl,Ksr1,Ikbke,Met,Vrk2,Syk,Map3k6,Trib3,Acvrl1,Sik3 |
| 1.231e-02 | -4.40 | negative regulation of ion transport | biological process | GO:0043271 | 171 | 20 | 20694 | 1406 |
Agrn,Il1rn,Il1b,Gem,Stoml1,Gpr35,Mmp9,Thbs1,Tlr9,Slc30a1,Htr2a,Cacnb3,Ptgs2,Tnf,Ahr,Icam1,Prkce,Cav1,Irs2,Crbn |
| 1.232e-02 | -4.40 | mouse chr4|4 D2.3 | chromosome location | mouse chr4|4 D2.3 | 42 | 7 | 24173 | 1464 |
Themis2,Xkr8,Map3k6,Pigv,Tmem200b,Phactr4,Smpdl3b |
| 1.232e-02 | -4.40 | TGASTMAGC_NFE2_01 | MSigDB lists | TGASTMAGC_NFE2_01 | 175 | 23 | 15632 | 1249 |
Bnip3,Il6,Mdm2,Gadd45g,Dync1h1,Flt1,Sqstm1,Ass1,Eno1,Etv5,Myo10,Prdm1,Akt3,Procr,Il18rap,Vasp,Snx10,Tuba4a,Map2k1,Sh3bgrl2,Mmp9,Dtx2,Itpkc |
| 1.232e-02 | -4.40 | GSE28408_LY6G_POS_VS_NEG_DC_UP | MSigDB lists | GSE28408_LY6G_POS_VS_NEG_DC_UP | 175 | 23 | 15632 | 1249 |
Tnfaip3,Pbx1,Nxf1,Icam1,Plk3,Cers6,Kdm5b,Ly75,Sat1,Kcnj2,Bcl6,Sp110,Rgs1,Osbpl3,Sema4a,Ptger4,Tyk2,G3bp2,Rapgef2,Snx2,Pstpip2,Ascc3,Gna15 |
| 1.232e-02 | -4.40 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_UP | 175 | 23 | 15632 | 1249 |
Gbp2,Sla,Plau,Aldh1b1,Pcx,Gadd45g,Sdc2,D1Ertd622e,Srm,Syk,Gadd45b,Flt1,Ehd1,Ifit1bl1,Kdr,Kcna3,Odc1,Rnf19b,Flnb,Reps1,Rel,Plk2,Ifit1bl2 |
| 1.232e-02 | -4.40 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN | 175 | 23 | 15632 | 1249 |
Batf,Pkp4,Ldha,Cd55,Serpinb9,Mcm6,Cdk5r1,Trib3,Adora2b,Slc43a3,Ccnd2,Il6,Pdss1,Spen,Eef1e1,Cebpd,Cd69,Wars,Tnfrsf1b,Ppp1r15b,Mthfd1l,Klf6,Ets2 |
| 1.232e-02 | -4.40 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_DN | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_DN | 175 | 23 | 15632 | 1249 |
Ifi214,Kat2b,Hhex,Aff1,Ifi207,Ifi205,Ifi209,Arhgef3,Dhrs9,Ifi213,Ifit2,Parp8,Ifit1bl1,Cenpe,Ifi204,Oas1g,Prkx,Mndal,Ifit1bl2,Ifi203,Oas1a,Ifi208,Ifi211 |
| 1.237e-02 | -4.39 | sensory system development | biological process | GO:0048880 | 383 | 38 | 20694 | 1406 |
Tsku,Gja1,Tdrd7,Clic4,Rcn1,Ahr,Jmjd6,Zhx2,Notch2,Inhba,Fzd5,Slc4a7,Pdgfrb,Rpgrip1l,Ppp2r3a,Zeb1,C3,Casz1,Hif1a,Flt1,Kdr,Tulp3,Phactr4,Pdgfb,Lif,Cited2,Slc25a25,Jag1,Gpd2,P2ry12,Jun,Ikzf1,Stat3,Acvrl1,Prdm1,Lhx2,Hdac1,Zfp513 |
| 1.237e-02 | -4.39 | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | MSigDB lists | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | 56 | 10 | 15632 | 1249 |
Jun,Ass1,Ppp1r14b,Mmd,Prkar2b,Met,Tnfaip3,Tmeff1,Peli1,Carhsp1 |
| 1.237e-02 | -4.39 | BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP | MSigDB lists | BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP | 56 | 10 | 15632 | 1249 |
Maff,Xaf1,Ccdc25,Ccnd1,Sgcb,Notch2,Mpp7,Rcan1,Acpp,Rab32 |
| 1.249e-02 | -4.38 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 | MSigDB lists | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 | 40 | 8 | 15632 | 1249 |
Cdkn1a,Trp53i11,Bnip3,Isg20,Csf1,Plat,Tnf,Uchl1 |
| 1.249e-02 | -4.38 | JIANG_AGING_HYPOTHALAMUS_UP | MSigDB lists | JIANG_AGING_HYPOTHALAMUS_UP | 40 | 8 | 15632 | 1249 |
Map2k1,Itpr1,Hk1,Ppa1,Psma6,Snx2,Prdx1,Actb |
| 1.249e-02 | -4.38 | GO_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS | 40 | 8 | 15632 | 1249 |
Zc3h12a,Hmox1,Cav1,Il12b,Edn1,Jak2,Bnip3,Sirt1 |
| 1.249e-02 | -4.38 | SPIRA_SMOKERS_LUNG_CANCER_UP | MSigDB lists | SPIRA_SMOKERS_LUNG_CANCER_UP | 40 | 8 | 15632 | 1249 |
Rgs1,Pla2g4a,Cxcl1,Cd164,Dusp6,Cd55,Fos,Aida |
| 1.249e-02 | -4.38 | KEGG_BLADDER_CANCER | MSigDB lists | KEGG_BLADDER_CANCER | 40 | 8 | 15632 | 1249 |
Thbs1,Myc,Cdkn1a,Ccnd1,Mdm2,Vegfc,Mmp9,Map2k1 |
| 1.249e-02 | -4.38 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_UP | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_UP | 118 | 17 | 15632 | 1249 |
Lrrc8c,Icam1,Ak4,Il18,Slc30a4,Ldha,Tpi1,Glipr2,Errfi1,Ogfrl1,Stx6,Ddit4,Zc3h12c,Slc2a1,Eno1,Srm,Txnrd1 |
| 1.249e-02 | -4.38 | GSE17721_LPS_VS_POLYIC_12H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_12H_BMDC_UP | 185 | 24 | 15632 | 1249 |
Traf1,Gclc,Pilra,Ctu1,Srm,Aoah,Irf4,Adora2b,Traf3ip2,St3gal1,Jak2,Serpine1,Heatr6,Pde4b,Eif4g2,Smpdl3b,Jag1,St3gal5,Nfkbib,Pdlim7,Trim21,Csf1,Spen,Icosl |
| 1.249e-02 | -4.38 | GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 185 | 24 | 15632 | 1249 |
Plagl2,Aff1,Tab2,Prnp,Upp1,Trim13,Nek6,Pgs1,Jun,Plekhf2,Plod3,Klf6,Nfil3,Nlgn2,Hcls1,Rbms1,Slc43a3,Socs3,Atp10a,Slc9a1,Serpine1,Plod2,Gja1,Birc3 |
| 1.249e-02 | -4.38 | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_DN | 185 | 24 | 15632 | 1249 |
Itga4,Nek6,Nod1,Klf3,Spn,Srm,Acpp,Zyx,Ppa1,Rcn1,Cox18,Fam111a,Frmd4a,Mcm6,Acsl5,Dek,Pkp4,Htr2b,Pmepa1,Mthfd1l,Trim14,Timeless,Pdss1,Stat4 |
| 1.249e-02 | -4.38 | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_UP | MSigDB lists | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_UP | 185 | 24 | 15632 | 1249 |
Myo10,Aff1,Rab3ip,Sla,Slc25a25,Sdc4,Agtrap,Sell,Sdc1,Tmem176b,Hhex,Tnc,Ets2,Klf3,Cenpe,Axl,Acp2,Serpinb2,Cdc42ep4,Hat1,Timeless,Srxn1,Reps1,Asns |
| 1.252e-02 | -4.38 | Negative regulation of the PI3K/AKT network | REACTOME pathways | R-MMU-199418 | 91 | 15 | 8608 | 757 |
Pik3cd,Pdgfrb,Ppp2r1b,Cd86,Kitl,Pdgfb,Met,Ier3,Phlpp1,Src,Phlpp2,Ppp2r5a,Trib3,Irs2,Cd80 |
| 1.252e-02 | -4.38 | WANG_LMO4_TARGETS_DN | MSigDB lists | WANG_LMO4_TARGETS_DN | 327 | 38 | 15632 | 1249 |
Tmod3,Hmgcs1,Phf11d,Phf6,Clcf1,Dusp16,Ahrr,Pdk3,Rabgef1,Slc7a2,Heatr6,Ubr4,Ociad1,Zc3h7a,Rictor,Evl,Ddx60,Nfkbiz,Ifih1,Papss2,Dtx3l,Tmtc2,Phf11a,Samhd1,Phf11c,Ncoa7,Spryd7,Dync1h1,Phf11b,Jun,Znfx1,Bbx,Tgs1,Rab11fip1,Fut8,Irgq,Optn,Ap3b1 |
| 1.257e-02 | -4.38 | phosphatidylinositol binding | molecular function | GO:0035091 | 247 | 27 | 20217 | 1400 |
Plekha4,Plekhn1,Cyth3,Apba1,Tulp3,Plekha5,Rnf34,Dennd1b,Gsdmd,Aida,Plekha2,Snx2,Snx10,Adap2,Wdfy1,Kcnj2,Mitd1,Sgk3,Zcchc2,Rubcnl,Fcho2,Plekhf2,Fchsd2,Cgas,Itpr1,Plek,Myo1b |
| 1.259e-02 | -4.37 | ovulation cycle | biological process | GO:0042698 | 56 | 9 | 20694 | 1406 |
Sirt1,Src,Igf1r,Nos2,Egr1,Pla2g4a,Stat5a,Axl,Inhba |
| 1.259e-02 | -4.37 | lipid phosphorylation | biological process | GO:0046834 | 56 | 9 | 20694 | 1406 |
Cish,Inpp1,Socs3,Dgkh,Socs7,Pik3cd,Dgka,Socs1,Pikfyve |
| 1.260e-02 | -4.37 | GO_REGULATION_OF_HORMONE_SECRETION | MSigDB lists | GO_REGULATION_OF_HORMONE_SECRETION | 245 | 30 | 15632 | 1249 |
Gpr68,Kdm5b,Prkce,Rab11fip1,Il6,Edn1,Slc2a1,Serp1,Itpr1,Tnf,Cd38,Htr2a,Slc16a1,Pim3,Irs2,Hif1a,Lif,Inhba,Osm,Nos2,Ccl5,Gja1,H2-Eb1,Il1b,Nlgn2,Hcar2,Pfkl,Cacna1d,Jak2,Ptger4 |
| 1.261e-02 | -4.37 | FOX_Q2 | MSigDB lists | FOX_Q2 | 195 | 25 | 15632 | 1249 |
Egr2,Stap1,Prdx5,Errfi1,Tet2,Swap70,Rab3ip,Crim1,Bcor,Prdm1,Ccnd2,Atxn7l1,Ext1,Vasn,Map4k4,Junb,Lmo4,Gcnt2,Tnfsf10,Bambi,Zhx2,Prkar2b,Cdkn1a,Cpeb4,Nr4a3 |
| 1.262e-02 | -4.37 | CD80_C2-set | interpro domains | IPR013162 | 36 | 7 | 19984 | 1430 |
Cd274,Nectin2,Pvr,Cd200r4,Icosl,Nectin4,Cd80 |
| 1.263e-02 | -4.37 | UEDA_PERIFERAL_CLOCK | MSigDB lists | UEDA_PERIFERAL_CLOCK | 156 | 21 | 15632 | 1249 |
Nfil3,Rcl1,Idi1,Gclc,Rbms1,Il4ra,Kat2b,Spata13,Col18a1,Hmgcs1,St3gal1,Mcm10,Rbpms,St3gal5,Alas1,Pnp2,Bnip3,Dnaja1,Tnfrsf1b,Sqstm1,Hsph1 |
| 1.263e-02 | -4.37 | regulation of dephosphorylation | biological process | GO:0035303 | 194 | 22 | 20694 | 1406 |
Rcan1,Ppp4r2,Ppp2r3a,Ppp2r2a,Bmp2,Marf1,Ppp1r15b,Ppp1r14b,Plek,Ppp1r15a,Pdgfrb,Swap70,Ppp6r1,Ppp2r5a,Ripk3,Ahr,Tnf,Phactr4,Spred1,Ppp2r1b,Vcan,Jak2 |
| 1.263e-02 | -4.37 | GO_ACUTE_PHASE_RESPONSE | MSigDB lists | GO_ACUTE_PHASE_RESPONSE | 48 | 9 | 15632 | 1249 |
Stat3,Il1rn,Il6,Plscr1,Il1b,Hp,Ass1,Hif1a,Il1a |
| 1.263e-02 | -4.37 | GO_INTERACTION_WITH_SYMBIONT | MSigDB lists | GO_INTERACTION_WITH_SYMBIONT | 48 | 9 | 15632 | 1249 |
Zc3h12a,Ccl5,Casp8,Jun,Rab9,Ccl4,Pcx,Trem1,Hdac1 |
| 1.264e-02 | -4.37 | threonine-type endopeptidase activity | molecular function | GO:0004298 | 21 | 5 | 20217 | 1400 |
Psmb8,Psmb10,Psma6,Psmb6,Psmb9 |
| 1.264e-02 | -4.37 | carbohydrate kinase activity | molecular function | GO:0019200 | 21 | 5 | 20217 | 1400 |
Pfkl,Hk2,Hk1,Hk3,Pfkfb3 |
| 1.264e-02 | -4.37 | threonine-type peptidase activity | molecular function | GO:0070003 | 21 | 5 | 20217 | 1400 |
Psmb10,Psmb8,Psma6,Psmb6,Psmb9 |
| 1.267e-02 | -4.37 | STAT6_02 | MSigDB lists | STAT6_02 | 235 | 29 | 15632 | 1249 |
Cnn2,Stat5a,Flt1,Csf3r,Dock4,Tank,Cited2,Hmga1,Mtus1,Ly75,Stap1,Edn1,Mllt6,Rin2,Cox17,Hhex,Bmp2,Ccdc88b,Tmc3,Rgs3,Pdgfrb,Cd274,Pstpip2,Vasp,Dnaja2,Slc31a1,Pim2,Cpeb4,Tfec |
| 1.268e-02 | -4.37 | GSE34006_WT_VS_A2AR_KO_TREG_UP | MSigDB lists | GSE34006_WT_VS_A2AR_KO_TREG_UP | 205 | 26 | 15632 | 1249 |
Myd88,Plau,Slc48a1,H2-Q7,Aim2,Ier2,Prdm1,Irf4,Gadd45g,H2-Q4,H2-Q6,Arid5a,Mgat1,Sh3bgrl2,Rnf19b,Kpna3,Casp7,Socs3,Nfkbib,Ube2e2,Junb,Tnfrsf1b,Ccne1,Csrp1,Il10,Lmo4 |
| 1.271e-02 | -4.37 | ALFANO_MYC_TARGETS | MSigDB lists | ALFANO_MYC_TARGETS | 225 | 28 | 15632 | 1249 |
Kctd12,Rapgef2,Phlda1,Slpi,Zeb1,Ppp1r15a,Csrp1,Plaur,Clcn7,Asb13,Kif3c,Irf1,Ak4,Filip1l,Larp1,Myc,Pnp2,Dusp2,Mdn1,Agrn,Abcc5,Ccl12,Ehd1,Mvp,Slc16a1,Sdc4,Plau,Sdc1 |
| 1.272e-02 | -4.36 | phosphatase regulator activity | molecular function | GO:0019208 | 84 | 12 | 20217 | 1400 |
Ppp1r15a,Ppp2r2a,Ppp1r15b,Rcan1,Ppp2r1b,Ppp2r5a,Bmp2,Ppp4r2,Ppp2r3a,Ppp1r14b,Ppp1r12b,Phactr4 |
| 1.274e-02 | -4.36 | IKEDA_MIR30_TARGETS_UP | MSigDB lists | IKEDA_MIR30_TARGETS_UP | 109 | 16 | 15632 | 1249 |
Slc4a7,Arid4a,P4ha1,Map4k4,Ptpn2,Jun,Rai14,Peli1,Acvr1,Cpeb4,Fndc3a,Ccnd2,Irs2,Arf4,Rap2c,Chd9 |
| 1.277e-02 | -4.36 | cell cycle process | biological process | GO:0022402 | 762 | 68 | 20694 | 1406 |
Smc5,Phgdh,Syne2,Ccnd2,Mcmbp,Acvr1b,Atm,Ddx4,Marf1,Map2k1,Rrs1,Gem,Ccne1,Casp2,Whamm,Mitd1,Timeless,Thbs1,Plk2,Sass6,Prdm9,Ccnd1,Spire1,Inhba,Crlf3,Sbds,Top3a,Chmp4b,Notch1,Rgs14,Pttg1,Mcm6,Gpsm2,Ier3,Mdm2,Gpr132,Plk3,Rhou,Pnpt1,Daxx,Slfn1,Trim36,Cenpe,Cenpj,Mecp2,Abcb1a,Tpx2,Hinfp,Acvr1,Ccnj,Pim2,Cdkn1a,Pml,Rbbp8,Ezr,Irf1,Rgcc,Slc16a1,Spry2,Ccng2,Notch2,Cdkn2d,Dync1h1,Hspa2,Trip13,Il12b,Rhoc,Myc |
| 1.278e-02 | -4.36 | Hsp90 protein binding | molecular function | GO:0051879 | 46 | 8 | 20217 | 1400 |
Ksr1,Hif1a,Nod2,Nr3c1,Ahr,Nos2,Ahsa1,Stip1 |
| 1.279e-02 | -4.36 | KANG_IMMORTALIZED_BY_TERT_UP | MSigDB lists | KANG_IMMORTALIZED_BY_TERT_UP | 82 | 13 | 15632 | 1249 |
Pdgfc,Serpinb2,Pcdh7,Vcam1,Nsmaf,Icam1,C3,St3gal5,Bnip3,Pdgfb,Tnc,Eno1,P4ha2 |
| 1.279e-02 | -4.36 | TIEN_INTESTINE_PROBIOTICS_2HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_2HR_DN | 82 | 13 | 15632 | 1249 |
Nck1,Etnk1,Nox1,Ptgs2,Phip,Crim1,N4bp1,Map4k4,Flrt3,Armcx6,Cebpd,Mmd,Rapgef2 |
| 1.291e-02 | -4.35 | GSE3982_DC_VS_NKCELL_DN | MSigDB lists | GSE3982_DC_VS_NKCELL_DN | 166 | 22 | 15632 | 1249 |
Stap1,H2-Q4,Cst7,Flrt3,Sp140,H2-Q6,Ankrd17,Cd34,Smg7,Marcksl1,H2-Q7,Rhoh,Sell,Tpx2,Syne2,Fcgr4,Gch1,Irf7,Ptch1,Tnfsf10,Gfi1,Mefv |
| 1.291e-02 | -4.35 | GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN | MSigDB lists | GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN | 166 | 22 | 15632 | 1249 |
Jak2,Nfxl1,Uaca,Gbe1,Rnf145,Dnajb4,Phlda1,Ikzf1,Irf4,Ddit4,Ggct,Egln3,Rapgef2,Map4k4,Crbn,Jarid2,Hivep2,Sipa1l1,Pdgfrb,Swap70,Arhgef3,Vezt |
| 1.292e-02 | -4.35 | LIM_MAMMARY_LUMINAL_MATURE_DN | MSigDB lists | LIM_MAMMARY_LUMINAL_MATURE_DN | 91 | 14 | 15632 | 1249 |
Tpst1,Lmo4,Map4k4,Casp1,Ccl12,Gypc,Fzd1,Kctd12,Htra1,Irs2,Frmd4a,Mob3b,Fas,Col4a2 |
| 1.292e-02 | -4.35 | GO_PML_BODY | MSigDB lists | GO_PML_BODY | 91 | 14 | 15632 | 1249 |
Smc5,Pml,Max,Ikbke,Ciita,Daxx,N4bp1,Sqstm1,Sp140,Morc3,Rgs14,Top3a,Isg20,Sirt1 |
| 1.292e-02 | -4.35 | negative regulation of ossification | biological process | GO:0030279 | 96 | 13 | 20694 | 1406 |
Lrp4,Kremen1,Ahr,Tnf,Srgn,P2ry2,Bcor,Ptch1,Hif1a,Ccr1,Notch1,Adrb2,Noct |
| 1.292e-02 | -4.35 | transition metal ion transport | biological process | GO:0000041 | 96 | 13 | 20694 | 1406 |
Slc39a4,Slc31a1,Slc30a4,Slc31a2,Ap3b1,Slc48a1,Myo1b,Slc30a1,Slc39a13,Slc39a14,Cp,Slc25a37,Lcn2 |
| 1.295e-02 | -4.35 | positive regulation of purine nucleotide metabolic process | biological process | GO:1900544 | 38 | 7 | 20694 | 1406 |
Htr2a,Myc,Stat3,Adora2b,Pid1,Map2k1,Nos2 |
| 1.295e-02 | -4.35 | positive regulation of nucleotide metabolic process | biological process | GO:0045981 | 38 | 7 | 20694 | 1406 |
Pid1,Adora2b,Map2k1,Nos2,Htr2a,Myc,Stat3 |
| 1.295e-02 | -4.35 | positive regulation of myotube differentiation | biological process | GO:0010831 | 38 | 7 | 20694 | 1406 |
Tnfsf14,Il4ra,Mmp14,Ehd1,Ccl8,Gdf15,Cxcl9 |
| 1.295e-02 | -4.35 | negative regulation of cell-matrix adhesion | biological process | GO:0001953 | 38 | 7 | 20694 | 1406 |
Acvrl1,Src,Bcl6,Thbs1,Jag1,Serpine1,Mmp14 |
| 1.295e-02 | -4.35 | regulation of mitotic spindle organization | biological process | GO:0060236 | 38 | 7 | 20694 | 1406 |
Parp3,Tpx2,Gpsm2,Chmp4b,Hspa1a,Hspa1b,Dync1h1 |
| 1.295e-02 | -4.35 | aspartate family amino acid metabolic process | biological process | GO:0009066 | 38 | 7 | 20694 | 1406 |
Tha1,Phgdh,Ass1,Asns,Mthfr,Plod2,Plod3 |
| 1.297e-02 | -4.35 | CACTGTG_MIR128A_MIR128B | MSigDB lists | CACTGTG_MIR128A_MIR128B | 307 | 36 | 15632 | 1249 |
Rnd3,Cd34,Plagl2,Arrdc4,Tmtc2,Dcp2,Slc39a13,Rab11fip1,Stk40,Cpd,Cited2,Mgat1,Prkx,Cxcl1,Rsbn1,Sh3bgrl2,Armc8,H3f3b,Agpat4,Itpkc,Itga5,Crkl,Mtdh,Frmd4a,Phf6,Med13,Csf1,Bcorl1,Tmeff1,Btg2,Dcp1a,Pde7b,Ube2e2,Sirt1,Rims3,Plk2 |
| 1.302e-02 | -4.34 | VEGF signaling pathway | KEGG pathways | mmu04370 | 58 | 11 | 7931 | 713 |
Mapkapk2,Akt3,Ptk2,Src,Pla2g4a,Sphk1,Ptgs2,Rac3,Kdr,Pik3cd,Map2k1 |
| 1.302e-02 | -4.34 | VEGF signaling pathway | KEGG pathways | ko04370 | 58 | 11 | 7931 | 713 |
Mapkapk2,Ptk2,Akt3,Src,Pla2g4a,Sphk1,Ptgs2,Rac3,Kdr,Pik3cd,Map2k1 |
| 1.304e-02 | -4.34 | regulation of amino acid transport | biological process | GO:0051955 | 47 | 8 | 20694 | 1406 |
Adora2a,Il1rn,Tnf,Il1b,Kmo,Arg2,Stxbp1,Nr3c1 |
| 1.304e-02 | -4.34 | response to endoplasmic reticulum stress | biological process | GO:0034976 | 206 | 23 | 20694 | 1406 |
Tmem67,Casp3,Itpr1,Dnajb2,Ccnd1,Rnf139,Ppp1r15a,Pmaip1,Trim13,Trib3,Ero1l,Jun,Eif2ak2,Apaf1,Nck1,Casp4,Thbs1,Fam129a,Bcl2l11,Serp1,Pml,Atf3,Ppp1r15b |
| 1.305e-02 | -4.34 | protein serine/threonine kinase activator activity | molecular function | GO:0043539 | 29 | 6 | 20217 | 1400 |
Lgals9,Cdk5r1,Map2k1,Mtcp1,Irgm2,Spry2 |
| 1.305e-02 | -4.34 | protein serine/threonine kinase inhibitor activity | molecular function | GO:0030291 | 29 | 6 | 20217 | 1400 |
Prkar2b,Cdkn2d,Cdkn1a,Kat2b,Casp3,Spred1 |
| 1.305e-02 | -4.34 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process | molecular function | GO:0043027 | 29 | 6 | 20217 | 1400 |
Tnfsf14,Birc3,Serpinb9,Prdx5,Bcl2a1d,Birc2 |
| 1.306e-02 | -4.34 | SAM_2 | pfam domains | PF07647 | 36 | 7 | 18711 | 1348 |
Dgkh,Ppfibp1,Ppfibp2,Lcp2,Samsn1,Samhd1,Ppfia3 |
| 1.306e-02 | -4.34 | C2-set_2 | pfam domains | PF08205 | 36 | 7 | 18711 | 1348 |
Pvr,Cd200r4,Icosl,Nectin2,Cd80,Cd274,Nectin4 |
| 1.307e-02 | -4.34 | BH domain binding | molecular function | GO:0051400 | 14 | 4 | 20217 | 1400 |
Bcl2a1a,Irgm2,Bcl2a1d,Bcl2a1b |
| 1.309e-02 | -4.34 | SPR | prosite domains | PS51227 | 7 | 3 | 13278 | 1037 |
Spry2,Spred3,Spred1 |
| 1.309e-02 | -4.34 | SAND | prosite domains | PS50864 | 7 | 3 | 13278 | 1037 |
Sp140,Sp110,Sp100 |
| 1.309e-02 | -4.34 | GS | prosite domains | PS51256 | 7 | 3 | 13278 | 1037 |
Acvr1b,Acvrl1,Acvr1 |
| 1.313e-02 | -4.33 | TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | REACTOME pathways | R-MMU-5676594 | 17 | 5 | 8608 | 757 |
Birc3,Birc2,Cd40,Tnfsf14,Traf2 |
| 1.313e-02 | -4.33 | Interferon gamma signaling | REACTOME pathways | R-MMU-877300 | 17 | 5 | 8608 | 757 |
Stat1,Socs3,Socs1,Jak2,Ptpn2 |
| 1.313e-02 | -4.33 | regulation of cell cycle phase transition | biological process | GO:1901987 | 288 | 30 | 20694 | 1406 |
Mecp2,Atm,Nek6,Atp2b4,Dcun1d3,Psme2,Cenpe,Ccnd2,Plk3,Pdpn,Slfn1,Tmod3,Cdkn1a,Ccne1,Casp2,Pml,Ccl12,Ankrd17,Ube2e2,Hspa2,Trip13,Rbl1,Cdkn2d,Pbx1,Ccnd1,Rgcc,Mdm2,Gpr132,Ier3,Psme1 |
| 1.313e-02 | -4.33 | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_DN | MSigDB lists | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_DN | 176 | 23 | 15632 | 1249 |
Klf6,Pik3r5,Cyth3,Tab2,Gbe1,Il4ra,St3gal6,Card6,Klf2,Ppm1k,Icosl,Btg2,Ampd3,Irf1,Acvr1b,Rab20,Ier3,Clcf1,Ust,Ldlr,Zhx2,Dnajb2,Wdr43 |
| 1.313e-02 | -4.33 | GSE27786_NEUTROPHIL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_NEUTROPHIL_VS_MONO_MAC_UP | 176 | 23 | 15632 | 1249 |
Rcsd1,Rab20,Smox,Dck,Cmpk2,Znrf1,Zcchc2,Tap2,Lgals9,Casp4,Sipa1l1,Junb,Dgka,Coa5,Arg2,Zfp319,Clec4e,Mtus1,Csf3r,Gsdmd,Rsad2,Nr3c1,Slc15a3 |
| 1.313e-02 | -4.33 | GSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | 176 | 23 | 15632 | 1249 |
Lpcat2,Ccdc88b,Cd300lf,Irak2,Fcgr1,Inpp1,Fam102b,Crlf3,Znrf1,Hsd17b7,Pdgfc,Lrp8,Clec4d,Pigv,Pttg1,Pde1b,Gclm,Cpd,Ccdc25,Mmd,Cnn2,Oas3,Cited2 |
| 1.313e-02 | -4.33 | GSE14308_TH2_VS_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE14308_TH2_VS_NAIVE_CD4_TCELL_DN | 176 | 23 | 15632 | 1249 |
Ddhd1,Tnf,Stat5a,Parp9,Dhx58,Lrch3,Slco3a1,Pttg1,Ddx58,Fcgr1,Col11a2,Rel,Psme2,Nrp2,Stx6,Rhou,Dnaja2,Usp31,Dgkh,Gpd2,Rnf145,Phf6,Elmod2 |
| 1.313e-02 | -4.33 | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN | 176 | 23 | 15632 | 1249 |
Samsn1,Cav1,Tor3a,Rapgef2,Smpdl3b,Ext1,Rcn1,Trib1,Cdkn1a,Ralgds,Sec24a,Cflar,Cited2,Mgat1,Timp1,B4galt4,Srm,Optn,Sdc1,Nfkbil1,Cd38,Slamf7,Cd14 |
| 1.313e-02 | -4.33 | GSE20715_0H_VS_24H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_24H_OZONE_LUNG_UP | 176 | 23 | 15632 | 1249 |
Evl,Prdm1,Sell,Cyth3,Gng11,Gnb4,Tmod3,Rtn1,Il2rg,Ms4a6d,Tnfsf10,Kdr,Ppfibp2,Csrp1,Ccl5,S100a8,Casp8,Nrp2,Tmeff1,Trim21,Ppp2r3a,Parp12,Snx2 |
| 1.313e-02 | -4.33 | PIGF_UP.V1_UP | MSigDB lists | PIGF_UP.V1_UP | 176 | 23 | 15632 | 1249 |
Pla2g4a,Sat1,Nat2,Mafk,Vcan,Cpd,Spryd7,Mark2,Hif1a,Dcp2,Ccl22,Arl4a,Stxbp3,Syne2,4930523C07Rik,Slc4a7,Ascc3,Cep350,Rrs1,Tnfsf10,Ripk2,Ptgs2,Map2k4 |
| 1.313e-02 | -4.33 | GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_DN | MSigDB lists | GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_DN | 176 | 23 | 15632 | 1249 |
Ahsa1,Phf11a,Ifi207,Phf11c,Rnf139,Ifi214,Rbpms,Triobp,Hsph1,Phf11b,Ifi213,Ifi209,Ifi205,Vegfc,Ptk2,Phf11d,Ifi204,Nsmaf,Ifi211,Ifi208,Ifi203,Mndal,Ascc3 |
| 1.313e-02 | -4.33 | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN | 176 | 23 | 15632 | 1249 |
Tmem229b,Ripk2,Zc3h12a,Hsd17b7,Cd300lf,Heatr6,Zc3h12c,Cd86,Tmeff1,Arl4a,Ppm1l,Hif1a,Batf,Sav1,Tcf4,Cyfip1,Ezr,Chst11,Mecp2,Mllt6,4932438A13Rik,Dusp2,D1Ertd622e |
| 1.313e-02 | -4.33 | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN | 176 | 23 | 15632 | 1249 |
Irf1,Ddx58,Ccnd2,Il2rg,Spred3,St3gal1,Csrnp1,Agpat4,Lrrc8c,Gtpbp2,Ccl4,Tcf4,Plekha2,Axl,Arid4a,Gch1,Phlpp1,Phactr4,Parp14,Tbc1d1,Procr,Ifi44,Fchsd2 |
| 1.313e-02 | -4.33 | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | 176 | 23 | 15632 | 1249 |
Casp3,Sdc2,Aebp2,Hdac1,Treml2,Vasp,Ifit1bl2,Gsdmd,Ifit1bl1,Abcc5,Rnf31,Rhbdf2,Cited2,Pilrb1,Pilrb2,Slc48a1,Cmpk2,Abcc4,Ebi3,Max,Stat1,Gpd2,Arrdc4 |
| 1.313e-02 | -4.33 | GSE24492_LYVE_NEG_VS_POS_MACROPHAGE_UP | MSigDB lists | GSE24492_LYVE_NEG_VS_POS_MACROPHAGE_UP | 176 | 23 | 15632 | 1249 |
Tspan3,Ttc39c,Otud1,Klf6,Parp8,Ogfrl1,Tmem171,Gpr84,Cp,Slco3a1,Pml,Stxbp1,Tlr6,Pdgfc,Slc25a25,Snx10,Etv6,Rilpl1,Egr3,Kdm6b,Tagap,Ppp2r2a,Cldnd1 |
| 1.313e-02 | -4.33 | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_UP | MSigDB lists | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_UP | 176 | 23 | 15632 | 1249 |
Slc30a4,Rars,Sgk3,Myo10,Pik3r5,Dpy19l1,Dse,Itpr1,Acpp,Ikzf1,Cers6,Pde5a,Cd200r4,Kremen1,Pim2,Atp10a,Gpd2,Sema4a,Acvr1b,Snn,Ccl5,Lmo4,Daam1 |
| 1.313e-02 | -4.33 | C-type_lectin-like/link_sf | interpro domains | IPR016186 | 132 | 17 | 19984 | 1430 |
Olr1,Clec4n,Clec4e,Col18a1,Cd302,Clec4a1,Klrk1,Clec2d,Vcan,Cd69,Sele,Sell,Clec5a,Layn,Ly75,Clec4d,Klra2 |
| 1.314e-02 | -4.33 | BASSO_B_LYMPHOCYTE_NETWORK | MSigDB lists | BASSO_B_LYMPHOCYTE_NETWORK | 128 | 18 | 15632 | 1249 |
Eef1e1,Slc39a14,Slc7a5,Trip13,Sat1,Cycs,Zyx,Casp4,Itpr1,Asns,Tnfrsf1b,Mvp,Mdfic,Ahsa1,Tpx2,Ccnd2,Uchl1,Hhex |
| 1.314e-02 | -4.33 | NRL_DN.V1_UP | MSigDB lists | NRL_DN.V1_UP | 128 | 18 | 15632 | 1249 |
St3gal1,Arg2,Tnfaip2,Dusp14,Tnfaip3,Plagl2,Nlgn2,Plekhf2,Ahrr,Bcl2l11,Plekha2,Gpsm2,Lad1,Ttc39c,Spen,Sap30,Ext1,Bst1 |
| 1.316e-02 | -4.33 | negative regulation of mitotic cell cycle phase transition | biological process | GO:1901991 | 128 | 16 | 20694 | 1406 |
Cenpe,Dcun1d3,Rbl1,Trip13,Atm,Rgcc,Slfn1,Ccnd1,Plk3,Ier3,Gpr132,Mdm2,Ccl12,Casp2,Pml,Cdkn1a |
| 1.316e-02 | -4.33 | phosphatidylinositol-mediated signaling | biological process | GO:0048015 | 66 | 10 | 20694 | 1406 |
Pik3r6,Ezr,Edn1,Htr2b,Pdgfrb,Ptafr,Pik3cd,Pik3r5,Igf1r,Htr2a |
| 1.316e-02 | -4.33 | apoptotic mitochondrial changes | biological process | GO:0008637 | 66 | 10 | 20694 | 1406 |
Gclc,Pim2,Sod2,Jun,Pmaip1,Ggct,Bcl2l11,Gclm,Bnip3,Hk2 |
| 1.316e-02 | -4.33 | GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN | MSigDB lists | GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN | 147 | 20 | 15632 | 1249 |
Bcor,Tlr6,Prdm9,Prkx,Cldnd1,Tmem67,Olfml3,Prkar2b,Ppp2r2a,Tnfrsf14,Stau1,Pde4b,Sik3,Golga3,Stat3,Cers6,Arhgap26,Rictor,Ap3b1,Phlpp1 |
| 1.318e-02 | -4.33 | stress fiber | cellular component | GO:0001725 | 86 | 12 | 20747 | 1409 |
Daam1,Micall2,Palld,Cnn2,Tpm4,Flnb,Zyx,Ptk2,Fscn1,Dst,Pdlim7,Actb |
| 1.318e-02 | -4.33 | contractile actin filament bundle | cellular component | GO:0097517 | 86 | 12 | 20747 | 1409 |
Actb,Pdlim7,Dst,Fscn1,Ptk2,Zyx,Flnb,Tpm4,Cnn2,Palld,Micall2,Daam1 |
| 1.318e-02 | -4.33 | CACTGCC_MIR34A_MIR34C_MIR449 | MSigDB lists | CACTGCC_MIR34A_MIR34C_MIR449 | 256 | 31 | 15632 | 1249 |
Abr,Slco3a1,Zfp281,Notch1,Axl,Bcl6,Tmem184b,Ppp2r5a,Ntng2,Fut8,Arhgap26,Cnot4,Ldha,Sema4c,Acsl1,Frmd4a,Gpr85,Osgin2,Cacnb3,Kitl,Ralgds,Notch2,Pkp4,Serpine1,Map2k1,Daam1,Vezt,Met,Casp2,Ppp2r3a,Jag1 |
| 1.320e-02 | -4.33 | cyclin D2-CDK4 complex | cellular component | GO:0097129 | 3 | 2 | 20747 | 1409 |
Ccnd2,Cdkn2d |
| 1.320e-02 | -4.33 | CNTFR-CLCF1 complex | cellular component | GO:0097059 | 3 | 2 | 20747 | 1409 |
Clcf1,Ebi3 |
| 1.320e-02 | -4.33 | procollagen-proline 4-dioxygenase complex | cellular component | GO:0016222 | 3 | 2 | 20747 | 1409 |
P4ha1,P4ha2 |
| 1.320e-02 | -4.33 | TAP complex | cellular component | GO:0042825 | 3 | 2 | 20747 | 1409 |
Tap2,Tap1 |
| 1.320e-02 | -4.33 | apoptosome | cellular component | GO:0043293 | 3 | 2 | 20747 | 1409 |
Apaf1,Uaca |
| 1.320e-02 | -4.33 | Noc complex | cellular component | GO:0030689 | 3 | 2 | 20747 | 1409 |
Noc4l,Casp8 |
| 1.320e-02 | -4.33 | platelet dense granule membrane | cellular component | GO:0031088 | 3 | 2 | 20747 | 1409 |
Abcc4,Itpr1 |
| 1.320e-02 | -4.33 | AIM2 inflammasome complex | cellular component | GO:0097169 | 3 | 2 | 20747 | 1409 |
Aim2,Casp1 |
| 1.320e-02 | -4.33 | phosphatidylinositol 3-kinase complex, class IB | cellular component | GO:0005944 | 3 | 2 | 20747 | 1409 |
Pik3r6,Pik3r5 |
| 1.321e-02 | -4.33 | mouse chr1|1 G3 | chromosome location | mouse chr1|1 G3 | 33 | 6 | 24173 | 1464 |
Tor3a,Smg7,Cep350,Tor1aip2,Stx6,Tor1aip1 |
| 1.321e-02 | -4.33 | positive regulation of vitamin D biosynthetic process | biological process | GO:0060557 | 3 | 2 | 20694 | 1406 |
Tnf,Il1b |
| 1.321e-02 | -4.33 | negative regulation of endothelial cell chemotaxis | biological process | GO:2001027 | 3 | 2 | 20694 | 1406 |
Notch1,Thbs1 |
| 1.321e-02 | -4.33 | prostaglandin secretion | biological process | GO:0032310 | 3 | 2 | 20694 | 1406 |
Abcc4,Nos2 |
| 1.321e-02 | -4.33 | helper T cell diapedesis | biological process | GO:0035685 | 3 | 2 | 20694 | 1406 |
Crkl,Ccl5 |
| 1.321e-02 | -4.33 | cytosol to endoplasmic reticulum transport | biological process | GO:0046967 | 3 | 2 | 20694 | 1406 |
Tap2,Tap1 |
| 1.321e-02 | -4.33 | negative regulation of interleukin-1 alpha production | biological process | GO:0032690 | 3 | 2 | 20694 | 1406 |
Ptger4,Cx3cl1 |
| 1.321e-02 | -4.33 | negative regulation of dendritic cell antigen processing and presentation | biological process | GO:0002605 | 3 | 2 | 20694 | 1406 |
Fgl2,Thbs1 |
| 1.321e-02 | -4.33 | negative regulation of hypersensitivity | biological process | GO:0002884 | 3 | 2 | 20694 | 1406 |
Fcgr2b,Spn |
| 1.321e-02 | -4.33 | regulation of hippocampal neuron apoptotic process | biological process | GO:0110089 | 3 | 2 | 20694 | 1406 |
Cx3cr1,Cx3cl1 |
| 1.321e-02 | -4.33 | negative regulation of myoblast fusion | biological process | GO:1901740 | 3 | 2 | 20694 | 1406 |
Cxcl10,Cflar |
| 1.321e-02 | -4.33 | regulation of transposition, RNA-mediated | biological process | GO:0010525 | 3 | 2 | 20694 | 1406 |
Mov10,Tut7 |
| 1.321e-02 | -4.33 | positive regulation of dendritic cell apoptotic process | biological process | GO:2000670 | 3 | 2 | 20694 | 1406 |
Rapgef2,Lyn |
| 1.321e-02 | -4.33 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis | biological process | GO:2001271 | 3 | 2 | 20694 | 1406 |
Rnf34,Rffl |
| 1.321e-02 | -4.33 | regulation of hepatocyte apoptotic process | biological process | GO:1903943 | 3 | 2 | 20694 | 1406 |
Cflar,Igf1r |
| 1.321e-02 | -4.33 | regulation of establishment of Sertoli cell barrier | biological process | GO:1904444 | 3 | 2 | 20694 | 1406 |
Abcb1a,Il1a |
| 1.321e-02 | -4.33 | positive regulation of calcidiol 1-monooxygenase activity | biological process | GO:0060559 | 3 | 2 | 20694 | 1406 |
Tnf,Il1b |
| 1.321e-02 | -4.33 | apoptotic process involved in embryonic digit morphogenesis | biological process | GO:1902263 | 3 | 2 | 20694 | 1406 |
Bcl2l11,Notch1 |
| 1.321e-02 | -4.33 | regulation of toll-like receptor 7 signaling pathway | biological process | GO:0034155 | 3 | 2 | 20694 | 1406 |
Rsad2,Treml4 |
| 1.321e-02 | -4.33 | regulation of neutrophil differentiation | biological process | GO:0045658 | 3 | 2 | 20694 | 1406 |
Ikzf1,Trib1 |
| 1.321e-02 | -4.33 | hydroxylysine metabolic process | biological process | GO:0046946 | 3 | 2 | 20694 | 1406 |
Plod2,Plod3 |
| 1.321e-02 | -4.33 | interleukin-12-mediated signaling pathway | biological process | GO:0035722 | 3 | 2 | 20694 | 1406 |
Jak2,Il12rb1 |
| 1.321e-02 | -4.33 | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process | biological process | GO:0140199 | 3 | 2 | 20694 | 1406 |
Pde4b,Atp2b4 |
| 1.321e-02 | -4.33 | regulation of matrix metallopeptidase secretion | biological process | GO:1904464 | 3 | 2 | 20694 | 1406 |
Cd200,Ptger4 |
| 1.321e-02 | -4.33 | negative regulation of hepatocyte apoptotic process | biological process | GO:1903944 | 3 | 2 | 20694 | 1406 |
Igf1r,Cflar |
| 1.321e-02 | -4.33 | positive regulation of ovarian follicle development | biological process | GO:2000386 | 3 | 2 | 20694 | 1406 |
Ptger4,Src |
| 1.321e-02 | -4.33 | positive regulation of long-chain fatty acid import into cell | biological process | GO:0140214 | 3 | 2 | 20694 | 1406 |
Acsl5,Fabp3 |
| 1.321e-02 | -4.33 | hydroxylysine biosynthetic process | biological process | GO:0046947 | 3 | 2 | 20694 | 1406 |
Plod3,Plod2 |
| 1.321e-02 | -4.33 | sphingolipid translocation | biological process | GO:0099039 | 3 | 2 | 20694 | 1406 |
Abcb1a,Abcc1 |
| 1.321e-02 | -4.33 | regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway | biological process | GO:1900238 | 3 | 2 | 20694 | 1406 |
Pdgfb,Pdgfrb |
| 1.321e-02 | -4.33 | cyclooxygenase pathway | biological process | GO:0019371 | 3 | 2 | 20694 | 1406 |
Ptgs2,Sphk1 |
| 1.321e-02 | -4.33 | positive regulation of cellular response to macrophage colony-stimulating factor stimulus | biological process | GO:1903974 | 3 | 2 | 20694 | 1406 |
Tlr2,Csf1 |
| 1.321e-02 | -4.33 | regulation of antigen processing and presentation of peptide antigen via MHC class I | biological process | GO:0002589 | 3 | 2 | 20694 | 1406 |
Tap2,Tapbpl |
| 1.321e-02 | -4.33 | positive regulation of prostaglandin-endoperoxide synthase activity | biological process | GO:0060585 | 3 | 2 | 20694 | 1406 |
Nod2,Edn1 |
| 1.321e-02 | -4.33 | negative regulation of nitric oxide mediated signal transduction | biological process | GO:0010751 | 3 | 2 | 20694 | 1406 |
Thbs1,Atp2b4 |
| 1.321e-02 | -4.33 | positive regulation of interleukin-4 biosynthetic process | biological process | GO:0045404 | 3 | 2 | 20694 | 1406 |
Icosl,Irf4 |
| 1.321e-02 | -4.33 | negative regulation of macrophage inflammatory protein 1 alpha production | biological process | GO:0071641 | 3 | 2 | 20694 | 1406 |
Mefv,Arg2 |
| 1.321e-02 | -4.33 | protein localization to Golgi membrane | biological process | GO:1903292 | 3 | 2 | 20694 | 1406 |
Arl5c,Arl5b |
| 1.321e-02 | -4.33 | phospholipase C-activating serotonin receptor signaling pathway | biological process | GO:0007208 | 3 | 2 | 20694 | 1406 |
Htr2b,Htr2a |
| 1.321e-02 | -4.33 | neutrophil apoptotic process | biological process | GO:0001781 | 3 | 2 | 20694 | 1406 |
Hcar2,Il6 |
| 1.321e-02 | -4.33 | cellular response to staurosporine | biological process | GO:0072734 | 3 | 2 | 20694 | 1406 |
Casp3,Casp7 |
| 1.321e-02 | -4.33 | regulation of protein K48-linked ubiquitination | biological process | GO:0061945 | 3 | 2 | 20694 | 1406 |
Nmi,Birc2 |
| 1.321e-02 | -4.33 | negative regulation of transposition, RNA-mediated | biological process | GO:0010526 | 3 | 2 | 20694 | 1406 |
Mov10,Tut7 |
| 1.321e-02 | -4.33 | positive regulation of protein K63-linked ubiquitination | biological process | GO:1902523 | 3 | 2 | 20694 | 1406 |
Nod2,Birc2 |
| 1.321e-02 | -4.33 | positive regulation of response to macrophage colony-stimulating factor | biological process | GO:1903971 | 3 | 2 | 20694 | 1406 |
Csf1,Tlr2 |
| 1.321e-02 | -4.33 | negative regulation of calcidiol 1-monooxygenase activity | biological process | GO:0010956 | 3 | 2 | 20694 | 1406 |
Nfkb1,Gfi1 |
| 1.321e-02 | -4.33 | negative regulation of protein kinase C signaling | biological process | GO:0090038 | 3 | 2 | 20694 | 1406 |
Phlpp1,Myadm |
| 1.321e-02 | -4.33 | negative regulation of T-helper 1 cell differentiation | biological process | GO:0045626 | 3 | 2 | 20694 | 1406 |
Tnfsf4,Il4ra |
| 1.321e-02 | -4.33 | positive regulation of interleukin-17 secretion | biological process | GO:1905078 | 3 | 2 | 20694 | 1406 |
Osm,Arid5a |
| 1.321e-02 | -4.33 | positive regulation of metanephric mesenchymal cell migration | biological process | GO:2000591 | 3 | 2 | 20694 | 1406 |
Pdgfb,Pdgfrb |
| 1.321e-02 | -4.33 | regulation of prostaglandin-endoperoxide synthase activity | biological process | GO:0060584 | 3 | 2 | 20694 | 1406 |
Edn1,Nod2 |
| 1.321e-02 | -4.33 | interferon-alpha production | biological process | GO:0032607 | 3 | 2 | 20694 | 1406 |
Irf7,Azi2 |
| 1.321e-02 | -4.33 | spermine catabolic process | biological process | GO:0046208 | 3 | 2 | 20694 | 1406 |
Smox,Sat1 |
| 1.321e-02 | -4.33 | negative regulation of growth rate | biological process | GO:0045967 | 3 | 2 | 20694 | 1406 |
Notch2,Notch1 |
| 1.321e-02 | -4.33 | negative regulation of interleukin-2 secretion | biological process | GO:1900041 | 3 | 2 | 20694 | 1406 |
Ezr,Cd34 |
| 1.321e-02 | -4.33 | regulation of chronic inflammatory response to antigenic stimulus | biological process | GO:0002874 | 3 | 2 | 20694 | 1406 |
Tnf,Il10 |
| 1.321e-02 | -4.33 | positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway | biological process | GO:0035793 | 3 | 2 | 20694 | 1406 |
Pdgfb,Pdgfrb |
| 1.321e-02 | -4.33 | positive regulation of toll-like receptor 7 signaling pathway | biological process | GO:0034157 | 3 | 2 | 20694 | 1406 |
Rsad2,Treml4 |
| 1.321e-02 | -4.33 | response to staurosporine | biological process | GO:0072733 | 3 | 2 | 20694 | 1406 |
Casp7,Casp3 |
| 1.321e-02 | -4.33 | interferon-beta production | biological process | GO:0032608 | 3 | 2 | 20694 | 1406 |
Trim56,Irf7 |
| 1.321e-02 | -4.33 | receptor internalization involved in canonical Wnt signaling pathway | biological process | GO:2000286 | 3 | 2 | 20694 | 1406 |
Cav1,Scyl2 |
| 1.327e-02 | -4.32 | GO_THIOL_DEPENDENT_UBIQUITIN_SPECIFIC_PROTEASE_ACTIVITY | MSigDB lists | GO_THIOL_DEPENDENT_UBIQUITIN_SPECIFIC_PROTEASE_ACTIVITY | 65 | 11 | 15632 | 1249 |
Otud1,Usp35,Usp12,Usp42,Usp18,Uchl1,Usp25,Usp31,Tnfaip3,Vcpip1,Tnip1 |
| 1.327e-02 | -4.32 | GO_REGULATION_OF_VASOCONSTRICTION | MSigDB lists | GO_REGULATION_OF_VASOCONSTRICTION | 65 | 11 | 15632 | 1249 |
Ptgs2,Icam1,Hif1a,Cx3cl1,Ptafr,Htr2a,Cd38,Gja1,Cav1,Dock4,Edn1 |
| 1.328e-02 | -4.32 | FG_GAP | prosite domains | PS51470 | 19 | 5 | 13278 | 1037 |
Itga9,Itgav,Itgal,Itga5,Itga4 |
| 1.329e-02 | -4.32 | inclusion body | cellular component | GO:0016234 | 76 | 11 | 20747 | 1409 |
Fgr,Sqstm1,Nxf1,Ifi204,Prnp,Dnajb2,Hap1,Hspa1a,Gys1,Syne2,Klf8 |
| 1.329e-02 | -4.32 | GSE41867_NAIVE_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | 186 | 24 | 15632 | 1249 |
Mllt6,Pou2f2,Akt3,Ddit4,Pde1b,Atxn7l1,Aftph,Golga3,Slc2a1,Sik3,Mdfic,Sgk3,Rsbn1,F10,Prkx,Ralgds,Tspo,Chic2,Grina,Rab19,Etv3,Arl4a,Fgr,Zfp513 |
| 1.329e-02 | -4.32 | GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_UP | 186 | 24 | 15632 | 1249 |
Psmb9,Timp1,Mgat1,Casp1,C1ra,Oaf,Ctsc,Agtrap,Hk3,Gbp2,Fbxo4,Irf8,Pid1,Gbp7,Snx10,Rgl1,Smpdl3b,Nrp2,Tifa,Irf1,Ms4a6d,Dram1,Dennd2a,Stat1 |
| 1.329e-02 | -4.32 | GSE43955_10H_VS_60H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_10H_VS_60H_ACT_CD4_TCELL_UP | 186 | 24 | 15632 | 1249 |
Prdx1,Ciita,Batf,Itga4,Ch25h,F11r,Fpr2,Gmppb,Fgr,Ppp2r5a,Tlk2,Sqstm1,Tnip1,Fam20c,Rtn1,Ifit3b,Procr,Psmb8,S100a8,Ifit3,Rrs1,Lcn2,Fubp1,Cep350 |
| 1.329e-02 | -4.32 | GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP | 186 | 24 | 15632 | 1249 |
Slc2a1,Crbn,Bcl2a1b,Bcl2a1d,Slc15a3,Etv3,Sdc1,Aldh1b1,Aff1,Clcn5,Rras2,Gng11,Vezt,Plekha2,Igsf8,Rrs1,Cdyl,Syne2,Fzd1,Mob3b,Osgin2,Ptk2,Cflar,Bcl2a1a |
| 1.329e-02 | -4.32 | GSE20715_0H_VS_6H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_6H_OZONE_LUNG_DN | 186 | 24 | 15632 | 1249 |
Gclc,Cd14,Cxcl1,Pfkfb3,Rhoc,Frmd6,Notch1,Socs3,Hp,Rab20,Tlr2,Cdc42ep4,Trib1,Slc43a3,Osgin2,Acvr1b,Cp,Spen,Rictor,Errfi1,Dusp6,Bcl2l11,Txnrd1,Cdyl |
| 1.329e-02 | -4.32 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_DN | 186 | 24 | 15632 | 1249 |
Ifi209,Ifi205,Plod3,Dync1h1,Ifi213,Acvr1,Nat2,Ifi214,Prdm1,Rbl1,Ifi207,Aff1,Mndal,Flrt2,Slc7a8,Jarid2,Ifi203,Ifi208,Ifi211,Cdc42ep4,Adora2b,Ifi204,Gng4,Gcnt2 |
| 1.329e-02 | -4.32 | GSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_DN | MSigDB lists | GSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_DN | 186 | 24 | 15632 | 1249 |
Irgm2,Ddit4,Rhoq,Il6,Cdyl2,Rnf19a,Hk2,Pde7b,Tyk2,Gsdmd,Fam43a,Casp4,Ptpn2,Osm,Jak2,Tnip1,Igf2bp2,Vegfc,Snn,Rnf19b,Lif,Osgin2,Mafg,Rab20 |
| 1.329e-02 | -4.32 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS | 246 | 30 | 15632 | 1249 |
Gbe1,St3gal6,Pigv,Upp1,St3gal3,Parp10,Zc3hav1,Gys1,Extl2,Tiparp,Mgat1,B4galt4,Plod3,Parp8,Dpy19l1,B3gnt5,Parp9,Pnp2,Parp14,Fut8,Parp11,Parp3,St3gal1,Gcnt2,Nampt,Parp12,Sirt1,Gbgt1,St3gal5,Ext1 |
| 1.329e-02 | -4.32 | NF1_Q6_01 | MSigDB lists | NF1_Q6_01 | 246 | 30 | 15632 | 1249 |
Stat3,Ntng2,Rhoq,Itgb8,Acvr1,Tlk2,Mid1,Nfkbia,Rapgef5,Tank,Cited2,Serp1,Zbtb5,Prdx1,Dusp14,Csrnp1,Nr1h3,Bcl9,Eif4g2,Jdp2,Sesn3,Mov10,Col11a2,Igsf8,Cd82,H3f3b,Sema4c,Tmem229b,Dnajb4,Lox |
| 1.330e-02 | -4.32 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | 607 | 64 | 15632 | 1249 |
Lif,Sla,Cd40,Eno1,Tcf4,Gpsm2,Swap70,Slc16a3,Arid5b,St7,Lox,Pim1,Ldha,Psmb6,Pgk1,Trafd1,Abcc4,Keap1,Stip1,Inpp1,Thbs1,Fubp1,Fzd5,Csrp1,Spint2,Wars,G3bp2,Slc2a6,Gmppb,Tpi1,Tmem176b,Prpf4,Rbl1,Enpp4,Ets2,Sqstm1,Cenpe,Optn,Cept1,Pla2g4a,Ggct,Fam111a,Odc1,Ppa1,Filip1l,Hmgcs1,Ptk2,Prkar2b,Pfkl,Idi1,Ldlr,Ppp2r1b,Actb,Lmo4,Plod2,Hdc,Heatr6,Sema3c,Eno2,Psat1,Pdk3,Trip13,Timeless,Pstpip2 |
| 1.331e-02 | -4.32 | GO_REGULATION_OF_SYSTEM_PROCESS | MSigDB lists | GO_REGULATION_OF_SYSTEM_PROCESS | 466 | 51 | 15632 | 1249 |
Rab11fip1,Kdm5b,Errfi1,Mecp2,Mdm2,Acpp,Itpr1,Cd38,Lif,Icam1,Hif1a,Calcrl,Sphk1,Pdgfb,Scn1b,Mmp13,Inhba,Pde4b,Gja1,Hopx,Il1b,Hcar2,Ptger4,Zc3h12a,Hmox1,Ptgs2,Adora2b,Nr4a3,Ptafr,Edn1,Kcnj2,Il6,Pde5a,Flt1,Dock4,Htr2a,Atp2b4,Kat2b,Cx3cl1,Nr1h3,Slc9a1,Ednrb,Il10,Cav1,P2ry2,Nos2,Jak2,Cacna1d,Nlgn2,Cacnb3,Adrb2 |
| 1.331e-02 | -4.32 | GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | MSigDB lists | GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 466 | 51 | 15632 | 1249 |
Eno1,Hspa1a,Acpp,Txnrd1,Prdx5,Gsr,Mecp2,Pde1b,Rhoq,Pnp2,Cycs,Kmo,Calcrl,Upp1,Mthfr,Gda,Cnp,Pde4b,Txn1,Nampt,Pde7b,Hk2,Oas2,Adora2a,Ak4,Oas1g,Ldha,Cmpk2,Pgk1,Glrx,Il1b,Htr2b,Tet2,Pde5a,Papss2,Pgm1,Tpi1,Samhd1,Me1,Enpp4,Hk3,Pde3b,Pfkfb3,Slc25a25,Hk1,Eno2,Oas1a,Ampd3,Dck,Nox1,Pfkl |
| 1.331e-02 | -4.32 | sucrose degradation | BIOCYC pathways | MOUSE_PWY3DJ-5523 | 6 | 3 | 1025 | 97 |
Hk1,Hk2,Hk3 |
| 1.333e-02 | -4.32 | signal transduction by p53 class mediator | biological process | GO:0072331 | 76 | 11 | 20694 | 1406 |
Mdm2,Batf,Dyrk2,Sirt1,Casp2,Pml,Pmaip1,Cdkn1a,Ifi204,Nupr1,Ddit4 |
| 1.338e-02 | -4.31 | AP2_Q6 | MSigDB lists | AP2_Q6 | 236 | 29 | 15632 | 1249 |
Plagl2,Relb,Rab3ip,Apba1,Zfp513,Sdc1,Tmtc2,Spry2,Pde5a,Ass1,Crbn,Actb,Lhx2,Pcgf5,Smox,Cpeb4,Irf1,Med13,Pdgfb,Rab10,Sirt1,Nfkbid,Slc25a12,Mmd,Dcun1d3,Myadm,Cnp,Col11a2,Fzd5 |
| 1.339e-02 | -4.31 | AMUNDSON_RESPONSE_TO_ARSENITE | MSigDB lists | AMUNDSON_RESPONSE_TO_ARSENITE | 196 | 25 | 15632 | 1249 |
Prnp,Upp1,Atf3,Relb,Tap1,Me1,Ahsa1,Dnaja1,Tank,Ets2,Top3a,Mafg,Lyn,Dnajb4,Cpeb4,Ralgds,Asns,Junb,Maff,Wars,Mmd,St3gal5,Slc7a5,Trip13,Ext1 |
| 1.346e-02 | -4.31 | GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | MSigDB lists | GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | 216 | 27 | 15632 | 1249 |
Dek,Actb,Asf1a,H3f3b,Ifi204,Ifi211,Zfp36,Ifi208,Sirt1,Ifi203,Hat1,Jarid2,Arid4a,Klf2,Mov10,Mndal,Adar,Ifi207,Kat2b,Ifi214,Stat3,Mecp2,Aebp2,Ifi213,Ifi205,Hmga1,Ifi209 |
| 1.351e-02 | -4.30 | protein phosphatase type 1 complex | cellular component | GO:0000164 | 8 | 3 | 20747 | 1409 |
Ppp1r15a,Ppp1r15b,Nck1 |
| 1.351e-02 | -4.30 | perisynaptic space | cellular component | GO:0099544 | 8 | 3 | 20747 | 1409 |
Vcan,Tnc,Plat |
| 1.352e-02 | -4.30 | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 157 | 21 | 15632 | 1249 |
Dse,Samsn1,Serpine1,Mthfd1l,Gadd45b,Sdc2,Cxcl2,Pdpn,Slc44a1,Atxn7l1,Fcho2,Rnf145,Ptprj,Denr,Ldha,Nek6,Ppfibp1,Znrf1,Batf,Tnip1,Serpinb2 |
| 1.352e-02 | -4.30 | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_DN | MSigDB lists | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_DN | 157 | 21 | 15632 | 1249 |
Ubash3b,Dcp2,Pik3cd,Casp7,Cd38,Zhx2,Gfi1,Mdfic,Glrx,Tcf4,Rims3,Cenpe,Flt1,Tuba4a,Tagln,Mdm2,Ccng2,Dgka,Btg2,Sap30,Tnfsf8 |
| 1.352e-02 | -4.30 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_DN | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_DN | 157 | 21 | 15632 | 1249 |
Ccnj,Gsdmd,Bcl2l11,Ccne1,Parp14,Ube2l6,Psme2,Dennd1b,Oas1a,Oas2,Ch25h,Oas1g,Stat1,Dusp5,Lpar1,Phyh,Rcn1,Slco3a1,Pigv,Cd82,Fmnl2 |
| 1.352e-02 | -4.30 | GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP | MSigDB lists | GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP | 119 | 17 | 15632 | 1249 |
Dock10,Il18rap,Arhgap26,Pdpn,Irf4,Zc3h7a,Ttc39c,Dpy19l1,Spn,Cd80,Osbpl3,Adrb2,Xrn1,Azi2,Mmp25,Dgkh,Itga4 |
| 1.352e-02 | -4.30 | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP | MSigDB lists | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP | 119 | 17 | 15632 | 1249 |
Lrrc8c,Slc16a1,Adam19,Tpx2,Nsmaf,Kif3c,Mthfd2,Grina,Pttg1,Larp1,Slc39a14,St3gal5,Tgs1,Ksr1,Cenpe,Gramd1a,Flt1 |
| 1.352e-02 | -4.30 | GO_POSITIVE_REGULATION_OF_BINDING | MSigDB lists | GO_POSITIVE_REGULATION_OF_BINDING | 119 | 17 | 15632 | 1249 |
Trib3,Kat2b,Mmp9,Plaur,Jak2,Plcl2,Bambi,Bmp2,Cav1,Plk2,Traf2,Eno1,Txn1,Crbn,Rapgef2,Csf3,Irf4 |
| 1.352e-02 | -4.30 | PTEN_DN.V2_UP | MSigDB lists | PTEN_DN.V2_UP | 119 | 17 | 15632 | 1249 |
Lcn2,P2ry2,Casp4,Jun,Cd86,Birc3,Pcx,Csf1,Il4ra,Rnd1,Ptgs2,Dennd2a,Rtn1,Il1b,Agpat4,Lipg,Plau |
| 1.353e-02 | -4.30 | positive regulation of cardiac epithelial to mesenchymal transition | biological process | GO:0062043 | 8 | 3 | 20694 | 1406 |
Jag1,Notch1,Acvr1 |
| 1.353e-02 | -4.30 | positive regulation of glomerular mesangial cell proliferation | biological process | GO:0072126 | 8 | 3 | 20694 | 1406 |
Cflar,Pdgfb,Egr1 |
| 1.353e-02 | -4.30 | endothelial cell activation | biological process | GO:0042118 | 8 | 3 | 20694 | 1406 |
Acvrl1,Cxcl10,Tcf4 |
| 1.353e-02 | -4.30 | regulation of artery morphogenesis | biological process | GO:1905651 | 8 | 3 | 20694 | 1406 |
Ptger4,Akt3,Notch1 |
| 1.353e-02 | -4.30 | stress response to metal ion | biological process | GO:0097501 | 8 | 3 | 20694 | 1406 |
Slc30a1,Mt1,Mt2 |
| 1.353e-02 | -4.30 | L-aspartate transmembrane transport | biological process | GO:0070778 | 8 | 3 | 20694 | 1406 |
Slc13a3,Slc25a12,Slc25a22 |
| 1.353e-02 | -4.30 | positive regulation of NK T cell activation | biological process | GO:0051135 | 8 | 3 | 20694 | 1406 |
Hsph1,Il18,Il12b |
| 1.353e-02 | -4.30 | response to interleukin-15 | biological process | GO:0070672 | 8 | 3 | 20694 | 1406 |
Il15,Il2rg,Il15ra |
| 1.353e-02 | -4.30 | type 2 immune response | biological process | GO:0042092 | 8 | 3 | 20694 | 1406 |
Bcl6,Batf,Dennd1b |
| 1.353e-02 | -4.30 | regulation of chemokine (C-C motif) ligand 5 production | biological process | GO:0071649 | 8 | 3 | 20694 | 1406 |
Mul1,Mcoln2,Arg2 |
| 1.353e-02 | -4.30 | positive regulation of interleukin-12 biosynthetic process | biological process | GO:0045084 | 8 | 3 | 20694 | 1406 |
Irf1,Tlr6,Rel |
| 1.353e-02 | -4.30 | epithelial fluid transport | biological process | GO:0042045 | 8 | 3 | 20694 | 1406 |
Edn1,Itpr1,Ednrb |
| 1.353e-02 | -4.30 | positive regulation of apoptotic process involved in morphogenesis | biological process | GO:1902339 | 8 | 3 | 20694 | 1406 |
Notch1,Tnfrsf1b,Pml |
| 1.353e-02 | -4.30 | lactate transmembrane transport | biological process | GO:0035873 | 8 | 3 | 20694 | 1406 |
Slc16a3,Myc,Slc16a1 |
| 1.353e-02 | -4.30 | regulation of extracellular matrix assembly | biological process | GO:1901201 | 8 | 3 | 20694 | 1406 |
Rgcc,Notch1,Antxr1 |
| 1.353e-02 | -4.30 | positive regulation of apoptotic process involved in development | biological process | GO:1904747 | 8 | 3 | 20694 | 1406 |
Pml,Notch1,Tnfrsf1b |
| 1.353e-02 | -4.30 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline | biological process | GO:0018401 | 8 | 3 | 20694 | 1406 |
P4ha1,P4ha2,Egln3 |
| 1.353e-02 | -4.30 | skeletal muscle acetylcholine-gated channel clustering | biological process | GO:0071340 | 8 | 3 | 20694 | 1406 |
Agrn,Etv5,Lrp4 |
| 1.353e-02 | -4.30 | detoxification of inorganic compound | biological process | GO:0061687 | 8 | 3 | 20694 | 1406 |
Mt2,Slc30a1,Mt1 |
| 1.353e-02 | -4.30 | peptidyl-lysine hydroxylation | biological process | GO:0017185 | 8 | 3 | 20694 | 1406 |
Plod3,Jmjd6,Plod2 |
| 1.353e-02 | -4.30 | regulation of interleukin-17 secretion | biological process | GO:1905076 | 8 | 3 | 20694 | 1406 |
Arid5a,Arg2,Osm |
| 1.353e-02 | -4.30 | positive regulation of T-helper 1 cell differentiation | biological process | GO:0045627 | 8 | 3 | 20694 | 1406 |
Irf1,Ripk2,Hlx |
| 1.353e-02 | -4.30 | regulation of mast cell chemotaxis | biological process | GO:0060753 | 8 | 3 | 20694 | 1406 |
Swap70,Ccl5,Vegfc |
| 1.353e-02 | -4.30 | positive regulation of tumor necrosis factor-mediated signaling pathway | biological process | GO:1903265 | 8 | 3 | 20694 | 1406 |
Casp4,Casp1,Traf2 |
| 1.353e-02 | -4.30 | lactate transport | biological process | GO:0015727 | 8 | 3 | 20694 | 1406 |
Myc,Slc16a1,Slc16a3 |
| 1.353e-02 | -4.30 | regulation of neutrophil degranulation | biological process | GO:0043313 | 8 | 3 | 20694 | 1406 |
Ptafr,Syk,Abr |
| 1.356e-02 | -4.30 | SPRY | pfam domains | PF00622 | 72 | 11 | 18711 | 1348 |
Spryd7,Trim21,Trim30d,Trim26,Rnf135,Trim14,Trim34a,Spsb1,Trim12c,Mid1,Trim30a |
| 1.362e-02 | -4.30 | endopeptidase regulator activity | molecular function | GO:0061135 | 203 | 23 | 20217 | 1400 |
Serpinb6b,Spint2,Psme1,Timp1,Prdx5,Serpina3g,Birc2,Wfdc17,Pttg1,Serpine1,Tnfsf14,Crim1,Psme2,Serpinb9b,Ctla2b,Serpinb2,C3,Birc3,Slpi,Serpinb9,Cst7,Bcl2a1d,Serpina3f |
| 1.368e-02 | -4.29 | LANDIS_ERBB2_BREAST_TUMORS_324_DN | MSigDB lists | LANDIS_ERBB2_BREAST_TUMORS_324_DN | 138 | 19 | 15632 | 1249 |
Plac8,Phldb1,Gja1,Alas1,Htra1,H2-Aa,Ppp2r5a,Col18a1,Nkiras1,Tgfbi,Phyh,Gbe1,Papss2,Acsl1,Nr1h3,St3gal6,Gpd2,Cd34,Ptges |
| 1.368e-02 | -4.29 | GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_UP | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_UP | 138 | 19 | 15632 | 1249 |
Tpst1,Spsb1,Parp8,Gramd1a,Treml2,Oas2,Bcl9,Tlr1,Slc44a1,Ampd3,Parp11,Usp18,Ppm1l,Ddx60,Slfn5,Sp110,Herc3,Znrf1,Ikbke |
| 1.368e-02 | -4.29 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_1H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_1H_DN | 138 | 19 | 15632 | 1249 |
Gadd45b,Nampt,Pde4b,Osm,Gem,Tiparp,Serpine1,Fosb,Plod2,Peli1,Fabp7,Csrnp1,Kdm6b,Rnd1,Traf1,Irs2,Map3k8,Ptgs2,Nfkb2 |
| 1.371e-02 | -4.29 | ATPase-coupled peptide transmembrane transporter activity | molecular function | GO:0015440 | 3 | 2 | 20217 | 1400 |
Tap1,Tap2 |
| 1.371e-02 | -4.29 | CXCR3 chemokine receptor binding | molecular function | GO:0048248 | 3 | 2 | 20217 | 1400 |
Cxcl10,Pf4 |
| 1.371e-02 | -4.29 | Toll-like receptor 2 binding | molecular function | GO:0035663 | 3 | 2 | 20217 | 1400 |
Tlr6,Tlr1 |
| 1.371e-02 | -4.29 | interleukin-27 receptor binding | molecular function | GO:0045523 | 3 | 2 | 20217 | 1400 |
Il27,Ebi3 |
| 1.371e-02 | -4.29 | ATPase-coupled xenobiotic transmembrane transporter activity | molecular function | GO:0008559 | 3 | 2 | 20217 | 1400 |
Abcb1a,Abcc1 |
| 1.371e-02 | -4.29 | macrophage colony-stimulating factor receptor binding | molecular function | GO:0005157 | 3 | 2 | 20217 | 1400 |
Stap1,Csf1 |
| 1.371e-02 | -4.29 | sphingolipid floppase activity | molecular function | GO:0046623 | 3 | 2 | 20217 | 1400 |
Abcb1a,Abcc1 |
| 1.371e-02 | -4.29 | CCR1 chemokine receptor binding | molecular function | GO:0031726 | 3 | 2 | 20217 | 1400 |
Ccl5,Ccl4 |
| 1.371e-02 | -4.29 | interleukin-15 receptor activity | molecular function | GO:0042010 | 3 | 2 | 20217 | 1400 |
Il15ra,Il2rg |
| 1.371e-02 | -4.29 | 5'-3' exoribonuclease activity | molecular function | GO:0004534 | 3 | 2 | 20217 | 1400 |
Dcp2,Xrn1 |
| 1.371e-02 | -4.29 | procollagen-lysine 5-dioxygenase activity | molecular function | GO:0008475 | 3 | 2 | 20217 | 1400 |
Plod2,Plod3 |
| 1.379e-02 | -4.28 | GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | MSigDB lists | GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | 167 | 22 | 15632 | 1249 |
Clec4e,Htr2a,Olr1,Magohb,Ptger4,St3gal6,Asb13,Frmd4a,Ms4a6d,Irgq,Syne2,Zfp324,Mecp2,Slc7a11,Slc25a37,Slc4a7,Slc12a9,Fosb,Dock4,Golga3,Klhl25,Mcm9 |
| 1.379e-02 | -4.28 | GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_DN | MSigDB lists | GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_DN | 167 | 22 | 15632 | 1249 |
Cd83,Cldnd1,Trib1,Sell,Map3k8,Ptprj,Zc3h12a,Oasl1,Hivep3,Taf4b,Maff,Sat1,Cycs,Alas1,Lrch1,Mrpl52,Samsn1,Il10,Adap2,Nampt,Lipe,Fcgr4 |
| 1.382e-02 | -4.28 | AGGGCCA_MIR328 | MSigDB lists | AGGGCCA_MIR328 | 74 | 12 | 15632 | 1249 |
Fam133b,Pim1,Arid5a,Slc2a1,Max,Itga5,St3gal3,Mecp2,Etv6,Hap1,Nrp2,Nr3c1 |
| 1.382e-02 | -4.28 | p53-Independent G1/S DNA damage checkpoint | REACTOME pathways | R-MMU-69613 | 52 | 10 | 8608 | 757 |
Psmb10,Atm,Psmb9,Psmb8,Psme2b,Psmd10,Psme1,Psma6,Psmb6,Psme2 |
| 1.382e-02 | -4.28 | Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | REACTOME pathways | R-MMU-69601 | 52 | 10 | 8608 | 757 |
Psmb8,Psmb9,Atm,Psmb10,Psme2,Psmb6,Psma6,Psme1,Psmd10,Psme2b |
| 1.382e-02 | -4.28 | p53-Independent DNA Damage Response | REACTOME pathways | R-MMU-69610 | 52 | 10 | 8608 | 757 |
Psme2,Psmb6,Psma6,Psme1,Psmd10,Psme2b,Psmb8,Psmb9,Atm,Psmb10 |
| 1.383e-02 | -4.28 | GNF2_HDAC1 | MSigDB lists | GNF2_HDAC1 | 110 | 16 | 15632 | 1249 |
Ifi205,Mndal,Ifi209,Psmb8,Ifi213,Ifi203,Tapbp,Tra2a,Hdac1,Psme2,Ifi208,Ifi211,Fam111a,Ifi214,Ifi204,Ifi207 |
| 1.384e-02 | -4.28 | GO_ESTABLISHMENT_OR_MAINTENANCE_OF_BIPOLAR_CELL_POLARITY | MSigDB lists | GO_ESTABLISHMENT_OR_MAINTENANCE_OF_BIPOLAR_CELL_POLARITY | 33 | 7 | 15632 | 1249 |
Lhx2,Mark2,Arf4,Fscn1,Clic4,Pdzd11,Ezr |
| 1.384e-02 | -4.28 | GO_AXO_DENDRITIC_TRANSPORT | MSigDB lists | GO_AXO_DENDRITIC_TRANSPORT | 33 | 7 | 15632 | 1249 |
Uchl1,Apba1,Hif1a,Rab21,Ap3b1,Ap3m2,Hap1 |
| 1.384e-02 | -4.28 | FUJII_YBX1_TARGETS_UP | MSigDB lists | FUJII_YBX1_TARGETS_UP | 33 | 7 | 15632 | 1249 |
Slc16a3,Ccl5,Nlrc5,Fas,Mvp,Cdkn1a,Wars |
| 1.384e-02 | -4.28 | VALK_AML_CLUSTER_5 | MSigDB lists | VALK_AML_CLUSTER_5 | 33 | 7 | 15632 | 1249 |
Ptafr,Vcan,Cd86,Nod2,Slc15a3,Ccr1,Pilra |
| 1.384e-02 | -4.28 | REACTOME_G1_PHASE | MSigDB lists | REACTOME_G1_PHASE | 33 | 7 | 15632 | 1249 |
Cdkn2d,Ccnd2,Ppp2r1b,Cdkn1a,Rbl1,Ppp2r2a,Ccnd1 |
| 1.384e-02 | -4.28 | KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM | MSigDB lists | KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM | 33 | 7 | 15632 | 1249 |
Hk1,Tpi1,Gmppb,Pfkfb3,Hk2,Pfkl,Hk3 |
| 1.384e-02 | -4.28 | GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | 33 | 7 | 15632 | 1249 |
Il12b,Cav1,Trib1,Ptgir,Hmox1,Tnfaip3,Il15 |
| 1.387e-02 | -4.28 | negative regulation of binding | biological process | GO:0051100 | 173 | 20 | 20694 | 1406 |
Hmox1,Jun,Cav1,Ifit2,Dnajb2,Jak2,Mecp2,Slpi,Pdgfb,Pim2,Il10,Actb,Plscr1,Sirt1,Met,Mitd1,Itga4,Myc,Lhx2,Adrb2 |
| 1.392e-02 | -4.27 | IFabd | smart domains | SM00076 | 24 | 6 | 9567 | 823 |
Ifnb1,Ifna1,Ifna5,Ifna2,Ifna6,Ifna4 |
| 1.394e-02 | -4.27 | BUDHU_LIVER_CANCER_METASTASIS_UP | MSigDB lists | BUDHU_LIVER_CANCER_METASTASIS_UP | 7 | 3 | 15632 | 1249 |
Il10,Csf1,Il15 |
| 1.394e-02 | -4.27 | GO_PHOSPHATASE_ACTIVATOR_ACTIVITY | MSigDB lists | GO_PHOSPHATASE_ACTIVATOR_ACTIVITY | 7 | 3 | 15632 | 1249 |
Bmp2,Ppp1r15a,Phactr4 |
| 1.394e-02 | -4.27 | RAY_ALZHEIMERS_DISEASE | MSigDB lists | RAY_ALZHEIMERS_DISEASE | 7 | 3 | 15632 | 1249 |
Ccl5,Tnf,Il1a |
| 1.394e-02 | -4.27 | GO_REGULATION_OF_INTERLEUKIN_10_SECRETION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_10_SECRETION | 7 | 3 | 15632 | 1249 |
Cd274,Ptger4,H2-Eb1 |
| 1.394e-02 | -4.27 | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_DN | MSigDB lists | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_DN | 7 | 3 | 15632 | 1249 |
Egln3,Atm,Casp7 |
| 1.394e-02 | -4.27 | TAKADA_GASTRIC_CANCER_COPY_NUMBER_UP | MSigDB lists | TAKADA_GASTRIC_CANCER_COPY_NUMBER_UP | 7 | 3 | 15632 | 1249 |
Met,Sdc1,Myc |
| 1.394e-02 | -4.27 | GO_ACID_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_ACID_PHOSPHATASE_ACTIVITY | 7 | 3 | 15632 | 1249 |
Acp2,Acpp,Minpp1 |
| 1.394e-02 | -4.27 | BUSA_SAM68_TARGETS_UP | MSigDB lists | BUSA_SAM68_TARGETS_UP | 7 | 3 | 15632 | 1249 |
Nr4a1,Nr3c1,Ccnd1 |
| 1.394e-02 | -4.27 | ZEILSTRA_CD44_TARGETS_DN | MSigDB lists | ZEILSTRA_CD44_TARGETS_DN | 7 | 3 | 15632 | 1249 |
Daxx,Cflar,Casp1 |
| 1.394e-02 | -4.27 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | MSigDB lists | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | 7 | 3 | 15632 | 1249 |
Akt3,Phlpp1,Trib3 |
| 1.396e-02 | -4.27 | POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN | MSigDB lists | POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN | 57 | 10 | 15632 | 1249 |
Vcan,Rnd3,Gcnt2,Irf8,Cyfip1,Ptch1,Tcf4,Lmo4,Uchl1,Ltbp2 |
| 1.396e-02 | -4.27 | GO_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | 57 | 10 | 15632 | 1249 |
Hsph1,Lrp8,Ccl5,Cav1,Ptpn2,Pdgfb,Rap2c,Stap1,Errfi1,Mvp |
| 1.396e-02 | -4.27 | PID_FGF_PATHWAY | MSigDB lists | PID_FGF_PATHWAY | 57 | 10 | 15632 | 1249 |
Plau,Spry2,Met,Plaur,Sdc2,Mmp9,Stat1,Src,Jun,Fos |
| 1.396e-02 | -4.27 | GO_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS | 57 | 10 | 15632 | 1249 |
Col18a1,Cd40,Serpine1,Il10,Icam1,Il6,Kdr,Thbs1,Angpt1,Tnfaip3 |
| 1.396e-02 | -4.27 | GO_POSITIVE_REGULATION_OF_INSULIN_SECRETION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INSULIN_SECRETION | 57 | 10 | 15632 | 1249 |
Gpr68,Nlgn2,Cd38,Prkce,Jak2,Serp1,Irs2,Hif1a,Gja1,H2-Eb1 |
| 1.398e-02 | -4.27 | extrinsic component of cytoplasmic side of plasma membrane | cellular component | GO:0031234 | 97 | 13 | 20747 | 1409 |
Fgr,Cyth3,Src,Gng4,Gna15,Errfi1,Gng12,Gramd1a,Hck,Lyn,Gng11,Rgs1,Gnb4 |
| 1.398e-02 | -4.27 | actomyosin | cellular component | GO:0042641 | 97 | 13 | 20747 | 1409 |
Micall2,Daam1,Kat2b,Palld,Cnn2,Tpm4,Flnb,Zyx,Dst,Fscn1,Ptk2,Pdlim7,Actb |
| 1.399e-02 | -4.27 | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP | 177 | 23 | 15632 | 1249 |
Nfxl1,Slfn9,Gng12,Pf4,Prkar2b,Kpna3,Tlr3,Rac3,Ms4a6d,Clec4d,Rnf19a,Rnf14,Sgcb,Nod1,Lpcat2,Apaf1,Cd180,Slfn8,Tnc,Hspa2,Triobp,Gramd1a,P2ry13 |
| 1.399e-02 | -4.27 | GSE27786_BCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_BCELL_VS_ERYTHROBLAST_UP | 177 | 23 | 15632 | 1249 |
Bcl2a1a,Dusp16,Socs7,Traf3ip2,Ttc39b,Med13,Zfp36,Leng9,Tap2,Lmo4,Osm,Sik3,Ikzf1,Stard5,Ubtd2,Cox17,Ap3b1,Bcl2a1d,Tapbp,Klf6,Bcl2a1b,Ptpn2,Cited2 |
| 1.399e-02 | -4.27 | GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN | 177 | 23 | 15632 | 1249 |
Nrp2,Stxbp3,Ccrl2,Birc3,Rnaset2a,Rnaset2b,Ppfibp2,Filip1l,Ak4,Tlr2,D1Ertd622e,Cish,B3gnt5,Morc3,Fam43a,Klhl25,Lpcat2,Cd38,Slfn5,Nfkbiz,Ddx58,Cx3cl1,Rtp4 |
| 1.399e-02 | -4.27 | GSE2706_2H_VS_8H_LPS_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_LPS_STIM_DC_UP | 177 | 23 | 15632 | 1249 |
Hvcn1,Pgm1,Nkiras1,Stxbp1,Lif,Egr1,Nfkbiz,Stx11,Maff,Jag1,Arl5b,Btg2,Lcp2,Cacybp,Ppp1r15a,Slc12a9,Plek,Adrb2,Ier3,Pdzd11,Adora2b,Zc3h12a,Egr3 |
| 1.399e-02 | -4.27 | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN | MSigDB lists | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN | 177 | 23 | 15632 | 1249 |
Gnb4,Mdfic,Myo10,Tmem176b,Prnp,Cenpe,Ass1,Gypc,Ets2,Gpsm2,Sh3bgrl2,Plcl2,Gng12,Pkp4,Frmd6,Snn,Rcn1,Slc25a22,Bcl9,Ampd3,Slpi,Ube2e2,Rasgrp1 |
| 1.399e-02 | -4.27 | GSE7852_LN_VS_THYMUS_TCONV_DN | MSigDB lists | GSE7852_LN_VS_THYMUS_TCONV_DN | 177 | 23 | 15632 | 1249 |
Smc5,Fam102b,Prkar2b,Frmd6,Txn1,Eno2,Rnf14,Timeless,Rap1gap2,Mcm10,Ppm1l,Sass6,Rras2,Cenpe,Ctsc,Irgq,Fut8,Dbnl,Vcan,Lztfl1,Cept1,Atp13a1,Pde5a |
| 1.399e-02 | -4.27 | GSE2128_C57BL6_VS_NOD_THYMOCYTE_UP | MSigDB lists | GSE2128_C57BL6_VS_NOD_THYMOCYTE_UP | 177 | 23 | 15632 | 1249 |
Ccl4,5430427O19Rik,Stard7,Smc5,Scyl2,Kpna3,Sap30,Sirt1,Tnfrsf1b,Ccne1,Cenpj,Gbp7,Cd86,Lrp8,Rars,Mxd1,Nmral1,Kdm4a,Ccnd2,Gsr,Mlkl,Fgl2,Eno1 |
| 1.399e-02 | -4.27 | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_DN | 177 | 23 | 15632 | 1249 |
Gmppb,Prdx1,Gbp2,Crim1,Bcl2a1b,Ppp1r14b,Homer1,Ccdc86,Rab11fip1,Kcnj2,Bcl2a1d,Cd200,Ptk2,Osbpl3,Bcl2a1a,Nfxl1,Keap1,Mob3c,Gem,Cacybp,Lcp2,Phlda1,Stx6 |
| 1.399e-02 | -4.27 | GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_UP | MSigDB lists | GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_UP | 177 | 23 | 15632 | 1249 |
Jdp2,Fam43a,Bcl6,Dock4,Lmo4,Irf8,Tnfsf14,Tnc,Egln3,Stx11,Rnf19a,Mmd,Mapkapk2,Hmox1,Stxbp1,Hhex,Cdk5r1,Mafg,Ak4,Ppp2r1b,Cd80,Jak2,Fam162a |
| 1.399e-02 | -4.27 | GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_DN | MSigDB lists | GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_DN | 177 | 23 | 15632 | 1249 |
Irgq,Fgl2,Mmd,Bcl2a1d,Pcx,Tor3a,Txn1,Agrn,Bcl2a1b,Srm,Nod1,Herc3,Bcl2a1a,Cd300lf,Mob3c,Ppfibp2,Il15ra,Ahr,Dnase1l3,Mcm10,Mxd1,Tpx2,St3gal6 |
| 1.402e-02 | -4.27 | peptidyl-tyrosine dephosphorylation | biological process | GO:0035335 | 97 | 13 | 20694 | 1406 |
Mtmr14,Dusp28,Dusp2,Ptprj,Dusp8,Eya4,Dusp14,Dusp4,Ubash3b,Dusp5,Dusp1,Dusp6,Ptpn2 |
| 1.404e-02 | -4.27 | - | gene3d domains | 2.30.29.30 | 398 | 47 | 8819 | 755 |
Ezr,Apba1,Vasp,Dgkh,Dcp1a,Rgs3,Cyth3,Spred3,Triobp,Evl,Swap70,Gramd1a,Plekha4,Akt3,Dock10,Plekhg1,Spred1,Plekha2,Osbpl3,Plek,Ptk2,Arhgap26,Irs2,Plekhf2,Phldb1,Tbc1d1,Homer1,Myo10,Phlpp1,Arhgef3,Fam43a,Pid1,Plekhn1,Plcl2,Ranbp2,Asap3,Psd4,Phlpp2,Psd,Adap2,Plekha5,Spata13,Carmil1,Frmd4a,Frmd6,Stap1,Grk3 |
| 1.408e-02 | -4.26 | sprouting angiogenesis | biological process | GO:0002040 | 57 | 9 | 20694 | 1406 |
Kdr,Flt1,Egr3,Angpt1,Thbs1,Vegfc,Nr4a1,Notch1,Jmjd6 |
| 1.409e-02 | -4.26 | KEGG_ECM_RECEPTOR_INTERACTION | MSigDB lists | KEGG_ECM_RECEPTOR_INTERACTION | 83 | 13 | 15632 | 1249 |
Col11a2,Agrn,Itgav,Sdc2,Itgb8,Tnc,Sdc1,Itga9,Itga5,Itga4,Thbs1,Sdc4,Col4a2 |
| 1.409e-02 | -4.26 | GO_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION | MSigDB lists | GO_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION | 83 | 13 | 15632 | 1249 |
Hif1a,Irs2,Ptger4,Lif,Cd38,Nlgn2,Jak2,Serp1,H2-Eb1,S100a8,Gja1,Gpr68,Prkce |
| 1.410e-02 | -4.26 | positive regulation of interleukin-6 secretion | biological process | GO:2000778 | 30 | 6 | 20694 | 1406 |
Ifih1,Lgals9,Arid5a,Ddx58,Il1b,Tnf |
| 1.410e-02 | -4.26 | positive regulation of leukocyte degranulation | biological process | GO:0043302 | 30 | 6 | 20694 | 1406 |
Adora2b,Fgr,Il4ra,Syk,Stxbp1,Ptafr |
| 1.410e-02 | -4.26 | negative regulation of cytokine biosynthetic process | biological process | GO:0042036 | 30 | 6 | 20694 | 1406 |
Il6,Nfkb1,Il10,Nmi,Errfi1,Zfp36 |
| 1.410e-02 | -4.26 | lymph node development | biological process | GO:0048535 | 30 | 6 | 20694 | 1406 |
Ripk3,Il15,Pdpn,Nfkb1,Ikzf1,Nfkb2 |
| 1.410e-02 | -4.26 | regulation of interleukin-4 production | biological process | GO:0032673 | 30 | 6 | 20694 | 1406 |
Syk,Icosl,Irf4,Tnfsf4,Cd83,Nlrp3 |
| 1.410e-02 | -4.26 | positive regulation of syncytium formation by plasma membrane fusion | biological process | GO:0060143 | 30 | 6 | 20694 | 1406 |
Ccl8,Gdf15,Cxcl9,Ehd1,Il4ra,Tnfsf14 |
| 1.410e-02 | -4.26 | negative regulation of nervous system process | biological process | GO:0031645 | 30 | 6 | 20694 | 1406 |
Tnf,Gpr35,Ctsc,Cacnb3,Il10,S1pr2 |
| 1.411e-02 | -4.26 | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | MSigDB lists | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | 148 | 20 | 15632 | 1249 |
Nfkbid,Ncoa5,Edn1,Btg2,Zfp36,Tnfsf8,Egr2,Klf2,Gadd45b,Pik3r5,Il1b,Cd83,Slco3a1,Irs2,Ptger4,Egr3,Sema4c,Dyrk2,Rnf139,Bcor |
| 1.413e-02 | -4.26 | mouse chr9|9 E2 | chromosome location | mouse chr9|9 E2 | 9 | 3 | 24173 | 1464 |
Sh3bgrl2,Phip,Hmgn3 |
| 1.413e-02 | -4.26 | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN | MSigDB lists | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN | 187 | 24 | 15632 | 1249 |
Tulp3,Sell,Slco3a1,Aff1,Rab3ip,Enpp4,Sgk3,Rras2,Acpp,Gpr18,Spsb1,Treml2,Acvrl1,Gbp9,Gbp4,Asb13,Spata5l1,Gpd2,Dyrk2,Oasl1,Lmo4,4930523C07Rik,Card6,Cnn3 |
| 1.413e-02 | -4.26 | GSE18893_TCONV_VS_TREG_24H_CULTURE_UP | MSigDB lists | GSE18893_TCONV_VS_TREG_24H_CULTURE_UP | 187 | 24 | 15632 | 1249 |
Itpr1,Klhl25,Ppp1r14b,Ass1,Glipr2,Cyth3,Tle3,Cd80,Sipa1l1,Igsf8,Lcp2,Cd274,Myadm,Tnfrsf1b,Rap1gap2,Adora2a,Slamf9,Plscr1,Nrp2,Tmeff1,Ptger4,Snn,Plaur,Prkx |
| 1.413e-02 | -4.26 | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_UNSTIM_MACROPHAGE_DN | MSigDB lists | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_UNSTIM_MACROPHAGE_DN | 187 | 24 | 15632 | 1249 |
Lrp4,Pik3r5,N4bp1,Plac8,Klf6,Map3k6,Swap70,Micall2,Cpd,Cebpd,Rin2,Hlx,Tmem176b,Nlrp3,Tulp3,Gja1,Jarid2,Gem,Etv6,Zc3h12a,Rac3,Cpeb4,Smox,Plaur |
| 1.413e-02 | -4.26 | GSE18893_CTRL_VS_TNF_TREATED_TCONV_24H_DN | MSigDB lists | GSE18893_CTRL_VS_TNF_TREATED_TCONV_24H_DN | 187 | 24 | 15632 | 1249 |
Bcl2a1b,Bcl2a1d,Cept1,Ogfrl1,Ap3b1,Batf2,Plk3,Clcn5,1600014C10Rik,Cdc42ep2,Cenpj,Fzd5,Pid1,Pde4b,Igsf9,Junb,Nfkbid,Arl5b,Bcorl1,Chic2,Dgkh,Ap3m2,Lrrc8c,Bcl2a1a |
| 1.413e-02 | -4.26 | GSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_DN | MSigDB lists | GSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_DN | 187 | 24 | 15632 | 1249 |
Ell2,Slc31a1,Socs3,Lox,Tgfbi,Cacnb3,Ms4a6d,Pfkl,S100a8,Cnn3,Rhou,Gbp3,Sphk1,Tspo,Fcgr1,Plau,Rbms2,Prpf38a,Bcl2l11,Ccdc86,Tnc,Sat1,Abcb1a,Rin2 |
| 1.413e-02 | -4.26 | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP | MSigDB lists | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP | 187 | 24 | 15632 | 1249 |
Hk2,Zfp36,Plscr1,Rcn1,Mafg,Slc31a1,Stip1,Rcl1,Idi1,Ets2,Dnaja1,D1Ertd622e,Tor1aip2,Il4i1,Dusp2,Cdk5r1,Jmjd6,Irs2,Ch25h,Marcksl1,Ier2,Aff1,Prpf38a,Prdx1 |
| 1.415e-02 | -4.26 | Transcriptional Regulation by TP53 | REACTOME pathways | R-MMU-3700989 | 263 | 34 | 8608 | 757 |
Tmem219,Btg2,Mdm2,Gsr,Cdk5r1,Rffl,Cnot4,Kmt5a,Daxx,Taf4b,Plk2,Tpx2,Rbbp8,Txnrd1,Tnks1bp1,Hdac1,Pml,Txn1,Cdkn1a,Plk3,Top3a,Casp2,Rnf34,Rictor,Ccne1,Tcea1,Polr2g,Ddit4,Dyrk2,Prdx5,Atm,Ppp2r1b,Cenpj,Prdx1 |
| 1.420e-02 | -4.25 | IVANOVA_HEMATOPOIESIS_STEM_CELL | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL | 227 | 28 | 15632 | 1249 |
Egr1,Col18a1,Ifih1,Sdc1,Etv3,Myo10,Bcl2l11,Nfkbia,Nr4a1,Tcf4,Jun,Ifi44,Prkce,Cxcl14,Dusp4,Nfkbie,Smc5,Dusp5,Sema4c,Itga9,Trafd1,Ppfibp2,Pde4b,Gem,Zc3h12c,Rilpl1,Ddit4,Maff |
| 1.425e-02 | -4.25 | RAO_BOUND_BY_SALL4 | MSigDB lists | RAO_BOUND_BY_SALL4 | 207 | 26 | 15632 | 1249 |
Dgkh,Max,Ttc39b,Gcnt2,Whamm,Vegfc,Map4k4,Gja1,Dusp6,Jarid2,Asns,Klf2,Cacybp,Tmeff1,Slc39a14,Upp1,Smg7,Col4a2,Zc3hav1,Pdgfc,Spred1,Flrt3,Spic,Slc44a1,Spry2,Aebp2 |
| 1.425e-02 | -4.25 | immunoglobulin receptor activity | molecular function | GO:0019763 | 8 | 3 | 20217 | 1400 |
Fcgr2b,Fcgr1,Fcgr4 |
| 1.425e-02 | -4.25 | IgG binding | molecular function | GO:0019864 | 8 | 3 | 20217 | 1400 |
Fcgr2b,Fcgr1,Fcgr4 |
| 1.425e-02 | -4.25 | vascular endothelial growth factor binding | molecular function | GO:0038085 | 8 | 3 | 20217 | 1400 |
Flt1,Kdr,Pdgfrb |
| 1.425e-02 | -4.25 | peptidyl-proline 4-dioxygenase activity | molecular function | GO:0031545 | 8 | 3 | 20217 | 1400 |
P4ha1,P4ha2,Egln3 |
| 1.425e-02 | -4.25 | RAGE receptor binding | molecular function | GO:0050786 | 8 | 3 | 20217 | 1400 |
S100a8,Fpr1,Fpr2 |
| 1.429e-02 | -4.25 | SPRY_dom | interpro domains | IPR003877 | 73 | 11 | 19984 | 1430 |
Trim30a,Trim14,Trim26,Trim21,Rnf135,Trim34a,Spsb1,Trim30d,Spryd7,Mid1,Trim12c |
| 1.431e-02 | -4.25 | regulation of endothelial cell chemotaxis | biological process | GO:2001026 | 22 | 5 | 20694 | 1406 |
Notch1,Met,Kdr,Pdgfb,Thbs1 |
| 1.431e-02 | -4.25 | response to fluid shear stress | biological process | GO:0034405 | 22 | 5 | 20694 | 1406 |
Ass1,Src,Ptgs2,Cited2,Klf2 |
| 1.431e-02 | -4.25 | regulation of membrane protein ectodomain proteolysis | biological process | GO:0051043 | 22 | 5 | 20694 | 1406 |
Il10,Timp1,Tnfrsf1b,Tnf,Il1b |
| 1.431e-02 | -4.25 | regulation of metanephros development | biological process | GO:0072215 | 22 | 5 | 20694 | 1406 |
Myc,Lif,Pdgfb,Pdgfrb,Egr1 |
| 1.431e-02 | -4.25 | regulation of icosanoid secretion | biological process | GO:0032303 | 22 | 5 | 20694 | 1406 |
P2ry2,Il1a,Il1b,Edn1,Syk |
| 1.431e-02 | -4.25 | zinc ion transmembrane transport | biological process | GO:0071577 | 22 | 5 | 20694 | 1406 |
Slc39a4,Slc39a14,Slc39a13,Slc30a4,Slc30a1 |
| 1.431e-02 | -4.25 | positive regulation of tumor necrosis factor secretion | biological process | GO:1904469 | 22 | 5 | 20694 | 1406 |
Ifih1,Tlr2,Ddx58,Arid5a,Fzd5 |
| 1.431e-02 | -4.25 | regulation of protein homooligomerization | biological process | GO:0032462 | 22 | 5 | 20694 | 1406 |
Src,Bcl2l11,Fas,Rhoc,Crbn |
| 1.431e-02 | -4.25 | regulation of vascular endothelial cell proliferation | biological process | GO:1905562 | 22 | 5 | 20694 | 1406 |
Flt1,Ccl12,Stat3,Itga4,Akt3 |
| 1.431e-02 | -4.25 | macrophage differentiation | biological process | GO:0030225 | 22 | 5 | 20694 | 1406 |
Casp8,Sirt1,Tlr2,Il15,Csf1 |
| 1.431e-02 | -4.25 | nitrogen compound transport | biological process | GO:0071705 | 1535 | 126 | 20694 | 1406 |
Kif5c,Abcb1a,Mcoln2,Mecp2,Ap3b1,Aim2,Pdpn,Pnpt1,Fchsd2,Rab11fip1,Ehd1,Arrdc4,Nfkbia,Dio2,Rab21,D1Ertd622e,Edn1,Stx6,Stau1,Dennd1b,Slc48a1,Tap2,Nod2,Zfp36,Dtx3l,Myc,Vps54,Svbp,Rnf19b,Rab3ip,Slc25a22,Rilpl1,Slc25a25,Slc29a3,Nos2,Arl4a,Rhbdf2,Aftph,Stat3,Myo1b,Nxf1,Sec24a,Nfkbie,Rrs1,Stx11,Hap1,Snx10,Tlr6,Lcp2,Nlrc4,Slco3a1,Rab19,Adar,Tlr2,Fam53c,Apba1,Tomm70a,Optn,Pou2f2,Chmp4b,Ranbp2,Notch1,Nlrp3,Plekhf2,Egr2,Stxbp1,Ric1,Syk,Snx2,Rffl,Magohb,Rtn2,Rab20,Serp1,Arl5c,Slc13a3,Ift57,Abcc1,Cdkn1a,Slc44a1,Pml,Dennd2a,Msr1,Stxbp3,Phip,Igf2bp2,Arl5b,Rabgef1,Rab10,Notch2,Calcrl,Slc7a5,Ift22,Slc25a12,Tbc1d1,Il1rn,Traf3ip2,Slc28a2,Cd74,G3bp2,Il6,Ap3m2,Kpna3,Cox18,Rab9,Trem1,Plek,Grk3,Rrbp1,Rtp4,Gja1,Itgav,Rab32,Tbc1d13,Parp11,Spire1,Slc7a8,Lyn,Slc15a3,Slc7a11,Slc7a2,Lrrc8c,Arf4,Hhex,Tap1,Isg15 |
| 1.441e-02 | -4.24 | GNF2_ITGB2 | MSigDB lists | GNF2_ITGB2 | 49 | 9 | 15632 | 1249 |
Fgr,Irf1,Casp1,Tnfrsf1b,Ptger4,Aoah,Hck,Hcls1,Myd88 |
| 1.441e-02 | -4.24 | PID_HES_HEY_PATHWAY | MSigDB lists | PID_HES_HEY_PATHWAY | 49 | 9 | 15632 | 1249 |
Hdac1,Notch1,Kdr,Jak2,Spen,Stat3,Rbbp8,Rcan1,Hif1a |
| 1.441e-02 | -4.24 | GO_CELLULAR_RESPONSE_TO_AMINO_ACID_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_AMINO_ACID_STIMULUS | 49 | 9 | 15632 | 1249 |
Zeb1,Pdgfc,Sh3bp4,Ass1,Ccl5,Fas,Cpeb4,Tnf,Socs1 |
| 1.441e-02 | -4.24 | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | MSigDB lists | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | 49 | 9 | 15632 | 1249 |
Psmd10,Psmb9,Hspa1a,Psmb10,Psme1,Psmb8,Psmb6,Psma6,Psme2 |
| 1.442e-02 | -4.24 | regulation of stem cell proliferation | biological process | GO:0072091 | 87 | 12 | 20694 | 1406 |
Ago3,Hmga2,Notch1,Taf4b,Cx3cr1,Hif1a,Vegfc,Cx3cl1,Pim1,Eif2ak2,Kitl,Cxcl1 |
| 1.443e-02 | -4.24 | FCH_dom | interpro domains | IPR001060 | 21 | 5 | 19984 | 1430 |
Pstpip2,Fnbp1l,Trip10,Fchsd2,Fcho2 |
| 1.443e-02 | -4.24 | PDEase_catalytic_dom | interpro domains | IPR002073 | 21 | 5 | 19984 | 1430 |
Pde4b,Pde5a,Pde1b,Pde3b,Pde7b |
| 1.443e-02 | -4.24 | Oxoglu/Fe-dep_dioxygenase | interpro domains | IPR005123 | 21 | 5 | 19984 | 1430 |
Egln3,P4ha2,P4ha1,Plod2,Plod3 |
| 1.443e-02 | -4.24 | PDEase_catalytic_dom_sf | interpro domains | IPR036971 | 21 | 5 | 19984 | 1430 |
Pde3b,Pde1b,Pde7b,Pde5a,Pde4b |
| 1.443e-02 | -4.24 | PDEase_CS | interpro domains | IPR023174 | 21 | 5 | 19984 | 1430 |
Pde3b,Pde1b,Pde7b,Pde5a,Pde4b |
| 1.445e-02 | -4.24 | GO_PROTEIN_HETERODIMERIZATION_ACTIVITY | MSigDB lists | GO_PROTEIN_HETERODIMERIZATION_ACTIVITY | 436 | 48 | 15632 | 1249 |
Hif1a,Pml,Notch1,Irak3,Pbx1,Bmp2,Tcf4,Eno1,Axl,Bcl2a1d,Il12b,Zhx2,Bcl2a1a,Irak2,Gca,Snx2,Inhba,Ext1,Pdgfb,Tlr1,Mpp7,Atf3,Ahr,Tap1,Gclc,Fos,Jun,Nr4a1,Bcl2a1b,Taf4b,Mid1,Bnip3,Gclm,Katna1,Mafg,Tlr2,Max,H3f3b,Dr1,Clcf1,Cav1,Itgal,Abtb2,Ikbkg,Nfkb1,Jdp2,Pdss1,Timeless |
| 1.445e-02 | -4.24 | WDR74 (WD repeat domain 74) | protein interactions | 54663 | 6 | 3 | 7778 | 753 |
Junb,Brwd3,Rrbp1 |
| 1.445e-02 | -4.24 | Rock1 (Rho-associated coiled-coil containing protein kinase 1) | protein interactions | 19877 | 6 | 3 | 7778 | 753 |
Rnd3,Casp3,Casp7 |
| 1.445e-02 | -4.24 | Cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit) | protein interactions | 12288 | 6 | 3 | 7778 | 753 |
Trim13,Cacnb3,Sqstm1 |
| 1.445e-02 | -4.24 | RAB5C (RAB5C, member RAS oncogene family) | protein interactions | 5878 | 6 | 3 | 7778 | 753 |
Ksr1,Flnb,Actb |
| 1.445e-02 | -4.24 | RPL3 (ribosomal protein L3) | protein interactions | 6122 | 6 | 3 | 7778 | 753 |
Rrbp1,Brwd3,Mdm2 |
| 1.445e-02 | -4.24 | Fas (Fas (TNF receptor superfamily member 6)) | protein interactions | 14102 | 6 | 3 | 7778 | 753 |
Daxx,Pml,Casp8 |
| 1.445e-02 | -4.24 | H1FX (H1 histone family member X) | protein interactions | 8971 | 6 | 3 | 7778 | 753 |
Rrbp1,Ksr1,Ktn1 |
| 1.445e-02 | -4.24 | Ub-specific processing proteases | REACTOME pathways | R-MMU-5689880 | 171 | 24 | 8608 | 757 |
Psmb6,Psme1,Psmb9,Hif1a,Usp42,Usp25,Ifih1,Psma6,Psme2,Ddx58,Traf2,Psmd10,Psmb8,Mdm2,Birc3,Ikbkg,Psmb10,Usp12,Nfkbia,Birc2,Psme2b,Usp18,Keap1,Adrb2 |
| 1.445e-02 | -4.24 | GO_CELL_ADHESION_MOLECULE_BINDING | MSigDB lists | GO_CELL_ADHESION_MOLECULE_BINDING | 158 | 21 | 15632 | 1249 |
Caml,Mmp14,S1pr2,Ezr,Src,Syk,Itgal,Ptpn2,Vcam1,Kdr,Thbs1,Nlgn2,Itga4,Itga5,Cd200,Tgfbi,Icam1,Cx3cl1,Lyn,Cdk5r1,Sell |
| 1.445e-02 | -4.24 | GSE38697_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP | MSigDB lists | GSE38697_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP | 158 | 21 | 15632 | 1249 |
Osgin2,Tab2,Ubash3b,Nsmaf,Nr4a3,Aim2,H3f3b,Slc37a3,Ppp2r2a,Whamm,Cd80,Ptch1,Eif4g2,Dpy19l1,Lztfl1,Cox17,Cd69,Rab10,Tlr1,Carhsp1,Egr2 |
| 1.446e-02 | -4.24 | GO_SPROUTING_ANGIOGENESIS | MSigDB lists | GO_SPROUTING_ANGIOGENESIS | 41 | 8 | 15632 | 1249 |
Jmjd6,Egr3,Nr4a1,Angpt1,Acvrl1,Notch1,Thbs1,Kdr |
| 1.446e-02 | -4.24 | GO_SCAFFOLD_PROTEIN_BINDING | MSigDB lists | GO_SCAFFOLD_PROTEIN_BINDING | 41 | 8 | 15632 | 1249 |
Trem1,Atp2b4,Mdm2,Lrp4,Gja1,Src,Casp8,Phf6 |
| 1.446e-02 | -4.24 | GO_CELLULAR_RESPONSE_TO_NUTRIENT | MSigDB lists | GO_CELLULAR_RESPONSE_TO_NUTRIENT | 41 | 8 | 15632 | 1249 |
Mdm2,Fzd1,Tnc,Il15,Pim1,Ccl5,Ccne1,Hmox1 |
| 1.446e-02 | -4.24 | KUNINGER_IGF1_VS_PDGFB_TARGETS_DN | MSigDB lists | KUNINGER_IGF1_VS_PDGFB_TARGETS_DN | 41 | 8 | 15632 | 1249 |
Dusp4,Rbpms,Errfi1,Slc37a3,Mmd,Tpx2,Timp1,Dusp6 |
| 1.449e-02 | -4.23 | Regulation of Hypoxia-inducible Factor (HIF) by oxygen | REACTOME pathways | R-MMU-1234174 | 68 | 12 | 8608 | 757 |
Egln3,Psme2b,Psme1,Psmd10,Psma6,Psme2,Psmb6,Hif1a,Psmb10,Psmb8,Psmb9,Cited2 |
| 1.449e-02 | -4.23 | Cellular response to hypoxia | REACTOME pathways | R-MMU-2262749 | 68 | 12 | 8608 | 757 |
Psme1,Psmb6,Hif1a,Cited2,Psmb9,Psmd10,Psme2b,Egln3,Psme2,Psma6,Psmb10,Psmb8 |
| 1.457e-02 | -4.23 | HANSON_HRAS_SIGNALING_VIA_NFKB | MSigDB lists | HANSON_HRAS_SIGNALING_VIA_NFKB | 19 | 5 | 15632 | 1249 |
Rnf19b,Clcf1,Klf3,Col18a1,Serpinb2 |
| 1.457e-02 | -4.23 | BIOCARTA_EPO_PATHWAY | MSigDB lists | BIOCARTA_EPO_PATHWAY | 19 | 5 | 15632 | 1249 |
Jak2,Stat5a,Fos,Jun,Map2k1 |
| 1.457e-02 | -4.23 | REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR | MSigDB lists | REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR | 19 | 5 | 15632 | 1249 |
Gnb4,Gng4,Ptgir,Gng11,Gng12 |
| 1.457e-02 | -4.23 | GO_CARBOHYDRATE_KINASE_ACTIVITY | MSigDB lists | GO_CARBOHYDRATE_KINASE_ACTIVITY | 19 | 5 | 15632 | 1249 |
Pfkl,Hk3,Hk2,Pfkfb3,Hk1 |
| 1.457e-02 | -4.23 | GO_AMINE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_AMINE_BIOSYNTHETIC_PROCESS | 19 | 5 | 15632 | 1249 |
Smox,Sat1,Srm,Odc1,Hdc |
| 1.457e-02 | -4.23 | LU_TUMOR_ENDOTHELIAL_MARKERS_UP | MSigDB lists | LU_TUMOR_ENDOTHELIAL_MARKERS_UP | 19 | 5 | 15632 | 1249 |
Mmp9,Lcp2,Hopx,Vcan,Adap2 |
| 1.457e-02 | -4.23 | GO_POSITIVE_REGULATION_OF_LIPID_STORAGE | MSigDB lists | GO_POSITIVE_REGULATION_OF_LIPID_STORAGE | 19 | 5 | 15632 | 1249 |
Ehd1,Nfkb1,Zc3h12a,C3,Msr1 |
| 1.457e-02 | -4.23 | ZHAN_MULTIPLE_MYELOMA_SPIKED | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_SPIKED | 19 | 5 | 15632 | 1249 |
Ifit3b,Ccnd1,Ifit3,Ednrb,Dusp2 |
| 1.457e-02 | -4.23 | GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | 19 | 5 | 15632 | 1249 |
Tnfsf4,Hlx,Tnfrsf14,Bcl6,Il4ra |
| 1.457e-02 | -4.23 | GO_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | 19 | 5 | 15632 | 1249 |
Src,Tnf,Mmp14,Thbs1,Acvrl1 |
| 1.457e-02 | -4.23 | organic acid transmembrane transport | biological process | GO:1903825 | 108 | 14 | 20694 | 1406 |
Slc16a1,Slc7a5,Slc7a11,Pdpn,Slc16a3,Slc7a8,Slc25a22,Abcc1,Myc,Slc7a2,Lrrc8c,Slc25a12,Slc13a3,Stra6l |
| 1.457e-02 | -4.23 | carboxylic acid transmembrane transport | biological process | GO:1905039 | 108 | 14 | 20694 | 1406 |
Slc25a22,Abcc1,Myc,Slc7a2,Slc25a12,Slc13a3,Lrrc8c,Stra6l,Slc16a1,Slc7a5,Slc7a11,Pdpn,Slc7a8,Slc16a3 |
| 1.462e-02 | -4.23 | ZHU_CMV_ALL_DN | MSigDB lists | ZHU_CMV_ALL_DN | 120 | 17 | 15632 | 1249 |
Tagln,Hivep2,Cnn2,Serpine1,Nr3c1,Ddit4,Cebpd,C1ra,Ccnd1,Vcan,Lox,Ralgds,Thbs1,Ldlr,Rbms1,Ahr,Igf1r |
| 1.462e-02 | -4.23 | Regnase_1/ZC3H12_C | interpro domains | IPR040757 | 3 | 2 | 19984 | 1430 |
Zc3h12a,Zc3h12c |
| 1.462e-02 | -4.23 | Cyclin_D | interpro domains | IPR015451 | 3 | 2 | 19984 | 1430 |
Ccnd1,Ccnd2 |
| 1.462e-02 | -4.23 | CC2-LZ_dom | interpro domains | IPR032419 | 3 | 2 | 19984 | 1430 |
Optn,Ikbkg |
| 1.462e-02 | -4.23 | OST-HTH/LOTUS_dom | interpro domains | IPR025605 | 3 | 2 | 19984 | 1430 |
Marf1,Tdrd7 |
| 1.462e-02 | -4.23 | GADD45 | interpro domains | IPR024824 | 3 | 2 | 19984 | 1430 |
Gadd45b,Gadd45g |
| 1.462e-02 | -4.23 | SP140 | interpro domains | IPR030411 | 3 | 2 | 19984 | 1430 |
Sp140,A530032D15Rik |
| 1.462e-02 | -4.23 | TBD | interpro domains | IPR024581 | 3 | 2 | 19984 | 1430 |
Azi2,Tank |
| 1.462e-02 | -4.23 | DUF3454_notch | interpro domains | IPR024600 | 3 | 2 | 19984 | 1430 |
Notch2,Notch1 |
| 1.462e-02 | -4.23 | JNK | interpro domains | IPR005643 | 3 | 2 | 19984 | 1430 |
Jun,Junb |
| 1.462e-02 | -4.23 | VEGFR-2_TMD | interpro domains | IPR041348 | 3 | 2 | 19984 | 1430 |
Kdr,Flt1 |
| 1.462e-02 | -4.23 | SPRE_EVH1 | interpro domains | IPR041937 | 3 | 2 | 19984 | 1430 |
Spred1,Spred3 |
| 1.462e-02 | -4.23 | VASP_tetra | interpro domains | IPR014885 | 3 | 2 | 19984 | 1430 |
Evl,Vasp |
| 1.462e-02 | -4.23 | Znf_NFX1 | interpro domains | IPR000967 | 3 | 2 | 19984 | 1430 |
Nfxl1,Znfx1 |
| 1.462e-02 | -4.23 | G_VLIG_dom | interpro domains | IPR030383 | 3 | 2 | 19984 | 1430 |
Gvin1,Gm4070 |
| 1.462e-02 | -4.23 | Procol_lys_dOase | interpro domains | IPR001006 | 3 | 2 | 19984 | 1430 |
Plod3,Plod2 |
| 1.462e-02 | -4.23 | VASP_sf | interpro domains | IPR038023 | 3 | 2 | 19984 | 1430 |
Vasp,Evl |
| 1.462e-02 | -4.23 | Pro_4_hyd_alph_N | interpro domains | IPR013547 | 3 | 2 | 19984 | 1430 |
P4ha2,P4ha1 |
| 1.462e-02 | -4.23 | CD164_MGC24 | interpro domains | IPR007947 | 3 | 2 | 19984 | 1430 |
Tmem123,Cd164 |
| 1.462e-02 | -4.23 | Selectin_CTLD | interpro domains | IPR033991 | 3 | 2 | 19984 | 1430 |
Sele,Sell |
| 1.462e-02 | -4.23 | Nuc_orph_rcpt | interpro domains | IPR003070 | 3 | 2 | 19984 | 1430 |
Nr4a3,Nr4a1 |
| 1.462e-02 | -4.23 | LOTUS-like | interpro domains | IPR041966 | 3 | 2 | 19984 | 1430 |
Tdrd7,Marf1 |
| 1.462e-02 | -4.23 | NEMO_ZF | interpro domains | IPR034735 | 3 | 2 | 19984 | 1430 |
Ikbkg,Optn |
| 1.462e-02 | -4.23 | KBD | interpro domains | IPR023337 | 3 | 2 | 19984 | 1430 |
Spred3,Spred1 |
| 1.462e-02 | -4.23 | POLO_box_2 | interpro domains | IPR033695 | 3 | 2 | 19984 | 1430 |
Plk2,Plk3 |
| 1.462e-02 | -4.23 | Selectin_superfamily | interpro domains | IPR002396 | 3 | 2 | 19984 | 1430 |
Sell,Sele |
| 1.462e-02 | -4.23 | Leuzip_Jun | interpro domains | IPR002112 | 3 | 2 | 19984 | 1430 |
Jun,Junb |
| 1.462e-02 | -4.23 | CARD_dom | interpro domains | IPR031964 | 3 | 2 | 19984 | 1430 |
Ifih1,Ddx58 |
| 1.462e-02 | -4.23 | Neurexin-like | interpro domains | IPR003585 | 14 | 4 | 19984 | 1430 |
Sdc1,Sdc4,Sdc2,Gypc |
| 1.462e-02 | -4.23 | regulation of cardiac muscle tissue growth | biological process | GO:0055021 | 77 | 11 | 20694 | 1406 |
Trip10,Jarid2,Pim1,Sav1,Notch1,Tomm70a,Cited2,Nr3c1,Edn1,Gja1,Sirt1 |
| 1.470e-02 | -4.22 | AR_01 | MSigDB lists | AR_01 | 139 | 19 | 15632 | 1249 |
Pim2,Zfp513,Ell2,Smox,Prdm1,Calcrl,Rbms2,Jak2,Cdkn1a,Etv5,Fam162a,Abtb2,Slc7a8,Bcl6,Psme2,Rab10,Dtnb,Psma6,Zfp800 |
| 1.470e-02 | -4.22 | regulation of nervous system process | biological process | GO:0031644 | 174 | 20 | 20694 | 1406 |
Acpp,Ctsc,Il10,Cst7,Src,Tnfrsf1b,Gpr35,Fcgr4,Ednrb,Cacnb3,Adrb2,Slc9a1,Il1a,Tnf,Homer1,Ptafr,Edn1,S1pr2,Nlgn2,Il6 |
| 1.471e-02 | -4.22 | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_UP | 168 | 22 | 15632 | 1249 |
Ifit3,Fosb,Junb,Ccl5,Xaf1,Oas2,H2-Aa,Acvr1b,Arid5b,Ifit3b,St3gal1,Cmpk2,Tnip1,Znfx1,Cd40,Usp18,Ifit1,Stau1,Hck,Nod1,Traf5,Ciita |
| 1.471e-02 | -4.22 | HOXA9_DN.V1_DN | MSigDB lists | HOXA9_DN.V1_DN | 168 | 22 | 15632 | 1249 |
Spry2,Fcgr2b,Phlpp1,Taf4b,Cst7,Psip1,Apobec3,Acpp,Bfar,Sav1,Itga4,Hhex,Mcm10,Egr1,Plagl1,Myo1b,Slc7a2,Notch2,Rgs1,Hmgcs1,Aida,Trib3 |
| 1.471e-02 | -4.22 | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN | 168 | 22 | 15632 | 1249 |
Tap1,Rnf34,Bfar,Cflar,Prdx1,Mthfd2,Mcm6,Trib1,Ppa1,Fas,Casp3,Tmem184b,Ptch1,Rbbp8,Cav1,Cd86,Higd1a,Csrp1,Bcl2l11,Ccne1,Txn1,Eno2 |
| 1.474e-02 | -4.22 | positive regulation of pathway-restricted SMAD protein phosphorylation | biological process | GO:0010862 | 48 | 8 | 20694 | 1406 |
Inhba,Lgals9,Acvr1,Bmp2,Gdf15,Acvr1b,Rbpms,Acvrl1 |
| 1.474e-02 | -4.22 | negative regulation of lymphocyte apoptotic process | biological process | GO:0070229 | 48 | 8 | 20694 | 1406 |
Bcl2a1a,Hif1a,Arg2,Cd74,Irs2,Serpinb9,Ccl5,Tnfsf4 |
| 1.474e-02 | -4.22 | ADP metabolic process | biological process | GO:0046031 | 48 | 8 | 20694 | 1406 |
Hk3,Hk1,Ampd3,Hk2,Pfkl,Pgk1,Tpi1,Eno2 |
| 1.474e-02 | -4.22 | Keap1-Nrf2 | WikiPathways | WP1245 | 14 | 5 | 4813 | 540 |
Gclm,Keap1,Hmox1,Nqo1,Gclc |
| 1.475e-02 | -4.22 | GO_RESPONSE_TO_INTERLEUKIN_6 | MSigDB lists | GO_RESPONSE_TO_INTERLEUKIN_6 | 26 | 6 | 15632 | 1249 |
St3gal6,Pid1,Ccl12,Nfkb1,Il6,Stat3 |
| 1.475e-02 | -4.22 | GO_PROSTANOID_METABOLIC_PROCESS | MSigDB lists | GO_PROSTANOID_METABOLIC_PROCESS | 26 | 6 | 15632 | 1249 |
Ptgs2,Cd74,Sphk1,Ptges,Edn1,Pdpn |
| 1.475e-02 | -4.22 | BIOCARTA_RACCYCD_PATHWAY | MSigDB lists | BIOCARTA_RACCYCD_PATHWAY | 26 | 6 | 15632 | 1249 |
Ccne1,Nfkb1,Ikbkg,Nfkbia,Cdkn1a,Ccnd1 |
| 1.475e-02 | -4.22 | GO_REGULATION_OF_CELLULAR_SENESCENCE | MSigDB lists | GO_REGULATION_OF_CELLULAR_SENESCENCE | 26 | 6 | 15632 | 1249 |
Pnpt1,Nek6,Eef1e1,Bcl6,Hmga1,Sirt1 |
| 1.475e-02 | -4.22 | BIOCARTA_NKCELLS_PATHWAY | MSigDB lists | BIOCARTA_NKCELLS_PATHWAY | 26 | 6 | 15632 | 1249 |
Il18,Map2k1,H2-Q6,Syk,H2-Q4,H2-Q7 |
| 1.475e-02 | -4.22 | SHIN_B_CELL_LYMPHOMA_CLUSTER_7 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_7 | 26 | 6 | 15632 | 1249 |
Zfp36,Pml,Max,Ptch1,Bcl6,Igf1r |
| 1.475e-02 | -4.22 | GO_OSTEOCLAST_DIFFERENTIATION | MSigDB lists | GO_OSTEOCLAST_DIFFERENTIATION | 26 | 6 | 15632 | 1249 |
Csf1,Junb,Tnf,Snx10,Src,Fam20c |
| 1.475e-02 | -4.22 | IKEDA_MIR30_TARGETS_DN | MSigDB lists | IKEDA_MIR30_TARGETS_DN | 26 | 6 | 15632 | 1249 |
Rnf139,Chd9,Gja1,Bcl2l11,Tmeff1,Mmd |
| 1.475e-02 | -4.22 | PID_IL3_PATHWAY | MSigDB lists | PID_IL3_PATHWAY | 26 | 6 | 15632 | 1249 |
Osm,Pim1,Hdac1,Cish,Jak2,Stat5a |
| 1.475e-02 | -4.22 | GO_RIBONUCLEOTIDE_CATABOLIC_PROCESS | MSigDB lists | GO_RIBONUCLEOTIDE_CATABOLIC_PROCESS | 26 | 6 | 15632 | 1249 |
Pde3b,Pde1b,Ampd3,Pde4b,Pde5a,Pde7b |
| 1.475e-02 | -4.22 | PID_IL8_CXCR1_PATHWAY | MSigDB lists | PID_IL8_CXCR1_PATHWAY | 26 | 6 | 15632 | 1249 |
Gna15,Fgr,Lyn,Pik3r6,Hck,Prkce |
| 1.475e-02 | -4.22 | PID_INTEGRIN_CS_PATHWAY | MSigDB lists | PID_INTEGRIN_CS_PATHWAY | 26 | 6 | 15632 | 1249 |
Itga9,Itgal,Itga4,Itga5,Itgav,Itgb8 |
| 1.475e-02 | -4.22 | MODULE_281 | MSigDB lists | MODULE_281 | 26 | 6 | 15632 | 1249 |
Dusp6,Dusp5,Fubp1,Arf4,Serpinb2,Dusp14 |
| 1.475e-02 | -4.22 | ROZANOV_MMP14_TARGETS_DN | MSigDB lists | ROZANOV_MMP14_TARGETS_DN | 26 | 6 | 15632 | 1249 |
Rtn1,Ehd1,Flrt2,Nmral1,Sdc4,Triobp |
| 1.475e-02 | -4.22 | TSENG_ADIPOGENIC_POTENTIAL_UP | MSigDB lists | TSENG_ADIPOGENIC_POTENTIAL_UP | 26 | 6 | 15632 | 1249 |
Ch25h,Dbnl,Trib3,Adora2b,Rhou,Mthfd2 |
| 1.481e-02 | -4.21 | WESTON_VEGFA_TARGETS_3HR | MSigDB lists | WESTON_VEGFA_TARGETS_3HR | 66 | 11 | 15632 | 1249 |
Kdr,Hcls1,Pnp2,Tnfsf10,Sat1,Vcam1,Cd34,Ccl12,Pde4b,Nr4a1,Pim1 |
| 1.481e-02 | -4.21 | MCCLUNG_COCAIN_REWARD_4WK | MSigDB lists | MCCLUNG_COCAIN_REWARD_4WK | 66 | 11 | 15632 | 1249 |
Caml,Sirt1,Dusp1,Nr4a1,P4ha1,Dusp6,Swap70,Znfx1,Fos,Serpinb2,Pbx1 |
| 1.481e-02 | -4.21 | JAIN_NFKB_SIGNALING | MSigDB lists | JAIN_NFKB_SIGNALING | 66 | 11 | 15632 | 1249 |
Tap2,Ascc3,Hspa1a,Flt1,Hk2,Jak2,Ctsc,Bnip3,Plau,Myc,Smg7 |
| 1.481e-02 | -4.21 | PID_RB_1PATHWAY | MSigDB lists | PID_RB_1PATHWAY | 66 | 11 | 15632 | 1249 |
Met,Cebpd,Mdm2,Hdac1,Ccnd1,Sirt1,Ccne1,Brd2,Jun,Cdkn1a,Ccnd2 |
| 1.481e-02 | -4.21 | GO_CELL_AGING | MSigDB lists | GO_CELL_AGING | 66 | 11 | 15632 | 1249 |
Icam1,Cav1,Map2k1,Hmga1,Serpine1,Atm,Morc3,Smc5,Pml,Sirt1,Cdkn1a |
| 1.481e-02 | -4.21 | GO_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | 66 | 11 | 15632 | 1249 |
Atp2b4,Psme1,Psmb6,Odc1,Psmb10,Psme2,Nqo1,Psma6,Psmb8,Psmd10,Psmb9 |
| 1.481e-02 | -4.21 | HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_UP | 66 | 11 | 15632 | 1249 |
Ehd1,Psat1,Cd40,H2-Aa,H2-Ab1,Cd74,Ccnd2,Icam1,Cd83,Sdc4,Rbms2 |
| 1.481e-02 | -4.21 | LANDIS_BREAST_CANCER_PROGRESSION_DN | MSigDB lists | LANDIS_BREAST_CANCER_PROGRESSION_DN | 66 | 11 | 15632 | 1249 |
Ppp2r5a,Htra1,Alas1,Gja1,Plac8,Cd34,Nr1h3,St3gal6,Tgfbi,Phyh,Col18a1 |
| 1.481e-02 | -4.21 | Nfe2l2 (nuclear factor, erythroid derived 2, like 2) | protein interactions | 18024 | 16 | 5 | 7778 | 753 |
Cdkn1a,Mafg,Keap1,Mafk,Fos |
| 1.481e-02 | -4.21 | Hist4h4 (histone cluster 4, H4) | protein interactions | 320332 | 16 | 5 | 7778 | 753 |
Hdac1,Daxx,Egr1,Hspa1b,Myc |
| 1.481e-02 | -4.21 | Stat1 (signal transducer and activator of transcription 1) | protein interactions | 20846 | 16 | 5 | 7778 | 753 |
Ptpn2,Stat3,Atf3,Rnf19b,Stat1 |
| 1.481e-02 | -4.21 | CC2-LZ | pfam domains | PF16516 | 3 | 2 | 18711 | 1348 |
Optn,Ikbkg |
| 1.481e-02 | -4.21 | VASP_tetra | pfam domains | PF08776 | 3 | 2 | 18711 | 1348 |
Evl,Vasp |
| 1.481e-02 | -4.21 | DUF3454 | pfam domains | PF11936 | 3 | 2 | 18711 | 1348 |
Notch2,Notch1 |
| 1.481e-02 | -4.21 | Regnase_1_C | pfam domains | PF18561 | 3 | 2 | 18711 | 1348 |
Zc3h12c,Zc3h12a |
| 1.481e-02 | -4.21 | TBD | pfam domains | PF12845 | 3 | 2 | 18711 | 1348 |
Azi2,Tank |
| 1.481e-02 | -4.21 | CARD_2 | pfam domains | PF16739 | 3 | 2 | 18711 | 1348 |
Ifih1,Ddx58 |
| 1.481e-02 | -4.21 | VEGFR-2_TMD | pfam domains | PF17988 | 3 | 2 | 18711 | 1348 |
Flt1,Kdr |
| 1.481e-02 | -4.21 | P4Ha_N | pfam domains | PF08336 | 3 | 2 | 18711 | 1348 |
P4ha2,P4ha1 |
| 1.481e-02 | -4.21 | Jun | pfam domains | PF03957 | 3 | 2 | 18711 | 1348 |
Junb,Jun |
| 1.481e-02 | -4.21 | PID_2 | pfam domains | PF14719 | 3 | 2 | 18711 | 1348 |
Pid1,Fam43a |
| 1.481e-02 | -4.21 | MGC-24 | pfam domains | PF05283 | 3 | 2 | 18711 | 1348 |
Tmem123,Cd164 |
| 1.481e-02 | -4.21 | OST-HTH | pfam domains | PF12872 | 3 | 2 | 18711 | 1348 |
Marf1,Tdrd7 |
| 1.483e-02 | -4.21 | JmjC | pfam domains | PF02373 | 21 | 5 | 18711 | 1348 |
Kdm5b,Kdm6b,Kdm4a,Jmjd6,Jarid2 |
| 1.483e-02 | -4.21 | TNFR_c6 | pfam domains | PF00020 | 21 | 5 | 18711 | 1348 |
Fas,Tnfrsf14,Tnfrsf8,Cd40,Tnfrsf1b |
| 1.483e-02 | -4.21 | PDEase_I | pfam domains | PF00233 | 21 | 5 | 18711 | 1348 |
Pde3b,Pde1b,Pde7b,Pde4b,Pde5a |
| 1.484e-02 | -4.21 | embryonic organ development | biological process | GO:0048568 | 487 | 46 | 20694 | 1406 |
Spry2,Notch2,Vcam1,Tshz1,Edn1,Triobp,Clic5,Zeb1,Mmp14,Junb,Fzd5,Pdgfrb,Itga4,Sec24b,Myc,Kitl,Socs3,Kdr,Tulp3,Phactr4,Cited2,Acvr1,Eya4,Il10,Prdm1,Ift57,Nr4a3,Pbx1,Ahr,Chst11,Spint2,Gja1,Ptch1,Itgav,Hhex,Notch1,Gfi1,Mthfd1l,Pdgfc,Ttc39c,Abr,Hlx,Hif1a,Pdgfb,Lif,Map2k1 |
| 1.489e-02 | -4.21 | positive regulation of G1/S transition of mitotic cell cycle | biological process | GO:1900087 | 39 | 7 | 20694 | 1406 |
Mdm2,Ankrd17,Ube2e2,Ccnd2,Ccne1,Rgcc,Ccnd1 |
| 1.489e-02 | -4.21 | myeloid leukocyte mediated immunity | biological process | GO:0002444 | 39 | 7 | 20694 | 1406 |
Rasgrp1,Stx11,Trem1,Nr4a3,Fcgr1,Milr1,Lyn |
| 1.489e-02 | -4.21 | GSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | MSigDB lists | GSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | 178 | 23 | 15632 | 1249 |
Tmem229b,Kmo,Aida,Lyn,Azi2,Cflar,Crlf3,Zcchc2,Rsbn1,Nfkb2,Hvcn1,Clcn5,Acp2,Samhd1,Nfkb1,Abcc5,Casp8,Rhof,Irf4,Parp14,Ctsc,Slc2a6,Uba7 |
| 1.489e-02 | -4.21 | GSE14308_TH2_VS_TH17_DN | MSigDB lists | GSE14308_TH2_VS_TH17_DN | 178 | 23 | 15632 | 1249 |
Sco1,Jarid2,Mthfd1l,Rnf19a,Nfkbie,Pla2g7,Hdac1,Il18rap,Ext1,Cysltr2,Stxbp3,Nxf1,Tlr2,Arid5b,Dtx2,Tpi1,Pml,Snn,Myo10,Rbms2,Sav1,Ppp2r1b,1600014C10Rik |
| 1.489e-02 | -4.21 | GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 178 | 23 | 15632 | 1249 |
Gypc,Irf4,Aebp2,Prdx5,Psme1,Psmb10,Ifih1,Isg15,Prdx1,Zbp1,Eif4g2,Card6,Rnaset2a,Ksr1,Oas2,Pim2,C3,Phyh,Actb,Acsl5,Hcls1,Rnaset2b,Esd |
| 1.489e-02 | -4.21 | GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_UP | MSigDB lists | GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_UP | 178 | 23 | 15632 | 1249 |
Gclm,Procr,Psme2,Bst1,Cox17,Hk2,P4ha2,Apobec3,Hk1,Csrp1,Dusp6,Fzd5,Myo1b,Gpsm2,Etv5,Trem1,Ifi35,Magohb,Slc31a1,Psmb6,Parp11,Isg15,Tpx2 |
| 1.489e-02 | -4.21 | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_6H_DN | MSigDB lists | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_6H_DN | 178 | 23 | 15632 | 1249 |
Rhof,Stat5a,Nlrc5,Il18bp,B3gnt5,Parp14,Carhsp1,Ifi44,Cx3cl1,Tap1,Rbl1,Tnks1bp1,Herc3,Rnaset2a,Ahrr,Myadm,Map4k4,Acvr1b,Ttc39b,Ptprj,Stat1,Rnaset2b,Gtpbp2 |
| 1.489e-02 | -4.21 | GSE17721_4_VS_24H_CPG_BMDC_DN | MSigDB lists | GSE17721_4_VS_24H_CPG_BMDC_DN | 178 | 23 | 15632 | 1249 |
Eif4g2,Il10,Procr,Antxr1,Pdlim7,Stat4,Mmp9,Grina,Acsl5,Nfil3,Dusp1,Gramd1a,Spn,Abcc5,Fos,Cyfip1,Jun,Egr2,Ift57,Ankrd24,Tulp3,Slc39a13,Sla |
| 1.489e-02 | -4.21 | GSE6674_ANTI_IGM_VS_CPG_STIM_BCELL_UP | MSigDB lists | GSE6674_ANTI_IGM_VS_CPG_STIM_BCELL_UP | 178 | 23 | 15632 | 1249 |
Sla,Evl,Fas,Spata13,Cyth3,Sertad3,Lztfl1,Ccng2,P4ha2,Usp53,Bcl2l11,Otud1,Bcl6,Tnip1,Ikbke,Mtmr14,Ptgir,Dnajb4,Bcl9,Adora2a,4930523C07Rik,Ttc9c,Jdp2 |
| 1.489e-02 | -4.21 | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN | 178 | 23 | 15632 | 1249 |
Ass1,Gch1,Fos,Klf2,Slc44a1,Arl5b,Slpi,Tnfsf8,Spen,Pde5a,Rin2,Filip1l,Slc30a4,Ppm1l,Sell,Znrf3,Mob3b,Gnb4,Plcl2,Atp11b,Snn,Rab3ip,Klf7 |
| 1.489e-02 | -4.21 | GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_DN | MSigDB lists | GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_DN | 178 | 23 | 15632 | 1249 |
Rbms1,Orai2,Ust,Dcbld2,Mob3c,Frmd6,Ptgir,Trib3,Ep400,Rasgrp1,Dgka,Clic5,Cnp,Nod1,Mapkbp1,Rab3ip,Trim13,Il4ra,Ppm1l,Irgm2,Cish,Treml2,Ets2 |
| 1.489e-02 | -4.21 | GSE3982_DC_VS_TH1_UP | MSigDB lists | GSE3982_DC_VS_TH1_UP | 178 | 23 | 15632 | 1249 |
Pdgfc,Pilra,Plau,Gpc1,Fgr,Cnot4,Nfkbie,Pde5a,Fcgr2b,Slc15a3,Igsf6,Bcl6,Flt1,Clcn7,Tgfbi,Adora2b,Il18,Tlr2,Dram1,Ptk2,Parp12,Spint2,Adap2 |
| 1.489e-02 | -4.21 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D | 238 | 29 | 15632 | 1249 |
Ptk2,Kcna3,Bcl2a1a,Cflar,Osbpl3,Snapc1,Vegfc,Hk1,Slc12a9,Spen,Tmem176a,Tpi1,Aldh1b1,Slc30a1,Pgm1,Calcrl,Sgcb,Extl2,Ccl12,Plod3,Bcl2a1b,Gadd45b,Gsdmd,Trip10,Dennd1b,Pdpn,Fcgr2b,Phgdh,Bcl2a1d |
| 1.492e-02 | -4.21 | phospholipid binding | molecular function | GO:0005543 | 417 | 41 | 20217 | 1400 |
Thbs1,Tulp3,Lpar1,Apba1,Cyth3,Cd300lf,Plekhn1,Plekha4,Axl,Ptafr,Snx2,Aida,Plekha2,Jag1,Gsdmd,Dennd1b,Plekha5,Rnf34,Rasgrp1,Rubcnl,Sgk3,Zcchc2,Psd,Kcnj2,Pla2g4a,F10,Mitd1,Pla2g7,Wdfy1,Dgka,Adap2,Arhgap26,Snx10,Myo1b,Itpr1,Plek,Plekhf2,Fchsd2,Cgas,Rapgef2,Fcho2 |
| 1.493e-02 | -4.20 | Cebpb (CCAAT/enhancer binding protein beta) | protein interactions | 24253 | 48 | 10 | 7778 | 753 |
Ranbp2,Azi2,Ppp2r1b,Rars,Golga3,Filip1l,Rai14,Myo10,Uaca,P4ha1 |
| 1.494e-02 | -4.20 | HSP70_3 | prosite domains | PS01036 | 13 | 4 | 13278 | 1037 |
Hsph1,Hspa1a,Hspa1b,Hspa2 |
| 1.496e-02 | -4.20 | cellular response to external stimulus | biological process | GO:0071496 | 279 | 29 | 20694 | 1406 |
Cnn2,Wdr59,Piezo1,Eif2ak2,P2ry12,Jun,Sesn3,Fos,Higd1a,Ptger4,Cdkn1a,Atf3,Adora2b,Nmral1,Asns,Ldha,Cpeb4,Pim1,Fas,Cav1,Slc39a4,Vcam1,Axl,Gsdmd,Zc3h12a,Mmp9,Sirt1,Slc2a1,Itga4 |
| 1.500e-02 | -4.20 | GO_ORGANOPHOSPHATE_CATABOLIC_PROCESS | MSigDB lists | GO_ORGANOPHOSPHATE_CATABOLIC_PROCESS | 111 | 16 | 15632 | 1249 |
Pgm1,Upp1,Gda,Samhd1,Lipg,Pde3b,Inpp1,Cnp,Pde4b,Smpdl3b,Pde5a,Pde7b,Pla2g4a,Pnp2,Pde1b,Ampd3 |
| 1.501e-02 | -4.20 | GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_DN | MSigDB lists | GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_DN | 188 | 24 | 15632 | 1249 |
Nr1h3,St3gal6,Abr,Marcksl1,Hhex,Dusp14,Myo10,Olr1,Pde3b,Hmga1,Slc16a3,Rin2,Rab9,Il18,Acp2,Tnip1,Gna15,Rrs1,Serpine1,Atm,Psd4,Eef1e1,Ampd3,Phlda1 |
| 1.501e-02 | -4.20 | GTATTAT_MIR3693P | MSigDB lists | GTATTAT_MIR3693P | 188 | 24 | 15632 | 1249 |
Larp1,Gpr85,Clic4,Rsbn1,Dr1,Vegfc,Pde4b,Arid4a,Ptch1,Med13,Rab10,Zeb1,Pde7b,Mmd,Sirt1,Ube2e2,St3gal3,Pikfyve,Zfp281,Etv5,Spred1,Flrt3,Hsph1,Peli1 |
| 1.501e-02 | -4.20 | GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_DN | 188 | 24 | 15632 | 1249 |
Slc16a1,Chmp4b,Nek6,Prdm1,Fas,Usp18,Icam1,Plac8,Klf6,Ezr,Gadd45b,Ets2,Il1rn,Wdr43,Ldha,Gng4,Azi2,Rcn1,Ube2l6,Caml,Ccl5,Hsd17b12,Lcn2,Gna15 |
| 1.501e-02 | -4.20 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | MSigDB lists | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | 188 | 24 | 15632 | 1249 |
Psmd10,Psmb9,Srm,Ass1,Psma6,Nqo1,Phgdh,Sat1,Gclm,Kmo,Arg2,Psmb10,Psme1,Gclc,Asns,Hdc,Psmb8,Psat1,Inhba,Psme2,Odc1,Smox,Psmb6,Dio2 |
| 1.502e-02 | -4.20 | central nervous system development | biological process | GO:0007417 | 833 | 73 | 20694 | 1406 |
Axl,Akt3,Notch1,Hhex,Hmga2,Il1b,Tal2,Btg2,Slc7a11,Inhba,Tlr2,Cdk5r1,Nr4a3,Crkl,Sphk1,Lmo4,Ptch1,Fpr2,Adgrl2,Hap1,Map2k1,Bmp2,Ptprj,Lhx2,Rapgef2,Nrp2,B3gnt5,Src,Stat3,Abr,Syne2,Phgdh,Lif,Atm,Scn1b,Vcan,Hif1a,Pou3f1,C3,Ptk2,Rac3,Zeb1,Kdm6b,Fabp7,Sec24b,Rpgrip1l,Slc4a7,Irs2,Lrp8,Igf1r,D16Ertd472e,Socs7,Sema4c,Stxbp3,Ext1,Tsku,Cnp,Cx3cr1,S100a8,Fcgr2b,Intu,Ddit4,Apaf1,Hdac1,Met,Ikzf1,P2ry12,Adora2a,Tulp3,Cited2,Plpp3,Mecp2,Egr2 |
| 1.508e-02 | -4.19 | apical part of cell | cellular component | GO:0045177 | 413 | 40 | 20747 | 1409 |
Stxbp3,Il18,Vcam1,Cav1,Notch1,Cacnb3,Slc9a1,P2ry2,Rapgef2,Slc2a1,Slco3a1,Jag1,Acvr1,Slc39a4,Homer1,Cd34,Pdpn,Pdgfrb,Clic4,Svbp,Ldlr,Slc4a7,Cd55,Fas,Myo1b,Tlr9,Cldnd1,Plat,Adrb2,Acpp,Hspa1a,Cacna1d,Clcn5,Gja1,Mtdh,Ptk2,Gpsm2,Ezr,Snx10,Abcb1a |
| 1.509e-02 | -4.19 | AAAGGGA_MIR204_MIR211 | MSigDB lists | AAAGGGA_MIR204_MIR211 | 208 | 26 | 15632 | 1249 |
Rap2c,Kitl,Slc37a3,Crkl,Ell2,Tmod3,Kcna3,St7,Rab10,Bcl9,Rictor,Sirt1,Eef1e1,Dcun1d3,Pid1,Spred1,Ncoa7,Angpt1,Myo10,Xrn1,Nr3c1,Cpd,Ezr,Spryd7,Itpr1,Mrpl52 |
| 1.510e-02 | -4.19 | - | gene3d domains | 2.60.34.10 | 12 | 4 | 8819 | 755 |
Hsph1,Hspa1a,Hspa2,Hspa1b |
| 1.512e-02 | -4.19 | GSE6566_STRONG_VS_WEAK_DC_STIMULATED_CD4_TCELL_UP | MSigDB lists | GSE6566_STRONG_VS_WEAK_DC_STIMULATED_CD4_TCELL_UP | 149 | 20 | 15632 | 1249 |
Nmi,Isg20,Micall2,Hk2,Oas2,Cxcl2,Pla2g7,Nr4a1,Oas3,Kitl,Ldlr,Jak2,Zcchc2,Batf,Fam102b,Nfil3,Tap1,Mefv,Arrdc4,Usp18 |
| 1.512e-02 | -4.19 | MIKKELSEN_IPS_LCP_WITH_H3K4ME3 | MSigDB lists | MIKKELSEN_IPS_LCP_WITH_H3K4ME3 | 149 | 20 | 15632 | 1249 |
Tnks1bp1,Glrx,Mark2,Hvcn1,Ccdc88b,Tnip1,Sema4a,Tapbpl,Ifi35,Ebi3,Xaf1,Wars,Slc39a4,Gpr35,Trim21,C1rl,Hdc,Oas3,Pdgfrb,Snx10 |
| 1.513e-02 | -4.19 | Ank | pfam domains | PF00023 | 37 | 7 | 18711 | 1348 |
Ankib1,Nfkb1,Nfkbia,Ankrd17,Nfkbid,Ankrd24,Psmd10 |
| 1.519e-02 | -4.19 | response to unfolded protein | biological process | GO:0006986 | 98 | 13 | 20694 | 1406 |
Daxx,Eif2ak2,Ccnd1,Hspa2,Ero1l,Hspa1a,Atf3,Optn,Thbs1,Hsph1,Serp1,Hspa1b,Ppp1r15a |
| 1.520e-02 | -4.19 | GO_GLAND_DEVELOPMENT | MSigDB lists | GO_GLAND_DEVELOPMENT | 384 | 43 | 15632 | 1249 |
Crkl,Arid5b,Ak4,Hk2,Jarid2,Map2k1,Asns,Pbx1,Bmp2,Ripk3,Notch1,Pml,Hhex,Hlx,Hif1a,Cp,Tnc,Ccnd1,Kdm5b,Stat5a,Tnf,Src,Psmb9,Jak2,Rpgrip1l,Hmgcs1,Adrb2,Csf1,Ccne1,Lmo4,Ptch1,Cav1,Sema3c,Tspo,Fas,Irs2,Il6,Ass1,Bcl2l11,Ezr,Jun,Cited2,Tet2 |
| 1.524e-02 | -4.18 | actin cytoskeleton | cellular component | GO:0015629 | 488 | 46 | 20747 | 1409 |
Tpm4,Clic5,Pstpip2,Pdlim7,Kif9,Cnn3,Ddx58,Flt1,Lad1,Triobp,Gbp2,Myo10,Fscn1,Tmod3,Actb,Rhoq,Cdc42ep4,Hck,Carmil1,Dbnl,Gng12,Cnn2,Hcls1,Myo1b,Rac3,Marcks,Palld,Mark2,Keap1,Ptk2,Dst,Src,Ncoa5,Fgr,Dennd2a,Flnb,Ezr,Zyx,Rnd1,Daam1,Micall2,Kat2b,Vcam1,Myadm,Csrp1,Slc2a1 |
| 1.526e-02 | -4.18 | KEGG_INSULIN_SIGNALING_PATHWAY | MSigDB lists | KEGG_INSULIN_SIGNALING_PATHWAY | 130 | 18 | 15632 | 1249 |
Irs2,Pik3cd,Socs1,Crkl,Socs3,Hk3,Prkar2b,Prkx,Gys1,Pde3b,Map2k1,Trip10,Lipe,Hk1,Pik3r5,Hk2,Akt3,Rhoq |
| 1.529e-02 | -4.18 | GO_RUFFLE_MEMBRANE | MSigDB lists | GO_RUFFLE_MEMBRANE | 75 | 12 | 15632 | 1249 |
Ezr,Src,Ptprj,Plek,Itga5,Itgav,Spata13,Ddx58,Fgr,Arf4,Spry2,Pdpn |
| 1.529e-02 | -4.18 | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | MSigDB lists | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 75 | 12 | 15632 | 1249 |
Malt1,Casp7,Uchl1,Cflar,Gca,Casp8,Casp4,Casp1,Usp12,Casp2,Casp3,Ctsc |
| 1.530e-02 | -4.18 | KEGG_PROSTATE_CANCER | MSigDB lists | KEGG_PROSTATE_CANCER | 102 | 15 | 15632 | 1249 |
Pdgfc,Igf1r,Cdkn1a,Pik3cd,Ccnd1,Mdm2,Pdgfb,Akt3,Pdgfrb,Map2k1,Nfkbia,Ikbkg,Nfkb1,Pik3r5,Ccne1 |
| 1.538e-02 | -4.17 | exoribonuclease activity, producing 5'-phosphomonoesters | molecular function | GO:0016896 | 30 | 6 | 20217 | 1400 |
Noct,Isg20,Pnpt1,Usb1,Xrn1,Dcp2 |
| 1.540e-02 | -4.17 | Nicotinate metabolism | REACTOME pathways | R-MMU-196807 | 24 | 6 | 8608 | 757 |
Ptgs2,Parp9,Parp10,Nampt,Cd38,Bst1 |
| 1.545e-02 | -4.17 | exogenous protein binding | molecular function | GO:0140272 | 22 | 5 | 20217 | 1400 |
Cd55,Tnfrsf14,Cd300lf,Pvr,Clec5a |
| 1.545e-02 | -4.17 | virus receptor activity | molecular function | GO:0001618 | 22 | 5 | 20217 | 1400 |
Clec5a,Pvr,Cd300lf,Cd55,Tnfrsf14 |
| 1.545e-02 | -4.17 | transforming growth factor beta binding | molecular function | GO:0050431 | 22 | 5 | 20217 | 1400 |
Acvrl1,Vasn,Acvr1,Thbs1,Agrn |
| 1.548e-02 | -4.17 | WEI_MYCN_TARGETS_WITH_E_BOX | MSigDB lists | WEI_MYCN_TARGETS_WITH_E_BOX | 700 | 72 | 15632 | 1249 |
Slc16a1,Pnpt1,Me1,Dusp14,Lrp8,Ccnd2,Pgm1,Sdc1,Gclm,Ggct,Taf4b,Vcan,Nr4a1,Srm,Dr1,Idi1,Fam162a,Stard7,Wdr43,Mtdh,Nox1,Endod1,Odc1,Acvr1b,Trib1,Gpd2,Lyn,Slc9a1,Srxn1,Trip13,Nfkbib,Slc39a14,Hat1,Eef1e1,Tor3a,Ccne1,Ahrr,Sco1,Gem,Casp8,Ahsa1,Cutc,Mcmbp,Mcm10,Asap3,Sphk1,Pnp2,Mlkl,Cers6,Hsph1,Homer1,Eno1,Hspa1a,Kitl,Rcl1,Dcbld2,Stip1,Zhx2,Pgk1,Trafd1,Abcc4,Naa25,Dusp5,Ripk2,Spata5l1,Sap30,Hk2,Oas2,Nampt,Psd4,Cacybp,Ascc3 |
| 1.548e-02 | -4.17 | GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT | 93 | 14 | 15632 | 1249 |
Cacna1d,Ccl4,Tspo,Cxcl10,Hap1,Hspa2,Slc9a1,Pdgfb,Cav1,Homer1,Pdgfrb,Ccr1,Ccl5,Ccl12 |
| 1.548e-02 | -4.17 | GO_NEURAL_TUBE_FORMATION | MSigDB lists | GO_NEURAL_TUBE_FORMATION | 93 | 14 | 15632 | 1249 |
Vasp,Phactr4,Ift57,Fzd1,Ptch1,Lmo4,Mthfd1l,Apaf1,Lhx2,Sec24b,Sdc4,Hif1a,Tulp3,Sema4c |
| 1.549e-02 | -4.17 | PID_CMYB_PATHWAY | MSigDB lists | PID_CMYB_PATHWAY | 84 | 13 | 15632 | 1249 |
Pim1,Tab2,Ptgs2,Adora2b,Kitl,Cd34,Cdkn1a,Tfec,Birc3,Ets2,Myc,Cebpd,Ccnd1 |
| 1.549e-02 | -4.17 | GO_POSITIVE_REGULATION_OF_VIRAL_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_VIRAL_PROCESS | 84 | 13 | 15632 | 1249 |
Polr2g,Adar,Chmp4b,Stau1,Notch1,Mdfic,Larp1,Trim21,Pcx,Ifit1bl2,Ifit1bl1,Ccl5,Jun |
| 1.558e-02 | -4.16 | CAGGTG_E12_Q6 | MSigDB lists | CAGGTG_E12_Q6 | 2235 | 205 | 15632 | 1249 |
N4bp1,Ehd1,Stk40,Zfp800,Fchsd2,Fut8,Slco3a1,Hif1a,Mthfr,Rhoh,Lif,Cd83,Igsf8,Cnp,Daam1,Sesn3,Ccnj,Tmem26,Csf3,Ube2l6,Pdgfb,Tapbpl,Tcea1,Zhx2,Clic4,Fos,Cxcl14,Ncoa5,Il4i1,Kcnj2,Edn1,Abr,Angpt1,Ltbp2,Rnf19a,Sirt1,Hivep3,Jag1,Adrb2,Pik3cd,Mtmr14,Armc8,Tagap,Cacna1d,Mgat1,Mtus1,Cdyl2,Ntng2,Fabp3,Pigv,Tab2,Csrnp1,Prdm1,Plagl2,Ccdc88b,Ube2f,Map2k1,Fzd5,Ext1,Nr4a3,Frmd4a,Pcgf5,Rtn1,Keap1,Pkp4,Cldnd1,Pcdh7,Cited2,Hmga1,Trip10,Srm,Psip1,Gadd45b,Mid1,Pcx,Gadd45g,Mllt6,S1pr2,Nr1h3,Ubash3b,Palld,Rbl1,Ahr,Spred1,Foxp4,Slamf7,Sdc4,Egln3,Tmem176a,Rap1gap2,Syne2,Atxn7l1,Zeb1,Cacnb3,Odc1,Uaca,Pim2,Ptgir,Hmgcs1,Fam162a,Ust,Rbms1,Znrf1,Swap70,Axl,Atp13a1,Dennd1b,Rffl,Rhoq,Nr3c1,Sell,Jmjd6,Fgr,Apba1,Psme1,Ube2e1,Mcmbp,Crim1,Gch1,Tuba4a,Snx10,Slc7a8,Dgka,Nfkbid,G3bp2,Kif3c,Dusp5,Fndc3a,Ptprj,Dio2,Igf2bp2,Gca,Slc7a11,Pik3r5,Slc44a1,Bbx,Myc,Spry2,Tmtc2,Ccl22,Etv3,Sgms2,Dach1,Abtb2,Slc39a14,St3gal5,Flnb,Bcl9,Irf1,Acvr1b,Il13ra1,Socs3,Igf1r,Sh3bgrl2,Rhbdf2,Bcl6,Arid5a,Armcx6,Errfi1,Arhgap26,Treml2,Tlk2,Itgb8,Rgs3,Fosb,Col11a2,Dusp6,Brd2,Pde4b,Spint2,Eya4,Arl5b,Nrp2,Tmem229b,Phf6,Ppp2r2a,Ets2,Casz1,Ass1,Dhrs9,Sqstm1,Rapgef5,Nr4a1,Dusp4,Dtnb,Cnot4,Vcan,Psd,Arl4a,Sdc1,Cyth3,Stxbp1,Col18a1,Tmem176b,Slc48a1,Kif9,Plod2,Atm,Trib1,Dtx2,Sema4c,Lrrc8c,Pmepa1,Mob3c,Cd82 |
| 1.558e-02 | -4.16 | Tyr_kinase_rcpt_3_CS | interpro domains | IPR001824 | 8 | 3 | 19984 | 1430 |
Flt1,Kdr,Pdgfrb |
| 1.558e-02 | -4.16 | DAD_dom | interpro domains | IPR014767 | 8 | 3 | 19984 | 1430 |
Diaph2,Fmnl2,Daam1 |
| 1.558e-02 | -4.16 | His_Pase_clade-2 | interpro domains | IPR000560 | 8 | 3 | 19984 | 1430 |
Acp2,Minpp1,Acpp |
| 1.561e-02 | -4.16 | Frs2-mediated activation | REACTOME pathways | R-MMU-170968 | 218 | 29 | 8608 | 757 |
Il2rg,Ksr1,Pdgfrb,Ppp2r1b,Map2k1,Jak2,Kitl,Spred1,Pdgfb,Psme2b,Angpt1,Src,Irs2,Ppp2r5a,Rapgef2,Psmb9,Rasgrp1,Dusp5,Psme1,Dusp6,Psmb6,Crkl,Psmb10,Psmb8,Met,Ptk2,Psmd10,Psma6,Psme2 |
| 1.561e-02 | -4.16 | MAPK1/MAPK3 signaling | REACTOME pathways | R-MMU-5684996 | 218 | 29 | 8608 | 757 |
Psmb6,Dusp6,Psme1,Dusp5,Rasgrp1,Psmb9,Rapgef2,Psme2,Psma6,Psmd10,Ptk2,Met,Psmb8,Psmb10,Jak2,Map2k1,Ppp2r1b,Pdgfrb,Ksr1,Il2rg,Il6,Src,Irs2,Ppp2r5a,Angpt1,Psme2b,Pdgfb,Spred1,Kitl |
| 1.563e-02 | -4.16 | GO_LIPID_BINDING | MSigDB lists | GO_LIPID_BINDING | 590 | 62 | 15632 | 1249 |
Pla2g4a,Kcnj2,Stap1,Stard5,Psd,S1pr2,Trip10,F10,Tspo,Mark2,Tlr6,Cyth3,Nr1h3,Fabp7,Slc9a1,Pla2g7,Rasgrp1,S100a8,Cav1,Ptch1,Plekha2,Adap2,Zcchc2,Stard7,C3,Mppe1,Lpar1,Tlr2,Lyn,Nr3c1,Arhgap26,Hspa2,Axl,Plekha5,Itpr1,Traf2,Rnf34,Sgk3,Cd14,Myo10,Apba1,Tulp3,Fabp3,Sell,Wdfy1,Tlr1,Rapgef2,Snx2,Dgka,Plek,Snx10,Psd4,Myo1b,Plekha4,Osbpl3,Thbs1,Mitd1,Cd55,Ptgs2,Fcho2,Nsmaf,Ptafr |
| 1.568e-02 | -4.16 | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_UP | 169 | 22 | 15632 | 1249 |
Inhba,Flnb,Ppp1r15a,Rrs1,4930523C07Rik,Pfkl,Ppfibp2,Dr1,Rbms1,Tax1bp1,Bambi,Kif3c,Mdm2,Gadd45g,Dtnb,Rhoq,Traf2,Rgs14,Cd302,Rras2,Hlx,Plk3 |
| 1.568e-02 | -4.16 | GSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_DN | 169 | 22 | 15632 | 1249 |
Aff1,Crim1,Calcrl,Nxf1,Pikfyve,D1Ertd622e,Nr3c1,Cyfip1,Syk,Rbms1,Mafg,Azi2,Rcsd1,Endod1,Itpkc,Kctd12,Rasgrp1,Il10,Rel,Dusp6,Nfkb1,Sesn3 |
| 1.568e-02 | -4.16 | GO_PLASMA_MEMBRANE_RECEPTOR_COMPLEX | MSigDB lists | GO_PLASMA_MEMBRANE_RECEPTOR_COMPLEX | 169 | 22 | 15632 | 1249 |
Rnf31,Syk,Itgav,Cd40,Birc2,Itgal,Traf2,Tlr1,Itgb8,Il6,Acvr1,Il12rb1,Il13ra1,Tlr6,Itga5,Itga4,Tlr2,Lyn,Itga9,Acvr1b,Bmp2,Traf5 |
| 1.569e-02 | -4.15 | lung morphogenesis | biological process | GO:0060425 | 58 | 9 | 20694 | 1406 |
Lif,Sec24b,Plod3,Tnc,Stk40,Spry2,Hhex,Hmga2,Map2k1 |
| 1.569e-02 | -4.15 | positive regulation of viral life cycle | biological process | GO:1903902 | 58 | 9 | 20694 | 1406 |
Adar,Trim30a,Chmp4b,Notch1,Pcx,Cd74,Trim21,Stau1,Larp1 |
| 1.570e-02 | -4.15 | negative regulation of lipid metabolic process | biological process | GO:0045833 | 88 | 12 | 20694 | 1406 |
Sirt1,Gfi1,Trib3,Bmp2,Il1b,Pde3b,Pdgfb,Sphk1,Nfkb1,Ppp2r5a,Hcar2,Tnf |
| 1.570e-02 | -4.15 | positive regulation of insulin secretion | biological process | GO:0032024 | 88 | 12 | 20694 | 1406 |
Prkce,Irs2,Cacna1d,Hif1a,Gja1,Jak2,Nlgn2,Glrx,Serp1,Sirt1,Cd38,Gpr68 |
| 1.570e-02 | -4.15 | GNF2_DDX5 | MSigDB lists | GNF2_DDX5 | 58 | 10 | 15632 | 1249 |
Phf11d,Birc2,Nxf1,Itga4,Crbn,Phf11b,H3f3b,Tyk2,Phf11c,Phf11a |
| 1.570e-02 | -4.15 | GO_PHOSPHOPROTEIN_BINDING | MSigDB lists | GO_PHOSPHOPROTEIN_BINDING | 58 | 10 | 15632 | 1249 |
Src,Fgr,Lyn,Phf6,Samsn1,Plat,Lrp11,Stap1,Mid1,Acp2 |
| 1.570e-02 | -4.15 | MODULE_418 | MSigDB lists | MODULE_418 | 58 | 10 | 15632 | 1249 |
Cp,Gca,Ifi44,Znrf1,Rhou,Gda,Sele,Cd200,H2-Ab1,Mmp25 |
| 1.570e-02 | -4.15 | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | 58 | 10 | 15632 | 1249 |
Phgdh,Sla,Slc7a5,Wars,Ass1,Slc7a11,Asns,Trib3,Itgal,Mthfd2 |
| 1.570e-02 | -4.15 | BILD_SRC_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_SRC_ONCOGENIC_SIGNATURE | 58 | 10 | 15632 | 1249 |
Lipg,Serpinb2,Extl2,Tnfaip3,Dcbld2,Casp1,Lnpep,Src,Hsph1,Ppp1r15a |
| 1.570e-02 | -4.15 | SESTO_RESPONSE_TO_UV_C7 | MSigDB lists | SESTO_RESPONSE_TO_UV_C7 | 58 | 10 | 15632 | 1249 |
Ctsc,Pla2g4a,Cebpd,Esd,Lif,Ass1,Acsl1,Odc1,Asns,Sdc1 |
| 1.570e-02 | -4.15 | MODULE_199 | MSigDB lists | MODULE_199 | 58 | 10 | 15632 | 1249 |
Cdk5r1,Pdgfrb,Csf3r,Il4ra,Il2rg,Il13ra1,Ccl12,Axl,Cdkn1a,Kdr |
| 1.570e-02 | -4.15 | BILBAN_B_CLL_LPL_UP | MSigDB lists | BILBAN_B_CLL_LPL_UP | 58 | 10 | 15632 | 1249 |
Slc39a14,Oas1a,Oas2,Tbc1d1,Irf4,Flnb,Gpr18,Pim1,4930523C07Rik,Oas1g |
| 1.570e-02 | -4.15 | CEBP_01 | MSigDB lists | CEBP_01 | 239 | 29 | 15632 | 1249 |
Cd86,Samsn1,Fosb,Jarid2,Plek,Map4k4,Rnf19a,Syne2,Nr4a3,Cpeb4,Kpna3,Slc31a1,Rbms1,Gcnt2,Thbs1,Tnfsf10,Tnf,Tra2a,Ythdf1,Fut8,Nr3c1,Egr2,Dusp2,Arrdc4,Prdm1,Nfkbiz,Palld,Rgs3,Pde3b |
| 1.571e-02 | -4.15 | positive regulation of protein binding | biological process | GO:0032092 | 109 | 14 | 20694 | 1406 |
Trib3,Agrn,Bmp2,Plcl2,Rapgef2,Dtx3l,Plk2,Csf3,Mmp9,Ripk2,Cav1,Crbn,Traf2,Bambi |
| 1.574e-02 | -4.15 | AUF1 (hnRNP D0) binds and destabilizes mRNA | REACTOME pathways | R-MMU-450408 | 53 | 10 | 8608 | 757 |
Psmb6,Psme2,Psma6,Psmd10,Hspa1b,Psme1,Psme2b,Psmb8,Psmb9,Psmb10 |
| 1.578e-02 | -4.15 | GO_REGULATION_OF_CHROMATIN_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_CHROMATIN_ORGANIZATION | 140 | 19 | 15632 | 1249 |
Kdm4a,Kat2b,Parp10,Mthfr,Bcor,Pml,Lif,Daxx,Il1b,Gfi1,Asf1a,Hmga1,Bcl6,Atm,Jarid2,Jdp2,Mecp2,Sirt1,Tlk2 |
| 1.578e-02 | -4.15 | IGLESIAS_E2F_TARGETS_UP | MSigDB lists | IGLESIAS_E2F_TARGETS_UP | 140 | 19 | 15632 | 1249 |
Cd34,Kitl,Thbs1,Cd74,Ccnd2,Gbp3,Evl,Col18a1,C3,Cnn3,Sat1,Cyfip1,Cacybp,Dnaja1,Tank,Nfkbia,Gadd45b,Csrp1,Gja1 |
| 1.581e-02 | -4.15 | response to nitric oxide | biological process | GO:0071731 | 15 | 4 | 20694 | 1406 |
Cflar,Thbs1,Traf2,Itgav |
| 1.581e-02 | -4.15 | regulation of integrin activation | biological process | GO:0033623 | 15 | 4 | 20694 | 1406 |
Plek,Piezo1,Ptger4,P2ry12 |
| 1.581e-02 | -4.15 | cellular response to copper ion | biological process | GO:0071280 | 15 | 4 | 20694 | 1406 |
Daxx,Prnp,Mt2,Mt1 |
| 1.581e-02 | -4.15 | neurotrophin TRK receptor signaling pathway | biological process | GO:0048011 | 15 | 4 | 20694 | 1406 |
Src,Casp3,Ddit4,Hap1 |
| 1.581e-02 | -4.15 | regulation of RIG-I signaling pathway | biological process | GO:0039535 | 15 | 4 | 20694 | 1406 |
Ankrd17,Zc3hav1,Ddx60,Dhx58 |
| 1.581e-02 | -4.15 | regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | biological process | GO:2001267 | 15 | 4 | 20694 | 1406 |
Plaur,Jak2,Fas,Mmp9 |
| 1.581e-02 | -4.15 | regulation of vitamin metabolic process | biological process | GO:0030656 | 15 | 4 | 20694 | 1406 |
Nfkb1,Gfi1,Il1b,Tnf |
| 1.581e-02 | -4.15 | cellular copper ion homeostasis | biological process | GO:0006878 | 15 | 4 | 20694 | 1406 |
Sco1,Prnp,Slc31a2,Slc31a1 |
| 1.581e-02 | -4.15 | neuron remodeling | biological process | GO:0016322 | 15 | 4 | 20694 | 1406 |
C3,Pdgfb,Scarf1,Rnd1 |
| 1.581e-02 | -4.15 | positive regulation of T cell differentiation in thymus | biological process | GO:0033089 | 15 | 4 | 20694 | 1406 |
Il2rg,Il1b,Egr3,Rasgrp1 |
| 1.581e-02 | -4.15 | positive regulation of glutamate secretion | biological process | GO:0014049 | 15 | 4 | 20694 | 1406 |
Adora2a,Stxbp1,Kmo,Nr3c1 |
| 1.581e-02 | -4.15 | positive regulation of cell growth involved in cardiac muscle cell development | biological process | GO:0061051 | 15 | 4 | 20694 | 1406 |
Trip10,Nr3c1,Edn1,Sirt1 |
| 1.584e-02 | -4.15 | GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT | MSigDB lists | GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT | 385 | 43 | 15632 | 1249 |
Pla2g4a,Mmp14,Bcl2l11,Tiparp,Ahr,Fas,Sdc1,Htra1,Sirt1,Casp2,Ccne1,Il10,Casp8,Hmgcs1,Ptk2,Socs3,Tnc,Itgb8,Kdm5b,Ccnd1,Src,Axl,Plekha5,Insl6,Birc2,Notch1,Prdm1,Nupr1,Lif,Hif1a,Icam1,Pdgfb,Inhba,Mmp13,Arid4a,Junb,Fzd5,Map2k1,Kitl,Tlr3,Fndc3a,Ptgs2,Arid5b |
| 1.584e-02 | -4.15 | GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_DN | MSigDB lists | GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_DN | 179 | 23 | 15632 | 1249 |
Fam53c,Herc6,Irf2,Egr3,Trim12c,Arrdc4,Pgm1,Cd180,Clcn7,Ap3m2,Zfp319,Sqstm1,Klf3,Spsb1,Nampt,Arid5a,Pid1,Ccl2,Batf2,Csf1,Stx6,Rsad2,Leng9 |
| 1.584e-02 | -4.15 | GSE40273_EOS_KO_VS_WT_TREG_UP | MSigDB lists | GSE40273_EOS_KO_VS_WT_TREG_UP | 179 | 23 | 15632 | 1249 |
Ccne1,Slpi,St3gal1,Slc31a1,Rcn1,Tlr2,Tapbpl,Gfpt1,Slc37a3,Plod3,Tet2,Tpst1,Irgm2,Stard5,Cers6,Pml,Nek6,Gmppb,Dtwd1,Sgcb,Sla,Slc48a1,Cd38 |
| 1.584e-02 | -4.15 | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_UP | MSigDB lists | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_UP | 179 | 23 | 15632 | 1249 |
Ifit1,Igf1r,Tfec,Sh3bgrl2,Adar,Kmo,Tmtc2,Kcna3,Cxcl10,Evl,Kdm6b,Rtn1,Rapgef2,Rnf19a,Syne2,Kctd12,Gsr,Gpr84,H2-Aa,Otud1,Rims3,Hivep2,Map3k6 |
| 1.584e-02 | -4.15 | GSE27786_NKTCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_NKTCELL_VS_MONO_MAC_UP | 179 | 23 | 15632 | 1249 |
Gpr68,Xaf1,Cox17,Taf4b,G3bp2,Spry2,Inpp5b,Rab10,Lap3,Cacybp,Brd2,Tshz1,Mthfd1l,Tap1,Zc3hav1,Ppp2r2a,Stip1,Rbms2,Ttc39b,Pttg1,Cox18,Rnf145,Smc5 |
| 1.584e-02 | -4.15 | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP | MSigDB lists | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP | 179 | 23 | 15632 | 1249 |
Lrrc8c,Clcn5,Slc48a1,Ccl4,Cacna1d,Osbpl3,Gpd2,Spata13,Dusp5,Lrp8,Xkr8,Endod1,Prdm1,Casp7,Rap1gap2,Il18rap,Vasn,Smpdl3b,Fcgr2b,Myadm,Clic5,Cx3cr1,Cdyl |
| 1.584e-02 | -4.15 | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_UP | MSigDB lists | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_UP | 179 | 23 | 15632 | 1249 |
Plac8,Psmb10,St3gal6,Gmppb,Ripk3,Ahsa1,Slc16a1,Lap3,Pdk3,Plek,Psat1,Hk2,Trip13,Noc4l,Tapbpl,Mthfd2,Slc43a3,Irf1,Pim2,Ppa1,Rcl1,Lrp11,Ccl4 |
| 1.584e-02 | -4.15 | GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_DN | 179 | 23 | 15632 | 1249 |
Tmem176b,Prdm1,Etnk1,Ppa1,Pttg1,Atp11a,Tab2,F11r,Nxf1,Azi2,Col4a2,Pnpt1,Gng12,Mvp,Ezr,Plac8,Map4k4,Tiparp,Lcn2,Caml,Ccdc86,Pla2g7,Ifrd1 |
| 1.584e-02 | -4.15 | GSE11924_TH1_VS_TH2_CD4_TCELL_DN | MSigDB lists | GSE11924_TH1_VS_TH2_CD4_TCELL_DN | 179 | 23 | 15632 | 1249 |
Slpi,Caml,Il12rb1,Snx2,Gja1,Hsd17b12,Golga3,Daam1,Gfpt1,Arf4,Gfi1,Rcl1,Nr3c1,Ccr3,Prdx5,Casp1,Rnd3,Slfn5,Mvp,Aff1,Col18a1,St3gal6,Tmtc2 |
| 1.584e-02 | -4.15 | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY6_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY6_EFFECTOR_CD8_TCELL_UP | 179 | 23 | 15632 | 1249 |
Pttg1,Magohb,Pml,Rras2,Plac8,Hivep2,Agrn,Cdyl2,Mlkl,Katna1,Aftph,Ptprj,Kpna3,Kdm6b,Psmb6,Trafd1,Gfi1,Irf7,Txn1,Slamf9,Eef1e1,Inpp5b,Nfkbib |
| 1.586e-02 | -4.14 | carboxylic acid biosynthetic process | biological process | GO:0046394 | 233 | 25 | 20694 | 1406 |
Ptges,Sphk1,Edn1,Plod2,Cd74,Dhrs9,Nr1h3,Kmo,Il1b,Plod3,Lipg,Tha1,Mthfd1l,Phgdh,Ptgs2,Syk,Mthfr,Asah2,Ass1,Gch1,Pla2g4a,Dse,Psat1,Ldha,Asns |
| 1.587e-02 | -4.14 | His_Phos_2 | pfam domains | PF00328 | 8 | 3 | 18711 | 1348 |
Acp2,Acpp,Minpp1 |
| 1.592e-02 | -4.14 | CEBPA_01 | MSigDB lists | CEBPA_01 | 219 | 27 | 15632 | 1249 |
Cd55,Trib1,Gpr85,Adrb2,H3f3b,Hcar2,Jarid2,Asah2,Lmo4,Zeb1,Pdgfb,Nrp2,Ube2e2,Slc25a12,Prdm1,Pigv,Arrdc4,Gys1,Rab3ip,Notch1,Crim1,Spred1,Gypc,Bcl6,Pla2g4a,Kcnj2,Rhoq |
| 1.594e-02 | -4.14 | GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP | MSigDB lists | GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP | 189 | 24 | 15632 | 1249 |
Slc44a1,Mmp14,Acpp,Spsb1,Nfkbia,Agrn,Plod3,Gnb4,Sgcb,1600014C10Rik,Nkiras1,Pttg1,Slc30a1,Nxf1,Evl,Tlr6,Rnf19a,Itgal,Lmo4,Eno2,Jarid2,Rnf14,Cdkn1a,Glrx |
| 1.594e-02 | -4.14 | GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_DN | 189 | 24 | 15632 | 1249 |
Mapkapk2,Cd180,Kif9,Gys1,Cd80,Itgav,Cd302,Tpst1,Rab11fip1,Rhoq,Acvrl1,Endod1,Casp7,Fndc3a,Osbpl3,Tnfaip2,Armc8,Slc31a2,Slc12a9,Gna15,Bcl9,Rab10,Plscr1,Tyk2 |
| 1.594e-02 | -4.14 | GSE27786_ERYTHROBLAST_VS_MONO_MAC_UP | MSigDB lists | GSE27786_ERYTHROBLAST_VS_MONO_MAC_UP | 189 | 24 | 15632 | 1249 |
Uba7,Xaf1,Rnf19a,Sirt1,Dmwd,Daam1,Ccne1,Cmpk2,Dio2,Fam162a,Pcdh7,Frmd4a,Slc43a3,Dck,Smox,Egr3,Carhsp1,Stau1,Sass6,St3gal6,Sertad3,Nmral1,Prnp,Pml |
| 1.594e-02 | -4.14 | GSE43955_1H_VS_10H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_1H_VS_10H_ACT_CD4_TCELL_UP | 189 | 24 | 15632 | 1249 |
Stip1,Dusp16,Plaur,Thbs1,Fam20c,Ccl4,Tnip1,Bcl2a1a,Gtpbp2,Ell2,Noc4l,Gem,Traf1,Gmppb,Tpi1,Ch25h,Cebpd,Bcl2a1d,Fcgr2b,Ctsc,Tank,Msr1,Bcl2a1b,Tnf |
| 1.596e-02 | -4.14 | ABC_TM1F | prosite domains | PS50929 | 27 | 6 | 13278 | 1037 |
Tap1,Abcc5,Abcc4,Tap2,Abcc1,Abcb1a |
| 1.596e-02 | -4.14 | bicellular tight junction | cellular component | GO:0005923 | 120 | 15 | 20747 | 1409 |
Cyth3,Ccnd1,Mtdh,Usp53,Rapgef2,Ddx58,Clmp,Vasp,Mpp7,Rap2c,Micall2,Rpgrip1l,Fzd5,F11r,Frmd4a |
| 1.601e-02 | -4.13 | Regulation of TP53 Expression and Degradation | REACTOME pathways | R-MMU-6806003 | 31 | 7 | 8608 | 757 |
Atm,Mdm2,Daxx,Ppp2r1b,Rictor,Rffl,Rnf34 |
| 1.601e-02 | -4.13 | Regulation of TP53 Degradation | REACTOME pathways | R-MMU-6804757 | 31 | 7 | 8608 | 757 |
Ppp2r1b,Rffl,Rictor,Rnf34,Mdm2,Daxx,Atm |
| 1.602e-02 | -4.13 | positive regulation of peptide hormone secretion | biological process | GO:0090277 | 120 | 15 | 20694 | 1406 |
Ptger4,Lif,Nlgn2,Hif1a,Jak2,Gja1,Irs2,Cacna1d,Prkce,Clcf1,Gpr68,Cd38,Sirt1,Serp1,Glrx |
| 1.604e-02 | -4.13 | regulation of muscle contraction | biological process | GO:0006937 | 153 | 18 | 20694 | 1406 |
Adrb2,Pde4b,Slc9a1,Pde5a,Zc3h12a,Adora2b,Kcnj2,Map2k1,Agrn,Ptger4,Sphk1,Arg2,Ptafr,Edn1,Calcrl,Cav1,Dock4,Ptgs2 |
| 1.605e-02 | -4.13 | drug transmembrane transport | biological process | GO:0006855 | 68 | 10 | 20694 | 1406 |
Stra6l,Slc31a1,Slc7a2,Abcb1a,Slc25a12,Abcc4,Slc13a3,Abcc1,Slc7a11,Slc25a22 |
| 1.615e-02 | -4.13 | AMUNDSON_DNA_DAMAGE_RESPONSE_TP53 | MSigDB lists | AMUNDSON_DNA_DAMAGE_RESPONSE_TP53 | 13 | 4 | 15632 | 1249 |
Mdm2,Cdkn1a,Btg2,Lif |
| 1.615e-02 | -4.13 | MODULE_516 | MSigDB lists | MODULE_516 | 13 | 4 | 15632 | 1249 |
Tnfaip2,Angpt1,Il18,Jag1 |
| 1.615e-02 | -4.13 | GO_NEGATIVE_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 13 | 4 | 15632 | 1249 |
Mdm2,Cd74,Psmd10,Sirt1 |
| 1.615e-02 | -4.13 | GO_NEGATIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING | 13 | 4 | 15632 | 1249 |
Plek,Prnp,Itpr1,Atp2b4 |
| 1.615e-02 | -4.13 | GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 13 | 4 | 15632 | 1249 |
Il4ra,Fgr,Adora2b,Syk |
| 1.615e-02 | -4.13 | MODULE_412 | MSigDB lists | MODULE_412 | 13 | 4 | 15632 | 1249 |
Itgal,Itgav,Itga5,Tnc |
| 1.615e-02 | -4.13 | GO_REGULATION_OF_PROTEIN_HOMOOLIGOMERIZATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_HOMOOLIGOMERIZATION | 13 | 4 | 15632 | 1249 |
Bcl2l11,Fas,Src,Crbn |
| 1.615e-02 | -4.13 | PARK_APL_PATHOGENESIS_UP | MSigDB lists | PARK_APL_PATHOGENESIS_UP | 13 | 4 | 15632 | 1249 |
Psme2,Ahr,Psmb9,Stip1 |
| 1.615e-02 | -4.13 | MODULE_262 | MSigDB lists | MODULE_262 | 13 | 4 | 15632 | 1249 |
Myc,Ccl2,Ccl12,Cp |
| 1.615e-02 | -4.13 | HEIDENBLAD_AMPLIFIED_IN_SOFT_TISSUE_CANCER | MSigDB lists | HEIDENBLAD_AMPLIFIED_IN_SOFT_TISSUE_CANCER | 13 | 4 | 15632 | 1249 |
Src,Jun,Tab2,Mdm2 |
| 1.615e-02 | -4.13 | GO_CELLULAR_COPPER_ION_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_COPPER_ION_HOMEOSTASIS | 13 | 4 | 15632 | 1249 |
Slc31a1,Slc31a2,Sco1,Prnp |
| 1.615e-02 | -4.13 | BIOCARTA_ERYTH_PATHWAY | MSigDB lists | BIOCARTA_ERYTH_PATHWAY | 13 | 4 | 15632 | 1249 |
Csf3,Il1a,Kitl,Il6 |
| 1.615e-02 | -4.13 | SANCHEZ_MDM2_TARGETS | MSigDB lists | SANCHEZ_MDM2_TARGETS | 13 | 4 | 15632 | 1249 |
Il1rn,Ccnd1,Timp1,Cdkn1a |
| 1.615e-02 | -4.13 | MODULE_465 | MSigDB lists | MODULE_465 | 13 | 4 | 15632 | 1249 |
Pde3b,Dusp6,Srxn1,Fpr1 |
| 1.615e-02 | -4.13 | HUMMERICH_MALIGNANT_SKIN_TUMOR_UP | MSigDB lists | HUMMERICH_MALIGNANT_SKIN_TUMOR_UP | 13 | 4 | 15632 | 1249 |
S100a8,Slpi,Col18a1,Ccnd1 |
| 1.615e-02 | -4.13 | GO_NEGATIVE_REGULATION_OF_MONOOXYGENASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MONOOXYGENASE_ACTIVITY | 13 | 4 | 15632 | 1249 |
Gfi1,Atp2b4,Cav1,Nfkb1 |
| 1.618e-02 | -4.12 | TAATGTG_MIR323 | MSigDB lists | TAATGTG_MIR323 | 150 | 20 | 15632 | 1249 |
G3bp2,Cept1,Ccnd1,Rab10,Nfkb1,Gja1,Map4k4,Pkp4,Atp11b,Rsbn1,Rpgrip1l,Asf1a,Fcho2,Rcn1,Intu,Nr4a3,Cpeb4,Egr3,Kpna3,Marcksl1 |
| 1.618e-02 | -4.12 | GO_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS | 150 | 20 | 15632 | 1249 |
Irs2,Ptafr,Kat2b,Hif1a,Dyrk2,Ptger4,Htr2a,Gfpt1,Il15,Ptpn2,Nfkb1,Src,Plek,Pdk3,Sirt1,Il6,Prkce,Stat3,Pdgfb,Ddit4 |
| 1.619e-02 | -4.12 | protein tyrosine phosphatase activity | molecular function | GO:0004725 | 97 | 13 | 20217 | 1400 |
Dusp5,Dusp8,Ubash3b,Dusp28,Ptprj,Eya4,Mtmr14,Dusp2,Dusp6,Ptpn2,Dusp4,Dusp14,Dusp1 |
| 1.625e-02 | -4.12 | GSE40274_FOXP3_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 112 | 16 | 15632 | 1249 |
Kat2b,Fas,Aim2,Cd55,Slc37a3,Fbxo4,Clcf1,Cep350,Vps54,Nfkbia,Arid4a,Il18bp,Treml2,Prkce,Tnfsf8,Il6 |
| 1.626e-02 | -4.12 | GO_NEURON_APOPTOTIC_PROCESS | MSigDB lists | GO_NEURON_APOPTOTIC_PROCESS | 34 | 7 | 15632 | 1249 |
Fas,Max,Atm,Apaf1,Fam162a,Bnip3,Casp3 |
| 1.626e-02 | -4.12 | PID_EPHA_FWDPATHWAY | MSigDB lists | PID_EPHA_FWDPATHWAY | 34 | 7 | 15632 | 1249 |
Hck,Crkl,Src,Pik3r5,Pik3r6,Lyn,Fgr |
| 1.626e-02 | -4.12 | GO_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | MSigDB lists | GO_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | 34 | 7 | 15632 | 1249 |
Cd200,Itga5,Icam1,Itgal,Vcam1,Cd164,Sele |
| 1.632e-02 | -4.12 | Cellular Senescence | REACTOME pathways | R-MMU-2559583 | 137 | 20 | 8608 | 757 |
Jun,Ets2,Mapkapk2,Hmga2,Asf1a,Cdkn2d,Atm,H3f3b,Hmga1,Ccne1,Fos,Ep400,Ube2e1,Il6,Kdm6b,Cdkn1a,Txn1,Map2k4,Nfkb1,Mdm2 |
| 1.637e-02 | -4.11 | GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 50 | 9 | 15632 | 1249 |
Inhba,Ppp2r1b,Tnfsf10,Thbs1,Cav1,Traf2,Pml,Fas,Atf3 |
| 1.642e-02 | -4.11 | GCM_PTK2 | MSigDB lists | GCM_PTK2 | 131 | 18 | 15632 | 1249 |
Spire1,Ptk2,Kif5c,Fmnl2,Pkp4,Agpat4,Myo10,Cldnd1,Ankrd17,Tmem184b,Sik3,Rabgef1,Sesn3,Map4k4,4932438A13Rik,Arhgap26,Ociad1,Phlpp2 |
| 1.642e-02 | -4.11 | GSE15624_3H_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_DN | MSigDB lists | GSE15624_3H_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_DN | 131 | 18 | 15632 | 1249 |
Rgs1,Crim1,Pfkl,Gbp2,Larp1,Lif,Psmb6,Parp3,Csrnp1,Rnf145,Trim26,Stat3,Aebp2,Usp12,Tapbp,Birc3,Sesn3,Rnf114 |
| 1.642e-02 | -4.11 | GO_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE | MSigDB lists | GO_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE | 131 | 18 | 15632 | 1249 |
Hhex,Pml,Notch1,Clic4,Pbx1,Bmp2,Ptch1,Src,Acvr1,Kdm5b,Met,Edn1,Spry2,Tnc,Csf1,Myc,Mmp14,Timeless |
| 1.642e-02 | -4.11 | STAT3_02 | MSigDB lists | STAT3_02 | 131 | 18 | 15632 | 1249 |
Fut8,Il18bp,Ncoa5,Nr4a1,Trip10,Fosb,Smg7,Mob3c,Rgs3,Zhx2,Egr3,Mtmr14,Egr1,Tmem229b,Sdc1,Irf1,Rnd1,Socs1 |
| 1.648e-02 | -4.11 | GO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | GO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 281 | 33 | 15632 | 1249 |
Dock10,Rin2,Psd,Dennd1b,Trip10,Dock4,P2ry12,Arhgef3,Rapgef5,Angpt1,Rab3ip,Irs2,Spata13,Cyth3,Abr,Nck1,Rasgrp1,Rapgef2,Pdgfb,Pdgfrb,Plekhg1,Psd4,Rabgef1,Rgl1,Tagap,Ralgds,Kitl,Arf4,Jak2,Il2rg,Ptgir,Dennd2a,Ptk2 |
| 1.648e-02 | -4.11 | PID_VEGFR1_2_PATHWAY | MSigDB lists | PID_VEGFR1_2_PATHWAY | 67 | 11 | 15632 | 1249 |
Cav1,Ptpn2,Map2k1,Ptprj,Src,Nck1,Flt1,Ptk2,Mapkapk2,Itgav,Kdr |
| 1.648e-02 | -4.11 | GO_NUCLEOSIDE_PHOSPHATE_CATABOLIC_PROCESS | MSigDB lists | GO_NUCLEOSIDE_PHOSPHATE_CATABOLIC_PROCESS | 67 | 11 | 15632 | 1249 |
Upp1,Samhd1,Gda,Pde3b,Cnp,Pde4b,Pde5a,Pde7b,Pnp2,Ampd3,Pde1b |
| 1.648e-02 | -4.11 | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_UP | MSigDB lists | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_UP | 160 | 21 | 15632 | 1249 |
Maff,Spint2,Rbpms,Pnp2,Bnip3,Abcb1a,Plod2,C1rl,Plekha2,Trip10,Samsn1,Csrp1,Birc3,Hsd17b12,Tle3,Angpt1,Cd164,Lyn,Spire1,Calcrl,Itga9 |
| 1.648e-02 | -4.11 | GSE40274_IRF4_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_IRF4_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 160 | 21 | 15632 | 1249 |
Ccrl2,Dgka,Vasp,Slc9a1,Cnp,Ppp1r14b,Trafd1,Glrx,Actb,Nfkb2,Rap2c,Hcls1,Tspo,Spata13,Mppe1,Azi2,Nr4a3,Jmjd6,Ifi35,Nck1,Rhoh |
| 1.648e-02 | -4.11 | GSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_UP | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_UP | 160 | 21 | 15632 | 1249 |
Tra2a,Rap1gap2,Tnfsf8,Setdb2,Ppp4r2,Rnaset2a,Ppp1r15a,Rhbdf2,Zyx,Txn1,Spryd7,Sod2,Clec4a1,Rnaset2b,Vrk2,Rnf34,Ralgds,Tax1bp1,Rnf145,Upp1,Xrn1 |
| 1.648e-02 | -4.11 | GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 160 | 21 | 15632 | 1249 |
Ctsc,Fgl2,Rin2,Jag1,Syne2,Rab32,Ttc9c,Ezr,Bcl6,Cd302,Hcls1,Pdgfc,Fmnl2,Glrx,Slc28a2,Malt1,Tlr3,Cd200,Tmem229b,Frmd4a,Rcsd1 |
| 1.649e-02 | -4.11 | protein polyubiquitination | biological process | GO:0000209 | 176 | 20 | 20694 | 1406 |
Trim21,Rnf34,Traf2,Birc2,Ube2e2,Znrf1,Rnf14,Ankib1,Ube2e1,Tnfaip3,Rffl,Peli1,Fbxo4,Rnf31,Dtx3l,Bfar,Arel1,Rnf19a,Rnf19b,Trim56 |
| 1.651e-02 | -4.10 | negative regulation of myoblast differentiation | biological process | GO:0045662 | 31 | 6 | 20694 | 1406 |
Cxcl10,Tnf,Cxcl14,Ccl9,Il18,Notch1 |
| 1.651e-02 | -4.10 | negative regulation of blood vessel endothelial cell migration | biological process | GO:0043537 | 31 | 6 | 20694 | 1406 |
Spred1,Mecp2,Thbs1,Notch1,Rgcc,Acvrl1 |
| 1.651e-02 | -4.10 | negative regulation of exocytosis | biological process | GO:0045920 | 31 | 6 | 20694 | 1406 |
Notch1,Hmox1,Stxbp3,Rabgef1,Abr,Lgals9 |
| 1.651e-02 | -4.10 | negative regulation of endothelial cell apoptotic process | biological process | GO:2000352 | 31 | 6 | 20694 | 1406 |
Icam1,Tnfaip3,Serpine1,Il10,Kdr,Angpt1 |
| 1.651e-02 | -4.10 | maternal placenta development | biological process | GO:0001893 | 31 | 6 | 20694 | 1406 |
Junb,Lif,Cited2,Prdm1,Pla2g4a,Ptgs2 |
| 1.651e-02 | -4.10 | negative regulation of cardiac muscle hypertrophy | biological process | GO:0010614 | 31 | 6 | 20694 | 1406 |
Jarid2,Atp2b4,Tomm70a,Errfi1,Notch1,Tnfrsf1b |
| 1.651e-02 | -4.10 | regulation of neutrophil chemotaxis | biological process | GO:0090022 | 31 | 6 | 20694 | 1406 |
Bst1,Edn1,Il1b,Cd74,Nod2,Sell |
| 1.651e-02 | -4.10 | negative regulation of signal transduction by p53 class mediator | biological process | GO:1901797 | 31 | 6 | 20694 | 1406 |
Sirt1,Psmd10,Rnf34,Cd74,Rffl,Mdm2 |
| 1.651e-02 | -4.10 | positive regulation of neurotransmitter secretion | biological process | GO:0001956 | 31 | 6 | 20694 | 1406 |
Sphk1,Ptger4,Stxbp1,Cacna1d,Kmo,Adora2a |
| 1.652e-02 | -4.10 | Kdr (kinase insert domain protein receptor) | protein interactions | 16542 | 11 | 4 | 7778 | 753 |
Kdr,Met,Src,Nck1 |
| 1.652e-02 | -4.10 | SOD1 (superoxide dismutase 1) | protein interactions | 6647 | 11 | 4 | 7778 | 753 |
Hspa1b,Hsph1,Dnaja1,Hspa2 |
| 1.652e-02 | -4.10 | Mavs (mitochondrial antiviral signaling protein) | protein interactions | 228607 | 11 | 4 | 7778 | 753 |
Ikbkg,Traf5,Tax1bp1,Traf2 |
| 1.652e-02 | -4.10 | Brap (BRCA1 associated protein) | protein interactions | 72399 | 11 | 4 | 7778 | 753 |
Phlpp1,Syne2,Map2k1,Ksr1 |
| 1.655e-02 | -4.10 | Caspase-mediated cleavage of cytoskeletal proteins | REACTOME pathways | R-MMU-264870 | 12 | 4 | 8608 | 757 |
Casp3,Dbnl,Casp7,Casp8 |
| 1.655e-02 | -4.10 | Formation of Senescence-Associated Heterochromatin Foci (SAHF) | REACTOME pathways | R-MMU-2559584 | 12 | 4 | 8608 | 757 |
Asf1a,Hmga1,Ep400,Hmga2 |
| 1.658e-02 | -4.10 | transcription by RNA polymerase II | biological process | GO:0006366 | 199 | 22 | 20694 | 1406 |
Nmi,Taf4b,Stat3,Med21,Ell2,Jun,Tcf4,Stat5a,Fos,Egr2,Hif1a,Nfil3,Fosb,Med13,Pttg1,Polr2g,Junb,Myc,Egr1,Ahr,Snapc1,Lmo4 |
| 1.659e-02 | -4.10 | TNFR_NGFR_2 | prosite domains | PS50050 | 20 | 5 | 13278 | 1037 |
Tnfrsf8,Tnfrsf14,Cd40,Tnfrsf1b,Fas |
| 1.659e-02 | -4.10 | B cell proliferation | biological process | GO:0042100 | 49 | 8 | 20694 | 1406 |
Ifna1,Ifna5,Ifna2,Ifna6,Plcl2,Ifnb1,Ifna4,Cd180 |
| 1.659e-02 | -4.10 | neuron apoptotic process | biological process | GO:0051402 | 49 | 8 | 20694 | 1406 |
Fam162a,Casp7,Fas,Usp53,Apaf1,Bnip3,Atm,Casp3 |
| 1.659e-02 | -4.10 | positive regulation of mRNA catabolic process | biological process | GO:0061014 | 49 | 8 | 20694 | 1406 |
Zc3hav1,Polr2g,Pnpt1,Btg2,Mov10,Zc3h12a,Plekhn1,Zfp36 |
| 1.659e-02 | -4.10 | negative regulation of blood vessel diameter | biological process | GO:0097756 | 49 | 8 | 20694 | 1406 |
Pdgfb,Htr2a,Cd38,Edn1,Ednrb,Htr2b,Cav1,Ptgs2 |
| 1.662e-02 | -4.10 | cell morphogenesis | biological process | GO:0000902 | 746 | 66 | 20694 | 1406 |
Palld,Notch1,Axl,Spint2,Ptch1,Itgav,Gja1,Flrt3,Flnb,Dbnl,Nr4a3,Cdk5r1,Ahr,Klf7,Src,Sema3c,Nrp2,Lhx2,Map4k4,Map2k1,Dock10,Lst1,Sema4a,Micall2,Rilpl1,Nes,Scn1b,Dst,Cyfip1,Vasp,Lrp4,Psmb10,Actb,Plod3,Bcl6,Sec24b,Itga4,Agrn,Rac3,Clic5,Ptk2,Tsku,Ntng2,Ext1,Triobp,Igf1r,Klf2,Antxr1,Clic4,Rab10,Lrp8,Flrt2,Uchl1,Frmd6,Col18a1,Met,Evl,Sdc2,Cnp,Stxbp1,Kif5c,Egr2,Kdr,Snx2,Adora2a,Pdpn |
| 1.663e-02 | -4.10 | REACTOME_G1_S_TRANSITION | MSigDB lists | REACTOME_G1_S_TRANSITION | 103 | 15 | 15632 | 1249 |
Mcm6,Psmb10,Max,Psme1,Mcm10,Psmb6,Cdkn1a,Ppp2r1b,Psmb9,Psmd10,Psmb8,Ccne1,Psma6,Psme2,Myc |
| 1.663e-02 | -4.10 | MODULE_427 | MSigDB lists | MODULE_427 | 103 | 15 | 15632 | 1249 |
Acp2,Cebpd,Snx2,Cish,Pilrb1,Pilrb2,Zeb1,Pfkfb3,Aldh1b1,Frmd4a,Hspa1a,Timp1,Rnf139,Ifi35,Crbn |
| 1.664e-02 | -4.10 | BCAT_GDS748_UP | MSigDB lists | BCAT_GDS748_UP | 42 | 8 | 15632 | 1249 |
Kctd12,Gadd45g,Itga9,Slc39a14,Gch1,Bambi,Abcb1a,Hhex |
| 1.664e-02 | -4.10 | REACTOME_IL_3_5_AND_GM_CSF_SIGNALING | MSigDB lists | REACTOME_IL_3_5_AND_GM_CSF_SIGNALING | 42 | 8 | 15632 | 1249 |
Il2rg,Lyn,Pik3cd,Syk,Crkl,Stat5a,Hck,Jak2 |
| 1.664e-02 | -4.10 | GO_EPITHELIAL_CELL_MORPHOGENESIS | MSigDB lists | GO_EPITHELIAL_CELL_MORPHOGENESIS | 42 | 8 | 15632 | 1249 |
Col18a1,Plod3,Palld,Flnb,Clic4,Rilpl1,Met,Frmd6 |
| 1.664e-02 | -4.10 | OHGUCHI_LIVER_HNF4A_TARGETS_UP | MSigDB lists | OHGUCHI_LIVER_HNF4A_TARGETS_UP | 42 | 8 | 15632 | 1249 |
Hspa2,Ifi44,Il1rn,Abcb1a,Usp18,Psat1,Dram1,Gadd45b |
| 1.664e-02 | -4.10 | GO_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_CELL_DEATH | MSigDB lists | GO_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_CELL_DEATH | 42 | 8 | 15632 | 1249 |
Sirt1,Met,Hsph1,Txn1,Nox1,Sod2,Hif1a,Nr4a3 |
| 1.664e-02 | -4.10 | GCAAGAC_MIR431 | MSigDB lists | GCAAGAC_MIR431 | 42 | 8 | 15632 | 1249 |
Map2k4,Nr4a3,Ptpn2,N4bp1,Tmem200b,Pdlim7,Cd34,Kcnj2 |
| 1.665e-02 | -4.10 | organic acid biosynthetic process | biological process | GO:0016053 | 234 | 25 | 20694 | 1406 |
Mthfd1l,Tha1,Lipg,Plod3,Il1b,Kmo,Nr1h3,Dhrs9,Cd74,Plod2,Edn1,Sphk1,Ptges,Asns,Ldha,Psat1,Dse,Gch1,Pla2g4a,Ass1,Asah2,Mthfr,Syk,Ptgs2,Phgdh |
| 1.670e-02 | -4.09 | GSE29949_MICROGLIA_BRAIN_VS_CD8_NEG_DC_SPLEEN_UP | MSigDB lists | GSE29949_MICROGLIA_BRAIN_VS_CD8_NEG_DC_SPLEEN_UP | 170 | 22 | 15632 | 1249 |
St7,Isg15,Arl4a,Upp1,Egr1,Cd200,Ahr,Sdc4,Cd83,Rims3,Tnfsf14,Klhl25,Tnfrsf1b,Ccl5,Fcgr4,Nr4a1,Gadd45g,Met,Hspa2,Usp12,Mmp13,Slc39a14 |
| 1.670e-02 | -4.09 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | 170 | 22 | 15632 | 1249 |
Cd55,F11r,Rcan1,Trib1,Dmxl2,Socs1,Fscn1,Gfpt1,Sdc4,Fam102b,Gfi1,Dach1,Mier3,Txnrd1,Dusp6,Rrs1,Nrp2,Ppp4r2,Stat4,Rnf19a,Spint2,Usp35 |
| 1.670e-02 | -4.09 | GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_DN | MSigDB lists | GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_DN | 170 | 22 | 15632 | 1249 |
Jarid2,Stat5a,Rnf114,Casp1,Cst7,Otud1,Cep350,Zc3h7a,Rffl,Fgl2,Tdrd7,Cers6,Hlx,Ptprj,Il13ra1,Dck,Mppe1,Socs1,Acsl5,Aff1,Tnfrsf14,Igf1r |
| 1.670e-02 | -4.09 | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 170 | 22 | 15632 | 1249 |
Lrp4,Casp1,Ppp1r14b,Dync1h1,Cnn2,Dpy19l1,Serp1,Cd302,Tmem184b,Atf3,Ube2e1,Klf8,Ccnd2,Higd1a,Cnn3,Eef1e1,Slc31a1,Stat1,Zc3h12a,Xkr8,Arid5b,Zcchc2 |
| 1.670e-02 | -4.09 | GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN | 170 | 22 | 15632 | 1249 |
Stau1,Rras2,Prdx1,Aim2,Casp3,Eno1,Bcl6,Gpsm2,Swap70,Ppp1r14b,Snapc1,Ldha,Ppa1,Mtmr14,Trip13,Alas1,Spen,Fubp1,Cd86,Irf8,Lnpep,Pdk3 |
| 1.674e-02 | -4.09 | ACATTCC_MIR1_MIR206 | MSigDB lists | ACATTCC_MIR1_MIR206 | 271 | 32 | 15632 | 1249 |
Gch1,Gja1,Slc7a2,Fosb,Daam1,Phlpp2,Cnn3,Met,Rictor,Mmd,Eya4,Snx2,Fndc3a,Slc25a22,Gpd2,Phf6,Rnf145,Ust,Rsbn1,Tfec,Stard7,Slc37a3,Hivep2,Cited2,Slc44a1,Edn1,Zfp800,Nr1h3,Adar,Slc25a25,Mapkbp1,Spred1 |
| 1.681e-02 | -4.09 | CTTTGCA_MIR527 | MSigDB lists | CTTTGCA_MIR527 | 220 | 27 | 15632 | 1249 |
Chst11,Mafk,Acvr1,Mecp2,Aebp2,Zfp800,Fchsd2,Atp11a,Usp12,Hap1,Rap1gap2,Pde7b,Spen,Rtn2,Mier3,Pmepa1,Rsbn1,Chd9,Phf6,Chic2,Gpr85,Kpna3,Egr3,Cpeb4,Socs3,Fndc3a,Dnaja2 |
| 1.683e-02 | -4.08 | - | gene3d domains | 1.10.101.10 | 7 | 3 | 8819 | 755 |
Mmp9,Mmp13,Mmp14 |
| 1.683e-02 | -4.08 | cellular amino acid metabolic process | biological process | GO:0006520 | 246 | 26 | 20694 | 1406 |
P4ha1,Tha1,Gclm,Plod3,Kmo,Gclc,Txnrd1,Plod2,Wars,Il4i1,Adhfe1,Asns,Psat1,Rars,Ass1,Odc1,Mthfr,Gfpt1,Arg2,Hdc,Ero1l,Mecp2,P4ha2,Nos2,Phgdh,Egln3 |
| 1.683e-02 | -4.08 | respiratory system development | biological process | GO:0060541 | 246 | 26 | 20694 | 1406 |
Spry2,Slc7a11,Jmjd6,Klf2,Foxp4,Errfi1,Gpsm2,Mmp14,Sav1,Hhex,Notch1,Hmga2,Plod3,Sec24b,Rpgrip1l,Pdgfrb,Stk40,Hopx,Pdpn,Lox,Tulp3,Lif,Kdr,Tnc,Map2k1,Timeless |
| 1.684e-02 | -4.08 | GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | MSigDB lists | GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | 180 | 23 | 15632 | 1249 |
Cxcl2,Btg2,Isg20,Plscr1,Phlda1,Cd274,Ppfibp2,Ccl4,Socs3,Fgl2,Micall2,Oaf,Gclm,Dusp2,Gpsm2,Trip10,Armcx6,Crim1,Rgs3,Gbp2,Tnfaip3,Sav1,Tpx2 |
| 1.684e-02 | -4.08 | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_DN | 180 | 23 | 15632 | 1249 |
Cx3cr1,Hsd17b12,Arhgef3,Bcl6,Slc2a1,Edn1,Rai14,Sdc2,Eef1e1,Kctd12,Hp,Magohb,Slc31a1,Egr1,Tgfbi,Sdc1,Clec4d,Slc16a1,Plaur,Trem1,Glrx,Hsd17b7,Htr2b |
| 1.687e-02 | -4.08 | phosphate acquisition II | BIOCYC pathways | MOUSE_PWY-6355 | 17 | 5 | 1025 | 97 |
Kif9,Acpp,Acp2,Prdx1,Acp5 |
| 1.688e-02 | -4.08 | GO_DIOXYGENASE_ACTIVITY | MSigDB lists | GO_DIOXYGENASE_ACTIVITY | 76 | 12 | 15632 | 1249 |
Jmjd6,Phyh,Ptgs2,Kdm4a,Kdm6b,Egln3,Kdm5b,Plod2,Tet2,Plod3,P4ha1,P4ha2 |
| 1.688e-02 | -4.08 | SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP | MSigDB lists | SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP | 76 | 12 | 15632 | 1249 |
Apaf1,Hat1,Myc,Hif1a,Itpr1,Tlr2,Casp4,Txn1,Ccr1,Nck1,Casp1,Sod2 |
| 1.688e-02 | -4.08 | PID_MYC_ACTIV_PATHWAY | MSigDB lists | PID_MYC_ACTIV_PATHWAY | 76 | 12 | 15632 | 1249 |
Ldha,Mmp9,Mtdh,Max,Odc1,Ccnd2,Pim1,Eno1,Slc2a1,Hmga1,Myc,Taf4b |
| 1.688e-02 | -4.08 | KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY | MSigDB lists | KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY | 76 | 12 | 15632 | 1249 |
Pik3cd,Lyn,Map2k4,Rac3,Map2k1,Lcp2,Syk,Pik3r5,Tnf,Prkce,Pla2g4a,Akt3 |
| 1.689e-02 | -4.08 | CD28 dependent PI3K/Akt signaling | REACTOME pathways | R-MMU-389357 | 18 | 5 | 8608 | 757 |
Rictor,Cd86,Map3k8,Cd80,Trib3 |
| 1.689e-02 | -4.08 | MODULE_146 | MSigDB lists | MODULE_146 | 94 | 14 | 15632 | 1249 |
Cx3cr1,Ccr1,Ednrb,Ccr3,Ccl2,S1pr2,Adora2a,Lpar1,Calcrl,Fpr2,Fpr1,P2ry14,Adrb2,Htr2b |
| 1.690e-02 | -4.08 | mouse chr10|10 A2 | chromosome location | mouse chr10|10 A2 | 17 | 4 | 24173 | 1464 |
Adgrg6,Cited2,Hivep2,Stx11 |
| 1.691e-02 | -4.08 | CHANG_CORE_SERUM_RESPONSE_UP | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_UP | 190 | 24 | 15632 | 1249 |
Pdlim7,Met,Tuba4a,Junb,Cenpj,Plod2,Plaur,Dcbld2,Dck,Cpeb4,Map3k8,Cox17,Spryd7,Tagln,Srm,Ezr,Eno1,Slc16a1,Gng11,Rhoc,Tpi1,Magohb,Sdc1,Pgm1 |
| 1.691e-02 | -4.08 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_DN | 190 | 24 | 15632 | 1249 |
Sdc4,Clic4,Phyh,Ptgs2,Plagl1,Acsl1,Marcksl1,Egr1,Filip1l,Cd200,Slc39a14,Fut8,Pla2g4a,Timeless,Rab11fip1,Slc7a5,Stap1,Gna15,Lap3,Eno1,Med21,Hsd17b12,Txnrd1,Trmt1l |
| 1.691e-02 | -4.08 | GO_RESPIRATORY_SYSTEM_DEVELOPMENT | MSigDB lists | GO_RESPIRATORY_SYSTEM_DEVELOPMENT | 190 | 24 | 15632 | 1249 |
Lox,Rpgrip1l,Sec24b,Klf2,Hopx,Map2k1,Timeless,Fzd1,Hhex,Lif,Tulp3,Jmjd6,Sav1,Notch1,Plod3,Ass1,Gpsm2,Tnc,Spry2,Mmp14,Cp,Pdpn,Errfi1,Stk40 |
| 1.691e-02 | -4.08 | GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_DN | 190 | 24 | 15632 | 1249 |
Dhx58,Parp9,Psma6,Il18bp,Glipr2,Arhgap26,Hdac1,Rnf114,Zbp1,Pilra,Tap1,Gbp2,Ifit1,Lrp8,Usp18,Uba7,Casp4,Mov10,Ust,Parp3,Ifi35,Map3k8,Spata5l1,Rcn1 |
| 1.691e-02 | -4.08 | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN | 190 | 24 | 15632 | 1249 |
Ripk2,Irak2,Zcchc2,Sh3bgrl2,Rsbn1,Zhx2,Eif4g2,Arid4a,Klf2,Pstpip2,Rhoh,Znrf3,Kat2b,Sdc4,Nod1,Slc28a2,Pik3r5,Hspa1a,Prkce,Itgb8,Ccr3,Sat1,Rin2,Phlpp1 |
| 1.691e-02 | -4.08 | embryonic placenta development | biological process | GO:0001892 | 110 | 14 | 20694 | 1406 |
Map2k1,Il10,Fzd5,Junb,Itga4,Prdm1,Itgav,Spint2,Vcam1,Hif1a,Socs3,Pdgfb,Cited2,Lif |
| 1.692e-02 | -4.08 | GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_2H_DN | MSigDB lists | GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_2H_DN | 141 | 19 | 15632 | 1249 |
Znrf1,Clcf1,Bambi,Nfil3,Cd55,Evl,Trim13,Gbe1,Jmjd6,Mdn1,Btg2,Fchsd2,Taf4b,Maff,Parp8,Gpr18,Higd1a,Klf2,Irf7 |
| 1.692e-02 | -4.08 | GO_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | 141 | 19 | 15632 | 1249 |
Cxcl10,Il4ra,Il18,Notch1,Daxx,Bmp2,Cflar,Ankrd17,Hopx,Tnfsf14,Gdf15,Ehd1,Tnf,Cxcl14,Hdac1,Mmp14,Pdgfb,Edn1,Zeb1 |
| 1.694e-02 | -4.08 | ubiquitin-like protein-specific protease activity | molecular function | GO:0019783 | 108 | 14 | 20217 | 1400 |
Uchl1,Usp42,Usp12,Zc3h12a,Usp35,Zup1,Otud1,Tank,Usp31,Usp25,Usp18,Vcpip1,Usp53,Tnfaip3 |
| 1.694e-02 | -4.08 | regulation of cellular amide metabolic process | biological process | GO:0034248 | 379 | 37 | 20694 | 1406 |
Il6,Cyfip1,Mov10,Plekhn1,Ptafr,Tnf,Eif2ak2,Thbs1,Nck1,Cpeb4,Gtpbp2,Klhl25,Prnp,Fam129a,Serp1,Stat3,Hap1,Pml,Ago3,Ppp1r15b,Pdk3,Eif4g2,Sphk1,Larp1,Igf2bp2,Casp3,Xrn1,Gsap,Slc7a11,Nod2,Ythdf1,Btg2,Zc3h12a,Ppp1r15a,Rnf139,Zfp36,Polr2g |
| 1.694e-02 | -4.08 | GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION | MSigDB lists | GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION | 408 | 45 | 15632 | 1249 |
Il6,Eif2ak2,Psmd10,Adar,Nck1,Mapkapk2,Dcp2,Xrn1,Zfp36,Psme2,Dcp1a,Tdrd7,Eif4g2,Psmb8,Ppp1r15b,Tnfrsf1b,Mov10,Cav1,Polr2g,Cpeb4,Stat3,Carhsp1,Ythdf1,Psma6,Tnf,Psmb9,Klhl25,Serp1,Myd88,Psme1,Rnf139,Pml,Psmb10,Btg2,Hap1,Ccl5,Ppp1r15a,Thbs1,Gcnt2,Dio2,Igf2bp2,Larp1,Zc3h12a,Psmb6,Ptafr |
| 1.699e-02 | -4.08 | positive regulation of cell projection organization | biological process | GO:0031346 | 466 | 44 | 20694 | 1406 |
Lpar1,Mul1,Cflar,Il6,Scn1b,Cyfip1,Lif,Lcn2,Hap1,Eif4g2,Map2k1,Rapgef2,Nr3c1,Cdc42ep2,Src,Lyn,Dbnl,Sphk1,Itpr1,Scarf1,Sirt1,P2ry12,Fzd1,Ehd1,Cx3cl1,P2ry2,Mecp2,Kif3c,Cenpj,Rab21,Nck1,Met,Cdc42ep4,Carmil1,Kat2b,Lrp8,D16Ertd472e,Nlgn2,Igf1r,Rhoq,Tmem67,Mark2,Agrn,Fscn1 |
| 1.700e-02 | -4.07 | GO_TISSUE_MORPHOGENESIS | MSigDB lists | GO_TISSUE_MORPHOGENESIS | 516 | 55 | 15632 | 1249 |
Hhex,Pml,Tulp3,Hif1a,Intu,Pbx1,Bmp2,Apaf1,Notch1,Rhoc,Src,Txnrd1,Plod3,Tnc,Setdb2,Mdm2,Kdm5b,Acvr1,Acvrl1,Kdm6b,Nr4a3,Prkx,Clic4,Vegfc,Sec24b,Mthfd1l,Gja1,Fzd5,Rab10,Inhba,Fzd1,Vasp,Sdc4,Ezr,Flrt3,Edn1,Spry2,Myc,Il6,Mmp14,Ift57,Phactr4,Sema4c,Socs3,Itga5,Rpgrip1l,Lhx2,Il10,Sema3c,Lmo4,Ptch1,Csf1,Timeless,Jag1,Met |
| 1.700e-02 | -4.07 | SMITH_TERT_TARGETS_DN | MSigDB lists | SMITH_TERT_TARGETS_DN | 85 | 13 | 15632 | 1249 |
Sp110,Il1rn,Tnfsf10,Idi1,Abr,Pml,Stat4,Hspa2,Pnp2,Fosb,Tcf4,Tagln,Dusp6 |
| 1.700e-02 | -4.07 | KEGG_ERBB_SIGNALING_PATHWAY | MSigDB lists | KEGG_ERBB_SIGNALING_PATHWAY | 85 | 13 | 15632 | 1249 |
Myc,Akt3,Pik3r5,Src,Stat5a,Map2k1,Jun,Cdkn1a,Ptk2,Nck1,Crkl,Map2k4,Pik3cd |
| 1.700e-02 | -4.07 | MODULE_261 | MSigDB lists | MODULE_261 | 85 | 13 | 15632 | 1249 |
Bnip3,Peli1,Nfkbid,G3bp2,Syne2,Cd69,Crkl,Usp25,Slc25a22,Irs2,Orai2,Tagap,Cd164 |
| 1.700e-02 | -4.07 | KAYO_CALORIE_RESTRICTION_MUSCLE_UP | MSigDB lists | KAYO_CALORIE_RESTRICTION_MUSCLE_UP | 85 | 13 | 15632 | 1249 |
Actb,Plau,Hcls1,Fas,Ier2,Upp1,Nr4a3,Cnn3,Itgb8,Ccl2,Bcl6,Cd302,Tank |
| 1.701e-02 | -4.07 | regulation of T cell receptor signaling pathway | biological process | GO:0050856 | 40 | 7 | 20694 | 1406 |
Usp12,Ptpn2,Prnp,Malt1,Nectin2,Ptprj,Ezr |
| 1.702e-02 | -4.07 | GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP | MSigDB lists | GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP | 122 | 17 | 15632 | 1249 |
Kcnj2,Stat4,Kdm5b,Zswim4,Card6,Ppm1k,Extl2,Rras2,Fam102b,Inpp1,Rbm43,Cd164,Crim1,Frmd6,Tlr6,Usp18,Nsmaf |
| 1.702e-02 | -4.07 | GO_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 122 | 17 | 15632 | 1249 |
Mdm2,Rnf19a,Rnf24,Rffl,Ubr4,Klhl25,Ankib1,Rnf14,Keap1,Herc3,Bfar,Rnf34,Rnf145,Pttg1,Herc6,Ube2e1,Rnf19b |
| 1.702e-02 | -4.07 | GSE45365_NK_CELL_VS_BCELL_DN | MSigDB lists | GSE45365_NK_CELL_VS_BCELL_DN | 122 | 17 | 15632 | 1249 |
Angpt1,Gclc,Pde3b,Rgs1,Calcrl,Rab19,Il2rg,Traf1,Stat4,Treml2,Ube2e2,Ccrl2,Gsr,Cysltr2,Pla2g4a,Ddit4,Arl5b |
| 1.703e-02 | -4.07 | Asthma | KEGG pathways | ko05310 | 24 | 6 | 7931 | 713 |
H2-Ab1,H2-Aa,H2-Eb1,Cd40,Il10,Tnf |
| 1.703e-02 | -4.07 | Asthma | KEGG pathways | mmu05310 | 24 | 6 | 7931 | 713 |
Il10,H2-Aa,Tnf,Cd40,H2-Eb1,H2-Ab1 |
| 1.705e-02 | -4.07 | SAND | smart domains | SM00258 | 7 | 3 | 9567 | 823 |
Sp140,Sp100,Sp110 |
| 1.705e-02 | -4.07 | GS | smart domains | SM00467 | 7 | 3 | 9567 | 823 |
Acvr1,Acvrl1,Acvr1b |
| 1.705e-02 | -4.07 | IRF-3 | smart domains | SM01243 | 7 | 3 | 9567 | 823 |
Irf8,Irf4,Irf7 |
| 1.706e-02 | -4.07 | regulation of ATP metabolic process | biological process | GO:1903578 | 89 | 12 | 20694 | 1406 |
Pid1,Ddit4,Map2k1,Myc,Htr2a,Ier3,Stat3,Tspo,Pgk1,Nupr1,Ak4,Hif1a |
| 1.710e-02 | -4.07 | Regulation of actin dynamics for phagocytic cup formation | REACTOME pathways | R-MMU-2029482 | 46 | 9 | 8608 | 757 |
Syk,Fcgr4,Myo10,Fcgr2b,Nck1,Actb,Fcgr1,Cyfip1,Ptk2 |
| 1.717e-02 | -4.06 | regulation of mRNA catabolic process | biological process | GO:0061013 | 121 | 15 | 20694 | 1406 |
Myd88,Noct,Zfp36,Zc3h12a,Carhsp1,Dcp2,Btg2,Polr2g,Mapkapk2,Zc3hav1,Plekhn1,Larp1,Mov10,Tent4a,Pnpt1 |
| 1.722e-02 | -4.06 | GO_DEPHOSPHORYLATION | MSigDB lists | GO_DEPHOSPHORYLATION | 251 | 30 | 15632 | 1249 |
Acpp,Ptpn2,Dusp1,Phlpp1,Dusp4,Cycs,Minpp1,Dusp2,Dusp8,Ubash3b,Ppm1l,Nck1,Dusp14,Pfkfb3,Ppp1r15a,Ppm1k,Dusp6,Ppp1r15b,Eya4,Ppp2r3a,Inpp5b,Phlpp2,Mtmr14,Ptprj,Dusp5,Dusp16,Dusp28,Acp2,Ppp2r2a,Inpp1 |
| 1.729e-02 | -4.06 | cellular response to pH | biological process | GO:0071467 | 23 | 5 | 20694 | 1406 |
Hvcn1,Slc9a1,Gpr68,Gja1,Nox1 |
| 1.729e-02 | -4.06 | negative regulation of phagocytosis | biological process | GO:0050765 | 23 | 5 | 20694 | 1406 |
Fcgr2b,Tlr2,Cnn2,Cd300lf,Siglece |
| 1.729e-02 | -4.06 | negative regulation of leukocyte mediated cytotoxicity | biological process | GO:0001911 | 23 | 5 | 20694 | 1406 |
Tap1,Tap2,Clec2d,Serpinb9,Lgals9 |
| 1.729e-02 | -4.06 | cellular response to monoamine stimulus | biological process | GO:0071868 | 23 | 5 | 20694 | 1406 |
Pde4b,Slc9a1,Atp2b4,Htr2b,Nr4a3 |
| 1.729e-02 | -4.06 | regulation of cholesterol efflux | biological process | GO:0010874 | 23 | 5 | 20694 | 1406 |
Ttc39b,Nfkbia,Ptch1,Sirt1,Nr1h3 |
| 1.729e-02 | -4.06 | ruffle organization | biological process | GO:0031529 | 23 | 5 | 20694 | 1406 |
Snx10,Dbnl,Carmil1,Palld,Plek |
| 1.729e-02 | -4.06 | diol metabolic process | biological process | GO:0034311 | 23 | 5 | 20694 | 1406 |
Degs2,Sphk1,Plpp1,Gch1,Asah2 |
| 1.730e-02 | -4.06 | GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN | 151 | 20 | 15632 | 1249 |
Plekha5,Plac8,Map2k1,Cyfip1,Cd274,Zc3h12c,Ctsc,Nrp2,Dock10,Ube2e2,Prdm9,Tlr3,Ptprj,Abr,Rnf145,Cd300lf,Herc3,Hck,Cd38,Dusp16 |
| 1.731e-02 | -4.06 | head development | biological process | GO:0060322 | 670 | 60 | 20694 | 1406 |
Igf1r,Socs7,D16Ertd472e,Sema4c,Tsku,Ext1,Csrnp1,Stxbp3,Irs2,Lrp8,Fabp7,Arid5b,Rpgrip1l,Itga4,Sec24b,Slc4a7,Mmp14,Pou3f1,Kdm6b,Rac3,Tulp3,Mecp2,Egr2,P2ry12,Apaf1,Hdac1,Ikzf1,Met,Cx3cr1,Fcgr2b,Ddit4,Crkl,Sphk1,Ptch1,Flrt3,Slc7a11,Inhba,Nr4a3,Cdk5r1,Btg2,Tiparp,Axl,Akt3,Hmga2,Hhex,Notch1,Tal2,Atm,Hif1a,Abr,Syne2,B3gnt5,Nrp2,Rapgef2,Lhx2,Src,Hap1,Adgrl2,Map2k1,Bmp2 |
| 1.733e-02 | -4.06 | KBD | prosite domains | PS51488 | 3 | 2 | 13278 | 1037 |
Spred3,Spred1 |
| 1.733e-02 | -4.06 | HTH_OST | prosite domains | PS51644 | 3 | 2 | 13278 | 1037 |
Tdrd7,Marf1 |
| 1.733e-02 | -4.06 | ZF_CCHC_NOA | prosite domains | PS51801 | 3 | 2 | 13278 | 1037 |
Ikbkg,Optn |
| 1.733e-02 | -4.06 | LYS_HYDROXYLASE | prosite domains | PS01325 | 3 | 2 | 13278 | 1037 |
Plod2,Plod3 |
| 1.733e-02 | -4.06 | HIS_ACID_PHOSPHAT_2 | prosite domains | PS00778 | 3 | 2 | 13278 | 1037 |
Acp2,Acpp |
| 1.733e-02 | -4.06 | G_VLIG | prosite domains | PS51717 | 3 | 2 | 13278 | 1037 |
Gm4070,Gvin1 |
| 1.743e-02 | -4.05 | negative regulation of muscle cell differentiation | biological process | GO:0051148 | 59 | 9 | 20694 | 1406 |
Bmp2,Notch1,Daxx,Cflar,Cxcl10,Tomm70a,Ankrd17,Mecp2,Pdgfb |
| 1.743e-02 | -4.05 | nucleoside diphosphate phosphorylation | biological process | GO:0006165 | 59 | 9 | 20694 | 1406 |
Ak4,Pfkl,Hk2,Hk3,Eno2,Tpi1,Cmpk2,Pgk1,Hk1 |
| 1.743e-02 | -4.05 | positive regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001238 | 59 | 9 | 20694 | 1406 |
Casp8,Pml,Cav1,Atf3,Inhba,Tnfsf10,Traf2,Ppp2r1b,Thbs1 |
| 1.752e-02 | -4.04 | cell adhesion | biological process | GO:0007155 | 787 | 69 | 20694 | 1406 |
Cd200,Prkce,Cdk5r1,Sell,Tnip1,Slc7a11,F11r,Flrt3,Itgav,Il1b,Scarf1,Lgals9,Sele,Cd164,Axl,Itgal,Itga9,Palld,Olr1,Vcan,Itga5,Dst,Pvr,Micall2,Tgfbi,Whamm,Src,Plek,Bcl2l11,Pcdh7,Thbs1,Spn,Cd34,Pkp4,Ccl5,Icam1,Col18a1,Igsf9,Flrt2,Stxbp3,Ntng2,Csf3r,Vcam1,Nlgn2,Antxr1,Fndc3a,Prkx,Itgb8,Nectin2,Nectin4,Itga4,Tnf,Pdpn,Cx3cl1,P2ry12,Kitl,Stxbp1,Klra2,Tnc,Plpp3,Ubash3b,Syk,Acvr1,Vezt,Zyx,Cx3cr1,Siglece,S100a8,Angpt1 |
| 1.756e-02 | -4.04 | mouse chr4|4 B1 | chromosome location | mouse chr4|4 B1 | 66 | 9 | 24173 | 1464 |
Glipr2,Tdrd7,Nr4a3,Aldh1b1,Trim14,Zbtb5,Msantd3,Tmeff1,Stra6l |
| 1.758e-02 | -4.04 | GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 161 | 21 | 15632 | 1249 |
Insl6,Plek,Snx10,Cx3cr1,Fcgr2b,Spry2,Rap1gap2,Il18rap,Smpdl3b,Fgl2,Dusp5,Casp7,Prdm1,Adrb2,Map3k8,Tpx2,Slc43a3,Slc48a1,Ccl4,Cmklr1,Dusp16 |
| 1.758e-02 | -4.04 | GSE12366_GC_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE12366_GC_BCELL_VS_PLASMA_CELL_DN | 161 | 21 | 15632 | 1249 |
Ell2,Socs3,Stat1,Cd55,Mtdh,Psme1,Cd38,Sec24a,Pde3b,Osbpl3,Sgk3,Nfxl1,Cflar,Mgat1,Tmem184b,Irf7,Casp1,Smpdl3b,Ccrl2,Btg2,Bcl9 |
| 1.758e-02 | -4.04 | GO_BINDING_BRIDGING | MSigDB lists | GO_BINDING_BRIDGING | 161 | 21 | 15632 | 1249 |
Bfar,Fscn1,Sla,Crkl,Nck1,Frmd4a,Trim12c,Mpp7,Ksr1,Slc9a1,Ppp4r2,Stap1,Optn,Ppp2r3a,Src,Flrt3,Homer1,Flrt2,Cav1,Col11a2,Adap2 |
| 1.759e-02 | -4.04 | GO_CYTOPLASMIC_MRNA_PROCESSING_BODY | MSigDB lists | GO_CYTOPLASMIC_MRNA_PROCESSING_BODY | 59 | 10 | 15632 | 1249 |
Psma6,Dcp1a,Polr2g,Trim21,Carhsp1,Mov10,Dcp2,Trim12c,Sqstm1,Zc3h12a |
| 1.759e-02 | -4.04 | TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_UP | MSigDB lists | TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_UP | 59 | 10 | 15632 | 1249 |
Pmepa1,Maff,Col27a1,Spata5l1,Fosb,St3gal6,Cx3cl1,Lrch3,Atf3,Usp25 |
| 1.760e-02 | -4.04 | ONDER_CDH1_TARGETS_2_UP | MSigDB lists | ONDER_CDH1_TARGETS_2_UP | 231 | 28 | 15632 | 1249 |
Kat2b,Nupr1,Olfml3,Gng11,Cited2,Dock4,Tagln,Gypc,Gadd45b,Dusp1,Dock10,Vcan,Sdc2,Lox,Arid5b,Dnajb4,Lpar1,Hmox1,Ptger4,Glrx,Plod2,Slc7a2,Serpine1,Pid1,Ltbp2,Rgl1,Eno2,Zeb1 |
| 1.760e-02 | -4.04 | NLRC_HD2 | interpro domains | IPR041267 | 22 | 5 | 19984 | 1430 |
Ciita,Nod2,Nlrc5,Nod1,Nlrp3 |
| 1.764e-02 | -4.04 | AACATTC_MIR4093P | MSigDB lists | AACATTC_MIR4093P | 132 | 18 | 15632 | 1249 |
Gpd2,Osgin2,Phf6,Tfec,Ust,Fosb,Rhof,Jun,Cited2,Gja1,Pde4b,Hivep2,Met,Kctd12,Eya4,Mmd,Zfp800,Edn1 |
| 1.767e-02 | -4.04 | positive regulation of fibroblast proliferation | biological process | GO:0048146 | 69 | 10 | 20694 | 1406 |
Pml,Cd74,Serpine1,Jun,Cdkn1a,Pdgfrb,Pdgfc,Pdgfb,Myc,Sphk1 |
| 1.772e-02 | -4.03 | MODULE_210 | MSigDB lists | MODULE_210 | 27 | 6 | 15632 | 1249 |
Mmp14,Mmp13,Mmp9,Traf2,Timp1,Traf1 |
| 1.772e-02 | -4.03 | MCBRYAN_PUBERTAL_BREAST_3_4WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_3_4WK_DN | 27 | 6 | 15632 | 1249 |
Nfkb2,Alas1,Cdkn1a,Hp,Bcl6,Fabp3 |
| 1.772e-02 | -4.03 | GO_NEGATIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS | 27 | 6 | 15632 | 1249 |
Errfi1,Inhba,Nmi,Il6,Il10,Nfkb1 |
| 1.772e-02 | -4.03 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | MSigDB lists | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | 27 | 6 | 15632 | 1249 |
Cycs,Casp3,Apaf1,Casp7,Bcl2l11,Casp8 |
| 1.772e-02 | -4.03 | TAVOR_CEBPA_TARGETS_DN | MSigDB lists | TAVOR_CEBPA_TARGETS_DN | 27 | 6 | 15632 | 1249 |
Tnfsf10,Gja1,Myc,Oas2,Isg15,Plod2 |
| 1.772e-02 | -4.03 | GO_RESPONSE_TO_GROWTH_HORMONE | MSigDB lists | GO_RESPONSE_TO_GROWTH_HORMONE | 27 | 6 | 15632 | 1249 |
Jak2,Stat3,Stat5a,Ptk2,Ass1,Lyn |
| 1.772e-02 | -4.03 | GO_LEUKOCYTE_DEGRANULATION | MSigDB lists | GO_LEUKOCYTE_DEGRANULATION | 27 | 6 | 15632 | 1249 |
Nr4a3,Lyn,Pik3cd,Hck,Rasgrp1,Stxbp3 |
| 1.772e-02 | -4.03 | GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | 27 | 6 | 15632 | 1249 |
Kdr,Tnfaip3,Serpine1,Angpt1,Il10,Icam1 |
| 1.772e-02 | -4.03 | GO_ACTIVATION_OF_PHOSPHOLIPASE_C_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_PHOSPHOLIPASE_C_ACTIVITY | 27 | 6 | 15632 | 1249 |
Gna15,Lpar1,Prkce,Htr2a,Sele,Htr2b |
| 1.772e-02 | -4.03 | GO_REGULATION_OF_ASTROCYTE_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_ASTROCYTE_DIFFERENTIATION | 27 | 6 | 15632 | 1249 |
Il1b,Mecp2,Notch1,Bmp2,Lif,Clcf1 |
| 1.772e-02 | -4.03 | HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_DN | MSigDB lists | HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_DN | 27 | 6 | 15632 | 1249 |
Stip1,Ccnd1,Ier3,Dusp14,Gdf15,Txnrd1 |
| 1.777e-02 | -4.03 | GO_PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | GO_PROTEIN_TYROSINE_KINASE_ACTIVITY | 171 | 22 | 15632 | 1249 |
Stat5a,Src,Axl,Flt1,Eif2ak2,Syk,Crim1,Hck,Fgr,Met,Tyk2,Nrp2,Pdgfrb,Map2k1,Igf1r,Jak2,Kdr,Map2k4,Lyn,Ptk2,Dyrk2,Ripk2 |
| 1.777e-02 | -4.03 | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_DN | 171 | 22 | 15632 | 1249 |
H2-Q7,Itga4,Zc3hav1,Cutc,Rnd3,D16Ertd472e,H2-Q6,Sp140,H2-Q4,Tra2a,Tlk2,Arid5b,Cd200,Dyrk2,Sema4c,Ptch1,Sik3,Klf2,Pde4b,Oas2,Zeb1,Akt3 |
| 1.777e-02 | -4.03 | GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 171 | 22 | 15632 | 1249 |
Dnajb2,Keap1,Gclc,Trib3,Trib1,Plk3,Psme1,Rnf19b,Smc5,Mdm2,Tlk2,Rnf19a,Psme2,Cav1,Plk2,Psmd10,Ankib1,Dusp1,Atm,Rnf14,N4bp1,Rnf114 |
| 1.777e-02 | -4.03 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP | 171 | 22 | 15632 | 1249 |
Mfap3l,Tap2,Higd1a,Serp1,Lap3,Pstpip2,Reps1,Rab9,Mmd,Xaf1,Psma6,Endod1,Psme1,H2-Ab1,C3,Ptgir,Il1a,Cflar,Tax1bp1,Gng11,Pf4,Prkar2b |
| 1.777e-02 | -4.03 | HEN1_02 | MSigDB lists | HEN1_02 | 171 | 22 | 15632 | 1249 |
Pdgfb,Jag1,Abtb2,Eif4g2,Daam1,Nr4a3,Stat3,Myc,Slc44a1,Atp13a1,Parp8,Phldb1,Tcf4,Mgat1,Dock4,Etv5,Plagl2,Psme1,Zfp513,Klf8,F11r,Arl4a |
| 1.777e-02 | -4.03 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_DN | 171 | 22 | 15632 | 1249 |
Ccl4,Clcn7,Lpar1,Syne2,Ccdc25,Btg2,Fosb,Ubr4,Ppfibp1,Pdgfc,Apaf1,Sla,Ciita,Cdk5r1,Egr1,Ier2,Atp13a1,Katna1,Il6,Jun,Dusp1,Cenpe |
| 1.779e-02 | -4.03 | GO_PROTEIN_DOMAIN_SPECIFIC_BINDING | MSigDB lists | GO_PROTEIN_DOMAIN_SPECIFIC_BINDING | 583 | 61 | 15632 | 1249 |
Hspa1a,Src,Mecp2,Mafk,Errfi1,Fut8,Dbnl,Egr2,Rhoq,F11r,Hhex,Apba1,Crim1,Myd88,Nod1,Gja1,Rapgef2,Vasp,Fzd1,Reps1,Ripk2,Gng12,Plaur,Il1b,Mitd1,Cited2,Jun,Dnaja1,Dock4,Ezr,Sqstm1,Sdc2,Nod2,Pttg1,Irs2,Mpp7,Evl,Nck1,Stxbp1,Atp2b4,Plekha2,Casp8,Cenpj,Ikbkg,Sirt1,Etv6,Casp2,Pou2f2,Plscr1,Aida,Lpar1,Lyn,Ptk2,Vrk2,Socs7,Prkar2b,Pmepa1,Jak2,Sh3bgrl2,Adam19,Hcls1 |
| 1.784e-02 | -4.03 | Glycolysis, core module involving three-carbon compounds | KEGG pathways | mmu_M00002 | 12 | 4 | 7931 | 713 |
Pgk1,Tpi1,Eno2,Eno1 |
| 1.784e-02 | -4.03 | ECS complex | KEGG pathways | mmu_M00388 | 12 | 4 | 7931 | 713 |
Socs3,Socs7,Cish,Socs1 |
| 1.784e-02 | -4.03 | Glycolysis, core module involving three-carbon compounds | KEGG pathways | M00002 | 12 | 4 | 7931 | 713 |
Pgk1,Tpi1,Eno2,Eno1 |
| 1.784e-02 | -4.03 | ECS complex | KEGG pathways | M00388 | 12 | 4 | 7931 | 713 |
Socs3,Socs7,Cish,Socs1 |
| 1.788e-02 | -4.02 | TPR_repeat | interpro domains | IPR019734 | 126 | 16 | 19984 | 1430 |
P4ha2,Stip1,Zc3h7a,Ttc9c,Gpsm2,Ifit2,Ifit3b,Tmtc2,Ifit1bl1,Ifit1,Ifit1bl2,Ttc39b,P4ha1,Ifit3,Ranbp2,Tomm70a |
| 1.788e-02 | -4.02 | GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 181 | 23 | 15632 | 1249 |
Slfn9,Snn,Traf3ip2,Parp3,H2-Aa,Pde4b,Cnp,Ppp1r15a,Adap2,Plekha2,Igsf8,Irf7,Cd38,Itga4,Evl,Rtp4,Slfn8,Rhoq,Slc15a3,Mafk,Bcl2l11,Mgat1,Zyx |
| 1.788e-02 | -4.02 | GSE11924_TH1_VS_TH17_CD4_TCELL_DN | MSigDB lists | GSE11924_TH1_VS_TH17_CD4_TCELL_DN | 181 | 23 | 15632 | 1249 |
Slc25a12,Tmem26,Cysltr2,Ext1,Pstpip2,Slc2a6,Stxbp3,Map4k4,Ahrr,Lacc1,Tmem219,Sec24a,Bambi,Arid5b,Aebp2,Ccr3,Setdb2,Hck,Extl2,Hinfp,Upp1,Slco3a1,Gbe1 |
| 1.788e-02 | -4.02 | GSE3982_NKCELL_VS_TH2_DN | MSigDB lists | GSE3982_NKCELL_VS_TH2_DN | 181 | 23 | 15632 | 1249 |
Tnfrsf8,Tsku,Pttg1,Icam1,Irgq,Pla2g4a,Ggct,Dusp4,Mdm2,Ezr,Rbbp8,Clic4,Esd,Psmb6,Filip1l,Cd200,Ptgs2,Phyh,Slc7a5,Hk2,Slc39a14,Hivep3,Osm |
| 1.788e-02 | -4.02 | GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP | MSigDB lists | GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP | 181 | 23 | 15632 | 1249 |
Lrrc8c,5430427O19Rik,Prdm9,Parp11,Tmem229b,Grina,Rapgef2,Dcp1a,Card6,Ppp1r15b,Tor1aip1,Itgal,Hinfp,Samhd1,Atp11b,Parp14,Abcb1a,Cept1,Cd200r4,Dock10,Morc3,Spn,Psmb9 |
| 1.788e-02 | -4.02 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 181 | 23 | 15632 | 1249 |
Pim1,Upp1,Endod1,Psme1,Mvp,Inpp1,Bcl2a1a,Nod1,C1rl,Klf2,Asns,Bcl2a1b,Dhrs9,Sqstm1,Dusp1,Klf3,Klf6,Pde4b,Rap1gap2,Bcl2a1d,Stat4,Csf3,Ly75 |
| 1.788e-02 | -4.02 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP | 181 | 23 | 15632 | 1249 |
Sgcb,Aff1,Ncoa7,Pml,Acvrl1,Lztfl1,Ttc39c,Tnfaip2,Ppp2r2a,Ppfibp2,Fam162a,Rnaset2b,Itga5,Larp1,Gpd2,Trib1,Pdlim7,Htra1,Met,Slc4a7,Ccr1,Slc7a8,Rnaset2a |
| 1.788e-02 | -4.02 | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN | 181 | 23 | 15632 | 1249 |
Tap2,Irf7,Tor3a,Psmb8,St3gal5,Odc1,Rnf145,Kif3c,Larp1,Xcr1,Kitl,Cnn2,Bcl2l11,Srm,Ppp1r14b,Mdm2,Tapbp,Ly75,Dbnl,Pml,Tpi1,Nek6,Tap1 |
| 1.793e-02 | -4.02 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN | 191 | 24 | 15632 | 1249 |
Abcc5,Ezr,Gbp9,Gbp4,Nr3c1,Traf1,Lipg,Rras2,Tle3,Notch1,Crim1,Cd164,Il10,Gpr132,Syne2,Hivep3,Stat1,Adrb2,Nr4a3,Rab20,Sh3bgrl2,Gfi1,Ap3m2,Pmepa1 |
| 1.793e-02 | -4.02 | GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_DN | MSigDB lists | GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_DN | 191 | 24 | 15632 | 1249 |
Tnfsf14,Lcp2,Myo1b,Ccne1,Wars,Eef1e1,Ldha,Ptgir,Fscn1,Il1rn,Bcl2a1a,Eno1,Trip10,Bcl2a1b,Cst7,Psma6,Bcl2a1d,Dusp4,Gclm,Phgdh,Ggct,Tpx2,Traf1,Prdx1 |
| 1.805e-02 | -4.01 | GO_PROTEASE_BINDING | MSigDB lists | GO_PROTEASE_BINDING | 104 | 15 | 15632 | 1249 |
Casp3,Rffl,Timp1,Serpine1,Tnf,Itgav,Tnfaip3,Bfar,Cflar,Ldlr,Sell,Serpinb9,Malt1,Fas,Rnf139 |
| 1.808e-02 | -4.01 | NLRC4_HD2 | pfam domains | PF17776 | 22 | 5 | 18711 | 1348 |
Nod2,Nlrp3,Ciita,Nod1,Nlrc5 |
| 1.812e-02 | -4.01 | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_FOXP3_TRASDUCED_CD4_TCELL_DN | MSigDB lists | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_FOXP3_TRASDUCED_CD4_TCELL_DN | 142 | 19 | 15632 | 1249 |
Ptgs2,Fam53c,Malt1,Hmox1,Tmem219,Nlgn2,Tap1,Prdx1,Nfxl1,Plau,Chd9,Znfx1,Gja1,Dhrs9,Rin2,Stx11,Sap30,Casp3,Piezo1 |
| 1.812e-02 | -4.01 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_14 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_14 | 3 | 2 | 15632 | 1249 |
Myc,Ext1 |
| 1.815e-02 | -4.01 | Endocrine resistance | KEGG pathways | mmu01522 | 93 | 15 | 7931 | 713 |
Igf1r,Mdm2,Fos,Src,Ptk2,Akt3,Jun,Ccnd1,Mmp9,Notch2,Cdkn1a,Map2k1,Pik3cd,Jag1,Notch1 |
| 1.815e-02 | -4.01 | Endocrine resistance | KEGG pathways | ko01522 | 93 | 15 | 7931 | 713 |
Cdkn1a,Jag1,Pik3cd,Map2k1,Notch1,Ccnd1,Mmp9,Notch2,Jun,Igf1r,Ptk2,Akt3,Mdm2,Src,Fos |
| 1.818e-02 | -4.01 | SCHURINGA_STAT5A_TARGETS_UP | MSigDB lists | SCHURINGA_STAT5A_TARGETS_UP | 20 | 5 | 15632 | 1249 |
Pim1,Fosb,Cish,Rac3,Lif |
| 1.818e-02 | -4.01 | GO_FIBRINOLYSIS | MSigDB lists | GO_FIBRINOLYSIS | 20 | 5 | 15632 | 1249 |
Serpine1,Plaur,Serpinb2,Plat,Plau |
| 1.818e-02 | -4.01 | MODULE_186 | MSigDB lists | MODULE_186 | 20 | 5 | 15632 | 1249 |
Slc7a5,Slc16a1,Ltbp2,Slc16a3,Slc7a2 |
| 1.818e-02 | -4.01 | GO_DEATH_RECEPTOR_ACTIVITY | MSigDB lists | GO_DEATH_RECEPTOR_ACTIVITY | 20 | 5 | 15632 | 1249 |
Tnfrsf14,Cd40,Fas,Tnfrsf8,Tnfrsf1b |
| 1.818e-02 | -4.01 | REACTOME_HS_GAG_DEGRADATION | MSigDB lists | REACTOME_HS_GAG_DEGRADATION | 20 | 5 | 15632 | 1249 |
Sdc4,Agrn,Gpc1,Sdc1,Sdc2 |
| 1.818e-02 | -4.01 | DALESSIO_TSA_RESPONSE | MSigDB lists | DALESSIO_TSA_RESPONSE | 20 | 5 | 15632 | 1249 |
Gadd45b,Atf3,Fos,Ppp1r15a,Maff |
| 1.818e-02 | -4.01 | GO_NEGATIVE_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | 20 | 5 | 15632 | 1249 |
Ptprj,Ezr,Plcl2,Ptpn2,Prnp |
| 1.818e-02 | -4.01 | GAVIN_PDE3B_TARGETS | MSigDB lists | GAVIN_PDE3B_TARGETS | 20 | 5 | 15632 | 1249 |
Tnfsf10,Ebi3,Il18,Fgl2,Il10 |
| 1.818e-02 | -4.01 | MEINHOLD_OVARIAN_CANCER_LOW_GRADE_DN | MSigDB lists | MEINHOLD_OVARIAN_CANCER_LOW_GRADE_DN | 20 | 5 | 15632 | 1249 |
Tpx2,Mcm6,Stard7,Stat1,Nck1 |
| 1.818e-02 | -4.01 | GO_PROTEIN_ADP_RIBOSYLATION | MSigDB lists | GO_PROTEIN_ADP_RIBOSYLATION | 20 | 5 | 15632 | 1249 |
Sirt1,Tiparp,Arf4,Parp10,Parp3 |
| 1.818e-02 | -4.01 | FERRANDO_TAL1_NEIGHBORS | MSigDB lists | FERRANDO_TAL1_NEIGHBORS | 20 | 5 | 15632 | 1249 |
Bcl2a1d,Bcl2a1a,Fcgr4,Bcl2a1b,Tnfrsf1b |
| 1.818e-02 | -4.01 | GO_PURINERGIC_NUCLEOTIDE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_PURINERGIC_NUCLEOTIDE_RECEPTOR_SIGNALING_PATHWAY | 20 | 5 | 15632 | 1249 |
P2ry13,P2ry14,Ptafr,P2ry2,P2ry12 |
| 1.818e-02 | -4.01 | GO_REGULATION_OF_ANOIKIS | MSigDB lists | GO_REGULATION_OF_ANOIKIS | 20 | 5 | 15632 | 1249 |
Notch1,Cav1,Itga5,Ptk2,Src |
| 1.818e-02 | -4.01 | GO_REGULATION_OF_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS | MSigDB lists | GO_REGULATION_OF_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS | 20 | 5 | 15632 | 1249 |
Timp1,Il10,Il1b,Tnf,Tnfrsf1b |
| 1.818e-02 | -4.01 | GO_NEGATIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY | 20 | 5 | 15632 | 1249 |
Notch1,Rabgef1,Abr,Stxbp3,Hmox1 |
| 1.829e-02 | -4.00 | ROSS_AML_WITH_AML1_ETO_FUSION | MSigDB lists | ROSS_AML_WITH_AML1_ETO_FUSION | 68 | 11 | 15632 | 1249 |
Ccnd1,Ciita,Cd34,Isg20,Clec5a,Itpr1,Cav1,Traf3ip2,Ptgir,Endod1,Ier2 |
| 1.829e-02 | -4.00 | YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP | MSigDB lists | YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP | 68 | 11 | 15632 | 1249 |
H2-Ab1,Arl4a,Actb,Gsta3,Me1,Flt1,Nr4a1,Lcn2,Csf3r,Gem,Pdpn |
| 1.829e-02 | -4.00 | PID_P75_NTR_PATHWAY | MSigDB lists | PID_P75_NTR_PATHWAY | 68 | 11 | 15632 | 1249 |
Birc3,Ikbkg,Sqstm1,Bcl2l11,Ripk2,Birc2,Myd88,Cycs,Casp3,Apaf1,Rhoc |
| 1.834e-02 | -4.00 | IK2_01 | MSigDB lists | IK2_01 | 242 | 29 | 15632 | 1249 |
Tnfsf15,Atxn7l1,Nrp2,Zeb1,Nfkbid,Jarid2,Ptch1,Cd86,Rbms1,Actb,Stip1,Agpat4,Igf1r,Dennd1b,Sat1,Tor1aip2,Cxcl14,Nfkbie,Psd,Parp8,Dock4,Rbms2,Relb,Tle3,Pdgfc,Prdm1,Slco3a1,Nr1h3,Sgms2 |
| 1.844e-02 | -3.99 | response to mechanical stimulus | biological process | GO:0009612 | 178 | 20 | 20694 | 1406 |
Cnn2,Tnf,Usp53,Piezo1,Cav1,Jun,Nfkb1,Fos,Stat1,Lrp11,Ptger4,Gfi1,Il18,Junb,Myc,Thbs1,Slc9a1,Cacnb3,Nfkbia,Htr2a |
| 1.844e-02 | -3.99 | stem cell differentiation | biological process | GO:0048863 | 178 | 20 | 20694 | 1406 |
Acvr1,Notch1,Hhex,Jarid2,Sema4a,Ednrb,Batf,Zfp281,Sema3c,Nrp2,Jag1,Kitl,Fzd1,Edn1,Htr2b,Sema4c,Hif1a,Phactr4,Cited2,Lif |
| 1.848e-02 | -3.99 | mitotic cell cycle process | biological process | GO:1903047 | 431 | 41 | 20694 | 1406 |
Pttg1,Gpsm2,Mcm6,Rhoc,Chmp4b,Mdm2,Gpr132,Ier3,Inhba,Spry2,Sbds,Crlf3,Ccng2,Cdkn2d,Ccnd1,Rgcc,Trip13,Ccne1,Cdkn1a,Pml,Casp2,Rbbp8,Ccnj,Acvr1,Hinfp,Rrs1,Pim2,Plk2,Mitd1,Trim36,Rhou,Plk3,Daxx,Mecp2,Atm,Abcb1a,Tpx2,Ccnd2,Cenpe,Acvr1b,Cenpj |
| 1.851e-02 | -3.99 | ROSS_AML_WITH_CBFB_MYH11_FUSION | MSigDB lists | ROSS_AML_WITH_CBFB_MYH11_FUSION | 51 | 9 | 15632 | 1249 |
Tnfaip2,Mdfic,Kctd12,Cebpd,S100a8,Il13ra1,Dusp6,Tgfbi,Lpar1 |
| 1.851e-02 | -3.99 | GO_NEURAL_CREST_CELL_MIGRATION | MSigDB lists | GO_NEURAL_CREST_CELL_MIGRATION | 51 | 9 | 15632 | 1249 |
Sema4c,Ednrb,Hif1a,Sema3c,Sema4a,Kitl,Acvr1,Phactr4,Htr2b |
| 1.851e-02 | -3.99 | GENTILE_UV_RESPONSE_CLUSTER_D4 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D4 | 51 | 9 | 15632 | 1249 |
Sec24b,Eef1e1,Rapgef2,Zfp36,Spen,Cdc42ep4,Arid5b,Tpst1,Filip1l |
| 1.851e-02 | -3.99 | HUTTMANN_B_CLL_POOR_SURVIVAL_DN | MSigDB lists | HUTTMANN_B_CLL_POOR_SURVIVAL_DN | 51 | 9 | 15632 | 1249 |
Fut8,Rras2,Akt3,Egr3,Slc4a7,Ptk2,Birc3,Casp1,Smc5 |
| 1.851e-02 | -3.99 | MODULE_277 | MSigDB lists | MODULE_277 | 51 | 9 | 15632 | 1249 |
Lnpep,Usp25,Scyl2,Smc5,Ankrd17,Slc16a1,Dr1,Vcpip1,G3bp2 |
| 1.852e-02 | -3.99 | positive regulation of growth | biological process | GO:0045927 | 308 | 31 | 20694 | 1406 |
Hopx,Stat5a,Hlx,Mul1,Ptger4,Mecp2,Cyfip1,Eif4g2,Ezr,Serp1,Ikzf1,Adrb2,Nr3c1,Cd38,Slc9a1,Psmd10,Csf1,Pim1,Ahr,Serpine1,Edn1,Dbnl,Sphk1,Hmga2,Notch1,Agrn,Ptk2,C3,Mmp14,Trip10,Sirt1 |
| 1.852e-02 | -3.99 | multicellular organismal homeostasis | biological process | GO:0048871 | 308 | 31 | 20694 | 1406 |
Kdr,Col11a2,Il1a,Src,Met,Stat3,Gcnt2,Adrb2,Tlr9,Cd34,Ampd3,Pla2g4a,Snx10,Homer1,Prdx5,Nr4a3,Egr1,Csf1,Nod2,Sirt1,Acp5,Pdgfrb,Htr2a,Vps54,Slc28a2,Notch1,Il1rn,Chmp4b,Rac3,Il1b,Akt3 |
| 1.853e-02 | -3.99 | Interleukin receptor SHC signaling | REACTOME pathways | R-MMU-912526 | 221 | 29 | 8608 | 757 |
Pdgfb,Kitl,Spred1,Irs2,Ppp2r5a,Src,Psme2b,Angpt1,Pdgfrb,Il2rg,Ksr1,Map2k1,Jak2,Ppp2r1b,Psmb8,Ptk2,Met,Psmb10,Psma6,Psme2,Psmd10,Psmb9,Rasgrp1,Pik3cd,Rapgef2,Dusp6,Psmb6,Dusp5,Psme1 |
| 1.853e-02 | -3.99 | Prolonged ERK activation events | REACTOME pathways | R-MMU-169893 | 221 | 29 | 8608 | 757 |
Psmb9,Rasgrp1,Rapgef2,Dusp6,Crkl,Psmb6,Dusp5,Psme1,Psmb8,Ptk2,Met,Psmb10,Psma6,Psme2,Psmd10,Pdgfrb,Il2rg,Ksr1,Map2k1,Jak2,Ppp2r1b,Pdgfb,Kitl,Spred1,Irs2,Ppp2r5a,Src,Psme2b,Angpt1 |
| 1.859e-02 | -3.99 | lipid localization | biological process | GO:0010876 | 296 | 30 | 20694 | 1406 |
Inhba,Atp11a,Cav1,Msr1,Slco3a1,Il1b,Fabp3,Gramd1a,Acsl5,Lipg,Abcc4,Nos2,Tnf,Stard7,Tspo,Atp11b,Stat5a,Acsl1,Abcb1a,Osbpl3,Atp10a,Pla2g4a,Ldlr,Abcc1,Xkr8,4932438A13Rik,Stoml1,Stra6l,Plscr1,Stard5 |
| 1.860e-02 | -3.98 | GO_WATER_SOLUBLE_VITAMIN_METABOLIC_PROCESS | MSigDB lists | GO_WATER_SOLUBLE_VITAMIN_METABOLIC_PROCESS | 77 | 12 | 15632 | 1249 |
Nampt,Psat1,Mthfd1l,Mthfr,Acpp,Ptgs2,Slc2a1,Mthfd2,Pdzd11,Gclc,Pcx,Abcc1 |
| 1.860e-02 | -3.98 | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | MSigDB lists | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | 77 | 12 | 15632 | 1249 |
Pf4,Prkar2b,Cd38,Serpinb2,Asf1a,Il1rn,Minpp1,Casp3,Hdc,Jun,Ccl5,Apobec3 |
| 1.860e-02 | -3.98 | PID_P73PATHWAY | MSigDB lists | PID_P73PATHWAY | 77 | 12 | 15632 | 1249 |
Cdkn1a,Il4ra,Fas,Plk3,Pml,Mdm2,Sirt1,Casp2,Myc,Serpine1,Bcl2l11,Gdf15 |
| 1.861e-02 | -3.98 | AACTGAC_MIR223 | MSigDB lists | AACTGAC_MIR223 | 86 | 13 | 15632 | 1249 |
Nlrp3,Sgms2,Fignl2,Kpna3,Hhex,Prdm1,Plagl2,Crim1,Spred1,Igf1r,Rnf34,Ankrd17,Inpp5b |
| 1.861e-02 | -3.98 | GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE | MSigDB lists | GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE | 86 | 13 | 15632 | 1249 |
Atm,Cenpj,Plk2,Btg2,Casp2,Mdm2,Cnot4,Pml,Plk3,Plagl1,Batf,Tnks1bp1,Cdkn1a |
| 1.861e-02 | -3.98 | GO_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS | 86 | 13 | 15632 | 1249 |
Nqo1,Psma6,Psme2,Pde1b,Psmb9,Psmd10,Psmb8,Atp2b4,Ldlr,Odc1,Psmb10,Psme1,Psmb6 |
| 1.861e-02 | -3.98 | ZHU_CMV_24_HR_DN | MSigDB lists | ZHU_CMV_24_HR_DN | 86 | 13 | 15632 | 1249 |
Igf1r,Ahr,Ldlr,Thbs1,Lox,Vcan,Ccnd1,C1ra,Nr3c1,Serpine1,Cnn2,Hivep2,Tagln |
| 1.861e-02 | -3.98 | chaperone-mediated protein folding | biological process | GO:0061077 | 50 | 8 | 20694 | 1406 |
Cd74,Dnajb2,Ero1l,Hsph1,Hspa2,Hspa1b,Dnajb4,Hspa1a |
| 1.867e-02 | -3.98 | regulation of cellular component size | biological process | GO:0032535 | 394 | 38 | 20694 | 1406 |
Rap1gap2,Dbnl,Ifrd1,Edn1,Sema4c,Carmil1,Tmsb10,Rictor,Ahr,Myadm,Icam1,Tlr2,Cdk5r1,Prkce,Spire1,Slc12a9,Swap70,Ppp1r15a,Akt3,Rac3,Cyfip1,Vasp,Fchsd2,Tmod3,Sema3c,Nck1,Evl,Whamm,Csf3,Plek,Cdc42ep2,Cdc42ep4,Rab21,Ezr,Sema4a,Eif4g2,Tmem123,Hcls1 |
| 1.868e-02 | -3.98 | GO_VESICLE_MEDIATED_TRANSPORT | MSigDB lists | GO_VESICLE_MEDIATED_TRANSPORT | 1102 | 107 | 15632 | 1249 |
Thbs1,Vegfc,Abcc4,Sec24b,Pf4,Cd55,Scyl2,Chic2,Kif3c,Ptafr,Pdgfb,Ranbp2,Adora2a,Hap1,Stx11,Snx10,Tuba4a,Myo1b,Hck,Myo10,Itga4,Calcrl,Fgr,Jmjd6,Dennd1b,Rab9,Dbnl,Ly75,Tapbp,Src,Axl,Dync1h1,Ehd1,Hsph1,Ppp6r1,Lrp4,Timp1,Actb,Tnfaip2,Ap3m2,Adrb2,Pik3cd,Rasgrp1,Rabgef1,Marco,Irf8,Rims3,Fcgr1,Chmp4b,Mapkapk2,Lrp8,Prkce,Cenpe,Ezr,Cyfip1,Msr1,Pcdh7,Mitd1,Sec24a,Htr2b,Xkr8,Hp,Fcho2,Nr4a3,Spire1,Rab10,Pdlim7,Stxbp3,Sh3bp4,Snx2,Plek,Ccr1,Ccl5,Golga3,Vps54,Serpine1,Cd14,Rab3ip,Micall2,Rab11fip1,Cd302,Whamm,Arf4,Ldlr,Ptk2,Dennd2a,Mppe1,Rab20,Lyn,Pdzd11,Stx6,Cav1,F10,Olr1,Nck1,Stxbp1,Cyth3,Pikfyve,Nr1h3,Ctsc,Ap3b1,Rin2,Optn,Scarf1,Syk,Itgav,Trip10 |
| 1.871e-02 | -3.98 | cysteine-type endopeptidase regulator activity involved in apoptotic process | molecular function | GO:0043028 | 40 | 7 | 20217 | 1400 |
Serpinb9,Birc3,Tnfsf14,Birc2,Apaf1,Bcl2a1d,Prdx5 |
| 1.873e-02 | -3.98 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_0.8H_DN | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_0.8H_DN | 162 | 21 | 15632 | 1249 |
Tmem176a,Gpr68,Il12rb1,Fgl2,Sele,Bst1,Chst11,Il18bp,Ccr3,Ext1,Cacybp,Dusp6,Cdkn1a,Hcls1,Kitl,Pcdh7,Vcam1,Frmd4a,Cacnb3,Slamf8,Clec5a |
| 1.873e-02 | -3.98 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_0.8H_UP | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_0.8H_UP | 162 | 21 | 15632 | 1249 |
Psme2,Piezo1,Alas1,Noc4l,Spint2,Etv6,Gsdmd,Ttc9c,Slc4a7,Ccl5,Ppp1r15b,Rhof,Nfxl1,Cutc,Pdgfc,Ppfibp2,Palld,Phyh,Ccl22,Asb13,Slco3a1 |
| 1.874e-02 | -3.98 | GTGGGTGK_UNKNOWN | MSigDB lists | GTGGGTGK_UNKNOWN | 263 | 31 | 15632 | 1249 |
Zhx2,Notch2,Col27a1,Nr4a3,Sema4c,Egr3,Uchl1,Slc25a12,Sirt1,Pdgfb,Gpr132,Serpine1,Osm,Dcun1d3,Klf7,Atp2b4,Myo10,Ubash3b,Cyth3,Ccl22,Pigv,Socs1,Egr1,Bcor,Zfp800,Kremen1,Nr3c1,Prkce,Mtus1,Itpr1,Tmem184b |
| 1.889e-02 | -3.97 | GSE32533_WT_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP | MSigDB lists | GSE32533_WT_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP | 172 | 22 | 15632 | 1249 |
Abcc1,Tnks1bp1,Stau1,Extl2,Rcan1,Phf6,Ell2,Cdkn2d,Smc5,Bcor,Ift57,B3gnt5,Mdm2,Fgl2,Kdm5b,Nfkbid,Rab11fip1,Csf1,Ksr1,Rab21,Tnfsf14,Il10 |
| 1.892e-02 | -3.97 | TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 | MSigDB lists | TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 | 541 | 57 | 15632 | 1249 |
Spen,Akt3,Rictor,Mmd,Ccne1,Dach1,Ptch1,Pid1,Rap2c,Zcchc2,Sh3bgrl2,Adrb2,Acsl1,Kcnj2,Cpd,Scarf1,Hmga1,Trip10,Zyx,Casz1,Cdc42ep2,Spred1,Usp25,Stxbp1,Cdk5r1,Cx3cl1,Ccnd2,Phip,Stxbp3,Piezo1,Phlpp2,Nrp2,Btg2,Rab10,Slc4a7,Slc13a3,Map2k1,Slc7a2,Higd1a,Rsbn1,Dcbld2,Pcgf5,Crkl,Nr4a3,Mob3b,Pim1,Usp42,Ak4,N4bp1,Abcc5,Itpr1,Bfar,Prpf38a,Crim1,Clcn5,Cd164,Fam133b |
| 1.893e-02 | -3.97 | Macrophage markers | WikiPathways | WP2271 | 10 | 4 | 4813 | 540 |
Cd86,Cd14,Cd74,Cd83 |
| 1.895e-02 | -3.97 | AFFAR_YY1_TARGETS_UP | MSigDB lists | AFFAR_YY1_TARGETS_UP | 202 | 25 | 15632 | 1249 |
Uchl1,Cd55,Casp7,Itga9,Kdr,Cdkn1a,Plod2,Ppp1r15a,Btg2,Fas,Fabp3,Icam1,Rnd3,Tap1,Abcc5,Src,Ehd1,Flt1,Dusp1,B4galt4,Fos,Gbp9,Gbp4,Gadd45g,Mdm2 |
| 1.896e-02 | -3.97 | REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING | MSigDB lists | REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING | 35 | 7 | 15632 | 1249 |
Cdkn1a,Mdm2,Phlpp1,Rictor,Akt3,Trib3,Nr4a1 |
| 1.896e-02 | -3.97 | BIOCARTA_FCER1_PATHWAY | MSigDB lists | BIOCARTA_FCER1_PATHWAY | 35 | 7 | 15632 | 1249 |
Pla2g4a,Fos,Lyn,Map2k4,Jun,Map2k1,Syk |
| 1.896e-02 | -3.97 | VANASSE_BCL2_TARGETS_UP | MSigDB lists | VANASSE_BCL2_TARGETS_UP | 35 | 7 | 15632 | 1249 |
Slpi,Il1rn,Pilra,Socs3,Prdm1,Map3k6,Hspa1a |
| 1.896e-02 | -3.97 | HUANG_FOXA2_TARGETS_DN | MSigDB lists | HUANG_FOXA2_TARGETS_DN | 35 | 7 | 15632 | 1249 |
Plaur,Tgfbi,Atp2b4,Cdkn1a,Cxcl1,Tnc,Plat |
| 1.896e-02 | -3.97 | GO_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY | MSigDB lists | GO_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY | 35 | 7 | 15632 | 1249 |
Clcf1,Il10,Cd40,Bcl6,Tnf,Tnfsf4,C3 |
| 1.896e-02 | -3.97 | HALLMARK_HEDGEHOG_SIGNALING | MSigDB lists | HALLMARK_HEDGEHOG_SIGNALING | 35 | 7 | 15632 | 1249 |
Pml,Rtn1,Cdk5r1,Ptch1,Ets2,Nrp2,Tle3 |
| 1.896e-02 | -3.97 | GO_REGULATION_OF_STEROL_TRANSPORT | MSigDB lists | GO_REGULATION_OF_STEROL_TRANSPORT | 35 | 7 | 15632 | 1249 |
Nr1h3,Ptch1,Nfkb1,Nfkbia,Sirt1,Lipg,Tspo |
| 1.896e-02 | -3.97 | GO_POSITIVE_REGULATION_OF_VASOCONSTRICTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_VASOCONSTRICTION | 35 | 7 | 15632 | 1249 |
Cav1,Ptgs2,Icam1,Ptafr,Gja1,Cd38,Htr2a |
| 1.896e-02 | -3.97 | regulation of regulated secretory pathway | biological process | GO:1903305 | 190 | 21 | 20694 | 1406 |
Rabgef1,P2ry2,Adora2a,Prkce,Hmox1,Cacna1d,Lyn,Abr,Il4ra,Stxbp1,Rims3,Stxbp3,Ptafr,Fgr,Syk,Notch1,Lgals9,Adora2b,Apba1,Adrb2,Htr2a |
| 1.896e-02 | -3.97 | response to steroid hormone | biological process | GO:0048545 | 190 | 21 | 20694 | 1406 |
Tnf,Lox,Daxx,Fas,Nr4a3,Cav1,Ifnb1,Jak2,Acod1,Il6,Dnaja1,Il1rn,Nr4a1,Ddit4,Ass1,Map2k1,Nr1h3,Il10,Src,Zfp36,Nr3c1 |
| 1.898e-02 | -3.96 | GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN | MSigDB lists | GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN | 182 | 23 | 15632 | 1249 |
Jun,Minpp1,Il6,Atf3,Lif,Prdx1,Trp53i11,Slc16a1,Gys1,Fcgr4,Eno2,Tuba4a,Tnfsf14,Rel,Gem,Phlpp2,Bst1,St3gal1,Acsl1,Pcdh7,Adam19,Dcbld2,Socs7 |
| 1.898e-02 | -3.96 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4_KO_BCELL_DN | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4_KO_BCELL_DN | 182 | 23 | 15632 | 1249 |
Agpat4,Cdkn1a,Tnfaip3,Gnb4,Ubash3b,Nr4a3,Mpp7,Pgs1,Mxd1,Rhoh,Bcor,Col18a1,Rnf19a,Hap1,Phactr4,Cnn3,Tbc1d1,Il4i1,Samsn1,Gadd45b,Gch1,Trmt1l,Sqstm1 |
| 1.898e-02 | -3.96 | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_UP | 182 | 23 | 15632 | 1249 |
Il18,Slco3a1,Trim12c,Calcrl,Tmem229b,Cd200,Hlx,Hk3,Hdc,Tap2,Gdf15,Ccl5,Il18rap,Psma6,Mlkl,Psme2,Setdb2,Minpp1,Trim14,Gclm,Parp14,Casp3,Pla2g4a |
| 1.898e-02 | -3.96 | GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY40_UP | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY40_UP | 182 | 23 | 15632 | 1249 |
Gys1,Ube2f,Hif1a,Gmppb,Arrdc4,Slc30a4,Tmem176b,Pgs1,Dtnb,Irgm2,Gpr35,Armcx6,Parp8,Ddhd1,Glrx,Rnf19b,Rtn1,Snx2,Ext1,Slc7a5,Lap3,Hsd17b12,Jarid2 |
| 1.898e-02 | -3.96 | GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 182 | 23 | 15632 | 1249 |
Sat1,Csf1,Pstpip2,Chst11,Txnrd1,Jarid2,Mfap3l,Crbn,Nampt,P2ry13,D16Ertd472e,C1rl,Sema3c,Rap2c,Cflar,Cxcl1,Pdgfc,Cd55,Mxd1,P2ry14,Pikfyve,Prnp,Pim1 |
| 1.898e-02 | -3.96 | GSE3039_B2_VS_B1_BCELL_DN | MSigDB lists | GSE3039_B2_VS_B1_BCELL_DN | 182 | 23 | 15632 | 1249 |
Bambi,Frmd6,Hsd17b7,Igf2bp2,Ppa1,Ldha,C3,Fpr1,Nr4a3,Clec5a,Fam72a,Slc39a14,Ccne1,Hopx,Vezt,1600014C10Rik,Tal2,Tpi1,Il4ra,Fpr2,Slc39a4,Txnrd1,Rapgef5 |
| 1.898e-02 | -3.96 | GSE13306_TREG_VS_TCONV_SPLEEN_DN | MSigDB lists | GSE13306_TREG_VS_TCONV_SPLEEN_DN | 182 | 23 | 15632 | 1249 |
4932438A13Rik,Fgl2,Plekha5,Otud1,Acpp,Dse,Ahr,Evl,Mcoln2,Agtrap,St3gal6,Slco3a1,Clec4n,Psat1,Ttc9c,Lnpep,Ahrr,Card6,Sesn3,Slfn4,Slfn3,Epsti1,Pim2 |
| 1.898e-02 | -3.96 | GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_DN | 182 | 23 | 15632 | 1249 |
Slfn4,Zc3h12c,Slc12a9,Clec4n,Hivep3,Procr,Reps1,Phlda1,Ier3,Larp1,Cdkn1a,Plcl2,Slfn3,Cd82,Asf1a,Hspa2,Gclm,Agtrap,Nr1h3,Marcksl1,Ifit1,Prdx1,Gng11 |
| 1.898e-02 | -3.96 | GO_FEMALE_SEX_DIFFERENTIATION | MSigDB lists | GO_FEMALE_SEX_DIFFERENTIATION | 114 | 16 | 15632 | 1249 |
Pla2g4a,Mmp14,Inhba,Mmp13,Sirt1,Casp2,Axl,Dach1,Ccne1,Tiparp,Kitl,Ahr,Fas,Acvr1b,Icam1,Arid5b |
| 1.899e-02 | -3.96 | GO_REGULATION_OF_PEPTIDE_SECRETION | MSigDB lists | GO_REGULATION_OF_PEPTIDE_SECRETION | 192 | 24 | 15632 | 1249 |
Cd38,Slc16a1,Pim3,Irs2,Cd74,Hif1a,Lif,Gpr68,Prkce,Serp1,Slc2a1,Itpr1,Tnf,Il1b,Nlgn2,Pfkl,Cacna1d,Jak2,Ptger4,Nos2,Ccl5,Gja1,H2-Eb1,S100a8 |
| 1.899e-02 | -3.96 | GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | MSigDB lists | GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | 192 | 24 | 15632 | 1249 |
St3gal1,Fam20c,Ldlr,Tnip1,Clcn7,Gfi1,Ptges,Dio2,Tuba4a,Ccl5,Igsf8,Sema3c,Ampd3,Trim21,Vasp,Nek6,Mthfr,Nfkbiz,Pgs1,F11r,Usp18,Cited2,Pdpn,Tor1aip2 |
| 1.899e-02 | -3.96 | GO_MULTI_MULTICELLULAR_ORGANISM_PROCESS | MSigDB lists | GO_MULTI_MULTICELLULAR_ORGANISM_PROCESS | 192 | 24 | 15632 | 1249 |
Fos,Ccl12,Pla2g4a,Edn1,Hif1a,Sphk1,Fas,Prdm1,Lif,Cd38,Plau,Fosb,Junb,Clic5,Nampt,Lnpep,Mmp13,Maff,Ptgs2,Ptafr,Adrb2,Ptger4,Mmp9,Il1b |
| 1.902e-02 | -3.96 | posttranscriptional regulation of gene expression | biological process | GO:0010608 | 482 | 45 | 20694 | 1406 |
Thbs1,Nck1,Cpeb4,Gtpbp2,Dcp2,Tut7,Klhl25,Gcnt2,Serp1,Stat3,Noct,Myd88,Fam129a,Fbxo4,Pml,Ppp1r15b,Ago3,Eif4g2,Il6,Tent4a,Cyfip1,Mov10,Plekhn1,Ptafr,Parp9,Tnf,Eif2ak2,Ythdf1,Btg2,Carhsp1,Zc3h12a,Ppp1r15a,Tnfrsf1b,Rnf139,Zfp36,Polr2g,Mapkapk2,Tent2,Larp1,Tdrd7,Igf2bp2,Xrn1,Cav1,Zc3h7a,Adar |
| 1.903e-02 | -3.96 | camera-type eye development | biological process | GO:0043010 | 333 | 33 | 20694 | 1406 |
Zeb1,Rpgrip1l,Fzd5,Slc4a7,Pdgfrb,Jmjd6,Zhx2,Notch2,Inhba,Rcn1,Ahr,Tdrd7,Clic4,Tsku,Gja1,Zfp513,Lhx2,Hdac1,Ikzf1,Acvrl1,Jun,Jag1,Gpd2,Phactr4,Pdgfb,Tulp3,Lif,Cited2,Slc25a25,Casz1,Hif1a,Flt1,Kdr |
| 1.903e-02 | -3.96 | regulation of intracellular transport | biological process | GO:0032386 | 333 | 33 | 20694 | 1406 |
Src,Ccl2,Angpt1,Prnp,Cacnb3,Map2k1,Hcls1,Ezr,Rab21,Hap1,Adora2b,Stxbp1,Syk,Mecp2,Mdfic,Plk3,Gbp4,Ptgs2,Ehd1,Rnf139,Ier3,Zc3h12a,Sec24b,Mdm2,Txn1,Dync1h1,Uaca,Fgr,Cdk5r1,Hmox1,Rabgef1,Il4ra,Lyn |
| 1.903e-02 | -3.96 | TATA_C | MSigDB lists | TATA_C | 253 | 30 | 15632 | 1249 |
Tshz1,Gch1,Jarid2,Pdgfrb,Ubr4,Mmp13,Hivep3,Rtn1,Lox,Kcna3,Kitl,Actb,Prkar2b,Il1b,Dio2,Agpat4,H3f3b,Tagln,Tcf4,Bnip3,Gadd45g,Errfi1,Rhoh,Prdm1,Atf3,Pbx1,Ube2f,Cdc42ep2,Prpf4,Tle3 |
| 1.906e-02 | -3.96 | TSUNODA_CISPLATIN_RESISTANCE_DN | MSigDB lists | TSUNODA_CISPLATIN_RESISTANCE_DN | 43 | 8 | 15632 | 1249 |
Ell2,Ass1,C3,Ptgs2,Cd74,Itpr1,Slc7a5,Ptges |
| 1.906e-02 | -3.96 | GYORFFY_DOXORUBICIN_RESISTANCE | MSigDB lists | GYORFFY_DOXORUBICIN_RESISTANCE | 43 | 8 | 15632 | 1249 |
Angpt1,Abcb1a,Bmp2,Cish,Znrf3,Cdyl,Map4k4,Casp1 |
| 1.906e-02 | -3.96 | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP | MSigDB lists | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP | 43 | 8 | 15632 | 1249 |
Msr1,Pttg1,Slfn4,Tlr6,Gng12,Dio2,Gnb4,Slfn3 |
| 1.906e-02 | -3.96 | PID_DELTA_NP63_PATHWAY | MSigDB lists | PID_DELTA_NP63_PATHWAY | 43 | 8 | 15632 | 1249 |
Axl,Atm,Il1a,Ppp2r5a,Mdm2,Notch1,Pou2f2,Cebpd |
| 1.908e-02 | -3.96 | regulation of epidermis development | biological process | GO:0045682 | 80 | 11 | 20694 | 1406 |
Maff,Tnf,Keap1,Notch1,Inhba,Klf7,Mafg,Ptch1,Errfi1,Zfp36,Mycl |
| 1.910e-02 | -3.96 | protein kinase complex | cellular component | GO:1902911 | 101 | 13 | 20747 | 1409 |
Acvrl1,Ccnj,Igf1r,Cdk5r1,Acvr1b,Cdkn1a,Cdkn2d,Ccne1,Ccng2,Ccnd2,Ccnd1,Ikbkg,Acvr1 |
| 1.911e-02 | -3.96 | PH_DOMAIN | prosite domains | PS50003 | 238 | 28 | 13278 | 1037 |
Arhgap26,Osbpl3,Cyth3,Swap70,Triobp,Phlpp1,Dock10,Abr,Akt3,Plekhf2,Asap3,Plekha4,Dgkh,Adap2,Stap1,Irs2,Plcl2,Plekha2,Plekhg1,Phldb1,Myo10,Psd4,Psd,Plek,Spata13,Plekha5,Grk3,Arhgef3 |
| 1.916e-02 | -3.95 | - | gene3d domains | 2.130.10.130 | 19 | 5 | 8819 | 755 |
Itga4,Itgal,Itga5,Itgav,Itga9 |
| 1.918e-02 | -3.95 | embryonic placenta morphogenesis | biological process | GO:0060669 | 32 | 6 | 20694 | 1406 |
Socs3,Spint2,Vcam1,Fzd5,Il10,Itga4 |
| 1.918e-02 | -3.95 | regulation of vascular endothelial growth factor receptor signaling pathway | biological process | GO:0030947 | 32 | 6 | 20694 | 1406 |
Hif1a,Angpt1,Hhex,Flt1,Kdr,Vegfc |
| 1.918e-02 | -3.95 | regulation of smooth muscle cell differentiation | biological process | GO:0051150 | 32 | 6 | 20694 | 1406 |
Sirt1,Ankrd17,Mecp2,Pdgfb,Zeb1,Sod2 |
| 1.918e-02 | -3.95 | positive T cell selection | biological process | GO:0043368 | 32 | 6 | 20694 | 1406 |
Il6,Spn,Irf4,Stat3,Batf,Cd74 |
| 1.918e-02 | -3.95 | cell differentiation involved in embryonic placenta development | biological process | GO:0060706 | 32 | 6 | 20694 | 1406 |
Fzd5,Itgav,Spint2,Socs3,Prdm1,Lif |
| 1.918e-02 | -3.95 | regulation of membrane repolarization | biological process | GO:0060306 | 32 | 6 | 20694 | 1406 |
Scn1b,Cacnb3,Gja1,Cav1,Cacna1d,Kcnj2 |
| 1.922e-02 | -3.95 | Nucleotide sugar biosynthesis, glucose => UDP-glucose | KEGG pathways | M00549 | 7 | 3 | 7931 | 713 |
Hk3,Hk2,Hk1 |
| 1.922e-02 | -3.95 | Nucleotide sugar biosynthesis, glucose => UDP-glucose | KEGG pathways | mmu_M00549 | 7 | 3 | 7931 | 713 |
Hk1,Hk3,Hk2 |
| 1.928e-02 | -3.95 | common bile duct development | biological process | GO:0061009 | 9 | 3 | 20694 | 1406 |
Hhex,Ahr,Notch2 |
| 1.928e-02 | -3.95 | regulation of chloride transport | biological process | GO:2001225 | 9 | 3 | 20694 | 1406 |
Abcb1a,Prnp,Ptafr |
| 1.928e-02 | -3.95 | response to epinephrine | biological process | GO:0071871 | 9 | 3 | 20694 | 1406 |
Atp2b4,Pde4b,Slc9a1 |
| 1.928e-02 | -3.95 | negative regulation of immunoglobulin mediated immune response | biological process | GO:0002890 | 9 | 3 | 20694 | 1406 |
Bcl6,Parp3,Fcgr2b |
| 1.928e-02 | -3.95 | regulation of gamma-delta T cell activation | biological process | GO:0046643 | 9 | 3 | 20694 | 1406 |
Stat5a,Syk,Egr3 |
| 1.928e-02 | -3.95 | regulation of toll-like receptor 9 signaling pathway | biological process | GO:0034163 | 9 | 3 | 20694 | 1406 |
Treml4,Rsad2,Tlr9 |
| 1.928e-02 | -3.95 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902237 | 9 | 3 | 20694 | 1406 |
Sirt1,Ptpn2,Nck1 |
| 1.928e-02 | -3.95 | cellular response to muramyl dipeptide | biological process | GO:0071225 | 9 | 3 | 20694 | 1406 |
Nod1,Nod2,Ripk2 |
| 1.928e-02 | -3.95 | positive regulation of viral entry into host cell | biological process | GO:0046598 | 9 | 3 | 20694 | 1406 |
Trim30a,Trim21,Cd74 |
| 1.928e-02 | -3.95 | negative regulation of B cell mediated immunity | biological process | GO:0002713 | 9 | 3 | 20694 | 1406 |
Fcgr2b,Parp3,Bcl6 |
| 1.928e-02 | -3.95 | negative regulation of extracellular matrix organization | biological process | GO:1903054 | 9 | 3 | 20694 | 1406 |
Antxr1,Tnfrsf1b,Notch1 |
| 1.928e-02 | -3.95 | neutrophil activation involved in immune response | biological process | GO:0002283 | 9 | 3 | 20694 | 1406 |
Stx11,Syk,Dnase1l3 |
| 1.928e-02 | -3.95 | regulation of gamma-delta T cell differentiation | biological process | GO:0045586 | 9 | 3 | 20694 | 1406 |
Egr3,Syk,Stat5a |
| 1.928e-02 | -3.95 | positive regulation of monocyte differentiation | biological process | GO:0045657 | 9 | 3 | 20694 | 1406 |
Csf1,Cd74,Jun |
| 1.928e-02 | -3.95 | positive regulation of unsaturated fatty acid biosynthetic process | biological process | GO:2001280 | 9 | 3 | 20694 | 1406 |
Pla2g4a,Ptgs2,Il1b |
| 1.928e-02 | -3.95 | inhibition of cysteine-type endopeptidase activity | biological process | GO:0097340 | 9 | 3 | 20694 | 1406 |
Birc2,Birc3,Cst7 |
| 1.928e-02 | -3.95 | positive regulation of vasculogenesis | biological process | GO:2001214 | 9 | 3 | 20694 | 1406 |
Kdr,Rapgef2,Cd34 |
| 1.928e-02 | -3.95 | regulation of hepatic stellate cell activation | biological process | GO:2000489 | 9 | 3 | 20694 | 1406 |
Gclc,Pdgfrb,Pdgfb |
| 1.928e-02 | -3.95 | regulation of hyaluronan biosynthetic process | biological process | GO:1900125 | 9 | 3 | 20694 | 1406 |
Ptger4,Pdgfb,Nfkb1 |
| 1.928e-02 | -3.95 | regulation of interleukin-1 alpha production | biological process | GO:0032650 | 9 | 3 | 20694 | 1406 |
Cx3cl1,Casp1,Ptger4 |
| 1.928e-02 | -3.95 | adenosine receptor signaling pathway | biological process | GO:0001973 | 9 | 3 | 20694 | 1406 |
Adora2a,P2ry12,Adora2b |
| 1.928e-02 | -3.95 | regulation of protein complex stability | biological process | GO:0061635 | 9 | 3 | 20694 | 1406 |
Irgm2,Sqstm1,Tapbp |
| 1.928e-02 | -3.95 | retinal bipolar neuron differentiation | biological process | GO:0060040 | 9 | 3 | 20694 | 1406 |
Zhx2,Casz1,Ikzf1 |
| 1.928e-02 | -3.95 | regulation of blood vessel remodeling | biological process | GO:0060312 | 9 | 3 | 20694 | 1406 |
Abr,Gja1,Il18 |
| 1.928e-02 | -3.95 | negative regulation of striated muscle contraction | biological process | GO:0045988 | 9 | 3 | 20694 | 1406 |
Pde5a,Zc3h12a,Arg2 |
| 1.928e-02 | -3.95 | positive regulation of myeloid cell apoptotic process | biological process | GO:0033034 | 9 | 3 | 20694 | 1406 |
Hcar2,Sirt1,Pik3cd |
| 1.928e-02 | -3.95 | antigen processing and presentation of exogenous peptide antigen via MHC class I | biological process | GO:0042590 | 9 | 3 | 20694 | 1406 |
Fcgr1,Tapbp,Tap1 |
| 1.928e-02 | -3.95 | regulation of protein K63-linked ubiquitination | biological process | GO:1900044 | 9 | 3 | 20694 | 1406 |
Nod2,Birc2,Parp10 |
| 1.928e-02 | -3.95 | zymogen inhibition | biological process | GO:0097341 | 9 | 3 | 20694 | 1406 |
Birc3,Cst7,Birc2 |
| 1.928e-02 | -3.95 | smooth muscle cell migration | biological process | GO:0014909 | 9 | 3 | 20694 | 1406 |
Plat,Pdgfrb,Plau |
| 1.928e-02 | -3.95 | interleukin-1 beta secretion | biological process | GO:0050702 | 9 | 3 | 20694 | 1406 |
Aim2,Tlr6,Nlrc4 |
| 1.928e-02 | -3.95 | cellular response to epinephrine stimulus | biological process | GO:0071872 | 9 | 3 | 20694 | 1406 |
Pde4b,Slc9a1,Atp2b4 |
| 1.928e-02 | -3.95 | negative regulation of myeloid leukocyte mediated immunity | biological process | GO:0002887 | 9 | 3 | 20694 | 1406 |
Hmox1,Rabgef1,Abr |
| 1.928e-02 | -3.95 | visceral serous pericardium development | biological process | GO:0061032 | 9 | 3 | 20694 | 1406 |
Pdpn,Vcam1,Itga4 |
| 1.928e-02 | -3.95 | regulation of natural killer cell proliferation | biological process | GO:0032817 | 9 | 3 | 20694 | 1406 |
Il12b,Il15,Il18 |
| 1.930e-02 | -3.95 | MHC_I_a_a1/a2 | interpro domains | IPR001039 | 39 | 7 | 19984 | 1430 |
H2-T10,H2-Q4,H2-Q7,H2-Q6,H2-M2,H2-T24,H2-T22 |
| 1.930e-02 | -3.95 | Cyclin-like_sf | interpro domains | IPR036915 | 39 | 7 | 19984 | 1430 |
Ccnd1,Cdk5r1,Rbl1,Ccne1,Ccnj,Ccng2,Ccnd2 |
| 1.931e-02 | -3.95 | regulation of cell cycle arrest | biological process | GO:0071156 | 60 | 9 | 20694 | 1406 |
Sde2,Mdm2,Ccnd1,Cdk5r1,Rgcc,Crlf3,Cdkn1a,Casp2,Pml |
| 1.935e-02 | -3.95 | ARPC5L (actin related protein 2/3 complex subunit 5 like) | protein interactions | 81873 | 17 | 5 | 7778 | 753 |
Itga5,Actb,Tpx2,Flnb,Tmod3 |
| 1.935e-02 | -3.95 | CYBRD1 (cytochrome b reductase 1) | protein interactions | 79901 | 17 | 5 | 7778 | 753 |
Actb,Rmdn3,Tmod3,Chmp4b,Flnb |
| 1.935e-02 | -3.95 | Pfn2 (profilin 2) | protein interactions | 18645 | 17 | 5 | 7778 | 753 |
Hspa1b,Actb,Cyfip1,Evl,Vasp |
| 1.935e-02 | -3.95 | negative regulation of response to endoplasmic reticulum stress | biological process | GO:1903573 | 41 | 7 | 20694 | 1406 |
Usp25,Bfar,Nck1,Ppp1r15a,Ikbkg,Grina,Ppp1r15b |
| 1.935e-02 | -3.95 | positive regulation of fatty acid metabolic process | biological process | GO:0045923 | 41 | 7 | 20694 | 1406 |
Il1b,Pla2g4a,Ptgs2,Nr1h3,Nr4a3,Irs2,Acsl5 |
| 1.935e-02 | -3.95 | positive regulation of sprouting angiogenesis | biological process | GO:1903672 | 41 | 7 | 20694 | 1406 |
Plk2,Itga5,Kdr,Il10,Akt3,Hmox1,Ptgs2 |
| 1.935e-02 | -3.95 | negative regulation of lipid localization | biological process | GO:1905953 | 41 | 7 | 20694 | 1406 |
Nfkbia,Thbs1,Ttc39b,Itgav,Ptpn2,Irs2,Nr1h3 |
| 1.935e-02 | -3.95 | homotypic cell-cell adhesion | biological process | GO:0034109 | 41 | 7 | 20694 | 1406 |
Slc7a11,Ubash3b,Plpp3,P2ry12,Plek,Stxbp1,Stxbp3 |
| 1.935e-02 | -3.95 | RNA phosphodiester bond hydrolysis, endonucleolytic | biological process | GO:0090502 | 41 | 7 | 20694 | 1406 |
Slfn8,Rcl1,Slfn9,Zc3h12a,Rrs1,Rnaset2a,Ago3 |
| 1.938e-02 | -3.94 | glucose homeostasis | biological process | GO:0042593 | 202 | 22 | 20694 | 1406 |
Sirt1,Hk3,Ptpn2,Slc16a1,Klf7,Ncoa5,Hk1,Icam1,Hk2,Igf1r,Vcam1,Stxbp3,Ptch1,Map2k1,Pdk3,Gk,Met,Stat3,Sesn3,Pde3b,Il6,Hif1a |
| 1.938e-02 | -3.94 | GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN | MSigDB lists | GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN | 143 | 19 | 15632 | 1249 |
Pgs1,Hlx,Larp1,Kdm4a,Phf11d,Tnfaip2,Phf11a,Tnip1,Acsl5,Gtpbp2,Phf11c,Brd2,Phf11b,Ccnj,Fubp1,Casp4,Phactr4,Tapbp,Tra2a |
| 1.949e-02 | -3.94 | Glycosaminoglycan metabolism | REACTOME pathways | R-MMU-1630316 | 113 | 17 | 8608 | 757 |
Ext1,Sdc4,B4galt4,Agrn,St3gal6,Ust,St3gal3,Dse,Abcc5,St3gal1,Papss2,Sdc1,Chst11,Gpc1,Sdc2,Vcan,Slc9a1 |
| 1.949e-02 | -3.94 | negative regulation of cell cycle phase transition | biological process | GO:1901988 | 145 | 17 | 20694 | 1406 |
Ccl12,Casp2,Pml,Cdkn1a,Ier3,Gpr132,Mdm2,Slfn1,Rgcc,Plk3,Ccnd1,Cdkn2d,Cenpe,Rbl1,Trip13,Dcun1d3,Atm |
| 1.949e-02 | -3.94 | copper ion binding | molecular function | GO:0005507 | 59 | 9 | 20217 | 1400 |
Prnp,Cutc,Cox17,Cp,Gpc1,Lacc1,Il1a,Mt1,Lox |
| 1.949e-02 | -3.94 | CCCNNGGGAR_OLF1_01 | MSigDB lists | CCCNNGGGAR_OLF1_01 | 295 | 34 | 15632 | 1249 |
Lhx2,H3f3b,Gcnt2,Tnip1,Ptafr,Ell2,Mtmr14,Vasp,Etv6,Vasn,Nfkbid,Rab10,Col11a2,Jarid2,Tnks1bp1,Rgs3,Pdgfc,Cyth3,Icam1,Kdm4a,Lrp8,Col18a1,Egr1,Bcor,Apba1,Abr,Dusp4,Mllt6,Fchsd2,Rhoq,Il4i1,Axl,Nfkbia,Flt1 |
| 1.954e-02 | -3.94 | Int_alpha | smart domains | SM00191 | 19 | 5 | 9567 | 823 |
Itgav,Itgal,Itga4,Itga9,Itga5 |
| 1.956e-02 | -3.93 | GO_VACUOLAR_MEMBRANE | MSigDB lists | GO_VACUOLAR_MEMBRANE | 542 | 57 | 15632 | 1249 |
Slc15a3,Rffl,Slc39a4,Cp,Rab21,H2-Q6,Acpp,Plekhf2,Ehd1,Cd164,Clcn5,Cd14,Gnb4,Myd88,Tab2,Cd74,Atp11a,Pml,Slc30a4,H2-Q7,Snx2,Vasn,H2-Aa,Antxr1,Rab10,Inpp5b,Atp6v1d,Irf7,Fzd5,Myo1b,Snx10,H2-Eb1,Acp2,Irak2,Ikbke,Mitd1,Slc29a3,Scyl2,Tlr3,H2-Ab1,Ap3b1,Irgm2,H2-Q4,Atp11b,Chmp4b,Fcgr1,Slc48a1,Pikfyve,Mmd,Cav1,Lnpep,Pmepa1,Ldlr,Rap2c,Clcn7,Tlr9,Dram1 |
| 1.964e-02 | -3.93 | REACTOME_SIGNALING_BY_WNT | MSigDB lists | REACTOME_SIGNALING_BY_WNT | 60 | 10 | 15632 | 1249 |
Ppp2r5a,Psme2,Ppp2r1b,Psma6,Psmb6,Psmb8,Psme1,Psmb10,Psmd10,Psmb9 |
| 1.965e-02 | -3.93 | negative regulation of protein complex assembly | biological process | GO:0031333 | 134 | 16 | 20694 | 1406 |
Src,Evl,Mefv,Lmo4,Crbn,Stxbp1,Xaf1,Birc2,Dbnl,Ptger4,Trim30a,Myadm,Pmepa1,Tmod3,Tlr2,Tmsb10 |
| 1.971e-02 | -3.93 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP | 153 | 20 | 15632 | 1249 |
Slco3a1,Il4ra,Irs2,Socs1,Ripk2,Tnfrsf14,Mob3c,Slc37a3,Jak2,Swap70,Mgat1,Ttc9c,Dusp6,Plod3,Stat4,Ccrl2,Treml2,Dhx58,Spint2,Rnf24 |
| 1.972e-02 | -3.93 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNG_KO_DN | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNG_KO_DN | 124 | 17 | 15632 | 1249 |
Psme2,Cp,Slamf9,Errfi1,Txnrd1,Rapgef5,Igsf9,Pik3r6,Slc2a1,Osm,Plekhg1,Irf8,Htr2a,Ube2f,Tmc3,Tlr3,Icam1 |
| 1.972e-02 | -3.93 | GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN | MSigDB lists | GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN | 124 | 17 | 15632 | 1249 |
Rhbdf2,Nrp2,Tifa,Piezo1,Degs2,Fam72a,Plk3,Trib1,Ccl22,Sphk1,Dmxl2,Jmjd6,Ciita,Myd88,Cd80,Stip1,Hsd17b7 |
| 1.974e-02 | -3.93 | RECEPTOR_TYR_KIN_III | prosite domains | PS00240 | 8 | 3 | 13278 | 1037 |
Flt1,Pdgfrb,Kdr |
| 1.974e-02 | -3.93 | DAD | prosite domains | PS51231 | 8 | 3 | 13278 | 1037 |
Daam1,Diaph2,Fmnl2 |
| 1.974e-02 | -3.93 | HSP70_1 | prosite domains | PS00297 | 8 | 3 | 13278 | 1037 |
Hspa2,Hspa1a,Hspa1b |
| 1.978e-02 | -3.92 | RAO_BOUND_BY_SALL4_ISOFORM_B | MSigDB lists | RAO_BOUND_BY_SALL4_ISOFORM_B | 466 | 50 | 15632 | 1249 |
Tcea1,Rcan1,Nsmaf,Arid5b,Cd55,Rtn1,Tmem26,Sh3bp4,Tbc1d13,Cd274,Cd38,Etv5,Ddx58,Cd180,Trim12c,Ier2,Pml,Rbpms,B3gnt5,Casp3,Arhgef3,Mtus1,Birc2,Fam162a,Tmem67,Asf1a,Itga9,Rcn1,Tmod3,Pla2g7,Rel,Lmo4,Tor3a,Dcun1d3,Ppp1r15b,Tle3,Phip,Znrf3,Nr1h3,Nck1,Tra2a,Vcan,Mllt6,Ift57,Gclm,Irgm2,Nat2,Rai14,Cited2,Rhof |
| 1.987e-02 | -3.92 | YAGI_AML_WITH_INV_16_TRANSLOCATION | MSigDB lists | YAGI_AML_WITH_INV_16_TRANSLOCATION | 380 | 42 | 15632 | 1249 |
Prnp,Ccnd2,Etv3,Lrp8,Mapkapk2,Hlx,Gbp2,Crim1,Traf5,Mapkbp1,Sdc4,Dock4,Klhl25,Arid5a,Timp1,Spryd7,Dpy19l1,Ezr,Dync1h1,Flt1,Nr4a1,Sele,S1pr2,Taf4b,Rbpms,Dusp2,Spry2,Nr3c1,Lyn,Nr4a3,Osgin2,Acvr1b,Ptprj,Egr3,Ppp2r2a,Cacna1d,Casp4,Gna15,Slc4a7,Pou2f2,Hap1,Spen |
| 1.991e-02 | -3.92 | cysteine-type endopeptidase inhibitor activity | molecular function | GO:0004869 | 69 | 10 | 20217 | 1400 |
Birc3,Tnfsf14,Serpinb9,Bcl2a1d,Cst7,Ctla2b,Prdx5,Serpina3g,Pttg1,Birc2 |
| 1.993e-02 | -3.92 | GO_PHOSPHOLIPID_BINDING | MSigDB lists | GO_PHOSPHOLIPID_BINDING | 327 | 37 | 15632 | 1249 |
Mitd1,Thbs1,Zcchc2,Ptafr,Nsmaf,Lpar1,Fcho2,Mppe1,Slc9a1,Wdfy1,Dgka,Rasgrp1,Snx2,Pla2g7,Rapgef2,Psd4,Snx10,Plek,Adap2,Plekha2,Plekha4,Myo1b,Sgk3,F10,Rnf34,Myo10,Apba1,Tulp3,Cyth3,Stap1,Pla2g4a,Kcnj2,Psd,Arhgap26,Plekha5,Axl,Itpr1 |
| 1.994e-02 | -3.92 | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | 163 | 21 | 15632 | 1249 |
Cysltr2,Zeb1,Dennd1b,Slc39a14,I830077J02Rik,Dock10,Syne2,Armcx6,Nfkb1,Plk2,Stau1,Zhx2,Nfil3,Ptger4,Dgkh,Tmtc2,Mafg,Serpinb9,Slc30a1,Spata5l1,Pik3cd |
| 1.995e-02 | -3.91 | filopodium membrane | cellular component | GO:0031527 | 16 | 4 | 20747 | 1409 |
Pdpn,Syne2,Itgav,Antxr1 |
| 1.995e-02 | -3.91 | MHC_I | pfam domains | PF00129 | 39 | 7 | 18711 | 1348 |
H2-Q7,H2-T10,H2-Q4,H2-T24,H2-M2,H2-T22,H2-Q6 |
| 1.996e-02 | -3.91 | epidermal cell differentiation | biological process | GO:0009913 | 168 | 19 | 20694 | 1406 |
Ptch1,Triobp,Casp3,Flnb,Clic4,Il1a,Jag1,Ptgs2,Palld,Slc4a7,Hdac1,Sec24b,Map2k1,Notch1,Sav1,Intu,Clic5,Pou3f1,Gfi1 |
| 1.997e-02 | -3.91 | macrophage activation involved in immune response | biological process | GO:0002281 | 16 | 4 | 20694 | 1406 |
Prkce,Cx3cr1,Syk,Ifnb1 |
| 1.997e-02 | -3.91 | positive regulation of cholesterol efflux | biological process | GO:0010875 | 16 | 4 | 20694 | 1406 |
Sirt1,Nr1h3,Ptch1,Nfkbia |
| 1.997e-02 | -3.91 | mast cell activation involved in immune response | biological process | GO:0002279 | 16 | 4 | 20694 | 1406 |
Milr1,Lyn,Nr4a3,Rasgrp1 |
| 1.997e-02 | -3.91 | positive regulation of synaptic transmission, GABAergic | biological process | GO:0032230 | 16 | 4 | 20694 | 1406 |
Nlgn2,Hap1,Adora2a,Prkce |
| 1.997e-02 | -3.91 | regulation of T cell chemotaxis | biological process | GO:0010819 | 16 | 4 | 20694 | 1406 |
Lgals9,Ccl5,Cxcl10,Tnfsf14 |
| 1.997e-02 | -3.91 | negative regulation of calcineurin-mediated signaling | biological process | GO:0106057 | 16 | 4 | 20694 | 1406 |
Dyrk2,Prnp,Atp2b4,Rcan1 |
| 1.997e-02 | -3.91 | response to progesterone | biological process | GO:0032570 | 16 | 4 | 20694 | 1406 |
Src,Nr1h3,Acod1,Cav1 |
| 1.997e-02 | -3.91 | negative regulation of calcineurin-NFAT signaling cascade | biological process | GO:0070885 | 16 | 4 | 20694 | 1406 |
Prnp,Dyrk2,Atp2b4,Rcan1 |
| 1.997e-02 | -3.91 | endothelial cell morphogenesis | biological process | GO:0001886 | 16 | 4 | 20694 | 1406 |
Plod3,Col18a1,Clic4,Met |
| 1.997e-02 | -3.91 | cellular response to leptin stimulus | biological process | GO:0044320 | 16 | 4 | 20694 | 1406 |
Nr4a3,Stat3,Sirt1,Pid1 |
| 1.997e-02 | -3.91 | regulation of cAMP-dependent protein kinase activity | biological process | GO:2000479 | 16 | 4 | 20694 | 1406 |
Sirt1,Rapgef2,Prkar2b,Atp2b4 |
| 1.997e-02 | -3.91 | positive regulation of leukocyte adhesion to vascular endothelial cell | biological process | GO:1904996 | 16 | 4 | 20694 | 1406 |
Tnf,Ptafr,Icam1,Itga4 |
| 1.997e-02 | -3.91 | mast cell degranulation | biological process | GO:0043303 | 16 | 4 | 20694 | 1406 |
Lyn,Milr1,Nr4a3,Rasgrp1 |
| 1.997e-02 | -3.91 | negative regulation of DNA damage response, signal transduction by p53 class mediator | biological process | GO:0043518 | 16 | 4 | 20694 | 1406 |
Sirt1,Psmd10,Cd74,Mdm2 |
| 1.997e-02 | -3.91 | regulation of cell proliferation involved in kidney development | biological process | GO:1901722 | 16 | 4 | 20694 | 1406 |
Myc,Pdgfb,Cflar,Egr1 |
| 1.997e-02 | -3.91 | sphingoid metabolic process | biological process | GO:0046519 | 16 | 4 | 20694 | 1406 |
Sphk1,Degs2,Plpp1,Asah2 |
| 1.997e-02 | -3.91 | cellular response to fluid shear stress | biological process | GO:0071498 | 16 | 4 | 20694 | 1406 |
Src,Ass1,Ptgs2,Klf2 |
| 1.999e-02 | -3.91 | BACH2_01 | MSigDB lists | BACH2_01 | 254 | 30 | 15632 | 1249 |
Col27a1,Cdkn1a,Gfi1,Itpkc,Dtx2,Mmp9,Pim1,Trib1,Akt3,Vasp,Hivep3,Csf3,Brd2,Eno2,Bmp2,Rnf34,Dusp14,Rhoc,Csrnp1,Prdm1,Slc39a13,Dennd1b,S1pr2,Ass1,Gadd45b,Map3k6,Nr4a1,Dync1h1,Eno1,Acpp |
| 1.999e-02 | -3.91 | GO_MUSCLE_ORGAN_DEVELOPMENT | MSigDB lists | GO_MUSCLE_ORGAN_DEVELOPMENT | 254 | 30 | 15632 | 1249 |
Egr2,Tagln,Ass1,Homer1,Fos,Serp1,Sgcb,Bmp2,Notch1,Cd164,Atf3,Hlx,Lif,Egr1,Nupr1,Plagl1,Sap30,Bcl9,Btg2,Flnb,Sirt1,Hivep3,Maff,Fzd1,Cav1,Igsf8,Cflar,Egr3,Cxcl10,Arid5b |
| 1.999e-02 | -3.91 | GO_CYTOPLASMIC_REGION | MSigDB lists | GO_CYTOPLASMIC_REGION | 254 | 30 | 15632 | 1249 |
Ap3m2,Wdr43,Tnfaip2,Spire1,Uchl1,Ptk2,Hap1,Flnb,Rab10,Nos2,Cav1,Myadm,Clic5,Myo10,Daxx,Agtrap,Hif1a,Ap3b1,Sele,Dbnl,Rai14,Rab21,Gpsm2,Trip10,Slc2a1,Cd302,Traf2,Phldb1,Gypc,Ezr |
| 1.999e-02 | -3.91 | GRB2 events in EGFR signaling | REACTOME pathways | R-MMU-179812 | 213 | 28 | 8608 | 757 |
Ppp2r1b,Jak2,Map2k1,Ksr1,Il2rg,Pdgfrb,Angpt1,Psme2b,Src,Ppp2r5a,Irs2,Spred1,Kitl,Pdgfb,Psme1,Dusp5,Psmb6,Dusp6,Rapgef2,Rasgrp1,Psmb9,Psmd10,Psme2,Psma6,Psmb10,Ptk2,Met,Psmb8 |
| 1.999e-02 | -3.91 | RAF/MAP kinase cascade | REACTOME pathways | R-MMU-5673001 | 213 | 28 | 8608 | 757 |
Psmb6,Dusp6,Psme1,Dusp5,Rasgrp1,Psmb9,Rapgef2,Psme2,Psma6,Psmd10,Ptk2,Met,Psmb8,Psmb10,Jak2,Map2k1,Ppp2r1b,Pdgfrb,Ksr1,Il2rg,Src,Ppp2r5a,Irs2,Angpt1,Psme2b,Pdgfb,Spred1,Kitl |
| 1.999e-02 | -3.91 | SOS-mediated signalling | REACTOME pathways | R-MMU-112412 | 213 | 28 | 8608 | 757 |
Pdgfb,Kitl,Spred1,Ppp2r5a,Irs2,Src,Psme2b,Angpt1,Pdgfrb,Il2rg,Ksr1,Map2k1,Jak2,Ppp2r1b,Psmb8,Met,Ptk2,Psmb10,Psma6,Psme2,Psmd10,Psmb9,Rasgrp1,Rapgef2,Dusp6,Psmb6,Dusp5,Psme1 |
| 1.999e-02 | -3.91 | SHC1 events in EGFR signaling | REACTOME pathways | R-MMU-180336 | 213 | 28 | 8608 | 757 |
Angpt1,Psme2b,Src,Irs2,Ppp2r5a,Spred1,Kitl,Pdgfb,Ppp2r1b,Jak2,Map2k1,Ksr1,Il2rg,Pdgfrb,Psmd10,Psme2,Psma6,Psmb10,Met,Ptk2,Psmb8,Psme1,Dusp5,Psmb6,Dusp6,Rapgef2,Rasgrp1,Psmb9 |
| 1.999e-02 | -3.91 | Signalling to p38 via RIT and RIN | REACTOME pathways | R-MMU-187706 | 213 | 28 | 8608 | 757 |
Rasgrp1,Psmb9,Rapgef2,Psmb6,Dusp6,Psme1,Dusp5,Met,Ptk2,Psmb8,Psmb10,Psme2,Psma6,Psmd10,Pdgfrb,Ksr1,Il2rg,Jak2,Map2k1,Ppp2r1b,Pdgfb,Spred1,Kitl,Src,Irs2,Ppp2r5a,Angpt1,Psme2b |
| 2.002e-02 | -3.91 | PASINI_SUZ12_TARGETS_UP | MSigDB lists | PASINI_SUZ12_TARGETS_UP | 96 | 14 | 15632 | 1249 |
Slc39a4,Htra1,AA467197,Cdyl2,Ass1,Plekha4,Mov10,Klf2,Tet2,Zc3hav1,Fabp3,Agtrap,Trib3,Upp1 |
| 2.002e-02 | -3.91 | HOOI_ST7_TARGETS_DN | MSigDB lists | HOOI_ST7_TARGETS_DN | 96 | 14 | 15632 | 1249 |
Naa25,Nfkbiz,Kdr,Bambi,Itpr1,Eno2,Pdk3,Ccng2,Rin2,Pla2g7,Rbpms,Mmp13,Bbx,Dennd1b |
| 2.002e-02 | -3.91 | AAACCAC_MIR140 | MSigDB lists | AAACCAC_MIR140 | 96 | 14 | 15632 | 1249 |
Acvr1,Rnf19a,Snx2,Mmd,Nr3c1,Bcl9,Mgat1,Ehd1,Tshz1,Abcc4,Gys1,Etv3,Ubash3b,Map3k8 |
| 2.004e-02 | -3.91 | response to organophosphorus | biological process | GO:0046683 | 91 | 12 | 20694 | 1406 |
Il1b,Casp1,Ezr,Junb,Rapgef2,Ahr,Lpar1,P2ry12,Jun,Sell,Itpr1,Stat1 |
| 2.007e-02 | -3.91 | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | MSigDB lists | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | 173 | 22 | 15632 | 1249 |
Htr2a,Gng11,Gnb4,Htr2b,Xcr1,Gng12,Gng4,Dgkh,Ptafr,Fpr2,Lpar1,Prkce,Gpr132,Edn1,Prokr1,Cysltr2,Gpr68,Rasgrp1,Dgka,Ednrb,P2ry2,Gna15 |
| 2.007e-02 | -3.91 | GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_DN | MSigDB lists | GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_DN | 173 | 22 | 15632 | 1249 |
Apobec3,Msr1,Gpsm2,D1Ertd622e,Ggct,Pttg1,Prdx1,Extl2,Plau,Cd14,P4ha1,Lap3,Atp6v1d,Bst1,Hk2,Ifi35,Dram1,Ms4a6d,Frmd4a,Adrb2,Gng12,Acp2 |
| 2.007e-02 | -3.91 | GSE26351_WNT_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_DN | MSigDB lists | GSE26351_WNT_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_DN | 173 | 22 | 15632 | 1249 |
1600014C10Rik,Slfn9,Hk3,Zfp513,Mmp9,Phip,Cdk5r1,Ttc39b,Irs2,Cdc42ep4,Ddit4,Slfn8,Reps1,Prkce,Hivep3,Ythdf1,Pou2f2,Gsdmd,Cst7,Ikbkg,Lap3,Atp6v1d |
| 2.011e-02 | -3.91 | GO_HEART_DEVELOPMENT | MSigDB lists | GO_HEART_DEVELOPMENT | 434 | 47 | 15632 | 1249 |
Bcor,Sgcb,Jun,Cited2,Flrt3,Cox17,Ift57,Edn1,Ptk2,Rpgrip1l,Notch2,Adam19,Sema3c,Lmo4,Adap2,Ptch1,Atm,Jag1,Slc9a1,Tab2,Calcrl,Hif1a,Jmjd6,Prdm1,Hhex,Notch1,Sav1,Bmp2,Gys1,Mdm2,Acvr1,Mecp2,Casp3,Setdb2,Lox,Crkl,Kdm6b,Sec24b,Htr2b,Flrt2,Hopx,Map2k1,Pdgfrb,Gja1,Mmp13,Fzd1,Pdgfb |
| 2.012e-02 | -3.91 | HSIAO_HOUSEKEEPING_GENES | MSigDB lists | HSIAO_HOUSEKEEPING_GENES | 359 | 40 | 15632 | 1249 |
Prdx1,Cd34,Cd164,Fas,Psme1,H2-Q7,Cd74,Ccnd2,Stat3,Hdac1,Psd,Rbpms,H2-Q4,Ezr,Dusp1,Nfkbia,Sqstm1,H2-Q6,Eno1,Actb,Arf4,Tax1bp1,Esd,H3f3b,Pgk1,Tcea1,H2-Ab1,Psmb6,Ldha,Pim1,Btg2,Isg20,Scn1b,Zfp36,Htra1,Wars,Txn1,Junb,Eif4g2,Brd2 |
| 2.012e-02 | -3.91 | GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_DN | 183 | 23 | 15632 | 1249 |
Phgdh,C1ra,Usp53,Gadd45b,Dusp1,Batf,Rnd3,Pim3,Tnfaip3,Etv5,Prrg4,Agtrap,Cd69,Junb,Osm,Gem,Adap2,Fosb,Zc3h12c,Ppp1r15a,Rgs1,Bambi,Cacna1d |
| 2.012e-02 | -3.91 | GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_DN | MSigDB lists | GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_DN | 183 | 23 | 15632 | 1249 |
Cyth3,Sass6,Sell,Slc30a4,Itga4,Slc31a1,Mcoln2,Rhoh,Klf7,Mapkbp1,Cldnd1,Idi1,Psat1,Plac8,Txn1,Map4k4,Cpd,Tyk2,Cnn3,Plscr1,Peli1,Trip13,Slc7a5 |
| 2.012e-02 | -3.91 | GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_UP | MSigDB lists | GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_UP | 183 | 23 | 15632 | 1249 |
Gadd45g,Ythdf1,Atp13a1,Ifrd1,Ccdc86,Slc44a1,Sat1,Tiparp,Ptpn2,Itpr1,Ahr,Cd14,Cd34,Atp11a,Hat1,Pla2g7,Wars,Lcn2,Snx10,Gng12,Kitl,Il13ra1,C3 |
| 2.012e-02 | -3.91 | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP | MSigDB lists | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP | 183 | 23 | 15632 | 1249 |
Sema4a,Hivep3,Rapgef2,Tyk2,Stx6,Med13,Alas1,Ampd3,Piezo1,Atp6v1d,Ppp1r15b,Tuba4a,Daxx,Tle3,Il15,Zbtb5,Phactr4,Ccng2,Rhoq,Ifit2,Spn,Syk,Bcl2l11 |
| 2.012e-02 | -3.91 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN | 183 | 23 | 15632 | 1249 |
Prpf4,Plagl2,Dusp14,Rnf34,Sdc4,Ahsa1,Ier3,Etnk1,Tpi1,Gng4,Uchl1,Cox17,Eef1e1,Irf4,Ccdc86,Phlpp2,Cish,Tgs1,Higd1a,Cacybp,Slc2a1,P4ha2,Ccne1 |
| 2.012e-02 | -3.91 | GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_DN | MSigDB lists | GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_DN | 183 | 23 | 15632 | 1249 |
Eno1,Srm,Aoah,Katna1,Edn1,Gclm,Arl4a,Il1a,Evl,Plk3,Ripk3,Sema3c,Dcun1d3,Mmp13,Hivep3,Bst1,Inhba,Ell2,Tfec,Ppp2r2a,Plekhn1,Fam162a,Ikbke |
| 2.012e-02 | -3.91 | GSE27786_LIN_NEG_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_CD8_TCELL_UP | 183 | 23 | 15632 | 1249 |
Rbbp8,Dmwd,Cyfip1,Hk1,Dach1,Mthfd1l,Phactr4,Egln3,Scarf1,Hk2,Chst11,Lztfl1,Ogfrl1,St7,Pik3cd,Dnajb4,Ak4,Rcan1,Trim13,Pml,Magohb,Hlx,Cutc |
| 2.012e-02 | -3.91 | GSE12198_CTRL_VS_LOW_IL2_STIM_NK_CELL_UP | MSigDB lists | GSE12198_CTRL_VS_LOW_IL2_STIM_NK_CELL_UP | 183 | 23 | 15632 | 1249 |
Isg20,Sat1,Katna1,Ap3b1,Errfi1,Tapbp,Tmem176a,Plac8,P4ha2,Klf3,Syk,Gypc,Tax1bp1,Kdr,Crim1,Cpeb4,Tlr6,Egr1,Mthfr,Acvr1b,Icam1,Arl4a,Xrn1 |
| 2.012e-02 | -3.91 | GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP | MSigDB lists | GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP | 183 | 23 | 15632 | 1249 |
Vps54,Ppm1k,Tlr1,Xaf1,Oas2,Usp12,Trim56,Filip1l,Azi2,Rcn1,Cflar,Ifnar1,Zyx,Gpr18,Ubtd2,1110038F14Rik,Tapbp,Cept1,Kdm5b,Bcor,St3gal6,Extl2,Rgs3 |
| 2.014e-02 | -3.90 | Mitotic G1-G1/S phases | REACTOME pathways | R-MMU-453279 | 131 | 19 | 8608 | 757 |
Psma6,Psme2,Psme2b,Ppp2r2a,Psmd10,Ccne1,Psmb8,Mcm6,Cdkn1a,Hdac1,Psmb10,Psmb6,Ccnd1,Psme1,Ppp2r1b,Cdkn2d,Psmb9,Mcm10,Rbl1 |
| 2.015e-02 | -3.90 | Fcgamma receptor (FCGR) dependent phagocytosis | REACTOME pathways | R-MMU-2029480 | 55 | 10 | 8608 | 757 |
Fcgr2b,Nck1,Prkce,Actb,Fcgr1,Cyfip1,Ptk2,Syk,Fcgr4,Myo10 |
| 2.019e-02 | -3.90 | GO_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_PROTEIN_KINASE_ACTIVITY | 598 | 62 | 15632 | 1249 |
Jak2,Kdr,Fam20c,Igf1r,Vrk2,Cdkn1a,Ptk2,Pim2,Dyrk2,Acvr1b,Trib1,Map2k4,Lyn,Akt3,Ksr1,Mmd,Met,Pdk3,Atm,Sik3,Pim3,Mark2,Mapkapk2,Nek6,Cdk5r1,Prkce,Flt1,Eif2ak2,Map3k6,Sqstm1,Syk,Ccl12,Prkx,Irak2,Ikbke,Scyl2,Ripk2,Pim1,Map3k8,Nrp2,Tyk2,Map4k4,Ccl5,Plk2,Pdgfrb,Map2k1,Sgk3,Ripk3,Crim1,Irak3,Hck,Plk3,Fgr,Tlk2,Ccnd1,Acvr1,Acvrl1,Mlkl,Stk40,Src,Stat5a,Axl |
| 2.024e-02 | -3.90 | GO_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY | MSigDB lists | GO_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY | 69 | 11 | 15632 | 1249 |
Pik3r5,Atm,Pik3r6,Pdgfrb,Cd86,Pdgfb,Tlr9,Pik3cd,Irs2,Kitl,Cd80 |
| 2.024e-02 | -3.90 | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | MSigDB lists | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | 69 | 11 | 15632 | 1249 |
Plaur,Snn,Pou2f2,Triobp,Ppfia3,Pdgfb,Rab11fip1,Phlda1,Col11a2,Pik3cd,Dusp1 |
| 2.024e-02 | -3.90 | GCAAGGA_MIR502 | MSigDB lists | GCAAGGA_MIR502 | 69 | 11 | 15632 | 1249 |
Rnf31,Eif4g2,Mier3,Map2k4,Kitl,Akt3,Rilpl1,Nfxl1,Casp2,Mid1,Dio2 |
| 2.026e-02 | -3.90 | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | REACTOME pathways | R-MMU-1234176 | 63 | 11 | 8608 | 757 |
Psme2,Psmb6,Psma6,Psme1,Psmd10,Egln3,Psme2b,Psmb8,Psmb9,Psmb10,Hif1a |
| 2.026e-02 | -3.90 | mouse chr4 E2|4 78.67 cM | chromosome location | mouse chr4 E2|4 78.67 cM | 4 | 2 | 24173 | 1464 |
Mthfr,Agtrap |
| 2.026e-02 | -3.90 | mouse chr11 B1.2|11 | chromosome location | mouse chr11 B1.2|11 | 4 | 2 | 24173 | 1464 |
Tgtp2,Gm12185 |
| 2.027e-02 | -3.90 | RET signaling | REACTOME pathways | R-MMU-8853659 | 232 | 30 | 8608 | 757 |
Kitl,Pdlim7,Spred1,Pdgfb,Psme2b,Angpt1,Irs2,Ppp2r5a,Src,Il2rg,Ksr1,Pdgfrb,Ppp2r1b,Map2k1,Jak2,Psmb10,Psmb8,Ptk2,Met,Psmd10,Psma6,Psme2,Pik3cd,Rapgef2,Psmb9,Rasgrp1,Dusp5,Psme1,Dusp6,Psmb6 |
| 2.029e-02 | -3.90 | STAT family protein binding | molecular function | GO:0097677 | 9 | 3 | 20217 | 1400 |
Parp9,Ptpn2,Dtx3l |
| 2.029e-02 | -3.90 | Tat protein binding | molecular function | GO:0030957 | 9 | 3 | 20217 | 1400 |
Actb,Dnaja1,Mdfic |
| 2.029e-02 | -3.90 | immunoglobulin receptor binding | molecular function | GO:0034987 | 9 | 3 | 20217 | 1400 |
Fgr,Tarm1,Clec4d |
| 2.029e-02 | -3.90 | angiotensin receptor binding | molecular function | GO:0031701 | 9 | 3 | 20217 | 1400 |
Ednrb,Tyk2,Jak2 |
| 2.029e-02 | -3.90 | phospholipase activator activity | molecular function | GO:0016004 | 9 | 3 | 20217 | 1400 |
Nsmaf,Casp3,Ccl5 |
| 2.029e-02 | -3.90 | oligopeptide transmembrane transporter activity | molecular function | GO:0035673 | 9 | 3 | 20217 | 1400 |
Slco3a1,Slc15a3,Abcc1 |
| 2.029e-02 | -3.90 | BROWNE_HCMV_INFECTION_24HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_UP | 134 | 18 | 15632 | 1249 |
Zhx2,Keap1,Etv5,Cxcl1,Cd83,St7,Nr4a3,Ak4,Icam1,Lrp8,Rasgrp1,Dtnb,Trip10,Fzd5,Gpr18,N4bp1,Plek,Nfkbia |
| 2.030e-02 | -3.90 | Glycolysis and Gluconeogenesis | WikiPathways | WP157 | 50 | 11 | 4813 | 540 |
Pfkl,Pcx,Slc2a1,Ldha,Hk3,Pgk1,Hk2,Eno2,Eno1,Hk1,Tpi1 |
| 2.032e-02 | -3.90 | Extracellular matrix organization | REACTOME pathways | R-MMU-1474244 | 270 | 34 | 8608 | 757 |
Dst,Timp1,Plod3,Serpine1,Mmp14,Agrn,Itga5,Itgal,Sdc2,Plod2,Col18a1,Itga4,Lox,Vcan,Tnc,Bmp2,Sdc1,F11r,Vcam1,P4ha2,Mmp13,Itgb8,Col11a2,Sdc4,Itgav,Kdr,Mmp9,Pdgfb,Thbs1,Col4a2,P4ha1,Icam1,Col27a1,Itga9 |
| 2.033e-02 | -3.90 | Antigen processing: Ubiquitination & Proteasome degradation | REACTOME pathways | R-MMU-983168 | 149 | 21 | 8608 | 757 |
Rnf19b,Herc6,Psmb8,Znrf1,Psmb10,Psma6,Uba7,Psme2,Psme2b,Fbxo4,Psmd10,Rnf19a,Psmb9,Lnpep,Spsb1,Trim21,Psmb6,Rnf114,Trim36,Psme1,Dtx3l |
| 2.033e-02 | -3.90 | GO_MUSCLE_STRUCTURE_DEVELOPMENT | MSigDB lists | GO_MUSCLE_STRUCTURE_DEVELOPMENT | 402 | 44 | 15632 | 1249 |
Fos,Homer1,Serp1,Ass1,Tagln,Ifrd1,Acvr1,Egr2,Sdc1,Plagl1,Hlx,Atf3,Egr1,Nupr1,Lif,Cd164,Notch1,Sgcb,Hinfp,Bmp2,Cav1,Igsf8,Pdgfrb,Ednrb,Jag1,Sirt1,Hivep3,Fzd1,Maff,Ppp2r3a,Btg2,Slc9a1,Sap30,Bcl9,Flnb,Arid5b,Cxcl10,Sema4c,Egr3,Kdm6b,Uchl1,Tmod3,Cflar,Asf1a |
| 2.033e-02 | -3.90 | LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT | MSigDB lists | LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT | 87 | 13 | 15632 | 1249 |
Il1rn,Crim1,Mxd1,Egr3,Dusp5,Tmod3,Ptgs2,Slco3a1,Rab11fip1,Tlr1,AA467197,B4galt4,Lcn2 |
| 2.033e-02 | -3.90 | BRUINS_UVC_RESPONSE_MIDDLE | MSigDB lists | BRUINS_UVC_RESPONSE_MIDDLE | 87 | 13 | 15632 | 1249 |
Ptk2,Icam1,Trim13,Rbm43,Gpr84,Caml,Sap30,Btg2,Isg20,Pnp2,Chst11,Zscan29,Slc25a12 |
| 2.039e-02 | -3.89 | carbohydrate homeostasis | biological process | GO:0033500 | 203 | 22 | 20694 | 1406 |
Igf1r,Hk2,Stxbp3,Ptch1,Vcam1,Slc16a1,Klf7,Ncoa5,Hk1,Icam1,Ptpn2,Sirt1,Hk3,Il6,Pde3b,Hif1a,Sesn3,Gk,Met,Stat3,Pdk3,Map2k1 |
| 2.041e-02 | -3.89 | TNFR_NGFR_1 | prosite domains | PS00652 | 21 | 5 | 13278 | 1037 |
Tnfrsf8,Cd40,Tnfrsf14,Tnfrsf1b,Fas |
| 2.041e-02 | -3.89 | PDEASE_I_1 | prosite domains | PS00126 | 21 | 5 | 13278 | 1037 |
Pde7b,Pde1b,Pde3b,Pde5a,Pde4b |
| 2.041e-02 | -3.89 | FE2OG_OXY | prosite domains | PS51471 | 21 | 5 | 13278 | 1037 |
Plod2,Plod3,P4ha1,Egln3,P4ha2 |
| 2.041e-02 | -3.89 | PDEASE_I_2 | prosite domains | PS51845 | 21 | 5 | 13278 | 1037 |
Pde5a,Pde4b,Pde3b,Pde1b,Pde7b |
| 2.043e-02 | -3.89 | SANA_RESPONSE_TO_IFNG_DN | MSigDB lists | SANA_RESPONSE_TO_IFNG_DN | 78 | 12 | 15632 | 1249 |
Antxr1,Pim3,Prdx1,Cd34,Nqo1,Rhoc,Inhba,Gja1,Tuba4a,Eif4g2,Tpx2,Odc1 |
| 2.043e-02 | -3.89 | PID_MET_PATHWAY | MSigDB lists | PID_MET_PATHWAY | 78 | 12 | 15632 | 1249 |
Map2k1,Jun,Ptpn2,Map2k4,Egr1,Ptk2,Src,Ptprj,Nck1,Crkl,Met,Rin2 |
| 2.047e-02 | -3.89 | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | MSigDB lists | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | 115 | 16 | 15632 | 1249 |
Stat5a,Src,Nr4a1,Map2k1,Pde1b,Prkce,Akt3,Stat3,Spry2,Phlpp1,Mdm2,Rictor,Stat1,Trib3,Prkar2b,Cdkn1a |
| 2.047e-02 | -3.89 | GSE32901_NAIVE_VS_TH1_CD4_TCELL_UP | MSigDB lists | GSE32901_NAIVE_VS_TH1_CD4_TCELL_UP | 115 | 16 | 15632 | 1249 |
Parp11,Adrb2,Rtp4,Slco3a1,Itga4,Vegfc,Hk3,Olfml3,Irak3,Pde3b,Thbs1,Flrt2,Klf2,Vezt,Abtb2,Parp14 |
| 2.047e-02 | -3.89 | GO_POSITIVE_REGULATION_OF_ENDOCYTOSIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_ENDOCYTOSIS | 115 | 16 | 15632 | 1249 |
Sele,Stap1,Rab21,Serpine1,Cav1,Itgav,Ccl12,Syk,Tnf,Axl,Angpt1,Il1b,Cd14,Scyl2,C3,Abr |
| 2.047e-02 | -3.89 | GO_INOSITOL_LIPID_MEDIATED_SIGNALING | MSigDB lists | GO_INOSITOL_LIPID_MEDIATED_SIGNALING | 115 | 16 | 15632 | 1249 |
Pik3cd,Irs2,Ptafr,Htr2b,Igf1r,Kitl,Cd80,Htr2a,Pdgfrb,Cd86,Mov10,Pik3r5,Ezr,Rictor,Pdgfb,Edn1 |
| 2.050e-02 | -3.89 | Phospholipase D signaling pathway | KEGG pathways | mmu04072 | 146 | 21 | 7931 | 713 |
Syk,Pdgfrb,Pik3r5,Pik3cd,Map2k1,Lpar1,Dgkh,Plpp3,Pik3r6,Akt3,Ralgds,Pdgfc,Plpp1,Pdgfb,Dgka,Cyth3,Pla2g4a,Agpat4,Sphk1,Kitl,Rras2 |
| 2.050e-02 | -3.89 | Phospholipase D signaling pathway | KEGG pathways | ko04072 | 146 | 21 | 7931 | 713 |
Plpp3,Dgkh,Lpar1,Map2k1,Pik3cd,Pik3r5,Pdgfrb,Syk,Rras2,Pla2g4a,Sphk1,Kitl,Agpat4,Cyth3,Plpp1,Dgka,Pdgfb,Pdgfc,Pik3r6,Ralgds,Akt3 |
| 2.055e-02 | -3.88 | PR_Q2 | MSigDB lists | PR_Q2 | 234 | 28 | 15632 | 1249 |
Klf3,Fchsd2,Cxcl14,Palld,Pigv,Il1a,Rgs3,Notch1,Sesn3,Jdp2,Itgal,Bcl9,Caml,Ppp2r3a,Sh3bp4,Dtx2,Cpeb4,Hmgcs1,Dgkh,Cdc42ep4,Lox,Nr4a3,Cacnb3,Rcn1,Snapc1,Nfil3,Ppp2r2a,Tagap |
| 2.065e-02 | -3.88 | response to arsenic-containing substance | biological process | GO:0046685 | 24 | 5 | 20694 | 1406 |
Gclc,Hmox1,Daxx,Zc3h12a,Nr3c1 |
| 2.065e-02 | -3.88 | response to lipoprotein particle | biological process | GO:0055094 | 24 | 5 | 20694 | 1406 |
Ldlr,Tlr6,Hmgcs1,Myd88,Syk |
| 2.065e-02 | -3.88 | positive regulation of hormone metabolic process | biological process | GO:0032352 | 24 | 5 | 20694 | 1406 |
Igf1r,Tnf,Egr1,Il1b,Hif1a |
| 2.065e-02 | -3.88 | positive regulation of monooxygenase activity | biological process | GO:0032770 | 24 | 5 | 20694 | 1406 |
Il1b,Tnf,Htr2b,Gch1,Nod1 |
| 2.065e-02 | -3.88 | positive regulation of interleukin-4 production | biological process | GO:0032753 | 24 | 5 | 20694 | 1406 |
Syk,Irf4,Tnfsf4,Icosl,Nlrp3 |
| 2.065e-02 | -3.88 | negative regulation of histone methylation | biological process | GO:0031061 | 24 | 5 | 20694 | 1406 |
Kdm4a,Mllt6,Jarid2,Bcor,Sirt1 |
| 2.065e-02 | -3.88 | response to monoamine | biological process | GO:0071867 | 24 | 5 | 20694 | 1406 |
Nr4a3,Htr2b,Atp2b4,Slc9a1,Pde4b |
| 2.065e-02 | -3.88 | T cell lineage commitment | biological process | GO:0002360 | 24 | 5 | 20694 | 1406 |
Il6,Spn,Irf4,Stat3,Batf |
| 2.065e-02 | -3.88 | gluconeogenesis | biological process | GO:0006094 | 24 | 5 | 20694 | 1406 |
Gpd2,Tpi1,Pcx,Atf3,Pgk1 |
| 2.065e-02 | -3.88 | regulation of superoxide anion generation | biological process | GO:0032928 | 24 | 5 | 20694 | 1406 |
Fpr2,Cxcl1,Syk,Il18,Acp5 |
| 2.065e-02 | -3.88 | positive regulation of calcium ion import | biological process | GO:0090280 | 24 | 5 | 20694 | 1406 |
Pdgfrb,Ccl12,Serpine1,Adrb2,Pdgfb |
| 2.065e-02 | -3.88 | regulation of mitochondrial fission | biological process | GO:0090140 | 24 | 5 | 20694 | 1406 |
Kdr,Stat2,Bnip3,Mul1,Ddhd1 |
| 2.071e-02 | -3.88 | - | gene3d domains | 1.10.10.1880 | 3 | 2 | 8819 | 755 |
Marf1,Tdrd7 |
| 2.072e-02 | -3.88 | GO_AMEBOIDAL_TYPE_CELL_MIGRATION | MSigDB lists | GO_AMEBOIDAL_TYPE_CELL_MIGRATION | 144 | 19 | 15632 | 1249 |
Prkx,Kdr,Kitl,Htr2b,Ptk2,Egr3,Itga4,Sema4c,Pml,Stat1,Hif1a,Sema4a,Arid5b,Acvr1,Phactr4,Syne2,Nr4a1,Ednrb,Sema3c |
| 2.075e-02 | -3.88 | TYRKINASE | prints domains | PR00109 | 97 | 12 | 5821 | 374 |
Axl,Hck,Lyn,Src,Jak2,Ptk2,Fgr,Syk,Nek6,Tyk2,Met,Igf1r |
| 2.079e-02 | -3.87 | TEF_Q6 | MSigDB lists | TEF_Q6 | 224 | 27 | 15632 | 1249 |
Pbx1,Prdx1,Tle3,Olfml3,Etv5,Rgs3,Spred1,Crim1,Slco3a1,Arg2,Usp18,Rhoq,Egr2,D1Ertd622e,Spry2,Ppfia3,Ccnd1,Hivep2,Dock4,Cacna1d,Hcar2,Igf1r,Lox,Leng9,Hivep3,Pde4b,Cdyl |
| 2.085e-02 | -3.87 | GNF2_MYD88 | MSigDB lists | GNF2_MYD88 | 52 | 9 | 15632 | 1249 |
Lyn,Psmb10,Sell,Rnaset2a,Tnfrsf1b,Casp1,Rnaset2b,Hcls1,Myd88 |
| 2.085e-02 | -3.87 | GO_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS | MSigDB lists | GO_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS | 52 | 9 | 15632 | 1249 |
Pde4b,Cnp,Calcrl,Pde1b,Pde3b,Pde7b,Pde5a,Adora2a,Htr2b |
| 2.085e-02 | -3.87 | GO_EXECUTION_PHASE_OF_APOPTOSIS | MSigDB lists | GO_EXECUTION_PHASE_OF_APOPTOSIS | 52 | 9 | 15632 | 1249 |
Casp7,Ptk2,Xkr8,Birc2,Casp8,Casp3,Cflar,Dnase1l3,Casp2 |
| 2.085e-02 | -3.87 | HALLMARK_TGF_BETA_SIGNALING | MSigDB lists | HALLMARK_TGF_BETA_SIGNALING | 52 | 9 | 15632 | 1249 |
Serpine1,Ppp1r15a,Ltbp2,Junb,Pmepa1,Acvr1,Hdac1,Thbs1,Bmp2 |
| 2.085e-02 | -3.87 | AR_03 | MSigDB lists | AR_03 | 52 | 9 | 15632 | 1249 |
Cxcl14,Slc9a1,Rcn1,Sdc1,Dnajb4,Bcl6,Cpeb4,Slc7a8,Smox |
| 2.087e-02 | -3.87 | B302_SPRY | prosite domains | PS50188 | 80 | 12 | 13278 | 1037 |
Spsb1,Trim30d,Mid1,Trim26,Trim21,Trim12c,Trim30a,Trim34a,Trim14,Trim36,Rnf135,Spryd7 |
| 2.091e-02 | -3.87 | DUF3454 | smart domains | SM01334 | 3 | 2 | 9567 | 823 |
Notch2,Notch1 |
| 2.091e-02 | -3.87 | ZnF_NFX | smart domains | SM00438 | 3 | 2 | 9567 | 823 |
Znfx1,Nfxl1 |
| 2.097e-02 | -3.86 | Colorectal cancer | KEGG pathways | mmu05210 | 62 | 11 | 7931 | 713 |
Ccnd1,Rac3,Myc,Map2k1,Pik3cd,Casp3,Cycs,Fos,Ralgds,Akt3,Jun |
| 2.097e-02 | -3.86 | Colorectal cancer | KEGG pathways | ko05210 | 62 | 11 | 7931 | 713 |
Jun,Pik3cd,Myc,Map2k1,Casp3,Cycs,Ccnd1,Rac3,Akt3,Ralgds,Fos |
| 2.100e-02 | -3.86 | KUMAMOTO_RESPONSE_TO_NUTLIN_3A_UP | MSigDB lists | KUMAMOTO_RESPONSE_TO_NUTLIN_3A_UP | 8 | 3 | 15632 | 1249 |
Gdf15,Btg2,Mdm2 |
| 2.100e-02 | -3.86 | MIKKELSEN_PLURIPOTENT_STATE_DN | MSigDB lists | MIKKELSEN_PLURIPOTENT_STATE_DN | 8 | 3 | 15632 | 1249 |
Casp8,Ccnd2,Jak2 |
| 2.100e-02 | -3.86 | OXFORD_RALB_TARGETS_DN | MSigDB lists | OXFORD_RALB_TARGETS_DN | 8 | 3 | 15632 | 1249 |
Dusp6,Pml,Usp18 |
| 2.100e-02 | -3.86 | FUJIWARA_PARK2_IN_LIVER_CANCER_UP | MSigDB lists | FUJIWARA_PARK2_IN_LIVER_CANCER_UP | 8 | 3 | 15632 | 1249 |
Ccne1,Il1rn,Golga3 |
| 2.100e-02 | -3.86 | GO_IGG_BINDING | MSigDB lists | GO_IGG_BINDING | 8 | 3 | 15632 | 1249 |
Fcgr1,Fcgr2b,Fcgr4 |
| 2.100e-02 | -3.86 | BRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS | MSigDB lists | BRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS | 8 | 3 | 15632 | 1249 |
Notch1,Jag1,Notch2 |
| 2.100e-02 | -3.86 | BOYLAN_MULTIPLE_MYELOMA_PCA1_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA1_DN | 8 | 3 | 15632 | 1249 |
Lhx2,Plk2,Cnn3 |
| 2.100e-02 | -3.86 | DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_DN | MSigDB lists | DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_DN | 8 | 3 | 15632 | 1249 |
Serpine1,Dusp5,Actb |
| 2.100e-02 | -3.86 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_16 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_16 | 8 | 3 | 15632 | 1249 |
Ext1,Myc,Tcea1 |
| 2.100e-02 | -3.86 | GROSS_HYPOXIA_VIA_HIF1A_ONLY | MSigDB lists | GROSS_HYPOXIA_VIA_HIF1A_ONLY | 8 | 3 | 15632 | 1249 |
Maff,Ccng2,Cited2 |
| 2.100e-02 | -3.86 | GO_REGULATION_OF_NLRP3_INFLAMMASOME_COMPLEX_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_NLRP3_INFLAMMASOME_COMPLEX_ASSEMBLY | 8 | 3 | 15632 | 1249 |
Mefv,Tlr6,Eif2ak2 |
| 2.100e-02 | -3.86 | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN | MSigDB lists | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN | 8 | 3 | 15632 | 1249 |
Nr4a1,Trib3,Egln3 |
| 2.100e-02 | -3.86 | KOINUMA_COLON_CANCER_MSI_DN | MSigDB lists | KOINUMA_COLON_CANCER_MSI_DN | 8 | 3 | 15632 | 1249 |
Hsph1,Pmepa1,Chmp4b |
| 2.102e-02 | -3.86 | GO_MACROMOLECULE_CATABOLIC_PROCESS | MSigDB lists | GO_MACROMOLECULE_CATABOLIC_PROCESS | 834 | 83 | 15632 | 1249 |
Ppp2r2a,Zhx2,Keap1,Psmb6,Zc3h12a,Uchl1,Herc6,Rnf19b,Usp31,Usp42,Ube2l6,Uba7,Oas2,Usp35,Rnaset2a,Smg7,Bfar,Rnf34,Tnfaip3,Pml,Rnf139,Ube2e1,Magohb,Psme1,Isg15,Psmb10,Usp18,Rffl,Rnf24,Casp3,Psma6,Mdm2,Birc2,Klhl25,Traf2,Psmb9,Ldlr,Tmem67,Znrf1,Polr2g,Dnajb2,Rnaset2b,Rnf145,Psme2,Zfp36,Slc9a1,Isg20,Dcp1a,Usp12,Rnf19a,Sirt1,Rnf14,Lnpep,Ankib1,Psmb8,Atm,Casp8,Ubr4,Pnpt1,Gpc1,Fbxo4,Herc3,Sdc4,Dnase1l3,Tnks1bp1,Chmp4b,Usp25,Xrn1,Znrf3,Trim13,Sdc1,Pgm1,Dcp2,Pttg1,Bnip3,Ctsc,Sdc2,Vcan,Cnot4,Sqstm1,Agrn,Crbn,Psmd10 |
| 2.102e-02 | -3.86 | CAIRO_LIVER_DEVELOPMENT_UP | MSigDB lists | CAIRO_LIVER_DEVELOPMENT_UP | 154 | 20 | 15632 | 1249 |
Evl,Marcksl1,Rcn1,Gpc1,Pdgfc,Igf2bp2,Snn,Gja1,Ednrb,Srm,Flrt3,Plk2,Plod2,Jun,Akt3,Tmeff1,Pdpn,Ifrd1,Dusp4,Syne2 |
| 2.107e-02 | -3.86 | GO_REGULATION_OF_FATTY_ACID_TRANSPORT | MSigDB lists | GO_REGULATION_OF_FATTY_ACID_TRANSPORT | 28 | 6 | 15632 | 1249 |
Edn1,Thbs1,Il1b,Syk,P2ry2,Irs2 |
| 2.107e-02 | -3.86 | GO_REGULATION_OF_PLATELET_ACTIVATION | MSigDB lists | GO_REGULATION_OF_PLATELET_ACTIVATION | 28 | 6 | 15632 | 1249 |
Ubash3b,Lyn,Adrb2,Plek,Syk,Pdgfb |
| 2.107e-02 | -3.86 | GO_NEGATIVE_REGULATION_OF_CELL_MATRIX_ADHESION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_MATRIX_ADHESION | 28 | 6 | 15632 | 1249 |
Acvrl1,Mmp14,Thbs1,Bcl6,Serpine1,Src |
| 2.107e-02 | -3.86 | GO_MUSCLE_ADAPTATION | MSigDB lists | GO_MUSCLE_ADAPTATION | 28 | 6 | 15632 | 1249 |
Cflar,Il15,Hmox1,Psmb9,Kdm4a,Il1b |
| 2.107e-02 | -3.86 | GO_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER | MSigDB lists | GO_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER | 28 | 6 | 15632 | 1249 |
Icam1,F11r,Rapgef2,Myadm,Rap2c,Ezr |
| 2.107e-02 | -3.86 | GO_REGULATION_OF_INTERLEUKIN_4_PRODUCTION | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_4_PRODUCTION | 28 | 6 | 15632 | 1249 |
Nlrp3,Cd86,H2-Eb1,Tnfsf4,Cd83,Irf4 |
| 2.107e-02 | -3.86 | GO_CELLULAR_RESPONSE_TO_VITAMIN | MSigDB lists | GO_CELLULAR_RESPONSE_TO_VITAMIN | 28 | 6 | 15632 | 1249 |
Fzd1,Mdm2,Tnc,Il15,Pim1,Ccl5 |
| 2.107e-02 | -3.86 | GO_HISTONE_ACETYLTRANSFERASE_BINDING | MSigDB lists | GO_HISTONE_ACETYLTRANSFERASE_BINDING | 28 | 6 | 15632 | 1249 |
Pla2g4a,Egr1,Kat2b,Hif1a,Cited2,Nr4a3 |
| 2.107e-02 | -3.86 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | MSigDB lists | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | 28 | 6 | 15632 | 1249 |
Tap2,H2-Q6,Sec24b,Tap1,H2-Q4,H2-Q7 |
| 2.107e-02 | -3.86 | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | MSigDB lists | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | 28 | 6 | 15632 | 1249 |
Timp1,Sat1,Nr4a1,Prdx1,Cd82,Serpinb2 |
| 2.107e-02 | -3.86 | GO_REGULATION_OF_T_CELL_MIGRATION | MSigDB lists | GO_REGULATION_OF_T_CELL_MIGRATION | 28 | 6 | 15632 | 1249 |
Ccl5,Itga4,Cxcl10,Tnfsf14,Tnfrsf14,Ripk3 |
| 2.107e-02 | -3.86 | BIOCARTA_NKT_PATHWAY | MSigDB lists | BIOCARTA_NKT_PATHWAY | 28 | 6 | 15632 | 1249 |
Ccl4,Ccr3,Ccr1,Il12b,Il4ra,Il12rb1 |
| 2.107e-02 | -3.86 | CAFFAREL_RESPONSE_TO_THC_DN | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_DN | 28 | 6 | 15632 | 1249 |
Dnaja1,Hspa2,Mcm6,Serpinb2,Pnp2,Hsph1 |
| 2.111e-02 | -3.86 | response to insulin | biological process | GO:0032868 | 169 | 19 | 20694 | 1406 |
Ptpn2,Sirt1,Slc9a1,Trib3,Akt3,Stat1,Phip,Egr2,Stxbp3,Rhoq,Socs7,Cyfip1,Igf1r,Pde3b,Rab10,Egr1,Irs2,Kat2b,Sesn3 |
| 2.114e-02 | -3.86 | thiol-dependent ubiquitin-specific protease activity | molecular function | GO:0004843 | 90 | 12 | 20217 | 1400 |
Usp31,Tank,Otud1,Usp25,Vcpip1,Usp18,Uchl1,Usp42,Usp12,Zc3h12a,Tnfaip3,Usp35 |
| 2.115e-02 | -3.86 | EPPERT_HSC_R | MSigDB lists | EPPERT_HSC_R | 106 | 15 | 15632 | 1249 |
St3gal6,Ptk2,Dram1,Crim1,Gcnt2,Jun,Hopx,Dusp6,Dach1,Rbpms,Mafk,Pnp2,Abcb1a,Ksr1,Zeb1 |
| 2.115e-02 | -3.86 | GO_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | MSigDB lists | GO_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | 106 | 15 | 15632 | 1249 |
Zc3h12a,Ptk2,Sema4a,Ptgs2,Kdr,Thbs1,Angpt1,Vegfc,Notch1,Stat5a,Nrp2,Pdgfb,Edn1,Acvrl1,Met |
| 2.120e-02 | -3.85 | F_BAR | interpro domains | IPR031160 | 23 | 5 | 19984 | 1430 |
Pstpip2,Fnbp1l,Trip10,Fcho2,Fchsd2 |
| 2.120e-02 | -3.85 | TNFR/NGFR_Cys_rich_reg | interpro domains | IPR001368 | 23 | 5 | 19984 | 1430 |
Tnfrsf14,Tnfrsf8,Tnfrsf1b,Cd40,Fas |
| 2.120e-02 | -3.85 | IL-7 Signaling Pathway | WikiPathways | WP297 | 44 | 10 | 4813 | 540 |
Lyn,Stat3,Irs2,Stat1,Ccnd2,Stat5a,Map2k1,Il2rg,Irf1,Bcl2l11 |
| 2.121e-02 | -3.85 | GSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 164 | 21 | 15632 | 1249 |
Tnfsf8,Ppp4r2,Setdb2,Procr,Rap1gap2,Tra2a,Sod2,Txn1,Serpine1,Rhof,Rnaset2a,Rbm43,Tax1bp1,Vrk2,Rnaset2b,Clec4a1,Slc37a3,Xrn1,Slco3a1,Sertad3,Usp42 |
| 2.121e-02 | -3.85 | GO_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 164 | 21 | 15632 | 1249 |
Lpar1,Icam1,Cdc42ep4,Spire1,Nck1,Evl,Hck,Sdc4,Whamm,Hcls1,Cdc42ep2,Cyfip1,Cav1,Swap70,Plek,Csf3,Rictor,Vasp,Edn1,Prkce,Stap1 |
| 2.121e-02 | -3.85 | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN | MSigDB lists | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN | 164 | 21 | 15632 | 1249 |
Ccr1,Rabgef1,Txn1,Itpr1,Tnfsf14,Gem,Atp6v1d,Serpine1,Csf1,Edn1,Spry2,Tnfsf15,Mafk,Rnf19a,Acvr1,Atf3,Trib1,Upp1,St3gal6,Snapc1,Rgs1 |
| 2.121e-02 | -3.85 | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP | 164 | 21 | 15632 | 1249 |
Ttc39b,Cox18,Upp1,Cmpk2,Esd,Fam162a,Ripk3,Aff1,Fbxo4,Pde3b,Actb,Bcl2a1a,Rhof,Arhgef3,Itgav,Bcl2a1b,Snx10,Dusp1,Bcl2a1d,Mdm2,Ppp2r5a |
| 2.121e-02 | -3.85 | GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN | 164 | 21 | 15632 | 1249 |
Rab3ip,Pkp4,Aff1,Chd9,Fbxo4,Pde3b,Azi2,Mpp7,Fam111a,Tapbpl,Kat2b,Egr1,Egr3,Il18rap,Dock10,Psme2,Timeless,Wdr59,Cenpj,Golga3,Itpr1 |
| 2.121e-02 | -3.85 | GSE3982_EOSINOPHIL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_BASOPHIL_DN | 164 | 21 | 15632 | 1249 |
Pikfyve,Dtwd1,Map2k4,Ddx58,Rnf139,Palld,Sema4c,Pdgfc,Pbx1,Prdx1,Tpst1,Rrs1,Sema3c,Map4k4,Abcc5,Dpy19l1,Mmd,Optn,Ppp2r5a,Ext1,Fut8 |
| 2.121e-02 | -3.85 | ESC_J1_UP_EARLY.V1_DN | MSigDB lists | ESC_J1_UP_EARLY.V1_DN | 164 | 21 | 15632 | 1249 |
Junb,Tagln,Dusp6,Serpine1,Adap2,Edn1,Stat3,Mdn1,Zfp36,Myc,Ppp2r3a,Cebpd,Uba7,Tlr9,Egr1,Socs3,Trib3,Slc30a1,Zbp1,Gbp2,Relb |
| 2.121e-02 | -3.85 | GO_RECEPTOR_SIGNALING_PROTEIN_ACTIVITY | MSigDB lists | GO_RECEPTOR_SIGNALING_PROTEIN_ACTIVITY | 164 | 21 | 15632 | 1249 |
Fcgr1,Kdr,Ikbke,Daxx,Ripk3,Acvr1b,Nsmaf,Map3k8,Lyn,Il4ra,Map2k4,Acvr1,Acvrl1,Map3k6,Syk,Flrt3,Map4k4,Rgs14,Itpr1,Flrt2,Map2k1 |
| 2.121e-02 | -3.85 | GO_ACIDIC_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_ACIDIC_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 14 | 4 | 15632 | 1249 |
Slc25a12,Slc25a22,Slc13a3,Slc7a11 |
| 2.121e-02 | -3.85 | GO_POSITIVE_REGULATION_OF_CHOLESTEROL_EFFLUX | MSigDB lists | GO_POSITIVE_REGULATION_OF_CHOLESTEROL_EFFLUX | 14 | 4 | 15632 | 1249 |
Nfkbia,Nr1h3,Ptch1,Sirt1 |
| 2.121e-02 | -3.85 | BIOCARTA_CCR5_PATHWAY | MSigDB lists | BIOCARTA_CCR5_PATHWAY | 14 | 4 | 15632 | 1249 |
Jun,Fos,Ccl12,Ccl4 |
| 2.121e-02 | -3.85 | GO_RESPIRATORY_BURST | MSigDB lists | GO_RESPIRATORY_BURST | 14 | 4 | 15632 | 1249 |
Nox1,Cd55,Hck,Pik3cd |
| 2.121e-02 | -3.85 | MODULE_191 | MSigDB lists | MODULE_191 | 14 | 4 | 15632 | 1249 |
Ccl2,Myc,Cp,Ccl12 |
| 2.121e-02 | -3.85 | GO_HISTONE_H3_K9_MODIFICATION | MSigDB lists | GO_HISTONE_H3_K9_MODIFICATION | 14 | 4 | 15632 | 1249 |
Kat2b,Sirt1,Arid4a,Setdb2 |
| 2.121e-02 | -3.85 | ABBUD_LIF_SIGNALING_2_UP | MSigDB lists | ABBUD_LIF_SIGNALING_2_UP | 14 | 4 | 15632 | 1249 |
Dio2,Angpt1,Ezr,Junb |
| 2.121e-02 | -3.85 | XU_RESPONSE_TO_TRETINOIN_UP | MSigDB lists | XU_RESPONSE_TO_TRETINOIN_UP | 14 | 4 | 15632 | 1249 |
Alas1,Psmb9,Pim1,Rel |
| 2.121e-02 | -3.85 | GO_PYRIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_PYRIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS | 14 | 4 | 15632 | 1249 |
Nampt,Pnp2,Kmo,Me1 |
| 2.121e-02 | -3.85 | GO_REGULATION_OF_MITOCHONDRIAL_FISSION | MSigDB lists | GO_REGULATION_OF_MITOCHONDRIAL_FISSION | 14 | 4 | 15632 | 1249 |
Mul1,Kdr,Ddhd1,Bnip3 |
| 2.121e-02 | -3.85 | GO_REGULATION_OF_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 14 | 4 | 15632 | 1249 |
Ptpn2,Src,Ptprj,Ptgir |
| 2.121e-02 | -3.85 | GO_REGULATION_OF_CAMP_DEPENDENT_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_CAMP_DEPENDENT_PROTEIN_KINASE_ACTIVITY | 14 | 4 | 15632 | 1249 |
Rapgef2,Atp2b4,Sirt1,Prkar2b |
| 2.121e-02 | -3.85 | GO_POSITIVE_REGULATION_OF_P38MAPK_CASCADE | MSigDB lists | GO_POSITIVE_REGULATION_OF_P38MAPK_CASCADE | 14 | 4 | 15632 | 1249 |
Gadd45g,Gadd45b,Bmp2,Zc3h12a |
| 2.121e-02 | -3.85 | GO_POSITIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION | 14 | 4 | 15632 | 1249 |
Csf1,Nfkb1,Msr1,Pf4 |
| 2.121e-02 | -3.85 | BIOCARTA_PLATELETAPP_PATHWAY | MSigDB lists | BIOCARTA_PLATELETAPP_PATHWAY | 14 | 4 | 15632 | 1249 |
Serpine1,Plat,Plau,Col4a2 |
| 2.121e-02 | -3.85 | GO_REGULATION_OF_CALCINEURIN_NFAT_SIGNALING_CASCADE | MSigDB lists | GO_REGULATION_OF_CALCINEURIN_NFAT_SIGNALING_CASCADE | 14 | 4 | 15632 | 1249 |
Atp2b4,Prnp,Rcan1,Slc9a1 |
| 2.121e-02 | -3.85 | GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | 14 | 4 | 15632 | 1249 |
Hlx,Tnfsf4,Il4ra,Bcl6 |
| 2.121e-02 | -3.85 | TIAN_BHLHA15_TARGETS | MSigDB lists | TIAN_BHLHA15_TARGETS | 14 | 4 | 15632 | 1249 |
Acp2,Slc31a2,Fndc3a,Tifa |
| 2.121e-02 | -3.85 | GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_SIGNALING_PATHWAY | MSigDB lists | GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_SIGNALING_PATHWAY | 14 | 4 | 15632 | 1249 |
Pdgfrb,Nrp2,Flt1,Kdr |
| 2.121e-02 | -3.85 | GO_CELLULAR_RESPONSE_TO_STEROL | MSigDB lists | GO_CELLULAR_RESPONSE_TO_STEROL | 14 | 4 | 15632 | 1249 |
Hmgcs1,Lrp8,Inhba,Ptch1 |
| 2.121e-02 | -3.85 | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE | 14 | 4 | 15632 | 1249 |
St3gal3,Fut8,St3gal1,B4galt4 |
| 2.121e-02 | -3.85 | GO_3_5_CYCLIC_AMP_PHOSPHODIESTERASE_ACTIVITY | MSigDB lists | GO_3_5_CYCLIC_AMP_PHOSPHODIESTERASE_ACTIVITY | 14 | 4 | 15632 | 1249 |
Pde7b,Pde4b,Pde1b,Pde3b |
| 2.123e-02 | -3.85 | MUELLER_PLURINET | MSigDB lists | MUELLER_PLURINET | 276 | 32 | 15632 | 1249 |
Stip1,Mcm6,Sirt1,Vasp,Nfkbib,Stxbp3,Trip13,Plscr1,Fubp1,Ccne1,Daxx,Tnfrsf8,Pbx1,Zfp281,Prnp,Rnd1,Socs1,Tpx2,Arl4a,Mcm10,Ccnd1,Rbpms,Hdac1,Hspa2,Psma6,Phgdh,Pnp2,Myc,Hmga1,Cenpe,Hsph1,Psip1 |
| 2.125e-02 | -3.85 | axo-dendritic transport | biological process | GO:0008088 | 71 | 10 | 20694 | 1406 |
Rab21,Hap1,Uchl1,Ap3b1,Stau1,Ap3m2,Dst,Hif1a,Dync1h1,Kif5c |
| 2.125e-02 | -3.85 | phosphatidylinositol 3-kinase binding | molecular function | GO:0043548 | 41 | 7 | 20217 | 1400 |
Irs2,Igf1r,Met,Ptk2,Pdgfrb,Axl,Jak2 |
| 2.128e-02 | -3.85 | signaling pattern recognition receptor activity | molecular function | GO:0008329 | 16 | 4 | 20217 | 1400 |
Ptafr,Tlr2,Tlr9,Trim12c |
| 2.130e-02 | -3.85 | GO_PROTEIN_COMPLEX_BIOGENESIS | MSigDB lists | GO_PROTEIN_COMPLEX_BIOGENESIS | 1039 | 101 | 15632 | 1249 |
H2-Eb1,Brd2,Gja1,Ccl5,Stxbp3,Snx2,Vasp,Hmox1,Cox18,Fcho2,Pilrb1,Sec24a,Ikbke,Keap1,Tnf,Traf2,Micall2,Hdac1,Nupr1,Cd74,Cutc,Pdgfc,Apaf1,Tnfaip3,Sco1,Cav1,Casp8,Cenpj,Trim21,Slc9a1,Kctd12,Dgkh,Ptk2,Max,Gfpt1,Jak2,Ppp2r1b,H3f3b,Sqstm1,Sod2,Nlrc4,Hmga1,Ctsc,Evl,Nck1,Fas,Nek6,Tpx2,Cx3cl1,Pilrb2,Me1,Tle3,Gch1,Zc3h12a,Oas1g,Kcna3,Sec24b,Ehd1,Src,Ppp6r1,Lrp4,Slc2a1,Birc2,Cd40,Mdn1,Dbnl,Mdm2,Mlkl,Tapbp,Acvrl1,Malt1,Apba1,Pml,Traf1,Trim12c,Nod1,Daxx,Ripk3,Birc3,Bcl9,Pdss1,Oas1a,Rasgrp1,Hat1,Kpna3,Adrb2,Asf1a,Hcls1,Pfkl,Igf1r,Cenpe,Psmd10,Kcnj2,Myc,Nod2,Prnp,Nlrp3,Pnpt1,Chmp4b,Samhd1,Angpt1 |
| 2.131e-02 | -3.85 | MEK_UP.V1_UP | MSigDB lists | MEK_UP.V1_UP | 174 | 22 | 15632 | 1249 |
Igf2bp2,Abcc4,Tgfbi,Acsl1,Ptger4,Ell2,Egln3,Vasp,Pdlim7,Slc2a6,Eno2,Gdf15,Etv5,Plau,Trp53i11,Il4ra,Lrp8,Chst11,Dusp4,Edn1,Rai14,Slc7a11 |
| 2.131e-02 | -3.85 | GSE46468_LUNG_INNATE_LYMPHOID_CELL_VS_SPLEEN_CD4_TCELL_DN | MSigDB lists | GSE46468_LUNG_INNATE_LYMPHOID_CELL_VS_SPLEEN_CD4_TCELL_DN | 174 | 22 | 15632 | 1249 |
Zeb1,Zfp36,Usp12,Rnf19a,Eef1e1,Gsr,Hsph1,Nr4a1,Sqstm1,Txnrd1,Ppp1r15b,Tnfsf14,Ppp1r15a,Med21,Cd83,Egr3,Psmb6,Csrnp1,Tab2,Ier3,Sphk1,Traf1 |
| 2.131e-02 | -3.85 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_DN | 174 | 22 | 15632 | 1249 |
Rgl1,Jarid2,Tuba4a,Plekhf2,Gch1,Ddhd1,Maff,Casp3,Ccdc86,Prnp,Plagl1,Ppm1l,Il18,Marcksl1,Atf3,Socs3,Tagap,Klf7,Wdr43,Pim3,Cd83,Bambi |
| 2.131e-02 | -3.85 | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | MSigDB lists | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | 174 | 22 | 15632 | 1249 |
Atp2b4,Atp11a,Icam1,Nr3c1,Cish,Peli1,Rbpms,Cebpd,Dusp1,Map3k6,Nfkbia,Dpy19l1,Tiparp,Cited2,Cd55,St3gal5,Rapgef2,Ppp2r3a,Hopx,Rel,Gem,Rims3 |
| 2.131e-02 | -3.85 | GSE3982_BCELL_VS_NKCELL_UP | MSigDB lists | GSE3982_BCELL_VS_NKCELL_UP | 174 | 22 | 15632 | 1249 |
Irf8,Tor3a,Pde4b,Hk2,Isg20,Ampd3,Ebi3,Larp1,Ppa1,Cd200,Clic4,Dse,Tspan3,Swap70,Bcl6,Ezr,Irgq,Fcgr2b,Irf4,Rhoh,Sav1,Ciita |
| 2.131e-02 | -3.85 | BOQUEST_STEM_CELL_UP | MSigDB lists | BOQUEST_STEM_CELL_UP | 245 | 29 | 15632 | 1249 |
Lox,Lpar1,C3,Ust,Notch2,Sema3c,Flrt2,Pid1,Ltbp2,Inhba,Slc39a14,Htra1,Irs2,Plagl1,Lif,Tmem176b,Angpt1,Olfml3,F10,Cd302,Dse,Timp1,Axl,C1ra,Cxcl14,Sdc2,Vcan,Tnc,Pla2g4a |
| 2.132e-02 | -3.85 | GSE27786_BCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_BCELL_VS_NKTCELL_UP | 184 | 23 | 15632 | 1249 |
Ube2e1,Treml2,Nfkbie,Setdb2,Carhsp1,Stard5,Slc15a3,Lrch1,Nr4a3,Rnf19b,Mtmr14,St3gal1,Mtdh,Rsbn1,Nampt,Pde4b,Leng9,Stoml1,Nfkbid,Bst1,Med13,Slc2a6,Icosl |
| 2.132e-02 | -3.85 | GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_UP | MSigDB lists | GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_UP | 184 | 23 | 15632 | 1249 |
Ccng2,Ly75,Aoah,P4ha2,Klf6,Bcl2l11,Herc3,Traf5,Pde3b,Tnfrsf8,Ccl22,Socs1,Slc39a14,Spint2,Timeless,Rrs1,Psd4,Abcc1,Nfil3,Il1rn,Serpinb2,Ptk2,Dck |
| 2.132e-02 | -3.85 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN | 184 | 23 | 15632 | 1249 |
Rgs1,Serpinb9,Ttc39b,Trib3,St3gal1,Uba7,Ube2e2,Pstpip2,Dmwd,Sipa1l1,Eno2,Irak3,Chmp4b,Gng11,Pbx1,Slc48a1,Col4a2,Traf1,Upp1,F11r,Palld,Scarf1,Ets2 |
| 2.132e-02 | -3.85 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_DN | 184 | 23 | 15632 | 1249 |
Nfkbie,Chst11,Rab11fip1,Phgdh,D16Ertd472e,Oas3,Tnf,Tap1,Sla,Sdc4,Tpx2,Pdss1,Plscr1,Timeless,Slc7a5,Trim21,Trim26,Il10,Tor3a,Hsd17b12,Ccr1,Pdk3,Cd200 |
| 2.132e-02 | -3.85 | GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_UP | MSigDB lists | GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_UP | 184 | 23 | 15632 | 1249 |
Nfkbie,Ampd3,Pdgfb,Csf1,Csf3r,Zc3h12c,Arhgef3,Ass1,Ap3m2,Ppfibp1,Igf1r,Plaur,Rgs3,Dusp16,Traf5,Batf,Dek,Gbp3,Arrdc4,Fam111a,Traf3ip2,Nfkbil1,Rnf19b |
| 2.133e-02 | -3.85 | negative regulation of cell-substrate adhesion | biological process | GO:0010812 | 61 | 9 | 20694 | 1406 |
Bcl6,Thbs1,Acvrl1,Src,Gcnt2,Serpine1,Mmp14,Notch1,Jag1 |
| 2.133e-02 | -3.85 | nucleotide phosphorylation | biological process | GO:0046939 | 61 | 9 | 20694 | 1406 |
Pgk1,Eno2,Tpi1,Cmpk2,Hk1,Hk2,Pfkl,Ak4,Hk3 |
| 2.141e-02 | -3.84 | mouse chr2|2 C2 | chromosome location | mouse chr2|2 C2 | 27 | 5 | 24173 | 1464 |
Cers6,Hat1,Dhrs9,Slc25a12,Ccdc173 |
| 2.145e-02 | -3.84 | Death | pfam domains | PF00531 | 31 | 6 | 18711 | 1348 |
Nfkb2,Irak2,Nfkb1,Irak3,Fas,Myd88 |
| 2.171e-02 | -3.83 | phosphate acquisition | BIOCYC pathways | MOUSE_PWY-6348 | 7 | 3 | 1025 | 97 |
Acp2,Acpp,Acp5 |
| 2.172e-02 | -3.83 | GO_NEGATIVE_REGULATION_OF_STAT_CASCADE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_STAT_CASCADE | 44 | 8 | 15632 | 1249 |
Cish,Socs7,Socs3,Flrt3,Socs1,Ptpn2,Cav1,Flrt2 |
| 2.172e-02 | -3.83 | GO_LYMPHOCYTE_MIGRATION | MSigDB lists | GO_LYMPHOCYTE_MIGRATION | 44 | 8 | 15632 | 1249 |
Ccl5,Ccl12,Ccl22,Cx3cl1,Pik3cd,Cxcl10,Ccl2,Ccl3 |
| 2.172e-02 | -3.83 | HENDRICKS_SMARCA4_TARGETS_UP | MSigDB lists | HENDRICKS_SMARCA4_TARGETS_UP | 44 | 8 | 15632 | 1249 |
Jun,Ccl12,Phldb1,Itga5,Cdkn1a,Dcbld2,Atp2b4,Flnb |
| 2.172e-02 | -3.83 | BURTON_ADIPOGENESIS_4 | MSigDB lists | BURTON_ADIPOGENESIS_4 | 44 | 8 | 15632 | 1249 |
Tsku,Rhou,Rcl1,Ppp2r1b,Col4a2,Bcl6,Ldha,Col18a1 |
| 2.172e-02 | -3.83 | BCAT.100_UP.V1_UP | MSigDB lists | BCAT.100_UP.V1_UP | 44 | 8 | 15632 | 1249 |
Abcb1a,Gadd45g,Dusp4,Etv5,Dusp6,Slc7a8,Eno2,Itga9 |
| 2.172e-02 | -3.83 | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | MSigDB lists | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | 44 | 8 | 15632 | 1249 |
Psma6,Psme2,Psmb9,Psmd10,Psmb10,Psme1,Psmb8,Psmb6 |
| 2.173e-02 | -3.83 | GSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_DN | MSigDB lists | GSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_DN | 135 | 18 | 15632 | 1249 |
Crim1,Samhd1,Filip1l,Socs3,Pttg1,Ccnd2,Ifit3b,Slco3a1,Peli1,Il18rap,Xaf1,Clic5,Slc31a2,Cx3cr1,Ifit3,Cyfip1,Higd1a,Rhbdf2 |
| 2.174e-02 | -3.83 | LAIHO_COLORECTAL_CANCER_SERRATED_UP | MSigDB lists | LAIHO_COLORECTAL_CANCER_SERRATED_UP | 97 | 14 | 15632 | 1249 |
Rin2,Optn,Peli1,Pla2g4a,Tcf4,Lcp2,Cav1,Pdgfc,Sec24a,Sgcb,Hif1a,Prnp,Palld,Ddx60 |
| 2.179e-02 | -3.83 | Parkinsons Disease Pathway | WikiPathways | WP3638 | 38 | 9 | 4813 | 540 |
Apaf1,Cycs,Uba7,Casp3,Casp2,Ube2l6,Uchl1,Ccne1,Casp7 |
| 2.182e-02 | -3.83 | The AIM2 inflammasome | REACTOME pathways | R-MMU-844615 | 3 | 2 | 8608 | 757 |
Aim2,Casp1 |
| 2.182e-02 | -3.83 | c-src mediated regulation of Cx43 function and closure of gap junctions | REACTOME pathways | R-MMU-191647 | 3 | 2 | 8608 | 757 |
Src,Gja1 |
| 2.182e-02 | -3.83 | MET activates STAT3 | REACTOME pathways | R-MMU-8875791 | 3 | 2 | 8608 | 757 |
Met,Stat3 |
| 2.182e-02 | -3.83 | Interconversion of polyamines | REACTOME pathways | R-MMU-351200 | 3 | 2 | 8608 | 757 |
Sat1,Smox |
| 2.182e-02 | -3.83 | Formation of apoptosome | REACTOME pathways | R-MMU-111458 | 3 | 2 | 8608 | 757 |
Cycs,Apaf1 |
| 2.182e-02 | -3.83 | Regulation of gap junction activity | REACTOME pathways | R-MMU-191650 | 3 | 2 | 8608 | 757 |
Src,Gja1 |
| 2.185e-02 | -3.82 | cyclin-dependent protein kinase holoenzyme complex | cellular component | GO:0000307 | 42 | 7 | 20747 | 1409 |
Ccne1,Ccnd1,Cdkn2d,Ccng2,Ccnj,Cdkn1a,Ccnd2 |
| 2.187e-02 | -3.82 | MARSON_FOXP3_TARGETS_UP | MSigDB lists | MARSON_FOXP3_TARGETS_UP | 61 | 10 | 15632 | 1249 |
Lrrc8c,Dusp4,Samhd1,Ddit4,Pnp2,Irf8,Swap70,Rcsd1,Psmb8,Itgav |
| 2.187e-02 | -3.82 | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_DN | MSigDB lists | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_DN | 61 | 10 | 15632 | 1249 |
Cebpd,Hck,Vcan,Cst7,Palld,S100a8,Plek,Tnf,Irf8,Ms4a6d |
| 2.187e-02 | -3.82 | KEGG_GLIOMA | MSigDB lists | KEGG_GLIOMA | 61 | 10 | 15632 | 1249 |
Pik3cd,Pdgfrb,Map2k1,Pik3r5,Mdm2,Igf1r,Ccnd1,Cdkn1a,Akt3,Pdgfb |
| 2.187e-02 | -3.82 | HOWLIN_PUBERTAL_MAMMARY_GLAND | MSigDB lists | HOWLIN_PUBERTAL_MAMMARY_GLAND | 61 | 10 | 15632 | 1249 |
Marco,Msr1,Slc30a1,Tnf,Col18a1,Egr1,Gsta3,Nfil3,Fcgr2b,Idi1 |
| 2.187e-02 | -3.82 | PID_ERA_GENOMIC_PATHWAY | MSigDB lists | PID_ERA_GENOMIC_PATHWAY | 61 | 10 | 15632 | 1249 |
Lmo4,Jun,Stat5a,Col18a1,C3,Hdac1,Ncoa7,Ccnd1,Myc,Cd82 |
| 2.187e-02 | -3.82 | GO_POSITIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | 61 | 10 | 15632 | 1249 |
Tnf,Ptgs2,Nr1h3,Fabp3,Nsmaf,Pla2g4a,Ldlr,Htr2a,Il1b,Htr2b |
| 2.187e-02 | -3.82 | White fat cell differentiation | WikiPathways | WP2872 | 32 | 8 | 4813 | 540 |
Irf4,Nr1h3,Klf2,Tle3,Cebpd,Nr3c1,Egr2,Stat5a |
| 2.190e-02 | -3.82 | glycolytic process | biological process | GO:0006096 | 42 | 7 | 20694 | 1406 |
Hk3,Hk1,Pgk1,Eno2,Tpi1,Hk2,Pfkl |
| 2.190e-02 | -3.82 | ATP generation from ADP | biological process | GO:0006757 | 42 | 7 | 20694 | 1406 |
Pfkl,Hk2,Tpi1,Eno2,Pgk1,Hk1,Hk3 |
| 2.190e-02 | -3.82 | positive regulation of sodium ion transport | biological process | GO:0010765 | 42 | 7 | 20694 | 1406 |
Scn1b,Slc9a1,Adrb2,Akt3,Mllt6,Cxcl1,Glrx |
| 2.190e-02 | -3.82 | regulation of spindle organization | biological process | GO:0090224 | 42 | 7 | 20694 | 1406 |
Gpsm2,Parp3,Tpx2,Hspa1b,Dync1h1,Chmp4b,Hspa1a |
| 2.196e-02 | -3.82 | MODULE_288 | MSigDB lists | MODULE_288 | 36 | 7 | 15632 | 1249 |
Fpr1,Fpr2,Ednrb,Ccr1,Cx3cr1,Ccl2,Ccr3 |
| 2.196e-02 | -3.82 | ZHAN_MULTIPLE_MYELOMA_CD1_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_DN | 36 | 7 | 15632 | 1249 |
Cpeb4,4930523C07Rik,F11r,Stard5,Adam19,Fut8,Rab3ip |
| 2.196e-02 | -3.82 | REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING | MSigDB lists | REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING | 36 | 7 | 15632 | 1249 |
St3gal3,Kat2b,Mov10,Jun,St3gal6,Notch2,Ccnd1 |
| 2.196e-02 | -3.82 | BIOCARTA_INTEGRIN_PATHWAY | MSigDB lists | BIOCARTA_INTEGRIN_PATHWAY | 36 | 7 | 15632 | 1249 |
Crkl,Src,Ptk2,Cav1,Zyx,Jun,Map2k1 |
| 2.196e-02 | -3.82 | BILANGES_RAPAMYCIN_SENSITIVE_GENES | MSigDB lists | BILANGES_RAPAMYCIN_SENSITIVE_GENES | 36 | 7 | 15632 | 1249 |
Gpd2,Acsl1,Ppm1l,Hap1,Tnfaip2,Slc12a9,Sat1 |
| 2.199e-02 | -3.82 | phospholipid biosynthetic process | biological process | GO:0008654 | 147 | 17 | 20694 | 1406 |
Sgms2,Pgap2,Hmgcs1,Agpat4,Plaat3,Atm,Dgka,Idi1,Lpcat2,Acsl5,Mppe1,Plscr1,Cept1,Pigv,Pgs1,Etnk1,Pik3cd |
| 2.204e-02 | -3.82 | organonitrogen compound catabolic process | biological process | GO:1901565 | 875 | 75 | 20694 | 1406 |
Dtx3l,Bnip3,Pde5a,Psmb6,Lnpep,Psmb10,Tha1,Cop1,Rnf19b,Gda,Kmo,Enpp4,Cnot4,Birc2,Tmem67,Uchl1,Dnajb2,Bfar,Psmb9,Rnf19a,Arrdc4,Klhl25,Psmb8,Dio2,Casp8,Pml,Uba7,Armc8,Asah2,Hdc,Smox,Znrf3,Rnf34,Apobec3,Mmp13,Usp42,Rffl,Mdm2,Arel1,Spsb1,Sirt1,Rnf139,Trim13,Tet2,Chmp4b,Isg15,Znrf1,Usp18,Crbn,Cemip2,Il4i1,Tnfaip3,Adhfe1,Hmox1,Keap1,Sat1,Smpdl3b,Ube2l6,Peli1,Fbxo4,Ubr4,Ldlr,Ctsc,Samhd1,Upp1,Usp25,Atm,Usp12,Traf2,Arg2,Nos2,Gpc1,Psma6,Rnf14,Ankib1 |
| 2.213e-02 | -3.81 | regulation of autophagy of mitochondrion | biological process | GO:1903146 | 33 | 6 | 20694 | 1406 |
Bnip3,Mul1,Tspo,Optn,Hk2,Hif1a |
| 2.213e-02 | -3.81 | positive regulation of response to endoplasmic reticulum stress | biological process | GO:1905898 | 33 | 6 | 20694 | 1406 |
Nck1,Ptpn2,Ppp1r15a,Tmem67,Sirt1,Fcgr2b |
| 2.213e-02 | -3.81 | prostaglandin metabolic process | biological process | GO:0006693 | 33 | 6 | 20694 | 1406 |
Ptgs2,Pdpn,Ptges,Cd74,Edn1,Sphk1 |
| 2.213e-02 | -3.81 | prostanoid metabolic process | biological process | GO:0006692 | 33 | 6 | 20694 | 1406 |
Sphk1,Edn1,Cd74,Ptges,Ptgs2,Pdpn |
| 2.213e-02 | -3.81 | negative regulation of muscle hypertrophy | biological process | GO:0014741 | 33 | 6 | 20694 | 1406 |
Tomm70a,Jarid2,Atp2b4,Tnfrsf1b,Errfi1,Notch1 |
| 2.213e-02 | -3.81 | positive regulation of neutrophil migration | biological process | GO:1902624 | 33 | 6 | 20694 | 1406 |
Edn1,Il1b,Il1a,Sell,Ptger4,Cd74 |
| 2.214e-02 | -3.81 | DELYS_THYROID_CANCER_DN | MSigDB lists | DELYS_THYROID_CANCER_DN | 215 | 26 | 15632 | 1249 |
Dnase1l3,Lipg,Cdc42ep2,Bmp2,Gng11,Aldh1b1,Arl4a,P2ry14,Egr1,Ier2,Hhex,Fgl2,Sdc2,Egr2,Jun,Cited2,Itpr1,Fos,Dio2,Tnfsf10,Prkx,Dnajb4,Phyh,Pla2g7,Fosb,Flrt2 |
| 2.215e-02 | -3.81 | Bcl2_BH2_motif_CS | interpro domains | IPR020726 | 9 | 3 | 19984 | 1430 |
Bcl2a1d,Bcl2a1a,Bcl2a1b |
| 2.215e-02 | -3.81 | PDGF/VEGF_dom | interpro domains | IPR000072 | 9 | 3 | 19984 | 1430 |
Vegfc,Pdgfc,Pdgfb |
| 2.215e-02 | -3.81 | DnaJ_C | interpro domains | IPR002939 | 9 | 3 | 19984 | 1430 |
Dnaja2,Dnajb4,Dnaja1 |
| 2.215e-02 | -3.81 | GTPase-bd | interpro domains | IPR010473 | 9 | 3 | 19984 | 1430 |
Fmnl2,Daam1,Diaph2 |
| 2.215e-02 | -3.81 | JmjN | interpro domains | IPR003349 | 9 | 3 | 19984 | 1430 |
Kdm5b,Jarid2,Kdm4a |
| 2.215e-02 | -3.81 | Bcl2_BH1_motif_CS | interpro domains | IPR020717 | 9 | 3 | 19984 | 1430 |
Bcl2a1a,Bcl2a1d,Bcl2a1b |
| 2.215e-02 | -3.81 | HSP40/DnaJ_pept-bd | interpro domains | IPR008971 | 9 | 3 | 19984 | 1430 |
Dnaja2,Dnajb4,Dnaja1 |
| 2.215e-02 | -3.81 | FH3_dom | interpro domains | IPR010472 | 9 | 3 | 19984 | 1430 |
Daam1,Fmnl2,Diaph2 |
| 2.217e-02 | -3.81 | Removal of licensing factors from origins | REACTOME pathways | R-MMU-69300 | 72 | 12 | 8608 | 757 |
Psma6,Psmb6,Psme2,Psme2b,Psmd10,Psme1,Psmb8,Psmb9,Mcm6,Mcm10,Cdkn1a,Psmb10 |
| 2.217e-02 | -3.81 | GO_UBIQUITIN_LIKE_PROTEIN_SPECIFIC_PROTEASE_ACTIVITY | MSigDB lists | GO_UBIQUITIN_LIKE_PROTEIN_SPECIFIC_PROTEASE_ACTIVITY | 88 | 13 | 15632 | 1249 |
Otud1,Usp53,Usp12,Usp35,Usp18,Usp42,Usp31,Usp25,Uchl1,Zc3h12a,Vcpip1,Tnfaip3,Tnip1 |
| 2.217e-02 | -3.81 | GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT | MSigDB lists | GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT | 88 | 13 | 15632 | 1249 |
Cnot4,Ccnd1,Mdm2,Casp2,Btg2,Plk2,Cenpj,Atm,Cdkn1a,Tnks1bp1,Plagl1,Plk3,Pml |
| 2.217e-02 | -3.81 | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | 88 | 13 | 15632 | 1249 |
Plagl1,Plk3,Pml,Cdkn1a,Tnks1bp1,Plk2,Cenpj,Atm,Cnot4,Ccnd1,Mdm2,Casp2,Btg2 |
| 2.217e-02 | -3.81 | GO_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | MSigDB lists | GO_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | 88 | 13 | 15632 | 1249 |
Prdx1,Arg2,Nox1,Prdx5,Nqo1,Edn1,Pdgfb,Ddit4,Bnip3,Slc7a2,Nos2,Gch1,Sod2 |
| 2.220e-02 | -3.81 | receptor metabolic process | biological process | GO:0043112 | 103 | 13 | 20694 | 1406 |
Calcrl,Cav1,Tnf,Syk,Fut8,Znrf3,Htr2b,Ezr,Il10,Scyl2,Caml,Agrn,Grk3 |
| 2.222e-02 | -3.81 | protein-containing complex assembly | biological process | GO:0065003 | 1356 | 111 | 20694 | 1406 |
Ikbke,Tifa,Lrp4,Kcna3,Traf2,Marcks,Tapbpl,Hcls1,Tapbp,Map2k1,Rrs1,Micall2,Lcn2,Kcnj2,Cox17,Adar,Ripk3,Hmox1,Cycs,Sbds,Mx2,Nlrc4,Mx1,Hat1,Chmp4b,Pdss1,Nlrp3,Mcm6,Zc3h12a,Apba1,Mdn1,Optn,Hopx,Pnpt1,Ehd1,Cenpe,Cenpj,Mcoln2,Sco1,Birc3,Asf1a,Apaf1,Pf4,Evl,Nupr1,Fas,Tap2,Nod2,Trim21,Birc2,Homer1,Dgkh,Ptk2,Plagl2,Cox18,Vasp,G3bp2,Samhd1,Prnp,Coa5,Keap1,Psmd10,Cav1,Itpr1,Dnaaf3,Gja1,Sqstm1,Dbnl,Diaph2,Kctd12,Txnrd1,Pdgfc,Slc2a1,Mmp9,Mdm2,Mlkl,Lrrc8c,Cx3cl1,Snx2,Daxx,Fcho2,Sod2,Tcf4,Stxbp1,Gfpt1,Rasgrp1,Gch1,Ago3,Acpp,Pml,Denr,Angpt1,Noct,Ikzf1,H3f3b,Pstpip2,Me1,Ccl5,Jmjd6,Cutc,Stxbp3,Brd2,Dync1h1,Igf1r,Pfkl,Psip1,Agrn,Cd74,Gsdmd,Malt1,Max |
| 2.224e-02 | -3.81 | C-C chemokine receptor activity | molecular function | GO:0016493 | 24 | 5 | 20217 | 1400 |
Xcr1,Ccrl2,Ccr1,Ccr3,Cx3cr1 |
| 2.226e-02 | -3.81 | GPVI-mediated activation cascade | REACTOME pathways | R-MMU-114604 | 48 | 9 | 8608 | 757 |
Pik3r5,Pik3r6,Il2rg,Pik3cd,Lyn,Lcp2,Jak2,Pdpn,Syk |
| 2.228e-02 | -3.80 | Nicotinamide salvaging | REACTOME pathways | R-MMU-197264 | 13 | 4 | 8608 | 757 |
Parp10,Parp9,Ptgs2,Nampt |
| 2.228e-02 | -3.80 | cGMP effects | REACTOME pathways | R-MMU-418457 | 13 | 4 | 8608 | 757 |
Pde5a,Pde3b,Itpr1,Pde1b |
| 2.229e-02 | -3.80 | female sex differentiation | biological process | GO:0046660 | 136 | 16 | 20694 | 1406 |
Axl,Dach1,Pla2g4a,Arid5b,Tiparp,Angpt1,Sirt1,Src,Stat5a,Inhba,Kitl,Serpine1,Nos2,Ahr,Atm,Kdr |
| 2.233e-02 | -3.80 | MODULE_562 | MSigDB lists | MODULE_562 | 21 | 5 | 15632 | 1249 |
Mmp13,Timp1,Mmp14,Mmp9,Tnf |
| 2.233e-02 | -3.80 | GO_MYELOID_DENDRITIC_CELL_ACTIVATION | MSigDB lists | GO_MYELOID_DENDRITIC_CELL_ACTIVATION | 21 | 5 | 15632 | 1249 |
Batf2,Irf4,Batf,Relb,Cd86 |
| 2.233e-02 | -3.80 | GO_REGULATION_OF_PROTEIN_PHOSPHATASE_TYPE_2A_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PROTEIN_PHOSPHATASE_TYPE_2A_ACTIVITY | 21 | 5 | 15632 | 1249 |
Ppp2r5a,Ppp2r1b,Eif2ak2,Ppp2r3a,Ppp2r2a |
| 2.233e-02 | -3.80 | GO_ENDOTHELIAL_CELL_PROLIFERATION | MSigDB lists | GO_ENDOTHELIAL_CELL_PROLIFERATION | 21 | 5 | 15632 | 1249 |
Prkx,Hmox1,Mmp14,Cd34,Acvrl1 |
| 2.233e-02 | -3.80 | GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | 21 | 5 | 15632 | 1249 |
Cited2,Acvrl1,Acvr1,Acvr1b,Inhba |
| 2.233e-02 | -3.80 | GO_REGULATION_OF_CAMP_MEDIATED_SIGNALING | MSigDB lists | GO_REGULATION_OF_CAMP_MEDIATED_SIGNALING | 21 | 5 | 15632 | 1249 |
Rapgef2,Cxcl10,Pf4,Pde3b,Ptgir |
| 2.233e-02 | -3.80 | GO_THREONINE_TYPE_PEPTIDASE_ACTIVITY | MSigDB lists | GO_THREONINE_TYPE_PEPTIDASE_ACTIVITY | 21 | 5 | 15632 | 1249 |
Psmb6,Psmb8,Psma6,Psmb10,Psmb9 |
| 2.233e-02 | -3.80 | GO_B_CELL_HOMEOSTASIS | MSigDB lists | GO_B_CELL_HOMEOSTASIS | 21 | 5 | 15632 | 1249 |
Bcl2l11,Casp3,Tnfaip3,Lyn,Hif1a |
| 2.233e-02 | -3.80 | MOOTHA_GLYCOLYSIS | MSigDB lists | MOOTHA_GLYCOLYSIS | 21 | 5 | 15632 | 1249 |
Eno2,Hk1,Tpi1,Eno1,Pgk1 |
| 2.233e-02 | -3.80 | SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_UP | MSigDB lists | SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_UP | 21 | 5 | 15632 | 1249 |
Tifa,Casp7,Lhx2,Msr1,Sgms2 |
| 2.233e-02 | -3.80 | YANG_BREAST_CANCER_ESR1_BULK_DN | MSigDB lists | YANG_BREAST_CANCER_ESR1_BULK_DN | 21 | 5 | 15632 | 1249 |
Plaur,Lad1,Dse,Tmem123,Nck1 |
| 2.233e-02 | -3.80 | GO_RESPONSE_TO_STEROL | MSigDB lists | GO_RESPONSE_TO_STEROL | 21 | 5 | 15632 | 1249 |
Lrp8,Ccl5,Hmgcs1,Ptch1,Inhba |
| 2.233e-02 | -3.80 | REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 | MSigDB lists | REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 | 21 | 5 | 15632 | 1249 |
Gng4,Gng11,Gnb4,Gng12,P2ry12 |
| 2.233e-02 | -3.80 | HOFMANN_MYELODYSPLASTIC_SYNDROM_RISK_UP | MSigDB lists | HOFMANN_MYELODYSPLASTIC_SYNDROM_RISK_UP | 21 | 5 | 15632 | 1249 |
Gdf15,Ier3,Dusp14,Ccnd1,Stip1 |
| 2.233e-02 | -3.80 | GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_INTERCONVERSION | MSigDB lists | GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_INTERCONVERSION | 21 | 5 | 15632 | 1249 |
Txnrd1,Txn1,Glrx,Gsr,Ak4 |
| 2.233e-02 | -3.80 | GO_IMMUNOGLOBULIN_PRODUCTION_INVOLVED_IN_IMMUNOGLOBULIN_MEDIATED_IMMUNE_RESPONSE | MSigDB lists | GO_IMMUNOGLOBULIN_PRODUCTION_INVOLVED_IN_IMMUNOGLOBULIN_MEDIATED_IMMUNE_RESPONSE | 21 | 5 | 15632 | 1249 |
Pou2f2,Swap70,Batf,H2-Ab1,H2-Eb1 |
| 2.233e-02 | -3.80 | GO_LEUKOCYTE_APOPTOTIC_PROCESS | MSigDB lists | GO_LEUKOCYTE_APOPTOTIC_PROCESS | 21 | 5 | 15632 | 1249 |
Fas,Bcl2l11,Il6,Traf3ip2,Hcar2 |
| 2.233e-02 | -3.80 | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | MSigDB lists | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | 21 | 5 | 15632 | 1249 |
Prdx5,Birc2,Serpinb9,Tnfsf14,Birc3 |
| 2.233e-02 | -3.80 | GO_POSITIVE_REGULATION_OF_NEUROBLAST_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_NEUROBLAST_PROLIFERATION | 21 | 5 | 15632 | 1249 |
Cx3cl1,Vegfc,Hif1a,Notch1,Cx3cr1 |
| 2.233e-02 | -3.80 | GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION | MSigDB lists | GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION | 21 | 5 | 15632 | 1249 |
Hk2,Txn1,Tspo,Sod2,Hk1 |
| 2.233e-02 | -3.80 | GO_GLUCOSE_6_PHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_GLUCOSE_6_PHOSPHATE_METABOLIC_PROCESS | 21 | 5 | 15632 | 1249 |
Tpi1,Hk1,Pgm1,Hk3,Hk2 |
| 2.233e-02 | -3.80 | chr2q23 | MSigDB lists | chr2q23 | 21 | 5 | 15632 | 1249 |
Pkp4,Acvr1,Fmnl2,Rnd3,Kif5c |
| 2.233e-02 | -3.80 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | MSigDB lists | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | 21 | 5 | 15632 | 1249 |
Jun,Ccnd1,Mov10,Kat2b,Notch2 |
| 2.234e-02 | -3.80 | IK3_01 | MSigDB lists | IK3_01 | 205 | 25 | 15632 | 1249 |
Rhoq,Slc44a1,Mecp2,Psd,Cept1,Nfkbia,Parp8,Fos,Cd40,Tsku,Apba1,Usp25,Egr1,Zeb1,Nfkbid,Jag1,Etv6,Map4k4,Sh3bgrl2,Pkp4,Dio2,Ptges,Egr3,Rtn1,Frmd4a |
| 2.234e-02 | -3.80 | GO_CELLULAR_RESPONSE_TO_CARBOHYDRATE_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_CARBOHYDRATE_STIMULUS | 70 | 11 | 15632 | 1249 |
Plau,Il1b,Fas,Ptger4,Irs2,Calcrl,Hif1a,Icam1,Nfkb1,Pdk3,Ppp1r15a |
| 2.234e-02 | -3.80 | LINDVALL_IMMORTALIZED_BY_TERT_DN | MSigDB lists | LINDVALL_IMMORTALIZED_BY_TERT_DN | 70 | 11 | 15632 | 1249 |
Plod2,Slc43a3,Ltbp2,Egr1,Eno2,Ptges,Vcan,Antxr1,Il6,Pdpn,Sat1 |
| 2.238e-02 | -3.80 | GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP | MSigDB lists | GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP | 155 | 20 | 15632 | 1249 |
Gbp3,Sell,Kcna3,Stat1,Ptk2,Pmepa1,Slc28a2,Rab3ip,Tnfrsf14,Crlf3,Pik3r6,Atp6v1d,Nlrc4,Map4k4,Oas2,Treml2,Sele,Tnfsf8,Myc,Peli1 |
| 2.238e-02 | -3.80 | LEE_LIVER_CANCER_SURVIVAL_DN | MSigDB lists | LEE_LIVER_CANCER_SURVIVAL_DN | 155 | 20 | 15632 | 1249 |
Mcm6,Mthfd2,Ier3,Hif1a,Odc1,Dyrk2,Igf1r,Cd164,Pbx1,Dek,Rnd3,Tspan3,Agrn,Rab32,B3gnt5,Eef1e1,Mmd,Pnp2,Peli1,Slc44a1 |
| 2.239e-02 | -3.80 | CEBP_Q2_01 | MSigDB lists | CEBP_Q2_01 | 246 | 29 | 15632 | 1249 |
Pla2g4a,Cept1,Dync1h1,Jun,Bcl6,Lipg,Gys1,Il27,Angpt1,Spred1,Crim1,Etv5,Nfkbiz,Slc39a13,Tnfsf15,Nrp2,Etv6,Ube2e2,Hivep3,Sik3,Lmo4,Asah2,Tnfsf14,Acsl5,Pcdh7,Nfil3,H3f3b,Adrb2,Trib1 |
| 2.240e-02 | -3.80 | GO_REGULATION_OF_FIBROBLAST_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_FIBROBLAST_PROLIFERATION | 79 | 12 | 15632 | 1249 |
Pdgfb,Myc,Jun,Dach1,Morc3,Pdgfc,Cdkn1a,Cd74,Sphk1,Parp10,Nupr1,Pml |
| 2.241e-02 | -3.80 | Prostate cancer | KEGG pathways | mmu05215 | 87 | 14 | 7931 | 713 |
Pik3cd,Map2k1,Cdkn1a,Pdgfrb,Ikbkg,Ccne1,Nfkbia,Ccnd1,Nfkb1,Akt3,Mdm2,Pdgfb,Pdgfc,Igf1r |
| 2.241e-02 | -3.80 | Prostate cancer | KEGG pathways | ko05215 | 87 | 14 | 7931 | 713 |
Nfkb1,Akt3,Mdm2,Igf1r,Pdgfb,Pdgfc,Pik3cd,Map2k1,Cdkn1a,Pdgfrb,Ccnd1,Ikbkg,Ccne1,Nfkbia |
| 2.249e-02 | -3.79 | SM22CALPONIN | prints domains | PR00888 | 10 | 3 | 5821 | 374 |
Cnn3,Tagln,Cnn2 |
| 2.251e-02 | -3.79 | transcriptional repressor complex | cellular component | GO:0017053 | 82 | 11 | 20747 | 1409 |
Jun,Hdac1,Etv3,Dr1,Ccnd1,Relb,Arid4a,Gfi1,Spen,Rbbp8,Sirt1 |
| 2.254e-02 | -3.79 | GCNP_SHH_UP_LATE.V1_UP | MSigDB lists | GCNP_SHH_UP_LATE.V1_UP | 165 | 21 | 15632 | 1249 |
Nxf1,Mcm6,Serpinb9,Zfp281,Ccnd2,Tmod3,Mcm10,Gbp2,Frmd6,Clcn5,Tnfsf10,Clic4,Cd80,Casp4,P2ry2,Higd1a,Plk2,Vcan,Sdc2,Trip13,Mdn1 |
| 2.254e-02 | -3.79 | GO_ACTIN_BASED_CELL_PROJECTION | MSigDB lists | GO_ACTIN_BASED_CELL_PROJECTION | 165 | 21 | 15632 | 1249 |
Pdpn,Antxr1,Syne2,Vasp,Itgav,Dync1h1,Ezr,Clic5,Slc4a7,Cd302,Dock4,Cnp,Myo1b,Acpp,Clic4,Osbpl3,Fscn1,Vcam1,Angpt1,Myo10,Spata13 |
| 2.255e-02 | -3.79 | JmjN | pfam domains | PF02375 | 9 | 3 | 18711 | 1348 |
Kdm5b,Kdm4a,Jarid2 |
| 2.255e-02 | -3.79 | DnaJ_C | pfam domains | PF01556 | 9 | 3 | 18711 | 1348 |
Dnajb4,Dnaja2,Dnaja1 |
| 2.255e-02 | -3.79 | Drf_FH3 | pfam domains | PF06367 | 9 | 3 | 18711 | 1348 |
Fmnl2,Daam1,Diaph2 |
| 2.255e-02 | -3.79 | PDGF | pfam domains | PF00341 | 9 | 3 | 18711 | 1348 |
Vegfc,Pdgfc,Pdgfb |
| 2.255e-02 | -3.79 | Drf_GBD | pfam domains | PF06371 | 9 | 3 | 18711 | 1348 |
Diaph2,Daam1,Fmnl2 |
| 2.258e-02 | -3.79 | GSE22886_NAIVE_CD8_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_DC_DN | 185 | 23 | 15632 | 1249 |
Gca,Tgfbi,Mthfd2,Snx2,Rapgef2,H2-Aa,Lap3,Slc7a8,Slc31a2,Ccr1,Txn1,Crim1,Cd83,Cd74,Hhex,Ap3b1,Nfkbie,Nqo1,Egr2,Rab11fip1,Dse,Cyfip1,Syk |
| 2.258e-02 | -3.79 | GSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | MSigDB lists | GSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | 185 | 23 | 15632 | 1249 |
Notch2,Igf1r,Abcc1,Tmem176a,Tyk2,Card6,Jdp2,Itgal,Cep350,Cd34,Sphk1,Nlrp3,Kcnj2,Gbp4,Gbp9,Cish,Kdm5b,Ccnd1,Rsad2,Cx3cr1,Bcl2l11,Itpr1,Zyx |
| 2.258e-02 | -3.79 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | 185 | 23 | 15632 | 1249 |
Nqo1,Slc39a4,Pde1b,Klf2,Fos,Traf2,Jun,Jarid2,Stat5a,Slc7a11,Plekha5,Abcc5,Plaur,1600014C10Rik,Dnajb4,Trim13,Nr4a3,Sema4a,Kif3c,Adrb2,Slco3a1,St3gal1,Mcoln2 |
| 2.258e-02 | -3.79 | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 185 | 23 | 15632 | 1249 |
Ext1,Ddit4,Egr2,Il18rap,Spsb1,Klf6,Plekhf2,Itgav,Slc16a3,Il10,Med21,Spred1,Aff1,Myo10,Lrrc8c,Atp10a,Casp7,Prnp,Slc43a3,Tab2,Cxcl10,Socs1,Ier3 |
| 2.258e-02 | -3.79 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP | 185 | 23 | 15632 | 1249 |
Ifit2,Casp8,Irf7,Map2k1,Lmo4,Rel,Tnfsf14,Dusp2,Tnfsf8,Mdn1,Zc3h7a,Oas2,Rasgrp1,Itga5,Oasl1,Nfkbiz,Ier2,Sell,Ms4a6d,Inpp1,Pilra,Gnb4,Klf7 |
| 2.260e-02 | -3.79 | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_UP | 175 | 22 | 15632 | 1249 |
Dusp5,Il12b,Kif3c,Il1rn,Tax1bp1,Inpp1,Igf1r,Clic5,Abtb2,Brd2,Nfkb1,Rel,Cnn3,Jag1,Casp2,Cd83,Traf5,Txnrd1,Ass1,Rbbp8,Hmga1,Gpr35 |
| 2.260e-02 | -3.79 | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_KO_DN | MSigDB lists | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_KO_DN | 175 | 22 | 15632 | 1249 |
Ldlr,Cflar,Nod1,Ap3m2,Prkar2b,Dio2,Rtn1,Usp31,Ptger4,Frmd4a,Scn1b,Igsf6,Zfp36,Myc,Ikzf1,Psma6,Ppp1r14b,Ccne1,4930523C07Rik,Abtb2,Slc7a8,Pdgfrb |
| 2.260e-02 | -3.79 | FERNANDEZ_BOUND_BY_MYC | MSigDB lists | FERNANDEZ_BOUND_BY_MYC | 175 | 22 | 15632 | 1249 |
Jun,Ets2,Casp8,Eno1,Serpine1,Acpp,Junb,Txn1,Met,Mdm2,Ampd3,Pla2g4a,Isg20,Icam1,Hif1a,Dck,Hmox1,Irf2,Cldnd1,Cxcl1,Arf4,Col4a2 |
| 2.260e-02 | -3.79 | ESC_J1_UP_LATE.V1_UP | MSigDB lists | ESC_J1_UP_LATE.V1_UP | 175 | 22 | 15632 | 1249 |
Dram1,Atf3,Cd55,Irs2,Grina,Bmp2,Col4a2,Tfec,Gng12,Crim1,P4ha1,Sesn3,P4ha2,Gadd45b,Cited2,Htra1,Phlda1,Oaf,Ctsc,Fut8,Tdrd7,Rhou |
| 2.260e-02 | -3.79 | GSE3982_DC_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_UP | 175 | 22 | 15632 | 1249 |
Ythdf1,Atp13a1,Cnot4,Arhgef3,P4ha2,Dtwd1,Kmo,Ccl22,Palld,Evl,Atf3,Rars,Ppp2r3a,Alas1,Lnpep,Osbpl3,Polr2g,Rab20,Tgfbi,Rcn1,Mtdh,Ptk2 |
| 2.260e-02 | -3.79 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_UP | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_UP | 175 | 22 | 15632 | 1249 |
Pml,Col18a1,Icam1,Cdc42ep2,Mdfic,Etv5,P4ha2,Aoah,Map3k6,Gadd45b,Rhof,Micall2,Arhgap26,Tlk2,Smc5,Smox,Il12b,Cflar,Plaur,Ccr1,Sema3c,Il12rb1 |
| 2.260e-02 | -3.79 | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 175 | 22 | 15632 | 1249 |
Gtpbp2,Arf4,Acvr1b,St3gal1,Dtx2,Spint2,Caml,Sap30,Cd164,Prpf38a,Atp11b,Prnp,Traf1,H2-Q7,Ube2e1,Scarf1,Setdb2,Itpr1,H2-Q6,Rbbp8,H2-Q4,Morc3 |
| 2.260e-02 | -3.79 | GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN | 175 | 22 | 15632 | 1249 |
P2ry12,Plekha2,P2ry13,Dync1h1,Ankib1,Cnn2,Syk,Nfkbie,Hivep3,Slamf9,Kctd12,Nr3c1,Trim14,Gpr35,Grina,Pik3cd,Ptk2,Aim2,Mark2,Rab3ip,Tnfaip3,Ciita |
| 2.260e-02 | -3.79 | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP | 175 | 22 | 15632 | 1249 |
Cd164,Aff1,Tle3,Dusp14,Ubash3b,Atf3,Pgs1,Acvr1,Spry2,D1Ertd622e,Arid5a,Mgat1,Dhrs9,Zcchc2,Trib1,Tnfsf15,Tnfsf14,Klf2,Rabgef1,Ccr1,Tshz1,Psd4 |
| 2.260e-02 | -3.79 | GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_UP | MSigDB lists | GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_UP | 175 | 22 | 15632 | 1249 |
Cd83,Dcbld2,Klf7,Gng12,Fam162a,Ppfibp1,Pgk1,Endod1,Marcksl1,Sema4c,Ebi3,Tpi1,Mapkapk2,Ptgir,Mthfd2,Cdc42ep4,Hivep3,Hk2,Ttc9c,Phldb1,Myo1b,Eno1 |
| 2.264e-02 | -3.79 | Generic Transcription Pathway | REACTOME pathways | R-MMU-212436 | 399 | 47 | 8608 | 757 |
Txnrd1,Tnks1bp1,Nr1h3,Notch1,Rbbp8,Cited2,Taf4b,Plk2,Mdm2,Btg2,Prdx1,Dek,Cenpj,Dyrk2,Tcea1,Polr2g,Rictor,Ccne1,Casp2,Notch2,Nr4a3,Txn1,Cdkn1a,Med13,Kat2b,Tpx2,Daxx,Nr3c1,Rbl1,Kmt5a,Rffl,Cdk5r1,Cnot4,Kdm5b,Gsr,Tmem219,Nr4a1,Ppp2r1b,Prdx5,Maml2,Atm,Ddit4,Rnf34,Top3a,Hdac1,Pml,Plk3 |
| 2.265e-02 | -3.79 | JANUSKINASE | prints domains | PR01823 | 4 | 2 | 5821 | 374 |
Jak2,Tyk2 |
| 2.265e-02 | -3.79 | CALPONIN | prints domains | PR00889 | 4 | 2 | 5821 | 374 |
Cnn2,Cnn3 |
| 2.265e-02 | -3.79 | MTVERTEBRATE | prints domains | PR00860 | 4 | 2 | 5821 | 374 |
Mt1,Mt2 |
| 2.265e-02 | -3.79 | ADSPHPHTASEB | prints domains | PR01910 | 4 | 2 | 5821 | 374 |
Dusp14,Dusp1 |
| 2.265e-02 | -3.79 | THFDHDRGNASE | prints domains | PR00085 | 4 | 2 | 5821 | 374 |
Mthfd1l,Mthfd2 |
| 2.265e-02 | -3.79 | LNOTCHREPEAT | prints domains | PR01452 | 4 | 2 | 5821 | 374 |
Notch2,Notch1 |
| 2.266e-02 | -3.79 | GO_CELL_JUNCTION | MSigDB lists | GO_CELL_JUNCTION | 1076 | 104 | 15632 | 1249 |
Agrn,Flrt3,Ezr,Flt1,Zyx,Cyfip1,Kcnj2,Triobp,Dmxl2,Rras2,Rnd3,Plau,Ppfibp1,Rims3,Layn,Flnb,Procr,Jag1,Cd200,Nox1,Kdr,Actb,Nlgn2,Clmp,Hspa1a,Slc2a1,Rgs14,Dbnl,Ccnd1,Itga4,Irf2,Ddx58,Icam1,Hck,Notch1,Nampt,Sipa1l1,Scn1b,Hap1,Smc5,Ptprj,Clic4,Hcar2,Plaur,Itgav,Cnn2,Hmga1,Mmp14,Palld,Nck1,Evl,Mpp7,Pikfyve,Dcp2,Sdc1,Sdc4,Lap3,Cav1,Vezt,Cnn3,Slc9a1,Fabp7,Rhou,Kctd12,Syne2,Itga5,Sema4c,Mtdh,Ptk2,Lyn,Pdzd11,Rap2c,Znrf1,Fscn1,Rpgrip1l,Frmd6,Homer1,Rab21,Micall2,Tnc,Tlk2,Arhgap26,Asap3,Rnd1,F11r,Csrp1,Gja1,Myadm,Igsf9,Pdgfrb,Map2k1,Fzd5,Flrt2,Lcp2,Pdlim7,Rab10,Fzd1,Vasp,Rapgef2,Mmp13,Frmd4a,Keap1,Htr2b,Pkp4 |
| 2.267e-02 | -3.79 | Cytosolic sensors of pathogen-associated DNA | REACTOME pathways | R-MMU-1834949 | 56 | 10 | 8608 | 757 |
Nfkb2,Nfkb1,Irf7,Nfkbia,Zbp1,Ikbkg,Nfkbib,Trim21,Myd88,Trim56 |
| 2.267e-02 | -3.79 | RAF activation | REACTOME pathways | R-MMU-5673000 | 26 | 6 | 8608 | 757 |
Ppp2r1b,Jak2,Map2k1,Src,Ppp2r5a,Ksr1 |
| 2.267e-02 | -3.79 | A tetrasaccharide linker sequence is required for GAG synthesis | REACTOME pathways | R-MMU-1971475 | 26 | 6 | 8608 | 757 |
Sdc1,Vcan,Agrn,Sdc2,Sdc4,Gpc1 |
| 2.273e-02 | -3.78 | GO_REGULATION_OF_ORGAN_MORPHOGENESIS | MSigDB lists | GO_REGULATION_OF_ORGAN_MORPHOGENESIS | 236 | 28 | 15632 | 1249 |
Znrf3,Psmb10,Psme1,Bcor,Pml,Lif,Notch1,Etv5,Tnfaip3,Plau,Cd34,Bmp2,Psmb9,Psmd10,Cited2,Tnf,Psma6,Edn1,Myc,Stat1,Psmb6,Sec24b,Fzd5,Daam1,Psmb8,Fzd1,Csf1,Psme2 |
| 2.273e-02 | -3.78 | GOZGIT_ESR1_TARGETS_UP | MSigDB lists | GOZGIT_ESR1_TARGETS_UP | 126 | 17 | 15632 | 1249 |
Dock10,Kctd12,Pcx,B4galt4,Fos,Ptpn2,Serpine1,Csf3r,Slc25a37,Prkar2b,Acsl5,Plcl2,Cacna1d,Pim1,Il18,Nr1h3,Ptger4 |
| 2.277e-02 | -3.78 | Serine biosynthesis, glycerate-3P => serine | KEGG pathways | M00020 | 3 | 2 | 7931 | 713 |
Phgdh,Psat1 |
| 2.277e-02 | -3.78 | Glutathione biosynthesis, glutamate => glutathione | KEGG pathways | M00118 | 3 | 2 | 7931 | 713 |
Gclm,Gclc |
| 2.277e-02 | -3.78 | Glutathione biosynthesis, glutamate => glutathione | KEGG pathways | mmu_M00118 | 3 | 2 | 7931 | 713 |
Gclm,Gclc |
| 2.277e-02 | -3.78 | Serine biosynthesis, glycerate-3P => serine | KEGG pathways | mmu_M00020 | 3 | 2 | 7931 | 713 |
Phgdh,Psat1 |
| 2.285e-02 | -3.78 | MODULE_239 | MSigDB lists | MODULE_239 | 107 | 15 | 15632 | 1249 |
Znfx1,Tor1aip1,Lnpep,Dync1h1,G3bp2,Ap3b1,Ppp2r5a,Tbc1d1,Slc30a1,Map3k8,Atp11a,Tmod3,Hmgcs1,Idi1,Lrp11 |
| 2.286e-02 | -3.78 | ETSDOMAIN | prints domains | PR00454 | 26 | 5 | 5821 | 374 |
Etv6,Spic,Ets2,Etv5,Etv3 |
| 2.291e-02 | -3.78 | MYO5A (myosin VA) | protein interactions | 4644 | 12 | 4 | 7778 | 753 |
Itga5,Actb,Flnb,Tmod3 |
| 2.291e-02 | -3.78 | PPP1CC (protein phosphatase 1 catalytic subunit gamma) | protein interactions | 5501 | 12 | 4 | 7778 | 753 |
Rrbp1,Flnb,Sass6,Ranbp2 |
| 2.291e-02 | -3.78 | DAB2 (DAB adaptor protein 2) | protein interactions | 1601 | 12 | 4 | 7778 | 753 |
Actb,Fcho2,Flnb,Tmod3 |
| 2.291e-02 | -3.78 | Stat5a (signal transducer and activator of transcription 5A) | protein interactions | 20850 | 12 | 4 | 7778 | 753 |
Jak2,Hdac1,Cenpj,Cish |
| 2.299e-02 | -3.77 | axon development | biological process | GO:0061564 | 375 | 36 | 20694 | 1406 |
Sema4a,Cnp,Evl,Lhx2,Nrp2,Sema3c,Jun,Vasp,Tnc,Egr2,Kif5c,Stxbp1,Cyfip1,Dst,Scn1b,Notch1,Agrn,Mark2,Ptk2,Palld,Actb,Itga4,Cdk5r1,Nr4a3,Rab10,Flrt2,Klf7,Uchl1,Jak2,Casp3,Flrt3,Tsku,Ptch1,Ntng2,Ext1,Igf1r |
| 2.301e-02 | -3.77 | GO_ZINC_ION_BINDING | MSigDB lists | GO_ZINC_ION_BINDING | 1008 | 98 | 15632 | 1249 |
Phf11c,Samhd1,Trim13,Tet2,Znfx1,Zyx,Zcchc2,Phf11d,Mefv,Oas1a,Rnf19a,Rasgrp1,Rabgef1,Ankib1,Birc3,Rnf31,Lnpep,Ubr4,Bfar,Pml,Ddx58,Kdm4a,Trim12c,Traf1,Dtx3l,Nr3c1,Setdb2,Top3a,Rffl,Kdm5b,Mdm2,Sp140,Apobec3,Birc2,Nfxl1,Tcea1,Sec24b,Rnf19b,Oas1g,Oas2,Gch1,Phf11a,Klf7,Znrf3,Pikfyve,Nr1h3,Mul1,Mmp14,Cnot4,Mllt6,Cpd,Mid1,Dtnb,Nr4a1,Trim36,Morc3,Rnf114,Sqstm1,Znrf1,Adam19,Lhx2,Dtx2,Mmp9,Rnf145,Mmp25,Zeb1,Trim14,Trim21,Trim56,Xaf1,S100a8,Rnf14,Lmo4,Rnf34,Traf5,Gda,Tnfaip3,Rnf139,Tab2,Ifih1,Rnf135,Micall2,Rnf24,Dhx58,Phf11b,Zswim4,Traf2,Sec24a,Sp110,Pcgf5,Phf6,Nr4a3,Trim26,Wdfy1,Pdlim7,Mmp13,Car13,Csrp1 |
| 2.317e-02 | -3.76 | response to fatty acid | biological process | GO:0070542 | 52 | 8 | 20694 | 1406 |
Ptger4,Zc3h12a,Pid1,Tlr2,Prkce,Tnfsf4,Pdk3,Ldlr |
| 2.317e-02 | -3.76 | intrinsic apoptotic signaling pathway by p53 class mediator | biological process | GO:0072332 | 52 | 8 | 20694 | 1406 |
Sirt1,Dyrk2,Nupr1,Ddit4,Ifi204,Cdkn1a,Pml,Pmaip1 |
| 2.324e-02 | -3.76 | GSE11818_WT_VS_DICER_KO_TREG_DN | MSigDB lists | GSE11818_WT_VS_DICER_KO_TREG_DN | 136 | 18 | 15632 | 1249 |
Herc3,Chd9,Ust,Gda,Prpf38a,Mtdh,Ptk2,Cd200,Rtp4,Xrn1,Sdc2,Stat4,Rsad2,Tor3a,Parp8,Ddhd1,Casp4,Irf7 |
| 2.327e-02 | -3.76 | WEST_ADRENOCORTICAL_TUMOR_UP | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_UP | 278 | 32 | 15632 | 1249 |
Mthfd2,Kif3c,Hmgcs1,Kpna3,Abcc1,Hsd17b7,Pde4b,Txn1,Slc31a2,Ccne1,Jag1,Tbc1d13,Slc7a5,Slc2a6,Pttg1,Tpx2,Fabp3,Rars,Stxbp1,Cd164,Tnfaip3,Col4a2,Extl2,Rnf34,Slc16a1,Homer1,Eno1,Dync1h1,P4ha2,Slc7a11,Hdac1,Atp13a1 |
| 2.333e-02 | -3.76 | ammonium ion metabolic process | biological process | GO:0097164 | 148 | 17 | 20694 | 1406 |
Sgms2,Srm,Plpp1,Pla2g7,Smox,Sphk1,Hdc,Pde1b,Mecp2,Gch1,Lpcat2,Asah2,Odc1,Cept1,Sat1,Degs2,Smpdl3b |
| 2.339e-02 | -3.76 | GO_ACTOMYOSIN | MSigDB lists | GO_ACTOMYOSIN | 53 | 9 | 15632 | 1249 |
Flnb,Pdlim7,Fscn1,Micall2,Cnn2,Ptk2,Zyx,Kat2b,Daam1 |
| 2.339e-02 | -3.76 | KANNAN_TP53_TARGETS_UP | MSigDB lists | KANNAN_TP53_TARGETS_UP | 53 | 9 | 15632 | 1249 |
Fas,Plk3,Atf3,Gdf15,Bcl6,Btg2,Vcan,Cdkn1a,Dgka |
| 2.339e-02 | -3.76 | GNF2_PTPN6 | MSigDB lists | GNF2_PTPN6 | 53 | 9 | 15632 | 1249 |
H2-Q7,H2-Q4,Sell,Lyn,H2-Q6,Hcls1,Crlf3,Tapbp,Sp110 |
| 2.339e-02 | -3.76 | BERNARD_PPAPDC1B_TARGETS_DN | MSigDB lists | BERNARD_PPAPDC1B_TARGETS_DN | 53 | 9 | 15632 | 1249 |
Ap3m2,Crim1,Thbs1,Cish,Sh3bgrl2,Rhof,Rcan1,Itgal,Kif5c |
| 2.339e-02 | -3.76 | ZHAN_MULTIPLE_MYELOMA_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_UP | 53 | 9 | 15632 | 1249 |
Atf3,Uchl1,Casp1,Cd200,Arid5a,Extl2,Cox17,Mvp,Cdkn1a |
| 2.344e-02 | -3.75 | peptide transport | biological process | GO:0015833 | 1251 | 103 | 20694 | 1406 |
Rilpl1,Arl4a,Rhbdf2,Nos2,Nxf1,Myo1b,Stat3,Aftph,Snx10,Hap1,Rrs1,Stx11,Sec24a,Rab19,Slco3a1,Nlrc4,Lcp2,Tlr6,Fam53c,Tlr2,Adar,Pou2f2,Optn,Tomm70a,Apba1,Plekhf2,Notch1,Nlrp3,Ranbp2,Chmp4b,Mcoln2,Kif5c,Ehd1,Rab11fip1,Fchsd2,Aim2,Ap3b1,Nfkbia,Arrdc4,Rab21,D1Ertd622e,Dio2,Stau1,Stx6,Edn1,Nod2,Tap2,Dennd1b,Svbp,Vps54,Dtx3l,Rab3ip,Rnf19b,Kpna3,Ap3m2,Il6,Cox18,Grk3,Plek,Trem1,Rab9,Rrbp1,Tbc1d13,Rab32,Itgav,Rtp4,Slc7a11,Slc15a3,Lyn,Spire1,Parp11,Arf4,Tap1,Isg15,Hhex,Syk,Ric1,Stxbp1,Egr2,Rffl,Snx2,Ift57,Arl5c,Serp1,Rab20,Rtn2,Pml,Cdkn1a,Abcc1,Arl5b,Phip,Dennd2a,Msr1,Stxbp3,Calcrl,Notch2,Rab10,Rabgef1,Tbc1d1,Ift22,Cd74,Il1rn,Traf3ip2 |
| 2.349e-02 | -3.75 | EGFL7 (EGF like domain multiple 7) | protein interactions | 51162 | 7 | 3 | 7778 | 753 |
Notch1,Notch2,Cenpe |
| 2.349e-02 | -3.75 | Mllt3 (myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3) | protein interactions | 70122 | 7 | 3 | 7778 | 753 |
Bcor,Hspa1b,Stip1 |
| 2.349e-02 | -3.75 | RPS3A (ribosomal protein S3A) | protein interactions | 6189 | 7 | 3 | 7778 | 753 |
Mdm2,Rrbp1,Ksr1 |
| 2.349e-02 | -3.75 | EMD (emerin) | protein interactions | 2010 | 7 | 3 | 7778 | 753 |
Ksr1,Ktn1,Cenpe |
| 2.349e-02 | -3.75 | ARPC5 (actin related protein 2/3 complex subunit 5) | protein interactions | 10092 | 7 | 3 | 7778 | 753 |
Itga5,Actb,Flnb |
| 2.349e-02 | -3.75 | DYNC1LI2 (dynein cytoplasmic 1 light intermediate chain 2) | protein interactions | 1783 | 7 | 3 | 7778 | 753 |
Dync1h1,Cenpe,Dync1i2 |
| 2.349e-02 | -3.75 | Cop1 (COP1, E3 ubiquitin ligase) | protein interactions | 26374 | 7 | 3 | 7778 | 753 |
Trib3,Trib1,Etv5 |
| 2.349e-02 | -3.75 | RPS9 (ribosomal protein S9) | protein interactions | 6203 | 7 | 3 | 7778 | 753 |
Mdm2,Rrbp1,Ksr1 |
| 2.349e-02 | -3.75 | ABCD3 (ATP binding cassette subfamily D member 3) | protein interactions | 5825 | 7 | 3 | 7778 | 753 |
Ktn1,Chmp4b,Rmdn3 |
| 2.349e-02 | -3.75 | Arhgdia (Rho GDP dissociation inhibitor (GDI) alpha) | protein interactions | 192662 | 7 | 3 | 7778 | 753 |
Ikbkg,Casp7,Casp3 |
| 2.349e-02 | -3.75 | Trim59 (tripartite motif-containing 59) | protein interactions | 66949 | 7 | 3 | 7778 | 753 |
Cd74,Plscr1,Triobp |
| 2.349e-02 | -3.75 | Irf5 (interferon regulatory factor 5) | protein interactions | 27056 | 7 | 3 | 7778 | 753 |
Peli1,Myd88,Il12b |
| 2.349e-02 | -3.75 | DNAJB1 (DnaJ heat shock protein family (Hsp40) member B1) | protein interactions | 3337 | 7 | 3 | 7778 | 753 |
Hsph1,4932438A13Rik,Ksr1 |
| 2.349e-02 | -3.75 | LIMCH1 (LIM and calponin homology domains 1) | protein interactions | 22998 | 7 | 3 | 7778 | 753 |
Kif3c,Itga5,Actb |
| 2.349e-02 | -3.75 | DYNC1LI1 (dynein cytoplasmic 1 light intermediate chain 1) | protein interactions | 51143 | 7 | 3 | 7778 | 753 |
Dync1h1,Cenpe,Dync1i2 |
| 2.349e-02 | -3.75 | Nfkb2 (nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100) | protein interactions | 18034 | 7 | 3 | 7778 | 753 |
Relb,Nfkb1,Nfkbiz |
| 2.349e-02 | -3.75 | MYBBP1A (MYB binding protein 1a) | protein interactions | 10514 | 7 | 3 | 7778 | 753 |
Ktn1,Ksr1,Rrbp1 |
| 2.349e-02 | -3.75 | EEF1D (eukaryotic translation elongation factor 1 delta) | protein interactions | 1936 | 7 | 3 | 7778 | 753 |
Rrbp1,Cenpe,Ktn1 |
| 2.349e-02 | -3.75 | RPL7A (ribosomal protein L7a) | protein interactions | 6130 | 7 | 3 | 7778 | 753 |
Ksr1,Rrbp1,Ktn1 |
| 2.350e-02 | -3.75 | regulation of pathway-restricted SMAD protein phosphorylation | biological process | GO:0060393 | 62 | 9 | 20694 | 1406 |
Acvr1,Pmepa1,Bmp2,Lgals9,Inhba,Acvr1b,Acvrl1,Rbpms,Gdf15 |
| 2.355e-02 | -3.75 | eye morphogenesis | biological process | GO:0048592 | 171 | 19 | 20694 | 1406 |
Slc4a7,Fzd5,Stat3,Ikzf1,Prdm1,Zeb1,Ppp2r3a,Tsku,Flt1,Kdr,Casz1,Hif1a,Cited2,Tdrd7,Phactr4,Pdgfb,Jag1,Notch2,Zhx2 |
| 2.356e-02 | -3.75 | WANG_HCP_PROSTATE_CANCER | MSigDB lists | WANG_HCP_PROSTATE_CANCER | 98 | 14 | 15632 | 1249 |
Cited2,Fubp1,Ppp1r15a,Ass1,Dusp1,Nampt,Gadd45b,Htra1,Nr3c1,St3gal6,Atf3,Cd55,Dnajb2,Aff1 |
| 2.356e-02 | -3.75 | MODULE_129 | MSigDB lists | MODULE_129 | 206 | 25 | 15632 | 1249 |
B4galt4,Tpst1,P4ha2,Gadd45g,Tnc,Papss2,Etv5,Myo10,Bmp2,Gng11,Ifit3,Marco,Rgl1,Slc7a8,Mmp13,Oas1a,Syne2,Fzd1,Bcl9,Ifit3b,St3gal1,Rac3,Filip1l,Oas1g,Dnajb2 |
| 2.360e-02 | -3.75 | GO_REGULATION_OF_ACTIN_FILAMENT_LENGTH | MSigDB lists | GO_REGULATION_OF_ACTIN_FILAMENT_LENGTH | 146 | 19 | 15632 | 1249 |
Prkce,Rictor,Csf3,Vasp,Triobp,Plek,Myadm,Swap70,Cyfip1,Whamm,Cdc42ep2,Hcls1,Hck,Evl,Nck1,Tmod3,Icam1,Spire1,Cdc42ep4 |
| 2.372e-02 | -3.74 | KRAS.LUNG_UP.V1_UP | MSigDB lists | KRAS.LUNG_UP.V1_UP | 117 | 16 | 15632 | 1249 |
Csf3,Inhba,Bcl2a1d,Ikzf1,Abcb1a,Dock4,Cx3cr1,Bcl2a1b,Dcbld2,Bcl2a1a,Cd80,Fbxo4,St3gal6,Fabp3,Tmem176b,Kif5c |
| 2.372e-02 | -3.74 | AA/rel_permease1 | interpro domains | IPR002293 | 16 | 4 | 19984 | 1430 |
Slc7a5,Slc7a2,Slc7a11,Slc7a8 |
| 2.375e-02 | -3.74 | HALLMARK_XENOBIOTIC_METABOLISM | MSigDB lists | HALLMARK_XENOBIOTIC_METABOLISM | 196 | 24 | 15632 | 1249 |
Gcnt2,Gsta3,Ptges,Acp2,Smox,Hmox1,Alas1,Spint2,Gch1,Irf8,Serpine1,F10,Gclc,Tmem176b,Fas,Upp1,Arg2,Psmb10,Papss2,Pcx,Gsr,Nqo1,Ets2,Tpst1 |
| 2.375e-02 | -3.74 | GO_TRANSCRIPTION_COREPRESSOR_ACTIVITY | MSigDB lists | GO_TRANSCRIPTION_COREPRESSOR_ACTIVITY | 196 | 24 | 15632 | 1249 |
Sirt1,Zeb1,Sap30,Cdyl,Junb,Nfil3,Zhx2,Tfec,Dr1,Trib3,Aebp2,Hdac1,Kdm5b,Mecp2,Ccnd1,Eno1,Rbbp8,Cited2,Daxx,Relb,Zfp281,Atf3,Mxd1,Bcor |
| 2.379e-02 | -3.74 | - | gene3d domains | 1.20.1560.10 | 20 | 5 | 8819 | 755 |
Tap2,Abcc5,Abcc4,Tap1,Abcc1 |
| 2.382e-02 | -3.74 | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP | MSigDB lists | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP | 156 | 20 | 15632 | 1249 |
Rab3ip,Rras2,Znrf1,Crlf3,Calcrl,Sell,Evl,Bcor,Sele,Kdm5b,Treml2,Akt3,Peli1,Myc,Tlr1,Parp8,Arid4a,Klf3,Sesn3,Card6 |
| 2.388e-02 | -3.73 | HNF4ALPHA_Q6 | MSigDB lists | HNF4ALPHA_Q6 | 237 | 28 | 15632 | 1249 |
N4bp1,Cited2,Rbpms,Hhex,Prdm1,Abr,Nek6,Csrnp1,Plagl1,Cdk5r1,Ccdc88b,Clcn5,Mark2,Ccr1,Brwd3,Pid1,Slc9a1,Pdgfb,Rtn2,Timeless,Hat1,Dnaja2,Nr4a3,Gpr85,Pcdh7,Rbms1,Sec24b,Pmepa1 |
| 2.389e-02 | -3.73 | GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | 186 | 23 | 15632 | 1249 |
Fam72a,Btg2,Map2k1,Ifit3,Myadm,Ifit1bl2,Ifit3b,Adrb2,Mthfd2,Ppa1,Usp31,Kpna3,Nat2,Fchsd2,Gpr18,Ifit1bl1,Ahr,Ncoa7,Cd83,Rtp4,Ppm1l,Mpp7,Rars |
| 2.389e-02 | -3.73 | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_UP | MSigDB lists | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_UP | 186 | 23 | 15632 | 1249 |
Sap30,D1Ertd622e,Fut8,Peli1,St3gal5,Cox17,Cebpd,Gch1,Myadm,Txnrd1,Nfkb1,Sqstm1,Cd83,Il15,Prdx1,Dr1,Cd14,Dusp16,Nfkbiz,Mtdh,Zfp281,Calcrl,Clec4d |
| 2.389e-02 | -3.73 | GO_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS | 186 | 23 | 15632 | 1249 |
Pml,Usp25,Kdm4a,Tab2,Pde3b,Tspo,Atp2b4,Chmp4b,Irak3,Tnf,N4bp1,Timp1,Stat3,Tlk2,Hp,Htr2b,Il1b,Hcar2,Atm,Il10,Nos2,Ddit4,Met |
| 2.389e-02 | -3.73 | protein phosphatase regulator activity | molecular function | GO:0019888 | 71 | 10 | 20217 | 1400 |
Ppp1r15b,Phactr4,Ppp2r1b,Rcan1,Ppp1r15a,Ppp2r2a,Ppp1r14b,Ppp2r3a,Ppp4r2,Ppp2r5a |
| 2.393e-02 | -3.73 | GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_DN | 166 | 21 | 15632 | 1249 |
Frmd6,Gbp2,Keap1,Rhoc,Nfxl1,Cd82,Trib3,Rab20,Ebi3,Stxbp1,Egln3,Spint2,Ddit4,Irf4,Gna15,Cenpj,Layn,Trip10,Map2k1,Plac8,P4ha1 |
| 2.395e-02 | -3.73 | GSE3982_BASOPHIL_VS_TH1_UP | MSigDB lists | GSE3982_BASOPHIL_VS_TH1_UP | 176 | 22 | 15632 | 1249 |
Usp25,Rnf139,Hp,Mxd1,Map2k4,P2ry14,Fgr,Osgin2,Plagl1,Hck,Cd164,Pdgfc,Plekhf2,Dpy19l1,Dusp1,Atm,Bcl6,P2ry13,Dse,Swap70,Ppp2r5a,Spen |
| 2.395e-02 | -3.73 | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP | 176 | 22 | 15632 | 1249 |
Igsf6,Dusp2,Cnn2,Plac8,Tpst1,Extl2,Il15,Tap1,Prdm1,Spata13,Ifih1,Fabp3,Rtp4,Nrp2,Icosl,Smpdl3b,Oas1a,Parp12,Jarid2,Psmb8,Ap3m2,Oas1g |
| 2.395e-02 | -3.73 | GSE27786_BCELL_VS_CD8_TCELL_DN | MSigDB lists | GSE27786_BCELL_VS_CD8_TCELL_DN | 176 | 22 | 15632 | 1249 |
Znrf1,Enpp4,Ifit1,Dio2,Smox,Atp10a,Cox18,Dnajb4,Mppe1,Il4ra,Mpp7,Reps1,Ppp4r2,Slc39a4,Rnf19a,Dock10,Mthfd1l,Klf3,Hk1,Itgal,Gbp7,Casp8 |
| 2.395e-02 | -3.73 | GSE24210_RESTING_TREG_VS_TCONV_DN | MSigDB lists | GSE24210_RESTING_TREG_VS_TCONV_DN | 176 | 22 | 15632 | 1249 |
Gsr,Nqo1,Psma6,Oaf,Srm,Axl,Ahsa1,Prdx1,Pttg1,Lrp8,Hat1,Car13,Hivep3,Slc7a5,Casp4,Il10,Abcc4,Esd,Fam162a,Ccl4,Dgkh,Hmgcs1 |
| 2.395e-02 | -3.73 | BILD_MYC_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_MYC_ONCOGENIC_SIGNATURE | 176 | 22 | 15632 | 1249 |
Hk2,Dgka,Pdlim7,Ltbp2,Rcl1,Nfkb2,Tnfaip2,Cflar,Triobp,Pcx,Ccng2,Taf4b,Myc,Ccdc86,Dusp2,Srm,Map3k6,Atp2b4,Pnpt1,Plau,Aldh1b1,Mcoln2 |
| 2.395e-02 | -3.73 | AAANWWTGC_UNKNOWN | MSigDB lists | AAANWWTGC_UNKNOWN | 176 | 22 | 15632 | 1249 |
Cacna1d,Actb,Ppp2r2a,Lox,Rab10,Atxn7l1,Inhba,Rrs1,Pdgfrb,Cd14,Lipg,Atp2b4,Hhex,Nek6,Dtx3l,Cept1,Mllt6,Mid1,Adhfe1,Dusp1,Bcl6,Cited2 |
| 2.395e-02 | -3.73 | GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN | MSigDB lists | GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN | 176 | 22 | 15632 | 1249 |
Klf2,Bcl2a1b,Apobec3,Bcl2a1d,Xaf1,Zfp36,Gpr35,Ppp4r2,Bcl9,Irgm2,Mefv,Phip,Sdc1,Rnf139,Hmox1,Marcksl1,Itga4,Tfec,Clcn5,Bcl2a1a,Pilra,Sgk3 |
| 2.397e-02 | -3.73 | Cell cycle - G1/S transition | KEGG pathways | mmu_M00692 | 13 | 4 | 7931 | 713 |
Ccnd2,Ccne1,Rbl1,Ccnd1 |
| 2.397e-02 | -3.73 | Cell cycle - G1/S transition | KEGG pathways | M00692 | 13 | 4 | 7931 | 713 |
Ccnd2,Rbl1,Ccnd1,Ccne1 |
| 2.401e-02 | -3.73 | regulation of protein complex disassembly | biological process | GO:0043244 | 115 | 14 | 20694 | 1406 |
Carmil1,Irgm2,Tnf,Mid1,Tmod3,Dbnl,Igf1r,Irak3,Bnip3,Evl,Adrb2,Irgm1,Swap70,Plek |
| 2.405e-02 | -3.73 | transferase complex, transferring phosphorus-containing groups | cellular component | GO:0061695 | 242 | 25 | 20747 | 1409 |
Cdkn1a,Pik3r6,Socs7,Igf1r,Acvr1b,Acvrl1,Pik3cd,Acvr1,Ikbkg,Ccnd1,Znfx1,Ccnd2,Pik3r5,Taf4b,Socs1,Ccne1,Cdkn2d,Socs3,Ccnj,Cdk5r1,Pfkl,Polr2g,Cish,Ccng2,Tcea1 |
| 2.412e-02 | -3.72 | Death_domain | interpro domains | IPR000488 | 32 | 6 | 19984 | 1430 |
Fas,Nfkb1,Irak3,Myd88,Irak2,Nfkb2 |
| 2.412e-02 | -3.72 | JmjC_dom | interpro domains | IPR003347 | 32 | 6 | 19984 | 1430 |
Jmjd6,Kdm5b,Kdm6b,Riox2,Jarid2,Kdm4a |
| 2.414e-02 | -3.72 | HAHTOLA_SEZARY_SYNDROM_UP | MSigDB lists | HAHTOLA_SEZARY_SYNDROM_UP | 89 | 13 | 15632 | 1249 |
Samsn1,Slc25a37,Hat1,Pnp2,Tlr1,Pttg1,Trib1,Stat1,Mmp9,Hp,Cd55,Fas,Tnfsf10 |
| 2.424e-02 | -3.72 | regulation of ion transmembrane transport | biological process | GO:0034765 | 477 | 44 | 20694 | 1406 |
Gem,Glrx,Hap1,Kcnj2,Stoml1,Ccl2,Gpr35,Prnp,Cacnb3,Tlr9,Slc30a1,Adrb2,Thbs1,Slc9a1,Cox17,Tnf,Cx3cl1,Cacna1d,Kcna3,Ptafr,Cxcl10,Ubash3b,Atp2b4,Abcb1a,Scn1b,Clic5,Agrn,Acsl5,Mmp9,Pde4b,Hk1,Prkce,Slc31a2,Ahr,Irs2,Lyn,Cav1,Hvcn1,Homer1,Gja1,Crbn,Nlgn2,Clic4,Hspa2 |
| 2.425e-02 | -3.72 | AA_permease_2 | pfam domains | PF13520 | 16 | 4 | 18711 | 1348 |
Slc7a5,Slc7a8,Slc7a11,Slc7a2 |
| 2.426e-02 | -3.72 | FCH | smart domains | SM00055 | 20 | 5 | 9567 | 823 |
Trip10,Pstpip2,Fcho2,Fnbp1l,Fchsd2 |
| 2.427e-02 | -3.72 | GO_REGULATION_OF_PHAGOCYTOSIS | MSigDB lists | GO_REGULATION_OF_PHAGOCYTOSIS | 62 | 10 | 15632 | 1249 |
Stap1,Il1b,Hck,Itgav,Ccl12,C3,Syk,Tnf,Abr,Fgr |
| 2.427e-02 | -3.72 | RIZKI_TUMOR_INVASIVENESS_2D_UP | MSigDB lists | RIZKI_TUMOR_INVASIVENESS_2D_UP | 62 | 10 | 15632 | 1249 |
Klf2,Csf3r,Stat5a,H3f3b,Acvr1,Mllt6,Tmeff1,Dusp2,Adar,Idi1 |
| 2.430e-02 | -3.72 | TPR-contain_dom | interpro domains | IPR013026 | 120 | 15 | 19984 | 1430 |
Naa25,Tomm70a,Ifit3,Ranbp2,P4ha1,Gpsm2,Ttc9c,Ifit2,Ifit1bl1,Ifit1,Ifit1bl2,Tmtc2,Ifit3b,P4ha2,Stip1 |
| 2.430e-02 | -3.72 | Growth hormone receptor signaling | REACTOME pathways | R-MMU-982772 | 41 | 8 | 8608 | 757 |
Cish,Stat3,Socs1,Socs3,Stat1,Stat5a,Jak2,Lyn |
| 2.441e-02 | -3.71 | leukocyte degranulation | biological process | GO:0043299 | 25 | 5 | 20694 | 1406 |
Lyn,Milr1,Rasgrp1,Nr4a3,Stx11 |
| 2.441e-02 | -3.71 | protein refolding | biological process | GO:0042026 | 25 | 5 | 20694 | 1406 |
Hspa1b,Dnaja2,Hspa1a,Dnajb2,Hspa2 |
| 2.441e-02 | -3.71 | positive regulation of sterol transport | biological process | GO:0032373 | 25 | 5 | 20694 | 1406 |
Lipg,Nfkbia,Ptch1,Nr1h3,Sirt1 |
| 2.441e-02 | -3.71 | lymphocyte apoptotic process | biological process | GO:0070227 | 25 | 5 | 20694 | 1406 |
Crkl,Myc,Bcl2l11,Fas,Traf3ip2 |
| 2.441e-02 | -3.71 | regulation of cytoplasmic transport | biological process | GO:1903649 | 25 | 5 | 20694 | 1406 |
Ezr,Rab21,Mecp2,Src,Map2k1 |
| 2.441e-02 | -3.71 | cerebral cortex radial glia guided migration | biological process | GO:0021801 | 25 | 5 | 20694 | 1406 |
Lrp8,Cdk5r1,Syne2,Socs7,P2ry12 |
| 2.441e-02 | -3.71 | positive regulation of cholesterol transport | biological process | GO:0032376 | 25 | 5 | 20694 | 1406 |
Nr1h3,Sirt1,Ptch1,Nfkbia,Lipg |
| 2.441e-02 | -3.71 | telencephalon glial cell migration | biological process | GO:0022030 | 25 | 5 | 20694 | 1406 |
Lrp8,Cdk5r1,Socs7,Syne2,P2ry12 |
| 2.441e-02 | -3.71 | positive regulation of signal transduction by p53 class mediator | biological process | GO:1901798 | 25 | 5 | 20694 | 1406 |
Spred3,Atm,Pmaip1,Eef1e1,Spred1 |
| 2.451e-02 | -3.71 | GAVIN_FOXP3_TARGETS_CLUSTER_P7 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P7 | 80 | 12 | 15632 | 1249 |
Snn,Glipr2,Ncoa7,Agpat4,Mxd1,St3gal6,Ttc39b,Jun,Cyfip1,Prnp,Fos,Il10 |
| 2.456e-02 | -3.71 | SOX9_B1 | MSigDB lists | SOX9_B1 | 217 | 26 | 15632 | 1249 |
Mllt6,Klf3,Nr4a1,Parp8,Flrt3,Bcl2l11,N4bp1,Dock4,Pbx1,Rgs3,Hhex,Apba1,Usp25,Tmeff1,Slc39a14,G3bp2,Inhba,Dgka,Ccnj,Dusp6,Map4k4,Daam1,Arf4,Dnaja2,Rcn1,Adrb2 |
| 2.456e-02 | -3.71 | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 364 | 40 | 15632 | 1249 |
Nlgn2,Fscn1,Kdr,Lpar1,Cdc42ep4,Spire1,Ptprj,Csf3,Rictor,Hap1,Vasp,Piezo1,Cav1,Flrt2,Irf8,Plek,Atm,Hck,Sdc4,Cdc42ep2,Sdc1,Icam1,Mpp7,Nck1,Fas,Aim2,Evl,Tlr6,Mecp2,Edn1,Rhoq,Prkce,Swap70,Jun,Src,Tnf,Bcl2l11,Agrn,Flrt3,Phldb1 |
| 2.459e-02 | -3.71 | GO_RECEPTOR_METABOLIC_PROCESS | MSigDB lists | GO_RECEPTOR_METABOLIC_PROCESS | 71 | 11 | 15632 | 1249 |
Scyl2,Znrf3,Calcrl,Htr2b,Syk,Tnf,Ezr,Cav1,Il10,Fut8,Caml |
| 2.459e-02 | -3.71 | GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING | 71 | 11 | 15632 | 1249 |
Csf3,Rapgef2,Bambi,Bmp2,Plcl2,Cav1,Traf2,Trib3,Plk2,Mmp9,Crbn |
| 2.459e-02 | -3.71 | URS_ADIPOCYTE_DIFFERENTIATION_UP | MSigDB lists | URS_ADIPOCYTE_DIFFERENTIATION_UP | 71 | 11 | 15632 | 1249 |
Lrp8,Adora2b,Acsl1,Pfkfb3,Pcdh7,Tnfaip2,Tap1,Plek,Lipe,Mtus1,Fabp7 |
| 2.462e-02 | -3.70 | REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 | MSigDB lists | REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 | 45 | 8 | 15632 | 1249 |
Psmb10,Psmd10,Psmb9,Psmb6,Psmb8,Psme1,Psma6,Psme2 |
| 2.462e-02 | -3.70 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | MSigDB lists | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | 45 | 8 | 15632 | 1249 |
Egr2,Egr3,Src,Crkl,Egr1,Jun,Map2k4,Pik3cd |
| 2.462e-02 | -3.70 | DOANE_BREAST_CANCER_ESR1_DN | MSigDB lists | DOANE_BREAST_CANCER_ESR1_DN | 45 | 8 | 15632 | 1249 |
Upp1,S100a8,Psat1,Ass1,Sod2,Mid1,Fabp7,Slpi |
| 2.462e-02 | -3.70 | MAYBURD_RESPONSE_TO_L663536_DN | MSigDB lists | MAYBURD_RESPONSE_TO_L663536_DN | 45 | 8 | 15632 | 1249 |
Ccng2,Cycs,Actb,Plscr1,Med21,Ezr,Snx10,Ifnar1 |
| 2.462e-02 | -3.70 | GO_LUNG_MORPHOGENESIS | MSigDB lists | GO_LUNG_MORPHOGENESIS | 45 | 8 | 15632 | 1249 |
Plod3,Lif,Hhex,Map2k1,Spry2,Tnc,Stk40,Sec24b |
| 2.462e-02 | -3.70 | GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | 45 | 8 | 15632 | 1249 |
Myc,Tlr3,Lyn,Gpr68,Ptpn2,Inhba,Ubash3b,Trib1 |
| 2.464e-02 | -3.70 | leading edge membrane | cellular component | GO:0031256 | 149 | 17 | 20747 | 1409 |
Psd4,Pdpn,Ddx58,Arf4,Fgr,Spata13,Src,Ptprj,Itga5,Scimp,Syne2,Psd,Plek,Cacna1d,Adora2a,Antxr1,Itgav |
| 2.465e-02 | -3.70 | AP1_Q4 | MSigDB lists | AP1_Q4 | 248 | 29 | 15632 | 1249 |
Cdkn1a,Col27a1,Il1rn,Trib1,Mmp9,Pim2,Dtx2,Rap1gap2,Adora2a,Atxn7l1,Akt3,Isg20,Map2k1,Pdgfrb,Il10,Txn1,Etv5,Bmp2,Arrdc4,Ccl22,Nek6,Prdm1,Stk40,Il6,Bnip3,Edn1,Cyfip1,Znfx1,Ass1 |
| 2.467e-02 | -3.70 | inner ear auditory receptor cell differentiation | biological process | GO:0042491 | 43 | 7 | 20694 | 1406 |
Gfi1,Jag1,Notch1,Clic5,Sec24b,Triobp,Slc4a7 |
| 2.467e-02 | -3.70 | positive regulation of glucose metabolic process | biological process | GO:0010907 | 43 | 7 | 20694 | 1406 |
Ptpn2,Src,Dyrk2,Sirt1,Hif1a,Irs2,Kat2b |
| 2.467e-02 | -3.70 | eye development | biological process | GO:0001654 | 377 | 36 | 20694 | 1406 |
Tdrd7,Clic4,Tsku,Gja1,Jmjd6,Notch2,Zhx2,Inhba,Rcn1,Ahr,Rpgrip1l,Fzd5,Slc4a7,Pdgfrb,Ppp2r3a,Zeb1,Tulp3,Phactr4,Pdgfb,Cited2,Lif,Slc25a25,Casz1,Hif1a,Kdr,Flt1,Jun,Jag1,Gpd2,Prdm1,Lhx2,Hdac1,Ikzf1,Stat3,Acvrl1,Zfp513 |
| 2.471e-02 | -3.70 | SPTAN1 (spectrin alpha, non-erythrocytic 1) | protein interactions | 6709 | 18 | 5 | 7778 | 753 |
Timeless,Flnb,Tpx2,Tmod3,Actb |
| 2.471e-02 | -3.70 | Sos1 (SOS Ras/Rac guanine nucleotide exchange factor 1) | protein interactions | 20662 | 18 | 5 | 7778 | 753 |
Crkl,Fgr,Spry2,Src,Nck1 |
| 2.471e-02 | -3.70 | CCR4-NOT complex | cellular component | GO:0030014 | 17 | 4 | 20747 | 1409 |
Tnks1bp1,Zfp36,Cnot4,Noct |
| 2.475e-02 | -3.70 | positive regulation of cell size | biological process | GO:0045793 | 17 | 4 | 20694 | 1406 |
Akt3,Ahr,Edn1,Tmem123 |
| 2.475e-02 | -3.70 | regulation of interferon-gamma secretion | biological process | GO:1902713 | 17 | 4 | 20694 | 1406 |
Lgals9,Arid5a,Rasgrp1,Zc3h12a |
| 2.475e-02 | -3.70 | interleukin-1-mediated signaling pathway | biological process | GO:0070498 | 17 | 4 | 20694 | 1406 |
Irak3,Irak2,Il1a,Egr1 |
| 2.475e-02 | -3.70 | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902176 | 17 | 4 | 20694 | 1406 |
Hif1a,Sirt1,Sod2,Hsph1 |
| 2.475e-02 | -3.70 | negative regulation of multicellular organism growth | biological process | GO:0040015 | 17 | 4 | 20694 | 1406 |
Ptch1,Gdf15,Adrb2,Plac8 |
| 2.475e-02 | -3.70 | regulation of acute inflammatory response to antigenic stimulus | biological process | GO:0002864 | 17 | 4 | 20694 | 1406 |
C3,Spn,Fcgr1,Fcgr2b |
| 2.475e-02 | -3.70 | negative regulation of insulin secretion involved in cellular response to glucose stimulus | biological process | GO:0061179 | 17 | 4 | 20694 | 1406 |
Pde3b,Map4k4,Klf7,Pim3 |
| 2.475e-02 | -3.70 | regulation of B cell receptor signaling pathway | biological process | GO:0050855 | 17 | 4 | 20694 | 1406 |
Plcl2,Lyn,Fcgr2b,Stap1 |
| 2.475e-02 | -3.70 | activation of phospholipase C activity | biological process | GO:0007202 | 17 | 4 | 20694 | 1406 |
Htr2b,Htr2a,Sele,Lpar1 |
| 2.475e-02 | -3.70 | positive regulation of icosanoid secretion | biological process | GO:0032305 | 17 | 4 | 20694 | 1406 |
Il1a,P2ry2,Edn1,Il1b |
| 2.475e-02 | -3.70 | positive regulation of phosphoprotein phosphatase activity | biological process | GO:0032516 | 17 | 4 | 20694 | 1406 |
Ppp1r15b,Pdgfrb,Jak2,Ppp1r15a |
| 2.475e-02 | -3.70 | multi-organism cellular process | biological process | GO:0044764 | 17 | 4 | 20694 | 1406 |
Ddx58,Nectin2,Fchsd2,Ifih1 |
| 2.475e-02 | -3.70 | mast cell mediated immunity | biological process | GO:0002448 | 17 | 4 | 20694 | 1406 |
Milr1,Lyn,Nr4a3,Rasgrp1 |
| 2.475e-02 | -3.70 | 3'-UTR-mediated mRNA destabilization | biological process | GO:0061158 | 17 | 4 | 20694 | 1406 |
Zfp36,Zc3h12a,Plekhn1,Mov10 |
| 2.475e-02 | -3.70 | vascular smooth muscle contraction | biological process | GO:0014829 | 17 | 4 | 20694 | 1406 |
Htr2a,Cd38,Ednrb,Edn1 |
| 2.475e-02 | -3.70 | positive regulation of lymphocyte chemotaxis | biological process | GO:0140131 | 17 | 4 | 20694 | 1406 |
Ccl4,Ccl5,Cxcl14,Tnfsf14 |
| 2.476e-02 | -3.70 | GO_SMALL_MOLECULE_METABOLIC_PROCESS | MSigDB lists | GO_SMALL_MOLECULE_METABOLIC_PROCESS | 1602 | 149 | 15632 | 1249 |
Tpi1,Papss2,Irs2,Aldh1b1,Pgm1,Slc16a1,Gpc1,Lpcat2,Extl2,Me1,Enpp4,Hk3,Ass1,Dhrs9,Syk,B4galt4,Gclm,Pla2g4a,Scarf1,Pde5a,Pcx,Cept1,Vcan,C3,Hmgcs1,Pdzd11,Mthfd2,Odc1,Ldlr,Idi1,Ust,Gfpt1,Abcc1,Hsd17b7,Hk1,Nos2,Hdc,Egln3,Ch25h,Arg2,Fabp3,Kmo,Upp1,Cd74,Gda,Slc16a3,Txnrd1,Tnf,Stat5a,Serp1,Phgdh,Cycs,Prdx5,Mecp2,St3gal1,Nr4a3,Phyh,Inpp1,Pgk1,Htr2b,Keap1,Il1b,Ptges,Ccl5,Pde4b,Hsd17b12,Asns,Ext1,Pde7b,Degs2,Car13,Slc25a12,Mapkapk2,St3gal3,Atf3,Rars,Sgms2,Nmral1,Pde3b,Gclc,Slc25a25,Pfkfb3,Samhd1,Angpt1,Adhfe1,Tet2,Slc44a1,Pdpn,Il4i1,Edn1,Chst11,Dck,Ppa1,Itpkc,Tnfsf4,Nox1,Acsl1,Gpd2,Prkar2b,Esd,Pfkl,P4ha1,Psat1,Eno2,Pdk3,Pdss1,Ampd3,Eef1e1,Smpdl3b,Oas1a,Mthfr,St3gal6,Sphk1,Calcrl,Hif1a,Lipe,Eno1,Hspa1a,Slc2a1,Dse,Acpp,Pde1b,Rhoq,Pnp2,Minpp1,Fut8,Gsr,Oas1g,Ldha,Ptafr,Ak4,Ptgs2,Acsl5,Cmpk2,Glrx,Gch1,Mthfd1l,Slc7a8,Nampt,Txn1,Slc7a2,Cnp,Ppm1k,Slc7a5,Inpp5b,Hk2,Adora2a,Oas2,Wars |
| 2.479e-02 | -3.70 | IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN | MSigDB lists | IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN | 311 | 35 | 15632 | 1249 |
N4bp1,Ppp1r14b,Klf6,Ifit2,Jun,Tmem184b,Irgq,Minpp1,Abcb1a,Cycs,Lrp8,Prdm1,Sell,Calcrl,Cyth3,Dcp2,Gnb4,Pfkfb3,Klf7,Hk1,Abtb2,Eif4g2,Plod2,Daam1,Irf8,Rictor,H2-Ab1,Gpd2,Il2rg,Chic2,Ms4a6d,Rcn1,Tax1bp1,Ppp2r1b,Kitl |
| 2.482e-02 | -3.70 | PID_EPHRINB_REV_PATHWAY | MSigDB lists | PID_EPHRINB_REV_PATHWAY | 29 | 6 | 15632 | 1249 |
Fgr,Map2k4,Lyn,Src,Rgs3,Hck |
| 2.482e-02 | -3.70 | MODULE_134 | MSigDB lists | MODULE_134 | 29 | 6 | 15632 | 1249 |
Fpr2,Fpr1,Ccr1,Cx3cr1,Ednrb,Ccl2 |
| 2.482e-02 | -3.70 | GO_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY | MSigDB lists | GO_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY | 29 | 6 | 15632 | 1249 |
H2-Q6,Il12b,H2-Q4,H2-Q7,Il12rb1,Ripk3 |
| 2.482e-02 | -3.70 | GO_NF_KAPPAB_BINDING | MSigDB lists | GO_NF_KAPPAB_BINDING | 29 | 6 | 15632 | 1249 |
Mtdh,Nfkbia,Psma6,Hdac1,Taf4b,Nfkbid |
| 2.482e-02 | -3.70 | chr4q32 | MSigDB lists | chr4q32 | 29 | 6 | 15632 | 1249 |
Ddx60,Mfap3l,Palld,Pdgfc,Rapgef2,Tlr2 |
| 2.482e-02 | -3.70 | GO_AXON_CYTOPLASM | MSigDB lists | GO_AXON_CYTOPLASM | 29 | 6 | 15632 | 1249 |
Uchl1,Rab21,Ap3m2,Hap1,Hif1a,Ap3b1 |
| 2.482e-02 | -3.70 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_UP | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_UP | 29 | 6 | 15632 | 1249 |
Flt1,Dse,Calcrl,Il2rg,Idi1,Ahr |
| 2.482e-02 | -3.70 | GO_DEMETHYLASE_ACTIVITY | MSigDB lists | GO_DEMETHYLASE_ACTIVITY | 29 | 6 | 15632 | 1249 |
Kdm4a,Kdm5b,Arid5b,Jmjd6,Jarid2,Kdm6b |
| 2.483e-02 | -3.70 | TTGTTT_FOXO4_01 | MSigDB lists | TTGTTT_FOXO4_01 | 1837 | 169 | 15632 | 1249 |
Kremen1,Irf4,Abcb1a,Stard5,Slc44a1,Znfx1,Dock4,Flt1,Slc7a11,Flrt3,Bcl2l11,Vcpip1,Angpt1,Rbms2,Pfkfb3,Prdx1,Rbm43,Pde3b,Gng11,Ppm1l,Egr1,Jag1,Bcl9,Zc3h7a,Akt3,Ptch1,P2ry2,Tagap,Igf1r,Acvr1b,Pik3cd,Tnfsf4,Dyrk2,Tmod3,Il13ra1,Ell2,Lztfl1,Acvr1,Nr3c1,Dennd1b,Dusp8,Egr2,Rhoq,Fchsd2,Itpr1,Dusp1,Ehd1,Clmp,Crim1,Clcn5,Cd83,Hif1a,Sertad3,Hlx,Hhex,Apba1,Lif,G3bp2,Dgka,Maff,Pdgfb,Btg2,Tlr1,Sipa1l1,4930523C07Rik,Arid4a,Slc4a7,Jarid2,Gch1,Map4k4,Sesn3,Tfec,Glrx,5430427O19Rik,Zhx2,Sec24b,Hcar2,Bambi,Pim1,Lox,S1pr2,Phlpp1,Mllt6,Dusp4,Tor1aip2,Gpr18,D16Ertd472e,Cited2,Ets2,Nr4a1,Klf3,Sqstm1,Klf7,Tle3,Pgm1,Gpr141,Arl4a,Evl,Palld,Bcor,Usp25,Stx6,Xaf1,Trim14,Cep350,Sik3,Lmo4,Dcun1d3,H3f3b,Abcc1,Rbms1,Ppp2r1b,Dnajb4,Trib1,Sema4c,Cpeb4,Dtx2,Pim2,Nfkbie,Ccng2,Hspa2,Sat1,Stat3,Itgb8,Rnf24,Arid5a,Serp1,Bcl6,Tcf4,Armcx6,Abcc5,Cd38,Rgs3,Etv5,Prpf38a,Gnb4,Pbx1,F11r,Cd74,Klf8,Ifih1,Prdm1,Slc25a12,Inhba,Ppp2r3a,Ext1,Sap30,Ddit4,Nrp2,Tmeff1,Rab10,Stxbp3,Lcp2,Pdgfrb,Fosb,Ttc9c,Dusp6,Rcl1,Gtpbp2,Pcdh7,Kitl,Inpp1,Phf6,Tmem229b,Frmd4a,Nr4a3,Il18,Rtn1,Pcgf5 |
| 2.483e-02 | -3.70 | GO_CELL_CYCLE_ARREST | MSigDB lists | GO_CELL_CYCLE_ARREST | 137 | 18 | 15632 | 1249 |
Notch2,Thbs1,Pnpt1,Cdkn1a,Cdkn2d,Pml,Plagl1,Kat2b,Prnp,Irf1,Il12b,Myc,Inhba,Atm,Eif4g2,Dusp1,Ppp1r15a,Map2k1 |
| 2.484e-02 | -3.70 | AACTGGA_MIR145 | MSigDB lists | AACTGGA_MIR145 | 207 | 25 | 15632 | 1249 |
Rin2,Rbpms,Arhgap26,Cited2,Mdfic,Plagl2,Rgs3,Slc25a25,Xrn1,Abr,Ccdc25,Vasn,Flnb,Map4k4,Rnf31,Dusp6,Dach1,Adam19,Actb,Plcl2,Lox,Acvr1b,Fndc3a,Herc6,Cpeb4 |
| 2.485e-02 | -3.70 | amide transport | biological process | GO:0042886 | 1281 | 105 | 20694 | 1406 |
Arf4,Hhex,Tap1,Isg15,Rtp4,Itgav,Rab32,Tbc1d13,Spire1,Parp11,Slc7a11,Lyn,Slc15a3,Rab9,Plek,Trem1,Grk3,Rrbp1,Kpna3,Il6,Ap3m2,Cox18,Ift22,Tbc1d1,Traf3ip2,Il1rn,Cd74,Arl5b,Dennd2a,Msr1,Stxbp3,Phip,Rabgef1,Rab10,Calcrl,Notch2,Serp1,Rab20,Rtn2,Arl5c,Ift57,Abcc1,Pml,Cdkn1a,Egr2,Stxbp1,Syk,Ric1,Snx2,Rffl,Apba1,Pou2f2,Tomm70a,Optn,Nlrp3,Notch1,Chmp4b,Ranbp2,Plekhf2,Nlrc4,Lcp2,Tlr6,Rab19,Slco3a1,Tlr2,Fam53c,Adar,Myo1b,Stat3,Aftph,Nxf1,Stx11,Rrs1,Sec24a,Snx10,Hap1,Rilpl1,Nos2,Rhbdf2,Arl4a,Dtx3l,Svbp,Vps54,Rnf19b,Rab3ip,Edn1,Stx6,Stau1,Tap2,Dennd1b,Nod2,Nfkbia,Arrdc4,D1Ertd622e,Rab21,Dio2,Kif5c,Abcb1a,Mcoln2,Ap3b1,Pdpn,Aim2,Ehd1,Rab11fip1,Fchsd2 |
| 2.494e-02 | -3.69 | MARTINEZ_RB1_TARGETS_UP | MSigDB lists | MARTINEZ_RB1_TARGETS_UP | 616 | 63 | 15632 | 1249 |
Trip13,Alas1,Zfp36,Atm,Rnf14,Tnfsf14,Fscn1,Actb,Clcf1,Rbms1,Pmepa1,Lrrc8c,Cdkn1a,Dram1,Itga9,Acsl1,Ier3,Ikzf1,Bnip3,Tgs1,Pcx,Cpd,Cx3cr1,Nr4a1,Klf3,Itgav,Rnf114,Pfkfb3,Gclc,Slc48a1,Tspo,Coa5,Ccnd2,Rtp4,H2-Aa,Wars,Car13,Junb,Gja1,Brd2,Hopx,Acsl5,Thbs1,Serpinb2,Tcea1,Hcar2,Glrx,Ptgs2,Il2rg,Mcm6,Nr3c1,Cp,Fgl2,Errfi1,Ccnd1,Lipe,Dusp1,Abcc5,Timp1,Serp1,Crim1,Cd74,Usp18 |
| 2.497e-02 | -3.69 | glutathione biosynthesis | BIOCYC pathways | MOUSE_GLUTATHIONESYN-PWY | 3 | 2 | 1025 | 97 |
Gclc,Gclm |
| 2.507e-02 | -3.69 | ossification | biological process | GO:0001503 | 219 | 23 | 20694 | 1406 |
H3f3b,Clec5a,Snx10,Asf1a,Bmp2,Sik3,Mmp13,Rsad2,Fzd1,Lox,Ptgs2,Ifitm1,Pdlim7,Acp5,Junb,Mmp14,Notch1,Fgr,Gja1,Ext1,Sbds,Adar,Csf1 |
| 2.508e-02 | -3.69 | RIZKI_TUMOR_INVASIVENESS_3D_DN | MSigDB lists | RIZKI_TUMOR_INVASIVENESS_3D_DN | 238 | 28 | 15632 | 1249 |
Sema3c,Slc31a2,Arid4a,Uba7,Tyk2,Jag1,Scn1b,Ksr1,Ube2l6,Il18,Pik3cd,Clec5a,Tlr3,Sp110,Ikbke,Oas3,Slc16a3,Casp1,Acvrl1,Dusp4,Abcb1a,Kat2b,Lrp8,Psme1,Bmp2,Rras2,Herc3,Cd83 |
| 2.514e-02 | -3.68 | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP | MSigDB lists | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP | 147 | 19 | 15632 | 1249 |
H2-Aa,Abcb1a,Wdr59,Mecp2,Psd4,Tor3a,Ptch1,Casp4,Rgs14,Tspan3,Ahsa1,Ciita,Pilrb2,Pilrb1,Rgs3,H2-Ab1,Lrch3,Adrb2,Il4ra |
| 2.514e-02 | -3.68 | GSE12003_4D_VS_8D_CULTURE_MIR223_KO_BM_PROGENITOR_DN | MSigDB lists | GSE12003_4D_VS_8D_CULTURE_MIR223_KO_BM_PROGENITOR_DN | 147 | 19 | 15632 | 1249 |
Tax1bp1,Pde3b,Osbpl3,Tmc3,Smox,Endod1,Cdk5r1,Phyh,Aida,Pdlim7,Trip13,Ddit4,Etv6,Cpd,Smpdl3b,Csrp1,Ttc9c,Ptch1,Arid5a |
| 2.521e-02 | -3.68 | Chondroitin sulfate/dermatan sulfate metabolism | REACTOME pathways | R-MMU-1793185 | 49 | 9 | 8608 | 757 |
Agrn,Sdc1,Sdc4,Vcan,Dse,Chst11,Gpc1,Ust,Sdc2 |
| 2.522e-02 | -3.68 | phosphatidylinositol 3-kinase complex, class I | cellular component | GO:0097651 | 4 | 2 | 20747 | 1409 |
Pik3r6,Pik3r5 |
| 2.522e-02 | -3.68 | microspike | cellular component | GO:0044393 | 4 | 2 | 20747 | 1409 |
Ezr,Fscn1 |
| 2.522e-02 | -3.68 | alphav-beta3 integrin-IGF-1-IGF1R complex | cellular component | GO:0035867 | 4 | 2 | 20747 | 1409 |
Itgav,Igf1r |
| 2.522e-02 | -3.68 | platelet dense granule | cellular component | GO:0042827 | 4 | 2 | 20747 | 1409 |
Abcc4,Itpr1 |
| 2.524e-02 | -3.68 | negative regulation of chemokine (C-C motif) ligand 5 production | biological process | GO:0071650 | 4 | 2 | 20694 | 1406 |
Arg2,Mul1 |
| 2.524e-02 | -3.68 | negative regulation of protein deubiquitination | biological process | GO:0090086 | 4 | 2 | 20694 | 1406 |
Trim21,Dnajb2 |
| 2.524e-02 | -3.68 | positive regulation of NK T cell proliferation | biological process | GO:0051142 | 4 | 2 | 20694 | 1406 |
Il12b,Il18 |
| 2.524e-02 | -3.68 | tripeptide transport | biological process | GO:0042939 | 4 | 2 | 20694 | 1406 |
Slc7a11,Abcc1 |
| 2.524e-02 | -3.68 | response to interleukin-13 | biological process | GO:0035962 | 4 | 2 | 20694 | 1406 |
Cd300lf,Il13ra1 |
| 2.524e-02 | -3.68 | glomerular mesangial cell differentiation | biological process | GO:0072008 | 4 | 2 | 20694 | 1406 |
Notch1,Pdgfb |
| 2.524e-02 | -3.68 | cell-cell adhesion mediated by integrin | biological process | GO:0033631 | 4 | 2 | 20694 | 1406 |
Itga5,Itga4 |
| 2.524e-02 | -3.68 | positive regulation of vitamin metabolic process | biological process | GO:0046136 | 4 | 2 | 20694 | 1406 |
Tnf,Il1b |
| 2.524e-02 | -3.68 | negative regulation of long-chain fatty acid import into cell | biological process | GO:0140213 | 4 | 2 | 20694 | 1406 |
Irs2,Thbs1 |
| 2.524e-02 | -3.68 | hypoxia-inducible factor-1alpha signaling pathway | biological process | GO:0097411 | 4 | 2 | 20694 | 1406 |
Hif1a,Pdk3 |
| 2.524e-02 | -3.68 | cochlear nucleus development | biological process | GO:0021747 | 4 | 2 | 20694 | 1406 |
Slc4a7,Sec24b |
| 2.524e-02 | -3.68 | regulation of interleukin-4 biosynthetic process | biological process | GO:0045402 | 4 | 2 | 20694 | 1406 |
Icosl,Irf4 |
| 2.524e-02 | -3.68 | sequestering of triglyceride | biological process | GO:0030730 | 4 | 2 | 20694 | 1406 |
Tnf,Il1b |
| 2.524e-02 | -3.68 | negative regulation of neutrophil apoptotic process | biological process | GO:0033030 | 4 | 2 | 20694 | 1406 |
Il18,Fcgr2b |
| 2.524e-02 | -3.68 | RNA 3' uridylation | biological process | GO:0071076 | 4 | 2 | 20694 | 1406 |
Tut7,Tent4a |
| 2.524e-02 | -3.68 | regulation of glutamate secretion, neurotransmission | biological process | GO:1903294 | 4 | 2 | 20694 | 1406 |
Kmo,Stxbp1 |
| 2.524e-02 | -3.68 | negative regulation of long-chain fatty acid import across plasma membrane | biological process | GO:0010748 | 4 | 2 | 20694 | 1406 |
Irs2,Thbs1 |
| 2.524e-02 | -3.68 | negative regulation of extracellular matrix constituent secretion | biological process | GO:0003332 | 4 | 2 | 20694 | 1406 |
Tnfrsf1b,Notch1 |
| 2.524e-02 | -3.68 | regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process | biological process | GO:0140192 | 4 | 2 | 20694 | 1406 |
Atp2b4,Pde4b |
| 2.524e-02 | -3.68 | negative regulation of adiponectin secretion | biological process | GO:0070164 | 4 | 2 | 20694 | 1406 |
Rab11fip1,Il1b |
| 2.524e-02 | -3.68 | cellular response to sodium arsenite | biological process | GO:1903936 | 4 | 2 | 20694 | 1406 |
Zc3h12a,Daxx |
| 2.524e-02 | -3.68 | positive regulation of isotype switching to IgE isotypes | biological process | GO:0048295 | 4 | 2 | 20694 | 1406 |
Tnfsf4,Clcf1 |
| 2.524e-02 | -3.68 | positive regulation of microglial cell migration | biological process | GO:1904141 | 4 | 2 | 20694 | 1406 |
Csf1,P2ry12 |
| 2.524e-02 | -3.68 | regulation of interleukin-6-mediated signaling pathway | biological process | GO:0070103 | 4 | 2 | 20694 | 1406 |
Ptpn2,Gfi1 |
| 2.524e-02 | -3.68 | transformation of host cell by virus | biological process | GO:0019087 | 4 | 2 | 20694 | 1406 |
Myc,Mmp9 |
| 2.524e-02 | -3.68 | glomerular mesangial cell development | biological process | GO:0072144 | 4 | 2 | 20694 | 1406 |
Pdgfb,Notch1 |
| 2.524e-02 | -3.68 | positive regulation of DNA methylation | biological process | GO:1905643 | 4 | 2 | 20694 | 1406 |
Myc,Mecp2 |
| 2.524e-02 | -3.68 | negative regulation of mast cell apoptotic process | biological process | GO:0033026 | 4 | 2 | 20694 | 1406 |
Stat5a,Kitl |
| 2.524e-02 | -3.68 | positive regulation of glutamate secretion, neurotransmission | biological process | GO:1903296 | 4 | 2 | 20694 | 1406 |
Kmo,Stxbp1 |
| 2.524e-02 | -3.68 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway | biological process | GO:2000587 | 4 | 2 | 20694 | 1406 |
Ptpn2,Glrx |
| 2.524e-02 | -3.68 | positive regulation of anion channel activity | biological process | GO:1901529 | 4 | 2 | 20694 | 1406 |
Abcb1a,Ptafr |
| 2.524e-02 | -3.68 | regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis | biological process | GO:2001270 | 4 | 2 | 20694 | 1406 |
Rffl,Rnf34 |
| 2.524e-02 | -3.68 | L-serine biosynthetic process | biological process | GO:0006564 | 4 | 2 | 20694 | 1406 |
Phgdh,Psat1 |
| 2.524e-02 | -3.68 | endothelin receptor signaling pathway | biological process | GO:0086100 | 4 | 2 | 20694 | 1406 |
Crkl,Ednrb |
| 2.524e-02 | -3.68 | cellular response to interleukin-13 | biological process | GO:0035963 | 4 | 2 | 20694 | 1406 |
Il13ra1,Cd300lf |
| 2.524e-02 | -3.68 | dynamin family protein polymerization involved in mitochondrial fission | biological process | GO:0003374 | 4 | 2 | 20694 | 1406 |
Mx2,Mx1 |
| 2.524e-02 | -3.68 | polyamine catabolic process | biological process | GO:0006598 | 4 | 2 | 20694 | 1406 |
Smox,Sat1 |
| 2.524e-02 | -3.68 | axon target recognition | biological process | GO:0007412 | 4 | 2 | 20694 | 1406 |
Stxbp1,Uchl1 |
| 2.524e-02 | -3.68 | negative regulation of interleukin-1-mediated signaling pathway | biological process | GO:2000660 | 4 | 2 | 20694 | 1406 |
Il6,Il1rn |
| 2.524e-02 | -3.68 | positive regulation of interferon-alpha biosynthetic process | biological process | GO:0045356 | 4 | 2 | 20694 | 1406 |
Tlr9,Tlr3 |
| 2.524e-02 | -3.68 | long-chain fatty-acyl-CoA biosynthetic process | biological process | GO:0035338 | 4 | 2 | 20694 | 1406 |
Acsl1,Acsl5 |
| 2.524e-02 | -3.68 | regulation of lung blood pressure | biological process | GO:0014916 | 4 | 2 | 20694 | 1406 |
Gch1,Nampt |
| 2.524e-02 | -3.68 | negative regulation of dendritic cell differentiation | biological process | GO:2001199 | 4 | 2 | 20694 | 1406 |
Tmem176b,Tmem176a |
| 2.524e-02 | -3.68 | regulation of metanephric mesenchymal cell migration | biological process | GO:2000589 | 4 | 2 | 20694 | 1406 |
Pdgfrb,Pdgfb |
| 2.524e-02 | -3.68 | MHC protein complex assembly | biological process | GO:0002396 | 4 | 2 | 20694 | 1406 |
Tapbp,Tapbpl |
| 2.524e-02 | -3.68 | re-entry into mitotic cell cycle | biological process | GO:0000320 | 4 | 2 | 20694 | 1406 |
Ccnd1,Myc |
| 2.524e-02 | -3.68 | vein smooth muscle contraction | biological process | GO:0014826 | 4 | 2 | 20694 | 1406 |
Ednrb,Edn1 |
| 2.524e-02 | -3.68 | glutathione transport | biological process | GO:0034635 | 4 | 2 | 20694 | 1406 |
Abcc1,Slc7a11 |
| 2.524e-02 | -3.68 | positive regulation of complement activation | biological process | GO:0045917 | 4 | 2 | 20694 | 1406 |
C3,Il1b |
| 2.524e-02 | -3.68 | positive regulation of glomerular filtration | biological process | GO:0003104 | 4 | 2 | 20694 | 1406 |
Pdgfb,Gja1 |
| 2.524e-02 | -3.68 | platelet activating factor metabolic process | biological process | GO:0046469 | 4 | 2 | 20694 | 1406 |
Pla2g7,Lpcat2 |
| 2.524e-02 | -3.68 | regulation of smooth muscle cell-matrix adhesion | biological process | GO:2000097 | 4 | 2 | 20694 | 1406 |
Serpine1,Plau |
| 2.524e-02 | -3.68 | positive regulation of extracellular exosome assembly | biological process | GO:1903553 | 4 | 2 | 20694 | 1406 |
Sdc4,Sdc1 |
| 2.524e-02 | -3.68 | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway | biological process | GO:0071878 | 4 | 2 | 20694 | 1406 |
Pde4b,Atp2b4 |
| 2.524e-02 | -3.68 | dynamin family protein polymerization involved in membrane fission | biological process | GO:0003373 | 4 | 2 | 20694 | 1406 |
Mx2,Mx1 |
| 2.524e-02 | -3.68 | Ras-like_GEF | interpro domains | IPR008937 | 24 | 5 | 19984 | 1430 |
Rapgef2,Rgl1,Rasgrp1,Rapgef5,Ralgds |
| 2.525e-02 | -3.68 | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | MSigDB lists | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | 187 | 23 | 15632 | 1249 |
Trim12c,Crlf3,Fbrsl1,Pbx1,Mtus1,Birc2,Dpy19l1,Ikzf1,Igsf6,Il18,Dyrk2,Epsti1,Igf1r,Vcam1,Adam19,Gcnt2,Samsn1,Hdc,Card6,Ube2e2,Usp12,Icosl,Med13 |
| 2.525e-02 | -3.68 | GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_UP | MSigDB lists | GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_UP | 187 | 23 | 15632 | 1249 |
Idi1,Serpinb2,Smox,Tmem176a,St3gal5,Ddit4,Klf2,Gdf15,Clec4n,Plek,Sla,Il15,Nlrp3,Sertad3,Tpx2,Tmem176b,Dusp4,Ifrd1,Vcan,Fut8,Spry2,Stat3,Ccr3 |
| 2.525e-02 | -3.68 | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN | MSigDB lists | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN | 187 | 23 | 15632 | 1249 |
Cutc,Ciita,Ccl22,Phactr4,Fgl2,Ccl2,Fut8,Casp1,Dusp1,Lrp11,Cmklr1,Osbpl3,Pdzd11,Il18,Ell2,Ptprj,Rap1gap2,Ccdc25,Sap30,Plekha2,Casp4,Ccl5,Ccr1 |
| 2.525e-02 | -3.68 | GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_DN | MSigDB lists | GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_DN | 187 | 23 | 15632 | 1249 |
Tlr1,Rap1gap2,Hk2,Stat4,Sh3bp4,Snx10,Rims3,Samsn1,Tnfaip2,Clic4,Abcc4,Igf2bp2,Igf1r,Traf3ip2,Tnfsf4,Casp1,Plac8,Oas3,Fos,Gclc,Rras2,Mdfic,Sell |
| 2.525e-02 | -3.68 | GO_MONOSACCHARIDE_METABOLIC_PROCESS | MSigDB lists | GO_MONOSACCHARIDE_METABOLIC_PROCESS | 187 | 23 | 15632 | 1249 |
Eno1,Serp1,Slc2a1,Tnf,Pcx,Fut8,Irs2,Pgm1,Tpi1,Atf3,Hk3,Gclc,Pfkfb3,Hk1,Eno2,Pdk3,Hk2,Oas1a,Slc25a12,Gpd2,Oas1g,Pgk1,Pfkl |
| 2.527e-02 | -3.68 | WANG_LSD1_TARGETS_DN | MSigDB lists | WANG_LSD1_TARGETS_DN | 37 | 7 | 15632 | 1249 |
Egr2,Stxbp1,Egr1,Cish,Junb,Rims3,Fos |
| 2.527e-02 | -3.68 | ALONSO_METASTASIS_EMT_UP | MSigDB lists | ALONSO_METASTASIS_EMT_UP | 37 | 7 | 15632 | 1249 |
Vcan,Fzd1,Cx3cr1,Ednrb,Tuba4a,Clic4,Itgav |
| 2.527e-02 | -3.68 | NAKAYAMA_FRA2_TARGETS | MSigDB lists | NAKAYAMA_FRA2_TARGETS | 37 | 7 | 15632 | 1249 |
Slc30a1,Bcl6,Gpr18,Sqstm1,Dusp4,Tagap,Mdm2 |
| 2.527e-02 | -3.68 | GO_RESPONSE_TO_PH | MSigDB lists | GO_RESPONSE_TO_PH | 37 | 7 | 15632 | 1249 |
Gja1,Nox1,Src,Clcn7,Slc9a1,Gpr68,Hvcn1 |
| 2.527e-02 | -3.68 | GENTILE_UV_RESPONSE_CLUSTER_D8 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D8 | 37 | 7 | 15632 | 1249 |
Cdyl,Hivep2,Jun,Tab2,Ldlr,Rbms1,Met |
| 2.527e-02 | -3.68 | ZUCCHI_METASTASIS_DN | MSigDB lists | ZUCCHI_METASTASIS_DN | 37 | 7 | 15632 | 1249 |
Zyx,Gadd45b,Nfkbia,Lif,Cxcl2,Cxcl1,Sat1 |
| 2.532e-02 | -3.68 | GSE3720_UNSTIM_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_UP | MSigDB lists | GSE3720_UNSTIM_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_UP | 157 | 20 | 15632 | 1249 |
Psmb8,Gsdmd,Psma6,Tnfsf8,Nfkbib,Myc,Psme2,Procr,Ddit4,Tapbpl,Rcsd1,Ddx58,Nkiras1,Odc1,Traf3ip2,Psmb6,Larp1,Chmp4b,Ikbke,Extl2 |
| 2.532e-02 | -3.68 | GSE9601_UNTREATED_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP | MSigDB lists | GSE9601_UNTREATED_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP | 157 | 20 | 15632 | 1249 |
Nfkbie,Csf1,Pdgfb,Rgs14,Csrp1,Ezr,Samhd1,Relb,Epsti1,Chmp4b,Gbp2b,Tnip1,Gbp3,Traf1,Psmb10,Tpx2,Pim1,Irf1,Phyh,Mxd1 |
| 2.532e-02 | -3.68 | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP | MSigDB lists | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP | 157 | 20 | 15632 | 1249 |
H2-Ab1,Lrch3,Apba1,Mppe1,Plau,Orai2,Tnfaip2,Tnfrsf8,Clcn5,Hck,Abcc5,Pid1,Irf8,Ksr1,Inpp5b,Caml,Ctsc,Arhgap26,Nod2,Phactr4 |
| 2.534e-02 | -3.68 | organelle transport along microtubule | biological process | GO:0072384 | 73 | 10 | 20694 | 1406 |
Ap3m2,Kif3c,Hif1a,Dync1h1,Hap1,Uchl1,Syne2,Map2k1,Ap3b1,Rasgrp1 |
| 2.535e-02 | -3.68 | mouse chr6|6 A2 | chromosome location | mouse chr6|6 A2 | 11 | 3 | 24173 | 1464 |
St7,Tfec,Cav1 |
| 2.536e-02 | -3.67 | GSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP | MSigDB lists | GSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP | 177 | 22 | 15632 | 1249 |
Rgl1,Rabgef1,Osm,Tnfsf14,Il10,Csf3,Dtx2,Cpeb4,Tlr3,Slamf8,Gcnt2,Ralgds,Rgs1,Tiparp,B4galt4,Ccl2,Dusp4,Mdm2,Optn,Mafk,Csrnp1,Sphk1 |
| 2.536e-02 | -3.67 | GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN | 177 | 22 | 15632 | 1249 |
Sesn3,Cnp,Arid5a,Klf2,Tor1aip2,Inpp5b,Stard5,Ccdc86,Tlr1,Mmd,Rnf19a,Psma6,St3gal1,Dck,Egr1,Cox18,Pttg1,Mul1,Slco3a1,Ifih1,Slc25a22,Nr4a3 |
| 2.536e-02 | -3.67 | GSE3982_NEUTROPHIL_VS_TH2_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH2_DN | 177 | 22 | 15632 | 1249 |
Birc3,Cdyl,Usp12,Mmd,Ep400,Rcn1,Odc1,Rcan1,Cd200,Kif5c,Tcea1,Rcl1,Osbpl3,Rbbp8,Dpy19l1,Atp13a1,Myc,Pla2g4a,Pttg1,Rars,Tsku,Bfar |
| 2.536e-02 | -3.67 | GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_DN | 177 | 22 | 15632 | 1249 |
Tsku,Plaur,Gclc,Prdx1,Map3k8,Slco3a1,Sema4a,Kif3c,Adora2b,Kcna3,Denr,Mtdh,Jag1,Btg2,Lmo4,Itgal,Myo1b,Spryd7,Ctu1,Myadm,Cx3cr1,Aoah |
| 2.536e-02 | -3.67 | YYCATTCAWW_UNKNOWN | MSigDB lists | YYCATTCAWW_UNKNOWN | 177 | 22 | 15632 | 1249 |
Gclc,Etv5,Rgs3,Ube2e1,Atf3,Lrp8,Lif,Vcan,Ccnd1,Dusp4,Ets2,Dio2,Igf1r,Prkar2b,Ppa1,Nr4a3,Inhba,Maff,Pde4b,P4ha1,Daam1,Fosb |
| 2.536e-02 | -3.67 | GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_DN | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_DN | 177 | 22 | 15632 | 1249 |
Pou2f2,Oas2,Kctd12,Usp12,Psd,Stat4,Ppp2r5a,Trip10,Ppp1r15a,Brd2,Slc31a2,Esd,Lhx2,Pfkl,Cd14,Rsbn1,Cmklr1,Myd88,Il2rg,Gpd2,Fgr,Sdc1 |
| 2.536e-02 | -3.67 | GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_DN | MSigDB lists | GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_DN | 177 | 22 | 15632 | 1249 |
Ifi204,Plagl1,Ifi214,Nsmaf,Ptk2,Stat1,Rnf139,Vegfc,Ifi207,Ap3m2,Snapc1,Mtus1,Cacybp,Ifi209,Mndal,Ifi205,Ascc3,Ifi213,Ifi203,Ifi211,Ifi208,Slc39a4 |
| 2.538e-02 | -3.67 | acidic amino acid transport | biological process | GO:0015800 | 34 | 6 | 20694 | 1406 |
Slc25a22,Slc7a11,Slc25a12,Slc13a3,Lrrc8c,Apba1 |
| 2.538e-02 | -3.67 | phosphatidylinositol 3-kinase signaling | biological process | GO:0014065 | 34 | 6 | 20694 | 1406 |
Htr2b,Edn1,Pik3r6,Htr2a,Pik3r5,Pik3cd |
| 2.538e-02 | -3.67 | superoxide metabolic process | biological process | GO:0006801 | 34 | 6 | 20694 | 1406 |
Nos2,Sod2,Edn1,Nqo1,Nox1,Prdx1 |
| 2.538e-02 | -3.67 | serine family amino acid metabolic process | biological process | GO:0009069 | 34 | 6 | 20694 | 1406 |
Tha1,Psat1,Phgdh,Gclc,Txnrd1,Gclm |
| 2.539e-02 | -3.67 | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP | MSigDB lists | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP | 167 | 21 | 15632 | 1249 |
Rrs1,Eno1,Cenpe,Bcl2l11,Vcan,Srxn1,Ggct,Mmp14,Phlda1,Odc1,Mcm6,Dck,Gda,Plaur,Cd164,Vegfc,Lrrc8c,Rbl1,Pgk1,Crlf3,Serpinb2 |
| 2.539e-02 | -3.67 | GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | MSigDB lists | GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | 167 | 21 | 15632 | 1249 |
Plekhf2,Slc7a11,Fosb,Dock4,Gem,Rasgrp1,Usp12,Zfp324,Cnot4,Mecp2,Mmp9,Dck,Smox,Magohb,Asb13,Frmd4a,Ms4a6d,Htr2a,Olr1,Mcmbp,Plagl2 |
| 2.539e-02 | -3.67 | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_2H_DN | MSigDB lists | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_2H_DN | 167 | 21 | 15632 | 1249 |
Ifit1bl1,Gsdmd,Ifit1bl2,Dusp1,Psmd10,Eno1,Casp4,Pnp2,Cd69,Cd55,Aim2,Bcor,Trim13,Usp18,Pgm1,Arl4a,Cxcl10,Mcm6,Sav1,Il15,Asf1a |
| 2.539e-02 | -3.67 | CYCLIN_D1_UP.V1_UP | MSigDB lists | CYCLIN_D1_UP.V1_UP | 167 | 21 | 15632 | 1249 |
Smox,Plk3,Egr1,Traf1,Col4a2,Batf,Hk3,Tap1,Stat5a,Tagln,Fzd5,Dmwd,Zyx,Hspa1a,Ets2,Ksr1,Bcl9,Casp3,Pde1b,Cox17,Cebpd |
| 2.539e-02 | -3.67 | GSE22611_UNSTIM_VS_6H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP | MSigDB lists | GSE22611_UNSTIM_VS_6H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP | 167 | 21 | 15632 | 1249 |
Slamf7,Extl2,Klf7,Lrp8,Abr,Xkr8,Ebi3,Kat2b,Tgfbi,Prnp,Mmp14,Bcorl1,Slc25a12,Ogfrl1,Tlk2,Taf4b,Hk1,Tor3a,Tmem184b,Dmwd,Itpr1 |
| 2.542e-02 | -3.67 | tight junction | cellular component | GO:0070160 | 127 | 15 | 20747 | 1409 |
Ddx58,Rapgef2,Usp53,Ccnd1,Cyth3,Mtdh,Micall2,Rap2c,Rpgrip1l,Fzd5,Frmd4a,F11r,Vasp,Clmp,Mpp7 |
| 2.548e-02 | -3.67 | GSE13887_RESTING_VS_ACT_CD4_TCELL_DN | MSigDB lists | GSE13887_RESTING_VS_ACT_CD4_TCELL_DN | 118 | 16 | 15632 | 1249 |
Ikbkg,Irf7,Ets2,Itgal,Itgb8,Nat2,Il18rap,Casp2,Nod2,Parp3,Hmgcs1,Idi1,Bmp2,Hinfp,Irak3,Glrx |
| 2.566e-02 | -3.66 | regulation of DNA repair | biological process | GO:0006282 | 116 | 14 | 20694 | 1406 |
Fignl2,Dek,Spire1,Parp9,Radx,Ier3,Sirt1,Timeless,Dtx3l,Eya4,Cgas,Parp3,Ppp4r2,Pml |
| 2.572e-02 | -3.66 | positive regulation of dephosphorylation | biological process | GO:0035306 | 53 | 8 | 20694 | 1406 |
Pdgfrb,Ppp1r15a,Jak2,Plek,Ppp1r15b,Bmp2,Ripk3,Ppp2r5a |
| 2.572e-02 | -3.66 | negative regulation of gliogenesis | biological process | GO:0014014 | 53 | 8 | 20694 | 1406 |
Tspo,Ldlr,Notch1,Fas,Hmga2,Mecp2,Kdm4a,Stap1 |
| 2.572e-02 | -3.66 | zymogen activation | biological process | GO:0031638 | 53 | 8 | 20694 | 1406 |
Plau,Plat,C1rl,Mmp14,Casp8,Ripk2,Pgk1,C1ra |
| 2.572e-02 | -3.66 | mammary gland morphogenesis | biological process | GO:0060443 | 53 | 8 | 20694 | 1406 |
Kdm5b,Csf1,Cav1,Stat5a,Pml,Ptch1,Src,Nr3c1 |
| 2.579e-02 | -3.66 | MULLIGHAN_MLL_SIGNATURE_2_UP | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_2_UP | 376 | 41 | 15632 | 1249 |
Mppe1,Adrb2,Ptafr,Rnf19b,Slc31a1,Plaur,5430427O19Rik,Il1rn,Clcn7,Tnfaip2,Hcls1,Tor1aip1,Itgal,C1rl,Atp6v1d,Dach1,Ccr1,Psmb8,Snx10,Lnpep,Psd4,Tdrd7,Reps1,Nlrp3,Malt1,Abr,Prrg4,Mapkapk2,Hck,Pilra,Batf,Sla,Rgs14,Arhgef3,Cd302,Eno1,Syk,Casp1,Slc16a3,Pla2g4a,Ikzf1 |
| 2.593e-02 | -3.65 | GO_PEPTIDYL_AMINO_ACID_MODIFICATION | MSigDB lists | GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 763 | 76 | 15632 | 1249 |
Prkx,Ripk2,Smc5,Naa25,St3gal1,Prdm9,Pdgfb,Tyk2,Il12rb1,Arid4a,Cdyl,Ttc9c,Osm,Pdgfrb,Map2k1,Plk2,Sgk3,Hck,Pml,Lif,Jmjd6,Fgr,St3gal6,Ifih1,Setdb2,Egr2,Fut8,Acvr1,Mecp2,Mdm2,Tlk2,P4ha2,Dpy19l1,Axl,Src,Stat5a,Tpst1,Kdr,Dr1,Jak2,Vrk2,Igf1r,Dyrk2,Ptk2,Lyn,Map2k4,Acvr1b,Ep400,St3gal5,Akt3,Egln3,Met,Hat1,Sirt1,Rictor,P4ha1,Atm,Pdk3,S100a8,Nos2,F10,Il15,Mark2,Nek6,Mapkapk2,St3gal3,Cdk5r1,Mul1,Kat2b,Prkce,Irf4,Syk,Eif2ak2,Flt1,Morc3,Tet2 |
| 2.597e-02 | -3.65 | GO_SECRETION_BY_CELL | MSigDB lists | GO_SECRETION_BY_CELL | 452 | 48 | 15632 | 1249 |
Axl,Timp1,Rab11fip1,Pnp2,Mecp2,Apba1,Aim2,Hck,Notch1,Tuba4a,Ccl5,Plek,Ccr1,Serpine1,Lcp2,Stxbp3,Pdgfb,Stx11,Hap1,Inhba,Traf3ip2,Nr4a3,Thbs1,Il1rn,Pcdh7,Pf4,Abcc4,Vegfc,Syk,Nlrc4,Il6,Edn1,Ppfia3,Nod2,Tlr6,Stxbp1,Nlrp3,Ltbp2,Nos2,Rims3,Pou2f2,Rasgrp1,Lyn,Pik3cd,Pdzd11,Tlr2,Tnfaip2,Trem1 |
| 2.608e-02 | -3.65 | GO_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | 128 | 17 | 15632 | 1249 |
Ccl12,Sod2,Axl,Jun,Gclm,Btg2,Mecp2,Stxbp1,Hmox1,Cpeb4,Nr4a3,Map2k4,Hif1a,Gclc,Clcf1,Jak2,Angpt1 |
| 2.608e-02 | -3.65 | CRX_NRL_DN.V1_UP | MSigDB lists | CRX_NRL_DN.V1_UP | 128 | 17 | 15632 | 1249 |
Tnfaip3,Slc25a25,Hcls1,Ier3,Arg2,St3gal1,Psd,Bst1,Sap30,Ext1,Ttc39c,Hspa1a,Plekha2,Gpsm2,Slc16a3,Bcl2l11,Ahrr |
| 2.608e-02 | -3.65 | GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_DN | MSigDB lists | GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_DN | 128 | 17 | 15632 | 1249 |
Ifna1,Cd83,Ccl4,Ifna2,Cd74,Tulp3,Odc1,Tpx2,Tnc,Trip13,Ifna6,Inhba,Ifna5,Cpd,Ccne1,Srm,Myo1b |
| 2.612e-02 | -3.65 | GO_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_CYTOSKELETON_ORGANIZATION | 752 | 75 | 15632 | 1249 |
Arhgap26,Rhoq,Micall2,Birc2,Bcl6,Gpsm2,Rgs14,Swap70,Src,Dync1h1,Tnf,Rnd1,F11r,Plk3,Vasp,Antxr1,Pdlim7,Vps54,Sipa1l1,Pdgfrb,Cnp,Daam1,Plk2,Myo1b,Brwd3,Plek,Fmnl2,Spire1,Triobp,Phactr4,Mid1,S1pr2,Ccl2,Katna1,Spry2,Rhof,Zyx,Trip10,Nlrc4,Sbds,Ccl12,Cnn2,Ezr,Slc16a1,Cdc42ep2,Rnd3,Sass6,Tpx2,Phip,Nek6,Palld,Nck1,Abr,Evl,Rhou,Syne2,Rnf19a,Rictor,Flnb,Cnn3,Pstpip2,Cenpj,Cep350,Cav1,Birc3,Wdr43,Hcls1,Jak2,Fscn1,Cflar,Whamm,Tmod3,Rac3,Fignl2,Ptk2 |
| 2.614e-02 | -3.64 | tetraspanin-enriched microdomain | cellular component | GO:0097197 | 10 | 3 | 20747 | 1409 |
Samhd1,Scimp,Pdpn |
| 2.614e-02 | -3.64 | intercellular canaliculus | cellular component | GO:0046581 | 10 | 3 | 20747 | 1409 |
Mmp13,Mtdh,Abcb1a |
| 2.615e-02 | -3.64 | OUILLETTE_CLL_13Q14_DELETION_DN | MSigDB lists | OUILLETTE_CLL_13Q14_DELETION_DN | 54 | 9 | 15632 | 1249 |
Cish,Etv5,Phlpp1,Parp9,Eno2,Dusp6,Trim13,Aldh1b1,Cdk5r1 |
| 2.615e-02 | -3.64 | MODULE_237 | MSigDB lists | MODULE_237 | 54 | 9 | 15632 | 1249 |
Sell,Heatr6,Kcna3,Pttg1,Klf8,Itgav,Atm,Asf1a,Tifa |
| 2.615e-02 | -3.64 | GO_ER_TO_GOLGI_TRANSPORT_VESICLE_MEMBRANE | MSigDB lists | GO_ER_TO_GOLGI_TRANSPORT_VESICLE_MEMBRANE | 54 | 9 | 15632 | 1249 |
H2-Aa,Sec24a,Sec24b,H2-Q4,H2-Eb1,H2-Ab1,H2-Q7,Cd74,H2-Q6 |
| 2.617e-02 | -3.64 | MHC class Ib protein binding | molecular function | GO:0023029 | 4 | 2 | 20217 | 1400 |
Tap2,Tap1 |
| 2.617e-02 | -3.64 | NAD+ nucleosidase activity | molecular function | GO:0003953 | 4 | 2 | 20217 | 1400 |
Cd38,Bst1 |
| 2.617e-02 | -3.64 | diamine N-acetyltransferase activity | molecular function | GO:0004145 | 4 | 2 | 20217 | 1400 |
Kat2b,Sat1 |
| 2.617e-02 | -3.64 | collagen V binding | molecular function | GO:0070052 | 4 | 2 | 20217 | 1400 |
Thbs1,Gpc1 |
| 2.617e-02 | -3.64 | very-low-density lipoprotein particle receptor activity | molecular function | GO:0030229 | 4 | 2 | 20217 | 1400 |
Lrp8,Ldlr |
| 2.617e-02 | -3.64 | NF-kappaB-inducing kinase activity | molecular function | GO:0004704 | 4 | 2 | 20217 | 1400 |
Ikbke,Ripk3 |
| 2.617e-02 | -3.64 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity | molecular function | GO:0003836 | 4 | 2 | 20217 | 1400 |
St3gal1,St3gal3 |
| 2.617e-02 | -3.64 | scavenger receptor binding | molecular function | GO:0005124 | 4 | 2 | 20217 | 1400 |
Fpr2,Fpr1 |
| 2.617e-02 | -3.64 | protein tyrosine/threonine phosphatase activity | molecular function | GO:0008330 | 4 | 2 | 20217 | 1400 |
Dusp4,Dusp1 |
| 2.617e-02 | -3.64 | methylenetetrahydrofolate dehydrogenase (NADP+) activity | molecular function | GO:0004488 | 4 | 2 | 20217 | 1400 |
Mthfd2,Mthfd1l |
| 2.617e-02 | -3.64 | cellular response to lipoteichoic acid | biological process | GO:0071223 | 10 | 3 | 20694 | 1406 |
Ripk2,Tlr2,Cd14 |
| 2.617e-02 | -3.64 | positive regulation of granulocyte differentiation | biological process | GO:0030854 | 10 | 3 | 20694 | 1406 |
Ikzf1,Hcls1,Trib1 |
| 2.617e-02 | -3.64 | CD8-positive, alpha-beta T cell differentiation | biological process | GO:0043374 | 10 | 3 | 20694 | 1406 |
Gpr18,Tnfsf8,Irf1 |
| 2.617e-02 | -3.64 | positive regulation of integrin activation | biological process | GO:0033625 | 10 | 3 | 20694 | 1406 |
Plek,Piezo1,P2ry12 |
| 2.617e-02 | -3.64 | response to lipoteichoic acid | biological process | GO:0070391 | 10 | 3 | 20694 | 1406 |
Ripk2,Tlr2,Cd14 |
| 2.617e-02 | -3.64 | negative regulation of endothelial cell differentiation | biological process | GO:0045602 | 10 | 3 | 20694 | 1406 |
Acvrl1,Zeb1,Jag1 |
| 2.617e-02 | -3.64 | positive regulation of hepatocyte proliferation | biological process | GO:2000347 | 10 | 3 | 20694 | 1406 |
Itpr1,Tnfaip3,Cflar |
| 2.617e-02 | -3.64 | regulation of autophagosome maturation | biological process | GO:1901096 | 10 | 3 | 20694 | 1406 |
Irgm1,Adrb2,Irgm2 |
| 2.617e-02 | -3.64 | regulation of NK T cell activation | biological process | GO:0051133 | 10 | 3 | 20694 | 1406 |
Il18,Il12b,Hsph1 |
| 2.617e-02 | -3.64 | acute inflammatory response to antigenic stimulus | biological process | GO:0002438 | 10 | 3 | 20694 | 1406 |
Fcgr1,Icam1,Serpinb9 |
| 2.617e-02 | -3.64 | negative regulation of macrophage migration | biological process | GO:1905522 | 10 | 3 | 20694 | 1406 |
Slamf8,Cd200,Stap1 |
| 2.617e-02 | -3.64 | regulation of neutrophil activation | biological process | GO:1902563 | 10 | 3 | 20694 | 1406 |
Abr,Syk,Ptafr |
| 2.617e-02 | -3.64 | deadenylation-dependent decapping of nuclear-transcribed mRNA | biological process | GO:0000290 | 10 | 3 | 20694 | 1406 |
Dcp2,Noct,Dcp1a |
| 2.617e-02 | -3.64 | positive regulation of extracellular matrix disassembly | biological process | GO:0090091 | 10 | 3 | 20694 | 1406 |
Pdpn,Il6,Fscn1 |
| 2.617e-02 | -3.64 | positive regulation of toll-like receptor 4 signaling pathway | biological process | GO:0034145 | 10 | 3 | 20694 | 1406 |
Peli1,Nr1h3,Wdfy1 |
| 2.617e-02 | -3.64 | negative regulation of nitric-oxide synthase activity | biological process | GO:0051001 | 10 | 3 | 20694 | 1406 |
Arg2,Atp2b4,Cav1 |
| 2.617e-02 | -3.64 | sphingosine-1-phosphate receptor signaling pathway | biological process | GO:0003376 | 10 | 3 | 20694 | 1406 |
Sphk1,Ezr,S1pr2 |
| 2.617e-02 | -3.64 | marginal zone B cell differentiation | biological process | GO:0002315 | 10 | 3 | 20694 | 1406 |
Tnfaip3,Notch2,Dock10 |
| 2.617e-02 | -3.64 | regulation of growth rate | biological process | GO:0040009 | 10 | 3 | 20694 | 1406 |
Notch2,Notch1,Ahr |
| 2.617e-02 | -3.64 | leukocyte aggregation | biological process | GO:0070486 | 10 | 3 | 20694 | 1406 |
Il1b,S100a8,Spn |
| 2.617e-02 | -3.64 | Rap protein signal transduction | biological process | GO:0032486 | 10 | 3 | 20694 | 1406 |
Rap2c,Rapgef2,Plk2 |
| 2.617e-02 | -3.64 | regulation of macrophage apoptotic process | biological process | GO:2000109 | 10 | 3 | 20694 | 1406 |
Sirt1,Ccl5,Nod2 |
| 2.617e-02 | -3.64 | positive regulation of mucus secretion | biological process | GO:0070257 | 10 | 3 | 20694 | 1406 |
Prkce,P2ry2,Ptger4 |
| 2.617e-02 | -3.64 | regulation of interleukin-10 secretion | biological process | GO:2001179 | 10 | 3 | 20694 | 1406 |
Cd274,Ptger4,Lgals9 |
| 2.628e-02 | -3.64 | ARID4B (AT-rich interaction domain 4B) | protein interactions | 51742 | 3 | 2 | 7778 | 753 |
Max,Sinhcaf |
| 2.628e-02 | -3.64 | Relb (avian reticuloendotheliosis viral (v-rel) oncogene related B) | protein interactions | 19698 | 3 | 2 | 7778 | 753 |
Nfkb1,Nfkb2 |
| 2.628e-02 | -3.64 | Msx2 (msh homeobox 2) | protein interactions | 17702 | 3 | 2 | 7778 | 753 |
Spen,Hdac1 |
| 2.628e-02 | -3.64 | Gzmb (granzyme B) | protein interactions | 14939 | 3 | 2 | 7778 | 753 |
Casp3,Casp7 |
| 2.628e-02 | -3.64 | DYNLT3 (dynein light chain Tctex-type 3) | protein interactions | 6990 | 3 | 2 | 7778 | 753 |
Dync1i2,Dync1h1 |
| 2.628e-02 | -3.64 | TUBB6 (tubulin beta 6 class V) | protein interactions | 84617 | 3 | 2 | 7778 | 753 |
Ksr1,Ppp6r1 |
| 2.628e-02 | -3.64 | Rassf1 (Ras association (RalGDS/AF-6) domain family member 1) | protein interactions | 56289 | 3 | 2 | 7778 | 753 |
Daxx,Mdm2 |
| 2.628e-02 | -3.64 | FOXK1 (forkhead box K1) | protein interactions | 221937 | 3 | 2 | 7778 | 753 |
Max,Sinhcaf |
| 2.628e-02 | -3.64 | CNOT2 (CCR4-NOT transcription complex subunit 2) | protein interactions | 4848 | 3 | 2 | 7778 | 753 |
Tnks1bp1,Rrbp1 |
| 2.628e-02 | -3.64 | SAP130 (Sin3A associated protein 130) | protein interactions | 79595 | 3 | 2 | 7778 | 753 |
Sinhcaf,Max |
| 2.628e-02 | -3.64 | Ccr1 (chemokine (C-C motif) receptor 1) | protein interactions | 12768 | 3 | 2 | 7778 | 753 |
Ccl3,Ccl5 |
| 2.628e-02 | -3.64 | CRTC3 (CREB regulated transcription coactivator 3) | protein interactions | 64784 | 3 | 2 | 7778 | 753 |
Stat3,Chmp4b |
| 2.628e-02 | -3.64 | Ifih1 (interferon induced with helicase C domain 1) | protein interactions | 71586 | 3 | 2 | 7778 | 753 |
Ddx60,Trim13 |
| 2.628e-02 | -3.64 | TRIM21 (tripartite motif containing 21) | protein interactions | 6737 | 3 | 2 | 7778 | 753 |
Mdm2,Junb |
| 2.628e-02 | -3.64 | Pag1 (phosphoprotein associated with glycosphingolipid microdomains 1) | protein interactions | 94212 | 3 | 2 | 7778 | 753 |
Socs1,Lyn |
| 2.628e-02 | -3.64 | Sh3bp2 (SH3-domain binding protein 2) | protein interactions | 24055 | 3 | 2 | 7778 | 753 |
Src,Syk |
| 2.628e-02 | -3.64 | Tmem115 (transmembrane protein 115) | protein interactions | 56395 | 3 | 2 | 7778 | 753 |
Tnf,Tab2 |
| 2.628e-02 | -3.64 | IRAK1 (interleukin 1 receptor associated kinase 1) | protein interactions | 3654 | 3 | 2 | 7778 | 753 |
Rsad2,Peli1 |
| 2.628e-02 | -3.64 | ING1 (inhibitor of growth family member 1) | protein interactions | 3621 | 3 | 2 | 7778 | 753 |
Max,Sinhcaf |
| 2.628e-02 | -3.64 | Pole (polymerase (DNA directed), epsilon) | protein interactions | 18973 | 3 | 2 | 7778 | 753 |
Timeless,Mdm2 |
| 2.628e-02 | -3.64 | DNAJC10 (DnaJ heat shock protein family (Hsp40) member C10) | protein interactions | 54431 | 3 | 2 | 7778 | 753 |
Ksr1,Cenpe |
| 2.628e-02 | -3.64 | KRBA2 (KRAB-A domain containing 2) | protein interactions | 124751 | 3 | 2 | 7778 | 753 |
Rrbp1,Brwd3 |
| 2.628e-02 | -3.64 | EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) | protein interactions | 5610 | 3 | 2 | 7778 | 753 |
Rrbp1,Jak2 |
| 2.628e-02 | -3.64 | XRCC1 (X-ray repair cross complementing 1) | protein interactions | 7515 | 3 | 2 | 7778 | 753 |
Junb,Tpx2 |
| 2.628e-02 | -3.64 | BRMS1 (BRMS1 transcriptional repressor and anoikis regulator) | protein interactions | 25855 | 3 | 2 | 7778 | 753 |
Max,Sinhcaf |
| 2.628e-02 | -3.64 | Sap30 (sin3 associated polypeptide) | protein interactions | 60406 | 3 | 2 | 7778 | 753 |
Ifrd1,Tet2 |
| 2.628e-02 | -3.64 | SDCBP (syndecan binding protein) | protein interactions | 6386 | 3 | 2 | 7778 | 753 |
Chmp4b,Junb |
| 2.628e-02 | -3.64 | HACD2 (3-hydroxyacyl-CoA dehydratase 2) | protein interactions | 201562 | 3 | 2 | 7778 | 753 |
Max,Tpx2 |
| 2.628e-02 | -3.64 | EDAR (ectodysplasin A receptor) | protein interactions | 10913 | 3 | 2 | 7778 | 753 |
Traf2,Traf1 |
| 2.628e-02 | -3.64 | DDX27 (DEAD-box helicase 27) | protein interactions | 55661 | 3 | 2 | 7778 | 753 |
Rrbp1,Ktn1 |
| 2.628e-02 | -3.64 | PRDX2 (peroxiredoxin 2) | protein interactions | 7001 | 3 | 2 | 7778 | 753 |
Tor1aip1,Prdx1 |
| 2.628e-02 | -3.64 | Bnc1 (basonuclin 1) | protein interactions | 12173 | 3 | 2 | 7778 | 753 |
Pmaip1,Bcl2l11 |
| 2.628e-02 | -3.64 | UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1) | protein interactions | 7386 | 3 | 2 | 7778 | 753 |
Peli1,Rmdn3 |
| 2.628e-02 | -3.64 | Nod2 (nucleotide-binding oligomerization domain containing 2) | protein interactions | 257632 | 3 | 2 | 7778 | 753 |
Socs3,Ripk2 |
| 2.628e-02 | -3.64 | RPL18 (ribosomal protein L18) | protein interactions | 6141 | 3 | 2 | 7778 | 753 |
Rrbp1,Brwd3 |
| 2.633e-02 | -3.64 | ARMS-mediated activation | REACTOME pathways | R-MMU-170984 | 218 | 28 | 8608 | 757 |
Irs2,Ppp2r5a,Src,Angpt1,Psme2b,Pdgfb,Spred1,Kitl,Jak2,Map2k1,Ppp2r1b,Pdgfrb,Ksr1,Il2rg,Psme2,Psma6,Psmd10,Met,Ptk2,Psmb8,Psmb10,Psmb6,Dusp6,Psme1,Dusp5,Rasgrp1,Psmb9,Rapgef2 |
| 2.634e-02 | -3.64 | low-density lipoprotein particle binding | molecular function | GO:0030169 | 17 | 4 | 20217 | 1400 |
Scarf1,Ldlr,Msr1,Thbs1 |
| 2.641e-02 | -3.63 | HS-GAG degradation | REACTOME pathways | R-MMU-2024096 | 20 | 5 | 8608 | 757 |
Gpc1,Sdc4,Sdc2,Agrn,Sdc1 |
| 2.646e-02 | -3.63 | MODULE_63 | MSigDB lists | MODULE_63 | 198 | 24 | 15632 | 1249 |
Olr1,Clcn5,Cd80,Fcgr1,Il4ra,Cd180,S1pr2,Itgb8,Kcnj2,Csf3r,Axl,Kdr,Adrb2,Il2rg,Fpr1,Itga9,Il13ra1,Pdgfrb,P2ry2,Itgal,Cd86,Gja1,Tnfrsf1b,Fcgr4 |
| 2.646e-02 | -3.63 | MODULE_105 | MSigDB lists | MODULE_105 | 198 | 24 | 15632 | 1249 |
Mmd,Cnn3,Tlr1,Asns,Lad1,Lmo4,Gja1,P4ha1,Stip1,Keap1,Idi1,Cacnb3,Cox17,Vcan,Birc2,Mgat1,Cited2,Hsph1,Rgs3,Ahr,Col4a2,Gbe1,Atf3,Col18a1 |
| 2.650e-02 | -3.63 | positive regulation of viral process | biological process | GO:0048524 | 84 | 11 | 20694 | 1406 |
Trim30a,Adar,Mdfic,Jun,Pcx,Trim21,Stau1,Larp1,Chmp4b,Notch1,Cd74 |
| 2.650e-02 | -3.63 | cholesterol homeostasis | biological process | GO:0042632 | 84 | 11 | 20694 | 1406 |
Sec24a,Ldlr,Nr1h3,Med13,Cav1,Fabp3,Ehd1,Il18,Sirt1,Ttc39b,Lipg |
| 2.655e-02 | -3.63 | REACTOME_CELL_CYCLE_CHECKPOINTS | MSigDB lists | REACTOME_CELL_CYCLE_CHECKPOINTS | 109 | 15 | 15632 | 1249 |
Psmd10,Psmb9,Psmb8,Atm,Ccne1,Mdm2,Psma6,Psme2,Psmb10,Mcm6,Mcm10,Ube2e1,Psme1,Psmb6,Cdkn1a |
| 2.655e-02 | -3.63 | MODULE_289 | MSigDB lists | MODULE_289 | 109 | 15 | 15632 | 1249 |
Cxcl1,Rgs3,C3,Fpr2,Fpr1,P2ry14,Ptafr,Adrb2,Ccr3,Adora2a,Dgka,Cx3cr1,Ccr1,Ednrb,Gna15 |
| 2.655e-02 | -3.63 | GO_RECYCLING_ENDOSOME | MSigDB lists | GO_RECYCLING_ENDOSOME | 109 | 15 | 15632 | 1249 |
Sgk3,Rap2c,Atp11b,Slc31a1,Atp11a,Micall2,Rab10,Rab11fip1,Slc39a4,Rffl,Optn,Slc31a2,Rabgef1,Ehd1,Tnf |
| 2.655e-02 | -3.63 | GO_POSITIVE_REGULATION_OF_HORMONE_SECRETION | MSigDB lists | GO_POSITIVE_REGULATION_OF_HORMONE_SECRETION | 109 | 15 | 15632 | 1249 |
Prkce,Edn1,Gpr68,Inhba,Gja1,H2-Eb1,Serp1,Jak2,Hcar2,Nlgn2,Cd38,Lif,Ptger4,Irs2,Hif1a |
| 2.655e-02 | -3.63 | GCACCTT_MIR18A_MIR18B | MSigDB lists | GCACCTT_MIR18A_MIR18B | 109 | 15 | 15632 | 1249 |
Brwd3,Etv6,Triobp,Kdm5b,Sh3bp4,Aebp2,Fchsd2,Nr3c1,D1Ertd622e,Frmd4a,Hif1a,Irf2,Crim1,Igf2bp2,Gclc |
| 2.662e-02 | -3.63 | MODULE_198 | MSigDB lists | MODULE_198 | 281 | 32 | 15632 | 1249 |
Hdac1,Myc,Rbbp8,Jun,Fos,Psmd10,Cenpe,Adar,Pttg1,Ccnd2,Hif1a,Tulp3,Lrp8,Hat1,Trip13,Phlda1,Bcl9,Sap30,Brd2,Ccne1,Junb,Cdkn1a,Gfi1,Ap3m2,Lhx2,Dek,Dr1,Mcm6,Mafg,Dusp5,Stat1,Dck |
| 2.662e-02 | -3.63 | CHANDRAN_METASTASIS_DN | MSigDB lists | CHANDRAN_METASTASIS_DN | 281 | 32 | 15632 | 1249 |
Pde5a,Fgl2,Dusp2,Egr2,Itgb8,Fos,Klf3,Dusp1,Nr4a1,Klf6,Cd38,Pdgfc,Ppm1l,Stat2,Asap3,Atf3,Ier2,Slc30a4,Eya4,Smpdl3b,Zfp36,Btg2,Fosb,Sema3c,Pde4b,Pmepa1,Tnip1,Clcn7,Pcdh7,Ptgs2,Lpar1,Egr3 |
| 2.662e-02 | -3.63 | - | gene3d domains | 3.60.40.10 | 14 | 4 | 8819 | 755 |
Ppm1k,Ppm1l,Phlpp2,Phlpp1 |
| 2.668e-02 | -3.62 | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP | 188 | 23 | 15632 | 1249 |
Trib1,Htr2b,Rims3,Ltbp2,Slc7a8,Slc4a7,Dgka,Mmd,Htra1,Caml,Papss2,Gbe1,Arg2,Palld,Olr1,Pdgfc,Cd14,Extl2,Cd302,Fos,Swap70,Abcc5,Fut8 |
| 2.668e-02 | -3.62 | GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP | MSigDB lists | GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP | 188 | 23 | 15632 | 1249 |
Sav1,Gys1,Slc16a1,Ripk3,Nek6,Coa5,Ubtd2,Cpd,Ppp1r14b,Adam19,Inpp1,Pmepa1,Ldha,Ppa1,Hmox1,Asb13,Pdlim7,Sh3bp4,Kctd12,Slc7a8,Zc3h12c,Itgal,Sipa1l1 |
| 2.668e-02 | -3.62 | GSE16266_CTRL_VS_LPS_STIM_MEF_DN | MSigDB lists | GSE16266_CTRL_VS_LPS_STIM_MEF_DN | 188 | 23 | 15632 | 1249 |
Ciita,Sell,Kmo,Cd74,Il4i1,Gpr84,Hspa1a,Trip10,Mgat1,Cd40,Rgs14,Il1b,Cmpk2,Dcbld2,Serpinb2,Nfkb2,Nr4a3,Sema4a,Oas2,Slamf9,Antxr1,Icosl,Cnn3 |
| 2.668e-02 | -3.62 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_DN | 188 | 23 | 15632 | 1249 |
Dgka,Degs2,Bst1,Psmb8,Lad1,Lgals9,Pmepa1,Sec24b,Gfi1,Mthfd2,Sema4a,Nr4a3,Ms4a6d,Carhsp1,Gsr,Axl,Gpsm2,Rhoh,Mcoln2,Tpx2,Aldh1b1,Socs1,Prnp |
| 2.668e-02 | -3.62 | GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | 188 | 23 | 15632 | 1249 |
Plscr1,Pdlim7,Bst1,Tor3a,Jdp2,Zc3h12c,Gca,Gng12,Casp7,Mtmr14,Ptprj,Rcan1,Serpinb9,Ubtd2,Igsf6,Chst11,Dpy19l1,Itpr1,Cd80,Cd38,Ahr,Mapkapk2,Nlrp3 |
| 2.674e-02 | -3.62 | TGF Beta Signaling Pathway | WikiPathways | WP113 | 52 | 11 | 4813 | 540 |
Lif,Bambi,Nfkb1,Stat3,Fos,Thbs1,Serpine1,Tnf,Inhba,Jun,Stat1 |
| 2.675e-02 | -3.62 | HOEBEKE_LYMPHOID_STEM_CELL_UP | MSigDB lists | HOEBEKE_LYMPHOID_STEM_CELL_UP | 81 | 12 | 15632 | 1249 |
P2ry14,Palld,Evl,Itga4,Hlx,Tnfaip3,Tnfaip2,Osbpl3,Traf5,Bcl6,Tcf4,Irf8 |
| 2.677e-02 | -3.62 | GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_UP | 148 | 19 | 15632 | 1249 |
Dusp1,Sp140,Casp1,Tpst1,Jun,Irgm2,Ggct,Stoml1,Nfkbiz,Socs3,Trib3,Dcp2,Pim1,Socs1,Slc25a22,Clec4e,Pfkl,Zfp319,Hck |
| 2.684e-02 | -3.62 | GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_DN | 178 | 22 | 15632 | 1249 |
Itgal,Vps54,Csrp1,Tshz1,Adora2a,Icosl,Ksr1,Btg2,Kcna3,Adrb2,Ebi3,Larp1,Orai2,Cd82,Irak2,Ifnar1,Ass1,Ap3b1,Sat1,Il4ra,Mark2,Crlf3 |
| 2.684e-02 | -3.62 | GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_UP | 178 | 22 | 15632 | 1249 |
Card6,Irf7,Rhof,Rgs14,Zfp36,Dusp2,Kdm5b,Nfkbie,Pim2,Socs3,Evl,Mtdh,Frmd4a,Nxf1,Rtp4,Nr4a3,Pigv,Mppe1,Acvr1b,Ccdc88b,Tnip1,Znrf1 |
| 2.684e-02 | -3.62 | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | 178 | 22 | 15632 | 1249 |
Syne2,Hspa2,Ly75,Fabp7,Ext1,Casp8,Itgav,Snx10,Axl,5430427O19Rik,Pdgfc,Irak2,Pde3b,Ralgds,Sh3bgrl2,Il1rn,Ttc39b,P2ry14,Il1a,Ldha,Hmox1,Filip1l |
| 2.684e-02 | -3.62 | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_DN | 178 | 22 | 15632 | 1249 |
Egr3,Cd200,Tnip3,Stip1,Irf8,Il10,Tnfsf14,Noc4l,Trip13,Hivep3,Lif,Lrp8,Sdc4,Slc16a1,Plagl2,Tnf,Homer1,Rbbp8,Phgdh,Rab11fip1,Ccdc86,B3gnt5 |
| 2.684e-02 | -3.62 | GSE18893_CTRL_VS_TNF_TREATED_TREG_24H_DN | MSigDB lists | GSE18893_CTRL_VS_TNF_TREATED_TREG_24H_DN | 178 | 22 | 15632 | 1249 |
P2ry13,Casp4,Cenpj,Slfn4,Daam1,Ccl5,Gramd1a,Axl,Tyk2,Lztfl1,4932438A13Rik,Slpi,Irgq,Isg15,Gsta3,Pf4,Klf7,Ncoa7,Pbx1,Ldlr,Slfn3,Osbpl3 |
| 2.684e-02 | -3.62 | GSE23925_DARK_ZONE_VS_NAIVE_BCELL_UP | MSigDB lists | GSE23925_DARK_ZONE_VS_NAIVE_BCELL_UP | 178 | 22 | 15632 | 1249 |
Plekhn1,Slfn3,Slc29a3,Ms4a6d,Kcna3,Nr4a3,Kpna3,Oas1g,Socs3,Oas1a,Casp2,Ddit4,Tifa,Slfn4,Cd164,Zc3hav1,Slc16a1,Sdc2,Errfi1,Acpp,Nfkbia,Sod2 |
| 2.684e-02 | -3.62 | GSE557_WT_VS_I_AB_KO_DC_DN | MSigDB lists | GSE557_WT_VS_I_AB_KO_DC_DN | 178 | 22 | 15632 | 1249 |
Sirt1,Psma6,Ift57,Egr2,Ppp2r5a,Fchsd2,Rab9,Timeless,Mcm9,Lap3,Hsph1,Psip1,Ccne1,Ripk3,Slc25a25,Slc16a1,Slamf7,Slc43a3,Fam133b,Nr4a3,Rars,Dusp5 |
| 2.684e-02 | -3.62 | GSE3982_MAST_CELL_VS_TH2_UP | MSigDB lists | GSE3982_MAST_CELL_VS_TH2_UP | 178 | 22 | 15632 | 1249 |
Dpy19l1,Fcgr4,Plekhf2,Samsn1,Tspan3,Spry2,Caml,Rtn2,Flnb,Bst1,Mid1,Gsr,Ptk2,Hp,Phyh,Clcn7,Extl2,Il1rn,Slc48a1,Clic4,Aff1,Pmepa1 |
| 2.684e-02 | -3.62 | GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_DN | MSigDB lists | GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_DN | 178 | 22 | 15632 | 1249 |
Fam133b,Trib3,Magohb,Psmb6,Tpi1,Fam162a,Pmepa1,Wdr43,Gclc,Ahsa1,Mthfd1l,Ppp1r14b,Slc39a14,Nfkbie,Cers6,Gsr,Adora2a,Ksr1,Gclm,Mdn1,Arl5b,Plscr1 |
| 2.684e-02 | -3.62 | RNA binding | molecular function | GO:0003723 | 1050 | 89 | 20217 | 1400 |
Cpeb4,Eif4g2,Ctu1,Isg20,Tut7,Pnpt1,Magohb,Gtpbp2,Oas1g,Zc3h7a,Oasl2,Ranbp2,Cnp,Prpf4,Helz2,Polr2g,Oas2,Trmt1l,Oas1a,Stau1,Ythdf1,Rbpms,Psma6,Hspa1a,Slfn9,Tlr9,Apobec3,Znfx1,Trim21,Mtdh,Shfl,Arid5a,Lipe,Carhsp1,Noct,Ddx60,Ddx58,Rbm43,Samhd1,Larp1,Rbms2,Zfp36,Zc3h12a,Slpi,Denr,Sbds,Ankrd17,Zbp1,Ifit1,Fubp1,Ikzf1,Oas3,Rrs1,Nxf1,Marf1,Rbms1,Ifit2,Spen,Ddx4,Morc3,Oasl1,Tdrd7,Igf2bp2,Tlr3,Cnot4,Smg7,Mecp2,Rars,Cyfip1,Xrn1,Tra2a,Ifit1bl2,Dcp2,Dhx58,Mdm2,Zc3hav1,Ago3,Ifit1bl1,Eno1,N4bp1,Eif2ak2,Ifih1,Mov10,Myc,Adar,Slfn8,Oas1b,G3bp2,Jmjd6 |
| 2.686e-02 | -3.62 | GOLDRATH_IMMUNE_MEMORY | MSigDB lists | GOLDRATH_IMMUNE_MEMORY | 63 | 10 | 15632 | 1249 |
Traf1,Slc2a1,Prnp,Mcoln2,Plekha5,Kctd12,Il15ra,Prkce,Gpc1,Abcb1a |
| 2.686e-02 | -3.62 | GO_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING | MSigDB lists | GO_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING | 63 | 10 | 15632 | 1249 |
Prnp,Rcan1,Itpr1,Plek,Syk,Atp2b4,Hap1,Cmklr1,Slc9a1,Ccl4 |
| 2.686e-02 | -3.62 | PID_TCR_PATHWAY | MSigDB lists | PID_TCR_PATHWAY | 63 | 10 | 15632 | 1249 |
Dbnl,Prkce,Cd80,Rasgrp1,Ikbkg,Malt1,Nck1,Map3k8,Lcp2,Cd86 |
| 2.686e-02 | -3.62 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | MSigDB lists | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | 63 | 10 | 15632 | 1249 |
Psme2,Psma6,Psmb8,Ube2e1,Psme1,Psmb6,Pttg1,Psmd10,Psmb9,Psmb10 |
| 2.686e-02 | -3.62 | JAZAG_TGFB1_SIGNALING_VIA_SMAD4_DN | MSigDB lists | JAZAG_TGFB1_SIGNALING_VIA_SMAD4_DN | 63 | 10 | 15632 | 1249 |
Bmp2,Phlda1,Pou2f2,Lif,Ccne1,Aim2,Snx10,Ptch1,Pdgfrb,Lcp2 |
| 2.686e-02 | -3.62 | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP | MSigDB lists | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP | 63 | 10 | 15632 | 1249 |
Inhba,Tagap,Vcan,Cd69,Zeb1,Rap2c,Ifi44,Ubtd2,Rgs1,Lox |
| 2.692e-02 | -3.62 | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | 168 | 21 | 15632 | 1249 |
Plaur,Apaf1,Stip1,Ppp2r2a,Mcmbp,Pgk1,Asf1a,Rgs1,Dnajb4,Dnaja2,Mthfr,Gadd45g,Psma6,Stk40,Phlda1,Aftph,Klhl25,Sco1,Cep350,Flt1,Nampt |
| 2.692e-02 | -3.62 | PROTEIN_KINASE_ATP | prosite domains | PS00107 | 375 | 40 | 13278 | 1037 |
Plk2,Pim2,Acvr1,Prkx,Nek6,Hck,Map2k1,Akt3,Ripk3,Axl,Ikbke,Met,Syk,Map3k6,Igf1r,Sgk3,Sik3,Mapkapk2,Acvrl1,Plk3,Lyn,Grk3,Tyk2,Pim3,Src,Jak2,Tlk2,Eif2ak2,Ptk2,Flt1,Acvr1b,Map4k4,Dyrk2,Map2k4,Pdgfrb,Mark2,Kdr,Prkce,Fgr,Pim1 |
| 2.701e-02 | -3.61 | BILD_CTNNB1_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_CTNNB1_ONCOGENIC_SIGNATURE | 72 | 11 | 15632 | 1249 |
Il1a,Plagl1,Dusp5,Dync1h1,Tnfaip3,Vcan,Gng12,Bambi,Chd9,Nr3c1,Trim14 |
| 2.701e-02 | -3.61 | HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN | MSigDB lists | HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN | 72 | 11 | 15632 | 1249 |
St3gal6,Ccnd2,Rcn1,Frmd6,Ccl5,Ifit2,Gbp7,Zyx,Mdn1,Trim21,Stat4 |
| 2.701e-02 | -3.61 | GO_REGULATION_OF_PROTEIN_MATURATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_MATURATION | 72 | 11 | 15632 | 1249 |
Cd55,Rnf139,C3,Thbs1,Ppp1r15a,Nlrc4,Birc2,Serpine1,Birc3,Mdm2,Inpp5b |
| 2.701e-02 | -3.61 | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN | MSigDB lists | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN | 72 | 11 | 15632 | 1249 |
Pdlim7,Gys1,Gpr35,Gcnt2,Il15ra,Plagl2,Eno2,Homer1,Higd1a,Gbe1,Serpine1 |
| 2.701e-02 | -3.61 | GO_NEGATIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS | 72 | 11 | 15632 | 1249 |
Gfi1,Il1b,Hcar2,Sirt1,Pde3b,Bmp2,Ppp2r5a,Pdgfb,Trib3,Nfkb1,Tnf |
| 2.701e-02 | -3.61 | LIU_NASOPHARYNGEAL_CARCINOMA | MSigDB lists | LIU_NASOPHARYNGEAL_CARCINOMA | 72 | 11 | 15632 | 1249 |
H2-Q6,Ednrb,H2-Q4,Tapbp,Peli1,Cd74,Etnk1,H2-Q7,Dnase1l3,Rap2c,Inpp1 |
| 2.705e-02 | -3.61 | HS-GAG biosynthesis | REACTOME pathways | R-MMU-2022928 | 27 | 6 | 8608 | 757 |
Ext1,Gpc1,Sdc4,Sdc2,Agrn,Sdc1 |
| 2.705e-02 | -3.61 | GO_PROTEIN_LIPID_COMPLEX_BINDING | MSigDB lists | GO_PROTEIN_LIPID_COMPLEX_BINDING | 22 | 5 | 15632 | 1249 |
Scarf1,Msr1,Ldlr,Lrp8,Thbs1 |
| 2.705e-02 | -3.61 | GO_RESPONSE_TO_IMMOBILIZATION_STRESS | MSigDB lists | GO_RESPONSE_TO_IMMOBILIZATION_STRESS | 22 | 5 | 15632 | 1249 |
Fos,Ppp1r15a,Keap1,Ptger4,Lrp11 |
| 2.705e-02 | -3.61 | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_DN | MSigDB lists | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_DN | 22 | 5 | 15632 | 1249 |
Egr1,Lcp2,Irf8,Cd69,Hspa2 |
| 2.705e-02 | -3.61 | HASLINGER_B_CLL_WITH_13Q14_DELETION | MSigDB lists | HASLINGER_B_CLL_WITH_13Q14_DELETION | 22 | 5 | 15632 | 1249 |
Rbms2,Dusp8,Ldlr,Trim13,Arl4a |
| 2.705e-02 | -3.61 | YIH_RESPONSE_TO_ARSENITE_C1 | MSigDB lists | YIH_RESPONSE_TO_ARSENITE_C1 | 22 | 5 | 15632 | 1249 |
Fas,Cflar,Ptk2,Nat2,Zfp36 |
| 2.705e-02 | -3.61 | CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_UP | 22 | 5 | 15632 | 1249 |
Kmo,Calcrl,Isg15,Fcgr2b,Stat1 |
| 2.705e-02 | -3.61 | PID_PDGFRA_PATHWAY | MSigDB lists | PID_PDGFRA_PATHWAY | 22 | 5 | 15632 | 1249 |
Jun,Cav1,Fos,Itgav,Crkl |
| 2.705e-02 | -3.61 | GO_ERYTHROCYTE_DEVELOPMENT | MSigDB lists | GO_ERYTHROCYTE_DEVELOPMENT | 22 | 5 | 15632 | 1249 |
Jmjd6,Bcl6,Klf2,Tmod3,Arid4a |
| 2.705e-02 | -3.61 | MODULE_71 | MSigDB lists | MODULE_71 | 22 | 5 | 15632 | 1249 |
Slc7a2,Slc16a3,Ltbp2,Slc16a1,Slc7a5 |
| 2.705e-02 | -3.61 | RAHMAN_TP53_TARGETS_PHOSPHORYLATED | MSigDB lists | RAHMAN_TP53_TARGETS_PHOSPHORYLATED | 22 | 5 | 15632 | 1249 |
Psmb6,Ppa1,Magohb,Phgdh,Actb |
| 2.705e-02 | -3.61 | GO_REGULATION_OF_ISOTYPE_SWITCHING | MSigDB lists | GO_REGULATION_OF_ISOTYPE_SWITCHING | 22 | 5 | 15632 | 1249 |
Bcl6,Cd40,Il10,Tnfsf4,Clcf1 |
| 2.705e-02 | -3.61 | GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY | 22 | 5 | 15632 | 1249 |
Il12b,Il12rb1,H2-Q6,H2-Q4,H2-Q7 |
| 2.705e-02 | -3.61 | BIOCARTA_SPPA_PATHWAY | MSigDB lists | BIOCARTA_SPPA_PATHWAY | 22 | 5 | 15632 | 1249 |
Syk,Pla2g4a,Ptk2,Src,Map2k1 |
| 2.705e-02 | -3.61 | KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES | MSigDB lists | KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES | 22 | 5 | 15632 | 1249 |
St3gal6,B3gnt5,B4galt4,Gcnt2,St3gal3 |
| 2.705e-02 | -3.61 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_UP | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_UP | 22 | 5 | 15632 | 1249 |
Dpy19l1,Fas,Pdk3,Csf1,Dram1 |
| 2.705e-02 | -3.61 | GO_REGULATION_OF_NUCLEASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_NUCLEASE_ACTIVITY | 22 | 5 | 15632 | 1249 |
Oas1g,Oas3,Tcea1,Sirt1,Oas1a |
| 2.706e-02 | -3.61 | 4.1m | smart domains | SM00294 | 14 | 4 | 9567 | 823 |
Sdc1,Sdc4,Gypc,Sdc2 |
| 2.710e-02 | -3.61 | TNFR1-induced proapoptotic signaling | REACTOME pathways | R-MMU-5357786 | 8 | 3 | 8608 | 757 |
Traf2,Tnf,Tnfaip3 |
| 2.710e-02 | -3.61 | VEGF binds to VEGFR leading to receptor dimerization | REACTOME pathways | R-MMU-195399 | 8 | 3 | 8608 | 757 |
Vegfc,Kdr,Flt1 |
| 2.710e-02 | -3.61 | Pre-NOTCH Transcription and Translation | REACTOME pathways | R-MMU-1912408 | 8 | 3 | 8608 | 757 |
Ccnd1,Notch1,Kat2b |
| 2.710e-02 | -3.61 | VEGF ligand-receptor interactions | REACTOME pathways | R-MMU-194313 | 8 | 3 | 8608 | 757 |
Kdr,Flt1,Vegfc |
| 2.710e-02 | -3.61 | Urea cycle | REACTOME pathways | R-MMU-70635 | 8 | 3 | 8608 | 757 |
Nmral1,Ass1,Arg2 |
| 2.714e-02 | -3.61 | BIOCARTA_HIF_PATHWAY | MSigDB lists | BIOCARTA_HIF_PATHWAY | 15 | 4 | 15632 | 1249 |
Jun,Hif1a,Ldha,Edn1 |
| 2.714e-02 | -3.61 | GO_CELLULAR_RESPONSE_TO_LEPTIN_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_LEPTIN_STIMULUS | 15 | 4 | 15632 | 1249 |
Sirt1,Pid1,Nr4a3,Stat3 |
| 2.714e-02 | -3.61 | GO_POLYAMINE_METABOLIC_PROCESS | MSigDB lists | GO_POLYAMINE_METABOLIC_PROCESS | 15 | 4 | 15632 | 1249 |
Sat1,Smox,Srm,Odc1 |
| 2.714e-02 | -3.61 | GO_PHOSPHOTYROSINE_BINDING | MSigDB lists | GO_PHOSPHOTYROSINE_BINDING | 15 | 4 | 15632 | 1249 |
Fgr,Acp2,Samsn1,Stap1 |
| 2.714e-02 | -3.61 | REACTOME_METABOLISM_OF_POLYAMINES | MSigDB lists | REACTOME_METABOLISM_OF_POLYAMINES | 15 | 4 | 15632 | 1249 |
Odc1,Srm,Sat1,Smox |
| 2.714e-02 | -3.61 | LEE_NAIVE_T_LYMPHOCYTE | MSigDB lists | LEE_NAIVE_T_LYMPHOCYTE | 15 | 4 | 15632 | 1249 |
Atp10a,Upp1,Tagap,I830077J02Rik |
| 2.714e-02 | -3.61 | GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 15 | 4 | 15632 | 1249 |
Flt1,Itga5,Hif1a,Il1b |
| 2.714e-02 | -3.61 | GO_NEUROTROPHIN_TRK_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_NEUROTROPHIN_TRK_RECEPTOR_SIGNALING_PATHWAY | 15 | 4 | 15632 | 1249 |
Hap1,Ddit4,Casp3,Src |
| 2.714e-02 | -3.61 | GO_RESPONSE_TO_VITAMIN_E | MSigDB lists | GO_RESPONSE_TO_VITAMIN_E | 15 | 4 | 15632 | 1249 |
Hmgcs1,Eif2ak2,Ccne1,Ccnd1 |
| 2.714e-02 | -3.61 | BIOCARTA_IL3_PATHWAY | MSigDB lists | BIOCARTA_IL3_PATHWAY | 15 | 4 | 15632 | 1249 |
Jak2,Stat5a,Map2k1,Fos |
| 2.714e-02 | -3.61 | GO_INTERLEUKIN_1_RECEPTOR_BINDING | MSigDB lists | GO_INTERLEUKIN_1_RECEPTOR_BINDING | 15 | 4 | 15632 | 1249 |
Tlr9,Il1rn,Il1b,Il1a |
| 2.714e-02 | -3.61 | HUMMERICH_BENIGN_SKIN_TUMOR_UP | MSigDB lists | HUMMERICH_BENIGN_SKIN_TUMOR_UP | 15 | 4 | 15632 | 1249 |
Glrx,Slpi,Usp25,S100a8 |
| 2.714e-02 | -3.61 | GO_APOPTOTIC_PROCESS_INVOLVED_IN_MORPHOGENESIS | MSigDB lists | GO_APOPTOTIC_PROCESS_INVOLVED_IN_MORPHOGENESIS | 15 | 4 | 15632 | 1249 |
Fzd5,Notch1,Bcl2l11,Ppp2r1b |
| 2.714e-02 | -3.61 | GO_NEGATIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | 15 | 4 | 15632 | 1249 |
Il6,Mefv,Mul1,Il10 |
| 2.714e-02 | -3.61 | HAHTOLA_MYCOSIS_FUNGOIDES_UP | MSigDB lists | HAHTOLA_MYCOSIS_FUNGOIDES_UP | 15 | 4 | 15632 | 1249 |
Sod2,Stat1,Mmp9,Sik3 |
| 2.714e-02 | -3.61 | GO_NEGATIVE_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION | 15 | 4 | 15632 | 1249 |
Src,Thbs1,Mmp14,Acvrl1 |
| 2.714e-02 | -3.61 | GO_ATRIOVENTRICULAR_VALVE_MORPHOGENESIS | MSigDB lists | GO_ATRIOVENTRICULAR_VALVE_MORPHOGENESIS | 15 | 4 | 15632 | 1249 |
Notch1,Acvr1,Mdm2,Bmp2 |
| 2.714e-02 | -3.61 | GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION | 15 | 4 | 15632 | 1249 |
Cd34,Ezr,Prnp,Tnfaip3 |
| 2.714e-02 | -3.61 | GO_NITRIC_OXIDE_SYNTHASE_BINDING | MSigDB lists | GO_NITRIC_OXIDE_SYNTHASE_BINDING | 15 | 4 | 15632 | 1249 |
Actb,Cav1,Cd74,Atp2b4 |
| 2.714e-02 | -3.61 | BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN | 15 | 4 | 15632 | 1249 |
Trib1,Il4ra,Ier3,Maff |
| 2.714e-02 | -3.61 | KANG_FLUOROURACIL_RESISTANCE_DN | MSigDB lists | KANG_FLUOROURACIL_RESISTANCE_DN | 15 | 4 | 15632 | 1249 |
Slc2a1,Flnb,Ldlr,Ddit4 |
| 2.714e-02 | -3.61 | GO_PROTEIN_HYDROXYLATION | MSigDB lists | GO_PROTEIN_HYDROXYLATION | 15 | 4 | 15632 | 1249 |
Egln3,Jmjd6,P4ha2,P4ha1 |
| 2.714e-02 | -3.61 | GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_BINDING | MSigDB lists | GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_BINDING | 15 | 4 | 15632 | 1249 |
Msr1,Scarf1,Thbs1,Ldlr |
| 2.714e-02 | -3.61 | GO_RESPONSE_TO_SALT | MSigDB lists | GO_RESPONSE_TO_SALT | 15 | 4 | 15632 | 1249 |
Ppp1r15a,Zc3h12a,Edn1,Ptger4 |
| 2.714e-02 | -3.61 | GO_POSITIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION | 15 | 4 | 15632 | 1249 |
Cd34,Thbs1,Ptgs2,Cx3cl1 |
| 2.714e-02 | -3.61 | DAZARD_UV_RESPONSE_CLUSTER_G3 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G3 | 15 | 4 | 15632 | 1249 |
Ppp1r15a,Tnfaip3,Prdm1,Brd2 |
| 2.714e-02 | -3.61 | GO_SERTOLI_CELL_DEVELOPMENT | MSigDB lists | GO_SERTOLI_CELL_DEVELOPMENT | 15 | 4 | 15632 | 1249 |
Arid4a,Fndc3a,Icam1,Sdc1 |
| 2.718e-02 | -3.61 | NFAT_Q6 | MSigDB lists | NFAT_Q6 | 219 | 26 | 15632 | 1249 |
Etv5,Zbtb5,Prrg4,Lif,Acvr1,Ifnb1,Gadd45g,Irf4,Edn1,Ankrd17,Parp8,Zhx2,Phf6,Irf1,Nr4a3,Kif3c,Pik3cd,Cpeb4,Snx2,Pdgfb,Arl5b,Cd274,Plod2,Jarid2,Jdp2,Map4k4 |
| 2.724e-02 | -3.60 | cell leading edge | cellular component | GO:0031252 | 380 | 36 | 20747 | 1409 |
Ddx58,Ezr,Arf4,Phactr4,Myo10,Pdlim7,Itga5,Scimp,Ptk2,Fgr,Asap3,Src,Cacna1d,Lmo4,Psd,Palld,Mtmr14,Carmil1,Dbnl,Vasp,Itgav,Evl,Adora2a,Psd4,Pdpn,Kitl,Tmod3,Fscn1,Cyth3,Spata13,Ptprj,Plek,Syne2,Myadm,Antxr1,Cyfip1 |
| 2.724e-02 | -3.60 | mouse chr14|14 D3 | chromosome location | mouse chr14|14 D3 | 49 | 7 | 24173 | 1464 |
Rubcnl,Rgcc,Lrch1,Lacc1,Dgkh,Epsti1,Cysltr2 |
| 2.730e-02 | -3.60 | Bladder cancer | KEGG pathways | ko05219 | 41 | 8 | 7931 | 713 |
Thbs1,Map2k1,Myc,Cdkn1a,Mdm2,Src,Mmp9,Ccnd1 |
| 2.730e-02 | -3.60 | Bladder cancer | KEGG pathways | mmu05219 | 41 | 8 | 7931 | 713 |
Thbs1,Myc,Map2k1,Cdkn1a,Src,Mdm2,Mmp9,Ccnd1 |
| 2.742e-02 | -3.60 | regulation of RNA stability | biological process | GO:0043487 | 106 | 13 | 20694 | 1406 |
Carhsp1,Dcp2,Zfp36,Myd88,Noct,Tnfrsf1b,Zc3h12a,Mapkapk2,Mov10,Larp1,Tent4a,Tent2,Plekhn1 |
| 2.742e-02 | -3.60 | response to purine-containing compound | biological process | GO:0014074 | 106 | 13 | 20694 | 1406 |
Rapgef2,Junb,Ezr,Casp1,Il1b,Hmgcs1,Stat1,Itpr1,Sell,P2ry12,Jun,Adora2a,Ahr |
| 2.749e-02 | -3.59 | rhythmic process | biological process | GO:0048511 | 257 | 26 | 20694 | 1406 |
Egr2,Gfpt1,Nfil3,Nfkb2,Nos2,Stat5a,Noct,Src,Hdac1,Timeless,Pla2g4a,Ass1,Pml,Nampt,Igf1r,Ahr,Egr1,Fas,Cdk5r1,Inhba,Relb,Kat2b,Sirt1,Kdm5b,Prokr1,Axl |
| 2.752e-02 | -3.59 | thioesterase binding | molecular function | GO:0031996 | 10 | 3 | 20217 | 1400 |
Traf1,Traf2,Traf5 |
| 2.752e-02 | -3.59 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | molecular function | GO:0016668 | 10 | 3 | 20217 | 1400 |
Gsr,Txnrd1,Pgk1 |
| 2.752e-02 | -3.59 | low-density lipoprotein particle receptor activity | molecular function | GO:0005041 | 10 | 3 | 20217 | 1400 |
Olr1,Lrp8,Ldlr |
| 2.755e-02 | -3.59 | GO_TRANSITION_METAL_ION_TRANSPORT | MSigDB lists | GO_TRANSITION_METAL_ION_TRANSPORT | 100 | 14 | 15632 | 1249 |
Cutc,Slc39a13,Slc30a1,Slc30a4,Slc31a1,Cox17,Slc39a14,Atp13a1,Slc39a4,Cp,Sco1,Atp6v1d,Slc31a2,Slc25a37 |
| 2.755e-02 | -3.59 | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP | MSigDB lists | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP | 100 | 14 | 15632 | 1249 |
Fos,Tnfsf14,Sod2,Rabgef1,Ogfrl1,Gclm,Sphk1,Ier3,Phip,Egr1,Smox,Hck,Pdgfc,Gng11 |
| 2.756e-02 | -3.59 | CEBP_Q2 | MSigDB lists | CEBP_Q2 | 209 | 25 | 15632 | 1249 |
Nfil3,H3f3b,Clic4,Ttc39b,Adrb2,Csf3,Ube2e2,Slc25a12,Pdgfb,Nrp2,Asah2,Jarid2,Angpt1,Rab3ip,Spred1,Gys1,Pde3b,Lipg,Nfkbiz,Stk40,Rbpms,Pla2g4a,Stat3,Tcf4,Nfkbia |
| 2.756e-02 | -3.59 | CIZ_01 | MSigDB lists | CIZ_01 | 209 | 25 | 15632 | 1249 |
Flrt3,Tcf4,Ccnd1,Ift57,Gadd45g,Zfp513,Ccnd2,Batf,Rbm43,Klf7,Tnks1bp1,Rims3,Bcl9,Pdgfb,Atxn7l1,Zscan29,Tdrd7,Dgka,Phf6,Tmem229b,Pcdh7,Ppp2r1b,Col27a1,Pkp4,H3f3b |
| 2.756e-02 | -3.59 | disordered domain specific binding | molecular function | GO:0097718 | 34 | 6 | 20217 | 1400 |
Hspa2,Mdm2,Keap1,Gja1,Hspa1a,Ezr |
| 2.762e-02 | -3.59 | GO_NEGATIVE_REGULATION_OF_LOCOMOTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LOCOMOTION | 240 | 28 | 15632 | 1249 |
Sema3c,Serpine1,Dach1,Rabgef1,Spint2,Trim26,Trib1,Sema4a,Ptprj,Sema4c,Ptger4,Hmox1,Rap2c,Clic4,Thbs1,Timp1,Cited2,Ptpn2,Cx3cr1,Itgav,Ccl12,Acvrl1,Stat3,Stap1,Trim12c,Evl,Abr,Notch1 |
| 2.762e-02 | -3.59 | AML1_Q6 | MSigDB lists | AML1_Q6 | 240 | 28 | 15632 | 1249 |
Rilpl1,Mmp13,Sirt1,Hivep3,Dgka,Cd69,Jdp2,Notch2,Acsl5,Rgs1,Tnfsf4,Rnf19b,Frmd4a,Sema4a,Egr2,Slc15a3,Mmp14,Nr4a1,Trmt1l,Col4a2,Batf,Hinfp,Smg7,Pde3b,Hlx,Prrg4,Stat2,Pigv |
| 2.762e-02 | -3.59 | AML1_01 | MSigDB lists | AML1_01 | 240 | 28 | 15632 | 1249 |
Egr2,Slc15a3,Mmp14,Trmt1l,Nr4a1,Smg7,Pde3b,Col4a2,Hinfp,Batf,Pigv,Stat2,Prrg4,Hlx,Dgka,Cd69,Hivep3,Mmp13,Sirt1,Rilpl1,Jdp2,Rgs1,Acsl5,Notch2,Frmd4a,Sema4a,Tnfsf4,Rnf19b |
| 2.768e-02 | -3.59 | positive regulation of ATP metabolic process | biological process | GO:1903580 | 44 | 7 | 20694 | 1406 |
Pid1,Pgk1,Map2k1,Nupr1,Htr2a,Myc,Stat3 |
| 2.768e-02 | -3.59 | regulation of polysaccharide metabolic process | biological process | GO:0032881 | 44 | 7 | 20694 | 1406 |
Dyrk2,Gfpt1,Pdgfb,Ptger4,Rubcnl,Nfkb1,Irs2 |
| 2.768e-02 | -3.59 | lung epithelium development | biological process | GO:0060428 | 44 | 7 | 20694 | 1406 |
Errfi1,Foxp4,Klf2,Sav1,Map2k1,Hmga2,Gpsm2 |
| 2.768e-02 | -3.59 | ribonuclease activity | molecular function | GO:0004540 | 115 | 14 | 20217 | 1400 |
Noct,Rcl1,Slfn8,Dcp2,Isg20,Pnpt1,Xrn1,Rnaset2a,Usb1,Slfn9,Helz2,Ago3,Zc3h12a,Rnaset2b |
| 2.775e-02 | -3.58 | NACHT_NTPase | interpro domains | IPR007111 | 33 | 6 | 19984 | 1430 |
Nlrc4,Nlrc5,Nod2,Nod1,Nlrp3,Ciita |
| 2.779e-02 | -3.58 | GO_NEGATIVE_REGULATION_OF_CHEMOTAXIS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CHEMOTAXIS | 46 | 8 | 15632 | 1249 |
Notch1,Thbs1,Stap1,Sema4a,Ptpn2,Sema3c,Ccl12,Sema4c |
| 2.779e-02 | -3.58 | GO_PROTEIN_K48_LINKED_UBIQUITINATION | MSigDB lists | GO_PROTEIN_K48_LINKED_UBIQUITINATION | 46 | 8 | 15632 | 1249 |
Peli1,Rffl,Znrf1,Bfar,Rnf34,Tnfaip3,Ube2e2,Ube2e1 |
| 2.779e-02 | -3.58 | GO_RESPONSE_TO_AXON_INJURY | MSigDB lists | GO_RESPONSE_TO_AXON_INJURY | 46 | 8 | 15632 | 1249 |
Flrt3,Max,Lyn,Jun,Tspo,Jak2,Arf4,Tnc |
| 2.779e-02 | -3.58 | GO_THYMUS_DEVELOPMENT | MSigDB lists | GO_THYMUS_DEVELOPMENT | 46 | 8 | 15632 | 1249 |
Pbx1,Ripk3,Bcl2l11,Crkl,Jarid2,Lmo4,Map2k1,Psmb9 |
| 2.779e-02 | -3.58 | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_UP | MSigDB lists | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_UP | 46 | 8 | 15632 | 1249 |
Il10,P4ha1,Prdm1,Casp7,Dpy19l1,Ldlr,Tnfrsf8,Irf4 |
| 2.779e-02 | -3.58 | GO_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_POTENTIAL | MSigDB lists | GO_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_POTENTIAL | 46 | 8 | 15632 | 1249 |
Gclm,Tspo,Gclc,Kdr,Pid1,Mul1,Src,Casp1 |
| 2.779e-02 | -3.58 | GO_ACTIN_FILAMENT_BUNDLE | MSigDB lists | GO_ACTIN_FILAMENT_BUNDLE | 46 | 8 | 15632 | 1249 |
Micall2,Fscn1,Pdlim7,Flnb,Daam1,Zyx,Ptk2,Cnn2 |
| 2.779e-02 | -3.58 | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP | MSigDB lists | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP | 46 | 8 | 15632 | 1249 |
Srm,Asns,Pttg1,Dnaja1,Ahsa1,Myc,Slc7a5,Rbpms |
| 2.781e-02 | -3.58 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | 261 | 30 | 15632 | 1249 |
Egr3,Slc25a22,Ak4,Tnip1,Rap2c,Jak2,Zhx2,Igf1r,Jarid2,Sik3,Flnb,Sap30,Smpdl3b,Papss2,Irs2,Sgk3,Sav1,Gnb4,Tsku,Aff1,Atp2b4,Ass1,P4ha2,Rhbdf2,Rbbp8,Tiparp,Rhoq,Myc,Ppp2r5a,Vcan |
| 2.782e-02 | -3.58 | cell part morphogenesis | biological process | GO:0032990 | 507 | 46 | 20694 | 1406 |
Nes,Scn1b,Dst,Cyfip1,Lrp4,Vasp,Sema3c,Nrp2,Lhx2,Map4k4,Map2k1,Dock10,Sema4a,Ptch1,Gja1,Flrt3,Dbnl,Nr4a3,Cdk5r1,Klf7,Palld,Notch1,Pid1,Kif5c,Stxbp1,Egr2,Kdr,Pnpt1,Snx2,Adora2a,Evl,Sdc2,Cnp,Ntng2,Ext1,Tsku,Igf1r,Rab10,Lrp8,Flrt2,Uchl1,Actb,Itga4,Nectin2,Agrn,Ptk2 |
| 2.783e-02 | -3.58 | APC/C:Cdc20 mediated degradation of Securin | REACTOME pathways | R-MMU-174154 | 66 | 11 | 8608 | 757 |
Psmb9,Psmb8,Psmb10,Psma6,Psmb6,Psme2,Psme2b,Pttg1,Ube2e1,Psmd10,Psme1 |
| 2.786e-02 | -3.58 | Notch | interpro domains | IPR008297 | 4 | 2 | 19984 | 1430 |
Notch2,Notch1 |
| 2.786e-02 | -3.58 | PKHA4/5/6/7_PH | interpro domains | IPR040392 | 4 | 2 | 19984 | 1430 |
Plekha4,Plekha5 |
| 2.786e-02 | -3.58 | POLO_box_dom_sf | interpro domains | IPR036947 | 4 | 2 | 19984 | 1430 |
Plk3,Plk2 |
| 2.786e-02 | -3.58 | Metalthion_dom_sf | interpro domains | IPR017854 | 4 | 2 | 19984 | 1430 |
Mt1,Mt2 |
| 2.786e-02 | -3.58 | THF_DH/CycHdrlase_cat_dom | interpro domains | IPR020630 | 4 | 2 | 19984 | 1430 |
Mthfd1l,Mthfd2 |
| 2.786e-02 | -3.58 | FERM_F2 | interpro domains | IPR041046 | 4 | 2 | 19984 | 1430 |
Jak2,Tyk2 |
| 2.786e-02 | -3.58 | Metalthion_vert | interpro domains | IPR000006 | 4 | 2 | 19984 | 1430 |
Mt2,Mt1 |
| 2.786e-02 | -3.58 | Reticulon | interpro domains | IPR003388 | 4 | 2 | 19984 | 1430 |
Rtn1,Rtn2 |
| 2.786e-02 | -3.58 | Atypical_DUSP_famB | interpro domains | IPR020420 | 4 | 2 | 19984 | 1430 |
Dusp14,Dusp1 |
| 2.786e-02 | -3.58 | POLO_box_1 | interpro domains | IPR033701 | 4 | 2 | 19984 | 1430 |
Plk3,Plk2 |
| 2.786e-02 | -3.58 | DnaJ | interpro domains | IPR012724 | 4 | 2 | 19984 | 1430 |
Dnaja2,Dnaja1 |
| 2.786e-02 | -3.58 | THF_DH/CycHdrlase_NAD-bd_dom | interpro domains | IPR020631 | 4 | 2 | 19984 | 1430 |
Mthfd1l,Mthfd2 |
| 2.786e-02 | -3.58 | Metalthion | interpro domains | IPR003019 | 4 | 2 | 19984 | 1430 |
Mt2,Mt1 |
| 2.786e-02 | -3.58 | Notch_NODP_dom | interpro domains | IPR011656 | 4 | 2 | 19984 | 1430 |
Notch2,Notch1 |
| 2.786e-02 | -3.58 | Sec24-like_trunk_dom | interpro domains | IPR041742 | 4 | 2 | 19984 | 1430 |
Sec24a,Sec24b |
| 2.786e-02 | -3.58 | RHIM_dom | interpro domains | IPR025735 | 4 | 2 | 19984 | 1430 |
Ripk3,Zbp1 |
| 2.786e-02 | -3.58 | Jak1_PHL_dom | interpro domains | IPR041381 | 4 | 2 | 19984 | 1430 |
Jak2,Tyk2 |
| 2.786e-02 | -3.58 | Rege-1_UBA-like | interpro domains | IPR040546 | 4 | 2 | 19984 | 1430 |
Zc3h12a,Zc3h12c |
| 2.786e-02 | -3.58 | Calponin/LIMCH1 | interpro domains | IPR001997 | 4 | 2 | 19984 | 1430 |
Cnn3,Cnn2 |
| 2.786e-02 | -3.58 | MCT | interpro domains | IPR004743 | 4 | 2 | 19984 | 1430 |
Slc16a1,Slc16a3 |
| 2.786e-02 | -3.58 | Metalthion_vert_metal_BS | interpro domains | IPR018064 | 4 | 2 | 19984 | 1430 |
Mt1,Mt2 |
| 2.786e-02 | -3.58 | Tyr_kinase_non-rcpt_Jak/Tyk2 | interpro domains | IPR016251 | 4 | 2 | 19984 | 1430 |
Tyk2,Jak2 |
| 2.786e-02 | -3.58 | Metalthion_dom_sf_vert | interpro domains | IPR023587 | 4 | 2 | 19984 | 1430 |
Mt1,Mt2 |
| 2.786e-02 | -3.58 | Iml2/TPR_39 | interpro domains | IPR019412 | 4 | 2 | 19984 | 1430 |
Ttc39c,Ttc39b |
| 2.786e-02 | -3.58 | Notch_NOD_dom | interpro domains | IPR010660 | 4 | 2 | 19984 | 1430 |
Notch1,Notch2 |
| 2.786e-02 | -3.58 | FERM_F1 | interpro domains | IPR041155 | 4 | 2 | 19984 | 1430 |
Tyk2,Jak2 |
| 2.786e-02 | -3.58 | THF_DH/CycHdrlase | interpro domains | IPR000672 | 4 | 2 | 19984 | 1430 |
Mthfd1l,Mthfd2 |
| 2.789e-02 | -3.58 | HAMAI_APOPTOSIS_VIA_TRAIL_UP | MSigDB lists | HAMAI_APOPTOSIS_VIA_TRAIL_UP | 531 | 55 | 15632 | 1249 |
Ifi209,Birc2,Tcf4,Rbbp8,Ifi205,Itpr1,Hsph1,Ifi213,Dock10,Phgdh,Ifih1,Myo10,Daam1,Snx10,AA467197,Ppp2r3a,Snx2,Ifi208,Nmi,Stxbp3,St3gal1,Cd55,Tcea1,Snapc1,Dek,Dnaja1,Itgav,Cenpe,Mid1,Optn,Ap3b1,Bbx,Rai14,Papss2,Ifi214,Usp25,Palld,Ifi207,Mndal,Cep350,Vezt,Sema3c,Atm,Ifi203,Usp12,Jag1,Mmd,Ppp4r2,Ifi211,Ifi204,Stat1,Socs3,Idi1,Tax1bp1,Zcchc2 |
| 2.789e-02 | -3.58 | GO_DNA_INTEGRITY_CHECKPOINT | MSigDB lists | GO_DNA_INTEGRITY_CHECKPOINT | 129 | 17 | 15632 | 1249 |
Nek6,Mapkapk2,Pml,Plk3,Plagl1,Hinfp,Tnks1bp1,Cdkn1a,Atm,Rbbp8,Cenpj,Plk2,Btg2,Casp2,Ccnd1,Cnot4,Mdm2 |
| 2.789e-02 | -3.58 | BROWNE_HCMV_INFECTION_16HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_16HR_UP | 199 | 24 | 15632 | 1249 |
Abcb1a,Nat2,Ifi44,Dtnb,Hspa2,Crlf3,Bmp2,Slc16a1,Rgs3,Clcn5,Prpf4,Slc30a4,Arl4a,Sap30,Plscr1,Eno2,Rel,Fubp1,Whamm,Dr1,Rnf19b,Nr4a3,Lyn,St7 |
| 2.789e-02 | -3.58 | GO_DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS | MSigDB lists | GO_DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS | 199 | 24 | 15632 | 1249 |
Icam1,Sdc1,Nupr1,Fas,Ahr,Tiparp,Bcl2l11,Insl6,Ccnd1,Mmp14,Pla2g4a,Arid5b,Acvr1b,Fndc3a,Hmgcs1,Tlr3,Kitl,Ccne1,Arid4a,Dach1,Casp2,Inhba,Mmp13,Sirt1 |
| 2.791e-02 | -3.58 | mouse chr19 | chromosome location | mouse chr19 | 195 | 19 | 24173 | 1464 |
Nxf1,Mark2,Psd,Gda,Jak2,Ehd1,Minpp1,Nfkb2,Pcx,Papss2,Casp7,Fam111a,Fas,Prdx5,Hhex,Psat1,Cdc42ep2,Ccdc86,Ifit1bl1 |
| 2.792e-02 | -3.58 | BH2 | prosite domains | PS01258 | 9 | 3 | 13278 | 1037 |
Bcl2a1a,Bcl2a1b,Bcl2a1d |
| 2.792e-02 | -3.58 | JMJN | prosite domains | PS51183 | 9 | 3 | 13278 | 1037 |
Jarid2,Kdm4a,Kdm5b |
| 2.792e-02 | -3.58 | BH1 | prosite domains | PS01080 | 9 | 3 | 13278 | 1037 |
Bcl2a1a,Bcl2a1d,Bcl2a1b |
| 2.792e-02 | -3.58 | PDGF_2 | prosite domains | PS50278 | 9 | 3 | 13278 | 1037 |
Pdgfc,Vegfc,Pdgfb |
| 2.794e-02 | -3.58 | small molecule metabolic process | biological process | GO:0044281 | 1450 | 117 | 20694 | 1406 |
Il1b,Tet2,Acsl5,Txnrd1,Plcl2,Extl2,Nr4a3,Adhfe1,Chst11,Pcx,Il4i1,Cemip2,Acod1,Hk2,Samhd1,Tpi1,Dck,Ldha,Grk3,Degs2,Mgat1,Phgdh,Ptgs2,Oasl2,Hif1a,Acsl1,Pgm1,Upp1,Gclc,Nt5c3,Txn1,Plod2,C3,Cd74,Tha1,P4ha1,Plod3,Lipg,Hk1,Hmgcs1,Wars,Fut8,Pfkl,Acpp,Asah2,Pla2g4a,Gch1,Nampt,Eno2,Atf3,Serp1,Angpt1,Psat1,Dse,Mthfd2,Me1,Tnf,Inpp5b,Gfpt1,Plaat3,Syk,Pdss1,Hk3,Mthfd1l,Tlr2,Plpp1,Ptges,Pgk1,Lipe,Sphk1,Aoah,Ass1,Ampd3,Ldlr,Pdk3,Odc1,Cmpk2,Asns,Itpkc,Hsd17b7,Gpd2,Nos2,Phyh,Arg2,Ptafr,Oas1a,Mthfr,Ak4,P4ha2,Ero1l,Dhrs9,Nr1h3,Enpp4,Kmo,Ch25h,Gda,Gclm,Myc,Pde5a,Il15,Esd,Papss2,Carmil1,Rhoq,Edn1,Prkar2b,Tnfsf4,Cnp,Gk,Rars,Pdpn,Stat5a,Egln3,Inpp1,Apobec3,Mecp2,Hdc |
| 2.794e-02 | -3.58 | GO_REGULATION_OF_CELL_MORPHOGENESIS | MSigDB lists | GO_REGULATION_OF_CELL_MORPHOGENESIS | 509 | 53 | 15632 | 1249 |
Bmp2,Hck,Myo10,Notch1,Lif,Fgr,Icam1,Rhoq,Rab21,Tbc1d1,Glipr2,Phldb1,Lrp4,Src,Bambi,Gcnt2,Fmnl2,Atp10a,Cdc42ep4,Tbc1d13,Hap1,Vasn,Rapgef2,Brwd3,Myadm,Sipa1l1,Map2k1,Cdc42ep2,Mark2,Lrp8,Cdk5r1,Mul1,Phip,Ccl2,Il6,Pdpn,Triobp,Ifrd1,Sdc2,Ccl12,Ezr,Cyfip1,Ust,Kdr,Vrk2,Rac3,Stat1,Ptk2,Sema4c,Sema4a,Lpar1,Rhou,Sema3c |
| 2.810e-02 | -3.57 | GO_CELLULAR_LIPID_METABOLIC_PROCESS | MSigDB lists | GO_CELLULAR_LIPID_METABOLIC_PROCESS | 834 | 82 | 15632 | 1249 |
Lipg,Ch25h,Cd74,St3gal6,Sphk1,Pigv,Fabp3,Itgb8,Mecp2,Cers6,B3gnt5,Stat5a,Lipe,Ddhd1,Acsl5,Kitl,Inpp1,Plaur,Il1b,Ptges,St3gal1,Ptgs2,Phyh,Nsmaf,Pdgfb,Inpp5b,Gbgt1,Degs2,Plek,Hsd17b12,Cd86,Asah2,Pik3r6,Pdgfrb,Sdc4,Cd80,Gpc1,Lpcat2,Pgs1,Lrp8,St3gal3,Mapkapk2,Sgms2,Sdc1,Irs2,Ppm1l,Pikfyve,Pla2g4a,Edn1,Pdpn,Slc44a1,Tgs1,Sdc2,Cept1,Dhrs9,Pik3r5,Agrn,Syk,B4galt4,Idi1,Chd9,Agpat4,Prkar2b,Abcc1,Tlr9,Etnk1,Mtmr14,Hmgcs1,C3,Mppe1,Pik3cd,Gpd2,Acsl1,Fabp7,Pdss1,Plscr1,St3gal5,Smpdl3b,Pla2g7,Sirt1,Atm,Cav1 |
| 2.817e-02 | -3.57 | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN | 189 | 23 | 15632 | 1249 |
Slc7a8,Cd274,Htra1,Ube2e2,Stat4,Slamf9,Tmem229b,Ccl4,Acsl5,Pf4,Spryd7,Gypc,Srm,Nr4a1,Parp8,Trip10,Gbp4,Gbp9,1110038F14Rik,Nfkbiz,Nlrp3,Gclc,Tnfaip3 |
| 2.817e-02 | -3.57 | GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | MSigDB lists | GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | 189 | 23 | 15632 | 1249 |
Plekha2,Zeb1,Sema4a,Usp42,Lpar1,Dyrk2,Traf3ip2,Hmgcs1,Ap3m2,Hsd17b7,Slfn9,Itpr1,Bcl2l11,Hsph1,Gbp4,Slc15a3,Gbp9,Cish,Parp14,Slfn8,Zc3hav1,Notch1,Sdc4 |
| 2.817e-02 | -3.57 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP | 189 | 23 | 15632 | 1249 |
Acvrl1,Nqo1,Slc39a4,Bcl6,Traf2,Brwd3,Plekha5,Spsb1,Jarid2,Pde4b,Stat5a,Ppfibp2,Rgs3,Nr4a3,Kif3c,Adrb2,Papss2,Grina,Dnajb4,Cyth3,Trim13,Mcoln2,St3gal1 |
| 2.822e-02 | -3.57 | DnaJ_CXXCXGXG | pfam domains | PF00684 | 4 | 2 | 18711 | 1348 |
Dnaja2,Dnaja1 |
| 2.822e-02 | -3.57 | NOD | pfam domains | PF06816 | 4 | 2 | 18711 | 1348 |
Notch1,Notch2 |
| 2.822e-02 | -3.57 | FERM_F2 | pfam domains | PF18377 | 4 | 2 | 18711 | 1348 |
Jak2,Tyk2 |
| 2.822e-02 | -3.57 | THF_DHG_CYH_C | pfam domains | PF02882 | 4 | 2 | 18711 | 1348 |
Mthfd1l,Mthfd2 |
| 2.822e-02 | -3.57 | THF_DHG_CYH | pfam domains | PF00763 | 4 | 2 | 18711 | 1348 |
Mthfd1l,Mthfd2 |
| 2.822e-02 | -3.57 | NODP | pfam domains | PF07684 | 4 | 2 | 18711 | 1348 |
Notch1,Notch2 |
| 2.822e-02 | -3.57 | Reticulon | pfam domains | PF02453 | 4 | 2 | 18711 | 1348 |
Rtn2,Rtn1 |
| 2.822e-02 | -3.57 | Jak1_Phl | pfam domains | PF17887 | 4 | 2 | 18711 | 1348 |
Tyk2,Jak2 |
| 2.822e-02 | -3.57 | FERM_F1 | pfam domains | PF18379 | 4 | 2 | 18711 | 1348 |
Jak2,Tyk2 |
| 2.822e-02 | -3.57 | Metallothio | pfam domains | PF00131 | 4 | 2 | 18711 | 1348 |
Mt2,Mt1 |
| 2.822e-02 | -3.57 | DUF3808 | pfam domains | PF10300 | 4 | 2 | 18711 | 1348 |
Ttc39c,Ttc39b |
| 2.822e-02 | -3.57 | UBA_6 | pfam domains | PF18039 | 4 | 2 | 18711 | 1348 |
Zc3h12c,Zc3h12a |
| 2.822e-02 | -3.57 | RHIM | pfam domains | PF12721 | 4 | 2 | 18711 | 1348 |
Ripk3,Zbp1 |
| 2.824e-02 | -3.57 | proteasome complex | cellular component | GO:0000502 | 64 | 9 | 20747 | 1409 |
Psmb6,Psmb8,Psma6,Usp25,Psme1,Dnajb2,Psmb9,Psmb10,Psmd10 |
| 2.830e-02 | -3.56 | negative regulation of calcium ion transport | biological process | GO:0051926 | 64 | 9 | 20694 | 1406 |
Icam1,Prkce,Gem,Ptgs2,Ahr,Gpr35,Tlr9,Slc30a1,Cacnb3 |
| 2.830e-02 | -3.56 | positive regulation of actin filament bundle assembly | biological process | GO:0032233 | 64 | 9 | 20694 | 1406 |
Sdc4,Rgcc,Rhoc,Cx3cl1,Carmil1,Lpar1,Plek,Swap70,Evl |
| 2.830e-02 | -3.56 | regulation of myoblast differentiation | biological process | GO:0045661 | 64 | 9 | 20694 | 1406 |
Tnf,Tnfsf14,Ccl9,Notch1,Ccl8,Cxcl9,Cxcl10,Cxcl14,Il18 |
| 2.837e-02 | -3.56 | The role of GTSE1 in G2/M progression after G2 checkpoint | REACTOME pathways | R-MMU-8852276 | 58 | 10 | 8608 | 757 |
Psmb6,Psme2,Psma6,Psmd10,Psme1,Psme2b,Psmb8,Psmb9,Psmb10,Cdkn1a |
| 2.837e-02 | -3.56 | Asymmetric localization of PCP proteins | REACTOME pathways | R-MMU-4608870 | 58 | 10 | 8608 | 757 |
Psmb10,Psmb9,Psmb8,Psme2b,Fzd5,Psme1,Psmd10,Psma6,Psme2,Psmb6 |
| 2.838e-02 | -3.56 | GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_UP | 179 | 22 | 15632 | 1249 |
Ccdc88b,Hcls1,Mppe1,Cyth3,Rab20,Map3k8,Azi2,Serpinb9,Irf2,Fas,Nck1,Rtn1,Rnf139,Glipr2,Kremen1,Leng9,Isg20,Nfkbib,Ampd3,Arhgef3,Traf2,Tap2 |
| 2.838e-02 | -3.56 | GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_DN | MSigDB lists | GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_DN | 179 | 22 | 15632 | 1249 |
Cd274,Cacybp,Ifi205,Mndal,Ifi209,Ifi213,Cst7,Ifi203,Ifi211,Tgs1,Slc39a4,Ifi208,Plagl1,Trib1,Ifi204,Nsmaf,Ifi214,Rnf139,Ifi207,Tcea1,Clec4e,Inpp1 |
| 2.838e-02 | -3.56 | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDC_DN | 179 | 22 | 15632 | 1249 |
Socs1,Slco3a1,Hck,Cx3cr1,Ctu1,Ppp1r14b,Rai14,Mtdh,Traf3ip2,Kcna3,Tlr2,Kif3c,Thbs1,Stard7,Ptges,Hsd17b7,Eif4g2,Lcp2,Myo1b,Heatr6,Pstpip2,Egln3 |
| 2.838e-02 | -3.56 | GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_UP | MSigDB lists | GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_UP | 179 | 22 | 15632 | 1249 |
Mmp14,Rnf24,Cnn3,Dusp4,Phactr4,Met,Ifrd1,Rgl1,Cd40,Rhof,Psmb9,Cd86,Gcnt2,Herc3,Sh3bgrl2,Dusp14,Pmepa1,Kif5c,Ube2e1,Aim2,Fgr,Arl4a |
| 2.838e-02 | -3.56 | GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_DN | MSigDB lists | GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_DN | 179 | 22 | 15632 | 1249 |
Malt1,Rnd1,Papss2,Kif9,Rbms2,Pilrb2,Cd80,Spic,Ccr3,Mdn1,Max,Tgfbi,Mefv,Pilrb1,Gca,Adam19,Tnfaip2,Clec4n,Procr,Csf3,Pla2g7,Jag1 |
| 2.841e-02 | -3.56 | protein phosphorylated amino acid binding | molecular function | GO:0045309 | 53 | 8 | 20217 | 1400 |
Crkl,Syk,Samsn1,Socs3,Fgr,Acp2,Stap1,Hck |
| 2.842e-02 | -3.56 | ErbB signaling pathway | WikiPathways | WP1261 | 46 | 10 | 4813 | 540 |
Nck1,Stat5a,Ptk2,Jun,Src,Myc,Pik3r5,Cdkn1a,Akt3,Map2k1 |
| 2.844e-02 | -3.56 | CDK-mediated phosphorylation and removal of Cdc6 | REACTOME pathways | R-MMU-69017 | 50 | 9 | 8608 | 757 |
Psmb9,Psmb8,Psmb10,Psme2,Psmb6,Psma6,Psme1,Psmd10,Psme2b |
| 2.844e-02 | -3.56 | REACTOME_SIGNALING_BY_NOTCH | MSigDB lists | REACTOME_SIGNALING_BY_NOTCH | 91 | 13 | 15632 | 1249 |
Myc,Notch2,Tle3,Ccnd1,Jag1,Hdac1,Dtx2,St3gal3,Jun,St3gal6,Hif1a,Mov10,Kat2b |
| 2.844e-02 | -3.56 | GO_INTEGRIN_BINDING | MSigDB lists | GO_INTEGRIN_BINDING | 91 | 13 | 15632 | 1249 |
Tgfbi,Icam1,Lyn,Cx3cl1,Itga5,Vcam1,Kdr,Thbs1,Ptpn2,Src,Syk,S1pr2,Mmp14 |
| 2.846e-02 | -3.56 | GO_SEQUENCE_SPECIFIC_DNA_BINDING | MSigDB lists | GO_SEQUENCE_SPECIFIC_DNA_BINDING | 880 | 86 | 15632 | 1249 |
Ifi205,Ifi213,Cebpd,Nr3c1,Egr2,Hif1a,Irf2,Mxd1,Mcm10,Hhex,Hlx,Notch1,Relb,Smg7,Tal2,Klf2,Junb,Jarid2,Maff,Ifi208,Kdm6b,Nfxl1,Snapc1,Fos,Jun,Hivep2,Nlrc5,Irf4,Myc,Plagl1,Etv3,Nlrp3,Atf3,Egr1,Hinfp,Hivep3,Sirt1,Stat4,Ifi203,Irf1,Mafg,Stat1,Actb,Tcf4,Bcl6,Ifi209,Mafk,Mecp2,Hdac1,Aebp2,Stat3,Batf2,Zfp281,Prdm1,Csrnp1,Etv5,Plagl2,Batf,Pbx1,Irf7,Fosb,Nr4a3,Arid5b,Nfkb2,Spic,Hmga1,Ets2,Nr4a1,Kat2b,Nr1h3,Ifi214,Foxp4,Ifi207,Rel,Lmo4,Mndal,Jdp2,Nfkb1,Etv6,Pou2f2,Ifi211,Ifi204,Max,H3f3b,Lhx2,Nfil3 |
| 2.847e-02 | -3.56 | GSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_DN | MSigDB lists | GSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_DN | 149 | 19 | 15632 | 1249 |
Txn1,Slc31a2,Abtb2,Sqstm1,Cd274,Ppm1k,Isg20,Peli1,Il18rap,Xkr8,Ebi3,Parp10,Pml,Rtp4,Ifih1,Zbp1,Slamf7,Ppfibp2,H3f3b |
| 2.851e-02 | -3.56 | GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_DN | MSigDB lists | GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_DN | 169 | 21 | 15632 | 1249 |
Znrf1,Il1rn,Lrrc25,Esd,Rhoc,Ptger4,Slc39a13,Cd180,Zfp281,Il2rg,Arl4a,Zeb1,Dennd1b,Tlk2,Nod2,S1pr2,Ltbp2,Slc16a3,Abcc5,Plod3,Tnfsf14 |
| 2.851e-02 | -3.56 | GSE3982_NEUTROPHIL_VS_TH1_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH1_UP | 169 | 21 | 15632 | 1249 |
Sema4a,P2ry14,Mmp25,Cx3cl1,Mppe1,Tlr6,Mxd1,Fam53c,Hlx,Slc28a2,Sec24b,Tle3,Apaf1,Sla,Plau,Pfkfb3,Sipa1l1,Serp1,Dock4,Ltbp2,Ifit2 |
| 2.851e-02 | -3.56 | IL21_UP.V1_UP | MSigDB lists | IL21_UP.V1_UP | 169 | 21 | 15632 | 1249 |
Slc7a5,Egr2,Rsad2,Il18rap,Mafk,Pla2g7,Fosb,Nos2,Bcl6,Slc28a2,Pim2,Zc3h12a,Lif,Tlr6,Aim2,Tlr3,Gpr85,Mmp25,Nr1h3,P2ry14,Pim1 |
| 2.851e-02 | -3.56 | MTOR_UP.V1_DN | MSigDB lists | MTOR_UP.V1_DN | 169 | 21 | 15632 | 1249 |
Klf2,Col11a2,Dusp1,Gramd1a,Pde4b,Plekha5,C1ra,Icosl,Htra1,Slc44a1,Myc,Phip,Slc39a13,Irs2,Max,H2-Ab1,Ptger4,Dtx2,Olfml3,Nfil3,Nfxl1 |
| 2.851e-02 | -3.56 | GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_DN | MSigDB lists | GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_DN | 169 | 21 | 15632 | 1249 |
Nr1h3,Trib1,Cdkn2d,Ier2,Nfil3,Angpt1,Gfi1,Tnfrsf14,Cd38,Gcnt2,P2ry2,Rbbp8,Gna15,Rgs14,Sp140,Rsad2,Spint2,Mdm2,Tbc1d1,Ext1,Ccr3 |
| 2.851e-02 | -3.56 | catalytic complex | cellular component | GO:1902494 | 1316 | 107 | 20747 | 1409 |
Gnb4,Crbn,Ankib1,Jarid2,Ccnj,Gclc,P4ha1,Ppp2r2a,Rnf19b,Med21,Cdkn1a,Ppp2r5a,Socs7,Gpd2,Traf2,Gna15,Pik3r5,Ppp2r1b,Hdac1,Pcgf5,Psmb8,Ppp4r2,Psmb10,Cish,Ccng2,Psmd10,Polr2g,Ube2e1,Smc5,Naa25,Ube2l6,Cacybp,Acvrl1,Dcun1d3,Rnf14,Usp25,Gclm,Dnajb2,Max,Taf4b,Socs1,Itpr1,Aebp2,Zswim4,Psme1,Sinhcaf,Cdk5r1,Kdm4a,Ppp1r15a,Cop1,Ccne1,Magohb,Socs3,Yju2,Rnf31,Zfp36,Gng11,Pnpt1,Tcea1,Pfkl,Kdm5b,Dr1,Pik3r6,Bcor,Sirt1,Cflar,Klhl25,P4ha2,Carhsp1,Psmb6,Trim21,Dync1i2,Actb,Casp8,Psmb9,Kdm6b,Dync1h1,Nck1,Dyrk2,Nox1,Gng12,Pdss1,Cdkn2d,Keap1,Pigv,Psma6,Igf1r,Ago3,Acvr1b,Eno1,Ep400,Ppp1r15b,Pik3cd,Kat2b,Gng4,Fbxo4,Rnf19a,Ccnd2,Ppp2r3a,Armc8,Eno2,Acvr1,Sap30,Ikbkg,Znfx1,Ccnd1,Spsb1 |
| 2.855e-02 | -3.56 | GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_DN | MSigDB lists | GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_DN | 159 | 20 | 15632 | 1249 |
Pdgfc,Mul1,Gpr141,Cd74,Cyth3,Odc1,Uba7,Stk40,Usp12,Treml2,Rbpms,Rffl,H2-Aa,Pdpn,Htra1,Gpr132,Ppp1r15b,Brd2,Psd4,H2-Eb1 |
| 2.855e-02 | -3.56 | GSE22342_CD11C_HIGH_VS_LOW_DECIDUAL_MACROPHAGES_UP | MSigDB lists | GSE22342_CD11C_HIGH_VS_LOW_DECIDUAL_MACROPHAGES_UP | 159 | 20 | 15632 | 1249 |
Plek,Ptch1,Itgal,Bbx,Dbnl,Ikzf1,Dcp1a,Mllt6,St3gal3,Endod1,Spata5l1,Prnp,Phip,Clec5a,Chd9,Sec24b,Vcpip1,Nfil3,Zfp319,Apaf1 |
| 2.857e-02 | -3.56 | NACHT | pfam domains | PF05729 | 33 | 6 | 18711 | 1348 |
Nlrp3,Nod1,Ciita,Nlrc5,Nod2,Nlrc4 |
| 2.858e-02 | -3.56 | regulation of cofactor metabolic process | biological process | GO:0051193 | 26 | 5 | 20694 | 1406 |
Slc7a11,Ptger4,Hp,Stat3,Pdk3 |
| 2.858e-02 | -3.56 | regulation of osteoblast proliferation | biological process | GO:0033688 | 26 | 5 | 20694 | 1406 |
Igf1r,Eif2ak2,Bmp2,Ahr,Itgav |
| 2.858e-02 | -3.56 | negative regulation of T cell apoptotic process | biological process | GO:0070233 | 26 | 5 | 20694 | 1406 |
Ccl5,Serpinb9,Arg2,Hif1a,Tnfsf4 |
| 2.858e-02 | -3.56 | embryonic hemopoiesis | biological process | GO:0035162 | 26 | 5 | 20694 | 1406 |
Kitl,Hif1a,Kdr,Pbx1,Ahr |
| 2.858e-02 | -3.56 | cell adhesion mediated by integrin | biological process | GO:0033627 | 26 | 5 | 20694 | 1406 |
Itga5,Icam1,Itgav,Itgb8,Itga4 |
| 2.858e-02 | -3.56 | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902175 | 26 | 5 | 20694 | 1406 |
Hsph1,Sod2,Nox1,Hif1a,Sirt1 |
| 2.858e-02 | -3.56 | negative regulation of biomineral tissue development | biological process | GO:0070168 | 26 | 5 | 20694 | 1406 |
Srgn,Bcor,Notch1,Hif1a,Ccr1 |
| 2.864e-02 | -3.55 | sterol homeostasis | biological process | GO:0055092 | 85 | 11 | 20694 | 1406 |
Ttc39b,Lipg,Il18,Sirt1,Ehd1,Cav1,Fabp3,Nr1h3,Med13,Sec24a,Ldlr |
| 2.875e-02 | -3.55 | protein self-association | molecular function | GO:0043621 | 63 | 9 | 20217 | 1400 |
Tnfaip3,Tcf4,Malt1,Rsad2,Myd88,Slc2a1,Gpsm2,Ccl5,Ctsc |
| 2.882e-02 | -3.55 | regulation of microtubule-based process | biological process | GO:0032886 | 234 | 24 | 20694 | 1406 |
Hap1,Hspa1b,Met,Hsph1,Plk2,Mid1,Trim36,Cenpj,Hspa1a,Tpx2,Mecp2,Dst,Chmp4b,Agrn,Phldb1,Gpsm2,Mark2,Gda,Parp3,Cdk5r1,Kat2b,Cav1,Tmem67,Dync1h1 |
| 2.883e-02 | -3.55 | GO_CATABOLIC_PROCESS | MSigDB lists | GO_CATABOLIC_PROCESS | 1622 | 150 | 15632 | 1249 |
Psme1,Ube2e1,Magohb,Pml,Stat2,Isg15,Sphk1,Bfar,Smg7,Lipe,Psmb9,Klhl25,Eno1,Birc2,Casp3,Fut8,Pnp2,Pde1b,Rffl,Mdm2,Psma6,Rnf19b,Smox,Usp31,Herc6,Zc3h12a,Uchl1,Ldha,Zhx2,Rnaset2a,Cnp,Ppm1k,Ube2l6,Oas2,Uba7,Hk2,Pttg1,Trim13,Xrn1,Pfkfb3,Herc3,Prdx1,Pde3b,Fbxo4,Pnpt1,Mark2,Chmp4b,Tnks1bp1,Samhd1,Agrn,Tet2,Psmd10,Il4i1,Slc44a1,Sdc2,Itpkc,Acsl1,Gpd2,Tmem67,Trem1,Pfkl,Rnaset2b,Esd,Psmb8,Eno2,Ankib1,Lnpep,Ubr4,Rims3,Ampd3,Rnf19a,Sirt1,Smpdl3b,Pla2g7,Dcp1a,Leng9,Rnf139,Usp18,Kmo,Upp1,Fabp3,Psmb10,Rnf34,Lipg,Gda,Tnfaip3,Ddhd1,Traf2,Mgat1,Sat1,Rnf24,Prdx5,Hmox1,Psmb6,Phyh,Usp42,Inpp1,Keap1,Ppp2r2a,Pgk1,Fcgr4,Pde4b,Col11a2,Map2k1,Mmp13,Usp35,Pde7b,Tpi1,Col18a1,Usp25,Sdc1,Dcp2,Pgm1,Aldh1b1,Znrf3,Sdc4,Col4a2,Gpc1,Hk3,Enpp4,Dnase1l3,Crbn,Sqstm1,Pla2g4a,Ctsc,Bnip3,Mmp14,Vcan,Cnot4,Pde5a,Scarf1,Mmp9,Rnf145,Znrf1,Polr2g,Ldlr,Dnajb2,Atm,Rnf14,Hk1,Hdc,Casp8,Nos2,Plod2,Fabp7,Isg20,Slc9a1,Zfp36,Psme2,Usp12 |
| 2.892e-02 | -3.54 | GO_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | MSigDB lists | GO_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | 38 | 7 | 15632 | 1249 |
Mmp9,Bcl2l11,Psmd10,Bnip3,Tnfsf10,Plaur,Fam162a |
| 2.892e-02 | -3.54 | chr2q24 | MSigDB lists | chr2q24 | 38 | 7 | 15632 | 1249 |
Ifih1,Cd302,Gpd2,Tank,Rbms1,Ly75,Slc25a12 |
| 2.892e-02 | -3.54 | chr6q23 | MSigDB lists | chr6q23 | 38 | 7 | 15632 | 1249 |
Ust,Reps1,Tnfaip3,Pde7b,Eya4,Hivep2,Cited2 |
| 2.892e-02 | -3.54 | GO_FATTY_ACID_DERIVATIVE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_FATTY_ACID_DERIVATIVE_BIOSYNTHETIC_PROCESS | 38 | 7 | 15632 | 1249 |
Syk,Edn1,Pla2g4a,Ptges,Sphk1,Ptgs2,Cd74 |
| 2.892e-02 | -3.54 | MILI_PSEUDOPODIA | MSigDB lists | MILI_PSEUDOPODIA | 38 | 7 | 15632 | 1249 |
Palld,Ccnd2,Coa5,Inpp1,Pkp4,Xaf1,Vcpip1 |
| 2.893e-02 | -3.54 | regulation of synaptic transmission, GABAergic | biological process | GO:0032228 | 35 | 6 | 20694 | 1406 |
Stxbp1,Prkce,Adora2a,Hap1,Nlgn2,Plcl2 |
| 2.893e-02 | -3.54 | acylglycerol homeostasis | biological process | GO:0055090 | 35 | 6 | 20694 | 1406 |
Lipg,Il18,Sirt1,Nr1h3,Map2k1,Med13 |
| 2.893e-02 | -3.54 | brown fat cell differentiation | biological process | GO:0050873 | 35 | 6 | 20694 | 1406 |
Plac8,Ero1l,Bnip3,Adrb2,Arl4a,Ptgs2 |
| 2.893e-02 | -3.54 | triglyceride homeostasis | biological process | GO:0070328 | 35 | 6 | 20694 | 1406 |
Map2k1,Nr1h3,Med13,Lipg,Il18,Sirt1 |
| 2.900e-02 | -3.54 | REACTOME_HS_GAG_BIOSYNTHESIS | MSigDB lists | REACTOME_HS_GAG_BIOSYNTHESIS | 30 | 6 | 15632 | 1249 |
Agrn,Gpc1,Sdc4,Ext1,Sdc1,Sdc2 |
| 2.900e-02 | -3.54 | HUNSBERGER_EXERCISE_REGULATED_GENES | MSigDB lists | HUNSBERGER_EXERCISE_REGULATED_GENES | 30 | 6 | 15632 | 1249 |
Egr2,Csf3,Dusp6,Egr1,Ldha,Odc1 |
| 2.900e-02 | -3.54 | WENDT_COHESIN_TARGETS_UP | MSigDB lists | WENDT_COHESIN_TARGETS_UP | 30 | 6 | 15632 | 1249 |
Tlk2,Plekha5,Usp25,Rnd3,Ptk2,Fut8 |
| 2.900e-02 | -3.54 | GO_SUPEROXIDE_METABOLIC_PROCESS | MSigDB lists | GO_SUPEROXIDE_METABOLIC_PROCESS | 30 | 6 | 15632 | 1249 |
Nqo1,Edn1,Prdx1,Nos2,Nox1,Sod2 |
| 2.900e-02 | -3.54 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | MSigDB lists | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | 30 | 6 | 15632 | 1249 |
Pik3r6,Lyn,Lcp2,Pik3r5,Syk,Akt3 |
| 2.900e-02 | -3.54 | GO_RESPONSE_TO_ISOQUINOLINE_ALKALOID | MSigDB lists | GO_RESPONSE_TO_ISOQUINOLINE_ALKALOID | 30 | 6 | 15632 | 1249 |
Prkce,Mdm2,Ppp2r2a,Il1b,Ccl5,Fosb |
| 2.900e-02 | -3.54 | VANTVEER_BREAST_CANCER_BRCA1_UP | MSigDB lists | VANTVEER_BREAST_CANCER_BRCA1_UP | 30 | 6 | 15632 | 1249 |
Vrk2,Wdr43,Dennd1b,Pim2,Ccl12,Myc |
| 2.900e-02 | -3.54 | GO_POSITIVE_REGULATION_OF_VASODILATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_VASODILATION | 30 | 6 | 15632 | 1249 |
Hmox1,Gja1,Ptafr,Nos2,Adrb2,Kat2b |
| 2.900e-02 | -3.54 | REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES | MSigDB lists | REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES | 30 | 6 | 15632 | 1249 |
Fos,Jun,Dusp4,Dusp6,Mapkapk2,Ppp2r1b |
| 2.900e-02 | -3.54 | REACTOME_GLUCONEOGENESIS | MSigDB lists | REACTOME_GLUCONEOGENESIS | 30 | 6 | 15632 | 1249 |
Eno1,Tpi1,Eno2,Pgk1,Pcx,Slc25a12 |
| 2.900e-02 | -3.54 | GO_POSITIVE_CHEMOTAXIS | MSigDB lists | GO_POSITIVE_CHEMOTAXIS | 30 | 6 | 15632 | 1249 |
Vegfc,Angpt1,Met,Pdgfb,Ptprj,Ccl5 |
| 2.900e-02 | -3.54 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_OLD | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_GAMMA_IN_OLD | 30 | 6 | 15632 | 1249 |
Trp53i11,Sgcb,H2-Aa,Itgb8,Cept1,Glrx |
| 2.900e-02 | -3.54 | DASU_IL6_SIGNALING_SCAR_UP | MSigDB lists | DASU_IL6_SIGNALING_SCAR_UP | 30 | 6 | 15632 | 1249 |
Tnc,Zfp36,Larp1,Agrn,Cdc42ep4,Tpx2 |
| 2.900e-02 | -3.54 | GO_NEGATIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS | 30 | 6 | 15632 | 1249 |
Gja1,Pml,Dusp1,Dach1,Src,Acvrl1 |
| 2.900e-02 | -3.54 | actin binding | molecular function | GO:0003779 | 424 | 40 | 20217 | 1400 |
Marcksl1,Cdk5r1,Pstpip2,Diaph2,Rcsd1,Daam1,Syne2,Marcks,Tmsb10,Ptk2,Palld,Cyfip1,Sipa1l1,Nos2,Pdlim7,Evl,Spire1,Flnb,Tmod3,Triobp,Mefv,Fmnl2,Myo1b,Myo10,Dbnl,Phactr4,Dst,Cnn2,Fscn1,Hcls1,Prkce,Vasp,Antxr1,Tpm4,Nod2,Micall2,Tagln,Whamm,Cnn3,Ezr |
| 2.900e-02 | -3.54 | MULLIGHAN_MLL_SIGNATURE_1_DN | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_1_DN | 210 | 25 | 15632 | 1249 |
Cav1,Sipa1l1,Slc13a3,Ifit1bl2,Hsd17b12,Stat4,Wdr59,Egr3,Ptgir,Cd200,Abcc4,Fscn1,Cxcl1,Stat5a,Ifit1bl1,Src,Agrn,Itgav,Rbpms,Abcb1a,D1Ertd622e,Ifi44,Stap1,Ube2e1,Asap3 |
| 2.906e-02 | -3.54 | TYR_PHOSPHATASE_dom | interpro domains | IPR000387 | 81 | 11 | 19984 | 1430 |
Ptpn2,Dusp8,Dusp14,Dusp2,Dusp1,Dusp6,Dusp28,Dusp4,Dusp5,Ptprj,Dusp16 |
| 2.907e-02 | -3.54 | Phosphorylation of CD3 and TCR zeta chains | REACTOME pathways | R-MMU-202427 | 14 | 4 | 8608 | 757 |
H2-Eb1,H2-Aa,H2-Ab1,Ptprj |
| 2.909e-02 | -3.54 | - | gene3d domains | 1.10.1300.10 | 21 | 5 | 8819 | 755 |
Pde4b,Pde3b,Pde7b,Pde5a,Pde1b |
| 2.912e-02 | -3.54 | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | MSigDB lists | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | 55 | 9 | 15632 | 1249 |
Il1b,Sirt1,Ncoa5,Cish,Socs1,Ptpn2,Pid1,Socs3,Src |
| 2.912e-02 | -3.54 | CCACACA_MIR147 | MSigDB lists | CCACACA_MIR147 | 55 | 9 | 15632 | 1249 |
Slc44a1,Ppp2r1b,Nr3c1,Triobp,Rgs3,Mecp2,Klf7,Bcor,Tiparp |
| 2.912e-02 | -3.54 | WESTON_VEGFA_TARGETS_6HR | MSigDB lists | WESTON_VEGFA_TARGETS_6HR | 55 | 9 | 15632 | 1249 |
Ccl12,Gem,Adora2b,Tnfsf10,Sdc4,Vcam1,Sat1,Htr2b,Vcan |
| 2.912e-02 | -3.54 | MODULE_525 | MSigDB lists | MODULE_525 | 55 | 9 | 15632 | 1249 |
Irs2,Tagap,Nfkbid,G3bp2,Cd164,Syne2,Cd69,Orai2,Peli1 |
| 2.912e-02 | -3.54 | REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C | MSigDB lists | REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C | 55 | 9 | 15632 | 1249 |
Psme2,Psma6,Ube2e1,Psmb8,Psme1,Psmb6,Psmb9,Psmd10,Psmb10 |
| 2.912e-02 | -3.54 | ISSAEVA_MLL2_TARGETS | MSigDB lists | ISSAEVA_MLL2_TARGETS | 55 | 9 | 15632 | 1249 |
Pcdh7,Plau,Oas1a,Axl,Oas1g,Flrt2,Il18,Slco3a1,Fabp3 |
| 2.912e-02 | -3.54 | REACTOME_REGULATION_OF_APOPTOSIS | MSigDB lists | REACTOME_REGULATION_OF_APOPTOSIS | 55 | 9 | 15632 | 1249 |
Psmb8,Psme1,Psmb6,Psmd10,Psmb9,Psmb10,Casp3,Psme2,Psma6 |
| 2.915e-02 | -3.54 | GO_ORGAN_REGENERATION | MSigDB lists | GO_ORGAN_REGENERATION | 82 | 12 | 15632 | 1249 |
Cdkn1a,Notch1,Lif,Socs3,Fas,Adrb2,Nr4a3,Socs1,Ccnd1,Ccl12,Ccne1,Cav1 |
| 2.915e-02 | -3.54 | KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION | MSigDB lists | KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION | 82 | 12 | 15632 | 1249 |
Ccnd1,Cept1,Nrp2,Dnaja1,Tcf4,N4bp1,Rbl1,Vcam1,Gclc,Pbx1,Lox,Ptger4 |
| 2.915e-02 | -3.54 | ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | MSigDB lists | ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | 82 | 12 | 15632 | 1249 |
Fos,Cav1,Cited2,Csrp1,Ccnd1,Ppfia3,Myc,Egr2,Ak4,Rhoh,Myo10,Me1 |
| 2.919e-02 | -3.53 | positive regulation of cell cycle phase transition | biological process | GO:1901989 | 96 | 12 | 20694 | 1406 |
Ccnd1,Pbx1,Rgcc,Tmod3,Ccnd2,Cenpe,Mecp2,Hspa2,Ube2e2,Ankrd17,Ccne1,Mdm2 |
| 2.919e-02 | -3.53 | regulation of glial cell differentiation | biological process | GO:0045685 | 96 | 12 | 20694 | 1406 |
Kdm4a,Lif,Mecp2,Clcf1,Tlr2,Tnfrsf1b,Hdac1,Hmga2,Notch1,Bmp2,Il1b,Ldlr |
| 2.924e-02 | -3.53 | cell morphogenesis involved in differentiation | biological process | GO:0000904 | 573 | 51 | 20694 | 1406 |
Tsku,Ext1,Ntng2,Triobp,Igf1r,Antxr1,Clic4,Rab10,Lrp8,Flrt2,Frmd6,Uchl1,Col18a1,Actb,Plod3,Itga4,Sec24b,Agrn,Clic5,Ptk2,Stxbp1,Kif5c,Egr2,Met,Evl,Sdc2,Cnp,Spint2,Ptch1,Itgav,Flrt3,Flnb,Nr4a3,Cdk5r1,Klf7,Palld,Notch1,Axl,Rilpl1,Dst,Scn1b,Cyfip1,Lrp4,Vasp,Src,Nrp2,Sema3c,Lhx2,Dock10,Sema4a,Micall2 |
| 2.930e-02 | -3.53 | Cyclin_C-dom | interpro domains | IPR004367 | 17 | 4 | 19984 | 1430 |
Ccnd2,Ccne1,Ccnd1,Ccnj |
| 2.939e-02 | -3.53 | CACCAGC_MIR138 | MSigDB lists | CACCAGC_MIR138 | 200 | 24 | 15632 | 1249 |
Rhoc,St3gal3,Mllt6,Clmp,Ptpn2,Tiparp,Arhgef3,Osbpl3,H3f3b,Igf2bp2,Ptk2,Sema4c,Cpeb4,Nr4a3,Frmd4a,Mafg,Scn1b,Dcp1a,Pde7b,Sirt1,Ccne1,Mier3,Rims3,Mov10 |
| 2.948e-02 | -3.52 | BCL2FAMILY | prints domains | PR01862 | 11 | 3 | 5821 | 374 |
Bcl2a1a,Bcl2a1b,Bcl2a1d |
| 2.949e-02 | -3.52 | SMTTTTGT_UNKNOWN | MSigDB lists | SMTTTTGT_UNKNOWN | 358 | 39 | 15632 | 1249 |
Tnfsf10,Gpr85,Nr4a3,Crkl,Sema4c,Cpeb4,Cnn3,Rab10,Pdgfb,Med13,Daam1,Fzd5,Lmo4,Ccnj,Arid4a,Jarid2,Eif4g2,P4ha1,Dusp6,Klf7,Myo10,Rras2,Tab2,Cd180,Mapkapk2,Ogfrl1,Gadd45g,Dusp4,Mid1,Itgb8,Mmp14,Mtus1,Itpr1,Bcl6,Tcf4,Ets2,Cited2,Ehd1,Flrt3 |
| 2.950e-02 | -3.52 | ATF4_Q2 | MSigDB lists | ATF4_Q2 | 231 | 27 | 15632 | 1249 |
Trib1,Nr4a3,Itpkc,Zhx2,Ppp1r15a,Gem,Lmo4,Fosb,Nfkbid,Jag1,Noc4l,Tab2,Arg2,Cdk5r1,Hhex,Relb,Ahr,Kif9,Fos,Rbbp8,Zmynd15,Eno1,Dusp1,Cenpe,Psd,S1pr2,Kcnj2 |
| 2.953e-02 | -3.52 | positive regulation of intracellular transport | biological process | GO:0032388 | 187 | 20 | 20694 | 1406 |
Mdm2,Cacnb3,Prnp,Zc3h12a,Ccl2,Adora2b,Ezr,Rab21,Hcls1,Uaca,Fgr,Mecp2,Syk,Stxbp1,Dync1h1,Ehd1,Il4ra,Plk3,Ptgs2,Cdk5r1 |
| 2.953e-02 | -3.52 | regulation of protein localization to membrane | biological process | GO:1905475 | 187 | 20 | 20694 | 1406 |
Actb,Prnp,Ccl2,Cacnb3,Map2k1,Pid1,Mmp14,Ezr,Pmaip1,Rhoq,Nlgn2,Lztfl1,Sqstm1,Crkl,Tnf,Gpc1,Cdk5r1,Lrp4,Ppp2r5a,Slc7a11 |
| 2.959e-02 | -3.52 | PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP | MSigDB lists | PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP | 73 | 11 | 15632 | 1249 |
Slc7a8,Eno1,Ets2,Gclm,Sap30,Xkr8,Lyn,Tpx2,Stip1,Atp2b4,Pgk1 |
| 2.959e-02 | -3.52 | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP | MSigDB lists | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP | 73 | 11 | 15632 | 1249 |
Arf4,Fut8,Irf4,Fgl2,Il15ra,Cd38,Ell2,Spn,Cited2,Cav1,Trib1 |
| 2.964e-02 | -3.52 | REACTOME_ORC1_REMOVAL_FROM_CHROMATIN | MSigDB lists | REACTOME_ORC1_REMOVAL_FROM_CHROMATIN | 64 | 10 | 15632 | 1249 |
Psme2,Psma6,Cdkn1a,Psmb8,Psme1,Psmb6,Psmd10,Psmb9,Psmb10,Mcm6 |
| 2.964e-02 | -3.52 | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS | MSigDB lists | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS | 64 | 10 | 15632 | 1249 |
Psme2,Psma6,Psmb8,Psme1,Ube2e1,Psmb6,Psmb9,Psmd10,Pttg1,Psmb10 |
| 2.965e-02 | -3.52 | GOUYER_TATI_TARGETS_UP | MSigDB lists | GOUYER_TATI_TARGETS_UP | 9 | 3 | 15632 | 1249 |
Lcn2,Ccl12,Tnf |
| 2.965e-02 | -3.52 | RAFFEL_VEGFA_TARGETS_UP | MSigDB lists | RAFFEL_VEGFA_TARGETS_UP | 9 | 3 | 15632 | 1249 |
Hif1a,Cited2,Pbx1 |
| 2.965e-02 | -3.52 | ITO_PTTG1_TARGETS_DN | MSigDB lists | ITO_PTTG1_TARGETS_DN | 9 | 3 | 15632 | 1249 |
Itga5,Fscn1,Pttg1 |
| 2.965e-02 | -3.52 | BIOCARTA_IL5_PATHWAY | MSigDB lists | BIOCARTA_IL5_PATHWAY | 9 | 3 | 15632 | 1249 |
Il1b,Ccr3,Il6 |
| 2.965e-02 | -3.52 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | MSigDB lists | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | 9 | 3 | 15632 | 1249 |
Myd88,Tlr9,Irf7 |
| 2.965e-02 | -3.52 | GO_NEGATIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | 9 | 3 | 15632 | 1249 |
Bcl6,Ifnb1,Hlx |
| 2.965e-02 | -3.52 | GO_NEGATIVE_REGULATION_OF_NECROTIC_CELL_DEATH | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NECROTIC_CELL_DEATH | 9 | 3 | 15632 | 1249 |
Birc3,Birc2,Cav1 |
| 2.965e-02 | -3.52 | AGARWAL_AKT_PATHWAY_TARGETS | MSigDB lists | AGARWAL_AKT_PATHWAY_TARGETS | 9 | 3 | 15632 | 1249 |
Vegfc,Ptgs2,Mmp9 |
| 2.965e-02 | -3.52 | XU_HGF_TARGETS_REPRESSED_BY_AKT1_UP | MSigDB lists | XU_HGF_TARGETS_REPRESSED_BY_AKT1_UP | 9 | 3 | 15632 | 1249 |
Sod2,Ccl12,Sat1 |
| 2.965e-02 | -3.52 | MODULE_454 | MSigDB lists | MODULE_454 | 9 | 3 | 15632 | 1249 |
Adora2b,Adora2a,Adrb2 |
| 2.965e-02 | -3.52 | ST_INTERFERON_GAMMA_PATHWAY | MSigDB lists | ST_INTERFERON_GAMMA_PATHWAY | 9 | 3 | 15632 | 1249 |
Jak2,Stat1,Cish |
| 2.965e-02 | -3.52 | WHITESIDE_CISPLATIN_RESISTANCE_UP | MSigDB lists | WHITESIDE_CISPLATIN_RESISTANCE_UP | 9 | 3 | 15632 | 1249 |
Gdf15,Ptges,Cdkn1a |
| 2.965e-02 | -3.52 | SCHMAHL_PDGF_SIGNALING | MSigDB lists | SCHMAHL_PDGF_SIGNALING | 9 | 3 | 15632 | 1249 |
Csrnp1,Tiparp,Arid5b |
| 2.965e-02 | -3.52 | OSAWA_TNF_TARGETS | MSigDB lists | OSAWA_TNF_TARGETS | 9 | 3 | 15632 | 1249 |
Tnfaip2,Cflar,Ier3 |
| 2.966e-02 | -3.52 | Regulation of DNA replication | REACTOME pathways | R-MMU-69304 | 75 | 12 | 8608 | 757 |
Psme1,Psmd10,Psme2b,Psme2,Psmb6,Psma6,Psmb10,Cdkn1a,Mcm10,Mcm6,Psmb9,Psmb8 |
| 2.966e-02 | -3.52 | F_BAR | prosite domains | PS51741 | 23 | 5 | 13278 | 1037 |
Fnbp1l,Fchsd2,Fcho2,Trip10,Pstpip2 |
| 2.972e-02 | -3.52 | GO_ORGANIC_ACID_BINDING | MSigDB lists | GO_ORGANIC_ACID_BINDING | 190 | 23 | 15632 | 1249 |
Gfpt1,Thbs1,Hmgcs1,Lpar1,Phyh,Fcho2,Egln3,Rasgrp1,S100a8,P4ha1,Nos2,Plod2,Gclc,Rars,Fabp3,Stard5,Sele,Pcx,Axl,P4ha2,Ass1,Agrn,Plod3 |
| 2.972e-02 | -3.52 | GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_UP | MSigDB lists | GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_UP | 190 | 23 | 15632 | 1249 |
Palld,Slco3a1,Ccl22,Sla,Sdc4,Pdgfc,Eno1,Cish,Irf4,Il18bp,Dyrk2,Shisa3,Mtmr14,Nfxl1,Ccl5,Slc7a8,Ttc9c,Pik3r6,Alas1,Piezo1,Pdgfb,Ext1,Spint2 |
| 2.972e-02 | -3.52 | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN | 190 | 23 | 15632 | 1249 |
Endod1,Casp7,Serpinb9,Slc43a3,Cdkn1a,Tnfrsf1b,Ccne1,Snx10,Gem,Irf8,Plscr1,Lrp8,Nupr1,H2-Q7,Prdm1,Slamf7,Sgcb,H2-Q4,Rhbdf2,H2-Q6,Cyfip1,Slc15a3,Rhoq |
| 2.972e-02 | -3.52 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_NKCELL_UP | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_NKCELL_UP | 190 | 23 | 15632 | 1249 |
Casp1,Plekha5,Pde4b,Cish,Dusp8,Ampd3,Slc44a1,Csf1,Dgka,Dcp1a,Kif5c,Rhoh,Ppa1,Kdm6b,Malt1,Larp1,Zfp281,Tab2,Tax1bp1,Sgcb,Zc3hav1,Ahr,Esd |
| 2.973e-02 | -3.52 | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | MSigDB lists | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | 101 | 14 | 15632 | 1249 |
Irf4,Stat3,Minpp1,Myc,Ampd3,Junb,Klf6,Stat5a,Samsn1,Lcp2,Slc48a1,Rhoc,Pim1,Arl4a |
| 2.973e-02 | -3.52 | VANTVEER_BREAST_CANCER_METASTASIS_DN | MSigDB lists | VANTVEER_BREAST_CANCER_METASTASIS_DN | 101 | 14 | 15632 | 1249 |
Dck,Mmp9,Mtdh,Mcm6,Gbe1,Col4a2,Pgk1,Flt1,Gpsm2,Asns,Cp,Trip13,Ext1,Bnip3 |
| 2.975e-02 | -3.51 | Kringle-like | interpro domains | IPR013806 | 25 | 5 | 19984 | 1430 |
Mmp9,Plau,Plat,Ly75,Kremen1 |
| 2.979e-02 | -3.51 | mouse chr8|8 B3.1 | chromosome location | mouse chr8|8 B3.1 | 20 | 4 | 24173 | 1464 |
Tma16,Ddx60,Palld,Mfap3l |
| 2.989e-02 | -3.51 | regulation of small GTPase mediated signal transduction | biological process | GO:0051056 | 259 | 26 | 20694 | 1406 |
Met,Src,Gpr35,Map4k4,Map2k1,Rasgrp1,Arhgef3,Spata13,Arhgap26,Abr,Kitl,Cyth3,Lpar1,Pdgfrb,Bcl6,Notch1,Prag1,Sipa1l1,Psd,Rap1gap2,Csf1,Gpr18,Rabgef1,Psd4,Notch2,Spry2 |
| 2.994e-02 | -3.51 | recycling endosome | cellular component | GO:0055037 | 141 | 16 | 20747 | 1409 |
Atp11b,Fchsd2,Ehd1,Tnf,Ldlr,Fcgr2b,Stx6,Cd274,Mcoln2,Slc31a1,Atp11a,Dennd6b,Rab10,Rap2c,Micall2,Slc31a2 |
| 2.995e-02 | -3.51 | Cyclin_C | pfam domains | PF02984 | 17 | 4 | 18711 | 1348 |
Ccne1,Ccnj,Ccnd2,Ccnd1 |
| 2.998e-02 | -3.51 | SM22_calponin | interpro domains | IPR003096 | 10 | 3 | 19984 | 1430 |
Tagln,Cnn3,Cnn2 |
| 2.998e-02 | -3.51 | MHC_II_a/b_N | interpro domains | IPR014745 | 10 | 3 | 19984 | 1430 |
H2-Ab1,H2-Eb1,H2-Aa |
| 2.999e-02 | -3.51 | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | 180 | 22 | 15632 | 1249 |
Rbbp8,Swap70,Aoah,Psd,Nfkbie,Minpp1,Mcm10,Psme1,Irf2,Tal2,Fbxo4,Traf5,Casp8,Lad1,Samsn1,Myo1b,Jarid2,Casp2,Trim21,Crkl,Epsti1,Asf1a |
| 2.999e-02 | -3.51 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP | 180 | 22 | 15632 | 1249 |
Acsl5,Hck,Pfkl,Cdkn2d,Mmp9,Ier2,Hhex,Pik3cd,Rcn1,Kat2b,Tgfbi,Egr2,Pla2g4a,Ikzf1,Kctd12,Casp2,Cebpd,Ddhd1,Parp8,Rgl1,Jun,Psmb9 |
| 2.999e-02 | -3.51 | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | MSigDB lists | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | 180 | 22 | 15632 | 1249 |
Sat1,Top3a,Treml2,Oas1a,Ifit1bl1,Ifit1bl2,Slc7a8,Rnf114,Abcc5,Hk1,Ifit3,Rgs14,Cd302,Osbpl3,Tnfsf10,Klf7,Pdgfc,Endod1,Oas1g,Cd180,Fam111a,Ifit3b |
| 2.999e-02 | -3.51 | GSE24574_NAIVE_VS_TCONV_CD4_TCELL_DN | MSigDB lists | GSE24574_NAIVE_VS_TCONV_CD4_TCELL_DN | 180 | 22 | 15632 | 1249 |
Rras2,Tnf,Srm,Homer1,Eno1,Ggct,Pnp2,Ccdc86,Psma6,Dusp5,Psmb6,Rcn1,Rcan1,Nsmaf,Cflar,Polr2g,Idi1,Ccl4,Wdr43,Txn1,Trip13,Il18rap |
| 2.999e-02 | -3.51 | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN | 180 | 22 | 15632 | 1249 |
Gna15,Gem,Tnfrsf1b,Itgav,Nod2,Slc39a14,B3gnt5,Irf4,Egr2,Ppp2r5a,Dusp2,Slc7a5,Tnip3,Pttg1,Ier3,Nr4a3,Prdm1,Slc31a1,Znrf1,Irak2,Inpp1,Gca |
| 2.999e-02 | -3.51 | GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP | MSigDB lists | GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP | 180 | 22 | 15632 | 1249 |
Ap3m2,Snn,Stard7,Gcnt2,Nod1,Fgr,Phip,Filip1l,Mxd1,Casp2,Rap1gap2,Tdrd7,Dock10,Treml2,Ikzf1,Abcb1a,Spic,Itpr1,Sbds,Lrp4,Dusp6,Mier3 |
| 2.999e-02 | -3.51 | GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_DN | MSigDB lists | GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_DN | 180 | 22 | 15632 | 1249 |
Hck,Fbrsl1,Kif9,Nr1h3,Trim12c,Ptgir,Itga4,Lrch3,Hap1,Dbnl,Irf4,Ccr3,Gpr18,Spic,Traf2,Ppm1k,Itpr1,Marco,Psip1,Nfkb1,Spn,Slc25a37 |
| 2.999e-02 | -3.51 | GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP | MSigDB lists | GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP | 180 | 22 | 15632 | 1249 |
Arl4a,Pigv,Ccnd2,Ddx58,Prnp,Usp18,Pml,Slfn5,Ifit1,Tspo,Fbrsl1,Oas3,Flrt3,Rsad2,Sdc2,Sele,Slfn8,Ifi35,Slfn9,Kdr,Zcchc2,Oas2 |
| 2.999e-02 | -3.51 | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN | 180 | 22 | 15632 | 1249 |
Gbp2,Trp53i11,Irf2,Ncoa5,Fgl2,Triobp,Irgm2,Arhgef3,Eif2ak2,Fam102b,Stat1,Smc5,Dennd2a,Rap1gap2,Kctd12,Inpp5b,Btg2,Trim21,Lgals9,Lad1,Rims3,Tshz1 |
| 2.999e-02 | -3.51 | HOLLMANN_APOPTOSIS_VIA_CD40_UP | MSigDB lists | HOLLMANN_APOPTOSIS_VIA_CD40_UP | 180 | 22 | 15632 | 1249 |
Ets2,Hsph1,Plekhf2,Ppp6r1,Hdac1,Gsr,Tbc1d1,Nr3c1,Stap1,Cd38,Sgcb,Cd86,Irf8,Lap3,Snx10,Map4k4,Timeless,Rnf19b,Endod1,Ppp2r2a,Tcea1,Adam19 |
| 2.999e-02 | -3.51 | GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP | MSigDB lists | GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP | 180 | 22 | 15632 | 1249 |
Tagap,Aff1,Rbl1,Cd83,Plagl1,Icam1,Cdk5r1,Ptprj,Tnfsf4,Dyrk2,Kif5c,Trim56,Dusp4,Parp12,Tlr1,Slc44a1,Itgal,Mgat1,4930523C07Rik,S100a8,Card6,Sesn3 |
| 2.999e-02 | -3.51 | GSE17721_4H_VS_24H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_4H_VS_24H_POLYIC_BMDC_DN | 180 | 22 | 15632 | 1249 |
Tnfrsf1b,Ampd3,Il12rb1,Mmd,Sh3bp4,Kctd12,Smc5,Acsl1,Sh3bgrl2,Cmklr1,Pfkl,Ptges,Gramd1a,Ctu1,Dbnl,Prdx5,Nfkbil1,Tulp3,Coa5,Pfkfb3,Zbp1,Gclc |
| 2.999e-02 | -3.51 | GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN | MSigDB lists | GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN | 180 | 22 | 15632 | 1249 |
Marcksl1,Itga4,Egr1,Cd74,Il18,Hcls1,Cdkn1a,Tnfaip3,Snn,Lrrc8c,Abtb2,Ezr,Cenpe,Syk,Rapgef5,Klf2,Lgals9,Gpsm2,Jun,Hspa1a,Carhsp1,Fam72a |
| 2.999e-02 | -3.51 | GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | MSigDB lists | GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | 180 | 22 | 15632 | 1249 |
Tifa,Eya4,Pla2g7,Mfap3l,Fam102b,Bambi,Slc29a3,Lacc1,Pkp4,Abcc4,Htr2b,Tlr3,Itgb8,Lrp4,Tspan3,Cd302,Pfkfb3,Rnf34,Rbl1,Kat2b,Nmral1,Nr1h3 |
| 3.001e-02 | -3.51 | modification-dependent macromolecule catabolic process | biological process | GO:0043632 | 484 | 44 | 20694 | 1406 |
Tnfaip3,Crbn,Usp18,Znrf1,Isg15,Trim13,Sirt1,Spsb1,Arel1,Mdm2,Ankib1,Psma6,Rnf14,Usp12,Usp25,Ubr4,Fbxo4,Peli1,Ube2l6,Tut7,Dnajb2,Uchl1,Birc2,Tmem67,Cnot4,Cop1,Rnf19b,Psmb10,Psmb6,Dtx3l,Pnpt1,Rffl,Usp42,Rnf34,Znrf3,Armc8,Uba7,Pml,Psmb8,Klhl25,Rnf19a,Arrdc4,Psmb9,Bfar |
| 3.010e-02 | -3.50 | PDIESTERASE1 | prints domains | PR00387 | 19 | 4 | 5821 | 374 |
Pde7b,Pde1b,Pde4b,Pde5a |
| 3.011e-02 | -3.50 | ear development | biological process | GO:0043583 | 235 | 24 | 20694 | 1406 |
Cebpd,Slc4a7,Rpgrip1l,Sec24b,Myc,Clic5,Zeb1,Notch1,Mapkapk2,Gfi1,Cxcl14,Tshz1,Triobp,Edn1,Nr4a3,Spry2,Bcl2l11,Bmp2,Eya4,Sdc4,Ttc39c,Jag1,Ifi204,Abr |
| 3.011e-02 | -3.50 | protein phosphatase type 2A complex | cellular component | GO:0000159 | 18 | 4 | 20747 | 1409 |
Ppp2r2a,Ppp2r3a,Ppp2r5a,Ppp2r1b |
| 3.015e-02 | -3.50 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway | biological process | GO:0039531 | 18 | 4 | 20694 | 1406 |
Ankrd17,Zc3hav1,Ddx60,Dhx58 |
| 3.015e-02 | -3.50 | negative regulation of cardiac muscle cell proliferation | biological process | GO:0060044 | 18 | 4 | 20694 | 1406 |
Jarid2,Cited2,Sav1,Gja1 |
| 3.015e-02 | -3.50 | trophoblast giant cell differentiation | biological process | GO:0060707 | 18 | 4 | 20694 | 1406 |
Socs3,Itgav,Lif,Prdm1 |
| 3.015e-02 | -3.50 | regulation of early endosome to late endosome transport | biological process | GO:2000641 | 18 | 4 | 20694 | 1406 |
Rab21,Ezr,Map2k1,Src |
| 3.015e-02 | -3.50 | negative regulation of myotube differentiation | biological process | GO:0010832 | 18 | 4 | 20694 | 1406 |
Cflar,Daxx,Notch1,Cxcl10 |
| 3.015e-02 | -3.50 | venous blood vessel development | biological process | GO:0060841 | 18 | 4 | 20694 | 1406 |
Ahr,Acvrl1,Notch1,Sema3c |
| 3.015e-02 | -3.50 | positive regulation of gluconeogenesis | biological process | GO:0045722 | 18 | 4 | 20694 | 1406 |
Hif1a,Sirt1,Ptpn2,Kat2b |
| 3.015e-02 | -3.50 | negative regulation of vascular smooth muscle cell proliferation | biological process | GO:1904706 | 18 | 4 | 20694 | 1406 |
Sod2,Cdkn1a,Il10,Hmox1 |
| 3.015e-02 | -3.50 | negative regulation of T cell receptor signaling pathway | biological process | GO:0050860 | 18 | 4 | 20694 | 1406 |
Ezr,Ptprj,Prnp,Ptpn2 |
| 3.018e-02 | -3.50 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN | 170 | 21 | 15632 | 1249 |
Pde4b,Slc31a2,Nfkb1,Timp1,Mtus1,Tap2,Rhof,Sik3,Trip10,H2-Aa,4932438A13Rik,Tapbp,Ppp2r3a,Tlr3,Ddx60,Stat1,Hmox1,Asap3,Slco3a1,Rab20,Cd34 |
| 3.018e-02 | -3.50 | GSE3982_MAST_CELL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_BASOPHIL_DN | 170 | 21 | 15632 | 1249 |
Vcpip1,Ptges,Actb,Myd88,Pilra,Slco3a1,Osgin2,Apba1,H2-Q7,Evl,Ppp2r5a,Peli1,Isg20,Ets2,Ptpn2,Sema3c,H2-Q6,Cx3cr1,H2-Q4,Parp8,Dusp1 |
| 3.018e-02 | -3.50 | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 170 | 21 | 15632 | 1249 |
Mark2,Itga4,Fam111a,Nxf1,Asb13,Pigv,Akt3,Rap1gap2,Samd9l,Pou2f2,Xaf1,Ctu1,Rnf114,Sesn3,Plekha5,Rab32,Dync1h1,Gsdmd,Cited2,Klf2,B4galt4 |
| 3.018e-02 | -3.50 | GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_DN | MSigDB lists | GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_DN | 170 | 21 | 15632 | 1249 |
Nfxl1,Herc3,Cutc,Ccl22,Nkiras1,Plagl1,Kmo,Phyh,Mcm6,Spata5l1,Ch25h,Rars,Spint2,Etv6,Pou2f2,Nat2,Mcm9,Nlrc4,Ttc9c,Ppp1r15b,Psip1 |
| 3.027e-02 | -3.50 | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP | MSigDB lists | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP | 160 | 20 | 15632 | 1249 |
Gsta3,Cd80,Ikbke,Inpp1,Traf5,Traf1,Sell,Pttg1,Ddx58,Stat1,Etnk1,Tlr1,Tnfsf8,Inpp5b,Parp14,Casp1,Ddhd1,Parp8,Ifit1bl2,Ifit1bl1 |
| 3.027e-02 | -3.50 | GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN | MSigDB lists | GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN | 160 | 20 | 15632 | 1249 |
Ets2,Sipa1l1,Pde4b,Usp53,Treml2,Mdn1,Zeb1,Peli1,Myc,Tnfsf8,Tlr1,Ccnd2,Lrch3,Cd55,Bcor,Pim2,Rab3ip,Tagap,Rras2,Znrf1 |
| 3.027e-02 | -3.50 | GSE3982_BCELL_VS_NKCELL_DN | MSigDB lists | GSE3982_BCELL_VS_NKCELL_DN | 160 | 20 | 15632 | 1249 |
Ppp2r5a,Htra1,Msr1,Acpp,Itgal,N4bp1,Txnrd1,Xcr1,Samhd1,Atp2b4,Pkp4,Extl2,Nlrp3,Tpx2,Adrb2,Slc43a3,Rcan1,Fpr2,Palld,Sema4c |
| 3.033e-02 | -3.50 | - | gene3d domains | 3.30.40.10 | 438 | 49 | 8819 | 755 |
Kdm4a,Znrf1,Pml,Ankib1,Cop1,Rnf19b,Traf5,Trim30a,Dtx2,Pcgf5,Nsd3,Cnot4,Rnf135,Trim12a,Mllt6,Trafd1,Znrf3,Plekhf2,Trim26,Trim13,Rnf114,Rnf31,Trim30d,Kdm5b,Trim56,Wdfy1,Trim12c,Phf11b,Bfar,Rnf19a,Rffl,Rnf139,Pikfyve,Phf11a,Phf6,Dtx3l,Rnf24,Mid1,Mul1,Traf2,Trim21,Rnf34,Phf11c,Rnf145,Birc3,Trim34a,Mdm2,Rnf14,Phf11d |
| 3.035e-02 | -3.50 | OCT1_B | MSigDB lists | OCT1_B | 242 | 28 | 15632 | 1249 |
Slc39a13,Cd180,Prdm1,Csrnp1,Notch1,Lipg,Ifit2,Cpd,Mid1,Egr2,Lyn,Pik3cd,Pim2,H3f3b,Zhx2,Cd86,Rel,Nos2,Abtb2,Rgl1,Sesn3,Dusp6,Csf3,Stat4,Slc25a12,Ppp2r3a,Adora2a,Kctd12 |
| 3.035e-02 | -3.50 | CACCCBINDINGFACTOR_Q6 | MSigDB lists | CACCCBINDINGFACTOR_Q6 | 242 | 28 | 15632 | 1249 |
Il2rg,Itga5,Ptprj,Sema4c,Cdkn1a,Zhx2,Osm,Ptch1,Serpine1,Lad1,Brd2,Jarid2,Rap1gap2,G3bp2,Rtn2,Sdc1,Hif1a,F11r,Usp25,Dusp14,Etv5,Bmp2,Trp53i11,Cited2,Rgs14,Tagln,Phldb1,Spry2 |
| 3.044e-02 | -3.49 | Tnf (tumor necrosis factor) | protein interactions | 21926 | 32 | 7 | 7778 | 753 |
Ikbkg,Tnip1,Tnfaip3,Rnf31,Fubp1,Zfp36,Tnfrsf1b |
| 3.046e-02 | -3.49 | SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 | MSigDB lists | SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 | 413 | 44 | 15632 | 1249 |
Ak4,Gpd2,Mcm6,Mthfd2,Dck,Ripk2,Pgk1,Wdr43,Vrk2,Dr1,Plod2,Psat1,Cdyl,Tuba4a,Ccne1,Gch1,Wars,Hk2,Hat1,Il18rap,Egln3,Tmeff1,Sap30,Trip13,Slc7a5,Pttg1,Tpx2,Cdk5r1,Mcm10,Magohb,Cdkn2d,Rbl1,Slc16a1,Dnaja1,Gpsm2,Hmga1,Slc2a1,Cenpe,Slc16a3,Sod2,Apobec3,Srm,Pnp2,Carhsp1 |
| 3.046e-02 | -3.49 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN | 413 | 44 | 15632 | 1249 |
Max,Endod1,Itpkc,Trib3,Osgin2,Azi2,Rbms1,Notch2,Orai2,Cflar,Clcn7,Asf1a,Tax1bp1,Ikbke,Slc7a8,Brd2,Hk1,Tor1aip1,Lcn2,Casp4,Rapgef2,Eef1e1,Mxd1,Rars,Itga4,Mapkapk2,Dtwd1,Arg2,Isg15,Smg7,Tnfrsf14,Enpp4,Ahr,Aoah,Cst7,Psip1,Jun,Irgq,Bnip3,Slc39a4,Mid1,Nqo1,Gadd45g,Triobp |
| 3.046e-02 | -3.49 | NACHT | prosite domains | PS50837 | 31 | 6 | 13278 | 1037 |
Nlrc4,Nlrc5,Nod1,Ciita,Nod2,Nlrp3 |
| 3.050e-02 | -3.49 | CHYLA_CBFA2T3_TARGETS_DN | MSigDB lists | CHYLA_CBFA2T3_TARGETS_DN | 211 | 25 | 15632 | 1249 |
Tcea1,Agpat4,Cd82,Spire1,Ell2,Mmp9,Oasl1,Ptk2,AA467197,Eya4,Ampd3,Isg20,Irf7,Lcn2,Asns,S100a8,Ppm1l,Sphk1,Pcx,Nqo1,Carhsp1,Mmp14,Dusp8,Gpsm2,P4ha2 |
| 3.062e-02 | -3.49 | Socs3 (suppressor of cytokine signaling 3) | protein interactions | 12702 | 13 | 4 | 7778 | 753 |
Jak2,Nod2,Lmo4,Ptk2 |
| 3.062e-02 | -3.49 | Bcar1 (breast cancer anti-estrogen resistance 1) | protein interactions | 12927 | 13 | 4 | 7778 | 753 |
Ptk2,Crkl,Src,Nck1 |
| 3.062e-02 | -3.49 | ACTN4 (actinin alpha 4) | protein interactions | 81 | 13 | 4 | 7778 | 753 |
Tmod3,Flnb,Actb,Fcho2 |
| 3.068e-02 | -3.48 | CRX_NRL_DN.V1_DN | MSigDB lists | CRX_NRL_DN.V1_DN | 111 | 15 | 15632 | 1249 |
Bambi,Clic4,Sdc4,Frmd6,Kif5c,Egr1,Prdm1,Adrb2,Pnp2,Ntng2,Tnc,Fabp7,Nfkb1,Nr4a1,Fzd5 |
| 3.071e-02 | -3.48 | deaminase activity | molecular function | GO:0019239 | 26 | 5 | 20217 | 1400 |
Adar,Zbp1,Ampd3,Gda,Apobec3 |
| 3.071e-02 | -3.48 | insulin receptor binding | molecular function | GO:0005158 | 26 | 5 | 20217 | 1400 |
Snx2,Igf1r,Phip,Src,Irs2 |
| 3.071e-02 | -3.48 | histone demethylase activity | molecular function | GO:0032452 | 26 | 5 | 20217 | 1400 |
Kdm4a,Kdm6b,Kdm5b,Jmjd6,Jarid2 |
| 3.079e-02 | -3.48 | GAGCCTG_MIR484 | MSigDB lists | GAGCCTG_MIR484 | 92 | 13 | 15632 | 1249 |
Hivep2,Eif4g2,Dach1,Triobp,Kdm4a,Acvr1b,Nfkbiz,Ptger4,Mapkapk2,Dcbld2,Snn,Pcdh7,Znrf1 |
| 3.084e-02 | -3.48 | endopeptidase inhibitor activity | molecular function | GO:0004866 | 196 | 21 | 20217 | 1400 |
Bcl2a1d,Cst7,Serpina3f,Birc3,Slpi,Serpinb9,Serpinb2,C3,Serpinb9b,Ctla2b,Tnfsf14,Crim1,Serpina3g,Prdx5,Birc2,Serpine1,Wfdc17,Pttg1,Serpinb6b,Spint2,Timp1 |
| 3.087e-02 | -3.48 | endopeptidase complex | cellular component | GO:1905369 | 65 | 9 | 20747 | 1409 |
Psma6,Psmb6,Psmb8,Psmb10,Psmd10,Psmb9,Dnajb2,Psme1,Usp25 |
| 3.092e-02 | -3.48 | phosphatidylinositol phosphorylation | biological process | GO:0046854 | 45 | 7 | 20694 | 1406 |
Pikfyve,Pik3cd,Socs7,Socs3,Inpp1,Cish,Socs1 |
| 3.092e-02 | -3.48 | regulation of glycolytic process | biological process | GO:0006110 | 45 | 7 | 20694 | 1406 |
Ddit4,Nupr1,Hif1a,Stat3,Ier3,Htr2a,Myc |
| 3.092e-02 | -3.48 | regulation of posttranscriptional gene silencing | biological process | GO:0060147 | 45 | 7 | 20694 | 1406 |
Mecp2,Nfkb1,Adar,Zc3h12a,Zfp36,Map2k1,Stat3 |
| 3.092e-02 | -3.48 | regulation of gene silencing by RNA | biological process | GO:0060966 | 45 | 7 | 20694 | 1406 |
Nfkb1,Mecp2,Stat3,Map2k1,Zfp36,Zc3h12a,Adar |
| 3.094e-02 | -3.48 | Signaling of Hepatocyte Growth Factor Receptor | WikiPathways | WP193 | 34 | 8 | 4813 | 540 |
Stat3,Crkl,Fos,Src,Ptk2,Jun,Met,Map2k1 |
| 3.094e-02 | -3.48 | p38 MAPK Signaling Pathway | WikiPathways | WP350 | 34 | 8 | 4813 | 540 |
Myc,Daxx,Stat1,Mapkapk2,Pla2g4a,Map2k4,Max,Traf2 |
| 3.094e-02 | -3.48 | Ccnd1 (cyclin D1) | protein interactions | 12443 | 19 | 5 | 7778 | 753 |
Hspa1b,Fbxo4,Myc,Cdkn1a,Hdac1 |
| 3.095e-02 | -3.48 | neuroepithelial cell differentiation | biological process | GO:0060563 | 65 | 9 | 20694 | 1406 |
Jag1,Notch1,Clic5,Bmp2,Gfi1,Slc4a7,Triobp,Fam20c,Sec24b |
| 3.111e-02 | -3.47 | BASAKI_YBX1_TARGETS_UP | MSigDB lists | BASAKI_YBX1_TARGETS_UP | 253 | 29 | 15632 | 1249 |
Sco1,Cacybp,Plk2,Cav1,Rrs1,Tuba4a,Sh3bp4,Hat1,Trip13,Slc7a5,Pdlim7,Flnb,Adrb2,Psmb6,Pmepa1,Frmd6,Dr1,Thbs1,Nfkbia,Plac8,Axl,Rbpms,Slc39a4,Pttg1,Cyth3,Tpx2,Mcm10,Rnd3,Ahsa1 |
| 3.111e-02 | -3.47 | AP1_Q2_01 | MSigDB lists | AP1_Q2_01 | 253 | 29 | 15632 | 1249 |
Snx10,Eno2,Brd2,Slc9a1,Akt3,Dgka,Vasp,Adora2a,Rap1gap2,Itpkc,Trib1,Il1rn,Col27a1,Hcls1,Rap2c,Agpat4,H3f3b,Cdkn1a,Dync1h1,Src,Sqstm1,Tcf4,S1pr2,Mecp2,Rbpms,Cxcl14,Stk40,Olr1,Dusp14 |
| 3.123e-02 | -3.47 | CCCACAT_MIR2993P | MSigDB lists | CCCACAT_MIR2993P | 47 | 8 | 15632 | 1249 |
Cd164,Foxp4,Znfx1,Tcf4,Pdzd11,Ifit1bl2,Ifit1bl1,Itgav |
| 3.123e-02 | -3.47 | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY | MSigDB lists | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY | 47 | 8 | 15632 | 1249 |
Prdx5,Cst7,Birc3,Serpinb9,Birc2,Pttg1,Nlrc4,Tnfsf14 |
| 3.123e-02 | -3.47 | BURTON_ADIPOGENESIS_7 | MSigDB lists | BURTON_ADIPOGENESIS_7 | 47 | 8 | 15632 | 1249 |
Nqo1,Ccnd1,Pnp2,Vcam1,Timp1,Tgfbi,Plac8,Marcksl1 |
| 3.123e-02 | -3.47 | GO_CARDIAC_SEPTUM_MORPHOGENESIS | MSigDB lists | GO_CARDIAC_SEPTUM_MORPHOGENESIS | 47 | 8 | 15632 | 1249 |
Cited2,Notch1,Acvr1,Jag1,Mdm2,Fzd1,Notch2,Sav1 |
| 3.123e-02 | -3.47 | Glycosaminoglycan biosynthesis - keratan sulfate | KEGG pathways | mmu00533 | 14 | 4 | 7931 | 713 |
B4galt4,Fut8,St3gal1,St3gal3 |
| 3.123e-02 | -3.47 | Glycosaminoglycan biosynthesis - keratan sulfate | KEGG pathways | ko00533 | 14 | 4 | 7931 | 713 |
St3gal1,Fut8,St3gal3,B4galt4 |
| 3.133e-02 | -3.46 | positive regulation of histone modification | biological process | GO:0031058 | 97 | 12 | 20694 | 1406 |
Arid5a,Pml,Jarid2,Sirt1,Bcl6,Nsd3,Daxx,Jdp2,Kat2b,Mecp2,Atm,Lif |
| 3.133e-02 | -3.46 | GO_POSITIVE_REGULATION_OF_HOMEOSTATIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_HOMEOSTATIC_PROCESS | 191 | 23 | 15632 | 1249 |
Syk,Tnf,Pla2g4a,Edn1,Gpr68,Pml,Nr1h3,Isg15,Hif1a,Ccl5,Ednrb,H2-Eb1,Atm,Cav1,Hap1,Inhba,Ptger4,Cxcl10,Ptgs2,Acvr1b,Sec24a,Hcar2,Il1b |
| 3.133e-02 | -3.46 | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP | 191 | 23 | 15632 | 1249 |
Mob3b,Dnajb4,Chic2,Sema4a,Serpinb9,Smox,5430427O19Rik,Nfil3,Idi1,Sesn3,Tnfrsf1b,Trim21,Phlda1,Mpp7,Magohb,H2-Q7,Lrp8,Rbms2,Herc3,H2-Q6,H2-Q4,B3gnt5,Tmem171 |
| 3.135e-02 | -3.46 | GO_REGULATION_OF_REPRODUCTIVE_PROCESS | MSigDB lists | GO_REGULATION_OF_REPRODUCTIVE_PROCESS | 121 | 16 | 15632 | 1249 |
Inhba,Pde5a,Timp1,P2ry2,Osm,Cited2,Dusp1,Ednrb,Notch1,Plau,Acvr1b,Ptafr,Prdm9,Ptger4,Lif,Nupr1 |
| 3.135e-02 | -3.46 | GSE13173_UNTREATED_VS_IL12_TREATED_ACT_CD8_TCELL_DN | MSigDB lists | GSE13173_UNTREATED_VS_IL12_TREATED_ACT_CD8_TCELL_DN | 121 | 16 | 15632 | 1249 |
Cx3cr1,Nr4a1,Ahrr,Ppp1r15b,Samsn1,Cysltr2,Casp3,Mdm2,Mmd,Phactr4,Grina,Hinfp,Dek,Idi1,Apaf1,Dnajb2 |
| 3.142e-02 | -3.46 | MODULE_37 | MSigDB lists | MODULE_37 | 403 | 43 | 15632 | 1249 |
Plekhg1,Tuba4a,Gja1,Hsd17b12,Ppp4r2,Timeless,Csf1,Trim14,Ptgs2,Tnfsf4,Larp1,Abcc1,Nfil3,Vegfc,Gca,Chd9,Clcf1,Cited2,Cd302,Fos,Arid5a,Plekhf2,Hivep2,Morc3,Gpr68,Acvr1,Kdm5b,Sele,Mmp14,Stat3,Edn1,Nxf1,Fpr2,Kat2b,Ddx60,Prdm1,Mcmbp,Ncoa7,Smg7,Slamf7,Zbtb5,Sav1,Mapkbp1 |
| 3.151e-02 | -3.46 | PDZ domain binding | molecular function | GO:0030165 | 117 | 14 | 20217 | 1400 |
Plekha2,Cacna1d,Crim1,Atp2b4,Dock4,Rapgef2,Adgrl2,Apba1,Lpar1,Fzd1,Gng12,Sdc2,Gja1,F11r |
| 3.166e-02 | -3.45 | GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_UP | 181 | 22 | 15632 | 1249 |
Reps1,Rap1gap2,Il12rb1,Myadm,Tuba4a,Cd86,Osbpl3,Cmklr1,Cdkn1a,Agpat4,Casp7,Sema4a,Rcn1,Cd200r4,Errfi1,Fgl2,Hdac1,Ogfrl1,Cenpe,Tnks1bp1,Clcn5,Lrp8 |
| 3.166e-02 | -3.45 | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_4H_DN | MSigDB lists | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_4H_DN | 181 | 22 | 15632 | 1249 |
Tmem229b,Irf1,Kif3c,Mtdh,Mcoln2,Dtx2,Rhoh,Pim2,Cd200,Mapkapk2,Notch1,Clcn5,Irf8,Gna15,Asns,Eif4g2,Plac8,Ppp1r14b,Adora2a,Ddit4,Ociad1,Slpi |
| 3.166e-02 | -3.45 | ATACTGT_MIR144 | MSigDB lists | ATACTGT_MIR144 | 181 | 22 | 15632 | 1249 |
Fndc3a,Ell2,Trib1,Pim1,Usp42,Arid5b,Rpgrip1l,Zcchc2,Gcnt2,Lhx2,Eif4g2,Fosb,Nrp2,Hat1,Pde7b,Calcrl,Ncoa7,Slc7a11,Agrn,Nr3c1,Zfp800,Rin2 |
| 3.166e-02 | -3.45 | GSE22432_CDC_VS_COMMON_DC_PROGENITOR_UP | MSigDB lists | GSE22432_CDC_VS_COMMON_DC_PROGENITOR_UP | 181 | 22 | 15632 | 1249 |
Chic2,Tab2,Rcsd1,Gpd2,Nr4a3,Atf3,Rnf139,Traf3ip2,Traf5,Notch2,Ciita,Hcls1,Gna15,Lcp2,Birc3,Gramd1a,Klf3,Tshz1,Psd4,Rapgef2,Tmem26,Icosl |
| 3.166e-02 | -3.45 | GSE3982_NEUTROPHIL_VS_TH1_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH1_DN | 181 | 22 | 15632 | 1249 |
Esd,Stard7,Xcr1,Gfi1,Osbpl3,Rcan1,Odc1,Rcn1,Hmgcs1,Cd200,Eef1e1,Phlda1,Il10,Lnpep,Bfar,Pttg1,Dtwd1,Traf1,Rars,Stard5,Myc,Spsb1 |
| 3.166e-02 | -3.45 | GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN | 181 | 22 | 15632 | 1249 |
Tpi1,Nfkbil1,Ddx60,Sass6,Irs2,Arrdc4,Acvr1b,Gpc1,Sgk3,Gtpbp2,Trafd1,Slc7a11,Cenpe,Zyx,Eno1,Heatr6,Batf2,Slc2a6,Mlkl,Rapgef2,Slamf9,Mdm2 |
| 3.166e-02 | -3.45 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_UP | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_UP | 181 | 22 | 15632 | 1249 |
Pde3b,Sgk3,Myo10,Rab3ip,Tulp3,Ifi44,Acvrl1,Treml2,Ctu1,Spsb1,Gpr18,Tspan3,Otud1,Ldlr,Spata5l1,Ddx4,Tuba4a,Pde4b,4930523C07Rik,Lmo4,Rims3,Cnp |
| 3.173e-02 | -3.45 | Cyclin-like | interpro domains | IPR013763 | 34 | 6 | 19984 | 1430 |
Ccnd2,Ccnj,Ccng2,Ccne1,Rbl1,Ccnd1 |
| 3.175e-02 | -3.45 | Tyr_Pase_AS | interpro domains | IPR016130 | 72 | 10 | 19984 | 1430 |
Dusp8,Ptpn2,Dusp1,Dusp2,Mtmr14,Dusp14,Dusp5,Ptprj,Dusp4,Dusp16 |
| 3.178e-02 | -3.45 | COREBINDINGFACTOR_Q6 | MSigDB lists | COREBINDINGFACTOR_Q6 | 243 | 28 | 15632 | 1249 |
Ccr1,Jdp2,Rilpl1,Vasn,Mmp13,Cd69,Rnf19b,Tnfsf4,Phf6,Nr4a3,Mafg,Rgs1,Ccl4,Tagap,Nr4a1,Prokr1,B3gnt5,Ube2e1,Nfkbiz,Hlx,Lif,Stat2,Pigv,Batf,Col4a2,Pde3b,Pdgfc,Tle3 |
| 3.191e-02 | -3.44 | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP | 171 | 21 | 15632 | 1249 |
Ccr1,Psd4,Dhrs9,Klf2,Tnfsf14,Atp6v1d,Mgat1,Tnfsf15,Pnp2,Stard5,Ppp2r5a,Acvr1,Zfp324,Atf3,Trib1,Ubash3b,Sertad3,Zcchc2,Cd164,Dusp14,Tle3 |
| 3.191e-02 | -3.44 | GSE3691_IFN_PRODUCING_KILLER_DC_VS_PLASMACYTOID_DC_SPLEEN_DN | MSigDB lists | GSE3691_IFN_PRODUCING_KILLER_DC_VS_PLASMACYTOID_DC_SPLEEN_DN | 171 | 21 | 15632 | 1249 |
Pkp4,Ppa1,Magohb,Serpinb9,Nsmaf,Fam111a,Adora2b,Tmem229b,Etv6,Eya4,Cdyl2,Wars,Vcan,Plek,Tpst1,Lap3,Casp4,Gbp7,Pik3r6,Rrs1,Cd274 |
| 3.191e-02 | -3.44 | GSE24210_TCONV_VS_TREG_DN | MSigDB lists | GSE24210_TCONV_VS_TREG_DN | 171 | 21 | 15632 | 1249 |
Ptprj,Naa25,Ddx60,Tpi1,Rtn1,Prnp,Pgm1,Cd300lf,Crim1,Tor3a,Ppp1r15b,Spic,Zc3h12c,Gclm,Gpr84,Zeb1,Ifi44,Slc39a4,Csf3,Slc39a14,Car13 |
| 3.192e-02 | -3.44 | Hedgehog 'off' state | REACTOME pathways | R-MMU-5610787 | 93 | 14 | 8608 | 757 |
Tulp3,Psmb9,Prkar2b,Psme1,Psmb6,Psmb10,Psmb8,Intu,Rpgrip1l,Psme2b,Psmd10,Psma6,Ptch1,Psme2 |
| 3.195e-02 | -3.44 | ECM proteoglycans | REACTOME pathways | R-MMU-3000178 | 28 | 6 | 8608 | 757 |
Serpine1,Tnc,Itgav,Itga9,Agrn,Vcan |
| 3.202e-02 | -3.44 | GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGM_BCELL_DN | MSigDB lists | GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGM_BCELL_DN | 102 | 14 | 15632 | 1249 |
Cenpj,Ccnj,Vcan,Zc3h7a,Peli1,Hmgcs1,Ripk2,Apba1,Tnfrsf14,Gfi1,Plagl2,Ciita,Dek,Rap2c |
| 3.202e-02 | -3.44 | GO_POSITIVE_REGULATION_OF_LIGASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_LIGASE_ACTIVITY | 102 | 14 | 15632 | 1249 |
Arrdc4,Psmb10,Trib3,Psmb6,Psme1,Ube2e1,Ripk3,Psmb9,Psmd10,Dcun1d3,Psmb8,Psma6,Psme2,Gclm |
| 3.202e-02 | -3.44 | MODULE_576 | MSigDB lists | MODULE_576 | 102 | 14 | 15632 | 1249 |
Clic4,Cd14,Bmp2,Plaur,Lhx2,Tnfrsf14,H3f3b,Glrx,Prdm1,Mppe1,Lyn,Slc9a1,Mecp2,Slc25a37 |
| 3.202e-02 | -3.44 | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | MSigDB lists | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | 102 | 14 | 15632 | 1249 |
Atp2b4,Pbx1,Lox,Asap3,Lztfl1,Kdm5b,Stat4,Hspa2,Slpi,Rtn2,Daam1,Plod2,Tcf4,Ltbp2 |
| 3.202e-02 | -3.44 | GO_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS | MSigDB lists | GO_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS | 102 | 14 | 15632 | 1249 |
Il1b,Angpt1,Ust,Il15,St3gal6,Pim1,St3gal3,St3gal1,Chst11,Vcan,Slc9a1,Dse,B4galt4,Abcc5 |
| 3.203e-02 | -3.44 | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_UP | MSigDB lists | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_UP | 141 | 18 | 15632 | 1249 |
Igf2bp2,Igf1r,Crim1,Slc28a2,Sgcb,Ikbke,Irak2,Il18bp,Mafk,Mlkl,Leng9,Scn1b,Tlr1,Cp,Igsf6,Klhl25,Dock4,Mfap3l |
| 3.203e-02 | -3.44 | GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_DN | MSigDB lists | GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_DN | 141 | 18 | 15632 | 1249 |
Kdm6b,Irf2,Egr1,Grina,Slco3a1,Rbms2,Ust,Aff1,Olr1,Ahr,Ifit1bl1,Ifit1bl2,Gypc,Csf3r,Atxn7l1,Pou2f2,Dcp1a,Leng9 |
| 3.203e-02 | -3.44 | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_HET_DN | MSigDB lists | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_HET_DN | 141 | 18 | 15632 | 1249 |
Bcl2a1b,Gadd45b,Flt1,Abtb2,Pde4b,Plac8,Bcl2a1d,Stat3,Ptgs2,Traf3ip2,Ell2,Socs3,Lrp11,Plat,Fcgr1,Cxcl1,Kif9,Bcl2a1a |
| 3.203e-02 | -3.44 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_1H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_1H_ACT_CD4_TCELL_UP | 141 | 18 | 15632 | 1249 |
Nfil3,Tagap,Socs3,Ptgir,Nfkbiz,Rtp4,Socs1,Cish,Tlr1,Casp3,Irgm2,Mid1,Adhfe1,Ttc9c,Pde4b,Tpst1,Cd274,Gpr18 |
| 3.207e-02 | -3.44 | GO_CARBOHYDRATE_HOMEOSTASIS | MSigDB lists | GO_CARBOHYDRATE_HOMEOSTASIS | 161 | 20 | 15632 | 1249 |
Hif1a,Icam1,Irs2,Fas,Ptger4,Oas1g,Hk3,Il1b,Plau,Slc16a1,Ptch1,Ptpn2,Pdk3,Hk1,Ncoa5,Oas1a,Sirt1,Hk2,Stat3,Il6 |
| 3.207e-02 | -3.44 | GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_DN | MSigDB lists | GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_DN | 161 | 20 | 15632 | 1249 |
Cd82,Cd80,Osbpl3,Mdfic,Mcoln2,Fas,Dennd1b,Il6,Slc9a1,G3bp2,Il12rb1,Csrp1,Ccne1,Psip1,Txn1,Src,Tor3a,Jun,Lmo4,Samsn1 |
| 3.207e-02 | -3.44 | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 161 | 20 | 15632 | 1249 |
Snx10,Morc3,Rel,Irf8,Csf1,Pstpip2,Dgka,Cdkn2d,Usp25,Dck,Endod1,Pik3cd,Fam111a,Cd74,Plagl1,Gca,Notch2,Sp110,Snn,Esd |
| 3.212e-02 | -3.44 | PRC1_BMI_UP.V1_UP | MSigDB lists | PRC1_BMI_UP.V1_UP | 151 | 19 | 15632 | 1249 |
Gadd45g,Mafk,Peli1,Egr2,Slpi,Dusp2,Tor1aip2,Ccr3,Edn1,Adap2,Irf8,Birc3,Pmepa1,Tnfaip3,Clec4e,Mmp25,Cxcl10,Ccnd2,Dcp2 |
| 3.230e-02 | -3.43 | antioxidant activity | molecular function | GO:0016209 | 85 | 11 | 20217 | 1400 |
Prdx1,Txnrd1,Sod2,Nqo1,Ptgs2,Selenow,Hp,Gsr,S100a8,Srxn1,Prdx5 |
| 3.230e-02 | -3.43 | kinase activator activity | molecular function | GO:0019209 | 85 | 11 | 20217 | 1400 |
Spry2,Irgm2,Mtcp1,Cdk5r1,Malt1,Daxx,Ccl5,Lgals9,Cdkn1a,Map2k1,Rgcc |
| 3.233e-02 | -3.43 | BARIS_THYROID_CANCER_DN | MSigDB lists | BARIS_THYROID_CANCER_DN | 56 | 9 | 15632 | 1249 |
Tnfsf10,Igf1r,Ccnd1,Sp110,Il13ra1,Dusp6,Irf1,Timp1,Ccnd2 |
| 3.234e-02 | -3.43 | GO_NEURAL_CREST_CELL_DIFFERENTIATION | MSigDB lists | GO_NEURAL_CREST_CELL_DIFFERENTIATION | 74 | 11 | 15632 | 1249 |
Sema3c,Ednrb,Acvr1,Jag1,Phactr4,Edn1,Hif1a,Sema4a,Sema4c,Htr2b,Kitl |
| 3.234e-02 | -3.43 | GO_RHO_GTPASE_BINDING | MSigDB lists | GO_RHO_GTPASE_BINDING | 74 | 11 | 15632 | 1249 |
Rhoh,Nox1,Cdc42ep4,Cdc42ep2,Whamm,Fmnl2,Dock4,Cyfip1,Daam1,Cav1,Triobp |
| 3.234e-02 | -3.43 | GO_PHOSPHATASE_REGULATOR_ACTIVITY | MSigDB lists | GO_PHOSPHATASE_REGULATOR_ACTIVITY | 74 | 11 | 15632 | 1249 |
Ppp2r3a,Phactr4,Ppp2r2a,Ppp4r2,Bmp2,Ppp2r5a,Ppp2r1b,Rcan1,Ppp1r15a,Eif2ak2,Ppp1r14b |
| 3.236e-02 | -3.43 | MODULE_573 | MSigDB lists | MODULE_573 | 23 | 5 | 15632 | 1249 |
Cdkn1a,Lcn2,Kat2b,Myc,Tnc |
| 3.236e-02 | -3.43 | GO_NEGATIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION | 23 | 5 | 15632 | 1249 |
Cxcl14,Il18,Cxcl10,Notch1,Tnf |
| 3.236e-02 | -3.43 | LIAN_NEUTROPHIL_GRANULE_CONSTITUENTS | MSigDB lists | LIAN_NEUTROPHIL_GRANULE_CONSTITUENTS | 23 | 5 | 15632 | 1249 |
Mmp9,Ctsc,Lcn2,Fpr1,Mmp13 |
| 3.236e-02 | -3.43 | GO_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION | MSigDB lists | GO_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION | 23 | 5 | 15632 | 1249 |
Ptgs2,Hif1a,Cx3cl1,Cd34,Thbs1 |
| 3.236e-02 | -3.43 | KONDO_COLON_CANCER_HCP_WITH_H3K27ME1 | MSigDB lists | KONDO_COLON_CANCER_HCP_WITH_H3K27ME1 | 23 | 5 | 15632 | 1249 |
Rnaset2b,Rnaset2a,Mapkbp1,Hlx,Pla2g4a |
| 3.236e-02 | -3.43 | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | MSigDB lists | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | 23 | 5 | 15632 | 1249 |
Gng12,Gna15,Gnb4,Gng4,Gng11 |
| 3.236e-02 | -3.43 | MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_UP | MSigDB lists | MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_UP | 23 | 5 | 15632 | 1249 |
Gmppb,Serp1,Rcl1,Ccl12,Srxn1 |
| 3.236e-02 | -3.43 | PID_PRL_SIGNALING_EVENTS_PATHWAY | MSigDB lists | PID_PRL_SIGNALING_EVENTS_PATHWAY | 23 | 5 | 15632 | 1249 |
Cdkn1a,Rhoc,Egr1,Ccne1,Src |
| 3.236e-02 | -3.43 | GO_REGULATION_OF_ODONTOGENESIS | MSigDB lists | GO_REGULATION_OF_ODONTOGENESIS | 23 | 5 | 15632 | 1249 |
Edn1,Csf1,Cd34,Bcor,Bmp2 |
| 3.236e-02 | -3.43 | BRACHAT_RESPONSE_TO_METHOTREXATE_UP | MSigDB lists | BRACHAT_RESPONSE_TO_METHOTREXATE_UP | 23 | 5 | 15632 | 1249 |
Trafd1,Cdkn1a,Mdm2,Carhsp1,Btg2 |
| 3.236e-02 | -3.43 | WEINMANN_ADAPTATION_TO_HYPOXIA_UP | MSigDB lists | WEINMANN_ADAPTATION_TO_HYPOXIA_UP | 23 | 5 | 15632 | 1249 |
Nqo1,Hspa1a,Hspa2,Slc16a3,Hmox1 |
| 3.236e-02 | -3.43 | GO_POSITIVE_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY | 23 | 5 | 15632 | 1249 |
Cd40,C3,Tnfsf4,Tnf,Clcf1 |
| 3.236e-02 | -3.43 | GO_NEUROTROPHIN_SIGNALING_PATHWAY | MSigDB lists | GO_NEUROTROPHIN_SIGNALING_PATHWAY | 23 | 5 | 15632 | 1249 |
Src,Ddit4,Casp3,Hap1,Rapgef2 |
| 3.236e-02 | -3.43 | GO_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS | 23 | 5 | 15632 | 1249 |
Gch1,Nqo1,Nos2,Slc7a2,Arg2 |
| 3.236e-02 | -3.43 | GO_SKELETAL_MUSCLE_TISSUE_REGENERATION | MSigDB lists | GO_SKELETAL_MUSCLE_TISSUE_REGENERATION | 23 | 5 | 15632 | 1249 |
Gja1,Plau,Bcl9,Cflar,Ifrd1 |
| 3.238e-02 | -3.43 | NAD phosphorylation and dephosphorylation | BIOCYC pathways | MOUSE_NADPHOS-DEPHOS-PWY | 8 | 3 | 1025 | 97 |
Acpp,Acp2,Acp5 |
| 3.238e-02 | -3.43 | superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism | BIOCYC pathways | MOUSE_PWY-6358 | 8 | 3 | 1025 | 97 |
Minpp1,Itpkc,Inpp1 |
| 3.242e-02 | -3.43 | mouse chr9 F4|9 75.05 cM | chromosome location | mouse chr9 F4|9 75.05 cM | 5 | 2 | 24173 | 1464 |
Ccr1,Ccr3 |
| 3.244e-02 | -3.43 | PAX2_02 | MSigDB lists | PAX2_02 | 233 | 27 | 15632 | 1249 |
Nfkbia,Fos,Cited2,Tcf4,Cd40,Bcl6,Phgdh,Ccnd1,Cdyl2,Dusp4,Evl,Ccl22,Sdc1,Slco3a1,Il27,Pfkfb3,Etv5,Sesn3,Ptch1,Ascc3,Atxn7l1,Hivep3,Vasn,Rtn1,Lox,Frmd4a,Pcdh7 |
| 3.244e-02 | -3.43 | ETS1_B | MSigDB lists | ETS1_B | 233 | 27 | 15632 | 1249 |
Rgs14,Hmga1,Slc25a37,Zfp800,Treml2,Pml,Lif,Apba1,Csrnp1,Rgs3,Spred1,Extl2,Rbms2,Lcp2,Junb,Map4k4,Rnf31,Etv6,Pdgfb,Psme2,Lyn,Il12b,Sema4c,Ptk2,Cacna1d,Pcdh7,Rap2c |
| 3.245e-02 | -3.43 | regulation of transmembrane transporter activity | biological process | GO:0022898 | 261 | 26 | 20694 | 1406 |
Agrn,Actb,Mmp9,Pde4b,Hk1,Cav1,Gja1,Homer1,Nlgn2,Hspa2,Gem,Glrx,Hap1,Stoml1,Prnp,Gpr35,Ccl2,Slc9a1,Cox17,Cacnb3,Adrb2,Tlr9,Cacna1d,Ptafr,Abcb1a,Scn1b |
| 3.245e-02 | -3.43 | kidney development | biological process | GO:0001822 | 261 | 26 | 20694 | 1406 |
Tet2,Prkx,Notch1,Myc,Tiparp,Rpgrip1l,Arid5b,Pdgfrb,Notch2,Jmjd6,Pbx1,Ahr,Egr1,Ptch1,Gsta3,Odc1,Bmp2,Timeless,Bcl2l11,Angpt1,Lrp4,Jag1,Pdgfb,Cited2,Vcan,Arg2 |
| 3.248e-02 | -3.43 | regulation of hormone levels | biological process | GO:0010817 | 551 | 49 | 20694 | 1406 |
Bmp2,Map4k4,Cd38,Gpr68,Nr3c1,Nos2,Hif1a,Il6,Lif,Il1b,Pim3,Hmga2,Gfi1,Sirt1,Tiparp,Prkce,Hmgn3,Clcf1,Lyn,Inhba,Klf7,Osm,Nfkb1,Jak2,Gja1,Glrx,Dio2,Serp1,Hdac1,Tnf,Rab11fip1,Cacna1d,Abcb1a,Mecp2,Ptger4,Pde3b,Kdm5b,Il1rn,Dhrs9,Egr1,Ccl5,Hcar2,Slc16a1,Irs2,Stxbp3,Edn1,Nlgn2,Pfkl,Igf1r |
| 3.256e-02 | -3.42 | KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN | MSigDB lists | KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN | 202 | 24 | 15632 | 1249 |
H3f3b,Cacna1d,Bcl2a1a,Slamf8,Map2k4,Il13ra1,Spint2,Dgka,Mcm9,Tuba4a,Sav1,Rnd3,Sdc4,Adar,Pbx1,Fgr,Abr,Bcl2a1d,Cyfip1,Csf3r,Cnn2,Morc3,Bcl2a1b,Txnrd1 |
| 3.262e-02 | -3.42 | GCM_DLG1 | MSigDB lists | GCM_DLG1 | 65 | 10 | 15632 | 1249 |
Phlpp2,Cldnd1,Ociad1,Rapgef2,4932438A13Rik,Ccdc25,Map4k4,Ptk2,Sik3,Higd1a |
| 3.262e-02 | -3.42 | TCGA_GLIOBLASTOMA_COPY_NUMBER_UP | MSigDB lists | TCGA_GLIOBLASTOMA_COPY_NUMBER_UP | 65 | 10 | 15632 | 1249 |
Mdm2,Samd9l,Met,Akt3,Fam133b,Ccnd2,Chic2,Parp11,Ankib1,Ppp1r15b |
| 3.262e-02 | -3.42 | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN | MSigDB lists | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN | 65 | 10 | 15632 | 1249 |
F10,Csf1,Il6,Aff1,Pfkl,Acp2,Irf2,Eif4g2,Nampt,Tuba4a |
| 3.263e-02 | -3.42 | WANG_LMO4_TARGETS_UP | MSigDB lists | WANG_LMO4_TARGETS_UP | 307 | 34 | 15632 | 1249 |
Bcor,Nek6,Arrdc4,Arg2,F11r,Sgk3,Dpy19l1,Bcl6,D16Ertd472e,Tiparp,Ets2,Slc2a1,Ubtd2,Rhoq,D1Ertd622e,Rin2,Mtdh,Naa25,Cpeb4,Max,Azi2,Acvr1b,Fam20c,Thbs1,Cflar,Vrk2,Stard7,Abtb2,Fubp1,Rab10,Ociad1,Ddit4,Rhou,Etv6 |
| 3.264e-02 | -3.42 | SOCS_box | pfam domains | PF07525 | 34 | 6 | 18711 | 1348 |
Spsb1,Socs7,Cish,Socs3,Asb13,Socs1 |
| 3.278e-02 | -3.42 | regulation of amyloid precursor protein catabolic process | biological process | GO:1902991 | 36 | 6 | 20694 | 1406 |
Prnp,Casp3,Tnf,Lyn,Hap1,Gsap |
| 3.287e-02 | -3.42 | METALLOTHIONEIN_VRT | prosite domains | PS00203 | 4 | 2 | 13278 | 1037 |
Mt2,Mt1 |
| 3.287e-02 | -3.42 | RETICULON | prosite domains | PS50845 | 4 | 2 | 13278 | 1037 |
Rtn2,Rtn1 |
| 3.287e-02 | -3.42 | ZF_CR | prosite domains | PS51188 | 4 | 2 | 13278 | 1037 |
Dnaja1,Dnaja2 |
| 3.289e-02 | -3.41 | negative regulation of cell cycle process | biological process | GO:0010948 | 213 | 22 | 20694 | 1406 |
Tmem67,Cenpe,Rbl1,Trip13,Dcun1d3,Lif,Atm,Slfn1,Rgcc,Plk3,Ccnd1,Cdkn2d,Osm,Kat2b,Ier3,Gpr132,Mdm2,Ccl12,Casp2,Pml,Pttg1,Cdkn1a |
| 3.290e-02 | -3.41 | GO_PLATELET_AGGREGATION | MSigDB lists | GO_PLATELET_AGGREGATION | 39 | 7 | 15632 | 1249 |
P2ry12,Plek,Stxbp1,Csrp1,Slc7a11,Actb,Stxbp3 |
| 3.290e-02 | -3.41 | WENG_POR_TARGETS_LIVER_UP | MSigDB lists | WENG_POR_TARGETS_LIVER_UP | 39 | 7 | 15632 | 1249 |
Tmem176a,Idi1,Asns,Prnp,Hmox1,Hmgcs1,Gadd45b |
| 3.290e-02 | -3.41 | JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_DN | MSigDB lists | JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_DN | 39 | 7 | 15632 | 1249 |
Rgs1,Kdr,Cd83,Pdgfrb,Pmepa1,Mmp13,Rcl1 |
| 3.290e-02 | -3.41 | chr9q31 | MSigDB lists | chr9q31 | 39 | 7 | 15632 | 1249 |
Prpf4,Slc44a1,Trim14,Tmeff1,Slc31a1,Txn1,Slc31a2 |
| 3.290e-02 | -3.41 | KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_UP | MSigDB lists | KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_UP | 39 | 7 | 15632 | 1249 |
Phlda1,Bcl2a1a,Zeb1,Bcl2a1d,Bcl2a1b,Slc31a2,Acsl1 |
| 3.290e-02 | -3.41 | GO_REGULATION_OF_MEMBRANE_DEPOLARIZATION | MSigDB lists | GO_REGULATION_OF_MEMBRANE_DEPOLARIZATION | 39 | 7 | 15632 | 1249 |
Gja1,Src,Scn1b,Tspo,Gclc,Kdr,Gclm |
| 3.290e-02 | -3.41 | GO_CLATHRIN_COATED_ENDOCYTIC_VESICLE_MEMBRANE | MSigDB lists | GO_CLATHRIN_COATED_ENDOCYTIC_VESICLE_MEMBRANE | 39 | 7 | 15632 | 1249 |
Ldlr,H2-Aa,Fcgr1,H2-Eb1,H2-Ab1,Fzd5,Cd74 |
| 3.290e-02 | -3.41 | GO_ENDODERMAL_CELL_DIFFERENTIATION | MSigDB lists | GO_ENDODERMAL_CELL_DIFFERENTIATION | 39 | 7 | 15632 | 1249 |
Col4a2,Mmp14,Inhba,Itga4,Itga5,Mmp9,Itgav |
| 3.290e-02 | -3.41 | HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_UP | 39 | 7 | 15632 | 1249 |
H2-Ab1,Pim2,Rhoh,Cacnb3,Lmo4,Socs1,Sap30 |
| 3.290e-02 | -3.41 | GO_MYELOID_CELL_DEVELOPMENT | MSigDB lists | GO_MYELOID_CELL_DEVELOPMENT | 39 | 7 | 15632 | 1249 |
Src,Arid4a,Tmod3,Klf2,Bcl6,Jmjd6,Fam20c |
| 3.290e-02 | -3.41 | LUI_THYROID_CANCER_CLUSTER_2 | MSigDB lists | LUI_THYROID_CANCER_CLUSTER_2 | 39 | 7 | 15632 | 1249 |
Trp53i11,Slc7a8,Mfap3l,Slc16a3,Kif5c,Tulp3,Itpr1 |
| 3.296e-02 | -3.41 | G protein-coupled peptide receptor activity | molecular function | GO:0008528 | 140 | 16 | 20217 | 1400 |
Ednrb,Ogfr,Ccr1,Agtrap,Ogfrl1,Xcr1,Ccrl2,Fpr2,Cx3cr1,Gpr84,Gpr35,Cysltr2,Calcrl,Prokr1,Ccr3,Fpr1 |
| 3.301e-02 | -3.41 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_UP | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_UP | 192 | 23 | 15632 | 1249 |
Extl2,Hinfp,Ube2f,Slamf7,Plagl2,Mcm10,Slc30a4,Prnp,Mul1,Rhoq,Carhsp1,Scarf1,Gpr68,Pgk1,Casp7,Odc1,Ier3,Ttc39b,Mthfd2,Noc4l,Hivep3,Cdyl,Pdk3 |
| 3.301e-02 | -3.41 | GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_DN | MSigDB lists | GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_DN | 192 | 23 | 15632 | 1249 |
Ldha,Slc31a1,Traf3ip2,Mthfd2,Wdr43,Prkar2b,Ccne1,Tuba4a,Txn1,Timeless,Trip13,Trim14,Slc39a14,Tpx2,Gclc,Mdfic,Cenpe,Gpsm2,Gclm,Spry2,D1Ertd622e,Phgdh,Cers6 |
| 3.307e-02 | -3.41 | TATA_01 | MSigDB lists | TATA_01 | 223 | 26 | 15632 | 1249 |
Klf2,Il10,Jarid2,Gch1,Ccl5,Tuba4a,Pdlim7,Atxn7l1,Dyrk2,H3f3b,Dio2,Pmepa1,Rgs1,Tnfsf10,Itpr1,Nr4a1,Errfi1,Mid1,Gadd45g,Edn1,Bnip3,Egr2,Gbe1,Cx3cl1,Lif,Prdx1 |
| 3.312e-02 | -3.41 | single-stranded RNA binding | molecular function | GO:0003727 | 96 | 12 | 20217 | 1400 |
Ddx60,Ago3,Polr2g,Ddx58,Ikzf1,Pnpt1,Ifih1,Rbms1,Rbms2,Rbpms,Jmjd6,Dhx58 |
| 3.314e-02 | -3.41 | Metabolism of amino acids and derivatives | REACTOME pathways | R-MMU-71291 | 232 | 29 | 8608 | 757 |
Hdc,Psmb9,Il4i1,Gclc,Odc1,Nqo1,Asns,Psme1,Phgdh,Smox,Dio2,Txnrd1,Psmb6,Psmb10,Psmb8,Ass1,Psmd10,Nmral1,Psma6,Psme2,Gclm,Srm,Arg2,Psat1,Slc7a5,Kmo,Sat1,Ppm1k,Psme2b |
| 3.316e-02 | -3.41 | carboxylic acid metabolic process | biological process | GO:0019752 | 774 | 66 | 20694 | 1406 |
Odc1,Tpi1,Aoah,Ass1,Asns,Ldha,Phyh,Ptgs2,Nos2,Phgdh,P4ha2,Ero1l,Mthfr,Hif1a,Arg2,Acsl1,Txnrd1,Acsl5,Il1b,Mthfd1l,Hk3,Pgk1,Pcx,Ptges,Adhfe1,Nr4a3,Tlr2,Sphk1,Hk2,Acod1,Cemip2,Il4i1,Lipe,Eno2,Pla2g4a,Gch1,Asah2,Mthfd2,Dse,Me1,Rars,Psat1,Egln3,Pdpn,Mecp2,Hdc,Syk,Gfpt1,Plod2,C3,Cd74,Kmo,Dhrs9,Nr1h3,Gclc,Plod3,Gclm,Lipg,Tha1,P4ha1,Hk1,Il15,Prkar2b,Pfkl,Wars,Edn1 |
| 3.317e-02 | -3.41 | hexose biosynthetic process | biological process | GO:0019319 | 27 | 5 | 20694 | 1406 |
Gpd2,Pgk1,Pcx,Atf3,Tpi1 |
| 3.317e-02 | -3.41 | cellular response to lipoprotein particle stimulus | biological process | GO:0071402 | 27 | 5 | 20694 | 1406 |
Syk,Myd88,Hmgcs1,Ldlr,Tlr6 |
| 3.317e-02 | -3.41 | positive regulation of steroid biosynthetic process | biological process | GO:0010893 | 27 | 5 | 20694 | 1406 |
Adora2b,Igf1r,Il1b,Tnf,Il1a |
| 3.317e-02 | -3.41 | positive regulation of neuroblast proliferation | biological process | GO:0002052 | 27 | 5 | 20694 | 1406 |
Vegfc,Cx3cr1,Notch1,Hif1a,Cx3cl1 |
| 3.317e-02 | -3.41 | negative regulation of cell killing | biological process | GO:0031342 | 27 | 5 | 20694 | 1406 |
Lgals9,Tap2,Tap1,Serpinb9,Clec2d |
| 3.317e-02 | -3.41 | negative regulation of calcium-mediated signaling | biological process | GO:0050849 | 27 | 5 | 20694 | 1406 |
Atp2b4,Rcan1,Itpr1,Prnp,Dyrk2 |
| 3.317e-02 | -3.41 | positive regulation of lipid catabolic process | biological process | GO:0050996 | 27 | 5 | 20694 | 1406 |
Acsl5,Irs2,Ldlr,Il1b,Prkce |
| 3.320e-02 | -3.41 | cell cycle | biological process | GO:0007049 | 1148 | 94 | 20694 | 1406 |
Rgs14,Mcm6,Chmp4b,Notch1,Inhba,Sbds,Top3a,Pim1,Vcpip1,Ccne1,Tlk2,Rrs1,Map2k1,Sass6,Mtus1,Mitd1,Src,Smc5,Nek6,Mcmbp,Rhoc,Myc,Spry2,Ccng2,Hspa2,Trip13,Trim21,Triobp,Xrn1,Ezr,Acvr1,Hinfp,Irf1,Map3k8,Rhou,Pnpt1,Slfn1,Mecp2,Azi2,Abcb1a,Cenpe,Cenpj,Pttg1,Tet2,Gpsm2,Pim3,Hmga2,Mdm2,Gpr132,Ier3,Crlf3,Ccnd1,Ahr,Prkce,Spire1,Casp2,Marf1,Ppp2r2a,Gem,Timeless,Thbs1,Plk2,Prdm9,Whamm,Sde2,Syne2,Phgdh,Atm,Ddx4,Ccnd2,Acvr1b,Dusp1,Il12b,Notch2,Slc16a1,Kat2b,Cdkn2d,Rgcc,Kmt5a,Rbl1,Dync1h1,Cdkn1a,Pml,Rbbp8,Katna1,Ccnj,Pim2,Ikzf1,Trim36,Tuba4a,Plk3,Daxx,Tpx2,Setdb2 |
| 3.329e-02 | -3.40 | regulation of multicellular organism growth | biological process | GO:0040014 | 87 | 11 | 20694 | 1406 |
Ikzf1,Stat3,Plac8,Gdf15,Adrb2,Hmga2,Ezr,Ptch1,Csf1,Daxx,Stat5a |
| 3.336e-02 | -3.40 | nucleotidyltransferase activity | molecular function | GO:0016779 | 129 | 15 | 20217 | 1400 |
Oas1b,Oasl2,Cgas,Pnpt1,Tut7,Oas1g,Tent4a,Tent2,Papss2,Oas1a,Oas3,Oasl1,Gmppb,Polr2g,Oas2 |
| 3.341e-02 | -3.40 | GSE40273_XBP1_KO_VS_WT_TREG_DN | MSigDB lists | GSE40273_XBP1_KO_VS_WT_TREG_DN | 182 | 22 | 15632 | 1249 |
Rap1gap2,Ksr1,Flnb,Slpi,Cd86,Pik3r6,Cep350,Sp110,Osbpl3,Fscn1,Clic4,Cd300lf,Tbc1d1,P2ry13,Spn,Cd80,Ccdc88b,Cd180,Traf1,Fas,Itga4,Nek6 |
| 3.341e-02 | -3.40 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | 182 | 22 | 15632 | 1249 |
Pde1b,Slc39a4,Abcc5,Plekha5,Slc7a11,Stat5a,Rgs3,Cd14,Ifih1,Slco3a1,Trim13,Usp25,P2ry2,Mov10,Klf2,Brwd3,Pde4b,Cmpk2,Adrb2,Grina,Dnajb4,St3gal1 |
| 3.341e-02 | -3.40 | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP | 182 | 22 | 15632 | 1249 |
Pdzd11,Pcgf5,Dnajb2,Slc37a3,Tnfsf10,Junb,Spint2,Adora2a,Il12rb1,Bcl9,Rtp4,Rab19,Usp18,Evl,Irak3,Rbms2,B4galt4,Agrn,Ass1,Nlrc5,Stard5,Irf4 |
| 3.341e-02 | -3.40 | GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | MSigDB lists | GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | 182 | 22 | 15632 | 1249 |
Tyk2,Sdc2,Pla2g4a,Plk2,Itgav,Ddhd1,Hsph1,Nampt,Map3k6,Keap1,Gfi1,Cd164,Pnpt1,Cmklr1,Cx3cl1,Ptafr,Irs2,Gbe1,Clec4d,Kif3c,Adora2b,Hif1a |
| 3.341e-02 | -3.40 | GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_UP | MSigDB lists | GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_UP | 182 | 22 | 15632 | 1249 |
B3gnt5,Rasgrp1,Mllt6,Chst11,Cish,Arl5b,Ikzf1,Bcorl1,Inpp5b,Klhl25,N4bp1,Ppp1r15b,Nlrc5,Rbl1,Rhoc,Cd38,Pde3b,Calcrl,4930453N24Rik,Cdkn2d,Pim2,Atp10a |
| 3.341e-02 | -3.40 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDC_UP | 182 | 22 | 15632 | 1249 |
Ccrl2,Stx6,Birc3,Ednrb,Nfkb2,Clec5a,Acsl1,Mefv,Hmgcs1,Peli1,D16Ertd472e,Zyx,Tnf,Usp53,Klf7,Clcn5,Ciita,Pilra,Cd14,Icam1,Trim13,Aim2 |
| 3.341e-02 | -3.40 | GSE17721_12H_VS_24H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_12H_VS_24H_PAM3CSK4_BMDC_DN | 182 | 22 | 15632 | 1249 |
Pim2,Fam111a,Kif3c,Pgk1,Glrx,Sesn3,Pde4b,Mcm9,Klf2,Marco,Phlda1,Dgka,Stat4,Bst1,Mul1,Calcrl,Pgm1,Hif1a,Tal2,Gclc,Slc16a3,Aoah |
| 3.341e-02 | -3.40 | GSE20366_TREG_VS_TCONV_UP | MSigDB lists | GSE20366_TREG_VS_TCONV_UP | 182 | 22 | 15632 | 1249 |
Srxn1,Rab10,Egln3,Ccrl2,Eno2,Cd300lf,Il1rn,Gng12,Egr3,Il18,Casp3,Gsr,Rin2,N4bp1,Itgav,Gnb4,Enpp4,Arg2,Ppm1l,Nlrp3,Plagl1,Prnp |
| 3.341e-02 | -3.40 | GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_DN | MSigDB lists | GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_DN | 182 | 22 | 15632 | 1249 |
Wdr43,Snapc1,Orai2,Calcrl,Ddx58,Pik3cd,Slco3a1,Azi2,Rab20,Slc39a14,Oas2,Gpr18,Acpp,Klf2,Itpr1,Gpsm2,Hmga1,Hivep2,Ass1,Abcc5,Ccne1,Ppp6r1 |
| 3.341e-02 | -3.40 | GSE16266_CTRL_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP | MSigDB lists | GSE16266_CTRL_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP | 182 | 22 | 15632 | 1249 |
Rnf19a,Aebp2,Bcl2a1d,Ddit4,Casp3,Rab10,Egr2,Txn1,Jarid2,Bcl2a1b,Chmp4b,Rbl1,Bcl2a1a,Ube2f,Plagl1,Hif1a,Prnp,Odc1,Sass6,Ube2e1,Smc5,Egr1 |
| 3.341e-02 | -3.40 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP | 182 | 22 | 15632 | 1249 |
Gpd2,Tab2,Itga4,Casp7,Glrx,Apaf1,Bcl2a1a,Acsl5,Batf,Prdx1,Gem,Irf8,Bcl2a1b,Rnf14,Txn1,Snx10,Bcl2a1d,Hk2,Cox17,Hdac1,Carhsp1,Reps1 |
| 3.341e-02 | -3.40 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN | 182 | 22 | 15632 | 1249 |
Socs3,Rhoh,Pgs1,Aldh1b1,Socs1,Traf1,Nr4a3,Ms4a6d,Tulp3,Prnp,Pmepa1,Gfi1,Rab3ip,Axl,Tpst1,Ets2,Gpsm2,Dgka,Spint2,Bst1,Degs2,Hivep3 |
| 3.341e-02 | -3.40 | oxoacid metabolic process | biological process | GO:0043436 | 814 | 69 | 20694 | 1406 |
Mthfr,Acsl1,Arg2,Hif1a,Ero1l,P4ha2,Nos2,Ptgs2,Phgdh,Phyh,Asns,Ldha,Aoah,Ass1,Tpi1,Odc1,Acod1,Cemip2,Lipe,Il4i1,Sphk1,Hk2,Adhfe1,Tlr2,Nr4a3,Pcx,Pgk1,Chst11,Ptges,Mthfd1l,Hk3,Il1b,Txnrd1,Acsl5,Gfpt1,Hdc,Mecp2,Syk,Pdpn,Egln3,Angpt1,Psat1,Me1,Rars,Dse,Mthfd2,Pla2g4a,Gch1,Asah2,Eno2,Edn1,Wars,Pfkl,Prkar2b,Hk1,Il15,Papss2,P4ha1,Tha1,Lipg,Plod3,Gclm,Kmo,Gclc,Nr1h3,Dhrs9,Cd74,C3,Plod2 |
| 3.344e-02 | -3.40 | GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | MSigDB lists | GO_DEVELOPMENTAL_PROCESS_INVOLVED_IN_REPRODUCTION | 548 | 56 | 15632 | 1249 |
Junb,Arid4a,Fzd5,Map2k1,Pdgfb,Inhba,Mmp13,Tlr3,Fndc3a,Ptgs2,Arid5b,Kitl,Il1b,Src,Axl,Insl6,Birc2,Zmynd15,Tnc,Itgb8,Ccnd1,Kdm5b,Acvr1,Hspa2,Prdm1,Nupr1,Lif,Hif1a,Icam1,Il1a,Pbx1,Etv5,Notch1,Dach1,Atm,Ccne1,Il10,Casp8,Csf1,Trip13,Htra1,Sirt1,Casp2,Hmgcs1,Ptk2,Socs3,Acvr1b,Bcl2l11,Tiparp,Cited2,Pla2g4a,Mmp14,Taf4b,Fas,Sdc1,Ahr |
| 3.348e-02 | -3.40 | brain development | biological process | GO:0007420 | 617 | 54 | 20694 | 1406 |
Cx3cr1,Ddit4,Fcgr2b,Hdac1,Apaf1,Met,Ikzf1,P2ry12,Mecp2,Tulp3,Egr2,Pou3f1,Rac3,Kdm6b,Sec24b,Rpgrip1l,Fabp7,Slc4a7,Irs2,Lrp8,Socs7,D16Ertd472e,Igf1r,Stxbp3,Tsku,Ext1,Sema4c,Adgrl2,Hap1,Bmp2,Map2k1,Rapgef2,Lhx2,Nrp2,B3gnt5,Src,Syne2,Abr,Atm,Hif1a,Akt3,Axl,Tal2,Notch1,Hhex,Hmga2,Btg2,Inhba,Slc7a11,Cdk5r1,Nr4a3,Sphk1,Crkl,Ptch1 |
| 3.349e-02 | -3.40 | positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0090100 | 109 | 13 | 20694 | 1406 |
Cited2,Rbpms,Kdr,Acvr1b,Inhba,Notch2,Thbs1,Gdf15,Acvrl1,Lgals9,Acvr1,Bmp2,Notch1 |
| 3.350e-02 | -3.40 | Primary immunodeficiency | KEGG pathways | mmu05340 | 35 | 7 | 7931 | 713 |
Rfx5,Tap2,Ciita,Tap1,Ikbkg,Cd40,Il2rg |
| 3.350e-02 | -3.40 | Primary immunodeficiency | KEGG pathways | ko05340 | 35 | 7 | 7931 | 713 |
Rfx5,Cd40,Il2rg,Tap2,Tap1,Ciita,Ikbkg |
| 3.350e-02 | -3.40 | Fructose and mannose metabolism | KEGG pathways | mmu00051 | 35 | 7 | 7931 | 713 |
Tpi1,Pfkl,Hk3,Hk1,Gmppb,Hk2,Pfkfb3 |
| 3.350e-02 | -3.40 | Fructose and mannose metabolism | KEGG pathways | ko00051 | 35 | 7 | 7931 | 713 |
Hk2,Gmppb,Pfkfb3,Hk3,Pfkl,Tpi1,Hk1 |
| 3.351e-02 | -3.40 | GO_INTRINSIC_COMPONENT_OF_ENDOPLASMIC_RETICULUM_MEMBRANE | MSigDB lists | GO_INTRINSIC_COMPONENT_OF_ENDOPLASMIC_RETICULUM_MEMBRANE | 122 | 16 | 15632 | 1249 |
H2-Ab1,H2-Q7,Rtn1,Cd74,Bfar,Slc37a3,Tap1,H2-Q4,H2-Eb1,Dhrs9,H2-Q6,Tap2,Ext1,Rtn2,H2-Aa,Tapbp |
| 3.351e-02 | -3.40 | MODULE_324 | MSigDB lists | MODULE_324 | 122 | 16 | 15632 | 1249 |
Ppa1,Mmp9,Acsl1,F10,Ldlr,Tnfaip3,Ltbp2,Itgal,Lap3,Cp,Mmp14,Plscr1,Mmp13,Mid1,Dgka,C1ra |
| 3.361e-02 | -3.39 | KASLER_HDAC7_TARGETS_2_DN | MSigDB lists | KASLER_HDAC7_TARGETS_2_DN | 31 | 6 | 15632 | 1249 |
Gadd45b,Nfkbia,Ptch1,Cdkn1a,Klf2,Cacnb3 |
| 3.361e-02 | -3.39 | JIANG_AGING_CEREBRAL_CORTEX_UP | MSigDB lists | JIANG_AGING_CEREBRAL_CORTEX_UP | 31 | 6 | 15632 | 1249 |
Egr2,Actb,Prdx1,Dck,Ube2e1,Gadd45b |
| 3.361e-02 | -3.39 | POS_HISTAMINE_RESPONSE_NETWORK | MSigDB lists | POS_HISTAMINE_RESPONSE_NETWORK | 31 | 6 | 15632 | 1249 |
Jun,Upp1,Asns,Acpp,Arf4,Il15 |
| 3.361e-02 | -3.39 | MMS_MOUSE_LYMPH_HIGH_4HRS_UP | MSigDB lists | MMS_MOUSE_LYMPH_HIGH_4HRS_UP | 31 | 6 | 15632 | 1249 |
Peli1,Dck,Txnrd1,Mark2,Nqo1,Lmo4 |
| 3.368e-02 | -3.39 | basal part of cell | cellular component | GO:0045178 | 66 | 9 | 20747 | 1409 |
Cav1,Itga9,Met,Edn1,Slco3a1,P2ry12,Phldb1,Mark2,Cd34 |
| 3.371e-02 | -3.39 | TGCACTT_MIR519C_MIR519B_MIR519A | MSigDB lists | TGCACTT_MIR519C_MIR519B_MIR519A | 405 | 43 | 15632 | 1249 |
Tnks1bp1,Gda,Hif1a,Nkiras1,Mmp14,Dusp8,Stat3,Triobp,Psd,Acvr1,Mecp2,Cnot4,N4bp1,Gramd1a,Hivep2,Ptpn2,Itpr1,Znfx1,Chd9,Rap2c,Asf1a,Gtpbp2,Zhx2,Frmd6,Dcbld2,Rtn1,Kpna3,Map3k8,Fcho2,Mob3b,Rtn2,Rab10,Akt3,Nrp2,Stx6,Casp2,Rictor,Rnf31,Ccnj,Eif4g2,Slc4a7,Mier3,Arid4a |
| 3.372e-02 | -3.39 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_DN | 172 | 21 | 15632 | 1249 |
Clic4,Rnf34,Osbpl3,Keap1,Prpf38a,Slc37a3,Fam162a,Cd200,Egr3,Pigv,Ier3,Ccl22,Trib3,Ggct,Spint2,Mlkl,Slc39a14,Srm,Ppp1r14b,Rrs1,Homer1 |
| 3.372e-02 | -3.39 | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_UP | 172 | 21 | 15632 | 1249 |
Sema4c,Atf3,Arid5b,Cdk5r1,Irf1,Mob3b,Mppe1,Fcgr1,Trp53i11,Ap3m2,Tle3,Ppfibp2,Src,Crbn,Lcn2,Klf2,Samsn1,Nat2,Rab11fip1,Maff,Dcp1a |
| 3.372e-02 | -3.39 | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | 172 | 21 | 15632 | 1249 |
Zfp324,Snx2,Lipe,Jarid2,Klf3,4930523C07Rik,Tnfrsf1b,Ifnar1,Klf2,Jun,Trp53i11,Cd83,Slc48a1,Xkr8,Cd200,Tulp3,Atp11a,Cd180,Mul1,P2ry14,Sell |
| 3.372e-02 | -3.39 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_UP | 172 | 21 | 15632 | 1249 |
Ogfr,Tiparp,Gsdmd,Dhrs9,Fgl2,Tbc1d1,Pde1b,Timeless,Cd74,Cd180,Fabp3,Fam111a,Evl,Prrg4,Rac3,Atp2b4,Stard7,Mdfic,Me1,Dek,Gclc |
| 3.372e-02 | -3.39 | ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | MSigDB lists | ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | 172 | 21 | 15632 | 1249 |
Cd200,Endod1,Ddx60,Evl,Mcm10,Il2rg,Tpx2,Itga9,Pttg1,Plagl1,Cd34,Ciita,Mdfic,Cd38,Tnfrsf14,Gypc,Daam1,Stap1,Abcb1a,Cd69,Rsad2 |
| 3.372e-02 | -3.39 | GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_UP | 172 | 21 | 15632 | 1249 |
Stard7,Dusp16,Cdkn1a,Osbpl3,Rbms1,Cd14,Rcan1,Tgfbi,Ciapin1,Sass6,Mthfd2,Smc5,Uchl1,Taf4b,Eef1e1,Hap1,Gclm,Ppp4r2,Pdlim7,Cx3cr1,Plekha5 |
| 3.372e-02 | -3.39 | GSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_DN | MSigDB lists | GSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_DN | 172 | 21 | 15632 | 1249 |
Irgq,Procr,Oaf,Map4k4,Txnrd1,Mthfd1l,Mgat1,Cenpj,Sco1,Otud1,Slc16a1,Kitl,Prkx,Elmod2,Rnd3,Zfp319,Fam53c,Ptprj,Usp31,Cxcl10,Ptgs2 |
| 3.374e-02 | -3.39 | Metabolism of carbohydrates | REACTOME pathways | R-MMU-71387 | 271 | 33 | 8608 | 757 |
Agrn,Gbe1,Pgm1,Ext1,Eno1,B4galt4,Dse,Abcc5,Ranbp2,Pgk1,Sdc1,Slc25a12,Vcan,Hk3,Hk2,Gpc1,Sdc2,Slc2a1,Sdc4,Gys1,Tpi1,Eno2,St3gal6,St3gal3,Ust,St3gal1,Papss2,Pcx,Slc9a1,Pfkl,Chst11,Hk1,Pfkfb3 |
| 3.376e-02 | -3.39 | endoderm development | biological process | GO:0007492 | 66 | 9 | 20694 | 1406 |
Inhba,Hhex,Notch1,Hdac1,Ankrd17,Angpt1,Itga5,Itgav,Ext1 |
| 3.376e-02 | -3.39 | circadian regulation of gene expression | biological process | GO:0032922 | 66 | 9 | 20694 | 1406 |
Ahr,Egr1,Nampt,Pml,Relb,Sirt1,Gfpt1,Noct,Hdac1 |
| 3.378e-02 | -3.39 | organic acid metabolic process | biological process | GO:0006082 | 841 | 71 | 20694 | 1406 |
Edn1,Wars,Pfkl,Prkar2b,Il15,Hk1,Papss2,Carmil1,P4ha1,Tha1,Plod3,Gclm,Lipg,Nr1h3,Dhrs9,Gclc,Kmo,Cd74,Plod2,C3,Gfpt1,Syk,Hdc,Mecp2,Pdpn,Egln3,Stat5a,Psat1,Angpt1,Me1,Rars,Mthfd2,Dse,Asah2,Gch1,Pla2g4a,Eno2,Lipe,Il4i1,Cemip2,Acod1,Hk2,Sphk1,Tlr2,Nr4a3,Adhfe1,Ptges,Pcx,Chst11,Pgk1,Mthfd1l,Hk3,Il1b,Acsl5,Txnrd1,Arg2,Hif1a,Acsl1,Mthfr,Ero1l,P4ha2,Phgdh,Nos2,Ptgs2,Phyh,Ldha,Asns,Aoah,Ass1,Tpi1,Odc1 |
| 3.388e-02 | -3.38 | GO_REGULATION_OF_RNA_STABILITY | MSigDB lists | GO_REGULATION_OF_RNA_STABILITY | 132 | 17 | 15632 | 1249 |
Psma6,Dcp1a,Psme2,Zfp36,Carhsp1,Psmd10,Psmb9,Psmb8,Tnfrsf1b,Myd88,Dcp2,Psmb10,Xrn1,Psme1,Psmb6,Mapkapk2,Zc3h12a |
| 3.395e-02 | -3.38 | GO_NEGATIVE_REGULATION_OF_TISSUE_REMODELING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TISSUE_REMODELING | 16 | 4 | 15632 | 1249 |
Abr,Tnfaip3,Cd38,Ubash3b |
| 3.395e-02 | -3.38 | GO_NEGATIVE_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 16 | 4 | 15632 | 1249 |
Ptpn2,Prnp,Ezr,Ptprj |
| 3.395e-02 | -3.38 | GO_REGULATION_OF_INTERLEUKIN_6_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_INTERLEUKIN_6_BIOSYNTHETIC_PROCESS | 16 | 4 | 15632 | 1249 |
Il1b,Ptafr,Tlr1,Tlr6 |
| 3.395e-02 | -3.38 | GO_GTP_DEPENDENT_PROTEIN_BINDING | MSigDB lists | GO_GTP_DEPENDENT_PROTEIN_BINDING | 16 | 4 | 15632 | 1249 |
Gch1,Rapgef5,Rab32,Ap3b1 |
| 3.395e-02 | -3.38 | GO_INTESTINAL_EPITHELIAL_CELL_DIFFERENTIATION | MSigDB lists | GO_INTESTINAL_EPITHELIAL_CELL_DIFFERENTIATION | 16 | 4 | 15632 | 1249 |
Prdm1,Sav1,Hif1a,Cdkn1a |
| 3.395e-02 | -3.38 | GO_NEGATIVE_REGULATION_OF_HISTONE_METHYLATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_HISTONE_METHYLATION | 16 | 4 | 15632 | 1249 |
Mecp2,Kdm4a,Bcor,Jarid2 |
| 3.395e-02 | -3.38 | GO_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS | MSigDB lists | GO_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS | 16 | 4 | 15632 | 1249 |
Notch1,Met,Thbs1,Kdr |
| 3.395e-02 | -3.38 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_UP | 16 | 4 | 15632 | 1249 |
Arrdc4,Tfec,Irak2,Dusp5 |
| 3.395e-02 | -3.38 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | MSigDB lists | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | 16 | 4 | 15632 | 1249 |
H2-Q6,H2-Q7,H2-Q4,Lnpep |
| 3.395e-02 | -3.38 | GO_REGULATION_OF_PLATELET_AGGREGATION | MSigDB lists | GO_REGULATION_OF_PLATELET_AGGREGATION | 16 | 4 | 15632 | 1249 |
Ubash3b,Lyn,Adrb2,Syk |
| 3.395e-02 | -3.38 | GO_POSITIVE_REGULATION_OF_ACTIN_CYTOSKELETON_REORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ACTIN_CYTOSKELETON_REORGANIZATION | 16 | 4 | 15632 | 1249 |
Stap1,Hcls1,Csf3,Hck |
| 3.395e-02 | -3.38 | GO_POSITIVE_REGULATION_OF_DNA_RECOMBINATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_DNA_RECOMBINATION | 16 | 4 | 15632 | 1249 |
Cd40,Tnfsf4,Prdm9,Clcf1 |
| 3.395e-02 | -3.38 | REACTOME_REGULATION_OF_KIT_SIGNALING | MSigDB lists | REACTOME_REGULATION_OF_KIT_SIGNALING | 16 | 4 | 15632 | 1249 |
Src,Kitl,Socs1,Lyn |
| 3.395e-02 | -3.38 | GO_GLYCOLIPID_BINDING | MSigDB lists | GO_GLYCOLIPID_BINDING | 16 | 4 | 15632 | 1249 |
Mppe1,Sell,Hspa2,Lyn |
| 3.395e-02 | -3.38 | GO_GTP_RHO_BINDING | MSigDB lists | GO_GTP_RHO_BINDING | 16 | 4 | 15632 | 1249 |
Triobp,Cdc42ep4,Whamm,Cdc42ep2 |
| 3.395e-02 | -3.38 | GO_REGULATION_OF_EARLY_ENDOSOME_TO_LATE_ENDOSOME_TRANSPORT | MSigDB lists | GO_REGULATION_OF_EARLY_ENDOSOME_TO_LATE_ENDOSOME_TRANSPORT | 16 | 4 | 15632 | 1249 |
Map2k1,Rab21,Ezr,Src |
| 3.395e-02 | -3.38 | GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS | 16 | 4 | 15632 | 1249 |
Ccl5,Fas,Il10,Nfkbid |
| 3.395e-02 | -3.38 | GO_CELLULAR_RESPONSE_TO_VITAMIN_D | MSigDB lists | GO_CELLULAR_RESPONSE_TO_VITAMIN_D | 16 | 4 | 15632 | 1249 |
Pim1,Fzd1,Il15,Tnc |
| 3.395e-02 | -3.38 | GO_DEATH_RECEPTOR_BINDING | MSigDB lists | GO_DEATH_RECEPTOR_BINDING | 16 | 4 | 15632 | 1249 |
Casp8,Cflar,Myd88,Casp3 |
| 3.395e-02 | -3.38 | GO_NEGATIVE_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS | 16 | 4 | 15632 | 1249 |
Pid1,Tspo,Stat3,Ddit4 |
| 3.395e-02 | -3.38 | GO_RETINA_VASCULATURE_DEVELOPMENT_IN_CAMERA_TYPE_EYE | MSigDB lists | GO_RETINA_VASCULATURE_DEVELOPMENT_IN_CAMERA_TYPE_EYE | 16 | 4 | 15632 | 1249 |
Clic4,Hif1a,Pdgfrb,Acvrl1 |
| 3.395e-02 | -3.38 | GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_DN | MSigDB lists | GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_DN | 162 | 20 | 15632 | 1249 |
Osbpl3,Cflar,Tax1bp1,Fbxo4,Tnfaip3,Lrrc8c,Irf1,Mppe1,Icam1,Lyn,Tapbpl,Akt3,Bbx,Dusp2,Kdm5b,Ap3b1,Rap1gap2,Adora2a,Ifit2,Gna15 |
| 3.396e-02 | -3.38 | SH2DOMAIN | prints domains | PR00401 | 70 | 9 | 5821 | 374 |
Cish,Nck1,Fgr,Hck,Crkl,Syk,Sla,Lyn,Src |
| 3.397e-02 | -3.38 | GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING | 308 | 34 | 15632 | 1249 |
Nfkb2,Irf1,Mafg,Nr4a3,Plscr1,Maff,Pou2f2,Etv6,Junb,Nfkb1,Rel,Fosb,Batf,Pbx1,Etv5,Plagl2,Irf2,Atf3,Egr1,Csrnp1,Plagl1,Hif1a,Irf4,Stat3,Nr3c1,Egr2,Myc,Mafk,Cebpd,Nr4a1,Fos,Tcf4,Hmga1,Jun |
| 3.399e-02 | -3.38 | ETS_Q4 | MSigDB lists | ETS_Q4 | 234 | 27 | 15632 | 1249 |
Ccl12,Hmga1,Itpr1,Rgs14,Zfp800,Treml2,Lif,Pml,Extl2,Rbms2,Rgs3,Etv5,Junb,Lcp2,Pdgfb,Dgka,Nfkbid,Sema4c,Ptk2,Lyn,Chic2,Hcls1,Rap2c,Pcdh7,Vcam1,Acsl5,Gfi1 |
| 3.405e-02 | -3.38 | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_DN | 142 | 18 | 15632 | 1249 |
Ccl2,Sod2,Plek,Pcdh7,Cacna1d,Cxcl1,Pfkfb3,Irak3,Etv5,Plaur,Dio2,Ptgir,Ripk2,Max,Mxd1,Rab20,Ccl22,Hif1a |
| 3.405e-02 | -3.38 | GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | 142 | 18 | 15632 | 1249 |
Irs2,Hif1a,Phip,Trib3,Kat2b,Socs7,Igf1r,Pde3b,Gfpt1,Ptpn2,Atp6v1d,Ccl12,Nampt,Src,Errfi1,Rhoq,Rab10,Slc9a1 |
| 3.405e-02 | -3.38 | GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_UP | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_UP | 142 | 18 | 15632 | 1249 |
Card6,Cnn2,Gpr18,Dse,Stard5,Il18rap,Ube2e2,Dyrk2,Hmgcs1,Sell,Mpp7,Ddx58,Klf8,Calcrl,Rras2,Gbp2,Slfn5,Tnfrsf14 |
| 3.405e-02 | -3.38 | GO_POSITIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION | 142 | 18 | 15632 | 1249 |
Rhou,Bnip3,Micall2,Fzd5,Casp8,Bcl2l11,Rnf31,Ddhd1,Fam162a,Plaur,Stard7,Plagl2,Kdr,Tnfsf10,Hif1a,Mul1,Adrb2,Mmp9 |
| 3.407e-02 | -3.38 | GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_UP | 152 | 19 | 15632 | 1249 |
Cd83,Chd9,Il1b,Hck,Ier2,Nfkbiz,Egr1,Rnf139,Trib1,Irs2,Ccdc86,St3gal5,Tnfsf8,Rap1gap2,Slc12a9,Dusp1,Parp8,Klf2,Jun |
| 3.407e-02 | -3.38 | GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | 152 | 19 | 15632 | 1249 |
Aim2,Hlx,Kif5c,Cdkn2d,Znrf1,Sh3bgrl2,Irak2,Clic4,Rcl1,Cdkn1a,Gbp2,Hivep2,Myadm,Clmp,Asns,Jun,Procr,Tifa,Pde5a |
| 3.416e-02 | -3.38 | beta-catenin-TCF complex | cellular component | GO:1990907 | 11 | 3 | 20747 | 1409 |
Tcf4,Tle3,Bcl9 |
| 3.420e-02 | -3.38 | artery smooth muscle contraction | biological process | GO:0014824 | 11 | 3 | 20694 | 1406 |
Edn1,Htr2a,Cd38 |
| 3.420e-02 | -3.38 | Golgi inheritance | biological process | GO:0048313 | 11 | 3 | 20694 | 1406 |
Vcpip1,Map2k1,Plk3 |
| 3.420e-02 | -3.38 | sphingolipid mediated signaling pathway | biological process | GO:0090520 | 11 | 3 | 20694 | 1406 |
Sphk1,Ezr,S1pr2 |
| 3.420e-02 | -3.38 | regulation of pinocytosis | biological process | GO:0048548 | 11 | 3 | 20694 | 1406 |
Cav1,Axl,Nr1h3 |
| 3.420e-02 | -3.38 | peptidyl-proline hydroxylation | biological process | GO:0019511 | 11 | 3 | 20694 | 1406 |
P4ha1,Egln3,P4ha2 |
| 3.420e-02 | -3.38 | negative regulation of activated T cell proliferation | biological process | GO:0046007 | 11 | 3 | 20694 | 1406 |
Casp3,Prnp,Cd274 |
| 3.420e-02 | -3.38 | common myeloid progenitor cell proliferation | biological process | GO:0035726 | 11 | 3 | 20694 | 1406 |
Fbxo4,Nr4a3,Samd9l |
| 3.420e-02 | -3.38 | positive regulation of protein homooligomerization | biological process | GO:0032464 | 11 | 3 | 20694 | 1406 |
Rhoc,Fas,Bcl2l11 |
| 3.420e-02 | -3.38 | axonal transport of mitochondrion | biological process | GO:0019896 | 11 | 3 | 20694 | 1406 |
Uchl1,Hap1,Hif1a |
| 3.420e-02 | -3.38 | left/right axis specification | biological process | GO:0070986 | 11 | 3 | 20694 | 1406 |
Cited2,Notch2,Notch1 |
| 3.420e-02 | -3.38 | response to insecticide | biological process | GO:0017085 | 11 | 3 | 20694 | 1406 |
Scn1b,Zc3h12a,Daxx |
| 3.420e-02 | -3.38 | positive regulation of neuroinflammatory response | biological process | GO:0150078 | 11 | 3 | 20694 | 1406 |
Stap1,Nupr1,Ctsc |
| 3.420e-02 | -3.38 | post-embryonic camera-type eye development | biological process | GO:0031077 | 11 | 3 | 20694 | 1406 |
Kdr,Flt1,Fzd5 |
| 3.420e-02 | -3.38 | positive regulation of histone H3-K9 methylation | biological process | GO:0051574 | 11 | 3 | 20694 | 1406 |
Sirt1,Mecp2,Jarid2 |
| 3.420e-02 | -3.38 | regulation of cardiac epithelial to mesenchymal transition | biological process | GO:0062042 | 11 | 3 | 20694 | 1406 |
Jag1,Notch1,Acvr1 |
| 3.420e-02 | -3.38 | regulation of interferon-beta biosynthetic process | biological process | GO:0045357 | 11 | 3 | 20694 | 1406 |
Nmi,Tlr3,Tlr9 |
| 3.420e-02 | -3.38 | liver regeneration | biological process | GO:0097421 | 11 | 3 | 20694 | 1406 |
Hmox1,Itpr1,Ccnd1 |
| 3.420e-02 | -3.38 | glomerulus morphogenesis | biological process | GO:0072102 | 11 | 3 | 20694 | 1406 |
Notch2,Pdgfrb,Ahr |
| 3.420e-02 | -3.38 | membrane fission | biological process | GO:0090148 | 11 | 3 | 20694 | 1406 |
Chmp4b,Mx1,Mx2 |
| 3.420e-02 | -3.38 | post-embryonic animal organ morphogenesis | biological process | GO:0048563 | 11 | 3 | 20694 | 1406 |
Bcl2l11,Kdr,Flt1 |
| 3.420e-02 | -3.38 | cellular response to nitric oxide | biological process | GO:0071732 | 11 | 3 | 20694 | 1406 |
Traf2,Cflar,Thbs1 |
| 3.420e-02 | -3.38 | organelle inheritance | biological process | GO:0048308 | 11 | 3 | 20694 | 1406 |
Map2k1,Plk3,Vcpip1 |
| 3.420e-02 | -3.38 | glucose catabolic process | biological process | GO:0006007 | 11 | 3 | 20694 | 1406 |
Pfkl,Hk1,Ldha |
| 3.420e-02 | -3.38 | collagen-activated tyrosine kinase receptor signaling pathway | biological process | GO:0038063 | 11 | 3 | 20694 | 1406 |
Syk,Ubash3b,Col4a2 |
| 3.420e-02 | -3.38 | angiotensin-activated signaling pathway | biological process | GO:0038166 | 11 | 3 | 20694 | 1406 |
Src,Agtrap,Cav1 |
| 3.433e-02 | -3.37 | CHOI_ATL_ACUTE_STAGE | MSigDB lists | CHOI_ATL_ACUTE_STAGE | 4 | 2 | 15632 | 1249 |
Met,Lhx2 |
| 3.433e-02 | -3.37 | BIERIE_INFLAMMATORY_RESPONSE_TGFB1 | MSigDB lists | BIERIE_INFLAMMATORY_RESPONSE_TGFB1 | 4 | 2 | 15632 | 1249 |
Ptgs2,Myc |
| 3.433e-02 | -3.37 | CHENG_TAF7L_TARGETS | MSigDB lists | CHENG_TAF7L_TARGETS | 4 | 2 | 15632 | 1249 |
Fscn1,D1Ertd622e |
| 3.433e-02 | -3.37 | MAINA_HYPOXIA_VHL_TARGETS_UP | MSigDB lists | MAINA_HYPOXIA_VHL_TARGETS_UP | 4 | 2 | 15632 | 1249 |
Serpine1,Slc16a3 |
| 3.433e-02 | -3.37 | FUJIWARA_PARK2_IN_LIVER_CANCER_DN | MSigDB lists | FUJIWARA_PARK2_IN_LIVER_CANCER_DN | 4 | 2 | 15632 | 1249 |
Asns,Bcl6 |
| 3.434e-02 | -3.37 | peptidyl-serine modification | biological process | GO:0018209 | 202 | 21 | 20694 | 1406 |
Src,Dyrk2,Plk2,Prkx,Pdk3,Tlk2,Morc3,Akt3,Mark2,Mapkapk2,Sgk3,Vrk2,Atm,Pdgfb,Nek6,Syk,Ikbke,Prkce,Cdk5r1,Hk1,Rictor |
| 3.434e-02 | -3.37 | regulation of blood pressure | biological process | GO:0008217 | 202 | 21 | 20694 | 1406 |
Sod2,Ahr,Nos2,Ptgs2,Hmox1,Mecp2,Pdgfb,Vegfc,F11r,Edn1,Gja1,Nox1,Ptafr,Nampt,Gch1,Adrb2,Cd34,Agtrap,Acvrl1,Ednrb,Ier3 |
| 3.434e-02 | -3.37 | presynaptic active zone membrane | cellular component | GO:0048787 | 46 | 7 | 20747 | 1409 |
Apba1,P2ry2,Atp2b4,Stx11,Stxbp1,Cacna1d,Ntng2 |
| 3.437e-02 | -3.37 | GO_NUCLEAR_BODY | MSigDB lists | GO_NUCLEAR_BODY | 319 | 35 | 15632 | 1249 |
Mdm2,Top3a,Tgs1,Rgs14,Ifi209,Ifi205,Morc3,Ifi213,N4bp1,Sqstm1,Sp140,Ifi207,Daxx,Prpf4,Ciita,Rnf34,Hinfp,Hif1a,Ifi214,Nxf1,Pml,Nek6,Sirt1,Ifi203,Isg20,Ifi211,Ep400,Ifi208,Mndal,Gfi1,Ikbke,Ifi204,Mtdh,Max,Smc5 |
| 3.439e-02 | -3.37 | KEGG_GAP_JUNCTION | MSigDB lists | KEGG_GAP_JUNCTION | 84 | 12 | 15632 | 1249 |
Itpr1,Lpar1,Map2k1,Pdgfrb,Src,Tuba4a,Gja1,Pdgfc,Htr2b,Pdgfb,Htr2a,Prkx |
| 3.439e-02 | -3.37 | GO_POSITIVE_REGULATION_OF_PROTEIN_POLYMERIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_POLYMERIZATION | 84 | 12 | 15632 | 1249 |
Cav1,Icam1,Cdc42ep4,Spire1,Nck1,Evl,Csf3,Rictor,Vasp,Hck,Prkce,Cdc42ep2 |
| 3.440e-02 | -3.37 | mesenchyme development | biological process | GO:0060485 | 214 | 22 | 20694 | 1406 |
Ednrb,Acvrl1,Thbs1,Nrp2,Sema3c,Itga4,Mdm2,Notch1,Bmp2,Acvr1,Plaur,Sema4a,Trip10,Hif1a,Sema4c,Htr2b,Gja1,Edn1,Cited2,Phactr4,Jag1,Kitl |
| 3.441e-02 | -3.37 | membrane depolarization | biological process | GO:0051899 | 46 | 7 | 20694 | 1406 |
Cacna1d,Jun,Cav1,Scn1b,Casp1,Edn1,Adora2a |
| 3.441e-02 | -3.37 | response to amino acid starvation | biological process | GO:1990928 | 46 | 7 | 20694 | 1406 |
Larp1,Sesn3,Cdkn1a,Atf3,Eif2ak2,Fas,Wdr59 |
| 3.441e-02 | -3.37 | cellular biogenic amine metabolic process | biological process | GO:0006576 | 46 | 7 | 20694 | 1406 |
Mecp2,Smox,Hdc,Sat1,Kmo,Srm,Odc1 |
| 3.441e-02 | -3.37 | negative regulation of cellular carbohydrate metabolic process | biological process | GO:0010677 | 46 | 7 | 20694 | 1406 |
Il6,Ier3,Plek,Stat3,Gfpt1,Ddit4,Nupr1 |
| 3.441e-02 | -3.37 | regulation of membrane depolarization | biological process | GO:0003254 | 46 | 7 | 20694 | 1406 |
Gja1,Kdr,Src,Scn1b,Gclm,Gclc,Tspo |
| 3.444e-02 | -3.37 | HALLMARK_PI3K_AKT_MTOR_SIGNALING | MSigDB lists | HALLMARK_PI3K_AKT_MTOR_SIGNALING | 103 | 14 | 15632 | 1249 |
Sla,Ppp2r1b,Nod1,Myd88,Cdkn1a,Nck1,Il2rg,Pikfyve,Trib3,Stat2,Nfkbib,Sqstm1,Slc2a1,Traf2 |
| 3.444e-02 | -3.37 | KIM_WT1_TARGETS_8HR_DN | MSigDB lists | KIM_WT1_TARGETS_8HR_DN | 103 | 14 | 15632 | 1249 |
Lox,Il18,Hmgcs1,Sema3c,Plk2,Msr1,Ogfr,Cited2,Plac8,Casp1,Sod2,Mid1,Ppfia3,Cp |
| 3.449e-02 | -3.37 | regulation of histone modification | biological process | GO:0031056 | 155 | 17 | 20694 | 1406 |
Jarid2,Gfi1,Mllt6,Pml,Arid5a,Bcl6,Sirt1,Kat2b,Jdp2,Daxx,Nsd3,Kdm4a,Lif,Mecp2,Atm,Mthfr,Bcor |
| 3.453e-02 | -3.37 | regulation of lipid catabolic process | biological process | GO:0050994 | 56 | 8 | 20694 | 1406 |
Pde3b,Acsl5,Irs2,Prkce,Hcar2,Il1b,Ldlr,Tnf |
| 3.453e-02 | -3.37 | purine nucleoside diphosphate metabolic process | biological process | GO:0009135 | 56 | 8 | 20694 | 1406 |
Pfkl,Hk2,Tpi1,Eno2,Pgk1,Hk1,Hk3,Ampd3 |
| 3.453e-02 | -3.37 | purine ribonucleoside diphosphate metabolic process | biological process | GO:0009179 | 56 | 8 | 20694 | 1406 |
Hk3,Pfkl,Hk2,Ampd3,Hk1,Eno2,Tpi1,Pgk1 |
| 3.453e-02 | -3.37 | dendritic tree | cellular component | GO:0097447 | 697 | 60 | 20747 | 1409 |
Nqo1,Htr2a,Cnn3,Kif3c,Pdgfb,Grk3,Map2k1,Nr3c1,Fcgr2b,Ccl2,Igsf9,Lrp8,Sipa1l1,Stau1,Map2k4,Cdk5r1,Adrb2,Lpar1,Ctla2a,Psd,Kif5c,Homer1,Fscn1,Glrx,Apba1,Lrp4,Cpeb4,Cx3cr1,Rgs14,Stat1,Bnip3,Cyfip1,Ptch1,Ptk2,Htr2b,Mark2,Rab3ip,Plk3,Pde4b,Arf4,Prnp,Xrn1,Plk2,Prkar2b,Hdc,Dbnl,Adora2a,Ift57,Cacna1d,Hap1,Nlgn2,Max,Met,Fas,Dock10,Itpr1,Txn1,Kcnj2,Ero1l,Acvrl1 |
| 3.464e-02 | -3.36 | Microglia Pathogen Phagocytosis Pathway | WikiPathways | WP3626 | 41 | 9 | 4813 | 540 |
Siglece,Syk,Trem1,Pik3cd,Rac3,Lyn,Hck,Pik3r6,Fcgr1 |
| 3.468e-02 | -3.36 | AAAYWAACM_HFH4_01 | MSigDB lists | AAAYWAACM_HFH4_01 | 224 | 26 | 15632 | 1249 |
Vasn,Maff,Fosb,Zhx2,Tfec,Gpr85,Nr4a3,Ncoa5,Hspa2,Irf4,Egr2,Slc44a1,Stap1,Bcl6,Tcf4,Dusp1,Klf3,Flrt3,Crim1,Klf7,Tle3,Pbx1,Pgm1,Prdm1,Evl,Bcor |
| 3.471e-02 | -3.36 | cellular component biogenesis | biological process | GO:0044085 | 2416 | 186 | 20694 | 1406 |
Ehd1,Cenpe,Mcoln2,Intu,Asf1a,Pkp4,Tap2,Fas,Carmil1,Nod2,Trim21,Homer1,Trip13,Rhoc,Nectin2,Tmod3,Tifa,Lrp4,Irgm2,Traf2,Rilpl1,Tapbpl,Rrs1,Micall2,Myo1b,Rnd3,Hmox1,Tlr2,Sbds,Mx2,Mx1,Vcpip1,Chmp4b,Zc3h12a,Mdn1,Daxx,Snx2,Sod2,Tcf4,Fcho2,Stxbp1,Tpx2,Rasgrp1,Ago3,Acpp,Zyx,Ciapin1,Pml,Rab20,Ikzf1,Noct,Angpt1,Pstpip2,Ccl5,Jmjd6,Cutc,Dync1h1,Nlgn2,Psip1,Pfkl,Igf1r,Cd74,Malt1,Gsdmd,Fscn1,Rpgrip1l,Max,Cox18,Cyfip1,Isg20,Whamm,Coa5,Rapgef2,Spire1,Cav1,Itpr1,Riox2,Dbnl,Sqstm1,Rab32,Kctd12,Txnrd1,Sirt1,Mmp9,Slc2a1,Csrp1,Rhou,Hopx,Pnpt1,Cenpj,Mecp2,Sco1,Birc3,Ezr,Noc4l,Evl,Arrdc4,Pf4,Apaf1,Nupr1,Triobp,Ntng2,Birc2,Rhoq,Dgkh,S1pr2,Rac3,Rab3ip,Ptk2,Fzd5,Plagl2,Pdgfrb,Gpc1,Wdr43,Ikbke,Lpar1,Kcna3,Marcks,Dst,Pdgfb,Tapbp,Hcls1,Map2k1,Kcnj2,Lcn2,Snx10,Src,Sass6,Cox17,Mpp7,Adar,Ripk3,Cycs,Flrt3,Nlrc4,Hat1,Crkl,Nlrp3,Pdss1,Mcm6,Swap70,Apba1,Optn,Abcc4,Atp6v1d,Cx3cl1,P2ry12,Gfpt1,Gch1,Denr,Spata13,Pikfyve,Irgm1,Rcl1,Nck1,H3f3b,Fnbp1l,Me1,Ift57,Stxbp3,Tmem67,Brd2,Agrn,Rnd1,Plod3,Ttc39c,Lox,Vasp,Cflar,G3bp2,Itga5,Samhd1,Prnp,Prdm9,Cd34,Psmd10,Keap1,Dnaaf3,Itgav,Gja1,Rhof,Diaph2,Pdgfc,Mlkl,Mdm2,Lrrc8c |
| 3.473e-02 | -3.36 | Ets_dom | interpro domains | IPR000418 | 26 | 5 | 19984 | 1430 |
Spic,Ets2,Etv6,Etv5,Etv3 |
| 3.476e-02 | -3.36 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP | 193 | 23 | 15632 | 1249 |
Il4i1,Ccnd1,Triobp,Dync1h1,Znfx1,Swap70,Ciita,Rab3ip,Mcmbp,Cd74,Akt3,Cnn3,Ampd3,Dcp1a,Stip1,Il1b,Dnajb2,Sec24b,Etnk1,Oasl1,Acvr1b,Adrb2,Lyn |
| 3.482e-02 | -3.36 | TPR_8 | pfam domains | PF13181 | 53 | 8 | 18711 | 1348 |
Ifit3b,Stip1,Gpsm2,Ifit3,Ifit1bl1,Tmtc2,Tomm70a,Ifit1 |
| 3.482e-02 | -3.36 | GR_Q6_01 | MSigDB lists | GR_Q6_01 | 245 | 28 | 15632 | 1249 |
B3gnt5,Mmp14,Casz1,Tet2,Slc7a11,Klf3,Parp8,Me1,Rnd1,Arg2,Sdc1,Sgms2,Prrg4,Apba1,Prdm1,Etv6,Ppp2r3a,Nrp2,Pdgfb,Caml,Vezt,Dcun1d3,Sesn3,Eif4g2,Lox,Cdc42ep4,Rcn1,Sema4c |
| 3.483e-02 | -3.36 | protein homooligomerization | biological process | GO:0051260 | 362 | 34 | 20694 | 1406 |
Pfkl,Itpr1,Nlrc4,Cav1,Cycs,Jmjd6,Hmox1,Fas,Ripk3,Mlkl,Optn,Gsdmd,Kctd12,Chmp4b,G3bp2,Traf2,Gfpt1,Marcks,Sod2,Vasp,Tifa,Kcna3,Ehd1,Ikbke,Pnpt1,Evl,Apaf1,Prnp,Angpt1,Kcnj2,Lcn2,Samhd1,Gch1,Acpp |
| 3.492e-02 | -3.35 | Atxn3 (ataxin 3) | protein interactions | 110616 | 8 | 3 | 7778 | 753 |
Itga5,Hspa1b,Dnaja1 |
| 3.492e-02 | -3.35 | Ntrk2 (neurotrophic tyrosine kinase, receptor, type 2) | protein interactions | 18212 | 8 | 3 | 7778 | 753 |
Cyfip1,Sqstm1,Uchl1 |
| 3.492e-02 | -3.35 | MYO19 (myosin XIX) | protein interactions | 80179 | 8 | 3 | 7778 | 753 |
Actb,Kif3c,Tmod3 |
| 3.492e-02 | -3.35 | DYNLRB1 (dynein light chain roadblock-type 1) | protein interactions | 83658 | 8 | 3 | 7778 | 753 |
Dync1h1,Cenpe,Dync1i2 |
| 3.492e-02 | -3.35 | RPL11 (ribosomal protein L11) | protein interactions | 6135 | 8 | 3 | 7778 | 753 |
Mdm2,Brwd3,Rrbp1 |
| 3.492e-02 | -3.35 | TPM3 (tropomyosin 3) | protein interactions | 7170 | 8 | 3 | 7778 | 753 |
Itga5,Actb,Tpm4 |
| 3.492e-02 | -3.35 | RPS16 (ribosomal protein S16) | protein interactions | 6217 | 8 | 3 | 7778 | 753 |
Rrbp1,Ksr1,Ktn1 |
| 3.492e-02 | -3.35 | Dmrtc2 (doublesex and mab-3 related transcription factor like family C2) | protein interactions | 71241 | 8 | 3 | 7778 | 753 |
Mcm6,Plagl2,Nr3c1 |
| 3.492e-02 | -3.35 | CEP162 (centrosomal protein 162) | protein interactions | 22832 | 8 | 3 | 7778 | 753 |
Tmod3,Vcpip1,Actb |
| 3.495e-02 | -3.35 | GO_RESPONSE_TO_AMMONIUM_ION | MSigDB lists | GO_RESPONSE_TO_AMMONIUM_ION | 48 | 8 | 15632 | 1249 |
Gna15,Ptafr,Cdk5r1,Ass1,Agrn,Ccl5,Htr2b,Plau |
| 3.495e-02 | -3.35 | REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | MSigDB lists | REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | 48 | 8 | 15632 | 1249 |
Psma6,Psme2,Psmb9,Psmd10,Psmb10,Psme1,Psmb8,Psmb6 |
| 3.495e-02 | -3.35 | GO_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | MSigDB lists | GO_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | 48 | 8 | 15632 | 1249 |
Angpt1,Acvrl1,Notch1,Vegfc,Thbs1,Pdgfb,Ptgs2,Stat5a |
| 3.495e-02 | -3.35 | GNF2_ITGAL | MSigDB lists | GNF2_ITGAL | 48 | 8 | 15632 | 1249 |
Lcp2,Arhgef3,Ddx58,Itgal,Casp8,Parp8,Rasgrp1,Dusp2 |
| 3.495e-02 | -3.35 | ZHU_CMV_8_HR_DN | MSigDB lists | ZHU_CMV_8_HR_DN | 48 | 8 | 15632 | 1249 |
Ahr,Cebpd,Igf1r,Ldlr,Ralgds,Nr3c1,Rbms1,Ddit4 |
| 3.495e-02 | -3.35 | GO_NEGATIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | 48 | 8 | 15632 | 1249 |
Serpine1,Bcl6,Src,Acvrl1,Notch1,Mmp14,Thbs1,Gcnt2 |
| 3.500e-02 | -3.35 | DANG_BOUND_BY_MYC | MSigDB lists | DANG_BOUND_BY_MYC | 1015 | 97 | 15632 | 1249 |
Nfkbib,Ociad1,Isg20,Sco1,Nfkb1,Atm,Nfil3,Ppp2r1b,Arf4,Trib1,Odc1,Egr3,Cnot4,Cept1,Pla2g4a,Ctsc,Hmga1,Srm,Syk,Sqstm1,Rbl1,Tle3,Col4a2,Vasp,Sap30,Gpr132,Serpine1,Atp6v1d,Cacybp,Fzd5,4933430I17Rik,Keap1,Rcl1,Cxcl1,Parp3,Ripk2,Hmox1,Slc31a1,Prdx5,Serp1,Plod3,Tnf,Sla,Tulp3,Ch25h,Eef1e1,Met,Sirt1,Ampd3,Lnpep,Rabgef1,Pdk3,Eno2,Birc3,Rnaset2b,Esd,Dck,Ppa1,Kpna3,Myc,Irf4,Psmd10,Slc28a2,Gclc,Ccnd2,Tyk2,Maff,Pdgfb,Rnaset2a,Junb,Jarid2,Arid4a,Txn1,Abcc4,Snapc1,Uchl1,Ldha,Dnaja2,Lztfl1,Mdm2,Cish,Fchsd2,Rbbp8,Eno1,Acpp,Ifnar1,Daxx,Cd164,Nod1,Cd180,Ddx58,Hif1a,Icam1,Mthfr,Irf2,Ier2,Nfkbil1 |
| 3.510e-02 | -3.35 | JMJC | prosite domains | PS51184 | 32 | 6 | 13278 | 1037 |
Riox2,Kdm5b,Kdm6b,Kdm4a,Jmjd6,Jarid2 |
| 3.510e-02 | -3.35 | SENESE_HDAC3_TARGETS_DN | MSigDB lists | SENESE_HDAC3_TARGETS_DN | 450 | 47 | 15632 | 1249 |
Slc7a5,Antxr1,Hsd17b12,Golga3,Asns,Clic4,Gcnt2,Gca,Snapc1,Pcdh7,Gng12,Pkp4,Mcm6,Mob3b,Rab11fip1,Carhsp1,Phgdh,Aebp2,Mecp2,Tcf4,Dse,Mdfic,Crim1,Slc39a14,Jdp2,Psat1,Plekha2,Mov10,Vezt,Rap2c,Tax1bp1,Gfpt1,Orai2,Ebi3,Endod1,Bbx,Edn1,Cxcl14,Sdc2,Tagln,Cenpe,Plac8,Gadd45b,D16Ertd472e,Egr1,Mpp7,Cyth3 |
| 3.513e-02 | -3.35 | ETS_DOMAIN_2 | prosite domains | PS00346 | 24 | 5 | 13278 | 1037 |
Etv6,Etv3,Ets2,Etv5,Spic |
| 3.520e-02 | -3.35 | phosphatidylinositol metabolic process | biological process | GO:0046488 | 121 | 14 | 20694 | 1406 |
Atm,Socs7,Pgap2,Inpp1,Cish,Socs3,Inpp5b,Socs1,Pik3cd,Pigv,Plek,Pdgfrb,Pikfyve,Mppe1 |
| 3.522e-02 | -3.35 | GSE17721_4H_VS_24H_POLYIC_BMDC_UP | MSigDB lists | GSE17721_4H_VS_24H_POLYIC_BMDC_UP | 183 | 22 | 15632 | 1249 |
Nlrp3,Pim1,Clec5a,Calcrl,Nfkbiz,Mtmr14,Tfec,Pgk1,Klf7,Traf5,Gpsm2,Plod2,Spryd7,Ccl12,Ppp1r14b,Slc4a7,Birc3,Ccnj,Met,Fgl2,Slc7a5,Minpp1 |
| 3.522e-02 | -3.35 | GSE27786_CD4_TCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_CD4_TCELL_VS_MONO_MAC_UP | 183 | 22 | 15632 | 1249 |
Lnpep,Brd2,Card6,Cysltr2,Rab10,Il12rb1,Denr,Socs3,Irf1,Cox18,Azi2,Ttc39b,Rcl1,Socs7,Ppp2r2a,Klf3,Sqstm1,Parp14,Taf4b,Rbms2,Rab3ip,Tap1 |
| 3.522e-02 | -3.35 | GSE13411_NAIVE_VS_SWITCHED_MEMORY_BCELL_DN | MSigDB lists | GSE13411_NAIVE_VS_SWITCHED_MEMORY_BCELL_DN | 183 | 22 | 15632 | 1249 |
Ccrl2,Nr3c1,Rel,H2-Q6,Daam1,Adap2,Csf3r,Slc31a2,Dync1h1,H2-Q4,Syk,Ccl5,Ppfibp2,Pgk1,Abcc1,Rbms1,Osbpl3,Chd9,Lox,Ptafr,H2-Q7,Fas |
| 3.522e-02 | -3.35 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_UP | 183 | 22 | 15632 | 1249 |
Mcoln2,Papss2,Slc25a25,Plekha5,Eif2ak2,Stat5a,Bcl6,Traf2,Slc39a4,Tbc1d1,St3gal1,Nr4a3,Kif3c,Azi2,Dnajb4,Kitl,Rbms1,Trafd1,Brwd3,Ankib1,Pde4b,Klf2 |
| 3.522e-02 | -3.35 | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_DN | MSigDB lists | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_DN | 183 | 22 | 15632 | 1249 |
Klf2,Mov10,Abcc5,Tnf,Dtnb,Cd69,Uba7,Mmp13,Vasn,Atxn7l1,Tnc,Trib1,Pttg1,Plagl1,Ptgs2,Egr3,Mcm10,Tnks1bp1,Hck,Tagap,Il15,Trp53i11 |
| 3.522e-02 | -3.35 | GSE20198_IL12_IL18_VS_IFNA_TREATED_ACT_CD4_TCELL_DN | MSigDB lists | GSE20198_IL12_IL18_VS_IFNA_TREATED_ACT_CD4_TCELL_DN | 183 | 22 | 15632 | 1249 |
Dck,Usp25,Ccnd2,Rras2,Cd34,Ppp2r1b,Cd164,Il15ra,Relb,Ehd1,Fam43a,Gpr18,Cenpj,Hdc,Rab10,Stat3,Stap1,Snx2,Stat4,Treml2,Rnf19a,Tdrd7 |
| 3.522e-02 | -3.35 | GSE20727_CTRL_VS_DNFB_ALLERGEN_TREATED_DC_UP | MSigDB lists | GSE20727_CTRL_VS_DNFB_ALLERGEN_TREATED_DC_UP | 183 | 22 | 15632 | 1249 |
Gna15,Fam72a,Car13,Mafg,Tmod3,Ldha,Nfil3,Prkx,Ccl4,Gfpt1,Ttc39c,Cx3cr1,Cpd,Gsr,Carhsp1,Irf4,Fgr,Nmral1,Lrp8,Abr,Dusp14,Cd80 |
| 3.522e-02 | -3.35 | GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_UP | MSigDB lists | GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_UP | 183 | 22 | 15632 | 1249 |
Wars,Slc39a14,Hk2,Trip13,Noc4l,Plek,Pdk3,Rcl1,Wdr43,Slc43a3,Mthfd2,Pim2,Stap1,Tpst1,Rbbp8,Plac8,Ripk3,Ahsa1,Ccnd2,Psmb10,Gmppb,St3gal6 |
| 3.522e-02 | -3.35 | GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_DN | 183 | 22 | 15632 | 1249 |
Itgal,Zfp36,Il18rap,Dgka,Ldha,Larp1,Pik3cd,Sema4a,Adrb2,Ikbke,Wdr43,Ass1,Plac8,Klf6,Dusp1,Fos,1110038F14Rik,Fcgr2b,D1Ertd622e,Slco3a1,Sell,Gpc1 |
| 3.522e-02 | -3.35 | GSE46143_CTRL_VS_LMP2A_TRANSDUCED_CD10_POS_GC_BCELL_DN | MSigDB lists | GSE46143_CTRL_VS_LMP2A_TRANSDUCED_CD10_POS_GC_BCELL_DN | 183 | 22 | 15632 | 1249 |
Cd200,Tax1bp1,Vps54,Dusp6,Ltbp2,Caml,Phlda1,Pgm1,Nxf1,Sass6,Rhoh,Pnpt1,Arhgef3,Mgat1,Ankrd17,Ccng2,Fcgr2b,Abcb1a,Dbnl,Dusp8,Nat2,Rhoq |
| 3.522e-02 | -3.35 | GSE7852_LN_VS_FAT_TREG_UP | MSigDB lists | GSE7852_LN_VS_FAT_TREG_UP | 183 | 22 | 15632 | 1249 |
Aida,Traf3ip2,Ptger4,Stard7,Zc3h12c,Sesn3,Dcp1a,Caml,Rnf135,Phip,Ahr,Mcmbp,Ifit1,1600014C10Rik,Sgk3,Arhgef3,Ctu1,Gypc,Trmt1l,Cnn2,Ccng2,Bbx |
| 3.522e-02 | -3.35 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN | 183 | 22 | 15632 | 1249 |
Slc39a14,Timeless,Trip13,Phlda1,Csf1,Med21,Dusp6,Nfil3,Mthfd2,Trib3,Cd200,Etnk1,Rab11fip1,Ggct,Gpsm2,Eno1,Tspan3,Aoah,Gmppb,Pttg1,Palld,Egr1 |
| 3.525e-02 | -3.35 | AGGAAGC_MIR5163P | MSigDB lists | AGGAAGC_MIR5163P | 113 | 15 | 15632 | 1249 |
Herc6,Dusp5,Lif,Col18a1,Nxf1,Smg7,Spred1,Ifit1bl1,Ifit1bl2,Mtus1,Rilpl1,Stat4,Vasn,Glipr2,Vasp |
| 3.544e-02 | -3.34 | MAPK family signaling cascades | REACTOME pathways | R-MMU-5683057 | 243 | 30 | 8608 | 757 |
Pdgfrb,Il2rg,Ksr1,Map2k1,Cdc42ep2,Jak2,Ppp2r1b,Pdgfb,Kitl,Spred1,Irs2,Ppp2r5a,Src,Il6,Psme2b,Angpt1,Psmb9,Rasgrp1,Rapgef2,Dusp6,Psmb6,Dusp5,Psme1,Psmb8,Ptk2,Met,Psmb10,Psma6,Psme2,Psmd10 |
| 3.557e-02 | -3.34 | Degradation of beta-catenin by the destruction complex | REACTOME pathways | R-MMU-195253 | 77 | 12 | 8608 | 757 |
Tle3,Psmb9,Psmb8,Psmb10,Psma6,Ppp2r5a,Psme2,Psmb6,Psme2b,Ppp2r1b,Psme1,Psmd10 |
| 3.560e-02 | -3.34 | Sialyl_trans | interpro domains | IPR012163 | 18 | 4 | 19984 | 1430 |
St3gal5,St3gal6,St3gal3,St3gal1 |
| 3.561e-02 | -3.34 | peptide transmembrane transporter activity | molecular function | GO:1904680 | 27 | 5 | 20217 | 1400 |
Tap2,Slco3a1,Abcc1,Tap1,Slc15a3 |
| 3.561e-02 | -3.34 | GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_DN | MSigDB lists | GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_DN | 173 | 21 | 15632 | 1249 |
Plk2,Plekhf2,Dpy19l1,Dgka,Hivep3,Ccnd1,Rin2,Phlpp1,Mmd,St3gal5,D1Ertd622e,Etv3,Itga9,Irf2,Endod1,Vrk2,Frmd6,Extl2,Sgcb,Arf4,Cacna1d |
| 3.561e-02 | -3.34 | GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP | MSigDB lists | GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP | 173 | 21 | 15632 | 1249 |
H3f3b,Tap1,Sdc4,Ccl4,Sla,Aldh1b1,Il12b,Endod1,Nfkbie,Vcan,Cd69,Pou2f2,Pla2g4a,Inpp5b,Med13,Myc,Ppp2r5a,Irf8,Sik3,Tcf4,Flt1 |
| 3.561e-02 | -3.34 | LTE2_UP.V1_UP | MSigDB lists | LTE2_UP.V1_UP | 173 | 21 | 15632 | 1249 |
Rcan1,Kmo,Plagl1,Hmgcs1,Ptger4,Dram1,Lrp8,Mmp9,Ust,Lmo4,Cd302,P4ha2,Rin2,Chst11,Ppfia3,Dusp4,Gclm,Pstpip2,Edn1,Rhoq,Katna1 |
| 3.561e-02 | -3.34 | Ets | pfam domains | PF00178 | 26 | 5 | 18711 | 1348 |
Spic,Etv3,Etv6,Etv5,Ets2 |
| 3.578e-02 | -3.33 | MODULE_493 | MSigDB lists | MODULE_493 | 57 | 9 | 15632 | 1249 |
Trip10,Tcf4,Gja1,Abcc5,Dram1,Dcbld2,Pdlim7,Lpcat2,Crlf3 |
| 3.578e-02 | -3.33 | GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING | MSigDB lists | GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_BINDING | 123 | 16 | 15632 | 1249 |
Jun,Rbbp8,Med21,Cited2,Tcf4,Ahrr,Psip1,Hdac1,Med13,Spen,Nr3c1,Hif1a,Lif,Notch1,Lhx2,Notch2 |
| 3.580e-02 | -3.33 | PID_HDAC_CLASSI_PATHWAY | MSigDB lists | PID_HDAC_CLASSI_PATHWAY | 66 | 10 | 15632 | 1249 |
Hdac1,Sirt1,Sap30,Stat3,Kat2b,Nfkb1,Tnf,Nfkbia,Max,Mxd1 |
| 3.580e-02 | -3.33 | regulation of cellular response to insulin stimulus | biological process | GO:1900076 | 88 | 11 | 20694 | 1406 |
Pid1,Il1b,Nck1,Ptpn2,Sirt1,Src,Ncoa5,Sesn3,Socs1,Cish,Socs3 |
| 3.584e-02 | -3.33 | GPCR ligand binding | REACTOME pathways | R-MMU-500792 | 401 | 46 | 8608 | 757 |
Calcrl,P2ry12,S1pr2,Pf4,Cxcl10,Fpr1,Cxcl1,Cx3cr1,Cxcl3,Ptgir,Gpr68,Gng11,P2ry2,Cd55,P2ry13,Hcar2,Gnb4,Cx3cl1,Lpar1,Ccr3,P2ry14,Edn1,Adrb2,Adora2a,Htr2a,Cxcl2,Cxcl9,Ccl5,Gpr35,Prokr1,Ccl9,Adora2b,Gpr18,Fpr2,Gpr132,Htr2b,Ednrb,C3,Gng12,Ptafr,Cxcl11,Ptger4,Ccrl2,Xcr1,Cysltr2,Gng4 |
| 3.588e-02 | -3.33 | connective tissue development | biological process | GO:0061448 | 227 | 23 | 20694 | 1406 |
Csf1,Egr1,Chst11,Edn1,Itgb8,Zeb1,Hmga2,Notch1,Pdgfrb,Col27a1,Arid5b,Lox,Mmp13,Sik3,Hif1a,Slc25a25,Col11a2,Pdgfb,Arid5a,Bmp2,4932438A13Rik,Thbs1,Slc39a13 |
| 3.591e-02 | -3.33 | MORF_CASP2 | MSigDB lists | MORF_CASP2 | 94 | 13 | 15632 | 1249 |
Gpr35,Rap1gap2,Casp2,Tra2a,Cnot4,Ikbkg,Psd4,Mgat1,Sik3,Cnp,Htr2a,Pml,Mmp25 |
| 3.591e-02 | -3.33 | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP | 163 | 20 | 15632 | 1249 |
Plk2,Bcl6,Jun,4930523C07Rik,Mfap3l,Nqo1,Sap30,Il4ra,Socs1,Adrb2,Hmgcs1,Pgs1,Cd200,Klf7,Ahr,Tnfaip3,Gfpt1,Clic4,Thbs1,Tspo |
| 3.591e-02 | -3.33 | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_SAP1A_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_SAP1A_KO_DP_THYMOCYTES_UP | 163 | 20 | 15632 | 1249 |
Optn,Mmd,Samd9l,Ccng2,Rai14,Otud1,Serpine1,Tagln,Atp2b4,Snn,Trafd1,Rnd3,Gbp2b,Adam19,Cdk5r1,Pikfyve,Egr3,Ifi35,Filip1l,Uchl1 |
| 3.592e-02 | -3.33 | CD8 receptor binding | molecular function | GO:0042610 | 11 | 3 | 20217 | 1400 |
H2-Q7,H2-Q4,H2-Q6 |
| 3.592e-02 | -3.33 | beta-2-microglobulin binding | molecular function | GO:0030881 | 11 | 3 | 20217 | 1400 |
H2-Q7,H2-Q4,H2-Q6 |
| 3.592e-02 | -3.33 | phosphatase activator activity | molecular function | GO:0019211 | 11 | 3 | 20217 | 1400 |
Bmp2,Phactr4,Ppp2r5a |
| 3.592e-02 | -3.33 | protein antigen binding | molecular function | GO:1990405 | 11 | 3 | 20217 | 1400 |
H2-Ab1,Itga4,Ep400 |
| 3.592e-02 | -3.33 | phosphatidylinositol 3-kinase activity | molecular function | GO:0035004 | 11 | 3 | 20217 | 1400 |
Pik3r6,Atm,Pik3cd |
| 3.592e-02 | -3.33 | lipase activator activity | molecular function | GO:0060229 | 11 | 3 | 20217 | 1400 |
Casp3,Nsmaf,Ccl5 |
| 3.594e-02 | -3.33 | Drf_FH3 | smart domains | SM01139 | 9 | 3 | 9567 | 823 |
Fmnl2,Daam1,Diaph2 |
| 3.594e-02 | -3.33 | PDGF | smart domains | SM00141 | 9 | 3 | 9567 | 823 |
Vegfc,Pdgfb,Pdgfc |
| 3.594e-02 | -3.33 | Drf_GBD | smart domains | SM01140 | 9 | 3 | 9567 | 823 |
Diaph2,Daam1,Fmnl2 |
| 3.594e-02 | -3.33 | JmjN | smart domains | SM00545 | 9 | 3 | 9567 | 823 |
Kdm5b,Jarid2,Kdm4a |
| 3.599e-02 | -3.32 | GO_CELLULAR_RESPONSE_TO_STEROID_HORMONE_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_STEROID_HORMONE_STIMULUS | 204 | 24 | 15632 | 1249 |
Med13,Il10,Rnf14,Ccne1,Pmepa1,Jak2,Serpinb9,Nr4a3,Mdm2,Errfi1,Acvr1,Ifnb1,Nr3c1,Edn1,Il6,Dnaja1,Src,Nr4a1,Ass1,Ccl12,Daxx,Ahr,Nr1h3,Fas |
| 3.599e-02 | -3.32 | KIM_ALL_DISORDERS_CALB1_CORR_UP | MSigDB lists | KIM_ALL_DISORDERS_CALB1_CORR_UP | 506 | 52 | 15632 | 1249 |
Sec24b,Pgk1,Ppp2r2a,Stip1,Kif3c,Grina,Psmb6,Dnaja2,Uchl1,Rtn1,Spint2,G3bp2,Slc25a12,Atp6v1d,Map2k1,Asns,Plk2,Tuba4a,Brd2,Ahsa1,Psma6,Cers6,Dusp8,Itpr1,Abcc5,Dync1h1,Prkar2b,Tax1bp1,Idi1,Map2k4,Cacnb3,Cd200,Egr3,Alas1,Eno2,Dusp14,Adar,Htr2a,Cx3cl1,Prnp,Stxbp1,Abr,Optn,Bnip3,Ggct,Dnaja1,Dock4,Tspan3,Rapgef5,Ass1,Cx3cr1,Hivep2 |
| 3.607e-02 | -3.32 | GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_DN | MSigDB lists | GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_DN | 133 | 17 | 15632 | 1249 |
Il18,Cdk5r1,Larp1,Plk3,Cmpk2,Myo10,Klf7,Clic4,Adam19,Osbpl3,Pdgfrb,Klhl25,Klf2,Dhx58,Il18bp,Tmem171,Ext1 |
| 3.607e-02 | -3.32 | SCHLOSSER_SERUM_RESPONSE_UP | MSigDB lists | SCHLOSSER_SERUM_RESPONSE_UP | 133 | 17 | 15632 | 1249 |
Map4k4,Brd2,Cep350,Stat3,Ifna6,Tapbp,Pou2f2,Tyk2,Ifna5,St3gal1,Ell2,Egr1,Irf1,Il2rg,Ifna1,Orai2,Ifna2 |
| 3.607e-02 | -3.32 | GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_UP | MSigDB lists | GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_UP | 133 | 17 | 15632 | 1249 |
Card6,Klf3,Nlrc5,Tnfsf8,Myc,Rasgrp1,Treml2,Kdm5b,Sele,Bcor,Cd55,Mppe1,Ccnd2,Ikbke,Zhx2,Crim1,Rab3ip |
| 3.607e-02 | -3.32 | WHITFIELD_CELL_CYCLE_M_G1 | MSigDB lists | WHITFIELD_CELL_CYCLE_M_G1 | 133 | 17 | 15632 | 1249 |
Tle3,Ppp2r2a,Larp1,Cyth3,Pttg1,Zfp281,Hif1a,Antxr1,Mllt6,Kdm5b,Dcp1a,Ifit1bl2,Ifit1bl1,Ifit2,Gdf15,Plk2,Znfx1 |
| 3.607e-02 | -3.32 | WHITFIELD_CELL_CYCLE_S | MSigDB lists | WHITFIELD_CELL_CYCLE_S | 133 | 17 | 15632 | 1249 |
Pilrb1,Pilrb2,Kat2b,Osgin2,Phip,Dnajb4,Dmxl2,Gclm,Casp2,Cers6,Ifit1bl2,Ifit1bl1,Abcc5,Dcun1d3,Acpp,Lmo4,Rbbp8 |
| 3.610e-02 | -3.32 | GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_DN | MSigDB lists | GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_DN | 153 | 19 | 15632 | 1249 |
Dnajb2,Ccdc88b,Sec24a,1600014C10Rik,Dnajb4,Dcp2,Lpar1,Cdk5r1,Malt1,Crkl,Ube2l6,Tmeff1,Stxbp3,Lrch1,Znfx1,Serp1,Parp8,Eif4g2,P4ha1 |
| 3.610e-02 | -3.32 | GCNP_SHH_UP_EARLY.V1_DN | MSigDB lists | GCNP_SHH_UP_EARLY.V1_DN | 153 | 19 | 15632 | 1249 |
Ccrl2,Tmem176a,Caml,Pla2g4a,Pde1b,Plk2,Gbp7,Vps54,Map2k1,Cited2,Map4k4,Ccl12,Ppfibp2,Cd38,Notch1,Slc43a3,Itga4,Ier2,Egr1 |
| 3.610e-02 | -3.32 | GCM_MAP4K4 | MSigDB lists | GCM_MAP4K4 | 153 | 19 | 15632 | 1249 |
Lrp4,Sesn3,Map4k4,Dync1h1,Psat1,Sik3,Cep350,Ankrd17,Mtus1,Phlpp2,Ociad1,4932438A13Rik,Ptk2,Crkl,Spire1,Cldnd1,Myo10,Agpat4,Fmnl2 |
| 3.614e-02 | -3.32 | germ plasm | cellular component | GO:0060293 | 19 | 4 | 20747 | 1409 |
Carhsp1,Tdrd7,Ddx4,Mov10 |
| 3.614e-02 | -3.32 | pole plasm | cellular component | GO:0045495 | 19 | 4 | 20747 | 1409 |
Mov10,Carhsp1,Tdrd7,Ddx4 |
| 3.614e-02 | -3.32 | P granule | cellular component | GO:0043186 | 19 | 4 | 20747 | 1409 |
Ddx4,Carhsp1,Tdrd7,Mov10 |
| 3.614e-02 | -3.32 | platelet alpha granule | cellular component | GO:0031091 | 19 | 4 | 20747 | 1409 |
Thbs1,Stxbp1,Pf4,Stxbp3 |
| 3.616e-02 | -3.32 | CLPPROTEASEA | prints domains | PR00300 | 5 | 2 | 5821 | 374 |
Trip13,Tor3a |
| 3.616e-02 | -3.32 | INTCLCHANNEL | prints domains | PR01263 | 5 | 2 | 5821 | 374 |
Clic4,Clic5 |
| 3.616e-02 | -3.32 | ADENOSINER | prints domains | PR00424 | 5 | 2 | 5821 | 374 |
Adora2a,Adora2b |
| 3.616e-02 | -3.32 | LEUZIPPRMYC | prints domains | PR00044 | 5 | 2 | 5821 | 374 |
Myc,Mycl |
| 3.617e-02 | -3.32 | GSE27291_6H_VS_7D_STIM_GAMMADELTA_TCELL_DN | MSigDB lists | GSE27291_6H_VS_7D_STIM_GAMMADELTA_TCELL_DN | 143 | 18 | 15632 | 1249 |
Chd9,Adar,Rgs1,Nck1,Trib1,Fcgr2b,Ubtd2,Slc7a5,Mmd,Klf6,Pde4b,Rgl1,Hsd17b12,Slc7a11,Dse,Mtus1,Tcf4,Bcl6 |
| 3.617e-02 | -3.32 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_UP | 143 | 18 | 15632 | 1249 |
Pla2g4a,Nrp2,Csf1,Stat4,I830077J02Rik,Usp35,Spint2,Adhfe1,Bcl2l11,Dusp6,Timp1,Rrs1,Etv5,Cd55,Nek6,Rtn1,Ccl22,Nr1h3 |
| 3.619e-02 | -3.32 | negative regulation of astrocyte differentiation | biological process | GO:0048712 | 19 | 4 | 20694 | 1406 |
Kdm4a,Mecp2,Hmga2,Ldlr |
| 3.619e-02 | -3.32 | polyamine metabolic process | biological process | GO:0006595 | 19 | 4 | 20694 | 1406 |
Odc1,Sat1,Smox,Srm |
| 3.619e-02 | -3.32 | regulation of tolerance induction | biological process | GO:0002643 | 19 | 4 | 20694 | 1406 |
Phlpp1,Irak3,Cd86,Cd274 |
| 3.619e-02 | -3.32 | mitochondrial respiratory chain complex IV assembly | biological process | GO:0033617 | 19 | 4 | 20694 | 1406 |
Cox17,Sco1,Cox18,Coa5 |
| 3.619e-02 | -3.32 | regulation of ARF protein signal transduction | biological process | GO:0032012 | 19 | 4 | 20694 | 1406 |
Psd4,Cyth3,Map4k4,Psd |
| 3.619e-02 | -3.32 | ovulation | biological process | GO:0030728 | 19 | 4 | 20694 | 1406 |
Ptgs2,Pla2g4a,Nos2,Sirt1 |
| 3.619e-02 | -3.32 | regulation of phagocytosis, engulfment | biological process | GO:0060099 | 19 | 4 | 20694 | 1406 |
Stap1,Fcgr1,Siglece,C3 |
| 3.619e-02 | -3.32 | positive regulation of vascular associated smooth muscle cell migration | biological process | GO:1904754 | 19 | 4 | 20694 | 1406 |
Dock4,Nr4a3,Mdm2,Pdgfb |
| 3.619e-02 | -3.32 | regulation of monocyte chemotactic protein-1 production | biological process | GO:0071637 | 19 | 4 | 20694 | 1406 |
Il1a,Il1b,Nod2,Mcoln2 |
| 3.619e-02 | -3.32 | apoptotic process involved in morphogenesis | biological process | GO:0060561 | 19 | 4 | 20694 | 1406 |
Ppp2r1b,Notch1,Bcl2l11,Fzd5 |
| 3.619e-02 | -3.32 | regulation of defense response to bacterium | biological process | GO:1900424 | 19 | 4 | 20694 | 1406 |
Arg2,Mapkbp1,Nod2,Lgals9 |
| 3.619e-02 | -3.32 | regulation of transposition | biological process | GO:0010528 | 19 | 4 | 20694 | 1406 |
Apobec3,Tut7,Mov10,Ddx4 |
| 3.619e-02 | -3.32 | intrinsic apoptotic signaling pathway in response to oxidative stress | biological process | GO:0008631 | 19 | 4 | 20694 | 1406 |
Jak2,Uaca,Sod2,Pml |
| 3.619e-02 | -3.32 | negative regulation of bone mineralization | biological process | GO:0030502 | 19 | 4 | 20694 | 1406 |
Bcor,Srgn,Hif1a,Ccr1 |
| 3.619e-02 | -3.32 | NAD metabolic process | biological process | GO:0019674 | 19 | 4 | 20694 | 1406 |
Kmo,Hk1,Ldha,Pfkl |
| 3.619e-02 | -3.32 | negative regulation of transposition | biological process | GO:0010529 | 19 | 4 | 20694 | 1406 |
Apobec3,Mov10,Tut7,Ddx4 |
| 3.619e-02 | -3.32 | positive regulation of myeloid leukocyte cytokine production involved in immune response | biological process | GO:0061081 | 19 | 4 | 20694 | 1406 |
Cd74,Nr4a3,Tlr2,Ddx58 |
| 3.619e-02 | -3.32 | regulation of interleukin-13 production | biological process | GO:0032656 | 19 | 4 | 20694 | 1406 |
Irf4,Arg2,Tnfsf4,Nlrp3 |
| 3.619e-02 | -3.32 | regulation of hepatocyte proliferation | biological process | GO:2000345 | 19 | 4 | 20694 | 1406 |
Tnfaip3,Cflar,Itpr1,Plau |
| 3.623e-02 | -3.32 | C_TYPE_LECTIN_2 | prosite domains | PS50041 | 116 | 15 | 13278 | 1037 |
Clec5a,Clec4e,Clec4d,Clec4n,Olr1,Cd69,Klrk1,Sele,Sell,Layn,Clec2d,Ly75,Vcan,Cd302,Clec4a1 |
| 3.623e-02 | -3.32 | TPR_REGION | prosite domains | PS50293 | 116 | 15 | 13278 | 1037 |
Tomm70a,P4ha1,Gpsm2,P4ha2,Tmtc2,Ifit1bl1,Stip1,Ifit1,Ranbp2,Ifit1bl2,Naa25,Ifit2,Ifit3,Ttc9c,Ifit3b |
| 3.643e-02 | -3.31 | early endosome | cellular component | GO:0005769 | 264 | 26 | 20747 | 1409 |
Ldlr,Dtx3l,Stx6,Ehd1,Vcam1,Rab20,Fzd5,P2ry2,Rab32,Lipg,Pmepa1,Rab21,H2-Ab1,Map2k1,Samd9l,Wdfy1,Gja1,Pikfyve,Kdr,Nox1,Ifitm1,Rabgef1,Clcn5,Cd274,Myo1b,Sphk1 |
| 3.654e-02 | -3.31 | female gamete generation | biological process | GO:0007292 | 133 | 15 | 20694 | 1406 |
H3f3b,Tut7,Sirt1,Src,Diaph2,Pla2g4a,Etv6,Marf1,Taf4b,Atm,Trip13,Mcm9,Ptgs2,Nos2,Spire1 |
| 3.657e-02 | -3.31 | REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK | MSigDB lists | REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK | 194 | 23 | 15632 | 1249 |
Gng4,Dgkh,Ptafr,Lpar1,Fpr2,Gng11,Htr2a,Gnb4,Xcr1,Htr2b,Gng12,Ednrb,P2ry2,Map2k1,Gna15,Prkce,Prokr1,Cysltr2,Gpr132,Edn1,Dgka,Rasgrp1,Gpr68 |
| 3.664e-02 | -3.31 | GO_CELL_CELL_JUNCTION | MSigDB lists | GO_CELL_CELL_JUNCTION | 353 | 38 | 15632 | 1249 |
Zyx,Slc2a1,Cnn2,Clmp,Flrt3,Ccnd1,Kcnj2,Micall2,F11r,Ddx58,Mpp7,Pikfyve,Nck1,Fzd5,Lcp2,Flrt2,Gja1,Myadm,Rapgef2,Mmp13,Vasp,Slc9a1,Fabp7,Scn1b,Lyn,Pdzd11,Frmd4a,Ptprj,Mtdh,Itga5,Cd200,Pkp4,Frmd6,Keap1,Fscn1,Rpgrip1l,Clic4,Rap2c |
| 3.689e-02 | -3.30 | immunological synapse | cellular component | GO:0001772 | 37 | 6 | 20747 | 1409 |
Itgal,Ptprj,Rhoh,Icam1,Scimp,Ezr |
| 3.689e-02 | -3.30 | postsynaptic specialization, intracellular component | cellular component | GO:0099091 | 37 | 6 | 20747 | 1409 |
Abr,Psd,Srgn,Nr3c1,Lyn,Src |
| 3.696e-02 | -3.30 | regulation of polysaccharide biosynthetic process | biological process | GO:0032885 | 37 | 6 | 20694 | 1406 |
Irs2,Nfkb1,Pdgfb,Ptger4,Gfpt1,Dyrk2 |
| 3.696e-02 | -3.30 | response to fungus | biological process | GO:0009620 | 37 | 6 | 20694 | 1406 |
Myd88,Tlr2,Malt1,Syk,Pik3cd,Clec4n |
| 3.696e-02 | -3.30 | vasoconstriction | biological process | GO:0042310 | 37 | 6 | 20694 | 1406 |
Cav1,Edn1,Ednrb,Htr2b,Htr2a,Cd38 |
| 3.696e-02 | -3.30 | Regulation of KIT signaling | REACTOME pathways | R-MMU-1433559 | 15 | 4 | 8608 | 757 |
Socs1,Lyn,Src,Kitl |
| 3.699e-02 | -3.30 | GO_CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT | MSigDB lists | GO_CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT | 104 | 14 | 15632 | 1249 |
Rab21,Ap3b1,Rasgrp1,Hap1,Syne2,Ift57,Apba1,Kif5c,Uchl1,Hif1a,Kif3c,Wdr43,Ap3m2,Myo10 |
| 3.699e-02 | -3.30 | GO_VACUOLAR_LUMEN | MSigDB lists | GO_VACUOLAR_LUMEN | 104 | 14 | 15632 | 1249 |
Rnaset2a,Pdgfrb,Rab32,Agrn,Lnpep,Sdc2,Vcan,Cd74,Sdc1,Rnaset2b,Acp2,Jak2,Sdc4,Gpc1 |
| 3.699e-02 | -3.30 | MODULE_503 | MSigDB lists | MODULE_503 | 104 | 14 | 15632 | 1249 |
Lyn,Mppe1,Prdm1,Glrx,H3f3b,Lhx2,Plaur,Tnfrsf14,Bmp2,Cd14,Clic4,Slc25a37,Mecp2,Slc9a1 |
| 3.699e-02 | -3.30 | GO_EPIDERMAL_CELL_DIFFERENTIATION | MSigDB lists | GO_EPIDERMAL_CELL_DIFFERENTIATION | 104 | 14 | 15632 | 1249 |
Casp3,Flnb,Hdac1,Jag1,Slc4a7,Clic5,Ptch1,Map2k1,Sav1,Clic4,Notch1,Sec24b,Palld,Intu |
| 3.702e-02 | -3.30 | Folic Acid Network | WikiPathways | WP1273 | 23 | 6 | 4813 | 540 |
Gsr,Kmo,Selenow,Ptges,Txnrd1,Mthfr |
| 3.709e-02 | -3.29 | MZF1_01 | MSigDB lists | MZF1_01 | 215 | 25 | 15632 | 1249 |
Nr1h3,St3gal3,Lif,Gnb4,Pbx1,Hmga1,Flt1,Klf3,Cxcl14,Fut8,Tor1aip2,Rnf145,Kif3c,Itga5,H3f3b,Agpat4,Nlgn2,Zhx2,Cacna1d,Fam20c,Plekha4,Eif4g2,Brd2,Zeb1,Rtn2 |
| 3.711e-02 | -3.29 | GSE15330_LYMPHOID_MULTIPOTENT_VS_PRO_BCELL_UP | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_PRO_BCELL_UP | 184 | 22 | 15632 | 1249 |
Pim3,Tnfrsf14,Hvcn1,Plk3,Pttg1,Papss2,Bcl2a1d,Ankrd24,Dusp1,Src,Gypc,Bcl2a1b,Homer1,Serp1,Bcl2a1a,Clcf1,Ldlr,Hcar2,Nr4a3,Phlda1,Adora2a,Csrp1 |
| 3.711e-02 | -3.29 | GSE27786_NKTCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_NKTCELL_VS_ERYTHROBLAST_UP | 184 | 22 | 15632 | 1249 |
Ap3b1,Kdm5b,Cox17,Treml2,Aebp2,Ass1,Acpp,Bcl6,Zfp319,Egr1,Trim13,Trim14,Zc3h7a,Zfp36,Plscr1,Junb,Tor3a,Rgs1,Cldnd1,Zhx2,C3,Phf6 |
| 3.711e-02 | -3.29 | GSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_UP | 184 | 22 | 15632 | 1249 |
Parp11,Ell2,Nfil3,Hsd17b7,Rcl1,Pfkl,Gbp7,Ifit1bl2,Wars,Hivep3,St3gal5,Alas1,Ddit4,Spred3,Gbp3,Atp11a,Samhd1,Etv5,Sgcb,Cst7,Ifit1bl1,Slc44a1 |
| 3.711e-02 | -3.29 | GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP | MSigDB lists | GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP | 184 | 22 | 15632 | 1249 |
Rcl1,Ier3,Map3k8,Ifit3b,Socs1,Pim1,Fpr2,Dnaja2,Socs3,Tmod3,Hlx,Marcksl1,Stx11,Gsr,Gpr132,Ddit4,Klf2,Ifit3,Map4k4,Ccl12,Junb,Dusp1 |
| 3.711e-02 | -3.29 | GSE360_DC_VS_MAC_T_GONDII_DN | MSigDB lists | GSE360_DC_VS_MAC_T_GONDII_DN | 184 | 22 | 15632 | 1249 |
Bcl2a1a,Rnd3,Gpc1,Cd14,Fcgr1,Gbe1,Bnip3,Reps1,Akt3,Htra1,St3gal5,Vcan,Arhgap26,Cebpd,Kctd12,Bcl2a1d,S100a8,Eno2,Dusp6,Bcl2a1b,Fos,Gem |
| 3.711e-02 | -3.29 | GSE20715_WT_VS_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_LUNG_UP | 184 | 22 | 15632 | 1249 |
Dnaja2,Tmod3,Il2rg,Ifit3b,Cyth3,Ptgs2,Fpr2,Clic4,Rnd3,Angpt1,Lrrc8c,Myo10,Rcl1,Sqstm1,Cd302,Map2k1,Golga3,Samsn1,Lgals9,Ifit3,Parp12,Snx2 |
| 3.711e-02 | -3.29 | GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 184 | 22 | 15632 | 1249 |
Ell2,Ak4,Acsl1,Spata5l1,Mul1,Sema4a,Rbms1,Vcam1,Gca,Slc48a1,Gng12,Abcc4,Gadd45b,Lrp4,Ttc39c,Znfx1,Lcn2,Cep350,Gclm,Oaf,Slpi,Tmem26 |
| 3.716e-02 | -3.29 | GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 321 | 35 | 15632 | 1249 |
Rnf31,Casp8,Fzd5,Tnfsf14,Slc9a1,Rhou,Csf3,Zc3h12a,Tlr9,Tlr3,Il18,Il12b,Tlr2,Ptgs2,Hcls1,Bambi,Jak2,Il1b,Stard7,Lrp4,Bcl2l11,Ccl12,Tnf,Ezr,Il6,Micall2,Mdm2,Rbpms,Lif,Pml,Plk3,Sphk1,Cdk5r1,Ddx58,Plagl2 |
| 3.722e-02 | -3.29 | BIOCARTA_BIOPEPTIDES_PATHWAY | MSigDB lists | BIOCARTA_BIOPEPTIDES_PATHWAY | 40 | 7 | 15632 | 1249 |
Stat5a,Stat1,Stat2,Map2k1,Jak2,Stat3,Stat4 |
| 3.722e-02 | -3.29 | KRAS.50_UP.V1_UP | MSigDB lists | KRAS.50_UP.V1_UP | 40 | 7 | 15632 | 1249 |
Dhrs9,Kif5c,St3gal6,Dock4,Fabp3,Etv5,Glrx |
| 3.722e-02 | -3.29 | GO_IMMUNOGLOBULIN_PRODUCTION | MSigDB lists | GO_IMMUNOGLOBULIN_PRODUCTION | 40 | 7 | 15632 | 1249 |
Batf,Pou2f2,H2-Ab1,Fas,H2-Eb1,Traf3ip2,Swap70 |
| 3.722e-02 | -3.29 | GO_MORPHOGENESIS_OF_AN_EPITHELIAL_SHEET | MSigDB lists | GO_MORPHOGENESIS_OF_AN_EPITHELIAL_SHEET | 40 | 7 | 15632 | 1249 |
Flrt3,Itga5,Rhoc,Phactr4,Acvrl1,Notch1,Jag1 |
| 3.722e-02 | -3.29 | GALLUZZI_PERMEABILIZE_MITOCHONDRIA | MSigDB lists | GALLUZZI_PERMEABILIZE_MITOCHONDRIA | 40 | 7 | 15632 | 1249 |
Bnip3,Casp3,Clic4,Casp2,Nr4a1,Sod2,Bcl2l11 |
| 3.723e-02 | -3.29 | mitochondrion | cellular component | GO:0005739 | 1756 | 138 | 20747 | 1409 |
Cmpk2,Rab32,Aim2,Slc9a1,Mtcp1,Phyh,Sp140,Ciapin1,Higd1a,Txn1,Xaf1,Sod2,Rai14,Aldh1b1,Hap1,Slc25a22,Irgm2,Pgs1,Bcl2a1d,Bcl2l11,Nfkb1,Hspa1b,Fgr,Adhfe1,P2ry12,Cycs,Ociad1,Hk3,Gmppb,Kmo,Ak4,Gpd2,Lyn,Fam162a,Alas1,Ranbp2,Rmdn3,Bcl2a1a,Tomm70a,Prdx5,Hk2,Slc25a12,Jarid2,Tap1,Lipe,Pdk3,Tdrd7,Acsl5,Pcx,P4ha1,Slc25a25,Mx2,Rars,Nr3c1,Map2k1,Maff,Slc16a1,Mul1,Asah2,Acsl1,Ifit3b,Sco1,Cox17,P2ry2,Stard7,Hspa2,Cav1,Gk,Mtus1,1600014C10Rik,Prdx1,Mthfd1l,Rsad2,Slc44a1,Top3a,Plekhn1,Ppm1k,Casp4,Fam72a,Hk1,Prkce,Acod1,Stat3,Cox18,Txnrd1,Hspa1a,Me1,Mthfd2,Ikbke,Pdss1,Adap2,Hcls1,Agpat4,Trim14,AA467197,Mx1,Pmaip1,Ctu1,Prnp,Src,Gsr,Ifit3,Stap1,Ass1,Ripk3,Syne2,Arg2,Sirt1,Snn,Bnip3,Dnaja1,Vasn,Mtfr2,Stxbp1,Clic4,Glrx,Casp8,Mrpl52,Ldha,Nt5c3,Bcl2a1b,Slc25a37,Ppp1r15a,Idi1,Cnp,Mxd1,Ptges,Armcx6,Casp2,Parp9,Pnpt1,Tspo,Ddit4,Lap3,Coa5,Vrk2,Gja1,Sqstm1 |
| 3.725e-02 | -3.29 | MODULE_480 | MSigDB lists | MODULE_480 | 85 | 12 | 15632 | 1249 |
Pilrb2,Pilrb1,Ifi35,Rnf139,Frmd4a,Aldh1b1,Zeb1,Cish,Snx2,Crbn,Timp1,Hspa1a |
| 3.731e-02 | -3.29 | protein tetramerization | biological process | GO:0051262 | 180 | 19 | 20694 | 1406 |
Evl,Me1,Acpp,Pdss1,Agrn,Samhd1,Cd74,Txnrd1,Kcnj2,Homer1,Gfpt1,Cutc,Itpr1,Igf1r,Pfkl,Ccl5,Vasp,Lrp4,Sod2 |
| 3.740e-02 | -3.29 | MAPK targets/ Nuclear events mediated by MAP kinases | REACTOME pathways | R-MMU-450282 | 29 | 6 | 8608 | 757 |
Fos,Mapkapk2,Ppp2r1b,Jun,Dusp6,Dusp4 |
| 3.748e-02 | -3.28 | GPROTEING | prints domains | PR00321 | 12 | 3 | 5821 | 374 |
Gng11,Gng12,Gng4 |
| 3.755e-02 | -3.28 | male sex differentiation | biological process | GO:0046661 | 145 | 16 | 20694 | 1406 |
Ccnd1,Nupr1,Icam1,Inhba,Stat5a,Gja1,Kdr,Arid4a,Cited2,Fndc3a,Crkl,Hmga2,Bcl2l11,H3f3b,Arid5b,Insl6 |
| 3.757e-02 | -3.28 | GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_DN | 174 | 21 | 15632 | 1249 |
Rbl1,Rnf34,Traf5,Prdx1,Asf1a,Tmem123,Ccnd2,Mcm6,Ifih1,Pigv,Nck1,Crkl,Kif5c,Dck,Sirt1,Ift57,Fut8,Stxbp3,Pnp2,Higd1a,D16Ertd472e |
| 3.757e-02 | -3.28 | ZHANG_TLX_TARGETS_36HR_DN | MSigDB lists | ZHANG_TLX_TARGETS_36HR_DN | 174 | 21 | 15632 | 1249 |
Rbl1,Dek,Pnpt1,Phip,Fam111a,Sass6,Pdzd11,Tpx2,Kpna3,Mcm10,Egln3,Hat1,Zc3h7a,Trip13,Timeless,Tgs1,Rbbp8,Ifit2,Atm,Cenpe,Psip1 |
| 3.757e-02 | -3.28 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | 174 | 21 | 15632 | 1249 |
Slc39a14,Fut8,Casp3,Vps54,Birc2,Lap3,Tmem184b,Cd14,Inpp1,Sec24a,Gfpt1,Isg15,Sema4a,Tapbpl,Rcn1,Trib1,Fndc3a,Ifi35,Prdm1,Etnk1,Rars |
| 3.759e-02 | -3.28 | carboxylic acid binding | molecular function | GO:0031406 | 212 | 22 | 20217 | 1400 |
Rars,Nos2,Fabp3,Gfpt1,P4ha2,Pcx,Gclc,Fabp7,Plod2,Egln3,P4ha1,Phyh,Sele,Sesn3,Ass1,Vcan,Hdc,S100a8,Plod3,Siglece,Stard5,Layn |
| 3.761e-02 | -3.28 | CYCLINS | prosite domains | PS00292 | 10 | 3 | 13278 | 1037 |
Ccnd1,Ccnd2,Ccne1 |
| 3.767e-02 | -3.28 | protein-containing complex | cellular component | GO:0032991 | 5290 | 388 | 20747 | 1409 |
Ankib1,Traf5,Nr4a3,Mdm2,Riox2,Mcm10,Kif3c,Il2rg,Ppp2r2a,Eif4g2,Ranbp2,Arid4a,Ppp2r1b,Il12b,Lrrc8c,Olr1,Fscn1,Rel,Cacna1d,Rnf139,Tlr2,Golga3,Rac3,Icosl,Hivep2,Itga9,Nupr1,Nfkb1,Polr2g,Nfkb2,Malt1,Psmd10,Sec24a,Dach1,Slc9a1,Ptgs2,Notch2,Dcun1d3,Hp,Usp25,Gclm,Dnajb2,Rffl,Max,Cd34,Aebp2,Mcm6,Birc3,Pf4,Calcrl,Clic5,Tmem67,Parp9,Ahr,Zfp36,Tcea1,Pdlim7,H2-Q7,Vrk2,Sqstm1,Ell2,Pik3r6,Notch1,Tlr6,Stxbp1,Cpeb4,Carhsp1,Tap2,H2-Q6,Trim21,Hspa1a,Palld,Cenpe,Gpr84,Pdss1,Hcls1,Med13,Cdkn2d,Cd69,Hif1a,Pigv,Tnfaip2,Rictor,Psma6,Ppp1r15b,Pik3cd,Ep400,Relb,Ccnd2,Col4a2,Armc8,Ascc3,Acvr1,Ccnd1,Jarid2,Zc3h12a,Lmo4,P4ha1,Axl,Casp1,Myo10,Rnf19b,Cdkn1a,Aff1,Socs7,Apaf1,Nlrc4,Gna15,Pik3r5,Atf3,Gfi1,Pdgfrb,Cd40,Etv3,Hhex,Mcm9,Pcgf5,Psmb8,Ifitm1,Psmb10,Traf1,Irf4,Il6,Snx2,Cish,Ccng2,Ebi3,Scn1b,Hspa1b,Ube2e1,Aim2,Acvrl1,Atp6v1d,Cited2,Met,Fas,Tra2a,Ddx4,Gsdmd,Larp1,Cop1,Rnf31,Yju2,Magohb,Rbl1,Fos,Resf1,Stx11,Lox,Pfkl,Kdm5b,Bcor,Wdr59,Ldlr,Noc4l,P4ha2,Dync1i2,Tmod3,Jun,Zeb1,Psmb9,Kdm6b,Kctd12,Nox1,Snapc1,Rbms1,Nr4a1,Ikzf1,AA467197,Fcho2,Ctu1,H2-Ab1,Stip1,Igf1r,Rrs1,Hspa2,Hsph1,Irs2,Gch1,Casp4,Rnf19a,Eno2,Trim12c,Nxf1,Dtx3l,Sap30,H2-Eb1,Znfx1,Tap1,Cd80,Rbpms,Tdrd7,Gclc,Adrb2,Tent4a,Lrp8,Tpm4,Prpf38a,Uaca,Sipa1l1,Tank,Spen,Rars,Pla2g7,Flt1,Inhba,Ripk2,Syk,Clcf1,Prkx,Mier3,Sesn3,Cnot4,Nek6,Med21,Itga4,Lyn,Sec24b,Gpd2,Cyfip1,Stx6,Stat1,Tomm70a,Timeless,Adar,Ap3b1,Rapgef2,Apba1,Kdr,Plekha2,Dbnl,Carmil1,Bcl2l11,Naa25,Smc5,Vcam1,Hat1,Cacybp,Il4ra,Birc2,Csf1,Kcnj2,Tapbp,Socs1,Sdc1,Col18a1,Ap3m2,Psme1,Kdm4a,Sinhcaf,Cd74,Pbx1,Ccne1,Socs3,H2-Q4,H3f3b,Pnpt1,Pou3f1,Itga5,Gja1,Cflar,H2-Aa,Tlr1,Bcl9,Ksr1,Casp8,Mrpl52,Actb,Nck1,Mcmbp,Itgal,Rbms2,Ezr,Lcp2,Eif2ak2,Vezt,Hmga1,Acvr1b,Ago3,Rbbp8,Cav1,Kat2b,Nod2,Nfkbia,Col11a2,Ppp2r3a,Hk1,Stat3,Msr1,Ccnj,Stau1,Gnb4,Crbn,Prpf4,Phf6,Ift22,Itgav,Smg7,Marco,Nfkbiz,Nr3c1,Aftph,Gpsm2,Pde3b,Il13ra1,Ppp2r5a,Traf2,C3,Ric1,Hdac1,Kif5c,Nr1h3,Col27a1,Ppp4r2,Mecp2,Ift57,Crkl,Il12rb1,Itgb8,Hk3,Ube2l6,Sgcb,Cacnb3,Myc,Il18rap,Rnf14,Higd1a,Csf3r,Myd88,Taf4b,Thbs1,Eef1e1,Bmp2,Itpr1,Zswim4,Arid5a,Tnks1bp1,Mov10,Cdk5r1,Ppp1r15a,Chmp4b,Mpp7,Tle3,Dmxl2,Dcp2,Saa3,Gng11,Wars,Kif9,Casp3,Dr1,Mocs1,Syne2,Sirt1,Nlrp3,Junb,Klhl25,Kcna3,Psmb6,Clic4,Jmjd6,Dyrk2,Dync1h1,Tcf4,Parp11,Prkar2b,Gng12,Cd14,Myo1b,Dcp1a,Pde4b,Mmp9,Xrn1,Keap1,Src,G3bp2,Noct,Stap1,Eno1,Atm,Atp2b4,Vps54,Fbxo4,Gng4,Mefv,Asf1a,Spsb1,Ikbkg |
| 3.771e-02 | -3.28 | Myc (myelocytomatosis oncogene) | protein interactions | 17869 | 63 | 11 | 7778 | 753 |
Cdkn1a,Ccnd2,Hspa1b,H3f3b,Cav1,Odc1,Max,Pdgfrb,Ldha,Thbs1,Ccnd1 |
| 3.772e-02 | -3.28 | ATF6_01 | MSigDB lists | ATF6_01 | 114 | 15 | 15632 | 1249 |
Slc39a13,Gng4,Egr1,Egr3,Dnajb2,Tle3,Arf4,Lmo4,Brd2,Nr4a1,Etv6,Leng9,Dusp4,Egr2,Stat3 |
| 3.786e-02 | -3.27 | alpha-amino acid biosynthetic process | biological process | GO:1901607 | 57 | 8 | 20694 | 1406 |
Psat1,Tha1,Mthfr,Asns,Plod3,Ass1,Phgdh,Plod2 |
| 3.786e-02 | -3.27 | regulation of focal adhesion assembly | biological process | GO:0051893 | 57 | 8 | 20694 | 1406 |
Kdr,Acvrl1,Src,Map4k4,Ptprj,Sdc4,Ptk2,Mmp14 |
| 3.786e-02 | -3.27 | positive regulation of organ growth | biological process | GO:0046622 | 57 | 8 | 20694 | 1406 |
Trip10,Hlx,Notch1,Pim1,Nr3c1,Serp1,Sirt1,Edn1 |
| 3.786e-02 | -3.27 | regulation of cell-substrate junction assembly | biological process | GO:0090109 | 57 | 8 | 20694 | 1406 |
Ptk2,Mmp14,Map4k4,Sdc4,Src,Ptprj,Kdr,Acvrl1 |
| 3.786e-02 | -3.27 | amine metabolic process | biological process | GO:0009308 | 57 | 8 | 20694 | 1406 |
Vcam1,Mecp2,Sat1,Smox,Hdc,Kmo,Odc1,Srm |
| 3.786e-02 | -3.27 | heart valve development | biological process | GO:0003170 | 57 | 8 | 20694 | 1406 |
Notch1,Jag1,Bmp2,Acvr1,Notch2,Tnfrsf1b,Prdm1,Mdm2 |
| 3.795e-02 | -3.27 | synapse assembly | biological process | GO:0007416 | 78 | 10 | 20694 | 1406 |
Agrn,Lrp4,Ntng2,Flrt3,Fzd5,Crkl,Pdgfb,Dbnl,Mecp2,Nlgn2 |
| 3.795e-02 | -3.27 | nucleoside diphosphate metabolic process | biological process | GO:0009132 | 78 | 10 | 20694 | 1406 |
Cmpk2,Tpi1,Eno2,Pgk1,Ampd3,Hk1,Ak4,Pfkl,Hk2,Hk3 |
| 3.795e-02 | -3.27 | GSE3982_MAC_VS_BCELL_DN | MSigDB lists | GSE3982_MAC_VS_BCELL_DN | 164 | 20 | 15632 | 1249 |
Bcor,Ppa1,Col18a1,Psme1,Egr3,Hhex,Il15ra,Zbp1,Herc3,Osbpl3,Casp4,Ubr4,Psd4,4930523C07Rik,Birc3,Ezr,Oas2,Uba7,Stoml1,Cnot4 |
| 3.795e-02 | -3.27 | GSE6259_DEC205_POS_DC_VS_CD8_TCELL_UP | MSigDB lists | GSE6259_DEC205_POS_DC_VS_CD8_TCELL_UP | 164 | 20 | 15632 | 1249 |
Slc28a2,Glrx,Ripk3,Epsti1,Pde3b,Tspo,Gtpbp2,Traf1,Rhoh,Rnf19b,Ogfrl1,Peli1,Pnp2,Nmi,Serp1,Gpsm2,Gna15,Psmb9,Plekhf2,Psmb8 |
| 3.795e-02 | -3.27 | GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_UP | 164 | 20 | 15632 | 1249 |
Fos,Ccr1,Slc31a2,Ezr,Ccng2,Il12rb1,Zfp36,Dbnl,Ccr3,Rab20,Mmp25,Tmtc2,Tmod3,Col18a1,Lrp8,Hmgcs1,Ier2,Ifi35,Ripk3,Tnfrsf8 |
| 3.795e-02 | -3.27 | GSE15659_NAIVE_CD4_TCELL_VS_ACTIVATED_TREG_DN | MSigDB lists | GSE15659_NAIVE_CD4_TCELL_VS_ACTIVATED_TREG_DN | 164 | 20 | 15632 | 1249 |
Ppm1k,Tor1aip1,Tnf,Wars,S1pr2,Rnf19a,Rbpms,Zscan29,Psma6,Tdrd7,Ppp2r5a,Top3a,Ppp4r2,Slc43a3,Spata5l1,Sema4a,Prdm1,Tpi1,Rhoh,Rhoc |
| 3.805e-02 | -3.27 | MAPK3 (ERK1) activation | REACTOME pathways | R-MMU-110056 | 9 | 3 | 8608 | 757 |
Jak2,Il6,Map2k1 |
| 3.805e-02 | -3.27 | Glutathione synthesis and recycling | REACTOME pathways | R-MMU-174403 | 9 | 3 | 8608 | 757 |
Gclm,Ggct,Gclc |
| 3.807e-02 | -3.27 | Dok1 (docking protein 1) | protein interactions | 13448 | 20 | 5 | 7778 | 753 |
Lyn,Syk,Fcgr2b,Nck1,Phgdh |
| 3.812e-02 | -3.27 | GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 519 | 53 | 15632 | 1249 |
Mgat1,Serp1,Dse,Abcc5,Dpy19l1,B3gnt5,Fut8,Pigv,St3gal6,Calcrl,Upp1,Parp10,Pdgfrb,Oas2,Adora2a,Phlda1,Gbgt1,Ext1,Ak4,Parp3,St3gal1,Cmpk2,Htr2b,Il1b,Plaur,Gcnt2,Thbs1,Tiparp,B4galt4,Tet2,Agrn,Sdc2,Chst11,Vcan,Gmppb,Papss2,Sdc1,Tpi1,St3gal3,Angpt1,Gpc1,Extl2,Sdc4,Sirt1,St3gal5,Ampd3,Plscr1,Mppe1,Dck,Tnip1,Ust,Arf4,Gfpt1 |
| 3.815e-02 | -3.27 | lamellipodium organization | biological process | GO:0097581 | 47 | 7 | 20694 | 1406 |
Whamm,Cyfip1,Nck1,Snx2,Spata13,P2ry12,Carmil1 |
| 3.815e-02 | -3.27 | cellular amine metabolic process | biological process | GO:0044106 | 47 | 7 | 20694 | 1406 |
Mecp2,Sat1,Hdc,Smox,Kmo,Srm,Odc1 |
| 3.815e-02 | -3.27 | osteoclast differentiation | biological process | GO:0030316 | 47 | 7 | 20694 | 1406 |
Tnf,Csf1,Snx10,Src,Junb,Fam20c,Cd300lf |
| 3.815e-02 | -3.27 | positive regulation of calcium-mediated signaling | biological process | GO:0050850 | 47 | 7 | 20694 | 1406 |
Hap1,Tnf,Syk,Slc9a1,Itgal,Ccl4,Kdr |
| 3.815e-02 | -3.27 | bone mineralization | biological process | GO:0030282 | 47 | 7 | 20694 | 1406 |
Fgr,Mmp13,Sbds,Snx10,Bmp2,Ptgs2,Lox |
| 3.815e-02 | -3.27 | L-alpha-amino acid transmembrane transport | biological process | GO:1902475 | 47 | 7 | 20694 | 1406 |
Slc7a11,Slc7a5,Slc25a22,Slc7a8,Slc7a2,Slc25a12,Slc13a3 |
| 3.816e-02 | -3.27 | GO_LEADING_EDGE_MEMBRANE | MSigDB lists | GO_LEADING_EDGE_MEMBRANE | 124 | 16 | 15632 | 1249 |
Ddx58,Spata13,Fgr,Ptprj,Itga5,Arf4,Src,Ezr,Plek,Itgav,Syne2,Vasp,Spry2,Pdpn,Piezo1,Antxr1 |
| 3.820e-02 | -3.27 | signal transduction involved in DNA integrity checkpoint | biological process | GO:0072401 | 28 | 5 | 20694 | 1406 |
Pml,Casp2,Atm,Mdm2,Cdkn1a |
| 3.820e-02 | -3.27 | signal transduction involved in cell cycle checkpoint | biological process | GO:0072395 | 28 | 5 | 20694 | 1406 |
Pml,Casp2,Atm,Mdm2,Cdkn1a |
| 3.820e-02 | -3.27 | regulation of cell growth involved in cardiac muscle cell development | biological process | GO:0061050 | 28 | 5 | 20694 | 1406 |
Sirt1,Edn1,Nr3c1,Tomm70a,Trip10 |
| 3.820e-02 | -3.27 | positive regulation of protein deacetylation | biological process | GO:0090312 | 28 | 5 | 20694 | 1406 |
Bcl6,Pml,Jdp2,Sirt1,Ripk3 |
| 3.820e-02 | -3.27 | signal transduction involved in DNA damage checkpoint | biological process | GO:0072422 | 28 | 5 | 20694 | 1406 |
Casp2,Pml,Cdkn1a,Mdm2,Atm |
| 3.820e-02 | -3.27 | negative regulation of osteoclast differentiation | biological process | GO:0045671 | 28 | 5 | 20694 | 1406 |
Clec2d,Ifnb1,Pilrb1,Ubash3b,Tmem178 |
| 3.820e-02 | -3.27 | neurotrophin signaling pathway | biological process | GO:0038179 | 28 | 5 | 20694 | 1406 |
Casp3,Ddit4,Src,Hap1,Rapgef2 |
| 3.820e-02 | -3.27 | apoptotic process involved in development | biological process | GO:1902742 | 28 | 5 | 20694 | 1406 |
Ppp2r1b,Fzd5,Bcl2l11,Xkr8,Notch1 |
| 3.820e-02 | -3.27 | regulation of spindle assembly | biological process | GO:0090169 | 28 | 5 | 20694 | 1406 |
Hspa1b,Dync1h1,Chmp4b,Hspa1a,Gpsm2 |
| 3.820e-02 | -3.27 | negative regulation of organic acid transport | biological process | GO:0032891 | 28 | 5 | 20694 | 1406 |
Il1b,Tnf,Il1rn,Irs2,Thbs1 |
| 3.827e-02 | -3.26 | SHI_SPARC_TARGETS_UP | MSigDB lists | SHI_SPARC_TARGETS_UP | 24 | 5 | 15632 | 1249 |
Ppp1r15a,Mdm2,Sema3c,Ahrr,Gadd45b |
| 3.827e-02 | -3.26 | STEGER_ADIPOGENESIS_DN | MSigDB lists | STEGER_ADIPOGENESIS_DN | 24 | 5 | 15632 | 1249 |
Plat,Pdpn,Pla2g7,Lox,Olfml3 |
| 3.827e-02 | -3.26 | HORTON_SREBF_TARGETS | MSigDB lists | HORTON_SREBF_TARGETS | 24 | 5 | 15632 | 1249 |
Me1,Hsd17b7,Ldlr,Idi1,Hmgcs1 |
| 3.827e-02 | -3.26 | GO_PROTEIN_DEALKYLATION | MSigDB lists | GO_PROTEIN_DEALKYLATION | 24 | 5 | 15632 | 1249 |
Kdm6b,Jmjd6,Arid5b,Kdm5b,Kdm4a |
| 3.827e-02 | -3.26 | GO_MITOGEN_ACTIVATED_PROTEIN_KINASE_BINDING | MSigDB lists | GO_MITOGEN_ACTIVATED_PROTEIN_KINASE_BINDING | 24 | 5 | 15632 | 1249 |
Sirt1,Ptafr,Ptprj,Tnip1,Dusp2 |
| 3.827e-02 | -3.26 | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_UP | 24 | 5 | 15632 | 1249 |
Casp3,Sat1,Trim21,Irf1,Aldh1b1 |
| 3.827e-02 | -3.26 | YE_METASTATIC_LIVER_CANCER | MSigDB lists | YE_METASTATIC_LIVER_CANCER | 24 | 5 | 15632 | 1249 |
Itga9,Cenpe,Inpp5b,Irf2,Mmp9 |
| 3.827e-02 | -3.26 | GO_NEGATIVE_REGULATION_OF_LIPID_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LIPID_TRANSPORT | 24 | 5 | 15632 | 1249 |
Itgav,Nfkb1,Thbs1,Nr1h3,Irs2 |
| 3.827e-02 | -3.26 | MARCINIAK_ER_STRESS_RESPONSE_VIA_CHOP | MSigDB lists | MARCINIAK_ER_STRESS_RESPONSE_VIA_CHOP | 24 | 5 | 15632 | 1249 |
Kitl,Ampd3,Ppp1r15a,Tcea1,Ets2 |
| 3.827e-02 | -3.26 | GO_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 24 | 5 | 15632 | 1249 |
Gpc1,Thbs1,Fam20c,Dusp6,Spry2 |
| 3.827e-02 | -3.26 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | MSigDB lists | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | 24 | 5 | 15632 | 1249 |
Hdac1,Rbl1,Serpine1,Junb,Myc |
| 3.827e-02 | -3.26 | SA_B_CELL_RECEPTOR_COMPLEXES | MSigDB lists | SA_B_CELL_RECEPTOR_COMPLEXES | 24 | 5 | 15632 | 1249 |
Syk,Map2k1,Jun,Lyn,Fos |
| 3.827e-02 | -3.26 | GO_PROTEIN_LOCALIZATION_TO_CILIUM | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_CILIUM | 24 | 5 | 15632 | 1249 |
Arf4,Ehd1,Snx10,Atp6v1d,Tulp3 |
| 3.827e-02 | -3.26 | GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_4 | MSigDB lists | GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_4 | 24 | 5 | 15632 | 1249 |
Il2rg,Nfil3,Il4ra,Keap1,Pml |
| 3.827e-02 | -3.26 | JI_METASTASIS_REPRESSED_BY_STK11 | MSigDB lists | JI_METASTASIS_REPRESSED_BY_STK11 | 24 | 5 | 15632 | 1249 |
Gdf15,Pbx1,Mtus1,Glrx,Dusp4 |
| 3.836e-02 | -3.26 | WEI_MIR34A_TARGETS | MSigDB lists | WEI_MIR34A_TARGETS | 134 | 17 | 15632 | 1249 |
Palld,Hmgcs1,Plagl1,Rcan1,Col4a2,Pkp4,Tmem184b,Map2k1,Pdgfrb,Slc7a2,Swap70,Ppp4r2,Slc44a1,Rhoq,Fut8,Mid1,Casp2 |
| 3.836e-02 | -3.26 | GSE4984_UNTREATED_VS_VEHICLE_CTRL_TREATED_DC_UP | MSigDB lists | GSE4984_UNTREATED_VS_VEHICLE_CTRL_TREATED_DC_UP | 134 | 17 | 15632 | 1249 |
Orai2,Rnf34,Ccdc88b,Calcrl,Tlr9,St3gal1,Itga5,Tlr6,Itpkc,Acvrl1,Cers6,Nr3c1,Nat2,Rab11fip1,Dse,Oas3,Ccl12 |
| 3.839e-02 | -3.26 | FRASOR_RESPONSE_TO_ESTRADIOL_DN | MSigDB lists | FRASOR_RESPONSE_TO_ESTRADIOL_DN | 76 | 11 | 15632 | 1249 |
Rnd3,Ddit4,Dusp4,Mmd,Stxbp1,Abcc5,Klf6,Dusp1,Ier3,Plk2,Myo1b |
| 3.839e-02 | -3.26 | LRR_6 | pfam domains | PF13516 | 54 | 8 | 18711 | 1348 |
Tlr2,Carmil1,Nod2,Nod1,Ciita,Nlrp3,Nlrc5,Phlpp1 |
| 3.844e-02 | -3.26 | cellular response to topologically incorrect protein | biological process | GO:0035967 | 89 | 11 | 20694 | 1406 |
Hspa1a,Ppp1r15a,Serp1,Hspa1b,Hspa2,Optn,Ero1l,Ccnd1,Daxx,Eif2ak2,Atf3 |
| 3.844e-02 | -3.26 | negative regulation of cation transmembrane transport | biological process | GO:1904063 | 89 | 11 | 20694 | 1406 |
Prkce,Ahr,Cav1,Mmp9,Gpr35,Slc30a1,Tlr9,Cacnb3,Gem,Agrn,Stoml1 |
| 3.860e-02 | -3.25 | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | 398 | 42 | 15632 | 1249 |
Rnd3,Cd83,Klf7,Ahr,Itga4,Palld,Bcor,Hif1a,Ubash3b,Socs1,Dusp2,Pde1b,Sdc2,Dusp4,P4ha2,Armcx6,Hivep2,Cenpe,Gypc,Slc16a3,Dock4,Tcf4,Thbs1,Ralgds,Pkp4,Pmepa1,Kdm6b,Larp1,Cd55,Filip1l,Dennd2a,Tgfbi,Irf1,Arid5b,Nrp2,Pdlim7,Antxr1,Inhba,Egln3,Ahrr,Asns,Pdgfrb |
| 3.866e-02 | -3.25 | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | 32 | 6 | 15632 | 1249 |
Rabgef1,Abr,Ptger4,Ccl12,Hmox1,Stap1 |
| 3.866e-02 | -3.25 | GO_CELLULAR_RESPONSE_TO_ALKALOID | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ALKALOID | 32 | 6 | 15632 | 1249 |
Icam1,Nfkb1,Ccl5,Tnf,Mdm2,Plau |
| 3.866e-02 | -3.25 | GO_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | 32 | 6 | 15632 | 1249 |
Ifnb1,Il4ra,Bcl6,Samsn1,Tnfsf4,Spn |
| 3.866e-02 | -3.25 | GO_ACTIVATION_OF_JUN_KINASE_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_JUN_KINASE_ACTIVITY | 32 | 6 | 15632 | 1249 |
Mul1,Map3k6,Syk,Daxx,Mdfic,Dbnl |
| 3.866e-02 | -3.25 | AR_02 | MSigDB lists | AR_02 | 32 | 6 | 15632 | 1249 |
Dnajb4,Lox,Bcl6,Il27,Smox,Slc7a8 |
| 3.866e-02 | -3.25 | GO_NEGATIVE_REGULATION_OF_BLOOD_CIRCULATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_BLOOD_CIRCULATION | 32 | 6 | 15632 | 1249 |
Dock4,Cx3cl1,Pde5a,Hif1a,Zc3h12a,Jak2 |
| 3.866e-02 | -3.25 | ST_ERK1_ERK2_MAPK_PATHWAY | MSigDB lists | ST_ERK1_ERK2_MAPK_PATHWAY | 32 | 6 | 15632 | 1249 |
Klf6,Nfkb1,Dusp6,Map3k8,Map2k1,Dusp4 |
| 3.866e-02 | -3.25 | GO_UBIQUITIN_LIKE_PROTEIN_CONJUGATING_ENZYME_BINDING | MSigDB lists | GO_UBIQUITIN_LIKE_PROTEIN_CONJUGATING_ENZYME_BINDING | 32 | 6 | 15632 | 1249 |
Rnf19b,Ankib1,Rnf114,Dcun1d3,Rnf14,Rnf19a |
| 3.866e-02 | -3.25 | GO_BLOOD_VESSEL_REMODELING | MSigDB lists | GO_BLOOD_VESSEL_REMODELING | 32 | 6 | 15632 | 1249 |
Lif,Axl,Acvrl1,Sema3c,Mdm2,Jag1 |
| 3.866e-02 | -3.25 | REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS | MSigDB lists | REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS | 32 | 6 | 15632 | 1249 |
Gna15,Src,Gng4,Gng12,Gnb4,Gng11 |
| 3.866e-02 | -3.25 | ZHAN_LATE_DIFFERENTIATION_GENES_UP | MSigDB lists | ZHAN_LATE_DIFFERENTIATION_GENES_UP | 32 | 6 | 15632 | 1249 |
Cav1,Tspan3,Itga4,P4ha1,Dusp5,Jag1 |
| 3.866e-02 | -3.25 | PID_ALPHA_SYNUCLEIN_PATHWAY | MSigDB lists | PID_ALPHA_SYNUCLEIN_PATHWAY | 32 | 6 | 15632 | 1249 |
Hck,Fgr,Lyn,Src,Uchl1,Syk |
| 3.866e-02 | -3.25 | FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_UP | MSigDB lists | FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_UP | 32 | 6 | 15632 | 1249 |
Psat1,Flt1,Ptk2,Bcl2l11,Igf2bp2,Vegfc |
| 3.867e-02 | -3.25 | circadian rhythm | biological process | GO:0007623 | 134 | 15 | 20694 | 1406 |
Relb,Nos2,Egr1,Ahr,Fas,Nfil3,Gfpt1,Prokr1,Pml,Nampt,Ass1,Timeless,Hdac1,Noct,Sirt1 |
| 3.868e-02 | -3.25 | GO_ESTABLISHMENT_OF_CELL_POLARITY | MSigDB lists | GO_ESTABLISHMENT_OF_CELL_POLARITY | 95 | 13 | 15632 | 1249 |
Cyth3,Mpp7,Frmd4a,Ptk2,Mark2,Wdr43,Fscn1,Ust,Gpsm2,Ezr,Rictor,Rab10,Spry2 |
| 3.868e-02 | -3.25 | GO_GLAND_MORPHOGENESIS | MSigDB lists | GO_GLAND_MORPHOGENESIS | 95 | 13 | 15632 | 1249 |
Pml,Notch1,Cav1,Sema3c,Tet2,Ptch1,Ezr,Src,Tnf,Kdm5b,Tnc,Csf1,Il6 |
| 3.869e-02 | -3.25 | EGFR1 Signaling Pathway | WikiPathways | WP572 | 178 | 28 | 4813 | 540 |
Plscr1,Fos,Nck1,Jak2,Socs1,Ralgds,Arf4,Myc,Stxbp1,Stat1,Map2k1,Spry2,Src,Crkl,Stat3,Gja1,Hdac1,Socs3,Errfi1,Hat1,Reps1,Stat5a,Stat2,Jun,Pik3cd,Cav1,Dusp1,Tnip1 |
| 3.879e-02 | -3.25 | GO_ENDOPLASMIC_RETICULUM_PART | MSigDB lists | GO_ENDOPLASMIC_RETICULUM_PART | 1066 | 101 | 15632 | 1249 |
Notch1,Bfar,Agtrap,H2-Q7,Pml,Atp13a1,Tapbp,Minpp1,Rab9,Itpr1,Il15ra,Plaur,Slc37a3,Sec24b,Acsl5,Osbpl3,Thbs1,Ptgs2,Tapbpl,Shisa3,H2-Ab1,Zc3h12a,Uchl1,Pdgfb,Rnaset2a,Tap1,Tmtc2,Trim13,Ppm1l,Edn1,H2-Q4,Flrt3,Agpat4,Rnaset2b,Esd,Tmem67,Rcn1,Acsl1,Rasgrp1,Ksr1,Casp4,P4ha1,Pdgfc,1600014C10Rik,Cd74,Pigv,Ch25h,Rnf139,Cers6,Rsad2,Rab21,H2-Q6,Traf2,Rhbdf2,Serp1,P4ha2,Plod3,Ptges,Sec24a,Atp10a,Tlr3,Rtn1,Hmox1,Degs2,Ext1,Rab10,Piezo1,H2-Aa,Flrt2,Ppp1r15a,Tap2,Col11a2,Hsd17b12,Ttc9c,H2-Eb1,Gja1,F10,Extl2,Col4a2,Lpcat2,Col18a1,Cept1,Pla2g4a,Ctsc,Tor1aip2,Dnaja1,Dhrs9,Hsd17b7,Vrk2,Lrrc8c,Notch2,Col27a1,Mppe1,Mtdh,Tlr9,Syne2,Slc9a1,Rtn2,Cav1,Plod2,Tor3a |
| 3.889e-02 | -3.25 | PITX2_Q2 | MSigDB lists | PITX2_Q2 | 216 | 25 | 15632 | 1249 |
Trib1,Slc43a3,Cpeb4,Slc29a3,Bambi,Kitl,Lmo4,Ttc9c,Pde4b,Sesn3,Pdlim7,Med13,Ppm1l,Prdm1,Tnks1bp1,Rbms2,Pbx1,Hivep2,Pik3r5,Rbpms,Acvr1,Rin2,Tapbp,Gadd45g,Prkce |
| 3.895e-02 | -3.25 | LEE_LIVER_CANCER_MYC_UP | MSigDB lists | LEE_LIVER_CANCER_MYC_UP | 49 | 8 | 15632 | 1249 |
Mcm6,Lcn2,Tmem176b,Slc13a3,Hmgcs1,Pdgfc,Plat,Cish |
| 3.895e-02 | -3.25 | GO_REGULATION_OF_LIPID_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_LIPID_CATABOLIC_PROCESS | 49 | 8 | 15632 | 1249 |
Ldlr,Prkce,Pde3b,Hcar2,Il1b,Tnf,Irs2,Adrb2 |
| 3.895e-02 | -3.25 | GO_LYMPHOCYTE_HOMEOSTASIS | MSigDB lists | GO_LYMPHOCYTE_HOMEOSTASIS | 49 | 8 | 15632 | 1249 |
Lyn,Tnfaip3,Tnfsf14,Ripk3,Hif1a,Bcl2l11,Fas,Casp3 |
| 3.895e-02 | -3.25 | KEGG_GLUTATHIONE_METABOLISM | MSigDB lists | KEGG_GLUTATHIONE_METABOLISM | 49 | 8 | 15632 | 1249 |
Gsta3,Gsr,Ggct,Gclm,Gclc,Odc1,Lap3,Srm |
| 3.895e-02 | -3.25 | WONG_PROTEASOME_GENE_MODULE | MSigDB lists | WONG_PROTEASOME_GENE_MODULE | 49 | 8 | 15632 | 1249 |
Psmd10,Usp18,Psmb10,Psme1,Psmb8,Sqstm1,Psmb6,Usp25 |
| 3.895e-02 | -3.25 | GO_MONOSACCHARIDE_TRANSPORT | MSigDB lists | GO_MONOSACCHARIDE_TRANSPORT | 49 | 8 | 15632 | 1249 |
Hk1,Ezr,Slc2a1,Slc2a6,Stxbp3,Edn1,Hk2,Hk3 |
| 3.895e-02 | -3.25 | PID_TAP63_PATHWAY | MSigDB lists | PID_TAP63_PATHWAY | 49 | 8 | 15632 | 1249 |
Egr2,Nqo1,Cdkn1a,Mdm2,Jag1,Gdf15,Pml,Fas |
| 3.898e-02 | -3.24 | STAT_Q6 | MSigDB lists | STAT_Q6 | 237 | 27 | 15632 | 1249 |
Ppp2r3a,Lmo4,Fosb,Armc8,Dgkh,Rtn1,Dnaja2,Cacnb3,Tnip3,Nr4a3,Irf4,Cish,Mmp14,Rffl,Il18bp,Flrt3,Abcc5,Tet2,Arhgef3,Bcl6,Etv5,Irf2,Prdm1,Nek6,Apba1,Sertad3,Ifih1 |
| 3.907e-02 | -3.24 | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_DN | MSigDB lists | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_DN | 185 | 22 | 15632 | 1249 |
Pcx,Gbp9,Pde1b,Gbp4,Tor1aip2,Ctsc,Nr4a1,Slc30a1,Rictor,Mmp13,Il12rb1,Jag1,Serpine1,Hsd17b7,Lrrc8c,Snn,Ap3m2,Plat,Dr1,Slc25a22,Denr,Rnf19b |
| 3.907e-02 | -3.24 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | MSigDB lists | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | 185 | 22 | 15632 | 1249 |
Lpar1,Fpr2,Fpr1,P2ry14,Cxcl10,Gng4,C3,Gng12,Pf4,Hcar2,Gnb4,Cxcl1,Gng11,Rgs1,Gpr18,P2ry12,P2ry13,Ccr1,Ccl5,S1pr2,Cxcl2,Ccr3 |
| 3.907e-02 | -3.24 | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | 185 | 22 | 15632 | 1249 |
Rgl1,Ptch1,Nrp2,Sap30,Flnb,Nfkbid,Fzd1,Cd69,Irf1,Il12b,Snapc1,Esd,Plekhn1,Spsb1,Gclm,Lrch1,Il4i1,Batf2,Cept1,Kremen1,Irs2,Znrf3 |
| 3.907e-02 | -3.24 | GSE10240_CTRL_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_CTRL_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 185 | 22 | 15632 | 1249 |
Gramd1a,Ezr,Lgals9,Phlda1,Rab11fip1,Ikzf1,Micall2,Triobp,Casp2,Mafk,Itga4,Irf2,Il4ra,Serpinb9,Pim1,Ccl4,Hcls1,Lpcat2,Atp11b,Dusp28,Tnfaip3,Nlgn2 |
| 3.907e-02 | -3.24 | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_UP | MSigDB lists | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_UP | 185 | 22 | 15632 | 1249 |
Uchl1,Ier2,Ptk2,Endod1,Tmem176b,Pgs1,Il4ra,Prnp,Mob3b,Pik3r5,Zswim4,Ahrr,Myadm,Mier3,Tcf4,Lmo4,Gpsm2,Trip10,Gpr35,Tmeff1,D1Ertd622e,Ogfrl1 |
| 3.907e-02 | -3.24 | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN | 185 | 22 | 15632 | 1249 |
Cd34,Fcgr1,Plaur,Hmox1,Traf3ip2,C3,Grina,Cd180,Il18,H2-Aa,Ampd3,Cp,Bst1,Slc7a8,Aoah,Plod3,Syk,Ccl12,Hopx,Rgs14,Cd302,Csf3r |
| 3.907e-02 | -3.24 | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP | 185 | 22 | 15632 | 1249 |
Phlpp2,Alas1,Clec4n,Tnfrsf1b,Sesn3,Ahrr,Etnk1,Acvr1b,Azi2,Ikzf1,Parp14,Aebp2,Ogfrl1,Stk40,Gpr68,Spn,Eno1,Hvcn1,Hlx,Csrnp1,Pgm1,Ifih1 |
| 3.907e-02 | -3.24 | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | 185 | 22 | 15632 | 1249 |
Mdfic,Ppfibp2,Ccl4,Ahsa1,Il15,Rbms1,Osbpl3,Sema4a,Kif3c,Ttc39b,Dgkh,Vasp,Met,Phlpp1,Tlr1,Cish,Rab11fip1,Gpr132,Myadm,Plekha5,Dusp1,Cx3cr1 |
| 3.907e-02 | -3.24 | GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_DN | 185 | 22 | 15632 | 1249 |
Sema4a,Pttg1,Ppa1,Nfkbiz,Frmd6,Pnpt1,Hcls1,Ppp2r1b,Rnf34,Itgal,Il10,Ikbkg,Bcl2l11,Slc4a7,Dusp1,Klf3,Psat1,Stx6,Glipr2,Ly75,Sat1,Caml |
| 3.907e-02 | -3.24 | GO_PHOSPHATIDYLINOSITOL_BINDING | MSigDB lists | GO_PHOSPHATIDYLINOSITOL_BINDING | 185 | 22 | 15632 | 1249 |
Myo10,Rnf34,Sgk3,Tulp3,Cyth3,Apba1,Kcnj2,Itpr1,Plekha5,Zcchc2,Mitd1,Mppe1,Fcho2,Snx2,Slc9a1,Wdfy1,Myo1b,Plekha4,Plekha2,Adap2,Plek,Snx10 |
| 3.907e-02 | -3.24 | GSE17721_LPS_VS_CPG_24H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_CPG_24H_BMDC_DN | 185 | 22 | 15632 | 1249 |
Hck,Prdx1,Rnd3,Slc30a4,Ythdf1,Slc44a1,Trip10,Acpp,Swap70,Hcar2,Jak2,Lyn,Acvr1b,Ebi3,Tlr9,Hp,Pdss1,Tlr1,Lmo4,Il10,Slc13a3,Slc4a7 |
| 3.908e-02 | -3.24 | - | gene3d domains | 4.10.10.10 | 4 | 2 | 8819 | 755 |
Mt1,Mt2 |
| 3.908e-02 | -3.24 | - | gene3d domains | 3.30.1120.30 | 4 | 2 | 8819 | 755 |
Plk2,Plk3 |
| 3.908e-02 | -3.24 | DNA2/NAM7-like_AAA | interpro domains | IPR041679 | 11 | 3 | 19984 | 1430 |
Znfx1,Helz2,Mov10 |
| 3.908e-02 | -3.24 | SAND-like_dom_sf | interpro domains | IPR010919 | 11 | 3 | 19984 | 1430 |
Sp110,Sp140,Sp100 |
| 3.908e-02 | -3.24 | GBD/FH3_dom | interpro domains | IPR014768 | 11 | 3 | 19984 | 1430 |
Daam1,Fmnl2,Diaph2 |
| 3.908e-02 | -3.24 | Formyl_rcpt-rel | interpro domains | IPR000826 | 11 | 3 | 19984 | 1430 |
Fpr2,Fpr1,Cmklr1 |
| 3.918e-02 | -3.24 | MODULE_154 | MSigDB lists | MODULE_154 | 67 | 10 | 15632 | 1249 |
Serpine1,Adrb2,Cav1,Ptgs2,Dusp6,S100a8,B3gnt5,Mmp14,Serpinb2,Lipg |
| 3.933e-02 | -3.24 | positive regulation of DNA metabolic process | biological process | GO:0051054 | 205 | 21 | 20694 | 1406 |
Parp9,Spire1,Clcf1,Cd40,Pdgfb,Igf1r,Mecp2,Il6,Atm,Pml,Parp3,Tnfsf4,Eya4,Prdm9,Myc,Dtx3l,Timeless,Fbxo4,Sirt1,Src,Pdgfrb |
| 3.937e-02 | -3.23 | FERM_domain | interpro domains | IPR000299 | 45 | 7 | 19984 | 1430 |
Frmd4a,Myo10,Frmd6,Ezr,Ptk2,Jak2,Tyk2 |
| 3.944e-02 | -3.23 | NOD | smart domains | SM01338 | 4 | 2 | 9567 | 823 |
Notch2,Notch1 |
| 3.944e-02 | -3.23 | NODP | smart domains | SM01339 | 4 | 2 | 9567 | 823 |
Notch1,Notch2 |
| 3.947e-02 | -3.23 | GO_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS | 58 | 9 | 15632 | 1249 |
Ccl12,Ass1,Nr3c1,Edn1,Il6,Acvr1,Errfi1,Ifnb1,Ahr |
| 3.962e-02 | -3.23 | GSE2128_C57BL6_VS_NOD_THYMOCYTE_DN | MSigDB lists | GSE2128_C57BL6_VS_NOD_THYMOCYTE_DN | 175 | 21 | 15632 | 1249 |
Hhex,Tlr3,Gmppb,Cxcl10,Mthfd2,Stat2,Ddx58,Sgk3,Ppfibp1,Syk,Snx10,S100a8,Gem,Itpr1,Swap70,Rgs14,Slc15a3,Piezo1,Hspa2,Smpdl3b,Rnf19a |
| 3.962e-02 | -3.23 | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 175 | 21 | 15632 | 1249 |
Arhgef3,Cav1,Irf7,Csf3r,Plek,Klf6,Snx10,Ap3b1,Cd200r4,Rasgrp1,Trim21,Rhoq,Ddx58,Nr4a3,Casp7,Apaf1,Dnase1l3,Rbl1,Hck,Rbms1,Plcl2 |
| 3.962e-02 | -3.23 | GSE22886_CD8_VS_CD4_NAIVE_TCELL_UP | MSigDB lists | GSE22886_CD8_VS_CD4_NAIVE_TCELL_UP | 175 | 21 | 15632 | 1249 |
Psmb9,Tnfsf14,Higd1a,Ptch1,Parp8,Mecp2,Slc39a14,Stx6,Gclm,Cish,Pnp2,Plscr1,Pigv,Rars,Nck1,Crkl,Lrch3,Tlr3,Daxx,Rras2,Traf5 |
| 3.962e-02 | -3.23 | GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_UP | 175 | 21 | 15632 | 1249 |
Gca,Rgs1,Pcdh7,Dnajb2,Dio2,Itga5,Traf3ip2,Rnf139,Hhex,St3gal1,Abr,Tpx2,Phyh,Pim1,Isg20,Ddit4,Uba7,Dgka,Cenpe,Dpy19l1,Cd302 |
| 3.962e-02 | -3.23 | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP | 175 | 21 | 15632 | 1249 |
Trib3,Arg2,Ptger4,Itga4,Mcm10,Dusp5,Rgs3,Adam19,Tnfrsf8,Lcp2,Gpsm2,P4ha2,Apobec3,Slc39a14,Dusp4,Rasgrp1,Tnc,Irf4,Phgdh,Noc4l,Phlda1 |
| 3.962e-02 | -3.23 | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP | 175 | 21 | 15632 | 1249 |
Rap2c,Clec4e,Col27a1,Ap3m2,Itga5,Dck,Rcsd1,Il4ra,Stat2,Nkiras1,Atp11a,Med13,Ccng2,Trim56,Slc25a12,Kremen1,Lztfl1,Slc25a37,Ets2,Tap2,Il10 |
| 3.962e-02 | -3.23 | GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_UP | MSigDB lists | GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_UP | 175 | 21 | 15632 | 1249 |
Irf4,Myc,Ccrl2,Maff,Fam72a,Hsd17b12,Nampt,Tuba4a,Lap3,Prdx1,Batf,Ahsa1,Tnfsf10,Ripk3,Pgk1,Cdkn1a,Mcm10,Slc30a4,Tpi1,Ppa1,Ldha |
| 3.962e-02 | -3.23 | HFH4_01 | MSigDB lists | HFH4_01 | 175 | 21 | 15632 | 1249 |
Egr2,Slc44a1,Atxn7l1,Tlr1,Leng9,Ccnd1,Nfkbie,Map4k4,Klf3,Bcl6,Cited2,Bambi,Cacna1d,Zhx2,Pf4,Myo10,Crim1,H3f3b,Cpeb4,Prdm1,Nr4a3 |
| 3.962e-02 | -3.23 | GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 175 | 21 | 15632 | 1249 |
Ap3m2,Glrx,Traf5,Il18,Arrdc4,Nr4a3,Itga4,Ptprj,Prdm1,Traf3ip2,Mmd,Ampd3,Ppp2r5a,Fzd5,Il10,Cnn2,Mthfd1l,Plek,Rapgef5,Itgav,Cst7 |
| 3.967e-02 | -3.23 | RBBP6 (RB binding protein 6, ubiquitin ligase) | protein interactions | 5930 | 14 | 4 | 7778 | 753 |
Itga5,Max,Plk2,Chmp4b |
| 3.967e-02 | -3.23 | ELOB (elongin B) | protein interactions | 6923 | 14 | 4 | 7778 | 753 |
Cish,Socs1,Socs3,Socs7 |
| 3.967e-02 | -3.23 | GZMB (granzyme B) | protein interactions | 3002 | 14 | 4 | 7778 | 753 |
Notch1,Casp7,Hspa1b,Casp3 |
| 3.967e-02 | -3.23 | Smarcb1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1) | protein interactions | 20587 | 14 | 4 | 7778 | 753 |
Fos,Jun,Mecp2,Ets2 |
| 3.967e-02 | -3.23 | DDB1 (damage specific DNA binding protein 1) | protein interactions | 1642 | 14 | 4 | 7778 | 753 |
Ksr1,Cdkn1a,Brwd3,Atm |
| 3.967e-02 | -3.23 | Birc3 (baculoviral IAP repeat-containing 3) | protein interactions | 11796 | 14 | 4 | 7778 | 753 |
Myd88,Casp3,Cd40,Traf2 |
| 3.967e-02 | -3.23 | Srf (serum response factor) | protein interactions | 20807 | 14 | 4 | 7778 | 753 |
Tagln,Hopx,Edn1,Egr1 |
| 3.967e-02 | -3.23 | HIF1_Q3 | MSigDB lists | HIF1_Q3 | 206 | 24 | 15632 | 1249 |
Nfil3,Pgk1,Tsku,Gys1,Ccnd2,Gbe1,Ddx4,Max,Ldha,Lrp8,Zfp800,Psd,Pdgfb,Ddit4,Rab10,Fchsd2,Tet2,Cited2,Hmga1,Bcl6,Eno1,Pdk3,Brwd3,Bcl2l11 |
| 3.967e-02 | -3.23 | REACTOME_S_PHASE | MSigDB lists | REACTOME_S_PHASE | 105 | 14 | 15632 | 1249 |
Psmb6,Psme1,Max,Mcm6,Psmb10,Cdkn1a,Ccne1,Psmb8,Psmb9,Psmd10,Myc,Psme2,Psma6,Ccnd1 |
| 3.970e-02 | -3.23 | Intrinsic Pathway for Apoptosis | REACTOME pathways | R-MMU-109606 | 37 | 7 | 8608 | 757 |
Casp7,Bcl2l11,Casp3,Casp8,Cycs,Pmaip1,Apaf1 |
| 3.976e-02 | -3.22 | AAA_12 | pfam domains | PF13087 | 11 | 3 | 18711 | 1348 |
Znfx1,Mov10,Helz2 |
| 3.980e-02 | -3.22 | GO_MITOTIC_CELL_CYCLE | MSigDB lists | GO_MITOTIC_CELL_CYCLE | 689 | 68 | 15632 | 1249 |
Mitd1,Ppp2r2a,Smc5,Psmb6,Mcm6,Gpr132,Btg2,Phlda1,Inhba,Tuba4a,Plk2,Rrs1,Crlf3,Mcmbp,Psme1,Plk3,Ube2e1,Mcm10,Pml,Psmb10,Setdb2,Acvr1,Ccnd1,Mdm2,Ccng2,Psma6,Dync1h1,Rgs14,Psmb9,Gpsm2,Rbbp8,Birc2,Cdkn1a,Gfi1,Wdr43,Prkar2b,Pim2,Acvr1b,Azi2,Timeless,Psme2,Casp2,Rhou,Psmb8,Atm,Birc3,Ccne1,Gem,Cenpj,Hinfp,Chmp4b,Tnks1bp1,Vcpip1,Nek6,Cdkn2d,Plagl1,Pttg1,Tpx2,Abcb1a,Spry2,Katna1,Cnot4,Optn,Triobp,Cenpe,Sbds,Psmd10,Nlrc4 |
| 3.981e-02 | -3.22 | Golgi apparatus part | cellular component | GO:0044431 | 494 | 44 | 20747 | 1409 |
Atp11b,Plk3,Mgat1,Rtn1,Lpcat2,Golga3,Atp11a,Whamm,Myo1b,Irgm2,Rab10,Prkce,Pgap2,Gsap,Srgn,Plod3,Tapbp,Vps54,Rab21,Rab32,Tpst1,Cav1,Rab19,H2-Q7,Fut8,Aftph,Lap3,Arl5b,Cop1,H2-Q4,Acpp,Ap3b1,Tgfbi,H2-Q6,Arl5c,Stx6,Optn,Bcl9,Ric1,Nlrp3,Cpd,Pmepa1,Sgms2,Glipr2 |
| 3.989e-02 | -3.22 | positive regulation of osteoblast differentiation | biological process | GO:0045669 | 68 | 9 | 20694 | 1406 |
Acvr1,Bmp2,Ifi204,Jag1,Il6,Fam20c,Ptger4,Cebpd,Pdlim7 |
| 3.989e-02 | -3.22 | actin cytoskeleton reorganization | biological process | GO:0031532 | 68 | 9 | 20694 | 1406 |
S1pr2,Antxr1,Plek,Sipa1l1,Whamm,Rictor,Ezr,Micall2,Rac3 |
| 3.989e-02 | -3.22 | protein autoubiquitination | biological process | GO:0051865 | 68 | 9 | 20694 | 1406 |
Trim30a,Cnot4,Rnf19b,Trim13,Trim21,Traf2,Mdm2,Dtx3l,Bfar |
| 3.989e-02 | -3.22 | GO_REGULATION_OF_PROTEIN_POLYUBIQUITINATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_POLYUBIQUITINATION | 10 | 3 | 15632 | 1249 |
Birc2,Parp10,Nmi |
| 3.989e-02 | -3.22 | YEMELYANOV_GR_TARGETS_DN | MSigDB lists | YEMELYANOV_GR_TARGETS_DN | 10 | 3 | 15632 | 1249 |
Jun,Stat1,Egr1 |
| 3.989e-02 | -3.22 | chr21q11 | MSigDB lists | chr21q11 | 10 | 3 | 15632 | 1249 |
Samsn1,Usp25,Cnn2 |
| 3.989e-02 | -3.22 | GO_NEGATIVE_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS | 10 | 3 | 15632 | 1249 |
Bcl6,Irs2,Cd74 |
| 3.989e-02 | -3.22 | GO_ESTABLISHMENT_OF_ENDOTHELIAL_INTESTINAL_BARRIER | MSigDB lists | GO_ESTABLISHMENT_OF_ENDOTHELIAL_INTESTINAL_BARRIER | 10 | 3 | 15632 | 1249 |
F11r,Rapgef2,Rap2c |
| 3.989e-02 | -3.22 | GO_REGULATION_OF_NUCLEAR_TRANSCRIBED_MRNA_POLY_A_TAIL_SHORTENING | MSigDB lists | GO_REGULATION_OF_NUCLEAR_TRANSCRIBED_MRNA_POLY_A_TAIL_SHORTENING | 10 | 3 | 15632 | 1249 |
Zfp36,Polr2g,Btg2 |
| 3.989e-02 | -3.22 | REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES | MSigDB lists | REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES | 10 | 3 | 15632 | 1249 |
Myd88,Ripk2,Sqstm1 |
| 3.989e-02 | -3.22 | FUNG_IL2_SIGNALING_2 | MSigDB lists | FUNG_IL2_SIGNALING_2 | 10 | 3 | 15632 | 1249 |
Slc30a1,Myc,Irf4 |
| 3.989e-02 | -3.22 | BIOCARTA_PARKIN_PATHWAY | MSigDB lists | BIOCARTA_PARKIN_PATHWAY | 10 | 3 | 15632 | 1249 |
Ube2l6,Ube2f,Ube2e2 |
| 3.989e-02 | -3.22 | BIOCARTA_RNA_PATHWAY | MSigDB lists | BIOCARTA_RNA_PATHWAY | 10 | 3 | 15632 | 1249 |
Nfkb1,Eif2ak2,Nfkbia |
| 3.989e-02 | -3.22 | REACTOME_PECAM1_INTERACTIONS | MSigDB lists | REACTOME_PECAM1_INTERACTIONS | 10 | 3 | 15632 | 1249 |
Src,Itgav,Lyn |
| 3.989e-02 | -3.22 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | MSigDB lists | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | 10 | 3 | 15632 | 1249 |
Tlr3,Ikbkg,Cd14 |
| 3.989e-02 | -3.22 | GOERING_BLOOD_HDL_CHOLESTEROL_QTL_CIS | MSigDB lists | GOERING_BLOOD_HDL_CHOLESTEROL_QTL_CIS | 10 | 3 | 15632 | 1249 |
Tmem176b,Ikzf1,H2-Eb1 |
| 3.989e-02 | -3.22 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_RUNX1 | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_RUNX1 | 10 | 3 | 15632 | 1249 |
Cd55,Csf3r,Acvrl1 |
| 3.989e-02 | -3.22 | GO_REGULATION_OF_T_CELL_CHEMOTAXIS | MSigDB lists | GO_REGULATION_OF_T_CELL_CHEMOTAXIS | 10 | 3 | 15632 | 1249 |
Ccl5,Tnfsf14,Cxcl10 |
| 3.989e-02 | -3.22 | KRISHNAN_FURIN_TARGETS_UP | MSigDB lists | KRISHNAN_FURIN_TARGETS_UP | 10 | 3 | 15632 | 1249 |
Jun,H3f3b,Fos |
| 3.989e-02 | -3.22 | MIKKELSEN_PARTIALLY_REPROGRAMMED_TO_PLURIPOTENCY | MSigDB lists | MIKKELSEN_PARTIALLY_REPROGRAMMED_TO_PLURIPOTENCY | 10 | 3 | 15632 | 1249 |
Syne2,Cdkn1a,Ccnd1 |
| 3.989e-02 | -3.22 | GO_PROTEIN_PHOSPHATASE_TYPE_1_COMPLEX | MSigDB lists | GO_PROTEIN_PHOSPHATASE_TYPE_1_COMPLEX | 10 | 3 | 15632 | 1249 |
Ppp1r15b,Nck1,Ppp1r15a |
| 3.989e-02 | -3.22 | GO_THIOESTERASE_BINDING | MSigDB lists | GO_THIOESTERASE_BINDING | 10 | 3 | 15632 | 1249 |
Traf5,Traf1,Traf2 |
| 3.989e-02 | -3.22 | GO_MUSCLE_ATROPHY | MSigDB lists | GO_MUSCLE_ATROPHY | 10 | 3 | 15632 | 1249 |
Psmb9,Il15,Cflar |
| 3.989e-02 | -3.22 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | MSigDB lists | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | 10 | 3 | 15632 | 1249 |
Slc16a1,Slc16a3,Slc13a3 |
| 3.989e-02 | -3.22 | GO_PEPTIDYL_PROLINE_HYDROXYLATION | MSigDB lists | GO_PEPTIDYL_PROLINE_HYDROXYLATION | 10 | 3 | 15632 | 1249 |
Egln3,P4ha2,P4ha1 |
| 3.989e-02 | -3.22 | IIZUKA_LIVER_CANCER_EARLY_RECURRENCE | MSigDB lists | IIZUKA_LIVER_CANCER_EARLY_RECURRENCE | 10 | 3 | 15632 | 1249 |
Tnfaip3,Rel,Ccnd2 |
| 3.989e-02 | -3.22 | GO_MAINTENANCE_OF_CELL_POLARITY | MSigDB lists | GO_MAINTENANCE_OF_CELL_POLARITY | 10 | 3 | 15632 | 1249 |
Slc9a1,Pdzd11,Lhx2 |
| 3.989e-02 | -3.22 | GO_REGULATION_OF_SKELETAL_MUSCLE_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_SKELETAL_MUSCLE_CELL_PROLIFERATION | 10 | 3 | 15632 | 1249 |
Cflar,Stat3,Angpt1 |
| 3.989e-02 | -3.22 | GO_INTESTINAL_EPITHELIAL_CELL_DEVELOPMENT | MSigDB lists | GO_INTESTINAL_EPITHELIAL_CELL_DEVELOPMENT | 10 | 3 | 15632 | 1249 |
Hif1a,Cdkn1a,Prdm1 |
| 3.989e-02 | -3.22 | GO_HISTONE_MRNA_CATABOLIC_PROCESS | MSigDB lists | GO_HISTONE_MRNA_CATABOLIC_PROCESS | 10 | 3 | 15632 | 1249 |
Atm,Dcp2,Xrn1 |
| 3.989e-02 | -3.22 | GO_TOLERANCE_INDUCTION | MSigDB lists | GO_TOLERANCE_INDUCTION | 10 | 3 | 15632 | 1249 |
C3,Tnfaip3,Lyn |
| 3.989e-02 | -3.22 | GO_HEMOGLOBIN_METABOLIC_PROCESS | MSigDB lists | GO_HEMOGLOBIN_METABOLIC_PROCESS | 10 | 3 | 15632 | 1249 |
Inhba,Tet2,Hif1a |
| 3.989e-02 | -3.22 | ROZANOV_MMP14_CORRELATED | MSigDB lists | ROZANOV_MMP14_CORRELATED | 10 | 3 | 15632 | 1249 |
Jag1,Pik3cd,Nr3c1 |
| 3.989e-02 | -3.22 | GO_NEGATIVE_REGULATION_OF_BONE_RESORPTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_BONE_RESORPTION | 10 | 3 | 15632 | 1249 |
Ubash3b,Cd38,Tnfaip3 |
| 3.989e-02 | -3.22 | GO_ANION_TRANSMEMBRANE_TRANSPORTING_ATPASE_ACTIVITY | MSigDB lists | GO_ANION_TRANSMEMBRANE_TRANSPORTING_ATPASE_ACTIVITY | 10 | 3 | 15632 | 1249 |
Abcc5,Abcc1,Abcc4 |
| 4.000e-02 | -3.22 | GO_CELL_CYCLE_PROCESS | MSigDB lists | GO_CELL_CYCLE_PROCESS | 952 | 91 | 15632 | 1249 |
Ppp2r2a,Mitd1,Mcm6,Spire1,Psmb6,Inhba,Gpr132,Ppp1r15a,Map2k1,Rrs1,Psmb10,Plk3,Hspa2,Ccng2,Phgdh,Cdkn1a,Wdr43,Notch2,Ddx4,Pim2,Rhou,Psme2,Gem,Cenpj,Atm,Kat2b,Tpx2,Nek6,Cdkn2d,Cnot4,Optn,Katna1,Nlrc4,Thbs1,Il12b,Prdm9,Smc5,Btg2,Phlda1,Plk2,Tuba4a,Rhoc,Mcmbp,Crlf3,Psme1,Ube2e1,Mcm10,Pml,Acvr1,Ccnd1,Mdm2,Psma6,Setdb2,Top3a,Rgs14,Psmb9,Gpsm2,Rbbp8,Birc2,Dusp1,Dync1h1,Gfi1,Prkar2b,Acvr1b,Irf1,Casp2,Trip13,Timeless,Psmb8,Eif4g2,Birc3,Ccne1,Chmp4b,Tnks1bp1,Vcpip1,Hinfp,Pnpt1,Pttg1,Plagl1,Prnp,Sass6,Mapkapk2,Triobp,Abcb1a,Spry2,Myc,Psmd10,Ezr,Cenpe,Sbds,Bcl2l11 |
| 4.006e-02 | -3.22 | protein-containing complex subunit organization | biological process | GO:0043933 | 1540 | 122 | 20694 | 1406 |
P4ha1,Gsdmd,Malt1,Max,Lipg,Plod3,Agrn,Plod2,Cd74,Brd2,Dync1h1,Cutc,Stxbp3,Igf1r,Psip1,Pfkl,Ccl5,Jmjd6,Noct,Angpt1,Ikzf1,Pstpip2,Me1,H3f3b,Acpp,Rasgrp1,Ago3,Gch1,Pml,Denr,Gfpt1,Stxbp1,Col11a2,Snx2,Daxx,Cx3cl1,Sod2,Fcho2,Tcf4,Slc2a1,Mmp9,Pdgfc,Lrrc8c,Mlkl,Mdm2,Diaph2,Kctd12,Txnrd1,Dnaaf3,Itpr1,Gja1,Sqstm1,Dbnl,Keap1,Psmd10,Cav1,Coa5,Prnp,Prdm9,Samhd1,G3bp2,Lox,Cox18,Vasp,Plagl2,Myc,Ptk2,Homer1,Birc2,Trim21,Dgkh,Rubcnl,Fas,Tap2,Nupr1,Nod2,Pla2g7,Apaf1,Pf4,Evl,Ddit4,Sco1,Asf1a,Birc3,Cenpj,Cenpe,Mcoln2,Pnpt1,Hopx,Ehd1,Mdn1,Apba1,Zc3h12a,Optn,Pdss1,Nlrp3,Chmp4b,Mcm6,Mx1,Nlrc4,Hat1,Ripk3,Hmox1,Adar,Mx2,Cycs,Sbds,Cox17,Rrs1,Map2k1,Tapbpl,Tapbp,Hcls1,Lcn2,Micall2,Kcnj2,Marcks,Traf2,Ikbke,Kcna3,Tifa,Lrp4 |
| 4.008e-02 | -3.22 | GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP | 165 | 20 | 15632 | 1249 |
Igf1r,Zhx2,Abcc4,Znrf1,Tnfrsf8,Rnf145,Spire1,Kif3c,Rin2,Cept1,Lztfl1,Cxcl2,Itgb8,Swap70,Atp6v1d,Gem,Slc7a8,Adhfe1,Tshz1,Dhrs9 |
| 4.015e-02 | -3.22 | mouse chr16|16 C1.2 | chromosome location | mouse chr16|16 C1.2 | 13 | 3 | 24173 | 1464 |
Dcbld2,Cldnd1,St3gal6 |
| 4.015e-02 | -3.22 | ripoptosome | cellular component | GO:0097342 | 5 | 2 | 20747 | 1409 |
Cflar,Casp8 |
| 4.015e-02 | -3.22 | sorting endosome | cellular component | GO:0097443 | 5 | 2 | 20747 | 1409 |
Ldlr,Kdr |
| 4.015e-02 | -3.22 | platelet dense tubular network | cellular component | GO:0031094 | 5 | 2 | 20747 | 1409 |
Itpr1,Ehd1 |
| 4.015e-02 | -3.22 | phosphopyruvate hydratase complex | cellular component | GO:0000015 | 5 | 2 | 20747 | 1409 |
Eno1,Eno2 |
| 4.015e-02 | -3.22 | IPAF inflammasome complex | cellular component | GO:0072557 | 5 | 2 | 20747 | 1409 |
Nlrc4,Casp1 |
| 4.018e-02 | -3.21 | negative regulation of NLRP3 inflammasome complex assembly | biological process | GO:1900226 | 5 | 2 | 20694 | 1406 |
Trim30a,Mefv |
| 4.018e-02 | -3.21 | mesangial cell differentiation | biological process | GO:0072007 | 5 | 2 | 20694 | 1406 |
Pdgfb,Notch1 |
| 4.018e-02 | -3.21 | negative regulation of alkaline phosphatase activity | biological process | GO:0010693 | 5 | 2 | 20694 | 1406 |
Ahr,Tnf |
| 4.018e-02 | -3.21 | innate immune response activating cell surface receptor signaling pathway | biological process | GO:0002220 | 5 | 2 | 20694 | 1406 |
Klrk1,Tlr2 |
| 4.018e-02 | -3.21 | mesangial cell development | biological process | GO:0072143 | 5 | 2 | 20694 | 1406 |
Notch1,Pdgfb |
| 4.018e-02 | -3.21 | malate-aspartate shuttle | biological process | GO:0043490 | 5 | 2 | 20694 | 1406 |
Slc25a12,Slc25a22 |
| 4.018e-02 | -3.21 | negative regulation of CD8-positive, alpha-beta T cell activation | biological process | GO:2001186 | 5 | 2 | 20694 | 1406 |
Cd274,Socs1 |
| 4.018e-02 | -3.21 | regulation of NK T cell proliferation | biological process | GO:0051140 | 5 | 2 | 20694 | 1406 |
Il18,Il12b |
| 4.018e-02 | -3.21 | regulation of type II hypersensitivity | biological process | GO:0002892 | 5 | 2 | 20694 | 1406 |
Fcgr1,C3 |
| 4.018e-02 | -3.21 | negative regulation of pinocytosis | biological process | GO:0048550 | 5 | 2 | 20694 | 1406 |
Cav1,Nr1h3 |
| 4.018e-02 | -3.21 | negative regulation of glial cell migration | biological process | GO:1903976 | 5 | 2 | 20694 | 1406 |
Fas,Stap1 |
| 4.018e-02 | -3.21 | regulation of growth hormone receptor signaling pathway | biological process | GO:0060398 | 5 | 2 | 20694 | 1406 |
Jak2,Gdf15 |
| 4.018e-02 | -3.21 | sperm mitochondrion organization | biological process | GO:0030382 | 5 | 2 | 20694 | 1406 |
Ddhd1,Nectin2 |
| 4.018e-02 | -3.21 | positive regulation of spindle assembly | biological process | GO:1905832 | 5 | 2 | 20694 | 1406 |
Gpsm2,Dync1h1 |
| 4.018e-02 | -3.21 | establishment of Sertoli cell barrier | biological process | GO:0097368 | 5 | 2 | 20694 | 1406 |
Arid4a,Icam1 |
| 4.018e-02 | -3.21 | cellular response to corticotropin-releasing hormone stimulus | biological process | GO:0071376 | 5 | 2 | 20694 | 1406 |
Nr4a1,Nr4a3 |
| 4.018e-02 | -3.21 | positive regulation of cell adhesion molecule production | biological process | GO:0060355 | 5 | 2 | 20694 | 1406 |
Cav1,Glrx |
| 4.018e-02 | -3.21 | regulation of peptidyl-serine dephosphorylation | biological process | GO:1902308 | 5 | 2 | 20694 | 1406 |
Ppp1r15a,Swap70 |
| 4.018e-02 | -3.21 | regulation of isomerase activity | biological process | GO:0010911 | 5 | 2 | 20694 | 1406 |
Plscr1,Nod2 |
| 4.018e-02 | -3.21 | myeloid cell apoptotic process | biological process | GO:0033028 | 5 | 2 | 20694 | 1406 |
Hcar2,Il6 |
| 4.018e-02 | -3.21 | negative regulation of interferon-gamma secretion | biological process | GO:1902714 | 5 | 2 | 20694 | 1406 |
Zc3h12a,Lgals9 |
| 4.018e-02 | -3.21 | leukotriene signaling pathway | biological process | GO:0061737 | 5 | 2 | 20694 | 1406 |
Rgs1,Cysltr2 |
| 4.018e-02 | -3.21 | positive regulation of female gonad development | biological process | GO:2000196 | 5 | 2 | 20694 | 1406 |
Src,Ptger4 |
| 4.018e-02 | -3.21 | positive regulation of isomerase activity | biological process | GO:0010912 | 5 | 2 | 20694 | 1406 |
Plscr1,Nod2 |
| 4.018e-02 | -3.21 | cell adhesion involved in heart morphogenesis | biological process | GO:0061343 | 5 | 2 | 20694 | 1406 |
Acvr1,Flrt2 |
| 4.018e-02 | -3.21 | dentinogenesis | biological process | GO:0097187 | 5 | 2 | 20694 | 1406 |
Fam20c,Serpine1 |
| 4.018e-02 | -3.21 | negative regulation of cardiac muscle contraction | biological process | GO:0055118 | 5 | 2 | 20694 | 1406 |
Zc3h12a,Pde5a |
| 4.018e-02 | -3.21 | regulation of interferon-beta secretion | biological process | GO:0035547 | 5 | 2 | 20694 | 1406 |
Ddx58,Ifih1 |
| 4.018e-02 | -3.21 | positive regulation of type II hypersensitivity | biological process | GO:0002894 | 5 | 2 | 20694 | 1406 |
C3,Fcgr1 |
| 4.018e-02 | -3.21 | cytoplasmic pattern recognition receptor signaling pathway in response to virus | biological process | GO:0039528 | 5 | 2 | 20694 | 1406 |
Ifih1,Ddx58 |
| 4.018e-02 | -3.21 | oxygen homeostasis | biological process | GO:0032364 | 5 | 2 | 20694 | 1406 |
Sod2,Hif1a |
| 4.018e-02 | -3.21 | positive regulation of B cell apoptotic process | biological process | GO:0002904 | 5 | 2 | 20694 | 1406 |
Il10,Myc |
| 4.018e-02 | -3.21 | corticosteroid receptor signaling pathway | biological process | GO:0031958 | 5 | 2 | 20694 | 1406 |
Nr3c1,Jak2 |
| 4.018e-02 | -3.21 | cellular response to interleukin-12 | biological process | GO:0071349 | 5 | 2 | 20694 | 1406 |
Jak2,Il12rb1 |
| 4.018e-02 | -3.21 | negative regulation of MHC class II biosynthetic process | biological process | GO:0045347 | 5 | 2 | 20694 | 1406 |
Pf4,Il10 |
| 4.018e-02 | -3.21 | T cell antigen processing and presentation | biological process | GO:0002457 | 5 | 2 | 20694 | 1406 |
Treml4,Icam1 |
| 4.018e-02 | -3.21 | maintenance of lens transparency | biological process | GO:0036438 | 5 | 2 | 20694 | 1406 |
Chmp4b,Gcnt2 |
| 4.018e-02 | -3.21 | positive regulation of immature T cell proliferation | biological process | GO:0033091 | 5 | 2 | 20694 | 1406 |
Il1b,Ripk2 |
| 4.018e-02 | -3.21 | negative regulation of isotype switching | biological process | GO:0045829 | 5 | 2 | 20694 | 1406 |
Bcl6,Parp3 |
| 4.018e-02 | -3.21 | positive regulation of interferon-beta secretion | biological process | GO:0035549 | 5 | 2 | 20694 | 1406 |
Ddx58,Ifih1 |
| 4.018e-02 | -3.21 | response to corticotropin-releasing hormone | biological process | GO:0043435 | 5 | 2 | 20694 | 1406 |
Nr4a3,Nr4a1 |
| 4.018e-02 | -3.21 | interleukin-3-mediated signaling pathway | biological process | GO:0038156 | 5 | 2 | 20694 | 1406 |
Csf3r,Syk |
| 4.018e-02 | -3.21 | maintenance of permeability of blood-brain barrier | biological process | GO:0035633 | 5 | 2 | 20694 | 1406 |
Ptgs2,Abcb1a |
| 4.018e-02 | -3.21 | negative regulation of mitochondrial fusion | biological process | GO:0010637 | 5 | 2 | 20694 | 1406 |
Mul1,Bnip3 |
| 4.018e-02 | -3.21 | soft palate development | biological process | GO:0060023 | 5 | 2 | 20694 | 1406 |
Col11a2,Tshz1 |
| 4.018e-02 | -3.21 | negative regulation of vitamin D biosynthetic process | biological process | GO:0010957 | 5 | 2 | 20694 | 1406 |
Gfi1,Nfkb1 |
| 4.018e-02 | -3.21 | regulation of entry of bacterium into host cell | biological process | GO:2000535 | 5 | 2 | 20694 | 1406 |
Cav1,Itgav |
| 4.018e-02 | -3.21 | positive regulation of type IIa hypersensitivity | biological process | GO:0001798 | 5 | 2 | 20694 | 1406 |
C3,Fcgr1 |
| 4.018e-02 | -3.21 | cellular response to nicotine | biological process | GO:0071316 | 5 | 2 | 20694 | 1406 |
Nfkb1,Tnf |
| 4.018e-02 | -3.21 | negative regulation of interferon-alpha production | biological process | GO:0032687 | 5 | 2 | 20694 | 1406 |
Nmi,Gbp4 |
| 4.018e-02 | -3.21 | growth involved in heart morphogenesis | biological process | GO:0003241 | 5 | 2 | 20694 | 1406 |
Ahr,Notch1 |
| 4.018e-02 | -3.21 | regulation of type IIa hypersensitivity | biological process | GO:0001796 | 5 | 2 | 20694 | 1406 |
C3,Fcgr1 |
| 4.018e-02 | -3.21 | positive regulation of antimicrobial humoral response | biological process | GO:0002760 | 5 | 2 | 20694 | 1406 |
Acod1,Nod2 |
| 4.018e-02 | -3.21 | toll-like receptor 2 signaling pathway | biological process | GO:0034134 | 5 | 2 | 20694 | 1406 |
Tlr2,Ripk2 |
| 4.018e-02 | -3.21 | drug export | biological process | GO:0046618 | 5 | 2 | 20694 | 1406 |
Abcc1,Abcb1a |
| 4.018e-02 | -3.21 | positive regulation of neutrophil apoptotic process | biological process | GO:0033031 | 5 | 2 | 20694 | 1406 |
Hcar2,Pik3cd |
| 4.018e-02 | -3.21 | TRIF-dependent toll-like receptor signaling pathway | biological process | GO:0035666 | 5 | 2 | 20694 | 1406 |
Cd300lf,Tlr6 |
| 4.018e-02 | -3.21 | regulation of mast cell apoptotic process | biological process | GO:0033025 | 5 | 2 | 20694 | 1406 |
Kitl,Stat5a |
| 4.018e-02 | -3.21 | negative regulation of defense response to bacterium | biological process | GO:1900425 | 5 | 2 | 20694 | 1406 |
Arg2,Mapkbp1 |
| 4.028e-02 | -3.21 | GO_POSITIVE_REGULATION_OF_BLOOD_CIRCULATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_BLOOD_CIRCULATION | 86 | 12 | 15632 | 1249 |
Cd38,Htr2a,Icam1,Kat2b,Ptgs2,Adrb2,Ptafr,Hmox1,Edn1,Cav1,Nos2,Gja1 |
| 4.031e-02 | -3.21 | GO_PROTEIN_PHOSPHATASE_BINDING | MSigDB lists | GO_PROTEIN_PHOSPHATASE_BINDING | 115 | 15 | 15632 | 1249 |
Irs2,Sphk1,Smg7,Mvp,Ppp2r2a,Atp2b4,Stau1,Ppp6r1,Ppp1r15a,Traf2,Stat3,Slc9a1,Phactr4,Met,Ap3b1 |
| 4.031e-02 | -3.21 | GO_CARBOHYDRATE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_CARBOHYDRATE_BIOSYNTHETIC_PROCESS | 115 | 15 | 15632 | 1249 |
Fut8,Ext1,Pcx,Slc25a12,Chst11,Eno2,Eno1,Slc2a1,Gys1,Pgk1,Tpi1,Atf3,Gpd2,Gbe1,Pgm1 |
| 4.031e-02 | -3.21 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_UP | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_UP | 115 | 15 | 15632 | 1249 |
Reps1,Zscan29,Src,Fam43a,Ctu1,Gna15,Cd40,Rrs1,Sdc4,Xcr1,Hhex,Kif5c,Aida,Adora2b,Arrdc4 |
| 4.041e-02 | -3.21 | CTATGCA_MIR153 | MSigDB lists | CTATGCA_MIR153 | 196 | 23 | 15632 | 1249 |
Rai14,Src,Morc3,Znfx1,Cited2,Sgk3,Clcn5,Dcp2,Arl4a,Cnn3,Ddit4,Ext1,Pdlim7,Jag1,Sh3bp4,Mier3,Dach1,Mfap3l,Flrt2,Ptch1,Zcchc2,Adam19,Larp1 |
| 4.041e-02 | -3.21 | AAGCAAT_MIR137 | MSigDB lists | AAGCAAT_MIR137 | 196 | 23 | 15632 | 1249 |
Phlpp2,Med13,Rims3,Flrt2,Fmnl2,Dio2,Rap2c,Dr1,Rsbn1,Rpgrip1l,Rcn1,Fndc3a,Ccng2,Egr2,Dusp8,Rab21,Serp1,Ptpn2,Flrt3,Plagl2,Mapkapk2,St3gal3,Prdm1 |
| 4.044e-02 | -3.21 | BROWNE_HCMV_INFECTION_18HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_18HR_DN | 155 | 19 | 15632 | 1249 |
Socs1,Psmb10,Angpt1,Atp2b4,Thbs1,Cdc42ep2,Gng11,Tnip1,Pdgfrb,Dusp1,Axl,Etv6,Triobp,Rbpms,Vcan,Rin2,Myc,Pdpn,Ext1 |
| 4.044e-02 | -3.21 | GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_UP | MSigDB lists | GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_UP | 155 | 19 | 15632 | 1249 |
Dusp6,Ppp1r14b,Casp1,Hk1,C1rl,Dmwd,Lmo4,Lap3,Tmem171,Nat2,Il12rb1,Ripk2,Denr,Dcp2,Tapbpl,Adam19,Slc48a1,Ppfibp2,Gfi1 |
| 4.045e-02 | -3.21 | Apoptosis | REACTOME pathways | R-MMU-109581 | 96 | 14 | 8608 | 757 |
Casp7,Birc2,Tnfsf10,Casp3,Traf2,Cflar,Dbnl,Fas,Ptk2,Casp8,Cycs,Pmaip1,Apaf1,Bcl2l11 |
| 4.047e-02 | -3.21 | positive regulation of chromatin organization | biological process | GO:1905269 | 112 | 13 | 20694 | 1406 |
Resf1,Sirt1,Lif,Mecp2,Atm,Bcl6,Daxx,Arid5a,Nsd3,Jdp2,Pml,Kat2b,Jarid2 |
| 4.068e-02 | -3.20 | MYC_UP.V1_DN | MSigDB lists | MYC_UP.V1_DN | 145 | 18 | 15632 | 1249 |
Cxcl2,Pcx,Rnf19a,Trim56,Il6,Bcl9,Plekha2,Map3k6,S100a8,Adhfe1,Plat,Tnfaip2,Gbp2b,Irak2,Tlr2,Il18,Mmp9,Asap3 |
| 4.068e-02 | -3.20 | GO_GASTRULATION | MSigDB lists | GO_GASTRULATION | 145 | 18 | 15632 | 1249 |
Col4a2,Mmp9,Itga5,Dusp5,Hhex,Itga4,Kdm6b,Nr4a3,Mmp14,Dusp2,Ext1,Dusp4,Inhba,Acvr1,Txnrd1,Itgav,Dusp1,Ets2 |
| 4.074e-02 | -3.20 | SOCS_box | interpro domains | IPR001496 | 36 | 6 | 19984 | 1430 |
Socs3,Socs1,Cish,Asb13,Spsb1,Socs7 |
| 4.082e-02 | -3.20 | Sushi_SCR_CCP_dom | interpro domains | IPR000436 | 55 | 8 | 19984 | 1430 |
Vcan,Il15ra,Sele,Sell,Cd55,Hp,Susd6,C1ra |
| 4.082e-02 | -3.20 | Sushi/SCR/CCP_sf | interpro domains | IPR035976 | 55 | 8 | 19984 | 1430 |
Sele,Sell,Il15ra,Vcan,C1ra,Susd6,Hp,Cd55 |
| 4.084e-02 | -3.20 | Switching of origins to a post-replicative state | REACTOME pathways | R-MMU-69052 | 70 | 11 | 8608 | 757 |
Mcm6,Psmb9,Psmb8,Psmb10,Cdkn1a,Psmb6,Psme2,Psma6,Psmd10,Psme1,Psme2b |
| 4.084e-02 | -3.20 | Orc1 removal from chromatin | REACTOME pathways | R-MMU-68949 | 70 | 11 | 8608 | 757 |
Psmb10,Cdkn1a,Mcm6,Psmb8,Psmb9,Psme1,Psmd10,Psme2b,Psme2,Psmb6,Psma6 |
| 4.096e-02 | -3.20 | miRNA binding | molecular function | GO:0035198 | 28 | 5 | 20217 | 1400 |
Pnpt1,Tut7,Zc3h12a,Ago3,Zc3h7a |
| 4.096e-02 | -3.20 | protein-lipid complex binding | molecular function | GO:0071814 | 28 | 5 | 20217 | 1400 |
Scarf1,Lrp8,Ldlr,Msr1,Thbs1 |
| 4.096e-02 | -3.20 | chemorepellent activity | molecular function | GO:0045499 | 28 | 5 | 20217 | 1400 |
Sema4c,Flrt2,Sema3c,Sema4a,Flrt3 |
| 4.096e-02 | -3.20 | lipoprotein particle binding | molecular function | GO:0071813 | 28 | 5 | 20217 | 1400 |
Msr1,Ldlr,Thbs1,Scarf1,Lrp8 |
| 4.103e-02 | -3.19 | regulation of cardiac muscle tissue development | biological process | GO:0055024 | 101 | 12 | 20694 | 1406 |
Bmp2,Sav1,Notch1,Trip10,Jarid2,Sirt1,Tomm70a,Nr3c1,Pim1,Edn1,Gja1,Cited2 |
| 4.106e-02 | -3.19 | establishment of protein localization | biological process | GO:0045184 | 1309 | 105 | 20694 | 1406 |
Ehd1,Fchsd2,Tspo,Rab11fip1,Aim2,Ap3b1,Mcoln2,Kif5c,Cenpe,Rab21,D1Ertd622e,Hinfp,Nfkbia,Arrdc4,Nod2,Tap2,Dennd1b,Stau1,Stx6,Rab3ip,Rnf19b,Vps54,Svbp,Dtx3l,Rhbdf2,Arl4a,Nos2,Rilpl1,Snx10,Hap1,Stx11,Rrs1,Sec24a,Nxf1,Myo1b,Stat3,Aftph,Tnfaip3,Fam53c,Tlr2,Adar,Rab19,Nlrc4,Lcp2,Tlr6,Plekhf2,Notch1,Nlrp3,Ranbp2,Chmp4b,Pou2f2,Optn,Tomm70a,Apba1,Rffl,Snx2,Syk,Ric1,Stxbp1,Egr2,Pml,Cdkn1a,Ift57,Arl5c,Serp1,Ikzf1,Rtn2,Rab20,Notch2,Calcrl,Hk1,Rab10,Rabgef1,Arl5b,Phip,Stxbp3,Msr1,Dennd2a,Cd74,Il1rn,Traf3ip2,Tbc1d1,Ift22,Cox18,Kpna3,Ap3m2,Rrbp1,Grk3,Trem1,Plek,Rab9,Slc15a3,Lyn,Spire1,Parp11,Tbc1d13,Hk2,Rab32,Itgav,Rtp4,Tap1,Isg15,Hhex,Arf4,Mdm2 |
| 4.106e-02 | -3.19 | cell projection morphogenesis | biological process | GO:0048858 | 482 | 43 | 20694 | 1406 |
Cnp,Sema4a,Sdc2,Map2k1,Dock10,Nrp2,Sema3c,Map4k4,Lhx2,Evl,Vasp,Lrp4,Snx2,Adora2a,Dst,Scn1b,Cyfip1,Nes,Kif5c,Stxbp1,Kdr,Egr2,Ptk2,Agrn,Notch1,Itga4,Actb,Palld,Uchl1,Klf7,Flrt2,Rab10,Lrp8,Nr4a3,Cdk5r1,Dbnl,Igf1r,Ptch1,Tsku,Gja1,Ntng2,Ext1,Flrt3 |
| 4.108e-02 | -3.19 | SH3_1 | pfam domains | PF00018 | 106 | 13 | 18711 | 1348 |
Hcls1,Fchsd2,Hck,Src,Lyn,Fgr,Sh3bp4,Fnbp1l,Trip10,Sla,Spata13,Nck1,Crkl |
| 4.110e-02 | -3.19 | Response to metal ions | REACTOME pathways | R-MMU-5660526 | 4 | 2 | 8608 | 757 |
Mt1,Mt2 |
| 4.110e-02 | -3.19 | Metal sequestration by antimicrobial proteins | REACTOME pathways | R-MMU-6799990 | 4 | 2 | 8608 | 757 |
S100a8,Lcn2 |
| 4.110e-02 | -3.19 | TP53 Regulates Transcription of Caspase Activators and Caspases | REACTOME pathways | R-MMU-6803207 | 4 | 2 | 8608 | 757 |
Casp2,Atm |
| 4.110e-02 | -3.19 | Interleukin-12 signaling | REACTOME pathways | R-MMU-447115 | 4 | 2 | 8608 | 757 |
Il12b,Il12rb1 |
| 4.110e-02 | -3.19 | Scavenging by Class F Receptors | REACTOME pathways | R-MMU-3000484 | 4 | 2 | 8608 | 757 |
Scarf1,Hsph1 |
| 4.110e-02 | -3.19 | Dectin-2 family | REACTOME pathways | R-MMU-5621480 | 4 | 2 | 8608 | 757 |
Syk,Clec4n |
| 4.110e-02 | -3.19 | FasL/ CD95L signaling | REACTOME pathways | R-MMU-75157 | 4 | 2 | 8608 | 757 |
Fas,Casp8 |
| 4.110e-02 | -3.19 | PTK6 Activates STAT3 | REACTOME pathways | R-MMU-8849474 | 4 | 2 | 8608 | 757 |
Stat3,Socs3 |
| 4.110e-02 | -3.19 | Metallothioneins bind metals | REACTOME pathways | R-MMU-5661231 | 4 | 2 | 8608 | 757 |
Mt1,Mt2 |
| 4.111e-02 | -3.19 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN | 186 | 22 | 15632 | 1249 |
Prdx1,Sgcb,Batf,Sdc4,Rnf34,Tpi1,Ggct,D1Ertd622e,Pnp2,Cox17,Psma6,P4ha2,Cldnd1,Asf1a,Stip1,Stard7,Ell2,Mthfd2,Hat1,Birc3,Psmb8,Higd1a |
| 4.111e-02 | -3.19 | GO_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS | 186 | 22 | 15632 | 1249 |
Pde5a,Adora2a,Ddit4,Edn1,Stat3,P2ry13,Nos2,Pid1,Ednrb,Me1,Pf4,Htr2a,Tspo,Thbs1,Cxcl10,Adrb2,Hif1a,Adora2b,Calcrl,Lpar1,Ptgir,Ptger4 |
| 4.111e-02 | -3.19 | GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN | 186 | 22 | 15632 | 1249 |
Rnaset2b,Trafd1,Abcc4,Polr2g,Notch2,Cutc,Mppe1,Slc30a1,Phlpp1,Stat4,Rsad2,Ccng2,Nr3c1,Stard5,Itgb8,Slc44a1,Ppm1k,Fos,Rnaset2a,Parp8,Bcl2l11,Csrp1 |
| 4.111e-02 | -3.19 | GSE28726_NAIVE_VS_ACTIVATED_VA24NEG_NKTCELL_UP | MSigDB lists | GSE28726_NAIVE_VS_ACTIVATED_VA24NEG_NKTCELL_UP | 186 | 22 | 15632 | 1249 |
Ccdc86,Pnp2,Cox17,Rsad2,Psma6,Hivep2,Srm,Eno1,Prdx1,Slc16a1,Sla,Wars,Spint2,Txn1,Nfkb1,Hopx,Lcp2,Rrs1,Osbpl3,Ccl4,Dusp5,Nsmaf |
| 4.111e-02 | -3.19 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_DN | 186 | 22 | 15632 | 1249 |
Ell2,Nsmaf,Tpx2,Hif1a,Rap2c,Nfxl1,Rsbn1,Armc8,Olr1,Dio2,Enpp4,Srm,Ctu1,Gja1,Hsph1,Rrs1,Setdb2,Reps1,Samd9l,Nqo1,Acvrl1,Jag1 |
| 4.119e-02 | -3.19 | organic acid binding | molecular function | GO:0043177 | 226 | 23 | 20217 | 1400 |
Layn,Siglece,Stard5,Plod3,S100a8,Hdc,Ass1,Sele,Sesn3,Vcan,Phyh,P4ha1,Egln3,Plod2,Fabp7,Gclc,Pcx,Gfpt1,P4ha2,Hmgcs1,Rars,Fabp3,Nos2 |
| 4.130e-02 | -3.19 | GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 444 | 46 | 15632 | 1249 |
Cx3cr1,Il6,Edn1,Triobp,Scarf1,Pde5a,S1pr2,Lrp8,Mul1,Cx3cl1,Kat2b,Tspo,Mark2,P2ry2,Zeb1,Spen,Csf1,Mmd,Rac3,Lyn,Lpar1,Trib1,Clcf1,Bcl6,Tcf4,Rgs14,Rab21,Gpr68,Glipr2,Lif,Pml,Sphk1,Hif1a,Bmp2,Etv5,Notch1,Ccl5,Myadm,Map2k1,Scn1b,Hap1,Rapgef2,Gcnt2,Bambi,Il1b,Vegfc |
| 4.141e-02 | -3.18 | positive regulation of glial cell differentiation | biological process | GO:0045687 | 58 | 8 | 20694 | 1406 |
Bmp2,Il1b,Clcf1,Notch1,Tlr2,Hdac1,Lif,Tnfrsf1b |
| 4.146e-02 | -3.18 | cellular response to glucose starvation | biological process | GO:0042149 | 38 | 6 | 20694 | 1406 |
Slc2a1,Zc3h12a,Asns,Higd1a,Sesn3,Cpeb4 |
| 4.146e-02 | -3.18 | mammary gland duct morphogenesis | biological process | GO:0060603 | 38 | 6 | 20694 | 1406 |
Pml,Kdm5b,Csf1,Nr3c1,Src,Ptch1 |
| 4.146e-02 | -3.18 | lamellipodium assembly | biological process | GO:0030032 | 38 | 6 | 20694 | 1406 |
P2ry12,Carmil1,Spata13,Nck1,Cyfip1,Whamm |
| 4.146e-02 | -3.18 | positive regulation of synaptic transmission, glutamatergic | biological process | GO:0051968 | 38 | 6 | 20694 | 1406 |
Kmo,Ptgs2,Adora2a,Stxbp1,Ccl2,Nlgn2 |
| 4.146e-02 | -3.18 | maintenance of protein localization in organelle | biological process | GO:0072595 | 38 | 6 | 20694 | 1406 |
Pml,Morc3,Tspo,Hk1,Txn1,Hk2 |
| 4.161e-02 | -3.18 | GO_POSITIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 96 | 13 | 15632 | 1249 |
Thbs1,Polr2g,Zc3h12a,Larp1,Nck1,Nsmaf,Ptafr,Il6,Ythdf1,Ccl5,Tnf,Serp1,Ppp1r15a |
| 4.163e-02 | -3.18 | E-box binding | molecular function | GO:0070888 | 47 | 7 | 20217 | 1400 |
Hdac1,Myc,Zeb1,Hif1a,Tcf4,Ahr,Max |
| 4.163e-02 | -3.18 | interleukin-12 receptor binding | molecular function | GO:0005143 | 5 | 2 | 20217 | 1400 |
Jak2,Il12rb1 |
| 4.163e-02 | -3.18 | unmethylated CpG binding | molecular function | GO:0045322 | 5 | 2 | 20217 | 1400 |
Mecp2,Tlr9 |
| 4.163e-02 | -3.18 | cyclohydrolase activity | molecular function | GO:0019238 | 5 | 2 | 20217 | 1400 |
Mthfd2,Gch1 |
| 4.163e-02 | -3.18 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | molecular function | GO:0046934 | 5 | 2 | 20217 | 1400 |
Pik3r6,Pik3cd |
| 4.163e-02 | -3.18 | double-stranded methylated DNA binding | molecular function | GO:0010385 | 5 | 2 | 20217 | 1400 |
Mecp2,Egr1 |
| 4.163e-02 | -3.18 | superoxide dismutase activity | molecular function | GO:0004784 | 5 | 2 | 20217 | 1400 |
Sod2,Nqo1 |
| 4.163e-02 | -3.18 | phosphatidylinositol bisphosphate kinase activity | molecular function | GO:0052813 | 5 | 2 | 20217 | 1400 |
Pik3r6,Pik3cd |
| 4.163e-02 | -3.18 | eukaryotic initiation factor eIF2 binding | molecular function | GO:0071074 | 5 | 2 | 20217 | 1400 |
Nck1,Myc |
| 4.163e-02 | -3.18 | growth hormone receptor binding | molecular function | GO:0005131 | 5 | 2 | 20217 | 1400 |
Jak2,Tyk2 |
| 4.163e-02 | -3.18 | procollagen-proline 4-dioxygenase activity | molecular function | GO:0004656 | 5 | 2 | 20217 | 1400 |
P4ha2,P4ha1 |
| 4.163e-02 | -3.18 | C3HC4-type RING finger domain binding | molecular function | GO:0055131 | 5 | 2 | 20217 | 1400 |
Hspa1a,Dnaja1 |
| 4.163e-02 | -3.18 | oxidoreductase activity, acting on superoxide radicals as acceptor | molecular function | GO:0016721 | 5 | 2 | 20217 | 1400 |
Nqo1,Sod2 |
| 4.163e-02 | -3.18 | phosphopyruvate hydratase activity | molecular function | GO:0004634 | 5 | 2 | 20217 | 1400 |
Eno2,Eno1 |
| 4.163e-02 | -3.18 | Rap guanyl-nucleotide exchange factor activity | molecular function | GO:0017034 | 5 | 2 | 20217 | 1400 |
Rapgef5,Rapgef2 |
| 4.167e-02 | -3.18 | GO_POSITIVE_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_ACTIVITY | 17 | 4 | 15632 | 1249 |
Gch1,Nod1,Htr2b,Hif1a |
| 4.167e-02 | -3.18 | NIELSEN_SYNOVIAL_SARCOMA_DN | MSigDB lists | NIELSEN_SYNOVIAL_SARCOMA_DN | 17 | 4 | 15632 | 1249 |
Ifi35,Parp14,Casp1,Nupr1 |
| 4.167e-02 | -3.18 | SU_THYMUS | MSigDB lists | SU_THYMUS | 17 | 4 | 15632 | 1249 |
Rhoh,Irf4,Pik3cd,Irf8 |
| 4.167e-02 | -3.18 | GO_AMIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_AMIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 17 | 4 | 15632 | 1249 |
Slc15a3,Tap2,Tapbp,Tap1 |
| 4.167e-02 | -3.18 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | MSigDB lists | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | 17 | 4 | 15632 | 1249 |
Gsr,Glrx,Txnrd1,Txn1 |
| 4.167e-02 | -3.18 | GO_CELLULAR_RESPONSE_TO_PH | MSigDB lists | GO_CELLULAR_RESPONSE_TO_PH | 17 | 4 | 15632 | 1249 |
Hvcn1,Gpr68,Nox1,Slc9a1 |
| 4.167e-02 | -3.18 | GO_PROTEIN_PHOSPHATASE_TYPE_2A_COMPLEX | MSigDB lists | GO_PROTEIN_PHOSPHATASE_TYPE_2A_COMPLEX | 17 | 4 | 15632 | 1249 |
Cycs,Ppp2r5a,Ppp2r2a,Ppp2r3a |
| 4.167e-02 | -3.18 | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN | MSigDB lists | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN | 17 | 4 | 15632 | 1249 |
Trib3,Acvr1,Nupr1,Ralgds |
| 4.167e-02 | -3.18 | GO_MACROPHAGE_DIFFERENTIATION | MSigDB lists | GO_MACROPHAGE_DIFFERENTIATION | 17 | 4 | 15632 | 1249 |
Mmp9,Csf1,Casp8,Sirt1 |
| 4.167e-02 | -3.18 | SMID_BREAST_CANCER_LUMINAL_A_DN | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_A_DN | 17 | 4 | 15632 | 1249 |
Tpx2,Slc7a5,Lrp8,Ccne1 |
| 4.167e-02 | -3.18 | GO_MATURE_B_CELL_DIFFERENTIATION | MSigDB lists | GO_MATURE_B_CELL_DIFFERENTIATION | 17 | 4 | 15632 | 1249 |
Notch2,Plcl2,Malt1,Pou2f2 |
| 4.167e-02 | -3.18 | SMID_BREAST_CANCER_RELAPSE_IN_LUNG_UP | MSigDB lists | SMID_BREAST_CANCER_RELAPSE_IN_LUNG_UP | 17 | 4 | 15632 | 1249 |
Clic4,Uchl1,Mmp14,Slc7a5 |
| 4.167e-02 | -3.18 | BOYAULT_LIVER_CANCER_SUBCLASS_G6_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G6_DN | 17 | 4 | 15632 | 1249 |
Sdc4,Inpp1,Ldlr,Tnfsf10 |
| 4.167e-02 | -3.18 | KANG_DOXORUBICIN_RESISTANCE_DN | MSigDB lists | KANG_DOXORUBICIN_RESISTANCE_DN | 17 | 4 | 15632 | 1249 |
Clic4,Psat1,Cebpd,Crim1 |
| 4.167e-02 | -3.18 | REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 | MSigDB lists | REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 | 17 | 4 | 15632 | 1249 |
Mapkapk2,Dcp2,Xrn1,Dcp1a |
| 4.167e-02 | -3.18 | WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_DN | MSigDB lists | WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_DN | 17 | 4 | 15632 | 1249 |
H2-Aa,H2-Q4,H2-Q7,H2-Q6 |
| 4.167e-02 | -3.18 | GO_REGULATION_OF_HYDROGEN_PEROXIDE_INDUCED_CELL_DEATH | MSigDB lists | GO_REGULATION_OF_HYDROGEN_PEROXIDE_INDUCED_CELL_DEATH | 17 | 4 | 15632 | 1249 |
Nr4a3,Met,Txn1,Hsph1 |
| 4.167e-02 | -3.18 | GO_NEGATIVE_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS | 17 | 4 | 15632 | 1249 |
Gfi1,Plek,Bmp2,Nfkb1 |
| 4.167e-02 | -3.18 | ZEMBUTSU_SENSITIVITY_TO_MITOMYCIN | MSigDB lists | ZEMBUTSU_SENSITIVITY_TO_MITOMYCIN | 17 | 4 | 15632 | 1249 |
Rnd3,Arhgap26,Traf2,Tnfrsf14 |
| 4.167e-02 | -3.18 | BIOCARTA_41BB_PATHWAY | MSigDB lists | BIOCARTA_41BB_PATHWAY | 17 | 4 | 15632 | 1249 |
Nfkb1,Nfkbia,Jun,Traf2 |
| 4.167e-02 | -3.18 | SA_TRKA_RECEPTOR | MSigDB lists | SA_TRKA_RECEPTOR | 17 | 4 | 15632 | 1249 |
Map2k1,Cdkn1a,Pik3cd,Akt3 |
| 4.167e-02 | -3.18 | BARRIER_COLON_CANCER_RECURRENCE_DN | MSigDB lists | BARRIER_COLON_CANCER_RECURRENCE_DN | 17 | 4 | 15632 | 1249 |
Pfkl,Stat2,Cited2,Asb13 |
| 4.167e-02 | -3.18 | chr6p23 | MSigDB lists | chr6p23 | 17 | 4 | 15632 | 1249 |
Eef1e1,Cd83,Edn1,Dek |
| 4.168e-02 | -3.18 | MODULE_375 | MSigDB lists | MODULE_375 | 77 | 11 | 15632 | 1249 |
Cx3cr1,Ccr1,Ednrb,Gna15,Fpr2,P2ry14,Fpr1,Ptafr,Adrb2,Cxcl1,Dgka |
| 4.168e-02 | -3.18 | GO_REGULATION_OF_CARBOHYDRATE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CARBOHYDRATE_BIOSYNTHETIC_PROCESS | 77 | 11 | 15632 | 1249 |
Nfkb1,Dyrk2,Ptger4,Plek,Ptafr,Irs2,Ptpn2,Kat2b,Il6,Gfpt1,Pdgfb |
| 4.168e-02 | -3.18 | BASSO_HAIRY_CELL_LEUKEMIA_UP | MSigDB lists | BASSO_HAIRY_CELL_LEUKEMIA_UP | 77 | 11 | 15632 | 1249 |
Timp1,Plod2,Il18,Spry2,Actb,Rtn2,Thbs1,Scn1b,Ccnd1,Rin2,Kctd12 |
| 4.173e-02 | -3.18 | IGF1R signaling cascade | REACTOME pathways | R-MMU-2428924 | 266 | 32 | 8608 | 757 |
Psmb10,Psmb8,Ptk2,Met,Psmd10,Trib3,Psma6,Psme2,Rapgef2,Psmb9,Rasgrp1,Dusp5,Psme1,Dusp6,Psmb6,Kitl,Spred1,Tlr9,Pdgfb,Psme2b,Angpt1,Src,Ppp2r5a,Irs2,Il2rg,Igf1r,Ksr1,Pdgfrb,Ppp2r1b,Pde3b,Map2k1,Jak2 |
| 4.173e-02 | -3.18 | IRS-related events triggered by IGF1R | REACTOME pathways | R-MMU-2428928 | 266 | 32 | 8608 | 757 |
Pdgfrb,Igf1r,Il2rg,Ksr1,Map2k1,Jak2,Ppp2r1b,Pde3b,Tlr9,Pdgfb,Kitl,Spred1,Ppp2r5a,Irs2,Src,Psme2b,Angpt1,Psmb9,Rasgrp1,Rapgef2,Dusp6,Psmb6,Dusp5,Psme1,Psmb8,Met,Ptk2,Psmb10,Trib3,Psma6,Psme2,Psmd10 |
| 4.174e-02 | -3.18 | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_DN | MSigDB lists | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_DN | 176 | 21 | 15632 | 1249 |
Pla2g7,Mmd,Pde1b,Ptch1,Clmp,Syk,Cx3cr1,Olfml3,Kitl,Lpcat2,Bmp2,Rgs1,Fam20c,Ciita,Pilra,Dmxl2,F11r,Itga9,Mmp9,Slc30a4,Tmem176b |
| 4.174e-02 | -3.18 | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP | MSigDB lists | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP | 176 | 21 | 15632 | 1249 |
Ccdc86,Egr2,Katna1,Pde7b,Leng9,Junb,Card6,Rnf31,Fos,Whamm,Hcls1,Atp2b4,Ncoa7,Relb,Samhd1,Egr3,Egr1,Slc39a13,Kdm4a,Irs2,Pik3cd |
| 4.174e-02 | -3.18 | GSE13306_TREG_VS_TCONV_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_UP | 176 | 21 | 15632 | 1249 |
Kat2b,Ccnd2,Nupr1,Csrnp1,Frmd6,Tfec,Kitl,Thbs1,Arf4,Timp1,Tagln,Dusp1,Nfkbia,Stx6,Tdrd7,Zscan29,Phlda1,Tlr1,Isg20,Ddit4,Csf1 |
| 4.174e-02 | -3.18 | GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_DN | MSigDB lists | GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_DN | 176 | 21 | 15632 | 1249 |
Ttc9c,Armcx6,Psmb9,Eno1,Tmem184b,Trip13,Mdm2,Hivep3,Ebi3,Dram1,Abr,Tpi1,Mcoln2,Usp42,Spata13,Ikbke,Nfkb2,Slc48a1,Relb,Zc3hav1,Tnfaip3 |
| 4.174e-02 | -3.18 | GSE13493_DP_VS_CD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_DP_VS_CD8POS_THYMOCYTE_UP | 176 | 21 | 15632 | 1249 |
Med13,Pde5a,Stx6,Trim56,Ifit2,Ttc9c,Ptch1,D16Ertd472e,Atp6v1d,Itgal,Hcls1,Col27a1,Snn,Ap3m2,Fmnl2,Csrnp1,Rhoh,Marcksl1,Slco3a1,Il4ra,Nkiras1 |
| 4.174e-02 | -3.18 | GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_UP | MSigDB lists | GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_UP | 176 | 21 | 15632 | 1249 |
Rsad2,Spint2,Arhgap26,Tbc1d1,Ccr3,Kcnj2,Ext1,Dock4,P2ry2,Gna15,Rgs14,Slc16a3,Clic5,Nfil3,Gfi1,Atp2b4,Mapkbp1,Socs1,Sdc1,Hlx,Ier2 |
| 4.174e-02 | -3.18 | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_DN | 176 | 21 | 15632 | 1249 |
Ets2,Srm,Snx10,Stx6,Ggct,Mcm6,Mthfd2,Trib3,Slc43a3,Cd200,Mcoln2,Egr3,Dusp14,Keap1,Prpf38a,Il15ra,Mitd1,Fbxo4,Clic4,Nfxl1,Osbpl3 |
| 4.174e-02 | -3.18 | GSE43863_NAIVE_VS_TFH_CD4_EFF_TCELL_D6_LCMV_UP | MSigDB lists | GSE43863_NAIVE_VS_TFH_CD4_EFF_TCELL_D6_LCMV_UP | 176 | 21 | 15632 | 1249 |
Ccnd2,Filip1l,Itga5,Egr1,Htr2b,Rhoc,Ifna2,Ifna1,Pbx1,Flrt2,Spic,Serp1,Dusp1,Dpy19l1,Ppp1r14b,Rnf19a,Ifna5,Srxn1,Ifna6,Prkce,Flnb |
| 4.178e-02 | -3.18 | drug transport | biological process | GO:0015893 | 147 | 16 | 20694 | 1406 |
Slc7a11,Inhba,Pdpn,Abcb1a,Slc25a25,Slc31a1,Edn1,Gja1,Slc25a22,Nfkbie,Abcc1,Slc25a12,Abcc4,Slc13a3,Slc7a2,Stra6l |
| 4.191e-02 | -3.17 | REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING | MSigDB lists | REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING | 41 | 7 | 15632 | 1249 |
Akt3,Mdm2,Phlpp1,Rictor,Cdkn1a,Nr4a1,Trib3 |
| 4.191e-02 | -3.17 | MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_UP | MSigDB lists | MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_UP | 41 | 7 | 15632 | 1249 |
Bmp2,Slc44a1,Ext1,Fgr,Nfkb1,Malt1,Fas |
| 4.191e-02 | -3.17 | CHENG_RESPONSE_TO_NICKEL_ACETATE | MSigDB lists | CHENG_RESPONSE_TO_NICKEL_ACETATE | 41 | 7 | 15632 | 1249 |
Cebpd,Jun,Rbbp8,Tlk2,Ms4a6d,Cp,Sla |
| 4.191e-02 | -3.17 | PID_CXCR3_PATHWAY | MSigDB lists | PID_CXCR3_PATHWAY | 41 | 7 | 15632 | 1249 |
Pf4,Rictor,Src,Map2k1,Cxcl10,Pik3cd,Itgal |
| 4.191e-02 | -3.17 | GO_REGULATION_OF_BONE_REMODELING | MSigDB lists | GO_REGULATION_OF_BONE_REMODELING | 41 | 7 | 15632 | 1249 |
Src,Ptger4,Gja1,Syk,Ubash3b,Cd38,Tnfaip3 |
| 4.191e-02 | -3.17 | GO_POSITIVE_REGULATION_OF_DEPHOSPHORYLATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_DEPHOSPHORYLATION | 41 | 7 | 15632 | 1249 |
Ripk3,Bmp2,Ppp2r5a,Jak2,Pdgfrb,Ppp1r15a,Plek |
| 4.191e-02 | -3.17 | GO_REGULATION_OF_PLASMA_LIPOPROTEIN_PARTICLE_LEVELS | MSigDB lists | GO_REGULATION_OF_PLASMA_LIPOPROTEIN_PARTICLE_LEVELS | 41 | 7 | 15632 | 1249 |
Hmox1,Ehd1,Msr1,Lipg,Ldlr,Plagl2,Pla2g7 |
| 4.191e-02 | -3.17 | ZHAN_MULTIPLE_MYELOMA_CD2_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD2_UP | 41 | 7 | 15632 | 1249 |
Dyrk2,Src,Ptprj,Sdc2,Phlpp2,Tnfsf8,Traf5 |
| 4.191e-02 | -3.17 | BROWNE_HCMV_INFECTION_8HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_8HR_DN | 41 | 7 | 15632 | 1249 |
Myc,Lrp8,Spn,Plau,Tpx2,Cebpd,Pim1 |
| 4.191e-02 | -3.17 | ZHAN_MULTIPLE_MYELOMA_HP_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_HP_DN | 41 | 7 | 15632 | 1249 |
Myo1b,Timp1,Cd86,St3gal1,Wars,Dek,Rbms1 |
| 4.203e-02 | -3.17 | hexose metabolic process | biological process | GO:0019318 | 124 | 14 | 20694 | 1406 |
Gpd2,Tnf,Hk1,Pgk1,Pcx,Pgm1,Hk2,Pfkl,Pdk3,Tpi1,Atf3,Serp1,Ldha,Myc |
| 4.215e-02 | -3.17 | smooth muscle cell differentiation | biological process | GO:0051145 | 48 | 7 | 20694 | 1406 |
Pdgfb,Sgcb,Mecp2,Notch1,Acvr1,Ednrb,Pdgfrb |
| 4.215e-02 | -3.17 | positive regulation of cell cycle G1/S phase transition | biological process | GO:1902808 | 48 | 7 | 20694 | 1406 |
Ccnd2,Mdm2,Ankrd17,Ube2e2,Rgcc,Ccnd1,Ccne1 |
| 4.217e-02 | -3.17 | MULLIGHAN_MLL_SIGNATURE_1_UP | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_1_UP | 346 | 37 | 15632 | 1249 |
C1rl,Irf8,Tor1aip1,Psd4,Psmb8,Ccr1,Dach1,Snx10,Tor3a,Tdrd7,Reps1,Adrb2,Ptafr,Mppe1,Rcan1,Slc43a3,Rnf19b,Hcls1,Il1rn,Rbbp8,Ptpn2,Tank,Cd302,Eno1,Arhgef3,Rgs14,Casp1,Syk,Slc16a3,Ikzf1,Nlrp3,Malt1,Abr,Sla,Batf,Pilra,Prdx1 |
| 4.229e-02 | -3.16 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_COMMON_LYMPHOID_PROGENITOR_UP | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_COMMON_LYMPHOID_PROGENITOR_UP | 166 | 20 | 15632 | 1249 |
Slc2a1,Eno1,Serpine1,Hopx,Dusp6,Casp1,Cebpd,Ift57,Ext1,Fut8,Slc9a1,Cdk5r1,Slco3a1,P2ry14,Tlr3,Glrx,Crim1,H3f3b,Lipg,Cxcl1 |
| 4.229e-02 | -3.16 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_DN | 166 | 20 | 15632 | 1249 |
Dhrs9,Rnf114,Cd302,Adap2,Fos,Dennd1b,Trim14,I830077J02Rik,Dock10,Fgl2,Oasl1,Slc31a1,Hhex,Rnf135,Ubash3b,Cd180,Pgm1,Lpcat2,Nfxl1,Samhd1 |
| 4.229e-02 | -3.16 | JNK_DN.V1_DN | MSigDB lists | JNK_DN.V1_DN | 166 | 20 | 15632 | 1249 |
Nfkbil1,Kpna3,Pml,Lrp8,Pim2,Rnd1,Cdc42ep2,Vegfc,Src,Bcl2l11,Rgs14,Irf8,Bcl9,Pdgfb,Nrp2,Dusp8,Mafk,Acvrl1,Vasp,Dusp4 |
| 4.229e-02 | -3.16 | GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP | 166 | 20 | 15632 | 1249 |
Mafg,Slc30a1,Nxf1,Usp42,Acvr1b,Mapkapk2,Rnf139,Pgs1,Nfil3,Snn,Cd83,Tmem184b,Arid5a,Tnfrsf1b,Pik3r5,Sqstm1,Ppp1r14b,Phlpp1,Kdm5b,Fchsd2 |
| 4.229e-02 | -3.16 | GSE15659_RESTING_VS_ACTIVATED_TREG_DN | MSigDB lists | GSE15659_RESTING_VS_ACTIVATED_TREG_DN | 166 | 20 | 15632 | 1249 |
Prkx,Rhoc,Tnfaip3,Vcpip1,Tpi1,Spata5l1,Slc43a3,Rab9,Ppp2r5a,Procr,Tbc1d1,Tyk2,Tdrd7,Rhou,Xaf1,S1pr2,Wars,Tnf,Tor1aip1,Ppm1k |
| 4.229e-02 | -3.16 | GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_UP | 166 | 20 | 15632 | 1249 |
Icosl,Srxn1,Slfn8,Tnfsf15,Ccnd1,Dpy19l1,P2ry12,Serp1,Batf,Slfn9,Ahsa1,Fam20c,Lpcat2,Tnfrsf14,Slc37a3,Myo10,Prpf38a,Aim2,Hlx,Malt1 |
| 4.240e-02 | -3.16 | positive regulation of hormone secretion | biological process | GO:0046887 | 159 | 17 | 20694 | 1406 |
Ptger4,Lif,Nlgn2,Hif1a,Edn1,Jak2,Gja1,Irs2,Cacna1d,Hcar2,Prkce,Clcf1,Cd38,Gpr68,Sirt1,Serp1,Glrx |
| 4.244e-02 | -3.16 | TEF1_Q6 | MSigDB lists | TEF1_Q6 | 197 | 23 | 15632 | 1249 |
Olfml3,Tnks1bp1,Pbx1,Etv3,Ccnd2,Slc39a13,Prrg4,Mapkapk2,Il18bp,Tor1aip2,Dennd1b,Egr2,Swap70,Ehd1,Plekhn1,Notch2,Dr1,Nfkb2,Ppp2r1b,Frmd4a,Ptprj,Ppa1,Cnn3 |
| 4.249e-02 | -3.16 | GO_MEMBRANE_LIPID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_MEMBRANE_LIPID_BIOSYNTHETIC_PROCESS | 106 | 14 | 15632 | 1249 |
Plaur,St3gal3,St3gal1,Ppm1l,St3gal6,Pigv,Sphk1,Sgms2,Mppe1,St3gal5,Gbgt1,B3gnt5,Cers6,Degs2 |
| 4.254e-02 | -3.16 | TNFR | smart domains | SM00208 | 23 | 5 | 9567 | 823 |
Tnfrsf8,Tnfrsf1b,Cd40,Fas,Tnfrsf14 |
| 4.257e-02 | -3.16 | CH | pfam domains | PF00307 | 65 | 9 | 18711 | 1348 |
Lrch1,Cnn2,Tagln,Syne2,Flnb,Dst,Cnn3,Lrch3,Micall2 |
| 4.261e-02 | -3.16 | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN | MSigDB lists | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN | 379 | 40 | 15632 | 1249 |
Sesn3,Rnf14,Klf2,Plk2,H2-Aa,Ddit4,Tmeff1,Cd69,Dcp1a,Il18rap,Rapgef2,Cd55,Naa25,Mthfd2,Pik3cd,Ddx4,Slamf8,Parp11,Gbp2b,Zcchc2,Acsl5,Vrk2,Sp110,Ppfibp2,Ets2,Dock4,Tnfsf8,Pdpn,Sat1,Rnf139,Cdkn2d,Ier2,Slco3a1,Phip,Ciapin1,Tspo,Prdx1,Prpf4,Tle3,Etv5 |
| 4.261e-02 | -3.16 | PDEase | interpro domains | IPR023088 | 19 | 4 | 19984 | 1430 |
Pde1b,Pde7b,Pde5a,Pde4b |
| 4.264e-02 | -3.15 | Melanoma | KEGG pathways | mmu05218 | 69 | 11 | 7931 | 713 |
Met,Map2k1,Pik3cd,Cdkn1a,Pdgfrb,Mdm2,Akt3,Pdgfb,Pdgfc,Igf1r,Ccnd1 |
| 4.264e-02 | -3.15 | Melanoma | KEGG pathways | ko05218 | 69 | 11 | 7931 | 713 |
Cdkn1a,Met,Pik3cd,Map2k1,Pdgfc,Pdgfb,Ccnd1,Igf1r,Pdgfrb,Akt3,Mdm2 |
| 4.269e-02 | -3.15 | HMGIY_Q6 | MSigDB lists | HMGIY_Q6 | 218 | 25 | 15632 | 1249 |
Rin2,Cd40,Bcl6,Nfkbia,Plagl2,Batf,Calcrl,Etv3,Cd180,Icam1,Lif,Prrg4,Il18rap,Ppp2r3a,Csf3,Ube2e2,Lmo4,Dusp6,Mier3,Stip1,Il1rn,Map3k8,Cxcl10,Ptgir,Tnfsf4 |
| 4.269e-02 | -3.15 | SPRY | smart domains | SM00449 | 72 | 11 | 9567 | 823 |
Rnf135,Trim21,Trim30d,Trim26,Trim34a,Trim12c,Spsb1,Spryd7,Mid1,Trim14,Trim30a |
| 4.270e-02 | -3.15 | Autodegradation of Cdh1 by Cdh1:APC/C | REACTOME pathways | R-MMU-174084 | 62 | 10 | 8608 | 757 |
Psma6,Psmb6,Psme2,Psme2b,Psmd10,Ube2e1,Psme1,Psmb8,Psmb9,Psmb10 |
| 4.275e-02 | -3.15 | NOTCH_DN.V1_UP | MSigDB lists | NOTCH_DN.V1_UP | 156 | 19 | 15632 | 1249 |
Hmox1,Pim2,Itpkc,Mefv,Stat2,Inpp1,Gng11,Cdkn1a,Gsta3,Ifit1bl2,Ifit1bl1,Abtb2,S100a8,Slc39a4,Tnfsf8,Btg2,Ksr1,Rasgrp1,Pla2g7 |
| 4.275e-02 | -3.15 | GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_UP | MSigDB lists | GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_UP | 156 | 19 | 15632 | 1249 |
Mgat1,Jun,Cd274,Lrp4,Ppp1r15b,Parp12,Sdc2,Rnf24,Phlda1,Cish,Ttc39b,Socs1,Hcar2,Nlgn2,Agpat4,Tnip1,Smg7,Pim3,Sdc4 |
| 4.279e-02 | -3.15 | DANG_REGULATED_BY_MYC_UP | MSigDB lists | DANG_REGULATED_BY_MYC_UP | 68 | 10 | 15632 | 1249 |
Slc16a1,Slc7a5,Txn1,Txnrd1,Srm,Uchl1,Traf2,Homer1,Serpine1,Slc2a1 |
| 4.279e-02 | -3.15 | chr4q21 | MSigDB lists | chr4q21 | 68 | 10 | 15632 | 1249 |
Ccng2,Cxcl2,Aff1,G3bp2,Cxcl1,Stat3,Herc3,Cxcl10,Ankrd17,Plac8 |
| 4.282e-02 | -3.15 | dendrite terminus | cellular component | GO:0044292 | 20 | 4 | 20747 | 1409 |
Ptch1,Grk3,Cyfip1,Ift57 |
| 4.283e-02 | -3.15 | Polyamine biosynthesis, arginine => ornithine => putrescine | KEGG pathways | mmu_M00134 | 4 | 2 | 7931 | 713 |
Arg2,Odc1 |
| 4.283e-02 | -3.15 | Polyamine biosynthesis, arginine => ornithine => putrescine | KEGG pathways | M00134 | 4 | 2 | 7931 | 713 |
Odc1,Arg2 |
| 4.288e-02 | -3.15 | tetrahydrofolate metabolic process | biological process | GO:0046653 | 20 | 4 | 20694 | 1406 |
Mthfd2,Mthfr,Gch1,Mthfd1l |
| 4.288e-02 | -3.15 | regulation of membrane invagination | biological process | GO:1905153 | 20 | 4 | 20694 | 1406 |
C3,Siglece,Fcgr1,Stap1 |
| 4.288e-02 | -3.15 | sialylation | biological process | GO:0097503 | 20 | 4 | 20694 | 1406 |
St3gal6,St3gal1,St3gal3,St3gal5 |
| 4.288e-02 | -3.15 | regulation of leukocyte adhesion to vascular endothelial cell | biological process | GO:1904994 | 20 | 4 | 20694 | 1406 |
Itga4,Tnf,Icam1,Ptafr |
| 4.288e-02 | -3.15 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological process | GO:1900151 | 20 | 4 | 20694 | 1406 |
Zfp36,Polr2g,Tent4a,Btg2 |
| 4.288e-02 | -3.15 | positive regulation of amyloid precursor protein catabolic process | biological process | GO:1902993 | 20 | 4 | 20694 | 1406 |
Tnf,Casp3,Lyn,Gsap |
| 4.288e-02 | -3.15 | calcium-mediated signaling using intracellular calcium source | biological process | GO:0035584 | 20 | 4 | 20694 | 1406 |
Kdr,Prnp,Ptprj,Vcam1 |
| 4.288e-02 | -3.15 | response to amine | biological process | GO:0014075 | 20 | 4 | 20694 | 1406 |
Htr2b,Adora2a,Pde1b,Hdac1 |
| 4.288e-02 | -3.15 | positive regulation of translational initiation | biological process | GO:0045948 | 20 | 4 | 20694 | 1406 |
Tnf,Ythdf1,Nck1,Polr2g |
| 4.288e-02 | -3.15 | response to mitochondrial depolarisation | biological process | GO:0098780 | 20 | 4 | 20694 | 1406 |
Mul1,Optn,Sqstm1,Hk2 |
| 4.288e-02 | -3.15 | leukocyte migration involved in inflammatory response | biological process | GO:0002523 | 20 | 4 | 20694 | 1406 |
Ccl2,Cx3cl1,S100a8,Slamf8 |
| 4.288e-02 | -3.15 | mitochondrial fission | biological process | GO:0000266 | 20 | 4 | 20694 | 1406 |
Mtfr2,Mx1,Mx2,Mul1 |
| 4.302e-02 | -3.15 | GTGCAAA_MIR507 | MSigDB lists | GTGCAAA_MIR507 | 116 | 15 | 15632 | 1249 |
Nr4a3,Dgkh,Mtdh,Prdm1,Cpeb4,Chd9,Rsbn1,Osm,Ptpn2,Eif4g2,Slc4a7,Fam43a,Mdm2,Prkce,Rab21 |
| 4.305e-02 | -3.15 | Metabolism of vitamins and cofactors | REACTOME pathways | R-MMU-196854 | 161 | 21 | 8608 | 757 |
Pcx,Mthfd1l,Acp5,Sdc1,Mthfd2,Bst1,Sdc2,Cd38,Gpc1,Parp10,Parp9,Sdc4,Ldlr,Slc2a1,Lrp8,Agrn,Pdzd11,Mthfr,Mocs1,Nampt,Ptgs2 |
| 4.308e-02 | -3.14 | GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN | MSigDB lists | GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN | 146 | 18 | 15632 | 1249 |
Herc3,Rnd3,Stard7,Slfn5,Snn,Pim2,Gpd2,Pigv,Adrb2,Rab20,Ikzf1,Cdyl2,Rapgef2,Acvrl1,Ifit1bl1,Ifit1bl2,Daam1,Rrs1 |
| 4.308e-02 | -3.14 | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_UP | MSigDB lists | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_UP | 146 | 18 | 15632 | 1249 |
Setdb2,Samd9l,Rapgef2,Treml2,Tor3a,Hivep2,Heatr6,Snapc1,Dr1,Zhx2,Atp11b,Stard7,Ppa1,Hhex,Slc30a4,Azi2,Fpr1,Nkiras1 |
| 4.308e-02 | -3.14 | ASTON_MAJOR_DEPRESSIVE_DISORDER_DN | MSigDB lists | ASTON_MAJOR_DEPRESSIVE_DISORDER_DN | 146 | 18 | 15632 | 1249 |
Bbx,Eef1e1,Ppp2r3a,Hspa2,Brd2,Lipe,Atm,Slc31a2,Lmo4,Cnp,Sema3c,Cldnd1,Plagl2,Ppfibp2,Stip1,Lrp8,Rnf19b,Lpar1 |
| 4.308e-02 | -3.14 | DARWICHE_PAPILLOMA_RISK_LOW_DN | MSigDB lists | DARWICHE_PAPILLOMA_RISK_LOW_DN | 146 | 18 | 15632 | 1249 |
Cited2,Otud1,Swap70,Itpr1,Asns,Bcl2a1b,Plac8,Cx3cr1,Bcl2a1d,Rnf19a,Cp,Icam1,Slc39a13,Denr,Samhd1,Cdc42ep2,Bcl2a1a,Fbrsl1 |
| 4.317e-02 | -3.14 | GO_CYTOPLASMIC_VESICLE_PART | MSigDB lists | GO_CYTOPLASMIC_VESICLE_PART | 568 | 57 | 15632 | 1249 |
Fcgr1,Dmxl2,Tlr6,Scarf1,Ap3b1,Aftph,Irgm2,Msr1,H2-Q4,Rab32,Ap3m2,Ldlr,Znrf1,Tmem67,Whamm,Rab20,Tlr2,Sema4c,Ptch1,Cav1,Marco,Lnpep,Agtrap,Cd74,H2-Q7,Mdm2,Rhoq,Dbnl,Rab11fip1,Rab9,Rab21,Timp1,Itpr1,H2-Q6,Hsph1,Pf4,Sec24b,Abcc4,Vegfc,Il15ra,Clic4,Sec24a,Thbs1,Pcdh7,Spire1,Hp,H2-Ab1,H2-Aa,Tlr1,Rab10,Pdgfb,Inpp5b,Vps54,Serpine1,Fzd5,Gja1,H2-Eb1 |
| 4.319e-02 | -3.14 | camera-type eye morphogenesis | biological process | GO:0048593 | 136 | 15 | 20694 | 1406 |
Fzd5,Slc4a7,Ikzf1,Zeb1,Cited2,Tdrd7,Phactr4,Tsku,Flt1,Kdr,Casz1,Hif1a,Zhx2,Notch2,Jag1 |
| 4.322e-02 | -3.14 | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_DN | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_DN | 187 | 22 | 15632 | 1249 |
Rab21,Dnaja1,Fos,Tle3,Slfn5,Chmp4b,Adar,Sla,Nlrp3,Coa5,Icam1,Tmem176a,Pik3r6,Slc7a2,Ogfr,Rel,Tuba4a,Myadm,Slc7a8,Tnfaip2,Fam102b,Dnaja2 |
| 4.322e-02 | -3.14 | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | 187 | 22 | 15632 | 1249 |
F10,Usp18,Sdc1,Aldh1b1,Palld,Ncoa5,Vcan,Parp9,Msr1,Cenpe,Trim36,Flt1,Plod3,Nfil3,Cdc42ep4,Tapbpl,Tbc1d13,Etv6,Fam72a,Rasgrp1,Piezo1,Irf7 |
| 4.322e-02 | -3.14 | GO_REGULATION_OF_ION_HOMEOSTASIS | MSigDB lists | GO_REGULATION_OF_ION_HOMEOSTASIS | 187 | 22 | 15632 | 1249 |
Ubash3b,Cxcl10,Lyn,Slc30a1,Ptger4,Slc30a4,Pml,Htr2b,Gclc,Htr2a,Tspo,Kdr,Itpr1,Cav1,Src,Ednrb,Gja1,Hap1,Edn1,Gclm,Prkce,Scn1b |
| 4.322e-02 | -3.14 | myeloid cell development | biological process | GO:0061515 | 69 | 9 | 20694 | 1406 |
Tlr2,Tmod3,Jmjd6,Src,Arid4a,Bcl6,Fam20c,Klf2,Cited2 |
| 4.322e-02 | -3.14 | sulfur compound biosynthetic process | biological process | GO:0044272 | 69 | 9 | 20694 | 1406 |
Gclc,Papss2,Acsl5,Chst11,Acsl1,Angpt1,Mthfr,Dse,Gclm |
| 4.325e-02 | -3.14 | GO_DIVALENT_INORGANIC_CATION_HOMEOSTASIS | MSigDB lists | GO_DIVALENT_INORGANIC_CATION_HOMEOSTASIS | 325 | 35 | 15632 | 1249 |
Cd55,Grina,Cacnb3,Lpar1,Jak2,Il1b,Htr2b,Xcr1,Ednrb,Ccl5,Gja1,S100a8,Ccr1,P2ry2,Gna15,Cav1,Slc39a14,Pml,Slc30a4,Slc30a1,Tmtc2,Slc39a13,Htr2a,Atp2b4,Cd38,Ccl12,Cd40,Itpr1,Swap70,Prkce,Slc39a4,Ccl2,Ccr3,Edn1,Atp13a1 |
| 4.326e-02 | -3.14 | GO_TUBE_FORMATION | MSigDB lists | GO_TUBE_FORMATION | 126 | 16 | 15632 | 1249 |
Notch1,Lhx2,Apaf1,Sec24b,Sdc4,Hif1a,Tulp3,Sema4c,Phactr4,Ift57,Vasp,Fzd1,Ptch1,Lmo4,Mthfd1l,Bcl2l11 |
| 4.326e-02 | -3.14 | AACWWCAANK_UNKNOWN | MSigDB lists | AACWWCAANK_UNKNOWN | 126 | 16 | 15632 | 1249 |
Dock4,Jarid2,Dach1,Ppp2r3a,Ccdc25,Mllt6,Top3a,Bbx,Max,Abr,Egr3,Prdm1,Vcpip1,Nfil3,Stau1,Sh3bgrl2 |
| 4.326e-02 | -3.14 | GO_COPPER_ION_BINDING | MSigDB lists | GO_COPPER_ION_BINDING | 50 | 8 | 15632 | 1249 |
Cox17,Gpc1,Cp,Cutc,Prnp,Sco1,Il1a,Lox |
| 4.326e-02 | -3.14 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | MSigDB lists | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | 50 | 8 | 15632 | 1249 |
Cdkn1a,Angpt1,Ptk2,Nck1,Stat5a,Tnf,Nfkb1,Itga5 |
| 4.326e-02 | -3.14 | WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER | MSigDB lists | WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER | 50 | 8 | 15632 | 1249 |
Fgl2,Vcan,Rgs1,Nr4a3,Cx3cr1,H2-Ab1,Plek,Nr4a1 |
| 4.326e-02 | -3.14 | JOHNSTONE_PARVB_TARGETS_1_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_1_DN | 50 | 8 | 15632 | 1249 |
Myo10,Itgb8,Rbms1,Tnc,Dse,Lnpep,Slc25a37,Ptger4 |
| 4.326e-02 | -3.14 | TTCNRGNNNNTTC_HSF_Q6 | MSigDB lists | TTCNRGNNNNTTC_HSF_Q6 | 136 | 17 | 15632 | 1249 |
Stip1,Ahsa1,Jmjd6,Nr4a3,Phf6,Lrp8,Rtn1,Egr3,Stk40,Cept1,Zfp800,Edn1,Dnaja1,Fosb,Hspa1a,C1rl,Hsph1 |
| 4.326e-02 | -3.14 | YTAAYNGCT_UNKNOWN | MSigDB lists | YTAAYNGCT_UNKNOWN | 136 | 17 | 15632 | 1249 |
Lmo4,Flrt3,Sesn3,Tshz1,Ampd3,Egr2,Ccnd2,Atf3,Hhex,Tpi1,Epsti1,Dio2,H3f3b,Rhoc,Plagl2,Tnfsf10,Pbx1 |
| 4.330e-02 | -3.14 | Leptin Insulin Overlap | WikiPathways | WP578 | 18 | 5 | 4813 | 540 |
Stat3,Socs1,Irs2,Jak2,Socs3 |
| 4.330e-02 | -3.14 | Small Ligand GPCRs | WikiPathways | WP353 | 18 | 5 | 4813 | 540 |
Ptafr,Ptgir,S1pr2,Lpar1,Ptger4 |
| 4.331e-02 | -3.14 | MHC class I protein complex | cellular component | GO:0042612 | 12 | 3 | 20747 | 1409 |
H2-Q6,H2-Q7,H2-Q4 |
| 4.331e-02 | -3.14 | MCM complex | cellular component | GO:0042555 | 12 | 3 | 20747 | 1409 |
Mcmbp,Mcm6,Mcm9 |
| 4.335e-02 | -3.14 | positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization | biological process | GO:1904925 | 12 | 3 | 20694 | 1406 |
Mul1,Optn,Hk2 |
| 4.335e-02 | -3.14 | cellular response to increased oxygen levels | biological process | GO:0036295 | 12 | 3 | 20694 | 1406 |
Fas,Nox1,Cav1 |
| 4.335e-02 | -3.14 | removal of superoxide radicals | biological process | GO:0019430 | 12 | 3 | 20694 | 1406 |
Sod2,Prdx1,Nqo1 |
| 4.335e-02 | -3.14 | regulation of male gonad development | biological process | GO:2000018 | 12 | 3 | 20694 | 1406 |
Il1a,Cited2,Abcb1a |
| 4.335e-02 | -3.14 | activation of MAPKKK activity | biological process | GO:0000185 | 12 | 3 | 20694 | 1406 |
Gadd45g,Tnf,Gadd45b |
| 4.335e-02 | -3.14 | positive regulation of anion transmembrane transport | biological process | GO:1903961 | 12 | 3 | 20694 | 1406 |
Abcb1a,Acsl5,Ptafr |
| 4.335e-02 | -3.14 | CD8-positive, alpha-beta T cell activation | biological process | GO:0036037 | 12 | 3 | 20694 | 1406 |
Irf1,Tnfsf8,Gpr18 |
| 4.335e-02 | -3.14 | regulation of nitric oxide mediated signal transduction | biological process | GO:0010749 | 12 | 3 | 20694 | 1406 |
Pde5a,Thbs1,Atp2b4 |
| 4.335e-02 | -3.14 | cellular response to zinc ion | biological process | GO:0071294 | 12 | 3 | 20694 | 1406 |
Hvcn1,Mt1,Mt2 |
| 4.335e-02 | -3.14 | regulation of adipose tissue development | biological process | GO:1904177 | 12 | 3 | 20694 | 1406 |
Sirt1,Plaat3,Klf7 |
| 4.335e-02 | -3.14 | negative regulation of interleukin-6 secretion | biological process | GO:1900165 | 12 | 3 | 20694 | 1406 |
Zc3h12a,Cd200,Rabgef1 |
| 4.335e-02 | -3.14 | positive regulation of interferon-gamma biosynthetic process | biological process | GO:0045078 | 12 | 3 | 20694 | 1406 |
Il27,Tlr9,Tlr3 |
| 4.335e-02 | -3.14 | negative regulation of hormone biosynthetic process | biological process | GO:0032353 | 12 | 3 | 20694 | 1406 |
Nfkb1,Gfi1,Bmp2 |
| 4.335e-02 | -3.14 | tonic smooth muscle contraction | biological process | GO:0014820 | 12 | 3 | 20694 | 1406 |
Edn1,Htr2a,Cd38 |
| 4.335e-02 | -3.14 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | biological process | GO:0060213 | 12 | 3 | 20694 | 1406 |
Btg2,Polr2g,Zfp36 |
| 4.335e-02 | -3.14 | plasminogen activation | biological process | GO:0031639 | 12 | 3 | 20694 | 1406 |
Plau,Pgk1,Plat |
| 4.335e-02 | -3.14 | negative regulation of lymphocyte migration | biological process | GO:2000402 | 12 | 3 | 20694 | 1406 |
Ccl12,Cd200,Lrch1 |
| 4.335e-02 | -3.14 | regulation of glomerular mesangial cell proliferation | biological process | GO:0072124 | 12 | 3 | 20694 | 1406 |
Cflar,Pdgfb,Egr1 |
| 4.335e-02 | -3.14 | regulation of cell-cell adhesion mediated by integrin | biological process | GO:0033632 | 12 | 3 | 20694 | 1406 |
Piezo1,Swap70,Ccl5 |
| 4.335e-02 | -3.14 | regulation of histone H3-K9 trimethylation | biological process | GO:1900112 | 12 | 3 | 20694 | 1406 |
Sirt1,Mecp2,Kdm4a |
| 4.335e-02 | -3.14 | fibroblast migration | biological process | GO:0010761 | 12 | 3 | 20694 | 1406 |
Arid5b,Pml,Syne2 |
| 4.336e-02 | -3.14 | NFE2_01 | MSigDB lists | NFE2_01 | 250 | 28 | 15632 | 1249 |
Prdm1,Clcn5,Spred1,Angpt1,Eno1,Dync1h1,Src,N4bp1,Sqstm1,Ass1,Cst7,Mdm2,Rbpms,Gadd45g,Bnip3,Il6,Pde1b,Slc31a1,Dtx2,Cdkn1a,Hcls1,Il10,Snx10,Slc7a8,Tuba4a,Maff,Vasp,Akt3 |
| 4.340e-02 | -3.14 | Gluconeogenesis | REACTOME pathways | R-MMU-70263 | 30 | 6 | 8608 | 757 |
Tpi1,Eno2,Pgk1,Eno1,Slc25a12,Pcx |
| 4.340e-02 | -3.14 | Non-integrin membrane-ECM interactions | REACTOME pathways | R-MMU-3000171 | 30 | 6 | 8608 | 757 |
Sdc1,Pdgfb,Tnc,Sdc4,Sdc2,Itgav |
| 4.340e-02 | -3.14 | GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION | 59 | 9 | 15632 | 1249 |
Myc,Kitl,Vegfc,Notch1,Cx3cr1,Stat1,Hif1a,Irs2,Cx3cl1 |
| 4.340e-02 | -3.14 | CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 | MSigDB lists | CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 | 59 | 9 | 15632 | 1249 |
Slc2a1,Casp8,Fgr,Socs1,Cd200,Tnfrsf1b,Itga5,Dgka,Vcan |
| 4.347e-02 | -3.14 | GO_PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY | MSigDB lists | GO_PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY | 87 | 12 | 15632 | 1249 |
Plcl2,Pde3b,Pde1b,Smpdl3b,Pde5a,Pde7b,Ccr1,Pde4b,Ccl5,Hmox1,Mppe1,Cnp |
| 4.347e-02 | -3.14 | MODULE_97 | MSigDB lists | MODULE_97 | 87 | 12 | 15632 | 1249 |
Slc25a22,Crkl,Scyl2,Smc5,Usp25,Tagap,Cd164,Zhx2,G3bp2,Mdm2,Bnip3,Peli1 |
| 4.347e-02 | -3.14 | DE_YY1_TARGETS_DN | MSigDB lists | DE_YY1_TARGETS_DN | 87 | 12 | 15632 | 1249 |
Rbl1,Ift57,Met,Angpt1,Inhba,Clic4,Rbbp8,Hif1a,Lpar1,Itgav,Itga4,Fas |
| 4.347e-02 | -3.14 | GO_PDZ_DOMAIN_BINDING | MSigDB lists | GO_PDZ_DOMAIN_BINDING | 87 | 12 | 15632 | 1249 |
Gng12,Atp2b4,Crim1,F11r,Lpar1,Apba1,Rapgef2,Sdc2,Fzd1,Dock4,Plekha2,Gja1 |
| 4.352e-02 | -3.13 | PP2C | pfam domains | PF00481 | 19 | 4 | 18711 | 1348 |
Phlpp2,Ppm1k,Phlpp1,Ppm1l |
| 4.360e-02 | -3.13 | Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | REACTOME pathways | R-MMU-2404192 | 267 | 32 | 8608 | 757 |
Psmb10,Psmb8,Ptk2,Met,Psmd10,Trib3,Psma6,Psme2,Rapgef2,Psmb9,Rasgrp1,Dusp5,Psme1,Dusp6,Psmb6,Kitl,Spred1,Tlr9,Pdgfb,Psme2b,Angpt1,Ppp2r5a,Irs2,Src,Igf1r,Il2rg,Ksr1,Pdgfrb,Pde3b,Ppp2r1b,Map2k1,Jak2 |
| 4.366e-02 | -3.13 | histone demethylation | biological process | GO:0016577 | 29 | 5 | 20694 | 1406 |
Jmjd6,Kdm4a,Jarid2,Kdm5b,Kdm6b |
| 4.366e-02 | -3.13 | protein sumoylation | biological process | GO:0016925 | 29 | 5 | 20694 | 1406 |
Ifih1,Mul1,Mdm2,Egr2,Ranbp2 |
| 4.366e-02 | -3.13 | regulation of smooth muscle cell apoptotic process | biological process | GO:0034391 | 29 | 5 | 20694 | 1406 |
Map2k4,Sirt1,Il12b,Edn1,Sod2 |
| 4.366e-02 | -3.13 | cellular response to gamma radiation | biological process | GO:0071480 | 29 | 5 | 20694 | 1406 |
Mdm2,Cdkn1a,Atm,Tlk2,Egr1 |
| 4.366e-02 | -3.13 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902235 | 29 | 5 | 20694 | 1406 |
Grina,Nck1,Ikbkg,Sirt1,Ptpn2 |
| 4.366e-02 | -3.13 | unsaturated fatty acid biosynthetic process | biological process | GO:0006636 | 29 | 5 | 20694 | 1406 |
Ptgs2,Edn1,Sphk1,Cd74,Ptges |
| 4.389e-02 | -3.13 | dendrite | cellular component | GO:0030425 | 694 | 59 | 20747 | 1409 |
Igsf9,Ccl2,Lrp8,Sipa1l1,Stau1,Cdk5r1,Map2k4,Adrb2,Lpar1,Ctla2a,Psd,Nqo1,Htr2a,Cnn3,Kif3c,Pdgfb,Grk3,Nr3c1,Map2k1,Fcgr2b,Bnip3,Cyfip1,Ptch1,Kif5c,Homer1,Fscn1,Glrx,Apba1,Lrp4,Cpeb4,Rgs14,Stat1,Prkar2b,Plk2,Hdc,Dbnl,Adora2a,Ift57,Cacna1d,Hap1,Ptk2,Htr2b,Mark2,Rab3ip,Plk3,Pde4b,Arf4,Xrn1,Prnp,Txn1,Kcnj2,Ero1l,Acvrl1,Nlgn2,Max,Dock10,Fas,Met,Itpr1 |
| 4.394e-02 | -3.12 | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY8_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY8_EFFECTOR_CD8_TCELL_UP | 177 | 21 | 15632 | 1249 |
Btg2,Slc44a1,Rhoq,Hivep3,Stat4,Arid4a,4930523C07Rik,Rabgef1,Dusp6,Ptch1,Ccl4,Tax1bp1,Cd38,Etv5,Ahr,Prdm1,Cd200,Slc31a1,Pml,Sdc1,Trib1 |
| 4.394e-02 | -3.12 | KEGG_ENDOCYTOSIS | MSigDB lists | KEGG_ENDOCYTOSIS | 177 | 21 | 15632 | 1249 |
Kdr,Ldlr,Chmp4b,Igf1r,Asap3,H2-Q7,Il2rg,Adrb2,Pikfyve,Rab11fip1,Met,Hspa2,Mdm2,Psd,Psd4,Ehd1,H2-Q4,Src,Flt1,Hspa1a,H2-Q6 |
| 4.394e-02 | -3.12 | GSE7852_TREG_VS_TCONV_THYMUS_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_THYMUS_DN | 177 | 21 | 15632 | 1249 |
Dyrk2,Egr1,Acvr1b,Adrb2,Znrf3,Slco3a1,Hinfp,Herc3,Slc29a3,Rap2c,Daxx,Dusp6,Otud1,Acpp,Gpr18,Inpp5b,Zfp36,Slc39a14,Kremen1,Vcan,Cdyl2 |
| 4.394e-02 | -3.12 | GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_UP | MSigDB lists | GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_UP | 177 | 21 | 15632 | 1249 |
Stat1,Smc5,Frmd4a,Socs1,Grina,Ak4,Slc28a2,Agpat4,Il15ra,Rab3ip,Myadm,Fam43a,Cx3cr1,Zyx,Bcl6,Col11a2,Arid5a,Fcgr2b,Leng9,Tbc1d13,Tyk2 |
| 4.394e-02 | -3.12 | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP | 177 | 21 | 15632 | 1249 |
Srm,Ezr,Tmem184b,Eno1,Noc4l,Slc7a5,Fut8,Ift57,Cox17,Tpi1,Lif,Magohb,Mcm10,Traf1,Ciapin1,Ccnd2,Slc43a3,Odc1,Tap1,Ppp2r2a,Wdr43 |
| 4.394e-02 | -3.12 | GSE17721_4_VS_24H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_4_VS_24H_GARDIQUIMOD_BMDC_DN | 177 | 21 | 15632 | 1249 |
Lmo4,Cav1,Srm,Txn1,Pcx,Psma6,C1ra,Car13,Rhoq,Slc15a3,Tulp3,Parp3,Rars,Htr2b,Stard7,Esd,Tspo,Hcls1,Rbms2,Acsl5,Pfkfb3 |
| 4.394e-02 | -3.12 | GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_UP | 177 | 21 | 15632 | 1249 |
Dgka,Ccrl2,Itgb8,Piezo1,Lrch1,Casp4,Cd302,Cenpe,Mvp,Tnfaip3,Trafd1,Dcbld2,Gca,Rgs1,Pcdh7,Socs1,Papss2,Pim1,Traf3ip2,Pim2,St3gal1 |
| 4.403e-02 | -3.12 | regulation of bone mineralization | biological process | GO:0030500 | 80 | 10 | 20694 | 1406 |
Adrb2,Fam20c,Hif1a,Gja1,Bcor,Ccr1,Isg15,Srgn,Bmp2,Acvr1 |
| 4.404e-02 | -3.12 | GRADE_COLON_AND_RECTAL_CANCER_UP | MSigDB lists | GRADE_COLON_AND_RECTAL_CANCER_UP | 261 | 29 | 15632 | 1249 |
Pnpt1,Gclc,Prdx1,Traf5,Plau,Lrp8,Tpi1,Spata13,Myc,Carhsp1,Sod2,Dpy19l1,Gpsm2,Ets2,Timp1,Ldha,Ppa1,Kpna3,Mthfd2,Tgfbi,Rcn1,Ampd3,Timeless,Nmi,Ddit4,Eef1e1,Gdf15,Pdk3,Ubr4 |
| 4.414e-02 | -3.12 | Inflammatory Response Pathway | WikiPathways | WP458 | 30 | 7 | 4813 | 540 |
Cd86,Cd80,Cd40,Il2rg,Tnfrsf1b,Il4ra,Thbs1 |
| 4.416e-02 | -3.12 | collagen binding | molecular function | GO:0005518 | 68 | 9 | 20217 | 1400 |
Tgfbi,Mmp13,Srgn,Hsd17b12,Pdgfb,Gpc1,Thbs1,Itga9,Antxr1 |
| 4.418e-02 | -3.12 | GO_PROTEIN_K63_LINKED_UBIQUITINATION | MSigDB lists | GO_PROTEIN_K63_LINKED_UBIQUITINATION | 33 | 6 | 15632 | 1249 |
Traf2,Trim56,Ube2e2,Trim12c,Bfar,Ube2f |
| 4.418e-02 | -3.12 | GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_METABOLIC_PROCESS | 33 | 6 | 15632 | 1249 |
Prdx5,Pdgfrb,Errfi1,Ccl12,Il6,Ciita |
| 4.418e-02 | -3.12 | FIGUEROA_AML_METHYLATION_CLUSTER_3_DN | MSigDB lists | FIGUEROA_AML_METHYLATION_CLUSTER_3_DN | 33 | 6 | 15632 | 1249 |
Tlr1,Batf2,Plekha4,Ppp1r15a,Plek,Phldb1 |
| 4.418e-02 | -3.12 | chr16q12 | MSigDB lists | chr16q12 | 33 | 6 | 15632 | 1249 |
N4bp1,Nod2,Nqo1,Rpgrip1l,Chd9,Lpcat2 |
| 4.418e-02 | -3.12 | GO_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | MSigDB lists | GO_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | 33 | 6 | 15632 | 1249 |
Ptch1,Stat1,Notch1,Jag1,Cd34,Pdgfb |
| 4.418e-02 | -3.12 | YAGI_AML_RELAPSE_PROGNOSIS | MSigDB lists | YAGI_AML_RELAPSE_PROGNOSIS | 33 | 6 | 15632 | 1249 |
Tspo,Cd14,Nfkbia,Rab32,Zyx,Bst1 |
| 4.418e-02 | -3.12 | GO_RESPONSE_TO_MONOAMINE | MSigDB lists | GO_RESPONSE_TO_MONOAMINE | 33 | 6 | 15632 | 1249 |
Pde4b,Adrb2,Nr4a3,Slc9a1,Htr2b,Atp2b4 |
| 4.418e-02 | -3.12 | GO_CAMP_METABOLIC_PROCESS | MSigDB lists | GO_CAMP_METABOLIC_PROCESS | 33 | 6 | 15632 | 1249 |
Calcrl,Adora2a,Pde7b,Pde4b,Pde3b,Pde1b |
| 4.418e-02 | -3.12 | GO_REGULATION_OF_CELL_AGING | MSigDB lists | GO_REGULATION_OF_CELL_AGING | 33 | 6 | 15632 | 1249 |
Pnpt1,Nek6,Bcl6,Eef1e1,Hmga1,Sirt1 |
| 4.418e-02 | -3.12 | YIH_RESPONSE_TO_ARSENITE_C3 | MSigDB lists | YIH_RESPONSE_TO_ARSENITE_C3 | 33 | 6 | 15632 | 1249 |
Mdm2,Pim1,Glrx,Mxd1,Itgav,Nek6 |
| 4.418e-02 | -3.12 | PID_IL8_CXCR2_PATHWAY | MSigDB lists | PID_IL8_CXCR2_PATHWAY | 33 | 6 | 15632 | 1249 |
Hck,Vasp,Gna15,Lyn,Pik3r6,Fgr |
| 4.418e-02 | -3.12 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 33 | 6 | 15632 | 1249 |
Grina,Ppp1r15a,Ppp1r15b,Usp25,Bfar,Nck1 |
| 4.418e-02 | -3.12 | GO_REGULATION_OF_BONE_RESORPTION | MSigDB lists | GO_REGULATION_OF_BONE_RESORPTION | 33 | 6 | 15632 | 1249 |
Ptger4,Src,Syk,Cd38,Ubash3b,Tnfaip3 |
| 4.421e-02 | -3.12 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0090092 | 232 | 23 | 20694 | 1406 |
Notch1,Zeb1,Lgals9,Sirt1,Gdf15,Vasn,Pmepa1,Chst11,Inhba,Cav1,Notch2,Bmp2,Acvr1,Acvrl1,Thbs1,Lox,Fzd1,Acvr1b,Htra1,Rbpms,Kdr,Bambi,Cited2 |
| 4.422e-02 | -3.12 | SCF-beta-TrCP mediated degradation of Emi1 | REACTOME pathways | R-MMU-174113 | 54 | 9 | 8608 | 757 |
Psmd10,Psme1,Psme2b,Psmb6,Psme2,Psma6,Psmb10,Psmb9,Psmb8 |
| 4.422e-02 | -3.12 | Degradation of AXIN | REACTOME pathways | R-MMU-4641257 | 54 | 9 | 8608 | 757 |
Psmd10,Psme1,Psme2b,Psmb6,Psme2,Psma6,Psmb10,Psmb9,Psmb8 |
| 4.422e-02 | -3.12 | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | REACTOME pathways | R-MMU-8854050 | 54 | 9 | 8608 | 757 |
Psmb8,Psmb9,Psmb10,Psmb6,Psme2,Psma6,Psmd10,Psme1,Psme2b |
| 4.424e-02 | -3.12 | Tscrpt_reg_Myc_N | interpro domains | IPR012682 | 5 | 2 | 19984 | 1430 |
Myc,Mycl |
| 4.424e-02 | -3.12 | CLIC | interpro domains | IPR002946 | 5 | 2 | 19984 | 1430 |
Clic5,Clic4 |
| 4.424e-02 | -3.12 | ClpA/B | interpro domains | IPR001270 | 5 | 2 | 19984 | 1430 |
Tor3a,Trip13 |
| 4.424e-02 | -3.12 | Adenosn_rcpt | interpro domains | IPR001634 | 5 | 2 | 19984 | 1430 |
Adora2a,Adora2b |
| 4.424e-02 | -3.12 | Pyr_nucl-diS_OxRdtase_dimer | interpro domains | IPR004099 | 5 | 2 | 19984 | 1430 |
Txnrd1,Gsr |
| 4.424e-02 | -3.12 | GT64 | interpro domains | IPR015338 | 5 | 2 | 19984 | 1430 |
Ext1,Extl2 |
| 4.424e-02 | -3.12 | Pyr_nuc-diS_OxRdtase | interpro domains | IPR001100 | 5 | 2 | 19984 | 1430 |
Txnrd1,Gsr |
| 4.424e-02 | -3.12 | Deltex_C_sf | interpro domains | IPR039399 | 5 | 2 | 19984 | 1430 |
Dtx2,Dtx3l |
| 4.424e-02 | -3.12 | HSP_DnaJ_Cys-rich_dom | interpro domains | IPR001305 | 5 | 2 | 19984 | 1430 |
Dnaja2,Dnaja1 |
| 4.424e-02 | -3.12 | LRAT_dom | interpro domains | IPR007053 | 5 | 2 | 19984 | 1430 |
Lratd2,Plaat3 |
| 4.424e-02 | -3.12 | Notch-like_dom_sf | interpro domains | IPR035993 | 5 | 2 | 19984 | 1430 |
Notch2,Notch1 |
| 4.424e-02 | -3.12 | Znf_C5HC2 | interpro domains | IPR004198 | 5 | 2 | 19984 | 1430 |
Kdm5b,Jarid2 |
| 4.424e-02 | -3.12 | Nucleoside_phosphorylase_d | interpro domains | IPR000845 | 5 | 2 | 19984 | 1430 |
Upp1,Pnp2 |
| 4.424e-02 | -3.12 | GATase_2_dom | interpro domains | IPR017932 | 5 | 2 | 19984 | 1430 |
Gfpt1,Asns |
| 4.424e-02 | -3.12 | Nucleoside_phosphorylase_sf | interpro domains | IPR035994 | 5 | 2 | 19984 | 1430 |
Upp1,Pnp2 |
| 4.424e-02 | -3.12 | Tscrpt_reg_Myc | interpro domains | IPR002418 | 5 | 2 | 19984 | 1430 |
Mycl,Myc |
| 4.424e-02 | -3.12 | Deltex_C | interpro domains | IPR039396 | 5 | 2 | 19984 | 1430 |
Dtx2,Dtx3l |
| 4.424e-02 | -3.12 | Exostosin | interpro domains | IPR004263 | 5 | 2 | 19984 | 1430 |
Ext1,Extl2 |
| 4.424e-02 | -3.12 | Deltex_fam | interpro domains | IPR039398 | 5 | 2 | 19984 | 1430 |
Dtx2,Dtx3l |
| 4.424e-02 | -3.12 | Pyr_OxRdtase_I_AS | interpro domains | IPR012999 | 5 | 2 | 19984 | 1430 |
Txnrd1,Gsr |
| 4.424e-02 | -3.12 | Znf_Sec23_Sec24_sf | interpro domains | IPR036174 | 5 | 2 | 19984 | 1430 |
Sec24b,Sec24a |
| 4.424e-02 | -3.12 | Cdc42_effect | interpro domains | IPR029273 | 5 | 2 | 19984 | 1430 |
Cdc42ep4,Cdc42ep2 |
| 4.424e-02 | -3.12 | POLO_box_dom | interpro domains | IPR000959 | 5 | 2 | 19984 | 1430 |
Plk3,Plk2 |
| 4.438e-02 | -3.11 | cell projection membrane | cellular component | GO:0031253 | 294 | 28 | 20747 | 1409 |
Psd4,Mosmo,Pdpn,Spata13,Ptprj,Fscn1,Ehd1,Syne2,Plek,Phlpp2,Slc7a11,Antxr1,Phlpp1,Ddx58,Arf4,Abcb1a,Ezr,Src,P2ry12,Fgr,Itga5,Scimp,Psd,Nox1,Cacna1d,Tmem67,Adora2a,Itgav |
| 4.450e-02 | -3.11 | nephron development | biological process | GO:0072006 | 125 | 14 | 20694 | 1406 |
Notch2,Ahr,Pbx1,Egr1,Jag1,Pdgfb,Cited2,Ptch1,Bmp2,Notch1,Myc,Timeless,Pdgfrb,Angpt1 |
| 4.457e-02 | -3.11 | cyclic-nucleotide-mediated signaling | biological process | GO:0019935 | 160 | 17 | 20694 | 1406 |
Ptger4,Prkar2b,Adgre4,Htr2b,Cxcl10,Ksr1,Calcrl,Adora2a,Ahr,Pf4,Adrb2,Rapgef2,Ednrb,Adgrg6,Adgrl2,Adora2b,Ptgir |
| 4.457e-02 | -3.11 | regulation of calcium ion transmembrane transport | biological process | GO:1903169 | 160 | 17 | 20694 | 1406 |
Hap1,Gem,Tlr9,Adrb2,Cacnb3,Pde4b,Slc9a1,Prnp,Gpr35,Lyn,Cacna1d,Prkce,Cx3cl1,Ahr,Ubash3b,Hspa2,Cxcl10 |
| 4.459e-02 | -3.11 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_DN | 167 | 20 | 15632 | 1249 |
Egr1,Smc5,Ier2,Slc30a1,Cd180,Asf1a,Ccl4,Siglece,Arf4,Clcn7,Apaf1,Tuba4a,Klf6,Tnf,Cenpe,Ubr4,Myc,Btg2,Atp13a1,Gsr |
| 4.466e-02 | -3.11 | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | REACTOME pathways | R-MMU-174178 | 71 | 11 | 8608 | 757 |
Psmb10,Psmb8,Ube2e1,Psmd10,Psme2b,Pttg1,Psme2,Psma6,Psmb9,Psme1,Psmb6 |
| 4.468e-02 | -3.11 | GO_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | 97 | 13 | 15632 | 1249 |
Triobp,Vegfc,Kdr,Prkce,Jak2,Csf1,Sdc4,Plekha2,Itga5,Myadm,Rac3,Ptprj,Hsd17b12 |
| 4.468e-02 | -3.11 | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | MSigDB lists | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | 97 | 13 | 15632 | 1249 |
Spry2,Akt3,Prkce,Pde1b,Rictor,Mdm2,Phlpp1,Cdkn1a,Prkar2b,Nr4a1,Src,Trib3,Map2k1 |
| 4.472e-02 | -3.11 | ubiquitin-like protein ligase activity | molecular function | GO:0061659 | 240 | 24 | 20217 | 1400 |
Znrf3,Cop1,Rabgef1,Fbxo4,Rnf14,Arel1,Ankib1,Med21,Rnf19b,Rffl,Rnf24,Rnf139,Birc3,Trim56,Bfar,Rnf145,Rnf19a,Egr2,Rnf34,Herc6,Peli1,Birc2,Mdm2,Znrf1 |
| 4.478e-02 | -3.11 | mouse chr18 | chromosome location | mouse chr18 | 153 | 15 | 24173 | 1464 |
Gm4841,Pdgfrb,Nr3c1,Rnf14,Cd74,Map3k8,Egr1,Lox,Tshz1,Gypc,Pstpip2,Zeb1,Cd14,Adrb2,Trim36 |
| 4.480e-02 | -3.11 | POLO_box | pfam domains | PF00659 | 5 | 2 | 18711 | 1348 |
Plk2,Plk3 |
| 4.480e-02 | -3.11 | zf-C5HC2 | pfam domains | PF02928 | 5 | 2 | 18711 | 1348 |
Kdm5b,Jarid2 |
| 4.480e-02 | -3.11 | PNP_UDP_1 | pfam domains | PF01048 | 5 | 2 | 18711 | 1348 |
Pnp2,Upp1 |
| 4.480e-02 | -3.11 | DTC | pfam domains | PF18102 | 5 | 2 | 18711 | 1348 |
Dtx3l,Dtx2 |
| 4.480e-02 | -3.11 | Pyr_redox_dim | pfam domains | PF02852 | 5 | 2 | 18711 | 1348 |
Gsr,Txnrd1 |
| 4.480e-02 | -3.11 | LRAT | pfam domains | PF04970 | 5 | 2 | 18711 | 1348 |
Lratd2,Plaat3 |
| 4.480e-02 | -3.11 | Glyco_transf_64 | pfam domains | PF09258 | 5 | 2 | 18711 | 1348 |
Ext1,Extl2 |
| 4.480e-02 | -3.11 | Myc_N | pfam domains | PF01056 | 5 | 2 | 18711 | 1348 |
Myc,Mycl |
| 4.480e-02 | -3.11 | BORG_CEP | pfam domains | PF14957 | 5 | 2 | 18711 | 1348 |
Cdc42ep4,Cdc42ep2 |
| 4.480e-02 | -3.11 | GO_RESPONSE_TO_COPPER_ION | MSigDB lists | GO_RESPONSE_TO_COPPER_ION | 25 | 5 | 15632 | 1249 |
Il1a,Icam1,Prnp,Cp,Nfkb1 |
| 4.480e-02 | -3.11 | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 25 | 5 | 15632 | 1249 |
Sirt1,Grina,Ptpn2,Nck1,Bcl2l11 |
| 4.480e-02 | -3.11 | LIANG_SILENCED_BY_METHYLATION_UP | MSigDB lists | LIANG_SILENCED_BY_METHYLATION_UP | 25 | 5 | 15632 | 1249 |
Tnfsf4,C3,Stat1,Ccnd2,Olr1 |
| 4.480e-02 | -3.11 | GO_CELL_DIFFERENTIATION_INVOLVED_IN_EMBRYONIC_PLACENTA_DEVELOPMENT | MSigDB lists | GO_CELL_DIFFERENTIATION_INVOLVED_IN_EMBRYONIC_PLACENTA_DEVELOPMENT | 25 | 5 | 15632 | 1249 |
Prdm1,Socs3,Lif,Fzd5,Casp8 |
| 4.480e-02 | -3.11 | GO_NEGATIVE_REGULATION_OF_CELL_KILLING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_KILLING | 25 | 5 | 15632 | 1249 |
H2-Q6,Tap1,Serpinb9,H2-Q7,H2-Q4 |
| 4.480e-02 | -3.11 | GO_NADP_METABOLIC_PROCESS | MSigDB lists | GO_NADP_METABOLIC_PROCESS | 25 | 5 | 15632 | 1249 |
Nox1,Tpi1,Pgm1,Prdx5,Me1 |
| 4.480e-02 | -3.11 | WATANABE_COLON_CANCER_MSI_VS_MSS_UP | MSigDB lists | WATANABE_COLON_CANCER_MSI_VS_MSS_UP | 25 | 5 | 15632 | 1249 |
Etv5,Casp2,Dusp4,Pla2g4a,Rgs1 |
| 4.480e-02 | -3.11 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | MSigDB lists | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | 25 | 5 | 15632 | 1249 |
Cacnb3,Gng12,Gnb4,Gng11,Gng4 |
| 4.480e-02 | -3.11 | BIOCARTA_PYK2_PATHWAY | MSigDB lists | BIOCARTA_PYK2_PATHWAY | 25 | 5 | 15632 | 1249 |
Map2k1,Jun,Map2k4,Src,Crkl |
| 4.480e-02 | -3.11 | MODULE_226 | MSigDB lists | MODULE_226 | 25 | 5 | 15632 | 1249 |
Dusp5,Dusp6,Serpinb2,Arf4,Dusp14 |
| 4.480e-02 | -3.11 | GO_T_CELL_MEDIATED_IMMUNITY | MSigDB lists | GO_T_CELL_MEDIATED_IMMUNITY | 25 | 5 | 15632 | 1249 |
Icam1,Jag1,Ctsc,Cd55,Dennd1b |
| 4.480e-02 | -3.11 | GENTILE_UV_HIGH_DOSE_UP | MSigDB lists | GENTILE_UV_HIGH_DOSE_UP | 25 | 5 | 15632 | 1249 |
Nupr1,Sat1,Atf3,Isg15,Maff |
| 4.480e-02 | -3.11 | GO_REGULATION_OF_NATURAL_KILLER_CELL_ACTIVATION | MSigDB lists | GO_REGULATION_OF_NATURAL_KILLER_CELL_ACTIVATION | 25 | 5 | 15632 | 1249 |
Il18,Il12b,Rasgrp1,Axl,Il15 |
| 4.480e-02 | -3.11 | GO_ZINC_II_ION_TRANSPORT | MSigDB lists | GO_ZINC_II_ION_TRANSPORT | 25 | 5 | 15632 | 1249 |
Slc39a4,Slc30a4,Slc30a1,Slc39a13,Slc39a14 |
| 4.480e-02 | -3.11 | GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS | 25 | 5 | 15632 | 1249 |
Ccl5,Bcl6,Irs2,Cd74,Hif1a |
| 4.480e-02 | -3.11 | CHIN_BREAST_CANCER_COPY_NUMBER_UP | MSigDB lists | CHIN_BREAST_CANCER_COPY_NUMBER_UP | 25 | 5 | 15632 | 1249 |
Myc,Ext1,Ptk2,Ptgs2,Ccnd1 |
| 4.483e-02 | -3.10 | protein phosphatase 2A binding | molecular function | GO:0051721 | 38 | 6 | 20217 | 1400 |
Ppp2r2a,Cpd,Adrb2,Smg7,Stat1,Sphk1 |
| 4.483e-02 | -3.10 | translation initiation factor binding | molecular function | GO:0031369 | 38 | 6 | 20217 | 1400 |
Myc,Nck1,Hhex,Polr2g,Larp1,Gch1 |
| 4.514e-02 | -3.10 | GSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_UP | MSigDB lists | GSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_UP | 157 | 19 | 15632 | 1249 |
Notch1,Lacc1,Pdgfc,Thbs1,Gng11,Dnajb4,Dtwd1,Dgkh,Atf3,Csrnp1,Hdac1,Dusp4,Maff,Hk2,Rnf24,Myo1b,Tiparp,Slc25a37,Ahrr |
| 4.514e-02 | -3.10 | GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_UP | 157 | 19 | 15632 | 1249 |
Icosl,Phlpp1,Tnfrsf1b,Pik3r5,Sqstm1,Map4k4,Ppp6r1,Arid5a,Serpine1,Sik3,Actb,Whamm,Smg7,Tle3,Smox,Pml,Mapkapk2,Fam133b,Nxf1 |
| 4.515e-02 | -3.10 | lipid biosynthetic process | biological process | GO:0008610 | 421 | 38 | 20694 | 1406 |
Sgms2,Pbx1,Plpp1,Ptges,Hmgcs1,Edn1,Sphk1,Dhrs9,Pdss1,Nr1h3,Ch25h,Lpcat2,Cd74,Mppe1,Acsl5,Cers6,Lipg,Hsd17b12,Ptgs2,Tspo,Pgap2,Acsl1,Plaat3,Agpat4,Atm,Dgka,Idi1,Asah2,St3gal6,Cept1,Plscr1,Pigv,Pgs1,Hsd17b7,Etnk1,Degs2,Pik3cd,B3gnt5 |
| 4.517e-02 | -3.10 | cytoplasmic microtubule organization | biological process | GO:0031122 | 59 | 8 | 20694 | 1406 |
Plk3,Katna1,Ccdc88b,Ezr,Fignl2,Dync1h1,Cenpj,Dst |
| 4.517e-02 | -3.10 | labyrinthine layer development | biological process | GO:0060711 | 59 | 8 | 20694 | 1406 |
Itga4,Fzd5,Vcam1,Spint2,Socs3,Junb,Il10,Map2k1 |
| 4.517e-02 | -3.10 | JUBAN_TARGETS_OF_SPI1_AND_FLI1_DN | MSigDB lists | JUBAN_TARGETS_OF_SPI1_AND_FLI1_DN | 78 | 11 | 15632 | 1249 |
Rcl1,Fam162a,Foxp4,Tpi1,Ptgir,Ldha,Myc,Pdss1,S1pr2,Tnfrsf1b,Ppp1r14b |
| 4.529e-02 | -3.09 | folate transformations I | BIOCYC pathways | MOUSE_PWY-2201 | 9 | 3 | 1025 | 97 |
Mthfr,Mthfd1l,Mthfd2 |
| 4.531e-02 | -3.09 | protein catabolic process | biological process | GO:0030163 | 616 | 53 | 20694 | 1406 |
Arel1,Mdm2,Rnf139,Sirt1,Spsb1,Trim13,Isg15,Chmp4b,Usp18,Znrf1,Crbn,Tnfaip3,Keap1,Ube2l6,Fbxo4,Peli1,Ubr4,Ctsc,Ldlr,Atm,Usp25,Traf2,Usp12,Ankib1,Rnf14,Psma6,Gpc1,Psmb6,Dtx3l,Bnip3,Psmb10,Lnpep,Cop1,Rnf19b,Cnot4,Tmem67,Birc2,Dnajb2,Uchl1,Rnf19a,Arrdc4,Psmb9,Bfar,Klhl25,Pml,Casp8,Psmb8,Armc8,Uba7,Usp42,Rnf34,Znrf3,Rffl |
| 4.532e-02 | -3.09 | cellular response to environmental stimulus | biological process | GO:0104004 | 282 | 27 | 20694 | 1406 |
Gja1,Nox1,Casp3,Egr1,Hvcn1,Cav1,Relb,Actb,Sirt1,Mdm2,Lrrc8c,Ccnd2,Atm,Ptger4,Ptgs2,Cnn2,Piezo1,Rcsd1,Sde2,Tank,Fbxo4,Gpr68,Slc9a1,N4bp1,Tnks1bp1,Tlk2,Cdkn1a |
| 4.532e-02 | -3.09 | cellular response to abiotic stimulus | biological process | GO:0071214 | 282 | 27 | 20694 | 1406 |
Actb,Sirt1,Mdm2,Lrrc8c,Casp3,Gja1,Nox1,Egr1,Cav1,Hvcn1,Relb,Fbxo4,Sde2,Tank,Slc9a1,Gpr68,Tnks1bp1,N4bp1,Tlk2,Cdkn1a,Ccnd2,Atm,Ptger4,Cnn2,Ptgs2,Piezo1,Rcsd1 |
| 4.532e-02 | -3.09 | renal system development | biological process | GO:0072001 | 282 | 27 | 20694 | 1406 |
Odc1,Bmp2,Timeless,Angpt1,Bcl2l11,Lrp4,Jag1,Cited2,Pdgfb,Arg2,Vcan,Tet2,Notch1,Prkx,Arid5b,Rpgrip1l,Tiparp,Myc,Pdgfrb,Jmjd6,Notch2,Pbx1,Egr1,Ahr,Ptch1,Gsta3,Stat1 |
| 4.541e-02 | -3.09 | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | 188 | 22 | 15632 | 1249 |
Cd38,Clcn5,Cd180,Evl,Ube2e1,Slc30a4,Mllt6,Tlk2,B3gnt5,Slc44a1,Hivep2,Casp1,Pik3r5,Tmem229b,Kif3c,Il13ra1,Uchl1,Akt3,Junb,Eif4g2,Myadm,Nfkb1 |
| 4.541e-02 | -3.09 | GO_REGULATION_OF_MITOCHONDRION_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_MITOCHONDRION_ORGANIZATION | 188 | 22 | 15632 | 1249 |
Tnfsf10,Kdr,Stard7,Fam162a,Plaur,Mmp9,Adrb2,Rhou,Rnf31,Casp8,Pid1,Fzd5,Tspo,Plagl2,Mul1,Hif1a,Micall2,Bnip3,Ddhd1,Bcl2l11,Sqstm1,Psmd10 |
| 4.541e-02 | -3.09 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_DN | 188 | 22 | 15632 | 1249 |
Cyth3,Traf1,Marcksl1,Gda,Atp11b,Pfkfb3,Rnd3,Birc2,Slc16a3,Ogfrl1,Gsr,Clec5a,Kcna3,Rab20,C3,Igf1r,Cdkn1a,Gsta3,Kitl,Gja1,Mmd,Bst1 |
| 4.541e-02 | -3.09 | TCF11MAFG_01 | MSigDB lists | TCF11MAFG_01 | 188 | 22 | 15632 | 1249 |
Il13ra1,Uchl1,Tfec,Nlgn2,Angpt1,Spred1,Prdx1,Ptch1,Eno1,Lmo4,Ubr4,Cst7,Brd2,Txnrd1,Jarid2,Cd69,Ifnb1,Psma6,Mdm2,Il6,Pdgfb,Rab10 |
| 4.541e-02 | -3.09 | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_DN | MSigDB lists | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_DN | 188 | 22 | 15632 | 1249 |
Pfkl,Pfkfb3,Cd83,Il1rn,Rgs1,Hif1a,Cdk5r1,Arid5b,Dram1,C3,Snx2,Psd,Egln3,Tor1aip2,Tnfsf8,Phlda1,Rel,Lcp2,Ttc39c,Dock4,Fam43a,Mthfd1l |
| 4.541e-02 | -3.09 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_DN | 188 | 22 | 15632 | 1249 |
Srm,Sod2,Eif2ak2,Tnf,Irf4,Gclm,Tpi1,Jmjd6,Irf8,Trip13,Hk2,Cd200,Dck,Ppa1,Ptger4,Mthfd2,Serpinb9,Ccl4,Clic4,Idi1,Wdr43,Fam162a |
| 4.541e-02 | -3.09 | GSE339_CD4POS_VS_CD4CD8DN_DC_DN | MSigDB lists | GSE339_CD4POS_VS_CD4CD8DN_DC_DN | 188 | 22 | 15632 | 1249 |
Fosb,Tspan3,Casp1,Ppp1r14b,Ppp1r15b,Snx10,Kctd12,Ifrd1,Gbp4,Gbp9,Ccdc86,Mafg,Fam111a,Sema4a,Odc1,Slc31a1,Nek6,Frmd6,Ppp2r2a,Ldlr,Idi1,Prdx1 |
| 4.541e-02 | -3.09 | GSE15930_STIM_VS_STIM_AND_IL12_24H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL12_24H_CD8_T_CELL_DN | 188 | 22 | 15632 | 1249 |
Myo10,Inpp1,Pcdh7,Ifit3b,Isg15,Ier3,Irs2,Slc30a1,Il1a,Rtn1,Dnaja2,Rars,Ifnb1,Uba7,Nqo1,Hdac1,Pstpip2,Pdgfrb,Fosb,Ifit3,Gja1,Itgav |
| 4.549e-02 | -3.09 | G protein-coupled glutamate receptor binding | molecular function | GO:0035256 | 12 | 3 | 20217 | 1400 |
Adora2a,Homer1,Prnp |
| 4.549e-02 | -3.09 | peptidyl-proline dioxygenase activity | molecular function | GO:0031543 | 12 | 3 | 20217 | 1400 |
Egln3,P4ha1,P4ha2 |
| 4.549e-02 | -3.09 | activin binding | molecular function | GO:0048185 | 12 | 3 | 20217 | 1400 |
Acvr1,Acvr1b,Acvrl1 |
| 4.550e-02 | -3.09 | sialyltransferase activity | molecular function | GO:0008373 | 20 | 4 | 20217 | 1400 |
St3gal6,St3gal5,St3gal3,St3gal1 |
| 4.550e-02 | -3.09 | SUMO transferase activity | molecular function | GO:0019789 | 20 | 4 | 20217 | 1400 |
Ranbp2,Egr2,Mul1,Mdm2 |
| 4.558e-02 | -3.09 | anatomical structure maturation | biological process | GO:0071695 | 137 | 15 | 20694 | 1406 |
C3,Cx3cr1,Bmp2,Scarf1,Rnd1,Fam20c,Tut7,Cdk5r1,Pdgfb,Trip13,Klf2,Ankrd17,Mecp2,Hif1a,Gja1 |
| 4.558e-02 | -3.09 | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | 147 | 18 | 15632 | 1249 |
Fam111a,Mthfd2,Mcm6,Mcm10,Abr,H2-Ab1,Ldha,Rbl1,Cdkn1a,Eno1,Cenpe,Psat1,Eif2ak2,Ccne1,Snx2,Casp3,Mmp14,Trip13 |
| 4.558e-02 | -3.09 | GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_DN | 147 | 18 | 15632 | 1249 |
Stat3,Itgb8,Cx3cr1,Gja1,Cst7,Ifit3,Ptch1,Hdc,Pdgfrb,Cmklr1,Siglece,Nfil3,Atp10a,Palld,F11r,Sertad3,Adrb2,Ifit3b |
| 4.559e-02 | -3.09 | transmembrane receptor protein kinase activity | molecular function | GO:0019199 | 79 | 10 | 20217 | 1400 |
Igf1r,Axl,Acvr1b,Acvr1,Acvrl1,Pdgfrb,Met,Flt1,Kdr,Nrp2 |
| 4.559e-02 | -3.09 | protein kinase activator activity | molecular function | GO:0030295 | 79 | 10 | 20217 | 1400 |
Ccl5,Lgals9,Spry2,Mtcp1,Cdkn1a,Irgm2,Map2k1,Cdk5r1,Rgcc,Daxx |
| 4.563e-02 | -3.09 | ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN | 230 | 26 | 15632 | 1249 |
Arid4a,Tshz1,Tlr1,Smpdl3b,Ms4a6d,Frmd4a,Slc29a3,Chd9,Ldlr,Crbn,Dhrs9,Arhgef3,Nlrc4,Cited2,Irf4,Spry2,Setdb2,Kremen1,Rin2,Pde5a,Hhex,Tlr6,St3gal3,Sdc1,Dtwd1,Tle3 |
| 4.570e-02 | -3.09 | positive regulation of neuron differentiation | biological process | GO:0045666 | 460 | 41 | 20694 | 1406 |
Nr3c1,Rapgef2,Nck1,Met,Rab21,Hap1,Map2k1,Bmp2,Eif4g2,Etv5,Lif,Kdm4a,Scn1b,Il6,Mecp2,Cyfip1,Kif3c,Fzd1,Ehd1,Cflar,Mul1,Lpar1,Tcf4,Mmd,P2ry2,Cx3cl1,Bcl6,Sirt1,Mark2,Scarf1,Zeb1,Igf1r,Dbnl,D16Ertd472e,Sphk1,Nlgn2,Itpr1,Kat2b,Lyn,Ccl5,Lrp8 |
| 4.572e-02 | -3.09 | HP1SITEFACTOR_Q6 | MSigDB lists | HP1SITEFACTOR_Q6 | 209 | 24 | 15632 | 1249 |
Axl,Tet2,Bcl6,Cited2,Rhoq,Rin2,Tapbp,Hhex,Calcrl,Rgs3,Rab3ip,Tnks1bp1,Eif4g2,Map4k4,Lmo4,Casp8,Csf3,Jag1,Hivep3,Tnip3,Ppp2r1b,Gcnt2,H3f3b,Dio2 |
| 4.572e-02 | -3.09 | KONDO_EZH2_TARGETS | MSigDB lists | KONDO_EZH2_TARGETS | 209 | 24 | 15632 | 1249 |
Bcl2a1d,Cp,Arhgef3,Dock4,Ifit2,Fam43a,Klf3,Bcl2a1b,Cd164,St3gal6,Zeb1,Klf2,Ifit3,Serpine1,Gja1,Map4k4,Il1b,Bcl2a1a,Ust,Map3k8,Ifit3b,St3gal1,Shisa3,Il13ra1 |
| 4.572e-02 | -3.09 | GO_CELL_CORTEX | MSigDB lists | GO_CELL_CORTEX | 209 | 24 | 15632 | 1249 |
Wdr43,Tnfaip2,Spire1,Ptk2,Rab10,Flnb,Cav1,Nos2,Clic5,Myadm,Daxx,Myo10,Agtrap,Sele,Rai14,Dbnl,Traf2,Cd302,Slc2a1,Trip10,Gpsm2,Ezr,Phldb1,Gypc |
| 4.587e-02 | -3.08 | GSE6259_33D1_POS_DC_VS_BCELL_DN | MSigDB lists | GSE6259_33D1_POS_DC_VS_BCELL_DN | 137 | 17 | 15632 | 1249 |
Fgr,Mmp25,P2ry14,Gpr141,Palld,Tnfsf4,Ppp2r1b,Idi1,Osbpl3,Irf8,Cst7,Dock10,Vasp,Aebp2,Trip13,Timeless,Ly75 |
| 4.594e-02 | -3.08 | kinesin binding | molecular function | GO:0019894 | 48 | 7 | 20217 | 1400 |
Nek6,Dcp1a,Ktn1,Lrp8,Kif3c,Daxx,Actb |
| 4.596e-02 | -3.08 | PD-1 signaling | REACTOME pathways | R-MMU-389948 | 16 | 4 | 8608 | 757 |
H2-Eb1,H2-Aa,H2-Ab1,Cd274 |
| 4.596e-02 | -3.08 | Negative regulators of RIG-I/MDA5 signaling | REACTOME pathways | R-MMU-936440 | 16 | 4 | 8608 | 757 |
Tnfaip3,Tax1bp1,Ddx58,Ikbke |
| 4.604e-02 | -3.08 | lipid transport | biological process | GO:0006869 | 270 | 26 | 20694 | 1406 |
Abcc1,Xkr8,Pla2g4a,Ldlr,Stoml1,Plscr1,Stra6l,Stard5,Stard7,Nos2,Atp11b,Tspo,Acsl1,Osbpl3,Atp10a,Abcb1a,Acsl5,Gramd1a,Fabp3,Abcc4,Lipg,Inhba,Atp11a,Cav1,Msr1,Slco3a1 |
| 4.604e-02 | -3.08 | extracellular structure organization | biological process | GO:0043062 | 270 | 26 | 20694 | 1406 |
Nox1,Spint2,Col18a1,Pla2g7,Flrt2,Plagl2,Mmp9,P4ha1,Hsd17b12,Col27a1,Plod3,Lipg,Mmp25,Ptk2,Plod2,Mmp14,Mmp13,Ero1l,Col11a2,Nfkb2,Tnf,Lox,Kif9,Col4a2,Cd34,Tgfbi |
| 4.610e-02 | -3.08 | Synthesis and interconversion of nucleotide di- and triphosphates | REACTOME pathways | R-MMU-499943 | 23 | 5 | 8608 | 757 |
Ak4,Gsr,Txnrd1,Txn1,Glrx |
| 4.610e-02 | -3.08 | Metal ion SLC transporters | REACTOME pathways | R-MMU-425410 | 23 | 5 | 8608 | 757 |
Slc31a1,Cp,Slc30a1,Slc39a4,Slc39a14 |
| 4.612e-02 | -3.08 | Ube2n (ubiquitin-conjugating enzyme E2N) | protein interactions | 93765 | 21 | 5 | 7778 | 753 |
Ikbkg,Cd40,Tnfaip3,Tax1bp1,Traf2 |
| 4.612e-02 | -3.08 | FLOT1 (flotillin 1) | protein interactions | 10211 | 21 | 5 | 7778 | 753 |
Actb,Rmdn3,Tmod3,Chmp4b,Flnb |
| 4.612e-02 | -3.08 | FLOT2 (flotillin 2) | protein interactions | 2319 | 21 | 5 | 7778 | 753 |
Actb,Chmp4b,Flnb,Tmod3,Rmdn3 |
| 4.612e-02 | -3.08 | SPECC1 (sperm antigen with calponin homology and coiled-coil domains 1) | protein interactions | 92521 | 21 | 5 | 7778 | 753 |
Itga5,Actb,Tpm4,Tmod3,Flnb |
| 4.612e-02 | -3.08 | Cdkn1b (cyclin-dependent kinase inhibitor 1B) | protein interactions | 12576 | 21 | 5 | 7778 | 753 |
Ccnd2,Myc,Ccnd1,Jak2,Ccne1 |
| 4.615e-02 | -3.08 | GO_PLASMA_MEMBRANE_PROTEIN_COMPLEX | MSigDB lists | GO_PLASMA_MEMBRANE_PROTEIN_COMPLEX | 492 | 50 | 15632 | 1249 |
Cd74,Itga4,H2-Q7,Traf5,Bmp2,Traf2,H2-Q6,Cd40,Birc2,Lrp4,Acvr1,Hspa2,Casp3,Itgb8,Kcna3,H2-Ab1,Gng4,Gng12,Vcam1,Pde4b,H2-Eb1,Gja1,Il12rb1,H2-Aa,Tlr1,Scn1b,Mpp7,Fas,Tlr6,Sgcb,Gng11,H2-Q4,Itgav,Syk,Kcnj2,Il6,Acvr1b,Cacnb3,Itga9,Lyn,Tlr2,Nox1,Itga5,Il13ra1,Cacna1d,Cflar,Gna15,Itgal,Casp8,Rnf31 |
| 4.616e-02 | -3.08 | RASGEF_cat_dom | interpro domains | IPR001895 | 28 | 5 | 19984 | 1430 |
Rapgef2,Rapgef5,Rgl1,Rasgrp1,Ralgds |
| 4.616e-02 | -3.08 | Znf_C3HC4_RING-type | interpro domains | IPR018957 | 28 | 5 | 19984 | 1430 |
Traf2,Traf5,Trim30d,Trim21,Dtx2 |
| 4.619e-02 | -3.08 | intrinsic component of endoplasmic reticulum membrane | cellular component | GO:0031227 | 149 | 16 | 20747 | 1409 |
Ero1l,Dnajb2,Tapbp,H2-Q4,Lnpk,Gramd1a,Tap1,Dhrs9,Sgms2,Rrbp1,H2-Q6,Ext1,H2-Q7,Tap2,Itpr1,Slc37a3 |
| 4.622e-02 | -3.07 | activating transcription factor binding | molecular function | GO:0033613 | 90 | 11 | 20217 | 1400 |
Ciita,Hdac1,Crkl,Nek6,Psip1,Egr2,Myc,Cited2,Jun,Fos,Rbl1 |
| 4.623e-02 | -3.07 | GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | 178 | 21 | 15632 | 1249 |
Trim14,Ppp2r5a,Bbx,Stat4,Rasgrp1,Tdrd7,Triobp,Parp8,Sqstm1,Klf2,Cep350,Irf7,Cited2,Pilrb2,Rsbn1,Pilrb1,Traf5,Chd9,Zc3hav1,Armc8,Kcna3 |
| 4.623e-02 | -3.07 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN | 178 | 21 | 15632 | 1249 |
Nlrc5,Cd86,Bcl6,Plekha2,Peli1,Phlpp1,Uba7,Ptprj,Irf2,Marcksl1,Irf1,Ddx58,Ppm1l,Il4ra,Lyn,Nr4a3,Crlf3,Chd9,Slc29a3,Pmepa1,Zfp319 |
| 4.623e-02 | -3.07 | GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_UP | MSigDB lists | GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_UP | 178 | 21 | 15632 | 1249 |
Phldb1,Ets2,Mdn1,Tlr1,Noc4l,4932438A13Rik,Oas2,Ddx60,Ptk2,Ccnd2,Zfp281,Trim13,Calcrl,Nr4a3,Sell,Asb13,Crlf3,Sh3bgrl2,Aff1,Rab3ip,Stau1 |
| 4.623e-02 | -3.07 | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP | 178 | 21 | 15632 | 1249 |
Ccng2,Rictor,Acvr1,Rapgef2,Alas1,Ppp2r5a,Inpp5b,Casp1,Syk,Ifnar1,Bcl2l11,Tuba4a,Jarid2,Cdyl,Rbl1,Tle3,Extl2,Rcsd1,Aida,Tlr6,Fas |
| 4.623e-02 | -3.07 | GSE41978_WT_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41978_WT_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | 178 | 21 | 15632 | 1249 |
Fos,Klf3,Flt1,Ift57,Hk2,Lztfl1,Rai14,1110038F14Rik,Akt3,Il4ra,Pgm1,Col18a1,Smc5,Mxd1,Itga4,Ebi3,Dusp14,Gng12,Apaf1,Enpp4,Adam19 |
| 4.623e-02 | -3.07 | GSE15330_WT_VS_IKAROS_KO_HSC_DN | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_HSC_DN | 178 | 21 | 15632 | 1249 |
Hdac1,Snx2,Etv6,Pcx,Oaf,Stat3,Sap30,Slc44a1,Slc15a3,Zc3h12c,Plekha2,Atp6v1d,Dync1h1,Gja1,Nlgn2,Lrrc8c,Tab2,Kat2b,Rab20,Cxcl10,Kif5c |
| 4.641e-02 | -3.07 | negative chemotaxis | biological process | GO:0050919 | 49 | 7 | 20694 | 1406 |
Nrp2,Sema3c,Itgav,Flrt3,Sema4c,Flrt2,Sema4a |
| 4.641e-02 | -3.07 | negative regulation of lipid biosynthetic process | biological process | GO:0051055 | 49 | 7 | 20694 | 1406 |
Bmp2,Trib3,Gfi1,Nfkb1,Sirt1,Sphk1,Pdgfb |
| 4.641e-02 | -3.07 | phospholipid translocation | biological process | GO:0045332 | 49 | 7 | 20694 | 1406 |
Abcc1,Xkr8,Atp11a,Atp11b,Plscr1,Abcb1a,Atp10a |
| 4.641e-02 | -3.07 | hair cell differentiation | biological process | GO:0035315 | 49 | 7 | 20694 | 1406 |
Triobp,Slc4a7,Sec24b,Jag1,Notch1,Clic5,Gfi1 |
| 4.656e-02 | -3.07 | GO_ENZYME_INHIBITOR_ACTIVITY | MSigDB lists | GO_ENZYME_INHIBITOR_ACTIVITY | 327 | 35 | 15632 | 1249 |
Atp2b4,Crim1,Spred1,Notch1,Socs1,Pttg1,Kat2b,Rhoh,Cdkn2d,Nck1,Prdx5,Cish,Spry2,Casp3,Birc2,Nlrc4,Timp1,Flrt3,Cst7,Ppp1r14b,Cdkn1a,Socs7,Prkar2b,Serpinb2,Serpinb9,Trib1,Trib3,C3,Socs3,Spint2,Slpi,Serpine1,Flrt2,Tnfsf14,Birc3 |
| 4.658e-02 | -3.07 | regulation of actin filament bundle assembly | biological process | GO:0032231 | 103 | 12 | 20694 | 1406 |
Sdc4,Rhoc,Evl,Met,Plek,Swap70,Lpar1,Carmil1,Rgcc,Cx3cl1,Ptger4,Asap3 |
| 4.661e-02 | -3.07 | GO_DETOXIFICATION | MSigDB lists | GO_DETOXIFICATION | 69 | 10 | 15632 | 1249 |
Txnrd1,Sod2,Hp,Slc30a1,Ptgs2,Prdx1,Srxn1,Nqo1,Prdx5,Gsr |
| 4.661e-02 | -3.07 | GO_CLATHRIN_COATED_VESICLE_MEMBRANE | MSigDB lists | GO_CLATHRIN_COATED_VESICLE_MEMBRANE | 69 | 10 | 15632 | 1249 |
Ldlr,Fcgr1,H2-Aa,Dbnl,Aftph,Ap3b1,H2-Eb1,H2-Ab1,Cd74,Fzd5 |
| 4.661e-02 | -3.07 | MODULE_358 | MSigDB lists | MODULE_358 | 69 | 10 | 15632 | 1249 |
Nfkbid,Tagap,Cd164,G3bp2,Cd69,Syne2,Orai2,Peli1,Irs2,Crkl |
| 4.670e-02 | -3.06 | mouse chr11 C|11 | chromosome location | mouse chr11 C|11 | 6 | 2 | 24173 | 1464 |
Heatr9,Wfdc17 |
| 4.670e-02 | -3.06 | mouse chr4 D2.2|4 63.26 cM | chromosome location | mouse chr4 D2.2|4 63.26 cM | 6 | 2 | 24173 | 1464 |
Hdac1,Marcksl1 |
| 4.670e-02 | -3.06 | mouse chr8 A4|8 23.89 cM | chromosome location | mouse chr8 A4|8 23.89 cM | 6 | 2 | 24173 | 1464 |
Msr1,Slc7a2 |
| 4.670e-02 | -3.06 | mouse chr5 E1|5 44.78 cM | chromosome location | mouse chr5 E1|5 44.78 cM | 6 | 2 | 24173 | 1464 |
Cxcl2,Cxcl1 |
| 4.672e-02 | -3.06 | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | MSigDB lists | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | 199 | 23 | 15632 | 1249 |
Chd9,Ust,Ptges,Rcl1,Smox,Asb13,Flnb,Slc7a5,Hk2,Degs2,P2ry2,Tsku,Olfml3,Hck,Mcm10,Cdk5r1,Cish,Gpr68,Ifrd1,Ccnd1,Srm,Slc2a1,Tiparp |
| 4.674e-02 | -3.06 | artery morphogenesis | biological process | GO:0048844 | 70 | 9 | 20694 | 1406 |
Cited2,Prdm1,Ptger4,Sec24b,Pdgfrb,Acvrl1,Jag1,Notch1,Ldlr |
| 4.674e-02 | -3.06 | modification by host of symbiont morphology or physiology | biological process | GO:0051851 | 70 | 9 | 20694 | 1406 |
Zc3h12a,Ccl4,Trem1,Rab9,Hdac1,Pf4,Ccl5,Pcx,Jun |
| 4.678e-02 | -3.06 | 14-3-3 protein binding | molecular function | GO:0071889 | 29 | 5 | 20217 | 1400 |
Zfp36,Ksr1,Prkce,Ddit4,Irs2 |
| 4.681e-02 | -3.06 | protein processing | biological process | GO:0016485 | 161 | 17 | 20694 | 1406 |
Sde2,Plau,Myc,Cpd,Casp7,Casp8,Mmp14,Casp1,Casp2,C1ra,Casp3,Ptch1,Plat,C1rl,Srgn,Ripk2,Pgk1 |
| 4.683e-02 | -3.06 | GO_REGULATION_OF_GLIOGENESIS | MSigDB lists | GO_REGULATION_OF_GLIOGENESIS | 88 | 12 | 15632 | 1249 |
P2ry12,Mecp2,Csf1,Stap1,Lyn,Lif,Notch1,Etv5,Il1b,Clcf1,Bmp2,Tspo |
| 4.687e-02 | -3.06 | serine biosynthesis | BIOCYC pathways | MOUSE_SERSYN-PWY | 4 | 2 | 1025 | 97 |
Phgdh,Psat1 |
| 4.687e-02 | -3.06 | D-myo-inositol (1,3,4)-trisphosphate biosynthesis | BIOCYC pathways | MOUSE_PWY-6364 | 4 | 2 | 1025 | 97 |
Itpkc,Minpp1 |
| 4.694e-02 | -3.06 | GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 349 | 37 | 15632 | 1249 |
Eno2,Pde4b,Hk1,Ampd3,Oas1a,Pde7b,Hk2,Oas2,Adora2a,Ldha,Oas1g,Dck,Ak4,Pfkl,Pgk1,Htr2b,Il1b,Acpp,Eno1,Hspa1a,Cycs,Rhoq,Pde1b,Pnp2,Mecp2,Pde5a,Tpi1,Mthfr,Calcrl,Papss2,Slc25a25,Pfkfb3,Pde3b,Enpp4,Hk3,Gda,Samhd1 |
| 4.696e-02 | -3.06 | BCAT_BILD_ET_AL_DN | MSigDB lists | BCAT_BILD_ET_AL_DN | 42 | 7 | 15632 | 1249 |
Tnfaip3,Gclm,Irak2,Plagl1,Il1a,Zfp281,Lnpep |
| 4.696e-02 | -3.06 | RIZ_ERYTHROID_DIFFERENTIATION_12HR | MSigDB lists | RIZ_ERYTHROID_DIFFERENTIATION_12HR | 42 | 7 | 15632 | 1249 |
Keap1,Jun,Nr1h3,Notch1,Fos,Egr1,Klf6 |
| 4.696e-02 | -3.06 | SUNG_METASTASIS_STROMA_DN | MSigDB lists | SUNG_METASTASIS_STROMA_DN | 42 | 7 | 15632 | 1249 |
Ltbp2,Mcm6,Serpine1,Pnp2,Dek,Mcmbp,G3bp2 |
| 4.696e-02 | -3.06 | ZHAN_MULTIPLE_MYELOMA_PR_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_PR_DN | 42 | 7 | 15632 | 1249 |
Socs1,Arid5b,Kat2b,Rsbn1,Syne2,Zhx2,Mob3c |
| 4.696e-02 | -3.06 | PID_ERBB2_ERBB3_PATHWAY | MSigDB lists | PID_ERBB2_ERBB3_PATHWAY | 42 | 7 | 15632 | 1249 |
Jak2,Stat3,Fos,Pik3cd,Jun,Map2k1,Src |
| 4.696e-02 | -3.06 | MODULE_284 | MSigDB lists | MODULE_284 | 42 | 7 | 15632 | 1249 |
Osbpl3,Kdr,Chd9,Phlda1,Inpp1,Igf1r,Nr4a3 |
| 4.696e-02 | -3.06 | GO_RESPONSE_TO_ELECTRICAL_STIMULUS | MSigDB lists | GO_RESPONSE_TO_ELECTRICAL_STIMULUS | 42 | 7 | 15632 | 1249 |
Src,Psmb9,Hif1a,Slc9a1,Btg2,Il6,Cd14 |
| 4.698e-02 | -3.06 | ATACCTC_MIR202 | MSigDB lists | ATACCTC_MIR202 | 168 | 20 | 15632 | 1249 |
Armc8,Gtpbp2,Xrn1,Cyth3,Tab2,Ccnd2,Trib1,Rnf139,Hmgcs1,Cpeb4,Slc30a4,Hk2,Mmd,Ccnd1,Pnp2,Btg2,Il10,Zswim4,Dusp1,4930523C07Rik |
| 4.705e-02 | -3.06 | negative regulation of organelle organization | biological process | GO:0010639 | 384 | 35 | 20694 | 1406 |
Swap70,Ier3,Sirt1,Bnip3,Chmp4b,Pttg1,Bcor,Tmem67,Dbnl,Trip13,Nupr1,Myadm,Rgcc,Psmd10,Tlr2,Tmsb10,Kat2b,Osm,Src,Met,H3f3b,Dcp2,Evl,Pml,Jarid2,Mllt6,Cenpe,Higd1a,Atm,Kdm4a,Lif,Mid1,Tmod3,Tspo,Mul1 |
| 4.707e-02 | -3.06 | regulation of postsynapse organization | biological process | GO:0099175 | 126 | 14 | 20694 | 1406 |
Cdk5r1,Srgn,Lrp8,Slc7a11,Lrp4,Homer1,Sipa1l1,Crkl,Dbnl,Fcgr2b,Chmp4b,Prnp,Arf4,Nrp2 |
| 4.709e-02 | -3.06 | modification-dependent protein catabolic process | biological process | GO:0019941 | 474 | 42 | 20694 | 1406 |
Dnajb2,Uchl1,Tnfaip3,Tmem67,Birc2,Crbn,Usp18,Znrf1,Cnot4,Isg15,Trim13,Cop1,Rnf19b,Sirt1,Psmb10,Spsb1,Arel1,Psmb6,Dtx3l,Mdm2,Ankib1,Psma6,Rnf14,Rffl,Usp42,Rnf34,Usp12,Znrf3,Usp25,Armc8,Uba7,Pml,Ubr4,Psmb8,Fbxo4,Peli1,Klhl25,Rnf19a,Ube2l6,Arrdc4,Psmb9,Bfar |
| 4.718e-02 | -3.05 | regulation of dendritic spine development | biological process | GO:0060998 | 92 | 11 | 20694 | 1406 |
Eif4g2,Lrp8,Cdk5r1,Lpar1,Sipa1l1,Nlgn2,Plk2,Dbnl,Mecp2,D16Ertd472e,Nr3c1 |
| 4.719e-02 | -3.05 | RGAANNTTC_HSF1_01 | MSigDB lists | RGAANNTTC_HSF1_01 | 404 | 42 | 15632 | 1249 |
Nfkbid,Spen,Bcl9,Asns,Lap3,Eif4g2,P4ha1,Gch1,Map4k4,Stip1,Cacna1d,Rgs1,Ralgds,Phf6,Irf1,Clec4d,Nr4a3,Egr3,Rtn1,Rbpms,Cept1,Dennd1b,Cish,Psmd10,Rhbdf2,Jun,Hspa1a,Trip10,Dnaja1,Bcl6,Dusp1,Hivep2,Ehd1,Hsph1,Abcc5,Mdfic,Me1,Tab2,Pikfyve,Jmjd6,Prdm1,Nek6 |
| 4.720e-02 | -3.05 | mouse chr5|5 E2 | chromosome location | mouse chr5|5 E2 | 23 | 4 | 24173 | 1464 |
G3bp2,U90926,Cxcl11,Ccng2 |
| 4.723e-02 | -3.05 | Ankyrin_rpt-contain_dom | interpro domains | IPR020683 | 222 | 23 | 19984 | 1430 |
Bcor,Uaca,Ankrd24,Asb13,Ankib1,Nfkb1,Cdkn2d,Psmd10,Notch2,Bcorl1,Nfkb2,Asap3,Abtb2,Rai14,Nfkbid,Nfkbie,Ankrd17,Nfkbib,Notch1,Nfkbia,Nfkbil1,Ppp1r12b,Nfkbiz |
| 4.729e-02 | -3.05 | RasGEF | pfam domains | PF00617 | 28 | 5 | 18711 | 1348 |
Rgl1,Rasgrp1,Rapgef5,Rapgef2,Ralgds |
| 4.729e-02 | -3.05 | zf-C3HC4 | pfam domains | PF00097 | 28 | 5 | 18711 | 1348 |
Dtx2,Traf5,Traf2,Trim30d,Trim21 |
| 4.730e-02 | -3.05 | regulation of insulin secretion involved in cellular response to glucose stimulus | biological process | GO:0061178 | 81 | 10 | 20694 | 1406 |
Prkce,Hmgn3,Pim3,Cacna1d,Klf7,Sirt1,Hif1a,Pde3b,Map4k4,Gpr68 |
| 4.738e-02 | -3.05 | CTCAGGG_MIR125B_MIR125A | MSigDB lists | CTCAGGG_MIR125B_MIR125A | 295 | 32 | 15632 | 1249 |
Mtus1,Zswim4,Abcc5,Lrp4,Txnrd1,Hivep2,Tlk2,Rhoq,Irf4,Stat3,Tbc1d1,Parp14,Sertad3,Abr,Prdm1,Ier2,Plagl2,Vcpip1,Cd34,Lnpep,Ccnj,Casp2,Etv6,Sh3bp4,Wars,Usp12,Rtn2,Asb13,Itga9,Sema4c,Fam53c,Gtpbp2 |
| 4.754e-02 | -3.05 | - | gene3d domains | 3.10.320.10 | 10 | 3 | 8819 | 755 |
H2-Aa,H2-Eb1,H2-Ab1 |
| 4.760e-02 | -3.04 | GO_NEGATIVE_REGULATION_OF_OSSIFICATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_OSSIFICATION | 60 | 9 | 15632 | 1249 |
Notch1,P2ry2,Ptch1,Adrb2,Hif1a,Bcor,Lrp4,Tnf,Ccr1 |
| 4.760e-02 | -3.04 | BEIER_GLIOMA_STEM_CELL_DN | MSigDB lists | BEIER_GLIOMA_STEM_CELL_DN | 60 | 9 | 15632 | 1249 |
Ccnd1,Klf7,Tle3,Bmp2,H2-Aa,Inpp1,Cd74,H2-Ab1,Nfkbiz |
| 4.764e-02 | -3.04 | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN | 158 | 19 | 15632 | 1249 |
Smg7,Zhx2,Mdfic,Plagl2,Tnfrsf14,Dtx2,Kpna3,Slc30a1,Scn1b,Tlr1,Errfi1,Hivep3,Cnot4,Agrn,Ikbkg,Src,Gadd45b,Zmynd15,Sco1 |
| 4.768e-02 | -3.04 | GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN | MSigDB lists | GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN | 189 | 22 | 15632 | 1249 |
Rac3,Dtx2,Mtmr14,Fam53c,Arrdc4,Ciapin1,Tnfsf10,Rhoc,Crim1,Csrp1,Cx3cr1,Ttc9c,Gpsm2,Dse,Pdlim7,Nr3c1,Trim14,Ikzf1,Mlkl,Nfkbie,Inhba,Ogfrl1 |
| 4.768e-02 | -3.04 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 189 | 22 | 15632 | 1249 |
Jmjd6,Mthfd2,Serpinb9,Cd200,Ppa1,Tpi1,Dck,Ptger4,Wdr43,Fam162a,Idi1,Clic4,Irf8,Srm,Sod2,Tnf,Hk2,Gadd45g,Trip13,Plscr1,Irf4,Gclm |
| 4.768e-02 | -3.04 | GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN | MSigDB lists | GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN | 189 | 22 | 15632 | 1249 |
Mcm10,Ccnd2,Mcm6,Pigv,Il4ra,Ldlr,Slc16a1,Stip1,Prpf4,Txnrd1,Asns,Gem,Rrs1,Eno1,Ggct,Cish,Trip13,Pdss1,Slc39a14,Mmd,Cd69,Eef1e1 |
| 4.768e-02 | -3.04 | CREB_Q4_01 | MSigDB lists | CREB_Q4_01 | 189 | 22 | 15632 | 1249 |
Arg2,Relb,Rbms2,Slc25a25,Cenpe,Dusp1,Mllt6,Ccdc86,Rhoq,Egr2,Rcan1,Trib1,Ldha,Ppp2r2a,Dio2,Pkp4,Lmo4,Fosb,Gem,Ppp1r15a,Maff,Noc4l |
| 4.777e-02 | -3.04 | regulation of transporter activity | biological process | GO:0032409 | 271 | 26 | 20694 | 1406 |
Slc9a1,Cox17,Adrb2,Tlr9,Cacnb3,Prnp,Gpr35,Ccl2,Stoml1,Hap1,Gem,Glrx,Scn1b,Abcb1a,Ptafr,Cacna1d,Pde4b,Actb,Mmp9,Agrn,Hspa2,Nlgn2,Gja1,Homer1,Cav1,Hk1 |
| 4.784e-02 | -3.04 | ETS_DOMAIN_3 | prosite domains | PS50061 | 26 | 5 | 13278 | 1037 |
Etv3,Spic,Etv5,Ets2,Etv6 |
| 4.786e-02 | -3.04 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP | 51 | 8 | 15632 | 1249 |
Cycs,Cxcl1,Trp53i11,Sgcb,Itgb8,H2-Aa,Daxx,Glrx |
| 4.786e-02 | -3.04 | GO_KINASE_ACTIVATOR_ACTIVITY | MSigDB lists | GO_KINASE_ACTIVATOR_ACTIVITY | 51 | 8 | 15632 | 1249 |
Cdkn1a,Daxx,Mark2,Spry2,Map2k1,Cdk5r1,Ccl5,Malt1 |
| 4.786e-02 | -3.04 | GO_REGULATION_OF_DNA_RECOMBINATION | MSigDB lists | GO_REGULATION_OF_DNA_RECOMBINATION | 51 | 8 | 15632 | 1249 |
Ppp4r2,Clcf1,Cd40,Bcl6,Il10,Fignl2,Prdm9,Tnfsf4 |
| 4.786e-02 | -3.04 | GO_STEROL_HOMEOSTASIS | MSigDB lists | GO_STEROL_HOMEOSTASIS | 51 | 8 | 15632 | 1249 |
Med13,Lipg,Ldlr,Sirt1,Ehd1,Fabp3,Nr1h3,Cav1 |
| 4.786e-02 | -3.04 | GO_POSITIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION | 51 | 8 | 15632 | 1249 |
Sphk1,Jun,Cd74,Pml,Cdkn1a,Pdgfc,Myc,Pdgfb |
| 4.819e-02 | -3.03 | GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_DN | MSigDB lists | GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_DN | 148 | 18 | 15632 | 1249 |
Tagln,Irf8,Ggct,Prkce,Sirt1,Casp7,St3gal1,Csrnp1,Dnaja2,Smc5,Pim1,Adrb2,Crlf3,Sgk3,Jak2,Idi1,Sla,Stard7 |
| 4.819e-02 | -3.03 | growth factor activity | molecular function | GO:0008083 | 147 | 16 | 20217 | 1400 |
Osm,Osgin2,Cxcl1,Gdf15,Pdgfc,Pdgfb,Csf3,Kitl,Timp1,Vegfc,Inhba,Il6,Bmp2,Csf1,Il12b,Lif |
| 4.822e-02 | -3.03 | CLECT | smart domains | SM00034 | 119 | 16 | 9567 | 823 |
Vcan,Ly75,Clec4n,Klrk1,Layn,Sele,Clec5a,Klra2,Clec4e,Cd302,Sell,Clec2d,Olr1,Clec4a1,Clec4d,Cd69 |
| 4.822e-02 | -3.03 | small molecule biosynthetic process | biological process | GO:0044283 | 449 | 40 | 20694 | 1406 |
Syk,Upp1,Ptafr,Mthfr,Phgdh,Ptgs2,Gpd2,Dse,Psat1,Ldha,Itpkc,Asns,Hsd17b7,Cnp,Atf3,Tpi1,Asah2,Ass1,Pla2g4a,Gch1,Samhd1,Sphk1,Hmgcs1,Edn1,Ptges,Pgk1,Pcx,Plcl2,Pde5a,Plod3,Lipg,Tha1,Mthfd1l,Plod2,Cd74,Pdss1,Dhrs9,Nr1h3,Kmo,Il1b |
| 4.829e-02 | -3.03 | Band_41_domain | interpro domains | IPR019749 | 47 | 7 | 19984 | 1430 |
Frmd4a,Myo10,Frmd6,Ptk2,Ezr,Tyk2,Jak2 |
| 4.829e-02 | -3.03 | FERM_2 | interpro domains | IPR035963 | 47 | 7 | 19984 | 1430 |
Myo10,Frmd4a,Ezr,Ptk2,Jak2,Tyk2,Frmd6 |
| 4.836e-02 | -3.03 | ZHANG_TLX_TARGETS_60HR_UP | MSigDB lists | ZHANG_TLX_TARGETS_60HR_UP | 274 | 30 | 15632 | 1249 |
Slco3a1,Sphk1,Pdgfc,Apaf1,Tap1,Fos,Cited2,Gadd45b,Nr4a1,Klf6,Mdm2,Nqo1,Gadd45g,Sat1,Cp,Dusp8,Rai14,Rnf145,Smox,Cpeb4,Parp3,Cdkn1a,Sp110,Trafd1,Cflar,Ralgds,Ddit4,Csf1,Srxn1,Btg2 |
| 4.839e-02 | -3.03 | Longevity regulating pathway - multiple species | KEGG pathways | ko04213 | 62 | 10 | 7931 | 713 |
Hspa2,Igf1r,Hspa1a,Akt3,Hspa1b,Sod2,Sirt1,Hdac1,Pik3cd,Irs2 |
| 4.839e-02 | -3.03 | Longevity regulating pathway - multiple species | KEGG pathways | mmu04213 | 62 | 10 | 7931 | 713 |
Igf1r,Hspa2,Hspa1a,Akt3,Hspa1b,Sirt1,Sod2,Pik3cd,Hdac1,Irs2 |
| 4.840e-02 | -3.03 | IG | smart domains | SM00409 | 377 | 42 | 9567 | 823 |
Fcgr1,Cd80,Milr1,Fcgr2b,B430306N03Rik,Pdgfrb,Mfap3l,Igsf8,Clmp,Axl,Vcan,Igsf9,Sema4c,Tarm1,Gm5150,Slamf9,Trem1,Il18rap,Cd200r4,Cd300lf,Nectin4,Cd200,Treml2,Icam1,Icosl,Treml4,Nectin2,Sema3c,Malt1,F11r,Pvr,Kdr,Cd274,Vcam1,Cd300e,Fcgr4,Siglece,Tapbpl,Palld,Cd83,A530064D06Rik,Flt1 |
| 4.841e-02 | -3.03 | regulation of response to drug | biological process | GO:2001023 | 115 | 13 | 20694 | 1406 |
Il10,Txn1,Glrx,Hsph1,Htr2a,Met,Hk3,Tnf,Adora2a,Nr4a3,Abcb1a,Ptger4,Arg2 |
| 4.859e-02 | -3.02 | GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_UP | MSigDB lists | GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_UP | 138 | 17 | 15632 | 1249 |
Gfpt1,Fbxo4,Ikbke,Pgk1,Malt1,Tpi1,Ube2l6,Isg20,Phlpp2,Errfi1,Mdm2,Fam43a,Tshz1,Psip1,Asns,Rbbp8,Tcf4 |
| 4.860e-02 | -3.02 | GSE3982_MAST_CELL_VS_TH1_UP | MSigDB lists | GSE3982_MAST_CELL_VS_TH1_UP | 179 | 21 | 15632 | 1249 |
Rtn2,Ly75,Procr,Tdrd7,Spint2,Plekhf2,Ass1,Rabgef1,Morc3,Fcgr4,Dpy19l1,Plat,Tmem123,Pilra,Pmepa1,Ptk2,Dram1,Hp,Ptafr,Trim13,Phyh |
| 4.860e-02 | -3.02 | GSE40685_NAIVE_CD4_TCELL_VS_FOXP3_KO_TREG_PRECURSOR_UP | MSigDB lists | GSE40685_NAIVE_CD4_TCELL_VS_FOXP3_KO_TREG_PRECURSOR_UP | 179 | 21 | 15632 | 1249 |
Ccnd2,Ptprj,Ripk3,Mdfic,Nfxl1,Ccl4,Cd86,Swap70,Vps54,Gem,D16Ertd472e,Ehd1,N4bp1,Tshz1,Cd200r4,Slc39a14,Hk2,Nqo1,Rap1gap2,Ctsc,Pdss1 |
| 4.860e-02 | -3.02 | GSE2585_CTEC_VS_THYMIC_MACROPHAGE_DN | MSigDB lists | GSE2585_CTEC_VS_THYMIC_MACROPHAGE_DN | 179 | 21 | 15632 | 1249 |
Slc29a3,Smg7,Notch2,Zc3hav1,Myo10,Parp3,Znrf3,Coa5,Ms4a6d,Srxn1,Dock10,Mdm2,Lnpep,Ahrr,Tuba4a,Rabgef1,Src,Cited2,Itgal,Cav1,Daam1 |
| 4.860e-02 | -3.02 | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_UP | MSigDB lists | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_UP | 179 | 21 | 15632 | 1249 |
Pkp4,Igf1r,Jak2,Asf1a,Ikbke,Hif1a,Frmd4a,Nfkbiz,Parp3,Ap3b1,Optn,Egln3,Stx6,Ddit4,Zeb1,Tor1aip2,Cacybp,Plod2,Casp4,Nfkbia,Sod2 |
| 4.860e-02 | -3.02 | GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | 179 | 21 | 15632 | 1249 |
Etv3,Il1a,Dtwd1,Ptk2,Plk3,Csrnp1,Ell2,Stip1,Agpat4,Ripk3,Hk3,Ppp2r2a,Pde3b,Clic4,Fubp1,Rims3,Cdyl,Gypc,Pde5a,Hat1,Maff |
| 4.860e-02 | -3.02 | GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN | MSigDB lists | GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN | 179 | 21 | 15632 | 1249 |
Nxf1,St3gal6,Ciapin1,Mppe1,Tnfaip3,H3f3b,Rgs1,Casp4,Daam1,Bcl2l11,Eif4g2,Junb,Pde4b,Syne2,Uba7,Dusp8,Ifi44,Fchsd2,Ext1,Isg20,Btg2 |
| 4.860e-02 | -3.02 | GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN | MSigDB lists | GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN | 179 | 21 | 15632 | 1249 |
Evl,Cdkn2d,Slfn3,Trp53i11,Tnip1,Slc16a1,Hvcn1,Rcl1,Plaur,Gbp2,Tuba4a,Sesn3,Cnp,Slfn4,Rhof,Rffl,Ppp2r5a,Slc39a4,Mllt6,Treml2,Pou2f2 |
| 4.860e-02 | -3.02 | GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN | MSigDB lists | GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN | 179 | 21 | 15632 | 1249 |
4933430I17Rik,Nlrc5,Myadm,Acpp,Rbbp8,Casp8,Trim14,Ppp2r5a,Chst11,Cd200r4,Rnf19a,Tmem176a,Vasp,Ythdf1,Marcksl1,Prdm1,Lif,Dck,Nod1,Vegfc,Mvp |
| 4.860e-02 | -3.02 | GSE27859_DC_VS_CD11C_INT_F480_INT_DC_UP | MSigDB lists | GSE27859_DC_VS_CD11C_INT_F480_INT_DC_UP | 179 | 21 | 15632 | 1249 |
Pgs1,Prdm1,4930453N24Rik,Il4ra,Nr1h3,Klf7,Dusp16,Slc37a3,Apaf1,Junb,Jarid2,Pde4b,Stat5a,Slc13a3,Itgal,Ptpn2,Serpine1,Stat3,Pdgfb,Rnf19a,Tyk2 |
| 4.860e-02 | -3.02 | VEGF_A_UP.V1_DN | MSigDB lists | VEGF_A_UP.V1_DN | 179 | 21 | 15632 | 1249 |
Ccne1,Flt1,Slc4a7,Cenpe,Rrs1,Slc7a2,Mmp14,Il6,Ccdc86,Sat1,D1Ertd622e,Mdn1,Mafk,Lrp8,Tgfbi,Serpinb2,Cdc42ep2,Rnd3,Pcdh7,Tle3,Vegfc |
| 4.860e-02 | -3.02 | GSE7831_1H_VS_4H_CPG_STIM_PDC_UP | MSigDB lists | GSE7831_1H_VS_4H_CPG_STIM_PDC_UP | 179 | 21 | 15632 | 1249 |
Tnfaip2,Pbx1,Fscn1,Trafd1,Pml,Tlr3,Nxf1,Etv3,Pttg1,Plscr1,Sat1,Zc3h7a,Ociad1,Wdfy1,Rsad2,Treml2,Rin2,Gch1,Ankib1,Birc2,Mtus1 |
| 4.860e-02 | -3.02 | GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN | 179 | 21 | 15632 | 1249 |
Pbx1,Rsbn1,Znrf1,Crlf3,Fam102b,Rab3ip,Rhoh,Rab20,Mppe1,Etv3,Pde1b,Slpi,Prkce,Cnn3,Sat1,Gpr132,Rasgrp1,Kremen1,Card6,Tagln,Rgs14 |
| 4.869e-02 | -3.02 | Unc5b (unc-5 netrin receptor B) | protein interactions | 107449 | 9 | 3 | 7778 | 753 |
Ppp2r1b,Flrt2,Flrt3 |
| 4.869e-02 | -3.02 | RPL17 (ribosomal protein L17) | protein interactions | 6139 | 9 | 3 | 7778 | 753 |
Rrbp1,Ksr1,Brwd3 |
| 4.869e-02 | -3.02 | Lmo4 (LIM domain only 4) | protein interactions | 16911 | 9 | 3 | 7778 | 753 |
Lmo4,Socs3,Jak2 |
| 4.869e-02 | -3.02 | SORBS2 (sorbin and SH3 domain containing 2) | protein interactions | 8470 | 9 | 3 | 7778 | 753 |
Tmod3,Flnb,Actb |
| 4.869e-02 | -3.02 | Casp8 (caspase 8) | protein interactions | 12370 | 9 | 3 | 7778 | 753 |
Sqstm1,Fas,Il1b |
| 4.869e-02 | -3.02 | MYO6 (myosin VI) | protein interactions | 4646 | 9 | 3 | 7778 | 753 |
Actb,Itga5,Tmod3 |
| 4.869e-02 | -3.02 | Psme3 (proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)) | protein interactions | 19192 | 9 | 3 | 7778 | 753 |
Casp7,Klf2,Casp3 |
| 4.869e-02 | -3.02 | CDK2 (cyclin dependent kinase 2) | protein interactions | 1017 | 9 | 3 | 7778 | 753 |
Ifi211,Mdm2,Samhd1 |
| 4.869e-02 | -3.02 | MVP (major vault protein) | protein interactions | 9961 | 9 | 3 | 7778 | 753 |
Ptpn2,Chmp4b,Actb |
| 4.869e-02 | -3.02 | Rnf11 (ring finger protein 11) | protein interactions | 29864 | 9 | 3 | 7778 | 753 |
Tnfaip3,Tax1bp1,Traf2 |
| 4.869e-02 | -3.02 | NOP2 (NOP2 nucleolar protein) | protein interactions | 4839 | 9 | 3 | 7778 | 753 |
Ktn1,Rrbp1,Ksr1 |
| 4.869e-02 | -3.02 | IPO4 (importin 4) | protein interactions | 79711 | 9 | 3 | 7778 | 753 |
Ksr1,Tpx2,Cenpe |
| 4.872e-02 | -3.02 | Regulation of insulin secretion | REACTOME pathways | R-MMU-422356 | 72 | 11 | 8608 | 757 |
Gng11,Gnb4,Stxbp1,Marcks,Gng12,Gng4,Slc2a1,Cacna1d,Itpr1,Cacnb3,Gna15 |
| 4.874e-02 | -3.02 | transport along microtubule | biological process | GO:0010970 | 150 | 16 | 20694 | 1406 |
Rasgrp1,Map2k1,Hap1,Rab21,Ift22,Ift57,Ap3b1,Uchl1,Syne2,Kif5c,Dync1h1,Hif1a,Kif3c,Stau1,Dst,Ap3m2 |
| 4.879e-02 | -3.02 | GBD_FH3 | prosite domains | PS51232 | 11 | 3 | 13278 | 1037 |
Daam1,Fmnl2,Diaph2 |
| 4.879e-02 | -3.02 | HSP70_2 | prosite domains | PS00329 | 11 | 3 | 13278 | 1037 |
Hspa1b,Hspa1a,Hspa2 |
| 4.879e-02 | -3.02 | LY6_UPAR | prosite domains | PS00983 | 11 | 3 | 13278 | 1037 |
Ly6c2,Ly6a,Plaur |
| 4.882e-02 | -3.02 | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | 128 | 16 | 15632 | 1249 |
Irak2,Sec24a,Gfpt1,Sh3bgrl2,Myo10,Cd164,Gda,Ell2,Etnk1,F11r,Nqo1,Cpd,Slc39a14,Plac8,Fzd5,Higd1a |
| 4.882e-02 | -3.02 | WWTAAGGC_UNKNOWN | MSigDB lists | WWTAAGGC_UNKNOWN | 128 | 16 | 15632 | 1249 |
Rbms1,Rbms2,Slc16a1,Etv5,Dusp5,Kdm4a,Sdc1,Cycs,Pdlim7,Bbx,Ube2e2,Vasp,Cnn2,Jdp2,Sesn3,Klf2 |
| 4.882e-02 | -3.02 | GO_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | 118 | 15 | 15632 | 1249 |
Il1b,Pbx1,Sphk1,Phip,Il1a,Smc5,Tmod3,Mdm2,Ccnd1,Ube2e2,Pdgfb,Edn1,Ankrd17,Pdgfrb,Asns |
| 4.882e-02 | -3.02 | NRL_DN.V1_DN | MSigDB lists | NRL_DN.V1_DN | 118 | 15 | 15632 | 1249 |
Casp7,Prdm1,Socs3,Usp25,St3gal3,Kif5c,Adrb2,Clic4,Nr4a1,Nfkb1,Ccl12,Fabp7,Bbx,Pnp2,Slamf9 |
| 4.886e-02 | -3.02 | SEIDEN_ONCOGENESIS_BY_MET | MSigDB lists | SEIDEN_ONCOGENESIS_BY_MET | 79 | 11 | 15632 | 1249 |
Cers6,Hat1,Serp1,Plod2,Higd1a,P4ha1,Tcea1,Clic4,Tmem123,Aida,Stat1 |
| 4.886e-02 | -3.02 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | 79 | 11 | 15632 | 1249 |
Kdr,Crim1,Igf1r,Acvr1b,Nrp2,Acvr1,Acvrl1,Met,Flt1,Axl,Pdgfrb |
| 4.886e-02 | -3.02 | TCTGGAC_MIR198 | MSigDB lists | TCTGGAC_MIR198 | 79 | 11 | 15632 | 1249 |
Phf6,Tcea1,Pbx1,Slc2a1,Hmga1,Msr1,Tshz1,Met,Ap3b1,Stoml1,Fut8 |
| 4.911e-02 | -3.01 | regulation of chromatin organization | biological process | GO:1902275 | 198 | 20 | 20694 | 1406 |
Pml,Mllt6,Gfi1,Jarid2,Parp10,Arid5a,Tlk2,Bcl6,Sirt1,Kat2b,Jdp2,Daxx,Nsd3,Kdm4a,Lif,Mecp2,Atm,Resf1,Mthfr,Bcor |
| 4.913e-02 | -3.01 | cytoskeleton-dependent intracellular transport | biological process | GO:0030705 | 162 | 17 | 20694 | 1406 |
Uchl1,Syne2,Ap3b1,Stau1,Ap3m2,Dst,Dync1h1,Hif1a,Kif3c,Kif5c,Rab21,Hap1,Ccdc88b,Map2k1,Rasgrp1,Ift22,Ift57 |
| 4.915e-02 | -3.01 | regulation of kidney development | biological process | GO:0090183 | 60 | 8 | 20694 | 1406 |
Lif,Pdgfb,Myc,Mmp9,Pdgfrb,Cflar,Egr1,Prkx |
| 4.915e-02 | -3.01 | ribonucleoside diphosphate metabolic process | biological process | GO:0009185 | 60 | 8 | 20694 | 1406 |
Hk1,Hk3,Ampd3,Pfkl,Hk2,Tpi1,Eno2,Pgk1 |
| 4.915e-02 | -3.01 | cellular amino acid biosynthetic process | biological process | GO:0008652 | 60 | 8 | 20694 | 1406 |
Plod3,Tha1,Psat1,Mthfr,Asns,Plod2,Ass1,Phgdh |
| 4.915e-02 | -3.01 | negative regulation of blood pressure | biological process | GO:0045776 | 60 | 8 | 20694 | 1406 |
Ptafr,Ier3,Adrb2,Vegfc,Gch1,Ahr,Nos2,Sod2 |
| 4.919e-02 | -3.01 | ONKEN_UVEAL_MELANOMA_DN | MSigDB lists | ONKEN_UVEAL_MELANOMA_DN | 483 | 49 | 15632 | 1249 |
Arf4,Adrb2,Cd200,Mtmr14,Plscr1,Cnn3,Plod2,Cav1,Ednrb,Prpf4,Atp11b,Slc16a1,Gng11,Sdc4,Kat2b,Palld,Ift57,Bbx,Spry2,Tiparp,Crbn,Bambi,Gca,Nr4a3,Serpinb9,Dnaja2,Tlr1,Phlda1,Nrp2,Tmeff1,Med21,Slc7a8,Pde4b,Etv5,Pdgfc,Pbx1,Bfar,Cd83,St3gal6,Atp11a,Hspa2,Ccng2,Lztfl1,Ccnd1,Kdm5b,Rab11fip1,Serp1,Mtus1,Gypc |
| 4.920e-02 | -3.01 | PHLPP1 (PH domain and leucine rich repeat protein phosphatase 1) | protein interactions | 23239 | 4 | 2 | 7778 | 753 |
Max,Ppp2r3a |
| 4.920e-02 | -3.01 | MAP7 (microtubule associated protein 7) | protein interactions | 9053 | 4 | 2 | 7778 | 753 |
Cenpe,Chmp4b |
| 4.920e-02 | -3.01 | RAB14 (RAB14, member RAS oncogene family) | protein interactions | 51552 | 4 | 2 | 7778 | 753 |
Actb,Flnb |
| 4.920e-02 | -3.01 | GHR (growth hormone receptor) | protein interactions | 100009325 | 4 | 2 | 7778 | 753 |
Stat5a,Cish |
| 4.920e-02 | -3.01 | DNAJA3 (DnaJ heat shock protein family (Hsp40) member A3) | protein interactions | 9093 | 4 | 2 | 7778 | 753 |
Jak2,Ksr1 |
| 4.920e-02 | -3.01 | Casp1 (caspase 1) | protein interactions | 12362 | 4 | 2 | 7778 | 753 |
Il1b,Tnfaip3 |
| 4.920e-02 | -3.01 | RPL12 (ribosomal protein L12) | protein interactions | 6136 | 4 | 2 | 7778 | 753 |
Ksr1,Rrbp1 |
| 4.920e-02 | -3.01 | Ctla4 (cytotoxic T-lymphocyte-associated protein 4) | protein interactions | 12477 | 4 | 2 | 7778 | 753 |
Lyn,Jak2 |
| 4.920e-02 | -3.01 | Rabep1 (rabaptin, RAB GTPase binding effector protein 1) | protein interactions | 54189 | 4 | 2 | 7778 | 753 |
Rpgrip1l,Rabgef1 |
| 4.920e-02 | -3.01 | VARS (valyl-tRNA synthetase) | protein interactions | 7407 | 4 | 2 | 7778 | 753 |
Rrbp1,Ktn1 |
| 4.920e-02 | -3.01 | Unc5d (unc-5 netrin receptor D) | protein interactions | 210801 | 4 | 2 | 7778 | 753 |
Flrt3,Flrt2 |
| 4.920e-02 | -3.01 | POLDIP3 (DNA polymerase delta interacting protein 3) | protein interactions | 84271 | 4 | 2 | 7778 | 753 |
Max,Chmp4b |
| 4.920e-02 | -3.01 | Pdlim2 (PDZ and LIM domain 2) | protein interactions | 213019 | 4 | 2 | 7778 | 753 |
Stat4,Stat1 |
| 4.920e-02 | -3.01 | PSMD11 (proteasome 26S subunit, non-ATPase 11) | protein interactions | 5717 | 4 | 2 | 7778 | 753 |
Tor1aip1,Ksr1 |
| 4.920e-02 | -3.01 | Sh2d1b2 (SH2 domain containing 1B2) | protein interactions | 545378 | 4 | 2 | 7778 | 753 |
Lyn,Hck |
| 4.920e-02 | -3.01 | TBL3 (transducin beta like 3) | protein interactions | 10607 | 4 | 2 | 7778 | 753 |
Ktn1,Rrbp1 |
| 4.920e-02 | -3.01 | Kcnb1 (potassium voltage gated channel, Shab-related subfamily, member 1) | protein interactions | 16500 | 4 | 2 | 7778 | 753 |
Hspa1b,Cyfip1 |
| 4.920e-02 | -3.01 | Stat5b (signal transducer and activator of transcription 5B) | protein interactions | 20851 | 4 | 2 | 7778 | 753 |
Stat5a,Jak2 |
| 4.920e-02 | -3.01 | CUL4B (cullin 4B) | protein interactions | 8450 | 4 | 2 | 7778 | 753 |
Ksr1,Brwd3 |
| 4.920e-02 | -3.01 | MACO1 (macoilin 1) | protein interactions | 55219 | 4 | 2 | 7778 | 753 |
Cenpe,Ktn1 |
| 4.920e-02 | -3.01 | RARA (retinoic acid receptor alpha) | protein interactions | 5914 | 4 | 2 | 7778 | 753 |
Nr4a1,Gadd45b |
| 4.920e-02 | -3.01 | Thbs1 (thrombospondin 1) | protein interactions | 21825 | 4 | 2 | 7778 | 753 |
Thbs1,Myc |
| 4.920e-02 | -3.01 | SRRM2 (serine/arginine repetitive matrix 2) | protein interactions | 23524 | 4 | 2 | 7778 | 753 |
Ksr1,Ezr |
| 4.920e-02 | -3.01 | RPL35 (ribosomal protein L35) | protein interactions | 11224 | 4 | 2 | 7778 | 753 |
Rrbp1,Brwd3 |
| 4.920e-02 | -3.01 | Snx17 (sorting nexin 17) | protein interactions | 266781 | 4 | 2 | 7778 | 753 |
Lrp8,Ldlr |
| 4.920e-02 | -3.01 | Egfl7 (EGF-like domain 7) | protein interactions | 353156 | 4 | 2 | 7778 | 753 |
Notch2,Notch1 |
| 4.920e-02 | -3.01 | Tnip1 (TNFAIP3 interacting protein 1) | protein interactions | 57783 | 4 | 2 | 7778 | 753 |
Tnf,Tnfaip3 |
| 4.920e-02 | -3.01 | LRRFIP1 (LRR binding FLII interacting protein 1) | protein interactions | 9208 | 4 | 2 | 7778 | 753 |
Tmod3,Actb |
| 4.920e-02 | -3.01 | GTPBP2 (GTP binding protein 2) | protein interactions | 54676 | 4 | 2 | 7778 | 753 |
Rrbp1,Junb |
| 4.920e-02 | -3.01 | PALM (paralemmin) | protein interactions | 5064 | 4 | 2 | 7778 | 753 |
Tmod3,Flnb |
| 4.920e-02 | -3.01 | Pirb (paired Ig-like receptor B) | protein interactions | 18733 | 4 | 2 | 7778 | 753 |
Hck,Fgr |
| 4.920e-02 | -3.01 | Igk-V28 (immunoglobulin kappa chain variable 28 (V28)) | protein interactions | 16114 | 4 | 2 | 7778 | 753 |
Rel,Nfkb1 |
| 4.920e-02 | -3.01 | Slc2a4 (solute carrier family 2 (facilitated glucose transporter), member 4) | protein interactions | 20528 | 4 | 2 | 7778 | 753 |
Lnpep,Daxx |
| 4.920e-02 | -3.01 | NFE2L2 (nuclear factor, erythroid 2 like 2) | protein interactions | 4780 | 4 | 2 | 7778 | 753 |
Ube2e1,Keap1 |
| 4.920e-02 | -3.01 | RPS5 (ribosomal protein S5) | protein interactions | 6193 | 4 | 2 | 7778 | 753 |
Rrbp1,Ksr1 |
| 4.920e-02 | -3.01 | BCL2L1 (BCL2 like 1) | protein interactions | 598 | 4 | 2 | 7778 | 753 |
Hsph1,Bcl2l11 |
| 4.920e-02 | -3.01 | KATNB1 (katanin regulatory subunit B1) | protein interactions | 10300 | 4 | 2 | 7778 | 753 |
Dync1h1,Katna1 |
| 4.920e-02 | -3.01 | TNPO3 (transportin 3) | protein interactions | 23534 | 4 | 2 | 7778 | 753 |
Ppp2r3a,Junb |
| 4.920e-02 | -3.01 | Nol3 (nucleolar protein 3 (apoptosis repressor with CARD domain)) | protein interactions | 78688 | 4 | 2 | 7778 | 753 |
Casp8,Fas |
| 4.920e-02 | -3.01 | GEMIN4 (gem nuclear organelle associated protein 4) | protein interactions | 50628 | 4 | 2 | 7778 | 753 |
Ksr1,Rrbp1 |
| 4.920e-02 | -3.01 | Tcf21 (transcription factor 21) | protein interactions | 21412 | 4 | 2 | 7778 | 753 |
Pbx1,Hdac1 |
| 4.920e-02 | -3.01 | EEF1B2 (eukaryotic translation elongation factor 1 beta 2) | protein interactions | 1933 | 4 | 2 | 7778 | 753 |
Rrbp1,Ktn1 |
| 4.920e-02 | -3.01 | CHAF1A (chromatin assembly factor 1 subunit A) | protein interactions | 10036 | 4 | 2 | 7778 | 753 |
Chmp4b,Tpi1 |
| 4.920e-02 | -3.01 | MRPL38 (mitochondrial ribosomal protein L38) | protein interactions | 64978 | 4 | 2 | 7778 | 753 |
Brwd3,Cenpe |
| 4.920e-02 | -3.01 | Casp9 (caspase 9) | protein interactions | 12371 | 4 | 2 | 7778 | 753 |
Jun,Birc3 |
| 4.920e-02 | -3.01 | SAP30 (Sin3A associated protein 30) | protein interactions | 8819 | 4 | 2 | 7778 | 753 |
Max,Sinhcaf |
| 4.920e-02 | -3.01 | OSBPL3 (oxysterol binding protein like 3) | protein interactions | 26031 | 4 | 2 | 7778 | 753 |
Ktn1,Junb |
| 4.920e-02 | -3.01 | Unc5a (unc-5 netrin receptor A) | protein interactions | 107448 | 4 | 2 | 7778 | 753 |
Flrt2,Flrt3 |
| 4.920e-02 | -3.01 | CD40 (CD40 molecule) | protein interactions | 958 | 4 | 2 | 7778 | 753 |
Birc3,Traf2 |
| 4.920e-02 | -3.01 | TMUB1 (transmembrane and ubiquitin like domain containing 1) | protein interactions | 83590 | 4 | 2 | 7778 | 753 |
Rmdn3,Rrbp1 |
| 4.920e-02 | -3.01 | RPL31 (ribosomal protein L31) | protein interactions | 6160 | 4 | 2 | 7778 | 753 |
Ksr1,Brwd3 |
| 4.920e-02 | -3.01 | CNOT8 (CCR4-NOT transcription complex subunit 8) | protein interactions | 9337 | 4 | 2 | 7778 | 753 |
Zfp36,Tnks1bp1 |
| 4.920e-02 | -3.01 | Apbb1 (amyloid beta (A4) precursor protein-binding, family B, member 1) | protein interactions | 11785 | 4 | 2 | 7778 | 753 |
Prnp,Evl |
| 4.920e-02 | -3.01 | VAPA (VAMP associated protein A) | protein interactions | 9218 | 4 | 2 | 7778 | 753 |
Rmdn3,Actb |
| 4.920e-02 | -3.01 | FEM1B (fem-1 homolog B) | protein interactions | 10116 | 4 | 2 | 7778 | 753 |
Fas,Casp3 |
| 4.920e-02 | -3.01 | Ccl3 (chemokine (C-C motif) ligand 3) | protein interactions | 20302 | 4 | 2 | 7778 | 753 |
Ccr3,Ccr1 |
| 4.920e-02 | -3.01 | Jak3 (Janus kinase 3) | protein interactions | 16453 | 4 | 2 | 7778 | 753 |
Stat5a,Stat3 |
| 4.940e-02 | -3.01 | Gprotein-gamma | interpro domains | IPR001770 | 12 | 3 | 19984 | 1430 |
Gng12,Gng4,Gng11 |
| 4.940e-02 | -3.01 | TGFB_receptor | interpro domains | IPR000333 | 12 | 3 | 19984 | 1430 |
Acvrl1,Acvr1b,Acvr1 |
| 4.940e-02 | -3.01 | Znf_TRAF | interpro domains | IPR001293 | 12 | 3 | 19984 | 1430 |
Traf5,Traf2,Trafd1 |
| 4.940e-02 | -3.01 | Type_I_exporter | interpro domains | IPR039421 | 12 | 3 | 19984 | 1430 |
Tap2,Tap1,Abcb1a |
| 4.940e-02 | -3.01 | CD59_antigen_CS | interpro domains | IPR018363 | 12 | 3 | 19984 | 1430 |
Ly6a,Plaur,Ly6c2 |
| 4.946e-02 | -3.01 | GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN | MSigDB lists | GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN | 169 | 20 | 15632 | 1249 |
Rnf34,Pde3b,Tnfrsf14,Ripk3,Sec24b,Abr,Fas,Tab2,Tapbpl,Pdzd11,Akt3,Med13,Slc31a2,Arid4a,Ifnar1,Tuba4a,Sqstm1,Irf7,Ascc3,Casp8 |
| 4.946e-02 | -3.01 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 169 | 20 | 15632 | 1249 |
Sp110,Snn,Gca,Dr1,Zcchc2,Notch2,Pik3cd,Pikfyve,Fgr,Trim13,Usp25,Cdkn2d,Dyrk2,Aim2,Slc2a1,Daam1,Swap70,Rel,Snx10,Morc3 |
| 4.946e-02 | -3.01 | GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_DN | 169 | 20 | 15632 | 1249 |
Rhoh,Usp25,Evl,Traf1,Lox,Kcna3,Zfp281,Ccl22,Irf1,Angpt1,Sp140,Gch1,Clic5,Cx3cr1,Lipe,Irf7,Hopx,Dusp2,Il18rap,Optn |
| 4.946e-02 | -3.01 | WNT_UP.V1_UP | MSigDB lists | WNT_UP.V1_UP | 169 | 20 | 15632 | 1249 |
Ccl12,Gdf15,Fos,Lcn2,Slc7a2,P2ry2,Ccr3,Il6,Ccdc86,Rbpms,Dtnb,Fpr2,Cd74,Il12b,Sdc4,Mapkbp1,Clec4e,Snn,Xcr1,Olr1 |
| 4.958e-02 | -3.00 | response to zinc ion | biological process | GO:0010043 | 30 | 5 | 20694 | 1406 |
Slc30a4,Hvcn1,Mt1,Mt2,Ass1 |
| 4.958e-02 | -3.00 | negative regulation of protein tyrosine kinase activity | biological process | GO:0061099 | 30 | 5 | 20694 | 1406 |
Errfi1,Mvp,Ptpn2,Cav1,Fam72a |
| 4.958e-02 | -3.00 | regulation of odontogenesis | biological process | GO:0042481 | 30 | 5 | 20694 | 1406 |
Cd34,Bmp2,Edn1,Bcor,Csf1 |
| 4.958e-02 | -3.00 | negative regulation of heart growth | biological process | GO:0061117 | 30 | 5 | 20694 | 1406 |
Jarid2,Cited2,Tomm70a,Sav1,Gja1 |
| 4.958e-02 | -3.00 | regulation of amyloid-beta formation | biological process | GO:1902003 | 30 | 5 | 20694 | 1406 |
Gsap,Hap1,Prnp,Tnf,Casp3 |
| 4.958e-02 | -3.00 | negative regulation of cardiac muscle tissue growth | biological process | GO:0055022 | 30 | 5 | 20694 | 1406 |
Sav1,Gja1,Tomm70a,Jarid2,Cited2 |
| 4.958e-02 | -3.00 | regulation of execution phase of apoptosis | biological process | GO:1900117 | 30 | 5 | 20694 | 1406 |
Rffl,Il6,Apaf1,Rnf34,Zc3h12a |
| 4.960e-02 | -3.00 | TYR_PHOSPHATASE_2 | prosite domains | PS50056 | 81 | 11 | 13278 | 1037 |
Dusp28,Dusp1,Dusp8,Dusp5,Ptprj,Dusp16,Dusp4,Dusp2,Dusp6,Dusp14,Ptpn2 |
| 4.974e-02 | -3.00 | plasma membrane bounded cell projection morphogenesis | biological process | GO:0120039 | 476 | 42 | 20694 | 1406 |
Palld,Actb,Itga4,Notch1,Agrn,Ptk2,Flrt3,Ptch1,Tsku,Ntng2,Gja1,Ext1,Igf1r,Dbnl,Cdk5r1,Nr4a3,Lrp8,Rab10,Flrt2,Uchl1,Klf7,Evl,Lhx2,Map4k4,Nrp2,Sema3c,Dock10,Map2k1,Sdc2,Sema4a,Cnp,Kdr,Egr2,Kif5c,Stxbp1,Cyfip1,Scn1b,Dst,Adora2a,Snx2,Lrp4,Vasp |
| 4.980e-02 | -3.00 | PCP/CE pathway | REACTOME pathways | R-MMU-4086400 | 81 | 12 | 8608 | 757 |
Psme1,Psmb6,Psmb9,Daam1,Psme2b,Fzd1,Fzd5,Psmd10,Psma6,Psme2,Psmb10,Psmb8 |